Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 AARS2 "AARSL, bA444E17.1, KIAA1270" ENSG00000124608 "Alanyl-tRNA synthetase 2, mitochondrial" Q5JTZ9 6 44298731-44313347 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration, Premature ovarian failure, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035636, HPA061396" Approved Enhanced Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA035636: AB_10670837, HPA061396: AB_2684502" "unprognostic (1.56e-1)" "unprognostic (3.24e-2)" "unprognostic (2.58e-2)" "unprognostic (2.04e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.83e-3)" "unprognostic (5.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-2)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.02e-1)" 4.7 5.2 6.5 5.6 6.2 5.4 4.9 9.4 6.7 7.6 6.7 5.8 6.5 6.1 3.2 9.2 6.4 4.6 6.0 6.8 5.1 5.7 6.9 4.3 6.0 6.1 5.8 8.3 6.5 5.9 6.3 4.1 6.4 7.0 4.1 5.4 6.2 4.3 4.8 7.2 7.9 4.1 5.4 7.2 5.4 3.7 6.0 6.2 6.2 3.3 5.3 5.6 7.4 6.7 14.6 9.9 13.9 23.8 8.1 7.2 18.3 10.9 5.7 11.2 10.6 11.4 7.1 16.3 16.2 4.8 12.2 10.0 14.7 16.0 4.7 10.9 23.7 18.9 10.6 14.5 4.8 17.9 16.0 5.9 9.8 9.0 10.2 7.3 9.5 21.8 21.0 15.4 6.2 16.0 14.2 15.9 9.9 40.3 9.8 16.4 8.7 10.4 6.7 12.7 32.0 11.4 9.4 10.9 15.5 9.7 9.9 21.6 8.4 12.1 13.5 7.6 13.9 8.8 8.7 16.5 6.8 15.9 22.1 2.2 1.1 0.1 1.3 1.3 2.1 1.5 1.9 1.7 1.0 2.9 1.8 1.7 0.2 1.9 1.4 1.3 1.2 1.3 6.5 6.2 9.4 6.7 6.8 5.1 6.1 5.8 6.4 5.4 6.0 6.7 2.6 6.4 3.3 5.2 3.7 0.6 2.1 1.9 4.0 6.6 2.8 2.7 3.5 5.7 2.8 0.0 12.5 5.0 4.9 3.0 0.0 2.3 10.1 3.5 5.4 3.0 0.0 8.2 5.5 0.4 5.0 3.4 5.1 6.2 0.0 5.9 3.9 2.5 3.3 0.0 9.0 2.2 2.0 2.8 1.8 1.0 4.7 2.5 0.0 1.9 3.9 2.0 4.1 3.0 3.6 1.4 0.7 4.5 6.9 1.6 6.3 1.0 3.0 7.1 0.0 4.7 2.8 4.3 6.1 4.4 0.4 5.3 4.1 4.5 3.7 1.6 ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 101.7;intestine: 70.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 95.8;Distal enterocytes: 109.9;Microglial cells: 570.6;Paneth cells: 106.2;Proximal enterocytes: 204.6" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cell line enhanced" "Detected in some" "CACO-2: 67.3;HEK 293: 20.4;HEL: 37.7;Hep G2: 18.5;RPTEC TERT1: 24.2;SH-SY5Y: 78.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 12.2" "CAB001716, HPA002199, HPA074614" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Plasma membrane" "Focal adhesion sites" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 101.7 14.1 3.9 13.6 1.9 3.6 13.7 17.6 6.4 5.3 16.6 26.4 11.0 3.6 3.1 5.0 15.5 1.9 15.3 15.6 33.7 28.0 6.4 3.2 17.6 14.4 2.2 2.0 1.4 0.5 2.3 19.7 4.2 18.2 2.2 1.2 3.1 0.2 1.5 70.7 9.8 15.1 4.2 2.1 0.9 19.3 2.7 1.9 1.4 3.5 3.6 1.7 14.3 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.1 4.3 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 20.4 37.7 4.2 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 24.2 0.2 0.9 78.9 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 4.0 0.0 0.9 7.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 11.1 0.0 27.2 0.8 2.7 6.8 0.0 2.5 1.7 6.6 0.2 17.9 0.0 0.1 0.0 2.5 14.1 13.6 13.7 17.6 15.3 15.6 17.6 14.4 19.7 15.1 19.3 14.3 17.1 0.0 3.0 3.9 9.9 0.8 0.1 0.0 1.2 1.9 0.4 3.9 3.0 95.8 0.6 49.7 0.0 5.8 24.7 109.9 5.9 13.8 27.3 0.6 0.6 52.9 0.0 7.8 16.1 1.9 0.2 3.7 0.0 0.7 3.8 0.3 2.5 38.4 0.4 0.0 11.4 15.8 0.0 0.6 1.2 3.8 0.9 1.6 0.0 570.6 0.2 0.2 32.0 6.0 3.2 8.1 106.2 0.0 4.6 0.2 204.6 57.7 0.7 1.1 0.0 0.4 1.3 0.4 0.9 0.2 0.6 9.9 24.5 0.1 19.9 0.3 ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" 10.4 11.6 0.3 4.0 0.2 3.6 8.6 0.3 0.7 10.4 4.1 16.1 1.1 11.0 0.1 22.8 7.0 3.1 11.2 0.3 0.5 8.0 2.3 15.5 4.4 1.1 0.8 8.9 8.9 3.6 7.2 2.0 0.7 15.2 0.7 0.4 9.2 0.9 21.2 9.7 12.4 6.3 0.5 15.7 15.0 13.1 0.6 4.3 21.0 0.1 1.1 15.4 12.8 0.9 4.3 43.7 0.3 11.7 3.2 4.5 0.5 15.4 19.0 13.1 13.8 6.7 34.8 7.0 79.6 29.6 11.0 12.1 3.4 12.4 4.6 22.2 4.4 16.4 22.0 16.3 25.1 5.9 39.5 15.0 9.0 1.1 2.3 3.8 10.2 28.6 17.8 6.8 0.5 5.4 12.0 0.9 3.5 1.8 8.2 41.9 7.8 5.3 0.7 15.2 6.4 11.8 18.9 17.8 3.6 11.9 6.2 0.8 3.5 0.4 2.0 11.4 11.9 13.5 7.4 3.3 6.6 0.6 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.5 1.1 0.8 0.7 0.5 0.6 0.9 8.6 25.6 5.6 10.7 13.1 8.8 8.5 18.2 9.6 3.1 4.4 3.7 6.0 4.3 14.4 5.5 22.9 0.9 9.8 2.7 3.9 9.1 11.0 15.7 12.9 8.6 18.6 16.0 26.6 6.2 3.2 12.3 49.5 17.8 22.1 16.8 8.6 0.4 8.5 5.0 38.5 6.6 14.2 21.4 9.1 14.3 7.5 12.2 3.6 11.2 10.5 1.2 5.2 12.1 15.9 11.2 4.5 6.8 15.7 18.7 0.5 1.1 9.9 8.8 0.0 6.4 5.1 4.9 6.6 18.1 5.1 0.5 17.4 37.1 3.7 11.6 ABCC2 "CMOAT, cMRP, DJS, MRP2" ENSG00000023839 "ATP binding cassette subfamily C member 2" Q92887 10 99782640-99852594 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.2;liver: 121.7" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 70.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 24.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "A549: 204.4;Hep G2: 208.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071145 Enhanced NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA071145: " "unprognostic (1.49e-3)" "unprognostic (5.92e-2)" "unprognostic (1.59e-1)" "unprognostic (3.67e-1)" "unprognostic (1.93e-2)" "unprognostic (2.33e-1)" "unprognostic (2.51e-1)" "unprognostic (7.15e-3)" "unprognostic (5.68e-2)" "unprognostic (2.01e-1)" "unprognostic (4.30e-1)" "unprognostic (1.40e-3)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.31e-1)" "unprognostic (3.22e-2)" "unprognostic (2.95e-1)" "unprognostic (1.26e-2)" 1.6 0.4 0.2 0.7 0.4 0.8 3.0 0.5 0.3 0.5 0.1 0.6 39.1 0.4 0.2 0.3 0.7 24.4 0.2 0.3 0.2 18.5 121.7 0.5 0.7 0.4 0.3 0.3 1.1 0.1 0.1 0.5 0.4 0.4 0.4 3.9 0.5 0.2 1.1 1.7 40.2 0.2 0.2 1.4 0.7 0.7 0.3 0.8 0.4 0.7 0.5 1.3 0.5 0.6 0.3 204.4 3.5 10.2 15.3 12.0 3.4 0.5 1.3 0.5 0.6 44.6 0.3 0.4 0.3 0.7 0.5 1.3 0.3 0.4 0.6 0.5 0.3 0.0 1.0 208.7 0.5 0.3 0.7 1.9 13.9 1.5 1.4 0.2 0.4 0.6 0.0 0.3 0.2 1.0 0.2 1.4 0.3 39.8 0.3 0.3 0.2 0.4 1.4 0.3 0.1 0.2 0.5 3.4 25.9 0.4 0.1 0.4 0.7 0.6 0.6 0.9 0.6 0.8 0.1 0.2 16.1 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.3 0.2 0.4 0.3 0.4 0.2 0.3 0.6 0.7 0.0 0.0 2.3 0.4 0.0 0.2 0.2 0.0 0.3 0.1 0.0 0.5 1.5 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 2.6 2.9 0.2 0.3 0.0 0.4 1.0 0.4 0.0 1.7 0.0 0.6 1.3 0.1 1.4 70.7 0.2 0.0 1.3 0.6 0.0 1.0 0.0 1.1 0.3 0.4 5.4 1.9 0.3 0.1 0.0 1.0 2.2 0.1 0.0 0.0 0.1 0.2 15.5 10.7 2.8 1.5 0.0 0.4 0.5 1.2 0.7 0.1 0.0 1.6 0.4 0.1 0.4 0.0 ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 231.6;Distal enterocytes: 265.1;Gastric mucus-secreting cells: 271.7;Hepatocytes: 192.9;Paneth cells: 194.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Cell line enhanced" "Detected in many" "A549: 79.4;CAPAN-2: 60.6;HeLa: 36.9;OE19: 89.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" 3.1 59.1 0.1 3.4 1.8 0.8 4.2 0.2 0.7 2.1 0.0 18.9 12.0 1.1 1.8 7.5 1.0 11.9 0.9 0.3 0.3 8.0 50.4 4.8 1.9 5.9 0.8 0.7 22.6 0.8 0.8 1.1 3.5 5.9 8.7 0.4 7.0 5.5 0.2 7.1 11.9 1.3 1.7 3.4 17.1 1.0 2.5 0.3 5.5 0.0 1.7 6.3 3.6 2.4 5.7 79.4 0.0 0.3 4.4 6.9 0.1 10.4 13.1 0.7 0.7 4.2 60.6 0.0 8.0 20.6 14.5 14.5 0.0 1.0 1.0 0.0 0.0 1.7 36.9 24.2 17.2 0.0 0.0 7.5 5.6 2.9 6.2 8.5 1.4 0.0 0.2 0.0 8.0 18.9 0.0 0.0 0.1 89.7 10.1 0.1 0.0 0.3 33.4 34.2 0.1 0.6 19.2 3.1 0.0 0.1 2.6 0.0 17.3 0.5 3.4 0.2 8.5 0.1 0.0 0.0 8.2 0.0 0.9 0.2 2.3 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.3 6.4 0.1 0.5 5.4 0.1 1.8 0.2 0.7 0.3 0.3 5.9 0.8 3.5 1.7 2.5 2.4 0.7 19.2 5.5 0.0 1.8 9.4 122.2 47.1 42.7 1.6 1.9 6.9 3.1 231.6 19.5 14.7 0.0 0.4 0.0 265.1 5.9 100.1 82.9 5.9 8.8 2.7 23.5 0.0 4.3 106.1 3.7 3.6 271.7 30.5 0.0 3.1 3.9 192.9 26.1 1.7 0.9 96.2 12.2 33.0 11.4 118.6 9.0 31.6 3.6 2.8 8.7 2.9 1.0 0.5 0.5 105.9 194.7 3.0 2.1 104.6 57.2 10.8 2.7 0.3 0.0 1.9 5.6 0.9 0.8 12.7 10.5 1.0 2.6 0.1 111.0 118.4 ABCC5 "EST277145, MOAT-C, MRP5, SMRP" ENSG00000114770 "ATP binding cassette subfamily C member 5" O15440 3 183919934-184017939 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 167.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 196.0;Inhibitory neurons: 122.8;Rod photoreceptor cells: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044067, HPA052295" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA044067: AB_2678797, HPA052295: AB_2681789" "unprognostic (9.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.83e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (4.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.02e-1)" "unprognostic (5.91e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (1.10e-1)" "unprognostic (9.05e-3)" "unprognostic (1.64e-1)" "unprognostic (3.33e-2)" "unprognostic (1.24e-2)" 15.4 23.2 42.5 16.3 44.2 22.4 13.1 48.4 50.0 30.9 167.1 24.4 10.8 21.6 10.4 44.5 16.1 17.9 47.2 45.5 43.6 41.6 7.9 15.6 13.1 44.0 39.5 23.4 13.0 24.0 41.7 17.2 44.7 27.8 22.1 126.2 18.4 13.7 117.5 24.1 23.2 16.1 34.0 37.1 82.3 16.5 46.3 15.3 13.8 40.3 11.8 34.8 35.2 43.2 21.5 11.5 25.9 30.8 25.7 28.3 40.0 16.8 13.3 14.8 16.2 17.9 15.8 22.5 38.6 16.2 22.6 83.3 32.1 18.6 19.3 24.4 31.1 48.1 32.5 18.0 10.3 14.8 36.5 45.6 18.3 15.9 10.6 30.3 17.8 65.6 45.6 30.8 25.7 56.7 40.7 17.1 26.7 38.4 21.7 28.1 8.7 13.4 54.4 136.4 46.6 27.8 17.1 93.5 29.3 33.3 56.6 4.9 20.4 17.4 16.6 22.3 23.8 11.7 24.3 21.1 12.5 29.2 17.9 11.7 4.6 8.3 6.9 2.2 4.4 3.1 3.8 3.1 3.6 4.5 4.3 6.0 16.4 5.6 4.2 1.3 5.7 4.5 42.5 44.2 48.4 50.0 45.5 43.6 44.0 39.5 44.7 34.0 46.3 43.2 8.3 9.6 5.3 39.2 6.4 8.9 14.4 18.3 35.3 39.1 10.5 11.3 37.2 2.8 37.2 44.1 196.0 3.2 7.7 23.3 7.9 5.7 6.0 10.4 18.0 9.5 59.3 21.2 101.3 4.5 5.0 12.5 91.3 20.8 5.1 31.0 6.8 3.3 49.7 33.7 122.8 6.4 20.3 32.7 6.5 3.5 8.1 29.3 12.4 32.8 8.3 13.8 9.2 82.4 62.7 7.9 20.2 7.9 7.5 9.3 5.1 4.8 44.9 121.1 0.0 27.4 15.4 6.8 18.8 41.3 12.1 4.5 8.6 14.9 7.5 61.5 ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 ABCG2 "ABCP, BCRP, CD338, EST157481, MXR" ENSG00000118777 "ATP binding cassette subfamily G member 2 (Junior blood group)" Q9UNQ0 4 88090150-88231628 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 88.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 106.7;Extravillous trophoblasts: 81.7;Hofbauer cells: 137.4;Microglial cells: 185.5;Proximal enterocytes: 216.6" "Cancer enhanced" "Detected in many" "glioma: 9.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 43.5;BEWO: 75.8;MCF7: 26.2;OE19: 58.6;RPMI-8226: 38.9;SuSa: 26.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037299, HPA054719" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Nucleoplasm "CAB037299: AB_476804, HPA054719: " "unprognostic (5.04e-1)" "unprognostic (3.05e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.14e-2)" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (4.52e-2)" "unprognostic (1.67e-3)" "unprognostic (8.82e-3)" "unprognostic (7.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.92e-1)" 2.3 4.0 30.8 1.0 29.1 2.3 4.0 30.0 33.1 22.1 17.4 15.7 48.2 23.1 6.8 2.3 9.8 5.1 2.9 25.4 32.3 3.5 36.0 5.1 1.2 40.1 31.3 8.3 0.8 4.4 8.9 11.7 40.1 7.1 13.9 2.5 5.0 33.8 0.3 0.6 88.3 19.8 31.1 1.4 1.9 3.0 40.0 1.3 6.4 0.9 2.0 2.3 4.0 31.9 1.7 43.5 11.9 0.0 0.4 0.0 75.8 1.9 1.3 2.1 3.5 9.8 0.5 0.0 0.4 0.3 5.4 13.2 0.4 1.2 3.1 13.2 1.9 0.6 0.3 13.0 0.0 0.6 0.1 0.2 5.1 4.8 0.3 1.2 4.1 1.0 1.1 0.0 1.3 26.2 6.3 0.2 4.1 58.6 0.0 3.2 0.0 38.9 0.1 9.5 0.2 0.5 8.9 0.9 1.2 26.1 0.3 0.1 0.0 1.7 1.6 0.4 0.2 11.9 4.7 0.0 3.1 0.0 1.8 0.0 0.0 0.0 0.7 0.0 2.2 0.0 0.2 0.2 0.0 0.5 0.2 0.1 0.0 1.1 0.1 0.2 0.8 0.2 30.8 29.1 30.0 33.1 25.4 32.3 40.1 31.3 40.1 31.1 40.0 31.9 9.4 3.2 1.1 3.9 0.9 3.8 0.3 0.0 0.0 0.4 24.3 1.9 1.6 1.5 0.2 0.0 0.0 16.8 0.6 106.7 1.9 0.0 3.3 0.4 3.8 45.8 3.0 20.6 1.1 0.2 81.7 2.4 0.5 0.5 5.7 0.2 31.4 23.4 137.4 0.0 0.7 12.0 0.0 1.3 2.5 1.2 1.2 2.8 5.4 185.5 0.1 0.7 2.1 11.1 0.9 0.1 44.3 0.4 2.0 0.2 216.6 7.6 0.8 0.9 0.0 0.4 4.3 1.0 4.3 1.1 0.4 37.6 1.0 4.3 6.1 0.2 ABI1 "ABI-1, E3B1, SSH3BP1" ENSG00000136754 "Abl interactor 1" Q8IZP0 10 26746593-26861087 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 278.2;Suprabasal keratinocytes: 270.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008375, HPA068407" Approved Approved "Plasma membrane,Cell Junctions" NA NA 440000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cell Junctions" "CAB008375: AB_592744, HPA068407: AB_2685983" "unprognostic (2.83e-3)" "unprognostic (8.69e-2)" "unprognostic (1.12e-1)" "unprognostic (3.96e-1)" "unprognostic (2.51e-2)" "unprognostic (9.24e-3)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (6.04e-2)" "unprognostic (4.38e-1)" "unprognostic (2.40e-2)" "unprognostic (5.48e-2)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" 28.9 16.2 28.5 35.0 29.2 83.8 29.8 28.3 38.9 30.4 20.9 32.0 32.4 23.6 19.2 53.0 23.8 24.9 16.3 37.4 28.8 27.6 24.9 28.1 48.1 24.7 26.8 26.6 19.9 20.1 12.9 28.3 25.4 20.8 33.0 18.9 32.9 19.1 20.0 42.9 34.1 23.8 26.2 32.3 31.8 14.2 28.0 44.5 22.6 19.6 53.7 34.7 36.5 27.1 55.0 28.6 21.1 21.9 34.4 39.5 34.1 50.9 31.2 35.0 37.5 33.7 61.7 101.1 23.2 51.7 23.0 57.7 28.0 37.0 41.0 65.2 24.2 44.5 18.0 29.0 23.6 23.2 43.9 28.1 54.6 35.3 21.8 41.5 43.7 33.5 30.7 67.2 40.5 25.4 49.8 26.0 18.8 37.5 13.5 51.4 41.2 69.2 48.0 22.9 17.1 18.5 41.3 44.5 46.8 29.4 27.7 35.5 50.6 27.3 33.2 34.4 25.5 15.0 24.0 108.7 38.7 61.1 17.4 77.3 35.5 91.4 42.1 43.2 40.8 57.2 40.9 48.5 39.4 47.7 37.7 41.7 64.3 35.8 45.4 34.1 76.5 57.2 28.5 29.2 28.3 38.9 37.4 28.8 24.7 26.8 25.4 26.2 28.0 27.1 44.4 41.7 37.7 278.2 89.3 246.2 127.9 74.0 123.5 9.6 40.5 26.5 23.2 38.6 73.5 25.8 2.1 36.4 75.7 69.7 13.7 56.3 11.3 72.1 41.3 41.9 44.9 43.8 81.6 52.1 46.9 45.9 42.3 111.5 57.7 22.3 32.9 25.6 75.8 16.8 133.7 54.9 83.4 80.5 116.3 5.7 22.1 92.1 92.5 106.8 89.8 48.2 73.2 128.7 47.4 82.2 52.1 22.2 56.8 132.5 52.7 39.0 86.2 10.0 32.9 29.8 40.3 14.7 10.8 109.6 270.6 77.2 71.0 27.2 41.3 195.4 ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713016-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 71.2;Oligodendrocytes: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Enhanced "Nucleoplasm,Nuclear bodies" Yes No "Cluster 37: B-cells - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: AB_1844453, HPA027280: AB_1844454, HPA028409: AB_10601011" "unprognostic (4.82e-2)" "unprognostic (3.99e-2)" "unprognostic (5.55e-2)" "unprognostic (4.72e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-3)" "unprognostic (1.89e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-2)" "unprognostic (1.09e-2)" "unprognostic (1.48e-1)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 50.9 30.7 27.4 25.3 38.9 23.4 45.8 33.6 31.4 60.5 40.4 96.4 23.1 63.0 11.6 33.8 55.6 35.7 36.1 26.6 28.3 23.1 17.5 37.3 16.3 39.3 38.5 56.0 24.9 32.5 34.9 26.5 35.8 43.5 26.7 14.2 32.4 33.6 29.4 36.3 45.2 41.2 31.3 23.3 51.6 20.1 34.9 22.4 46.7 30.8 15.4 79.3 42.7 41.3 22.5 48.3 53.6 62.9 76.5 93.3 18.8 38.8 60.4 44.8 38.1 36.4 28.3 32.3 22.3 52.0 47.6 42.5 23.5 36.0 30.7 20.6 16.3 23.7 84.1 33.4 51.8 36.5 32.3 68.8 37.2 80.6 50.0 64.1 61.0 47.9 135.8 26.5 54.9 42.0 49.2 30.5 57.9 34.3 33.8 55.9 67.9 35.9 45.0 25.7 47.9 60.1 66.1 23.5 29.2 31.0 46.2 33.1 71.1 170.7 44.1 66.3 62.6 8.4 20.3 47.9 72.1 27.6 55.1 0.0 0.7 0.3 0.6 0.4 0.8 1.3 0.6 0.6 0.7 0.4 0.6 0.5 0.0 0.8 1.9 1.0 0.3 0.6 27.4 38.9 33.6 31.4 26.6 28.3 39.3 38.5 35.8 31.3 34.9 41.3 16.2 9.6 13.6 54.9 4.7 9.2 7.3 9.8 5.2 8.2 11.6 10.2 6.2 7.2 7.2 14.7 12.5 13.6 12.1 21.2 1.9 14.4 5.9 8.6 29.7 18.1 22.1 4.6 52.5 11.1 4.3 36.7 5.6 12.4 2.5 22.1 20.3 15.9 16.6 10.1 63.7 17.5 6.1 16.4 11.7 8.8 28.0 10.2 5.4 71.2 6.6 19.2 6.2 66.9 116.0 17.9 18.3 25.6 5.6 8.6 11.6 10.3 7.8 9.1 19.7 29.5 19.8 16.9 16.5 6.6 6.8 15.2 7.9 20.1 21.4 7.2 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 166.8;Langerhans cells: 188.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "hTERT-HME1: 73.5;TIME: 70.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" 9.3 3.2 5.9 4.9 6.7 2.7 5.7 6.1 6.1 5.4 2.0 4.6 2.8 3.7 2.7 2.5 3.2 11.8 3.9 7.4 5.0 3.6 2.7 6.5 2.7 3.8 4.4 3.5 5.7 4.2 3.8 4.1 3.9 3.5 3.3 9.2 3.5 2.6 3.1 4.2 3.2 4.5 3.0 2.7 3.7 4.4 5.6 4.1 3.8 4.2 2.5 6.4 4.0 4.8 24.2 13.1 8.7 5.8 7.3 16.8 5.3 26.3 21.6 31.9 23.1 9.9 7.2 13.7 18.9 19.2 21.7 11.0 12.6 9.1 44.6 8.5 11.4 6.7 12.4 4.9 13.3 7.5 2.1 15.6 11.6 45.3 73.5 13.9 36.2 7.0 16.1 3.8 42.6 6.5 5.9 4.0 8.3 5.0 4.3 8.6 14.4 6.5 10.8 4.0 5.2 11.9 22.0 7.0 53.8 13.2 6.2 6.4 70.7 33.3 24.5 15.7 42.8 7.0 9.3 14.1 15.6 4.0 32.4 1.4 0.3 0.0 0.5 0.1 0.2 0.5 0.3 0.3 0.2 0.7 0.4 0.5 0.6 0.5 0.1 0.5 0.2 0.1 5.9 6.7 6.1 6.1 7.4 5.0 3.8 4.4 3.9 3.0 5.6 4.8 33.5 22.4 24.0 44.1 14.4 46.9 43.6 16.3 12.5 40.0 18.7 9.5 8.9 22.8 10.8 11.0 166.8 9.3 7.7 15.5 11.7 14.3 15.6 12.3 23.4 67.2 27.0 9.9 81.6 13.9 8.2 67.6 10.2 21.5 17.1 19.5 31.1 15.3 22.9 25.2 62.0 11.0 10.2 34.9 188.1 32.2 15.2 67.7 69.4 45.0 13.9 11.3 8.2 72.4 57.1 45.5 16.0 13.5 10.3 42.6 9.9 9.4 11.0 35.7 6.6 32.3 30.5 17.8 30.5 11.5 38.4 10.4 12.4 11.6 14.9 25.3 ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.6;Endothelial cells: 59.8;Fibroblasts: 171.2;Smooth muscle cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HeLa: 103.7;MCF7: 80.0;RT4: 312.3;SiHa: 97.0;U-2197: 328.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" 116.2 5.2 13.0 14.3 13.5 3.5 70.4 13.1 15.6 29.2 18.3 38.7 11.8 17.3 10.5 25.0 33.7 30.8 68.5 13.7 18.9 11.3 28.3 26.3 10.5 22.3 16.0 15.9 37.9 5.0 24.4 123.3 14.4 20.1 24.7 1.7 21.4 16.8 35.4 38.1 34.1 24.2 14.3 56.0 27.9 14.6 14.5 6.4 58.1 37.9 5.6 107.0 38.2 13.6 0.0 0.1 6.3 0.0 10.5 0.2 44.9 2.6 1.4 2.3 4.6 0.5 0.1 0.0 5.1 0.2 16.9 68.0 0.2 24.0 0.4 0.1 0.0 0.1 103.7 0.2 0.1 0.2 0.1 3.2 61.0 0.3 0.0 15.4 11.2 0.3 1.2 0.1 0.0 80.0 0.2 0.2 11.0 0.0 0.7 0.1 7.6 0.8 0.0 312.3 0.4 0.1 97.0 0.5 0.0 23.9 0.0 0.3 0.0 0.8 23.3 328.5 0.1 1.4 0.0 0.1 1.2 6.6 0.5 0.0 0.1 0.0 2.5 0.2 3.8 0.3 1.3 3.2 0.1 0.6 1.1 1.5 0.0 4.7 0.4 0.0 2.0 0.5 13.0 13.5 13.1 15.6 13.7 18.9 22.3 16.0 14.4 14.3 14.5 13.6 33.2 9.6 4.8 20.5 1.1 22.0 0.2 39.6 1.2 1.7 0.2 1.0 9.1 0.0 24.8 0.0 0.0 0.1 0.7 1.0 0.0 0.2 0.9 13.5 24.2 59.8 0.0 0.0 0.7 10.4 0.8 171.2 1.1 24.8 6.3 6.3 33.5 2.5 0.8 0.0 2.3 0.1 6.1 4.1 10.1 0.4 1.5 6.9 1.8 12.2 0.8 0.1 1.0 1.0 0.1 1.3 5.3 1.2 0.5 0.5 3.3 0.9 5.8 0.1 0.0 35.7 37.1 0.2 0.3 1.1 15.9 0.3 1.5 1.1 0.2 2.6 ACLY "ACL, ATPCL, CLATP" ENSG00000131473 "ATP citrate lyase" P53396 17 41866917-41930542 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007783, HPA022434, HPA022953, HPA022959, HPA028758" Enhanced Supported Nucleoplasm,Cytosol No No 3100000 "Cluster 44: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol Nucleoplasm "CAB007783: AB_562242, HPA022434: AB_1844513, HPA022953: AB_1844514, HPA022959: AB_1844515, HPA028758: AB_10603575" "unprognostic (2.21e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.41e-1)" "unprognostic (1.21e-2)" "unprognostic (2.83e-1)" "unprognostic (8.94e-3)" "prognostic unfavorable (3.66e-4)" "unprognostic (3.38e-3)" "unprognostic (4.11e-2)" "unprognostic (5.94e-3)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.88e-3)" "unprognostic (1.66e-1)" "unprognostic (9.36e-2)" "unprognostic (3.90e-2)" "unprognostic (4.67e-3)" 64.9 30.2 24.0 43.9 27.2 34.7 46.7 33.6 55.5 33.2 22.5 35.4 49.3 34.4 34.7 30.5 36.0 31.1 27.1 24.7 66.5 47.5 27.5 35.3 42.7 80.3 48.6 21.3 46.3 37.4 22.4 42.4 76.5 62.6 35.7 23.2 39.1 28.5 15.3 28.9 43.7 42.5 34.2 39.1 38.9 32.2 43.1 48.4 30.8 14.9 40.3 36.7 29.2 43.7 127.1 423.2 194.8 168.8 296.1 274.4 178.3 174.0 188.0 213.7 266.3 217.9 141.8 204.7 108.8 245.2 200.6 197.2 253.9 298.0 177.8 184.9 243.0 117.3 228.3 227.5 136.9 191.9 147.1 219.8 88.3 376.9 75.6 140.0 228.7 155.0 147.4 158.5 180.4 130.0 317.8 107.6 127.6 84.8 75.7 205.2 236.2 262.2 221.0 222.4 364.7 200.2 124.5 382.8 133.7 167.6 229.4 181.0 248.4 165.7 135.5 169.0 291.0 91.9 127.0 193.0 280.3 145.7 137.5 32.2 29.2 36.5 30.9 30.9 29.1 21.6 24.4 27.7 33.0 18.3 18.1 20.3 14.6 24.0 39.8 19.1 34.3 33.8 24.0 27.2 33.6 55.5 24.7 66.5 80.3 48.6 76.5 34.2 43.1 43.7 28.2 28.9 26.2 12.4 20.5 25.0 10.0 25.4 12.5 12.1 38.6 21.6 12.6 31.5 21.0 23.9 4.2 22.6 25.9 26.7 11.7 33.8 73.3 31.6 35.3 33.4 65.9 34.3 10.9 33.6 46.5 28.9 23.4 29.2 15.2 28.7 41.4 53.0 31.0 18.5 14.7 54.0 20.3 39.0 25.9 17.5 61.8 27.6 32.0 16.9 42.9 7.6 25.7 11.6 13.6 42.9 16.2 51.1 17.4 35.9 40.4 87.0 31.1 9.4 13.1 17.6 25.7 17.9 36.0 21.6 33.0 22.2 25.1 49.0 22.2 15.5 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368298 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 76 "prostate: 3643.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Hofbauer cells: 4.7;Syncytiotrophoblasts: 8.9" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 139.7" "Lineage enhanced" "Detected in many" "granulocytes: 139.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.7;OE19: 22.3;RPMI-8226: 58.0;U-698: 17.2;U-87 MG: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" NA NA 460000 480000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 3.1 5.4 0.9 7.3 1.3 17.5 3.4 0.9 0.9 6.3 1.2 3.6 3.1 1.4 17.2 47.7 2.2 1.5 0.6 1.2 1.5 28.9 1.4 4.5 1.9 1.5 1.3 1.1 2.7 3.9 0.5 10.8 1.5 3643.7 6.5 0.4 10.6 0.8 0.2 27.0 3.4 1.8 1.0 1.8 3.2 2.4 1.0 1.0 2.4 0.2 6.5 1.8 12.1 1.7 0.5 0.1 0.0 0.0 0.2 0.9 11.7 0.3 17.7 0.1 0.0 0.4 0.4 10.6 0.8 0.0 0.1 4.8 0.0 0.1 0.0 0.1 0.5 2.0 0.4 0.2 0.2 7.3 0.1 1.1 1.6 0.1 0.0 0.2 0.0 0.0 0.1 2.7 0.2 0.1 0.0 13.5 0.7 22.3 2.1 0.1 0.0 58.0 5.0 6.5 0.0 4.1 0.1 2.0 0.6 1.7 0.3 6.5 0.0 0.1 0.1 2.5 0.1 0.8 0.4 17.2 14.9 12.7 0.2 0.1 30.2 139.7 0.2 26.9 0.2 0.7 0.0 0.0 35.3 0.0 0.0 0.0 26.4 2.6 25.8 2.4 0.0 10.1 0.9 1.3 0.9 0.9 1.2 1.5 1.5 1.3 1.5 1.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157876330 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" 20.8 10.4 17.3 12.9 12.7 1.8 18.8 14.0 15.4 28.1 17.4 16.5 10.9 24.4 32.7 11.3 17.0 24.2 19.7 26.3 12.8 26.4 22.7 17.5 8.8 13.7 12.9 21.2 10.0 8.5 10.9 17.6 13.7 15.1 12.6 6.3 18.8 15.3 21.5 13.9 10.5 34.5 12.6 8.3 14.7 5.2 16.3 7.5 40.5 13.3 8.2 20.9 15.5 11.8 6.1 13.1 14.4 18.5 65.0 70.6 18.9 43.4 71.3 33.7 36.1 10.1 13.4 0.2 18.2 45.6 32.3 16.9 10.5 22.5 36.8 43.0 8.7 25.7 7.2 14.4 54.7 2.0 28.5 89.5 41.4 69.8 84.2 42.8 38.7 6.7 9.5 6.7 45.2 11.1 0.4 0.4 21.4 8.7 21.7 4.1 19.6 5.7 45.4 24.5 12.4 14.9 17.0 9.7 64.5 22.2 5.3 7.0 54.0 50.9 16.8 25.3 17.1 4.7 3.5 0.3 52.2 1.6 58.1 2.9 1.7 0.1 0.5 1.0 0.7 0.8 4.9 1.3 1.3 0.2 1.6 0.7 0.2 1.2 1.4 1.4 6.6 1.1 17.3 12.7 14.0 15.4 26.3 12.8 13.7 12.9 13.7 12.6 16.3 11.8 9.6 9.6 9.0 22.9 1.8 9.8 7.7 12.6 12.5 10.4 8.0 9.8 12.7 11.5 12.4 7.3 0.0 8.4 1.1 4.8 5.9 9.9 1.0 5.9 12.9 17.3 4.2 1.7 34.0 17.8 5.3 20.3 8.2 6.5 5.1 4.2 18.2 13.3 7.0 3.3 34.2 4.5 24.4 13.0 8.7 2.0 20.2 7.6 3.6 106.8 5.5 6.6 2.1 42.3 22.9 17.2 4.1 15.8 6.4 13.0 3.7 15.5 13.6 2.1 13.1 16.3 19.3 0.4 2.7 4.0 7.5 10.5 4.3 3.5 4.3 8.8 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951699-51997078 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB026126: , HPA063761: AB_2685115" "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 16.5 10.3 20.7 10.0 20.8 13.5 13.2 13.6 23.4 13.9 9.1 24.6 28.2 8.8 18.0 20.9 15.3 12.2 10.1 21.5 13.3 34.3 29.9 14.7 6.4 12.5 13.9 9.4 40.7 52.7 14.7 11.1 13.1 14.0 24.4 17.4 32.8 15.3 13.1 45.6 26.1 8.1 9.5 8.8 24.9 15.7 16.1 7.6 11.4 8.8 7.4 12.6 18.8 18.3 11.4 24.3 18.6 10.3 20.9 16.2 10.5 12.6 14.2 13.1 9.9 49.5 17.1 5.0 17.2 13.8 14.6 19.6 17.8 15.2 13.5 7.3 21.0 12.3 5.9 15.6 23.8 19.9 43.8 32.0 19.4 14.8 18.6 13.9 18.7 17.7 13.3 14.9 11.8 23.2 19.1 17.2 18.0 24.0 8.5 10.2 14.4 6.4 37.2 17.0 23.5 19.5 13.6 19.2 9.0 13.1 21.1 12.8 12.0 9.0 13.6 10.2 6.1 9.0 6.8 6.7 9.7 9.4 11.8 2.5 1.2 3.9 0.3 1.8 0.5 0.0 0.3 0.3 0.7 0.2 0.8 0.4 1.0 0.0 2.2 0.3 0.5 0.3 20.7 20.8 13.6 23.4 21.5 13.3 12.5 13.9 13.1 9.5 16.1 18.3 8.0 3.2 13.4 8.1 2.9 18.6 10.1 9.2 23.3 45.3 11.3 8.6 5.9 17.2 12.0 25.8 29.2 0.7 2.0 49.7 3.9 17.7 2.9 12.3 8.1 10.9 24.6 0.8 34.8 14.4 0.8 12.6 19.9 9.0 11.4 9.4 17.9 24.4 4.0 37.0 30.2 28.7 2.0 16.7 5.3 8.4 9.9 10.0 7.2 9.4 10.1 8.8 1.0 21.6 11.3 13.3 22.1 9.4 2.3 15.1 31.8 17.0 15.8 24.5 6.6 17.5 12.2 3.8 16.5 17.7 25.3 0.5 4.6 5.6 24.7 15.5 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Inhibitory neurons: 63.4;Oligodendrocyte precursor cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 26.3;RH-30: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 7.3 4.0 6.2 4.6 7.4 3.3 7.0 10.8 6.4 5.4 1.0 6.3 7.7 5.2 6.6 7.2 4.5 7.7 3.7 7.5 7.5 5.6 7.4 4.6 3.1 2.6 4.5 4.5 4.4 4.3 3.9 7.7 3.9 6.8 6.5 8.3 7.5 5.2 17.5 19.5 9.3 7.0 3.8 4.0 6.8 6.4 8.6 2.3 6.7 6.3 3.9 7.4 7.4 4.6 1.8 2.1 13.2 5.0 7.3 4.7 5.4 4.1 5.0 6.9 12.0 5.8 8.1 0.1 3.6 6.7 2.5 6.2 12.0 6.1 8.8 1.4 7.3 0.9 3.6 10.2 26.3 1.0 0.9 8.1 7.3 4.5 8.9 5.2 5.3 1.6 2.0 3.5 4.7 4.8 0.4 0.8 14.9 5.5 3.6 0.2 23.3 1.3 5.6 11.5 13.0 7.3 3.5 4.2 5.4 5.6 2.5 1.4 4.1 6.4 7.5 6.1 2.9 1.0 0.3 2.4 3.9 0.5 5.2 0.2 1.7 0.2 0.6 2.0 0.2 0.1 2.4 1.1 1.3 0.3 1.5 0.3 0.0 4.8 2.0 1.7 0.2 0.7 6.2 7.4 10.8 6.4 7.5 7.5 2.6 4.5 3.9 3.8 8.6 4.6 13.7 6.4 7.0 26.8 1.5 29.7 6.9 9.5 13.1 15.4 6.8 12.4 7.9 17.2 10.7 7.3 14.6 4.9 6.0 16.5 1.9 6.3 5.3 6.4 12.2 11.9 9.0 0.0 62.5 6.3 2.5 17.4 6.6 5.7 0.0 2.2 11.7 12.1 5.4 11.8 63.4 12.9 8.2 7.3 18.9 2.1 9.9 5.7 10.6 33.7 7.2 3.3 6.2 84.9 34.1 7.6 10.0 11.3 5.2 7.7 23.7 5.8 10.2 9.4 32.9 8.3 10.9 18.2 14.1 14.4 29.8 5.3 5.9 2.9 11.7 11.8 ACVR2B ActR-IIB ENSG00000114739 "Activin A receptor type 2B" Q13705 3 38453890-38493142 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.9;NTERA-2: 25.9;SuSa: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025115, HPA040384" Approved NA No "Cluster 54: Non-specific - Microtubule organization" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "CAB025115: , HPA040384: AB_2732484" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.47e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.32e-2)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (1.64e-1)" "unprognostic (1.98e-1)" "unprognostic (1.83e-1)" "unprognostic (4.75e-1)" 1.1 2.8 3.2 0.6 3.2 0.2 1.7 5.2 2.8 1.9 1.0 1.5 0.9 1.7 1.7 0.7 1.9 0.6 1.4 2.6 3.0 1.8 2.2 1.3 0.7 2.6 3.2 2.9 2.5 3.3 2.0 2.5 2.6 1.3 1.1 6.5 1.7 1.3 6.0 0.7 1.1 0.9 2.3 1.0 1.5 2.5 2.9 4.1 1.6 2.8 0.6 1.4 1.4 3.6 1.1 1.8 20.9 1.8 0.8 0.5 11.2 0.4 0.7 0.4 0.9 3.1 1.4 0.1 1.6 0.5 0.6 1.3 8.1 1.3 1.1 3.2 5.2 5.6 3.5 4.6 1.0 4.0 2.0 0.8 1.2 0.6 2.3 1.3 1.4 8.0 9.4 1.8 0.4 1.7 6.9 2.5 25.9 1.1 0.9 2.2 7.0 1.4 1.3 2.6 4.9 8.5 0.6 3.2 3.0 14.7 1.7 5.2 1.2 0.7 3.3 0.5 1.8 5.0 7.3 1.2 0.7 3.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 3.2 5.2 2.8 2.6 3.0 2.6 3.2 2.6 2.3 2.9 3.6 7.0 6.4 6.1 9.4 0.7 4.0 4.6 2.1 4.0 23.0 5.2 5.0 15.0 2.8 3.6 0.0 22.9 8.5 1.3 3.1 0.0 3.6 11.3 8.7 7.0 7.5 7.2 0.4 12.6 3.8 7.6 3.8 2.6 5.3 1.3 17.9 7.9 8.7 2.6 21.9 17.0 4.1 0.0 2.2 6.4 15.8 11.8 2.4 7.2 5.6 0.7 7.6 0.0 15.1 17.2 3.2 5.3 7.9 1.4 5.2 4.8 3.1 7.1 25.4 0.0 9.7 7.7 11.4 17.9 1.8 4.0 6.2 2.6 7.4 4.4 3.9 ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 377.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 296.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 14.9 8.7 11.4 19.0 18.6 18.7 15.2 20.2 15.0 16.0 9.7 22.2 15.9 16.3 7.7 15.4 13.9 18.9 12.1 12.2 12.7 18.0 16.1 21.0 22.2 18.2 17.6 14.1 8.8 7.9 8.2 29.0 17.5 25.2 17.2 10.8 9.3 12.2 6.1 16.9 17.5 13.3 13.7 29.0 20.3 8.5 15.5 42.7 28.6 7.1 16.4 28.0 10.4 25.2 48.4 88.5 27.6 31.2 34.8 49.8 70.0 39.0 116.0 28.6 39.1 39.9 62.6 22.7 118.0 35.2 49.2 95.9 16.8 43.5 37.0 30.1 19.3 38.7 35.1 42.1 40.8 25.0 103.8 44.4 30.0 19.9 29.2 41.1 55.6 45.0 24.5 57.9 50.4 15.4 89.5 32.0 40.2 15.4 14.6 36.4 91.6 57.1 66.6 121.4 29.9 20.3 44.0 52.8 73.1 60.0 30.4 55.0 41.4 37.1 41.2 296.6 39.6 30.7 70.7 23.5 54.1 50.8 67.3 30.9 36.2 19.2 12.8 41.1 19.2 8.3 12.7 11.6 23.6 9.6 12.7 10.8 51.5 17.7 48.6 10.2 18.2 25.8 11.4 18.6 20.2 15.0 12.2 12.7 18.2 17.6 17.5 13.7 15.5 25.2 60.1 83.3 50.8 83.2 37.9 26.6 30.7 33.3 33.0 22.7 61.6 30.9 40.0 30.0 46.7 80.9 27.1 35.6 69.4 79.0 1.9 56.0 21.2 39.5 56.4 72.5 36.1 20.8 106.1 31.8 57.8 36.1 53.0 74.0 30.3 31.5 71.4 36.2 63.8 45.4 96.2 43.6 36.7 90.1 28.9 19.4 18.0 77.9 46.2 147.1 69.0 30.6 44.3 75.9 377.6 48.9 48.1 17.0 51.0 89.1 45.1 23.7 41.2 33.4 13.1 34.4 42.8 20.3 17.8 39.5 22.3 26.5 51.3 34.1 39.5 83.9 ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 179.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" NA NA 740000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" 34.2 28.0 7.1 28.8 8.2 2.1 21.5 8.5 8.3 34.8 11.4 32.9 24.5 29.7 15.2 29.7 19.3 47.1 32.1 6.0 8.4 34.9 13.5 51.4 9.7 10.2 7.5 16.8 12.7 52.5 7.8 47.4 9.0 34.9 41.7 18.5 54.9 34.8 24.1 16.1 23.0 51.6 9.4 24.0 44.2 11.1 10.6 5.9 39.9 25.0 13.2 56.1 24.3 11.5 188.3 163.6 63.5 32.6 117.2 374.0 67.0 259.6 382.4 191.7 177.9 82.7 147.1 10.1 86.1 247.2 156.7 79.5 30.8 249.7 373.2 6.9 21.5 12.1 102.8 73.0 226.4 8.9 19.1 287.5 139.2 193.3 212.7 341.0 268.9 15.2 21.5 53.2 406.2 25.0 7.2 4.4 8.3 175.2 46.7 3.8 106.3 27.6 299.3 62.4 6.4 11.5 78.4 90.9 57.8 72.9 67.3 12.0 374.2 109.9 97.9 213.9 124.1 12.9 29.5 7.7 175.8 12.0 72.1 0.3 4.0 0.5 0.1 1.3 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 0.5 0.8 0.6 0.3 0.1 0.9 7.1 8.2 8.5 8.3 6.0 8.4 10.2 7.5 9.0 9.4 10.6 11.5 14.4 48.1 37.0 16.0 3.8 35.9 66.6 78.3 26.7 19.3 23.4 9.8 49.7 24.3 82.1 35.0 20.9 24.1 8.9 44.4 3.9 90.2 14.4 42.1 35.3 20.5 10.7 2.5 47.5 115.4 85.1 42.0 80.5 82.1 5.1 26.4 25.0 7.5 125.9 5.0 38.0 32.2 44.7 60.2 44.8 7.8 28.6 54.7 21.4 33.7 21.8 17.5 1.0 30.7 26.7 179.4 30.6 24.8 5.2 108.7 24.9 41.1 51.9 25.1 13.1 31.3 31.9 4.3 2.5 20.2 21.5 34.3 5.6 11.2 32.7 103.8 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADAMTS14 ENSG00000138316 "ADAM metallopeptidase with thrombospondin type 1 motif 14" Q8WXS8 10 70672506-70762441 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.9;gallbladder: 6.7;placenta: 7.6" "Group enriched" "Detected in some" 5 "Oligodendrocytes: 44.8;Paneth cells: 14.6;Theca cells: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.1;K-562: 10.4;RH-30: 5.4;U-138 MG: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (5.98e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-3)" "unprognostic (2.40e-1)" "unprognostic (5.33e-3)" "unprognostic (2.35e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.98e-2)" "unprognostic (6.81e-2)" "unprognostic (3.84e-13)" "unprognostic (3.90e-2)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" "unprognostic (2.16e-2)" 0.8 0.2 2.6 3.2 5.9 0.6 0.3 2.0 5.4 1.0 0.4 2.7 2.3 0.7 0.4 1.0 0.5 6.7 0.7 2.9 3.7 0.5 0.3 1.7 1.1 3.2 4.3 0.2 0.2 0.0 0.1 7.6 3.2 0.6 1.8 0.0 0.8 0.1 0.1 1.3 3.2 2.2 1.4 0.4 1.4 0.5 10.9 0.4 0.2 0.3 0.7 2.5 0.4 9.9 0.0 0.0 0.1 0.3 0.2 4.0 0.0 1.0 3.2 0.3 1.7 0.0 9.1 0.0 0.7 1.7 0.4 0.7 0.0 0.0 0.1 3.6 0.0 0.3 0.0 0.2 0.0 0.0 2.4 0.3 0.1 0.8 0.2 1.0 0.0 0.0 10.4 0.0 1.3 0.0 0.0 0.9 0.3 0.1 0.0 0.0 5.4 0.2 0.0 0.0 3.4 0.5 0.0 0.1 0.3 0.1 0.0 0.0 0.0 8.9 0.1 0.7 0.5 0.8 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.9 2.0 5.4 2.9 3.7 3.2 4.3 3.2 1.4 10.9 9.9 0.1 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.1 0.5 0.1 0.3 0.0 2.1 0.3 0.0 0.1 2.1 0.0 0.2 4.5 0.1 0.0 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.0 44.8 0.1 14.6 0.0 0.1 0.0 0.7 0.0 1.4 0.0 0.0 1.8 1.1 0.0 0.0 0.2 0.1 0.4 0.0 17.9 0.5 0.1 ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;placenta: 20.6" "Cell type enhanced" "Detected in some" "Adipocytes: 36.8;Granulosa cells: 15.0;Muller glia cells: 13.7;Oligodendrocytes: 16.9;Rod photoreceptor cells: 7.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 11.6;HUVEC TERT2: 8.0;SuSa: 10.6;TIME: 2.5;U-87 MG: 4.8" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Yes NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" 3.1 0.1 1.3 0.3 3.0 0.0 2.9 11.0 2.5 1.2 0.5 0.0 0.1 0.8 0.0 0.1 0.2 0.6 0.0 1.8 2.7 0.2 0.0 0.1 0.1 4.3 2.4 0.1 0.3 0.0 0.8 20.6 3.7 0.4 0.0 2.0 1.3 0.1 0.6 0.1 0.0 0.6 1.7 0.0 0.0 0.2 2.4 0.9 0.0 0.0 0.0 0.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.6 0.0 0.5 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 3.0 11.0 2.5 1.8 2.7 4.3 2.4 3.7 1.7 2.4 5.9 36.8 0.0 0.0 4.6 0.1 0.1 0.1 0.0 0.0 1.8 1.5 4.3 0.6 0.0 0.0 1.8 2.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.3 0.0 15.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.1 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.0 0.0 ADAMTS20 GON-1 ENSG00000173157 "ADAM metallopeptidase with thrombospondin type 1 motif 20" P59510 12 43353866-43552203 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.1" "Group enriched" "Detected in some" 4 "Bipolar cells: 5.1;Inhibitory neurons: 16.1;Oligodendrocyte precursor cells: 11.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "medulla oblongata: 2.8;pons: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 3.6;NB-4: 1.6;NTERA-2: 2.8;SuSa: 2.2;U-266/70: 4.0;U-266/84: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027608, HPA027609" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA027608: AB_10600098, HPA027609: AB_10599024" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.04e-1)" "unprognostic (9.61e-2)" "unprognostic (3.29e-1)" "unprognostic (6.67e-2)" "unprognostic (2.26e-1)" "unprognostic (1.05e-4)" "unprognostic (7.42e-2)" "unprognostic (2.02e-1)" "unprognostic (9.81e-3)" "unprognostic (2.57e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.5 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.1 0.0 0.0 1.6 2.8 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.2 0.7 0.0 0.0 0.0 0.3 0.0 0.0 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 2.8 0.1 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Excitatory neurons: 50.2;Leydig cells: 19.9;Rod photoreceptor cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;AN3-CA: 7.8;HEL: 14.1;K-562: 12.3;SH-SY5Y: 7.0;U-2 OS: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Intermediate filaments" "HPA021368: AB_2670681, HPA021369: AB_2670682" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-3)" "unprognostic (6.11e-2)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (1.60e-3)" "unprognostic (5.92e-4)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (8.63e-3)" "unprognostic (1.65e-3)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-4)" 2.3 0.8 0.5 1.0 2.5 0.8 3.2 0.0 1.5 0.4 0.1 0.3 0.1 1.9 1.7 0.2 2.9 0.6 0.9 1.5 0.6 0.9 0.2 1.1 0.8 0.0 0.2 2.0 0.3 2.7 0.2 0.7 0.1 0.7 0.3 8.4 0.4 1.1 0.2 0.4 0.2 1.7 0.0 0.7 0.5 1.9 0.1 0.6 1.2 0.3 0.3 1.3 0.4 0.4 0.0 0.0 13.2 7.8 0.1 0.3 0.1 0.7 2.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.8 0.0 1.8 0.0 1.8 14.1 0.9 0.0 0.2 0.0 0.0 1.7 0.1 0.6 0.1 3.3 0.0 0.0 12.3 0.0 0.0 0.0 1.3 0.0 2.2 0.0 4.0 0.0 2.6 0.0 4.6 0.0 0.5 7.0 0.0 0.6 0.2 1.4 0.1 0.2 0.1 5.6 8.5 0.0 0.7 0.0 0.0 0.0 1.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.5 1.5 0.6 0.0 0.2 0.1 0.0 0.1 0.4 1.8 0.0 3.4 7.5 0.0 0.5 0.9 0.0 0.0 0.9 0.8 3.2 1.2 1.5 1.3 1.8 14.6 0.0 0.0 0.0 0.0 0.0 4.1 2.2 5.1 3.7 0.0 2.5 50.2 0.0 0.3 3.3 0.0 0.7 1.3 1.9 3.9 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.7 1.9 19.9 0.3 0.0 1.0 0.0 1.8 0.0 7.1 1.3 0.0 0.0 4.5 0.0 1.1 0.0 0.3 0.5 12.9 0.0 0.3 1.2 1.2 0.8 0.3 0.0 0.0 0.0 2.8 0.0 0.1 ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.8;ovary: 95.9" "Cell type enhanced" "Detected in many" "Adipocytes: 80.3;Endothelial cells: 115.5;Fibroblasts: 88.8;Oligodendrocytes: 56.0;Sertoli cells: 52.6;Smooth muscle cells: 313.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 4.4" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 11.8;HUVEC TERT2: 14.4;SH-SY5Y: 7.9;TIME: 12.2;U-138 MG: 7.4;U-251 MG: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" NA NA 11000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" 116.8 9.8 6.1 16.3 31.5 0.7 43.4 31.1 19.2 16.4 5.8 18.2 0.8 15.0 0.2 6.2 34.6 14.3 53.6 8.1 15.2 26.0 8.7 50.3 1.6 38.2 29.6 95.9 9.0 2.1 13.0 3.2 31.6 16.9 2.0 1.5 5.2 0.5 13.3 5.0 9.4 10.5 28.3 1.8 22.8 1.8 26.2 1.1 21.3 0.4 0.3 31.8 12.2 48.0 0.0 0.0 0.2 0.1 6.4 4.0 0.6 5.4 0.2 0.5 3.0 0.2 0.2 0.2 4.4 1.7 0.0 0.1 0.0 0.0 1.9 0.1 0.3 0.2 0.5 1.3 0.6 0.0 0.1 4.5 0.0 11.8 0.1 0.0 14.4 0.1 0.2 0.3 0.4 0.1 0.0 0.2 5.3 0.0 0.0 0.1 5.1 0.1 0.0 0.1 0.1 7.9 0.0 0.1 0.1 0.3 0.2 0.5 12.2 7.4 0.1 0.4 10.8 0.2 0.1 0.1 2.2 0.1 0.1 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.0 4.4 0.2 0.1 6.1 31.5 31.1 19.2 8.1 15.2 38.2 29.6 31.6 28.3 26.2 48.0 80.3 0.0 4.1 0.0 0.2 31.2 3.2 0.0 2.2 2.2 8.6 5.5 5.5 0.0 0.6 0.0 0.0 0.3 0.5 0.2 0.0 0.3 0.0 0.3 13.0 115.5 0.0 0.0 0.4 0.0 0.3 88.8 0.5 0.5 0.0 0.3 43.2 0.9 1.0 3.3 0.1 0.0 0.0 1.0 32.6 0.2 0.3 3.2 35.6 2.8 1.0 0.5 0.0 0.0 56.0 0.0 0.0 1.2 0.7 9.8 0.0 0.1 0.0 1.0 52.6 21.2 313.7 2.7 0.6 2.7 19.0 0.4 3.7 1.6 0.3 7.7 ADAMTS5 "ADAMTS11, ADMP-2" ENSG00000154736 "ADAM metallopeptidase with thrombospondin type 1 motif 5" Q9UNA0 21 26917922-26967088 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 26.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 38.2;Endometrial stromal cells: 72.1;Fibroblasts: 88.6;Leydig cells: 62.7;Skeletal myocytes: 110.2;Smooth muscle cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.9;fHDF/TERT166: 11.9;RH-30: 33.1;U-87 MG: 13.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA005661, CAB025996, HPA030906, HPA030908" Approved Supported Nucleoplasm "Secreted to extracellular matrix" NA NA 28000 "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB025996: , HPA005661: AB_1078101, HPA030906: AB_2673654, HPA030908: AB_2673655" "unprognostic (1.97e-1)" "unprognostic (2.88e-3)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (4.67e-1)" "unprognostic (2.10e-2)" "unprognostic (4.38e-8)" "unprognostic (1.11e-3)" "unprognostic (7.66e-2)" "unprognostic (6.17e-2)" "unprognostic (8.13e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (6.69e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.15e-1)" 17.5 0.8 0.3 1.0 0.6 0.0 10.8 3.3 0.3 8.8 2.6 2.7 0.8 12.5 2.4 1.6 4.2 1.6 3.3 0.5 0.9 2.5 1.4 1.0 0.6 1.4 0.9 16.6 0.4 1.5 0.4 26.2 0.9 3.0 1.3 0.6 2.0 1.8 2.0 4.2 3.4 7.5 1.5 7.7 2.2 0.8 0.4 0.3 6.8 3.7 0.1 4.2 3.6 1.2 0.0 0.0 0.0 0.0 31.6 13.9 0.0 1.7 0.2 1.4 0.6 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 2.3 0.0 1.3 0.0 0.3 0.0 3.5 0.1 0.0 8.0 0.0 1.1 0.2 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 33.1 0.0 3.4 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 8.3 0.4 1.9 0.9 0.0 0.0 0.0 13.0 0.1 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.3 0.3 0.5 0.9 1.4 0.9 0.9 1.5 0.4 1.2 24.3 0.0 0.5 0.3 0.1 2.9 0.2 0.4 0.0 9.8 1.5 38.2 2.7 0.0 0.6 3.7 0.0 1.1 0.3 0.0 0.0 0.0 6.4 2.0 72.1 10.6 1.8 0.0 0.5 0.2 1.6 88.6 0.0 1.3 0.0 3.0 3.3 0.0 1.9 0.0 11.6 0.0 0.0 0.0 4.6 1.0 62.7 1.4 3.6 3.7 4.0 0.1 0.0 12.5 0.2 0.0 0.0 9.1 0.0 0.3 0.0 2.2 0.0 0.2 13.1 110.2 44.9 0.3 0.9 0.4 3.0 2.7 0.8 20.0 0.0 0.1 ADAMTS6 ADAM-TS6 ENSG00000049192 "ADAM metallopeptidase with thrombospondin type 1 motif 6" Q9UKP5 5 65148738-65481920 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.6;Inhibitory neurons: 63.6;Microglial cells: 31.9;Oligodendrocyte precursor cells: 139.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "BJ: 12.6;HBF TERT88: 13.4;hTEC/SVTERT24-B: 12.6;hTERT-HME1: 14.9;TIME: 14.5;U-2197: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043441 Enhanced "Secreted to extracellular matrix" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043441: AB_2678484" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.70e-3)" "unprognostic (4.33e-2)" "unprognostic (1.03e-2)" "unprognostic (2.39e-2)" "unprognostic (8.24e-2)" "unprognostic (1.65e-2)" "unprognostic (4.77e-2)" "unprognostic (8.04e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-6)" "unprognostic (3.23e-5)" "unprognostic (2.09e-1)" "unprognostic (3.02e-4)" "unprognostic (4.18e-3)" 0.5 0.1 0.2 0.6 0.2 0.0 0.3 0.2 0.3 0.3 0.5 0.3 0.1 1.1 0.7 0.2 0.6 1.4 0.3 0.2 0.6 0.2 0.0 0.5 0.4 0.3 0.4 0.3 0.0 0.0 0.1 1.9 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.1 0.6 0.6 0.3 0.7 0.3 0.5 0.3 0.2 0.1 0.1 0.3 0.7 0.3 0.2 2.7 0.0 0.6 0.6 0.0 2.0 0.0 12.6 7.4 7.7 9.0 0.0 0.3 0.0 0.1 4.8 5.3 0.5 0.1 2.4 13.4 2.0 0.0 0.2 5.1 0.3 0.4 0.0 0.7 0.9 0.0 12.6 14.9 3.7 6.9 1.3 0.0 0.0 4.8 0.0 0.7 0.0 0.1 0.3 0.1 0.4 2.6 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.0 1.6 0.0 0.1 14.5 3.0 4.5 16.2 10.2 0.1 0.0 0.0 3.4 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.4 2.1 0.1 0.2 0.0 1.3 0.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.6 0.3 0.4 0.3 0.3 0.3 0.2 11.3 0.0 0.0 4.9 16.1 0.3 0.0 0.6 0.6 13.9 0.3 0.5 1.8 1.5 0.1 3.7 0.0 34.6 3.2 0.2 0.0 1.4 15.2 8.5 7.4 13.3 0.0 0.0 16.7 0.0 4.7 5.5 0.0 25.7 1.3 18.7 8.9 0.3 2.4 0.0 63.6 0.5 2.0 0.3 1.0 8.0 12.2 3.2 0.0 31.9 0.3 17.4 1.0 139.7 2.1 2.6 0.0 18.0 2.5 0.1 0.1 1.0 0.1 1.1 6.6 5.1 10.5 6.1 8.9 0.3 0.0 14.2 5.1 2.2 0.6 0.0 ADAMTS8 "ADAM-TS8, FLJ41712, METH2" ENSG00000134917 "ADAM metallopeptidase with thrombospondin type 1 motif 8" Q9UP79 11 130404923-130428609 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.6" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 14.5;Endometrial stromal cells: 30.9;Glandular and luminal cells: 37.7;Skeletal myocytes: 26.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.5;HeLa: 1.3;HMC-1: 4.4;NTERA-2: 2.2;U-2 OS: 9.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066349 Approved "Secreted to extracellular matrix" NA NA 3600000 "Cluster 19: Lung - Lung function" "Cluster 9: U-2 OS - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA066349: AB_2685662" "unprognostic (4.76e-6)" "unprognostic (3.92e-2)" "unprognostic (6.13e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.41e-1)" "unprognostic (7.81e-2)" "unprognostic (3.09e-2)" "unprognostic (9.83e-2)" "unprognostic (1.09e-4)" "unprognostic (3.05e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (4.66e-3)" "unprognostic (4.03e-3)" "unprognostic (5.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-1)" 1.8 0.1 1.5 10.1 2.7 0.0 0.7 0.0 3.7 2.0 0.0 7.0 1.1 3.0 1.0 3.0 2.1 1.6 2.3 3.5 0.0 0.5 0.0 27.6 0.1 0.7 0.1 0.4 0.7 0.0 0.2 2.6 0.2 2.7 0.5 0.0 0.5 4.9 0.5 0.3 2.1 4.2 0.1 0.4 5.3 0.3 1.0 0.0 0.2 0.5 0.0 4.2 0.9 1.8 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 1.3 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.7 0.0 3.7 3.5 0.0 0.7 0.1 0.2 0.1 1.0 1.8 1.3 0.0 0.6 1.0 0.0 0.4 0.4 0.1 0.0 2.4 2.3 3.9 9.1 0.0 1.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 14.5 30.9 0.6 0.0 0.0 7.4 0.0 0.0 6.6 0.0 37.7 1.3 1.3 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.7 0.5 0.0 0.1 1.8 2.8 0.0 0.1 1.0 0.5 5.9 0.0 0.0 1.5 0.0 0.5 0.0 0.1 2.6 0.2 0.0 26.9 5.7 0.1 0.3 0.1 0.1 0.0 0.6 0.1 0.0 0.0 ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 41.2" "Cell type enhanced" "Detected in many" "Adipocytes: 166.3;Astrocytes: 84.2;Basal prostatic cells: 87.2;Endometrial stromal cells: 179.1;Endothelial cells: 221.0;Prostatic glandular cells: 115.7;Smooth muscle cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 23.6;RPTEC TERT1: 27.1;SH-SY5Y: 128.3;SuSa: 40.5;WM-115: 28.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028567, HPA028577, HPA028601" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" No NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Endoplasmic reticulum" "HPA028567: AB_10599275, HPA028577: AB_10600330, HPA028601: AB_2672694" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (4.83e-2)" "unprognostic (3.08e-1)" "unprognostic (1.37e-2)" "unprognostic (7.80e-3)" "unprognostic (5.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (7.67e-2)" "unprognostic (3.16e-3)" "unprognostic (1.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-3)" "unprognostic (5.00e-3)" 41.2 4.8 4.0 12.2 5.0 0.1 19.0 5.5 5.3 16.2 7.9 8.1 1.2 13.2 1.1 5.3 10.2 7.8 15.6 4.4 5.6 9.5 2.7 13.6 1.9 10.8 8.1 7.3 9.8 6.3 2.2 31.7 8.5 7.9 2.7 1.4 3.2 3.7 7.4 2.6 3.7 12.1 8.0 4.1 4.7 0.8 8.1 1.0 7.3 7.3 1.1 22.5 9.0 6.4 0.0 1.2 13.9 0.0 0.6 0.1 1.3 0.2 0.0 0.0 0.0 1.9 0.0 0.0 2.3 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.9 0.0 8.8 2.6 0.0 0.0 0.5 0.0 23.6 0.0 0.5 0.0 0.3 0.1 0.0 0.0 7.5 1.1 0.0 0.0 2.4 0.1 27.1 0.3 0.1 128.3 0.0 0.0 0.0 40.5 0.0 0.7 5.4 0.8 0.4 0.0 0.8 0.0 0.0 0.0 0.5 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.0 5.5 5.3 4.4 5.6 10.8 8.1 8.5 8.0 8.1 6.4 166.3 3.2 4.8 84.2 0.0 17.5 87.2 0.0 4.6 0.0 6.9 15.9 6.6 2.8 2.6 38.6 2.1 1.0 0.2 1.1 0.0 69.7 0.9 13.2 179.1 221.0 1.2 0.0 4.2 3.3 0.6 31.4 1.5 33.8 0.0 8.4 27.1 0.3 7.5 0.0 14.3 1.1 0.0 0.3 20.1 0.4 2.5 2.7 26.6 21.5 0.0 0.2 0.0 26.7 0.6 45.5 1.0 2.2 0.0 115.7 0.0 10.8 0.1 0.1 0.0 20.7 94.8 0.3 0.7 1.3 13.5 1.6 3.2 12.1 0.9 36.7 ADCY1 "AC1, DFNB44" ENSG00000164742 "Adenylate cyclase 1" Q08828 7 45574140-45723116 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, cAMP biosynthesis" "Calmodulin-binding, Lyase" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.7;liver: 19.2;retina: 53.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 521.3;Excitatory neurons: 147.2;Inhibitory neurons: 117.9;Rod photoreceptor cells: 174.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 22.2;SH-SY5Y: 25.5;SK-MEL-30: 30.1;WM-115: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018364, HPA068274" Uncertain Approved Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "CAB018364: AB_2223098, HPA068274: " "unprognostic (9.41e-3)" "unprognostic (7.30e-4)" "unprognostic (9.31e-2)" "unprognostic (2.98e-1)" "unprognostic (4.18e-2)" "unprognostic (3.07e-3)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (1.64e-3)" "unprognostic (2.89e-1)" "unprognostic (7.73e-3)" "unprognostic (1.54e-1)" "unprognostic (4.74e-6)" "unprognostic (2.49e-1)" "unprognostic (7.65e-3)" "unprognostic (2.87e-1)" "unprognostic (2.23e-1)" 1.9 1.8 13.7 0.3 22.4 0.0 4.7 15.4 33.7 5.3 0.0 0.4 0.2 1.8 0.5 0.6 2.0 0.6 2.9 31.9 0.0 1.9 19.2 0.6 0.4 1.2 0.9 0.9 3.3 1.9 2.6 0.4 1.1 2.8 0.4 53.0 0.3 1.2 7.7 0.4 0.3 0.9 0.0 1.7 1.1 2.8 4.0 0.3 2.4 8.5 0.3 0.8 1.3 24.5 0.8 5.9 2.1 3.2 4.1 0.1 4.0 0.2 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 5.8 1.9 3.8 0.3 0.1 10.7 2.7 0.0 0.0 0.6 0.0 0.2 0.1 4.9 2.8 0.5 22.2 0.0 0.1 8.6 0.3 7.0 0.3 7.1 0.0 0.0 8.3 5.1 0.0 0.0 0.0 11.7 0.0 5.7 13.4 25.5 2.1 0.0 30.1 3.1 2.0 3.5 0.0 0.6 4.2 0.5 3.6 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 22.4 15.4 33.7 31.9 0.0 1.2 0.9 1.1 0.0 4.0 24.5 3.5 0.0 0.0 30.7 0.3 0.3 0.6 0.0 0.0 43.8 10.6 5.7 11.4 2.8 0.0 0.0 521.3 0.1 0.3 0.5 1.9 0.0 2.9 1.0 23.1 10.8 31.2 0.0 147.2 0.9 0.2 4.2 0.0 0.7 0.0 0.2 15.7 52.3 0.3 42.1 117.9 1.0 2.0 3.2 0.4 0.7 1.8 0.2 3.6 17.8 0.0 13.8 0.0 63.3 4.0 0.5 0.1 7.5 0.1 2.6 0.0 0.4 0.0 174.4 0.0 2.3 8.8 0.5 6.8 0.1 0.1 0.0 0.6 0.6 0.6 0.3 ADGRB1 BAI1 ENSG00000181790 "Adhesion G protein-coupled receptor B1" O14514 8 142449430-142545009 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity, Myogenesis, Neurogenesis, Phagocytosis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 37.3" "Cell type enhanced" "Detected in some" "Astrocytes: 58.8;Excitatory neurons: 47.5;Horizontal cells: 126.2;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 70.9" "Cancer enriched" "Detected in many" 5 "glioma: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 12.1;MCF7: 4.6;NB-4: 6.1;RPMI-8226: 17.5;U-2 OS: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (9.57e-4)" "unprognostic (1.28e-1)" "unprognostic (3.87e-3)" "unprognostic (8.50e-3)" "unprognostic (9.98e-2)" "unprognostic (5.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.14e-2)" "unprognostic (2.76e-1)" "unprognostic (2.55e-1)" "unprognostic (6.48e-2)" "unprognostic (3.43e-1)" "unprognostic (7.30e-11)" "unprognostic (6.27e-2)" "unprognostic (7.42e-2)" "unprognostic (4.52e-3)" "unprognostic (3.29e-2)" 0.6 1.8 21.7 0.3 17.7 0.1 0.6 0.8 37.3 2.9 0.0 0.8 0.3 1.2 0.7 0.7 0.8 0.1 0.5 18.6 13.7 0.7 0.2 0.8 0.4 12.9 9.4 1.3 0.4 1.6 6.4 0.9 13.1 1.5 0.0 1.6 0.9 0.5 0.1 5.0 1.1 0.1 1.2 2.5 0.8 1.9 24.0 0.2 0.6 0.1 0.1 0.4 1.3 5.4 0.0 0.1 0.1 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.9 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 6.1 1.9 0.2 0.0 0.1 0.0 17.5 0.0 0.0 3.2 3.2 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.1 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 17.7 0.8 37.3 18.6 13.7 12.9 9.4 13.1 1.2 24.0 5.4 0.1 0.0 0.0 58.8 0.3 0.0 0.6 0.0 1.8 18.5 1.3 0.8 5.7 1.5 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.3 0.2 0.0 0.1 0.4 0.0 0.0 47.5 0.0 0.0 0.8 0.5 0.0 0.0 0.2 0.0 0.0 0.1 126.2 38.0 0.1 0.0 0.3 0.0 1.0 0.3 0.3 0.0 9.4 0.8 3.9 0.0 70.9 2.6 0.1 0.1 13.5 0.0 0.2 0.0 0.2 0.0 0.9 6.6 0.4 0.4 0.0 0.8 0.1 0.0 0.0 0.3 0.3 0.1 0.2 ADM AM ENSG00000148926 Adrenomedullin P35318 11 10305073-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 340.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 590.8;Extravillous trophoblasts: 1217.1;Syncytiotrophoblasts: 1084.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "neutrophil: 242.2" "Lineage enriched" "Detected in many" 18 "granulocytes: 242.2" "Cell line enhanced" "Detected in many" "ASC diff: 684.6;fHDF/TERT166: 357.4;HSkMC: 410.9;U-138 MG: 390.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016075, HPA068955" Approved "Secreted to blood" NA NA 31000 340000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016075: AB_628693, HPA068955: " "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (1.55e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (8.13e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.33e-4)" "unprognostic (9.70e-3)" "unprognostic (2.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.62e-2)" 340.2 29.9 12.9 32.2 18.3 43.9 195.9 28.1 15.2 162.1 17.9 60.6 8.0 20.3 3.1 84.6 71.0 30.0 153.3 10.6 15.5 123.8 90.5 157.6 17.1 19.7 18.0 33.1 24.6 23.5 43.3 102.8 16.5 26.8 11.4 16.7 52.7 1.6 79.3 169.8 49.5 7.6 16.8 34.5 55.5 4.9 21.6 4.1 52.7 14.3 3.5 85.1 224.3 18.6 35.4 29.2 33.8 9.8 684.6 306.7 51.8 263.6 263.9 260.5 175.7 142.4 43.9 0.1 11.7 357.4 136.9 51.0 9.5 40.6 191.9 0.7 13.9 1.1 16.1 18.0 88.0 1.6 1.1 410.9 34.7 30.8 44.6 89.9 60.4 0.5 0.4 0.7 64.3 1.2 0.2 10.6 65.7 8.4 13.6 1.0 1.1 54.5 16.7 48.6 1.1 3.2 101.0 23.7 0.6 36.4 31.4 0.3 17.9 390.0 5.5 233.2 37.9 2.7 29.5 10.5 112.0 0.2 117.0 0.0 7.0 0.0 0.0 7.7 0.0 0.3 0.0 0.0 2.4 0.0 0.0 0.1 242.2 0.0 13.6 0.0 0.3 1.9 12.9 18.3 28.1 15.2 10.6 15.5 19.7 18.0 16.5 16.8 21.6 18.6 347.7 9.6 12.3 17.0 14.2 192.1 590.8 194.4 182.1 2.7 28.0 46.9 104.6 18.6 136.2 3.7 8.4 134.6 9.1 266.7 15.6 135.7 0.5 80.8 58.1 99.1 67.5 4.0 0.4 30.5 1217.1 202.8 55.0 210.9 9.5 30.1 95.7 18.6 71.4 3.3 3.0 127.6 181.0 69.6 57.7 2.6 132.7 107.9 40.9 6.5 8.1 4.9 1.0 1.5 0.1 61.7 298.3 19.2 20.0 218.9 14.0 60.1 38.7 15.3 0.0 73.3 76.5 5.1 4.9 182.3 125.6 1084.8 14.7 8.1 55.5 224.5 ADNP "ADNP1, KIAA0784" ENSG00000101126 "Activity dependent neuroprotector homeobox" Q9H2P0 20 50888916-50931437 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006371 Supported Approved Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA006371: AB_1078105" "unprognostic (3.40e-2)" "unprognostic (6.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-1)" "unprognostic (6.68e-2)" "prognostic unfavorable (1.65e-5)" "unprognostic (1.73e-1)" "unprognostic (1.80e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (1.39e-2)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (3.63e-1)" "unprognostic (1.90e-2)" "unprognostic (1.08e-1)" 21.1 22.3 31.9 20.2 33.1 25.3 32.6 37.5 40.0 26.6 30.6 23.3 20.1 31.4 42.1 23.9 29.4 22.3 19.4 32.1 32.7 24.9 25.4 24.0 28.9 30.8 31.7 39.3 21.8 36.1 20.5 25.3 30.7 28.6 24.1 43.6 21.9 29.9 35.7 27.9 22.8 29.7 31.2 25.0 26.7 36.6 35.1 44.8 29.6 28.4 35.6 26.7 23.9 36.9 51.2 50.9 103.2 53.7 51.3 47.3 38.8 41.2 48.1 79.0 55.8 80.4 42.3 74.0 51.7 52.9 41.9 62.1 86.6 85.1 89.5 32.6 30.8 54.2 58.1 64.0 48.9 87.7 41.2 47.1 101.3 47.8 85.7 61.2 56.7 46.2 66.7 47.2 51.6 61.6 76.4 61.4 45.5 52.7 42.8 76.2 54.4 55.5 50.9 77.2 81.2 61.9 92.7 138.0 73.6 65.8 62.7 82.5 44.7 68.6 69.4 49.0 45.8 36.3 39.2 104.0 42.2 50.5 47.3 38.5 23.8 22.3 40.5 37.4 42.7 26.0 44.6 36.9 28.3 29.8 43.8 58.4 12.3 31.4 52.8 58.2 32.8 22.5 31.9 33.1 37.5 40.0 32.1 32.7 30.8 31.7 30.7 31.2 35.1 36.9 45.5 9.6 24.4 85.5 31.1 60.0 32.9 22.9 26.7 41.3 46.9 39.2 38.0 38.6 26.4 14.7 25.0 31.4 55.4 25.6 17.6 22.2 26.3 50.0 59.9 33.4 37.1 26.9 75.6 21.9 20.3 32.8 25.0 61.3 17.2 72.5 27.1 29.5 22.5 38.7 93.5 29.3 18.3 27.4 41.0 38.8 31.4 28.9 40.9 77.8 26.7 25.0 20.6 124.1 122.7 28.5 21.1 39.9 27.0 36.1 22.1 23.2 22.0 37.1 39.5 45.9 41.2 27.9 35.2 31.2 52.0 22.2 36.6 42.8 33.7 39.8 ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442357 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.6;brain: 101.4;lymphoid tissue: 54.1" "Group enriched" "Detected in some" 6 "B-cells: 5.8;monocytes: 10.9;Plasma cells: 11.8;T-cells: 3.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "basal ganglia: 101.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 39.3;Karpas-707: 52.8;RPMI-8226: 41.1;SK-BR-3: 74.0;U-266/70: 52.8;U-266/84: 74.4;U-698: 55.0" "Region enriched" "Detected in many" 9 "basal ganglia: 399.8" "Region enriched" "Detected in many" 50 "basal ganglia: 142.2" "CAB001943, HPA065566, HPA075997" Enhanced Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB001943: , HPA065566: , HPA075997: AB_2732298" "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" 3.4 5.4 12.3 13.5 101.4 40.6 2.5 10.8 19.2 4.0 8.0 4.1 6.6 2.9 1.6 2.0 3.7 3.0 13.5 11.6 10.0 17.5 14.5 14.6 20.5 10.2 10.4 3.9 2.3 0.2 6.7 1.8 10.4 5.5 1.0 2.1 3.2 1.7 2.5 1.6 7.0 0.9 9.9 15.2 4.0 3.1 19.9 54.1 4.3 1.4 10.4 5.3 3.4 9.7 0.5 0.9 1.0 0.3 0.4 0.3 1.0 0.7 23.2 1.3 2.4 4.5 0.3 39.3 2.6 0.7 2.4 1.0 2.4 0.0 0.0 4.7 6.6 0.7 0.2 5.6 0.4 0.8 18.7 0.2 0.2 7.2 0.0 0.5 8.2 5.8 0.3 52.8 0.0 0.7 14.0 4.2 1.6 5.0 0.1 0.6 1.7 41.1 0.1 0.3 3.9 21.6 1.1 74.0 0.3 1.1 0.8 3.7 0.5 2.2 3.7 0.5 0.4 52.8 74.4 55.0 11.5 13.6 0.3 9.6 2.1 11.6 20.0 6.5 46.9 21.9 37.4 39.2 2.6 38.3 51.5 42.4 32.6 6.3 23.1 2.9 54.0 27.1 12.3 101.4 10.8 19.2 11.6 10.0 10.2 10.4 10.4 9.9 19.9 9.7 0.0 0.0 0.5 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.5 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159973012 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 36.9;liver: 11.4;lymphoid tissue: 11.6" "Group enriched" "Detected in some" 7 "Excitatory neurons: 41.5;Inhibitory neurons: 32.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 36.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.9;HaCaT: 5.8;TIME: 9.8;U-2 OS: 7.9;U-251 MG: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA074416: AB_2686688" "unprognostic (4.93e-3)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.00e-5)" "prognostic unfavorable (6.98e-4)" "unprognostic (4.08e-3)" "unprognostic (1.67e-3)" "unprognostic (1.68e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.28e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.40e-6)" "unprognostic (5.24e-4)" "unprognostic (2.54e-1)" "prognostic favorable (3.19e-5)" "unprognostic (1.59e-2)" 4.2 1.8 3.4 0.3 16.1 0.0 1.9 0.0 7.9 0.4 0.0 0.7 0.4 0.9 1.4 0.3 3.0 0.5 2.0 6.0 3.4 3.9 11.4 4.0 1.2 0.0 36.9 2.9 0.4 0.5 0.6 0.3 6.3 0.6 0.3 0.5 0.3 0.7 0.7 0.9 1.4 0.4 0.0 11.6 0.7 0.2 4.5 0.1 1.5 0.7 0.3 0.4 0.6 5.2 0.4 4.5 0.3 0.0 1.9 0.8 0.1 0.5 0.1 0.5 0.2 0.0 3.8 0.0 11.9 3.4 4.4 5.8 0.0 0.5 0.3 0.0 0.2 0.0 1.7 0.0 4.1 0.0 0.0 2.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.7 0.0 3.8 0.0 0.4 0.0 0.0 0.3 0.3 1.7 0.1 0.0 9.8 0.1 7.9 0.0 6.6 0.0 0.0 0.0 2.9 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 16.1 0.0 7.9 6.0 3.4 0.0 36.9 6.3 0.0 4.5 5.2 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AFDN "AF-6, AF6, MLLT4" ENSG00000130396 "Afadin, adherens junction formation factor" P55196 6 167826922-167972023 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Alveolar cells type 1: 169.9;Breast glandular cells: 119.1;Endometrial ciliated cells: 194.3;Glandular and luminal cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868" Approved Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 37: B-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB013496: , HPA030212: AB_10599291, HPA030213: AB_10601340, HPA030214: AB_10601005, HPA030215: AB_10601556, HPA049868: AB_2680924" "prognostic unfavorable (7.43e-5)" "unprognostic (2.66e-3)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (4.12e-1)" "unprognostic (3.12e-2)" "unprognostic (4.12e-1)" "unprognostic (1.09e-3)" "unprognostic (1.75e-1)" "unprognostic (1.73e-2)" "unprognostic (5.56e-2)" "unprognostic (5.43e-3)" "unprognostic (1.59e-1)" "unprognostic (4.72e-2)" "unprognostic (5.68e-2)" 39.7 15.0 25.1 23.1 34.8 5.5 49.5 27.2 27.9 46.0 35.1 55.3 53.1 35.8 39.8 126.3 63.8 33.6 47.3 21.0 29.7 45.0 66.8 57.0 10.9 30.2 30.0 31.2 61.2 32.8 38.3 44.9 29.5 47.0 62.7 47.1 79.0 28.6 34.0 54.7 71.1 23.9 12.3 34.2 50.6 31.3 31.2 7.3 51.4 28.4 27.3 29.2 61.8 35.3 67.7 20.7 141.2 50.8 13.5 11.3 104.8 26.8 13.7 22.7 27.9 88.8 41.1 12.0 48.3 16.3 35.5 31.8 59.2 55.1 40.3 76.1 61.1 0.4 9.1 67.9 20.3 7.7 30.8 8.0 36.2 38.1 89.0 36.1 42.8 25.6 137.4 45.5 14.9 29.2 0.8 0.6 34.7 95.6 9.5 43.6 37.1 51.2 41.3 32.5 65.1 39.6 27.2 101.7 40.5 131.1 12.2 2.8 62.9 10.6 50.5 45.7 44.9 0.8 59.3 24.5 31.4 15.4 93.7 0.0 0.1 0.0 0.3 0.1 0.2 1.1 0.3 0.1 0.2 0.7 0.0 0.1 0.9 0.0 0.1 0.0 0.2 0.0 25.1 34.8 27.2 27.9 21.0 29.7 30.2 30.0 29.5 12.3 31.2 35.3 173.8 169.9 89.3 0.0 6.4 0.0 0.0 0.0 0.0 0.0 119.1 83.3 0.0 0.0 40.9 95.6 0.0 30.6 4.7 0.0 21.5 70.1 0.0 194.3 42.0 36.3 0.0 0.0 0.0 39.4 35.0 20.5 0.0 273.4 8.8 65.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 10.9 0.0 0.0 0.0 0.0 65.7 0.0 0.0 4.5 0.0 0.0 35.0 46.7 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 42.1 5.6 13.2 0.0 0.0 AFF1 "AF-4, AF4, MLLT2, PBM1" ENSG00000172493 "AF4/FMR2 family member 1" P51825 4 86935002-87141054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 225.2;Microglial cells: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069947 Approved Nucleoplasm,Mitochondria No No "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Mitochondria" "HPA069947: AB_2686219" "unprognostic (1.01e-1)" "unprognostic (7.56e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.55e-2)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" "unprognostic (6.09e-2)" "unprognostic (7.13e-2)" "unprognostic (1.24e-1)" "unprognostic (8.32e-3)" "unprognostic (5.86e-2)" "unprognostic (1.33e-2)" "unprognostic (4.41e-1)" "unprognostic (2.55e-1)" "unprognostic (2.71e-2)" 33.2 18.0 10.7 18.1 11.8 35.0 22.8 8.1 13.0 24.8 51.4 25.9 18.2 25.6 11.8 19.1 21.4 19.6 19.6 10.2 10.0 32.8 24.8 20.7 16.3 16.3 9.8 28.8 28.2 31.8 12.5 26.8 11.8 18.2 22.5 63.6 24.0 22.8 55.6 23.4 19.4 31.9 9.1 19.4 19.0 6.9 14.2 22.8 54.9 41.8 13.4 18.5 19.0 12.0 15.3 13.5 11.3 12.0 18.3 21.6 15.9 15.1 22.2 11.3 16.7 14.7 27.8 17.3 20.2 18.7 14.4 6.8 18.0 22.8 15.7 29.8 7.2 36.0 38.3 12.3 14.1 35.0 27.4 17.7 16.1 19.4 17.0 16.4 42.1 14.1 22.5 47.5 4.8 4.1 31.6 10.1 15.0 25.6 4.8 24.7 6.7 22.2 33.1 14.5 25.6 4.7 23.1 15.0 7.2 23.5 9.0 28.9 21.3 20.9 18.8 12.9 8.5 41.0 24.8 29.6 17.1 39.5 7.7 5.4 7.4 17.6 8.8 5.4 9.8 12.0 11.8 8.9 8.5 14.5 6.0 5.8 28.4 7.7 3.3 20.7 11.3 4.2 10.7 11.8 8.1 13.0 10.2 10.0 16.3 9.8 11.8 9.1 14.2 12.0 88.0 41.7 55.6 125.7 29.3 24.1 20.2 17.8 33.6 41.7 20.6 11.6 119.8 40.0 28.4 92.0 225.2 1.4 29.1 40.7 3.9 11.9 7.2 32.4 39.1 50.2 32.3 54.5 69.2 12.6 4.2 36.3 42.8 46.2 25.2 40.3 65.0 34.2 13.0 18.5 47.5 35.8 16.2 41.7 32.8 9.3 29.2 34.8 23.2 202.4 16.5 21.4 16.5 74.4 84.0 13.1 31.4 28.6 53.9 21.9 29.8 50.3 36.0 147.2 26.3 41.9 31.2 3.8 11.3 45.3 31.7 32.8 26.4 13.3 29.0 15.8 AFF3 "LAF4, MLLT2-like" ENSG00000144218 "AF4/FMR2 family member 3" P51826 2 99545419-100192428 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 154.9;Excitatory neurons: 491.3;Inhibitory neurons: 300.7;Oligodendrocyte precursor cells: 211.6" "Group enriched" "Detected in many" 5 "breast cancer: 11.4;prostate cancer: 7.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory B-cell: 31.0;naive B-cell: 44.2;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 17 "B-cells: 44.2;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "Daudi: 51.1;U-698: 56.5" "Low region specificity" "Detected in all" "HPA044512, HPA053379" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA044512: AB_10795984, HPA053379: AB_2682133" "unprognostic (1.05e-2)" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.88e-3)" "unprognostic (1.02e-1)" "unprognostic (4.98e-5)" "unprognostic (1.11e-3)" "unprognostic (3.04e-2)" "unprognostic (8.75e-2)" "unprognostic (3.07e-1)" "unprognostic (1.95e-3)" "unprognostic (7.57e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (6.40e-3)" "unprognostic (6.79e-2)" "unprognostic (3.69e-2)" "unprognostic (7.87e-3)" 3.3 1.6 3.1 6.2 3.9 11.2 11.6 17.4 13.2 3.5 0.0 5.1 1.1 7.7 0.8 3.5 4.5 2.2 4.3 9.7 5.0 1.4 1.7 6.5 14.2 2.2 0.0 6.3 0.4 0.1 4.4 6.2 1.8 16.2 2.2 4.2 1.9 2.5 0.7 0.9 6.0 5.9 0.0 7.3 4.6 5.4 0.0 7.7 1.2 0.7 12.2 6.7 2.2 9.8 0.2 0.0 18.0 6.4 0.0 0.6 0.0 2.8 0.7 5.6 1.9 0.0 0.0 51.1 0.1 3.8 12.4 0.2 0.5 0.0 4.0 14.3 6.3 0.0 0.0 0.0 0.4 0.2 12.4 0.8 0.0 12.8 0.2 13.8 0.0 2.2 0.3 0.1 0.0 0.1 4.3 0.3 1.8 0.0 3.2 7.5 0.0 0.3 0.0 0.0 17.4 6.5 0.0 0.3 11.0 1.5 17.9 16.5 6.7 19.1 3.4 0.5 2.9 0.8 0.1 56.5 15.9 1.5 2.0 0.6 0.5 0.1 0.0 0.5 0.3 31.0 0.2 0.0 5.1 44.2 1.9 0.0 0.0 1.0 0.4 23.9 0.0 0.8 3.1 3.9 17.4 13.2 9.7 5.0 2.2 0.0 1.8 0.0 0.0 9.8 1.2 6.4 40.9 41.8 154.9 1.8 0.4 0.0 1.8 21.8 78.9 37.7 11.1 0.0 3.7 0.0 12.5 0.4 32.8 0.1 0.0 0.0 33.9 0.9 19.8 6.0 22.9 3.4 491.3 0.0 0.2 13.5 1.1 1.1 0.0 31.6 0.7 1.2 1.8 47.1 300.7 0.5 0.0 9.2 18.2 38.5 10.8 16.5 14.2 66.5 5.2 6.8 0.0 211.6 46.7 0.0 0.1 21.1 0.8 14.3 0.1 1.9 0.0 1.7 0.0 1.1 8.5 10.5 9.8 0.0 1.3 0.1 6.1 5.7 0.6 0.3 AFF4 "AF5Q31, MCEF" ENSG00000072364 "AF4/FMR2 family member 4" Q9UHB7 5 132875395-132963634 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023690, HPA029634" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA023690: AB_1844633, HPA029634: AB_2673129" "unprognostic (3.24e-2)" "unprognostic (1.86e-2)" "unprognostic (6.17e-3)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (2.56e-2)" "unprognostic (7.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.13e-2)" "unprognostic (4.94e-2)" "unprognostic (3.52e-1)" "unprognostic (1.16e-2)" "unprognostic (2.77e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.69e-1)" 21.4 28.2 10.9 16.9 13.3 43.4 22.8 20.2 15.3 20.3 9.9 18.5 14.4 26.7 18.2 26.8 16.4 26.0 16.5 11.3 18.7 24.3 21.1 19.7 15.4 11.5 16.1 28.9 24.9 36.3 19.5 20.5 10.6 25.1 17.6 47.3 19.1 21.3 25.4 18.5 15.0 23.6 7.8 16.8 25.1 18.0 19.0 19.0 33.2 25.6 17.1 23.1 19.3 15.6 42.5 33.5 45.2 50.3 34.1 40.9 35.3 44.8 47.9 40.4 51.2 49.8 27.2 21.5 51.7 59.2 49.0 20.8 36.8 55.5 67.3 15.4 23.7 26.6 44.6 17.8 43.6 9.4 26.5 48.2 36.2 70.2 70.7 43.5 39.4 19.2 19.4 17.7 51.2 16.0 26.1 10.0 17.4 12.6 13.6 17.3 44.1 8.1 35.0 58.8 35.2 37.0 50.9 12.3 50.4 62.0 26.2 15.0 55.9 48.3 40.8 43.0 48.2 24.3 45.3 19.3 45.2 17.2 33.7 13.0 1.8 3.2 4.0 1.5 3.0 6.2 3.7 2.8 2.2 6.3 3.8 3.3 4.1 3.0 4.1 4.1 1.9 1.3 10.9 13.3 20.2 15.3 11.3 18.7 11.5 16.1 10.6 7.8 19.0 15.6 134.3 80.1 43.9 62.3 98.7 79.7 79.8 52.0 140.0 74.8 94.1 76.7 65.2 57.2 70.8 58.8 158.4 36.4 75.9 69.9 7.9 51.1 244.1 136.4 147.8 79.3 97.6 29.2 99.5 46.2 47.8 98.0 197.2 229.0 43.1 222.1 54.3 25.2 41.9 79.1 85.1 59.1 50.8 62.3 123.7 200.5 69.3 100.9 69.4 60.9 41.6 61.9 39.1 73.9 106.0 75.8 65.5 67.4 93.0 97.3 56.1 35.7 53.2 135.1 78.9 126.5 103.8 34.2 21.5 130.6 86.5 69.9 68.9 89.6 47.2 120.0 AFP "FETA, HPAFP" ENSG00000081051 "Alpha fetoprotein" P02771 4 73431138-73456174 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 3.7" "Group enriched" "Detected in some" 10 "Hepatocytes: 107.5;Proximal tubular cells: 101.6" "Cancer enriched" "Detected in some" 4 "liver cancer: 208.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 192 "Hep G2: 2165.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010607, HPA023600, CAB024283, CAB025339" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 3010000 150000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "CAB024283: AB_2650473, CAB025339: , HPA010607: AB_1078141, HPA023600: AB_1844769" "unprognostic (4.69e-1)" "unprognostic (1.87e-1)" "unprognostic (3.34e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-3)" "unprognostic (2.95e-2)" "unprognostic (3.35e-1)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-6)" "unprognostic (1.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 1.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 9.7 5.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 7.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 2.7 2.8 0.3 0.0 0.1 0.0 0.1 2.5 107.5 2.3 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 101.6 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 1.5 0.2 0.1 0.2 0.0 AGER "RAGE, SCARJ1" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lung: 728.3" "Cell type enriched" "Detected in many" 22 "Alveolar cells type 1: 2394.2" "Cancer enhanced" "Detected in all" "lung cancer: 27.2;thyroid cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.5;JURKAT: 3.0;RPTEC TERT1: 2.2;U-266/70: 2.4;U-266/84: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" NA NA 5360000 100000 "Cluster 19: Lung - Lung function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: AB_2258049, HPA064436: AB_2685264, HPA069474: " "unprognostic (9.37e-2)" "unprognostic (3.70e-1)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.01e-7)" "unprognostic (3.57e-1)" "unprognostic (3.70e-2)" "unprognostic (4.44e-2)" "prognostic favorable (2.74e-6)" 2.2 1.7 0.1 1.1 0.1 0.5 1.6 0.1 0.4 4.4 0.2 3.9 0.6 2.5 1.9 2.1 4.5 0.1 2.7 0.2 0.1 6.4 2.7 728.3 0.6 0.2 0.1 4.8 1.7 0.0 5.0 0.4 0.2 4.9 0.8 0.4 1.6 0.0 1.0 2.0 3.2 0.1 0.1 7.0 2.0 2.2 0.2 0.8 39.2 0.1 0.5 2.9 3.2 0.3 0.1 0.0 0.0 0.3 0.1 0.9 1.5 0.0 0.1 0.0 0.1 0.0 0.2 0.1 1.0 0.2 0.0 1.0 0.1 0.3 0.2 0.2 2.5 0.7 0.0 0.0 0.0 0.3 1.1 0.0 0.1 0.0 0.1 0.2 0.1 3.0 0.0 0.3 0.1 1.3 0.1 0.9 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.5 0.0 0.1 0.0 0.6 0.8 0.1 2.4 2.0 0.9 1.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 5.4 2394.2 107.9 5.9 4.9 0.9 1.5 2.0 2.8 5.1 1.5 2.9 3.0 4.3 20.9 1.8 0.0 1.1 2.7 1.1 0.0 1.5 0.4 1.1 2.6 4.1 0.0 4.4 0.5 1.0 0.9 3.0 1.5 1.9 17.7 3.1 2.9 2.0 1.3 6.7 0.6 1.3 0.0 5.3 6.5 1.2 1.8 5.3 1.8 4.7 4.8 4.6 2.1 2.5 1.3 1.1 2.7 1.2 3.3 2.6 0.8 0.3 5.6 3.4 6.6 1.2 2.6 0.1 1.2 1.6 1.8 2.2 6.2 1.7 1.2 0.9 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.3;Basal respiratory cells: 83.8;Horizontal cells: 60.6;Ionocytes: 61.1;Pancreatic endocrine cells: 68.2;Respiratory ciliated cells: 66.8;Squamous epithelial cells: 63.7;Suprabasal keratinocytes: 164.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 135.1;HBEC3-KT: 124.9;hTCEpi: 308.7;hTERT-HME1: 130.3;TIME: 138.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" 30.4 2.3 9.8 2.4 9.9 0.0 16.4 9.3 15.9 84.5 4.6 105.3 1.4 64.3 2.9 114.1 29.2 5.1 4.5 9.7 16.0 3.5 6.2 5.1 0.1 38.1 15.3 3.5 1.6 0.7 3.4 1.8 40.8 18.6 8.6 19.0 24.0 28.6 3.6 305.9 20.2 31.6 12.4 0.9 25.2 7.7 18.1 0.4 2.8 4.5 4.7 49.4 86.6 18.5 2.9 107.6 0.1 6.0 120.0 135.1 0.2 10.5 22.3 3.8 1.9 0.3 38.9 0.1 14.5 82.9 85.3 62.9 0.3 124.9 1.7 0.0 0.4 0.0 67.5 0.5 11.0 0.0 3.8 17.6 308.7 12.1 130.3 52.3 54.7 0.0 0.0 0.2 62.8 8.0 0.0 0.0 0.3 9.5 42.9 0.3 5.7 0.1 84.4 0.0 0.6 0.6 46.2 0.1 2.3 2.8 6.0 0.0 138.4 29.3 17.9 33.8 9.9 0.0 0.0 0.0 88.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.8 9.9 9.3 15.9 9.7 16.0 38.1 15.3 40.8 12.4 18.1 18.5 3.8 12.8 1.1 0.3 0.0 114.3 4.9 83.8 13.1 8.9 2.2 1.3 1.5 0.0 38.2 1.8 2.1 0.2 0.3 0.4 0.0 11.9 24.2 16.0 10.5 13.0 0.0 0.0 8.2 8.7 0.5 31.9 0.0 18.9 17.1 0.1 3.6 2.1 1.0 60.6 5.1 0.0 61.1 0.3 12.7 3.1 0.6 0.7 32.0 3.7 0.0 3.2 0.0 1.5 3.3 68.2 0.0 0.4 0.0 4.5 0.0 0.3 66.8 13.9 0.0 13.1 8.6 0.4 4.3 63.7 164.7 0.1 0.9 0.1 0.2 6.2 AHR bHLHe76 ENSG00000106546 "Aryl hydrocarbon receptor" P35869 7 16916359-17346152 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Cancer-related genes, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 262.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTCEpi: 71.0;hTERT-HME1: 73.8;OE19: 61.2;RT4: 63.2" "CAB005072, HPA029722, HPA029723" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoplasm "CAB005072: AB_633731, HPA029722: AB_10599189, HPA029723: AB_10599025" "unprognostic (1.29e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-2)" "unprognostic (7.28e-2)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-1)" "unprognostic (4.32e-2)" "unprognostic (9.98e-2)" "unprognostic (1.24e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-2)" "unprognostic (9.45e-2)" 22.3 15.0 1.4 25.8 2.7 44.1 19.5 1.4 2.8 14.5 2.3 13.7 16.4 8.8 7.0 17.4 10.5 33.7 9.5 1.9 1.3 7.1 45.0 37.6 15.4 5.4 1.9 6.9 5.8 6.6 3.0 17.7 3.9 11.0 16.3 4.0 10.5 11.2 2.2 22.0 14.5 15.2 2.8 18.7 25.2 2.9 2.7 9.7 12.7 6.5 19.8 49.5 15.0 5.8 8.2 6.6 2.6 0.0 19.2 13.1 1.2 16.5 23.9 7.5 10.8 8.2 17.5 0.0 5.0 24.4 29.7 21.8 1.6 15.1 19.7 0.4 3.6 4.8 8.1 7.3 35.5 8.1 11.5 18.1 71.0 28.8 73.8 33.8 25.3 0.0 0.7 0.2 34.3 4.2 0.0 12.6 2.1 61.2 10.3 0.0 0.0 0.3 23.5 63.2 2.4 0.0 12.4 13.0 12.5 19.0 9.4 2.7 4.3 3.1 0.1 40.7 0.0 3.3 0.1 0.0 51.6 30.6 51.9 0.8 5.6 4.2 0.5 2.6 0.7 0.6 1.7 1.0 6.9 0.7 0.9 0.7 0.6 2.1 1.0 1.6 2.1 1.7 1.4 2.7 1.4 2.8 1.9 1.3 5.4 1.9 3.9 2.8 2.7 5.8 78.3 150.6 76.2 1.6 15.2 75.3 47.6 67.9 104.2 37.0 23.4 30.0 14.7 34.3 84.9 7.3 8.4 3.3 13.6 23.9 0.0 19.3 6.2 39.1 8.4 78.1 5.4 8.6 18.0 15.7 1.8 57.0 56.1 78.8 133.1 0.6 52.1 48.3 24.4 43.7 39.2 12.9 30.5 88.4 262.6 3.2 3.7 107.1 71.2 8.4 70.1 0.9 5.2 1.5 40.6 33.3 19.8 2.6 16.7 48.6 9.9 6.8 51.3 6.1 6.6 14.8 37.8 2.8 2.2 38.3 89.2 21.5 54.7 3.3 19.3 116.1 AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186613060-186621318 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4302 "liver: 5817.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 1242.5" "Cancer enriched" "Detected in some" 284 "liver cancer: 1231.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 78 "Hep G2: 2287.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 864000000000 110000000000 "Cluster 48: NK-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus" "CAB026209: , HPA001524: AB_1078851, HPA001525: AB_1078849" "unprognostic (6.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.03e-2)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (5.27e-2)" "unprognostic (8.64e-2)" "unprognostic (3.99e-7)" "unprognostic (5.21e-2)" "unprognostic (5.21e-2)" "unprognostic (1.04e-1)" 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 1.3 5817.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.7 0.7 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.9 1.0 2287.3 0.0 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 3.5 0.0 0.0 1.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 1.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.2 0.0 0.1 3.9 0.2 4.3 0.2 0.1 0.9 0.0 32.0 0.6 0.6 2.4 0.1 0.0 0.1 0.0 0.0 28.2 1242.5 1.3 0.0 0.1 0.0 0.0 32.4 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.0 0.0 0.0 0.1 AJUBA "JUB, MGC15563" ENSG00000129474 "Ajuba LIM protein" Q96IF1 14 22971177-22982551 "Cancer-related genes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 61.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 47.5;Basal squamous epithelial cells: 35.3;Pancreatic endocrine cells: 33.8;Prostatic glandular cells: 34.2;Sertoli cells: 32.9;Suprabasal keratinocytes: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 217.0;hTCEpi: 222.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006171 Approved Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Golgi apparatus" "HPA006171: AB_1852044" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (2.39e-1)" "unprognostic (1.24e-3)" "unprognostic (9.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-3)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.47e-1)" "unprognostic (3.19e-3)" "unprognostic (2.94e-1)" "unprognostic (2.68e-1)" "unprognostic (9.35e-3)" "unprognostic (2.07e-1)" 4.8 3.0 2.3 1.4 1.8 0.5 6.7 2.0 2.2 14.4 9.2 3.2 1.5 12.1 8.5 18.3 7.5 4.9 6.3 2.2 1.5 17.7 43.4 15.2 2.6 2.5 2.1 12.2 11.6 7.2 2.0 19.3 1.6 10.6 2.5 3.7 8.2 15.9 1.9 61.7 1.9 8.4 2.2 3.8 4.2 5.5 1.9 8.2 10.9 2.3 5.5 7.6 15.5 2.7 46.9 54.1 71.0 27.6 6.8 12.2 57.4 44.9 58.5 102.6 91.4 116.0 47.3 1.2 45.5 92.9 70.8 146.2 54.9 217.0 124.6 4.5 5.0 3.5 90.8 131.4 78.9 4.9 3.1 38.9 222.3 42.9 164.3 72.7 40.0 8.3 1.9 2.8 96.2 37.3 4.5 5.7 4.5 86.6 73.9 12.7 59.0 1.2 103.9 71.3 0.2 6.2 135.5 39.4 8.8 57.4 55.3 4.5 36.1 44.2 88.4 7.3 43.6 0.4 1.3 0.5 7.0 4.2 20.6 0.7 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.2 0.5 0.5 0.2 0.2 0.0 0.1 2.3 1.8 2.0 2.2 2.2 1.5 2.5 2.1 1.6 2.2 1.9 2.7 2.1 19.2 6.4 0.7 0.0 47.5 13.0 27.6 35.3 0.1 3.7 9.7 4.5 20.0 10.2 7.3 0.0 10.0 0.1 0.3 5.9 14.3 5.8 13.0 2.5 4.0 0.0 0.0 0.0 14.9 9.8 3.4 0.0 4.4 0.0 12.8 2.5 17.1 1.7 0.0 0.0 0.4 2.0 0.0 2.2 5.0 3.7 0.6 3.6 0.0 0.0 8.1 0.0 0.5 0.0 33.8 0.1 0.7 1.2 34.2 0.3 21.0 8.3 0.2 32.9 2.7 14.0 7.0 2.7 14.2 49.6 4.0 0.5 1.6 0.8 18.0 AK9 "AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954" ENSG00000155085 "Adenylate kinase 9" Q5TCS8 6 109492856-109691217 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 76.3;Respiratory ciliated cells: 152.0;Spermatocytes: 174.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 3.6" "HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear membrane" "HPA030804: AB_2673617, HPA030805: AB_2673618, HPA031779: AB_10603674, HPA031781: AB_2674044, HPA036324: AB_2675060, HPA036711: AB_2675265" "unprognostic (9.68e-3)" "unprognostic (2.15e-1)" "unprognostic (1.66e-2)" "unprognostic (2.36e-2)" "unprognostic (3.42e-1)" "unprognostic (7.28e-2)" "unprognostic (1.41e-3)" "unprognostic (6.76e-3)" "unprognostic (1.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-4)" "unprognostic (2.58e-1)" "unprognostic (2.98e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (8.39e-2)" "unprognostic (5.56e-2)" 3.5 3.1 8.1 3.3 9.9 3.7 4.8 13.5 17.2 3.5 10.9 4.6 3.6 4.3 7.6 4.3 7.9 3.5 4.9 6.4 11.0 5.3 3.1 4.1 4.2 8.8 10.7 3.6 3.4 9.2 7.7 3.1 9.5 3.9 4.5 14.1 5.1 3.9 4.8 3.9 3.6 3.9 10.7 4.0 4.5 16.6 8.7 7.6 6.9 3.5 3.6 3.4 3.2 13.4 2.3 1.6 6.6 11.5 6.1 3.7 4.8 3.5 4.3 3.6 4.9 2.6 4.6 4.9 1.7 3.4 7.9 3.7 1.9 3.9 7.6 10.2 4.0 3.8 3.8 2.6 4.8 4.4 2.3 3.1 7.3 6.6 8.6 8.8 4.2 7.2 3.6 4.0 2.7 4.7 4.1 3.2 1.5 5.1 2.5 5.5 3.7 4.7 5.0 4.3 7.8 6.4 4.2 3.9 5.9 3.7 5.1 5.8 5.2 3.1 2.2 5.1 2.3 2.0 1.8 2.8 6.8 5.9 2.0 17.1 2.8 7.1 5.1 1.5 4.4 13.1 4.9 6.2 2.1 10.8 6.2 5.4 5.6 5.6 4.8 3.1 3.9 1.6 8.1 9.9 13.5 17.2 6.4 11.0 8.8 10.7 9.5 10.7 8.7 13.4 13.3 28.9 17.2 21.2 13.6 2.7 7.7 14.7 3.4 18.3 10.4 6.7 18.9 5.7 19.9 9.2 14.6 3.4 8.6 13.1 0.0 9.1 70.9 76.3 5.4 10.0 19.8 4.2 34.8 4.5 1.5 6.0 12.2 7.3 22.1 10.6 8.9 2.1 3.6 20.2 37.0 15.5 14.2 5.3 3.9 41.7 7.5 5.6 5.4 25.3 5.0 12.6 18.6 22.6 46.9 7.4 8.9 6.4 5.5 5.6 22.9 6.8 152.0 50.7 26.3 9.1 6.9 174.3 34.1 4.0 2.6 5.6 10.3 4.7 11.4 7.9 AKAP12 "AKAP250, SSeCKS" ENSG00000131016 "A-kinase anchoring protein 12" Q02952 6 151239967-151358559 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 352.6;Endothelial cells: 278.4;Fibroblasts: 270.0;Muller glia cells: 583.0;Pancreatic endocrine cells: 322.1;Spermatocytes: 325.4" "Cancer enhanced" "Detected in all" "testis cancer: 39.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 235 "basophil: 37.2" "Lineage enriched" "Detected in single" 235 "granulocytes: 37.2" "Cell line enhanced" "Detected in many" "REH: 193.0;TIME: 188.2;U-251 MG: 202.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006344, CAB026379, HPA056230" Enhanced Enhanced "Plasma membrane,Cytosol" No No 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB026379: , HPA006344: AB_1078118, HPA056230: AB_2683073" "unprognostic (6.66e-2)" "unprognostic (1.51e-1)" "unprognostic (9.90e-3)" "prognostic unfavorable (7.08e-4)" "unprognostic (2.61e-2)" "unprognostic (8.88e-2)" "unprognostic (5.05e-2)" "prognostic unfavorable (6.34e-5)" "unprognostic (1.34e-1)" "unprognostic (8.26e-3)" "unprognostic (2.59e-1)" "unprognostic (4.72e-2)" "unprognostic (4.51e-3)" "unprognostic (1.10e-3)" "unprognostic (3.51e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-2)" 105.6 16.0 13.8 17.1 16.6 2.2 59.7 99.7 57.5 19.8 4.5 60.1 8.6 31.1 9.3 18.6 31.2 31.5 51.8 14.7 66.8 35.8 30.6 44.3 6.9 67.0 35.3 87.8 10.8 1.6 23.3 38.3 74.7 23.1 13.2 109.4 6.5 20.8 11.9 9.4 24.9 42.9 10.9 14.3 25.6 100.0 39.4 5.9 22.1 14.5 3.4 33.0 21.2 24.3 7.8 37.8 53.2 0.1 98.2 145.9 18.8 43.9 23.7 19.3 19.4 0.9 141.6 0.0 17.1 33.2 160.4 1.0 102.2 32.5 17.2 50.2 37.6 0.6 40.8 35.6 10.9 0.0 9.6 104.0 0.0 81.9 4.3 25.4 127.8 0.6 9.8 0.9 70.7 0.5 0.3 0.1 33.3 0.1 43.9 193.0 2.3 0.2 110.2 6.3 37.9 22.0 14.1 0.5 24.9 74.6 2.8 0.5 188.2 2.6 34.0 110.4 202.9 0.4 0.1 0.2 63.2 0.1 37.4 37.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 16.6 99.7 57.5 14.7 66.8 67.0 35.3 74.7 10.9 39.4 24.3 352.6 12.8 16.2 34.3 6.8 19.6 19.6 63.2 1.2 14.5 1.2 3.9 12.1 5.7 31.1 51.5 2.1 2.4 0.9 1.2 1.9 107.0 101.4 14.2 195.4 278.4 1.8 3.2 75.8 6.7 10.1 270.0 3.6 31.6 64.2 14.7 194.5 4.8 26.9 0.0 33.3 0.7 4.1 15.7 45.4 116.3 39.7 13.9 58.7 37.5 0.6 583.0 1.0 59.8 5.1 322.1 1.1 110.6 6.7 49.5 0.0 89.4 6.0 31.0 98.6 208.3 243.0 325.4 33.0 1.6 11.4 10.0 5.1 9.3 2.5 105.3 AKAP9 "AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO" ENSG00000127914 "A-kinase anchoring protein 9" Q99996 7 91940840-92110673 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 2230.9;Rod photoreceptor cells: 1279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008548, CAB012909, HPA026109" Supported Enhanced "Golgi apparatus,Vesicles,Centrosome" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Vesicles, Centrosome" "CAB012909: AB_2533235, HPA008548: AB_1078121, HPA026109: AB_1844688" "unprognostic (9.57e-2)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (5.97e-3)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "unprognostic (4.75e-2)" "unprognostic (1.31e-2)" "unprognostic (1.28e-1)" "unprognostic (6.59e-2)" "unprognostic (7.59e-2)" "unprognostic (6.32e-2)" "prognostic favorable (2.10e-6)" "unprognostic (8.89e-2)" "unprognostic (1.73e-1)" "unprognostic (7.77e-2)" "unprognostic (3.96e-2)" 7.1 8.3 8.6 6.2 9.0 8.6 11.0 15.3 14.1 6.5 15.5 16.0 16.5 6.4 3.9 7.9 8.4 10.4 6.5 8.6 11.0 13.2 16.2 7.8 5.8 8.8 9.6 11.9 9.5 12.7 8.6 5.4 9.0 7.5 14.6 31.4 9.6 3.8 16.2 6.8 18.6 4.0 7.7 5.0 9.4 4.1 11.9 9.3 9.3 10.0 5.3 5.5 7.2 9.7 11.7 8.1 9.6 5.8 11.6 11.3 6.2 8.7 6.3 4.9 5.9 10.3 8.0 9.2 12.5 7.3 7.5 8.3 10.5 5.6 9.2 9.8 8.2 10.9 11.6 7.3 4.0 18.5 9.6 6.2 6.2 9.1 8.8 7.7 10.3 10.6 19.3 13.0 7.4 14.1 10.4 7.0 8.3 6.5 8.4 7.6 18.2 6.2 4.9 11.5 13.3 11.0 19.0 16.9 10.1 11.1 5.1 9.8 17.5 9.5 11.2 14.5 12.6 7.3 13.0 13.6 6.2 7.8 9.4 1.1 0.6 0.9 1.3 0.6 0.9 1.9 1.1 1.1 0.4 1.6 1.2 1.0 0.7 1.2 0.6 3.2 1.0 0.2 8.6 9.0 15.3 14.1 8.6 11.0 8.8 9.6 9.0 7.7 11.9 9.7 123.3 525.6 357.0 141.3 143.3 103.5 126.5 112.6 170.8 273.5 165.4 150.9 253.2 297.4 208.4 176.6 2230.9 141.4 201.5 293.4 101.8 131.0 22.5 392.3 157.7 115.9 185.1 129.4 142.6 92.6 81.9 123.5 152.9 185.0 136.6 386.1 98.2 153.5 57.2 360.1 182.6 350.8 136.3 78.3 88.4 17.5 173.4 101.6 58.7 115.2 121.5 155.7 119.4 169.9 187.1 102.4 218.9 135.8 193.5 91.4 298.5 47.2 506.3 1279.6 138.1 206.1 116.1 83.0 129.0 87.3 111.8 333.8 145.7 135.8 171.4 97.6 AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442356-134459284 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "adrenal gland: 3039.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 649.2;Cytotrophoblasts: 1105.1;Extravillous trophoblasts: 1284.9;Ionocytes: 697.8;Syncytiotrophoblasts: 2022.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 1667.3;BJ hTERT+: 3096.2;RPTEC TERT1: 1447.8;U-87 MG: 1343.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol No No 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: AB_10601563, HPA052751: AB_2681935" "unprognostic (2.76e-2)" "unprognostic (2.84e-2)" "unprognostic (2.02e-2)" "unprognostic (1.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.26e-1)" "unprognostic (4.18e-2)" "unprognostic (5.09e-2)" "unprognostic (2.51e-3)" "unprognostic (2.47e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.44e-5)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.00e-4)" 65.1 3039.1 83.1 38.4 89.3 21.9 52.3 91.8 97.4 41.4 80.9 40.1 20.5 42.4 44.0 28.2 38.7 40.2 208.2 84.1 92.5 218.0 19.3 55.0 74.6 101.6 96.9 60.5 34.4 111.2 76.5 203.7 104.9 34.4 30.9 36.5 41.9 332.7 330.0 26.6 50.8 39.6 91.4 62.8 51.4 44.9 88.7 54.9 44.3 396.9 62.5 67.3 35.0 101.4 184.2 1667.3 186.5 261.4 785.9 212.3 494.6 177.2 3096.2 259.3 335.0 75.8 170.6 0.0 79.2 301.5 1143.3 78.6 204.0 175.3 206.6 65.2 168.2 93.4 225.0 230.1 1117.9 0.1 0.8 196.9 133.4 367.6 98.3 252.8 370.3 181.1 0.1 62.4 292.4 3.5 283.3 131.0 309.2 13.9 1.8 292.9 116.5 138.8 1447.8 915.5 137.1 301.6 1261.5 1.5 134.3 121.3 0.6 140.6 289.6 254.5 116.0 22.7 195.6 168.2 196.9 470.0 1343.5 0.7 153.0 125.7 106.4 5.6 147.6 72.3 135.2 133.0 124.7 144.5 145.3 121.7 162.9 156.7 8.5 119.7 39.2 20.4 94.9 230.2 83.1 89.3 91.8 97.4 84.1 92.5 101.6 96.9 104.9 91.4 88.7 101.4 34.1 12.8 19.4 9.1 50.3 20.6 55.3 66.1 20.5 36.2 11.7 27.9 202.4 25.8 26.4 649.2 8.4 1105.1 35.1 2.3 164.4 112.7 5.0 6.1 20.9 50.9 31.0 20.2 10.5 41.5 1284.9 100.3 20.4 5.9 53.8 59.8 82.1 2.6 394.1 72.3 18.7 15.1 697.8 172.8 53.9 14.5 79.2 127.7 30.2 14.0 76.3 49.3 66.9 5.5 12.4 51.0 4.5 77.5 72.6 25.6 0.3 60.2 24.9 24.1 59.2 98.9 54.5 22.6 100.2 10.5 11.6 2022.4 49.9 70.5 6.7 54.2 AKT1 "AKT, PKB, PRKBA, RAC, RAC-alpha" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 61.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 61.5" "Cell line enhanced" "Detected in all" "MCF7: 558.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002891, CAB003765" Supported Supported Nucleoplasm,Microtubules NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm Microtubules "CAB003765: AB_562035, HPA002891: AB_1078123" "unprognostic (3.30e-2)" "unprognostic (4.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (9.17e-3)" "unprognostic (1.55e-3)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "prognostic favorable (4.83e-4)" "unprognostic (3.58e-2)" "unprognostic (1.90e-2)" "prognostic favorable (2.12e-4)" "unprognostic (7.14e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" 71.5 102.7 45.9 57.7 45.5 51.2 61.2 43.7 53.2 52.0 50.4 85.0 50.8 59.5 23.2 70.7 53.7 50.0 105.9 45.2 44.3 54.3 97.3 69.2 51.9 50.5 45.7 43.7 94.3 53.0 35.9 55.4 45.0 67.2 39.6 25.1 67.7 73.0 58.1 45.0 53.3 63.4 47.4 63.7 77.8 23.9 48.0 52.4 52.3 64.9 40.3 72.6 48.4 43.3 77.3 150.5 124.6 186.9 95.2 97.7 136.9 142.3 171.5 204.6 163.6 96.8 92.8 91.2 105.5 196.6 102.8 99.4 89.5 131.9 90.1 214.3 36.2 70.6 90.4 103.2 104.6 117.5 178.0 140.0 109.1 102.9 68.1 98.2 154.4 87.5 62.1 102.2 134.1 558.3 145.3 146.8 32.6 153.5 107.2 137.5 111.9 60.5 94.8 189.5 141.2 117.2 117.3 152.2 88.9 56.8 195.7 170.2 123.5 133.2 63.2 192.3 145.1 105.4 52.6 80.7 113.7 96.7 162.0 6.4 9.9 61.5 10.0 10.3 7.2 5.5 8.7 11.4 7.0 7.2 4.6 10.1 22.6 11.0 12.4 10.0 9.0 6.3 45.9 45.5 43.7 53.2 45.2 44.3 50.5 45.7 45.0 47.4 48.0 43.3 45.8 16.0 27.4 16.6 13.7 12.4 20.0 17.3 15.9 26.3 58.0 39.9 16.1 32.9 17.7 22.0 12.5 19.4 54.2 40.9 13.7 23.6 1.9 17.9 28.1 27.5 30.0 11.3 8.2 35.2 31.8 24.0 26.0 24.8 2.5 40.4 23.2 42.9 23.2 42.1 13.0 37.3 22.4 23.3 21.4 3.3 28.6 28.0 10.6 6.5 23.1 51.2 24.7 8.0 9.6 53.3 22.1 30.9 10.3 38.8 23.5 17.9 14.2 26.6 26.3 24.9 29.1 1.8 5.3 16.2 13.9 23.4 23.3 34.0 33.7 33.4 AKT2 PKBβ ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: AB_2685278" "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 62.8 40.0 31.7 37.3 31.3 48.4 38.6 58.3 40.0 49.8 55.1 42.3 24.5 43.5 49.4 42.5 46.1 25.1 40.8 31.5 24.5 52.2 59.2 30.7 38.1 32.0 26.0 53.9 41.9 58.5 47.8 27.6 26.3 41.2 23.3 41.2 32.5 45.0 101.3 39.4 35.6 34.2 22.1 38.1 33.1 29.7 28.0 53.4 100.1 118.7 37.0 39.8 41.5 35.2 66.2 160.1 63.1 61.5 72.0 88.9 32.5 41.7 63.5 87.6 77.9 71.8 60.8 67.4 36.8 96.3 37.2 28.2 66.8 90.0 56.1 62.5 74.3 43.4 116.5 44.7 45.8 50.7 50.5 82.7 53.6 58.6 56.4 71.9 19.0 73.0 57.3 67.5 49.8 54.6 81.1 24.7 31.7 73.7 41.5 54.2 32.1 48.5 68.3 105.7 82.7 49.8 43.3 75.0 35.0 62.5 59.8 64.9 18.8 52.7 51.5 47.3 67.6 61.5 59.0 56.4 52.6 59.7 44.3 5.7 2.6 2.1 2.2 1.2 2.2 1.9 1.8 1.5 1.7 2.9 1.7 2.6 4.0 1.7 1.6 4.9 1.6 1.7 31.7 31.3 58.3 40.0 31.5 24.5 32.0 26.0 26.3 22.1 28.0 35.2 18.1 16.0 15.9 51.2 33.0 23.8 23.9 20.9 26.2 67.6 25.3 23.9 31.2 30.0 18.1 60.7 41.7 31.3 26.0 23.7 21.5 19.7 5.5 26.2 26.7 17.4 19.2 19.1 30.4 30.4 25.2 27.9 20.9 25.8 14.0 44.2 13.9 87.5 22.3 60.6 25.3 20.1 22.4 23.2 17.5 10.5 42.9 20.0 23.2 23.4 21.7 46.2 50.4 41.7 40.6 24.8 16.9 26.7 30.4 29.7 21.8 24.8 24.9 97.4 19.7 29.3 25.0 14.8 15.6 31.1 27.4 38.7 23.1 56.9 23.3 29.4 AKT3 "PKBG, PRKBG, RAC-gamma" ENSG00000117020 "AKT serine/threonine kinase 3" Q9Y243 1 243488233-243851079 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.9" "Group enriched" "Detected in many" 6 "Astrocytes: 457.4;Excitatory neurons: 756.1;Inhibitory neurons: 514.5;Microglial cells: 414.1;Oligodendrocyte precursor cells: 633.3;Oligodendrocytes: 475.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013090, HPA026441" Approved Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB013090: AB_2533692, HPA026441: AB_1844711" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.96e-1)" "unprognostic (3.77e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-1)" "unprognostic (5.47e-3)" "unprognostic (1.37e-1)" "unprognostic (6.71e-2)" "unprognostic (3.64e-3)" "unprognostic (1.29e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (9.27e-4)" 19.3 9.7 13.4 6.0 17.0 3.8 15.5 59.9 36.6 20.0 0.0 24.5 2.6 22.7 8.6 5.9 20.3 8.2 11.8 22.8 5.6 11.2 4.7 15.3 5.9 1.2 3.9 26.4 4.5 7.4 13.9 13.1 7.4 15.8 4.9 17.0 5.1 15.6 5.9 6.3 11.8 15.7 0.8 8.1 10.2 9.7 20.3 7.0 14.4 11.5 4.6 18.8 14.8 31.1 30.8 7.2 31.0 0.4 16.9 20.6 13.9 20.8 22.5 11.8 12.9 1.1 13.9 0.5 3.0 28.9 12.1 1.2 16.3 8.5 18.9 9.0 15.3 1.0 1.0 0.3 11.7 0.6 6.5 11.3 0.3 15.5 16.9 30.3 30.2 7.2 0.5 1.1 9.0 0.9 7.6 3.3 14.4 0.3 5.1 4.2 19.7 0.6 4.8 4.1 31.4 41.9 1.3 0.5 40.1 19.1 1.9 21.5 25.6 22.7 17.7 1.1 19.5 4.6 4.6 7.1 19.4 5.2 25.3 1.3 0.8 0.1 0.6 0.1 1.1 0.6 0.6 0.6 0.3 0.8 0.6 0.7 0.7 1.4 0.3 0.5 0.1 0.3 13.4 17.0 59.9 36.6 22.8 5.6 1.2 3.9 7.4 0.8 20.3 31.1 65.4 3.2 2.2 457.4 22.2 2.4 15.0 1.3 17.1 43.6 6.1 5.1 5.4 4.3 2.7 27.6 33.3 11.0 24.4 0.0 0.0 11.6 82.8 1.7 35.5 43.7 0.0 5.0 756.1 1.7 8.0 27.9 2.6 1.1 5.1 29.7 48.2 0.6 2.9 42.1 514.5 0.0 2.0 10.5 12.5 72.8 27.4 9.5 7.2 414.1 8.6 20.1 19.6 633.3 475.9 0.7 0.0 35.3 14.4 27.0 0.0 6.9 0.3 35.0 19.7 40.1 35.6 15.0 14.6 1.7 1.7 12.4 27.8 8.3 0.0 12.2 ALB ENSG00000163631 Albumin P02768 4 73397114-73421482 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "liver: 212494.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 65190.0" "Cancer enriched" "Detected in many" 384 "liver cancer: 14213.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 38 "Hep G2: 4500.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006262, HPA031024, HPA031025" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA 40000000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Endoplasmic reticulum" "CAB006262: AB_425297, HPA031024: AB_2673703, HPA031025: AB_2673704" "unprognostic (1.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.73e-1)" "unprognostic (2.60e-1)" "unprognostic (4.44e-1)" "unprognostic (2.46e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-2)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.84e-2)" "unprognostic (5.37e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.87e-4)" "unprognostic (7.23e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" 8.3 3.7 0.9 0.0 1.0 0.0 5.9 0.6 1.3 1.9 0.6 2.5 0.0 1.8 15.4 2.6 4.3 3.8 8.2 0.7 0.9 465.2 212494.0 6.7 1.3 0.7 0.8 2.5 1569.1 1.0 3.4 4.5 0.7 2.2 0.1 0.5 2.1 0.1 1.9 3.3 2.3 0.0 0.7 37.0 10.1 3.6 1.0 0.3 3.6 0.1 1.4 0.9 1.7 0.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 18.8 0.6 0.0 0.0 1.6 0.0 0.0 0.1 0.6 0.0 31.7 2.1 4500.0 0.0 117.1 3.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 17.0 0.2 0.0 0.1 2.0 0.0 4.0 0.0 0.1 2.1 95.1 0.0 0.0 3.2 0.0 0.0 52.3 0.0 0.0 0.0 0.0 0.0 13.5 0.0 1.4 0.1 0.1 7.0 0.6 32.9 0.1 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.7 0.7 1.0 0.8 0.1 0.0 0.0 1.0 187.5 0.0 0.0 0.0 0.0 0.0 43.4 18.9 0.1 13788.8 0.0 38.6 0.0 1.4 0.6 0.1 72.4 5.3 2.5 0.2 0.1 65.5 1.8 1133.8 0.2 273.8 11.1 0.5 4.6 0.0 0.0 0.1 1252.5 65190.0 8.5 0.0 0.2 0.0 0.0 1764.5 0.0 0.1 0.0 2.9 0.0 0.0 1.0 0.0 0.0 0.0 0.1 160.6 0.0 0.0 0.0 0.2 0.0 686.5 0.0 0.0 0.0 0.0 1.1 0.2 1.3 0.0 0.1 21.2 77.1 0.1 0.0 0.1 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 26754.8;tongue: 9180.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 3267.9;Extravillous trophoblasts: 2322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004177, CAB006252" Supported Approved Cytosol NA NA 640000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB006252: AB_437007, HPA004177: AB_1078128" "unprognostic (2.63e-2)" "unprognostic (3.22e-2)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (6.74e-3)" "unprognostic (4.28e-3)" "prognostic unfavorable (5.79e-5)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.68e-1)" "unprognostic (1.81e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.19e-3)" "unprognostic (4.48e-2)" 569.3 696.4 616.8 443.1 697.4 732.5 512.6 617.3 719.7 566.0 617.0 774.1 517.9 533.7 201.0 1302.0 449.7 420.5 2286.1 731.9 652.0 709.0 217.1 425.6 358.2 762.3 654.0 510.4 390.5 943.1 525.1 351.4 763.9 457.7 400.1 465.2 904.9 597.6 26754.8 643.4 488.3 465.2 545.5 417.5 595.0 138.7 657.8 280.9 454.5 9180.4 478.3 761.8 740.3 558.7 2206.1 1620.4 477.9 1542.8 714.6 808.5 1520.8 1297.9 1336.2 1291.6 1603.0 1158.1 1643.6 1487.6 2072.2 1318.6 708.6 1632.6 966.8 2829.1 939.3 658.5 1272.9 1219.3 1202.7 2591.1 1112.5 1793.8 1251.3 1115.7 979.6 1455.4 968.9 2119.7 965.4 686.9 1070.0 951.1 1393.4 3136.7 1100.2 1477.0 1192.8 848.1 1346.6 1613.9 765.2 3353.2 1629.4 1230.5 950.7 668.5 808.6 3368.5 1213.9 591.2 1433.0 1194.7 1162.5 1892.3 750.3 1046.7 1430.0 1861.5 1387.3 1369.3 3524.5 1715.9 1532.9 2050.6 2694.7 2081.7 1008.7 2466.5 1138.1 908.5 1091.7 1047.0 2182.7 877.9 1027.4 996.9 2531.7 819.9 2780.2 824.0 1476.3 4372.2 616.8 697.4 617.3 719.7 731.9 652.0 762.3 654.0 763.9 545.5 657.8 558.7 17.0 12.8 32.4 83.2 281.2 792.0 716.4 3267.9 784.8 387.4 34.4 21.6 1968.4 273.1 1385.1 42.3 118.9 1194.1 107.9 1834.8 111.6 120.9 258.8 15.8 11.8 261.1 323.9 215.8 66.2 76.2 2322.1 329.7 513.3 16.1 196.5 18.7 289.5 102.0 1181.9 733.6 70.0 755.1 1265.4 632.2 715.4 1152.4 380.8 388.8 924.9 50.6 417.7 662.1 328.5 40.2 60.8 126.2 1497.1 405.1 409.4 676.9 1755.7 75.8 700.9 298.9 486.4 680.9 572.9 25.8 123.6 1174.6 684.5 1361.3 294.3 15.2 937.7 1146.2 ALDOB ENSG00000136872 "Aldolase, fructose-bisphosphate B" P05062 9 101420560-101449664 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "intestine: 5736.6;kidney: 7181.0;liver: 11160.8" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 20078.3;Proximal tubular cells: 7956.0" "Cancer enriched" "Detected in many" 31 "liver cancer: 1414.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 21.4;NB-4: 21.0;RPMI-8226: 28.6;SH-SY5Y: 20.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA002198, CAB020827" Enhanced NA NA 560000000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB020827: , HPA002198: AB_1078129" "unprognostic (6.58e-3)" "unprognostic (2.83e-1)" "unprognostic (1.43e-3)" "unprognostic (1.03e-1)" "unprognostic (8.10e-2)" "unprognostic (1.96e-2)" "unprognostic (1.44e-3)" "unprognostic (4.34e-2)" "unprognostic (4.57e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (7.48e-2)" "unprognostic (1.66e-2)" "unprognostic (2.02e-1)" "unprognostic (2.58e-1)" "unprognostic (5.19e-2)" "unprognostic (1.96e-2)" 3.3 1.4 0.4 17.0 0.7 0.0 0.7 1.0 2.3 0.2 0.0 30.1 4073.8 2.8 1.0 0.7 0.4 176.9 1.0 2.4 0.0 7181.0 11160.8 0.5 4.9 0.0 0.0 0.5 292.7 0.0 5.6 0.4 0.0 2.1 5.6 0.3 0.3 0.0 0.4 0.5 5736.6 7.0 0.0 2.0 34.3 1.1 0.0 0.7 0.3 0.0 0.8 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.5 0.0 4.5 1.8 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 2.2 0.0 1.0 0.0 6.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.0 0.3 21.0 0.4 0.5 0.0 0.3 4.6 28.6 0.0 0.0 4.3 20.6 2.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 1.0 7.1 0.3 0.5 0.7 2.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 1.0 2.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 39.4 0.0 0.0 0.3 0.0 1.1 0.0 0.0 1.1 308.8 0.8 150.8 0.0 0.0 0.0 13.5 620.3 4.9 0.0 0.0 0.4 3.6 0.0 50.8 0.5 253.3 0.1 0.0 0.0 0.3 0.0 0.0 49.2 3225.4 0.2 3.3 0.2 464.9 0.0 66.2 0.0 0.0 0.0 38.1 0.0 0.0 3.6 0.3 0.0 0.0 0.3 182.1 997.4 0.0 0.1 0.0 20078.3 7956.0 0.2 0.6 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.3 20.6 0.2 412.7 0.0 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.5;Horizontal cells: 274.2;Muller glia cells: 127.1;Proximal enterocytes: 120.0;Rod photoreceptor cells: 348.5" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 250.9;U-266/70: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 87.0 24.3 953.6 12.7 909.7 23.6 42.5 1238.3 1162.3 39.3 589.6 18.5 18.7 17.9 10.9 40.8 14.3 10.9 285.5 955.7 958.0 16.8 98.3 13.7 19.3 1297.5 962.6 39.1 4.9 12.1 30.6 4.1 1384.6 18.9 14.7 1183.1 19.9 15.8 4.8 74.5 43.9 12.4 926.9 24.4 23.3 14.2 1090.2 9.6 7.4 8.1 30.5 19.0 47.0 886.1 29.9 2.1 13.7 55.7 29.9 32.9 2.9 16.7 37.7 12.9 76.0 17.9 3.0 14.9 17.3 15.5 3.3 36.9 10.3 102.3 23.4 12.4 8.9 28.3 11.6 30.4 25.8 10.0 29.2 27.8 13.9 1.5 24.0 1.7 5.3 29.7 19.3 71.9 10.7 15.1 11.9 32.0 20.8 6.7 15.3 9.5 1.6 250.9 1.9 4.3 36.2 61.9 9.1 67.3 0.5 20.8 36.6 21.2 3.5 1.2 5.3 2.1 2.4 161.0 51.4 10.9 105.2 28.0 1.9 0.5 7.4 3.0 21.6 8.7 30.6 24.0 29.5 17.8 9.4 25.1 37.7 28.4 18.0 29.4 5.3 4.6 40.9 19.0 953.6 909.7 1238.3 1162.3 955.7 958.0 1297.5 962.6 1384.6 926.9 1090.2 886.1 4.2 0.0 15.8 97.6 9.8 7.5 20.3 80.5 8.6 112.5 9.0 11.0 22.1 11.5 29.3 7.3 106.3 1.1 9.5 31.7 3.9 21.9 0.9 1.0 3.0 11.3 21.6 3.2 19.2 10.2 6.5 5.8 6.6 1.2 13.3 4.9 14.3 93.1 5.4 274.2 41.3 12.9 28.5 4.4 5.3 1.3 9.3 3.1 24.9 21.5 34.1 127.1 12.3 26.7 16.8 12.4 12.4 10.1 2.6 6.1 120.0 2.1 11.8 348.5 13.1 6.4 10.1 0.3 3.2 7.9 10.9 1.5 17.0 11.7 5.1 7.8 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 10.9" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 31.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 0.3 0.6 2.2 0.2 2.4 0.0 0.1 0.7 2.8 0.1 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.5 3.9 0.0 0.0 0.1 0.0 4.4 6.8 0.0 0.0 0.0 1.3 0.0 10.9 0.0 0.2 0.7 0.1 0.1 0.0 0.1 0.3 0.1 2.9 0.0 0.1 1.2 2.7 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 4.3 0.0 0.0 0.1 0.4 31.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.7 2.8 1.5 3.9 4.4 6.8 10.9 2.9 2.7 2.1 0.0 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 0.5 0.1 0.2 0.0 0.0 12.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 274.2 0.0 0.0 0.0 0.0 41.2 0.0 0.5 0.0 7.5 0.0 0.6 0.0 433.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ALKBH6 MGC15677 ENSG00000239382 "AlkB homolog 6" Q3KRA9 19 36009120-36014239 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073835, HPA074340" Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "Focal adhesion sites" "HPA073835: AB_2686637, HPA074340: AB_2686680" "unprognostic (1.90e-3)" "unprognostic (1.82e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.24e-1)" "unprognostic (5.86e-5)" "unprognostic (6.21e-2)" "unprognostic (4.53e-2)" "unprognostic (3.95e-1)" "unprognostic (3.56e-2)" "unprognostic (8.78e-4)" "unprognostic (1.77e-2)" "unprognostic (2.31e-5)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (3.82e-1)" "unprognostic (1.05e-3)" 5.4 8.4 9.3 3.1 8.3 3.3 5.3 9.7 12.4 6.6 6.9 9.8 2.9 7.6 2.3 7.6 6.7 2.1 6.8 9.3 12.3 7.2 11.5 5.5 4.3 15.7 10.3 5.6 4.4 4.7 9.9 2.7 15.0 7.6 1.9 2.7 6.1 4.0 6.4 6.3 7.3 3.7 8.3 7.9 7.8 4.5 12.7 4.1 6.6 3.9 3.8 7.9 6.0 10.6 12.5 13.1 4.9 7.2 7.4 4.5 8.2 12.1 8.0 13.9 14.0 5.4 6.4 10.8 18.8 6.7 7.2 4.9 5.1 14.0 7.2 17.2 9.4 6.2 5.1 5.9 8.4 5.4 18.3 6.8 9.9 11.5 3.9 4.8 9.5 16.2 9.9 8.0 7.5 13.1 13.1 7.0 3.8 12.8 8.3 8.4 6.7 7.9 10.3 5.5 5.9 6.0 8.2 9.8 10.8 6.8 7.8 12.1 4.1 7.2 10.5 16.6 12.0 14.9 9.6 7.8 15.5 6.1 7.8 58.5 18.2 47.8 26.2 26.0 20.4 32.9 23.8 25.4 16.0 24.6 20.2 19.3 16.0 28.8 20.7 22.7 34.4 16.0 9.3 8.3 9.7 12.4 9.3 12.3 15.7 10.3 15.0 8.3 12.7 10.6 6.1 3.2 1.7 6.8 16.5 6.8 11.1 4.5 9.1 5.6 8.0 6.5 2.0 10.0 3.3 18.4 0.0 17.7 13.1 9.5 5.9 10.4 7.6 6.8 5.0 5.9 13.1 14.5 8.1 9.2 15.8 8.1 14.3 6.3 0.0 7.1 7.9 12.7 11.0 10.1 7.2 11.9 2.0 5.3 7.7 5.4 11.1 9.1 8.8 3.7 15.2 5.5 23.7 2.0 6.5 13.3 13.6 4.5 12.1 7.1 7.8 11.8 2.3 3.3 6.6 4.1 10.1 3.6 2.4 8.7 5.1 19.0 15.5 6.4 9.5 9.5 ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58629091 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 41.9;skeletal muscle: 38.3;tongue: 33.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 120.4;Cone photoreceptor cells: 47.9;Early spermatids: 15.9;Late spermatids: 24.3;monocytes: 18.1" "Cancer enriched" "Detected in some" 6 "renal cancer: 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 51.2;BJ hTERT+: 31.0;fHDF/TERT166: 46.6;U-138 MG: 25.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006" "unprognostic (7.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.60e-3)" "unprognostic (2.64e-1)" "unprognostic (8.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (5.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (3.20e-2)" 0.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.3 0.0 0.9 41.9 0.4 0.0 9.2 4.5 0.1 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 2.1 0.3 0.0 38.3 0.5 1.0 0.1 0.0 0.5 1.7 1.1 0.0 3.5 0.0 33.2 4.4 1.5 0.0 0.0 0.0 13.7 0.9 0.0 0.4 3.4 0.3 51.2 31.0 21.2 18.1 3.4 0.0 0.0 5.2 46.6 2.9 0.0 0.0 0.0 21.5 11.5 0.0 0.0 4.4 1.8 2.7 0.0 0.0 3.0 0.0 6.4 0.2 0.7 0.0 0.0 0.0 0.4 13.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 11.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 8.3 0.0 0.0 0.0 25.3 11.2 3.5 8.7 20.9 19.2 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.1 4.8 120.4 0.0 0.0 0.0 47.9 0.0 0.1 0.0 1.9 1.5 15.9 0.0 2.3 0.9 0.0 0.0 1.0 0.7 0.0 8.9 0.0 0.1 0.0 4.0 0.4 3.0 0.7 1.7 0.7 0.0 0.0 0.3 3.0 24.3 0.3 2.4 0.0 0.0 18.1 2.6 0.0 0.0 0.8 0.2 2.3 0.0 0.6 0.0 0.3 13.6 0.0 0.9 0.0 3.8 1.7 1.1 0.1 0.0 0.9 0.1 0.3 0.0 0.0 0.0 ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 92.0;Breast myoepithelial cells: 32.4;Glandular and luminal cells: 43.3;Hepatic stellate cells: 40.7;Hepatocytes: 30.1;Proximal tubular cells: 43.9;Rod photoreceptor cells: 34.2" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 379.1" "Lineage enriched" "Detected in many" 139 "granulocytes: 379.1" "Cell line enhanced" "Detected in many" "HSkMC: 176.9;hTEC/SVTERT24-B: 141.2;LHCN-M2: 103.7;NTERA-2: 41.2;SCLC-21H: 88.2;SuSa: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" 24.7 60.7 19.5 27.9 16.7 4.2 22.9 18.0 25.8 3.4 26.0 5.0 2.6 5.8 1.3 4.1 10.4 3.9 16.4 17.8 18.8 45.7 56.3 54.9 6.4 21.7 17.7 2.8 3.9 3.3 9.3 3.1 22.4 7.1 1.5 18.8 6.4 9.2 1.1 4.2 7.5 3.5 18.2 45.5 4.7 4.2 21.3 1.5 8.6 5.7 5.9 9.7 3.3 17.3 0.0 0.2 5.2 0.2 0.8 6.6 11.4 0.4 2.4 0.9 1.5 1.0 0.0 2.4 7.7 0.0 0.1 0.1 31.3 0.2 0.6 0.0 2.1 0.0 3.5 3.9 1.8 0.0 0.7 176.9 0.0 141.2 0.5 0.0 0.0 0.0 0.2 0.0 103.7 0.0 0.1 0.0 41.2 0.2 0.0 0.0 3.8 0.2 0.1 0.0 88.2 1.2 0.0 0.1 0.3 48.1 0.2 0.0 0.0 5.2 4.3 0.1 0.0 0.3 0.0 0.1 0.9 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 379.1 0.0 0.0 0.0 0.0 0.1 19.5 16.7 18.0 25.8 17.8 18.8 21.7 17.7 22.4 18.2 21.3 17.3 25.9 3.2 92.0 0.3 3.8 0.1 0.6 8.2 0.6 2.5 6.6 32.4 2.1 2.8 17.6 0.0 0.0 0.1 0.1 0.0 7.9 0.0 1.4 15.0 2.2 26.5 0.0 5.7 0.9 0.0 0.3 6.8 0.0 43.3 7.6 10.6 40.7 30.1 0.1 1.7 0.3 0.0 12.2 1.6 0.3 8.5 0.3 1.0 0.0 18.7 0.0 6.0 0.0 6.0 0.2 0.0 0.0 0.0 0.3 1.7 0.0 43.9 3.6 34.2 0.0 0.3 5.1 0.4 14.0 0.2 0.4 1.5 1.0 8.0 0.0 0.3 ALPP "PALP, PLAP" ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378724-232382889 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 17.8;placenta: 34.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 12.8;Glandular and luminal cells: 5.0;Syncytiotrophoblasts: 6.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 381.0;SiHa: 103.6" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB026327: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 17.8 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 34.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.5 42.9 0.0 0.1 0.0 0.1 381.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 103.6 35.3 0.0 3.5 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 6.7 0.1 0.2 0.0 0.0 AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 15.3" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 1.1 1.4 1.6 1.3 1.5 1.2 1.3 1.8 1.6 1.9 0.1 1.5 1.5 1.9 4.0 2.8 2.2 1.0 1.3 1.0 1.6 1.8 2.1 1.2 1.2 1.5 1.4 6.3 2.0 1.6 0.7 0.8 1.5 1.7 1.3 1.3 2.2 2.2 4.1 2.2 1.3 2.8 0.7 1.3 1.6 0.4 1.9 1.6 1.4 15.3 1.6 1.3 1.3 1.0 3.1 2.2 5.8 4.6 2.2 2.1 4.7 1.4 1.2 2.1 1.3 7.3 1.1 5.9 1.8 3.0 1.6 4.3 12.5 4.1 2.0 2.5 2.5 3.7 4.9 4.9 1.6 7.7 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.6 5.6 5.9 1.1 3.7 5.2 4.0 15.6 4.0 4.4 11.7 9.4 4.3 0.9 1.0 2.6 3.9 3.7 5.0 1.9 4.8 1.6 2.1 0.8 2.5 5.8 6.7 1.9 3.0 2.2 4.4 1.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.5 1.8 1.6 1.0 1.6 1.5 1.4 1.5 0.7 1.9 1.0 0.9 0.0 0.0 1.0 1.5 2.2 0.6 0.9 2.8 5.0 1.7 1.5 2.6 4.3 0.3 0.0 2.1 1.1 3.4 1.1 0.0 1.2 0.1 3.3 2.6 1.5 1.2 0.8 0.8 1.6 0.8 1.8 3.6 2.0 0.0 3.9 1.4 2.6 0.4 0.0 1.3 1.0 0.0 1.0 0.3 0.2 2.5 0.5 1.8 1.0 1.2 0.2 0.0 1.0 0.6 0.7 0.5 4.1 2.4 1.2 0.8 0.8 0.0 1.0 6.6 2.3 4.4 0.0 0.2 3.6 2.6 0.7 0.9 6.4 1.6 0.7 AMPH ENSG00000078053 Amphiphysin P49418 7 38383704-38631420 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 48.9;pituitary gland: 21.3;retina: 65.9" "Group enriched" "Detected in many" 5 "Bipolar cells: 72.2;Cone photoreceptor cells: 87.6;Excitatory neurons: 228.2;Inhibitory neurons: 198.4;Oligodendrocyte precursor cells: 96.5;Rod photoreceptor cells: 59.4" "Cancer enhanced" "Detected in many" "glioma: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 64.6;ASC TERT1: 37.8;BJ hTERT+ SV40 Large T+: 25.4;BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 44.8;HBF TERT88: 23.1;U-138 MG: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008559, HPA019828, HPA019829" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "CAB008559: AB_1611845, HPA019828: AB_1844801, HPA019829: AB_1844802" "unprognostic (1.76e-2)" "unprognostic (1.59e-1)" "unprognostic (5.94e-2)" "unprognostic (7.36e-2)" "unprognostic (3.24e-3)" "unprognostic (2.92e-1)" "unprognostic (4.90e-2)" "unprognostic (2.55e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "prognostic favorable (9.96e-4)" "unprognostic (5.06e-2)" "unprognostic (5.81e-5)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 6.5 1.3 19.2 1.5 21.9 0.0 5.9 7.2 48.9 5.8 0.0 3.7 0.5 4.0 3.4 3.2 4.7 3.0 5.4 27.3 28.8 2.6 0.4 1.0 0.4 11.2 0.8 0.9 1.8 0.3 21.3 0.0 10.9 1.4 1.4 65.9 2.5 2.9 3.6 1.3 1.8 3.8 7.9 1.9 2.8 2.5 5.4 0.7 1.7 9.6 0.2 2.4 2.9 17.5 0.0 0.0 16.7 0.0 64.6 37.8 0.0 2.4 0.0 25.4 29.9 0.0 0.0 0.0 0.0 4.8 44.8 0.0 0.0 0.0 23.1 0.0 2.0 0.2 0.0 0.0 0.0 0.3 0.1 22.4 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.5 0.1 0.3 0.0 0.3 8.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 4.9 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.0 24.6 17.1 8.8 9.8 0.1 0.3 0.0 16.8 0.3 22.6 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.4 0.0 0.0 19.2 21.9 7.2 48.9 27.3 28.8 11.2 0.8 10.9 7.9 5.4 17.5 0.8 0.0 0.0 22.5 0.6 0.3 0.1 0.0 0.0 72.2 3.1 2.2 7.9 0.0 0.0 0.0 87.6 0.0 0.3 0.0 1.9 0.3 9.9 0.4 3.2 1.1 0.0 0.0 228.2 0.0 0.0 8.6 0.0 0.3 0.0 0.2 3.9 0.1 0.1 1.7 198.4 0.0 0.0 13.0 1.1 15.0 2.8 0.7 0.0 22.5 0.5 7.6 3.1 96.5 5.5 0.1 0.0 4.9 0.1 0.0 0.0 0.0 0.0 59.4 6.6 8.3 8.4 4.7 2.8 0.0 0.3 0.0 0.6 2.0 0.0 0.0 ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Vesicles "HPA036329: AB_10670714, HPA036330: AB_2675065, HPA042998: AB_2678263" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.49e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" 6.4 4.8 4.1 9.5 5.1 8.3 9.2 4.8 5.1 6.9 9.8 9.9 8.3 8.0 4.9 8.1 7.8 5.8 5.8 4.7 3.6 6.2 5.6 5.4 12.1 4.1 4.1 8.4 6.3 10.4 4.6 7.7 5.1 6.4 10.5 7.9 5.4 6.2 12.2 6.8 6.5 7.6 3.7 7.8 6.6 10.2 4.0 12.6 6.3 9.4 12.4 8.4 5.8 5.2 42.4 31.0 33.1 23.9 14.9 18.4 32.6 25.0 18.8 30.3 26.5 60.4 26.6 72.7 19.9 23.0 36.0 35.4 51.0 28.4 40.4 31.7 31.9 81.6 27.6 37.1 14.3 85.0 27.4 13.8 14.3 44.9 40.8 15.4 29.5 34.9 75.8 30.8 21.5 20.2 51.9 25.5 50.3 18.3 26.1 51.1 39.4 41.1 19.1 41.6 26.2 16.0 26.2 23.9 22.8 21.8 14.1 30.1 20.9 26.5 28.5 21.7 26.9 23.0 52.5 67.1 21.5 36.9 21.9 0.0 2.1 0.6 4.2 2.2 6.1 4.0 3.8 3.6 3.9 3.1 5.4 5.2 0.4 4.8 1.9 1.8 1.8 3.3 4.1 5.1 4.8 5.1 4.7 3.6 4.1 4.1 5.1 3.7 4.0 5.2 14.5 3.2 8.2 17.0 20.3 14.3 20.5 7.6 22.2 11.2 12.1 11.8 7.5 8.6 6.0 3.7 14.6 12.2 25.4 7.2 5.9 5.9 6.6 13.5 13.4 11.0 11.4 17.9 32.5 5.9 12.7 12.0 12.2 11.7 8.2 19.2 8.6 12.8 9.0 20.2 32.6 11.1 14.2 8.4 11.8 8.6 10.2 12.2 7.2 12.2 8.8 7.7 13.4 21.6 31.3 7.1 5.4 9.4 14.4 24.6 5.6 8.8 8.2 16.0 13.1 15.9 11.5 17.3 21.0 18.0 20.2 6.7 21.2 12.2 14.5 23.4 ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 3018.1" "Cell type enriched" "Detected in many" 24 "Hepatocytes: 4816.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.5;myeloid DC: 14.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Hep G2: 152.2;OE19: 116.1" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" Yes No 308000000 410000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" 37.6 3.0 3.6 6.0 3.5 1.0 37.8 3.5 4.9 38.2 5.6 32.6 23.2 23.4 17.9 9.8 30.5 28.5 16.9 3.6 4.9 18.4 3018.1 18.5 3.5 4.5 4.2 58.1 30.8 5.3 5.0 3.8 4.3 32.7 45.7 2.2 52.6 13.3 6.2 27.4 27.1 10.4 4.5 7.4 58.2 10.2 3.7 1.5 8.8 10.5 4.1 24.8 31.4 4.8 3.7 9.9 2.3 0.0 23.9 27.8 0.3 4.8 8.8 1.1 4.0 5.9 5.1 0.4 1.5 12.0 8.0 3.8 2.8 3.1 1.3 18.4 3.8 0.9 5.1 152.2 5.0 4.0 0.5 22.2 2.5 1.5 5.1 11.8 5.7 4.2 0.2 27.0 3.5 0.7 0.9 1.2 0.7 116.1 10.7 0.7 3.9 11.3 2.3 2.9 0.0 0.4 4.6 1.7 6.5 5.1 4.0 0.7 6.0 1.9 2.8 1.7 0.7 5.9 4.8 0.5 3.2 2.0 5.0 0.0 24.5 0.0 0.6 2.9 0.4 5.8 1.2 1.1 14.5 4.9 0.3 0.2 0.4 0.0 0.1 2.3 0.8 7.1 3.6 3.5 3.5 4.9 3.6 4.9 4.5 4.2 4.3 4.5 3.7 4.8 9.7 28.9 17.7 0.0 9.7 27.1 43.3 39.2 14.2 0.1 33.8 24.8 0.8 194.5 24.6 11.0 0.0 1.6 0.7 32.5 11.7 40.0 1.0 6.2 9.7 11.0 71.0 27.8 0.0 31.6 5.3 48.8 56.1 24.9 0.0 10.7 62.4 4816.3 15.9 0.0 0.0 171.9 12.2 95.9 18.7 2.9 71.1 13.8 23.2 0.0 4.9 10.1 0.0 0.0 0.0 21.6 33.3 24.0 11.7 43.7 91.3 61.2 76.5 0.6 13.1 29.7 17.7 1.0 1.3 9.4 52.4 9.3 5.6 0.5 51.6 39.2 ANGPT1 "Ang1, KIAA0003" ENSG00000154188 "Angiopoietin 1" Q15389 8 107249482-107498055 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 33.5" "Group enriched" "Detected in many" 4 "Astrocytes: 60.4;Fibroblasts: 20.4;Inhibitory neurons: 37.6;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.8" "Cell line enhanced" "Detected in many" "ASC diff: 87.9;HEL: 53.1;HSkMC: 145.5;U-138 MG: 70.5;WM-115: 47.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017815, HPA018793, HPA018816" Approved "Secreted to blood" NA NA 32000000 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB017815: , HPA018793: AB_1844820, HPA018816: AB_1844821" "unprognostic (7.71e-2)" "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (4.11e-3)" "unprognostic (7.36e-2)" "unprognostic (3.80e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (1.07e-2)" "unprognostic (5.54e-2)" "unprognostic (2.62e-1)" "unprognostic (1.44e-1)" "prognostic favorable (4.40e-4)" "unprognostic (4.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" 25.1 5.6 3.2 2.6 4.5 0.7 4.6 4.5 2.2 5.8 2.5 3.4 2.3 3.5 4.8 3.5 3.0 13.2 4.8 4.5 6.1 11.1 2.1 21.7 1.4 8.0 3.5 9.5 1.6 1.2 5.8 20.5 4.8 17.7 3.3 0.6 12.0 33.5 23.4 1.2 2.6 3.3 4.8 11.0 4.0 2.3 2.1 2.1 3.5 7.0 1.0 3.9 3.7 11.9 0.0 2.4 9.3 5.3 87.9 30.2 6.6 30.0 25.8 8.1 11.9 6.2 0.1 0.0 0.1 16.0 0.0 0.0 4.2 0.1 10.5 0.0 1.4 53.1 0.6 0.0 24.5 0.7 0.0 145.5 0.0 4.9 0.6 7.5 0.6 0.0 28.2 5.1 10.9 0.0 1.1 7.9 9.6 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.1 4.2 1.1 0.6 0.0 11.6 2.2 0.0 0.3 70.5 0.9 2.5 0.7 0.2 3.2 0.0 9.7 1.1 47.5 0.1 0.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.8 0.1 0.3 0.0 0.0 0.6 3.2 4.5 4.5 2.2 4.5 6.1 8.0 3.5 4.8 4.8 2.1 11.9 9.0 0.0 2.3 60.4 0.0 0.6 10.1 0.4 5.2 0.9 0.5 2.8 3.3 0.0 2.2 7.3 0.0 5.2 0.0 0.0 1.9 0.3 8.1 0.7 9.1 5.6 0.0 10.1 6.5 0.0 7.6 20.4 1.5 1.9 0.0 0.0 3.3 0.1 0.5 0.0 37.6 0.0 2.0 0.3 1.0 2.4 2.5 2.9 0.0 6.5 1.5 0.5 0.0 3.0 0.6 0.0 0.0 3.8 1.1 1.2 0.0 2.8 0.8 0.0 6.6 3.5 48.6 1.6 5.4 4.0 0.1 2.7 0.8 1.7 0.1 1.2 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANK3 ENSG00000151150 "Ankyrin 3" Q12955 10 60026298-60733490 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism spectrum disorder, Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 490.2;Excitatory neurons: 859.2;Inhibitory neurons: 881.3;Oligodendrocyte precursor cells: 592.6;Oligodendrocytes: 1579.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 50.3;SK-BR-3: 49.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013249, CAB015179, HPA038455" Enhanced Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB013249: AB_2533145, CAB015179: AB_633909, HPA038455: AB_2676020" "unprognostic (1.91e-1)" "unprognostic (5.33e-3)" "unprognostic (6.76e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" "unprognostic (1.21e-2)" "unprognostic (3.83e-1)" "unprognostic (2.28e-2)" "prognostic favorable (8.88e-16)" "unprognostic (5.75e-2)" "unprognostic (2.59e-1)" "unprognostic (1.00e-1)" "unprognostic (2.83e-2)" 6.3 6.7 45.5 6.5 86.5 2.1 21.5 144.9 82.3 12.0 0.0 26.0 39.3 23.0 125.2 16.9 19.1 21.5 81.1 60.8 86.1 95.4 16.6 24.6 6.1 82.7 61.3 11.6 11.2 131.8 14.5 15.6 97.0 20.0 20.9 123.2 42.6 40.5 80.5 39.9 27.2 13.2 21.2 10.8 15.5 8.0 87.3 9.1 41.6 94.1 7.4 10.8 14.1 114.4 8.7 4.9 30.3 0.4 0.0 1.8 23.3 0.6 0.4 0.1 0.6 22.2 16.6 0.5 9.8 0.6 0.9 12.1 16.4 14.9 0.5 0.5 11.0 0.2 9.7 0.1 6.2 0.1 0.4 14.6 9.3 7.8 0.4 26.1 3.6 0.0 4.3 20.6 6.9 29.0 0.2 1.0 13.8 23.3 26.6 0.1 21.7 4.3 5.4 50.3 15.6 2.8 0.6 49.4 0.0 33.6 28.7 0.1 10.0 0.9 2.9 13.3 1.5 0.9 0.2 0.2 5.5 0.2 18.9 1.6 0.2 0.5 2.7 0.2 2.4 4.1 4.6 1.5 0.1 1.1 5.0 1.2 0.7 1.5 0.3 2.5 0.8 1.0 45.5 86.5 144.9 82.3 60.8 86.1 82.7 61.3 97.0 21.2 87.3 114.4 0.9 44.8 174.3 20.2 14.5 19.1 21.9 17.8 38.7 490.2 26.8 20.6 189.3 12.8 42.5 53.3 225.2 38.8 3.4 62.9 19.6 10.6 28.3 139.8 26.2 3.9 30.6 0.0 859.2 8.6 9.9 13.2 15.8 153.3 12.6 66.9 7.9 0.5 4.7 43.7 881.3 12.1 14.2 4.8 1.4 11.5 28.0 3.3 8.8 23.4 4.4 41.4 0.0 592.6 1579.5 4.8 41.8 5.7 3.4 12.2 62.5 51.3 66.7 216.6 0.0 30.2 11.7 1.1 2.3 35.9 18.2 25.0 18.5 4.5 17.8 18.4 ANKRD12 "FLJ20053, GAC-1, KIAA0874" ENSG00000101745 "Ankyrin repeat domain 12" Q6UB98 18 9136228-9285985 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040705 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA040705: AB_10673301" "unprognostic (2.20e-1)" "unprognostic (1.14e-1)" "unprognostic (3.59e-1)" "unprognostic (1.37e-1)" "unprognostic (1.46e-1)" "unprognostic (3.41e-3)" "unprognostic (7.25e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (3.38e-1)" "unprognostic (2.39e-2)" "unprognostic (4.62e-1)" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.03e-2)" 15.8 9.3 17.1 20.5 21.4 20.5 13.7 59.9 26.0 11.1 2.2 13.0 12.9 11.8 9.5 14.4 6.2 14.6 11.9 13.9 18.4 13.0 13.8 11.5 22.4 11.2 13.4 14.1 11.9 10.5 5.9 14.1 13.2 12.2 12.0 29.8 12.3 10.6 26.7 20.2 13.4 9.1 10.4 19.9 14.5 27.7 15.8 11.4 16.4 12.3 18.5 13.5 8.0 32.3 10.1 6.7 9.0 6.0 14.2 14.5 7.3 15.3 14.2 5.4 7.4 6.1 7.6 13.9 8.7 10.6 16.4 9.1 6.8 6.0 14.5 14.8 8.1 6.4 4.7 9.0 10.5 15.0 19.7 7.6 13.1 7.7 12.4 12.2 9.2 8.0 14.7 106.4 13.2 5.7 10.1 10.2 3.4 24.7 6.8 9.0 12.6 51.1 7.1 15.8 20.9 7.7 15.0 7.4 11.1 8.0 9.2 12.4 19.9 39.5 18.1 32.1 14.4 30.8 52.0 25.9 19.4 7.9 15.2 102.0 26.4 85.1 42.4 24.1 47.9 63.6 54.9 42.0 19.2 56.2 55.9 43.4 157.3 30.4 37.2 60.6 44.0 18.3 17.1 21.4 59.9 26.0 13.9 18.4 11.2 13.4 13.2 10.4 15.8 32.3 235.1 278.9 261.5 198.5 246.9 108.2 205.9 83.3 116.7 301.0 87.5 108.5 138.6 94.4 137.7 68.0 523.3 46.3 267.2 163.1 19.6 99.7 204.9 144.3 91.9 136.8 92.7 90.7 172.1 83.5 41.1 126.8 64.2 292.9 187.2 76.3 121.7 74.0 67.8 286.0 218.1 90.4 107.8 99.7 126.2 230.9 134.8 149.3 90.7 161.1 178.2 125.5 244.1 184.5 347.4 93.0 147.1 141.4 210.1 196.8 126.1 37.0 88.5 315.4 111.7 173.2 150.0 239.5 152.8 70.9 96.0 78.1 298.3 63.0 71.0 170.7 ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7527.7" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 3632.9;Syncytiotrophoblasts: 7071.8;Urothelial cells: 4808.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2816.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA Yes 3000000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" 719.8 60.3 27.5 268.3 35.1 2132.2 442.6 24.8 44.4 952.0 32.8 152.7 64.1 116.2 58.6 7527.7 264.6 329.4 145.3 28.4 53.4 67.9 54.7 470.4 67.9 55.5 46.4 109.4 61.8 28.2 98.1 559.4 36.5 165.3 103.2 6.5 1547.5 154.9 47.6 213.8 88.7 261.5 40.4 79.6 90.2 17.9 45.9 109.9 206.8 89.1 1485.5 386.3 1536.1 43.2 960.2 1485.7 65.8 68.4 905.8 855.6 4.2 1614.6 1008.5 656.3 441.9 43.5 841.0 2.2 520.1 1426.5 1441.9 1147.7 142.6 984.1 516.8 541.6 10.3 73.2 398.5 1.4 719.4 160.9 34.7 495.7 800.6 664.7 1294.6 604.0 947.8 85.4 309.3 39.5 822.6 4.3 287.0 87.7 82.6 379.7 597.6 0.9 369.1 3.2 1495.9 200.4 1.0 0.7 556.6 14.7 377.9 862.7 3.5 24.3 1176.2 761.8 478.9 1058.2 845.1 6.8 2.0 3.6 1757.9 147.8 1171.2 2816.9 1237.6 2227.6 744.1 328.7 757.0 13.7 662.7 664.5 1513.3 3.3 190.7 348.5 128.4 443.6 324.0 53.2 134.5 2021.5 27.5 35.1 24.8 44.4 28.4 53.4 55.5 46.4 36.5 40.4 45.9 43.2 447.4 583.3 415.2 1.6 39.0 846.7 2486.8 2417.6 1748.3 0.1 225.0 417.1 22.5 58.6 2214.7 62.5 0.0 1543.4 602.1 32.2 0.0 167.4 8.2 2037.4 241.6 362.2 5.3 81.2 3.7 23.1 1747.7 732.0 86.6 1993.5 2550.6 0.1 136.7 6.5 593.8 0.0 0.1 20.8 1330.6 545.0 1190.3 7.3 222.4 901.7 307.7 29.0 575.0 0.2 319.3 0.5 0.6 733.2 5.5 9.4 140.4 1552.2 0.1 5.7 1996.9 0.0 65.7 728.2 413.3 2.3 4.0 3632.9 597.7 7071.8 1348.3 3.0 12.6 4808.1 ANXA11 ANX11 ENSG00000122359 "Annexin A11" P50995 10 80150889-80205572 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 443.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004851, HPA027545" Supported Supported Nucleoplasm,Cytosol NA NA 210000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB004851: AB_626682, HPA027545: AB_1844851" "unprognostic (1.85e-2)" "unprognostic (2.85e-2)" "unprognostic (5.35e-3)" "unprognostic (5.06e-2)" "unprognostic (8.18e-3)" "unprognostic (1.99e-1)" "unprognostic (4.01e-3)" "unprognostic (6.28e-2)" "unprognostic (2.32e-2)" "unprognostic (4.88e-2)" "unprognostic (3.46e-2)" "unprognostic (2.56e-2)" "prognostic favorable (6.69e-8)" "unprognostic (2.69e-3)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (2.02e-1)" 139.9 29.5 39.0 99.4 40.6 192.9 107.6 27.5 46.8 86.6 52.8 130.3 138.0 74.3 107.5 210.2 109.0 84.8 236.2 47.3 29.0 144.7 47.7 109.5 81.2 26.4 26.6 78.2 95.4 81.8 27.2 91.1 23.9 100.3 120.7 4.8 94.1 81.8 188.9 75.6 137.2 86.0 25.4 76.2 139.3 24.5 24.6 100.2 61.4 166.2 101.7 148.1 102.8 30.4 221.7 195.7 10.4 53.9 220.2 201.1 119.6 149.5 397.3 95.7 98.8 168.7 338.2 13.1 113.6 236.7 8.1 277.7 44.6 136.2 54.2 384.3 76.0 84.4 98.9 131.5 129.4 92.0 212.3 222.9 74.6 57.8 39.4 178.9 143.9 117.9 82.1 163.7 76.8 127.3 119.8 200.9 19.6 211.5 367.7 91.7 14.9 344.0 155.1 191.8 5.1 37.9 65.0 269.9 156.4 83.4 80.6 120.6 160.0 68.7 101.4 157.6 84.4 91.7 145.6 96.0 66.6 155.4 47.4 130.8 66.8 443.8 72.9 52.4 75.0 64.9 92.5 100.5 49.4 54.2 83.7 74.4 231.8 61.3 59.1 78.5 126.5 85.4 39.0 40.6 27.5 46.8 47.3 29.0 26.4 26.6 23.9 25.4 24.6 30.4 150.5 96.1 78.4 17.3 101.4 51.2 266.4 219.4 92.8 1.6 58.8 50.4 293.3 203.0 227.1 220.7 0.0 271.7 137.1 457.7 332.6 429.2 4.5 180.6 49.7 82.7 77.5 29.9 29.5 352.5 309.8 113.1 175.8 265.7 116.1 81.4 91.4 40.8 228.1 3.3 15.5 186.9 97.6 149.7 167.4 9.6 92.9 155.0 90.7 24.4 208.2 38.9 159.6 3.0 2.3 420.6 461.0 92.6 98.2 414.9 367.7 156.8 229.0 2.8 92.1 56.4 137.9 2.8 51.5 98.4 42.1 185.5 131.9 50.8 227.8 581.4 ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2185.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5755.6;Pancreatic endocrine cells: 5217.8;Prostatic glandular cells: 4575.5;Urothelial cells: 4326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4429.7;classical monocyte: 2762.3;intermediate monocyte: 2401.9;myeloid DC: 4018.8;non-classical monocyte: 2686.5;T-reg: 1681.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 174.7" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 19000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" 975.6 370.5 49.0 461.9 50.5 151.7 708.5 49.6 96.9 806.3 95.6 631.2 502.0 296.2 267.2 2185.3 388.4 453.9 393.0 47.6 79.4 358.3 185.5 878.3 200.7 90.0 83.6 187.0 324.3 344.0 163.9 650.4 84.9 399.3 606.1 30.2 933.4 386.4 304.8 1140.8 487.5 425.4 73.3 301.6 379.0 116.1 120.9 188.7 351.2 205.8 541.1 842.2 1256.7 80.1 4183.3 4421.4 223.6 105.5 2962.4 4744.2 971.0 4703.6 2968.4 2868.4 2534.9 2083.5 1903.6 10.0 3907.2 5983.6 2185.1 4304.9 992.9 8695.5 3113.5 846.8 103.9 78.2 1918.7 882.7 1782.0 4.5 59.9 2324.4 2278.6 2013.2 4335.0 3477.2 5455.0 58.4 320.9 447.9 6271.8 468.4 18.5 239.1 508.2 3444.1 3283.5 48.9 1198.8 226.6 5172.4 2410.7 295.1 171.9 1774.5 424.8 1942.8 2305.1 922.7 173.6 6336.8 2534.1 3406.8 8668.0 4807.4 172.6 616.3 83.8 2449.2 47.9 5206.0 4429.7 2762.3 355.0 603.8 2401.9 668.5 657.9 686.4 701.7 4018.8 412.1 77.0 313.9 73.6 287.1 2686.5 609.4 1681.4 3754.4 49.0 50.5 49.6 96.9 47.6 79.4 90.0 83.6 84.9 73.3 120.9 80.1 673.9 2141.0 414.8 0.3 101.3 2512.2 3396.9 5755.6 246.4 2.5 395.9 337.4 28.2 773.5 3086.6 560.9 0.0 1874.5 135.9 933.6 13.7 3941.4 93.0 855.9 457.1 772.0 103.4 38.7 0.2 2411.4 2714.4 1076.7 328.7 1376.3 105.7 97.5 474.0 64.2 1537.2 0.0 1.3 689.0 1668.2 429.6 1992.1 126.6 771.1 715.1 1417.6 15.9 1284.0 19.4 138.0 1.5 0.1 5217.8 920.9 638.7 144.5 4575.5 845.8 51.8 2446.8 8.1 184.1 437.7 831.1 13.0 29.3 789.7 2325.1 1150.1 224.1 8.6 749.9 4326.1 ANXA4 ANX4 ENSG00000196975 "Annexin A4" P09525 2 69644425-69827112 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 569.9;pancreas: 356.8" "Cell type enhanced" "Detected in all" "Cholangiocytes: 2344.8;Ductal cells: 1469.8;Proximal enterocytes: 657.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 414.2;Hep G2: 456.9;RPTEC TERT1: 623.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005076, HPA007393, CAB017560" Enhanced Approved Cytosol NA NA 550000 "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 1: Pancreatic cells - Digestion" Cytosol "CAB005076: AB_630869, CAB017560: AB_2227370, HPA007393: AB_1078168" "prognostic unfavorable (8.55e-4)" "unprognostic (3.37e-2)" "unprognostic (4.82e-2)" "unprognostic (9.03e-2)" "unprognostic (1.62e-3)" "unprognostic (1.66e-1)" "unprognostic (3.57e-1)" "unprognostic (3.21e-1)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (7.23e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.79e-1)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (3.97e-2)" 48.2 21.6 14.5 33.6 15.4 30.8 45.9 14.9 18.9 62.4 52.4 101.7 271.3 50.9 30.3 43.0 68.6 569.9 26.1 14.4 15.2 104.0 120.9 81.6 21.1 15.6 15.1 38.8 356.8 78.0 11.9 52.7 15.8 46.3 92.3 30.0 39.2 52.1 17.2 61.0 232.4 52.0 15.7 24.2 108.2 9.7 15.2 23.0 43.6 20.4 24.0 61.3 50.2 16.6 69.6 249.4 3.4 31.0 185.0 158.3 11.3 66.0 101.5 27.1 38.0 37.9 121.7 22.8 414.2 109.5 78.9 104.7 23.8 108.1 27.6 65.2 20.3 35.0 20.5 456.9 131.2 12.5 43.0 95.9 104.8 36.5 87.3 62.9 71.1 11.0 2.0 20.1 74.7 63.8 18.3 22.8 6.1 280.0 34.3 19.4 6.8 28.3 623.2 99.1 5.1 22.9 72.9 99.5 103.8 35.6 33.3 156.3 100.9 49.2 23.8 65.5 37.7 8.2 9.7 1.3 75.8 59.7 34.1 80.4 34.7 29.6 23.1 42.5 17.5 40.6 11.7 17.5 50.6 46.7 2.0 12.5 4.9 9.5 58.7 15.5 14.5 24.2 14.5 15.4 14.9 18.9 14.4 15.2 15.6 15.1 15.8 15.7 15.2 16.6 66.4 205.1 154.8 47.3 27.3 74.2 98.5 148.2 68.9 8.2 36.8 36.4 10.6 2344.8 139.4 84.6 6.2 86.4 27.2 315.1 221.1 1469.8 14.6 257.9 79.0 49.1 18.6 12.6 29.9 344.4 370.1 103.6 196.7 488.8 111.5 24.3 33.9 68.5 227.6 8.4 17.7 193.8 240.1 46.1 80.4 11.2 64.7 54.5 92.5 63.7 87.2 48.7 45.3 17.6 106.0 245.7 268.6 92.2 6.9 55.6 657.1 400.4 230.2 59.9 6.6 27.6 64.6 15.8 3.7 61.3 79.6 439.6 32.5 19.1 174.1 96.9 ANXA7 ANX7 ENSG00000138279 "Annexin A7" P20073 10 73375101-73414076 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 693.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004312, HPA064290" Approved Uncertain Nucleoplasm,Cytosol NA NA 290000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "CAB004312: AB_626681, HPA064290: AB_2685233" "unprognostic (1.48e-1)" "unprognostic (4.70e-2)" "unprognostic (1.90e-1)" "unprognostic (2.23e-1)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (2.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.47e-1)" "unprognostic (2.67e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (6.93e-2)" "unprognostic (3.06e-2)" 79.0 72.1 60.1 58.6 61.1 85.2 75.5 55.9 67.8 69.9 57.1 64.3 39.4 57.6 80.5 69.3 57.0 51.8 113.4 62.6 64.8 116.4 126.0 60.4 60.8 55.4 57.0 67.1 55.9 240.7 55.6 57.2 58.1 69.2 74.4 32.3 70.2 70.6 200.1 61.2 44.9 68.4 60.8 53.4 51.7 26.3 62.5 55.4 83.1 139.6 84.1 75.2 57.4 63.9 143.4 101.4 38.8 95.3 148.9 145.2 84.3 93.2 244.7 119.9 100.6 149.2 164.8 56.6 92.2 177.2 78.8 116.9 73.2 110.9 118.1 140.8 54.5 80.4 46.5 133.9 130.6 115.7 35.4 90.8 105.7 149.2 265.1 104.7 108.0 60.8 106.2 156.4 154.4 114.5 66.1 74.4 43.5 85.1 693.9 53.9 110.1 103.4 209.3 86.5 30.9 42.8 105.1 239.4 90.3 54.3 149.7 61.0 100.8 48.5 87.9 148.1 122.5 100.5 153.2 79.5 114.4 147.4 38.4 188.6 98.1 129.8 57.5 74.9 78.9 96.5 88.8 72.2 101.3 75.1 80.0 71.4 98.0 97.2 77.5 43.2 127.8 137.2 60.1 61.1 55.9 67.8 62.6 64.8 55.4 57.0 58.1 60.8 62.5 63.9 85.0 67.3 61.8 24.8 68.4 86.2 137.9 189.8 40.9 33.0 56.7 40.9 131.9 62.9 120.6 93.8 14.6 210.6 61.2 76.2 193.7 167.2 9.7 82.9 43.8 82.4 191.8 119.3 44.8 150.9 112.0 85.3 51.5 60.4 108.3 69.0 56.4 122.7 119.9 10.1 50.7 82.8 193.3 83.0 87.3 6.5 137.0 91.4 85.4 15.0 301.5 66.4 36.0 26.7 46.2 133.1 47.5 174.5 73.0 125.3 57.9 262.8 161.1 26.3 26.3 82.1 92.9 24.0 42.3 72.5 92.5 177.3 78.4 46.9 76.9 146.1 AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 422.8" "Group enriched" "Detected in many" 4 "Adipocytes: 58.2;Peritubular cells: 74.9;Sertoli cells: 118.3;Smooth muscle cells: 93.0;Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "ASC diff: 307.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" NA NA 240000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" 422.8 48.4 2.6 31.9 3.2 1.4 169.2 2.5 4.2 52.8 2.7 210.8 17.3 95.1 33.5 88.0 84.8 50.7 50.2 2.9 2.5 24.1 19.1 218.6 12.4 2.5 2.5 26.5 12.0 8.4 5.4 28.0 2.6 59.1 41.0 1.7 14.7 103.6 17.8 24.6 57.6 144.8 2.3 21.4 66.6 12.8 2.4 5.9 28.2 22.9 3.9 142.1 50.9 2.5 0.1 1.5 0.2 1.0 307.5 0.3 5.0 0.3 0.1 0.2 0.8 0.9 0.0 0.7 0.7 0.1 0.2 0.5 0.8 0.2 0.8 1.5 5.7 0.4 0.5 18.4 0.8 0.3 1.0 3.3 1.0 0.3 0.8 0.0 0.2 2.2 0.3 1.7 0.6 0.2 0.2 1.4 0.7 0.1 0.4 0.7 0.8 3.0 0.1 2.2 0.3 0.4 0.0 0.2 2.0 2.2 0.1 0.1 0.0 0.3 2.7 1.2 0.4 4.8 5.9 0.6 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 3.2 2.5 4.2 2.9 2.5 2.5 2.5 2.6 2.3 2.4 2.5 58.2 3.2 6.0 0.0 0.5 2.9 0.1 0.0 2.2 0.0 1.1 2.2 9.5 0.0 1.9 0.0 0.0 0.1 0.4 0.1 0.0 0.2 4.5 0.8 2.3 12.3 0.0 0.0 0.4 0.2 0.1 11.3 0.0 1.4 1.3 2.1 20.7 0.2 1.4 0.0 0.3 0.1 0.0 1.4 2.7 2.6 3.4 0.9 3.6 3.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 74.9 0.0 0.4 0.1 1.4 1.0 0.4 118.3 2.6 93.0 1.1 1.3 0.7 1.8 0.3 0.6 74.6 0.1 0.3 AP2B1 "ADTB2, CLAPB1" ENSG00000006125 "Adaptor related protein complex 2 subunit beta 1" P63010 17 35578046-35726413 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 503.9;Late spermatids: 739.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017631, HPA056733, HPA067983" Approved Supported Vesicles NA NA 380000 "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB017631: AB_2058201, HPA056733: AB_2683219, HPA067983: AB_2732777" "unprognostic (1.49e-2)" "unprognostic (4.04e-3)" "unprognostic (2.15e-3)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-2)" "unprognostic (1.51e-3)" "unprognostic (2.64e-2)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.58e-2)" "unprognostic (2.50e-1)" "prognostic favorable (2.62e-4)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-2)" 46.4 42.4 77.0 38.2 87.8 49.2 58.3 69.9 88.7 54.1 76.6 67.6 33.5 41.7 70.7 25.1 46.7 42.3 67.6 92.1 83.5 69.0 35.0 53.4 38.6 69.8 78.6 57.2 33.2 126.4 55.0 66.8 76.8 40.9 84.0 76.1 41.9 50.1 57.5 29.9 38.8 56.0 80.3 42.0 48.4 93.5 78.7 59.7 65.1 61.0 45.5 46.8 34.4 95.0 188.8 233.9 113.7 132.0 184.4 202.8 51.6 94.3 138.9 131.0 141.1 129.0 154.6 90.5 81.1 175.3 168.8 173.2 162.5 264.8 190.8 108.6 147.0 117.7 161.8 71.0 104.7 119.3 80.8 128.9 104.3 134.5 209.3 151.2 211.4 111.8 190.6 126.9 206.9 36.9 113.7 58.7 94.2 98.9 164.5 94.3 165.1 64.7 166.2 108.3 94.4 114.1 114.5 39.6 126.9 273.3 161.5 78.5 211.5 99.3 93.4 109.8 142.1 53.0 106.1 84.7 124.1 86.9 112.5 19.6 11.8 16.7 16.0 15.3 16.9 12.1 13.9 14.3 10.7 11.9 6.3 8.0 13.3 9.6 16.8 10.7 20.5 11.0 77.0 87.8 69.9 88.7 92.1 83.5 69.8 78.6 76.8 80.3 78.7 95.0 76.5 16.0 17.0 49.3 45.9 31.1 26.3 57.4 70.6 67.6 88.9 50.9 62.5 68.6 37.4 112.2 56.3 29.7 70.7 97.4 117.4 105.0 503.9 74.5 83.7 56.8 71.3 214.7 105.5 120.2 42.8 47.1 36.2 85.4 41.2 46.5 79.9 64.5 44.1 69.0 109.8 79.4 28.5 54.3 25.9 739.2 58.7 37.2 16.0 60.0 47.3 52.6 74.2 81.4 89.0 177.9 46.6 68.4 32.1 37.4 39.4 102.5 30.4 40.9 59.2 25.3 37.6 258.8 60.0 19.6 14.6 32.8 49.2 37.3 89.8 29.1 APAF1 "APAF-1, CED4" ENSG00000120868 "Apoptotic peptidase activating factor 1" O14727 12 98645290-98735433 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32.0" "Cell type enhanced" "Detected in many" "monocytes: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 71.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031373, CAB069399" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB069399: AB_1611908, HPA031373: AB_10602230" "unprognostic (1.32e-1)" "unprognostic (5.12e-2)" "prognostic favorable (5.90e-4)" "unprognostic (2.21e-1)" "unprognostic (3.94e-1)" "unprognostic (8.21e-3)" "unprognostic (2.03e-3)" "unprognostic (1.35e-1)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (5.63e-2)" "unprognostic (6.04e-2)" "unprognostic (9.93e-3)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (3.53e-2)" "unprognostic (3.07e-2)" 4.5 2.8 2.4 8.9 2.8 32.0 5.0 2.5 2.7 5.5 1.2 8.5 5.1 5.5 3.5 3.2 4.0 7.3 2.6 2.8 1.3 3.7 4.7 6.7 9.4 2.3 1.2 7.7 4.0 2.8 3.1 7.6 2.2 3.9 9.6 5.8 4.6 3.4 3.4 5.7 7.1 5.0 1.9 9.7 6.6 3.1 2.2 7.7 4.7 3.1 8.8 5.8 3.9 4.3 6.8 8.7 30.3 11.6 9.4 18.2 8.3 17.3 12.1 11.7 11.6 6.3 4.8 9.8 4.5 12.7 4.4 11.3 20.2 11.4 13.9 7.3 8.0 18.5 9.6 7.7 3.5 18.6 22.7 7.5 3.5 12.1 5.5 14.1 19.6 7.3 9.1 5.2 18.7 1.8 9.4 19.0 8.1 7.5 5.8 11.9 22.8 3.1 7.1 11.5 4.1 7.4 13.5 5.3 4.6 18.6 9.2 25.7 17.7 7.5 6.6 9.0 5.4 3.5 7.1 11.5 3.3 25.4 11.5 16.8 18.1 17.0 4.0 8.0 3.1 5.5 2.8 2.3 14.3 6.2 2.9 1.9 71.1 2.9 8.5 10.4 2.1 3.9 2.4 2.8 2.5 2.7 2.8 1.3 2.3 1.2 2.2 1.9 2.2 4.3 11.7 12.8 8.2 10.4 13.8 3.8 5.7 8.7 8.6 5.8 6.4 6.5 1.5 1.5 7.8 7.3 14.6 3.8 21.4 22.3 0.0 9.4 0.7 5.9 11.6 11.1 12.0 7.6 12.8 8.0 8.0 9.1 14.8 8.7 6.3 18.6 13.2 6.7 12.3 5.0 13.8 18.9 4.1 34.7 25.3 1.3 5.9 34.1 10.6 30.9 54.6 2.7 20.6 14.1 11.2 19.7 20.3 5.3 8.9 8.7 9.2 2.7 8.9 9.8 0.0 6.9 8.1 6.9 10.0 8.7 3.3 1.9 14.6 4.3 13.3 15.0 APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC regulator of WNT signaling pathway" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.8" "Cell type enhanced" "Detected in many" "Astrocytes: 536.4;Bipolar cells: 196.9;Excitatory neurons: 165.8;Inhibitory neurons: 236.4;Oligodendrocyte precursor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA013349: AB_1844913, HPA013362: " "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 6.9 4.6 28.4 6.2 26.0 9.1 5.7 23.1 31.0 5.7 0.1 6.7 6.2 5.6 3.3 7.7 4.3 4.9 7.2 52.8 27.4 6.2 5.7 6.2 5.6 32.1 30.7 6.6 4.1 8.5 3.9 5.1 39.0 5.2 6.2 20.0 3.8 4.1 8.5 5.7 8.5 7.5 16.0 6.1 5.0 5.1 37.9 8.5 5.9 11.8 5.9 5.4 3.6 20.9 11.3 10.1 16.8 12.2 13.4 11.3 6.7 17.9 8.5 9.7 11.5 8.2 8.9 22.0 17.0 23.1 15.5 9.0 17.4 14.6 15.9 13.2 12.2 16.8 14.9 6.2 6.6 8.4 8.6 9.3 9.8 16.6 10.8 6.8 13.6 10.2 20.9 7.2 14.3 7.8 9.6 4.2 6.0 6.1 3.6 8.1 20.8 10.7 8.9 14.1 17.0 10.1 16.9 6.5 7.1 6.8 9.1 6.7 22.8 19.6 9.5 19.5 13.6 5.6 9.5 8.2 10.8 15.3 11.2 11.8 2.5 4.9 2.9 1.3 2.4 2.8 1.5 1.9 2.1 3.1 2.4 2.4 11.4 2.9 2.4 2.7 1.5 1.0 28.4 26.0 23.1 31.0 52.8 27.4 32.1 30.7 39.0 16.0 37.9 20.9 40.6 51.3 23.6 536.4 21.9 11.2 8.9 10.1 19.9 196.9 13.1 14.9 56.6 18.6 20.1 0.0 66.7 5.4 28.9 28.6 0.0 18.7 10.5 20.1 27.6 31.2 27.5 17.4 165.8 19.5 6.5 25.9 19.4 29.7 19.0 28.7 26.7 13.9 16.3 79.1 236.4 17.2 2.0 18.9 12.4 5.5 17.7 27.8 17.8 85.3 30.7 23.4 23.7 196.6 150.8 20.3 34.7 19.5 22.9 10.4 37.2 5.1 18.0 41.5 39.5 44.1 34.0 19.2 30.4 26.5 11.6 2.9 22.4 27.1 16.0 8.9 APEX1 "APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1" ENSG00000100823 "Apurinic/apyrimidinic endodeoxyribonuclease 1" P27695 14 20455191-20457772 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000956, HPA002564, CAB004294, CAB047307" Supported Supported Nucleoplasm Yes No 330000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Nucleoplasm "CAB004294: AB_626685, CAB047307: , HPA000956: AB_2666158, HPA002564: AB_1078174" "unprognostic (2.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.55e-2)" "unprognostic (4.74e-3)" "unprognostic (1.97e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.82e-5)" "unprognostic (4.21e-2)" "unprognostic (3.14e-2)" "unprognostic (2.46e-2)" "unprognostic (2.42e-2)" "unprognostic (1.68e-1)" "unprognostic (1.38e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-2)" "unprognostic (2.54e-1)" "unprognostic (7.08e-2)" 83.9 103.6 56.9 82.8 58.1 154.9 103.2 60.0 67.5 80.4 57.9 89.1 107.5 97.2 66.5 80.5 99.1 79.7 76.6 57.5 60.3 82.8 104.6 61.0 112.4 58.9 58.3 146.3 92.2 88.3 39.3 57.3 59.5 69.3 92.7 52.9 66.0 80.2 102.9 83.4 73.0 95.7 59.5 68.9 85.4 21.5 60.1 125.0 93.2 71.9 121.2 103.8 65.8 62.6 249.3 296.8 267.8 247.2 180.9 259.3 226.5 227.3 245.7 333.3 287.4 216.9 240.7 477.9 198.4 176.4 178.1 262.5 317.5 242.1 304.8 214.7 135.9 195.5 162.8 368.9 189.5 623.1 193.2 270.6 261.6 217.6 212.6 267.2 282.3 193.9 228.4 153.6 270.7 240.0 404.7 264.7 260.3 282.4 269.5 441.5 297.7 200.8 281.7 327.1 315.2 201.8 248.5 305.2 253.1 185.0 186.4 276.7 186.0 175.0 292.8 177.9 216.6 203.1 375.8 327.7 77.8 390.7 224.7 0.9 106.7 7.5 79.6 93.4 108.4 154.8 98.9 95.4 208.6 140.5 133.1 117.7 6.8 97.6 60.1 235.6 65.8 200.3 56.9 58.1 60.0 67.5 57.5 60.3 58.9 58.3 59.5 59.5 60.1 62.6 63.8 64.1 57.6 11.8 120.3 106.4 101.1 192.9 136.1 57.5 131.3 136.8 50.1 111.5 117.1 68.0 41.7 200.1 114.1 32.4 150.6 152.7 19.9 65.0 161.1 75.6 120.0 135.6 20.6 104.5 212.6 88.7 72.9 82.0 81.6 165.5 42.1 70.8 175.6 28.6 19.5 85.4 138.4 96.7 89.4 5.8 80.5 95.2 64.0 11.2 121.9 77.4 75.2 22.6 19.4 78.2 73.1 64.3 71.1 60.4 66.2 170.1 64.6 51.6 52.6 87.5 174.2 8.5 43.0 106.4 97.0 101.5 75.1 198.4 157.6 76.8 APOA1 ENSG00000118137 "Apolipoprotein A1" P02647 11 116835751-116837622 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Amyloidosis, Atherosclerosis, Cancer-related genes, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 19248.5" "Group enriched" "Detected in many" 21 "Hepatocytes: 27332.1;Proximal enterocytes: 18348.1" "Cancer enriched" "Detected in many" 48 "liver cancer: 4515.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 17 "Hep G2: 3460.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016778, HPA046715" Supported Approved Vesicles,Cytosol "Secreted to blood" NA NA 1450000000000 110000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "CAB016778: , HPA046715: AB_2679768" "unprognostic (1.88e-3)" "unprognostic (4.53e-2)" "unprognostic (7.46e-2)" "unprognostic (4.00e-3)" "unprognostic (3.70e-2)" "unprognostic (1.41e-1)" "prognostic favorable (5.05e-4)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (9.60e-3)" "unprognostic (1.59e-3)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.67e-8)" "unprognostic (3.46e-3)" "unprognostic (1.15e-1)" "unprognostic (6.24e-2)" "unprognostic (9.54e-2)" 3.2 1.4 1.2 3.6 1.2 0.0 2.1 1.1 1.4 0.8 0.8 7.4 1709.3 3.5 0.4 1.1 6.1 1.7 67.2 1.0 1.1 3.7 19248.5 2.7 3.2 1.1 1.1 23.1 2.5 0.0 4.2 1.6 1.1 1.1 0.2 0.1 0.7 1.0 0.8 1.0 4053.7 2.1 1.1 9.0 14.6 384.5 1.2 0.9 3.7 0.2 0.1 0.5 1.5 1.2 0.0 0.0 0.6 0.1 0.0 0.0 15.0 0.0 0.0 0.0 0.0 203.4 0.3 3.1 6.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.1 7.3 1.9 3460.4 0.0 16.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.0 0.2 0.3 15.0 1.2 1.2 0.1 0.5 15.0 20.3 0.0 2.6 5.7 20.7 8.9 0.0 0.0 3.9 0.0 0.1 2.6 0.0 0.4 2.1 0.1 1.2 0.2 4.9 0.0 5.5 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.2 0.1 0.2 0.5 0.0 0.2 0.0 1.2 0.6 0.1 1.2 1.2 1.1 1.4 1.0 1.1 1.1 1.1 1.1 1.1 1.2 1.2 2.0 3.2 3.3 0.3 49.7 0.1 0.5 0.2 0.6 0.5 0.9 0.9 37.0 479.0 1.3 0.0 0.0 0.6 5.1 0.4 0.0 0.1 36.9 15.2 4.3 50.3 1.8 541.9 0.5 1.1 4.2 5.8 17.9 1.7 2.5 419.2 458.7 27332.1 3.3 0.0 0.8 458.8 0.0 681.2 2.0 149.7 22.4 2.1 0.0 0.0 0.0 0.3 3.1 0.0 0.3 0.3 458.2 4.9 1.0 0.1 18348.1 9.0 0.4 0.6 6.6 1.6 13.0 39.8 11.2 0.0 0.6 4.2 35.7 1051.7 175.7 0.3 APOA2 ENSG00000158874 "Apolipoprotein A2" P02652 1 161222292-161223631 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1388 "liver: 36012.6" "Cell type enriched" "Detected in some" 75 "Hepatocytes: 50065.8" "Cancer enriched" "Detected in many" 329 "liver cancer: 11230.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "Hep G2: 16822.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025885, HPA072575" Supported "Secreted to blood" NA NA 115000000000 92000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB025885: , HPA072575: " "unprognostic (2.05e-1)" "unprognostic (4.70e-2)" "unprognostic (1.12e-1)" "unprognostic (2.99e-1)" "unprognostic (9.82e-2)" "unprognostic (1.92e-1)" "unprognostic (3.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (4.40e-3)" "unprognostic (3.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.60e-1)" "unprognostic (6.09e-2)" 3.8 1.1 0.7 0.7 0.6 25.9 1.8 0.5 1.4 0.9 1.0 0.7 0.0 0.7 0.1 1.0 1.9 0.0 2.0 0.6 0.8 9.5 36012.6 2.1 0.3 1.1 0.8 0.7 2.0 0.0 1.2 1.3 1.1 0.6 0.5 0.0 0.6 0.0 0.6 0.9 0.9 0.0 0.8 7.7 1.9 1.2 0.7 0.4 0.8 0.0 0.3 0.4 0.8 1.0 0.0 0.6 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 1814.4 0.0 3.6 0.0 0.0 0.0 2.3 1.5 0.0 0.0 0.0 0.0 5.8 10.0 16822.4 0.0 19.3 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.7 0.7 1.5 0.0 1.1 1.3 14.6 0.3 0.0 11.3 0.8 0.0 7.8 0.0 0.2 5.2 0.1 0.0 4.1 0.0 0.1 0.0 0.0 3.8 0.0 5.2 0.0 6.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 0.0 0.7 0.6 0.5 1.4 0.6 0.8 1.1 0.8 1.1 0.8 0.7 1.0 0.0 0.0 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 480.4 0.0 0.0 0.0 0.8 0.0 0.1 1.9 0.0 1.7 0.0 0.0 22.5 0.0 323.6 0.0 0.6 6.4 0.2 0.0 0.0 0.0 0.0 425.9 50065.8 4.7 0.0 0.0 0.2 0.0 665.8 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 9.8 0.0 0.0 0.0 0.0 0.0 1.9 0.9 0.0 0.0 5.6 26.0 0.0 0.0 0.0 APOBEC3B "FLJ21201, PHRBNL" ENSG00000179750 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3B" Q9UH17 22 38982347-38992804 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.4;intestine: 12.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 11.8;Ductal cells: 14.7;Erythroid cells: 14.1;Plasma cells: 26.2;Urothelial cells: 11.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 256.0;Karpas-707: 283.6" "HPA056980, HPA066719" Approved Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (2.92e-2)" "prognostic favorable (2.58e-5)" "unprognostic (4.29e-2)" "unprognostic (1.19e-1)" "unprognostic (2.50e-1)" "unprognostic (1.35e-1)" "unprognostic (1.69e-2)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.47e-2)" "unprognostic (2.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.04e-1)" 0.9 1.2 0.1 5.7 0.1 28.4 2.0 0.1 0.2 1.2 0.1 12.1 7.3 1.0 0.4 3.0 0.7 1.1 0.8 0.1 0.1 2.7 1.1 1.9 5.9 0.1 0.1 0.7 3.3 1.2 0.2 1.6 0.1 0.4 12.0 0.3 2.8 0.2 0.4 2.1 4.3 1.4 0.1 6.4 4.1 0.3 0.2 2.5 1.3 0.2 8.6 7.6 1.5 0.2 256.0 28.0 10.5 68.1 1.5 6.0 18.6 23.0 19.7 43.0 56.5 54.7 46.6 3.0 20.4 22.9 63.0 108.2 1.3 4.5 43.1 92.1 2.5 72.5 5.6 14.0 0.7 61.7 43.0 2.3 0.5 45.1 2.2 8.9 17.0 0.0 41.6 283.6 68.1 6.9 0.2 35.3 0.3 24.6 25.2 1.8 105.0 95.6 9.1 42.2 1.8 0.0 0.0 0.3 16.0 1.8 33.0 18.1 10.2 48.0 81.9 7.5 0.7 62.8 18.0 0.3 34.4 68.2 100.7 0.4 1.0 0.0 0.2 4.9 0.0 7.2 0.5 0.3 0.6 3.1 0.0 0.3 1.4 1.7 1.7 0.0 2.8 3.5 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.0 1.7 0.0 2.2 5.4 3.2 11.8 0.6 0.0 1.5 0.5 0.3 0.0 8.1 0.0 0.0 1.0 0.4 4.6 0.0 14.7 0.0 5.9 0.6 0.2 0.0 14.1 0.0 1.8 1.8 0.8 3.1 5.3 0.0 0.8 0.4 0.0 2.1 0.0 0.0 0.4 10.2 1.2 6.3 0.0 0.0 2.3 7.2 0.0 1.4 0.0 0.0 0.0 0.0 6.0 9.9 0.0 26.2 1.4 0.4 0.3 9.3 0.0 0.0 0.0 0.9 0.0 0.0 4.2 3.3 0.8 0.5 0.1 1.6 11.4 APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 16232.1" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 33405.9" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 5.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "Hep G2: 576.4;HSkMC: 332.9;K-562: 151.6;SK-MEL-30: 268.0" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" NA NA 20300000000 15000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" 59.2 1998.1 90.3 28.1 133.0 52.2 87.1 83.3 338.1 29.0 73.6 29.1 13.1 11.0 42.0 5.9 21.2 31.0 10.9 75.3 109.8 14.6 16232.1 289.9 140.1 133.2 152.8 56.4 21.4 16.3 23.6 41.7 121.9 14.4 16.7 15.1 35.5 2.2 22.2 73.1 49.1 4.0 92.7 254.9 22.7 18.7 139.2 37.4 36.3 6.1 33.9 23.5 11.3 169.4 2.7 26.5 12.0 5.0 37.1 38.2 111.5 1.3 1.7 4.8 7.3 55.6 49.9 8.4 9.4 1.0 3.2 1.8 15.6 1.9 2.3 0.4 63.5 36.8 4.2 576.4 32.9 27.5 18.1 332.9 2.8 4.8 1.8 9.2 1.3 1.8 151.6 0.8 1.7 3.6 1.5 2.0 112.4 10.4 5.6 6.2 16.0 0.8 7.3 2.0 5.3 3.3 18.9 0.3 268.0 37.7 2.2 98.4 4.2 0.4 1.7 0.2 1.7 4.5 5.4 8.2 0.7 7.4 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.3 90.3 133.0 83.3 338.1 75.3 109.8 133.2 152.8 121.9 92.7 139.2 169.4 22.9 115.4 214.4 2.3 40.6 17.0 4.1 5.8 6.2 2.5 49.8 92.8 0.8 453.2 55.8 1.8 0.0 31.7 1.6 2.4 49.0 4.6 1.2 6.6 128.4 68.9 2.4 768.8 0.3 4.0 341.3 93.0 19.4 5.0 142.6 30.6 432.6 33405.9 4789.8 0.0 0.5 3.2 4.1 867.7 27.3 22.8 270.9 620.5 30.2 3.7 124.5 276.0 0.0 0.0 0.0 3.2 0.3 259.5 1.3 4.2 0.6 16.6 24.4 9.9 19.7 1628.8 24.4 2.0 3.2 3.7 17.8 71.6 46.7 1226.7 2.1 5.0 APOC3 ENSG00000110245 "Apolipoprotein C3" P02656 11 116829706-116833072 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 27649.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 84691.9" "Cancer enriched" "Detected in many" 643 "liver cancer: 4021.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "CACO-2: 107.3;Hep G2: 296.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA065365, HPA073918" Supported Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Secreted to blood" NA NA 106000000000 45000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nucleoli, Cell Junctions" "HPA065365: AB_2732733, HPA073918: " "prognostic favorable (3.77e-4)" "unprognostic (2.33e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.60e-2)" "unprognostic (5.21e-2)" 4.1 1.2 0.0 1.0 0.0 0.0 2.5 0.0 0.1 0.4 0.0 7.2 907.0 0.5 0.0 1.1 1.9 0.0 1.6 0.0 0.0 18.2 27649.0 1.4 0.9 0.0 0.0 0.8 2.4 0.0 0.8 0.9 0.0 0.6 0.0 0.0 0.6 0.0 0.6 1.2 1106.7 0.5 0.0 8.0 1.5 1.0 0.0 0.5 0.8 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.0 0.1 107.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 296.2 0.0 10.7 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 2.3 0.2 0.0 0.0 0.0 6.3 3.9 0.0 0.1 1.1 3.8 4.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 67.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 674.9 0.0 0.0 0.0 0.2 0.0 0.0 3.9 0.0 4.2 0.0 0.0 39.7 0.0 823.7 0.0 0.4 1.5 0.1 0.0 0.0 0.0 0.3 707.9 84691.9 1.1 0.0 0.0 264.5 0.0 1107.4 0.0 12.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.0 0.0 0.0 0.0 10473.3 121.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 39.8 0.0 135.5 0.0 APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4485.3;Leydig cells: 2077.4;Melanocytes: 1028.1;Peritubular cells: 994.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 6 "ASC diff: 3507.4;ASC TERT1: 1918.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" 2071.8 84.8 949.6 13.9 1157.3 0.9 5037.8 1174.9 1364.1 620.2 1370.1 144.7 56.0 496.7 155.7 160.0 750.6 213.3 1007.8 952.8 1010.4 49.7 7.1 183.5 24.6 1148.3 1040.5 131.2 212.4 61.9 192.2 350.5 1122.0 419.8 57.2 0.8 1272.3 183.8 1154.9 970.1 88.4 96.2 1027.5 8.2 402.6 75.7 1070.2 113.5 828.8 625.3 20.8 434.4 591.7 1347.6 0.0 2.2 0.5 0.7 3507.4 1918.1 6.1 31.3 7.6 0.1 0.2 222.4 0.4 0.4 0.9 1.8 0.0 0.9 0.4 10.5 0.3 0.3 2.4 0.3 0.2 0.1 12.5 0.3 0.5 91.4 21.0 0.2 17.0 0.3 4.3 0.2 0.2 0.9 5.3 1.3 0.1 0.7 0.5 38.9 0.5 0.1 0.0 0.6 0.0 2.8 0.7 0.5 0.0 34.8 31.8 1.3 67.2 0.1 0.4 0.5 1.4 0.4 0.1 0.2 0.3 9.2 1.0 0.4 420.3 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 949.6 1157.3 1174.9 1364.1 952.8 1010.4 1148.3 1040.5 1122.0 1027.5 1070.2 1347.6 543.2 0.0 11.0 2.9 7.5 145.0 16.0 25.4 46.7 0.0 121.6 138.7 26.9 1.5 81.8 5.5 0.0 5.4 15.9 1.4 0.0 0.4 9.7 16.3 393.7 114.1 46.3 0.0 3.3 0.0 4.2 4485.3 7.7 7.0 0.0 0.0 21.4 0.0 13.3 0.0 2.1 0.7 10.2 0.3 193.2 51.0 2077.4 31.8 1028.1 279.2 1.0 0.0 0.0 300.6 221.5 2.3 0.3 994.5 19.2 25.7 0.0 0.2 128.9 0.0 19.7 100.3 210.7 10.5 4.0 24.1 102.6 5.9 23.5 7.0 0.6 47.3 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 APOL2 APOL-II ENSG00000128335 "Apolipoprotein L2" Q9BQE5 22 36226209-36239954 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 80.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA001078, CAB026695" Supported NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "CAB026695: , HPA001078: AB_10602432" "unprognostic (4.19e-2)" "unprognostic (1.58e-1)" "unprognostic (1.50e-2)" "unprognostic (4.26e-3)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.38e-2)" "unprognostic (7.39e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.22e-7)" "unprognostic (1.80e-1)" "unprognostic (6.79e-2)" "unprognostic (2.66e-2)" "prognostic favorable (5.06e-6)" 42.0 23.4 36.5 43.6 38.3 13.0 37.4 37.0 49.7 36.8 34.9 28.8 41.8 33.1 17.8 18.4 30.2 42.1 40.0 38.6 43.2 52.6 65.4 44.8 42.5 52.0 41.6 19.5 15.3 19.7 47.3 22.3 52.3 34.2 26.5 12.2 25.0 28.3 28.0 16.2 32.3 35.8 42.1 46.6 38.3 6.8 38.2 29.6 19.4 18.3 30.4 59.5 26.1 38.2 24.0 18.7 17.0 12.7 63.6 49.1 31.7 32.1 73.4 84.1 113.3 7.1 19.2 29.3 52.4 57.2 52.0 11.1 18.3 25.4 41.6 98.0 21.3 13.4 39.9 33.5 107.3 29.0 25.2 62.4 17.0 59.2 15.5 35.2 55.8 16.4 24.8 79.1 53.2 9.4 29.8 13.2 6.3 8.6 16.4 30.3 21.6 17.3 85.6 63.3 30.2 8.5 21.8 40.7 18.4 11.5 12.8 4.1 54.8 50.6 25.1 10.6 17.9 47.6 25.8 9.1 43.7 15.0 19.6 31.1 22.8 16.8 39.7 46.6 36.3 16.3 28.6 33.2 16.5 10.3 16.2 27.1 116.5 28.4 34.0 10.2 29.2 14.3 36.5 38.3 37.0 49.7 38.6 43.2 52.0 41.6 52.3 42.1 38.2 38.2 14.8 35.3 16.8 8.5 12.5 6.0 8.0 21.4 0.6 5.0 7.5 5.0 24.3 21.5 20.1 12.9 0.0 16.6 17.1 31.8 17.6 42.6 0.2 53.0 21.1 21.2 4.8 8.6 18.1 62.9 10.7 19.5 21.4 80.2 2.5 8.3 18.9 65.4 24.2 6.7 9.3 12.0 22.4 20.9 13.0 1.9 16.8 15.0 8.8 7.5 26.6 9.3 25.7 12.1 4.8 68.1 14.5 20.7 17.9 28.4 33.1 25.6 15.6 5.1 0.0 23.9 12.4 0.4 0.2 2.8 6.7 15.2 19.1 10.4 8.0 19.4 APPBP2 "Hs.84084, KIAA0228, PAT1" ENSG00000062725 "Amyloid beta precursor protein binding protein 2" Q92624 17 60443158-60526242 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 391.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 110.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066852, HPA078370" Supported Supported Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 21: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA066852: , HPA078370: " "unprognostic (1.43e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-3)" "unprognostic (2.97e-2)" "unprognostic (2.93e-2)" "unprognostic (4.53e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (7.67e-2)" "unprognostic (9.24e-2)" "unprognostic (2.39e-1)" "unprognostic (2.90e-3)" "unprognostic (6.87e-2)" "unprognostic (5.07e-2)" "unprognostic (1.03e-1)" "unprognostic (3.84e-1)" "unprognostic (1.31e-1)" "unprognostic (9.36e-2)" 14.9 11.2 13.6 10.2 15.3 4.1 11.3 14.9 15.4 11.7 11.9 10.4 7.3 12.8 9.5 10.3 10.0 11.6 7.0 12.0 14.1 13.1 11.0 9.5 8.7 12.6 13.6 19.6 11.5 14.4 8.0 12.2 13.8 13.7 9.1 17.3 8.5 10.1 9.4 8.7 7.2 11.8 14.6 12.0 10.8 23.5 14.4 10.3 12.8 9.8 8.2 10.0 8.8 22.0 16.5 21.9 22.6 19.0 23.7 24.7 12.6 25.4 17.5 13.9 17.6 10.7 14.0 17.0 41.7 21.4 24.0 13.8 16.2 8.8 24.4 15.3 12.4 21.6 20.1 22.5 25.2 18.1 23.1 24.4 11.4 14.6 14.1 21.6 21.9 10.5 16.5 19.3 20.4 110.4 25.5 9.2 5.0 17.9 9.7 16.8 37.8 20.0 21.5 26.7 24.6 21.0 22.0 3.7 18.2 12.5 30.4 12.3 28.4 31.1 37.6 21.7 19.5 20.5 70.8 14.3 20.6 10.5 22.4 13.8 9.5 12.0 7.4 7.1 8.4 7.2 8.7 8.2 9.3 9.7 11.8 8.9 11.9 12.5 12.2 5.6 9.3 7.5 13.6 15.3 14.9 15.4 12.0 14.1 12.6 13.6 13.8 14.6 14.4 22.0 32.8 28.9 24.0 55.5 20.9 18.0 15.6 18.6 21.6 59.4 18.8 15.0 27.3 20.0 20.8 14.7 18.8 27.4 24.0 17.0 19.6 19.7 391.3 21.3 33.6 29.3 33.0 5.9 57.8 16.6 8.9 30.1 13.7 27.3 22.9 40.6 40.0 21.7 19.8 37.0 65.4 22.1 20.3 19.4 14.9 126.2 35.4 17.7 17.8 44.0 22.5 44.4 16.5 55.8 132.0 16.9 13.2 39.1 17.1 24.7 15.9 30.2 19.5 34.9 39.5 32.1 31.6 56.3 33.3 15.3 18.5 63.2 20.8 42.0 20.4 18.1 AR "AIS, DHTR, HUMARA, NR3C4, SBMA, SMAX1" ENSG00000169083 "Androgen receptor" P10275 X 67544021-67730619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 93.7;Granulosa cells: 104.8;Hepatocytes: 269.2;Leydig cells: 77.9;Peritubular cells: 86.5;Skeletal myocytes: 75.0" "Cancer enhanced" "Detected in many" "breast cancer: 15.6;prostate cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.3;BJ hTERT+: 10.3;HAP1: 14.9;LHCN-M2: 16.1;RH-30: 23.6;T-47d: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000001, HPA004733, CAB065764" Enhanced Supported Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Cytosol "CAB000001: AB_2060174, CAB065764: AB_10620739, HPA004733: " "unprognostic (1.34e-1)" "unprognostic (8.10e-3)" "unprognostic (2.49e-2)" "unprognostic (5.95e-2)" "unprognostic (1.04e-2)" "unprognostic (3.35e-2)" "prognostic favorable (8.77e-4)" "unprognostic (4.99e-2)" "unprognostic (1.72e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "prognostic favorable (1.03e-8)" "unprognostic (8.23e-3)" "unprognostic (8.90e-2)" "unprognostic (4.23e-2)" "unprognostic (7.97e-2)" 6.7 1.0 1.1 0.5 1.3 0.0 8.7 1.7 1.1 23.6 0.2 2.0 0.2 18.6 16.1 1.2 20.7 2.0 5.8 1.0 3.5 3.6 38.2 1.5 0.3 3.5 2.6 14.6 0.8 0.1 1.9 0.1 2.7 16.5 0.6 0.2 1.4 18.2 13.9 5.2 0.9 9.5 2.1 1.3 1.5 3.9 4.8 2.7 2.1 6.1 0.5 3.5 12.9 2.0 0.0 4.8 13.3 0.0 0.0 0.0 0.0 7.3 10.3 0.3 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 14.9 0.0 0.0 0.0 2.4 0.0 1.5 0.0 0.8 0.0 0.0 5.5 0.0 1.8 0.0 0.0 3.9 0.1 4.6 2.2 16.1 1.5 0.0 0.0 5.4 0.0 0.0 0.0 23.6 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 10.9 7.6 0.3 0.3 2.2 0.0 3.5 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.7 1.1 1.0 3.5 3.5 2.6 2.7 2.1 4.8 2.0 3.1 0.0 5.0 28.4 0.4 9.7 17.8 0.2 15.9 0.7 93.7 33.7 37.4 14.3 10.7 3.7 0.0 3.5 14.0 0.0 1.9 11.3 1.1 2.9 49.1 10.5 0.0 5.3 7.7 0.0 0.2 39.4 0.0 5.8 1.3 104.8 36.0 269.2 0.8 0.0 17.8 0.3 0.0 2.2 4.2 4.4 77.9 3.3 10.6 1.0 1.7 0.2 0.0 26.7 0.2 0.6 0.0 86.5 0.0 36.5 0.6 27.7 3.6 0.3 65.7 75.0 20.8 0.8 3.3 12.7 16.1 1.0 1.7 37.8 0.2 22.0 AREG "AREGB, SDGF" ENSG00000109321 Amphiregulin P15514 4 74445136-74455005 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 129.9;placenta: 328.8;urinary bladder: 145.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1119.1;Basal prostatic cells: 1254.3;Macrophages: 1271.1;Paneth cells: 909.8;Urothelial cells: 2102.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 67.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "basophil: 11.0;eosinophil: 11.8;NK-cell: 3.8" "Group enriched" "Detected in many" 10 "granulocytes: 11.8;NK-cells: 3.8" "Cell line enhanced" "Detected in many" "CACO-2: 379.0;HBEC3-KT: 648.1;hTCEpi: 644.0;hTERT-HME1: 1365.7;MCF7: 416.8" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.2" "Low region specificity" "Detected in many" "HPA008720, CAB023519" Approved Approved Mitochondria NA NA 1520000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB023519: AB_2060673, HPA008720: AB_1844978" "unprognostic (1.44e-2)" "unprognostic (1.84e-3)" "unprognostic (3.36e-2)" "unprognostic (2.26e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.90e-1)" "unprognostic (8.06e-2)" "prognostic unfavorable (8.32e-5)" "unprognostic (2.56e-2)" "unprognostic (2.49e-3)" "unprognostic (2.40e-2)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (6.83e-3)" 48.1 4.6 0.1 36.7 0.1 129.9 61.6 0.1 0.8 19.2 1.8 18.7 3.3 3.7 0.2 43.4 13.2 74.1 20.5 0.3 0.1 2.5 4.0 36.1 1.9 0.3 0.2 12.4 4.5 1.5 9.5 328.8 0.8 6.5 18.9 0.1 11.7 0.7 18.4 15.3 10.2 6.5 0.2 10.0 20.2 9.3 0.4 7.1 5.4 0.8 3.0 145.6 13.8 0.4 15.9 107.3 0.0 0.0 0.9 1.4 0.0 3.2 5.0 0.7 2.9 379.0 59.8 0.0 8.0 0.0 0.0 17.4 0.1 648.1 6.5 0.1 0.0 0.4 2.8 18.0 191.9 2.3 0.4 5.9 644.0 37.8 1365.7 0.9 0.2 0.4 1.6 0.7 14.4 416.8 0.2 0.0 0.0 78.6 42.8 0.0 0.1 0.1 36.4 2.9 0.5 0.2 22.2 1.2 0.0 0.4 11.6 0.1 1.0 0.0 15.3 5.3 0.1 0.9 0.0 0.1 0.0 0.0 1.7 11.0 0.0 11.8 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.3 0.2 0.0 0.1 3.8 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.8 0.3 0.1 0.3 0.2 0.8 0.2 0.4 0.4 670.0 198.7 301.9 0.0 190.7 1119.1 1254.3 73.0 303.9 0.0 801.5 460.2 49.0 62.9 183.9 51.5 0.0 1.8 836.1 878.0 0.0 61.8 70.4 167.7 12.3 32.2 41.6 18.5 0.0 10.2 1.5 80.8 254.9 193.1 680.5 0.9 10.8 4.2 32.2 0.0 0.5 393.5 8.2 250.4 196.4 12.1 0.3 1271.1 33.8 0.0 1.7 0.8 20.6 0.0 0.0 497.1 909.8 1.2 352.1 115.3 55.7 0.7 53.3 0.2 19.7 10.3 20.2 68.3 51.1 194.5 342.4 1.1 473.6 1.2 308.9 2102.9 ARG2 ENSG00000081181 "Arginase 2" P78540 14 67619920-67651708 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 220.0;prostate: 108.5;thyroid gland: 105.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 190.1;Collecting duct cells: 165.5;Glandular and luminal cells: 145.2;Proximal tubular cells: 220.9;Syncytiotrophoblasts: 601.3;Urothelial cells: 165.2" "Cancer enhanced" "Detected in all" "prostate cancer: 49.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 58.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000663, CAB009435" Enhanced Supported Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB009435: AB_2059089, HPA000663: AB_1078192" "unprognostic (8.74e-3)" "unprognostic (3.06e-2)" "unprognostic (1.35e-2)" "unprognostic (2.29e-1)" "unprognostic (2.30e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-3)" "unprognostic (4.62e-3)" "unprognostic (5.37e-2)" "unprognostic (4.66e-3)" "unprognostic (1.72e-1)" "unprognostic (9.39e-2)" "unprognostic (4.26e-1)" "unprognostic (2.31e-1)" "unprognostic (4.34e-1)" "unprognostic (1.26e-1)" 2.8 7.3 5.6 2.9 6.1 0.5 4.8 6.9 13.9 17.0 7.9 2.7 3.7 7.0 3.6 16.3 1.8 9.3 3.4 6.3 11.6 64.0 3.8 3.8 0.5 6.4 7.7 18.7 5.0 220.0 45.6 8.8 9.2 108.5 1.4 22.3 17.0 5.8 35.7 2.1 15.3 3.7 5.1 0.9 3.2 3.4 6.5 3.0 105.0 52.6 1.7 17.8 9.9 5.6 8.9 1.5 14.4 9.4 2.1 0.1 20.1 6.7 17.4 20.6 34.5 36.3 4.5 14.6 1.9 4.3 9.4 2.1 58.2 26.8 24.9 0.7 14.6 6.7 2.6 41.9 6.2 1.8 37.8 1.1 33.6 10.2 49.7 1.6 35.4 37.7 19.4 0.1 1.4 4.4 2.5 1.4 27.2 4.0 0.5 0.8 2.0 16.8 16.8 14.3 31.5 12.2 4.2 4.2 6.4 32.9 15.1 1.2 7.3 6.4 15.9 0.7 5.0 1.3 2.4 4.9 12.8 7.5 10.9 0.1 0.4 0.7 0.3 0.1 0.1 0.2 0.1 0.3 0.5 0.7 0.2 0.2 0.6 0.1 0.4 0.0 0.9 1.0 5.6 6.1 6.9 13.9 6.3 11.6 6.4 7.7 9.2 5.1 6.5 5.6 3.9 0.0 5.8 5.5 8.4 8.8 190.1 17.0 7.4 5.2 41.6 28.7 6.3 4.3 20.3 165.5 10.4 86.5 14.6 9.0 37.2 8.4 16.5 75.1 18.7 5.9 36.8 8.8 20.3 3.3 6.2 5.6 37.8 145.2 7.0 23.9 2.9 1.3 14.7 10.1 41.8 24.5 12.2 0.6 3.6 3.2 0.3 9.3 10.6 7.5 0.9 40.5 1.0 9.0 9.2 5.0 5.0 0.4 5.7 95.4 72.8 220.9 3.0 17.6 6.6 6.2 8.9 8.4 3.4 9.7 5.4 601.3 15.1 2.2 8.7 165.2 ARHGAP26 "GRAF, KIAA0621, OPHN1L, OPHN1L1" ENSG00000145819 "Rho GTPase activating protein 26" Q9UNA1 5 142770377-143229011 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 237.3;Excitatory neurons: 611.6;Inhibitory neurons: 261.5;Late spermatids: 153.3;Microglial cells: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "neutrophil: 24.7;NK-cell: 9.8" "Group enriched" "Detected in many" 4 "granulocytes: 24.7;NK-cells: 9.8" "Cell line enhanced" "Detected in many" "Karpas-707: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035106, HPA035107" Enhanced Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA035106: AB_2674465, HPA035107: AB_10669855" "prognostic favorable (2.05e-4)" "prognostic favorable (1.36e-4)" "prognostic favorable (6.95e-4)" "prognostic favorable (5.93e-6)" "unprognostic (1.19e-1)" "unprognostic (1.93e-2)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.22e-1)" "unprognostic (9.43e-3)" "unprognostic (7.19e-3)" "unprognostic (8.65e-2)" "unprognostic (3.21e-3)" "unprognostic (5.67e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-2)" "prognostic favorable (2.88e-6)" 11.0 4.5 10.9 17.7 6.5 36.4 11.3 19.3 17.0 11.9 0.6 12.9 12.0 7.7 9.1 6.4 15.5 14.2 15.0 10.8 3.4 8.9 6.8 19.0 6.4 0.5 2.7 3.0 4.9 3.9 12.2 20.9 0.3 7.4 12.7 17.2 12.8 4.2 12.6 7.4 11.3 9.7 2.3 16.7 15.2 15.4 10.1 13.8 8.3 10.5 12.2 12.2 5.8 9.9 16.4 29.1 8.0 7.6 12.3 12.7 12.4 2.2 2.4 7.6 12.1 44.9 33.0 2.0 16.1 4.9 21.5 7.5 4.1 15.3 8.7 33.8 4.6 0.1 5.3 26.9 7.8 22.6 2.9 4.7 23.0 12.8 31.0 5.6 10.2 9.9 0.6 85.4 2.4 2.3 12.9 9.2 4.3 23.2 7.7 5.2 12.5 36.5 20.4 25.6 3.4 4.7 3.8 4.4 7.1 6.5 2.4 6.2 21.0 4.1 5.8 0.4 8.1 4.0 14.0 0.4 10.7 21.3 5.6 4.0 3.9 2.3 3.8 2.5 1.7 0.5 0.8 2.4 3.0 0.4 0.3 1.1 24.7 9.8 1.6 0.7 0.3 1.8 10.9 6.5 19.3 17.0 10.8 3.4 0.5 2.7 0.3 2.3 10.1 9.9 39.4 16.0 22.5 237.3 5.8 6.9 13.8 13.2 5.7 15.9 20.7 17.0 37.6 21.5 14.1 0.0 8.4 1.3 41.6 38.7 0.0 17.9 77.2 17.9 4.0 32.5 3.6 11.8 611.6 21.1 0.6 13.6 39.8 55.6 26.6 6.4 40.0 6.5 26.4 75.7 261.5 26.4 0.0 48.0 44.9 153.3 6.5 51.6 10.6 326.0 47.3 7.5 40.2 30.7 29.8 21.1 27.8 14.3 14.5 29.3 27.9 5.8 16.1 52.6 46.0 27.6 17.7 2.6 8.7 7.5 5.5 1.9 29.3 50.5 26.8 36.2 ARHGAP32 "GC-GAP, GRIT, KIAA0712, MGC1892, RICS" ENSG00000134909 "Rho GTPase activating protein 32" A7KAX9 11 128965060-129279324 "Cancer-related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 240.6;Excitatory neurons: 403.4;Inhibitory neurons: 239.7;Oligodendrocyte precursor cells: 170.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 26.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 36.6;RT4: 39.5;SK-BR-3: 42.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038382, HPA038389, HPA061505" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center" "HPA038382: AB_2675984, HPA038389: AB_10670972, HPA061505: AB_2684544" "unprognostic (1.17e-1)" "unprognostic (3.58e-2)" "unprognostic (2.54e-2)" "unprognostic (1.82e-1)" "unprognostic (3.89e-2)" "unprognostic (5.64e-2)" "unprognostic (1.52e-1)" "unprognostic (5.97e-2)" "unprognostic (7.32e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (6.64e-4)" "unprognostic (1.47e-1)" "unprognostic (6.17e-3)" "unprognostic (1.17e-1)" "unprognostic (4.01e-1)" "unprognostic (5.80e-2)" "unprognostic (1.64e-2)" 4.7 7.5 2.6 3.4 8.2 2.1 10.3 0.0 26.6 11.9 0.0 14.1 21.1 8.1 9.0 26.3 13.3 7.6 4.3 15.1 0.0 7.0 5.0 5.8 1.6 0.0 0.0 10.9 15.2 10.7 6.1 8.6 0.0 6.4 15.8 33.5 15.8 4.2 7.6 20.1 20.6 5.9 0.0 3.0 12.0 10.7 0.0 10.5 3.8 4.3 6.9 9.4 17.1 5.1 12.2 6.4 19.7 0.1 6.3 6.3 14.2 4.5 6.3 2.8 3.4 14.9 24.7 0.1 6.7 8.7 14.1 27.2 9.0 11.4 5.4 0.0 3.1 0.2 3.4 5.6 3.1 0.0 0.0 6.1 14.4 2.7 16.3 6.2 3.5 10.2 0.6 0.2 4.9 9.5 10.2 0.2 5.4 36.6 6.8 24.9 5.9 2.5 3.0 39.5 19.3 7.9 6.8 42.3 8.0 7.5 21.9 3.9 6.6 9.9 5.2 5.9 8.9 0.3 0.0 0.1 4.3 27.4 6.4 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.7 0.1 0.3 0.1 0.1 2.6 8.2 0.0 26.6 15.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 5.3 6.4 16.8 240.6 3.4 18.2 12.7 29.1 16.5 31.6 36.5 17.1 4.3 14.3 46.6 11.0 123.0 23.1 4.8 48.7 1.9 8.3 19.0 27.7 10.0 5.6 40.7 2.5 403.4 27.2 4.2 14.1 35.2 25.4 1.3 9.8 5.0 16.2 6.5 18.5 239.7 61.9 20.3 4.1 4.2 12.3 6.8 5.7 16.0 103.0 2.9 113.6 0.0 170.9 95.0 24.5 44.2 13.2 1.5 22.7 52.7 9.9 61.6 37.9 19.7 19.4 9.5 8.6 9.6 55.4 31.1 28.5 2.0 4.0 54.0 59.5 ARHGAP35 "GRF-1, GRLF1, KIAA1722, P190A, p190ARhoGAP, p190RhoGAP" ENSG00000160007 "Rho GTPase activating protein 35" Q9NRY4 19 46860997-47005077 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, GTPase activation, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 186.4;Late spermatids: 651.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037311, HPA055184, HPA056470" Approved Supported "Nuclear bodies,Aggresome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear bodies" Aggresome "CAB037311: AB_477435, HPA055184: AB_2682730, HPA056470: AB_2683142" "unprognostic (5.47e-3)" "unprognostic (1.38e-1)" "unprognostic (1.80e-1)" "unprognostic (2.40e-2)" "unprognostic (2.01e-2)" "unprognostic (7.78e-3)" "unprognostic (9.82e-3)" "unprognostic (4.41e-2)" "unprognostic (2.71e-1)" "unprognostic (2.73e-2)" "unprognostic (3.25e-2)" "unprognostic (1.92e-1)" "prognostic favorable (5.55e-8)" "unprognostic (2.78e-1)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" 13.6 10.1 35.7 8.0 31.5 5.3 16.1 16.8 31.1 12.9 9.2 14.8 12.9 12.8 10.6 15.7 12.8 9.1 25.8 37.0 27.3 19.1 22.3 14.9 8.7 26.0 32.3 17.3 13.6 31.3 14.1 7.8 34.5 13.4 12.3 16.6 15.7 15.7 29.4 11.6 16.3 12.9 19.8 8.8 10.9 40.3 33.3 10.8 20.2 24.2 9.0 13.1 9.0 25.1 52.0 56.7 37.9 34.0 33.9 27.9 6.4 27.3 38.7 27.1 31.0 30.6 18.0 27.4 19.1 112.0 41.2 30.8 34.8 35.3 36.9 19.3 14.7 37.2 40.1 24.1 31.7 22.3 30.4 28.3 35.1 30.6 32.5 37.9 24.7 18.2 25.2 9.9 31.4 30.3 21.8 35.4 19.9 37.4 20.8 24.1 26.0 8.5 23.0 100.0 37.9 36.1 50.5 47.5 20.0 23.4 44.6 27.1 31.3 23.9 18.9 26.2 33.0 10.1 19.6 21.7 53.6 22.8 59.7 0.3 0.2 0.2 0.6 0.2 0.6 0.1 0.6 0.7 0.3 0.2 0.2 0.2 0.1 0.2 0.3 0.3 0.2 0.3 35.7 31.5 16.8 31.1 37.0 27.3 26.0 32.3 34.5 19.8 33.3 25.1 15.7 44.8 38.4 47.7 8.6 15.2 13.9 20.1 19.4 31.9 35.2 23.0 58.2 27.1 21.4 25.8 25.0 3.7 14.8 61.0 7.9 14.6 186.4 17.8 19.0 19.5 31.2 16.6 42.4 20.0 1.0 19.1 19.9 34.1 9.5 30.9 27.8 89.7 15.0 69.0 48.8 18.5 14.2 19.5 7.8 651.3 23.3 11.0 21.4 32.8 14.2 28.2 18.6 37.2 58.2 20.9 21.4 25.6 6.7 23.3 44.5 22.6 10.4 22.0 19.7 22.6 24.9 45.9 23.5 24.4 16.6 1.6 16.1 29.5 25.7 17.0 ARHGEF12 "KIAA0382, LARG" ENSG00000196914 "Rho guanine nucleotide exchange factor 12" Q9NZN5 11 120336413-120489937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018911, CAB025581" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB025581: , HPA018911: AB_1845003" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (6.91e-3)" "unprognostic (1.28e-1)" "unprognostic (7.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (4.79e-2)" "unprognostic (7.77e-2)" "unprognostic (4.34e-3)" "unprognostic (4.78e-2)" "prognostic favorable (5.43e-6)" "unprognostic (1.29e-1)" "unprognostic (4.38e-2)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" 25.6 30.6 27.2 14.3 26.9 11.4 31.9 26.8 32.1 32.9 26.4 27.6 25.0 27.8 25.4 27.6 29.3 28.4 40.3 30.9 23.0 67.4 66.4 36.7 11.9 17.8 25.6 25.2 26.1 68.4 14.6 42.9 17.3 26.5 29.1 47.7 25.0 30.9 32.2 49.5 25.5 30.3 20.1 21.5 32.2 9.7 35.9 13.5 51.5 31.8 18.7 28.7 22.0 19.3 38.1 31.6 41.9 39.8 55.0 54.5 16.7 43.8 49.8 26.1 33.1 37.5 27.2 3.2 51.7 79.8 46.6 27.5 54.1 56.0 51.3 31.1 25.8 61.8 34.0 29.2 49.2 0.1 43.7 52.4 39.7 57.8 63.8 58.0 80.7 32.7 52.4 122.5 67.0 26.6 0.1 0.1 11.4 49.3 26.1 13.4 47.4 11.9 65.1 66.1 30.0 36.4 61.5 51.0 16.2 25.0 43.1 5.1 80.1 57.2 24.2 37.6 32.4 35.1 15.4 20.2 23.6 7.9 44.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 27.2 26.9 26.8 32.1 30.9 23.0 17.8 25.6 17.3 20.1 35.9 19.3 86.2 73.7 88.4 274.9 8.6 90.5 69.1 47.2 42.1 134.6 55.1 26.9 87.6 68.6 57.8 97.5 185.6 16.7 11.5 59.7 35.2 45.6 6.4 61.4 55.7 94.0 37.8 69.7 239.0 50.9 10.4 44.0 34.7 140.3 11.4 44.9 85.6 118.3 7.3 90.9 192.4 39.6 18.3 31.2 25.6 14.8 29.8 18.2 51.6 118.0 8.7 41.0 13.4 143.2 55.0 53.5 52.1 33.4 9.3 85.6 48.1 76.3 48.7 80.9 26.3 58.4 60.3 16.3 13.8 55.3 85.1 28.7 16.1 43.1 41.3 99.1 ARHGEF6 "alpha-PIX, alphaPIX, αPix, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136780932 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 193.9;Granulosa cells: 128.2;Microglial cells: 77.8" "Cancer enhanced" "Detected in all" "glioma: 24.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 117.6;HL-60: 153.7;HMC-1: 532.0;JURKAT: 152.7;U-937: 158.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003578 Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA003578: AB_1078203" "unprognostic (9.64e-2)" "unprognostic (3.47e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-2)" "unprognostic (7.28e-2)" "unprognostic (2.06e-3)" "unprognostic (9.08e-2)" "unprognostic (7.87e-3)" "unprognostic (4.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-3)" "unprognostic (5.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-3)" 44.0 16.2 23.4 30.5 24.4 31.4 23.5 25.0 19.5 10.7 11.6 13.2 7.5 12.9 5.3 7.6 7.0 17.3 32.9 25.2 26.9 6.7 8.5 25.6 41.8 26.8 29.2 16.5 3.9 10.3 6.2 46.9 27.8 7.8 11.1 4.6 8.7 8.8 68.7 6.2 14.4 16.6 29.0 39.4 12.3 3.8 26.5 51.4 5.6 54.7 39.6 14.3 8.7 30.1 1.1 0.0 5.1 0.0 11.2 28.5 0.1 1.6 9.5 1.5 8.2 0.0 0.0 5.5 2.3 8.0 7.8 0.8 6.1 0.0 1.5 28.1 2.0 117.6 0.1 0.0 4.2 153.7 532.0 30.9 0.1 5.4 0.1 10.1 3.0 152.7 0.5 22.1 20.4 0.2 70.6 88.4 4.9 0.0 2.3 26.6 37.2 0.1 1.6 29.5 0.3 6.7 0.2 1.2 4.0 2.6 3.5 61.2 0.5 7.6 1.2 9.3 7.2 3.6 0.1 57.3 35.1 158.2 10.1 57.2 16.4 71.3 13.8 18.9 16.0 6.2 15.4 11.3 19.1 5.4 13.7 12.3 9.1 12.4 16.1 6.0 21.5 15.3 23.4 24.4 25.0 19.5 25.2 26.9 26.8 29.2 27.8 29.0 26.5 30.1 18.1 6.4 8.9 57.1 22.4 1.1 0.9 0.8 1.2 0.8 16.1 10.8 60.0 0.0 2.4 1.8 0.0 0.3 23.6 0.1 1.9 0.6 12.0 0.9 2.4 13.2 0.0 11.3 20.6 1.8 0.4 10.7 5.6 1.6 193.9 128.2 12.5 2.5 15.2 13.5 21.6 0.4 0.0 46.5 25.1 35.8 14.9 40.3 3.6 77.8 36.1 4.7 36.0 48.2 4.3 0.7 0.0 14.7 12.8 0.4 0.0 0.2 2.2 0.3 13.1 33.5 18.5 0.7 0.7 0.6 1.7 0.4 40.5 30.1 0.1 0.7 ARID1A "B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1" ENSG00000117713 "AT-rich interaction domain 1A" O14497 1 26693236-26782104 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005456, CAB016334" Supported Enhanced Nucleoplasm NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB016334: AB_673396, HPA005456: AB_1078205" "unprognostic (2.83e-1)" "unprognostic (1.81e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (7.76e-2)" "unprognostic (1.01e-2)" "unprognostic (1.62e-2)" "unprognostic (6.05e-2)" "unprognostic (2.66e-1)" "unprognostic (6.54e-2)" 16.4 16.3 10.1 22.7 9.4 37.0 16.4 12.9 24.3 16.2 0.0 18.0 15.4 20.4 15.8 22.2 18.3 14.0 17.4 6.3 35.8 13.3 16.8 16.8 25.8 20.8 6.8 20.8 23.2 19.3 14.3 18.6 9.9 15.1 15.3 20.1 19.3 14.4 21.6 20.5 20.3 17.5 3.0 24.3 19.5 16.7 17.9 46.4 22.6 17.6 23.7 18.4 17.8 9.0 53.2 49.5 68.6 71.5 19.6 18.5 32.3 24.4 21.1 32.7 23.0 36.3 34.1 74.3 20.7 31.8 20.7 31.6 60.3 26.9 37.9 92.7 22.6 63.6 33.0 24.7 16.1 95.2 19.6 21.7 18.8 38.7 27.5 18.2 28.6 52.5 77.7 81.1 21.5 25.1 80.1 36.8 72.4 34.5 22.9 82.2 45.3 42.1 20.3 35.3 62.9 50.7 42.7 35.7 29.0 37.8 10.6 53.4 50.6 34.9 33.5 32.4 39.9 38.0 54.9 34.1 21.2 59.8 31.5 0.2 1.5 1.5 1.6 1.2 2.1 1.8 1.3 2.1 1.4 1.6 1.7 1.9 3.3 2.1 1.3 2.4 0.7 1.9 10.1 9.4 12.9 24.3 6.3 35.8 20.8 6.8 9.9 3.0 17.9 9.0 49.9 60.9 40.4 99.9 66.6 73.4 21.0 32.5 90.0 68.0 77.2 61.5 33.0 38.6 35.9 38.6 52.1 36.5 56.1 46.5 1.9 35.3 23.3 48.8 59.3 46.3 47.5 56.6 47.1 37.6 40.2 35.9 35.7 72.3 61.2 68.4 49.6 65.6 51.0 74.0 59.8 50.2 28.5 89.0 47.5 9.0 38.5 73.2 40.9 89.9 86.4 30.8 53.5 78.9 116.1 49.7 36.4 41.8 48.5 50.0 32.4 16.7 36.1 42.3 52.6 38.2 47.3 44.1 52.2 101.8 94.3 36.7 57.0 45.8 52.1 43.2 ARID1B "6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R" ENSG00000049618 "AT-rich interaction domain 1B" Q8NFD5 6 156776020-157210779 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 404.3;Inhibitory neurons: 475.4;Microglial cells: 327.0;Oligodendrocyte precursor cells: 417.7;Oligodendrocytes: 503.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016511, HPA075291" Approved Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA016511: AB_1845008, HPA075291: AB_2686743" "prognostic unfavorable (1.04e-4)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (5.42e-2)" "unprognostic (7.47e-2)" "unprognostic (1.40e-2)" "unprognostic (2.73e-2)" "unprognostic (2.89e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (2.53e-1)" "unprognostic (5.33e-2)" "unprognostic (1.07e-3)" "unprognostic (2.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-1)" 15.2 12.0 14.6 14.5 13.4 28.7 15.6 29.0 16.0 19.0 2.2 15.9 14.2 17.0 11.3 15.7 18.6 14.4 14.4 20.4 10.1 13.2 9.7 14.6 18.2 13.4 10.9 27.5 17.1 28.2 12.2 11.7 11.1 14.6 12.1 11.7 20.4 12.7 33.6 23.2 15.3 15.8 7.3 18.4 12.5 9.8 12.5 25.4 22.0 25.4 18.8 17.4 17.4 17.2 13.0 19.4 29.6 41.2 24.7 21.5 20.4 14.6 18.6 18.1 18.0 17.7 20.0 43.0 8.1 23.9 22.4 16.5 25.2 23.3 18.1 40.4 18.1 30.6 19.6 22.1 17.1 25.3 21.8 25.5 18.4 27.1 24.6 20.4 25.6 26.8 35.8 32.3 13.2 15.9 29.1 30.5 15.3 18.3 10.5 66.3 12.7 22.9 12.7 24.3 28.0 34.7 28.3 29.4 15.8 15.7 19.6 40.2 26.4 23.4 23.6 22.0 27.5 21.8 18.2 52.7 19.7 30.3 32.0 5.0 2.3 2.3 4.1 1.9 3.7 5.3 3.5 2.8 1.8 6.9 2.9 4.1 4.2 2.4 2.1 9.4 3.7 1.2 14.6 13.4 29.0 16.0 20.4 10.1 13.4 10.9 11.1 7.3 12.5 17.2 85.7 48.1 51.8 282.7 83.3 47.5 22.3 22.3 41.5 36.0 70.9 44.4 36.9 27.1 32.6 126.9 29.2 14.7 103.7 21.8 7.9 40.8 15.0 70.8 124.5 43.9 40.8 37.8 404.3 34.5 7.5 49.9 31.1 78.0 38.7 137.1 33.9 27.3 14.1 47.1 475.4 33.7 20.3 32.6 36.1 19.4 56.8 49.1 30.2 327.0 59.4 21.9 24.7 417.7 503.7 46.6 26.9 62.8 70.2 28.1 26.8 18.4 29.5 29.6 46.0 43.1 56.7 8.0 12.2 39.7 55.7 17.5 51.9 72.9 36.3 27.1 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729706-45908040 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 525.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA063044: AB_2684929" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favorable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 6.4 5.2 4.6 6.7 7.8 12.6 7.5 13.8 6.9 8.5 10.2 6.8 5.0 6.9 6.5 8.4 6.4 5.4 6.0 5.0 7.3 6.3 5.4 7.8 7.5 7.8 6.4 8.3 7.2 11.7 5.0 7.2 7.6 7.4 6.0 13.2 6.7 6.2 5.9 10.0 6.6 6.1 6.0 6.9 6.2 26.1 6.2 18.7 8.8 7.7 8.9 6.8 8.0 9.8 10.3 14.5 25.3 11.1 10.5 7.3 13.7 7.0 9.9 9.6 8.9 20.7 10.4 19.8 12.7 9.8 7.0 12.1 20.6 11.8 13.6 8.8 9.8 26.1 15.9 10.1 7.2 20.7 11.5 6.0 8.8 12.1 19.1 13.4 10.0 29.1 22.4 19.9 8.6 13.4 29.9 14.7 15.1 0.0 7.7 22.9 18.0 19.0 9.1 16.9 13.6 17.4 11.4 13.0 11.1 14.5 20.0 40.8 11.8 10.3 12.3 7.0 9.2 13.2 11.8 53.6 7.9 53.2 7.4 9.4 1.1 2.7 2.4 1.3 2.5 1.0 2.1 2.5 1.5 1.1 2.0 1.9 1.4 2.1 3.4 3.3 2.0 0.9 4.6 7.8 13.8 6.9 5.0 7.3 7.8 6.4 7.6 6.0 6.2 9.8 23.3 28.9 28.4 110.4 30.8 33.8 14.4 16.3 36.5 51.6 21.7 15.4 15.6 14.3 17.3 29.5 68.8 15.5 49.0 21.3 7.9 13.2 525.4 23.2 23.8 21.1 21.0 35.1 56.7 10.0 10.5 22.0 24.5 27.7 22.1 29.3 19.2 17.3 11.2 32.0 60.3 19.0 22.4 29.8 36.7 149.3 24.8 25.6 14.2 128.4 22.4 19.9 45.3 144.3 157.9 18.8 24.6 22.6 33.8 23.7 19.1 7.4 15.4 66.2 26.3 27.0 27.2 80.2 17.0 39.3 41.3 23.4 34.8 16.4 17.9 21.0 ARID5B "FLJ21150, MRF2" ENSG00000150347 "AT-rich interaction domain 5B" Q14865 10 61901684-62096944 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 968.2;Syncytiotrophoblasts: 920.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 115.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015037 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Cytosol" "HPA015037: AB_1845015" "unprognostic (3.31e-1)" "unprognostic (1.99e-2)" "unprognostic (2.94e-2)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (5.60e-2)" "unprognostic (1.50e-2)" "unprognostic (4.90e-2)" "unprognostic (3.90e-1)" "unprognostic (6.03e-2)" "unprognostic (1.97e-1)" "unprognostic (5.75e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (2.58e-1)" "unprognostic (1.94e-1)" "unprognostic (3.93e-2)" 50.0 8.1 2.9 21.2 5.8 6.9 34.3 3.2 11.3 37.2 20.7 17.5 10.2 39.0 4.6 20.2 20.6 39.3 18.3 4.4 1.6 21.4 8.3 18.3 18.8 7.8 6.9 17.5 6.2 13.3 10.0 21.0 11.4 18.3 11.7 4.1 15.8 10.2 87.2 18.1 14.2 42.5 0.9 16.9 11.5 6.9 9.0 13.1 7.8 11.9 16.7 30.9 19.6 9.7 2.2 0.9 6.0 14.7 13.0 34.0 1.2 42.9 115.2 29.9 23.3 52.7 2.3 3.9 10.1 41.4 4.3 14.3 20.6 6.5 36.0 13.7 6.1 2.1 10.4 13.5 23.9 0.6 25.2 43.3 3.4 17.6 20.2 26.2 3.9 7.5 1.9 5.7 9.9 7.7 14.4 1.1 1.1 10.2 13.5 17.7 9.8 1.1 20.1 23.9 3.3 4.4 19.2 10.6 12.8 13.1 8.7 0.7 3.3 16.5 22.0 25.1 10.9 0.4 0.0 11.4 14.3 0.8 5.4 9.6 1.2 0.8 13.3 2.8 1.8 37.5 19.7 11.8 2.2 41.2 12.8 8.4 2.2 12.3 8.2 1.0 30.9 5.4 2.9 5.8 3.2 11.3 4.4 1.6 7.8 6.9 11.4 0.9 9.0 9.7 86.2 131.4 70.7 54.5 199.8 968.2 453.9 111.3 105.9 54.4 112.8 96.6 72.8 27.1 96.3 51.5 0.0 187.8 89.1 7.5 99.7 56.1 31.7 164.7 231.0 134.1 36.4 5.2 167.8 14.6 150.7 343.6 21.4 457.7 24.6 37.6 119.2 7.4 51.0 74.0 181.9 18.7 22.4 44.1 162.4 20.1 151.6 43.6 138.7 34.7 39.0 17.2 58.7 74.4 155.8 41.1 25.2 60.5 234.5 193.7 5.4 304.8 38.4 3.6 131.5 496.3 463.9 8.2 5.8 65.7 477.8 920.4 178.2 24.3 41.7 233.9 ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "U-698: 397.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Nuclear bodies" "CAB004318: AB_626698, HPA001759: AB_1078213" "unprognostic (1.81e-1)" "unprognostic (8.14e-2)" "unprognostic (6.87e-2)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (9.43e-2)" "unprognostic (5.27e-3)" "unprognostic (5.05e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (9.52e-2)" "unprognostic (1.85e-3)" "unprognostic (2.68e-1)" "unprognostic (4.67e-1)" "unprognostic (6.45e-2)" "unprognostic (6.92e-2)" 25.8 20.4 9.6 18.1 9.6 17.1 22.7 16.2 12.2 31.8 16.5 19.5 15.0 27.4 14.8 19.2 25.0 20.5 20.7 8.9 10.7 17.8 42.9 24.7 17.5 10.4 9.5 37.7 28.6 19.6 12.5 31.2 10.2 16.3 21.2 39.1 15.5 17.6 32.3 23.9 17.0 29.0 8.0 19.5 19.0 17.3 10.9 20.4 19.6 28.1 22.4 21.3 24.0 11.2 17.1 17.2 25.6 19.5 53.4 50.9 34.2 19.0 36.9 25.2 22.7 15.1 17.0 18.3 16.5 34.0 12.4 19.1 24.2 21.3 21.9 29.3 13.8 21.4 28.7 17.6 31.0 26.4 24.7 39.9 20.0 30.7 26.9 30.6 31.3 24.4 27.9 34.9 26.3 33.8 21.1 15.0 21.2 30.9 13.0 26.1 30.8 25.5 20.6 17.4 17.6 25.1 36.6 25.3 15.2 34.4 32.6 59.4 22.6 20.9 18.8 16.8 16.8 39.8 30.8 397.5 25.5 0.9 14.4 46.6 23.6 21.2 12.1 21.6 11.1 8.7 10.0 11.7 18.7 8.7 9.5 9.8 11.9 12.0 23.4 7.8 11.1 16.2 9.6 9.6 16.2 12.2 8.9 10.7 10.4 9.5 10.2 8.0 10.9 11.2 14.8 12.8 10.3 28.1 14.9 14.1 9.9 11.0 8.0 23.6 10.2 6.9 12.8 24.3 11.6 11.0 54.2 24.5 12.6 13.3 3.9 11.2 5.0 10.3 23.3 14.8 20.4 16.6 41.6 9.7 37.1 25.4 8.6 20.6 3.8 17.1 30.0 47.7 20.3 6.7 47.5 16.5 8.2 39.1 20.1 4.3 32.3 20.0 10.6 39.4 27.9 7.9 13.4 41.7 50.9 9.6 8.1 32.7 13.0 8.8 10.1 13.1 9.7 38.3 13.1 17.0 19.4 18.4 16.7 11.0 15.3 29.6 12.7 20.7 9.0 10.0 ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 386.9" "Cell type enhanced" "Detected in all" "Muller glia cells: 468.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 890.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA055161: AB_2682721, HPA059303: AB_2683973" "unprognostic (8.07e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (2.74e-2)" 386.9 160.3 64.7 50.6 69.2 16.9 106.9 102.3 88.9 65.6 84.4 78.8 45.6 49.3 44.7 71.4 46.9 61.0 111.3 64.5 58.4 59.5 74.9 74.1 20.3 54.0 69.2 62.2 44.7 38.7 36.3 47.9 52.2 48.3 84.9 219.5 101.9 70.2 357.6 35.2 45.5 67.5 44.8 28.6 105.0 16.5 71.8 16.7 97.0 182.7 28.5 112.2 43.8 60.4 460.3 652.3 89.9 55.1 392.1 370.1 31.2 804.0 741.3 336.3 350.1 113.1 594.2 35.3 54.3 474.6 270.3 167.5 56.2 281.1 570.0 13.6 57.0 81.1 372.5 310.3 251.2 12.5 12.9 306.5 61.9 187.6 237.4 657.2 144.8 18.0 22.2 32.1 300.2 97.4 3.3 16.6 51.7 441.6 383.4 22.3 97.0 7.3 206.2 374.0 93.1 32.1 249.9 116.1 101.7 49.0 47.7 22.2 456.7 338.0 174.3 313.0 288.0 20.2 27.1 1.5 890.1 7.5 231.4 1.9 8.3 0.3 2.5 2.9 4.7 5.5 3.5 2.4 10.0 5.0 4.9 2.5 25.4 8.7 1.8 34.0 4.0 4.1 64.7 69.2 102.3 88.9 64.5 58.4 54.0 69.2 52.2 44.8 71.8 60.4 79.1 195.5 244.0 366.6 13.8 47.0 160.7 126.0 68.9 138.3 83.7 58.4 228.6 37.1 157.5 86.5 294.0 118.1 40.3 57.0 15.6 144.2 1.6 51.4 65.8 85.9 116.5 13.0 93.1 180.4 107.1 132.0 73.9 115.4 8.2 34.5 42.8 62.6 72.2 127.9 98.9 215.1 52.9 26.6 44.1 3.1 70.8 48.1 42.7 61.8 20.0 468.8 2.1 154.8 53.5 257.7 32.3 57.6 15.9 148.2 34.3 34.6 66.6 158.8 46.0 114.4 92.7 3.4 16.8 101.7 50.3 48.0 13.6 131.2 67.3 254.2 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 298.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 16.5 20.4 16.6 8.4 17.0 15.0 16.9 16.5 20.4 16.2 17.7 16.0 13.6 15.6 7.9 16.8 14.0 7.7 26.1 16.2 15.5 27.3 57.9 17.3 12.2 20.1 16.6 13.4 22.8 14.8 30.6 12.9 18.3 21.6 4.6 5.7 18.3 6.7 44.3 20.5 18.1 5.2 14.7 20.7 22.7 30.0 17.2 8.3 25.9 5.8 6.4 16.0 14.2 21.5 19.3 33.3 13.0 17.9 7.5 9.3 55.4 17.7 12.6 19.3 19.5 20.3 21.3 19.2 18.1 12.4 16.3 9.8 12.0 13.1 6.2 12.9 41.0 21.4 28.7 298.1 25.5 19.1 29.9 10.9 13.9 9.5 6.6 10.0 19.5 16.0 22.0 25.0 11.6 65.0 16.9 41.8 15.5 32.8 23.5 19.2 18.7 39.4 18.0 17.0 32.4 34.8 14.6 42.2 35.2 12.3 27.2 41.4 16.6 35.7 24.5 26.4 22.8 20.2 12.5 21.6 19.2 19.3 21.3 24.0 11.7 8.6 6.6 8.0 3.7 9.0 10.0 8.8 14.7 9.0 7.7 5.8 2.7 8.0 10.4 9.3 5.3 5.6 16.6 17.0 16.5 20.4 16.2 15.5 20.1 16.6 18.3 14.7 17.2 21.5 13.9 9.6 44.7 19.9 24.1 13.4 23.7 24.4 23.3 23.3 19.6 15.6 13.6 27.1 19.8 14.7 41.7 73.7 25.8 29.3 39.2 24.2 49.1 16.2 14.9 16.1 25.0 17.9 12.4 26.2 222.6 17.5 46.9 20.1 21.5 31.0 12.8 56.1 44.7 50.5 12.1 31.5 20.3 26.7 18.6 96.0 11.8 21.7 19.6 1.9 23.8 57.8 19.6 10.6 14.1 17.6 25.8 17.7 27.3 24.9 42.5 58.3 18.5 39.4 13.1 14.7 37.4 41.7 51.0 20.3 14.3 59.4 18.4 23.6 33.3 23.1 ASXL1 KIAA0978 ENSG00000171456 "ASXL transcriptional regulator 1" Q8IXJ9 20 32358330-32439319 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor" "Cancer-related genes, Craniosynostosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064156 Approved Nucleoplasm,Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "HPA064156: AB_2685200" "unprognostic (1.49e-1)" "unprognostic (5.97e-2)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.86e-4)" "unprognostic (6.69e-2)" "prognostic favorable (9.16e-4)" "unprognostic (2.01e-3)" "unprognostic (2.89e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-1)" "unprognostic (4.32e-2)" "unprognostic (3.21e-2)" "unprognostic (1.84e-3)" "unprognostic (5.47e-2)" "unprognostic (1.90e-1)" "unprognostic (4.82e-2)" "unprognostic (1.06e-1)" 31.6 24.6 13.4 18.1 14.4 36.9 30.5 15.0 14.4 30.6 20.2 31.6 12.2 26.8 15.6 17.2 28.6 13.7 21.8 14.1 15.6 28.7 32.8 36.0 24.0 15.8 14.2 32.3 32.9 13.1 19.2 17.3 13.8 24.8 13.2 19.7 21.0 13.3 30.1 23.2 27.8 18.4 13.8 35.0 24.7 37.2 15.1 27.4 32.0 16.4 25.0 26.4 24.2 17.1 59.2 33.6 52.7 28.2 23.6 28.6 45.6 35.4 33.0 64.1 48.6 99.8 35.2 54.4 24.5 47.3 62.2 39.5 45.3 37.8 53.2 70.6 24.1 88.9 53.6 55.7 21.6 38.5 36.1 32.4 25.1 46.1 35.6 33.3 37.4 45.3 45.2 29.1 31.9 18.4 51.7 30.3 12.9 27.7 38.9 30.8 62.1 24.8 27.1 28.4 23.7 38.2 68.9 23.5 31.7 27.9 32.7 27.0 39.9 69.1 59.4 32.3 43.2 33.9 38.6 39.3 34.0 100.2 27.8 0.1 0.6 1.0 2.6 0.5 2.5 4.8 3.6 3.9 0.8 3.3 3.5 4.0 0.5 1.5 0.6 2.7 9.0 1.5 13.4 14.4 15.0 14.4 14.1 15.6 15.8 14.2 13.8 13.8 15.1 17.1 92.3 51.3 35.5 54.9 63.3 40.0 51.8 8.6 50.7 21.4 52.9 48.6 19.8 15.7 17.9 27.6 52.1 18.0 55.2 18.8 25.4 13.5 97.8 59.4 80.1 65.6 7.2 40.8 61.4 12.6 16.5 49.8 30.5 86.2 18.3 57.7 41.0 34.7 21.3 18.5 80.3 14.1 16.2 21.2 42.2 84.9 25.4 33.5 78.2 75.9 16.7 11.6 20.6 78.4 125.9 15.6 13.7 14.7 94.6 49.6 29.9 31.7 20.8 30.7 6.6 96.7 62.7 31.0 16.1 34.6 30.5 5.9 67.2 36.4 17.5 40.5 ASXL2 "ASXH2, FLJ10898, KIAA1685" ENSG00000143970 "ASXL transcriptional regulator 2" Q76L83 2 25733753-25878487 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034646, HPA058040" Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA034646: AB_2674261, HPA058040: AB_2683586" "unprognostic (4.78e-2)" "unprognostic (3.41e-2)" "unprognostic (2.23e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.88e-2)" "unprognostic (2.98e-2)" "unprognostic (2.80e-1)" "unprognostic (2.68e-3)" "unprognostic (3.17e-2)" "unprognostic (1.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.33e-3)" "unprognostic (1.82e-1)" "unprognostic (1.58e-1)" "unprognostic (2.31e-1)" "unprognostic (3.75e-2)" 6.8 6.2 3.8 9.5 5.1 8.3 7.2 4.8 3.9 8.2 4.5 9.1 6.4 7.1 5.0 7.7 7.2 6.8 7.1 3.5 7.7 8.7 6.1 6.9 11.1 7.5 5.0 6.6 7.7 14.1 3.5 7.1 7.5 6.3 8.9 8.8 6.6 6.3 8.0 7.6 7.1 8.2 3.6 9.9 7.8 17.7 6.3 13.9 10.5 7.3 10.5 7.5 4.2 6.4 25.1 23.1 11.0 7.8 9.8 13.7 12.9 16.0 19.0 12.4 10.5 19.4 12.6 14.8 9.7 13.9 13.8 14.1 21.1 14.9 16.9 22.5 10.2 32.9 20.1 16.6 8.3 42.2 25.1 6.8 15.2 17.9 15.3 10.4 15.2 8.8 29.0 12.2 12.5 9.2 15.5 9.2 14.4 13.2 9.4 15.4 48.2 11.4 10.7 30.1 11.3 12.5 22.2 13.9 13.5 10.4 8.9 12.3 31.4 16.6 22.0 15.9 22.4 26.8 39.8 41.0 15.5 27.4 13.2 1.7 2.7 4.2 2.7 1.4 2.3 2.2 1.9 1.9 1.5 2.0 2.2 2.5 6.0 1.2 3.3 2.3 2.2 0.8 3.8 5.1 4.8 3.9 3.5 7.7 7.5 5.0 7.5 3.6 6.3 6.4 16.1 25.6 24.1 54.2 25.9 32.4 8.9 15.9 29.0 22.3 19.1 10.8 27.0 14.3 19.1 9.2 25.0 10.2 22.5 20.1 15.6 15.7 48.9 25.8 20.4 22.0 10.3 33.6 62.5 14.4 9.4 17.3 24.5 19.8 23.5 12.6 28.5 12.6 18.2 25.2 47.6 16.8 18.3 25.7 23.6 26.9 19.6 25.2 23.2 68.4 34.4 12.4 12.3 46.3 72.8 18.4 14.2 13.2 29.8 13.4 12.4 14.3 41.3 24.9 39.5 20.6 16.8 34.4 26.6 29.7 41.1 14.6 45.0 17.2 19.7 19.3 ATF1 TREB36 ENSG00000123268 "Activating transcription factor 1" P18846 12 50763710-50821162 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016222, HPA055069, HPA055406" Supported Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB016222: AB_2290030, HPA055069: AB_2682688, HPA055406: AB_2682807" "unprognostic (1.71e-1)" "unprognostic (1.50e-3)" "unprognostic (1.50e-1)" "unprognostic (9.05e-2)" "unprognostic (6.68e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.53e-5)" "unprognostic (3.65e-1)" "unprognostic (8.17e-3)" "unprognostic (5.94e-2)" "unprognostic (4.31e-3)" "unprognostic (5.52e-2)" "unprognostic (1.73e-1)" "unprognostic (2.74e-2)" "unprognostic (2.46e-1)" "unprognostic (2.27e-1)" "unprognostic (8.75e-2)" 13.8 21.2 4.9 15.8 5.1 14.8 16.8 14.2 7.1 16.7 8.2 18.0 16.0 18.2 13.7 17.0 17.8 16.5 14.6 4.8 7.9 17.4 20.8 15.8 21.5 5.3 5.8 23.1 9.1 19.8 10.1 16.7 5.4 14.3 18.6 11.9 14.5 13.5 32.4 10.4 14.7 16.7 5.4 17.9 14.3 8.6 6.6 29.2 22.7 23.7 21.5 16.5 12.9 6.9 28.6 20.4 21.0 21.4 29.0 30.4 52.2 29.5 50.7 45.7 35.8 41.7 43.7 38.7 47.6 34.5 20.0 22.8 24.9 30.6 47.6 39.0 25.8 42.8 43.1 22.6 56.5 62.3 39.6 33.7 45.7 32.8 52.8 47.6 22.5 27.1 53.2 36.2 33.9 42.4 39.6 37.3 30.0 33.0 32.1 37.5 32.3 45.9 33.6 19.5 27.9 14.9 61.8 26.5 44.7 28.5 37.3 37.6 16.1 32.1 38.2 26.4 24.1 20.2 25.8 63.6 30.9 33.9 15.3 6.6 17.9 42.7 20.2 18.8 23.1 20.2 21.7 24.1 21.1 21.7 26.4 20.4 11.2 20.8 12.7 9.6 28.8 19.1 4.9 5.1 14.2 7.1 4.8 7.9 5.3 5.8 5.4 5.4 6.6 6.9 25.5 54.5 18.5 22.2 41.5 75.3 48.4 34.8 52.3 12.1 26.0 18.5 14.6 15.7 26.7 12.9 0.0 34.6 25.4 23.4 52.8 24.9 9.2 24.6 20.8 23.8 6.0 46.7 25.8 21.1 77.1 33.1 14.3 21.0 10.1 14.1 20.0 16.2 27.5 13.5 29.2 18.7 24.4 25.2 48.4 5.9 32.0 24.2 23.2 16.9 24.6 14.2 27.8 12.5 25.3 22.8 17.9 27.8 22.1 43.7 20.7 34.6 19.9 7.2 39.5 34.1 33.7 10.9 10.3 30.3 54.6 80.6 38.4 20.4 22.8 36.9 ATG13 KIAA0652 ENSG00000175224 "Autophagy related 13" O75143 11 46617527-46674818 "Cancer-related genes, Predicted intracellular proteins, Transporters" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039350 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA039350: AB_10673142" "unprognostic (3.66e-1)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-1)" "unprognostic (5.36e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.59e-5)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (7.57e-2)" "unprognostic (2.44e-2)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" "unprognostic (7.68e-2)" "unprognostic (3.47e-1)" 32.3 39.7 55.9 26.1 67.6 60.5 30.1 49.4 63.7 30.6 46.1 26.5 29.3 28.2 32.2 32.0 32.1 29.6 36.8 55.2 51.8 28.7 43.9 25.3 31.5 60.2 59.4 29.7 44.6 37.5 57.7 21.9 61.8 31.1 24.1 48.4 35.9 25.5 34.5 39.6 28.0 24.8 51.8 36.4 36.4 82.0 59.6 40.6 36.8 33.4 33.6 27.4 29.1 87.9 32.8 58.5 44.1 26.1 60.2 70.0 44.5 37.5 65.4 45.0 57.0 40.2 31.7 30.2 25.6 56.5 58.1 38.8 42.7 50.3 45.2 57.9 81.1 32.8 39.7 71.2 67.4 44.1 54.1 84.9 59.0 31.0 67.9 63.9 45.0 69.4 57.8 66.8 40.8 48.8 44.0 65.1 55.0 59.5 49.9 41.4 57.0 53.7 29.9 34.5 41.6 42.1 51.2 40.6 55.4 42.1 58.0 89.5 44.6 54.7 33.3 51.1 41.2 61.1 73.8 38.6 67.8 39.3 40.9 41.7 36.1 48.5 35.1 42.6 27.9 27.1 31.2 27.8 35.0 21.7 26.4 29.2 67.7 31.5 35.1 25.6 44.7 39.9 55.9 67.6 49.4 63.7 55.2 51.8 60.2 59.4 61.8 51.8 59.6 87.9 10.6 16.0 16.2 14.7 16.9 9.3 12.0 9.0 13.1 22.7 16.7 12.3 13.2 8.6 12.0 12.9 39.6 9.9 25.4 24.5 7.9 18.9 42.7 30.0 17.3 12.7 18.0 28.2 23.4 32.3 22.4 14.8 20.9 46.1 8.8 22.5 13.2 22.5 15.1 33.7 25.7 22.6 14.2 19.1 9.8 46.8 11.5 15.7 12.4 15.0 22.8 16.3 19.6 25.1 61.0 30.4 12.9 11.3 36.6 19.9 19.5 13.5 9.4 32.2 13.1 16.9 19.9 46.3 16.3 15.8 11.5 26.4 18.0 9.8 11.9 24.3 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 171.4;Extravillous trophoblasts: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 3900000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Plasma membrane" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 24.8 26.0 19.8 31.7 23.4 26.4 33.9 21.4 23.5 22.2 18.8 36.4 32.0 30.0 20.3 19.4 29.4 20.4 21.3 19.6 21.5 32.7 34.6 18.0 44.9 20.5 21.5 32.0 26.2 29.6 18.6 37.3 23.3 28.7 47.5 19.1 18.8 38.4 43.2 23.8 27.2 37.0 21.0 27.6 24.5 20.1 22.9 41.8 22.5 25.4 51.8 29.1 17.6 27.5 102.2 133.8 85.1 144.0 112.5 113.2 40.6 105.4 91.9 117.4 134.9 278.6 157.3 149.6 122.8 110.0 164.5 106.7 187.8 157.0 169.5 113.4 189.3 179.1 108.7 271.5 145.4 226.1 92.0 98.4 119.8 154.7 188.5 82.0 79.7 144.5 237.0 124.4 166.3 178.7 203.4 112.1 330.3 167.4 84.9 185.8 117.3 133.4 126.4 146.5 129.3 87.8 84.3 103.1 124.3 189.2 169.7 82.9 70.2 96.0 101.2 127.3 65.8 160.3 195.7 300.1 85.6 124.5 146.8 12.6 16.4 0.4 34.6 23.5 59.1 56.6 49.0 53.8 36.3 39.9 50.0 46.9 1.8 55.4 21.1 31.7 50.2 29.0 19.8 23.4 21.4 23.5 19.6 21.5 20.5 21.5 23.3 21.0 22.9 27.5 7.2 12.8 19.3 18.6 34.7 15.0 28.2 55.0 30.7 10.0 18.2 16.1 21.1 28.6 33.3 23.9 4.2 171.4 23.3 17.6 27.4 45.2 1.1 20.7 28.2 6.1 19.2 32.2 15.4 49.3 166.3 25.3 22.4 20.8 25.3 32.9 5.3 22.2 52.4 10.1 15.4 33.8 26.4 14.4 10.8 1.7 23.9 20.2 30.2 2.8 26.1 21.3 26.8 16.6 25.7 32.4 28.5 34.3 36.3 24.0 18.8 52.7 27.3 14.7 26.3 19.2 29.0 3.3 43.8 24.6 8.5 95.4 29.8 40.7 58.4 18.1 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222832-108369102 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 210.6;NK-cells: 339.8;Oligodendrocytes: 217.6;Rod photoreceptor cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 78.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 6.2 7.4 8.2 17.5 15.0 16.2 8.5 17.0 12.3 8.7 16.1 6.7 5.2 10.0 9.9 4.0 7.5 8.2 7.0 7.3 11.3 5.8 7.8 7.6 33.7 15.8 13.1 15.8 14.8 9.3 12.1 8.0 17.0 6.3 7.0 20.6 11.4 6.1 4.4 7.5 12.6 6.9 10.3 22.2 8.6 5.2 12.7 18.2 8.8 6.0 25.9 7.1 6.9 28.8 4.3 6.8 14.8 7.6 20.2 29.1 3.1 10.9 13.5 6.4 11.3 7.1 10.3 18.3 14.0 10.2 9.6 7.7 11.6 10.8 9.0 12.3 5.7 15.2 8.7 10.2 10.5 16.4 17.0 18.3 6.3 10.0 21.2 15.2 14.1 16.5 12.4 9.9 14.3 3.4 10.6 18.5 9.8 8.6 7.4 9.7 9.7 24.9 8.1 7.5 9.0 10.5 11.1 4.7 20.6 13.2 9.3 10.1 23.7 15.8 8.4 7.3 9.0 6.2 7.0 78.3 7.0 19.0 18.8 21.3 5.5 4.0 16.5 5.7 11.1 11.6 11.7 12.5 2.6 13.0 21.1 20.4 9.9 9.7 13.3 6.2 6.1 5.3 8.2 15.0 17.0 12.3 7.3 11.3 15.8 13.1 17.0 10.3 12.7 28.8 23.7 38.5 20.8 62.7 146.4 12.6 17.5 21.1 28.5 111.0 19.6 14.2 39.9 12.8 19.5 22.0 210.6 16.9 140.2 4.2 5.9 9.9 19.2 14.4 52.1 25.9 20.4 39.1 70.2 12.3 13.2 39.0 12.8 20.9 13.3 45.9 32.9 23.3 29.1 60.6 82.8 14.9 26.4 96.4 34.0 5.1 39.4 69.2 26.6 178.9 63.2 27.3 339.8 85.5 217.6 7.6 7.6 27.8 96.5 9.1 8.9 11.1 16.0 200.1 26.3 41.4 29.2 31.5 37.4 15.8 12.4 4.2 147.7 52.3 11.5 10.2 ATOH1 "bHLHa14, HATH1, MATH-1, Math1" ENSG00000172238 "Atonal bHLH transcription factor 1" Q92858 4 93828753-93830964 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 20.0" "Cell type enriched" "Detected in some" 30 "Intestinal goblet cells: 226.1" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049400 Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Intestine - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Mitochondria "Nucleoplasm, Cytosol" "HPA049400: " "prognostic favorable (3.26e-5)" "unprognostic (5.20e-1)" "unprognostic (2.69e-1)" "unprognostic (1.26e-1)" "unprognostic (2.70e-1)" 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.1 20.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 226.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Mental retardation, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1482.3" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1879.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 2979.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced NA NA 420000 "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favorable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.01e-4)" 150.9 206.6 115.5 144.1 135.7 104.3 220.2 176.4 264.7 137.6 209.2 580.5 785.5 92.3 304.6 255.9 143.6 361.3 233.1 176.0 133.9 1127.5 132.5 255.7 89.7 140.8 103.5 137.7 661.3 1482.3 160.6 120.0 196.3 176.4 542.6 301.2 721.9 294.1 147.3 316.6 813.9 146.1 117.4 78.1 201.5 140.0 104.1 92.8 744.4 117.7 132.4 149.7 187.4 142.2 399.8 144.8 147.2 74.5 288.8 277.5 750.8 232.9 462.9 281.6 396.6 583.9 278.5 314.2 321.3 279.0 284.4 505.1 293.8 493.7 406.2 116.1 324.2 183.5 249.2 498.4 220.1 465.2 246.1 311.6 808.0 328.4 429.0 395.5 350.8 187.4 306.9 294.2 253.0 793.7 189.6 167.7 346.0 630.5 285.6 179.7 343.4 278.6 1023.2 405.1 143.8 126.7 363.0 679.6 2979.2 358.2 179.1 265.9 311.9 159.4 221.4 415.4 479.5 140.7 118.1 238.0 488.2 263.1 956.1 19.2 36.6 17.2 59.7 56.6 62.8 26.4 66.9 64.2 59.6 15.2 76.5 55.5 4.5 30.8 86.0 30.4 57.6 53.6 115.5 135.7 176.4 264.7 176.0 133.9 140.8 103.5 196.3 117.4 104.1 142.2 199.2 275.7 295.3 26.8 84.6 276.8 336.8 220.5 390.9 101.0 189.2 145.2 74.1 579.0 238.4 770.6 398.2 83.7 89.1 789.9 373.7 625.6 31.2 205.4 54.3 201.6 176.4 89.2 130.5 315.6 160.6 141.6 134.6 372.1 43.8 212.6 144.2 71.2 129.8 102.6 123.9 353.4 463.9 98.8 254.2 19.3 117.8 145.5 208.1 36.5 56.9 556.8 64.9 77.9 60.9 187.6 307.8 100.8 73.2 271.6 1879.9 308.2 171.6 147.7 32.9 109.8 147.4 20.2 35.8 320.7 268.9 67.6 133.3 58.3 498.6 280.6 ATP2B3 "CFAP39, CLA2, PMCA3, SCAX1" ENSG00000067842 "ATPase plasma membrane Ca2+ transporting 3" Q16720 X 153517676-153582939 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 187.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.1;Endometrial ciliated cells: 6.5;Excitatory neurons: 23.7;Extravillous trophoblasts: 10.7;Inhibitory neurons: 30.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.9;SH-SY5Y: 2.9;THP-1: 2.5;U-937: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001583 Enhanced Supported NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 10: Non-specific - Unknown function" "HPA001583: AB_1079641" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (3.28e-1)" "unprognostic (6.82e-2)" "unprognostic (1.30e-1)" "unprognostic (4.32e-2)" "unprognostic (2.67e-1)" "unprognostic (6.34e-2)" "unprognostic (2.68e-2)" "unprognostic (8.58e-2)" "unprognostic (1.38e-3)" "unprognostic (3.44e-1)" "unprognostic (2.71e-12)" "unprognostic (1.44e-3)" "unprognostic (2.04e-1)" "unprognostic (2.42e-2)" 0.0 9.7 6.0 0.0 7.5 0.0 0.0 3.4 33.7 0.0 187.9 0.3 0.0 0.0 0.9 0.0 1.2 0.0 0.0 25.7 1.3 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 1.4 0.5 4.8 0.0 0.0 2.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 2.9 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 7.5 3.4 33.7 25.7 1.3 5.5 0.0 4.8 0.0 2.7 12.2 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 1.3 0.1 0.0 0.0 23.7 0.0 10.7 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 30.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.4 0.0 3.5 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.6 4.5 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.9;Early spermatids: 30.2;Excitatory neurons: 24.5;Hepatocytes: 23.6;Inhibitory neurons: 25.4;Late spermatids: 74.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 32.8;CACO-2: 21.1;HEL: 53.0;RPTEC TERT1: 22.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA009137: AB_2668214, HPA013187: AB_1845206" "unprognostic (1.13e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (3.49e-1)" "unprognostic (5.51e-2)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (8.29e-2)" "unprognostic (1.17e-1)" "unprognostic (3.26e-3)" "unprognostic (4.66e-2)" "unprognostic (3.54e-1)" "unprognostic (6.21e-3)" "unprognostic (1.40e-1)" 3.6 0.9 1.3 0.6 1.2 2.2 1.7 2.0 2.1 1.8 0.8 2.9 10.6 1.5 0.1 0.7 2.0 7.0 2.1 2.5 1.4 2.2 8.6 1.4 0.3 0.8 1.2 1.9 2.0 6.4 1.2 7.1 1.1 2.0 2.7 3.7 3.0 0.9 1.1 1.0 6.0 1.7 0.5 0.4 4.4 8.4 1.7 0.7 1.2 1.8 0.2 1.6 1.2 0.7 0.8 2.8 5.2 4.5 1.0 0.8 32.8 1.5 0.5 1.6 1.2 21.1 0.1 0.1 0.6 2.7 3.6 0.3 4.0 4.4 1.0 0.4 7.5 53.0 0.5 14.7 1.4 0.6 11.8 1.9 4.7 0.2 2.0 2.1 3.7 3.7 14.4 0.2 1.5 1.0 0.2 0.9 1.7 6.6 1.8 2.0 1.4 0.0 22.5 3.4 3.3 2.2 1.9 2.8 1.8 5.5 8.0 0.5 2.0 0.3 1.7 2.8 0.6 0.6 0.7 0.2 0.1 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 2.0 2.1 2.5 1.4 0.8 1.2 1.1 0.5 1.7 0.7 5.4 6.4 0.0 10.7 0.9 0.4 0.7 1.7 0.0 3.1 2.3 1.8 2.1 4.3 5.2 1.8 22.9 14.3 1.8 6.6 0.0 1.6 30.2 2.4 1.3 2.7 2.4 4.2 24.5 1.0 5.5 2.1 9.2 4.2 0.0 13.3 3.9 23.6 2.3 0.0 25.4 3.4 4.1 0.8 0.3 74.2 2.1 0.2 1.8 15.0 0.2 0.2 0.0 12.1 4.3 2.0 3.0 0.7 0.2 1.3 11.4 2.2 4.3 6.1 6.6 1.0 1.4 2.2 1.7 0.7 0.4 4.5 0.2 0.4 5.0 1.2 ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449007-142578733 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.0;Inhibitory neurons: 94.4;Microglial cells: 73.1;Oligodendrocyte precursor cells: 65.4;Oligodendrocytes: 71.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Golgi apparatus" "HPA054320: AB_2682448" "unprognostic (1.47e-1)" "unprognostic (8.90e-2)" "unprognostic (2.90e-1)" "unprognostic (4.23e-2)" "unprognostic (2.25e-2)" "unprognostic (6.42e-2)" "prognostic unfavorable (8.39e-5)" "unprognostic (3.44e-1)" "unprognostic (1.67e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.94e-1)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.55e-1)" "unprognostic (1.69e-2)" "unprognostic (1.43e-1)" 3.0 8.6 0.7 4.1 1.1 1.2 3.2 0.9 1.4 3.8 3.7 2.7 1.7 3.3 2.3 3.1 3.3 3.4 2.3 1.2 1.9 3.7 3.6 2.9 4.8 1.5 1.2 2.7 3.8 5.2 3.7 3.1 1.4 3.0 2.9 2.9 3.5 2.5 2.9 2.7 3.1 3.2 1.0 4.2 2.8 5.2 1.2 4.9 5.0 1.4 4.6 4.1 2.7 1.2 28.6 13.2 7.1 7.0 9.6 13.6 8.8 14.8 8.4 10.1 9.7 6.4 6.8 19.9 14.6 10.1 14.6 16.1 10.9 12.8 15.0 7.5 7.9 11.9 8.2 4.1 4.2 20.5 5.3 9.8 4.8 9.5 10.3 5.8 11.6 8.7 8.2 7.5 9.6 7.5 13.9 2.6 7.3 15.6 9.6 11.8 12.5 13.5 6.3 11.1 5.2 5.1 28.6 8.3 8.0 7.8 12.0 5.4 14.6 10.5 4.9 12.3 15.2 10.8 7.4 18.5 13.8 6.5 8.5 0.0 0.3 0.0 0.5 0.4 1.0 0.1 0.3 0.5 0.7 0.3 0.4 0.4 0.0 1.3 0.2 0.2 0.4 0.2 0.7 1.1 0.9 1.4 1.2 1.9 1.5 1.2 1.4 1.0 1.2 1.2 11.5 6.4 10.6 39.2 22.4 4.0 7.2 8.8 14.2 14.1 9.2 6.5 7.6 5.7 10.1 3.7 37.5 7.7 14.9 3.5 0.0 5.9 16.4 18.8 18.6 10.2 7.7 14.5 93.0 4.9 3.6 8.3 14.8 10.3 1.3 16.3 7.9 7.3 6.4 8.4 94.4 4.8 14.2 9.4 4.0 8.7 6.5 12.8 10.6 73.1 12.0 6.0 9.2 65.4 71.9 6.4 1.8 7.2 23.1 8.1 1.9 6.5 25.4 23.6 0.0 14.6 9.8 50.1 18.5 14.7 4.5 5.1 15.1 13.8 7.6 6.1 ATRX "JMS, MRX52, RAD54, XH2, XNP" ENSG00000085224 "ATRX chromatin remodeler" P46100 X 77504880-77786233 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001906, CAB009372, HPA064684, CAB068176" Supported Supported "Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "CAB009372: AB_2061023, CAB068176: AB_2665665, HPA001906: AB_1078249, HPA064684: AB_2685321" "unprognostic (1.77e-2)" "unprognostic (1.55e-1)" "unprognostic (6.65e-2)" "unprognostic (4.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.15e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (5.14e-3)" "unprognostic (1.50e-1)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.24e-1)" 18.0 15.9 17.3 17.6 20.4 29.9 18.1 32.9 20.4 18.0 21.4 12.7 11.2 21.2 14.8 13.3 11.8 14.7 15.5 19.2 19.8 16.9 13.2 13.4 22.6 15.0 20.1 24.9 13.4 23.2 8.5 16.6 16.6 19.2 13.5 26.8 14.0 14.8 19.1 15.6 10.9 15.6 16.4 22.8 16.5 6.6 22.6 25.7 20.0 26.9 18.6 14.1 9.9 19.7 36.0 55.1 60.1 45.0 31.8 38.1 21.2 29.4 27.3 21.8 25.9 19.6 30.7 48.5 29.9 32.5 39.9 30.0 44.6 18.1 37.5 27.3 30.8 29.3 67.2 16.2 16.1 38.4 10.2 25.5 20.2 32.2 30.4 29.4 41.9 30.3 34.9 53.3 29.3 27.6 30.2 25.0 42.0 17.6 42.5 48.6 76.3 26.0 25.6 46.4 33.1 55.5 60.5 23.1 21.9 37.2 18.6 20.8 55.8 32.8 76.1 34.4 21.0 16.3 52.9 42.1 23.0 30.9 27.8 44.0 10.5 22.7 26.0 13.3 25.2 31.2 24.0 20.9 8.1 32.4 24.6 20.1 33.2 23.2 20.0 20.7 22.2 9.7 17.3 20.4 32.9 20.4 19.2 19.8 15.0 20.1 16.6 16.4 22.6 19.7 201.0 160.3 230.1 157.4 176.6 92.4 112.2 71.3 114.9 220.1 87.8 86.7 277.8 60.1 101.5 71.7 212.7 72.2 176.9 49.0 23.5 91.8 4.7 103.1 195.5 162.8 126.8 105.8 197.8 83.1 51.0 134.3 114.2 137.3 113.1 261.4 97.8 56.7 70.9 158.2 246.9 78.0 69.2 87.0 101.6 12.7 162.4 113.1 62.2 195.8 149.0 112.3 183.4 202.5 237.1 92.0 47.6 208.0 183.9 120.8 49.2 37.2 102.6 245.4 92.1 174.7 160.0 19.8 52.8 78.7 84.4 59.8 158.0 312.4 73.3 112.0 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1;testis: 30.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.6;Extravillous trophoblasts: 67.1;granulocytes: 54.1;Spermatocytes: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved "Nucleoplasm,Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "Mitotic spindle, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 1.3 2.3 1.3 10.4 1.6 15.3 2.2 2.4 1.4 1.4 0.6 10.8 11.7 1.5 0.8 7.5 1.2 2.0 5.3 0.8 1.0 2.3 5.0 2.2 20.9 1.7 1.2 8.4 2.0 1.8 0.6 8.1 1.4 1.1 12.9 3.0 1.9 1.3 8.7 3.5 9.3 4.9 1.3 5.2 4.9 30.8 1.6 20.2 1.4 8.2 22.1 2.9 2.6 1.3 179.9 127.2 84.5 61.2 4.9 10.8 106.3 145.2 66.8 339.7 142.9 361.4 124.8 58.4 96.2 59.2 176.2 142.2 152.4 96.4 360.0 52.4 57.5 102.6 128.9 229.8 2.8 140.4 140.4 5.1 10.1 117.3 104.5 26.7 80.7 93.2 121.8 45.3 146.9 182.1 85.3 108.9 78.3 145.6 129.8 62.9 163.4 65.9 56.0 46.8 73.9 39.6 200.5 228.8 94.2 77.3 137.9 86.1 47.1 149.7 145.3 83.0 208.6 62.3 78.9 100.5 80.5 80.9 127.0 0.2 3.5 4.3 1.2 5.9 1.8 2.5 2.0 1.1 3.7 0.8 0.9 0.9 2.3 1.4 3.4 0.8 4.7 1.7 1.3 1.6 2.4 1.4 0.8 1.0 1.7 1.2 1.4 1.3 1.6 1.3 2.5 0.0 2.8 0.3 7.4 1.1 1.2 5.6 0.6 1.0 4.3 6.2 5.6 1.5 2.3 3.7 2.1 34.5 8.3 8.3 1.9 4.0 33.9 2.0 2.3 3.1 6.0 81.6 1.1 4.9 67.1 7.0 13.7 3.4 54.1 12.3 3.6 2.6 17.5 1.7 1.5 10.8 2.0 3.5 7.6 16.3 1.5 11.7 0.0 1.0 12.0 3.7 3.1 1.0 2.0 5.2 2.8 0.4 10.1 2.0 5.1 4.2 1.5 2.7 6.6 2.2 7.7 168.2 30.8 8.3 1.1 8.2 8.0 8.7 15.5 1.5 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.1;lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Erythroid cells: 59.3;Extravillous trophoblasts: 89.1;Granulosa cells: 24.7;Hofbauer cells: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.1 1.2 0.1 14.2 0.2 44.1 1.7 0.2 0.2 3.0 0.1 11.1 12.1 1.6 0.4 18.6 0.6 1.5 0.7 0.1 0.2 0.9 2.0 2.5 36.7 0.1 0.3 0.5 0.6 0.3 0.2 8.2 0.3 0.8 11.0 0.0 2.7 0.3 5.5 9.3 11.6 3.2 0.0 12.0 4.6 1.2 0.4 60.1 0.6 0.0 36.6 3.5 5.9 0.2 196.5 130.9 191.1 93.0 4.2 6.5 73.4 91.7 49.5 186.2 170.6 171.5 57.4 193.3 46.2 37.0 77.0 139.8 140.1 62.6 153.7 84.9 231.3 115.7 78.3 146.1 0.7 62.2 109.2 3.5 2.9 109.4 67.7 18.5 86.5 123.6 73.3 73.4 82.9 92.9 225.1 87.4 119.6 63.9 57.6 149.8 176.1 80.5 41.2 38.2 41.2 59.1 81.7 36.5 61.2 56.5 63.5 41.4 33.9 74.3 75.6 67.6 243.3 53.2 37.7 147.9 35.7 92.9 153.4 0.0 0.4 0.6 0.5 0.3 0.1 1.1 1.3 2.1 0.5 2.5 0.1 0.7 0.9 0.3 0.2 0.2 7.9 0.9 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.4 0.2 0.3 0.0 0.5 0.0 7.6 4.5 1.8 6.1 0.6 0.0 1.8 2.2 1.4 0.0 2.6 0.0 0.0 40.5 1.8 13.2 0.0 0.4 0.1 0.5 1.6 3.1 0.0 59.3 0.0 0.0 89.1 5.7 6.1 2.1 4.5 24.7 6.1 0.7 29.4 0.0 0.0 10.8 0.0 5.7 7.3 0.2 0.6 5.1 1.8 0.0 0.9 0.0 3.1 0.0 0.1 0.3 2.8 0.0 15.4 1.2 1.5 0.1 0.2 0.0 0.0 0.1 4.8 1.6 7.2 11.8 2.4 9.0 4.3 1.0 22.0 2.8 AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352723 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012987 Approved Supported Nucleoli,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Vesicles" "CAB012987: AB_2533178" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (7.64e-2)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.23e-2)" "unprognostic (1.03e-1)" 11.9 9.3 10.5 9.2 10.8 23.0 11.5 14.8 12.5 12.9 9.1 17.1 12.3 13.2 3.1 16.3 11.8 6.2 11.6 10.0 9.2 11.6 11.2 13.7 10.5 10.2 10.2 13.8 13.0 7.2 12.6 5.8 9.8 12.9 6.9 2.6 11.5 6.0 21.1 20.1 15.0 5.4 9.2 15.0 12.9 11.8 10.1 12.5 11.9 7.0 6.6 14.5 13.1 11.9 18.1 25.6 13.4 23.7 9.8 9.0 28.0 11.9 10.8 16.1 13.8 37.9 20.4 27.7 18.0 12.3 19.4 25.4 21.1 18.5 7.2 27.5 34.6 18.0 21.9 27.6 16.6 20.9 19.3 9.0 31.7 16.6 20.3 14.1 10.7 19.8 45.6 14.8 7.4 48.1 22.7 14.5 30.6 21.6 15.4 42.4 12.2 38.8 12.2 10.5 30.4 18.6 22.6 24.9 38.3 10.0 16.5 26.1 12.4 15.9 17.0 18.5 17.5 17.3 18.1 34.2 7.5 13.7 15.9 1.2 0.9 5.0 8.3 0.8 7.6 1.5 2.4 5.8 0.7 1.2 2.4 3.4 2.7 3.5 0.6 1.2 2.6 2.3 10.5 10.8 14.8 12.5 10.0 9.2 10.2 10.2 9.8 9.2 10.1 11.9 7.9 3.2 8.6 4.9 5.7 18.4 7.6 8.5 5.7 4.3 11.2 9.5 4.9 5.7 7.2 3.7 0.0 3.5 30.1 27.4 0.0 7.2 1.4 10.2 7.0 6.3 10.8 8.6 18.5 6.9 27.5 6.7 15.3 14.4 10.8 10.5 5.7 5.1 7.5 5.0 12.7 15.1 6.1 6.2 9.0 2.1 5.3 6.7 10.6 1.0 5.7 4.5 28.8 8.5 8.9 11.0 12.2 4.9 7.0 13.4 11.1 2.4 7.7 5.7 13.1 8.7 7.6 5.5 8.8 7.2 15.2 3.7 12.4 5.0 15.7 10.5 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Extravillous trophoblasts: 102.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favorable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 8.7 10.9 6.8 5.4 6.9 0.9 5.3 7.9 7.9 17.2 5.5 12.3 7.1 23.9 5.9 5.9 19.8 6.6 8.0 9.4 6.2 3.7 2.7 17.0 3.5 8.5 7.9 15.0 4.2 4.2 6.2 18.4 5.3 14.0 14.6 3.4 5.2 8.9 14.6 14.9 7.4 17.3 7.3 7.4 13.6 6.7 11.0 17.3 12.3 7.8 2.7 11.4 8.0 5.6 0.0 13.9 27.2 0.5 9.6 4.1 12.0 0.4 1.3 0.9 1.7 52.3 5.0 1.0 1.7 8.0 1.0 0.4 5.7 0.1 1.9 2.4 3.1 0.0 2.4 78.8 1.0 0.1 0.1 2.4 2.1 2.2 0.6 1.6 2.4 5.1 0.2 1.2 1.4 0.3 13.9 0.1 5.3 86.9 0.6 9.9 1.6 0.1 2.6 0.3 8.4 5.5 0.5 0.3 4.8 20.0 1.0 0.3 6.3 5.3 9.6 7.6 1.7 0.1 3.0 3.8 2.5 0.6 2.6 3.2 0.0 0.0 0.1 0.0 0.4 0.5 1.1 0.2 0.0 1.8 2.3 0.4 0.0 1.0 0.0 0.0 0.0 0.3 6.8 6.9 7.9 7.9 9.4 6.2 8.5 7.9 5.3 7.3 11.0 5.6 2.4 0.0 9.0 9.8 1.0 11.2 2.2 1.0 11.4 3.7 5.2 8.1 8.7 1.5 8.1 0.0 4.2 18.1 0.7 15.2 0.0 1.4 33.7 7.8 15.1 5.3 5.4 0.0 8.4 0.9 102.6 10.3 5.6 16.5 0.0 3.1 1.1 2.0 3.8 1.7 8.7 17.4 0.0 0.0 7.5 17.5 6.5 0.6 17.8 9.4 1.0 3.3 0.0 8.0 2.0 0.8 18.9 10.9 0.9 2.9 1.9 0.9 1.3 2.5 13.1 1.6 10.6 6.2 12.9 3.3 5.5 14.2 4.6 3.6 19.8 1.3 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711487-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 31919.3;NK-cells: 24726.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1790000000 2100000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 3160.2 3214.7 697.6 5686.5 705.1 7839.2 2606.9 711.8 1145.0 2539.9 789.6 5139.0 5180.7 2192.2 1735.6 2283.9 1648.3 4948.8 2327.2 651.0 769.9 2462.6 6206.2 6159.2 9311.8 889.5 763.2 1945.7 1310.9 1940.5 318.4 3502.0 815.3 2345.0 5593.5 139.3 5657.1 1784.5 931.7 3015.6 5693.3 2545.3 838.3 7896.1 4878.2 615.6 771.9 4217.4 2340.8 2026.5 5333.4 5753.1 549.4 909.5 1735.4 378.9 226.0 633.6 4348.7 4719.4 1662.5 2045.5 4961.9 3609.7 6561.4 425.3 5417.9 554.8 2567.9 1948.8 2410.2 2537.0 497.2 878.7 1226.2 4762.2 435.9 2956.9 2263.6 600.3 3609.3 2074.5 3328.6 2735.9 609.8 1075.7 1044.4 2442.6 1884.1 965.4 611.9 3649.1 2195.5 476.9 1518.4 3213.8 206.5 629.8 1014.3 2240.2 1926.6 4789.2 2425.5 3486.4 254.1 179.1 1288.4 1571.2 1338.5 394.3 655.3 6180.6 2548.7 4531.4 676.5 5389.2 2193.3 4771.7 7118.6 1683.1 5384.6 3783.6 2567.3 48105.4 18117.1 33178.9 20639.1 17775.0 20836.8 15768.0 23783.0 22245.1 9978.8 11988.4 17122.9 22791.8 50453.6 18779.6 19034.9 12052.6 29659.1 56957.2 697.6 705.1 711.8 1145.0 651.0 769.9 889.5 763.2 815.3 838.3 771.9 909.5 12048.3 3387.8 3505.1 28.7 8472.8 7843.7 3197.1 8420.8 1628.8 33.3 2399.5 2015.2 1068.8 3593.1 5347.4 2100.3 27.1 1354.6 14028.8 8753.6 1038.9 13898.6 43.1 2073.7 2414.0 8385.6 2266.0 2087.2 7.3 9034.5 4397.5 3691.1 1981.7 2282.2 3029.5 1270.6 6835.7 3832.6 11985.7 5.0 22.0 5982.6 8701.4 12536.8 14507.0 158.8 3018.0 10687.9 6744.8 368.2 31919.3 322.0 24726.3 95.0 129.2 10115.7 7085.6 1688.8 11026.6 5300.4 18327.7 3122.5 8367.9 52.5 4016.7 2055.2 4107.1 64.2 72.1 1541.4 8619.8 804.8 14266.2 3229.8 3063.4 8248.6 BAD "BBC2, BCL2L8" ENSG00000002330 "BCL2 associated agonist of cell death" Q92934 11 64269830-64284704 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004205, HPA028185, HPA062105" Approved Enhanced Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB004205: AB_626717, HPA028185: AB_10603445, HPA062105: AB_2684684" "unprognostic (1.47e-1)" "unprognostic (3.08e-2)" "unprognostic (1.17e-1)" "unprognostic (8.24e-3)" "unprognostic (2.60e-1)" "unprognostic (6.73e-2)" "unprognostic (1.24e-3)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (8.26e-2)" "unprognostic (9.04e-2)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (7.95e-2)" 60.8 85.1 94.0 13.2 91.1 23.3 58.8 89.0 133.1 64.9 86.6 81.7 26.5 64.8 12.7 72.9 58.8 15.5 118.0 93.1 87.8 87.6 96.1 58.7 14.7 93.4 92.7 55.2 53.7 35.6 55.3 21.7 89.4 79.7 15.1 17.2 57.7 27.6 50.7 70.6 44.7 14.0 89.9 45.0 87.1 55.1 98.9 17.2 75.8 15.1 12.4 65.9 57.7 92.7 95.0 85.1 25.2 38.3 30.0 36.4 36.9 38.2 45.9 60.0 47.5 54.8 53.1 19.5 67.7 37.4 46.9 49.9 16.8 62.7 11.9 77.6 58.7 24.9 81.4 26.1 45.9 20.7 45.0 35.3 53.7 45.8 28.3 45.9 37.5 44.1 10.1 42.9 26.6 94.7 49.8 49.7 9.8 27.7 109.6 46.7 13.8 57.9 36.8 44.3 51.2 67.1 39.2 46.8 49.9 9.6 70.5 32.0 30.3 72.8 48.1 112.8 43.8 79.6 64.0 21.3 59.2 15.6 40.6 88.0 69.7 102.3 52.9 56.7 54.7 58.6 55.4 51.9 50.5 57.5 39.8 40.9 92.4 59.5 55.3 94.0 71.8 51.4 94.0 91.1 89.0 133.1 93.1 87.8 93.4 92.7 89.4 89.9 98.9 92.7 56.3 32.1 45.1 7.8 32.9 103.1 54.1 170.2 51.2 67.7 76.7 74.8 51.6 70.1 66.4 53.3 18.8 162.5 32.4 214.4 137.0 101.2 43.5 71.5 64.8 56.8 104.1 69.2 10.4 109.9 197.8 75.3 53.0 45.4 24.1 58.2 62.4 51.0 73.8 47.1 7.5 141.8 89.5 24.1 72.6 93.3 74.3 32.9 110.3 2.8 52.4 95.9 36.0 4.0 8.9 120.7 210.0 85.4 33.2 62.1 138.1 152.8 83.2 52.0 59.2 36.2 72.6 69.5 25.0 57.7 119.1 255.0 36.0 57.8 117.1 63.4 BAG1 ENSG00000107262 "BAG cochaperone 1" Q99933 9 33247820-33264720 "Cancer-related genes, Predicted intracellular proteins" Apoptosis Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1043.2;Late spermatids: 2944.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 437.5;NB-4: 417.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002486, HPA018121, HPA073236" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB002486: AB_563422, HPA018121: AB_1845255, HPA073236: " "unprognostic (4.49e-3)" "unprognostic (4.52e-2)" "unprognostic (2.33e-2)" "unprognostic (1.32e-3)" "unprognostic (5.46e-2)" "unprognostic (3.67e-3)" "unprognostic (2.10e-1)" "unprognostic (1.34e-2)" "unprognostic (4.62e-2)" "unprognostic (7.21e-2)" "unprognostic (4.24e-1)" "unprognostic (2.23e-1)" "prognostic favorable (2.22e-16)" "unprognostic (4.45e-2)" "unprognostic (4.03e-1)" "unprognostic (7.64e-3)" "unprognostic (1.07e-2)" 79.7 76.3 96.6 36.3 106.7 85.0 72.3 102.2 112.3 65.0 106.0 122.5 59.3 59.8 53.9 103.2 54.8 39.1 192.9 86.4 102.8 151.6 83.4 82.5 35.5 107.4 105.2 45.6 91.7 139.6 99.3 47.1 98.8 88.0 75.4 82.2 97.4 68.4 297.7 113.8 66.1 42.7 100.2 66.0 102.5 87.9 104.3 45.1 71.6 206.1 55.2 121.5 78.8 101.6 56.0 56.1 46.8 103.3 69.9 40.9 63.6 46.5 64.6 68.4 69.8 39.7 54.1 181.2 33.6 46.6 24.5 69.8 54.8 37.9 45.0 96.5 52.1 90.2 437.5 62.5 58.9 210.1 110.0 41.5 205.6 32.3 76.8 32.2 82.4 48.0 108.7 92.1 57.8 89.7 152.4 417.0 90.8 73.9 81.2 78.7 63.7 119.6 87.1 164.8 149.1 88.5 192.7 176.9 46.0 18.7 80.5 261.8 44.1 30.5 37.8 89.9 78.0 74.9 125.3 100.4 25.5 114.1 17.7 29.1 20.7 57.9 10.0 22.2 9.0 14.7 11.2 11.9 26.1 25.6 15.7 9.1 10.2 15.3 22.3 33.9 15.2 10.2 96.6 106.7 102.2 112.3 86.4 102.8 107.4 105.2 98.8 100.2 104.3 101.6 107.7 89.8 67.5 5.2 69.4 429.9 279.4 193.3 172.4 84.0 134.1 123.6 144.4 127.2 157.0 218.8 58.4 154.7 113.7 211.4 397.2 135.6 1043.2 109.3 72.2 86.6 198.1 259.1 5.9 189.0 59.9 79.4 104.5 193.3 41.9 36.7 66.8 72.8 104.9 38.7 7.1 287.8 170.9 86.4 162.7 2944.9 85.7 93.9 163.7 2.8 81.0 123.9 88.6 4.5 9.7 131.1 259.2 88.8 110.3 505.4 247.9 286.1 71.8 131.3 98.6 98.5 109.9 87.9 64.4 261.1 561.5 245.9 69.6 103.7 222.4 531.4 BAP1 "hucep-6, KIAA0272, UCHL2" ENSG00000163930 "BRCA1 associated protein 1" Q92560 3 52401008-52410008 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 103.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004322, HPA028814, HPA028815, HPA055560" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB004322: AB_626723, HPA028814: AB_10602393, HPA028815: AB_2672785, HPA055560: AB_2682850" "unprognostic (1.52e-1)" "unprognostic (7.96e-2)" "unprognostic (1.96e-2)" "unprognostic (6.04e-2)" "unprognostic (1.74e-1)" "unprognostic (2.55e-2)" "unprognostic (9.41e-3)" "unprognostic (8.53e-3)" "unprognostic (1.33e-1)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.30e-3)" "prognostic favorable (3.29e-7)" "unprognostic (6.37e-2)" "unprognostic (1.91e-1)" "unprognostic (5.54e-2)" "unprognostic (2.92e-1)" 45.2 63.5 97.6 25.0 99.2 73.9 42.9 78.9 135.5 39.1 71.4 47.7 21.6 40.5 23.1 59.3 36.0 25.7 57.0 114.1 83.3 57.3 65.2 46.0 29.4 81.2 85.7 43.9 52.7 40.2 36.9 24.6 81.7 50.0 24.1 20.1 43.0 22.5 74.7 73.4 43.4 23.8 79.9 54.2 48.1 140.0 89.2 33.1 49.1 43.5 27.9 44.6 41.7 90.5 39.1 43.1 52.2 44.8 50.1 31.4 59.3 37.8 50.1 62.4 48.0 52.5 35.8 55.7 18.3 54.7 69.3 31.4 55.7 63.0 37.9 55.1 51.4 68.6 94.4 53.2 45.7 65.6 58.5 48.0 80.1 68.5 36.1 33.3 50.3 107.7 59.9 48.3 44.5 33.7 79.1 89.5 58.0 31.0 52.8 33.7 41.7 55.8 37.4 61.2 19.8 63.6 46.1 13.7 56.9 29.2 37.7 90.6 52.5 54.1 49.3 66.0 70.9 71.7 101.6 81.2 58.5 68.2 66.1 2.9 3.2 5.4 5.4 2.8 2.6 3.2 4.3 4.4 2.2 4.1 3.1 4.0 7.4 2.2 2.2 5.6 4.2 2.7 97.6 99.2 78.9 135.5 114.1 83.3 81.2 85.7 81.7 79.9 89.2 90.5 13.5 0.0 16.0 8.1 12.2 31.6 10.5 13.2 23.3 16.6 16.4 12.6 23.6 11.5 10.2 25.8 0.0 14.0 17.7 23.2 11.7 13.5 103.4 9.2 12.4 14.7 10.8 8.2 7.5 16.7 15.8 13.6 14.8 13.6 21.0 18.1 14.6 29.2 12.6 10.1 7.7 16.6 6.1 17.4 10.7 48.0 10.2 12.0 12.4 5.6 15.2 16.1 16.5 7.1 6.7 15.8 16.5 11.7 16.2 11.7 13.3 18.5 8.2 12.3 19.7 14.7 14.2 37.8 13.9 23.0 23.4 12.0 12.2 15.9 19.8 9.6 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BAX BCL2L4 ENSG00000087088 "BCL2 associated X, apoptosis regulator" Q07812 19 48954815-48961798 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004206, HPA027878" Approved NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "CAB004206: AB_626729, HPA027878: AB_10601687" "unprognostic (4.11e-2)" "unprognostic (4.70e-2)" "unprognostic (1.50e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (1.63e-5)" "unprognostic (4.92e-2)" "unprognostic (1.09e-1)" "unprognostic (4.71e-2)" "unprognostic (3.66e-2)" "unprognostic (8.10e-2)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (1.08e-1)" "unprognostic (4.47e-3)" "unprognostic (6.22e-2)" 30.2 30.4 24.4 59.2 26.8 65.7 27.2 25.5 29.3 27.6 23.9 78.1 68.2 29.9 23.2 35.8 33.2 37.6 22.6 24.5 25.5 31.0 33.4 46.0 59.5 27.1 25.4 19.6 32.7 26.1 15.9 43.3 27.0 25.7 58.8 7.2 26.5 27.0 18.1 29.8 64.6 36.3 26.1 60.0 43.8 12.4 26.3 83.2 23.4 11.8 44.7 46.7 26.1 27.1 177.4 286.0 170.1 150.4 165.4 161.7 280.2 117.8 233.4 151.7 210.6 76.4 168.6 214.6 53.9 181.2 141.3 93.8 78.0 229.0 125.7 166.6 181.0 91.9 56.6 288.0 265.7 96.3 280.9 222.3 161.7 126.1 75.5 183.3 354.6 83.4 91.4 86.0 264.8 123.1 157.6 150.3 132.8 171.3 82.5 109.2 113.1 82.4 161.0 168.4 97.4 114.7 99.2 69.8 57.4 240.6 56.2 171.2 210.2 194.0 212.1 120.1 165.1 97.9 136.6 145.0 118.1 129.2 275.1 5.2 12.1 13.4 6.5 18.4 4.6 7.3 3.7 7.1 12.2 5.9 2.4 6.0 13.1 12.2 20.9 12.5 7.5 8.4 24.4 26.8 25.5 29.3 24.5 25.5 27.1 25.4 27.0 26.1 26.3 27.1 83.2 3.2 4.8 8.1 164.6 54.8 63.8 160.8 101.3 19.3 64.1 67.4 8.4 78.6 98.7 60.7 10.4 126.0 130.2 152.9 74.3 122.7 1.1 43.4 65.7 83.7 114.0 79.3 7.9 96.2 157.9 57.0 114.2 46.0 43.9 151.7 59.3 28.1 263.6 30.3 8.3 102.7 209.5 121.8 143.0 4.0 48.1 148.3 83.6 3.7 295.3 43.9 140.1 7.5 13.8 139.4 177.0 38.4 96.2 126.6 229.8 227.4 66.4 15.9 46.0 35.8 259.4 20.3 38.1 92.0 56.4 101.9 149.4 175.5 149.7 86.7 BCL10 "c-E10, CARMEN, CIPER, CLAP, mE10" ENSG00000142867 "BCL10 immune signaling adaptor" O95999 1 85265776-85276632 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 194.1;Paneth cells: 210.2;Urothelial cells: 297.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 97.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001944, HPA017925" Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB001944: , HPA017925: AB_1845312" "unprognostic (3.78e-3)" "unprognostic (2.53e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.61e-2)" "prognostic unfavorable (7.21e-7)" "unprognostic (7.06e-2)" "unprognostic (2.36e-1)" "unprognostic (9.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.73e-1)" "unprognostic (4.92e-3)" "unprognostic (3.18e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (1.07e-1)" 10.1 7.4 4.3 13.8 4.6 24.3 10.6 5.3 6.8 14.7 6.0 26.7 14.7 8.1 7.9 18.1 9.0 18.9 5.5 5.3 4.4 8.7 9.8 9.2 13.7 4.8 4.6 7.2 8.9 6.2 2.6 9.3 4.4 7.8 23.5 2.7 8.5 5.1 6.7 9.4 16.5 11.8 4.7 11.6 14.9 6.5 5.8 9.4 9.0 5.7 16.4 23.1 11.3 5.5 38.5 7.6 11.6 11.8 13.7 23.7 16.9 26.8 27.6 20.9 27.8 8.1 14.5 14.5 19.1 22.5 39.3 19.6 12.8 32.4 28.7 14.8 8.2 16.9 6.5 11.9 24.0 16.7 15.4 18.6 31.7 31.4 25.6 24.5 97.9 10.0 11.7 14.1 33.2 6.8 16.4 13.5 19.0 22.1 25.0 12.2 21.8 9.8 71.2 29.2 6.3 8.5 8.2 28.6 23.2 14.8 9.6 10.2 47.3 19.0 13.2 24.1 27.5 11.7 6.5 16.6 9.9 13.1 14.7 78.4 34.1 48.2 20.8 41.8 23.5 46.7 27.0 24.4 33.7 41.4 24.7 23.5 85.0 24.6 33.1 26.3 31.1 22.9 4.3 4.6 5.3 6.8 5.3 4.4 4.8 4.6 4.4 4.7 5.8 5.5 40.6 22.4 18.1 3.3 49.6 194.1 167.2 75.4 48.3 5.7 29.2 19.8 4.6 17.2 54.9 23.9 0.0 16.0 24.1 174.3 17.6 71.5 85.1 97.7 36.1 48.2 49.0 9.1 8.8 44.7 28.4 24.9 57.1 152.2 39.3 17.9 28.2 19.8 21.2 10.1 6.1 79.7 38.7 31.8 68.8 13.4 11.1 41.7 16.0 2.8 21.7 11.1 11.3 9.5 6.1 74.1 210.2 11.3 25.0 80.0 45.2 25.4 32.9 6.3 0.0 19.9 21.8 9.7 12.9 76.7 171.3 23.7 31.3 21.5 77.2 297.4 BCL11A "BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856" ENSG00000119866 "BAF chromatin remodeling complex subunit BCL11A" Q9H165 2 60450520-60554467 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.8;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "B-cells: 149.0;Basal squamous epithelial cells: 118.4;dendritic cells: 140.3;Excitatory neurons: 180.8;Inhibitory neurons: 153.2;Squamous epithelial cells: 120.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 312.7;naive B-cell: 415.7;plasmacytoid DC: 899.0" "Group enriched" "Detected in all" 15 "B-cells: 415.7;dendritic cells: 899.0" "Cell line enhanced" "Detected in many" "Daudi: 51.1;MOLT-4: 49.0;REH: 48.3;U-698: 106.7;U-937: 34.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 52.5;cerebral cortex: 82.3;hippocampal formation: 69.2;olfactory bulb: 66.7" "CAB014891, HPA029003, HPA075941" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "CAB014891: , HPA029003: AB_2672863, HPA075941: " "unprognostic (4.10e-3)" "unprognostic (6.72e-2)" "unprognostic (4.50e-2)" "unprognostic (9.41e-3)" "unprognostic (2.37e-1)" "unprognostic (4.47e-3)" "unprognostic (2.53e-2)" "unprognostic (1.68e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (4.27e-4)" "unprognostic (1.23e-2)" "unprognostic (2.35e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-1)" "unprognostic (4.40e-2)" "unprognostic (2.99e-2)" 0.7 2.1 31.4 11.3 34.7 25.3 7.1 10.5 47.8 5.2 9.7 18.4 9.7 2.1 1.4 18.4 5.7 2.5 8.0 38.7 15.5 1.0 0.5 2.1 29.2 31.6 15.3 0.6 10.8 1.7 3.0 0.9 31.0 7.8 6.1 1.7 13.8 1.9 1.7 33.2 13.9 3.4 15.9 19.6 4.8 2.0 15.9 33.9 2.3 0.2 40.9 3.3 11.5 38.7 0.6 0.0 4.2 0.1 0.8 0.8 0.3 1.5 0.0 0.1 0.0 0.0 0.2 51.1 0.2 0.2 0.0 10.5 15.4 7.4 0.2 0.9 15.2 0.1 0.6 0.2 0.0 18.7 0.1 1.7 4.1 0.0 2.5 4.0 2.6 17.1 0.8 0.3 0.1 0.1 49.0 19.9 28.6 7.7 0.2 48.3 1.3 19.7 0.0 0.9 20.1 4.8 0.3 0.4 0.3 8.0 0.3 9.1 1.0 0.3 11.6 0.3 0.1 0.8 0.2 106.7 0.1 34.0 1.6 4.5 23.8 5.1 0.5 44.1 1.1 312.7 0.5 0.5 89.9 415.7 1.3 1.1 11.0 8.4 33.7 899.0 1.1 11.4 31.4 34.7 10.5 47.8 38.7 15.5 31.6 15.3 31.0 15.9 15.9 38.7 0.6 0.0 7.4 3.6 149.0 46.3 16.0 34.0 118.4 2.5 31.6 28.6 18.2 4.3 11.7 1.8 0.0 0.6 140.3 7.5 5.9 9.5 12.0 3.9 2.0 1.4 19.8 69.6 180.8 6.4 0.5 3.6 5.1 4.8 10.1 67.4 0.7 0.1 43.2 52.2 153.2 13.6 6.1 7.0 86.1 5.0 0.3 20.5 16.0 11.2 16.0 0.3 0.0 3.5 4.6 4.7 12.5 0.0 6.0 11.7 16.2 0.5 5.5 0.3 0.0 0.2 2.0 2.9 6.9 120.3 69.9 0.8 4.6 1.0 28.9 5.8 BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.8;Basal squamous epithelial cells: 73.4;Excitatory neurons: 57.5;Inhibitory neurons: 105.7;NK-cells: 51.5;Suprabasal keratinocytes: 71.3;T-cells: 133.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "JURKAT: 38.3;MOLT-4: 47.3" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" 0.4 0.3 8.0 5.1 21.2 4.9 1.1 0.0 17.2 0.9 0.0 1.2 2.0 0.2 0.5 4.3 0.3 0.9 0.1 18.9 1.1 0.3 0.4 1.1 10.2 0.3 0.8 0.2 0.1 0.0 0.2 0.1 0.0 0.5 1.4 0.0 1.7 0.3 0.2 15.0 3.5 0.2 1.5 4.4 1.9 0.5 2.0 36.6 0.8 0.0 7.5 1.3 2.9 3.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 1.7 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.2 0.0 0.0 38.3 0.0 4.1 0.0 2.8 47.3 0.8 0.5 3.6 0.0 7.0 0.0 0.0 0.0 2.6 3.7 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.7 0.2 0.0 2.6 0.1 0.0 2.0 0.7 0.0 0.0 0.0 0.1 2.0 0.0 1.8 0.0 2.8 2.4 0.0 0.0 4.6 3.1 0.0 0.3 0.0 0.0 2.0 0.8 8.0 21.2 0.0 17.2 18.9 1.1 0.3 0.8 0.0 1.5 2.0 3.9 1.3 3.2 0.0 1.3 6.4 62.8 1.6 6.3 73.4 0.4 4.3 4.4 3.8 4.3 1.3 0.0 0.0 0.1 44.2 3.8 1.9 0.2 0.2 0.2 0.2 1.2 1.2 5.3 57.5 0.5 0.0 3.3 2.0 0.3 5.1 0.2 3.3 0.3 0.3 0.0 105.7 4.9 2.0 1.0 11.4 0.4 0.6 4.0 5.4 1.0 4.9 0.0 51.5 32.2 2.0 1.1 5.4 0.0 24.4 0.6 10.1 0.5 0.3 0.1 0.0 0.5 1.9 1.6 5.8 42.7 71.3 0.0 133.4 0.1 9.7 0.6 BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Inhibitory neurons: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.5" "Cell line enhanced" "Detected in many" "HDLM-2: 44.2;HL-60: 43.7;Karpas-707: 72.9;U-266/70: 217.4" "Low region specificity" "Detected in all" "CAB000003, HPA055295" Enhanced Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "CAB000003: AB_2064429, HPA055295: AB_2682776" "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" 12.8 1.9 5.5 10.2 7.8 5.0 9.6 4.7 3.4 10.7 0.0 6.2 4.4 11.6 2.9 5.9 11.8 6.5 5.3 2.9 6.6 6.7 2.1 3.7 14.7 11.2 7.9 14.5 3.1 13.0 4.7 4.6 7.5 6.4 5.5 2.1 3.7 7.0 16.5 4.8 8.1 6.6 7.9 17.9 3.8 1.5 8.2 18.3 24.0 8.8 14.6 5.4 7.7 5.7 1.7 0.3 6.8 5.9 6.7 1.3 2.4 1.0 0.7 2.4 2.0 3.5 0.4 0.3 1.1 0.9 4.7 0.4 6.7 0.9 1.5 44.2 1.6 0.5 2.0 0.7 2.0 43.7 5.6 1.7 0.8 3.3 5.8 1.1 0.7 4.3 0.8 72.9 2.2 1.4 9.8 10.7 1.5 0.8 1.3 39.5 1.9 26.5 7.4 8.5 7.2 6.4 0.3 0.3 8.5 1.4 0.3 29.9 0.3 9.9 3.3 0.9 5.1 217.4 40.1 2.9 1.9 24.9 6.0 0.3 0.0 0.0 1.9 0.0 7.6 5.4 6.3 3.4 0.1 3.1 3.3 3.2 0.0 0.2 0.3 0.2 8.5 1.3 5.5 7.8 4.7 3.4 2.9 6.6 11.2 7.9 7.5 7.9 8.2 5.7 7.1 0.0 1.1 271.6 84.9 19.5 33.6 1.6 13.6 1.9 39.7 19.7 17.4 18.6 2.4 7.3 0.0 14.0 39.9 2.7 15.6 3.7 0.4 9.8 9.8 5.9 5.4 3.8 60.7 0.0 0.7 15.8 5.6 24.9 15.8 38.8 3.9 1.2 9.4 0.0 102.3 10.5 24.4 15.0 29.6 1.9 8.7 29.0 46.2 88.1 19.7 18.8 18.6 76.4 56.7 0.2 5.9 13.9 50.1 41.6 0.9 18.0 0.1 0.6 26.3 48.8 19.7 0.3 1.3 6.2 17.6 49.1 76.1 24.1 9.8 76.2 BCL2A1 "ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1" ENSG00000140379 "BCL2 related protein A1" Q16548 15 79960892-79971196 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 617.3" "Group enriched" "Detected in many" 5 "B-cells: 177.4;granulocytes: 220.7;Hofbauer cells: 214.9;Langerhans cells: 508.2;Macrophages: 604.2;monocytes: 386.0" "Cancer enhanced" "Detected in all" "melanoma: 39.4" "Group enriched" "Detected in all" 4 "cerebral cortex: 39.7;pons: 12.5" "Group enriched" "Detected in all" 5 "eosinophil: 284.0;intermediate monocyte: 195.8;neutrophil: 534.0;non-classical monocyte: 378.9" "Group enriched" "Detected in all" 7 "granulocytes: 534.0;monocytes: 378.9" "Cell line enriched" "Detected in many" 5 "SK-MEL-30: 525.0" "Low region specificity" "Detected in single" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "unprognostic (3.19e-3)" "unprognostic (2.61e-1)" "unprognostic (3.99e-2)" "unprognostic (3.54e-3)" "unprognostic (9.65e-3)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-1)" "unprognostic (1.78e-2)" "unprognostic (4.01e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (4.61e-2)" "unprognostic (8.96e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" 28.6 1.7 2.5 105.1 2.7 617.3 4.3 2.8 39.7 4.3 4.3 5.9 4.6 2.8 1.5 2.4 8.4 17.4 4.6 2.4 2.7 3.4 14.7 59.0 72.0 4.9 3.9 0.9 4.7 0.9 1.3 20.4 12.5 2.3 5.9 0.6 4.4 0.9 0.9 1.7 8.0 13.5 3.4 57.9 5.6 0.4 6.3 17.2 2.4 10.8 56.7 52.1 1.7 5.8 0.4 1.4 0.0 0.1 0.6 0.9 0.0 0.0 6.9 0.0 0.6 0.0 0.1 3.0 0.2 0.0 0.2 0.0 0.0 14.3 4.1 1.5 0.0 0.6 0.0 1.4 2.2 3.7 111.4 2.0 0.1 8.2 0.0 0.2 0.7 0.6 0.0 0.4 0.2 0.0 0.1 19.3 0.1 0.0 3.5 0.2 0.1 0.2 0.6 0.1 0.0 0.1 0.0 0.0 525.0 0.0 0.0 5.0 0.0 51.8 4.9 0.2 1.1 0.5 0.3 4.3 2.3 40.3 27.4 24.2 42.3 284.0 24.5 195.8 13.9 64.4 31.3 32.4 25.2 44.2 38.1 35.1 534.0 21.5 378.9 5.0 8.0 49.1 2.5 2.7 2.8 39.7 2.4 2.7 4.9 3.9 12.5 3.4 6.3 5.8 7.6 22.4 57.3 0.0 177.4 11.0 0.8 50.9 0.6 0.1 2.9 3.7 4.3 0.0 38.0 1.8 0.0 1.9 33.9 0.3 1.9 2.2 1.3 12.0 4.2 6.2 0.0 1.3 0.1 1.6 2.3 8.4 2.0 41.1 220.7 0.2 1.4 1.6 214.9 0.0 0.1 0.1 2.0 60.5 508.2 1.5 0.0 604.2 33.8 0.0 386.0 0.3 13.4 0.0 0.0 6.5 0.1 0.0 14.6 1.4 0.1 0.8 13.8 0.2 0.0 1.3 4.8 0.3 0.2 0.5 10.2 4.5 53.3 0.1 0.2 1.8 BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 160.0;Pancreatic endocrine cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB072801: , HPA035734: AB_2674757" "unprognostic (2.29e-1)" "unprognostic (5.40e-3)" "unprognostic (1.78e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (5.04e-2)" "unprognostic (7.82e-3)" "prognostic favorable (9.57e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (1.06e-1)" "prognostic favorable (8.89e-5)" "unprognostic (9.67e-2)" "unprognostic (3.03e-2)" "unprognostic (2.02e-2)" "unprognostic (3.32e-2)" 80.3 46.9 46.3 26.1 53.7 99.0 71.0 46.7 54.5 46.5 88.2 42.4 49.4 39.2 11.9 77.8 42.7 51.7 77.9 42.2 48.2 95.7 85.2 95.1 25.8 49.5 49.4 23.1 54.7 30.4 49.8 42.0 51.1 52.0 26.2 41.0 70.6 25.2 55.4 65.7 48.9 25.0 41.3 53.4 66.6 46.2 54.4 111.5 51.4 38.8 28.9 42.8 54.7 59.7 327.0 188.4 30.7 32.4 167.8 123.1 101.0 73.8 113.2 69.6 66.4 429.2 150.9 48.2 176.7 108.4 140.7 105.8 42.9 216.7 46.2 55.1 8.6 231.3 34.4 231.6 123.0 19.6 137.7 90.7 77.4 89.4 194.0 102.4 106.0 81.6 150.0 34.5 238.7 94.3 73.9 20.6 45.4 150.8 153.2 43.5 92.9 164.3 249.3 83.4 85.4 38.4 89.3 92.6 42.4 57.2 180.5 26.3 154.1 90.0 109.1 36.8 139.4 22.7 150.7 37.9 143.5 99.5 59.5 28.6 11.0 25.6 39.9 11.7 30.9 4.8 17.1 26.8 10.4 6.0 7.7 18.6 12.5 19.8 13.4 7.0 21.8 28.2 46.3 53.7 46.7 54.5 42.2 48.2 49.5 49.4 51.1 41.3 54.4 59.7 41.6 16.0 9.2 22.5 10.1 18.4 70.2 40.8 26.7 21.9 25.5 15.4 9.7 91.5 36.3 38.6 45.9 27.1 13.7 41.7 86.1 92.2 10.2 71.4 14.6 35.8 24.7 160.0 21.8 65.9 11.3 15.5 37.2 58.2 12.7 10.6 36.4 40.8 38.2 28.6 19.5 26.0 69.2 22.1 13.3 4.6 19.0 27.6 17.8 49.6 76.9 24.1 54.6 13.6 55.6 187.7 22.4 42.9 38.0 102.9 54.6 76.5 76.4 33.7 46.0 14.9 42.7 31.0 15.1 13.6 9.8 18.9 24.9 13.6 19.6 143.0 BCL2L2 "BCL-W, KIAA0271, PPP1R51" ENSG00000129473 "BCL2 like 2" Q92843 14 23298790-23311751 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040539, HPA048740" Approved Uncertain Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB040539: , HPA048740: " "unprognostic (8.23e-3)" "unprognostic (9.85e-2)" "unprognostic (1.71e-2)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (1.64e-1)" "unprognostic (3.47e-3)" "unprognostic (1.53e-2)" "unprognostic (1.78e-1)" "unprognostic (2.91e-3)" "unprognostic (1.50e-3)" "unprognostic (2.60e-1)" "prognostic favorable (1.99e-6)" "unprognostic (2.44e-1)" "unprognostic (2.00e-1)" "unprognostic (6.60e-2)" "unprognostic (5.38e-2)" 48.5 36.6 102.4 26.0 95.3 13.9 35.6 83.7 112.4 30.2 61.8 86.9 28.5 43.0 30.5 46.8 35.4 24.7 37.3 89.8 88.8 35.0 20.9 34.6 13.9 94.8 94.0 31.8 53.3 52.9 38.1 23.8 91.7 47.4 31.8 51.9 52.2 45.5 24.2 46.5 34.3 41.5 101.0 20.5 54.2 25.1 108.3 10.7 38.5 19.9 16.4 55.6 34.9 92.4 24.1 23.0 25.6 19.0 43.4 39.2 19.3 43.9 28.5 21.8 24.9 16.3 42.6 16.8 14.2 26.6 27.4 43.9 15.9 28.1 29.4 8.9 12.7 18.4 44.4 30.3 26.6 20.7 30.0 30.3 54.0 17.6 27.1 30.6 18.6 2.9 17.3 18.0 27.8 17.8 1.6 14.5 8.0 33.4 41.3 12.8 28.1 8.2 19.7 45.5 31.7 18.0 20.8 31.3 31.2 15.6 20.6 15.5 37.1 35.1 24.8 27.6 23.1 22.0 12.7 2.2 21.6 16.0 43.5 0.0 0.4 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.3 102.4 95.3 83.7 112.4 89.8 88.8 94.8 94.0 91.7 101.0 108.3 92.4 9.2 9.6 13.1 0.0 2.6 8.7 9.5 12.7 5.7 20.0 11.0 8.0 28.9 4.3 13.6 5.5 25.0 5.3 3.5 16.8 13.7 8.0 20.1 11.1 10.4 10.8 18.6 2.1 0.0 18.3 4.0 10.4 9.7 12.1 5.7 12.0 11.4 7.2 5.5 20.2 0.0 16.8 6.1 8.4 4.0 6.1 11.1 5.5 7.2 0.0 7.5 7.4 2.1 0.0 0.0 25.5 11.0 21.4 4.5 17.2 16.3 9.2 12.2 12.7 6.6 12.6 15.5 0.5 0.9 10.8 11.1 5.6 1.5 8.9 10.5 17.6 BCL2L2-PABPN1 ENSG00000258643 "BCL2L2-PABPN1 readthrough" Q92843 14 23306833-23326175 "Cancer-related genes, Predicted intracellular proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Excitatory neurons: 10.9;Inhibitory neurons: 14.4;Oligodendrocyte precursor cells: 16.6;Oligodendrocytes: 13.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000637, HPA048740" Approved Uncertain "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear speckles" "HPA000637: AB_1079553, HPA048740: " "unprognostic (1.32e-2)" "unprognostic (8.74e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-3)" "unprognostic (9.82e-3)" "unprognostic (2.85e-2)" "unprognostic (1.05e-6)" "unprognostic (4.39e-2)" "unprognostic (1.67e-1)" "unprognostic (1.84e-3)" "unprognostic (7.61e-2)" "unprognostic (3.47e-2)" "unprognostic (1.72e-7)" "unprognostic (3.13e-2)" "unprognostic (8.77e-2)" "unprognostic (3.46e-3)" "unprognostic (4.95e-2)" 8.2 4.1 8.8 4.2 10.8 10.7 9.6 7.2 20.6 10.9 1.3 17.2 10.4 8.3 2.0 11.6 10.8 10.9 7.2 9.8 8.3 3.5 4.2 7.3 4.3 8.7 9.3 4.6 12.4 8.0 7.1 10.9 9.0 12.1 6.3 5.6 24.9 22.1 4.8 11.0 8.8 7.7 10.1 6.0 10.3 12.5 11.7 1.2 8.7 0.9 4.1 13.4 7.5 15.8 11.4 18.0 15.2 31.3 15.3 29.3 14.0 13.4 27.3 39.8 44.2 10.1 38.0 3.5 4.0 21.2 22.5 24.2 16.9 21.4 17.9 8.5 21.6 4.7 11.2 26.0 14.5 10.0 29.7 37.4 29.7 17.6 6.1 27.3 14.7 0.2 8.2 8.2 19.3 18.1 0.4 7.5 17.3 10.3 18.2 7.9 4.0 5.9 10.3 10.1 16.0 10.0 9.8 22.6 15.2 10.8 8.7 8.2 15.4 18.7 8.4 17.1 12.8 4.9 6.6 1.1 25.2 10.5 19.4 0.8 2.5 0.1 0.1 1.2 0.0 0.5 0.0 0.0 0.8 1.0 0.1 0.0 0.5 1.6 1.4 0.4 0.0 0.6 8.8 10.8 7.2 20.6 9.8 8.3 8.7 9.3 9.0 10.1 11.7 15.8 0.0 3.2 3.9 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 10.9 0.0 0.0 0.7 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.8 0.0 0.0 0.0 16.6 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 172.4;Squamous epithelial cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Cell line enhanced" "Detected in many" "HDLM-2: 67.3;Karpas-707: 54.1;SiHa: 69.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002051, HPA047514" Approved Supported Nucleoplasm,Vesicles,Midbody Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Vesicles, Midbody" "CAB002051: AB_563428, HPA047514: AB_2680074" "prognostic favorable (9.67e-4)" "unprognostic (8.82e-2)" "unprognostic (2.81e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (3.49e-2)" "unprognostic (2.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.74e-4)" "unprognostic (2.09e-2)" "unprognostic (9.23e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.13e-14)" "unprognostic (8.24e-2)" "unprognostic (1.36e-1)" "unprognostic (3.77e-2)" "unprognostic (3.04e-2)" 65.1 43.6 6.7 25.0 6.3 54.0 37.2 6.4 7.8 26.8 7.9 39.7 32.2 26.8 1.7 67.5 35.9 13.4 36.3 5.9 7.2 56.6 161.8 87.3 11.6 11.6 7.8 23.7 37.4 3.1 25.2 7.9 8.1 43.4 9.3 1.3 40.9 8.9 17.8 28.3 44.2 11.7 8.0 58.7 35.9 9.6 8.5 6.6 36.8 4.9 12.7 37.6 37.7 6.4 9.8 33.5 0.7 17.5 6.1 12.6 1.7 5.8 6.3 3.7 5.3 6.9 17.8 9.5 13.4 11.5 18.5 10.5 2.4 9.9 2.3 67.3 0.6 1.1 18.9 9.3 14.6 0.7 28.2 22.5 7.8 8.1 9.9 16.6 10.0 0.0 1.2 54.1 2.2 8.4 0.0 7.4 0.9 15.1 12.8 4.3 6.5 3.4 16.5 19.9 0.0 0.9 69.7 35.7 1.9 1.1 12.7 7.6 16.8 11.8 11.6 18.5 2.2 50.1 21.4 10.1 22.1 1.2 9.2 0.4 2.7 5.5 0.8 1.8 1.1 1.5 1.0 1.3 2.6 1.3 0.5 0.7 19.8 2.3 1.1 3.1 1.7 1.0 6.7 6.3 6.4 7.8 5.9 7.2 11.6 7.8 8.1 8.0 8.5 6.4 56.3 19.2 51.3 2.6 43.9 46.7 38.8 22.4 172.4 2.3 106.8 62.0 3.0 42.9 28.6 12.9 0.0 0.6 33.4 60.6 9.8 31.8 11.8 49.4 34.2 76.3 21.5 4.2 0.5 68.7 6.8 47.8 128.0 70.0 38.0 1.4 38.9 35.5 16.1 8.4 0.8 56.2 8.2 30.5 110.8 2.7 13.4 86.6 40.9 1.0 28.4 2.2 2.1 0.0 0.1 43.0 40.0 4.5 100.4 58.9 56.6 17.7 20.5 0.6 6.6 43.3 40.1 0.5 2.0 146.0 61.1 1.4 46.2 0.3 34.5 51.2 BCL6 "BCL5, BCL6A, LAZ3, ZBTB27, ZNF51" ENSG00000113916 "BCL6 transcription repressor" P41182 3 187721377-187745725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Immunity, Inflammatory response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 485.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 205.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "neutrophil: 269.1;non-classical monocyte: 76.4" "Group enriched" "Detected in all" 7 "granulocytes: 269.1;monocytes: 76.4" "Cell line enhanced" "Detected in many" "Daudi: 166.4;HSkMC: 113.9;U-698: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000307, HPA004899, HPA050645" Enhanced Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB000307: AB_2063451, HPA004899: AB_1078273, HPA050645: AB_2681199" "unprognostic (5.36e-2)" "unprognostic (3.29e-2)" "unprognostic (1.63e-3)" "unprognostic (2.49e-1)" "unprognostic (2.85e-1)" "unprognostic (6.34e-3)" "unprognostic (2.62e-2)" "unprognostic (3.33e-3)" "unprognostic (8.75e-2)" "unprognostic (2.04e-2)" "unprognostic (1.63e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.27e-9)" "unprognostic (5.22e-2)" "unprognostic (7.82e-2)" "unprognostic (5.67e-2)" "unprognostic (2.58e-2)" 143.0 49.4 54.3 53.9 53.4 123.7 126.9 85.9 57.9 100.0 35.0 87.1 7.5 68.1 16.4 44.6 140.7 45.6 72.1 50.9 68.7 37.0 65.3 110.5 56.0 104.1 69.4 65.6 49.2 11.3 44.8 15.3 74.2 57.5 10.3 34.2 70.3 22.2 485.9 160.7 34.4 43.0 55.9 106.3 58.4 18.6 69.0 43.2 50.4 96.6 47.7 90.6 81.5 64.1 5.1 13.8 14.4 3.2 98.1 78.0 14.9 16.5 39.2 18.4 19.4 9.4 7.6 166.4 11.5 21.0 11.7 7.7 4.4 10.6 15.3 33.8 5.1 0.2 6.7 22.5 51.5 2.1 0.9 113.9 68.8 22.7 32.9 60.1 10.2 4.2 1.6 27.6 18.2 5.7 5.5 1.3 1.4 3.0 10.3 45.4 7.0 0.8 13.6 23.2 3.1 0.2 18.8 8.1 11.0 30.2 35.3 5.9 21.2 43.7 7.1 16.6 7.5 21.2 7.2 231.6 24.2 6.0 31.7 8.8 33.0 18.9 5.5 37.3 5.4 6.6 3.4 5.0 24.6 15.3 2.1 2.3 269.1 3.9 76.4 4.0 3.1 30.7 54.3 53.4 85.9 57.9 50.9 68.7 104.1 69.4 74.2 55.9 69.0 64.1 35.7 19.2 67.4 66.0 22.7 47.3 14.7 18.8 205.5 10.9 55.3 54.6 71.4 14.3 28.9 16.5 20.9 1.4 36.0 3.5 0.0 12.2 13.3 36.2 26.7 25.0 4.8 3.2 7.6 12.5 2.7 57.3 12.2 51.4 11.4 9.4 15.0 51.2 11.9 0.0 19.6 2.3 16.2 67.5 74.4 8.6 28.9 48.1 35.6 7.5 16.8 39.1 1.0 50.8 7.8 7.9 0.3 18.8 14.2 27.9 1.2 1.5 29.5 9.7 32.9 77.0 84.9 0.4 1.2 72.4 61.5 4.1 30.0 10.3 2.8 29.7 BCL7A BCL7 ENSG00000110987 "BAF chromatin remodeling complex subunit BCL7A" Q4VC05 12 122019422-122062044 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.9;Horizontal cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.0;naive B-cell: 2.1;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 14 "B-cells: 2.1;dendritic cells: 2.8" "Cell line enhanced" "Detected in many" "Daudi: 71.9;MOLT-4: 71.4;U-698: 95.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019762 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Vesicles" "HPA019762: AB_10962489" "unprognostic (3.27e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.46e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (5.18e-1)" "unprognostic (5.13e-2)" "unprognostic (1.06e-2)" "unprognostic (3.13e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.54e-6)" "unprognostic (4.86e-2)" "unprognostic (8.56e-2)" "unprognostic (6.16e-3)" "unprognostic (1.51e-2)" 3.1 2.8 9.2 5.2 10.8 9.8 5.7 8.9 11.2 5.1 0.0 4.0 2.5 4.5 6.7 2.8 8.4 2.4 7.6 9.6 3.2 9.1 4.9 3.9 16.2 3.5 4.7 3.7 9.1 9.1 5.2 1.9 3.3 5.1 2.9 4.1 7.0 5.9 11.5 8.2 3.0 3.3 2.9 5.8 3.8 2.2 4.5 24.7 9.0 8.9 15.4 4.8 4.8 9.1 6.0 6.2 29.9 17.9 2.2 1.1 6.0 3.2 3.1 5.3 4.9 3.2 2.4 71.9 9.2 2.7 2.7 8.8 22.7 16.4 5.3 0.0 25.0 3.5 0.4 5.5 6.5 13.8 8.1 4.7 21.3 3.9 26.7 8.1 7.7 42.3 18.3 0.0 4.3 10.7 71.4 1.3 10.7 9.7 11.0 33.2 8.5 1.2 13.4 14.3 26.5 28.9 3.4 0.8 13.1 7.7 17.4 13.6 6.9 0.7 5.1 10.0 6.1 9.4 5.4 95.8 2.1 9.3 6.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.3 2.1 0.1 0.1 0.1 0.0 0.0 2.8 0.0 0.1 9.2 10.8 8.9 11.2 9.6 3.2 3.5 4.7 3.3 2.9 4.5 9.1 4.6 22.4 9.2 8.5 51.6 35.9 77.9 26.5 22.8 41.8 32.7 33.5 28.6 42.9 19.0 38.6 18.8 1.5 38.1 5.9 58.7 33.5 6.9 39.3 10.9 5.6 21.5 18.7 15.9 10.9 0.9 11.9 7.1 26.8 10.8 16.6 5.3 18.6 4.2 107.7 19.9 8.6 16.2 2.2 14.3 18.7 14.0 9.8 12.4 1.9 6.2 5.5 1.0 13.6 16.2 10.0 6.9 7.9 6.8 29.9 1.6 31.3 20.7 14.0 6.6 34.7 16.6 0.7 7.7 5.3 30.1 0.5 3.2 42.9 11.7 32.3 BCL9 ENSG00000116128 "BCL9 transcription coactivator" O00512 1 147541501-147626216 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Oligodendrocyte precursor cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "NTERA-2: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020274 Approved Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear bodies" "HPA020274: AB_2670400" "unprognostic (2.31e-1)" "unprognostic (1.52e-2)" "unprognostic (5.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.74e-4)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.29e-1)" "unprognostic (4.78e-3)" "unprognostic (3.92e-2)" "unprognostic (1.64e-3)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (1.60e-2)" 3.7 6.2 6.1 4.5 5.6 3.2 3.9 7.6 5.8 10.8 1.1 8.6 4.8 14.4 13.7 4.9 16.4 4.6 7.7 5.6 7.1 6.8 3.5 4.5 3.9 6.0 5.2 14.6 5.0 10.8 7.2 4.1 4.1 9.1 6.9 7.4 7.5 11.1 8.1 7.1 4.7 13.9 4.1 3.1 6.2 5.5 4.9 11.1 6.8 6.2 4.4 7.1 6.5 4.8 5.5 5.3 36.4 27.2 4.1 4.8 7.1 4.4 6.9 4.7 4.6 6.9 8.1 5.2 9.6 4.1 7.9 4.3 23.3 8.0 4.4 12.4 6.5 2.5 5.7 4.6 3.5 1.6 7.2 4.8 6.7 5.6 4.1 8.4 7.4 16.8 4.9 8.3 4.2 12.4 13.1 1.2 43.2 11.0 11.5 13.8 9.2 10.1 18.4 6.0 10.0 21.4 4.9 9.0 8.6 33.3 11.4 2.5 5.5 3.3 15.5 9.4 7.1 36.6 10.0 9.7 8.4 1.4 16.3 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.2 0.2 6.1 5.6 7.6 5.8 5.6 7.1 6.0 5.2 4.1 4.1 4.9 4.8 4.6 0.0 2.2 39.5 2.1 3.1 6.0 2.8 14.8 12.1 10.1 5.0 7.4 7.2 2.9 12.9 2.1 2.1 1.2 3.2 11.7 4.4 10.5 21.0 17.5 4.1 28.3 0.0 12.9 4.7 2.5 7.5 2.6 24.6 8.8 12.8 5.7 3.7 1.3 6.7 20.7 7.9 4.1 1.9 1.4 5.3 9.6 1.9 0.0 8.4 1.1 4.8 4.1 31.2 24.2 4.5 1.4 7.9 4.4 6.1 1.3 7.0 4.8 3.1 0.0 6.8 7.3 4.0 8.6 9.7 3.7 2.1 3.6 4.8 6.6 3.3 BCL9L "B9L, Bcl9-2, DLNB11" ENSG00000186174 "BCL9 like" Q86UU0 11 118893875-118925608 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049370, HPA053421" Uncertain Enhanced Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA049370: AB_2680732, HPA053421: AB_2682145" "unprognostic (1.67e-2)" "unprognostic (1.48e-2)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (2.87e-1)" "unprognostic (1.90e-1)" "unprognostic (6.61e-3)" "unprognostic (1.17e-3)" "unprognostic (1.03e-1)" "unprognostic (4.61e-2)" "unprognostic (4.66e-3)" "unprognostic (1.39e-1)" "unprognostic (2.83e-3)" "unprognostic (4.85e-3)" "unprognostic (2.24e-2)" "unprognostic (2.14e-1)" "unprognostic (2.90e-3)" 24.3 24.8 5.7 24.1 4.6 20.5 21.1 17.7 6.7 28.5 4.7 23.8 17.4 32.3 4.7 26.4 29.6 18.1 20.9 4.9 1.2 12.1 10.8 24.4 19.5 3.3 3.7 29.4 21.3 8.5 7.8 24.4 1.3 18.1 5.4 2.9 25.9 16.6 29.0 30.8 19.8 17.7 1.1 19.6 18.5 6.4 5.3 13.7 16.8 12.3 12.8 24.6 24.8 1.8 40.5 71.6 10.2 18.5 32.2 30.8 64.3 54.6 41.4 16.9 9.9 77.0 78.2 11.0 70.8 57.4 68.7 76.0 5.0 99.9 4.4 13.4 2.6 10.9 41.2 26.8 36.1 3.7 10.0 39.2 60.8 20.3 40.5 32.5 15.1 6.4 14.3 12.4 11.9 67.2 8.2 3.1 12.1 24.1 40.8 17.2 4.3 7.4 17.5 27.6 5.5 8.1 76.7 114.2 10.3 18.0 90.3 4.5 51.1 53.7 40.7 16.4 46.9 2.6 0.1 3.3 29.0 12.5 31.3 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.0 0.2 5.7 4.6 17.7 6.7 4.9 1.2 3.3 3.7 1.3 1.1 5.3 1.8 16.3 16.0 11.5 9.1 18.3 38.7 9.3 18.5 13.1 20.0 23.8 16.5 2.4 15.7 14.1 7.3 4.2 12.7 42.2 10.9 0.0 14.0 0.1 36.6 31.5 12.3 5.4 1.3 3.9 15.1 8.4 14.1 13.3 61.9 2.5 12.2 11.4 9.7 4.4 13.5 4.8 5.4 4.1 6.1 11.6 0.5 14.6 8.0 7.2 12.2 16.5 5.5 32.0 5.0 1.1 29.3 7.4 14.3 14.8 23.5 10.8 3.3 14.0 3.1 26.3 12.4 26.4 0.6 1.4 34.7 45.3 35.4 33.0 8.6 6.8 11.1 BCLAF1 "BTF, KIAA0164" ENSG00000029363 "BCL2 associated transcription factor 1" Q9NYF8 6 136256627-136289851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 135.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006484, HPA006669, HPA027770" Enhanced Enhanced "Nuclear speckles" NA NA 21000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "HPA006484: AB_2667600, HPA006669: AB_1078302, HPA027770: AB_1845484" "prognostic unfavorable (1.64e-4)" "unprognostic (1.60e-1)" "prognostic favorable (3.44e-4)" "unprognostic (1.45e-1)" "unprognostic (9.46e-3)" "unprognostic (2.29e-1)" "unprognostic (2.13e-3)" "unprognostic (1.63e-1)" "unprognostic (5.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (4.19e-3)" 24.4 22.3 14.3 26.9 17.3 135.0 32.9 23.6 18.6 21.4 19.7 29.5 18.8 23.2 24.0 24.3 21.3 14.8 16.7 15.9 19.2 21.5 27.4 24.6 28.2 11.1 12.9 24.4 25.5 33.4 18.0 21.3 12.0 21.2 28.4 34.8 21.2 20.5 27.5 21.8 21.1 28.3 14.7 24.8 27.9 21.3 16.7 35.2 30.4 24.3 32.9 23.0 19.3 19.3 82.4 70.0 162.5 136.2 50.4 42.6 82.3 153.0 94.4 100.6 106.5 100.4 54.4 172.7 92.8 117.9 112.8 78.0 183.5 101.1 125.5 95.1 114.2 213.7 96.0 110.3 58.6 362.6 131.0 58.3 49.2 142.8 88.6 37.2 90.9 77.6 193.6 82.3 107.0 97.4 145.3 40.2 120.2 55.2 72.0 130.3 203.2 76.4 76.3 155.0 137.2 94.5 150.0 71.3 60.4 60.6 66.9 71.5 125.7 79.2 116.7 95.9 151.2 69.5 134.8 227.9 47.2 113.3 94.2 32.6 27.1 42.1 32.4 33.2 32.7 36.6 29.9 28.1 42.3 32.9 37.7 34.5 57.9 49.5 35.3 24.7 25.5 24.5 14.3 17.3 23.6 18.6 15.9 19.2 11.1 12.9 12.0 14.7 16.7 19.3 165.3 205.1 178.7 68.9 174.3 68.2 118.9 99.5 104.2 129.7 86.9 71.5 88.4 65.8 131.6 57.0 210.6 111.9 173.3 86.3 33.2 96.8 12.6 157.2 173.5 117.5 118.9 134.6 80.5 65.2 99.4 138.0 128.0 169.8 156.4 130.5 74.3 60.0 74.0 102.6 82.6 106.0 93.6 92.5 88.9 13.8 122.1 121.8 69.4 56.2 136.9 91.6 118.4 63.3 93.4 77.5 81.4 109.4 197.8 128.6 83.3 42.9 147.1 139.9 111.7 259.8 130.7 102.2 129.7 121.4 71.2 128.3 174.8 154.8 101.6 123.8 BCOR "FLJ20285, KIAA1575" ENSG00000183337 "BCL6 corepressor" Q6W2J9 X 40049815-40177329 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056308, HPA073591" Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA056308: AB_2683095, HPA073591: AB_2732227" "unprognostic (2.75e-2)" "unprognostic (2.83e-1)" "unprognostic (2.45e-1)" "unprognostic (9.26e-2)" "unprognostic (1.55e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.30e-5)" "unprognostic (3.82e-3)" "unprognostic (6.86e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.91e-3)" "unprognostic (6.83e-2)" "unprognostic (9.57e-2)" "unprognostic (2.63e-1)" "unprognostic (1.55e-1)" 10.2 14.0 2.4 8.3 3.8 22.2 10.0 3.0 3.7 11.5 3.8 14.7 8.8 11.0 5.4 14.4 10.9 7.5 14.0 1.9 2.9 12.9 14.6 12.3 15.0 4.5 3.3 20.0 13.9 14.0 12.0 12.3 2.8 12.5 6.8 14.2 11.9 8.4 20.6 14.7 11.2 8.7 2.0 10.7 12.2 9.0 3.8 25.8 15.6 7.2 12.5 10.9 11.4 5.1 35.5 21.9 45.1 50.5 4.7 3.3 7.8 11.4 18.6 14.4 11.7 8.9 13.5 31.3 13.3 21.7 8.9 31.0 70.8 9.3 12.0 56.0 67.4 36.2 31.8 31.7 7.6 28.7 19.3 5.6 12.0 16.7 7.0 20.0 19.8 20.2 94.7 74.3 14.8 17.9 65.8 27.2 43.4 14.2 33.9 32.3 47.5 36.2 17.3 20.8 32.5 57.6 25.5 20.5 15.5 18.9 22.8 51.5 16.8 15.5 18.5 23.1 12.8 39.1 36.1 33.8 13.1 23.5 24.6 4.6 3.1 2.1 3.8 3.6 2.7 1.9 2.5 2.4 4.5 2.5 2.1 2.3 0.5 3.3 3.9 1.4 2.7 8.8 2.4 3.8 3.0 3.7 1.9 2.9 4.5 3.3 2.8 2.0 3.8 5.1 20.3 22.4 24.5 24.2 16.8 14.7 4.7 8.0 33.6 35.7 10.4 13.1 9.2 10.0 5.9 11.0 12.5 4.5 20.6 6.4 1.9 5.4 2.1 24.1 8.6 15.9 16.3 20.4 21.6 10.5 6.3 11.9 11.7 25.6 24.6 12.8 16.4 10.7 7.5 15.2 20.4 11.4 10.2 8.4 25.6 2.4 10.5 11.5 5.4 27.2 12.0 7.6 7.2 27.6 31.3 6.4 3.9 7.9 16.9 7.6 6.5 4.1 7.1 23.8 0.0 16.4 17.4 2.0 13.2 21.0 13.9 2.1 21.1 6.4 8.8 2.8 BCORL1 "CXorf10, FLJ11362" ENSG00000085185 "BCL6 corepressor like 1" Q5H9F3 X 129981107-130058071 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 93.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.6;HAP1: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031775, HPA031777, HPA068568" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane" "HPA031775: AB_10602332, HPA031777: AB_10671578, HPA068568: AB_2686007" "unprognostic (8.07e-2)" "unprognostic (2.78e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (2.20e-5)" "unprognostic (4.58e-1)" "unprognostic (1.68e-3)" "unprognostic (1.96e-3)" "unprognostic (5.56e-3)" "unprognostic (2.39e-1)" "unprognostic (8.02e-2)" "unprognostic (4.46e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (9.18e-2)" "unprognostic (2.60e-2)" "unprognostic (3.09e-1)" "unprognostic (1.41e-2)" 3.5 3.1 2.4 2.6 2.5 5.6 2.1 4.5 2.6 3.5 0.4 2.9 2.6 4.5 2.2 2.6 4.3 2.0 2.8 2.4 2.7 2.6 2.0 2.9 1.7 2.9 2.1 5.5 4.5 5.8 2.6 11.3 1.9 3.2 2.0 2.0 3.3 3.7 3.3 2.9 2.8 4.3 1.4 2.8 2.2 6.5 2.1 2.3 4.5 3.3 1.7 2.6 2.6 1.9 3.4 8.0 18.7 29.6 10.6 8.0 5.3 4.5 5.2 5.7 6.5 9.6 2.2 1.5 9.9 8.8 5.5 2.0 44.2 1.8 5.2 3.4 6.7 16.2 3.9 3.1 5.2 3.8 4.8 4.9 3.6 11.0 0.6 8.3 6.8 5.2 7.7 16.4 3.6 1.9 6.0 11.3 5.2 2.6 5.9 12.6 7.5 2.2 3.0 0.4 3.2 10.9 2.3 0.7 3.0 9.4 6.7 5.9 5.9 4.5 6.0 5.7 4.5 5.1 10.1 2.5 2.9 7.8 2.2 0.0 0.3 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.0 0.2 2.4 2.5 4.5 2.6 2.4 2.7 2.9 2.1 1.9 1.4 2.1 1.9 5.4 0.0 2.8 6.8 2.9 11.9 2.8 2.2 10.8 1.7 12.5 7.5 7.1 4.3 1.9 7.3 0.0 14.1 6.1 3.7 0.0 3.0 0.5 3.7 7.0 7.9 12.0 2.5 4.6 1.1 4.8 6.9 2.6 4.7 7.0 4.3 4.6 2.8 3.2 8.4 4.4 2.4 2.0 2.2 5.9 1.2 4.7 2.7 7.2 5.6 3.0 2.3 4.1 4.5 8.5 2.6 1.9 3.8 3.2 3.8 4.2 2.3 2.9 1.3 6.6 8.0 6.1 3.4 6.9 9.2 11.5 93.4 4.9 0.9 3.6 2.8 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.7" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favorable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 19.4 11.1 34.3 11.0 65.7 34.6 17.4 15.9 30.7 14.3 10.6 11.7 10.0 12.3 16.1 24.5 12.1 9.3 12.2 45.0 22.2 21.1 13.8 18.6 13.7 27.1 26.5 9.4 14.6 20.6 25.0 10.3 24.1 11.8 7.6 7.4 18.3 10.1 5.8 23.5 10.2 8.8 20.9 11.4 16.1 11.0 35.0 14.7 19.7 5.7 10.8 15.3 14.3 14.1 47.6 20.1 30.3 31.2 17.7 12.1 45.6 16.8 15.7 15.2 12.2 35.6 18.7 32.9 30.5 14.4 14.7 47.6 3.6 46.8 4.3 63.3 32.3 28.8 27.7 28.6 22.9 26.9 14.6 10.2 31.1 22.8 19.8 27.0 53.6 23.3 112.5 15.1 7.0 31.3 25.4 21.4 25.8 37.4 19.5 32.9 12.4 21.7 23.7 29.6 27.7 26.3 30.7 26.1 12.6 19.3 16.6 21.7 61.4 9.1 1.0 14.9 14.0 3.4 14.8 11.7 23.4 20.1 14.3 0.0 0.5 0.0 3.1 0.2 1.1 0.6 1.5 1.6 0.4 0.6 1.3 1.7 0.5 1.5 0.5 0.4 0.8 1.4 34.3 65.7 15.9 30.7 45.0 22.2 27.1 26.5 24.1 20.9 35.0 14.1 19.3 9.6 11.5 51.2 4.5 15.4 11.9 18.2 6.2 22.9 17.1 9.9 7.5 17.2 20.9 18.4 22.9 14.0 23.9 17.7 9.8 14.4 5.6 22.1 8.0 27.8 19.9 5.5 24.6 16.6 6.8 7.1 11.7 31.4 10.8 9.9 70.6 22.1 7.2 23.5 20.7 13.9 12.2 9.3 11.1 13.5 8.7 9.2 5.4 18.7 6.6 13.2 15.5 32.2 7.0 27.7 8.1 5.7 10.7 11.8 10.7 18.2 12.5 9.4 0.0 4.0 6.8 2.7 7.3 9.3 15.8 10.8 10.3 10.0 13.7 13.3 BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Bipolar cells: 13.8;Cardiomyocytes: 9.1;Excitatory neurons: 22.3;Smooth muscle cells: 25.8;Theca cells: 9.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 36.6;BJ hTERT+ SV40 Large T+: 28.0;BJ hTERT+ SV40 Large T+ RasG12V: 20.9;HBF TERT88: 26.5;U-138 MG: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB009564, HPA031440, HPA056104" Enhanced Supported "Nuclear speckles,Mitochondria" "Secreted to blood" NA Yes 16000000 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Mitochondria" "CAB009564: AB_2064213, HPA031440: AB_2673883, HPA056104: AB_2683038" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" 0.4 0.5 1.9 0.2 2.4 0.2 0.2 3.3 5.3 0.6 0.1 0.4 0.3 0.2 3.3 0.6 0.1 0.7 3.6 8.2 1.9 0.6 0.1 2.0 0.1 3.3 2.1 0.5 0.4 0.0 1.2 1.6 2.5 2.0 0.1 0.7 0.3 1.8 0.4 0.9 0.1 0.1 0.4 0.1 0.3 0.6 1.6 0.3 1.0 0.0 0.1 2.1 0.6 0.8 2.9 12.2 0.3 0.0 3.7 2.2 0.0 36.6 7.9 28.0 20.9 0.1 4.0 0.0 3.7 11.8 0.5 1.4 0.1 0.2 26.5 0.2 0.1 0.0 3.5 0.0 17.4 0.2 0.2 9.2 4.2 6.8 3.7 18.1 1.3 0.1 0.0 0.1 4.8 0.0 0.0 0.0 4.0 0.1 2.9 0.0 2.0 0.0 4.5 0.0 0.2 1.1 7.8 0.1 0.1 1.7 0.2 0.0 11.0 37.6 6.9 14.4 9.2 0.5 0.1 0.0 14.1 1.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.4 3.3 5.3 8.2 1.9 3.3 2.1 2.5 0.4 1.6 0.8 0.2 38.5 0.5 1.6 0.0 0.6 0.4 0.5 1.8 13.8 0.5 0.9 9.1 0.0 0.4 1.8 4.2 0.4 0.0 0.1 0.0 0.8 1.8 0.3 0.3 0.2 0.0 0.0 22.3 0.0 0.5 6.1 0.0 0.1 1.3 1.9 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.4 1.5 0.3 0.9 1.8 0.0 0.0 0.2 0.0 2.0 2.2 0.2 0.0 0.0 0.0 0.8 0.0 1.5 0.1 1.8 0.0 1.8 25.8 3.7 0.8 2.3 0.0 0.7 0.0 9.3 0.1 0.1 BHMT2 ENSG00000132840 "Betaine--homocysteine S-methyltransferase 2" Q9H2M3 5 79069767-79090069 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "kidney: 333.1;liver: 429.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Hepatocytes: 201.2;Proximal tubular cells: 408.6" "Group enriched" "Detected in many" 14 "liver cancer: 79.6;renal cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 17.5;Hep G2: 78.2;hTEC/SVTERT24-B: 46.0;U-87 MG: 18.6" "Not detected" "Not detected" HPA044573 Enhanced NA NA 1900000 "Cluster 17: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA044573: AB_10795044" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-2)" "unprognostic (3.76e-2)" "unprognostic (4.40e-2)" "unprognostic (2.90e-3)" "unprognostic (1.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.87e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-2)" "unprognostic (5.05e-2)" "unprognostic (1.49e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-3)" 31.3 16.6 5.6 3.0 6.0 0.3 15.5 4.5 5.0 8.5 14.2 15.7 1.7 12.1 37.6 7.6 7.6 7.4 13.6 4.9 7.3 333.1 429.9 3.1 1.3 5.2 7.0 7.8 1.8 0.5 12.3 0.4 6.2 12.0 2.4 1.3 2.1 14.4 10.2 2.4 6.1 13.0 4.7 0.6 9.1 3.8 6.9 0.9 18.8 4.8 1.0 18.1 3.8 4.7 0.0 0.2 0.1 0.1 8.5 6.0 2.8 7.8 17.5 4.0 7.7 0.0 0.1 0.1 0.1 9.7 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.4 0.4 78.2 6.6 0.4 0.1 7.3 0.0 46.0 0.0 7.9 0.0 0.0 0.4 0.4 1.1 0.0 0.1 0.3 0.1 0.0 0.2 0.1 0.5 0.1 0.0 0.2 2.2 0.1 0.5 0.0 0.1 0.5 0.1 0.2 0.0 0.3 0.1 0.3 0.1 0.1 0.1 0.3 18.6 0.4 0.1 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.3 0.0 0.1 0.0 0.0 5.6 6.0 4.5 5.0 4.9 7.3 5.2 7.0 6.2 4.7 6.9 4.7 1.4 6.4 0.5 6.2 1.2 0.8 0.4 0.1 0.0 1.5 0.2 0.1 4.4 1.5 0.0 46.0 2.1 0.2 0.0 0.0 95.9 0.1 0.5 0.4 11.7 2.9 1.2 2.7 4.1 0.0 0.4 17.3 0.0 0.4 0.0 4.5 2.5 201.2 0.3 0.0 0.6 0.1 0.0 4.4 1.2 1.3 27.4 2.5 0.0 11.2 0.3 4.2 0.0 2.0 0.6 0.0 0.0 37.2 0.1 0.4 0.0 408.6 0.1 1.2 6.6 6.2 3.1 0.4 0.5 0.1 1.0 0.3 2.2 30.0 0.0 1.0 BIRC2 "API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48" ENSG00000110330 "Baculoviral IAP repeat containing 2" Q13490 11 102347211-102378670 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005513, CAB020661" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli fibrillar center, Cytosol" Nucleoplasm "CAB020661: , HPA005513: AB_1846746" "unprognostic (1.36e-1)" "unprognostic (3.29e-1)" "unprognostic (9.52e-3)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (7.02e-2)" "unprognostic (2.72e-2)" "unprognostic (1.04e-2)" "unprognostic (1.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.05e-2)" "unprognostic (3.02e-2)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (5.00e-2)" "unprognostic (1.64e-2)" 23.2 27.6 18.4 25.8 19.6 36.4 28.2 20.0 23.4 27.5 22.5 27.2 23.6 25.7 30.2 18.1 19.7 24.8 23.6 17.9 19.9 28.8 44.3 22.6 34.5 19.7 19.4 21.8 33.7 20.4 18.8 29.4 19.8 21.4 26.0 22.2 21.1 16.1 29.7 18.2 25.2 21.6 20.1 26.7 23.5 24.6 18.8 50.6 22.2 32.9 27.1 30.4 20.4 24.9 34.0 24.7 37.3 29.3 46.1 63.3 23.9 128.3 48.8 71.9 43.4 30.9 81.7 37.1 123.5 59.2 40.3 36.7 24.5 33.8 85.7 50.0 12.6 37.2 17.6 37.8 46.9 22.9 23.0 40.8 64.4 41.2 52.3 66.2 50.1 22.2 34.4 0.2 131.0 10.9 24.3 20.1 18.1 40.1 23.7 11.9 48.4 24.9 55.4 38.5 15.5 20.3 44.7 26.9 40.7 56.7 42.5 27.3 82.7 150.7 34.4 46.2 84.2 14.9 21.9 25.0 32.6 28.2 112.5 97.2 43.3 104.4 22.9 42.2 18.9 15.7 21.5 21.3 33.8 15.1 27.4 27.7 67.6 34.3 46.7 20.4 33.2 27.5 18.4 19.6 20.0 23.4 17.9 19.9 19.7 19.4 19.8 20.1 18.8 24.9 61.8 41.7 41.1 17.0 52.6 67.2 109.2 53.6 39.9 24.4 52.3 52.8 58.6 67.2 49.5 64.4 29.2 38.4 77.9 85.7 43.0 49.8 20.8 63.2 54.0 51.0 48.5 80.0 22.4 73.7 27.8 55.9 28.5 85.7 62.7 43.7 59.3 182.1 41.5 20.2 21.7 54.3 46.8 84.3 71.5 11.2 36.4 71.1 51.6 26.2 81.2 34.3 55.6 21.6 33.1 54.5 71.1 29.0 49.2 75.0 82.1 110.1 56.6 31.0 26.3 45.7 48.9 44.7 42.4 28.4 62.8 35.2 57.1 36.4 44.2 82.5 BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.0;lymphoid tissue: 141.5" "Cell type enhanced" "Detected in many" "granulocytes: 554.8;Langerhans cells: 1400.9;monocytes: 1117.0;Proximal enterocytes: 817.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 209.0;naive B-cell: 159.9" "Group enriched" "Detected in all" 13 "B-cells: 209.0;T-cells: 83.6" "Cell line enhanced" "Detected in many" "CAPAN-2: 146.5;Daudi: 140.7;EFO-21: 74.3;HDLM-2: 140.1;hTERT-HME1: 140.2;U-266/70: 89.2;U-266/84: 85.8" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favorable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavorable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" 9.0 14.7 2.7 104.8 2.9 26.3 18.4 1.6 3.4 19.1 3.4 24.9 26.6 10.5 3.7 16.0 8.5 51.0 7.7 2.8 3.5 12.6 26.3 24.6 141.5 2.6 2.7 6.6 12.0 4.3 3.6 5.3 2.3 10.6 24.7 0.6 12.7 11.4 2.7 8.1 89.0 10.7 2.5 73.2 54.3 8.2 2.7 59.2 3.9 4.3 134.4 46.9 4.8 3.6 26.4 24.5 0.2 0.4 0.7 3.9 2.4 2.5 17.5 3.3 3.7 4.6 146.5 140.7 74.3 1.4 22.8 13.0 0.1 4.6 7.8 140.1 0.3 0.5 7.3 1.4 30.7 2.4 3.7 3.5 18.1 8.4 140.2 4.9 0.4 10.2 0.5 0.0 3.0 0.1 8.3 1.3 0.3 14.2 1.0 0.1 0.8 6.8 34.3 12.9 0.1 0.3 2.1 2.1 1.8 0.5 6.4 1.8 7.5 25.6 3.4 1.4 28.3 89.2 85.8 48.8 4.0 7.4 3.0 8.6 3.9 2.2 5.8 10.1 9.8 209.0 41.7 14.1 3.6 159.9 28.4 8.3 2.6 9.9 11.0 1.7 83.6 11.9 2.7 2.9 1.6 3.4 2.8 3.5 2.6 2.7 2.3 2.5 2.7 3.6 41.2 144.2 70.8 0.0 420.1 101.2 324.9 267.2 51.2 0.3 26.6 22.9 12.5 134.4 146.9 40.5 0.0 2.0 71.2 142.4 7.9 230.3 1.8 231.3 16.8 101.4 15.0 23.6 1.1 179.7 0.5 63.4 184.5 289.4 554.8 1.8 6.4 4.4 11.7 0.0 3.2 38.0 75.3 25.4 1400.9 2.1 5.0 170.0 192.1 2.8 1117.0 0.5 14.4 0.0 0.4 207.4 281.1 2.2 288.4 455.1 817.3 19.5 88.1 0.0 0.0 60.8 90.9 0.7 0.5 31.8 84.5 0.5 278.0 0.7 49.4 193.3 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 272.0;Inhibitory neurons: 291.3;Oligodendrocytes: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: AB_2686710" "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 4.6 4.7 3.1 6.7 9.7 11.3 8.9 13.9 5.7 7.7 6.3 7.6 5.0 6.8 5.2 5.3 6.2 5.8 4.9 4.6 3.7 7.6 8.9 5.4 9.6 6.4 5.5 12.0 14.7 10.9 2.9 6.9 7.3 6.2 7.5 15.5 5.5 5.9 6.1 6.7 5.4 6.1 4.4 8.5 7.1 6.8 5.6 14.7 11.4 8.8 9.7 7.2 3.1 16.3 21.7 17.8 16.1 7.9 14.9 19.1 11.3 10.8 14.1 11.0 11.3 14.2 5.7 23.6 7.3 19.7 13.2 10.1 22.9 15.1 13.9 18.8 10.5 31.2 11.3 10.7 7.9 32.4 11.9 12.4 6.9 18.0 16.2 10.1 17.7 5.4 25.6 10.0 11.9 9.3 15.5 7.5 11.7 9.2 10.5 14.6 26.6 8.2 9.2 23.4 11.7 18.4 18.6 10.8 8.2 12.5 6.4 11.5 28.7 13.0 13.3 9.1 15.3 13.9 20.0 30.6 10.1 15.1 8.7 9.7 0.9 0.6 1.3 0.7 1.8 0.8 1.0 1.2 0.7 1.8 1.1 1.4 1.5 1.6 1.5 1.6 1.0 0.5 3.1 9.7 13.9 5.7 4.6 3.7 6.4 5.5 7.3 4.4 5.6 16.3 53.9 32.1 30.5 239.3 74.8 46.0 28.6 34.7 41.5 60.8 40.0 23.4 45.8 38.6 42.7 36.8 191.8 35.0 93.4 70.1 1.9 26.9 45.9 39.3 58.0 49.8 32.5 34.3 272.0 31.2 22.0 39.7 68.3 63.1 29.9 52.1 45.7 47.5 29.8 69.0 291.3 43.3 26.4 54.7 60.0 17.6 45.4 59.1 23.2 202.4 67.2 34.9 64.9 231.8 361.3 34.3 30.3 59.0 70.9 46.4 48.5 22.6 30.6 88.2 39.5 56.0 49.1 53.7 46.2 49.7 54.8 38.0 72.4 52.8 45.3 44.0 BIVM-ERCC5 ENSG00000270181 "BIVM-ERCC5 readthrough" 13 102799110-102875994 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.3;Club cells: 2.5;Excitatory neurons: 6.4;granulocytes: 2.5;Inhibitory neurons: 7.5;Oligodendrocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 1.3;HMC-1: 1.3;hTERT-RPE1: 1.3;RPTEC TERT1: 2.5;SK-MEL-30: 1.4" "HPA045845, HPA050126, HPA050374" Uncertain Approved Nucleoplasm NA NA "Cluster 72: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA045845: AB_2679471, HPA050126: AB_2681027, HPA050374: AB_2681106" "unprognostic (6.01e-2)" 10.2 9.5 0.2 0.1 0.0 0.0 9.5 0.4 0.2 10.1 0.0 9.9 0.0 9.7 0.0 8.7 8.6 0.3 8.6 0.1 0.0 9.7 12.4 9.1 0.0 0.0 0.2 10.5 11.7 0.1 9.3 0.0 0.0 8.8 0.2 0.2 9.3 0.0 12.5 9.7 9.9 0.1 0.0 9.4 9.4 3.2 0.1 0.0 9.9 0.0 0.0 9.2 9.2 0.3 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.4 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.2 1.3 0.9 0.6 0.7 0.0 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.3 0.5 1.3 0.3 0.5 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.5 0.5 0.0 0.0 1.4 0.0 0.1 0.8 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 2.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.4 0.0 0.0 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564599 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 39.1;lymphoid tissue: 46.7" "Cell type enriched" "Detected in some" 11 "B-cells: 116.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 183.4;naive B-cell: 131.5" "Lineage enriched" "Detected in many" 5 "B-cells: 183.4" "Cell line enhanced" "Detected in some" "Daudi: 106.6;REH: 29.9;RPMI-8226: 38.5;U-698: 48.6;U-87 MG: 22.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB005093, HPA069571" Approved Uncertain Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "CAB005093: AB_2274756, HPA069571: AB_2732137" "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.1 0.0 9.1 0.0 2.6 0.2 0.0 0.0 0.0 0.0 2.6 0.5 0.1 0.0 1.2 0.2 0.5 0.1 0.0 0.0 1.2 0.7 0.8 29.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.0 0.7 0.0 0.3 0.0 39.1 0.1 0.0 46.7 2.1 0.1 0.0 2.5 1.2 0.0 27.9 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 29.9 0.0 38.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 5.4 10.2 48.6 22.7 0.0 0.0 0.2 0.1 0.2 2.0 0.0 37.9 183.4 1.4 4.6 0.1 131.5 0.9 0.4 0.7 0.1 0.1 17.5 1.8 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 116.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.1 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 4.0 0.1 0.1 0.0 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 0.3 0.2 0.9 3.6 1.1 5.7 0.5 2.3 0.9 0.1 0.3 1.4 1.0 0.4 0.4 0.6 0.3 0.3 0.3 0.8 1.1 0.1 0.1 0.4 6.4 1.2 1.4 0.1 0.2 0.0 0.6 1.2 1.1 0.1 1.7 2.4 7.8 0.0 0.5 0.4 1.6 0.4 1.0 1.6 1.1 2.2 0.9 7.9 0.3 0.1 6.2 1.0 0.2 1.0 13.0 14.4 20.4 12.6 0.1 0.9 14.6 9.4 3.2 11.1 13.4 11.7 10.1 35.1 5.9 2.6 14.1 20.4 25.7 7.1 15.1 19.1 20.5 36.4 14.8 3.9 0.0 33.7 17.3 0.3 0.1 10.6 4.7 1.3 7.9 16.9 32.7 9.9 11.0 7.4 28.3 14.5 22.2 24.9 4.2 25.4 39.1 14.7 2.3 18.9 14.6 14.7 8.5 11.5 4.8 18.1 7.2 23.4 3.7 8.6 13.6 9.6 21.0 6.4 30.4 39.5 5.6 25.8 15.7 1.7 0.6 2.6 1.6 0.8 2.6 4.6 1.4 2.1 0.7 2.3 1.0 1.1 0.7 3.1 1.0 0.7 3.2 0.9 0.9 1.1 2.3 0.9 0.8 1.1 1.2 1.4 1.1 1.0 0.9 1.0 0.9 3.2 8.9 1.0 12.9 0.3 0.5 0.5 0.6 3.6 1.3 1.0 7.9 0.0 4.2 0.0 2.1 5.5 6.9 2.2 1.9 1.0 2.7 1.3 1.3 2.0 0.0 18.3 0.7 0.7 6.8 1.8 3.6 1.7 13.3 8.1 2.2 0.6 5.7 0.0 8.6 1.3 0.0 7.7 1.3 1.6 0.0 7.7 0.0 7.5 2.7 1.7 10.3 58.3 2.6 1.2 0.3 0.4 20.6 0.7 0.2 0.0 5.4 7.1 0.0 0.9 1.7 17.1 12.9 2.2 0.6 1.0 10.2 0.7 4.0 0.4 BLMH BH ENSG00000108578 "Bleomycin hydrolase" Q13867 17 30248203-30292056 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 130.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039548, HPA064307" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 42000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA039548: AB_10805479, HPA064307: AB_2685241" "unprognostic (6.85e-2)" "unprognostic (2.79e-1)" "unprognostic (1.48e-1)" "unprognostic (2.46e-1)" "unprognostic (1.76e-1)" "unprognostic (2.54e-2)" "unprognostic (3.91e-3)" "unprognostic (2.07e-1)" "unprognostic (2.05e-3)" "unprognostic (6.69e-3)" "unprognostic (1.95e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.22e-3)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" 20.6 13.5 13.4 18.2 15.0 18.1 20.4 15.9 17.6 19.1 14.5 18.8 12.4 21.2 21.1 28.3 14.7 18.4 15.6 13.5 15.2 22.0 14.0 16.0 26.0 15.6 14.1 13.9 26.8 21.7 9.7 27.4 15.4 14.4 15.4 14.7 15.6 14.4 28.8 130.3 18.3 22.4 14.7 20.6 16.2 15.9 14.2 36.3 16.5 19.0 26.9 17.9 21.5 16.2 40.3 62.9 61.5 41.6 40.6 43.8 27.8 36.5 24.0 59.1 50.8 93.2 11.9 119.5 63.3 31.1 26.1 27.1 135.5 52.8 50.1 31.5 101.4 73.5 54.6 80.0 58.3 136.1 43.2 50.5 3.5 46.5 26.5 47.1 87.2 98.2 157.9 47.6 24.6 31.0 168.1 98.6 57.2 0.0 29.2 143.0 154.5 78.9 46.8 35.6 135.1 48.4 32.6 63.2 42.2 106.6 42.9 68.5 54.5 35.0 69.2 16.0 66.0 55.8 124.1 159.3 26.7 0.2 47.6 0.0 8.8 1.5 15.3 6.2 25.3 6.5 18.2 20.2 10.1 7.3 16.4 17.8 1.2 16.3 3.3 10.1 20.0 9.9 13.4 15.0 15.9 17.6 13.5 15.2 15.6 14.1 15.4 14.7 14.2 16.2 21.0 3.2 12.6 13.4 8.8 15.9 16.7 10.6 19.4 20.2 10.3 6.6 17.8 12.8 4.0 11.0 12.5 49.6 15.6 7.6 7.9 17.4 8.4 7.4 28.2 24.0 18.0 22.5 19.0 14.2 38.0 18.3 11.2 7.0 43.8 30.5 25.7 6.9 25.0 13.5 20.9 8.4 6.1 18.9 7.1 6.6 16.1 13.0 10.6 18.7 12.2 9.9 22.6 29.1 22.6 7.2 9.6 24.8 20.0 13.0 11.5 20.0 5.5 15.7 6.6 12.9 19.7 14.9 29.1 24.0 12.6 27.5 20.9 34.8 11.5 7.6 BMI1 "PCGF4, RNF51" ENSG00000168283 "BMI1 proto-oncogene, polycomb ring finger" P35226 10 22321099-22331484 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 134.0;Late spermatids: 165.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 508.3;U-937: 583.9" "CAB011120, HPA030471, HPA030472" Supported Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Nucleoli, Cytosol" "CAB011120: , HPA030471: AB_2673491, HPA030472: AB_10601090" "unprognostic (5.44e-1)" "unprognostic (2.98e-1)" "unprognostic (4.24e-2)" "unprognostic (4.37e-2)" "unprognostic (2.76e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (2.60e-8)" "unprognostic (9.43e-2)" "unprognostic (7.95e-2)" "unprognostic (7.84e-2)" "unprognostic (8.23e-2)" "unprognostic (1.56e-1)" "unprognostic (7.44e-2)" "unprognostic (9.73e-2)" "unprognostic (8.56e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-2)" 29.0 31.1 26.6 25.1 35.1 21.9 36.0 29.9 42.4 27.6 28.2 26.2 19.7 30.7 29.7 21.9 22.6 23.9 20.5 25.0 27.8 26.0 35.6 23.4 27.7 29.5 30.1 21.7 25.7 56.9 25.0 28.7 31.6 33.7 21.5 40.4 19.9 26.1 44.4 14.4 20.8 36.2 29.9 36.2 22.5 35.3 28.1 24.9 23.9 35.5 27.0 23.8 14.8 45.4 74.9 36.1 41.2 12.7 68.9 54.6 40.5 49.7 22.2 37.3 43.5 37.6 93.4 38.1 32.8 45.6 42.2 26.1 59.1 35.0 45.4 508.3 72.8 104.7 28.7 42.9 41.1 39.8 55.7 35.5 58.8 41.2 45.3 47.0 26.2 62.1 105.4 63.3 48.6 30.2 106.9 11.4 9.3 36.3 83.4 79.6 57.1 37.3 35.3 25.2 33.8 66.0 32.7 42.5 57.3 17.8 38.5 153.8 56.4 41.4 122.6 99.6 67.6 76.1 110.8 83.1 59.5 583.9 27.4 15.1 1.3 2.5 5.2 3.0 7.0 4.4 5.3 5.0 0.9 2.2 4.4 4.3 0.6 5.2 2.1 1.6 4.1 2.0 26.6 35.1 29.9 42.4 25.0 27.8 29.5 30.1 31.6 29.9 28.1 45.4 18.9 25.6 24.0 0.0 23.1 15.9 20.5 12.4 22.8 20.9 24.4 20.3 19.0 22.8 19.8 12.9 8.4 12.7 14.2 5.6 13.7 16.3 134.0 12.1 25.3 24.0 13.2 19.1 0.0 18.2 22.2 19.8 7.7 9.8 12.0 12.6 28.5 30.7 9.9 30.3 0.0 9.9 14.2 19.7 25.6 165.1 36.1 13.8 37.4 0.0 17.5 13.9 15.5 0.0 0.0 22.9 7.3 36.5 33.9 29.1 4.6 13.0 16.9 15.2 19.7 26.5 28.6 19.8 22.2 11.2 14.6 6.7 22.4 17.0 10.3 20.4 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal keratinocytes: 167.1;Distal enterocytes: 125.6;Suprabasal keratinocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 31.6;HeLa: 19.6;hTERT-HME1: 17.8;RT4: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" NA NA 24400 21000 "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" 18.6 1.6 1.2 4.0 1.5 1.6 6.0 1.3 1.6 5.2 0.9 15.1 6.6 5.2 0.6 5.5 3.8 16.1 4.0 1.8 1.4 3.9 5.8 18.8 1.9 1.9 2.2 2.8 9.2 3.2 2.3 11.5 2.1 1.9 13.6 1.3 2.1 1.2 2.2 10.6 9.7 2.6 1.5 12.4 20.7 0.5 2.1 0.4 18.9 2.7 1.8 17.2 6.4 2.2 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.8 3.4 0.0 0.0 31.6 0.1 0.0 0.5 1.1 0.0 10.5 6.2 2.7 0.0 0.0 5.5 0.0 19.6 0.1 1.5 0.0 0.8 0.2 9.2 0.0 17.8 4.0 6.3 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.8 3.7 0.8 6.2 0.1 0.4 2.3 25.0 1.1 1.6 7.3 0.0 0.0 5.5 0.0 6.5 1.5 1.8 2.7 0.0 0.9 0.3 0.9 0.0 3.0 1.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 1.5 1.3 1.6 1.8 1.4 1.9 2.2 2.1 1.5 2.1 2.2 9.4 80.1 155.9 0.3 1.1 167.1 45.1 11.0 70.0 0.4 1.4 2.2 4.7 42.9 10.5 1.8 0.0 0.1 3.8 125.6 0.0 23.3 0.3 1.7 34.8 24.1 11.3 0.0 1.1 9.8 0.2 20.2 33.6 3.0 8.8 1.9 41.4 3.4 3.6 0.0 3.5 23.8 0.0 2.9 16.8 0.2 5.9 2.9 8.8 2.8 0.6 6.2 0.0 8.5 1.4 33.5 60.3 0.0 1.3 47.5 28.3 2.1 0.8 0.2 19.7 36.5 48.8 0.0 0.3 43.1 119.3 0.1 2.1 4.3 48.2 43.3 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BMPR1A "ACVRLK3, ALK3, CD292" ENSG00000107779 "Bone morphogenetic protein receptor type 1A" P36894 10 86756601-86932825 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Inhibitory neurons: 79.9;Oligodendrocyte precursor cells: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019398 Approved Approved Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "CAB019398: " "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (3.34e-1)" "unprognostic (9.61e-2)" "unprognostic (1.05e-3)" "unprognostic (9.34e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (3.64e-1)" "unprognostic (2.38e-2)" "unprognostic (1.53e-1)" "unprognostic (9.24e-2)" "unprognostic (9.42e-2)" "unprognostic (4.32e-2)" "unprognostic (1.80e-1)" "unprognostic (1.47e-1)" "unprognostic (1.01e-2)" "unprognostic (1.07e-1)" 9.1 6.4 4.3 4.5 5.2 0.0 10.3 5.4 5.5 8.1 4.9 9.9 5.4 12.9 11.9 7.8 7.4 9.6 7.8 4.7 6.1 7.0 4.3 7.3 2.9 6.8 5.8 11.6 5.8 9.9 2.6 6.5 6.3 12.5 8.2 4.8 12.1 13.0 7.9 9.3 8.6 12.5 6.2 2.9 7.3 5.2 4.6 2.9 19.1 4.8 3.0 7.9 4.1 6.5 14.6 7.8 27.6 26.8 15.0 10.6 5.5 14.5 18.3 9.4 11.3 11.0 13.1 4.7 6.1 19.2 5.9 15.0 15.8 14.3 14.1 5.5 8.2 5.9 6.9 19.0 10.2 7.4 37.7 10.7 8.5 11.2 9.5 13.9 0.0 8.1 7.6 2.7 12.3 7.0 6.7 7.8 17.6 5.2 4.2 0.0 12.3 0.1 18.9 12.1 3.7 12.8 17.8 8.4 12.6 34.1 15.0 4.1 6.2 7.0 9.8 12.7 13.3 0.3 12.3 5.3 6.5 5.6 6.0 0.3 0.0 0.0 0.3 0.0 0.2 0.3 0.2 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.0 4.3 5.2 5.4 5.5 4.7 6.1 6.8 5.8 6.3 6.2 4.6 6.5 3.5 35.3 22.4 142.7 3.5 12.1 7.1 9.9 17.6 7.5 10.2 10.2 22.6 18.6 10.5 11.0 20.9 14.1 2.3 10.7 1.9 10.6 0.7 10.7 19.7 4.5 18.0 0.0 63.8 9.5 1.0 20.6 19.4 13.9 15.2 22.9 9.3 7.2 3.4 11.8 79.9 13.9 8.2 4.8 6.1 4.1 33.5 2.3 8.8 34.7 0.8 12.9 2.1 122.2 64.3 8.9 4.9 31.2 3.2 13.7 10.6 5.5 16.5 20.4 6.6 20.3 19.2 2.1 6.6 11.5 9.8 5.1 4.3 11.9 11.1 6.7 BNIP3 Nip3 ENSG00000176171 "BCL2 interacting protein 3" Q12983 10 131966455-131982013 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 361.5;skeletal muscle: 214.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 544.1;Hepatocytes: 437.4;Proximal tubular cells: 714.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 390.1;hTERT-RPE1: 286.7;U-87 MG: 347.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003015, CAB011676" Supported NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB011676: , HPA003015: AB_1078290" "unprognostic (1.01e-3)" "unprognostic (1.42e-3)" "unprognostic (1.46e-1)" "unprognostic (8.04e-2)" "unprognostic (1.58e-2)" "unprognostic (1.62e-3)" "unprognostic (6.57e-3)" "unprognostic (1.12e-1)" "unprognostic (2.71e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (4.55e-4)" "unprognostic (2.37e-3)" "unprognostic (1.04e-1)" "unprognostic (3.29e-2)" "unprognostic (2.98e-1)" 49.2 35.0 52.3 8.1 54.9 5.9 35.7 63.6 63.0 30.1 38.1 25.9 7.7 17.4 23.8 30.0 20.5 16.8 92.8 71.2 55.8 63.9 126.4 25.9 10.0 61.5 67.9 82.2 361.5 20.3 36.7 30.0 67.4 40.6 4.8 81.4 46.9 12.8 214.4 36.3 14.9 12.1 55.5 13.7 27.9 15.7 65.8 10.0 23.2 91.4 7.9 28.2 39.4 62.3 390.1 30.7 21.6 60.9 56.7 59.5 110.9 92.7 85.3 68.3 193.2 6.4 8.4 0.7 146.5 53.6 79.5 23.3 46.2 131.4 254.7 20.7 34.9 13.8 19.2 90.1 75.4 17.9 10.6 41.4 32.7 66.6 66.8 286.7 48.1 23.6 36.0 1.4 112.9 31.0 9.2 99.3 18.5 2.7 91.1 21.8 11.0 33.3 75.1 6.4 28.5 66.3 18.9 38.7 54.3 91.1 23.7 24.7 55.4 96.0 32.3 36.4 74.4 63.5 58.1 54.0 347.4 0.9 16.8 4.2 6.3 9.8 16.6 4.2 17.7 11.4 23.4 17.7 5.6 11.6 39.1 26.3 1.5 4.3 6.2 4.3 25.4 16.5 52.3 54.9 63.6 63.0 71.2 55.8 61.5 67.9 67.4 55.5 65.8 62.3 49.3 48.1 56.5 34.3 22.5 29.8 98.3 101.0 34.7 98.2 75.8 63.1 159.2 137.2 43.6 84.6 39.6 173.8 24.7 2.6 301.3 185.1 110.3 84.7 64.4 53.6 81.0 21.5 39.6 87.9 544.1 64.6 27.5 98.1 0.0 107.4 61.4 437.4 79.1 333.1 30.0 10.3 59.0 28.4 20.4 112.1 70.2 28.2 33.8 7.5 28.1 169.2 27.8 16.1 22.8 133.8 9.5 103.4 37.5 140.5 63.5 714.8 72.7 64.6 39.5 53.1 60.0 35.3 100.2 6.5 13.1 247.4 38.4 47.3 5.3 48.9 BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" 130.6 53.4 42.7 37.2 60.4 192.6 77.9 55.6 62.0 63.9 38.9 39.6 22.2 52.8 66.3 48.3 50.5 54.7 63.2 50.0 49.6 79.4 45.4 62.9 39.4 60.7 54.0 119.7 20.1 55.1 25.4 104.5 58.4 44.4 28.2 146.5 44.1 64.4 38.9 71.5 28.4 51.3 46.6 40.7 28.9 68.6 48.8 39.9 41.9 31.7 52.1 48.9 49.5 80.8 90.6 33.8 79.1 53.9 214.5 134.0 66.8 89.0 259.9 81.9 179.6 15.3 42.7 27.7 82.5 169.0 113.4 44.8 39.6 114.5 270.0 17.8 21.8 114.9 32.0 26.9 119.3 10.3 191.1 162.5 89.2 92.9 55.3 269.2 106.2 66.9 52.6 65.0 173.7 39.1 72.7 38.5 26.2 56.7 36.6 38.4 99.9 55.6 85.3 58.3 83.9 74.4 43.2 8.8 70.0 85.9 43.7 21.7 140.4 152.2 64.6 96.2 20.5 93.2 46.0 36.8 232.6 20.6 35.1 334.9 298.3 182.9 39.5 154.8 34.9 68.4 58.4 43.3 166.9 78.0 89.3 65.5 369.0 47.6 104.1 38.0 86.1 239.3 42.7 60.4 55.6 62.0 50.0 49.6 60.7 54.0 58.4 46.6 48.8 80.8 118.3 86.6 157.4 28.7 72.2 98.8 56.0 231.7 82.6 142.5 90.6 85.3 34.0 50.1 126.4 103.0 33.3 33.2 55.6 32.7 49.0 115.4 194.1 173.5 140.8 101.2 120.6 913.9 50.6 39.1 166.5 179.9 38.7 341.2 120.9 96.5 167.0 32.2 132.1 82.4 39.4 46.8 118.0 221.3 300.4 206.7 320.3 233.6 106.7 30.0 165.0 406.4 32.0 29.1 75.8 154.1 39.8 347.5 64.6 83.6 44.0 306.4 107.6 64.0 144.7 59.1 183.9 154.4 110.7 65.4 126.6 162.5 67.0 117.6 27.6 79.3 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924929 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 252.3;Inhibitory neurons: 242.4;Oligodendrocyte precursor cells: 206.1;Oligodendrocytes: 202.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336" "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 8.8 5.8 6.3 5.6 7.7 15.9 8.8 12.5 8.7 8.2 5.4 8.6 4.7 8.3 8.3 7.5 8.0 5.8 7.6 8.3 6.7 7.6 6.6 9.9 6.9 4.0 3.6 9.8 8.3 11.5 9.0 7.2 4.6 8.2 5.4 17.0 7.2 5.9 8.6 10.4 6.9 6.0 3.1 6.7 7.8 13.7 5.2 8.7 10.2 8.4 6.4 9.9 8.5 6.7 6.3 5.2 7.7 9.4 9.1 11.8 12.3 6.8 7.5 5.4 7.6 5.7 6.7 10.8 5.0 7.3 8.4 3.4 6.8 5.5 10.0 9.8 5.4 7.1 5.1 5.2 7.6 11.7 6.8 7.9 6.1 6.0 12.0 8.2 6.6 7.7 11.3 19.1 9.8 3.3 15.6 12.0 6.9 6.2 3.1 10.1 6.5 8.9 5.3 11.9 8.9 7.3 7.9 4.9 7.3 7.5 4.5 7.8 9.7 5.9 4.3 12.9 5.5 21.6 12.9 16.7 9.7 11.3 6.6 1.9 1.0 4.1 1.5 0.9 1.0 1.3 1.5 1.2 0.8 1.1 2.6 1.3 2.0 3.5 1.3 1.0 1.5 0.6 6.3 7.7 12.5 8.7 8.3 6.7 4.0 3.6 4.6 3.1 5.2 6.7 43.4 22.4 45.7 151.1 58.4 21.5 24.6 6.0 23.3 29.7 31.2 21.2 19.8 10.0 18.7 25.8 35.5 15.7 73.5 8.8 7.9 14.3 68.6 50.6 37.4 23.4 19.2 14.9 252.3 9.8 12.9 22.0 21.9 69.2 24.7 45.5 9.3 9.6 9.4 25.2 242.4 9.8 8.2 13.6 37.1 36.5 16.4 30.1 16.0 126.5 14.6 11.3 15.5 206.1 202.6 15.4 8.1 10.1 48.7 23.8 8.0 13.4 20.0 33.0 6.6 24.1 24.7 43.8 26.0 14.5 24.0 75.5 41.4 30.9 8.7 33.4 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BRD3 "KIAA0043, ORFX, RING3L" ENSG00000169925 "Bromodomain containing 3" Q15059 9 134030305-134068535 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 178.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051830 Approved Approved "Nuclear bodies" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "HPA051830: AB_2681627" "unprognostic (3.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-1)" "unprognostic (6.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.98e-2)" "unprognostic (3.48e-2)" "unprognostic (1.11e-2)" "unprognostic (6.75e-2)" "unprognostic (2.79e-1)" "unprognostic (1.98e-1)" "prognostic favorable (2.71e-7)" "unprognostic (1.00e-1)" "unprognostic (4.71e-2)" "unprognostic (2.57e-2)" "unprognostic (1.42e-1)" 10.6 10.3 14.2 7.3 14.7 8.2 10.2 13.0 13.6 12.9 6.4 16.1 7.9 14.6 9.4 8.6 12.5 6.9 9.5 11.6 14.6 7.8 11.0 9.2 7.5 13.9 12.6 11.6 10.7 10.1 9.2 9.0 11.7 11.8 5.6 10.6 9.6 11.6 19.3 12.6 9.6 9.0 10.4 12.4 9.9 13.0 13.5 13.4 11.8 11.5 5.8 11.8 10.3 15.9 8.5 25.3 31.4 24.6 17.1 13.8 28.7 8.4 9.5 9.2 9.3 21.2 13.7 3.2 8.7 7.7 10.4 28.7 29.4 11.7 7.2 20.1 16.5 18.2 29.1 24.1 15.3 24.1 15.7 14.8 14.1 10.6 12.0 14.9 15.2 30.0 16.7 9.3 9.5 28.4 44.9 32.2 42.0 21.9 19.2 32.8 45.3 16.1 13.1 8.9 45.8 42.3 37.7 14.1 10.1 18.7 20.3 39.6 19.5 22.3 12.3 14.6 7.6 5.0 5.6 3.0 11.2 16.4 15.1 6.6 12.9 15.8 11.4 10.1 9.6 6.9 9.1 10.2 12.9 6.7 8.6 9.1 15.0 16.3 8.6 17.1 4.6 9.4 14.2 14.7 13.0 13.6 11.6 14.6 13.9 12.6 11.7 10.4 13.5 15.9 27.6 32.1 21.9 13.1 18.3 32.4 21.2 19.8 42.1 60.9 32.8 24.3 24.3 28.6 25.7 23.9 37.5 26.0 31.8 22.6 19.6 42.7 49.2 22.9 37.9 32.1 54.0 70.1 13.4 24.4 20.5 32.4 21.9 25.3 15.9 53.2 35.7 34.0 18.7 57.2 16.8 26.6 14.2 27.9 22.8 20.7 57.2 33.6 23.2 10.3 33.6 45.6 30.9 12.5 19.3 27.7 21.4 67.4 9.1 51.0 19.2 15.7 20.1 58.0 59.2 55.8 40.0 20.7 53.1 31.9 35.7 32.7 26.4 178.7 30.8 22.3 BRD4 "CAP, HUNK1, HUNKI, MCAP" ENSG00000141867 "Bromodomain containing 4" O60885 19 15235519-15332545 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015055, HPA061646, CAB068177, CAB068178" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "CAB068177: AB_2665685, CAB068178: AB_2665686, HPA015055: AB_1845435, HPA061646: AB_2684575" "unprognostic (2.83e-3)" "unprognostic (2.39e-2)" "unprognostic (6.37e-3)" "unprognostic (3.38e-2)" "unprognostic (2.15e-1)" "unprognostic (9.53e-3)" "unprognostic (3.03e-3)" "unprognostic (6.13e-2)" "unprognostic (7.63e-2)" "unprognostic (2.72e-2)" "unprognostic (3.98e-2)" "unprognostic (5.26e-2)" "unprognostic (1.83e-3)" "unprognostic (2.43e-1)" "unprognostic (2.73e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" 24.4 24.4 16.1 23.3 16.1 24.3 23.8 8.5 34.0 26.9 3.2 26.1 14.1 25.9 8.3 27.7 23.5 12.9 30.6 14.5 17.3 24.4 32.7 27.7 20.8 11.5 12.8 30.2 26.8 13.4 20.9 29.4 9.2 24.8 8.5 12.1 22.9 13.6 62.7 33.7 25.5 13.2 2.8 28.7 22.4 24.7 10.3 16.9 24.1 19.1 15.8 25.2 26.7 15.2 46.7 49.1 31.0 58.6 26.4 20.1 32.5 32.5 29.3 28.3 29.6 47.1 71.4 58.5 48.4 36.5 27.6 47.1 30.8 32.4 24.0 51.3 21.4 58.0 41.1 43.7 42.2 53.2 59.7 29.4 34.6 35.2 68.7 18.1 26.1 41.5 91.7 62.7 18.3 55.5 53.6 41.6 58.5 23.4 54.2 63.8 32.5 37.5 22.3 48.8 35.3 31.1 44.7 34.5 40.5 24.4 33.7 38.3 45.0 72.5 32.6 63.3 53.0 43.9 39.0 25.7 39.7 47.0 58.5 3.4 2.2 2.2 2.1 2.8 1.6 3.6 1.8 1.8 1.4 4.3 1.8 1.7 6.5 3.1 2.8 2.6 1.5 1.6 16.1 16.1 8.5 34.0 14.5 17.3 11.5 12.8 9.2 2.8 10.3 15.2 85.9 64.1 52.7 26.8 97.9 117.6 118.4 33.9 80.8 67.0 71.8 54.7 79.5 58.6 33.9 25.8 83.4 219.8 91.6 93.9 25.4 53.6 130.3 83.1 102.6 84.7 113.9 117.0 46.3 67.1 72.4 75.9 56.1 128.2 36.7 95.2 64.6 84.9 60.5 79.1 44.2 71.5 16.2 83.4 101.0 249.3 77.3 87.7 44.4 48.7 72.8 37.0 63.8 28.6 39.3 65.3 62.6 79.7 77.4 137.3 50.7 35.2 30.2 84.2 72.3 103.1 92.0 52.6 48.8 84.7 143.2 254.3 77.4 65.9 71.8 147.0 BRIP1 "BACH1, FANCJ, OF" ENSG00000136492 "BRCA1 interacting protein C-terminal helicase 1" Q9BX63 17 61679139-61863528 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.2;lymphoid tissue: 5.9;testis: 7.0" "Group enriched" "Detected in many" 12 "Early spermatids: 186.2;Late spermatids: 194.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005474 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear membrane" "HPA005474: AB_2667333" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "prognostic favorable (3.45e-5)" "unprognostic (6.85e-4)" "unprognostic (3.09e-1)" "prognostic favorable (3.62e-4)" "unprognostic (2.60e-3)" "unprognostic (5.60e-2)" "unprognostic (5.66e-3)" "unprognostic (6.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.75e-2)" "unprognostic (3.41e-12)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" "unprognostic (3.96e-2)" "unprognostic (3.62e-3)" 0.3 0.3 0.8 1.7 0.6 7.2 0.9 1.3 0.9 0.4 0.0 1.7 2.0 0.8 0.4 1.5 0.3 0.6 0.1 0.5 0.2 0.3 1.6 0.4 2.8 0.3 0.0 1.1 0.3 0.1 0.0 0.8 0.4 0.4 1.9 0.5 0.4 0.2 0.1 2.0 1.9 0.9 0.0 0.7 0.9 7.0 0.2 5.9 0.3 0.1 3.3 0.7 0.6 0.8 26.6 9.4 25.0 14.1 0.9 2.1 5.5 23.6 13.3 24.6 31.8 9.5 8.0 14.9 5.2 4.9 7.7 9.2 12.8 4.5 33.3 3.8 15.8 15.5 14.4 10.5 0.2 20.3 8.8 0.6 0.4 20.2 5.1 3.4 5.0 14.8 11.6 10.5 14.4 88.9 32.5 6.7 5.3 5.9 7.3 19.7 50.1 7.1 3.0 12.8 10.0 24.2 9.4 3.0 3.3 9.1 8.3 7.3 4.5 36.9 26.5 13.5 26.6 6.3 13.3 16.6 7.3 9.3 8.8 1.0 0.1 0.4 0.1 0.0 0.1 0.5 0.3 0.1 0.1 0.6 0.4 0.2 0.3 0.1 0.1 0.1 1.0 0.1 0.8 0.6 1.3 0.9 0.5 0.2 0.3 0.0 0.4 0.0 0.2 0.8 0.2 0.0 0.5 1.0 1.6 2.3 1.3 0.8 0.6 0.3 1.1 1.8 0.6 0.0 4.0 0.0 0.0 2.0 2.0 1.8 0.0 0.3 186.2 0.7 1.7 0.8 0.0 7.4 4.6 0.2 3.0 2.0 2.0 1.6 0.0 15.5 0.4 3.4 1.7 0.0 3.3 1.8 0.0 0.8 1.1 194.1 1.2 1.0 3.6 2.8 0.6 0.2 1.0 1.5 1.0 0.8 0.1 1.2 4.8 0.4 1.4 0.2 0.8 0.2 0.0 2.5 1.8 12.1 6.0 2.9 0.4 0.3 2.3 2.1 4.7 0.7 BRMS1 DKFZP564A063 ENSG00000174744 "BRMS1 transcriptional repressor and anoikis regulator" Q9HCU9 11 66337333-66345125 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010824, HPA019637" Approved Approved Centrosome NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "CAB010824: , HPA019637: AB_1845448" "unprognostic (1.75e-1)" "unprognostic (2.64e-2)" "unprognostic (2.01e-1)" "unprognostic (4.31e-2)" "unprognostic (1.72e-2)" "unprognostic (5.50e-2)" "prognostic unfavorable (6.74e-4)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (4.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (5.67e-3)" "unprognostic (2.54e-1)" "unprognostic (6.32e-2)" "unprognostic (1.61e-1)" 27.2 28.1 25.3 24.1 27.0 52.2 27.1 27.2 28.5 22.0 26.9 28.9 26.0 20.5 17.5 36.7 20.0 18.0 26.0 26.6 25.4 35.0 29.1 25.0 32.2 27.4 27.1 19.9 40.9 19.3 17.9 19.5 26.8 33.9 19.2 9.1 30.5 18.3 38.0 41.5 29.6 13.1 26.5 38.3 31.6 31.5 27.1 28.7 26.5 13.8 25.6 25.1 25.8 28.0 80.3 102.4 33.8 56.6 35.1 36.1 47.8 54.4 58.9 95.9 63.9 84.1 51.2 53.5 78.9 53.8 82.5 91.7 64.9 99.2 45.0 63.9 53.9 49.2 54.2 62.1 65.1 71.3 54.9 41.2 104.5 97.0 72.2 29.1 59.9 60.1 59.0 24.3 58.0 128.9 87.5 169.1 73.3 61.2 95.3 73.2 62.2 100.0 60.1 45.6 70.8 57.0 67.2 68.6 180.9 24.6 83.5 43.7 58.2 71.9 68.2 117.1 68.8 50.2 53.8 85.3 93.0 46.2 78.8 45.6 79.4 80.8 61.1 77.3 65.1 79.2 65.2 58.6 62.4 75.6 56.3 54.3 104.2 51.3 69.9 67.3 79.9 67.3 25.3 27.0 27.2 28.5 26.6 25.4 27.4 27.1 26.8 26.5 27.1 28.0 27.2 16.0 26.9 4.2 42.7 58.1 28.5 45.0 33.6 12.3 31.7 27.6 11.7 40.0 22.6 22.0 6.2 61.5 37.1 109.0 54.8 72.6 7.4 25.6 16.6 30.8 32.3 33.7 2.9 117.9 68.5 22.9 33.1 18.6 27.8 21.4 28.2 21.5 67.6 11.8 2.2 54.0 32.6 51.3 41.7 9.9 22.4 39.1 28.4 5.6 68.3 31.7 56.7 3.0 5.1 85.7 85.6 14.7 30.5 40.6 80.5 51.1 22.2 14.9 6.6 23.1 27.3 35.8 39.4 32.2 60.0 71.7 42.5 21.1 61.3 29.8 BTG1 APRO2 ENSG00000133639 "BTG anti-proliferation factor 1" P62324 12 92140278-92145846 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2751.6;Langerhans cells: 2893.3;Suprabasal keratinocytes: 3004.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 33.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005972 Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA005972: AB_1078303" "prognostic favorable (4.36e-5)" "unprognostic (1.43e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.50e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (5.79e-2)" "unprognostic (9.81e-2)" 91.5 36.9 1.9 19.8 2.0 93.9 80.1 33.5 4.1 62.3 1.4 38.9 8.5 45.6 1.5 29.5 55.9 7.1 45.2 2.5 4.6 52.4 69.7 55.5 23.8 3.6 2.6 45.6 63.7 8.3 26.2 6.2 3.7 40.5 4.8 5.2 30.5 4.5 20.5 120.6 58.4 8.2 3.5 92.2 39.3 12.4 3.1 20.1 21.9 3.7 18.2 38.5 60.1 3.0 5.7 5.4 3.5 0.9 13.4 16.9 3.2 8.0 6.3 2.3 2.3 2.4 1.6 5.7 1.5 3.3 3.5 3.9 1.6 3.0 2.2 9.8 8.8 0.8 2.9 1.3 15.0 3.7 1.9 14.1 11.9 4.5 11.7 8.5 5.0 2.4 4.6 7.1 3.4 3.7 5.5 9.4 2.2 3.0 11.0 15.2 2.4 1.5 5.5 6.5 3.4 7.8 6.1 4.4 17.3 2.1 21.5 7.7 2.6 3.9 1.3 3.6 3.7 14.0 6.3 8.9 3.1 2.4 4.6 36.2 21.8 151.8 22.8 16.2 27.8 92.4 47.3 40.7 9.2 105.5 133.1 53.6 75.9 68.8 22.8 8.0 66.8 51.3 1.9 2.0 33.5 4.1 2.5 4.6 3.6 2.6 3.7 3.5 3.1 3.0 1186.6 96.1 185.4 12.1 2512.8 2751.6 1030.9 206.6 912.9 592.7 607.5 573.8 119.5 1009.4 140.4 174.7 196.0 412.8 1907.2 672.9 320.8 388.1 411.8 216.7 258.8 709.0 452.4 230.7 7.9 255.8 416.3 529.1 406.7 264.7 286.6 197.4 339.1 274.9 361.4 424.0 20.6 373.8 193.3 564.3 2893.3 213.7 287.1 1251.4 983.6 31.9 1241.2 877.6 1354.3 22.1 8.4 364.4 668.7 241.9 758.5 791.3 667.9 162.6 53.0 377.2 539.0 870.7 723.5 130.1 101.5 508.7 3004.2 1342.7 2354.0 786.4 410.9 1513.3 BTG2 "APRO1, MGC126063, MGC126064, PC3, TIS21" ENSG00000159388 "BTG anti-proliferation factor 2" P78543 1 203305491-203309602 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 965.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 161.8;HMC-1: 160.8;RT4: 131.3;U-266/70: 259.8;U-266/84: 141.2" "Low region specificity" "Detected in all" HPA002355 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA002355: AB_1078304" "prognostic favorable (8.53e-4)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" "unprognostic (4.81e-3)" "unprognostic (5.91e-2)" "unprognostic (1.46e-1)" "unprognostic (2.47e-1)" "unprognostic (7.87e-3)" "unprognostic (4.72e-1)" "unprognostic (1.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.18e-2)" "unprognostic (4.46e-2)" "unprognostic (6.22e-2)" "unprognostic (4.34e-1)" "unprognostic (1.17e-1)" "unprognostic (2.86e-3)" 274.5 244.6 38.3 124.3 40.7 309.3 118.8 58.4 45.0 101.7 36.7 231.5 88.5 91.9 41.5 313.4 355.0 157.8 256.3 35.1 49.0 132.2 20.8 105.0 122.0 61.8 42.1 554.9 488.9 37.4 209.2 106.7 43.6 265.9 205.7 152.6 75.1 182.9 210.7 134.4 111.1 213.7 49.3 107.1 244.5 10.2 42.4 334.6 201.2 287.1 132.3 279.9 79.1 42.1 4.3 6.1 10.9 4.5 13.4 9.8 92.9 11.2 21.4 2.8 10.5 8.8 1.6 161.8 7.8 3.5 1.8 69.5 39.6 42.6 5.2 10.8 20.3 84.5 12.3 18.4 29.5 0.4 160.8 10.1 76.7 10.3 18.7 9.5 57.6 8.2 40.6 106.9 28.1 3.6 18.1 5.4 4.9 1.7 1.2 11.4 36.5 84.3 5.3 131.3 1.9 11.3 8.6 3.6 1.4 80.0 9.0 10.1 14.3 0.3 18.2 2.9 0.6 259.8 141.2 103.4 2.2 4.1 6.3 8.4 19.7 23.1 10.0 27.1 14.8 29.9 10.9 10.2 11.5 29.0 17.5 12.6 77.1 12.7 35.6 38.6 11.2 19.7 38.3 40.7 58.4 45.0 35.1 49.0 61.8 42.1 43.6 49.3 42.4 42.1 555.8 157.0 241.8 6.5 330.1 230.2 464.4 311.4 548.7 25.4 355.1 276.7 274.8 48.6 128.5 187.6 29.2 50.0 343.9 345.8 15.6 113.2 1.4 336.7 211.7 196.4 965.1 127.6 2.9 163.7 16.6 352.8 562.2 643.2 369.3 40.6 148.2 6.5 120.1 3.3 2.0 617.1 264.5 98.8 183.6 3.1 72.7 227.0 120.9 25.3 47.5 478.8 58.7 4.5 10.4 55.9 399.9 55.3 725.2 230.1 397.5 13.9 88.5 38.9 124.9 537.5 305.0 1.8 1.7 343.8 447.9 138.0 300.8 278.6 360.7 211.8 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008419 Supported Cytosol Yes Yes "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 0.4 0.5 0.1 6.7 0.1 17.8 1.6 0.3 0.2 1.0 7.7 4.6 4.7 1.2 0.3 5.2 0.6 0.6 0.3 0.3 0.1 0.3 0.4 1.0 12.6 0.0 0.1 0.2 0.2 0.2 0.1 3.4 0.1 0.4 6.0 0.1 0.9 0.2 0.0 3.5 4.1 2.1 0.0 3.1 2.4 22.2 0.2 35.7 0.5 0.0 15.0 1.5 1.7 0.0 66.5 32.8 103.0 41.5 2.5 7.1 33.2 60.9 34.2 64.6 55.7 48.1 25.0 59.7 33.5 22.7 59.0 72.6 98.8 33.2 70.5 51.8 52.1 86.4 83.6 45.5 0.2 79.0 45.7 1.6 2.0 39.2 37.1 12.9 47.7 66.5 76.4 61.7 65.6 22.5 62.5 48.9 70.2 55.6 36.8 66.5 83.7 45.2 19.9 33.1 67.1 40.8 38.0 35.9 13.3 45.1 41.9 40.9 27.6 49.3 51.8 49.2 55.5 32.1 58.2 95.6 26.3 87.8 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 3.2 1.1 0.3 1.8 0.8 0.3 1.0 1.8 0.7 0.9 2.0 0.8 0.0 1.9 0.0 0.0 5.4 0.6 1.8 0.0 0.4 3.0 0.9 1.4 1.0 0.0 23.5 0.7 0.0 6.7 2.4 5.6 2.1 0.0 12.9 1.1 0.3 5.2 0.0 0.7 2.5 0.0 1.9 1.7 3.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.5 0.4 12.6 0.3 0.3 0.1 0.2 0.2 6.6 0.2 1.7 79.2 26.8 6.9 0.3 0.8 1.8 0.8 5.4 0.6 C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA 410000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" 79.3 135.4 85.5 84.1 85.7 121.2 108.7 91.5 118.3 58.4 119.6 140.3 95.9 66.4 68.3 138.6 74.5 48.7 126.3 89.5 94.3 136.4 134.5 54.7 115.7 89.6 92.3 52.7 72.9 127.7 81.3 75.8 93.2 63.9 141.6 86.7 66.2 73.1 174.2 81.3 78.4 80.9 93.1 73.5 74.3 62.5 90.7 98.5 65.1 160.1 135.6 108.4 73.9 97.3 443.8 671.0 233.0 378.0 169.8 207.7 313.7 330.4 268.5 751.4 458.8 646.8 143.7 941.8 317.8 251.3 271.3 385.8 756.7 448.9 689.8 216.6 1300.5 433.9 312.4 762.2 269.9 535.6 331.0 231.4 404.1 414.6 593.1 181.1 390.0 548.2 526.1 234.4 296.1 308.6 766.4 385.6 525.9 497.2 396.7 601.2 329.1 515.0 440.5 328.7 186.0 348.0 271.4 344.4 483.6 232.1 218.1 267.1 231.1 240.1 219.7 275.9 729.9 122.0 201.2 415.0 229.3 506.2 376.8 68.1 197.6 49.9 217.1 212.0 283.5 330.1 239.0 215.4 389.5 289.8 289.7 245.7 15.5 240.7 166.4 325.4 203.6 432.6 85.5 85.7 91.5 118.3 89.5 94.3 89.6 92.3 93.2 93.1 90.7 97.3 101.6 28.9 30.5 10.7 153.1 243.1 229.0 283.3 165.0 70.5 157.3 209.4 84.8 102.9 107.8 82.8 27.1 323.8 115.0 105.6 313.1 248.0 75.1 106.7 149.9 108.2 79.2 183.1 10.8 205.1 457.9 101.0 94.8 85.9 62.2 131.6 75.3 128.5 202.7 60.6 11.6 190.2 154.6 85.3 129.8 89.5 119.6 101.8 156.5 10.3 170.3 105.2 93.7 11.1 16.1 199.3 128.5 98.6 197.4 255.1 78.9 444.1 65.1 79.9 85.5 101.6 189.1 79.3 237.3 284.4 255.3 179.0 105.5 354.3 364.0 253.8 C3orf70 ENSG00000187068 "Chromosome 3 open reading frame 70" A6NLC5 3 185076838-185153060 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;smooth muscle: 14.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Bipolar cells: 76.8;Melanocytes: 39.2;Oligodendrocyte precursor cells: 143.2;Peritubular cells: 49.7" "Cancer enhanced" "Detected in many" "glioma: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 3.9;SCLC-21H: 16.4;SK-BR-3: 7.2;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041861 Uncertain Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA041861: AB_10804119" "unprognostic (1.45e-1)" "unprognostic (2.17e-3)" "unprognostic (3.92e-3)" "unprognostic (2.77e-1)" "unprognostic (2.31e-1)" "unprognostic (6.62e-4)" "unprognostic (5.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (5.98e-3)" "unprognostic (9.91e-2)" "prognostic unfavorable (6.40e-6)" "unprognostic (1.06e-1)" "unprognostic (8.48e-2)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" 2.2 0.8 10.8 2.4 8.5 0.1 1.3 7.2 8.8 3.1 0.0 11.1 2.6 9.8 2.6 5.1 5.2 2.2 2.0 9.9 9.1 0.5 0.3 0.9 0.4 15.9 11.5 2.3 0.2 2.1 0.8 1.3 10.1 5.1 4.1 3.9 3.0 8.4 0.5 1.5 3.6 14.8 13.6 2.1 2.8 4.0 12.0 0.3 1.1 0.6 0.6 4.9 2.0 14.0 0.0 0.1 1.9 0.0 0.0 0.0 0.1 2.6 0.1 0.4 0.0 1.2 0.0 0.0 0.0 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.6 2.2 0.1 0.5 0.0 0.3 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.8 2.0 0.1 0.0 3.9 0.0 0.0 0.4 16.4 0.1 0.8 7.2 0.4 0.0 0.4 1.8 0.6 0.0 1.9 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.9 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.0 10.8 8.5 7.2 8.8 9.9 9.1 15.9 11.5 10.1 13.6 12.0 14.0 5.1 0.0 0.0 45.7 1.0 4.1 0.3 0.0 0.6 76.8 1.0 0.5 1.6 0.0 0.0 0.0 0.0 10.8 0.0 9.1 0.0 0.1 1.2 0.1 2.3 4.4 1.2 0.0 13.8 0.2 0.6 3.8 0.0 0.1 0.0 3.9 6.8 0.0 4.0 3.3 19.4 8.8 0.0 0.6 0.7 1.5 3.4 0.3 39.2 6.5 0.6 2.5 0.0 143.2 10.1 0.5 2.2 49.7 0.1 0.3 4.6 0.1 0.0 7.3 6.6 1.3 15.4 6.8 12.5 0.2 1.8 0.8 0.2 1.8 6.3 0.3 C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 665.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 127.2;Hepatocytes: 376.9;Late spermatids: 54.8;Leydig cells: 120.2;Respiratory ciliated cells: 58.0" "Group enriched" "Detected in many" 7 "liver cancer: 49.0;pancreatic cancer: 12.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 4.5;ASC TERT1: 6.2;HSkMC: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043823, CAB069427" Enhanced "Secreted to blood" NA NA 45000000000 9200000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB069427: AB_1614336, HPA043823: AB_10960262" "unprognostic (9.79e-2)" "unprognostic (1.96e-2)" "unprognostic (5.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (4.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (3.04e-3)" "prognostic favorable (4.31e-4)" "unprognostic (2.69e-4)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" 12.8 1.1 0.2 0.0 0.2 0.0 5.4 0.2 0.1 0.8 1.6 0.8 0.9 0.4 0.9 0.3 43.9 12.0 57.1 0.2 0.6 4.4 665.9 3.2 0.4 0.0 1.7 6.2 42.7 0.1 0.7 2.8 0.2 0.9 0.6 0.0 0.9 0.6 0.6 0.6 1.4 0.9 0.1 0.3 2.2 4.2 0.8 0.6 2.0 0.7 0.5 0.9 0.6 0.6 0.0 0.0 0.0 0.0 4.5 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.2 0.6 0.0 1.7 0.2 0.1 0.8 0.6 0.8 0.0 0.0 0.7 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 20.9 127.2 7.5 0.0 0.0 0.0 0.1 0.3 0.0 9.3 11.3 37.5 0.8 0.9 0.0 8.0 1.4 0.4 0.0 6.7 0.0 0.7 0.0 0.1 5.0 376.9 0.0 0.0 2.7 1.0 0.0 9.7 0.3 54.8 120.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.5 1.3 0.4 0.0 0.0 11.6 0.8 58.0 0.0 0.0 0.2 0.4 0.4 0.1 0.0 0.0 0.0 0.4 0.5 0.6 0.0 C7 ENSG00000112936 "Complement C7" P10643 5 40909497-40984643 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 735.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 578.4;Hepatic stellate cells: 662.5;Leydig cells: 1058.5;Sertoli cells: 309.0;Theca cells: 503.1" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 116.5;HHSteC: 155.1;HSkMC: 212.1;SH-SY5Y: 146.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 13.7" HPA001465 Approved "Secreted to blood" NA NA 48000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" 470.9 607.7 2.6 21.7 3.5 0.2 46.4 2.6 9.6 118.5 13.6 165.3 19.3 124.6 163.6 52.9 377.3 211.7 558.7 2.8 2.5 298.1 110.6 206.7 99.2 4.4 2.7 735.4 149.8 15.0 23.1 359.2 3.0 101.6 32.5 1.5 18.0 105.7 4.3 12.6 139.8 256.3 4.3 138.2 120.2 28.0 3.0 32.2 105.1 1.6 22.5 122.1 118.3 3.0 0.0 0.0 0.0 0.0 116.5 16.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 155.1 0.0 0.0 212.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 146.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.6 3.5 2.6 9.6 2.8 2.5 4.4 2.7 3.0 4.3 3.0 3.0 7.9 6.4 4.1 0.0 1.4 0.6 0.5 0.0 1.8 2.1 1.2 0.3 56.7 7.2 2.5 0.0 0.0 0.2 0.1 0.4 0.0 0.2 4.7 0.5 7.9 127.6 54.8 26.7 0.1 1.3 0.1 578.4 0.0 0.2 1.3 2.7 662.5 8.3 0.5 43.7 0.3 1.3 0.0 14.5 4.2 29.8 1058.5 1.5 0.0 58.1 0.6 3.7 0.0 0.0 0.0 0.9 0.9 18.0 1.0 1.3 0.2 0.1 0.0 0.9 309.0 2.2 23.7 2.6 2.5 6.5 0.6 0.3 1.2 503.1 3.0 0.8 CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.3;parathyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Astrocytes: 92.7;Enteroendocrine cells: 35.2;Gastric mucus-secreting cells: 40.2;Oligodendrocyte precursor cells: 129.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cell line enhanced" "Detected in some" "HEK 293: 10.1;JURKAT: 11.0;K-562: 20.3;NB-4: 12.3;OE19: 17.4" "Region enriched" "Detected in all" 38 "cerebellum: 1260.5" "Region enriched" "Detected in all" 9 "cerebellum: 86.3" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025545: , CAB047309: , HPA024748: AB_1846003" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-3)" "unprognostic (6.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.85e-2)" "unprognostic (3.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.79e-5)" "unprognostic (3.23e-2)" "unprognostic (1.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" 1.6 0.9 5.2 0.3 5.8 0.5 4.6 18.3 5.6 4.3 2.0 1.3 1.0 1.9 10.2 0.2 1.5 0.3 4.3 4.4 5.3 5.3 0.0 0.9 0.4 4.7 4.9 0.2 1.9 40.1 8.5 6.2 5.0 1.5 2.0 2.3 3.7 0.2 1.2 0.3 1.0 0.5 3.1 0.8 4.4 4.1 5.1 1.3 0.3 2.3 0.3 0.6 0.3 4.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.1 0.0 10.1 4.5 0.0 0.0 3.6 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 11.0 20.3 0.2 0.0 0.0 3.3 12.3 0.2 17.4 0.0 0.0 0.0 0.2 0.4 0.8 5.1 0.0 0.0 1.1 0.0 2.0 4.5 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.5 76.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 5.2 5.8 18.3 5.6 4.4 5.3 4.7 4.9 5.0 3.1 5.1 4.0 22.0 0.0 4.8 92.7 1.6 1.0 0.4 4.1 0.0 8.2 15.6 10.3 4.7 0.0 5.7 3.7 0.0 8.3 10.9 2.0 3.9 8.1 9.9 9.8 2.4 16.7 35.2 13.5 4.7 6.0 0.3 4.0 40.2 26.2 0.0 1.1 0.0 0.0 9.9 0.0 25.6 25.0 6.1 1.9 1.1 4.9 1.5 1.1 7.2 18.7 0.0 2.6 1.0 129.7 0.4 1.6 3.5 1.5 14.0 2.1 0.3 0.0 1.2 1.0 0.0 0.8 2.3 3.8 5.5 0.2 0.4 1.4 0.7 3.1 3.3 1.5 CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.2;Inhibitory neurons: 354.1;Microglial cells: 126.5;Oligodendrocyte precursor cells: 197.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 3.7" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "HMC-1: 22.7;RPMI-8226: 55.5;SK-BR-3: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020215 Uncertain Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane" "HPA020215: AB_1845860" "unprognostic (5.85e-2)" "unprognostic (4.90e-3)" "unprognostic (5.09e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (2.32e-2)" "unprognostic (2.95e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-3)" "unprognostic (1.53e-1)" "prognostic favorable (8.34e-8)" "unprognostic (1.14e-1)" "unprognostic (3.05e-2)" "unprognostic (8.09e-3)" "unprognostic (6.70e-3)" 0.1 6.6 7.0 0.2 4.3 0.7 1.8 2.3 10.4 6.0 0.0 1.5 1.7 3.7 7.3 0.5 7.7 2.0 0.6 3.6 0.8 2.2 1.0 3.7 0.1 0.0 1.2 0.5 2.8 1.2 3.5 0.6 0.4 3.0 1.5 4.3 0.5 1.8 0.2 0.7 2.4 0.7 3.5 1.8 0.8 1.6 6.1 0.2 2.9 0.2 0.1 0.6 0.1 6.0 0.0 0.5 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 2.7 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.1 0.1 0.0 0.4 0.9 0.0 0.0 0.2 55.5 0.5 3.6 4.7 2.1 0.3 10.1 1.1 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 4.3 2.3 10.4 3.6 0.8 0.0 1.2 0.4 3.5 6.1 6.0 0.6 3.2 36.2 7.8 0.6 0.9 0.8 4.6 2.2 33.3 7.2 1.8 2.3 10.0 9.1 1.8 35.5 0.9 0.5 3.0 0.0 7.2 4.9 4.3 40.1 2.4 59.4 2.7 251.2 2.3 0.2 3.4 5.1 3.3 12.6 1.7 0.0 3.4 0.2 8.4 354.1 3.8 2.0 0.8 4.0 8.3 4.4 2.1 5.4 126.5 0.5 4.0 0.0 197.5 29.9 3.8 5.6 27.1 0.1 1.7 9.5 2.7 9.5 12.9 0.0 0.2 8.6 1.0 3.7 0.5 1.0 0.3 1.7 9.6 7.6 0.9 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217369-27243943 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA065158, HPA069341" Supported Supported Cytosol NA No 260000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "CAB007781: AB_562057, HPA065158: , HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 15.0 13.5 12.7 12.4 14.1 9.0 14.9 12.7 15.5 19.8 12.2 16.5 8.5 23.8 9.9 19.2 19.3 7.7 11.6 12.3 12.8 18.0 27.8 12.3 14.9 13.8 13.5 22.3 22.3 5.9 18.7 7.5 14.5 15.2 7.8 5.0 12.3 8.8 10.3 18.7 16.1 11.9 12.7 20.1 14.0 22.2 14.2 11.6 15.8 5.9 10.5 16.9 15.8 15.2 75.2 66.4 28.9 58.4 46.1 37.6 22.9 31.0 21.4 38.3 27.0 75.7 29.2 66.4 27.4 28.5 29.6 41.4 85.7 41.1 28.5 43.8 69.2 95.2 55.0 40.0 23.0 75.7 46.2 28.8 33.1 55.7 63.0 17.8 41.6 60.6 68.3 36.0 34.2 74.8 48.7 112.0 69.7 31.3 49.7 84.0 86.5 69.5 28.6 37.6 57.9 29.1 43.3 30.5 37.4 21.3 23.9 31.3 37.7 57.7 47.5 45.5 63.5 74.0 51.8 135.2 23.3 71.7 51.0 0.0 0.8 0.4 3.1 1.5 2.5 3.4 4.4 5.2 1.9 3.1 2.8 2.8 0.5 2.7 0.9 3.4 5.9 2.0 12.7 14.1 12.7 15.5 12.3 12.8 13.8 13.5 14.5 12.7 14.2 15.2 4.2 3.2 3.9 12.7 5.3 3.7 4.3 5.0 5.7 10.6 7.1 8.6 8.3 10.0 4.7 1.8 16.7 5.9 3.9 3.9 0.0 6.1 1.5 2.9 7.9 5.1 6.6 9.7 5.6 3.7 6.6 7.0 6.1 4.3 4.5 16.9 3.3 6.6 7.7 6.7 5.7 5.8 0.0 3.0 1.9 1.9 6.2 3.6 3.6 6.5 4.7 4.1 5.2 8.5 7.4 5.9 1.9 9.8 7.3 8.0 2.5 2.0 3.5 6.8 0.0 8.2 5.2 5.6 12.1 6.2 3.4 2.2 5.1 9.7 7.5 2.2 CALCA "CALC1, CGRP, CGRP-alpha" ENSG00000110680 "Calcitonin related polypeptide alpha" "P01258, P06881" 11 14966668-14972351 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, Transporters" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 178.3;thyroid gland: 154.2" "Cell type enriched" "Detected in some" 64 "Ionocytes: 2368.1" "Cancer enriched" "Detected in many" 7 "lung cancer: 64.7" "Region enhanced" "Detected in many" "pons: 34.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "pons and medulla: 57.9" "HPA059886, HPA064453" Enhanced Supported "Secreted to blood" NA NA 51500 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA059886: , HPA064453: " "unprognostic (1.97e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (5.99e-2)" "unprognostic (2.42e-1)" "unprognostic (1.17e-1)" "unprognostic (6.45e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (3.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.74e-2)" "unprognostic (2.53e-3)" "unprognostic (1.02e-2)" 0.7 0.2 0.6 1.5 0.6 0.0 0.2 0.6 0.5 0.2 0.0 0.6 0.0 0.2 0.0 0.1 0.3 0.2 1.1 0.3 0.8 46.4 37.5 2.4 0.1 20.9 7.0 0.1 0.4 178.3 0.8 0.0 34.4 2.5 0.1 0.0 0.1 0.0 0.5 0.0 0.1 1.5 1.5 3.0 0.2 0.2 0.6 0.3 154.2 0.0 0.0 4.3 0.4 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.5 0.3 0.8 20.9 7.0 34.4 1.5 0.6 10.4 0.1 0.0 0.0 0.0 0.2 0.3 0.4 35.4 0.0 0.0 0.0 0.1 0.4 0.0 0.3 36.8 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.3 0.0 0.0 0.7 4.4 0.3 0.0 0.0 0.0 2368.1 0.0 4.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.2 0.0 0.0 0.4 5.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 CALR "cC1qR, CRT, FLJ26680, RO, SSA" ENSG00000179218 Calreticulin P27797 19 12938578-12944489 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1717.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001513, HPA002242, CAB019952, CAB079775" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 210000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "CAB001513: , CAB019952: AB_2069792, CAB079775: AB_303403, HPA002242: AB_1078384" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.25e-2)" "unprognostic (9.44e-3)" "unprognostic (6.93e-2)" "unprognostic (2.47e-2)" "unprognostic (4.60e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.07e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (5.27e-2)" 295.5 257.6 201.7 352.9 213.4 554.9 218.9 238.0 213.5 256.3 324.0 304.6 287.3 275.8 647.7 338.2 266.7 164.1 303.2 203.5 239.7 296.9 782.3 308.9 230.0 260.4 230.1 272.2 319.7 292.2 284.5 403.3 254.5 277.9 336.7 96.2 299.3 247.2 119.8 189.3 277.2 349.7 237.7 277.3 300.6 165.2 267.3 245.3 702.9 104.7 319.4 252.2 236.6 274.2 1681.4 673.6 832.5 1984.9 1110.8 861.5 724.6 2075.3 1160.8 839.6 1280.4 1044.2 1353.5 1087.2 1960.0 2528.4 1064.5 672.1 906.1 1476.5 800.7 730.0 588.1 894.3 689.0 1619.6 2667.5 3638.5 1171.8 946.8 638.7 1222.3 957.7 1472.5 1507.8 743.1 814.5 536.3 911.7 1222.3 1040.0 2511.9 808.7 952.0 970.1 777.0 770.8 1329.9 1138.3 846.9 312.4 668.4 1438.7 769.8 472.6 789.9 1014.4 1558.9 1460.6 1113.2 666.2 1533.6 938.3 644.3 569.7 985.8 1567.6 1616.3 1258.1 67.5 72.8 39.7 172.8 147.8 119.3 90.0 99.7 130.0 76.3 77.5 73.0 134.4 23.8 103.1 122.7 215.6 83.4 75.8 201.7 213.4 238.0 213.5 203.5 239.7 260.4 230.1 254.5 237.7 267.3 274.2 385.2 147.4 160.7 34.6 385.7 261.7 336.3 217.3 221.4 76.8 214.9 140.8 43.7 163.0 175.4 222.5 127.2 652.9 515.5 524.4 64.6 582.7 27.8 206.3 364.2 305.6 353.6 266.1 14.2 285.5 1717.5 422.5 289.5 348.2 207.4 341.6 312.7 612.4 789.3 35.3 23.8 595.1 93.6 208.8 433.2 30.6 318.7 378.4 213.5 31.9 229.9 316.5 360.5 28.6 31.1 410.2 462.8 311.1 1059.6 426.1 377.8 182.8 147.5 167.7 203.8 224.2 328.9 276.1 306.6 245.5 213.5 964.4 345.8 399.4 471.4 329.6 CAMTA1 KIAA0833 ENSG00000171735 "Calmodulin binding transcription activator 1" Q9Y6Y1 1 6785454-7769706 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036342, HPA036343" Approved Supported Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA036342: AB_2675072, HPA036343: AB_10671839" "unprognostic (1.11e-1)" "unprognostic (6.31e-2)" "unprognostic (5.80e-2)" "unprognostic (4.14e-3)" "unprognostic (3.10e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "prognostic favorable (4.10e-4)" "unprognostic (3.90e-3)" "unprognostic (8.84e-2)" "unprognostic (1.35e-3)" "unprognostic (2.17e-2)" "unprognostic (9.19e-3)" "unprognostic (1.42e-1)" "unprognostic (9.03e-3)" 37.1 43.7 56.2 23.6 55.3 26.5 38.7 63.4 75.8 33.0 29.4 71.8 52.8 40.1 81.7 37.5 36.0 30.4 114.0 55.0 68.6 68.4 70.5 36.7 27.3 69.4 66.0 35.4 26.4 43.3 35.5 26.4 68.7 47.0 48.5 68.2 50.5 50.5 101.6 26.0 41.1 42.4 61.5 30.7 45.2 44.5 66.4 31.9 52.0 104.7 33.5 56.5 35.2 60.8 67.6 37.2 101.2 51.7 51.2 77.6 28.4 71.0 54.7 75.3 63.1 45.1 83.2 55.5 54.6 75.2 50.3 40.8 53.6 73.7 106.5 41.8 57.8 62.7 85.1 89.6 83.0 48.2 43.6 52.5 50.2 54.5 83.0 64.6 85.1 77.7 44.8 73.2 87.9 65.0 64.6 130.9 70.2 85.2 43.2 42.5 90.2 123.7 103.4 38.7 104.2 83.7 50.4 74.1 113.9 72.3 40.2 59.4 50.1 53.1 44.9 55.3 45.2 55.2 74.3 153.2 79.6 107.4 30.7 80.1 74.7 70.5 25.8 48.5 28.3 48.1 39.8 32.0 73.4 41.8 32.2 28.1 15.4 26.7 37.9 77.5 45.6 46.3 56.2 55.3 63.4 75.8 55.0 68.6 69.4 66.0 68.7 61.5 66.4 60.8 142.1 54.5 48.8 314.7 74.3 309.7 340.6 306.6 169.0 106.7 231.7 283.2 565.2 101.5 135.3 191.3 252.3 69.8 44.3 198.3 418.7 180.1 166.1 84.1 80.3 155.8 130.8 81.8 346.1 206.3 144.9 134.4 63.2 99.8 55.2 205.4 106.1 239.0 106.3 158.2 479.3 185.8 223.8 95.5 254.0 137.9 76.4 122.0 238.3 117.1 172.9 112.3 38.1 330.3 227.5 184.2 234.5 128.6 87.9 486.4 251.7 750.7 117.1 156.2 138.1 91.1 233.2 151.0 211.0 158.9 282.7 88.1 68.2 137.8 186.5 413.7 CANT1 "SCAN-1, SHAPY" ENSG00000171302 "Calcium activated nucleotidase 1" Q8WVQ1 17 78991716-79009867 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 139.5;Intestinal goblet cells: 155.6;Syncytiotrophoblasts: 101.5;Undifferentiated cells: 100.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 445.4;T-47d: 282.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019627, HPA019639, HPA022818" Enhanced Supported "Golgi apparatus" NA Yes 3300000 "Cluster 52: Eosinophils - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA019627: AB_1845969, HPA019639: AB_1845970, HPA022818: AB_1845971" "unprognostic (1.98e-2)" "unprognostic (2.49e-2)" "unprognostic (1.50e-2)" "unprognostic (5.36e-2)" "unprognostic (2.13e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.41e-4)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.21e-4)" "unprognostic (7.04e-2)" "unprognostic (5.06e-2)" "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" 15.8 23.9 10.4 24.7 12.4 19.1 25.4 13.6 11.3 32.3 13.8 89.2 51.9 17.4 8.7 44.8 18.2 25.2 17.0 11.1 12.6 16.1 17.3 16.4 15.2 14.6 14.5 14.6 19.6 24.5 17.5 25.9 13.9 71.8 82.8 7.4 62.7 32.4 14.9 14.9 55.5 15.5 13.8 26.5 51.1 20.7 14.5 14.7 13.9 12.4 15.1 16.7 21.7 17.8 106.5 112.1 31.9 46.3 29.7 35.2 38.9 66.0 51.3 66.7 55.9 53.8 99.6 25.3 36.1 46.1 83.0 53.7 27.1 49.8 68.4 43.0 46.4 33.7 34.1 45.9 25.0 33.0 51.6 33.7 32.4 62.7 34.2 40.9 116.1 42.5 42.3 43.2 46.4 58.4 50.2 19.8 22.1 445.4 103.1 27.6 51.8 29.8 29.8 53.5 45.6 45.4 33.9 227.2 50.2 50.3 282.6 38.6 56.6 101.9 90.5 46.4 83.1 48.9 43.8 24.3 64.4 24.9 65.3 6.3 4.0 8.7 5.5 4.4 5.7 3.9 4.3 4.8 3.8 2.5 4.1 4.1 17.4 3.1 3.0 2.7 3.6 4.6 10.4 12.4 13.6 11.3 11.1 12.6 14.6 14.5 13.9 13.8 14.5 17.8 12.6 28.9 20.6 5.9 11.8 16.6 15.3 16.8 6.8 6.4 49.9 16.3 13.3 14.3 15.1 12.9 14.6 36.6 8.9 139.5 3.9 34.7 14.0 10.7 13.1 16.3 51.0 15.2 4.1 28.8 39.4 13.5 38.2 19.0 5.7 20.0 41.7 14.4 24.9 5.0 5.2 155.6 16.2 12.4 9.5 15.7 11.8 14.2 14.2 3.7 18.1 8.1 11.3 5.0 10.2 37.7 55.8 7.5 16.6 33.4 39.4 6.7 9.7 8.7 6.6 9.5 13.3 23.9 5.8 12.0 13.1 101.5 11.1 11.3 100.2 19.4 CANX "CNX, IP90, P90" ENSG00000127022 Calnexin P27824 5 179678628-179731641 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 817.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 528.3;SK-MEL-30: 790.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004738, HPA009433, HPA009696" Enhanced Enhanced "Endoplasmic reticulum" NA NA 13000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "CAB004738: AB_626784, HPA009433: AB_1078380, HPA009696: AB_1078379" "unprognostic (6.56e-2)" "unprognostic (9.34e-3)" "prognostic favorable (1.38e-4)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" "unprognostic (1.41e-2)" "unprognostic (4.66e-3)" "unprognostic (8.57e-2)" "unprognostic (4.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.17e-3)" "unprognostic (4.48e-2)" "unprognostic (2.28e-1)" "unprognostic (1.87e-1)" "unprognostic (7.12e-2)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.15e-1)" 128.3 112.8 15.0 36.3 17.6 76.0 110.6 18.8 31.1 121.4 25.1 108.7 45.0 137.7 171.7 106.7 109.8 6.2 137.5 13.8 24.1 121.4 193.2 112.7 18.4 24.7 24.1 129.6 209.7 9.6 96.5 75.0 20.2 96.0 62.6 68.0 123.3 17.8 111.6 83.5 97.4 85.0 19.2 73.2 115.2 75.0 17.9 9.0 159.2 53.6 16.6 112.0 95.6 22.6 13.0 91.5 89.5 53.0 295.4 229.3 37.9 261.4 342.8 341.2 298.2 148.2 49.6 309.3 351.0 127.8 121.4 18.7 120.2 121.1 405.9 64.6 6.3 63.0 247.8 22.9 399.9 82.9 50.0 39.1 313.5 118.6 528.3 56.1 93.9 23.9 43.2 99.9 39.9 51.2 40.9 15.1 9.4 11.7 6.4 43.2 71.3 24.9 252.1 82.8 24.4 8.0 62.7 16.7 790.3 182.7 267.3 16.3 234.7 49.9 56.5 36.1 200.2 19.7 87.2 46.1 53.3 50.4 46.5 51.8 61.8 17.4 29.9 38.9 34.4 14.4 21.2 25.0 47.6 10.0 15.3 15.6 9.6 32.1 30.1 38.7 16.4 74.1 15.0 17.6 18.8 31.1 13.8 24.1 24.7 24.1 20.2 19.2 17.9 22.6 187.0 198.7 296.6 53.5 109.4 148.5 115.4 181.3 152.0 117.4 245.8 153.5 537.0 185.8 247.0 182.1 158.4 162.5 148.6 174.3 49.0 173.6 225.5 160.9 253.9 204.0 178.0 133.3 45.5 153.5 245.8 202.8 156.5 255.5 197.9 137.7 157.5 438.7 227.7 159.9 77.0 250.0 134.3 206.4 215.6 817.5 159.1 218.3 176.1 44.0 181.1 213.8 84.5 63.3 79.4 153.1 125.1 191.1 327.3 249.5 188.2 196.4 294.3 160.9 92.1 114.6 211.2 158.4 72.7 182.3 161.8 244.8 105.8 183.1 251.0 157.8 CAP2 ENSG00000112186 "Cyclase associated actin cytoskeleton regulatory protein 2" P40123 6 17393505-17557790 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 577.1;tongue: 313.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.5;Excitatory neurons: 158.1;Inhibitory neurons: 137.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 26.1;basal ganglia: 40.9;cerebral cortex: 87.2;hippocampal formation: 50.2;white matter: 32.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 101.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050530, HPA054147" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA050530: AB_2681159, HPA054147: AB_2682400" "unprognostic (7.27e-2)" "unprognostic (5.71e-3)" "unprognostic (1.63e-2)" "unprognostic (1.55e-1)" "unprognostic (4.86e-1)" "unprognostic (2.23e-2)" "unprognostic (9.94e-2)" "unprognostic (3.58e-2)" "unprognostic (7.72e-2)" "unprognostic (1.65e-1)" "unprognostic (6.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (8.05e-2)" "unprognostic (1.75e-3)" 17.8 11.6 26.1 7.6 40.9 0.0 10.7 0.9 87.2 15.4 2.9 32.6 4.1 28.5 17.8 21.7 16.8 11.4 113.6 50.2 11.1 8.7 4.5 4.7 1.7 3.2 3.8 4.5 4.2 7.5 5.1 8.8 2.7 25.1 9.6 9.1 7.7 30.7 577.1 2.6 8.9 42.7 0.0 3.1 9.8 1.5 9.1 3.1 5.5 313.0 2.3 14.5 6.4 32.3 15.5 24.6 44.4 55.1 0.3 0.1 10.4 52.3 42.7 46.6 43.0 8.1 6.9 0.0 48.9 62.1 60.5 8.2 21.3 20.9 66.8 0.1 7.9 0.0 15.4 26.5 4.3 0.0 0.0 3.5 9.9 23.1 10.3 72.3 2.2 0.0 0.0 0.1 101.6 25.2 0.0 0.0 17.0 0.8 15.6 5.2 59.1 1.1 23.6 6.4 6.1 10.9 19.0 59.2 31.3 82.8 65.0 11.2 0.2 36.6 31.6 1.0 47.6 0.0 0.0 0.2 11.7 0.1 48.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 40.9 0.9 87.2 50.2 11.1 3.2 3.8 2.7 0.0 9.1 32.3 2.0 3.2 1.5 9.8 0.0 1.9 4.3 6.2 5.7 16.4 10.2 8.4 126.5 4.3 5.4 1.8 4.2 16.5 0.0 1.9 3.9 2.7 0.1 13.9 13.7 2.7 6.0 0.0 158.1 0.7 12.2 7.9 0.0 5.8 0.0 22.8 3.9 2.4 2.2 8.4 137.2 1.3 2.0 0.0 2.2 0.0 0.6 0.3 0.0 10.3 0.0 6.3 0.0 16.6 7.2 3.7 1.9 4.9 0.0 1.9 0.0 16.7 33.9 2.2 32.9 25.5 43.4 0.1 3.2 2.1 0.9 37.5 0.3 0.3 1.6 0.6 CAPN6 "CalpM, CANPX, CAPNX" ENSG00000077274 "Calpain 6" Q9Y6Q1 X 111245099-111270483 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 212.7;placenta: 83.1;seminal vesicle: 72.4" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 198.5;Syncytiotrophoblasts: 140.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 25.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HDLM-2: 10.8;NTERA-2: 16.3;SuSa: 14.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 9.6" HPA040259 Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA040259: " "unprognostic (1.27e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-2)" "unprognostic (5.77e-3)" "unprognostic (2.07e-1)" "unprognostic (9.93e-2)" "unprognostic (8.39e-3)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (9.45e-3)" "unprognostic (5.12e-1)" "unprognostic (6.25e-2)" "unprognostic (7.67e-2)" "unprognostic (6.50e-2)" "unprognostic (5.02e-3)" "unprognostic (2.66e-1)" "unprognostic (6.30e-2)" 2.1 0.0 0.0 7.2 0.0 0.0 12.7 0.0 0.0 11.9 0.0 5.6 1.8 22.5 212.7 2.3 3.2 8.4 0.3 0.0 0.0 11.5 0.3 0.5 2.8 0.0 0.0 2.6 7.5 0.1 0.2 83.1 0.0 10.6 8.6 0.0 14.1 72.4 3.0 1.0 1.7 8.2 0.0 1.7 12.9 2.0 0.0 1.8 1.5 9.0 4.7 3.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 16.3 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.1 0.3 0.4 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 1.2 0.0 0.6 2.0 0.3 7.2 0.0 7.3 0.0 39.9 0.1 0.1 3.9 8.3 0.0 18.0 4.3 0.4 0.0 0.0 0.0 0.7 198.5 12.9 6.6 40.1 0.0 0.0 0.0 0.0 7.6 0.0 0.1 1.2 0.0 0.0 0.3 0.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 22.2 0.1 0.4 0.0 0.2 0.0 0.0 0.0 1.0 0.5 0.1 0.1 0.9 0.0 140.5 0.3 0.9 0.5 0.3 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871553-10923075 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 110.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073, HPA069313" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA 19000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB032961: AB_2068446, HPA043561: AB_2678554, HPA048073: AB_2680250, HPA069313: " "unprognostic (9.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "unprognostic (2.69e-2)" "unprognostic (3.13e-2)" "unprognostic (1.66e-3)" "unprognostic (3.76e-2)" "unprognostic (7.81e-2)" "unprognostic (6.18e-2)" "unprognostic (9.31e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (7.88e-6)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (8.37e-4)" 20.3 17.1 24.7 19.6 26.6 22.7 17.6 18.9 34.1 30.6 17.2 28.4 17.3 31.7 7.8 36.7 23.4 14.7 25.4 27.6 23.7 18.8 20.1 16.4 19.8 22.8 21.8 21.9 22.3 11.5 14.8 20.4 22.6 20.2 14.3 6.4 20.2 17.5 110.5 22.6 20.9 21.3 19.9 18.6 20.3 45.4 22.6 10.9 13.4 72.4 15.4 26.3 28.0 26.0 62.5 46.8 64.9 88.3 52.5 71.1 63.2 42.8 75.6 63.9 61.0 73.4 21.8 85.2 52.4 77.4 32.1 58.0 65.4 66.2 40.1 98.4 52.7 26.5 29.1 89.9 44.8 39.3 33.9 49.0 42.4 43.8 52.4 35.9 82.1 67.9 65.8 79.2 38.2 116.7 70.0 34.3 81.4 40.7 74.8 97.5 32.8 100.7 38.9 29.7 47.0 45.1 30.7 36.2 43.6 31.7 38.4 35.3 48.7 75.4 43.2 72.3 54.0 75.0 64.1 77.2 51.1 63.8 35.3 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.1 0.5 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.3 0.1 0.1 24.7 26.6 18.9 34.1 27.6 23.7 22.8 21.8 22.6 19.9 22.6 26.0 12.9 9.6 12.2 7.2 11.6 7.8 5.9 4.1 12.0 36.4 14.0 13.7 1.1 14.3 6.5 9.2 52.1 18.5 6.4 42.3 7.9 13.4 32.7 20.1 30.8 12.7 27.6 30.7 12.9 19.7 33.1 13.8 13.7 25.4 1.3 17.8 12.8 27.8 26.7 45.4 10.6 24.9 4.1 20.0 10.9 23.5 28.3 14.8 5.4 5.6 23.9 8.7 4.1 10.6 5.8 24.8 27.2 19.2 11.7 14.1 22.6 9.2 7.4 21.1 6.6 19.6 13.0 23.8 17.5 25.7 7.0 12.0 6.5 6.6 25.7 11.8 CARS1 CARS ENSG00000110619 "Cysteinyl-tRNA synthetase 1" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 10.3;Cardiomyocytes: 8.8;Cytotrophoblasts: 22.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 22.0;Syncytiotrophoblasts: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 200000 "Cluster 14: Monocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB075734: AB_2665740, CAB075735: AB_2665741, CAB075736: AB_2665742, CAB075737: AB_2665743, HPA002383: AB_1078399, HPA002384: AB_1846033" "unprognostic (9.10e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-3)" "unprognostic (1.43e-1)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (8.00e-2)" "unprognostic (5.51e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (3.46e-1)" 22.1 17.4 8.1 12.0 8.5 7.3 19.9 8.7 21.6 13.6 8.4 21.8 12.0 15.9 7.5 19.2 12.8 10.3 13.3 8.2 9.8 13.7 21.1 17.5 12.7 9.6 9.9 8.9 32.8 9.6 18.6 10.3 10.6 12.7 12.8 5.3 20.6 6.8 31.7 23.8 17.4 16.0 9.7 17.2 23.5 16.8 9.9 14.6 17.3 14.7 17.8 18.1 14.9 11.5 29.2 14.0 17.8 55.6 67.3 61.4 16.2 70.0 78.6 46.7 84.1 34.2 64.7 43.1 20.1 88.2 0.0 68.7 58.3 78.6 64.0 123.7 13.5 24.4 23.7 25.8 161.1 50.9 50.2 102.2 64.1 40.1 46.8 0.0 62.3 103.6 42.2 147.0 47.1 41.9 35.7 0.0 65.2 97.9 25.0 17.2 29.7 54.9 0.0 46.1 39.0 49.7 17.1 48.1 80.1 13.3 0.0 0.1 21.8 19.5 18.2 48.2 0.2 107.8 106.8 27.2 0.1 26.6 40.3 16.3 18.6 13.5 20.9 15.4 17.4 10.9 18.3 18.6 19.4 8.5 9.9 16.0 25.4 23.7 37.9 7.5 27.0 19.2 8.1 8.5 8.7 21.6 8.2 9.8 9.6 9.9 10.6 9.7 9.9 11.5 10.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 22.2 8.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 40.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 32.3 1.4 0.0 0.0 0.0 CASC3 "BTZ, MLN51" ENSG00000108349 "CASC3 exon junction complex subunit" O15234 17 40140318-40172171 "Cancer-related genes, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, Stress response, Translation regulation, Transport" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 239.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024592, HPA050262" Approved Approved "Nuclear membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane" "HPA024592: AB_1846034, HPA050262: AB_2681067" "unprognostic (3.76e-2)" "unprognostic (3.18e-1)" "unprognostic (2.00e-1)" "unprognostic (1.00e-1)" "unprognostic (1.98e-1)" "unprognostic (1.77e-2)" "unprognostic (1.48e-3)" "unprognostic (3.40e-3)" "unprognostic (3.38e-1)" "unprognostic (1.16e-2)" "unprognostic (3.29e-3)" "unprognostic (2.87e-1)" "unprognostic (1.66e-2)" "unprognostic (1.15e-1)" "unprognostic (3.41e-1)" "unprognostic (1.27e-1)" "unprognostic (1.48e-2)" 45.5 27.9 88.0 29.9 96.9 37.2 38.5 79.3 95.1 41.0 62.2 48.2 22.9 49.5 38.2 30.3 46.9 25.0 24.8 77.0 90.4 29.0 20.8 35.4 34.1 94.3 88.4 55.6 33.3 35.0 26.0 30.3 89.3 36.1 31.9 39.0 31.8 47.9 55.4 38.1 32.2 47.7 84.9 34.1 35.3 54.1 94.0 40.1 40.4 43.5 37.6 47.7 33.3 96.6 44.6 44.9 58.5 64.9 46.1 48.2 34.3 45.5 40.6 61.3 52.5 48.3 38.3 81.7 67.2 57.7 50.4 77.8 71.8 48.0 83.5 54.8 58.1 58.6 55.4 50.6 42.0 74.7 39.6 50.2 43.9 59.9 93.6 46.8 77.4 45.8 64.0 61.5 50.8 25.6 110.9 44.3 44.5 39.8 26.0 67.3 74.5 85.9 32.1 39.5 85.4 49.8 63.8 239.4 59.4 91.1 78.2 58.9 50.0 51.7 53.3 48.7 71.0 56.5 56.3 81.1 50.4 40.2 57.1 7.8 9.4 13.1 12.5 11.5 11.1 8.6 9.3 11.5 10.0 8.6 10.5 10.4 35.9 10.2 18.2 5.8 9.1 8.6 88.0 96.9 79.3 95.1 77.0 90.4 94.3 88.4 89.3 84.9 94.0 96.6 32.8 19.2 36.8 31.0 29.5 19.8 22.9 11.3 31.3 40.8 38.5 32.5 26.7 14.3 31.8 23.9 22.9 19.9 38.0 21.4 21.5 17.8 14.8 30.2 38.8 34.0 31.2 23.5 29.0 24.3 21.3 26.9 26.0 31.4 16.4 32.5 23.9 21.9 17.0 30.3 32.8 20.8 18.3 26.4 29.2 24.5 36.1 25.8 35.6 22.5 23.9 23.5 26.8 15.1 34.5 21.0 17.6 29.7 26.5 27.2 17.3 18.1 27.2 38.5 13.1 42.0 40.2 59.4 67.7 28.1 19.9 27.1 30.1 22.7 20.6 24.7 CASP1 "ICE, IL1BC" ENSG00000137752 "Caspase 1" P29466 11 105025443-105035250 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 126.0;lymphoid tissue: 91.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 125.3;Langerhans cells: 120.7;Macrophages: 136.6;monocytes: 185.6;Proximal enterocytes: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 112.7;HBEC3-KT: 53.8;HHSteC: 58.2;U-937: 136.2" "Region enhanced" "Detected in all" "olfactory bulb: 18.4" "Low region specificity" "Detected in all" "CAB002685, HPA003056" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Nucleoplasm "CAB002685: , HPA003056: AB_1846037" "unprognostic (1.21e-3)" "unprognostic (3.02e-1)" "unprognostic (9.47e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (6.67e-2)" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.03e-2)" "unprognostic (2.30e-2)" "unprognostic (3.18e-1)" "unprognostic (5.19e-2)" 20.4 10.5 8.7 59.1 8.8 36.3 21.9 9.3 14.6 11.9 9.8 47.7 124.6 8.7 12.0 27.2 12.3 27.4 12.2 8.5 9.6 13.3 21.6 48.3 52.1 11.2 9.4 11.7 6.4 2.7 5.0 30.0 11.1 13.0 49.7 1.1 20.8 12.5 6.2 30.9 126.0 20.8 10.7 91.0 22.5 2.4 10.7 23.2 7.8 7.3 35.5 35.7 19.4 11.9 1.3 0.3 0.0 5.3 5.8 12.1 1.0 5.7 112.7 14.0 38.5 0.2 0.7 18.7 2.3 6.6 25.7 8.1 0.0 53.8 3.3 12.3 0.0 0.9 0.7 1.3 58.2 22.1 0.2 20.9 37.4 11.4 30.3 36.2 6.1 0.3 0.2 0.0 3.4 0.0 0.6 30.7 0.0 0.1 0.3 18.1 0.4 14.9 0.3 8.9 0.4 0.4 16.9 1.1 26.2 0.1 1.2 50.1 7.2 12.8 0.6 1.2 1.6 0.1 5.4 0.1 8.1 136.2 2.7 83.8 246.1 134.9 132.9 359.9 178.5 40.2 92.7 115.8 220.2 35.5 50.2 82.7 220.0 63.0 383.0 7.7 129.0 213.3 8.7 8.8 9.3 14.6 8.5 9.6 11.2 9.4 11.1 10.7 10.7 11.9 26.3 19.2 30.0 0.0 27.2 26.0 42.5 91.5 14.2 0.1 5.8 23.0 2.9 8.6 37.7 11.0 0.0 2.1 34.1 33.1 1.9 23.3 0.2 5.8 2.5 24.0 6.0 10.3 0.2 12.9 1.3 17.8 11.7 3.4 15.8 0.2 22.9 3.1 96.5 0.0 0.0 50.6 14.2 125.3 120.7 1.3 3.4 136.6 5.4 12.2 185.6 0.1 64.9 0.0 0.1 5.3 73.4 3.4 20.0 8.7 116.0 2.2 28.4 0.2 0.0 1.0 8.1 0.0 0.1 17.9 22.3 1.1 58.4 3.3 90.5 43.6 CASP10 "FLICE-2, MCH4" ENSG00000003400 "Caspase 10" Q92851 2 201182898-201229406 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 71.3;NK-cells: 44.3;Paneth cells: 44.5;Plasma cells: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 25.3" "Low region specificity" "Detected in all" "CAB003780, HPA017059" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "CAB003780: AB_289592, HPA017059: AB_1846040" "unprognostic (4.01e-2)" "unprognostic (8.24e-2)" "unprognostic (4.80e-1)" "unprognostic (1.28e-3)" "unprognostic (4.74e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.05e-7)" "unprognostic (3.23e-2)" "unprognostic (2.19e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" 8.8 2.4 5.7 9.2 5.5 19.5 6.5 4.5 5.8 4.0 4.4 13.2 21.8 3.3 6.2 8.8 5.4 7.4 6.7 4.7 5.1 8.1 6.2 11.5 8.9 6.0 5.0 1.6 4.8 2.3 1.3 9.6 5.8 3.9 13.4 1.3 5.4 3.1 4.9 5.7 18.4 5.1 5.6 22.6 10.2 1.2 7.3 8.7 5.3 2.8 10.4 9.0 5.1 5.4 4.4 3.5 0.3 0.4 0.1 0.3 7.5 0.7 4.6 0.4 1.8 4.6 9.8 0.5 7.0 2.5 1.7 2.9 0.2 2.3 1.3 2.1 4.8 12.2 4.0 15.1 1.6 8.3 12.7 0.5 2.0 5.3 0.4 0.3 25.3 5.1 14.9 17.4 0.4 0.3 15.9 7.8 0.6 6.0 2.4 8.8 0.5 18.4 8.7 6.2 0.2 0.1 4.1 0.2 1.9 3.0 0.2 7.8 10.0 0.4 0.8 3.4 0.2 18.7 12.1 0.5 4.5 6.3 0.2 5.9 11.7 0.7 6.4 16.5 5.6 8.2 5.2 3.6 6.5 7.7 7.2 6.4 2.1 8.5 19.3 6.6 1.2 7.2 5.7 5.5 4.5 5.8 4.7 5.1 6.0 5.0 5.8 5.6 7.3 5.4 20.7 19.2 10.0 0.3 15.8 6.0 2.7 10.6 5.2 0.0 1.3 0.9 1.8 8.6 9.4 9.2 0.0 1.1 20.5 71.3 1.9 16.2 1.2 7.7 7.4 29.7 2.4 14.9 0.3 10.4 0.7 4.2 26.5 12.0 7.6 0.8 26.4 7.1 9.4 0.0 0.5 21.6 4.1 26.6 17.5 0.0 0.6 16.2 7.2 33.7 22.0 0.5 44.3 0.0 0.9 8.6 44.5 0.0 49.7 2.5 26.1 8.7 24.4 0.4 0.0 2.9 2.2 0.1 0.1 6.6 4.5 0.4 12.9 4.1 16.4 10.3 CASP2 "ICH1, MGC2181, NEDD2, PPP1R57" ENSG00000106144 "Caspase 2" P42575 7 143288215-143307696 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012175, HPA050678" Approved Approved Nucleoplasm NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "CAB012175: , HPA050678: AB_2681214" "unprognostic (6.96e-2)" "prognostic favorable (7.38e-4)" "unprognostic (2.74e-2)" "unprognostic (7.51e-2)" "unprognostic (4.24e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (1.74e-2)" "unprognostic (1.34e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.91e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.66e-3)" "unprognostic (9.48e-2)" "unprognostic (1.19e-1)" "unprognostic (1.64e-1)" 10.3 6.6 6.0 13.9 6.7 40.2 10.5 7.8 6.7 11.8 6.7 11.1 10.7 10.2 9.6 15.3 10.3 7.0 8.4 5.9 6.2 9.1 6.4 10.4 22.0 7.2 6.4 9.3 8.4 11.1 5.3 12.4 7.7 7.6 12.7 7.7 11.9 6.3 3.9 17.4 15.4 9.4 5.9 19.0 9.6 9.1 6.9 27.5 8.8 5.0 27.1 7.5 11.2 10.0 27.5 25.4 28.8 51.0 15.1 17.5 15.4 27.7 13.0 25.4 27.8 26.0 31.3 52.0 25.9 18.4 19.4 27.3 29.4 22.6 34.0 45.8 22.5 31.2 40.4 18.3 8.4 60.7 37.4 13.0 18.1 31.0 11.0 11.3 22.0 41.3 26.3 32.6 27.5 27.5 109.1 64.4 36.5 27.4 26.3 79.1 14.6 32.6 15.1 23.3 31.5 34.2 54.8 24.3 17.3 19.6 26.3 23.4 24.1 22.5 15.5 40.7 28.1 27.0 28.5 59.4 24.9 72.6 41.1 69.2 17.9 17.2 24.5 21.7 24.2 25.7 33.3 25.3 17.3 28.8 24.3 28.3 21.7 24.2 34.1 21.1 38.9 15.3 6.0 6.7 7.8 6.7 5.9 6.2 7.2 6.4 7.7 5.9 6.9 10.0 14.1 9.6 8.3 4.2 17.4 15.2 7.0 9.4 6.2 4.8 19.0 13.5 6.2 17.2 7.0 7.3 8.4 20.0 19.3 8.7 3.9 8.1 36.6 10.8 17.9 16.4 10.7 9.7 11.2 7.7 14.6 9.3 8.2 20.1 10.1 22.7 18.2 7.2 10.1 6.7 8.8 11.5 0.0 16.9 23.3 51.0 11.8 12.2 21.4 4.7 20.8 4.4 13.4 4.5 22.4 9.4 5.9 8.2 13.0 5.8 9.1 4.2 4.9 15.4 0.0 8.3 10.9 13.7 25.9 16.1 13.8 5.7 16.7 9.3 15.5 7.0 CASP3 "apopain, CPP32, CPP32B, Yama" ENSG00000164305 "Caspase 3" P42574 4 184627696-184649509 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 571.0;eosinophil: 408.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 571.0" "Cell line enhanced" "Detected in all" "Karpas-707: 259.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000091, HPA002643, CAB008381" Enhanced Approved Nucleoplasm,Mitochondria NA NA 94000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria Nucleoplasm "CAB000091: , CAB008381: AB_590737, HPA002643: AB_1846048" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "prognostic favorable (2.24e-4)" "unprognostic (2.29e-3)" "unprognostic (3.58e-2)" "unprognostic (9.57e-3)" "unprognostic (5.86e-2)" "unprognostic (3.56e-2)" "unprognostic (1.12e-2)" "unprognostic (1.70e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.41e-2)" "unprognostic (5.74e-3)" "unprognostic (1.30e-1)" "unprognostic (4.05e-3)" 16.3 12.1 11.3 26.6 10.9 32.8 16.3 18.6 11.4 12.7 10.0 34.2 54.1 12.7 12.9 27.7 9.2 19.9 14.7 10.8 12.2 8.5 22.0 12.8 43.4 10.8 11.5 8.9 13.4 9.0 8.8 26.1 11.4 11.3 33.9 12.7 13.2 10.6 13.9 16.1 41.8 15.3 11.6 23.0 31.2 9.3 11.3 39.0 10.6 14.1 41.9 24.4 12.0 13.0 31.0 16.7 65.3 31.6 39.4 52.2 37.6 90.2 67.7 61.9 35.4 30.7 25.2 42.4 13.9 44.1 29.2 25.5 52.1 32.1 69.7 109.9 28.7 68.2 12.9 71.4 47.3 55.9 62.3 71.7 38.3 39.3 31.4 44.4 77.6 43.1 57.2 259.8 64.5 13.2 89.1 51.8 65.1 33.7 20.9 63.6 30.8 41.2 52.9 49.3 37.1 40.5 39.1 35.1 52.1 64.3 19.2 35.9 54.1 28.2 25.9 21.1 42.4 118.9 121.6 29.2 34.2 38.5 40.9 571.0 26.1 408.6 32.1 43.3 34.4 26.0 29.5 46.3 33.3 18.6 22.2 32.8 35.6 62.0 71.0 26.5 64.1 47.5 11.3 10.9 18.6 11.4 10.8 12.2 10.8 11.5 11.4 11.6 11.3 13.0 28.6 19.2 15.8 26.4 32.3 48.7 22.2 34.1 35.9 18.6 21.7 17.0 17.5 5.7 36.3 12.9 0.0 46.9 54.8 37.4 13.7 18.4 9.6 24.9 17.1 26.6 18.0 62.3 9.6 23.7 33.6 19.5 24.5 24.9 17.7 24.8 21.0 15.3 23.9 13.5 12.6 37.6 44.7 27.0 17.4 4.0 7.5 33.3 30.2 13.1 41.5 15.4 37.0 11.1 18.4 25.0 18.8 7.5 118.6 20.1 26.6 8.4 30.4 11.3 13.1 19.0 20.8 7.9 16.4 34.6 28.6 51.4 43.8 23.1 24.4 36.7 CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969366 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavorable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" 45.7 21.7 7.0 69.4 7.2 48.5 44.4 7.4 12.4 26.4 8.6 27.6 62.4 18.4 33.1 47.7 34.9 50.1 17.8 7.5 8.0 33.3 54.1 61.3 80.2 9.7 8.1 43.2 52.5 4.7 11.0 70.2 8.7 21.7 30.7 2.0 55.2 15.5 7.5 46.7 58.8 32.2 8.3 71.1 42.4 4.9 9.0 57.2 15.6 18.1 82.1 76.5 30.5 8.7 33.8 9.5 0.0 12.9 58.2 140.4 27.8 68.0 103.2 80.5 117.0 22.4 128.5 22.3 123.1 71.5 110.4 52.7 0.0 94.3 78.8 22.4 0.4 53.1 7.4 55.8 158.2 48.5 19.2 122.6 127.0 97.9 144.4 104.7 143.8 0.5 1.3 0.0 64.4 2.8 26.1 46.7 0.0 71.6 28.2 21.4 21.5 14.2 64.9 46.2 0.6 0.4 60.8 31.6 49.3 0.7 11.9 62.5 93.2 84.4 30.4 80.8 40.5 0.0 0.0 0.3 42.2 105.5 63.4 136.4 292.0 50.6 208.9 312.9 224.8 141.9 155.6 193.9 205.5 144.4 93.4 138.5 667.2 226.2 255.4 35.4 257.9 410.9 7.0 7.2 7.4 12.4 7.5 8.0 9.7 8.1 8.7 8.3 9.0 8.7 78.1 60.9 60.8 0.3 87.4 55.8 63.3 130.1 21.1 0.0 40.8 48.4 5.6 47.1 107.0 22.0 0.0 129.1 80.4 12.4 15.6 157.5 0.6 35.9 27.7 73.0 20.9 12.4 0.0 189.9 103.0 53.6 33.1 45.7 34.8 32.6 82.1 34.7 116.7 0.0 0.2 37.8 73.2 168.0 81.2 2.1 29.2 105.2 30.2 23.4 141.5 1.9 177.1 1.5 0.2 148.5 8.6 20.7 50.5 31.1 85.4 41.1 86.1 0.4 6.6 38.1 34.2 0.2 0.5 25.8 45.9 115.9 102.1 36.8 32.9 80.0 CASP5 ICE(rel)III ENSG00000137757 "Caspase 5" P51878 11 104994235-105023168 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.0;intestine: 16.8;lymphoid tissue: 14.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 31.4;Paneth cells: 18.7;Proximal enterocytes: 17.2;Undifferentiated cells: 7.3" "Group enriched" "Detected in some" 7 "colorectal cancer: 3.9;stomach cancer: 1.3" "Region enhanced" "Detected in some" "cerebral cortex: 5.0" "Group enriched" "Detected in some" 13 "intermediate monocyte: 18.1;neutrophil: 13.0;non-classical monocyte: 41.2" "Group enriched" "Detected in many" 15 "granulocytes: 13.0;monocytes: 41.2" "Cell line enriched" "Detected in single" 6 "HHSteC: 3.7" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (4.30e-2)" "unprognostic (8.86e-2)" "unprognostic (1.07e-1)" "unprognostic (4.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.22e-2)" "unprognostic (9.90e-2)" "unprognostic (8.29e-3)" "unprognostic (1.47e-1)" "unprognostic (4.38e-3)" "unprognostic (7.39e-3)" "unprognostic (3.25e-1)" "unprognostic (1.82e-9)" "unprognostic (7.30e-2)" "unprognostic (2.67e-3)" "unprognostic (1.87e-1)" "unprognostic (1.50e-1)" 0.7 0.1 0.5 14.6 0.6 0.2 0.1 0.5 5.0 0.2 0.6 15.6 10.0 0.1 0.2 0.1 0.2 0.4 0.1 0.5 0.5 0.2 0.2 1.6 0.9 0.7 0.8 0.1 0.0 0.0 0.1 0.9 1.5 0.1 12.9 0.0 0.1 0.1 0.0 0.0 16.8 1.8 0.6 2.7 0.1 0.3 0.8 0.1 0.1 0.4 0.3 2.2 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.1 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 18.1 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.1 13.0 0.0 41.2 0.5 0.0 1.4 0.5 0.6 0.5 5.0 0.5 0.5 0.7 0.8 1.5 0.6 0.8 0.9 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.4 0.0 2.3 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 5.3 0.0 4.7 0.4 0.7 0.0 4.8 0.0 1.9 2.4 0.0 0.0 0.0 0.1 0.1 18.7 0.0 0.0 0.0 17.2 0.0 0.8 0.0 0.0 0.2 0.1 0.5 0.7 0.0 0.0 0.0 0.3 0.0 7.3 0.1 CASP6 MCH2 ENSG00000138794 "Caspase 6" P55212 4 109688622-109703583 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 40.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003775, HPA011337, HPA024303" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol Nucleoplasm "CAB003775: AB_562064, HPA011337: AB_1846053, HPA024303: AB_1846052" "unprognostic (1.07e-1)" "unprognostic (1.91e-1)" "prognostic favorable (2.64e-5)" "unprognostic (1.45e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "unprognostic (3.03e-3)" "unprognostic (9.87e-2)" "unprognostic (2.73e-2)" "unprognostic (2.59e-3)" "unprognostic (1.15e-2)" "unprognostic (6.78e-2)" "unprognostic (2.44e-1)" "unprognostic (8.74e-3)" "unprognostic (2.18e-1)" "unprognostic (2.41e-1)" "prognostic favorable (9.93e-4)" 6.5 6.7 3.9 8.4 4.0 10.8 10.5 4.3 5.4 7.6 4.0 35.3 40.8 7.7 5.1 7.4 7.6 9.3 5.6 3.8 4.0 11.5 18.1 7.8 9.6 3.7 3.7 8.3 13.3 4.8 4.2 4.8 3.8 9.1 31.5 3.0 8.6 6.5 3.3 10.7 36.8 7.4 3.8 8.0 15.8 1.8 3.7 11.5 8.5 2.4 7.7 8.1 7.0 4.3 26.6 8.4 16.5 14.8 11.0 11.2 24.3 15.3 9.2 12.4 13.4 13.8 50.3 2.7 16.4 14.7 17.3 12.1 19.7 21.8 8.4 43.5 13.0 22.8 7.1 12.9 9.4 23.5 15.7 12.6 15.1 12.4 2.8 17.1 22.9 30.1 29.9 76.1 19.2 13.7 62.0 14.4 12.7 17.1 16.1 20.5 10.8 13.3 39.6 24.8 17.2 13.2 15.0 25.7 8.8 19.6 11.0 8.0 20.3 12.8 14.6 6.6 16.7 11.4 23.0 2.8 17.1 26.9 7.1 16.3 6.9 8.9 6.3 6.9 7.0 6.1 23.8 12.3 8.8 8.6 28.0 16.1 1.4 7.5 11.2 11.6 24.8 9.4 3.9 4.0 4.3 5.4 3.8 4.0 3.7 3.7 3.8 3.8 3.7 4.3 10.5 16.0 14.6 5.2 7.7 10.8 10.2 26.7 12.0 6.9 23.6 16.0 4.1 28.6 23.2 20.2 6.2 20.9 7.6 54.0 9.8 40.8 2.6 19.8 9.5 12.2 59.2 19.7 6.4 46.4 41.1 13.4 18.3 23.3 10.1 112.3 9.7 20.4 19.8 0.0 7.3 53.9 32.6 8.7 9.3 1.7 12.8 14.5 1.8 2.8 17.9 16.0 6.2 5.5 5.8 45.9 52.5 9.8 8.8 7.4 71.7 35.7 18.6 1.3 6.6 7.6 12.3 1.9 8.6 10.8 11.6 5.7 17.5 12.4 74.2 8.0 CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.1;Paneth cells: 113.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB025563 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB025563: " "prognostic favorable (2.11e-4)" "unprognostic (3.18e-2)" "unprognostic (2.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-3)" "unprognostic (3.96e-1)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "prognostic unfavorable (5.90e-4)" "unprognostic (5.45e-3)" "unprognostic (2.62e-1)" "unprognostic (2.86e-1)" "unprognostic (4.33e-3)" 21.0 10.3 11.8 26.2 12.2 8.4 18.6 11.5 20.4 18.4 12.8 75.1 65.3 16.3 10.5 15.4 17.9 16.8 11.3 11.8 12.0 19.6 23.6 24.9 16.9 12.3 12.5 16.2 22.4 10.4 7.0 20.9 11.9 21.3 58.2 6.8 34.1 12.3 13.8 17.4 68.1 18.5 11.4 17.5 45.5 6.8 12.8 19.8 10.2 14.5 18.4 31.6 16.1 12.8 28.9 29.4 24.1 13.0 43.4 37.5 16.7 32.9 49.9 56.1 69.7 22.4 51.0 30.1 19.0 29.8 21.1 24.8 30.4 24.2 39.5 46.9 41.0 19.6 22.0 38.0 28.9 20.9 24.7 24.5 15.9 32.0 13.3 25.0 75.4 28.2 5.3 39.8 21.1 38.2 51.1 16.0 4.4 31.7 17.3 51.7 98.0 18.1 44.8 21.4 1.9 14.4 24.9 35.5 17.6 23.1 43.1 18.4 37.8 12.8 24.1 13.5 27.7 30.7 20.1 0.8 13.1 38.7 14.3 22.9 14.7 11.7 11.1 21.3 9.5 11.5 9.2 14.1 10.4 9.2 7.1 9.7 2.6 7.4 18.5 1.4 14.0 9.8 11.8 12.2 11.5 20.4 11.8 12.0 12.3 12.5 11.9 11.4 12.8 12.8 36.3 9.6 12.3 27.4 13.8 19.8 21.2 26.0 13.1 0.6 15.8 9.9 2.5 11.5 26.2 22.0 0.0 12.4 10.3 229.1 11.7 46.1 0.3 21.0 22.9 23.8 9.6 4.0 1.6 39.0 25.5 16.2 30.1 13.5 12.7 10.9 17.2 15.6 17.0 0.0 1.1 81.1 28.5 12.8 6.9 0.6 9.6 18.4 7.2 10.3 68.9 7.9 13.4 1.0 0.8 37.2 113.4 4.1 21.5 42.6 88.0 25.9 42.8 1.7 19.7 12.3 16.3 2.9 28.2 13.3 14.8 10.9 15.7 5.2 50.7 39.0 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 66.6" "Cell type enhanced" "Detected in many" "dendritic cells: 107.4;NK-cells: 132.8;Plasma cells: 73.4;T-cells: 86.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol No No "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: AB_2667535" "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favorable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 11.5 10.2 1.7 28.6 2.0 66.6 13.9 1.3 2.1 9.6 4.2 16.1 20.5 8.5 13.2 12.9 14.1 13.2 5.2 2.1 1.8 10.7 14.1 19.6 37.7 3.4 3.0 7.7 7.8 2.9 3.4 9.9 2.7 6.9 17.6 4.6 8.4 7.3 3.3 12.1 26.0 9.9 2.4 37.1 15.9 4.3 2.6 24.4 7.9 3.0 29.7 18.0 8.6 2.4 33.6 26.6 7.7 22.2 20.7 29.7 12.0 13.8 13.2 16.0 26.2 36.1 54.9 3.7 29.6 10.7 28.7 16.2 17.2 16.1 31.3 21.1 15.4 31.0 21.9 35.1 17.1 25.6 33.8 25.9 38.0 30.1 23.9 13.4 15.1 26.9 28.6 69.1 14.7 13.1 32.1 25.9 12.6 17.5 23.7 24.7 15.9 55.4 30.8 35.3 2.3 1.1 17.9 29.8 18.0 7.0 8.0 19.1 19.6 17.3 18.0 9.0 10.9 63.1 30.2 21.2 25.3 33.1 16.6 76.1 39.5 77.1 70.7 51.2 66.0 40.9 57.8 75.9 41.6 24.0 37.0 47.2 153.6 70.6 51.5 18.6 75.0 40.6 1.7 2.0 1.3 2.1 2.1 1.8 3.4 3.0 2.7 2.4 2.6 2.4 8.5 25.6 26.7 0.7 50.0 7.5 13.0 6.1 10.2 2.1 12.9 9.3 2.5 10.0 13.0 5.5 10.4 8.5 107.4 37.0 15.6 12.3 5.9 25.6 8.1 10.1 4.2 10.5 2.5 8.4 12.1 9.5 19.4 27.2 24.6 10.4 5.3 11.7 11.9 0.0 1.3 15.2 4.1 25.3 15.7 1.9 2.5 25.0 7.2 10.3 35.6 0.2 132.8 1.0 0.5 11.2 30.1 0.7 73.4 9.7 22.3 23.6 14.2 0.4 0.0 4.5 3.7 0.8 0.4 13.1 7.7 3.4 86.9 10.6 17.4 12.7 CASP9 "APAF-3, ICE-LAP6, MCH6, PPP1R56" ENSG00000132906 "Caspase 9" P55211 1 15490832-15526534 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001473, CAB004348, HPA046488" Approved Approved Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB004348: AB_673489, HPA001473: AB_1078401, HPA046488: AB_2679670" "prognostic favorable (5.91e-4)" "unprognostic (2.42e-1)" "unprognostic (8.94e-3)" "unprognostic (7.84e-2)" "unprognostic (1.93e-2)" "unprognostic (8.54e-3)" "unprognostic (1.90e-3)" "unprognostic (6.75e-2)" "unprognostic (2.58e-1)" "unprognostic (1.29e-1)" "unprognostic (9.09e-2)" "unprognostic (1.98e-1)" "unprognostic (1.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.21e-2)" "unprognostic (5.48e-2)" "prognostic favorable (1.67e-5)" 12.0 50.8 14.1 7.0 14.5 11.5 8.9 16.1 18.8 19.3 13.3 11.8 6.4 14.4 12.5 14.1 22.5 9.4 16.4 14.2 13.0 20.7 14.8 10.8 6.9 14.8 14.2 57.6 37.8 12.0 32.4 7.1 14.1 19.2 5.3 12.3 8.9 9.8 12.7 5.5 11.0 6.6 13.6 10.6 12.4 25.9 14.6 8.7 25.9 9.4 7.9 12.9 12.8 17.1 10.4 17.8 4.6 8.9 11.0 5.4 5.3 7.5 9.9 11.1 12.7 12.5 10.1 13.4 16.2 7.5 13.1 4.2 10.5 8.2 11.7 5.9 11.6 9.8 32.8 10.8 10.8 10.6 11.5 9.7 11.5 15.3 3.8 8.3 8.7 13.3 20.4 13.4 5.8 5.2 3.3 8.6 5.9 11.3 8.2 7.4 13.4 16.4 12.3 6.7 4.4 9.0 9.6 1.8 15.6 12.1 5.7 7.9 4.8 13.8 5.8 15.6 5.1 13.3 21.5 16.3 8.9 9.9 5.0 54.2 24.7 54.8 11.0 17.4 8.2 21.3 6.6 7.6 25.1 30.0 3.1 4.8 36.3 29.3 18.9 11.4 6.9 15.0 14.1 14.5 16.1 18.8 14.2 13.0 14.8 14.2 14.1 13.6 14.6 17.1 2.8 3.2 3.7 18.3 17.1 2.9 8.2 5.0 4.6 3.2 7.0 4.7 9.3 11.5 7.3 18.4 6.2 17.0 8.0 7.0 1.9 7.5 12.6 10.9 5.2 3.3 3.0 5.7 7.9 9.1 10.8 5.6 12.8 7.6 1.3 5.7 4.2 4.7 9.5 5.0 9.9 6.3 6.1 4.8 12.9 5.5 2.1 12.9 0.0 6.5 4.8 7.5 10.3 9.5 8.8 8.4 7.3 3.8 9.9 4.0 9.8 7.2 8.9 6.3 0.0 5.3 9.7 16.4 7.1 6.0 2.4 35.7 6.4 7.9 5.6 7.4 CAST ENSG00000153113 Calpastatin P20810 5 96525267-96779595 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 858.4;Early spermatids: 979.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009491, HPA036881, HPA036882, HPA075906" Enhanced Enhanced "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 17000000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "CAB009491: AB_2259755, HPA036881: AB_2675359, HPA036882: AB_2675360, HPA075906: " "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.91e-2)" "unprognostic (4.68e-2)" "unprognostic (1.45e-1)" "unprognostic (3.79e-1)" "unprognostic (4.53e-3)" "unprognostic (1.94e-2)" "unprognostic (6.11e-3)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.66e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.16e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (4.98e-4)" 144.4 68.4 32.3 86.1 36.3 119.1 104.1 35.0 40.8 147.2 55.5 160.1 120.5 83.8 49.0 342.8 79.7 78.7 303.7 30.7 42.2 82.0 116.8 112.1 52.9 46.7 43.2 83.1 56.1 111.7 51.2 116.1 44.4 100.2 148.2 17.1 130.0 78.7 317.3 157.4 137.2 92.2 38.3 64.1 100.5 98.8 39.1 43.1 97.9 166.4 104.3 129.4 216.4 41.7 300.3 239.7 42.6 112.1 240.1 390.1 145.4 220.9 288.8 169.1 215.8 60.4 189.6 44.1 189.8 286.1 263.1 465.6 81.3 283.5 202.8 292.4 78.5 65.9 251.0 71.1 172.9 38.9 100.1 201.8 254.8 239.6 375.0 222.9 194.8 33.5 51.7 144.5 196.4 98.0 17.9 2.0 35.4 85.0 89.9 18.2 141.9 78.3 327.1 114.1 179.6 45.0 222.6 118.2 142.5 94.0 77.4 39.5 263.9 239.0 94.6 154.9 211.4 51.2 140.4 22.1 264.7 21.8 67.5 10.5 156.6 24.1 75.6 85.3 74.1 79.4 68.2 76.9 107.5 79.1 34.8 45.7 38.2 61.6 109.8 28.8 79.2 108.1 32.3 36.3 35.0 40.8 30.7 42.2 46.7 43.2 44.4 38.3 39.1 41.7 251.6 403.8 221.4 58.1 153.8 239.6 439.8 223.6 169.0 39.4 133.6 84.5 858.4 163.0 277.0 108.5 18.8 181.2 227.1 484.0 133.1 263.6 979.7 348.0 213.4 188.5 142.1 229.3 60.2 249.7 96.2 259.0 153.4 327.8 177.1 71.8 138.8 169.3 113.7 13.5 53.0 253.9 103.7 209.4 259.1 414.4 172.1 243.8 131.6 63.7 354.4 36.9 293.6 33.2 70.2 325.1 346.8 146.3 126.3 314.7 302.9 152.3 379.0 19.5 92.1 267.8 175.0 23.6 17.9 348.9 251.7 140.8 207.7 69.8 221.2 548.5 CAT ENSG00000121691 Catalase P04040 11 34438934-34472060 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Mitogen, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1217.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 722.4;Hepatocytes: 443.4;Proximal tubular cells: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 13 "eosinophil: 4736.8" "Lineage enriched" "Detected in all" 13 "granulocytes: 4736.8" "Cell line enhanced" "Detected in many" "HL-60: 391.4;THP-1: 321.2;U-937: 265.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001515, HPA051282, HPA055838" Enhanced Enhanced Vesicles NA NA 760000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "CAB001515: AB_384710, HPA051282: AB_2681419, HPA055838: AB_2682937" "unprognostic (3.62e-2)" "unprognostic (2.72e-1)" "unprognostic (3.59e-3)" "unprognostic (5.43e-2)" "unprognostic (4.44e-2)" "unprognostic (5.80e-3)" "prognostic favorable (9.67e-4)" "unprognostic (9.95e-3)" "unprognostic (3.22e-1)" "unprognostic (7.23e-2)" "unprognostic (3.34e-2)" "unprognostic (9.77e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.01e-1)" "unprognostic (7.31e-2)" "unprognostic (4.77e-2)" "unprognostic (6.59e-3)" 281.3 115.1 27.1 52.1 29.6 407.7 123.6 27.9 35.5 82.0 39.4 82.6 145.1 53.1 34.8 40.1 86.8 59.8 58.1 26.6 29.4 296.6 1217.3 163.2 58.4 35.2 29.4 46.7 86.3 43.2 13.6 78.0 34.3 66.8 71.3 9.8 83.7 64.0 103.8 70.6 136.3 59.4 29.6 78.6 74.1 11.4 29.5 74.9 122.6 136.6 56.7 105.8 39.9 40.8 31.7 34.3 24.5 38.9 233.2 100.6 52.3 39.3 49.8 43.3 47.1 19.7 30.9 78.3 37.5 79.2 63.9 73.9 42.3 42.9 47.3 68.8 38.8 65.6 34.0 113.7 27.6 391.4 31.1 54.5 29.3 13.2 5.1 59.9 53.2 46.2 139.3 31.3 55.1 30.2 81.1 77.4 0.1 148.7 82.6 56.5 117.9 64.9 120.2 117.2 13.1 19.8 44.5 70.6 60.0 0.0 101.4 321.2 38.3 25.9 24.9 65.4 23.8 25.0 15.2 16.8 51.3 265.6 19.3 256.5 324.7 4736.8 54.4 265.1 64.6 133.9 63.7 61.0 353.5 124.1 61.7 66.7 290.2 105.7 298.5 235.8 92.7 397.9 27.1 29.6 27.9 35.5 26.6 29.4 35.2 29.4 34.3 29.6 29.5 40.8 196.9 227.6 275.9 41.1 53.8 28.9 93.7 44.9 27.9 13.5 42.6 36.1 44.9 82.9 66.9 73.5 27.1 96.8 92.0 59.4 225.0 36.0 2.7 72.2 41.4 43.8 48.0 722.4 12.6 26.2 30.0 53.1 54.6 29.3 24.0 38.7 57.1 443.4 138.5 0.0 1.2 56.9 91.6 125.5 95.8 6.2 78.3 93.9 26.6 16.9 253.4 19.5 28.8 22.6 45.6 15.3 44.8 77.5 25.4 37.0 151.6 333.2 96.9 19.4 78.9 46.6 68.0 6.3 11.3 24.4 27.1 40.5 37.7 57.7 95.6 97.5 CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2160.5;Alveolar cells type 1: 3557.7;Basal keratinocytes: 1375.3;Endothelial cells: 1024.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 2140.5;BJ hTERT+: 2371.6;HBEC3-KT: 2333.7;LHCN-M2: 2372.1;U-138 MG: 1894.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 122.1" "CAB003791, HPA049326" Enhanced Supported "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB003791: AB_562068, HPA049326: AB_2680714" "unprognostic (5.98e-2)" "unprognostic (1.35e-3)" "unprognostic (3.35e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-3)" "unprognostic (2.35e-3)" "unprognostic (8.07e-2)" "prognostic unfavorable (7.17e-5)" "unprognostic (1.31e-1)" "unprognostic (2.25e-1)" "unprognostic (1.79e-3)" "unprognostic (7.92e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.65e-3)" "unprognostic (2.72e-1)" "unprognostic (7.40e-2)" "unprognostic (6.14e-3)" 621.1 17.4 12.7 44.7 15.3 0.6 284.5 14.3 21.6 267.0 11.8 298.8 32.3 190.9 72.5 135.1 152.5 148.2 276.5 12.2 13.9 18.4 26.6 592.0 30.3 15.1 13.4 137.4 24.6 21.4 6.8 449.2 14.6 110.3 93.6 31.4 58.0 175.5 102.9 104.9 89.4 274.2 14.3 199.1 120.8 25.8 16.1 25.2 168.4 184.6 20.3 202.0 124.1 16.2 458.7 344.3 9.5 3.7 1406.6 2140.5 20.6 1055.8 2371.6 566.0 591.2 3.0 652.4 0.1 365.8 1228.5 494.8 828.2 2.2 2333.7 840.3 36.0 19.5 0.4 128.7 0.3 196.9 0.1 2.1 736.9 481.6 805.7 536.0 539.0 1749.9 0.2 0.3 23.4 2372.1 45.2 0.5 0.8 33.7 1.2 173.9 5.2 25.2 251.0 317.0 2.0 1.0 0.6 328.3 20.1 52.3 137.8 1.6 3.9 1349.3 1894.8 212.4 730.6 298.9 96.8 15.8 1.9 758.4 0.9 701.0 14.6 0.0 0.0 0.0 0.0 0.0 5.1 0.1 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 12.7 15.3 14.3 21.6 12.2 13.9 15.1 13.4 14.6 14.3 16.1 16.2 2160.5 3557.7 123.0 0.0 15.8 1375.3 392.0 534.8 316.4 8.3 17.9 190.8 286.6 107.2 342.0 7.3 2.1 64.3 7.0 0.3 5.9 76.8 2.6 17.5 102.3 1024.0 1.8 16.0 0.4 0.7 449.5 326.8 1.5 21.3 13.9 6.3 450.5 5.2 15.0 0.0 0.5 7.0 20.3 11.0 187.1 13.4 377.2 10.7 439.4 19.7 3.7 249.0 0.0 1.0 1.3 43.1 0.1 565.4 56.2 512.7 0.7 0.3 30.6 7.7 558.8 152.4 751.4 2.1 5.7 39.4 610.9 117.0 16.7 59.7 2.4 93.3 CBFA2T3 "ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4" ENSG00000129993 "CBFA2/RUNX1 partner transcriptional co-repressor 3" O75081 16 88874858-88977207 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;lymphoid tissue: 29.5" "Cell type enhanced" "Detected in many" "Adipocytes: 24.8;B-cells: 26.2;dendritic cells: 25.7;Erythroid cells: 21.0;Intestinal goblet cells: 19.2;Langerhans cells: 23.3;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "cerebellum: 35.8" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 64.2;K-562: 114.9;MCF7: 52.3;MOLT-4: 58.0;NB-4: 70.1;REH: 113.6;T-47d: 50.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059931, HPA062423, HPA065890" Approved Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA059931: AB_2684168, HPA062423: AB_2684758, HPA065890: AB_2685575" "unprognostic (2.47e-1)" "unprognostic (2.03e-2)" "unprognostic (9.24e-3)" "unprognostic (2.62e-1)" "unprognostic (1.98e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.13e-3)" "unprognostic (1.69e-2)" "unprognostic (1.25e-1)" "unprognostic (2.10e-1)" "unprognostic (7.30e-3)" "unprognostic (2.38e-1)" "unprognostic (7.04e-5)" "unprognostic (2.18e-1)" "unprognostic (4.08e-2)" "unprognostic (4.62e-2)" "unprognostic (9.35e-3)" 9.2 2.3 3.6 6.8 4.7 7.7 7.7 35.8 8.4 3.9 0.0 4.9 3.2 5.0 0.7 2.4 3.7 1.7 17.0 5.7 0.0 1.2 4.3 11.3 8.8 0.6 0.9 1.0 27.3 0.7 4.2 3.1 1.7 6.4 1.0 0.8 4.8 0.8 14.0 3.5 10.8 1.1 0.0 18.5 3.7 4.6 0.0 29.5 3.9 3.2 5.1 3.5 3.8 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 3.0 1.4 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.1 64.2 0.0 0.0 0.1 17.2 30.6 0.0 0.0 0.0 0.0 0.1 0.0 30.2 114.9 0.5 0.0 52.3 58.0 70.1 1.2 0.0 0.0 113.6 0.8 11.4 0.0 0.0 21.3 4.8 2.5 0.5 0.4 0.3 50.1 17.9 0.4 0.0 0.4 0.3 0.0 0.4 0.5 37.9 0.0 19.8 0.0 1.0 2.5 2.7 0.0 2.8 0.0 3.1 0.0 0.0 6.6 1.7 0.0 0.0 3.4 0.0 4.8 10.6 0.0 1.8 3.6 4.7 35.8 8.4 5.7 0.0 0.6 0.9 1.7 0.0 0.0 0.8 24.8 0.0 1.1 0.3 26.2 2.5 6.2 1.9 0.6 10.8 1.1 0.9 3.3 1.5 2.4 0.0 0.0 0.1 25.7 0.8 0.0 0.3 0.0 0.6 0.6 9.1 3.6 21.0 5.9 2.9 0.2 2.7 2.0 0.5 6.3 0.1 2.2 10.8 3.0 0.0 2.1 19.2 0.0 5.0 23.3 0.3 2.1 9.8 0.0 9.4 14.8 0.2 0.0 2.0 0.6 0.9 0.5 0.7 14.4 2.9 1.7 0.6 0.5 1.4 19.7 10.8 15.6 0.2 4.8 1.7 2.3 0.3 1.3 3.3 1.0 3.8 CBFB PEBP2B ENSG00000067955 "Core-binding factor subunit beta" Q13951 16 67028984-67101058 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 243.7;U-698: 336.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038852 Uncertain Approved Nucleoplasm,Cytosol NA NA 18000 "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA038852: AB_10795358" "unprognostic (1.05e-1)" "unprognostic (1.18e-2)" "unprognostic (1.30e-1)" "unprognostic (3.22e-2)" "unprognostic (4.66e-2)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.83e-4)" "unprognostic (1.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-3)" "unprognostic (1.88e-2)" "prognostic unfavorable (2.89e-8)" "unprognostic (1.03e-1)" "unprognostic (4.31e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" 18.2 11.7 5.7 17.3 12.0 11.8 16.5 9.3 7.3 19.2 6.0 11.4 5.5 15.4 2.7 23.3 16.6 5.2 18.0 7.1 8.1 16.4 14.2 18.1 16.3 13.9 9.3 17.3 14.7 9.8 15.0 7.3 11.5 14.5 3.5 3.8 21.3 4.8 38.6 17.4 14.5 4.9 8.6 18.0 15.1 6.9 9.5 13.4 15.9 10.5 12.1 15.2 20.3 17.2 54.8 43.7 14.8 40.6 8.7 12.2 54.0 76.1 23.6 43.6 30.0 79.1 51.0 106.3 81.2 39.7 16.3 53.7 30.7 22.6 29.2 63.3 48.3 67.2 27.3 38.0 17.8 77.7 171.3 18.2 11.1 51.3 30.4 10.2 25.4 42.2 104.9 28.9 20.8 44.5 115.8 28.9 25.5 16.4 74.1 243.7 92.7 73.4 15.5 43.2 37.9 31.5 166.2 11.0 37.6 10.4 15.4 28.6 87.1 70.8 70.2 34.6 79.6 76.8 147.8 336.8 50.2 50.7 65.0 29.2 7.6 6.3 6.0 9.5 6.5 6.2 5.5 6.4 10.2 7.2 5.0 3.9 4.1 18.2 5.6 2.3 6.0 5.6 5.7 12.0 9.3 7.3 7.1 8.1 13.9 9.3 11.5 8.6 9.5 17.2 20.1 9.6 20.2 37.2 38.2 56.2 42.2 18.0 27.9 5.8 27.8 14.7 19.8 21.5 18.8 40.5 12.5 15.8 30.0 11.9 27.4 17.6 6.1 23.8 16.0 26.1 19.0 18.5 11.5 28.0 32.1 28.7 16.8 29.8 27.8 34.2 28.5 15.8 37.9 10.1 16.5 12.8 22.4 41.9 66.8 7.6 23.9 39.1 51.6 53.4 25.0 13.2 44.3 97.5 99.8 74.1 6.8 21.1 38.3 50.5 6.9 11.6 20.8 15.3 13.1 21.6 21.0 17.4 19.1 32.2 63.1 17.0 48.6 11.2 11.8 62.0 CBL "c-Cbl, CBL2, RNF55" ENSG00000110395 "Cbl proto-oncogene" P22681 11 119206298-119313926 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004350, HPA027956" Enhanced Approved Cytosol NA NA 67000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB004350: AB_2244054, HPA027956: AB_10601094" "unprognostic (2.52e-1)" "unprognostic (1.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-2)" "unprognostic (2.92e-1)" "unprognostic (4.10e-3)" "unprognostic (9.75e-2)" "unprognostic (1.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-2)" "unprognostic (5.23e-2)" "unprognostic (5.21e-2)" "unprognostic (5.27e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" 6.8 4.0 5.6 9.5 5.7 8.5 5.6 5.3 6.5 5.0 0.2 6.2 3.9 6.5 3.4 5.6 5.6 3.9 4.1 5.3 8.1 4.4 2.7 7.9 10.7 5.8 6.3 3.7 3.8 6.1 2.9 6.4 6.5 4.0 5.0 8.3 3.6 4.6 2.5 5.2 6.6 7.4 5.2 9.9 5.2 18.2 7.9 22.5 4.1 3.2 11.2 5.8 4.9 6.0 10.7 7.6 26.6 16.7 7.8 9.2 16.0 11.2 11.4 10.8 10.2 16.7 12.6 25.1 10.0 14.0 21.7 15.2 18.4 9.4 22.7 14.8 4.7 26.4 6.2 5.1 9.5 30.3 27.9 8.1 10.1 26.7 28.4 11.1 26.3 23.7 21.7 9.9 19.1 11.3 16.2 17.0 14.0 9.2 8.8 17.5 13.5 4.6 9.3 8.2 3.7 11.3 20.9 8.8 7.3 18.1 9.4 24.8 22.8 16.0 11.5 11.6 14.7 3.3 5.3 19.9 6.7 25.4 11.9 0.8 2.4 2.0 0.9 2.8 0.8 1.5 1.1 0.9 2.6 1.2 1.2 1.3 8.6 0.4 2.5 1.4 1.0 0.9 5.6 5.7 5.3 6.5 5.3 8.1 5.8 6.3 6.5 5.2 7.9 6.0 23.2 9.6 8.3 23.5 23.2 18.0 5.9 7.5 19.4 14.0 13.6 11.7 8.8 5.7 6.0 11.0 45.9 6.3 24.0 7.6 1.9 6.1 28.2 9.9 19.6 23.2 8.4 5.7 38.5 6.7 10.5 9.4 9.2 16.8 3.8 20.8 20.0 3.1 16.0 13.5 39.1 4.9 2.0 59.1 43.2 42.0 7.8 41.2 16.0 45.0 46.8 13.2 22.6 26.2 19.6 10.6 11.6 12.8 19.7 8.0 5.1 5.4 4.8 33.3 26.3 11.6 22.7 38.0 36.2 18.5 21.9 7.0 24.9 10.6 5.1 10.9 CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 113.7;Inhibitory neurons: 112.5;Oligodendrocyte precursor cells: 123.1;T-cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA018327: AB_1846097, HPA019880: AB_1846099" "unprognostic (2.65e-1)" "unprognostic (9.42e-2)" "unprognostic (1.72e-2)" "unprognostic (2.38e-1)" "unprognostic (5.89e-3)" "unprognostic (2.80e-2)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" "unprognostic (7.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.43e-2)" "unprognostic (8.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" 17.3 5.8 5.6 6.7 4.6 11.9 11.0 17.4 5.9 6.8 5.8 6.3 6.2 6.3 4.3 3.5 8.8 8.4 12.2 5.2 7.3 4.3 4.4 9.9 14.5 4.4 5.3 10.0 3.6 2.3 3.8 6.5 5.7 4.7 5.1 9.2 6.7 2.3 7.8 6.8 8.2 3.0 2.0 8.5 8.3 6.4 6.5 4.3 9.1 5.1 6.9 10.0 6.5 4.0 2.4 3.2 10.7 5.4 11.8 12.1 6.8 7.6 4.0 2.3 3.7 4.1 2.6 5.2 5.4 4.2 3.6 3.9 1.5 1.4 2.8 3.8 4.0 2.8 16.1 2.7 17.7 2.0 2.0 11.9 4.3 6.2 16.7 8.5 7.9 5.2 3.0 15.5 5.0 2.8 2.9 1.3 3.6 2.9 4.4 6.1 3.1 0.9 5.9 10.2 8.2 8.9 9.5 1.1 11.9 7.3 2.4 4.3 4.8 32.0 2.6 4.5 2.0 8.8 0.7 8.3 8.6 1.7 2.1 0.7 1.4 2.8 8.9 0.9 7.9 2.1 4.6 5.1 1.3 4.8 3.9 7.0 1.0 10.2 2.0 3.1 5.7 1.7 5.6 4.6 17.4 5.9 5.2 7.3 4.4 5.3 5.7 2.0 6.5 4.0 26.0 16.0 6.1 57.8 43.1 10.8 6.9 35.6 25.6 42.6 12.0 9.7 43.7 2.8 13.7 12.9 27.1 10.1 113.7 12.8 5.9 8.4 34.1 20.9 47.0 34.0 12.6 10.8 48.9 7.8 83.2 55.2 43.8 26.4 8.8 21.3 33.2 8.1 13.9 3.3 112.5 18.8 6.1 13.5 17.1 14.4 7.5 14.6 16.0 74.9 9.0 7.5 59.8 123.1 100.3 15.5 8.6 10.9 53.1 8.9 17.6 3.9 20.2 28.9 6.6 23.6 28.9 11.1 13.3 10.3 7.0 45.4 111.5 5.5 9.9 7.0 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.3;intestine: 50.9;skin 1: 42.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.6;Pancreatic endocrine cells: 95.0;Paneth cells: 108.1;Proximal enterocytes: 154.6;Undifferentiated cells: 67.1;Urothelial cells: 76.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 43.6;BEWO: 28.9;CACO-2: 28.3;CAPAN-2: 56.9;HaCaT: 41.0;HBEC3-KT: 34.8;hTCEpi: 26.0;OE19: 37.3;RT4: 34.7;SK-BR-3: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.1 0.0 3.1 0.0 0.0 5.1 0.0 0.1 8.0 0.0 25.0 50.9 0.9 0.1 39.3 2.5 4.4 0.0 0.0 0.0 7.4 21.1 1.3 0.0 0.0 0.0 0.1 20.6 1.6 0.5 0.4 0.0 11.8 11.7 0.1 13.3 2.4 0.1 42.4 38.6 0.6 0.0 0.0 17.7 0.7 0.0 0.3 1.7 0.0 4.0 8.3 18.4 0.0 43.6 0.0 0.0 0.1 0.0 0.0 28.9 0.0 0.0 0.0 0.0 28.3 56.9 0.0 0.0 0.0 0.0 41.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.3 0.0 0.0 0.0 0.0 0.0 34.7 0.4 0.1 0.0 31.1 0.0 0.2 22.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 15.0 44.0 30.8 16.5 0.0 9.3 7.4 0.2 4.3 27.7 7.3 0.0 5.8 0.2 108.6 1.9 53.8 0.1 7.0 1.3 0.9 17.4 0.0 0.4 48.9 2.3 0.5 59.7 15.5 0.0 0.0 0.0 11.1 0.3 0.0 0.9 40.0 18.3 0.0 1.4 0.3 0.0 0.4 0.0 0.0 0.6 0.0 0.0 1.0 0.3 95.0 108.1 0.0 0.1 34.4 154.6 17.2 9.8 0.0 0.0 0.0 1.3 0.0 2.6 29.9 25.7 2.5 0.7 0.0 67.1 76.9 CCAR1 "CARP-1, CARP1, FLJ10590" ENSG00000060339 "Cell division cycle and apoptosis regulator 1" Q8IX12 10 68721012-68792377 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007856, HPA048513" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Golgi apparatus" "HPA007856: AB_1078415, HPA048513: AB_2680424" "unprognostic (1.71e-1)" "unprognostic (1.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.86e-1)" "unprognostic (5.15e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "prognostic favorable (4.05e-5)" "unprognostic (2.89e-2)" "unprognostic (3.21e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.67e-1)" "unprognostic (2.36e-1)" "unprognostic (2.24e-1)" "unprognostic (1.41e-2)" 17.4 21.4 14.4 20.2 16.0 23.4 17.2 21.1 25.4 15.9 15.2 17.9 16.8 16.7 16.1 20.1 14.5 16.5 15.6 13.6 17.0 18.4 19.1 15.9 30.3 16.9 14.9 19.9 20.4 15.9 14.5 21.7 16.4 17.3 22.2 20.9 18.5 13.5 20.6 23.9 19.4 16.0 13.2 21.5 17.8 14.3 16.8 29.8 18.2 17.9 28.7 21.7 17.0 19.2 64.0 64.8 73.9 49.7 31.4 30.3 57.7 56.0 47.4 59.3 40.0 87.2 50.8 74.7 29.9 39.1 29.8 49.3 78.4 44.3 64.8 51.5 48.2 60.1 46.1 54.5 35.7 96.2 67.5 30.5 54.2 50.1 61.7 36.7 48.5 37.5 83.5 46.8 58.8 46.5 64.2 60.7 74.1 49.7 58.4 74.2 44.1 44.7 52.5 48.6 42.7 36.9 55.1 89.1 57.1 57.6 60.6 58.9 48.1 36.8 46.3 40.1 61.4 32.2 45.5 78.5 30.8 63.8 35.6 6.1 14.6 14.3 16.3 13.0 14.6 14.2 11.3 15.8 21.0 17.3 13.5 14.3 3.3 10.6 15.5 13.1 18.4 11.3 14.4 16.0 21.1 25.4 13.6 17.0 16.9 14.9 16.4 13.2 16.8 19.2 50.5 35.3 85.5 61.4 69.2 37.0 49.6 54.7 66.0 51.0 36.1 40.0 65.5 41.5 49.0 46.0 58.4 73.1 62.9 44.1 23.5 68.0 28.8 55.2 68.5 54.0 46.1 61.2 49.7 78.1 83.8 49.2 45.3 62.2 67.2 76.8 39.3 40.4 49.2 55.5 51.2 55.1 30.5 47.4 36.3 14.5 53.7 49.8 21.4 41.2 65.4 36.5 66.9 47.7 66.1 77.7 34.2 50.4 61.0 45.3 36.0 18.3 49.1 68.7 65.7 53.2 62.3 128.7 77.2 50.4 37.4 109.5 61.3 83.2 67.2 49.4 CCDC120 JM11 ENSG00000147144 "Coiled-coil domain containing 120" Q96HB5 X 49053572-49069857 "Cancer-related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;skin 1: 29.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 20.9;BEWO: 28.6;HaCaT: 19.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000561 Uncertain Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA000561: AB_2244190" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (7.59e-3)" "unprognostic (1.80e-3)" "unprognostic (1.08e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (4.85e-2)" "unprognostic (2.64e-2)" "unprognostic (3.82e-3)" "unprognostic (4.54e-3)" "unprognostic (2.34e-3)" 3.1 2.6 5.2 2.1 5.0 2.3 4.4 7.6 6.4 10.6 4.5 5.2 8.7 4.4 5.7 35.9 5.0 2.5 1.8 5.0 4.8 9.1 6.6 4.3 2.0 3.9 4.0 6.3 8.0 3.8 9.3 4.0 3.9 7.7 2.2 2.0 12.0 4.0 0.7 29.3 7.4 1.6 3.0 3.8 6.8 3.4 4.9 2.9 6.0 0.5 3.9 5.3 16.1 3.5 20.9 2.8 4.5 0.2 0.0 0.0 28.6 0.7 1.0 1.5 2.4 6.9 8.7 0.8 3.2 1.2 3.4 19.5 3.4 11.7 0.1 5.4 6.6 2.0 5.0 2.4 1.5 0.1 3.4 2.5 9.0 1.9 0.5 3.1 2.5 5.4 2.9 0.2 0.0 17.5 7.5 0.5 5.1 9.8 0.1 6.6 3.3 2.0 8.8 11.0 6.0 4.7 3.6 7.2 2.2 6.1 17.7 2.8 1.2 0.1 5.2 0.2 0.2 6.6 4.8 0.1 0.2 0.1 0.9 1.1 0.2 0.5 0.3 0.0 0.2 0.2 0.4 0.3 0.0 0.6 0.4 0.3 1.0 0.4 0.1 0.6 0.1 0.1 5.2 5.0 7.6 6.4 5.0 4.8 3.9 4.0 3.9 3.0 4.9 3.5 1.7 6.4 3.1 2.0 2.5 5.1 3.5 7.1 4.0 6.8 8.2 5.6 1.3 4.3 6.0 12.9 4.2 12.7 2.2 5.6 0.0 5.1 0.1 8.5 2.2 2.7 6.0 1.7 4.8 6.5 3.2 2.9 9.7 11.5 0.0 4.9 2.5 2.5 2.3 10.1 6.2 6.2 2.0 1.2 1.5 0.5 2.1 0.9 0.0 2.8 0.4 3.3 2.1 2.5 0.7 14.4 8.3 1.2 1.5 6.3 9.0 3.1 5.0 6.8 0.0 2.6 1.5 1.4 2.4 9.0 9.2 16.8 2.3 2.3 4.6 11.4 CCDC6 "D10S170, H4, PTC, TPC, TST1" ENSG00000108091 "Coiled-coil domain containing 6" Q16204 10 59788747-59906556 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019049, HPA019051" Enhanced Supported Cytosol No No 12000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "HPA019049: AB_1846163, HPA019051: AB_1846164" "unprognostic (1.88e-2)" "unprognostic (1.72e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-3)" "unprognostic (5.98e-3)" "prognostic favorable (5.48e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.39e-2)" "unprognostic (2.45e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.95e-4)" "unprognostic (4.08e-1)" "unprognostic (4.69e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-1)" "unprognostic (9.95e-2)" "unprognostic (4.19e-2)" 11.9 12.2 21.1 13.9 23.4 16.8 22.4 10.2 20.0 23.4 8.5 23.5 22.8 24.9 16.7 34.1 25.3 16.7 10.0 24.9 21.4 21.2 12.1 17.3 21.4 12.4 15.8 15.7 25.2 17.9 11.5 13.2 17.4 19.4 19.8 18.3 29.0 14.3 17.3 28.6 16.2 30.8 11.9 14.7 18.6 11.4 20.8 12.1 18.3 12.2 21.6 17.3 23.1 12.6 42.9 38.0 18.7 41.9 27.8 41.6 37.9 20.6 27.2 20.2 23.7 74.4 81.8 36.5 30.2 34.6 11.7 61.7 37.7 37.5 30.0 55.1 18.7 29.8 29.1 45.5 33.5 34.5 26.9 30.3 48.7 33.7 81.8 28.3 30.2 20.4 22.6 22.7 26.6 57.6 14.5 19.8 29.9 40.1 25.6 19.2 30.5 23.0 33.9 36.2 19.0 16.6 26.1 107.8 23.1 24.1 68.7 18.4 31.1 18.8 33.9 29.3 34.9 12.0 14.9 16.3 29.6 64.6 11.9 0.0 2.0 0.0 1.0 2.3 1.1 4.3 1.5 1.3 5.0 4.9 1.3 1.0 0.1 0.8 1.3 1.3 1.4 1.0 21.1 23.4 10.2 20.0 24.9 21.4 12.4 15.8 17.4 11.9 20.8 12.6 24.0 99.3 25.9 45.1 41.6 95.0 51.7 25.3 70.0 15.1 51.2 38.7 16.5 28.6 46.3 25.8 41.7 37.8 31.4 42.6 29.4 50.2 27.6 105.2 54.6 22.4 27.0 25.7 83.2 65.3 18.8 27.8 39.8 134.5 29.1 45.2 17.2 20.1 23.1 16.8 58.4 38.9 30.5 40.7 35.3 80.6 24.5 36.4 16.0 32.8 23.0 11.5 13.4 55.3 34.2 50.2 25.0 19.5 26.4 52.2 47.1 48.4 28.1 49.8 19.7 31.4 27.0 2.3 22.4 92.3 80.1 27.0 24.3 32.5 46.3 46.1 CCKBR ENSG00000110148 "Cholecystokinin B receptor" P32239 11 6259806-6272127 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "brain: 14.1;pancreas: 27.1;stomach 1: 42.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 14.6;Gastric mucus-secreting cells: 14.3;Granulosa cells: 23.3" "Cancer enriched" "Detected in some" 8 "testis cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "NTERA-2: 73.4" "Low region specificity" "Detected in many" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (2.82e-1)" "unprognostic (4.62e-2)" "unprognostic (1.79e-3)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (6.34e-4)" "unprognostic (8.01e-2)" "unprognostic (3.01e-2)" "unprognostic (9.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (1.30e-2)" 0.1 0.2 8.2 0.0 11.7 0.0 0.0 6.3 14.1 0.0 0.3 0.2 0.3 0.3 0.0 0.0 0.3 0.0 0.0 11.9 1.7 0.0 0.0 0.0 0.0 3.7 1.8 0.1 27.1 0.0 0.9 0.0 3.8 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.3 0.0 42.0 0.5 2.6 0.0 0.2 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 73.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.7 6.3 14.1 11.9 1.7 3.7 1.8 3.8 1.3 2.6 6.6 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 14.6 1.3 0.0 0.2 14.3 0.1 0.0 23.3 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.7 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CCL11 "eotaxin, MGC22554, SCYA11" ENSG00000172156 "C-C motif chemokine ligand 11" P51671 17 34285742-34288334 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.7;lymphoid tissue: 31.4;stomach 1: 35.1;urinary bladder: 41.0" "Cell type enriched" "Detected in some" 15 "Fibroblasts: 38.9" "Cancer enhanced" "Detected in many" "stomach cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "BJ hTERT+: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 88500 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.61e-2)" "unprognostic (1.45e-1)" "prognostic favorable (8.70e-4)" "unprognostic (8.18e-2)" "prognostic favorable (1.99e-4)" "unprognostic (9.91e-2)" "unprognostic (8.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (1.45e-1)" "unprognostic (9.64e-8)" "unprognostic (2.66e-2)" "unprognostic (1.05e-3)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" 3.8 0.8 0.0 31.4 0.0 0.0 0.2 0.0 0.0 3.6 0.0 41.7 33.2 1.7 0.0 12.4 0.7 4.8 16.7 0.0 0.0 5.8 0.6 9.1 0.0 0.0 0.0 0.3 2.8 1.7 1.0 0.0 0.0 2.6 14.7 0.0 0.1 0.9 0.0 0.0 35.8 20.5 0.0 2.8 35.1 0.0 0.0 0.3 0.0 0.0 0.7 41.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 9.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 1.9 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.1 CCL13 "CKb10, MCP-4, MGC17134, NCC-1, SCYA13, SCYL1" ENSG00000181374 "C-C motif chemokine ligand 13" Q99616 17 34356480-34358610 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.4;urinary bladder: 30.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 48.7;Langerhans cells: 81.2;Melanocytes: 17.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;BJ hTERT+: 1.7;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;HMC-1: 1.3;HSkMC: 1.7" "Secreted to blood" NA NA 336000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "unprognostic (2.22e-2)" "unprognostic (3.56e-2)" "unprognostic (8.41e-3)" "unprognostic (1.49e-3)" "unprognostic (4.43e-2)" "unprognostic (1.58e-1)" "unprognostic (7.58e-2)" "unprognostic (8.49e-2)" "unprognostic (1.18e-1)" "unprognostic (2.83e-2)" "unprognostic (1.35e-2)" "unprognostic (5.98e-2)" "unprognostic (8.63e-8)" "unprognostic (2.26e-1)" "unprognostic (2.57e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-2)" 24.0 4.5 0.0 7.0 0.0 0.3 18.4 0.0 0.5 3.2 0.0 30.4 21.3 0.6 0.3 11.9 4.4 2.7 11.8 0.0 0.0 1.7 0.2 22.5 3.2 0.0 0.0 0.3 0.7 1.6 0.1 9.7 0.0 1.6 25.1 0.0 2.6 0.8 0.6 4.5 27.0 9.0 0.0 0.1 2.9 2.4 0.0 8.7 1.8 5.8 1.8 30.4 3.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 1.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.0 0.0 0.0 8.8 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 81.2 0.3 0.0 6.6 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 0.0 0.1 4.7 0.3 1.0 0.0 0.0 0.1 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL16 "CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4" ENSG00000275152 "C-C motif chemokine ligand 16" O15467 17 35976493-35981497 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "liver: 120.3" "Cell type enriched" "Detected in some" 18 "Hepatocytes: 262.0" "Cancer enriched" "Detected in single" 154 "liver cancer: 49.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "Hep G2: 10.1" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 2780000 23000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (3.85e-1)" "unprognostic (4.71e-1)" "unprognostic (1.49e-1)" "unprognostic (3.75e-2)" "unprognostic (2.72e-1)" "unprognostic (4.58e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (1.91e-2)" "unprognostic (3.57e-1)" "unprognostic (1.40e-3)" "unprognostic (1.66e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (4.08e-2)" 0.7 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.2 0.1 0.5 0.0 0.2 0.5 0.2 0.2 0.0 0.0 0.3 120.3 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.0 2.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 262.0 0.0 0.0 0.0 0.2 0.0 4.1 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 CCL18 "AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18" ENSG00000275385 "C-C motif chemokine ligand 18" P55774 17 36064272-36072032 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lung: 48.7" "Group enriched" "Detected in some" 5 "Hofbauer cells: 189.1;Langerhans cells: 104.3;Macrophages: 153.1" "Cancer enhanced" "Detected in all" "lung cancer: 76.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 55500000 6400000 "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (8.91e-2)" "unprognostic (2.96e-2)" "unprognostic (5.71e-2)" "unprognostic (9.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" "unprognostic (2.50e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.68e-1)" "unprognostic (3.63e-1)" "unprognostic (4.87e-2)" 9.7 0.3 0.0 2.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 2.0 3.9 0.1 0.0 0.9 0.4 0.0 1.6 0.0 0.0 0.2 0.3 48.7 7.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 2.5 0.0 0.0 0.9 9.2 1.5 0.0 4.0 0.2 0.5 0.1 6.1 1.1 0.0 5.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 25.4 0.0 1.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 0.0 0.0 0.5 4.2 0.0 0.0 0.0 24.5 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.1 0.0 0.4 0.7 189.1 0.0 0.0 0.0 0.0 4.2 104.3 5.3 0.0 153.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.4 0.9 0.0 0.1 0.1 3.4 1.6 2.9 0.0 0.0 0.0 CCL19 "CKb11, ELC, exodus-3, MIP-3b, SCYA19" ENSG00000172724 "C-C motif chemokine ligand 19" Q99731 9 34689570-34691276 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 632.5" "Group enriched" "Detected in some" 12 "Basal keratinocytes: 74.7;Basal respiratory cells: 56.9;Fibroblasts: 59.6;Langerhans cells: 111.9;Melanocytes: 92.5;monocytes: 107.1;Smooth muscle cells: 150.9;Suprabasal keratinocytes: 54.0" "Cancer enhanced" "Detected in all" "testis cancer: 118.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HDLM-2: 3.2;TIME: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067758 Enhanced "Secreted to blood" NA NA 195000 63000 "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA067758: AB_2685897" "prognostic favorable (2.88e-5)" "prognostic favorable (9.91e-6)" "unprognostic (8.25e-3)" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (1.67e-2)" "unprognostic (1.30e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (8.36e-3)" "unprognostic (8.31e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (8.63e-7)" "unprognostic (7.98e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-1)" "unprognostic (1.87e-1)" 133.1 3.4 3.0 609.4 3.6 0.0 43.6 2.6 8.2 27.7 5.5 34.3 7.9 5.4 3.8 55.6 14.1 69.3 40.8 2.5 2.8 47.7 49.1 48.7 632.5 4.5 3.8 2.4 4.8 0.3 7.9 0.0 4.2 34.3 70.2 0.1 49.5 2.0 0.4 42.8 146.4 32.5 2.9 59.6 68.8 4.0 3.4 526.3 51.6 2.2 603.0 108.4 9.1 2.9 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.6 2.6 8.2 2.5 2.8 4.5 3.8 4.2 2.9 3.4 2.9 3.3 0.0 0.0 0.0 0.8 74.7 0.0 56.9 0.0 0.0 0.4 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 7.3 0.0 0.0 0.0 0.2 0.0 59.6 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 1.3 111.9 0.2 0.0 3.7 92.5 1.0 107.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 150.9 0.7 0.6 0.9 54.0 0.0 6.6 0.0 0.0 0.5 CCL2 "GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF" ENSG00000108691 "C-C motif chemokine ligand 2" P13500 17 34255218-34257203 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 756.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1152.5;Ductal cells: 3382.2;Exocrine glandular cells: 919.2;Prostatic glandular cells: 889.0;Skeletal myocytes: 994.7;Smooth muscle cells: 1507.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 7.5;eosinophil: 3.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.0;monocytes: 7.5" "Group enriched" "Detected in many" 4 "BJ hTERT+: 1902.2;HMC-1: 2427.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 9.9;spinal cord: 39.4" "CAB013676, HPA019163" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 323000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" Vesicles "CAB013676: , HPA019163: AB_1846179" "unprognostic (6.43e-2)" "unprognostic (4.14e-2)" "unprognostic (4.78e-2)" "unprognostic (5.57e-2)" "unprognostic (2.37e-3)" "unprognostic (8.64e-2)" "unprognostic (2.78e-2)" "unprognostic (7.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" "unprognostic (9.33e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (1.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.81e-1)" "unprognostic (4.92e-2)" 390.9 129.8 15.6 167.2 15.1 96.5 76.8 14.7 26.8 20.4 24.4 169.5 41.2 30.2 15.0 47.1 85.6 256.5 305.8 16.0 21.1 229.5 161.1 405.1 78.4 32.7 16.5 19.3 141.6 34.6 70.5 39.1 21.9 153.1 103.5 11.5 47.0 45.4 19.6 40.3 80.3 150.7 21.4 73.2 121.2 12.1 43.3 142.7 84.4 47.0 16.6 756.1 36.3 25.3 0.1 15.3 40.4 0.0 110.7 94.5 0.3 116.6 1902.2 243.3 516.8 7.1 0.2 0.3 90.4 27.6 3.8 64.0 4.3 0.1 122.9 0.6 0.9 0.2 13.5 0.0 3.5 0.4 2427.9 105.9 0.0 50.6 2.9 162.6 112.4 0.0 6.5 20.2 0.0 0.0 0.7 19.6 5.8 0.0 0.4 0.6 3.3 20.9 354.7 0.0 0.1 8.1 0.3 6.0 3.3 108.4 4.6 2.5 6.4 129.0 5.7 3.6 0.7 1.2 0.5 0.1 75.7 37.6 84.3 0.0 7.5 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.6 15.6 15.1 14.7 26.8 16.0 21.1 32.7 16.5 21.9 21.4 43.3 25.3 218.3 182.7 126.5 2.0 3.6 568.6 866.2 595.3 1152.5 0.1 23.5 50.9 29.5 92.9 120.7 138.0 0.0 2.7 2.2 0.0 0.0 3382.2 0.0 8.4 37.8 577.2 0.0 0.0 0.7 919.2 3.6 840.5 5.6 11.4 353.0 0.1 50.3 0.4 439.1 0.0 0.1 0.0 6.1 8.9 408.5 0.4 12.2 593.1 213.5 8.4 37.8 13.8 0.0 0.0 0.1 781.2 0.0 1.5 2.9 889.0 0.0 67.7 27.7 0.7 131.5 994.7 1507.0 0.4 0.3 13.0 222.8 4.5 44.3 1.7 0.1 40.6 CCL21 "6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4" ENSG00000137077 "C-C motif chemokine ligand 21" O00585 9 34709005-34710136 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 2726.3" "Cell type enriched" "Detected in many" 8 "Endothelial cells: 1213.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.1;K-562: 1.2" "Low region specificity" "Detected in some" HPA051210 Enhanced "Secreted to blood" NA NA 198000 920000 "Cluster 16: Immune cells - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051210: AB_2681390" "unprognostic (3.06e-3)" "unprognostic (7.19e-3)" "unprognostic (9.89e-2)" "unprognostic (5.50e-2)" "unprognostic (4.51e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" "unprognostic (8.07e-2)" "unprognostic (4.15e-2)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (8.99e-3)" "unprognostic (3.50e-3)" "unprognostic (1.58e-1)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 173.7 46.9 0.0 269.5 0.1 0.0 180.7 0.1 0.3 154.7 0.6 111.7 46.3 75.6 34.1 128.2 253.3 80.8 41.7 0.1 0.1 75.1 66.0 196.4 2726.3 0.4 0.0 33.9 15.3 0.8 2.5 1.7 0.2 38.2 135.7 0.0 21.5 19.0 6.8 46.4 498.8 69.0 0.0 336.8 60.9 10.3 0.1 28.8 519.4 30.6 998.8 74.1 50.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.7 0.2 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.0 0.1 0.2 58.4 22.4 53.3 0.0 1.9 145.3 2.4 3.8 1.8 0.0 13.5 4.3 10.1 0.0 13.0 1.8 0.0 0.2 1.4 0.2 0.0 10.0 5.7 0.1 0.3 1213.6 0.0 2.7 0.0 3.6 0.2 22.9 0.0 0.2 11.4 0.0 107.1 0.5 0.6 0.0 0.0 2.1 0.0 1.8 148.8 11.0 0.6 6.5 144.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.4 29.6 1.5 0.0 0.0 10.2 0.0 0.0 3.4 120.0 0.2 0.3 11.5 137.7 0.3 9.2 0.0 0.0 0.4 CCL23 "Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23" ENSG00000274736 "C-C motif chemokine ligand 23" P55773 17 36013056-36017972 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Hepatic stellate cells: 243.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 163 "eosinophil: 183.7" "Lineage enriched" "Detected in many" 163 "granulocytes: 183.7" "Group enriched" "Detected in some" 4 "HEL: 17.6;THP-1: 37.4" HPA042015 Uncertain "Secreted to blood" NA NA 937000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042015: AB_10794039" "unprognostic (1.65e-3)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (9.50e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (1.20e-4)" "unprognostic (2.17e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-2)" "unprognostic (7.05e-2)" "unprognostic (6.93e-2)" "unprognostic (1.35e-3)" "unprognostic (2.18e-1)" "unprognostic (2.76e-1)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" 7.9 6.7 0.0 7.0 0.0 3.7 7.3 0.0 0.2 18.5 0.1 4.3 0.2 14.8 1.6 4.7 11.9 3.3 0.7 0.0 0.0 12.0 7.5 21.4 1.6 0.0 0.0 2.9 1.0 0.0 0.3 0.3 0.0 8.6 8.7 0.0 3.5 0.3 0.5 3.6 9.3 10.8 0.0 14.1 3.3 0.6 0.1 0.8 3.1 0.1 1.3 5.5 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 2.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 1.0 0.7 183.7 0.1 0.7 0.0 1.0 0.0 0.4 0.7 0.0 0.0 0.4 0.7 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.5 3.2 2.3 0.0 0.9 1.7 0.4 0.0 0.0 0.0 0.1 0.3 0.2 1.5 0.6 0.0 0.0 0.0 0.7 1.6 0.0 0.0 1.6 0.0 0.2 44.6 0.0 5.7 0.0 0.0 0.0 0.7 0.0 0.0 10.1 0.0 243.8 2.6 7.0 0.0 0.0 0.5 0.0 14.7 2.7 0.1 0.0 3.7 1.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21.4 0.0 0.1 0.1 0.5 0.1 1.5 0.0 0.0 0.0 0.5 0.0 0.1 0.1 2.7 0.3 0.6 0.0 4.2 0.2 CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.7;lung: 35.8;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in many" "dendritic cells: 441.4;Hofbauer cells: 2084.4;Kupffer cells: 723.2;Langerhans cells: 710.0;Macrophages: 1534.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.6" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.6" "Cell line enhanced" "Detected in some" "Karpas-707: 443.8;U-266/70: 602.5;U-266/84: 2043.3" "Secreted to blood" NA NA 138000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (7.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-1)" "unprognostic (8.90e-2)" "unprognostic (7.92e-3)" "unprognostic (2.00e-1)" "unprognostic (7.20e-2)" "unprognostic (2.05e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-2)" 17.6 16.0 0.0 8.1 0.7 76.7 5.6 0.0 1.4 1.5 0.0 2.5 0.0 1.1 0.0 0.5 2.9 10.3 3.7 0.0 0.0 4.6 12.9 35.8 1.8 0.7 0.0 1.2 1.3 0.0 1.7 2.4 0.0 2.2 0.0 0.0 5.6 0.0 0.8 0.8 3.1 0.0 0.0 49.4 3.0 0.7 0.5 0.0 2.0 0.0 0.0 3.0 1.4 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.8 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 55.6 0.0 0.0 1.3 602.5 2043.3 0.0 0.0 0.0 0.0 0.0 2.1 10.8 23.6 1.3 0.0 5.1 0.0 6.1 0.4 10.4 0.1 6.8 10.5 3.5 1.3 0.0 0.0 11.6 0.0 0.7 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.5 1.4 33.0 0.0 28.6 0.0 45.3 27.9 2.0 0.2 1.2 1.8 23.1 50.0 2.2 4.3 4.4 0.0 0.0 19.0 441.4 0.7 0.0 0.6 1.5 1.6 2.5 115.9 0.0 61.9 0.0 0.2 22.6 14.5 2.0 2.8 23.5 0.1 27.1 9.1 2084.4 0.0 0.0 0.5 0.0 723.2 710.0 1.9 1.8 1534.2 94.3 2.8 23.5 2.1 106.1 0.0 0.0 0.4 0.0 0.0 344.8 1.2 0.0 0.9 2.2 3.7 6.6 2.3 9.2 0.5 0.6 0.6 28.8 54.3 248.0 0.1 0.2 1.3 CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "dendritic cells: 3753.7;Hofbauer cells: 849.7;Macrophages: 1168.2;NK-cells: 1232.8;Plasma cells: 974.5;T-cells: 1948.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Group enriched" "Detected in some" 6 "U-266/70: 51.6;U-266/84: 13.3" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" 38.9 28.0 2.0 32.0 2.0 192.9 10.5 3.4 5.5 16.0 4.1 9.9 7.6 10.3 6.4 15.0 8.2 45.1 4.4 2.0 1.9 6.8 84.2 33.9 34.3 3.2 2.9 5.0 15.6 12.0 2.5 17.8 2.8 7.6 11.1 0.1 5.1 3.4 1.0 0.9 11.4 18.0 2.5 65.3 10.3 2.7 2.1 24.1 5.9 4.5 15.4 56.4 4.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 51.6 13.3 0.2 0.2 0.1 0.0 14.4 3.4 135.0 414.7 4.8 101.6 8.4 46.0 240.6 2.3 17.7 13.8 181.7 55.8 42.8 11.1 2.6 0.5 138.9 2.0 2.0 3.4 5.5 2.0 1.9 3.2 2.9 2.8 2.5 2.1 3.3 52.3 0.0 54.5 0.0 135.9 15.6 1.9 0.3 24.5 1.5 26.3 49.3 11.2 14.3 7.2 0.0 0.0 9.7 3753.7 1.2 0.0 0.4 20.8 3.7 4.7 77.6 1.2 60.9 0.0 0.4 11.3 18.9 118.3 5.5 60.8 0.2 21.4 10.5 849.7 1.7 0.0 1.5 0.0 429.4 428.0 32.6 0.9 1168.2 51.6 3.7 10.5 1.1 1232.8 0.0 0.0 0.2 0.1 0.4 974.5 0.8 0.4 2.8 5.8 5.2 0.0 3.9 20.9 0.4 0.4 11.0 14.5 25.9 1948.3 0.0 0.9 1.6 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCL7 "FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7" ENSG00000108688 "C-C motif chemokine ligand 7" P80098 17 34270221-34272242 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 25.9" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 56.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.5;BJ hTERT+ SV40 Large T+: 2.3;BJ hTERT+ SV40 Large T+ RasG12V: 2.8;HSkMC: 3.3" "Not detected" "Not detected" "Secreted to blood" NA NA 29700 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (7.66e-2)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (4.65e-2)" "unprognostic (2.54e-2)" "unprognostic (9.54e-2)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (2.63e-2)" "unprognostic (2.27e-3)" "unprognostic (7.04e-2)" "unprognostic (1.99e-8)" "unprognostic (2.83e-1)" "unprognostic (8.74e-2)" "unprognostic (3.74e-1)" "unprognostic (1.79e-2)" 0.8 0.2 0.0 2.5 0.0 25.9 0.1 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.7 0.3 0.0 0.0 0.5 0.2 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 2.3 0.3 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 11.5 2.3 2.8 0.0 0.0 0.0 0.4 0.8 0.0 1.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 3.3 0.0 0.9 0.0 0.0 1.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 CCL8 "HC14, MCP-2, SCYA8" ENSG00000108700 "C-C motif chemokine ligand 8" P80075 17 34319435-34321402 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Smooth muscle cells: 104.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 6 "monocytes: 3.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.0;EFO-21: 2.1;HSkMC: 3.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 32000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (7.51e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-2)" "unprognostic (8.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (9.97e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.05e-7)" "unprognostic (1.39e-1)" "unprognostic (1.88e-2)" "unprognostic (5.65e-2)" "unprognostic (3.41e-2)" 17.5 4.7 0.4 5.1 0.4 1.8 6.2 0.4 0.9 1.5 0.5 18.1 14.1 7.3 1.9 3.5 1.3 8.8 2.7 0.4 0.4 7.7 3.2 7.1 3.9 0.6 0.4 1.4 1.1 4.8 0.5 7.1 0.6 2.2 16.4 0.0 1.9 1.3 0.4 0.5 17.0 9.3 1.8 2.9 2.9 3.1 1.1 12.5 2.3 7.0 0.5 13.7 0.3 0.6 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.4 0.9 0.4 0.4 0.6 0.4 0.6 1.8 1.1 0.6 21.5 0.0 0.0 0.0 0.1 4.2 0.3 0.5 0.0 0.0 0.9 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 10.5 0.9 7.5 9.6 0.0 0.0 0.0 2.0 0.0 16.4 0.0 1.6 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 3.5 18.6 2.2 0.0 12.7 5.4 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.3 104.3 0.0 0.0 0.0 5.4 0.1 0.8 0.7 0.0 0.1 CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 101.2;Cardiomyocytes: 38.7;Extravillous trophoblasts: 47.1;Fibroblasts: 261.8;Smooth muscle cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Cell line enhanced" "Detected in many" "EFO-21: 1605.0;HUVEC TERT2: 1377.0;TIME: 2874.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" No No 1010000 5900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 265.9 107.5 18.9 168.0 18.8 2.0 206.4 16.3 34.0 531.0 31.5 148.8 43.7 418.5 34.4 271.9 243.8 441.4 371.8 25.8 14.2 235.7 82.9 226.3 73.6 18.8 32.1 77.0 194.0 43.0 44.8 198.2 20.2 364.6 136.1 2.4 138.2 154.3 51.8 155.1 151.2 576.3 14.2 569.1 182.6 24.7 20.8 49.5 464.7 61.9 14.9 324.0 102.5 18.2 4.6 7.5 126.8 3.7 279.9 158.5 1.8 373.1 178.2 226.8 119.4 0.2 12.2 0.6 1605.0 482.7 185.0 6.2 4.2 26.4 211.3 2.5 3.5 0.2 55.7 137.3 109.6 0.3 0.5 232.2 5.9 163.9 40.2 340.7 1377.0 0.0 0.4 0.3 650.8 2.5 0.5 1.2 61.8 41.3 21.7 32.6 6.0 0.7 81.9 0.4 0.5 0.8 38.3 62.2 18.3 308.5 6.1 3.1 2874.4 311.6 242.4 397.8 694.0 11.5 1.7 4.1 42.5 0.7 399.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.9 18.8 16.3 34.0 25.8 14.2 18.8 32.1 20.2 14.2 20.8 18.2 101.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 0.0 17.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 47.1 261.8 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 CCN4 "WISP-1, WISP1, WISP1-OT1, WISP1-UT1" ENSG00000104415 "Cellular communication network factor 4" O95388 8 133191039-133231690 "Cancer-related genes, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 110.5;hTEC/SVTERT24-B: 64.5;U-2197: 61.9" "Region enriched" "Detected in some" 6 "olfactory bulb: 9.8" "Low region specificity" "Detected in many" "HPA007121, CAB012205" Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB012205: , HPA007121: AB_1858844" "unprognostic (7.77e-2)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (3.20e-1)" "unprognostic (7.72e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.26e-2)" "unprognostic (2.07e-3)" "unprognostic (1.41e-3)" "unprognostic (3.01e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (7.52e-3)" "unprognostic (2.55e-3)" "unprognostic (6.03e-2)" "unprognostic (5.67e-3)" 4.4 10.3 1.3 7.6 2.6 0.0 0.9 0.5 1.4 10.9 0.9 3.9 1.2 14.0 0.9 0.9 5.9 7.8 3.7 1.3 0.4 15.8 2.0 8.3 3.0 0.7 0.6 6.0 0.8 9.2 2.3 2.8 0.7 3.3 0.8 0.0 1.1 1.4 0.4 1.4 2.3 13.6 0.6 2.2 2.8 1.2 0.9 0.2 1.1 0.2 3.9 6.0 3.6 0.8 0.0 0.5 0.0 0.0 7.6 4.2 0.1 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 110.5 0.0 64.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.0 0.0 0.0 14.8 0.8 61.9 0.0 0.0 0.0 0.0 12.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.6 0.5 1.4 1.3 0.4 0.7 0.6 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCNA1 CT146 ENSG00000133101 "Cyclin A1" P78396 13 36431520-36442870 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.2;testis: 81.3" "Group enriched" "Detected in some" 5 "Early spermatids: 162.4;Endometrial ciliated cells: 119.1;Late spermatids: 91.1;Spermatocytes: 285.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 20.7;head and neck cancer: 6.2;ovarian cancer: 18.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 103 "basophil: 49.2" "Lineage enriched" "Detected in single" 301 "granulocytes: 49.2" "Cell line enhanced" "Detected in many" "HMC-1: 350.9;NB-4: 71.4;THP-1: 71.5;U-937: 90.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA060646, HPA077614" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA060646: AB_2684336, HPA077614: " "unprognostic (1.92e-3)" "unprognostic (1.21e-1)" "unprognostic (4.69e-3)" "unprognostic (1.89e-3)" "unprognostic (5.46e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (1.24e-1)" "unprognostic (4.01e-3)" "unprognostic (1.64e-1)" "unprognostic (4.04e-6)" "unprognostic (7.04e-3)" "unprognostic (2.45e-1)" "unprognostic (1.42e-1)" "unprognostic (2.63e-2)" 0.4 0.9 5.9 0.4 5.9 2.1 0.7 2.3 7.8 5.8 4.1 0.6 0.4 3.7 7.0 0.4 18.0 0.7 0.3 5.5 7.3 0.5 0.1 1.4 0.3 5.3 5.4 0.5 0.1 22.2 8.2 0.0 10.7 0.5 0.1 1.0 0.6 0.1 1.2 0.3 0.3 8.2 4.9 0.6 0.4 81.3 6.1 0.4 0.6 0.4 0.6 0.6 1.1 4.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 15.2 0.1 15.5 1.2 12.9 1.4 0.1 0.0 0.7 0.0 0.4 0.0 0.6 8.0 350.9 0.3 34.1 0.7 2.8 5.5 0.9 1.7 0.0 0.5 0.2 4.4 0.4 71.4 2.5 0.0 8.8 0.0 8.3 0.0 2.3 0.0 2.5 5.8 0.0 8.4 0.2 1.8 0.0 71.5 4.5 0.0 0.0 0.1 2.9 0.8 0.0 0.0 0.3 90.3 0.6 49.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.9 5.9 2.3 7.8 5.5 7.3 5.3 5.4 10.7 4.9 6.1 4.0 0.1 0.0 0.6 0.3 0.3 0.6 0.6 19.1 0.0 0.4 0.5 1.4 0.4 0.0 10.3 0.0 0.0 0.1 0.0 0.1 0.0 0.2 162.4 119.1 1.8 0.4 0.0 0.0 3.5 0.0 0.8 1.1 0.0 31.9 5.1 2.2 0.0 0.0 0.2 0.0 3.0 0.0 6.1 0.0 1.8 91.1 3.1 1.1 0.0 0.0 0.0 1.4 0.0 0.5 0.4 0.0 0.0 2.6 0.0 0.7 0.0 0.1 29.3 0.8 6.6 0.5 1.5 285.7 2.4 0.0 0.4 0.3 0.9 0.0 0.1 1.1 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 723.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 4.0 5.1 4.0 26.0 3.9 52.9 10.0 6.0 4.9 6.3 2.8 22.2 20.9 7.7 5.4 36.0 8.2 4.0 3.0 3.8 4.0 4.8 4.3 3.9 54.5 6.2 4.4 5.0 4.2 5.8 2.6 20.8 6.5 3.8 29.5 5.7 6.5 3.9 3.4 14.5 19.5 14.4 3.5 11.1 10.8 32.9 5.2 76.2 9.3 2.0 67.0 8.4 10.4 4.0 466.0 317.1 423.5 377.1 22.2 37.1 980.2 201.3 150.8 521.3 437.0 471.2 423.9 285.2 239.1 187.6 594.2 284.2 432.4 442.8 577.2 281.4 217.2 181.6 243.2 323.2 6.8 160.5 197.7 16.6 27.7 300.5 207.2 47.7 282.8 274.2 223.5 217.9 430.2 441.4 220.5 184.7 236.7 153.3 199.3 228.4 305.2 288.2 192.6 168.2 212.7 133.5 347.7 160.3 141.9 236.4 306.4 162.5 119.8 114.4 368.5 207.6 510.2 109.2 216.6 399.8 158.8 271.9 358.6 3.1 2.0 1.5 3.2 5.1 4.5 15.4 8.3 7.4 6.0 11.1 2.7 2.6 1.3 8.2 2.4 5.0 17.6 6.2 4.0 3.9 6.0 4.9 3.8 4.0 6.2 4.4 6.5 3.5 5.2 4.0 4.0 0.0 0.5 2.0 11.8 11.5 7.2 32.1 4.6 4.8 9.8 12.3 1.9 1.5 8.8 5.5 2.1 108.2 8.3 9.5 1.9 6.5 110.2 15.2 7.4 6.6 1.2 76.2 2.7 1.4 723.1 18.3 21.4 13.0 2.5 63.0 8.9 3.2 60.2 0.0 2.1 13.8 73.2 12.0 7.2 17.8 3.1 9.7 3.6 1.0 2.7 3.9 2.1 0.5 1.0 2.4 1.5 2.6 24.1 4.5 2.5 5.6 13.1 4.1 6.6 4.9 18.5 74.3 62.2 37.4 7.2 41.5 8.0 11.8 33.4 7.8 CCNB1IP1 "C14orf18, HEI10" ENSG00000100814 "Cyclin B1 interacting protein 1" Q9NPC3 14 20311368-20333312 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 381.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.37e-2)" "unprognostic (5.46e-3)" "unprognostic (2.79e-2)" "unprognostic (8.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.88e-2)" "unprognostic (4.87e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.18e-6)" "unprognostic (2.12e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-1)" "unprognostic (1.52e-1)" 31.3 20.0 31.7 10.6 32.8 35.5 58.1 31.8 44.3 52.6 38.4 35.3 21.3 43.0 48.4 27.3 53.2 20.8 74.7 31.1 35.3 66.4 74.9 36.9 25.3 34.7 32.7 99.4 45.3 51.3 22.2 31.3 34.9 38.1 30.1 21.2 29.6 24.4 52.2 35.5 24.7 29.9 32.7 20.4 31.0 23.3 31.8 32.0 57.4 63.4 30.7 40.0 41.7 34.4 30.8 24.7 137.5 133.3 68.9 94.1 110.3 37.0 73.6 55.5 72.8 83.2 33.4 106.2 23.9 27.1 55.6 53.8 96.6 69.9 74.3 30.9 82.0 63.1 22.6 79.7 201.7 117.5 56.6 128.8 114.6 39.6 381.3 67.3 42.6 125.7 77.7 82.1 37.0 48.9 68.5 79.3 83.2 66.5 46.6 82.9 67.9 45.5 58.7 44.6 109.0 113.6 25.5 58.5 170.7 75.8 18.7 84.5 18.4 31.6 40.1 38.4 48.8 38.3 51.0 72.6 10.6 97.3 37.1 6.3 4.2 0.1 8.2 1.4 10.9 11.6 9.0 10.3 17.7 9.8 9.2 13.0 0.6 6.0 1.6 18.2 13.3 3.8 31.7 32.8 31.8 44.3 31.1 35.3 34.7 32.7 34.9 32.7 31.8 34.4 22.2 28.9 27.2 16.3 35.5 58.1 74.0 45.5 113.3 4.2 57.0 71.9 30.9 58.6 21.0 23.9 20.9 41.2 27.7 15.1 103.7 31.8 64.2 13.0 37.6 24.9 41.3 34.7 22.2 38.2 70.6 34.5 23.0 20.2 34.9 76.7 20.0 35.3 17.8 1.7 28.5 40.1 28.5 23.3 26.5 92.8 51.6 22.4 51.6 7.5 17.8 46.9 30.9 15.1 19.7 29.3 18.8 44.0 17.4 63.5 21.0 86.5 5.2 17.6 46.0 36.6 31.6 101.0 77.5 67.0 40.1 34.1 28.7 61.1 44.3 51.3 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 499.7;Ductal cells: 504.0;Pancreatic endocrine cells: 622.1;Urothelial cells: 412.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 874.2;WM-115: 1239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" 55.6 29.2 12.1 10.0 14.6 1.5 40.2 15.0 11.9 17.0 33.4 19.8 22.7 14.8 27.6 72.9 30.8 19.5 64.9 10.8 14.6 32.2 107.3 61.1 10.5 17.5 15.5 4.6 86.3 82.7 25.7 63.7 18.3 53.3 17.2 3.2 30.4 50.4 3.6 120.3 16.0 23.3 15.9 37.2 52.7 3.2 21.7 9.9 45.5 5.2 19.0 29.5 43.9 24.0 467.3 183.0 59.5 1.8 178.3 186.7 127.4 717.5 264.9 82.1 47.6 206.9 349.9 0.1 317.6 375.5 137.2 332.1 6.5 195.2 146.0 1.2 36.5 0.3 46.7 211.7 43.3 3.3 6.7 106.5 37.9 116.0 44.0 192.5 142.1 0.2 0.6 1.3 654.2 197.1 0.4 26.6 109.0 190.7 198.3 1.2 187.9 11.3 379.4 282.8 10.0 231.4 9.2 167.7 458.4 143.5 102.6 9.5 600.4 399.5 111.0 176.1 496.2 874.2 559.4 1.5 341.6 5.9 1239.0 0.2 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 1.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.1 14.6 15.0 11.9 10.8 14.6 17.5 15.5 18.3 15.9 21.7 24.0 84.6 182.7 115.6 0.3 8.3 202.5 234.7 499.7 133.1 2.3 163.4 140.0 80.0 92.9 271.6 125.0 2.1 10.9 2.4 44.8 31.3 504.0 0.4 104.2 23.5 141.0 56.5 2.5 0.5 142.6 1.2 67.6 127.4 199.5 29.1 0.0 98.2 165.2 75.0 0.0 2.2 42.6 75.3 18.8 61.9 2.0 4.1 23.6 51.6 17.8 2.4 79.1 0.0 49.8 0.3 622.1 118.0 57.6 0.5 262.0 19.4 57.1 85.9 3.1 131.5 13.0 184.8 0.5 23.4 292.3 351.1 2.5 8.8 3.4 82.2 412.6 CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 354.3;Granulosa cells: 438.5;Langerhans cells: 255.3;Plasma cells: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 152.4;HBEC3-KT: 136.6;HDLM-2: 238.8;Karpas-707: 287.9;RH-30: 202.7;RPMI-8226: 114.2" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA049138: AB_2680650, HPA054196: AB_2682412" "unprognostic (2.98e-3)" "unprognostic (1.15e-1)" "unprognostic (7.21e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (4.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.01e-3)" "unprognostic (3.16e-2)" "unprognostic (1.66e-2)" "prognostic favorable (2.52e-4)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (8.23e-2)" "unprognostic (4.52e-1)" "prognostic favorable (9.76e-5)" "unprognostic (7.06e-2)" 20.0 52.6 5.4 8.7 12.9 20.3 13.0 0.0 13.5 26.9 0.0 40.8 17.4 26.1 7.5 12.2 22.1 2.7 51.9 14.4 1.1 9.7 1.9 17.2 5.3 9.6 0.2 14.2 24.5 9.9 23.5 12.9 2.7 20.7 10.4 0.7 10.8 9.1 1.8 12.6 25.9 9.8 7.8 19.7 12.7 4.0 0.0 3.2 20.3 0.0 5.1 26.5 19.9 4.5 0.0 0.0 152.4 0.0 10.1 0.4 0.0 0.0 0.0 0.0 0.0 62.8 0.0 0.0 0.4 0.0 0.0 16.2 0.1 136.6 0.0 238.8 2.5 0.7 0.0 0.0 0.0 57.0 12.6 23.8 2.4 0.0 97.0 0.0 0.0 0.8 17.0 287.9 6.8 0.0 0.0 52.8 50.8 0.0 0.0 0.0 202.7 114.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 89.6 0.0 0.0 4.2 0.0 39.3 0.0 0.0 1.4 60.7 0.0 0.0 32.3 0.0 6.6 0.4 4.7 11.1 0.0 17.1 3.1 16.3 13.8 0.4 1.7 10.4 12.1 1.1 9.4 0.0 1.1 13.6 6.8 5.4 12.9 0.0 13.5 14.4 1.1 9.6 0.2 2.7 7.8 0.0 4.5 23.9 60.9 46.6 10.1 82.9 106.8 23.9 73.4 174.2 7.6 3.4 41.8 354.3 2.8 37.4 12.9 0.0 4.0 128.7 37.5 0.0 3.1 0.8 3.3 110.8 35.7 64.8 37.2 54.1 68.3 2.7 123.6 4.6 3.6 55.8 438.5 19.6 2.2 13.0 3.3 55.2 147.7 12.2 11.9 255.3 3.3 52.5 39.3 39.2 19.7 9.8 170.0 89.6 55.3 4.0 20.7 49.4 124.1 371.2 35.8 34.4 1.4 10.3 6.5 26.3 21.4 112.6 0.8 5.1 50.9 39.6 6.3 122.6 41.5 159.7 8.4 CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934934-42050357 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 256.6" "Cell type enhanced" "Detected in all" "NK-cells: 555.1;Syncytiotrophoblasts: 236.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 696.3;REH: 651.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA042871" Approved Supported Nucleoplasm NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "CAB000116: , HPA042871: " "unprognostic (4.53e-2)" "unprognostic (4.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (9.80e-2)" "unprognostic (3.40e-2)" "unprognostic (5.25e-2)" "unprognostic (7.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.17e-2)" "unprognostic (6.39e-2)" "unprognostic (2.45e-3)" "unprognostic (9.12e-2)" "unprognostic (1.71e-1)" "prognostic favorable (8.08e-6)" "unprognostic (2.11e-1)" 74.3 137.6 84.8 63.1 84.6 220.2 64.8 80.0 94.5 36.9 78.4 45.6 40.6 35.4 15.3 39.6 43.2 34.4 68.1 86.2 88.6 42.4 22.1 102.5 143.3 87.4 82.5 36.0 31.6 23.7 33.3 55.4 84.0 50.4 27.0 10.3 50.4 25.6 18.2 52.3 78.5 28.6 79.7 170.4 66.1 11.1 86.4 256.6 58.7 32.5 83.6 45.4 44.3 80.8 67.7 242.2 24.6 54.8 43.7 88.6 286.1 77.1 43.7 77.7 57.1 45.9 29.7 288.9 127.8 51.9 68.9 40.5 65.8 93.4 39.2 49.2 43.4 458.8 106.6 37.3 94.9 75.9 385.2 84.7 59.8 76.0 27.9 23.5 96.6 188.3 236.7 27.2 111.6 92.0 696.3 354.6 10.9 202.8 51.5 651.8 96.3 32.2 179.1 44.9 83.8 21.8 65.8 83.3 38.6 30.6 51.5 288.4 162.9 86.2 47.9 74.7 88.1 17.9 15.2 458.5 50.4 157.6 53.3 1281.3 246.3 725.1 390.4 294.4 276.5 127.1 266.4 318.1 343.3 180.8 306.4 328.3 339.3 333.2 405.6 221.4 193.0 635.4 84.8 84.6 80.0 94.5 86.2 88.6 87.4 82.5 84.0 79.7 86.4 80.8 102.2 60.9 67.9 31.0 102.9 27.0 95.8 52.3 48.9 19.6 49.9 45.1 26.2 64.3 27.8 20.2 6.2 201.0 227.3 66.4 29.4 20.3 12.8 12.1 10.8 68.3 9.6 133.6 37.1 24.3 82.4 32.3 19.9 11.2 26.6 7.7 70.6 7.2 45.3 11.8 23.7 19.5 50.8 115.7 51.7 9.4 41.3 152.2 37.4 47.8 79.0 40.8 555.1 18.1 9.3 29.9 30.5 51.9 48.7 40.3 18.6 19.8 22.5 16.2 46.0 19.2 31.9 4.3 6.3 21.7 22.6 236.6 195.0 141.6 32.7 52.8 CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;placenta: 30.8" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 1756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "BEWO: 293.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" 1.2 5.7 1.9 4.3 2.1 35.8 0.8 2.8 2.7 1.0 0.9 3.9 3.0 1.4 0.6 4.4 0.9 1.0 2.3 2.0 2.5 1.0 0.7 1.1 6.1 2.0 2.1 0.8 1.8 2.8 0.9 30.8 2.0 1.0 4.7 2.0 1.5 1.4 2.1 4.1 2.5 2.2 1.7 4.2 2.1 12.1 2.5 4.5 1.6 1.8 7.8 3.0 1.8 2.3 15.6 31.8 24.3 34.0 5.2 6.0 293.1 24.7 5.3 10.8 13.2 33.0 31.2 13.3 55.9 11.1 14.0 4.9 28.8 12.8 15.2 41.9 17.7 11.2 30.0 34.5 4.1 44.0 28.7 6.2 7.1 14.8 1.9 3.4 13.3 13.2 45.6 5.8 16.8 24.4 24.5 13.0 40.1 36.2 7.2 36.2 28.6 10.1 8.4 24.6 20.5 17.4 35.4 42.7 3.9 35.4 9.5 32.7 8.0 25.0 92.8 14.9 16.9 24.1 18.2 91.6 13.8 5.6 13.7 0.0 0.0 0.0 0.1 0.5 0.3 0.6 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.3 0.1 1.9 2.1 2.8 2.7 2.0 2.5 2.0 2.1 2.0 1.7 2.5 2.3 3.1 0.0 0.6 0.7 4.8 4.8 1.5 0.3 2.2 2.9 8.2 11.3 3.1 0.0 1.4 0.0 0.0 122.4 3.7 3.5 0.0 0.4 14.6 7.5 4.1 1.9 3.0 30.7 2.9 0.7 1756.5 6.0 5.6 20.1 0.0 4.6 1.4 0.2 43.4 3.3 5.1 3.3 0.0 1.0 2.5 3.6 1.2 4.2 1.8 0.0 0.2 1.7 0.0 2.5 1.3 1.4 2.2 2.2 18.4 2.2 1.0 0.4 0.1 1.1 6.6 4.1 3.4 25.0 17.6 8.5 6.0 115.7 4.5 6.9 4.9 3.5 CCNE2 CYCE2 ENSG00000175305 "Cyclin E2" O96020 8 94879770-94896678 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.6;Oligodendrocytes: 34.5;Spermatocytes: 77.7;Spermatogonia: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 101.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007825, CAB019374" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB007825: AB_598148, CAB019374: " "unprognostic (1.80e-2)" "unprognostic (4.81e-2)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (2.36e-1)" "prognostic favorable (5.87e-4)" "unprognostic (8.37e-4)" "prognostic unfavorable (8.77e-4)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.64e-2)" "unprognostic (1.04e-2)" "unprognostic (7.01e-12)" "unprognostic (1.81e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.03e-1)" 2.0 0.6 3.7 6.9 8.3 37.0 2.2 9.0 7.7 1.7 0.3 5.4 3.6 1.8 0.1 4.7 0.6 2.4 1.4 3.2 5.4 0.5 2.3 1.8 10.9 9.9 8.1 1.5 1.8 0.5 0.6 4.3 8.8 1.2 5.7 5.2 1.8 0.2 0.7 5.9 4.3 2.2 7.4 2.3 4.0 14.5 8.0 15.1 1.7 0.7 9.6 2.1 1.5 13.4 47.2 6.2 24.0 15.0 2.9 5.4 16.5 47.3 16.6 29.4 28.9 11.3 20.6 24.5 31.4 20.3 9.1 24.4 19.4 17.5 39.5 17.4 17.5 49.5 26.6 4.2 0.2 20.2 29.0 1.4 1.1 21.4 2.1 6.4 15.5 30.1 21.7 101.5 42.5 14.2 77.8 9.7 8.1 37.4 14.1 54.1 41.7 11.7 8.1 26.4 34.8 14.5 31.8 8.4 5.9 3.0 42.0 21.2 13.0 30.7 20.2 22.9 42.8 19.1 21.1 59.3 24.8 36.1 23.1 0.0 0.2 0.1 0.8 0.2 0.3 0.3 1.1 1.3 0.7 1.0 0.3 0.6 0.6 1.5 0.1 0.0 5.2 0.6 3.7 8.3 9.0 7.7 3.2 5.4 9.9 8.1 8.8 7.4 8.0 13.4 7.5 6.4 1.7 0.7 3.0 4.2 1.6 2.3 6.8 2.9 5.9 8.9 2.5 0.0 1.9 1.8 6.2 7.2 7.2 12.3 0.0 0.2 6.9 1.3 2.7 3.5 0.0 33.6 2.3 0.2 7.8 2.6 4.1 2.9 0.0 2.1 2.5 1.3 4.4 8.4 2.6 4.0 0.0 2.5 1.9 9.0 1.2 4.8 0.0 0.0 0.0 1.0 1.0 1.5 34.5 0.2 2.4 0.4 14.6 1.1 6.3 0.1 1.1 4.7 6.6 2.6 4.3 77.7 26.2 9.5 3.8 1.9 7.5 1.2 3.3 0.8 CCNG1 CCNG ENSG00000113328 "Cyclin G1" P51959 5 163437569-163446151 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 265.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB000350 Supported Supported Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB000350: " "unprognostic (2.49e-2)" "unprognostic (1.64e-1)" "prognostic favorable (7.00e-4)" "unprognostic (2.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.26e-1)" "unprognostic (6.25e-2)" "unprognostic (1.58e-1)" "unprognostic (6.15e-2)" "unprognostic (1.45e-2)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.38e-3)" "unprognostic (1.46e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-1)" "unprognostic (7.89e-2)" 51.2 48.8 21.0 30.4 23.0 38.3 67.2 22.9 25.8 63.4 27.8 68.0 137.2 50.5 73.4 47.8 61.8 56.7 50.4 19.1 23.4 123.5 129.6 33.4 49.0 24.7 21.6 112.0 74.4 39.7 14.6 54.0 25.0 71.4 87.0 21.3 56.3 55.7 163.6 23.5 109.1 52.3 23.5 35.5 57.3 20.7 21.7 50.3 62.4 120.6 47.0 59.7 33.8 28.6 54.9 59.8 246.6 138.8 207.9 397.3 258.2 74.1 181.2 73.8 165.2 130.4 109.4 134.1 73.7 100.1 121.7 22.2 137.2 185.0 107.9 63.7 171.9 106.6 71.7 230.0 226.4 49.9 68.9 433.8 105.6 73.3 75.1 221.5 241.1 88.3 92.3 92.8 253.4 33.8 89.6 66.5 113.3 40.1 52.7 74.6 120.7 75.2 179.5 209.4 57.6 65.6 0.4 30.5 154.0 155.2 115.5 155.8 140.5 47.6 101.0 40.8 66.2 81.5 34.2 87.7 84.3 81.4 80.6 44.5 25.6 31.0 35.8 36.1 53.9 55.4 63.2 49.3 59.6 33.9 84.5 72.0 10.9 40.7 36.7 22.6 80.9 63.9 21.0 23.0 22.9 25.8 19.1 23.4 24.7 21.6 25.0 23.5 21.7 28.6 20.8 25.6 20.0 7.5 67.3 57.2 94.7 64.7 103.0 12.4 64.4 33.0 52.9 77.2 39.7 36.8 0.0 138.7 49.8 48.2 162.4 73.0 8.1 30.6 27.5 43.5 71.0 96.3 8.4 119.0 107.7 57.1 110.6 46.1 43.7 108.8 61.1 51.7 60.0 15.2 8.8 113.2 44.7 74.8 70.5 6.1 75.8 60.8 37.4 15.0 52.0 29.9 54.6 4.5 12.7 91.1 80.2 72.2 63.5 107.2 223.4 265.9 11.2 10.8 39.5 42.4 73.4 8.8 12.1 61.5 44.2 97.3 76.4 81.5 182.7 104.3 CCNG2 ENSG00000138764 "Cyclin G2" Q16589 4 77157207-77433388 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 56.1" HPA034684 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Cytosol" "HPA034684: AB_10669894" "unprognostic (2.58e-1)" "unprognostic (3.00e-1)" "unprognostic (1.46e-2)" "unprognostic (2.29e-1)" "unprognostic (5.73e-2)" "unprognostic (8.15e-2)" "unprognostic (8.40e-3)" "unprognostic (1.72e-2)" "unprognostic (1.20e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.57e-4)" "unprognostic (2.04e-1)" "prognostic favorable (2.47e-5)" "unprognostic (7.98e-2)" "unprognostic (2.20e-1)" "unprognostic (2.28e-1)" "unprognostic (1.05e-3)" 46.4 23.6 15.5 35.6 18.2 88.0 81.5 64.3 20.8 39.6 8.3 33.5 28.0 39.2 26.7 136.0 18.8 32.8 14.9 17.5 11.4 71.0 11.0 26.3 73.5 13.5 14.7 37.4 14.7 46.3 8.8 64.6 13.5 78.1 34.4 81.2 34.3 31.4 12.3 29.2 25.1 33.8 13.1 48.1 25.4 11.2 15.2 67.3 53.2 34.4 73.5 53.5 37.1 19.2 30.9 3.9 66.5 35.5 43.1 54.9 45.0 25.4 72.6 19.4 36.0 4.6 43.8 61.7 40.0 23.7 18.4 21.7 17.6 83.8 37.2 43.2 11.8 5.2 18.1 9.1 22.4 9.3 62.1 46.9 40.8 9.1 19.9 64.6 29.4 35.9 3.0 36.7 36.0 12.0 42.9 19.7 6.8 15.0 4.1 24.3 64.8 4.1 121.9 84.1 17.7 56.1 30.0 46.7 18.0 39.4 34.9 13.8 27.6 26.3 26.0 19.1 4.2 26.9 21.9 43.8 18.4 14.4 13.4 14.8 1.7 21.0 0.9 2.7 2.1 3.2 1.3 1.0 1.9 6.3 1.0 0.6 8.0 2.1 3.1 2.8 6.1 0.8 15.5 18.2 64.3 20.8 17.5 11.4 13.5 14.7 13.5 13.1 15.2 19.2 25.0 12.8 12.3 14.7 55.8 37.1 29.0 27.8 113.8 112.4 101.1 53.6 4.7 8.6 25.4 55.2 22.9 29.7 35.5 57.6 86.1 33.7 0.8 50.4 44.6 35.7 16.7 1.7 13.8 19.6 98.7 61.5 18.3 107.7 39.3 20.3 35.3 3.9 32.3 25.2 26.7 38.0 50.8 45.3 56.7 2.3 27.7 35.8 56.9 10.3 61.8 28.4 17.5 17.1 13.9 49.2 24.6 27.4 20.5 74.3 29.6 70.9 15.3 46.8 65.7 61.3 41.5 9.2 10.1 40.8 26.7 15.7 31.1 17.1 16.1 57.8 CCNH "CycH, p34, p37" ENSG00000134480 "Cyclin H" P51946 5 87318416-87412930 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 281.5;Plasma cells: 219.9;Spermatocytes: 202.6;T-cells: 207.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019416, HPA044138" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB019416: AB_2259936, HPA044138: AB_2678828" "unprognostic (5.65e-2)" "unprognostic (3.94e-3)" "unprognostic (4.01e-3)" "unprognostic (4.12e-1)" "unprognostic (1.10e-1)" "unprognostic (9.30e-2)" "unprognostic (3.93e-2)" "unprognostic (6.43e-2)" "unprognostic (8.79e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (4.16e-2)" "unprognostic (2.27e-2)" "prognostic unfavorable (3.92e-5)" "unprognostic (1.48e-1)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (9.62e-2)" 36.6 26.6 6.9 18.8 7.6 38.3 29.0 15.6 10.9 19.4 6.9 16.0 17.6 14.9 24.2 17.7 17.6 24.6 22.0 8.7 9.0 24.5 37.5 25.8 24.1 7.7 6.3 26.9 23.0 29.9 27.1 15.6 6.9 26.5 19.9 11.4 20.4 18.4 29.1 15.4 16.6 15.6 7.1 18.4 17.6 54.1 6.7 36.8 26.9 22.6 25.9 27.3 18.3 10.3 62.6 26.6 27.1 18.1 39.3 27.5 28.1 44.4 54.8 73.8 101.2 46.7 35.0 40.5 15.8 66.4 77.7 31.1 32.5 67.5 68.4 42.9 39.9 73.1 44.8 46.4 69.3 61.9 57.6 37.0 25.4 38.6 93.8 37.8 65.6 38.7 50.0 70.7 61.7 35.1 42.4 49.5 11.6 15.7 99.4 34.5 63.3 60.9 62.5 32.8 27.8 18.1 23.3 21.7 53.8 16.3 51.7 46.8 45.6 70.9 29.3 41.9 39.4 25.1 23.9 63.4 45.6 55.7 33.6 49.3 37.7 58.8 26.4 47.2 37.4 36.7 35.4 34.8 44.5 32.0 34.4 36.2 28.0 35.4 50.2 26.1 44.8 36.9 6.9 7.6 15.6 10.9 8.7 9.0 7.7 6.3 6.9 7.1 6.7 10.3 67.5 35.3 33.7 15.0 111.2 37.3 64.3 55.1 40.5 29.0 30.1 24.3 13.2 20.0 37.7 18.4 16.7 21.0 154.2 14.7 41.1 40.1 281.5 28.0 25.2 37.6 24.0 33.7 28.3 34.5 25.6 52.5 41.3 24.2 57.1 19.9 30.0 19.9 45.3 18.5 43.7 15.2 36.7 67.9 73.4 41.4 29.5 125.2 48.0 20.6 25.5 44.9 41.2 20.1 23.5 31.1 15.8 25.2 219.9 31.7 27.0 53.8 34.4 32.9 52.6 43.3 120.0 202.6 48.3 22.3 34.5 30.1 207.8 35.7 19.4 41.0 CCR10 GPR2 ENSG00000184451 "C-C motif chemokine receptor 10" P46092 17 42678889-42683917 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.2" "Cell type enhanced" "Detected in many" "B-cells: 14.1;Bipolar cells: 12.8;Plasma cells: 62.7;Sertoli cells: 19.7;Smooth muscle cells: 16.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "plasmacytoid DC: 24.7;T-reg: 72.4" "Group enriched" "Detected in many" 8 "dendritic cells: 24.7;T-cells: 72.4" "Cell line enhanced" "Detected in some" "Karpas-707: 8.4;RPMI-8226: 6.5;U-266/70: 17.1;U-266/84: 8.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB011684, HPA048007, HPA069188" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011684: AB_731502, HPA048007: AB_2680232, HPA069188: AB_2686100" "unprognostic (3.25e-2)" "unprognostic (2.71e-2)" "unprognostic (5.70e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (2.23e-3)" "unprognostic (5.18e-4)" "unprognostic (1.15e-1)" "unprognostic (9.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.21e-3)" "unprognostic (1.01e-2)" "unprognostic (2.32e-11)" "unprognostic (2.84e-2)" "unprognostic (1.53e-1)" "unprognostic (1.88e-2)" "unprognostic (1.87e-1)" 4.5 2.1 1.1 0.7 1.1 0.2 5.2 3.1 2.7 6.6 0.0 4.8 1.8 8.5 0.3 0.8 8.5 0.2 4.4 0.7 6.5 2.8 0.8 4.1 0.3 3.9 4.6 6.2 2.3 0.0 20.2 0.7 6.6 3.8 0.2 0.7 2.2 0.6 4.7 1.5 3.1 0.5 1.0 3.2 2.6 4.0 4.0 0.2 2.8 0.4 0.0 2.4 3.2 1.2 0.5 0.8 0.8 4.7 0.3 0.7 1.1 1.7 0.5 0.2 0.4 0.7 0.3 0.1 0.3 0.3 1.6 0.8 0.0 0.1 0.1 2.0 1.2 0.0 3.2 0.4 0.6 0.0 0.3 0.7 0.0 0.3 0.0 0.5 0.1 0.3 2.6 8.4 0.0 0.3 0.1 2.4 0.6 0.0 1.2 0.6 0.1 6.5 1.1 0.0 0.7 1.0 0.4 0.0 0.2 0.3 0.8 0.9 1.9 2.1 0.5 0.7 0.2 17.1 8.4 2.5 1.3 0.6 0.9 0.0 0.6 0.2 0.4 0.1 0.3 5.3 10.9 5.4 0.4 5.9 1.3 1.8 0.2 0.2 0.4 24.7 72.4 1.5 1.1 1.1 3.1 2.7 0.7 6.5 3.9 4.6 6.6 1.0 4.0 1.2 7.3 0.0 0.0 0.7 14.1 0.8 0.3 0.4 0.6 12.8 1.0 1.3 2.1 0.0 0.1 0.0 0.0 0.2 0.6 0.0 3.9 0.3 0.5 1.6 2.9 2.9 1.8 0.0 5.1 0.5 0.3 5.4 1.5 0.9 0.0 0.6 2.2 0.2 1.9 1.7 4.6 0.6 2.0 2.5 3.7 2.5 5.6 1.2 5.4 0.0 3.8 2.5 2.1 1.0 1.3 0.3 0.1 2.6 62.7 0.3 0.2 0.7 1.0 3.2 19.7 2.3 16.7 1.6 2.1 0.3 0.3 0.0 2.9 1.9 0.7 0.1 CCR7 "BLR2, CD197, CDw197, CMKBR7, EBI1" ENSG00000126353 "C-C motif chemokine receptor 7" P32248 17 40553769-40565472 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;lymphoid tissue: 84.0" "Group enriched" "Detected in many" 4 "Langerhans cells: 415.0;monocytes: 1586.1;Syncytiotrophoblasts: 517.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 4597.2" "Lineage enriched" "Detected in all" 4 "T-cells: 4597.2" "Cell line enriched" "Detected in some" 82 "HDLM-2: 1386.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003796, HPA031383, HPA074467" Enhanced Enhanced Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "CAB003796: AB_562261, HPA031383: AB_2673854, HPA074467: AB_2686693" "prognostic favorable (3.84e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.26e-3)" "unprognostic (1.32e-3)" "unprognostic (2.35e-3)" "prognostic favorable (7.61e-7)" "unprognostic (2.71e-4)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "unprognostic (4.68e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-1)" "unprognostic (1.08e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.02e-1)" "unprognostic (7.95e-2)" 4.6 0.6 0.0 67.2 0.3 15.2 2.3 0.0 0.2 2.7 0.6 3.6 1.2 1.6 0.0 2.0 3.9 5.1 2.5 0.1 0.0 2.1 2.3 2.7 84.0 0.2 0.1 1.8 0.6 0.1 1.4 1.1 0.2 1.9 5.1 0.5 1.8 0.3 0.5 2.2 21.3 0.9 0.0 28.6 5.3 1.9 0.2 58.8 2.8 0.4 83.3 8.8 2.0 0.8 0.4 1.5 0.0 0.0 0.0 0.3 16.8 0.4 0.1 0.0 0.0 0.2 0.0 0.6 0.9 0.0 0.1 0.2 0.0 0.0 0.0 1386.6 0.1 0.0 0.2 0.5 0.0 3.9 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.3 0.8 0.2 0.0 0.4 1.2 3.0 0.1 0.0 0.0 4.5 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.2 1.0 0.6 1.6 0.0 0.4 0.1 1.6 0.7 7.5 0.9 9.0 1.9 0.1 0.0 25.6 6.5 4.2 61.1 3.5 69.2 794.6 996.2 285.4 4.2 1122.5 4597.2 2462.0 45.3 970.9 6.4 58.5 637.3 2489.9 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.8 1.2 0.0 3.7 0.0 201.4 5.0 1.5 0.0 0.0 0.0 0.7 0.4 0.3 0.0 1.3 1.8 0.0 143.8 9.5 0.0 0.0 0.6 0.3 0.5 0.3 1.0 0.0 0.4 0.0 8.3 24.2 1.6 1.1 0.4 2.5 0.0 0.4 0.0 12.8 0.0 0.0 0.0 0.0 0.0 415.0 0.2 0.0 75.7 16.0 0.0 1586.1 0.4 3.1 0.0 0.1 0.5 0.0 0.0 3.6 0.2 0.0 0.3 0.0 0.0 0.0 0.2 2.4 0.6 0.8 0.0 4.4 517.6 75.2 0.1 0.0 4.6 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD1D ENSG00000158473 "CD1d molecule" P15813 1 158178030-158186427 "Cancer-related genes, CD markers, Predicted membrane proteins" "Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 18.2;liver: 15.3;lymphoid tissue: 23.9" "Cell type enhanced" "Detected in many" "B-cells: 22.2;Kupffer cells: 54.6;Macrophages: 40.8;monocytes: 45.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 139.0;intermediate monocyte: 63.8;myeloid DC: 139.3" "Group enriched" "Detected in many" 8 "dendritic cells: 139.3;monocytes: 139.0" "Cell line enhanced" "Detected in some" "HHSteC: 10.2;JURKAT: 49.4;MOLT-4: 13.6;THP-1: 8.8" "Low region specificity" "Detected in all" "CAB016107, HPA072662" Enhanced Supported "Endoplasmic reticulum" NA NA 880000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "CAB016107: AB_626960, HPA072662: AB_2686545" "unprognostic (8.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (3.85e-1)" "unprognostic (9.67e-3)" "unprognostic (2.37e-1)" "unprognostic (3.52e-1)" "unprognostic (2.23e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (9.31e-3)" "unprognostic (2.35e-1)" "unprognostic (2.32e-2)" "unprognostic (3.38e-1)" 2.7 2.0 0.1 7.5 0.2 3.1 2.0 0.1 0.4 1.5 0.7 4.4 7.4 2.2 0.5 0.8 2.1 1.8 3.3 0.1 0.2 2.2 15.3 3.4 4.7 0.3 0.2 0.6 1.9 0.3 1.0 0.4 0.3 2.2 2.9 0.3 1.1 0.7 1.1 0.3 18.2 2.3 0.1 23.9 2.3 2.5 0.2 9.4 2.7 0.6 3.0 1.8 1.0 0.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.0 0.0 3.5 0.0 6.0 0.0 0.0 0.1 0.2 0.0 0.0 10.2 0.1 0.0 3.9 0.6 0.0 0.7 0.0 0.0 49.4 0.0 0.0 0.0 0.0 13.6 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 8.8 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.3 0.0 3.7 0.4 0.2 139.0 0.4 0.2 63.8 0.5 17.6 0.1 0.1 139.3 13.4 0.1 0.0 7.2 0.3 11.0 1.4 0.2 80.7 0.1 0.2 0.1 0.4 0.1 0.2 0.3 0.2 0.3 0.1 0.2 0.4 9.4 0.0 3.6 0.0 22.2 0.3 0.5 0.8 0.6 0.7 0.1 0.9 0.7 2.8 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.4 5.6 0.4 2.0 2.4 2.4 1.7 0.0 0.0 0.2 0.5 0.0 0.3 1.3 0.1 3.3 6.3 11.3 1.7 0.2 2.0 0.0 54.6 0.8 2.1 0.0 40.8 0.0 0.0 45.4 0.6 1.0 0.0 0.0 0.0 6.4 0.0 3.7 0.1 7.3 0.1 0.0 0.3 0.0 1.2 0.4 1.0 2.1 0.0 0.1 0.1 0.6 0.1 4.5 0.1 CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1630.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1572.7;Distal tubular cells: 1590.6;Exocrine glandular cells: 3454.1;Glandular and luminal cells: 1441.8;Pancreatic endocrine cells: 1694.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28 "eosinophil: 86.2;memory B-cell: 61.1;naive B-cell: 39.7" "Group enriched" "Detected in many" 237 "B-cells: 61.1;granulocytes: 86.2" "Cell line enhanced" "Detected in many" "NTERA-2: 989.4;RPTEC TERT1: 4702.6;RT4: 931.5;SK-BR-3: 1352.5" "HPA045879, CAB078471" Approved Enhanced Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "CAB078471: AB_10983158, HPA045879: AB_2732523" "prognostic unfavorable (2.44e-5)" "unprognostic (6.64e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.87e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (7.58e-4)" "unprognostic (2.32e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.28e-2)" "unprognostic (1.51e-1)" "unprognostic (5.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" "unprognostic (3.13e-1)" 7.1 61.9 23.3 139.1 28.8 704.5 468.1 6.4 30.0 288.0 36.7 1071.8 89.0 181.5 229.6 1456.5 242.9 874.3 5.1 45.0 29.2 775.6 30.2 61.6 77.8 26.6 26.0 2.2 1383.4 2.5 12.5 151.7 17.2 148.8 740.8 2.6 952.4 546.9 1.4 77.2 69.8 117.7 19.5 29.6 601.7 4.9 38.6 15.2 1630.2 1.1 445.0 168.9 468.3 50.7 363.2 225.2 3.9 28.6 0.7 0.3 405.8 0.4 2.6 2.0 1.2 3.3 1.9 35.4 106.0 0.1 14.6 730.6 124.1 275.6 1.5 1.0 1.7 1.0 254.2 16.3 0.2 5.1 1.8 2.1 316.1 3.6 18.0 16.9 1.6 1.4 8.3 0.8 6.6 465.6 2.4 2.6 989.4 800.1 85.6 846.8 0.5 3.5 4702.6 931.5 612.4 448.7 250.0 1352.5 1.4 437.1 635.6 2.1 1.6 0.8 4.0 3.1 11.8 1.0 2.0 475.2 5.0 2.9 1.6 0.3 0.1 86.2 0.0 0.0 0.0 61.1 0.0 0.0 0.0 39.7 0.0 0.1 2.1 0.1 0.3 0.1 0.0 2.0 23.3 28.8 6.4 30.0 45.0 29.2 26.6 26.0 17.2 19.5 38.6 50.7 10.2 157.0 83.5 0.7 157.5 0.0 70.4 0.0 7.4 5.8 1109.4 325.4 1.5 1112.3 98.4 1302.1 2.1 749.2 13.7 1572.7 1590.6 1274.1 22.5 1237.6 254.2 38.6 575.4 5.3 0.6 3454.1 885.0 29.9 567.2 1441.8 10.8 0.6 97.5 9.7 70.8 0.0 5.7 463.6 0.0 7.6 0.0 53.4 10.2 17.6 0.0 1.0 32.6 1.0 0.0 0.0 0.1 1694.3 865.2 2.2 1.0 810.2 12.3 538.5 376.8 0.7 6.6 2.9 18.1 0.6 7.2 587.7 0.0 558.3 28.1 0.0 932.8 1043.7 CD27 "S152, TNFRSF7, Tp55" ENSG00000139193 "CD27 molecule" P26842 12 6444955-6451718 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 147.8" "Group enriched" "Detected in many" 11 "B-cells: 119.4;Melanocytes: 97.8;Plasma cells: 352.1;T-cells: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in all" "T-reg: 640.4" "Group enriched" "Detected in all" 7 "B-cells: 293.4;T-cells: 640.4" "Group enriched" "Detected in some" 107 "Daudi: 238.2;U-698: 141.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002420, HPA038936" Enhanced NA NA 100000 "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB002420: AB_563539, HPA038936: AB_2676278" "unprognostic (2.75e-3)" "prognostic favorable (3.77e-5)" "unprognostic (8.87e-3)" "prognostic favorable (2.90e-4)" "unprognostic (2.35e-1)" "prognostic favorable (6.65e-7)" "unprognostic (3.56e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.50e-4)" "unprognostic (1.31e-3)" "unprognostic (4.32e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (2.80e-1)" "unprognostic (3.15e-1)" "unprognostic (1.28e-1)" "unprognostic (7.35e-2)" 2.1 2.6 0.3 59.0 0.5 10.6 4.3 0.0 0.5 2.4 0.1 18.0 22.5 1.7 1.0 10.2 1.9 11.0 3.9 0.1 0.1 1.3 2.0 8.2 147.8 0.5 0.2 3.0 1.4 0.0 0.3 0.4 0.8 2.5 11.6 0.4 12.3 1.4 0.6 1.9 34.5 1.6 0.2 73.8 16.6 0.9 0.4 44.7 6.5 0.7 106.3 19.0 1.4 1.0 0.2 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 238.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.5 0.8 0.0 0.0 1.7 0.0 0.7 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.5 0.1 0.0 0.0 0.0 141.7 0.3 0.1 0.0 6.2 1.6 1.4 117.2 1.3 201.2 293.4 283.5 262.6 1.0 114.8 382.8 281.1 6.2 65.0 1.6 2.4 640.4 182.4 0.3 0.5 0.0 0.5 0.1 0.1 0.5 0.2 0.8 0.2 0.4 1.0 1.1 0.0 4.9 0.3 119.4 2.3 0.1 0.0 0.6 1.1 1.1 1.3 0.1 0.0 0.6 0.0 0.0 0.1 7.0 0.3 0.0 0.2 0.0 0.2 0.3 0.9 1.2 8.4 0.2 0.0 0.0 1.5 3.1 0.3 1.3 0.0 2.5 1.5 0.3 0.0 0.3 0.1 0.0 3.2 4.4 0.3 0.3 3.0 97.8 0.0 5.7 0.4 14.4 1.0 1.0 0.0 0.1 0.4 352.1 0.2 0.0 0.9 0.8 1.4 0.0 0.7 1.3 0.1 0.1 0.6 3.1 0.3 109.5 0.0 2.4 0.0 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1533.6" "Cell type enhanced" "Detected in many" "Adipocytes: 3219.2;Cardiomyocytes: 623.1;Hofbauer cells: 1369.8;Sertoli cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 962.6;intermediate monocyte: 270.6;myeloid DC: 507.1" "Group enriched" "Detected in all" 46 "dendritic cells: 507.1;monocytes: 962.6" "Group enriched" "Detected in some" 4 "ASC diff: 322.6;HEL: 158.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 16.9" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" 1533.6 24.6 3.4 51.7 2.5 148.2 540.4 1.6 2.0 11.6 2.7 40.5 113.6 8.7 38.2 19.6 40.5 84.0 540.9 2.6 6.9 7.0 80.8 131.2 18.8 22.0 21.2 4.0 31.2 25.0 2.0 413.3 15.7 5.0 40.9 0.3 31.9 8.6 248.5 28.6 119.7 39.4 14.0 309.9 31.2 7.7 24.0 22.1 69.1 381.6 7.2 22.2 13.4 3.9 0.0 0.0 1.0 0.2 322.6 3.3 0.7 0.9 10.7 0.1 0.1 0.0 0.0 0.1 0.6 1.4 0.3 0.1 4.3 0.5 0.1 0.6 0.4 158.1 0.5 25.7 0.2 0.1 0.1 31.0 12.6 0.1 0.2 7.7 0.9 0.0 5.8 0.0 1.8 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.5 0.5 0.1 0.9 1.3 0.8 0.6 0.3 2.7 11.1 19.3 0.4 0.5 0.5 0.6 0.3 0.2 0.8 0.4 0.1 54.3 41.8 12.3 962.6 3.7 1.9 270.6 2.1 3.6 0.6 0.6 507.1 0.5 0.8 0.4 15.8 5.9 72.0 128.3 1.5 692.4 3.4 2.5 1.6 2.0 2.6 6.9 22.0 21.2 15.7 14.0 24.0 3.9 3219.2 6.4 63.1 0.0 7.9 7.4 0.2 3.0 0.6 0.2 189.9 24.8 623.1 4.3 9.8 7.3 0.0 10.1 55.0 0.0 0.0 0.2 11.7 5.0 5.9 303.3 0.0 419.5 6.3 0.0 11.1 69.6 1.1 38.4 15.2 0.6 406.2 9.0 1369.8 0.0 2.2 0.6 8.2 153.7 67.3 3.9 0.6 159.6 16.0 17.8 255.2 0.0 7.2 0.5 1.3 0.1 0.0 0.0 4.2 0.8 9.9 0.4 1.2 0.3 696.8 33.1 452.1 4.6 0.7 0.8 4.7 18.3 5.9 1.9 0.2 0.3 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853232 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.3" "Cell type enriched" "Detected in many" 4 "Plasma cells: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 18.3" "Group enriched" "Detected in all" 5 "B-cells: 9.9;dendritic cells: 5.8;NK-cells: 18.3" "Cell line enhanced" "Detected in some" "Daudi: 128.0;Karpas-707: 34.7;MOLT-4: 32.6;REH: 26.0;RPMI-8226: 20.9;U-266/70: 26.9;U-698: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favorable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 3.1 2.4 2.5 13.1 3.8 13.6 2.0 2.7 2.5 0.7 0.9 4.5 5.8 0.9 1.2 1.1 3.0 1.9 3.8 3.5 6.6 0.8 3.3 6.3 23.4 3.3 5.5 0.7 0.3 0.1 1.8 0.5 3.4 13.2 3.5 0.2 2.6 19.7 21.4 0.3 5.3 1.4 2.8 17.0 3.0 1.0 3.9 63.3 2.0 3.4 18.0 6.8 0.5 4.6 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 128.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 17.0 0.2 34.7 0.0 0.0 32.6 7.9 0.2 0.0 0.0 26.0 0.1 20.9 0.0 0.0 0.2 1.5 0.0 0.2 0.5 0.3 0.1 5.7 0.5 0.0 0.1 0.1 0.0 26.9 0.2 24.3 0.4 6.2 0.3 0.1 1.9 0.1 1.2 2.4 0.3 9.9 1.5 1.2 4.7 7.7 2.4 1.9 1.4 18.3 1.9 5.8 2.4 4.4 2.5 3.8 2.7 2.5 3.5 6.6 3.3 5.5 3.4 2.8 3.9 4.6 0.8 3.2 15.1 86.5 59.7 0.0 0.4 0.6 0.6 0.1 0.1 0.0 1.0 0.0 11.6 0.0 10.4 0.2 33.8 0.2 0.0 0.0 2.5 4.0 1.4 2.7 0.0 78.6 0.4 0.0 0.2 2.7 2.0 0.3 38.2 0.8 2.9 4.3 4.4 0.0 0.4 1.3 0.0 44.3 0.8 0.7 0.0 17.7 7.2 5.6 3.1 0.0 79.3 1.0 1.8 0.0 0.3 0.0 378.4 8.1 0.2 0.1 42.5 0.1 13.1 1.5 7.6 2.9 1.7 1.6 0.0 0.5 26.5 0.0 1.6 0.2 CD40 "Bp50, p50, TNFRSF5" ENSG00000101017 "CD40 molecule" P25942 20 46118278-46129863 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 127.5;Basal respiratory cells: 126.0;Langerhans cells: 191.4;monocytes: 242.0;Prostatic glandular cells: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 139.4;naive B-cell: 157.9" "Group enriched" "Detected in all" 6 "B-cells: 157.9;monocytes: 43.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 76.0;Daudi: 42.1;EFO-21: 131.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002495, HPA031567, HPA031568, CAB072868" Enhanced "Secreted to blood" NA NA 705000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "CAB002495: AB_563562, CAB072868: AB_2665719, HPA031567: AB_2673936, HPA031568: AB_2673937" "unprognostic (6.41e-2)" "unprognostic (1.55e-2)" "unprognostic (7.08e-3)" "unprognostic (6.21e-2)" "unprognostic (4.23e-3)" "unprognostic (1.25e-1)" "unprognostic (7.64e-3)" "unprognostic (1.34e-1)" "unprognostic (4.15e-2)" "unprognostic (7.16e-2)" "unprognostic (2.48e-2)" "unprognostic (7.04e-2)" "prognostic unfavorable (4.48e-4)" "unprognostic (1.22e-1)" "unprognostic (4.95e-2)" "unprognostic (1.60e-2)" "unprognostic (2.28e-2)" 25.9 8.4 6.7 34.9 7.0 2.7 20.5 7.6 7.7 19.4 9.4 11.8 12.6 14.4 7.6 12.4 19.7 14.3 16.3 6.6 7.2 26.1 18.3 34.4 57.8 8.0 7.1 24.5 21.9 46.5 9.9 12.4 7.6 23.6 9.6 1.1 24.5 15.4 8.6 17.0 21.8 14.0 7.8 35.1 15.6 3.8 7.3 17.3 20.4 7.1 57.7 32.9 21.0 8.0 26.6 4.1 0.0 12.8 4.7 2.7 5.0 4.9 1.4 3.8 3.6 0.0 76.0 42.1 131.8 0.8 18.7 3.1 2.3 16.2 3.9 29.0 0.0 10.0 0.0 7.5 36.6 0.0 13.0 16.2 6.2 15.3 0.0 0.0 28.3 0.0 3.5 0.0 0.8 0.0 0.0 0.2 1.8 9.3 0.1 1.1 1.0 4.5 32.7 0.3 0.0 0.0 23.1 12.6 0.0 0.0 2.7 14.5 0.0 0.0 41.2 0.0 0.1 0.1 0.1 29.2 9.6 5.0 0.1 4.0 28.0 0.4 4.8 43.3 3.5 139.4 2.6 2.0 16.1 157.9 5.0 3.7 2.8 2.9 32.1 8.3 4.1 20.0 6.7 7.0 7.6 7.7 6.6 7.2 8.0 7.1 7.6 7.8 7.3 8.0 68.8 12.8 15.0 6.5 127.5 43.6 63.3 126.0 30.1 1.2 3.8 10.0 3.9 30.0 32.9 14.7 0.0 0.4 7.3 1.5 0.0 68.4 9.0 1.3 2.4 61.5 1.2 5.2 0.9 29.7 3.2 37.9 11.7 3.3 3.8 0.6 55.3 17.0 40.5 0.0 0.9 6.2 14.2 13.0 191.4 14.6 25.7 48.1 28.4 12.2 242.0 9.0 6.2 0.5 0.2 37.9 8.8 22.6 25.1 130.2 6.1 4.3 12.2 0.4 32.9 28.0 31.6 1.9 5.7 13.2 34.1 0.4 4.8 2.3 6.8 64.4 CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 8 "T-cells: 76.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cell line enriched" "Detected in some" 15 "MOLT-4: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" 0.8 0.3 0.1 7.9 0.0 1.9 1.1 0.2 0.2 0.9 0.2 1.9 1.8 0.3 0.2 1.0 0.4 2.0 0.2 0.1 0.2 0.4 1.0 2.4 15.5 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.8 3.1 0.0 0.6 0.3 0.1 0.6 3.8 0.6 0.0 4.9 2.0 0.3 0.1 15.5 0.5 0.2 14.8 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.3 26.3 0.1 64.1 0.1 80.5 11.7 0.2 0.0 76.1 0.7 1.3 0.8 0.1 0.1 10.5 13.6 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.0 2.4 0.0 2.4 1.3 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.6 2.6 0.0 1.3 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 4.0 8.9 0.0 2.9 1.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.1 2.0 0.0 76.6 0.0 0.0 0.1 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD46 "MCP, MGC26544, MIC10, TLX, TRA2.10" ENSG00000117335 "CD46 molecule" P15529 1 207752054-207795513 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Complement pathway, Fertilization, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 296.7;eosinophil: 382.4;neutrophil: 401.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 401.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB010401, HPA016903" Enhanced Approved "Plasma membrane" NA NA 1000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB010401: AB_2291289, HPA016903: AB_1846309" "unprognostic (1.42e-2)" "prognostic unfavorable (8.54e-5)" "unprognostic (3.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-1)" "unprognostic (8.79e-2)" "unprognostic (2.50e-1)" "unprognostic (6.78e-3)" "prognostic favorable (2.38e-4)" "unprognostic (1.76e-1)" "unprognostic (8.23e-2)" "unprognostic (1.49e-2)" 98.6 237.4 30.0 64.0 35.0 80.5 128.4 33.5 39.5 74.0 61.4 103.1 124.6 62.1 77.1 102.2 110.0 73.8 64.9 30.2 34.4 173.2 133.9 129.1 58.2 37.4 33.6 61.2 112.5 310.6 41.8 221.5 38.1 167.4 103.2 72.6 166.9 107.4 47.4 47.7 98.6 67.1 34.8 79.6 117.4 40.5 36.3 44.4 86.8 58.1 66.6 97.2 68.2 41.5 130.0 71.7 66.1 30.8 202.9 199.2 99.9 95.0 137.3 61.3 82.5 71.3 335.4 19.8 94.3 95.3 84.5 170.7 50.0 130.5 93.0 99.9 70.9 42.9 73.8 128.6 128.8 94.8 142.8 172.9 189.6 92.9 72.5 144.4 174.2 76.8 91.8 83.4 95.7 61.3 45.4 82.8 75.6 76.9 70.9 30.2 104.7 123.0 251.4 252.6 66.5 45.4 120.5 266.8 160.1 130.8 210.2 79.8 150.9 65.6 57.7 139.2 109.9 111.2 144.3 60.1 95.8 61.2 63.0 296.7 79.8 382.4 50.1 82.4 68.9 43.5 63.3 55.8 47.3 34.1 71.1 60.5 401.8 46.9 87.5 24.9 60.5 102.4 30.0 35.0 33.5 39.5 30.2 34.4 37.4 33.6 38.1 34.8 36.3 41.5 186.0 201.9 241.1 59.7 60.3 52.9 89.3 87.2 108.1 63.0 144.3 85.7 61.4 75.8 177.8 145.3 66.7 247.3 94.0 105.2 15.6 77.4 227.7 206.1 67.0 106.7 72.8 46.9 61.0 79.9 76.2 70.5 97.9 231.3 114.5 78.1 77.8 120.9 59.9 40.4 73.6 91.1 87.5 78.9 63.1 36.9 47.2 91.6 62.2 82.4 88.7 25.3 39.1 112.1 153.9 72.8 117.7 44.0 76.0 144.5 92.6 54.4 208.8 87.3 52.6 69.7 89.3 17.1 20.2 104.5 45.9 343.7 89.9 99.4 115.9 165.7 CD52 "CDW52, EDDM5, HE5" ENSG00000169442 "CD52 molecule" P31358 1 26317958-26320523 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "epididymis: 36173.0" "Cell type enhanced" "Detected in many" "B-cells: 1861.9;granulocytes: 568.6;Hofbauer cells: 562.6;Langerhans cells: 674.3;Macrophages: 690.5;monocytes: 814.2;NK-cells: 602.5;T-cells: 1300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Daudi: 708.6;REH: 1042.2;U-266/84: 1087.0;U-698: 1159.2" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "prognostic favorable (1.85e-5)" "unprognostic (3.28e-3)" "unprognostic (1.93e-2)" "prognostic favorable (2.06e-4)" "unprognostic (4.18e-2)" "prognostic favorable (4.45e-4)" "unprognostic (9.11e-2)" "unprognostic (2.98e-2)" "unprognostic (7.73e-3)" "unprognostic (6.27e-2)" "unprognostic (4.58e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.64e-1)" "unprognostic (6.14e-2)" "unprognostic (7.95e-2)" "unprognostic (1.26e-1)" 62.1 10.2 10.2 297.8 13.5 266.9 59.5 9.6 38.5 26.1 12.6 68.6 41.7 21.3 36173.0 35.0 18.4 89.2 18.0 10.3 10.0 18.7 55.0 449.2 1082.0 11.3 10.0 9.6 8.2 5.4 6.1 16.9 10.5 19.2 96.9 0.2 37.6 104.2 9.4 27.9 294.7 47.4 10.1 646.5 87.2 4.7 16.5 1051.6 24.9 13.8 1256.4 134.9 13.1 10.5 2.0 0.0 0.3 0.0 0.0 1.4 14.3 0.1 1.0 0.1 0.0 0.3 0.6 708.6 1.4 0.0 0.3 0.1 0.0 0.2 0.0 0.5 0.2 34.8 0.0 1.4 0.0 7.5 106.4 0.0 0.0 0.2 0.0 0.7 0.0 44.9 23.7 1.0 0.0 4.6 8.5 62.9 3.0 0.5 0.0 1042.2 0.9 16.6 0.0 0.0 2.1 9.3 0.4 1.1 1.3 9.2 0.3 12.5 1.6 0.0 2.7 0.7 1.2 2.9 1087.0 1159.2 0.1 17.8 0.1 599.3 4558.9 9769.3 6605.8 7389.3 5319.0 10570.4 8177.1 6530.7 3180.2 10064.7 5495.2 5664.3 334.5 3732.1 6667.9 1034.9 11684.0 22571.2 10.2 13.5 9.6 38.5 10.3 10.0 11.3 10.0 10.5 10.1 16.5 10.5 9.5 67.3 194.6 0.0 1861.9 45.4 0.8 0.2 3.4 0.0 8.4 5.8 6.2 14.3 50.1 49.7 0.0 4.7 415.9 1.9 0.0 1.3 0.8 3.9 2.6 29.5 0.0 60.6 0.3 0.2 5.8 18.1 29.6 7.1 568.6 0.0 17.5 3.6 562.6 0.0 0.1 2.3 0.0 262.6 674.3 1.4 0.0 690.5 106.7 1.9 814.2 0.0 602.5 0.0 0.1 0.2 2.8 0.0 133.7 3.1 0.7 11.5 17.5 0.0 0.0 7.3 9.1 0.3 0.5 3.2 31.4 5.6 1300.0 0.0 2.7 1.1 CD59 "16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20" ENSG00000085063 "CD59 molecule (CD59 blood group)" P13987 11 33703010-33736479 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1445.2;Prostatic glandular cells: 1678.0;Urothelial cells: 1531.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 3747.5;U-2197: 3049.9" "CAB001448, HPA026494" Supported Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 58000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Vesicles" "CAB001448: AB_563604, HPA026494: AB_1846321" "unprognostic (2.07e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (7.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (4.47e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (1.66e-2)" "prognostic favorable (1.39e-10)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (3.09e-1)" 517.4 248.3 284.5 209.6 310.8 198.8 555.9 329.0 365.1 305.5 542.2 255.1 120.7 290.7 971.7 478.9 368.1 475.3 608.3 288.2 359.7 577.4 339.8 553.5 148.8 327.9 340.2 228.5 353.6 706.1 250.3 485.6 340.9 256.8 271.4 130.7 693.6 443.2 529.3 282.8 167.9 380.0 330.5 131.8 422.7 127.7 337.0 167.7 308.1 915.0 288.6 550.5 325.5 315.6 297.2 278.4 77.6 212.0 1697.1 1314.9 46.8 1765.7 1778.5 408.9 451.9 129.7 822.1 23.9 291.5 1802.5 475.5 314.0 141.0 1589.9 561.1 475.5 218.2 31.3 846.7 193.1 483.2 183.4 94.8 631.8 387.2 343.3 1550.6 1104.9 2475.5 109.3 207.9 585.9 2575.4 282.7 79.9 70.3 43.5 541.8 1421.8 30.1 232.1 227.8 1304.4 510.0 54.3 79.5 576.2 243.7 298.2 218.0 187.5 18.1 3747.5 838.6 235.5 3049.9 595.9 273.8 558.8 30.4 734.2 1.3 1556.9 164.9 22.3 209.6 50.9 7.9 64.8 63.9 104.9 56.6 95.4 59.6 68.2 41.4 134.3 92.5 4.8 49.9 298.2 53.5 284.5 310.8 329.0 365.1 288.2 359.7 327.9 340.2 340.9 330.5 337.0 315.6 728.0 272.4 247.2 32.3 39.1 286.0 1103.2 951.4 82.0 51.3 434.9 270.0 315.5 444.7 569.7 242.8 33.3 553.5 29.2 344.6 164.4 1445.2 129.4 94.3 91.6 792.6 166.6 206.0 25.1 618.3 407.2 303.5 109.6 115.6 139.4 88.2 585.0 185.7 486.7 47.1 29.9 112.8 722.2 139.4 374.2 61.6 237.3 88.2 1270.0 54.4 161.7 198.3 26.8 32.6 22.2 1195.7 392.2 204.7 149.7 1678.0 41.7 208.2 1042.5 56.2 276.1 159.1 410.7 130.6 31.2 83.7 284.4 836.6 52.4 139.5 104.9 1531.0 CD70 "CD27L, CD27LG, TNFSF7" ENSG00000125726 "CD70 molecule" P32970 19 6583183-6604103 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 4 "monocytes: 239.4" "Cancer enriched" "Detected in many" 4 "renal cancer: 24.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 44.2" "Group enriched" "Detected in many" 35 "B-cells: 24.2;T-cells: 44.2" "Cell line enhanced" "Detected in many" "SiHa: 189.2;THP-1: 157.3;U-251 MG: 234.2;U-266/70: 399.5;U-266/84: 312.7;U-698: 138.1" "Region enriched" "Detected in single" 25 "cerebellum: 11.3" "Low region specificity" "Detected in all" HPA046582 Uncertain Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "HPA046582: " "unprognostic (8.71e-2)" "unprognostic (9.91e-2)" "unprognostic (1.61e-1)" "unprognostic (2.33e-4)" "unprognostic (1.73e-2)" "unprognostic (1.51e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (2.57e-2)" "unprognostic (1.40e-1)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" 2.4 0.1 0.1 3.2 0.1 0.8 1.1 0.5 0.3 0.4 0.3 2.2 0.5 0.1 0.0 0.7 0.2 0.4 0.1 0.1 0.2 0.5 0.2 0.8 3.4 0.2 0.2 0.1 0.3 0.0 0.1 0.1 0.2 0.2 1.5 0.0 0.2 0.0 0.3 1.4 2.2 0.1 0.0 2.9 1.0 0.3 0.1 1.5 0.3 0.9 1.9 1.1 0.5 0.4 1.3 39.1 0.1 75.6 1.7 1.0 0.1 0.0 0.3 0.3 2.6 0.1 0.5 74.2 4.1 0.4 81.8 53.2 46.5 3.6 0.0 0.2 1.6 0.0 56.8 0.1 0.0 0.0 2.2 0.5 0.4 43.9 31.1 12.2 0.3 0.1 1.3 2.5 1.1 0.2 1.3 94.3 0.9 0.0 70.0 20.3 0.1 16.3 24.6 0.2 0.0 0.0 189.2 0.0 0.8 0.2 0.5 157.3 1.0 0.6 32.6 0.0 234.2 399.5 312.7 138.1 41.0 23.8 14.8 0.8 0.1 0.1 3.3 0.0 8.1 24.2 5.3 8.8 0.1 9.9 0.7 2.1 0.2 0.9 0.0 0.3 44.2 1.6 0.1 0.1 0.5 0.3 0.1 0.2 0.2 0.2 0.2 0.0 0.1 0.4 0.6 0.0 0.0 0.0 50.9 5.7 0.1 11.1 0.0 0.0 0.1 0.3 0.2 0.0 0.3 1.8 0.0 0.0 2.3 0.0 0.0 0.3 0.0 0.4 0.0 1.6 1.8 0.0 0.1 0.7 0.0 11.3 0.5 0.2 1.3 0.1 0.7 0.3 0.4 0.0 0.7 0.0 18.3 0.6 14.6 0.0 0.0 3.0 3.6 0.0 239.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 24.9 0.2 0.0 0.2 0.7 0.0 0.0 0.4 0.9 0.2 0.6 0.4 5.4 0.0 14.1 0.0 0.4 0.0 CD74 DHLAG ENSG00000019582 "CD74 molecule" P04233 5 150400041-150412969 "Cancer-related genes, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 5258.9" "Cell type enhanced" "Detected in many" "B-cells: 10167.0;Kupffer cells: 5201.6;Langerhans cells: 23363.4;Macrophages: 7290.2;monocytes: 10305.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 11041.2;intermediate monocyte: 15961.1;memory B-cell: 26889.3;myeloid DC: 23750.6;naive B-cell: 27930.3;non-classical monocyte: 8003.3;plasmacytoid DC: 16940.0" "Group enriched" "Detected in all" 6 "B-cells: 27930.3;dendritic cells: 23750.6;monocytes: 15961.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 2171.7;Daudi: 3523.2;HDLM-2: 4787.6;REH: 3026.0;RPMI-8226: 2014.2;U-266/70: 1443.4;U-698: 1978.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002506, HPA010592, CAB079994" Enhanced Supported "Golgi apparatus" NA NA 210000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "CAB002506: AB_563630, CAB079994: , HPA010592: AB_1078482" "prognostic favorable (1.06e-4)" "unprognostic (1.48e-2)" "unprognostic (4.80e-3)" "prognostic favorable (6.53e-6)" "unprognostic (1.41e-1)" "unprognostic (4.53e-2)" "unprognostic (2.05e-1)" "unprognostic (3.69e-3)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (2.20e-2)" "unprognostic (2.64e-1)" "unprognostic (5.44e-3)" "unprognostic (1.73e-1)" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (4.24e-2)" 1512.1 976.5 338.1 2741.2 301.9 984.3 1157.2 365.5 474.4 1562.8 429.1 992.3 1826.2 593.6 490.6 618.8 1139.0 1477.9 604.0 306.7 506.8 1271.1 1142.0 3786.3 4995.6 598.7 431.8 464.3 392.4 390.6 469.3 305.7 533.4 556.7 1155.8 58.1 1999.3 911.8 307.2 682.4 2438.8 1014.2 514.2 4897.4 1511.5 207.5 514.4 2160.2 853.5 374.2 5258.9 1557.5 483.5 771.8 35.7 0.3 1.5 2.4 2.3 2.5 11.0 0.0 0.0 0.7 0.6 443.0 2171.7 3523.2 124.2 0.0 9.2 9.4 0.0 0.0 0.1 4787.6 0.0 109.1 1.2 250.2 6.6 9.2 6.5 24.5 0.0 0.8 0.0 0.6 0.0 0.0 8.0 1270.7 0.4 0.0 4.2 14.0 5.3 0.0 0.1 3026.0 5.2 2014.2 9.0 133.5 5.1 8.2 5.5 4.7 94.9 19.2 81.2 414.4 5.6 10.3 9.9 9.0 4.5 1443.4 170.7 1978.6 745.9 154.2 678.6 410.8 11041.2 3996.9 808.7 15961.1 899.9 26889.3 688.4 1188.4 23750.6 27930.3 378.9 646.6 839.6 2378.1 8003.3 16940.0 2157.2 17779.7 338.1 301.9 365.5 474.4 306.7 506.8 598.7 431.8 533.4 514.2 514.4 771.8 2080.4 419.9 2160.4 0.7 10167.0 715.9 154.0 762.2 398.4 1.7 220.3 437.5 69.6 401.7 1063.3 502.1 0.0 28.3 3199.0 139.7 117.4 1264.4 10.4 111.3 11.5 1787.6 242.9 562.5 0.7 527.5 32.6 278.6 538.2 85.5 417.2 113.4 514.7 52.5 4361.8 1.7 0.6 475.7 390.6 5201.6 23363.4 31.3 117.1 7290.2 1197.1 137.7 10305.9 16.8 403.7 0.5 1.4 384.2 487.3 17.7 2068.3 174.9 5034.4 815.8 1153.1 10.0 164.3 45.1 146.7 2.8 12.6 170.9 575.8 41.6 790.7 12.9 450.7 743.4 CD79A "IGA, MB-1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 152.3;lymphoid tissue: 545.2" "Group enriched" "Detected in some" 5 "B-cells: 1186.4;Plasma cells: 956.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "memory B-cell: 1273.8;naive B-cell: 1457.5" "Lineage enriched" "Detected in all" 40 "B-cells: 1457.5" "Group enriched" "Detected in some" 22 "Daudi: 1598.7;REH: 491.0;U-698: 1366.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000019, HPA056444" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB000019: AB_2244527, HPA056444: " "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" 4.8 4.9 0.2 213.4 0.2 47.2 9.5 0.2 0.4 3.6 0.1 47.3 37.9 2.4 1.4 9.9 1.8 13.0 2.9 0.1 0.1 3.4 2.6 8.9 482.4 0.3 0.2 3.7 0.6 0.1 0.3 1.2 0.2 4.3 28.9 0.0 28.5 2.2 0.7 0.4 152.3 2.2 0.6 286.5 76.9 2.4 0.2 93.7 8.1 0.4 545.2 32.3 1.9 0.3 1.1 0.8 0.3 0.1 0.2 0.7 0.2 0.2 0.0 0.3 0.0 0.0 0.1 1598.7 1.2 0.0 0.1 0.0 0.2 0.2 0.0 0.5 0.7 2.7 0.0 1.7 0.2 2.6 1.8 0.5 0.6 0.2 0.0 0.0 0.0 8.0 3.1 0.4 0.1 1.1 1.6 9.9 0.1 0.1 0.4 491.0 0.8 2.5 0.1 0.0 0.5 0.5 0.8 0.5 1.3 0.0 0.0 4.8 1.6 0.1 4.3 0.3 0.8 7.8 1.4 1366.7 0.0 52.1 0.1 12.4 1.5 6.9 1.7 1.8 0.7 1273.8 4.1 2.1 2.5 1457.5 4.9 26.3 4.6 2.6 4.3 36.3 10.4 62.7 0.2 0.2 0.2 0.4 0.1 0.1 0.3 0.2 0.2 0.6 0.2 0.3 0.2 0.0 2.4 0.0 1186.4 1.8 0.5 0.5 0.6 0.0 0.7 0.9 0.2 1.5 0.2 0.0 0.0 0.2 18.2 0.7 0.0 1.8 0.2 0.1 0.3 0.5 0.0 10.5 0.0 25.6 0.4 2.2 6.6 0.2 0.0 0.4 2.2 1.0 0.8 0.0 0.0 0.4 0.0 4.1 1.4 0.0 0.3 5.3 138.7 0.0 6.3 0.0 15.5 0.0 0.0 181.7 0.4 0.4 956.7 0.3 0.2 0.9 0.0 0.0 0.0 0.2 0.7 0.3 0.6 0.9 1.4 0.1 23.5 0.2 5.3 0.2 CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 266.7" "Cell type enriched" "Detected in many" 4 "B-cells: 491.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "memory B-cell: 1132.1;naive B-cell: 1505.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1505.8" "Cell line enhanced" "Detected in some" "Daudi: 1060.0;REH: 350.2;U-698: 1475.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" 5.0 1.7 0.9 70.5 0.9 54.6 3.4 0.9 1.4 1.9 1.7 7.7 4.7 1.4 1.6 2.6 1.5 6.8 12.3 0.9 0.9 4.7 3.4 4.9 266.7 1.0 0.9 0.6 0.7 0.7 25.3 3.8 0.9 2.5 7.2 0.0 7.8 0.8 3.4 2.4 66.2 2.6 0.9 147.7 10.7 1.0 1.0 27.1 4.1 5.8 208.4 13.4 2.2 1.0 1.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.4 0.0 0.0 1060.0 7.8 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.4 0.6 0.6 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.4 1.2 56.9 0.0 0.0 0.6 23.0 0.3 0.0 0.0 350.2 0.9 4.4 0.0 0.0 0.5 0.0 1.7 0.0 0.7 5.8 0.0 16.2 1.7 0.1 3.7 0.3 0.6 51.3 54.4 1475.5 0.0 2.2 0.0 6.2 13.0 1.1 44.9 192.2 51.3 1132.1 57.1 30.1 47.0 1505.8 38.4 23.2 5.8 42.4 304.3 6.7 107.9 112.1 0.9 0.9 0.9 1.4 0.9 0.9 1.0 0.9 0.9 0.9 1.0 1.0 24.9 0.0 1.3 0.0 491.9 4.5 0.4 0.0 1.8 0.0 1.1 4.4 1.4 1.5 0.0 0.0 0.0 0.2 24.2 0.3 0.0 0.1 0.6 0.3 1.0 25.2 1.2 8.6 0.0 0.0 0.4 3.3 0.5 0.3 15.2 0.0 51.4 1.3 5.8 0.0 0.0 0.4 0.0 14.8 5.1 1.4 1.2 13.4 21.4 0.0 14.3 0.0 36.0 0.0 0.0 0.0 0.1 1.9 99.6 0.4 0.0 1.0 0.0 0.0 0.0 4.4 5.4 1.2 0.3 0.7 3.1 0.4 27.0 0.5 0.8 0.2 CD82 "IA4, KAI1, R2, ST6, TSPAN27" ENSG00000085117 "CD82 molecule" P27701 11 44564427-44620358 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 280.3;Proximal enterocytes: 220.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 536.4" "Group enriched" "Detected in all" 6 "B-cells: 310.1;granulocytes: 536.4;T-cells: 173.1" "Cell line enhanced" "Detected in many" "HMC-1: 463.8;U-87 MG: 323.3" "Region enhanced" "Detected in all" "white matter: 210.9" "Low region specificity" "Detected in all" "CAB002508, HPA028900, HPA061418" Supported Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB002508: AB_563640, HPA028900: AB_10603558, HPA061418: AB_2684510" "unprognostic (5.31e-2)" "unprognostic (4.62e-1)" "unprognostic (2.38e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.29e-2)" "unprognostic (3.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.58e-2)" "unprognostic (1.58e-1)" "unprognostic (3.48e-3)" "unprognostic (1.86e-3)" "unprognostic (2.33e-2)" "unprognostic (2.88e-2)" "unprognostic (6.30e-2)" 39.2 9.1 47.7 57.3 80.5 140.9 36.6 45.2 48.8 38.8 48.5 24.7 74.1 9.1 31.9 130.9 54.0 39.6 25.6 41.9 51.7 26.1 36.9 87.3 68.5 58.5 74.3 14.9 31.3 7.8 7.5 41.0 49.8 27.5 17.2 4.2 81.1 72.1 23.1 84.2 81.6 16.6 39.6 47.3 62.8 4.5 79.0 45.0 22.4 20.0 82.6 47.6 66.1 67.2 30.0 5.2 35.1 7.2 24.0 98.4 1.2 16.9 132.9 29.4 78.5 2.0 19.6 30.9 20.8 8.1 61.1 118.8 4.6 88.4 59.6 145.4 2.7 220.9 9.3 0.6 21.3 58.8 463.8 142.1 99.2 128.3 62.1 68.4 49.7 26.9 1.6 9.4 247.3 25.0 46.7 97.7 1.1 103.2 2.4 1.5 190.0 43.9 16.8 36.1 1.2 2.0 13.0 162.6 23.0 4.2 161.2 51.3 33.9 94.4 12.5 1.8 179.0 3.6 0.4 0.9 323.3 32.5 56.0 369.9 59.3 110.7 29.9 33.0 51.4 310.1 150.7 70.3 14.9 211.9 51.1 23.1 536.4 50.1 25.0 44.5 173.1 65.9 47.7 80.5 45.2 48.8 41.9 51.7 58.5 74.3 49.8 39.6 79.0 67.2 43.6 48.1 38.8 9.4 112.8 55.1 108.1 149.0 107.6 2.4 68.1 54.7 7.7 58.6 143.8 158.2 2.1 1.3 14.9 17.4 11.7 79.7 2.0 23.1 5.0 41.0 13.2 92.9 0.3 66.7 1.1 29.1 58.6 25.2 280.3 0.7 59.6 32.5 64.3 1.7 0.6 36.8 63.1 26.6 18.2 2.0 40.4 52.3 64.0 3.7 11.0 35.7 0.0 54.3 22.4 86.7 50.3 8.2 16.0 59.1 220.6 2.5 73.0 2.7 13.1 109.0 46.0 2.1 5.9 161.3 67.2 1.4 46.3 0.6 43.1 142.8 CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2822.0;Ionocytes: 4461.6;Urothelial cells: 2594.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "basophil: 1957.3;eosinophil: 1156.4" "Lineage enriched" "Detected in all" 32 "granulocytes: 1957.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 1521.6;RT4: 1126.8;TIME: 2266.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" 204.4 287.8 116.9 96.5 162.9 17.3 298.9 139.8 193.3 399.5 157.3 496.9 127.2 242.4 270.9 1000.2 242.3 102.4 267.5 124.3 132.3 294.2 79.4 403.0 37.4 165.8 141.0 69.0 93.4 881.8 98.1 85.4 160.2 488.5 466.2 32.6 614.5 456.4 74.4 455.3 211.2 197.0 139.2 69.5 178.2 26.4 146.5 66.1 338.0 116.6 289.4 373.1 566.4 207.1 417.6 173.7 3.5 108.7 167.7 170.8 150.1 241.1 477.8 80.8 121.9 128.5 1521.6 1.4 59.2 51.4 239.0 885.6 92.7 475.5 62.7 21.5 63.1 2.0 117.1 26.6 71.3 1.1 497.0 0.6 347.0 147.3 126.0 225.3 976.3 28.9 19.3 1.7 51.5 578.6 1.8 45.4 136.0 504.3 175.7 4.1 290.1 529.7 802.1 1126.8 0.5 34.0 240.9 195.8 215.8 789.0 91.1 42.1 2266.0 8.6 214.6 8.8 29.5 1.7 1.3 63.2 137.2 1.0 221.7 1957.3 61.1 1156.4 1.3 23.6 2.2 5.5 1.4 1.6 10.2 20.5 4.2 11.5 30.9 2.6 0.6 3.7 0.4 71.7 116.9 162.9 139.8 193.3 124.3 132.3 165.8 141.0 160.2 139.2 146.5 207.1 250.0 794.9 403.1 35.6 27.8 1037.8 1864.4 2822.0 804.1 4.9 433.5 379.5 20.9 84.4 1403.7 1075.9 0.0 21.5 8.7 929.9 137.0 599.1 3.0 457.8 66.8 496.5 172.9 10.5 0.4 178.2 271.0 356.9 60.6 722.6 653.4 42.3 522.6 43.1 618.0 0.0 0.6 744.8 4461.6 35.2 685.3 13.1 32.0 253.4 940.9 11.2 151.7 375.1 2.1 56.3 169.5 352.9 896.4 70.7 59.3 1576.4 330.0 21.7 1409.8 14.7 664.0 322.6 397.5 7.3 74.1 1214.3 1279.8 54.0 77.8 838.5 761.1 2594.9 CDC16 "ANAPC6, APC6, CUT9" ENSG00000130177 "Cell division cycle 16" Q13042 13 114234887-114272723 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042826 Approved NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA042826: AB_10793987" "unprognostic (7.32e-2)" "unprognostic (1.43e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-3)" "unprognostic (1.50e-1)" "unprognostic (7.19e-3)" "unprognostic (6.82e-3)" "unprognostic (9.86e-2)" "unprognostic (7.64e-2)" "unprognostic (4.07e-1)" "unprognostic (1.27e-2)" "unprognostic (1.08e-2)" "unprognostic (1.99e-3)" "unprognostic (2.48e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-3)" "unprognostic (1.51e-2)" 37.6 36.6 51.2 24.7 52.2 25.7 38.9 51.9 69.2 44.3 56.7 37.0 26.7 37.4 50.3 33.1 45.4 23.9 34.2 51.6 52.9 37.8 49.8 31.7 35.5 52.9 53.5 41.5 48.0 33.4 39.4 34.8 53.7 38.9 37.6 42.8 31.6 31.9 41.7 41.9 35.2 39.2 52.2 44.3 38.1 42.0 51.8 42.8 35.3 37.5 39.5 37.4 35.9 55.6 75.4 42.1 63.1 65.8 78.5 98.7 36.0 76.3 63.0 78.7 75.6 38.9 60.7 68.0 28.7 104.8 75.4 41.6 56.6 72.5 104.2 42.7 65.9 56.8 53.7 39.8 83.8 104.6 76.4 72.2 78.5 53.7 69.0 77.8 76.8 35.7 48.7 26.1 109.7 34.6 45.7 49.2 71.1 129.0 38.8 22.2 32.6 41.3 94.0 50.9 61.2 58.8 42.3 68.8 130.0 106.8 53.3 126.0 61.7 34.8 61.4 27.8 46.6 38.2 32.3 72.2 83.3 63.0 47.5 2.3 2.9 3.3 3.3 3.2 3.1 8.4 2.3 4.3 4.4 6.8 2.5 2.7 0.7 11.2 2.6 6.1 4.7 2.2 51.2 52.2 51.9 69.2 51.6 52.9 52.9 53.5 53.7 52.2 51.8 55.6 27.2 38.5 30.3 69.2 24.7 17.8 21.7 23.0 17.1 17.1 20.4 20.7 37.4 24.3 39.7 35.0 25.0 38.1 24.0 13.6 23.5 34.4 34.6 63.3 25.9 27.1 19.7 45.0 41.6 37.2 33.8 33.5 30.1 31.3 26.6 30.4 28.2 32.6 34.7 13.5 39.3 31.0 16.2 22.0 12.9 29.1 26.4 24.9 23.2 23.4 27.3 23.0 19.6 45.8 65.3 33.0 12.9 29.0 24.9 26.2 19.2 28.7 71.0 23.3 26.3 31.6 23.5 53.9 49.5 21.4 19.0 24.9 21.8 31.3 23.8 18.0 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 52.6;testis: 49.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.0;Early spermatids: 135.0;Erythroid cells: 96.0;Extravillous trophoblasts: 146.2;Spermatocytes: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.5;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.5;T-cells: 11.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.6 1.5 0.6 16.2 1.1 53.9 5.2 0.8 1.3 3.5 0.4 14.8 13.7 2.3 2.5 27.2 1.7 1.2 0.9 0.7 1.1 2.3 1.7 2.5 32.6 1.3 1.1 0.7 0.6 0.2 0.3 9.7 1.1 0.8 16.0 0.2 4.4 0.7 0.3 11.3 12.2 7.3 0.8 11.7 7.0 49.1 1.7 52.6 1.7 0.2 50.8 3.3 7.0 1.3 311.9 148.2 202.8 133.4 6.9 17.6 193.5 140.3 125.0 400.0 211.4 234.5 250.9 178.3 80.1 130.1 140.6 212.8 225.3 267.9 331.5 140.8 165.6 261.4 143.6 147.3 2.1 184.3 91.4 6.0 12.4 278.2 249.6 35.1 172.2 167.5 120.2 119.3 184.0 120.4 179.2 113.5 257.2 147.0 196.9 255.8 277.9 112.9 98.5 81.3 119.2 58.9 248.1 165.8 76.6 154.9 116.3 231.7 90.2 118.9 276.2 133.7 445.0 90.6 86.7 185.7 85.2 227.6 181.6 0.0 0.1 0.0 0.3 0.0 0.0 4.2 3.2 3.5 0.9 0.9 0.1 0.3 0.7 9.5 0.0 0.2 11.6 2.8 0.6 1.1 0.8 1.3 0.7 1.1 1.3 1.1 1.1 0.8 1.7 1.3 2.1 0.0 1.1 0.0 12.2 10.5 3.8 17.6 6.2 0.5 6.4 9.7 0.7 1.5 4.8 0.0 0.0 65.0 2.8 16.9 0.0 2.2 135.0 14.6 2.4 4.5 0.0 96.0 0.2 0.4 146.2 9.3 11.7 4.6 0.0 46.5 7.9 1.3 37.4 0.0 0.0 18.5 24.4 6.2 7.5 18.5 2.8 9.3 0.0 0.0 1.8 0.3 0.0 0.0 1.6 0.7 0.5 1.9 34.4 2.7 3.2 3.1 8.3 2.9 0.0 1.0 25.4 126.5 39.8 47.3 8.4 10.7 5.1 1.6 37.5 7.4 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;lymphoid tissue: 8.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.2;Early spermatids: 18.3;Late spermatids: 31.8;Spermatogonia: 16.3" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Golgi apparatus" "HPA005855: AB_1846364, HPA008803: " "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.7 0.9 0.8 3.3 0.8 15.3 1.1 0.7 1.0 0.6 0.7 3.5 2.0 0.6 0.9 2.4 0.2 0.3 0.4 0.8 2.0 0.7 0.8 0.3 4.4 1.1 1.9 2.2 0.7 0.8 0.8 2.6 1.7 0.6 3.9 2.0 0.8 0.6 0.4 0.6 1.8 1.1 0.8 2.0 0.9 13.3 2.0 8.8 1.8 0.3 5.6 0.9 0.9 0.7 22.2 10.7 50.0 27.2 1.7 3.2 34.2 29.9 11.3 36.7 29.6 46.8 11.2 64.9 11.4 8.0 23.4 16.3 86.6 20.6 38.6 21.4 45.1 83.8 19.0 23.1 1.7 59.4 23.4 1.7 3.1 45.8 19.6 4.6 14.1 47.8 67.6 33.6 20.1 11.8 74.8 46.6 73.4 20.2 24.2 33.2 32.9 35.1 9.5 20.7 23.5 28.8 18.6 21.6 9.5 31.7 11.3 41.9 7.2 18.0 27.7 20.3 41.4 16.7 54.2 101.5 13.5 65.2 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.0 0.8 2.0 1.1 1.9 1.7 0.8 2.0 0.7 0.3 0.0 0.0 1.0 1.1 0.4 0.4 0.8 1.8 0.5 1.2 1.0 111.2 0.0 0.1 0.0 2.1 4.2 0.2 2.4 0.0 0.4 18.3 0.5 0.9 2.7 1.2 8.0 0.2 0.9 7.4 1.5 1.5 1.3 0.0 4.6 1.4 0.3 3.1 0.0 0.5 2.0 0.0 0.6 0.9 31.8 1.5 0.5 0.0 0.0 0.1 1.1 0.0 0.5 0.0 1.1 0.8 1.9 13.0 0.7 0.4 0.4 0.2 0.4 0.0 0.1 2.2 14.5 16.3 4.3 0.0 0.3 0.6 2.4 4.1 0.5 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 7.2;NK-cells: 18.1;T-cells: 28.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Mitotic spindle" "HPA038892: AB_2676258, HPA038893: AB_2676259, HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 29.2 15.6 30.5 28.8 32.4 29.4 25.1 39.2 33.2 41.7 23.2 37.6 14.4 35.0 9.4 27.1 31.5 17.9 16.3 27.6 32.5 31.3 24.8 78.4 47.6 31.3 29.9 37.4 12.8 3.8 45.7 31.1 30.2 25.4 11.3 7.8 16.7 8.9 10.5 21.8 41.2 14.2 27.4 56.1 30.1 12.4 30.9 44.7 41.8 6.3 32.8 35.8 30.2 35.8 129.6 273.2 36.5 60.0 43.8 43.0 19.3 63.3 95.3 103.1 75.9 49.2 182.9 91.3 27.5 65.4 253.5 183.5 50.6 105.8 50.2 36.2 54.4 49.4 88.5 59.6 178.4 38.6 25.0 41.1 85.0 95.4 115.7 35.6 58.4 44.2 33.3 232.7 63.1 105.5 119.0 57.7 27.3 90.9 116.9 62.0 102.6 67.5 73.2 12.2 25.8 56.9 148.6 140.8 78.1 31.7 48.1 20.4 48.6 55.1 66.2 101.5 85.0 57.8 97.8 36.8 28.1 38.0 54.6 3.9 2.4 0.0 22.7 3.4 21.3 5.8 22.6 23.3 2.4 7.2 18.6 21.6 0.3 18.1 1.7 1.3 28.2 11.2 30.5 32.4 39.2 33.2 27.6 32.5 31.3 29.9 30.2 27.4 30.9 35.8 14.0 9.6 21.7 18.6 21.7 11.2 6.0 10.9 7.4 14.4 4.8 5.5 8.6 8.6 4.5 7.3 2.1 11.9 30.6 5.8 0.0 9.9 0.7 2.7 20.6 27.1 7.8 32.6 39.2 4.8 17.7 15.7 17.3 5.4 1.3 11.5 14.3 13.7 30.4 3.3 38.0 10.4 12.2 14.8 9.4 1.1 7.2 12.4 17.8 6.5 8.8 8.3 44.3 22.6 13.2 15.0 4.3 9.1 49.6 6.0 5.5 11.1 3.7 2.6 0.0 26.5 14.0 2.3 12.3 10.3 11.2 3.6 36.4 7.1 10.9 4.4 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 8.9;testis: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 42.1;Spermatocytes: 53.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 0.2 0.2 0.2 2.1 0.2 5.8 0.7 0.3 0.3 0.3 0.2 3.4 3.0 0.4 0.2 1.4 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.3 3.2 0.2 0.3 0.0 0.4 0.1 0.1 1.2 0.2 0.2 4.1 0.1 0.3 0.1 0.0 1.4 3.0 0.8 0.1 0.9 1.1 18.1 0.2 8.9 0.1 0.0 4.6 0.5 0.5 0.2 27.9 11.0 38.4 28.9 0.9 3.6 9.9 16.4 17.5 36.2 50.3 27.3 52.8 13.3 13.8 10.1 40.5 14.9 31.7 25.9 34.9 11.1 21.5 9.6 15.0 21.2 0.3 6.3 10.0 0.8 0.9 22.0 18.0 3.8 24.6 28.9 14.8 24.2 22.9 15.5 19.3 16.7 9.7 22.3 12.2 11.9 34.2 15.0 6.4 8.4 19.2 11.9 36.8 11.0 16.9 32.6 18.7 13.9 7.2 19.9 16.8 13.9 26.5 15.0 13.4 13.0 8.3 14.3 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.0 0.0 1.3 0.9 0.6 0.3 1.1 1.8 0.0 0.9 0.8 0.3 0.0 0.2 0.0 0.0 5.0 0.5 1.8 0.0 0.1 41.4 0.4 0.9 0.6 0.0 9.5 1.3 0.0 6.9 1.1 3.6 1.2 0.0 5.5 1.4 0.4 2.7 0.0 1.0 3.9 2.0 0.6 0.5 42.1 1.8 1.2 0.0 1.0 0.6 0.0 0.0 1.0 0.3 0.0 1.4 0.4 4.5 0.3 0.9 0.1 0.1 0.0 0.0 0.2 0.9 53.6 13.0 4.3 0.4 1.4 0.6 0.2 4.9 0.6 CDC27 "ANAPC3, APC3, D0S1430E, D17S978E, NUC2" ENSG00000004897 "Cell division cycle 27" P30260 17 47117703-47189422 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 149.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016315, HPA028129, HPA052399, HPA065835" Supported Enhanced Nucleoplasm NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB016315: AB_627228, HPA028129: AB_10603559, HPA052399: AB_2681814, HPA065835: " "unprognostic (2.34e-2)" "unprognostic (8.83e-3)" "prognostic favorable (1.77e-4)" "unprognostic (4.26e-2)" "unprognostic (7.99e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.38e-4)" "prognostic unfavorable (8.15e-4)" "unprognostic (1.98e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-3)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.39e-5)" "unprognostic (2.64e-1)" "unprognostic (1.58e-1)" "unprognostic (7.95e-2)" "unprognostic (3.66e-2)" 23.0 15.2 9.3 20.1 12.0 27.6 18.1 18.3 15.2 18.0 5.6 15.2 14.6 20.7 13.1 16.6 15.1 18.4 23.3 11.6 12.0 15.2 22.4 18.1 23.4 10.6 10.8 17.0 14.5 24.4 10.6 25.5 11.5 15.1 17.7 13.7 12.2 15.4 22.4 12.1 13.8 24.5 10.5 19.1 15.9 25.0 11.3 25.0 42.4 28.8 24.0 19.8 11.2 11.3 80.7 84.1 69.1 56.1 45.5 72.0 41.0 110.9 99.0 103.3 105.1 54.2 41.4 107.4 72.7 93.5 66.0 37.5 75.2 62.6 141.2 155.5 77.2 125.0 92.9 48.6 49.2 74.4 54.6 52.4 30.2 93.5 73.1 49.7 108.6 61.6 101.6 58.0 85.2 68.3 91.8 33.5 32.8 45.2 67.8 48.9 177.3 47.8 62.0 50.0 45.8 55.9 55.4 19.4 61.2 58.6 58.6 51.7 116.9 107.1 91.9 68.6 82.9 58.8 110.2 95.8 59.4 43.6 76.0 9.3 3.2 4.9 5.3 7.1 5.2 4.0 4.2 5.5 4.2 6.3 4.2 5.0 4.0 8.7 5.3 5.2 8.3 3.5 9.3 12.0 18.3 15.2 11.6 12.0 10.6 10.8 11.5 10.5 11.3 11.3 63.7 9.6 26.3 61.0 28.7 26.0 17.8 25.9 38.1 22.1 21.3 17.5 39.8 21.5 27.1 20.2 16.7 31.4 22.5 11.5 15.6 28.1 28.9 20.8 33.9 50.7 13.8 149.8 124.5 26.5 35.6 41.4 21.4 22.1 26.6 24.8 38.9 27.1 27.2 35.3 104.4 12.8 8.2 28.5 22.1 33.6 28.3 30.6 7.2 83.4 31.5 19.4 35.0 89.0 96.1 30.1 9.5 29.7 39.0 18.7 13.5 23.6 16.2 14.9 19.7 41.6 40.8 97.3 38.6 32.6 26.9 11.5 27.8 34.2 16.2 17.1 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 35.1 36.7 52.0 13.3 51.2 34.5 34.2 51.5 63.0 36.9 47.5 62.5 17.8 33.5 14.1 40.5 33.6 10.1 80.0 52.7 48.7 32.1 88.0 32.1 12.5 51.0 50.7 35.6 58.5 18.7 43.4 29.2 50.8 36.9 11.5 28.2 34.2 19.3 105.0 51.8 27.6 18.5 48.2 31.0 38.6 100.2 52.7 16.4 26.7 63.2 9.7 43.7 34.2 52.7 54.8 54.6 66.4 54.7 29.2 28.4 68.5 47.8 36.1 50.2 51.9 86.1 32.8 29.5 49.3 34.1 30.1 36.9 52.1 40.2 25.0 49.2 146.0 27.8 35.5 94.5 73.6 39.0 32.4 36.4 58.9 42.2 43.6 38.8 60.6 41.2 120.3 57.5 33.8 80.7 53.3 53.6 85.3 39.4 51.7 49.1 35.1 51.2 38.0 32.4 87.2 65.9 41.5 42.1 85.2 53.2 34.0 57.4 50.5 36.5 43.7 86.2 65.2 57.7 47.3 40.1 50.0 55.6 38.8 3.2 2.5 4.7 1.6 2.7 1.1 2.3 2.1 2.9 2.0 1.0 1.6 1.6 8.2 1.2 3.5 1.6 2.5 1.0 52.0 51.2 51.5 63.0 52.7 48.7 51.0 50.7 50.8 48.2 52.7 52.7 39.4 0.0 5.4 21.9 11.4 46.8 17.5 5.4 16.5 35.5 43.4 47.1 27.7 27.1 3.5 14.7 25.0 44.3 30.9 47.4 13.7 24.9 63.9 29.6 28.3 27.7 13.2 77.7 8.3 20.5 55.4 21.4 16.8 42.3 0.0 28.1 15.7 41.1 27.9 16.8 6.3 34.0 14.2 14.5 38.6 249.4 18.0 20.6 19.6 2.8 15.1 68.9 20.6 6.6 12.9 45.0 27.0 15.1 25.0 34.8 25.9 18.9 5.5 44.3 13.1 22.6 34.9 22.4 54.6 15.2 54.7 63.1 22.0 27.1 23.7 27.9 CDC37 P50CDC37 ENSG00000105401 "Cell division cycle 37, HSP90 cochaperone" Q16543 19 10391133-10420121 "Cancer-related genes, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003928, CAB004214" Supported Supported Cytosol NA NA 610000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB004214: AB_627232, HPA003928: AB_1846373" "unprognostic (2.40e-1)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (2.33e-2)" "unprognostic (2.46e-3)" "unprognostic (6.21e-2)" "unprognostic (1.37e-1)" "unprognostic (7.90e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-3)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "prognostic favorable (2.33e-4)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (3.02e-2)" 149.9 93.6 82.2 81.3 84.6 89.5 130.6 75.0 104.2 111.4 72.1 109.9 58.1 110.0 34.2 125.7 98.5 39.8 186.0 86.3 85.8 123.2 102.2 129.9 66.5 85.9 85.8 105.9 100.3 59.3 74.6 62.7 88.1 105.0 48.2 34.6 96.6 52.2 313.2 100.9 96.3 50.2 75.7 137.5 102.8 77.5 82.5 69.3 100.8 222.6 52.4 110.3 103.0 87.8 279.2 181.2 95.5 137.5 128.8 111.8 122.9 322.8 144.6 198.3 168.8 209.1 106.7 165.3 254.7 198.3 117.2 169.9 130.6 208.7 136.4 133.6 387.2 313.9 147.2 300.9 202.5 183.9 137.9 136.9 112.5 231.8 104.0 113.5 258.1 142.2 248.2 193.8 156.1 265.3 184.3 450.2 234.6 175.5 317.8 181.0 128.3 190.3 185.1 178.2 111.5 161.9 151.5 158.1 143.1 72.7 108.4 195.7 290.0 230.8 133.9 319.9 262.2 261.3 276.5 204.4 181.4 294.1 191.2 77.2 110.8 97.1 114.4 107.9 103.1 73.2 91.8 103.5 105.2 62.9 70.0 81.8 60.2 101.1 112.6 89.4 106.8 145.6 82.2 84.6 75.0 104.2 86.3 85.8 85.9 85.8 88.1 75.7 82.5 87.8 420.1 54.5 95.5 51.6 163.7 148.6 119.3 149.0 127.5 78.0 85.0 75.8 71.3 75.8 114.8 64.4 39.6 188.9 166.1 192.3 101.8 199.8 119.0 88.2 120.5 267.5 81.3 89.8 35.0 199.0 430.2 108.3 226.8 126.4 134.3 90.8 172.1 45.3 210.2 89.2 24.6 181.3 105.8 83.9 313.8 253.8 106.2 165.6 138.7 29.0 165.1 75.8 135.9 21.1 32.5 297.6 183.5 103.4 170.5 120.1 117.9 89.7 78.2 84.4 78.9 94.4 138.6 72.4 73.5 138.1 133.7 242.4 164.2 123.0 186.1 156.1 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDC73 "C1orf28, FIHP, HRPT1, HRPT2, parafibromin" ENSG00000134371 "Cell division cycle 73" Q6P1J9 1 193121983-193254815 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002326, CAB016359, HPA069324" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB016359: AB_628102, HPA002326: , HPA069324: " "unprognostic (4.41e-2)" "unprognostic (6.22e-2)" "unprognostic (1.90e-2)" "unprognostic (5.30e-2)" "unprognostic (2.88e-3)" "unprognostic (3.53e-2)" "unprognostic (2.48e-3)" "unprognostic (5.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.40e-1)" "unprognostic (7.23e-3)" "unprognostic (2.17e-1)" "unprognostic (5.44e-3)" "unprognostic (3.47e-1)" "unprognostic (2.49e-1)" "unprognostic (6.73e-3)" "unprognostic (2.98e-3)" 11.3 9.5 5.8 7.3 6.9 8.9 10.7 6.1 7.3 11.1 4.5 10.2 5.6 10.3 8.5 8.4 7.2 5.9 9.6 4.6 8.1 10.4 9.2 7.9 7.5 6.9 7.2 11.5 6.4 12.9 5.6 9.4 7.9 15.1 9.0 10.1 7.7 9.7 12.2 7.0 7.7 10.3 7.9 8.6 7.0 5.9 6.5 10.6 13.1 5.6 7.9 9.7 8.5 8.3 9.3 2.4 16.6 11.5 18.3 18.9 4.9 6.7 16.1 19.5 16.4 6.5 12.3 10.5 5.2 20.4 8.8 10.7 16.8 14.9 24.7 6.1 4.1 7.3 8.1 7.2 16.1 16.0 11.6 13.7 16.0 14.9 17.7 20.6 17.8 11.1 8.1 14.2 28.8 3.5 13.9 9.2 11.9 21.9 2.5 10.6 7.0 15.0 26.6 8.2 3.9 12.3 8.6 26.8 22.3 21.0 18.3 14.0 9.2 19.3 2.2 16.4 12.6 12.2 7.2 7.6 11.9 10.2 30.1 2.2 0.5 0.7 0.8 1.0 1.2 0.9 1.1 0.6 0.6 0.5 1.4 1.2 0.3 1.3 0.8 1.0 0.9 0.4 5.8 6.9 6.1 7.3 4.6 8.1 6.9 7.2 7.9 7.9 6.5 8.3 44.5 35.3 25.4 54.5 44.9 37.2 35.6 38.4 36.5 30.4 24.4 21.8 44.5 25.8 27.2 33.1 35.5 25.0 48.0 18.2 33.2 37.5 19.7 24.6 39.6 38.0 11.4 40.8 71.9 32.2 42.0 39.1 28.1 30.8 41.1 17.6 25.4 17.2 31.6 21.9 76.4 15.8 34.6 27.4 49.1 8.5 33.5 38.3 28.4 54.4 46.0 35.2 41.2 78.4 112.3 35.5 16.9 36.1 50.3 34.9 19.2 36.3 20.6 36.7 26.3 49.0 48.3 55.6 33.0 36.8 34.9 38.0 44.4 30.3 18.6 27.9 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Endometrial stromal cells: 125.0;Excitatory neurons: 122.2;Fibroblasts: 102.2;Microglial cells: 145.2;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 106.3;Theca cells: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 246.5;BJ hTERT+: 139.3;fHDF/TERT166: 332.3;HSkMC: 217.4;PC-3: 291.2;U-2197: 194.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" 15.1 8.6 12.4 25.7 27.9 0.3 10.7 10.8 15.8 57.7 13.8 11.4 7.0 52.8 9.5 7.4 12.5 58.6 10.2 19.2 21.4 10.2 1.8 45.6 17.5 17.1 24.1 178.2 3.4 2.6 10.4 122.2 17.3 20.0 12.2 14.0 12.7 24.3 2.6 10.9 8.9 54.3 21.1 89.3 11.8 8.0 19.3 3.7 8.1 3.1 13.0 47.6 13.6 21.4 0.2 0.0 51.4 0.1 35.7 77.5 0.3 246.5 139.3 61.0 34.5 4.6 0.2 0.0 0.0 332.3 0.0 0.1 0.1 1.7 43.4 0.0 2.1 0.0 1.4 0.0 29.7 0.0 14.4 217.4 0.1 74.7 14.9 0.0 17.4 0.0 0.0 0.0 33.1 0.3 0.1 0.3 19.2 37.4 291.2 0.8 38.0 0.0 0.0 0.0 0.8 36.0 0.1 0.3 0.2 64.5 0.3 0.1 0.0 124.4 17.2 194.0 70.1 0.0 0.0 0.1 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 27.9 10.8 15.8 19.2 21.4 17.1 24.1 17.3 21.1 19.3 21.4 11.4 3.2 0.0 93.0 0.1 3.8 1.0 7.9 0.0 19.9 1.0 7.4 3.1 1.5 3.3 0.0 0.0 2.6 0.2 0.1 0.0 0.1 2.7 3.9 125.0 17.8 0.0 2.7 122.2 0.0 2.3 102.2 0.5 2.7 0.0 60.0 68.9 0.0 4.7 0.0 67.6 0.6 0.0 0.6 6.9 4.2 52.5 0.9 5.4 145.2 0.0 41.9 0.0 158.3 106.3 0.8 0.0 77.5 0.0 1.6 0.0 1.4 0.4 2.1 26.3 12.8 38.0 1.7 1.1 0.5 3.1 5.6 1.1 160.2 0.3 0.5 CDH17 "cadherin, HPT-1" ENSG00000079112 "Cadherin 17" Q12864 8 94127162-94217303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "intestine: 314.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 569.4;Enteroendocrine cells: 108.4;Intestinal goblet cells: 183.7;Paneth cells: 408.6;Proximal enterocytes: 336.9;Undifferentiated cells: 241.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 156.4;stomach cancer: 54.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 16.0" "Lineage enriched" "Detected in single" 17 "granulocytes: 16.0" "Cell line enhanced" "Detected in some" "CACO-2: 98.8;OE19: 430.1;U-266/70: 157.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023614, HPA023616, CAB025143, HPA026556" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA 7500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB025143: , HPA023614: AB_1845896, HPA023616: AB_1845895, HPA026556: AB_1845897" "unprognostic (2.08e-1)" "unprognostic (5.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (3.06e-2)" "unprognostic (5.60e-2)" "unprognostic (3.38e-3)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.47e-2)" "unprognostic (3.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (7.33e-2)" "unprognostic (1.46e-2)" 0.9 0.2 0.7 28.8 0.5 2.7 0.5 1.1 0.8 0.1 1.9 260.9 314.2 1.3 0.8 1.7 0.3 3.0 0.6 0.5 0.2 0.8 0.3 0.2 1.5 0.3 0.1 0.5 1.7 0.0 0.0 0.2 0.3 1.2 246.7 0.5 0.9 1.6 0.5 0.6 270.6 9.3 0.1 5.5 2.5 0.6 0.2 0.3 0.7 0.1 1.8 0.8 0.1 0.7 0.2 18.5 0.2 0.4 0.0 0.4 1.6 0.2 0.3 0.2 0.3 98.8 3.5 0.3 0.3 0.0 0.1 1.0 0.3 0.3 0.3 0.2 1.1 0.1 0.8 0.6 0.3 0.2 4.3 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.4 1.5 0.1 0.7 0.5 1.3 0.3 430.1 0.5 0.3 0.0 2.8 0.3 0.2 1.3 1.2 0.4 0.4 0.5 0.4 0.7 0.9 0.0 0.6 0.7 1.2 0.5 157.2 0.3 0.2 0.3 0.3 0.6 2.9 0.9 1.4 0.2 0.8 0.1 0.3 0.2 0.1 0.5 0.8 0.2 0.3 16.0 0.7 0.5 0.4 0.2 0.2 0.7 0.5 1.1 0.8 0.5 0.2 0.3 0.1 0.3 0.1 0.2 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 569.4 0.0 0.3 1.0 0.0 0.0 0.0 108.4 0.0 0.5 0.0 0.0 0.1 2.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 183.7 0.0 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 408.6 0.0 0.2 0.0 336.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 2.1 0.0 241.6 0.1 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.2;lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.9;Erythroid cells: 209.6;Extravillous trophoblasts: 144.6;Spermatocytes: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.2;T-reg: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003387, CAB003799, CAB079974" Enhanced Supported Nucleoplasm,Cytosol NA Yes 51000 "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB003799: AB_344898, CAB079974: , HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favorable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (1.10e-6)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 3.8 1.8 0.9 17.0 1.0 53.2 7.4 0.9 1.5 5.2 0.9 17.6 16.3 7.1 12.2 17.5 3.7 4.3 1.4 0.9 1.0 3.1 3.2 4.7 40.6 1.2 1.2 2.3 0.8 2.5 4.1 19.4 1.1 1.7 20.8 1.3 3.2 5.2 1.4 13.2 14.5 8.0 0.9 9.0 10.1 25.1 1.4 74.0 3.6 2.2 47.5 7.1 6.9 1.0 249.9 93.5 241.1 96.0 15.4 23.6 99.0 183.8 132.7 218.8 209.0 218.9 213.7 226.2 69.6 50.6 79.6 149.9 166.2 106.8 225.8 162.3 121.1 119.4 84.4 128.1 2.8 184.5 117.6 4.7 10.4 142.1 137.0 49.6 133.3 146.2 185.1 270.3 246.9 66.3 234.0 131.1 106.6 149.3 193.1 199.7 224.5 111.3 84.3 81.4 112.7 98.7 123.5 184.9 96.3 130.0 199.9 111.5 55.4 92.8 197.9 99.1 255.8 104.9 180.8 205.6 79.9 203.5 117.6 0.0 0.0 0.0 0.3 0.1 0.2 0.5 0.7 1.3 0.3 0.4 0.2 0.7 0.0 3.2 0.1 0.9 3.4 0.9 0.9 1.0 0.9 1.5 0.9 1.0 1.2 1.2 1.1 0.9 1.4 1.0 7.7 0.0 3.2 0.3 7.1 39.8 5.4 29.9 2.8 1.1 5.3 6.1 0.8 0.0 10.2 18.4 0.0 80.9 3.6 8.9 3.9 0.8 18.7 10.8 6.2 10.5 3.0 209.6 0.4 0.0 144.6 13.3 13.3 9.4 0.0 51.5 7.5 1.3 57.2 0.0 0.2 14.6 30.5 20.5 18.1 10.4 2.1 16.5 1.8 1.9 1.0 1.0 3.1 0.0 0.1 0.4 0.7 0.7 32.1 4.3 2.2 3.0 17.6 0.7 0.0 0.5 24.6 110.0 39.6 33.8 18.6 22.0 10.3 2.1 26.6 10.4 CDK12 "CRK7, CRKR, CRKRS, KIAA0904" ENSG00000167258 "Cyclin dependent kinase 12" Q9NYV4 17 39461486-39564907 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 307.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008038, HPA073305" Supported Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA008038: AB_1078570, HPA073305: " "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (7.56e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.56e-3)" "unprognostic (2.37e-2)" "unprognostic (3.86e-2)" "unprognostic (3.00e-3)" "unprognostic (6.87e-3)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "unprognostic (9.10e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-2)" "unprognostic (5.32e-1)" 9.5 7.6 2.5 14.0 1.9 34.3 9.5 8.0 4.0 11.0 4.1 9.8 9.9 10.8 6.0 10.4 9.2 9.2 6.8 1.6 2.9 8.0 12.3 9.2 15.1 3.0 1.7 11.9 8.7 13.0 6.2 11.5 1.6 9.8 10.4 11.7 9.2 9.3 6.7 10.6 10.4 10.0 0.3 12.9 10.3 17.7 3.4 17.9 12.2 7.8 15.3 13.1 9.1 3.3 31.9 40.0 24.9 22.2 17.2 19.0 21.1 28.9 24.7 39.9 29.0 48.1 19.8 45.4 24.6 31.1 38.7 51.8 49.2 36.6 38.4 29.6 38.7 49.7 26.9 36.3 16.4 66.9 33.4 20.4 25.0 48.2 37.6 16.0 24.4 27.7 85.2 30.7 22.9 14.3 57.9 17.7 23.8 16.0 16.9 36.8 50.3 25.7 14.8 38.8 24.6 15.7 37.0 307.8 25.1 34.8 38.5 29.3 26.4 34.5 27.6 24.5 37.9 23.6 18.4 63.5 24.2 28.2 23.0 11.2 2.0 3.2 2.6 1.5 1.8 1.8 1.5 1.7 1.2 3.1 1.7 1.6 7.0 4.5 1.3 2.7 1.2 0.7 2.5 1.9 8.0 4.0 1.6 2.9 3.0 1.7 1.6 0.3 3.4 3.3 41.4 25.6 29.1 50.9 59.0 64.6 58.5 31.2 50.1 46.6 38.1 26.9 14.5 32.9 40.3 38.6 64.6 33.2 59.0 44.6 13.7 30.2 25.1 49.8 63.4 40.6 31.1 39.3 53.9 27.5 29.9 39.2 45.3 63.1 29.1 43.8 32.2 46.3 27.4 35.3 52.9 39.6 42.7 45.9 49.1 17.3 37.3 41.3 26.6 32.8 41.4 27.8 48.4 47.3 53.1 47.9 33.9 33.8 53.5 81.5 33.3 16.7 38.1 65.4 32.9 48.0 48.5 140.2 104.8 53.0 69.0 58.3 59.0 46.0 39.9 84.8 CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966781-55972789 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Extravillous trophoblasts: 84.7;Melanocytes: 87.2;Syncytiotrophoblasts: 170.7" "Cancer enhanced" "Detected in all" "melanoma: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 540.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013115, HPA066915" Enhanced Enhanced Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Centrosome, Cytosol" "CAB013115: AB_2536375, HPA066915: AB_2685748" "unprognostic (2.36e-2)" "unprognostic (2.60e-1)" "unprognostic (3.71e-2)" "unprognostic (1.83e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.94e-4)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (5.38e-3)" "unprognostic (4.69e-3)" "prognostic unfavorable (1.46e-10)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (6.75e-2)" 15.3 9.2 3.5 16.3 3.4 36.0 14.2 3.6 4.9 13.4 6.4 12.5 9.8 13.7 6.3 14.9 13.7 10.8 10.9 3.5 3.8 14.7 16.2 22.9 21.6 4.7 4.0 16.3 10.0 7.9 4.9 47.3 4.1 12.6 14.9 6.5 10.9 14.3 7.0 22.7 12.3 19.5 4.2 14.5 12.2 6.6 4.1 37.2 9.6 8.1 24.8 18.1 12.9 3.9 81.7 39.1 93.6 52.4 19.2 24.9 172.2 98.9 53.5 123.3 114.8 89.4 76.3 77.5 70.9 37.9 46.4 50.8 73.4 44.9 126.8 86.9 68.0 89.0 65.0 34.6 6.3 70.4 61.4 12.6 10.9 83.8 29.1 36.1 63.1 76.8 85.6 68.0 88.3 60.8 149.9 61.7 36.9 55.8 60.7 143.7 86.2 57.1 36.5 77.1 37.4 48.1 114.1 41.7 540.3 54.9 88.9 51.1 34.5 82.9 76.3 65.0 71.0 37.4 46.3 95.5 47.4 51.1 74.2 3.6 2.6 2.2 4.7 2.7 4.6 6.5 2.1 3.5 1.9 3.7 2.0 3.7 1.2 3.4 1.2 7.9 5.4 3.3 3.5 3.4 3.6 4.9 3.5 3.8 4.7 4.0 4.1 4.2 4.1 3.9 17.9 16.0 4.8 1.3 7.3 28.0 23.9 6.2 12.5 0.0 14.5 8.9 3.1 11.5 7.6 1.8 0.0 92.8 7.1 3.7 1.9 11.5 0.6 7.4 6.5 18.2 5.4 14.7 0.1 5.7 84.7 15.7 9.2 13.0 10.8 12.0 10.4 9.1 13.3 1.7 0.1 7.2 6.1 4.7 43.8 0.8 14.9 4.9 87.2 1.9 28.4 4.2 5.2 0.0 0.5 12.3 1.5 4.5 11.8 13.4 2.8 4.5 4.4 3.6 0.0 10.1 11.6 3.1 7.4 14.5 31.4 170.7 9.6 4.8 9.7 19.3 CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "glioma: 175.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 10 "HBEC3-KT: 2594.8;LHCN-M2: 2819.4;RH-30: 8902.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear membrane, Nucleoli" "CAB013116: AB_2536376, CAB069405: AB_1613464, HPA006024: AB_2667497" "unprognostic (8.88e-2)" "unprognostic (2.53e-1)" "unprognostic (5.27e-2)" "unprognostic (9.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.09e-7)" "unprognostic (7.39e-2)" "unprognostic (3.23e-3)" "unprognostic (2.93e-2)" "unprognostic (3.19e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.15e-5)" "unprognostic (3.32e-1)" "unprognostic (1.67e-1)" "unprognostic (3.64e-1)" "unprognostic (1.57e-2)" 69.7 87.8 35.0 52.8 37.9 72.0 76.6 37.7 36.9 84.3 35.9 62.6 40.2 97.4 64.2 57.2 69.4 57.1 58.9 33.6 37.1 58.5 51.5 58.0 66.8 37.1 36.9 97.3 70.9 63.5 67.7 52.4 36.8 52.7 63.3 14.5 54.4 54.1 48.2 58.9 47.2 80.4 37.3 51.5 54.8 24.1 37.3 67.6 66.0 52.7 70.6 71.6 60.7 37.6 207.1 235.7 295.7 268.0 253.7 220.7 210.4 116.1 347.9 468.5 385.7 338.2 189.1 297.4 200.2 173.6 293.2 158.0 396.3 2594.8 354.9 150.9 209.0 275.4 149.5 237.9 297.0 309.7 182.5 221.5 180.9 294.2 326.7 326.4 304.8 280.0 301.3 242.7 2819.4 304.9 296.7 256.5 347.0 208.0 249.8 267.3 8902.5 272.1 147.2 320.6 271.2 251.7 205.3 150.2 310.0 195.1 202.8 380.7 146.1 233.6 217.0 265.8 233.1 122.2 206.1 450.8 214.1 291.3 286.9 9.5 46.5 10.3 79.6 65.6 81.8 93.5 70.0 72.5 66.7 90.0 93.0 84.4 4.4 56.6 41.9 84.9 57.0 73.6 35.0 37.9 37.7 36.9 33.6 37.1 37.1 36.9 36.8 37.3 37.3 37.6 47.1 22.4 30.8 7.8 40.0 89.7 78.6 83.4 74.0 15.9 67.2 82.2 0.7 51.5 35.3 47.8 10.4 82.9 26.1 15.9 70.5 93.1 13.5 14.9 77.7 50.8 45.6 98.0 5.2 62.5 134.5 79.4 28.5 22.6 69.1 60.2 39.7 35.8 132.9 18.5 6.7 42.2 40.7 25.1 44.1 8.0 64.0 31.2 53.4 6.5 41.9 51.4 29.9 5.5 8.0 48.3 18.9 63.2 57.8 113.9 14.0 80.9 7.4 17.9 32.9 62.1 61.9 32.1 48.3 74.5 86.1 46.8 32.3 78.8 78.7 49.4 CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836573 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.1" "Cell type enhanced" "Detected in many" "Early spermatids: 215.9;Erythroid cells: 213.5;Late spermatids: 237.0;Oligodendrocytes: 235.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 378.4;REH: 173.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA 26000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB004363: AB_627242, HPA002637: AB_1846432" "unprognostic (1.29e-1)" "unprognostic (5.98e-3)" "unprognostic (9.07e-2)" "unprognostic (2.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.24e-2)" "unprognostic (3.39e-1)" "unprognostic (2.42e-3)" "unprognostic (7.19e-2)" "unprognostic (7.78e-3)" "prognostic unfavorable (3.86e-6)" "unprognostic (4.06e-2)" "unprognostic (4.09e-3)" "unprognostic (1.09e-1)" "unprognostic (7.88e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (2.33e-5)" 3.7 7.3 6.7 4.7 7.1 18.1 4.9 5.4 5.1 4.8 2.6 5.9 6.1 3.1 2.1 4.2 2.9 3.6 4.7 4.0 5.0 4.4 5.9 4.1 6.6 6.3 6.7 2.7 6.2 9.9 1.7 17.3 6.3 3.0 7.5 0.5 5.7 4.2 1.0 6.8 7.2 3.2 5.8 4.9 9.1 3.3 9.6 41.1 2.4 2.3 6.2 3.8 4.6 8.8 27.1 11.3 34.9 23.9 10.6 11.5 5.8 27.2 18.4 14.3 13.5 34.7 20.9 21.7 14.4 19.9 8.4 15.8 20.8 42.6 34.4 43.0 10.6 50.8 23.3 34.7 6.3 33.0 2.7 11.5 23.1 17.9 90.8 13.4 5.6 75.1 49.3 55.5 26.7 5.9 378.4 3.8 9.8 37.4 9.1 173.7 112.0 36.4 20.3 0.7 18.1 113.8 3.7 9.8 17.1 26.0 0.6 54.9 19.3 44.1 63.7 18.0 54.2 27.4 0.5 27.6 6.9 112.1 60.8 0.9 0.2 0.6 0.6 0.4 0.9 0.2 0.6 0.8 0.5 0.3 0.7 0.7 0.1 0.7 0.4 0.9 0.3 0.3 6.7 7.1 5.4 5.1 4.0 5.0 6.3 6.7 6.3 5.8 9.6 8.8 38.6 25.6 3.7 2.9 17.7 60.3 23.5 55.0 62.6 0.4 20.7 21.2 18.1 22.8 32.8 22.0 0.0 53.8 30.5 12.1 9.8 37.0 215.9 3.1 29.0 30.7 16.8 213.5 114.7 23.3 5.3 28.5 42.3 6.9 25.3 39.2 11.4 27.0 16.0 0.0 60.3 63.7 28.5 23.0 48.6 237.0 5.0 27.6 19.6 108.7 22.4 0.8 39.1 119.6 235.3 94.7 22.8 3.4 85.3 47.1 20.1 8.2 11.9 0.0 6.6 100.8 32.2 2.7 33.6 36.7 50.4 17.6 42.5 62.8 92.7 27.3 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 121.0;Extravillous trophoblasts: 343.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 169.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932, HPA008453, CAB079975" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Plasma membrane, Cytosol" "CAB004364: AB_627243, CAB079975: , HPA007932: AB_1078492, HPA008453: " "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavorable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 13.4 19.8 9.4 9.5 10.2 29.1 14.8 10.9 12.9 17.5 11.5 13.7 13.3 12.1 12.9 37.3 12.5 6.4 12.4 9.5 10.5 18.4 13.6 12.7 4.8 9.7 9.7 11.7 14.1 3.2 18.2 16.2 9.8 13.7 7.4 12.8 18.9 4.8 26.8 25.3 12.2 7.7 9.8 12.6 13.5 30.6 10.0 9.3 13.2 15.0 13.3 16.1 19.9 9.4 42.8 5.9 19.4 30.6 6.4 24.4 169.5 30.9 37.5 46.2 42.9 62.2 64.5 3.7 36.4 36.8 34.2 65.3 10.8 31.3 40.6 9.0 3.1 8.6 21.4 25.9 32.8 17.9 33.8 7.1 61.3 1.8 46.0 24.5 32.5 22.3 16.3 16.1 13.3 33.3 9.4 51.7 20.7 2.8 25.4 12.3 0.7 27.1 42.6 25.4 8.6 17.5 11.6 50.4 42.4 28.1 44.9 39.3 7.4 17.1 27.4 33.1 18.2 14.4 30.4 16.5 31.4 10.2 15.5 27.9 7.9 16.2 5.3 8.9 7.9 10.6 7.8 10.6 7.3 14.5 5.9 6.4 8.2 8.6 4.7 8.9 10.5 6.1 9.4 10.2 10.9 12.9 9.5 10.5 9.7 9.7 9.8 9.8 10.0 9.4 12.2 16.0 13.2 10.7 7.8 57.7 21.4 32.9 15.4 6.4 12.3 14.7 11.3 10.0 20.2 5.5 12.5 121.0 11.7 10.2 15.6 27.8 26.8 33.1 10.7 11.6 3.0 9.9 17.6 21.6 343.6 13.0 9.7 27.2 15.8 7.4 7.1 6.7 24.0 1.7 13.7 12.3 20.3 8.5 6.0 7.9 7.5 8.5 7.2 11.2 11.6 10.4 15.5 8.0 11.9 29.3 16.2 7.2 5.8 28.2 12.3 29.3 42.4 8.7 26.3 10.0 12.5 70.1 18.6 15.9 41.9 64.6 11.4 6.8 13.2 29.8 CDKN1A "CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1" ENSG00000124762 "Cyclin dependent kinase inhibitor 1A" P38936 6 36676460-36687337 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 74.5" "Group enriched" "Detected in many" 9 "B-cells: 20.7;dendritic cells: 21.5;monocytes: 74.5" "Cell line enhanced" "Detected in many" "HHSteC: 798.5;HSkMC: 586.5;hTCEpi: 775.8;LHCN-M2: 604.2" "Region enhanced" "Detected in all" "olfactory bulb: 76.0" "Low region specificity" "Detected in all" "CAB000064, HPA005946, CAB069401" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies" "CAB000064: , CAB069401: AB_1620493, HPA005946: AB_2667477" "unprognostic (7.99e-3)" "unprognostic (4.01e-2)" "unprognostic (1.58e-1)" "prognostic favorable (3.14e-5)" "unprognostic (1.57e-2)" "unprognostic (2.19e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.30e-1)" "unprognostic (7.27e-2)" "unprognostic (2.79e-2)" "unprognostic (7.55e-3)" "prognostic favorable (4.95e-5)" "unprognostic (8.32e-2)" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (3.21e-2)" 322.1 98.1 47.0 62.1 48.1 72.7 144.2 47.3 60.9 123.3 85.9 119.0 115.2 74.4 41.0 203.2 213.9 132.6 170.6 47.2 49.5 149.9 173.4 182.2 17.3 63.7 54.6 184.9 130.5 70.1 104.4 44.7 53.4 91.4 108.2 29.2 79.1 29.4 241.6 224.4 130.0 114.3 55.0 34.4 121.3 47.0 50.3 59.7 77.5 26.9 21.8 212.7 142.3 53.6 27.0 108.1 80.1 2.0 273.3 490.3 149.5 435.6 344.8 52.3 203.7 9.6 25.3 18.3 15.5 267.9 48.0 60.2 3.7 477.7 82.4 36.2 22.0 3.0 85.8 137.0 798.5 0.5 127.7 586.5 775.8 476.2 147.1 309.3 275.3 1.4 5.1 120.8 604.2 57.4 3.9 11.3 10.2 112.8 15.5 54.4 67.1 31.9 91.2 201.5 36.7 35.6 101.3 8.4 21.3 185.2 32.7 111.2 155.8 91.5 86.9 6.2 36.4 202.0 42.9 54.5 118.7 9.9 261.0 0.0 22.8 0.5 0.5 52.2 0.8 20.7 1.1 0.6 20.0 16.2 0.3 0.4 4.2 0.7 74.5 21.5 2.9 34.2 47.0 48.1 47.3 60.9 47.2 49.5 63.7 54.6 53.4 55.0 50.3 53.6 571.2 83.3 45.1 1.0 126.9 440.5 340.1 293.1 512.8 0.8 203.9 187.6 151.6 41.5 214.4 68.0 0.0 42.1 56.4 505.3 46.9 217.6 0.9 227.9 57.3 327.1 175.5 5.7 0.5 264.7 52.8 302.4 150.9 199.2 104.4 20.4 71.7 68.9 72.9 0.0 0.4 197.1 156.6 62.0 556.0 3.9 34.5 277.6 218.7 5.6 280.6 58.4 2.1 0.0 0.5 429.9 466.1 16.6 376.4 201.7 383.2 17.2 215.1 3.1 26.3 303.6 471.6 1.2 1.7 620.9 672.0 155.3 106.0 10.7 75.8 478.0 CDKN1B "KIP1, P27KIP1" ENSG00000111276 "Cyclin dependent kinase inhibitor 1B" P46527 12 12715058-12722369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003691, CAB021888, HPA059086" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB003691: AB_425362, CAB021888: , HPA059086: AB_2683900" "unprognostic (5.67e-2)" "unprognostic (9.76e-2)" "prognostic favorable (5.15e-4)" "unprognostic (6.90e-3)" "unprognostic (5.84e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (2.85e-3)" "unprognostic (9.23e-3)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.39e-4)" "unprognostic (1.23e-1)" "unprognostic (8.68e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" 53.4 44.7 53.6 40.1 70.6 68.1 50.2 73.4 81.3 55.3 43.1 43.9 44.5 41.0 24.5 29.1 47.3 24.6 32.9 47.9 58.9 30.2 35.2 38.9 55.3 58.6 58.3 66.1 23.9 34.4 24.4 41.0 61.2 35.9 32.5 55.3 36.3 33.4 81.4 45.4 40.7 24.8 55.1 55.1 30.0 25.8 58.3 71.8 33.7 63.4 39.9 32.0 44.5 91.2 37.1 16.6 94.5 16.6 32.0 18.0 46.1 31.5 53.8 46.0 56.4 47.7 40.4 0.3 12.5 19.6 16.6 34.2 44.9 16.7 41.1 62.4 31.5 28.8 46.5 53.2 42.5 24.5 18.6 19.8 35.3 15.2 44.0 107.8 27.8 54.5 31.5 101.6 16.6 45.9 32.7 35.3 38.0 32.1 16.8 25.2 30.9 63.1 22.5 38.6 35.6 58.4 48.9 34.8 65.8 33.7 18.6 54.6 19.1 22.6 34.9 20.7 33.3 86.1 59.4 33.2 28.2 36.6 22.5 6.2 3.8 8.6 5.9 3.5 6.1 6.8 7.7 7.2 3.6 5.0 8.0 6.1 20.9 7.3 5.5 3.9 12.3 4.0 53.6 70.6 73.4 81.3 47.9 58.9 58.6 58.3 61.2 55.1 58.3 91.2 64.2 44.8 29.3 6.2 126.2 52.6 20.7 21.0 115.5 45.6 39.5 30.1 39.1 21.5 27.1 9.2 27.1 42.9 92.5 32.3 15.6 10.8 70.0 31.2 35.8 51.1 45.7 70.5 8.1 9.3 47.6 39.3 25.5 34.3 31.0 21.3 47.2 30.7 26.8 10.1 13.4 41.4 24.4 55.3 66.0 67.7 55.9 65.1 74.7 23.4 31.6 182.9 60.8 6.0 29.5 10.1 21.3 26.7 121.2 30.3 33.4 16.9 36.4 29.4 92.1 20.2 53.5 7.7 10.8 102.3 52.6 39.0 166.1 20.9 41.9 22.7 CDKN1C "BWCR, BWS, KIP2, P57" ENSG00000129757 "Cyclin dependent kinase inhibitor 1C" P49918 11 2883213-2885775 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 206.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 575.3;Extravillous trophoblasts: 1531.7;Syncytiotrophoblasts: 2241.2;Theca cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 155.1;non-classical monocyte: 376.4" "Lineage enriched" "Detected in many" 14 "monocytes: 376.4" "Cell line enhanced" "Detected in many" "EFO-21: 12.0;HeLa: 12.8;RPMI-8226: 18.7;SH-SY5Y: 33.0;SiHa: 25.2;SK-MEL-30: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002924 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Nuclear bodies" Cytosol "HPA002924: AB_1079548" "unprognostic (5.49e-3)" "unprognostic (2.62e-1)" "unprognostic (9.82e-3)" "unprognostic (5.79e-3)" "unprognostic (4.15e-1)" "unprognostic (2.84e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-1)" "unprognostic (3.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.95e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-1)" "unprognostic (3.31e-2)" "unprognostic (8.53e-2)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" 127.4 182.9 8.2 3.3 38.0 1.7 92.5 43.3 18.7 73.7 6.5 48.1 1.4 70.6 0.2 29.9 70.7 0.8 82.6 11.7 18.8 149.5 8.3 34.5 0.2 55.1 33.5 206.4 28.5 0.2 27.8 28.1 45.0 33.1 0.2 0.5 21.7 1.5 60.3 26.6 25.0 0.4 31.8 20.6 54.1 8.6 34.3 0.2 17.0 0.9 0.4 75.0 49.4 95.3 0.1 0.1 1.6 0.0 0.4 0.5 1.8 0.3 0.6 0.3 0.0 3.3 0.4 0.0 12.0 0.2 0.1 0.5 0.3 0.3 0.1 5.6 1.2 0.1 12.8 0.0 3.3 0.0 1.4 2.4 1.6 0.0 0.2 0.1 0.3 0.1 2.7 0.8 0.5 0.1 0.0 6.0 10.6 0.5 4.0 2.2 0.0 18.7 0.7 0.0 3.5 33.0 25.2 0.3 15.2 0.9 0.2 2.8 0.4 0.0 2.2 0.0 0.1 7.3 0.0 0.1 0.0 1.8 6.8 9.1 1.2 0.9 0.4 155.1 1.8 0.0 0.4 0.6 26.9 0.3 1.0 0.3 2.2 0.0 376.4 0.2 0.7 14.7 8.2 38.0 43.3 18.7 11.7 18.8 55.1 33.5 45.0 31.8 34.3 95.3 357.3 3.2 5.8 1.0 11.6 10.7 81.7 4.9 30.7 11.9 81.0 150.5 45.3 61.5 10.8 31.3 6.2 575.3 46.9 20.3 15.6 9.8 176.5 38.8 101.5 100.8 106.5 0.8 0.6 0.6 1531.7 141.0 17.9 56.2 0.0 31.2 74.6 4.0 91.0 8.4 1.2 25.0 12.2 23.5 23.2 276.4 74.3 54.9 35.6 4.7 14.1 68.3 0.0 3.5 65.7 4.3 4.2 44.4 12.9 64.6 4.0 78.5 7.5 27.4 32.9 238.3 71.4 2.1 3.5 17.3 11.8 2241.2 25.1 781.8 15.2 71.8 CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967752-21995301 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7;pituitary gland: 33.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9" "Cancer enhanced" "Detected in all" "cervical cancer: 49.9;ovarian cancer: 57.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 37.4" "Group enriched" "Detected in many" 6 "B-cells: 15.6;T-cells: 37.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7" "Low region specificity" "Detected in some" "CAB000093, CAB000445, CAB018232, HPA047838" Enhanced Supported Nucleoli NA NA 18000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoli "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174" "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favorable (5.19e-4)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" 3.7 10.1 7.4 1.7 8.3 1.3 3.1 5.9 8.5 1.1 31.7 1.9 0.8 0.7 1.0 7.4 2.2 0.5 0.7 6.7 6.4 0.5 0.7 2.3 2.1 7.4 5.8 0.8 1.5 2.1 33.7 2.6 7.2 2.1 0.7 0.1 1.6 1.6 0.6 0.9 3.6 0.3 6.2 5.5 3.9 14.8 8.0 2.1 1.3 0.0 2.5 2.4 2.3 9.2 11.8 0.0 1.7 82.2 0.8 0.9 39.1 15.9 0.0 111.7 196.0 19.1 289.2 47.1 167.7 9.5 0.0 36.0 34.3 211.0 91.4 212.2 389.7 0.1 311.1 13.6 8.8 22.4 17.3 21.2 0.0 112.2 61.9 236.3 11.7 0.0 0.1 188.4 105.7 0.8 1.9 0.0 2.6 24.2 185.9 0.2 80.2 166.3 23.4 0.0 195.2 14.0 219.9 36.6 318.7 9.4 42.8 0.7 39.5 0.9 2.6 0.3 0.5 84.7 49.6 177.8 0.2 62.9 1.0 1.5 2.1 0.3 9.9 1.3 14.1 11.1 11.4 17.6 0.3 15.6 0.6 6.7 0.5 0.8 4.2 0.0 37.4 3.6 7.4 8.3 5.9 8.5 6.7 6.4 7.4 5.8 7.2 6.2 8.0 9.2 1.6 0.0 0.0 1.0 11.5 1.8 2.3 170.1 0.0 0.6 6.1 10.4 4.2 0.0 145.9 11.0 0.0 27.9 6.2 8.1 0.0 29.7 227.5 36.4 6.7 2.6 70.9 0.0 1.2 26.4 43.8 7.7 0.0 6.2 4.5 4.6 1.4 0.3 7.6 0.0 3.5 6.3 122.1 10.5 4.2 447.9 3.1 2.9 8.8 7.5 16.2 0.9 5.2 4.5 6.6 417.7 12.1 1.9 38.7 35.4 32.8 0.0 221.9 0.1 0.0 1.1 20.8 7.2 6.2 7.2 0.4 9.2 12.7 11.0 3.8 54.4 CDKN2C "INK4C, p18" ENSG00000123080 "Cyclin dependent kinase inhibitor 2C" P42773 1 50960745-50974634 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 98.4;lymphoid tissue: 96.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 73.5;Sertoli cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 273.1;U-937: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005303, CAB018398, HPA019057, HPA019764" Approved Approved Nucleoplasm,Cytosol NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB005303: AB_2078729, CAB018398: AB_2078731, HPA019057: AB_1854865, HPA019764: AB_1854866" "unprognostic (4.07e-2)" "unprognostic (1.47e-3)" "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "unprognostic (6.70e-2)" "unprognostic (4.76e-3)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (2.28e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.70e-10)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.24e-1)" 98.4 23.2 21.6 9.1 23.6 36.0 30.6 22.6 31.4 17.5 20.3 19.3 13.4 20.4 11.8 11.1 15.2 15.5 24.2 21.6 23.0 10.4 7.2 9.9 22.5 23.0 22.4 47.6 17.4 19.9 7.8 7.3 24.0 9.9 12.6 7.8 8.8 24.9 20.5 18.9 14.2 22.2 21.2 11.1 7.4 5.2 22.2 96.2 9.7 8.6 23.4 13.1 16.3 30.3 67.6 32.9 5.9 99.6 108.0 16.4 1.5 61.8 76.2 121.8 107.8 1.8 25.7 140.3 58.5 63.5 41.6 8.2 71.4 9.8 63.4 78.4 90.7 102.5 254.6 21.5 5.5 74.0 42.8 5.6 1.9 32.8 14.6 45.6 32.7 115.0 45.0 0.0 76.2 22.0 91.1 40.4 0.1 31.6 71.3 108.6 86.8 0.4 42.9 34.1 49.6 114.3 88.1 67.5 23.6 0.6 31.3 273.1 21.6 130.8 44.1 76.3 0.9 128.1 131.9 113.2 0.0 284.5 118.3 22.4 3.7 17.9 7.3 2.2 8.4 4.9 10.8 9.7 9.3 4.3 6.0 5.8 0.4 10.5 0.9 11.5 22.0 5.6 21.6 23.6 22.6 31.4 21.6 23.0 23.0 22.4 24.0 21.2 22.2 30.3 9.5 0.0 3.9 2.0 5.6 10.1 2.6 8.1 23.9 8.2 3.8 29.5 14.3 5.7 6.1 3.7 16.7 4.9 11.3 2.8 17.6 6.3 4.9 1.1 18.2 8.1 8.4 73.5 0.6 3.4 12.1 31.0 3.1 1.2 16.5 12.6 20.3 8.8 28.3 5.0 0.6 10.2 14.2 20.5 16.0 7.1 39.4 11.0 7.2 1.9 17.1 26.9 17.5 2.0 3.3 3.1 10.2 47.8 14.0 1.8 24.6 40.8 3.2 9.9 85.5 38.9 26.7 32.0 15.0 22.0 11.2 1.9 18.2 28.6 9.1 1.2 CDX2 CDX3 ENSG00000165556 "Caudal type homeobox 2" Q99626 13 27960918-27969315 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 41.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 287.5;Intestinal goblet cells: 214.5;Paneth cells: 181.7;Proximal enterocytes: 226.9;Undifferentiated cells: 194.4" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 63.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 14.4;CAPAN-2: 4.8;HEK 293: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002221, HPA045669, HPA049580" Enhanced Enhanced Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB002221: AB_563649, HPA045669: AB_2679413, HPA049580: AB_2680823" "unprognostic (1.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.92e-1)" "unprognostic (8.11e-3)" "unprognostic (4.19e-6)" "unprognostic (1.73e-4)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" "unprognostic (5.51e-2)" "unprognostic (6.07e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" 0.1 0.0 0.0 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.0 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 31.3 0.0 0.0 0.1 0.0 0.0 35.9 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.4 4.8 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 7.7 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 3.0 0.0 287.5 0.0 28.9 0.0 0.0 0.0 0.0 62.4 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 214.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.9 181.7 0.0 0.0 0.2 226.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.3 0.4 0.0 194.4 0.3 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 181.5;esophagus: 195.2;intestine: 220.3;lung: 286.7;salivary gland: 177.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 942.3;Club cells: 322.1;Distal enterocytes: 640.1;Paneth cells: 391.1;Urothelial cells: 182.3" "Group enriched" "Detected in many" 4 "cervical cancer: 139.4;colorectal cancer: 500.8;lung cancer: 344.1;pancreatic cancer: 437.5;stomach cancer: 231.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 11 "OE19: 1799.0" "CAB008370, HPA011041" Enhanced NA NA 86000000 "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB008370: AB_592067, HPA011041: AB_1078481" "unprognostic (1.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.42e-4)" "unprognostic (4.08e-1)" "unprognostic (8.71e-3)" "unprognostic (2.85e-1)" "unprognostic (7.68e-2)" 2.0 0.4 0.3 29.7 1.2 181.5 2.7 0.6 0.6 39.2 0.0 195.0 33.0 0.6 1.8 195.2 8.2 130.1 0.2 0.2 0.0 0.3 0.7 286.7 0.3 0.3 0.1 0.4 5.2 0.1 0.3 0.5 0.2 2.4 220.3 0.0 177.6 1.4 0.1 6.8 24.4 6.6 0.0 2.4 15.5 0.4 0.3 2.1 0.3 0.0 32.5 9.6 79.1 0.4 0.1 162.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 5.5 4.6 0.0 0.2 0.0 0.5 19.4 0.0 0.0 0.1 0.3 0.2 0.0 0.5 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.1 11.2 0.1 0.2 0.2 1799.0 4.5 0.1 0.0 0.1 1.0 0.7 1.8 0.1 0.0 4.2 0.0 0.2 0.6 1.9 0.4 0.2 0.3 0.5 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.5 0.1 0.0 3.1 0.3 1.2 0.6 0.6 0.2 0.0 0.3 0.1 0.2 0.0 0.3 0.4 0.0 942.3 84.5 0.0 2.3 0.0 4.9 17.9 0.0 0.0 3.5 2.0 0.2 75.8 322.1 0.0 0.0 0.0 0.0 640.1 0.0 77.0 0.2 0.4 0.1 1.3 5.4 0.0 0.1 16.3 0.0 1.3 1.5 0.8 7.0 0.0 0.4 0.3 0.0 0.0 0.1 102.3 14.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.7 391.1 0.0 0.0 24.2 5.7 0.0 71.8 0.0 0.0 0.0 9.9 0.0 0.1 15.6 0.0 0.0 1.2 0.0 31.7 182.3 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cell line enhanced" "Detected in many" "BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 98.7 2.9 16.2 5.7 17.9 22.6 67.7 18.3 26.9 8.7 10.4 21.0 21.2 2.9 0.8 20.9 4.3 3.0 2.8 15.7 18.8 3.6 194.7 25.5 9.1 27.4 22.4 1.3 9.7 26.8 2.6 16.0 21.3 8.8 11.5 0.6 9.8 3.4 19.1 118.7 20.8 2.5 25.7 7.7 12.5 1.0 24.5 4.1 6.5 4.5 6.3 8.7 14.8 34.8 2.5 5.1 0.1 7.1 55.8 0.0 196.9 0.1 1.5 0.1 0.0 24.8 0.1 0.0 3.0 0.0 1.1 9.4 5.8 0.6 0.0 35.8 7.2 0.1 0.1 110.9 0.9 36.6 42.1 2.2 25.4 0.0 0.2 0.0 0.0 2.8 2.4 0.0 0.0 12.7 0.2 114.1 5.0 61.8 2.7 0.0 0.4 1.1 0.2 17.7 0.4 1.7 0.7 0.5 0.8 6.2 13.7 407.7 0.1 0.1 0.8 0.1 0.9 0.4 0.0 0.2 0.0 130.9 0.0 16.0 7.1 0.0 0.8 12.3 0.7 0.0 0.1 0.5 5.1 0.1 0.2 0.4 2.5 0.0 15.7 0.2 0.0 2.1 16.2 17.9 18.3 26.9 15.7 18.8 27.4 22.4 21.3 25.7 24.5 34.8 5.4 16.0 37.8 0.0 2.8 37.3 20.8 3.3 22.2 0.7 6.2 12.2 0.4 57.2 5.1 0.0 0.0 40.3 14.4 91.6 3.9 0.5 0.0 0.8 0.8 4.9 4.2 5.7 1.9 5.8 44.3 9.5 12.8 1.3 1.3 0.0 2.2 106.5 87.0 0.0 0.3 24.8 4.1 35.0 27.4 0.2 3.1 42.9 5.4 17.8 28.2 8.4 6.2 1.0 0.4 1.9 30.6 1.5 2.0 15.1 42.5 4.9 5.1 0.5 0.0 4.1 3.1 0.2 0.7 29.7 171.8 212.3 5.0 0.3 51.5 12.2 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CEP43 "FGFR1OP, FOP" ENSG00000213066 "Centrosomal protein 43" O95684 6 166999317-167094789 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12.3;Cytotrophoblasts: 14.2;Extravillous trophoblasts: 16.2;Hofbauer cells: 10.3;Syncytiotrophoblasts: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071876 Approved Supported Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Centrosome "HPA071876: AB_2686467" "unprognostic (9.14e-2)" "unprognostic (2.24e-1)" "unprognostic (3.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" "unprognostic (9.59e-2)" "unprognostic (1.00e-1)" "unprognostic (6.95e-2)" "unprognostic (8.83e-2)" "unprognostic (1.08e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (3.15e-1)" "unprognostic (2.09e-3)" 6.9 14.8 8.8 12.6 8.3 16.7 14.3 8.3 10.0 13.5 9.2 12.4 15.9 14.9 16.9 9.0 27.0 11.2 8.9 8.1 8.3 17.4 36.3 7.3 14.8 8.7 11.4 13.0 11.3 10.5 14.1 8.4 9.4 9.4 16.9 25.4 8.8 9.1 8.5 11.6 15.8 10.4 7.7 11.1 11.3 58.4 8.4 15.7 15.5 10.4 17.7 9.2 9.3 9.4 26.1 14.3 35.3 24.2 20.3 15.1 42.7 33.0 21.9 26.4 25.3 53.1 21.6 31.0 18.3 20.2 70.3 24.0 31.4 23.3 49.3 19.5 27.0 21.4 26.7 58.2 10.8 38.4 21.6 8.4 16.8 54.2 25.2 16.4 18.5 34.5 70.9 25.8 34.2 24.0 31.1 55.8 30.2 50.0 10.9 35.3 23.9 25.7 27.8 13.8 26.2 26.2 26.9 28.6 11.7 24.6 23.5 46.7 12.2 26.1 43.7 31.6 42.1 21.8 32.3 31.4 29.4 35.4 32.7 0.4 6.5 23.5 5.1 6.1 7.6 12.1 5.8 4.8 10.7 8.4 3.4 5.5 38.8 6.3 6.7 16.4 11.7 4.9 8.8 8.3 8.3 10.0 8.1 8.3 8.7 11.4 9.4 7.7 8.4 9.4 3.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 14.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 16.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 6.3 1.3 0.0 0.0 0.0 CEP76 "C18orf9, FLJ12542, HsT1705" ENSG00000101624 "Centrosomal protein 76" Q8TAP6 18 12661833-12702777 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 209.7;Late spermatids: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 60.5" "Region enriched" "Detected in all" 9 "cerebellum: 55.0" "Region enriched" "Detected in all" 5 "cerebellum: 16.3" HPA039395 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA039395: AB_10673357" "unprognostic (3.39e-1)" "unprognostic (2.99e-2)" "unprognostic (2.26e-1)" "unprognostic (9.31e-3)" "unprognostic (1.65e-1)" "unprognostic (1.37e-1)" "unprognostic (2.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.00e-4)" "unprognostic (7.88e-3)" "unprognostic (2.45e-1)" "unprognostic (8.70e-2)" "unprognostic (1.67e-2)" "unprognostic (4.39e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-2)" "unprognostic (8.21e-2)" 3.0 3.4 2.5 2.6 2.5 6.2 3.8 7.7 3.3 3.4 2.6 2.9 2.7 3.3 5.1 5.3 2.7 2.6 2.7 2.3 2.5 3.1 4.8 2.7 3.8 2.3 2.4 3.2 2.3 2.5 2.2 3.4 2.5 2.8 3.9 4.5 2.9 2.8 3.2 4.0 3.1 3.3 2.3 2.5 2.8 8.2 2.6 7.9 3.7 3.5 4.7 3.2 2.8 2.6 7.3 7.2 12.1 5.9 7.1 3.8 11.7 8.4 9.4 16.1 12.5 16.6 8.5 9.7 7.3 5.5 9.4 5.6 12.1 5.3 13.7 6.1 9.8 8.5 8.0 14.1 5.3 20.0 9.5 3.0 5.3 9.5 6.2 4.5 8.5 13.5 14.5 14.3 10.4 5.5 17.5 13.9 8.7 60.5 4.7 12.2 10.5 10.4 8.4 7.1 9.2 8.0 10.5 6.7 6.9 7.9 4.8 11.0 8.0 10.8 21.9 10.6 10.0 8.0 14.8 11.5 5.4 9.7 7.2 0.4 2.3 2.1 2.6 4.4 3.5 1.8 2.9 3.2 2.1 2.3 2.9 3.4 0.7 3.7 1.7 1.2 3.5 2.2 2.5 2.5 7.7 3.3 2.3 2.5 2.3 2.4 2.5 2.3 2.6 2.6 4.3 6.4 5.9 7.5 7.2 9.7 3.9 3.0 5.2 6.3 4.1 4.6 1.8 1.5 5.4 0.0 12.5 5.9 6.7 3.7 1.9 3.0 209.7 5.5 5.8 5.2 6.0 13.9 16.9 2.5 7.5 4.0 2.0 4.6 5.7 14.0 4.2 4.8 4.1 3.3 16.7 5.5 4.1 3.5 4.1 57.8 3.7 3.4 7.2 3.7 2.5 2.9 6.2 7.5 7.9 3.8 0.6 4.5 10.3 5.1 7.8 2.5 3.5 8.0 6.6 7.1 3.7 27.7 22.1 12.4 8.2 6.2 6.4 11.5 4.8 5.7 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196832189 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 272 "liver: 2081.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 320.0" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HeLa: 1.2;HL-60: 2.0;U-266/70: 2.4" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" 1.5 0.6 0.1 1.8 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 7.6 2081.3 0.1 6.7 0.1 0.8 0.3 0.3 0.0 0.1 0.1 0.4 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.7 0.2 0.1 6.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.9 0.3 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.1 0.1 0.0 2.4 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.4 0.1 0.2 0.1 0.5 3.2 0.0 0.0 2.2 0.4 0.1 0.0 0.0 1.2 0.0 0.1 1.8 11.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 18.7 0.0 0.0 0.0 9.9 0.0 0.0 0.0 6.0 15.0 320.0 5.6 0.0 0.4 0.0 0.0 16.9 0.4 0.2 1.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 41.0 2.1 0.3 1.5 0.0 0.0 0.3 1.4 5.6 0.1 0.1 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 609.9;Urothelial cells: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 392.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 392.6" "Cell line enhanced" "Detected in all" "U-266/70: 214.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 122.4 50.6 38.8 103.9 40.9 247.6 83.1 54.1 47.4 57.0 75.6 86.0 59.2 57.9 60.6 68.0 66.6 71.6 184.8 39.4 32.7 57.5 59.2 174.6 91.1 46.5 40.5 38.3 40.7 31.8 29.4 94.0 42.1 65.6 56.4 12.4 58.0 63.2 222.8 51.0 64.8 58.8 36.6 98.1 56.5 25.3 51.9 54.1 78.8 89.2 107.3 78.7 61.7 46.1 21.5 42.9 30.0 17.9 92.3 71.0 37.5 53.6 92.1 34.3 41.6 50.4 78.4 5.8 49.6 62.5 41.6 15.5 9.8 40.3 53.9 160.7 29.9 32.3 38.4 82.2 63.6 24.2 102.2 76.8 39.6 58.2 50.3 41.7 176.7 7.3 110.8 131.2 63.1 17.9 11.3 96.3 10.2 17.2 32.7 11.7 7.2 46.5 42.5 44.0 6.6 11.8 35.7 31.2 43.2 19.6 22.1 44.8 193.6 71.0 29.5 26.7 26.1 214.6 76.2 35.9 50.6 19.5 36.3 91.8 60.3 70.3 54.4 61.8 48.4 25.6 46.5 52.1 33.4 20.9 29.5 38.3 392.6 45.2 68.5 23.0 60.7 42.0 38.8 40.9 54.1 47.4 39.4 32.7 46.5 40.5 42.1 36.6 51.9 46.1 191.3 451.9 234.9 30.3 126.4 54.8 229.6 164.9 29.0 10.9 38.9 30.0 205.8 102.9 206.7 69.9 31.3 77.2 166.2 132.5 74.3 148.8 83.3 202.8 75.0 261.0 95.1 59.1 6.9 72.5 34.8 89.5 73.4 219.2 81.6 93.4 201.0 97.5 68.6 13.5 16.8 76.8 40.7 123.2 609.9 44.8 51.9 278.0 97.8 146.1 247.0 23.4 276.0 29.7 56.8 166.4 155.6 49.7 317.8 386.0 116.7 101.5 276.1 30.7 39.5 113.2 77.9 14.4 12.2 33.2 86.1 70.1 168.3 56.1 50.9 521.3 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 CGA "FSHA, GPA1, GPHa, GPHA1, HCG, LHA, TSHA" ENSG00000135346 "Glycoprotein hormones, alpha polypeptide" P01215 6 87085498-87095106 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 4389.4" "Cell type enriched" "Detected in some" 15 "Syncytiotrophoblasts: 85317.2" "Cancer enhanced" "Detected in many" "breast cancer: 10.9;testis cancer: 13.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "BEWO: 776.1;SuSa: 1437.9" "Region enriched" "Detected in many" 6 "hypothalamus: 22.2" "Region enriched" "Detected in many" 40 "hypothalamus: 82.2" "CAB023350, HPA029698" Enhanced "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB023350: AB_617281, HPA029698: AB_2673153" "unprognostic (1.66e-1)" "unprognostic (2.10e-1)" "unprognostic (3.22e-5)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.69e-2)" "unprognostic (3.17e-1)" "unprognostic (7.04e-3)" "unprognostic (1.51e-1)" "unprognostic (2.85e-1)" "unprognostic (4.32e-2)" "unprognostic (8.32e-2)" "unprognostic (9.15e-3)" 0.8 4.1 0.2 0.1 0.4 1.9 0.1 0.7 0.7 0.0 0.3 0.3 0.5 1.0 1.2 1.2 0.1 0.2 1.5 0.3 0.3 2.7 2.0 0.7 0.3 2.1 1.6 0.5 1.3 18.9 4389.4 725.8 0.9 2.7 0.3 0.3 0.5 1.1 3.3 2.1 0.3 3.4 0.1 1.1 38.1 0.5 1.0 0.8 0.5 0.0 0.3 0.4 0.2 1.5 0.0 1.0 0.0 0.1 0.0 0.0 776.1 0.7 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.9 4.2 1.8 0.3 40.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.1 1.0 0.6 0.1 22.6 0.0 1437.9 0.1 0.0 0.0 0.9 0.2 0.4 0.3 3.1 0.4 0.5 0.2 0.0 0.1 0.7 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.3 0.1 0.4 0.2 0.4 0.6 0.2 0.3 0.4 0.1 0.0 0.2 0.4 0.7 0.7 0.3 0.3 2.1 1.6 0.9 0.1 1.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 1.9 0.0 0.0 7.3 0.0 1414.2 0.1 0.0 0.0 0.0 0.2 20.2 1.1 22.9 1.8 0.0 0.2 0.0 5400.7 65.5 0.0 28.4 0.0 0.0 0.0 0.0 625.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.0 85317.2 6.0 0.0 0.2 9.9 CHCHD7 "COX23, MGC2217" ENSG00000170791 "Coiled-coil-helix-coiled-coil-helix domain containing 7" Q9BUK0 8 56211686-56218809 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050783 Approved Approved "Cell Junctions,Aggresome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Cell Junctions" Aggresome "HPA050783: AB_2681236" "unprognostic (1.64e-2)" "unprognostic (3.23e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.46e-2)" "unprognostic (2.43e-1)" "unprognostic (5.04e-2)" "unprognostic (8.38e-3)" "unprognostic (1.62e-1)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "prognostic favorable (9.47e-5)" "unprognostic (1.94e-1)" "unprognostic (5.07e-1)" "unprognostic (1.77e-2)" "unprognostic (2.50e-1)" 24.9 20.2 25.8 30.0 27.1 29.2 25.8 30.8 32.5 22.9 25.2 30.7 33.2 18.6 46.0 22.8 24.5 17.1 41.6 26.6 26.6 42.2 26.2 28.0 39.4 27.0 26.3 49.1 26.9 36.0 38.1 19.3 27.3 26.4 30.2 32.6 35.3 21.0 37.5 21.3 36.0 18.5 28.6 46.3 27.7 11.7 26.7 36.5 28.0 39.7 38.1 28.1 24.2 28.7 59.3 18.9 39.4 13.1 100.9 71.3 42.4 41.0 37.0 30.7 23.0 46.2 68.9 54.7 34.8 23.6 43.6 32.3 40.7 61.3 38.6 24.5 77.4 83.6 45.5 66.2 51.8 72.1 52.0 86.2 54.2 22.2 98.0 43.8 32.8 100.0 41.8 34.9 74.1 29.0 72.2 106.5 35.1 93.5 25.6 82.0 12.0 46.3 57.3 63.3 10.2 7.0 21.8 32.2 31.2 47.8 34.1 40.5 49.0 16.5 35.4 53.7 39.5 37.1 40.3 93.5 46.0 105.3 28.9 55.2 37.8 53.3 42.4 38.2 40.2 60.4 46.9 43.5 44.1 52.5 55.0 49.6 15.2 49.7 35.0 62.6 60.1 33.9 25.8 27.1 30.8 32.5 26.6 26.6 27.0 26.3 27.3 28.6 26.7 28.7 31.7 19.2 77.9 2.6 72.5 20.8 44.1 49.0 16.5 31.4 37.1 27.1 93.7 35.8 48.0 49.7 14.6 44.0 66.0 75.4 125.2 41.4 27.5 25.2 15.9 29.8 39.6 32.6 9.1 75.4 80.8 26.3 92.8 32.2 53.8 13.8 42.8 78.4 162.3 13.5 8.0 66.3 34.6 67.8 45.3 13.4 37.0 58.0 53.4 14.0 68.5 50.8 60.8 1.5 6.5 65.4 63.9 30.9 59.3 45.3 115.0 82.3 41.5 37.9 13.1 23.9 39.0 51.4 39.4 34.7 23.9 42.1 61.7 21.7 73.5 48.8 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 34.5 45.6 22.9 38.6 30.7 44.4 31.9 24.6 30.1 39.4 20.6 45.7 26.5 47.8 44.9 35.4 37.7 31.1 41.4 19.7 26.1 39.3 31.6 35.3 46.3 27.3 29.2 40.9 37.7 58.3 33.5 42.2 28.0 28.4 35.4 44.9 33.8 44.1 50.0 45.8 35.5 49.9 22.6 39.0 38.5 34.2 29.6 90.7 54.6 38.7 56.6 42.2 34.4 27.4 86.7 79.7 187.6 72.1 76.6 84.7 110.4 92.9 93.4 102.3 93.5 130.6 66.6 184.9 36.0 107.5 66.1 76.0 179.1 104.5 135.7 139.9 92.7 258.5 122.0 83.3 67.1 207.2 119.1 82.9 51.7 99.1 68.7 128.2 122.2 101.6 209.0 91.0 98.7 111.8 196.6 67.8 184.7 82.5 72.7 166.4 114.9 103.6 64.2 101.6 88.8 114.6 121.1 136.0 92.9 205.4 61.3 121.3 114.4 103.4 217.4 76.3 111.5 144.0 91.8 230.2 68.7 125.8 79.5 12.3 6.8 8.7 9.3 7.7 9.6 8.8 8.4 9.3 6.9 11.3 10.6 10.3 10.8 12.2 8.0 14.4 15.9 5.6 22.9 30.7 24.6 30.1 19.7 26.1 27.3 29.2 28.0 22.6 29.6 27.4 68.2 60.9 119.7 56.2 82.8 68.6 47.4 42.4 76.2 109.9 77.5 61.2 132.9 58.6 67.2 88.3 70.9 48.2 106.0 58.1 13.7 84.6 76.4 128.1 153.3 78.9 97.1 64.4 26.1 71.9 46.1 67.7 47.9 123.7 85.9 73.0 56.0 69.2 69.0 139.7 21.4 66.6 54.9 51.9 78.3 59.1 65.9 68.9 48.0 25.3 66.7 71.4 56.7 24.6 55.5 95.8 36.4 74.4 69.0 49.4 45.8 38.3 82.1 57.8 52.6 112.1 98.1 102.6 111.6 78.9 67.6 68.0 85.1 83.7 72.1 47.4 CHD7 "CRG, FLJ20357, FLJ20361, KIAA1416" ENSG00000171316 "Chromodomain helicase DNA binding protein 7" Q9P2D1 8 60678740-60868028 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 241.8;Oligodendrocyte precursor cells: 298.6;Oligodendrocytes: 255.7;Rod photoreceptor cells: 198.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "B-cells: 14.9;granulocytes: 17.6;T-cells: 6.6" "Cell line enhanced" "Detected in many" "AF22: 51.5;SCLC-21H: 46.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053075 Supported Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Nucleoli "HPA053075: AB_2682035" "unprognostic (3.77e-2)" "unprognostic (3.28e-3)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.34e-5)" "unprognostic (9.59e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-3)" "unprognostic (3.41e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (9.09e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-1)" "unprognostic (8.20e-2)" "unprognostic (2.17e-1)" 3.6 1.9 10.3 3.9 17.2 22.1 3.5 71.5 11.0 2.0 2.5 4.6 4.6 2.2 2.2 4.9 2.3 1.9 3.8 9.4 11.5 3.8 3.2 4.6 5.8 19.7 17.2 1.0 4.4 5.3 6.1 4.3 18.8 2.7 4.0 23.7 3.9 1.7 10.4 5.2 6.4 1.7 11.4 5.6 3.5 2.9 15.6 2.6 4.1 4.1 5.7 3.4 3.2 17.7 8.0 4.0 51.5 9.2 0.1 0.0 16.2 0.4 0.1 1.8 1.6 10.0 7.3 15.5 0.9 0.1 2.3 4.8 26.7 7.9 1.6 5.9 14.3 36.5 7.0 13.2 2.1 11.1 6.5 1.0 5.9 0.0 8.5 3.1 7.7 12.5 2.7 13.4 1.2 8.3 17.5 12.7 35.4 8.1 1.8 36.0 12.1 5.0 4.1 9.1 46.9 23.2 1.4 5.9 14.9 18.0 10.5 10.5 9.0 0.5 8.3 0.5 4.3 14.2 8.7 23.7 3.0 1.2 13.4 14.9 0.4 17.6 3.2 0.2 4.1 10.1 3.6 1.1 0.1 14.9 6.6 2.4 9.3 0.0 0.8 0.8 0.3 0.6 10.3 17.2 71.5 11.0 9.4 11.5 19.7 17.2 18.8 11.4 15.6 17.7 35.9 32.1 17.5 68.6 64.3 30.3 35.9 10.8 9.6 36.3 16.6 14.6 35.8 27.1 20.7 16.5 241.8 8.2 17.4 31.8 1.9 17.7 15.9 34.0 4.1 40.5 87.3 3.8 6.8 11.3 8.6 6.4 28.5 37.6 41.0 39.8 21.4 12.6 14.9 70.7 17.8 39.9 32.6 10.8 10.4 8.9 0.9 13.6 21.4 118.0 13.9 121.3 15.5 298.6 255.7 16.9 27.4 0.4 29.1 42.9 17.4 5.4 20.4 198.5 0.0 49.7 9.8 8.0 12.9 25.5 32.4 6.2 21.4 3.0 34.1 35.8 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA052186: AB_2681754, HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favorable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 12.5 11.9 11.2 13.5 12.5 35.3 14.8 16.3 13.2 12.4 10.5 14.0 9.4 14.8 11.1 14.9 12.9 10.1 12.0 11.1 12.2 11.7 9.6 13.7 18.0 11.4 11.6 17.1 13.6 22.3 13.1 11.7 11.1 13.2 12.3 14.8 13.6 12.1 15.7 22.3 14.7 14.8 11.5 15.8 14.2 12.9 12.5 25.4 14.8 12.7 17.5 12.8 12.9 13.6 31.2 39.6 43.6 20.7 27.7 23.6 24.9 24.4 28.4 36.5 35.4 35.0 26.3 51.4 14.8 33.1 28.4 37.2 54.9 35.1 46.0 39.3 24.2 46.3 27.6 43.5 25.7 64.6 40.4 32.8 27.2 40.9 29.7 28.6 33.4 40.2 32.4 26.7 28.0 33.9 46.1 26.0 33.4 30.9 34.3 42.0 32.9 17.4 27.3 57.9 30.9 30.7 37.5 29.8 21.8 39.7 20.7 30.5 36.4 29.2 23.0 17.8 29.1 30.3 38.4 50.3 12.1 23.2 29.6 9.1 3.8 9.8 5.5 3.8 6.4 4.2 4.9 5.6 2.7 11.2 5.0 4.4 7.9 7.8 6.7 6.1 4.7 2.7 11.2 12.5 16.3 13.2 11.1 12.2 11.4 11.6 11.1 11.5 12.5 13.6 27.6 38.5 56.3 27.4 32.2 12.6 11.3 15.9 23.3 33.3 21.9 22.6 19.6 24.3 32.6 33.1 27.1 14.7 40.0 16.8 1.9 21.8 3.4 32.5 37.9 25.5 27.1 27.8 41.0 23.6 12.3 24.0 27.5 39.5 28.4 41.7 13.9 14.9 17.5 23.5 40.2 16.0 8.2 20.1 9.3 4.1 16.1 25.3 10.6 20.6 27.1 18.9 32.0 29.7 33.1 26.5 13.9 17.7 32.4 16.1 12.0 7.4 28.8 24.3 0.0 32.1 26.2 29.2 25.1 24.6 16.6 12.3 31.4 34.1 16.8 12.7 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625665-125676255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 20.7;seminal vesicle: 29.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Erythroid cells: 34.5;Extravillous trophoblasts: 35.6;Spermatocytes: 48.9;Spermatogonia: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 1.7;T-cells: 6.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 1.6 1.3 0.7 8.2 1.0 25.7 2.6 0.6 1.3 1.7 0.5 7.9 6.8 1.7 6.7 4.1 1.1 1.7 0.9 0.7 0.9 2.2 2.1 1.3 14.9 0.7 0.8 1.8 2.0 13.2 1.7 4.8 0.8 1.6 8.7 0.7 1.5 29.8 0.6 3.6 7.3 3.4 0.6 2.2 2.6 8.9 1.2 20.7 1.0 1.3 13.9 3.3 2.1 0.8 48.5 37.0 81.1 47.4 13.5 28.9 35.7 61.1 28.7 41.6 40.1 88.0 100.3 120.7 63.5 24.9 53.7 52.6 54.2 33.2 50.1 81.4 24.8 224.2 27.2 44.7 4.3 121.1 39.6 15.7 6.0 47.6 36.0 19.9 44.7 84.1 117.3 102.7 51.4 23.8 181.3 65.0 86.1 77.1 33.2 104.7 74.4 67.2 37.9 63.2 50.5 53.6 45.2 35.4 15.2 57.3 93.9 40.6 28.4 51.0 47.3 29.6 60.8 21.9 45.4 187.5 20.5 86.6 67.6 1.7 0.2 0.0 0.4 0.1 0.2 0.7 1.6 0.4 0.6 0.3 0.4 0.3 1.1 0.3 0.1 0.7 6.2 0.4 0.7 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.8 0.6 1.2 0.8 1.1 3.2 0.5 1.6 5.5 6.2 3.9 5.8 5.2 1.7 3.9 6.0 4.6 32.9 4.1 7.3 0.0 17.3 6.0 4.5 3.9 3.4 7.8 5.5 8.0 3.5 1.8 34.5 3.3 1.1 35.6 5.3 6.1 9.9 0.0 21.1 3.6 1.2 11.1 0.0 2.5 9.2 2.0 0.0 5.2 3.1 1.5 3.2 0.0 2.8 3.2 2.8 3.1 1.5 1.6 2.9 3.9 1.2 17.7 3.1 8.0 9.4 2.5 1.7 0.0 3.1 7.8 48.9 49.8 9.5 4.8 7.8 5.1 4.8 16.7 3.0 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 4.5 6.2 2.4 8.8 2.5 15.4 5.8 2.4 3.7 5.0 2.8 8.8 6.3 4.1 7.3 7.2 3.7 4.7 4.2 2.3 2.8 4.5 6.3 4.4 12.1 2.6 2.6 8.2 2.3 1.3 2.7 7.8 2.8 4.1 10.9 0.4 3.2 3.8 1.3 6.7 7.0 4.8 2.6 6.7 4.1 8.5 2.8 9.4 3.3 1.1 12.0 6.8 5.0 2.9 30.7 9.7 31.1 32.4 10.1 42.7 18.7 15.2 19.9 18.7 27.8 29.1 21.8 36.3 13.0 11.5 21.6 32.1 42.7 29.0 25.0 24.6 31.2 45.3 25.5 46.2 9.4 33.4 38.0 18.6 13.5 25.0 23.0 14.1 25.4 29.4 30.5 33.9 19.8 39.2 24.6 61.5 40.6 41.3 21.6 52.6 18.2 42.7 17.1 11.2 17.8 9.7 16.7 31.4 17.4 22.8 22.6 32.2 7.8 17.1 19.4 14.3 9.1 21.8 28.3 65.4 17.1 34.9 21.0 9.9 4.0 1.2 1.1 8.1 2.4 11.9 2.1 2.1 8.2 7.8 4.0 2.6 0.6 3.4 4.1 6.1 2.8 3.6 2.4 2.5 2.4 3.7 2.3 2.8 2.6 2.6 2.8 2.6 2.8 2.9 2.3 9.6 4.8 2.9 5.5 6.4 5.3 8.3 8.6 1.1 3.2 3.9 1.8 0.0 5.0 1.8 0.0 15.4 1.1 3.8 0.0 1.8 7.0 2.9 10.1 3.0 1.2 11.2 2.9 1.4 13.6 12.4 5.1 7.0 3.8 7.4 2.5 1.3 9.7 0.0 1.2 5.3 8.2 2.4 8.5 1.2 6.2 5.1 1.8 2.8 3.9 0.8 6.2 0.0 1.0 1.0 4.7 4.5 11.4 2.7 3.0 3.9 2.9 1.1 0.0 10.2 3.0 6.7 31.2 8.3 2.3 3.4 3.3 5.7 10.0 4.5 CHFR "FLJ10796, RNF196" ENSG00000072609 "Checkpoint with forkhead and ring finger domains" Q96EP1 12 132822187-132956304 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 93.8;Late spermatids: 89.1;Rod photoreceptor cells: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045768, HPA073826" Approved Uncertain "Nuclear bodies,Microtubules" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear bodies, Microtubules" "HPA045768: , HPA073826: AB_2732242" "unprognostic (1.46e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (3.86e-2)" "unprognostic (2.08e-1)" "unprognostic (2.14e-3)" "unprognostic (6.56e-4)" "unprognostic (1.94e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.00e-2)" "unprognostic (3.98e-3)" "prognostic unfavorable (4.21e-9)" "unprognostic (5.03e-1)" "unprognostic (8.46e-2)" "unprognostic (6.71e-2)" "unprognostic (1.11e-2)" 9.8 8.1 7.8 15.6 7.9 22.0 9.1 7.1 9.1 9.8 6.0 12.4 15.9 10.7 3.3 15.6 8.7 9.9 10.7 6.9 7.0 8.6 9.0 12.2 20.9 7.9 7.3 6.2 11.9 7.6 9.4 17.7 7.9 9.9 8.5 6.3 9.4 9.6 8.0 12.3 15.0 12.6 6.0 17.5 12.9 15.4 8.6 25.2 9.1 9.2 13.8 14.4 10.8 9.1 11.0 24.1 19.3 1.6 16.8 21.3 41.0 23.4 17.9 23.7 22.7 20.6 8.7 0.2 21.6 25.3 16.7 18.6 2.1 21.5 12.2 1.3 21.0 36.5 16.7 24.4 42.0 1.2 67.5 32.4 20.0 19.6 13.5 15.5 30.1 2.8 15.9 0.0 16.7 40.4 24.5 25.3 27.4 20.9 19.8 2.9 2.5 11.4 15.3 49.4 20.8 28.2 18.2 20.0 17.8 22.5 34.4 36.2 33.3 1.2 4.7 11.8 7.7 37.0 0.1 4.2 0.0 6.8 21.7 38.3 25.5 35.5 16.7 29.6 15.8 10.5 13.2 17.8 20.7 6.4 12.0 13.3 34.8 23.2 31.5 10.6 21.5 19.3 7.8 7.9 7.1 9.1 6.9 7.0 7.9 7.3 7.9 6.0 8.6 9.1 11.2 12.8 19.5 20.5 17.2 6.1 7.9 6.0 4.6 22.1 8.2 5.7 9.9 4.3 15.3 7.3 93.8 12.3 29.4 17.9 9.8 10.2 53.0 11.1 14.3 13.1 21.1 13.0 33.4 13.8 15.7 10.8 28.1 12.2 66.4 14.4 11.4 7.7 19.4 21.9 32.0 10.2 14.2 21.7 9.3 89.1 7.5 22.0 10.6 24.4 29.4 8.8 40.2 18.1 31.3 16.9 11.4 8.6 24.2 11.2 11.7 4.4 10.8 117.9 19.7 9.2 10.7 19.0 24.6 11.1 9.7 23.7 24.2 16.1 8.6 13.8 CHGA ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6568.4" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 6553.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 114.8" "Group enriched" "Detected in many" 16 "cerebral cortex: 326.0;white matter: 124.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 151 "SCLC-21H: 489.5;SH-SY5Y: 1339.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 295000000 100000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: AB_2081135, CAB058688: AB_2665574, HPA017369: AB_1846698" "prognostic favorable (7.85e-5)" "unprognostic (4.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (4.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.85e-1)" "unprognostic (8.81e-13)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (3.99e-4)" 14.5 1248.5 8.6 9.4 11.4 0.2 0.3 0.0 326.0 8.3 0.0 92.0 242.7 0.4 0.3 1.0 1.1 0.2 0.2 4.4 1.7 1.0 0.4 1.6 0.1 14.4 0.0 0.2 102.5 6568.4 446.2 0.0 4.1 12.2 105.2 11.0 0.2 0.3 0.1 0.6 179.9 0.9 0.0 0.1 364.5 77.7 4.3 0.6 24.6 0.0 0.0 1.3 1.2 124.4 0.0 0.5 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 2.7 0.0 0.0 0.2 0.0 1.4 0.0 0.0 489.5 1339.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 4.2 0.3 0.4 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 11.4 0.0 326.0 4.4 1.7 14.4 0.0 4.1 0.0 4.3 124.4 0.1 0.0 0.0 11.1 1.0 0.9 0.4 0.0 0.0 17.3 0.2 0.3 2.9 0.0 0.0 0.0 29.2 0.3 0.0 9.8 0.0 0.1 1.3 6.0 2.3 0.8 6553.1 0.0 59.5 0.4 0.1 4.1 195.7 0.5 0.0 0.5 0.0 0.0 1.5 16.8 37.7 820.4 14.2 0.0 0.0 7.9 39.7 0.1 7.2 15.9 2.0 3.7 0.0 10.6 12.8 46.5 137.8 137.3 0.0 6.6 36.7 0.0 0.0 16.2 0.0 0.0 0.2 4.7 2.2 0.0 0.0 0.3 0.2 0.4 25.9 5.1 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 305.0;skin 1: 149.7" "Group enriched" "Detected in some" 5 "Distal enterocytes: 345.0;Paneth cells: 274.0;Proximal enterocytes: 654.2;Undifferentiated cells: 205.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 7.3;hTERT-RPE1: 10.2;NB-4: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (4.82e-1)" "unprognostic (3.40e-1)" "unprognostic (4.93e-2)" "unprognostic (1.01e-2)" "unprognostic (8.85e-2)" "unprognostic (3.54e-1)" "unprognostic (4.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-5)" "unprognostic (2.21e-1)" "unprognostic (5.97e-2)" "unprognostic (7.84e-2)" "unprognostic (9.01e-2)" 0.4 0.2 1.1 3.8 1.1 2.2 4.3 3.6 1.3 14.0 0.0 146.7 305.0 0.9 1.1 0.6 0.9 0.4 0.4 0.7 1.6 4.1 0.7 0.6 0.8 0.5 0.1 0.4 0.5 0.1 0.0 1.4 0.9 3.8 147.4 1.3 0.8 4.5 1.2 149.7 250.5 6.5 0.1 0.3 1.1 7.3 0.9 0.5 0.6 0.2 0.4 9.0 4.2 2.9 1.0 2.2 0.5 0.6 1.2 1.3 1.2 2.9 1.1 0.3 1.0 0.5 2.3 0.4 0.9 2.5 1.2 1.4 0.4 2.9 0.6 0.7 0.2 0.5 4.1 1.6 1.7 0.3 0.7 0.9 0.8 2.5 7.3 10.2 1.1 0.3 1.2 1.0 1.2 0.1 0.1 8.7 0.3 0.5 2.1 0.2 0.1 1.4 1.1 0.7 0.6 0.7 0.8 0.2 0.0 0.6 0.2 0.2 1.3 0.5 0.6 0.7 0.1 0.4 0.1 0.2 0.0 0.5 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.1 0.1 0.0 0.0 1.1 1.1 3.6 1.3 0.7 1.6 0.5 0.1 0.9 0.1 0.9 2.9 0.0 0.0 0.0 0.0 0.0 10.3 8.7 6.1 0.0 0.0 0.0 0.1 0.1 0.0 24.4 1.8 0.0 0.9 0.0 345.0 0.0 0.0 0.6 1.3 0.5 0.2 9.1 0.0 0.0 0.0 4.1 0.2 0.0 3.6 4.5 0.7 0.0 0.0 0.1 0.0 0.0 70.0 12.2 0.0 1.6 0.5 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 274.0 0.0 0.0 2.5 654.2 12.9 4.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 67.5 0.7 0.2 0.2 205.4 29.9 CIB2 "DFNB48, KIP2, USH1J" ENSG00000136425 "Calcium and integrin binding family member 2" O75838 15 78104606-78131535 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 47.7;lymphoid tissue: 47.8" "Group enriched" "Detected in many" 4 "Early spermatids: 73.1;Late spermatids: 269.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in single" 48 "dendritic cells: 18.7" "Cell line enhanced" "Detected in many" "AN3-CA: 44.0;GAMG: 39.0;HAP1: 38.6;SCLC-21H: 38.8;SH-SY5Y: 40.1;SuSa: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036697 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "HPA036697: AB_10672475" "unprognostic (5.77e-2)" "unprognostic (1.83e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.46e-1)" "unprognostic (2.57e-1)" "unprognostic (1.11e-2)" "unprognostic (6.73e-3)" "unprognostic (1.66e-1)" "unprognostic (9.94e-3)" "unprognostic (3.18e-1)" "unprognostic (7.49e-2)" "prognostic favorable (6.16e-4)" "unprognostic (9.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" 7.0 12.1 16.7 3.1 16.9 1.6 4.8 15.9 22.9 13.1 13.8 9.6 18.7 9.1 3.1 4.0 5.7 2.8 47.7 18.1 17.4 9.1 1.2 3.0 3.5 20.1 18.3 7.3 5.9 13.4 10.4 3.7 20.1 10.4 7.1 5.0 8.1 8.7 11.4 6.8 24.6 6.6 17.5 3.0 3.9 23.3 16.9 47.8 4.0 1.9 6.5 8.6 7.8 16.2 3.5 8.6 24.2 44.0 1.1 1.4 18.1 2.4 0.9 2.0 4.2 0.0 9.6 0.4 4.8 11.3 39.0 1.9 38.6 7.7 0.6 21.7 26.8 2.6 1.6 1.4 4.3 0.0 3.4 2.1 3.2 3.5 2.0 5.0 4.2 13.0 9.1 0.2 3.7 0.7 1.1 0.4 31.1 1.2 0.3 16.9 0.1 1.0 2.8 0.7 38.8 40.1 5.9 3.1 3.5 49.2 0.6 2.6 0.3 0.1 20.3 2.2 0.3 0.4 0.4 6.7 1.0 0.1 5.4 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 18.7 0.0 0.2 16.7 16.9 15.9 22.9 18.1 17.4 20.1 18.3 20.1 17.5 16.9 16.2 11.0 0.0 0.0 1.6 3.6 5.5 26.6 2.3 1.8 2.9 3.4 12.6 11.4 1.5 0.5 1.8 6.2 19.4 17.3 14.9 9.8 3.0 73.1 1.6 8.1 3.0 3.0 3.0 1.6 1.1 15.5 9.5 2.0 1.5 0.0 10.7 2.5 0.4 2.8 5.0 3.9 25.1 2.0 0.6 1.4 269.9 3.4 2.3 7.2 1.0 0.1 18.1 1.0 2.5 0.4 1.5 16.2 2.6 1.7 12.3 35.9 10.6 0.2 2.2 6.6 11.5 4.9 10.0 17.5 0.4 3.1 9.3 2.5 18.0 11.1 11.5 CIC KIAA0306 ENSG00000079432 "Capicua transcriptional repressor" Q96RK0 19 42268537-42295797 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026388, HPA044341, HPA064725" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Vesicles "CAB026388: , HPA044341: AB_2678901, HPA064725: AB_2685335" "unprognostic (2.02e-2)" "unprognostic (4.08e-1)" "unprognostic (1.41e-2)" "unprognostic (3.54e-3)" "unprognostic (3.67e-1)" "unprognostic (4.17e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-1)" "unprognostic (1.85e-2)" "unprognostic (1.72e-3)" "unprognostic (3.10e-1)" "unprognostic (4.23e-2)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-1)" 41.9 41.5 43.3 23.4 36.1 31.8 42.7 40.7 47.4 53.8 2.3 45.6 15.6 62.3 8.7 34.3 49.1 16.1 35.4 36.3 27.7 41.7 44.6 40.8 24.2 39.5 27.8 70.1 39.4 12.2 58.7 12.6 35.7 40.5 5.8 13.5 35.4 18.7 45.2 47.2 36.9 16.0 17.4 46.9 38.6 74.6 29.4 21.0 44.3 15.3 13.5 39.6 37.5 32.5 31.8 56.7 26.4 34.4 16.6 30.7 10.7 22.8 22.5 22.9 20.9 18.5 21.4 26.7 20.8 21.8 19.6 16.6 14.6 38.9 7.6 61.9 19.6 22.2 44.7 23.0 20.1 11.8 50.9 36.7 25.5 24.4 15.5 24.8 19.2 15.9 21.8 52.5 13.3 31.9 25.1 25.6 16.2 12.6 5.8 21.5 21.2 14.3 20.5 25.3 33.6 27.1 23.7 15.7 21.6 8.3 18.3 25.8 27.5 52.0 43.7 15.9 33.2 41.0 29.8 18.1 37.9 19.4 32.6 0.0 0.5 0.1 0.7 0.8 0.5 0.5 0.3 0.5 0.5 0.6 0.2 0.4 1.1 0.2 0.6 0.6 0.1 0.6 43.3 36.1 40.7 47.4 36.3 27.7 39.5 27.8 35.7 17.4 29.4 32.5 27.8 0.0 3.0 15.7 13.7 25.9 12.8 16.2 27.9 38.3 20.7 16.9 7.8 21.5 7.1 9.2 20.9 6.9 9.1 14.2 3.9 13.4 5.1 14.6 14.9 20.3 14.8 8.4 8.0 15.3 5.1 11.2 17.9 22.3 12.0 11.1 13.9 19.2 11.9 42.1 9.0 10.1 10.2 18.0 23.6 3.3 21.8 15.3 24.9 7.5 13.0 18.4 8.2 4.0 10.3 16.9 11.2 18.0 10.4 11.3 10.6 6.2 8.0 18.8 26.3 19.9 17.6 19.4 20.2 16.5 19.5 13.0 13.2 14.2 10.6 11.9 CIITA "C2TA, MHC2TA, NLRA" ENSG00000179583 "Class II major histocompatibility complex transactivator" P33076 16 10866222-10943021 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.3" "Cell type enhanced" "Detected in many" "B-cells: 48.8;Langerhans cells: 51.8;Macrophages: 43.8;Microglial cells: 42.2;monocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 29.1;eosinophil: 17.5;intermediate monocyte: 23.5;memory B-cell: 47.3;myeloid DC: 46.2;naive B-cell: 63.3;non-classical monocyte: 29.0;plasmacytoid DC: 48.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 51.1;REH: 89.5;U-266/70: 18.0;U-698: 25.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016084, HPA054757" Enhanced Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB016084: AB_627261, HPA054757: " "unprognostic (1.45e-3)" "unprognostic (1.38e-2)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" "unprognostic (5.66e-2)" "unprognostic (2.88e-3)" "unprognostic (2.92e-2)" "unprognostic (1.55e-2)" "unprognostic (1.15e-2)" "unprognostic (1.85e-1)" "unprognostic (1.23e-1)" "unprognostic (3.72e-1)" "unprognostic (1.64e-2)" "unprognostic (2.72e-2)" "unprognostic (6.33e-3)" "unprognostic (2.74e-1)" "unprognostic (1.05e-2)" 9.4 6.5 6.4 39.2 5.9 9.2 7.8 7.3 7.9 10.7 8.9 6.7 20.5 7.3 2.6 5.5 7.4 15.0 5.4 5.4 11.5 7.2 4.7 24.1 57.3 15.0 8.3 3.6 3.9 2.6 3.0 2.6 11.9 4.8 8.2 1.4 12.1 6.9 5.0 8.7 24.8 7.3 11.5 51.2 12.9 2.1 13.0 15.9 5.2 2.4 57.0 9.0 4.1 16.4 0.4 0.4 0.7 0.6 0.1 0.0 0.5 0.2 0.0 0.3 0.4 0.6 12.0 11.2 1.6 0.0 1.7 1.8 0.0 0.0 0.2 51.1 0.6 6.3 2.6 1.3 0.0 0.9 0.9 2.1 0.0 0.2 0.0 1.8 0.0 0.7 0.8 4.1 0.2 0.7 0.6 1.0 0.3 0.4 0.3 89.5 0.6 7.9 0.1 3.6 1.8 0.3 2.1 0.6 2.1 0.6 1.0 3.8 0.5 4.3 0.7 1.2 0.5 18.0 1.4 25.8 16.0 1.1 14.7 0.7 29.1 17.5 0.8 23.5 0.4 47.3 0.3 1.4 46.2 63.3 0.2 0.4 6.8 1.8 29.0 48.3 1.2 5.4 6.4 5.9 7.3 7.9 5.4 11.5 15.0 8.3 11.9 11.5 13.0 16.4 14.5 6.4 19.5 0.3 48.8 2.3 0.3 1.3 1.2 0.8 1.7 2.0 5.3 1.5 1.5 3.7 0.0 0.2 17.9 2.0 0.0 5.5 0.8 1.5 0.4 7.3 2.4 6.9 1.4 2.0 0.3 1.2 4.6 1.4 10.8 7.7 1.4 0.7 8.7 0.0 1.8 1.9 0.0 16.1 51.8 0.0 0.6 43.8 7.2 42.2 51.8 0.2 2.1 0.0 0.3 1.1 0.1 0.0 1.1 0.4 12.3 4.8 5.6 1.6 0.0 1.0 1.2 0.0 0.0 1.0 2.8 0.1 3.0 0.4 1.5 0.5 CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 694.7;intestine: 653.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 2767.4;Distal enterocytes: 4691.8;Distal tubular cells: 2281.3;Horizontal cells: 5042.4;Muller glia cells: 3639.8;Rod photoreceptor cells: 3789.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 290.8" "Lineage enriched" "Detected in many" 18 "monocytes: 290.8" "Cell line enhanced" "Detected in many" "CACO-2: 455.8;HEK 293: 1399.8;SCLC-21H: 792.2;SH-SY5Y: 352.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB047313: , HPA001254: AB_1078528" "unprognostic (9.97e-2)" "unprognostic (1.33e-3)" "unprognostic (4.25e-3)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (3.62e-2)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (4.24e-1)" "unprognostic (4.60e-2)" "unprognostic (2.68e-3)" "unprognostic (9.89e-3)" "prognostic favorable (4.02e-8)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.67e-2)" "unprognostic (2.13e-1)" 90.7 60.0 471.6 25.8 627.0 3.2 47.2 641.1 694.7 105.2 192.7 653.4 36.0 222.6 16.0 54.5 197.9 17.9 269.8 428.7 482.3 161.0 9.0 60.3 4.0 427.5 440.4 58.8 27.7 108.2 74.0 4.7 345.1 301.8 151.9 471.3 37.9 208.3 80.0 76.5 120.8 113.8 434.5 6.8 479.9 97.6 596.2 2.8 87.9 47.1 5.1 298.4 101.6 383.6 2.4 54.5 321.1 14.7 4.4 2.3 6.3 37.5 0.3 2.4 1.4 455.8 7.3 0.4 36.9 29.1 9.9 70.2 109.9 1.5 0.2 9.6 1399.8 111.0 242.1 165.4 16.6 0.7 87.9 14.7 0.6 3.9 0.8 3.3 0.0 5.1 198.7 3.7 4.8 20.0 2.3 3.9 109.1 48.3 213.6 13.9 6.8 275.9 65.9 2.5 792.2 352.2 65.3 10.6 25.2 21.6 21.1 40.9 2.2 1.5 56.3 4.7 147.3 21.1 2.7 7.2 6.4 2.1 14.1 2.4 0.5 14.6 0.3 28.5 0.4 0.0 0.2 0.1 16.4 0.2 0.1 0.5 1.0 0.2 290.8 0.0 0.7 6.0 471.6 627.0 641.1 694.7 428.7 482.3 427.5 440.4 345.1 434.5 596.2 383.6 14.8 195.5 103.5 515.8 13.5 153.7 296.2 257.6 56.3 2767.4 41.5 48.9 553.5 145.8 117.9 114.0 1909.9 4.4 3.4 4691.8 2281.3 127.6 445.8 773.2 205.7 60.8 467.1 9.9 178.0 42.5 11.7 96.6 359.4 408.5 28.6 476.1 74.6 9.2 8.2 5042.4 147.0 726.0 187.2 2.8 44.9 147.4 304.1 39.8 181.5 88.1 74.2 3639.8 0.0 93.5 161.2 131.4 1996.9 1089.3 6.6 279.8 9.5 118.0 456.1 3789.9 59.2 15.4 222.6 127.3 97.4 22.1 175.2 41.6 19.1 12.2 755.6 220.1 CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (1.06e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.34e-1)" "unprognostic (2.59e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.01e-3)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.63e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (3.19e-1)" "prognostic unfavorable (6.03e-7)" "unprognostic (3.12e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.37e-1)" 59.0 31.9 15.0 33.6 15.8 117.7 67.8 16.4 19.8 44.3 15.0 49.4 40.8 35.0 36.8 61.6 40.9 22.2 35.5 15.4 16.2 37.9 73.3 29.0 71.3 17.5 15.8 31.7 22.4 35.5 18.4 50.6 17.7 26.1 50.5 6.0 28.4 32.9 14.5 51.2 44.3 34.8 17.4 37.0 35.5 48.6 15.7 88.7 30.1 23.5 74.1 30.1 42.6 18.8 459.2 616.5 455.9 245.3 66.9 68.1 361.4 209.1 166.8 463.4 367.8 599.9 653.4 433.8 345.9 143.2 251.2 410.6 468.0 305.2 428.7 392.9 293.9 294.6 249.9 426.5 19.4 359.7 257.9 39.8 132.2 391.4 532.8 91.5 232.5 298.2 486.6 566.8 353.9 452.8 337.3 273.9 575.3 442.1 547.6 334.8 373.6 554.3 165.6 164.2 184.3 463.9 313.6 292.0 347.3 530.2 391.6 492.9 126.0 282.5 292.4 237.0 505.3 348.9 734.7 617.0 179.6 300.1 399.8 2.2 13.0 6.9 19.8 82.0 24.4 74.2 28.0 27.1 22.1 70.4 34.0 32.8 1.7 28.7 105.4 92.6 33.3 28.1 15.0 15.8 16.4 19.8 15.4 16.2 17.5 15.8 17.7 17.4 15.7 18.8 31.7 12.8 33.3 1.3 46.5 217.6 101.3 170.6 74.0 3.4 90.6 140.5 9.2 87.2 63.1 29.5 0.0 224.0 40.7 48.3 80.3 93.0 15.8 43.1 24.6 51.9 20.4 140.1 0.8 112.1 651.8 84.6 20.9 28.3 21.0 66.7 29.6 89.8 132.1 1.7 0.8 57.4 120.1 46.0 121.0 21.7 76.1 37.4 113.8 0.0 41.3 20.7 20.6 0.5 3.5 119.0 41.7 45.9 38.4 130.2 63.1 87.5 52.1 3.0 19.7 50.6 53.0 124.7 151.0 74.9 203.6 131.9 40.7 27.2 80.0 99.5 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.1;thyroid gland: 116.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1839.9;Endometrial ciliated cells: 1221.7;Glandular and luminal cells: 1555.7;Intestinal goblet cells: 1471.3;Paneth cells: 2326.0;Proximal enterocytes: 3162.1;Undifferentiated cells: 1266.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 529.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 230.7;PC-3: 47.6;RPMI-8226: 40.5;SCLC-21H: 58.0;T-47d: 105.4" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Region enhanced" "Detected in many" "midbrain: 9.7" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA014361: AB_2668982" "unprognostic (1.84e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (1.42e-1)" "prognostic favorable (3.39e-5)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (6.72e-2)" 0.7 0.2 0.2 7.8 0.3 0.2 26.7 4.2 0.3 12.3 37.6 263.1 54.4 7.5 1.4 1.3 29.6 2.2 0.1 1.1 1.2 46.5 40.4 10.7 0.2 1.3 1.9 0.5 96.6 1.5 27.7 1.0 0.6 58.3 17.5 0.4 72.9 8.3 0.1 9.6 169.5 0.8 0.5 0.2 1.4 0.7 0.9 1.0 116.3 0.0 1.2 1.5 0.2 0.2 2.5 3.6 0.0 0.4 0.0 0.0 17.8 0.0 0.0 0.0 0.0 4.2 35.7 0.0 9.9 0.0 0.0 1.0 0.4 0.0 0.0 0.1 4.9 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 230.7 0.4 1.2 2.1 9.1 47.6 0.1 0.0 40.5 2.1 0.2 58.0 0.7 0.0 33.6 0.0 0.2 105.4 0.0 0.2 0.2 0.6 0.9 0.1 0.2 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 4.2 0.3 1.1 1.2 1.3 1.9 0.6 0.5 0.9 0.2 1.6 38.5 37.8 0.0 13.2 0.1 60.3 43.7 0.0 0.7 289.9 182.5 0.6 287.4 86.3 126.9 4.2 63.9 5.1 1839.9 9.8 297.5 0.0 1221.7 130.5 10.3 606.1 5.3 0.0 19.1 17.7 4.1 16.8 1555.7 28.0 1.5 0.4 40.5 5.1 0.0 0.0 1471.3 116.0 0.3 0.0 0.3 2.5 9.9 10.6 0.0 2.0 11.8 0.0 0.0 0.0 36.7 2326.0 0.0 4.4 433.2 3162.1 58.6 498.4 10.6 0.0 0.0 20.3 0.1 0.3 2.7 0.0 72.4 17.5 0.0 1266.0 607.3 CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 305.0;urinary bladder: 303.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 3149.1;Glandular and luminal cells: 2298.8;Paneth cells: 2081.0;Prostatic glandular cells: 2184.8;Urothelial cells: 8033.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 358.1;BEWO: 395.0;CAPAN-2: 761.4;MCF7: 400.2;OE19: 402.0;PC-3: 495.0;RT4: 340.2;SK-BR-3: 636.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" 2.6 0.4 0.1 23.0 0.0 0.2 69.0 0.8 0.3 61.2 4.8 256.3 126.9 26.7 24.4 305.0 75.8 48.9 0.4 0.2 0.0 116.2 4.8 64.0 1.0 0.4 1.5 1.2 116.2 51.9 13.1 36.3 0.3 82.2 123.3 0.3 204.6 39.1 0.5 180.8 190.6 7.3 0.0 0.7 13.3 0.6 0.2 10.7 111.7 0.3 37.5 303.5 105.7 0.0 358.1 4.4 0.0 1.5 0.0 0.4 395.0 3.3 0.2 0.3 0.4 184.9 761.4 0.6 28.0 0.1 2.6 193.3 0.0 0.5 0.4 0.7 0.4 0.2 20.3 127.0 0.1 0.1 0.9 0.0 1.9 0.1 0.4 0.3 0.0 0.2 0.3 0.7 0.0 400.2 0.7 1.9 0.7 402.0 495.0 0.5 6.9 7.6 92.4 340.2 79.5 1.7 0.4 636.8 0.8 21.6 250.9 0.9 0.5 0.9 13.7 3.1 3.5 0.9 0.7 0.7 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.2 0.0 0.4 1.5 0.3 0.0 0.2 0.0 5.1 275.7 230.2 0.0 12.2 16.2 3149.1 641.6 31.3 0.4 1255.2 548.4 0.8 287.4 954.3 218.8 0.0 771.7 18.7 1985.0 13.7 1026.1 0.0 1201.7 231.0 41.3 675.5 0.0 0.2 447.1 739.7 27.0 94.8 2298.8 27.3 0.2 0.4 0.5 76.3 0.0 0.1 1266.9 905.3 0.6 8.6 0.0 2.5 29.3 14.2 0.0 15.6 0.8 0.0 0.0 0.0 950.2 2081.0 0.0 2.5 2184.8 1906.1 21.6 635.6 0.0 0.0 0.1 68.2 0.0 0.2 1068.1 54.0 956.1 40.7 0.1 965.1 8033.4 CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1391.1;Pancreatic endocrine cells: 822.1;Paneth cells: 1276.4;Proximal enterocytes: 1390.9;Urothelial cells: 975.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 84.1;CACO-2: 90.2;CAPAN-2: 173.2;HaCaT: 364.9;MCF7: 129.8;OE19: 139.6;SK-BR-3: 150.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" 6.7 8.0 0.4 17.6 0.4 0.2 31.2 0.5 0.6 47.3 0.4 341.0 146.7 4.8 43.9 341.3 41.3 27.4 2.7 0.4 0.4 123.8 40.2 61.8 0.8 0.6 0.5 1.5 108.5 49.0 31.1 14.2 0.6 44.5 128.6 1.1 169.2 30.0 1.5 13.1 248.9 6.2 0.5 5.7 5.2 1.9 0.6 2.4 76.7 0.0 21.2 40.5 96.3 0.9 10.8 1.1 0.2 0.3 0.0 0.6 84.1 0.3 0.3 0.0 0.0 90.2 173.2 0.1 3.2 0.4 0.4 364.9 0.1 11.2 0.0 0.1 1.9 0.1 2.4 0.0 6.5 0.1 0.8 1.5 17.3 0.0 0.6 0.0 8.1 0.1 1.0 0.3 0.1 129.8 0.1 1.2 0.6 139.6 3.4 0.2 0.0 2.5 0.1 0.0 20.4 0.4 1.1 150.2 0.0 6.6 55.0 1.3 16.8 0.2 0.6 0.7 0.2 0.1 0.3 0.1 1.2 0.0 0.3 0.0 0.3 0.0 0.5 0.8 1.3 0.1 0.3 0.8 0.4 0.9 0.9 1.7 0.0 0.7 0.0 0.0 0.3 0.5 0.4 0.4 0.5 0.6 0.4 0.4 0.6 0.5 0.6 0.5 0.6 0.9 4.4 112.2 55.6 0.0 7.4 2.0 295.4 316.3 66.6 0.7 200.4 102.4 0.6 240.2 550.3 321.8 8.4 281.3 3.1 1391.1 39.2 787.5 0.1 210.1 26.6 9.0 326.8 4.0 0.0 790.0 342.7 5.2 15.3 225.5 5.7 0.1 3.6 41.2 33.7 0.0 0.0 741.7 362.2 4.1 6.4 0.2 1.2 11.0 24.9 1.9 11.0 1.6 0.0 0.0 0.0 822.1 1276.4 0.0 0.5 406.5 1390.9 78.6 498.5 6.7 0.0 0.2 38.6 0.4 3.5 366.1 2.6 588.9 10.2 1.0 691.9 975.8 CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 420.3" "Cell type enhanced" "Detected in some" "Adipocytes: 76.3;Endothelial cells: 27.9;Fibroblasts: 126.4;Hepatic stellate cells: 57.5;Leydig cells: 30.1;Microglial cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 297.9;ASC TERT1: 591.9;U-2197: 120.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" NA NA 6540000000 25000000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" 420.3 51.0 44.4 9.3 46.4 1.7 214.8 45.5 66.6 89.4 50.9 83.9 31.6 60.4 17.1 49.9 41.1 35.6 259.9 43.0 42.9 131.4 29.0 201.2 33.1 51.3 56.1 26.0 14.6 14.3 27.7 142.8 48.0 33.5 37.4 0.7 49.8 19.1 74.8 149.7 78.2 25.5 44.8 264.5 43.5 113.2 50.7 10.1 88.4 68.0 8.2 100.9 74.9 43.0 0.0 0.0 0.1 0.2 297.9 591.9 0.0 40.1 62.9 1.2 6.2 0.0 0.0 0.1 0.1 3.1 0.0 0.1 0.0 0.1 0.1 0.3 0.9 0.6 0.1 0.1 0.5 0.1 0.7 47.5 0.1 0.3 0.1 0.4 0.5 0.3 0.0 1.7 0.5 0.2 0.0 2.2 0.0 0.0 0.6 0.0 0.1 2.2 0.0 0.0 0.3 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 4.5 0.2 120.6 0.1 1.0 1.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.4 46.4 45.5 66.6 43.0 42.9 51.3 56.1 48.0 44.8 50.7 43.0 76.3 0.0 0.0 1.6 0.3 3.4 0.0 0.0 1.8 0.0 0.7 0.3 0.8 1.5 0.0 0.0 0.0 0.0 0.5 0.0 3.9 0.0 4.0 0.3 16.9 27.9 0.0 2.7 0.8 0.2 0.0 126.4 3.1 0.3 0.0 0.0 57.5 0.3 0.9 0.0 0.6 0.0 0.0 1.2 9.5 19.5 30.1 2.2 3.6 69.3 0.7 0.4 0.0 1.5 0.7 0.1 0.0 6.4 0.5 0.0 0.0 0.0 0.0 0.3 0.0 1.0 12.3 0.0 0.0 0.7 3.8 0.1 0.7 0.4 0.0 0.0 CLIC1 "CLCNL1, G6, NCC27, p64CLCP" ENSG00000213719 "Chloride intracellular channel 1" O00299 6 31730581-31739763 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020825, CAB040557" Enhanced Supported Cytosol NA NA 22000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB020825: , CAB040557: " "unprognostic (7.26e-2)" "unprognostic (9.32e-2)" "unprognostic (2.78e-3)" "unprognostic (7.29e-2)" "unprognostic (6.93e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (8.90e-7)" "unprognostic (2.58e-2)" "unprognostic (8.51e-2)" "unprognostic (8.71e-3)" "unprognostic (1.19e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (8.11e-5)" "unprognostic (4.51e-2)" "unprognostic (2.89e-1)" "unprognostic (1.35e-2)" "unprognostic (7.31e-2)" 292.8 156.5 6.9 43.4 6.8 64.0 256.7 7.1 11.0 222.2 8.7 291.6 37.0 197.9 20.9 395.9 190.5 43.7 183.7 6.7 10.2 318.5 102.6 330.4 44.1 9.4 7.7 149.8 148.1 20.1 111.5 45.5 8.9 217.0 64.0 2.6 251.3 22.3 47.3 324.8 231.6 32.7 8.9 332.6 247.8 41.0 9.6 35.2 180.8 11.1 58.1 257.7 246.8 8.9 119.5 54.1 87.0 45.6 56.6 118.6 43.3 52.8 105.4 92.6 77.9 125.2 87.2 48.7 73.6 186.0 116.9 70.2 65.8 154.9 124.4 38.9 34.4 93.0 43.4 109.3 73.0 164.3 125.9 74.3 80.5 157.0 148.4 101.7 157.9 44.6 109.4 149.5 181.0 79.2 77.2 213.2 7.7 128.9 78.4 13.5 47.5 115.3 210.2 73.0 16.5 19.5 43.1 49.1 71.5 60.4 33.7 228.3 105.0 128.6 91.2 39.0 166.8 48.3 98.3 66.0 62.4 122.0 136.6 244.3 179.4 239.3 165.6 194.3 135.8 186.1 98.0 155.5 143.8 150.3 30.5 92.3 341.1 176.3 174.3 80.5 149.2 414.2 6.9 6.8 7.1 11.0 6.7 10.2 9.4 7.7 8.9 8.9 9.6 8.9 514.8 70.5 67.0 0.7 382.5 960.8 589.1 869.7 331.2 0.4 274.3 300.5 18.6 296.0 457.7 237.3 0.0 545.5 472.2 730.7 602.6 1096.2 31.8 271.1 212.7 490.1 381.4 208.6 0.0 1008.9 912.5 296.6 370.5 301.3 554.1 431.2 300.9 54.2 1047.6 0.0 0.0 665.6 516.8 533.7 1529.8 17.3 233.9 685.7 524.7 13.1 426.4 86.8 706.5 0.5 0.0 1470.4 997.1 188.1 420.2 851.1 707.7 572.1 473.6 6.9 203.8 136.1 554.0 28.7 16.2 464.1 928.0 572.7 522.2 283.3 675.0 1005.9 CLIP1 "CLIP, CLIP-170, CLIP170, CYLN1, RSN" ENSG00000130779 "CAP-Gly domain containing linker protein 1" P30622 12 122271432-122422669 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 169.1" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 479.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004399, HPA026678" Approved Supported "Microtubule ends,Cytosol" NA NA 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Microtubule ends, Cytosol" "CAB004399: AB_671001, HPA026678: AB_1846954" "unprognostic (1.18e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (4.91e-2)" "unprognostic (6.28e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (4.73e-2)" "unprognostic (2.51e-1)" "unprognostic (7.62e-2)" "unprognostic (2.31e-2)" "unprognostic (8.97e-2)" "unprognostic (3.26e-2)" "unprognostic (5.50e-2)" "unprognostic (2.63e-1)" "unprognostic (3.37e-1)" "unprognostic (2.52e-3)" 29.6 36.7 22.5 27.8 23.5 18.0 23.2 63.0 24.4 22.8 18.3 34.1 16.9 26.2 18.0 70.8 17.0 22.3 43.1 24.4 24.0 29.7 46.2 28.1 18.4 19.0 22.5 13.1 26.8 90.1 16.4 38.9 17.7 32.5 20.6 26.9 25.2 44.4 165.4 41.3 19.7 42.4 15.7 17.3 19.6 24.8 23.3 13.9 69.5 169.1 25.2 48.3 29.8 24.3 54.2 63.5 46.0 39.1 34.8 51.7 79.4 76.3 69.2 49.2 30.0 31.7 24.4 24.2 49.8 95.7 66.9 65.6 29.7 31.2 57.9 95.0 17.0 7.7 40.2 36.3 68.6 27.8 41.5 32.1 103.3 57.0 87.6 70.3 49.2 20.2 29.4 15.0 47.7 34.6 17.4 8.7 16.7 25.7 53.2 14.7 31.5 11.6 45.5 61.9 16.1 10.7 162.9 39.5 64.0 44.9 31.4 15.9 98.2 36.8 40.1 84.3 49.3 17.0 14.4 14.1 63.0 14.0 25.6 3.3 6.5 4.0 6.6 10.6 5.1 4.9 6.1 5.9 5.6 3.0 4.5 3.2 17.1 4.7 9.4 3.2 6.3 4.1 22.5 23.5 63.0 24.4 24.4 24.0 19.0 22.5 17.7 15.7 23.3 24.3 50.2 134.6 129.9 116.2 32.4 67.2 162.6 42.4 23.9 69.6 50.0 30.1 142.2 50.1 106.5 44.1 43.8 129.7 34.5 38.0 7.9 69.0 156.9 101.2 53.1 57.3 13.9 11.3 115.3 65.5 32.9 69.1 26.0 115.0 72.7 41.3 46.4 48.3 38.3 132.9 107.7 22.3 42.7 41.8 48.5 82.9 35.8 57.0 55.2 45.0 54.2 34.8 46.4 45.2 40.7 95.6 28.5 62.1 33.0 134.4 26.4 13.2 146.5 41.8 72.3 114.6 68.4 22.0 27.4 40.3 143.3 479.4 48.5 39.6 23.0 223.9 CLSTN1 "CDHR12, CSTN1, KIAA0911" ENSG00000171603 "Calsyntenin 1" O94985 1 9728926-9823984 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 437.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012412, HPA077705" Enhanced NA NA 86000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012412: AB_1846981, HPA077705: " "unprognostic (4.63e-2)" "unprognostic (2.89e-1)" "unprognostic (9.76e-2)" "unprognostic (1.43e-1)" "unprognostic (9.79e-2)" "unprognostic (1.63e-1)" "unprognostic (2.44e-3)" "unprognostic (3.07e-2)" "unprognostic (2.54e-1)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "prognostic favorable (4.10e-7)" "unprognostic (1.12e-1)" "unprognostic (2.65e-1)" "unprognostic (4.05e-2)" "unprognostic (4.72e-2)" 28.1 27.4 49.7 23.1 65.8 10.8 31.7 29.5 137.5 61.2 80.6 59.5 29.2 85.4 21.4 51.4 69.8 48.1 35.9 79.6 15.5 41.3 6.1 29.6 33.5 24.7 18.4 60.2 65.7 36.2 48.4 35.7 32.8 61.8 38.2 110.8 79.0 45.7 23.1 83.5 41.1 49.4 7.0 28.3 31.0 15.0 23.5 35.0 40.0 28.9 27.1 38.0 59.9 45.9 120.9 55.4 52.5 64.8 71.1 50.1 35.0 80.5 71.4 82.0 70.2 32.1 235.0 90.5 203.1 95.2 52.6 157.7 41.2 245.6 32.1 114.2 74.6 27.3 53.0 39.6 116.1 46.3 41.4 58.0 156.5 105.9 50.0 78.6 113.9 52.7 13.1 52.6 35.8 47.2 53.2 26.6 37.9 53.1 59.7 80.6 21.4 42.9 73.1 20.9 91.4 53.7 94.8 160.1 79.1 22.1 34.7 73.9 155.0 89.3 80.5 56.6 109.9 75.6 75.4 124.3 72.2 79.6 95.7 6.2 0.6 2.3 3.0 0.8 1.5 0.8 1.9 2.3 1.4 1.0 1.3 1.2 0.2 0.4 0.9 0.8 1.6 1.5 49.7 65.8 29.5 137.5 79.6 15.5 24.7 18.4 32.8 7.0 23.5 45.9 40.2 28.9 15.7 63.6 23.7 43.8 61.0 73.7 84.2 205.1 53.3 47.0 14.7 55.8 44.6 51.5 437.9 34.1 35.0 221.1 1.9 29.2 4.5 44.6 47.0 36.0 30.7 17.9 150.9 38.8 14.3 40.6 29.6 52.2 11.4 54.0 35.3 2.2 28.8 180.0 138.1 96.5 14.2 24.2 13.3 5.6 46.3 21.3 32.0 46.9 21.0 160.9 28.8 90.0 56.0 59.7 66.9 50.4 31.2 42.4 54.9 27.9 68.3 165.6 85.5 39.5 31.4 24.6 37.5 44.5 26.1 19.2 33.8 47.2 59.6 42.7 CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619689-59696956 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Vesicles,Endosomes,Lysosomes,Mitotic spindle,Cytosol" Yes No 14000000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "Mitotic spindle, Cytosol" "CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: AB_2683924" "unprognostic (1.56e-1)" "prognostic unfavorable (7.35e-4)" "prognostic favorable (7.65e-4)" "unprognostic (1.03e-1)" "unprognostic (2.62e-1)" "unprognostic (5.23e-3)" "prognostic unfavorable (5.54e-4)" "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.02e-4)" 105.4 95.2 42.1 89.7 54.9 96.3 81.6 67.3 103.9 92.3 36.7 121.7 74.1 83.1 126.4 82.1 67.8 88.9 90.7 60.7 65.1 125.5 117.7 82.1 75.5 95.5 52.4 73.2 56.8 186.8 51.6 139.6 95.2 97.8 128.3 163.6 68.6 104.2 88.4 81.3 73.3 121.0 43.8 78.8 91.2 71.3 68.2 76.0 114.1 83.9 86.8 101.1 51.6 55.0 293.3 426.1 207.6 207.0 345.8 280.5 240.0 305.7 321.7 268.2 278.9 264.7 175.2 200.6 340.1 436.4 296.9 186.2 313.6 255.1 356.2 214.4 166.8 328.2 248.8 414.0 262.3 228.5 182.3 266.9 154.6 408.0 262.3 211.4 302.0 99.9 334.4 280.4 429.1 511.1 135.6 65.1 179.6 263.3 248.2 118.7 343.6 244.9 297.5 404.1 184.1 216.7 188.3 122.9 180.4 270.5 290.3 142.3 385.6 492.4 287.9 237.0 317.8 213.3 320.3 181.4 357.7 151.6 305.3 16.6 33.1 21.3 17.5 36.3 21.7 13.7 16.1 19.2 36.5 12.9 13.4 15.0 19.9 18.9 32.5 22.8 22.1 23.3 42.1 54.9 67.3 103.9 60.7 65.1 95.5 52.4 95.2 43.8 68.2 55.0 62.6 99.3 107.9 80.3 46.3 63.9 44.4 75.6 28.5 91.9 58.5 34.7 77.9 71.4 103.3 77.3 60.5 109.1 60.7 184.0 27.4 76.2 23.3 95.5 95.6 79.7 120.6 115.9 137.7 97.7 47.7 84.5 99.4 106.1 68.4 75.5 120.7 185.4 182.5 85.8 135.9 120.7 77.3 195.0 93.2 77.2 74.0 128.3 53.4 79.6 102.8 53.9 38.1 73.4 124.2 106.2 76.1 93.6 83.0 86.3 102.7 132.4 128.0 65.2 78.9 66.0 82.8 52.7 38.0 60.5 79.3 107.9 45.9 81.3 127.8 91.6 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Cone photoreceptor cells: 14.6;Early spermatids: 19.3;Late spermatids: 17.0;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.5;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Cell line enhanced" "Detected in many" "HMC-1: 64.8;K-562: 31.8" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 6.8 16.0 5.4 0.8 6.1 15.6 4.8 6.2 6.5 5.0 5.0 2.4 0.5 3.1 1.6 3.6 3.8 1.2 14.8 5.2 7.8 3.2 6.5 3.0 0.7 7.4 8.6 3.6 2.5 2.1 13.4 1.5 8.5 5.2 1.0 2.0 3.9 0.8 187.4 4.1 1.8 1.7 5.7 3.5 2.8 47.2 9.1 3.9 8.0 61.3 0.5 2.8 3.7 6.9 4.5 4.6 3.0 4.9 10.8 5.9 1.4 3.1 3.3 4.2 6.3 1.7 1.4 1.9 0.4 7.0 3.3 1.5 4.7 8.5 3.5 0.3 4.6 0.2 4.4 5.3 5.5 6.5 64.8 25.0 7.0 7.8 10.9 12.5 2.7 2.4 31.8 1.7 10.0 3.6 0.6 22.4 3.8 18.1 2.8 2.4 24.2 0.1 3.4 1.8 6.9 1.2 6.6 4.1 0.4 3.6 8.9 27.1 0.8 7.6 15.5 4.2 5.2 3.1 8.4 0.8 4.5 17.4 1.6 0.0 2.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.4 5.4 6.1 6.2 6.5 5.2 7.8 7.4 8.6 8.5 5.7 9.1 6.9 1.4 3.2 0.5 9.4 0.1 0.6 0.5 1.0 1.2 2.4 0.7 0.3 11.3 1.5 1.8 0.0 14.6 0.4 0.2 1.2 0.0 0.8 19.3 1.2 1.9 0.9 0.0 0.8 4.5 0.0 0.2 1.4 1.5 1.4 0.0 3.5 1.1 2.4 0.3 0.0 8.9 1.3 6.1 1.0 0.7 17.0 2.5 0.5 0.0 4.7 1.3 1.5 0.0 12.5 12.5 1.2 0.8 4.1 0.1 1.3 0.2 1.3 1.0 2.0 0.0 2.6 4.5 14.5 4.7 1.0 0.9 1.1 0.1 6.2 0.9 0.0 CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Group enriched" "Detected in all" 4 "Cholangiocytes: 2586.5;Collecting duct cells: 3525.7;Hepatocytes: 4230.2;Muller glia cells: 8522.6" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cell line enhanced" "Detected in all" "HeLa: 3644.3;SK-BR-3: 3500.4;T-47d: 2562.4;U-2 OS: 2225.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" 1438.7 3809.7 6730.2 897.0 6536.5 53.2 1423.8 6992.3 8050.5 1389.4 6057.7 1407.9 323.9 1152.5 9148.8 768.6 3543.7 2863.5 617.7 6660.5 8149.9 1170.5 9779.1 827.8 2309.4 10230.8 8450.9 756.7 2246.3 1689.2 827.2 131.2 8001.8 986.4 276.1 3274.6 1453.0 5466.4 114.1 281.9 662.7 1439.9 8813.6 295.4 1081.6 2709.4 7385.0 388.1 2406.8 267.7 2343.1 1777.4 741.0 9752.3 13.0 1673.1 73.2 86.4 401.4 546.1 230.7 297.8 584.8 77.3 40.1 323.4 265.5 6.6 1159.9 267.1 926.6 561.2 318.4 48.1 50.3 1268.7 306.4 741.8 3644.3 403.7 348.8 19.2 1891.2 923.4 189.1 334.0 95.5 719.5 1028.1 10.6 10.1 842.2 27.5 288.4 5.7 56.5 603.3 505.3 197.6 6.5 276.1 236.3 763.0 1220.2 66.7 41.7 412.3 3500.4 18.1 349.1 2562.4 10.3 153.2 24.0 2225.3 131.8 101.9 108.1 419.0 16.1 1808.8 122.4 10.3 767.1 18.4 8.9 19.8 6.2 7.4 0.7 23.1 21.3 6.2 1.6 2.8 7.0 79.8 9.3 1.1 11.8 6.5 1073.6 6730.2 6536.5 6992.3 8050.5 6660.5 8149.9 10230.8 8450.9 8001.8 8813.6 7385.0 9752.3 255.3 32.1 91.8 720.5 16.1 81.3 944.6 134.1 118.9 74.3 475.3 480.4 86.1 2586.5 514.0 3525.7 77.2 116.3 15.2 23.6 41.1 488.3 311.3 196.9 31.1 442.0 9.5 92.4 73.4 620.7 22.7 614.8 226.8 185.6 803.0 31.4 1037.7 4230.2 12.6 30.3 81.0 30.9 28.5 180.5 88.9 789.3 114.3 244.6 206.3 69.3 25.1 8522.6 11.3 61.3 54.3 174.8 15.0 57.2 11.6 200.5 9.9 459.2 709.1 221.4 13.1 334.4 157.7 189.8 20.3 58.8 55.3 85.6 58.7 288.9 49.3 353.7 CNBD1 FLJ35802 ENSG00000176571 "Cyclic nucleotide binding domain containing 1" Q8NA66 8 86866415-87615219 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 6.6" "Group enriched" "Detected in some" 33 "Early spermatids: 155.4;Late spermatids: 92.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 4.4;U-266/70: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025037, HPA027469, HPA027786" Uncertain "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA025037: AB_10794318, HPA027469: AB_10599492, HPA027786: AB_10600231" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 155.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 92.3 1.2 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CNBP "CNBP1, DM2, RNF163, ZCCHC22, ZNF9" ENSG00000169714 "CCHC-type zinc finger nucleic acid binding protein" P62633 3 129167827-129183922 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063097 Approved Nucleoplasm,Cytosol NA NA 160000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA063097: AB_2684939" "unprognostic (1.74e-1)" "unprognostic (3.11e-2)" "unprognostic (4.84e-1)" "unprognostic (3.35e-2)" "unprognostic (6.28e-2)" "unprognostic (7.38e-2)" "unprognostic (7.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (6.39e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (4.72e-3)" "unprognostic (4.62e-3)" "unprognostic (1.89e-1)" "unprognostic (2.03e-1)" "unprognostic (2.51e-1)" "unprognostic (1.58e-1)" 292.7 308.2 175.2 181.1 184.0 254.1 274.6 198.6 211.3 295.9 175.7 314.1 198.5 285.8 197.6 264.6 275.7 195.1 487.2 170.6 184.3 231.6 433.7 258.3 251.0 182.7 175.1 385.8 307.4 277.9 169.5 214.3 187.1 256.6 219.0 231.8 250.8 282.4 1207.6 288.0 199.2 234.9 195.6 200.7 262.1 131.2 181.9 254.2 261.8 797.9 250.7 317.5 269.2 211.7 452.7 266.4 369.9 294.6 355.2 303.9 294.9 344.2 535.7 362.2 412.4 389.2 305.7 589.8 292.2 318.1 269.6 328.3 484.3 396.4 484.6 404.5 357.9 569.2 251.7 420.2 355.7 622.4 314.5 295.5 449.2 254.8 897.8 247.6 324.1 328.1 437.6 391.9 384.0 538.9 578.6 454.1 452.7 399.7 439.1 502.4 343.4 707.7 379.1 425.4 501.2 402.8 271.5 263.0 766.3 214.4 305.6 421.3 347.9 268.4 266.2 374.1 353.7 367.3 365.4 932.3 277.3 419.2 362.4 1077.7 810.5 930.9 551.8 596.8 699.0 691.0 658.8 595.3 552.8 603.8 700.3 610.5 1102.3 601.1 485.5 320.4 704.3 2029.8 175.2 184.0 198.6 211.3 170.6 184.3 182.7 175.1 187.1 195.6 181.9 211.7 253.7 259.6 263.9 27.1 292.8 524.7 417.0 262.9 259.6 153.7 177.5 272.5 608.0 141.5 235.1 79.1 33.3 252.3 188.1 143.9 373.7 226.9 36.0 141.4 195.1 267.5 171.3 246.5 28.2 290.7 396.6 309.4 142.8 172.8 314.5 173.0 167.0 138.5 246.5 92.5 33.7 178.6 140.4 194.4 463.0 42.9 316.0 232.4 318.4 35.6 392.7 350.3 236.9 32.6 42.8 230.1 158.0 319.7 311.7 405.1 196.5 237.4 164.8 153.8 263.0 343.6 571.0 305.2 271.5 286.5 586.7 291.7 304.2 277.7 213.6 376.2 CNKSR1 "CNK, CNK1, KSR" ENSG00000142675 "Connector enhancer of kinase suppressor of Ras 1" Q969H4 1 26177484-26189884 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 18.6;BEWO: 16.0;CAPAN-2: 29.1;HaCaT: 20.3;hTCEpi: 17.2;OE19: 15.9;SK-BR-3: 20.8;T-47d: 16.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA030847 Uncertain Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA030847: AB_10601100" "unprognostic (2.73e-3)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (5.07e-2)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (1.61e-2)" "unprognostic (5.26e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-1)" "unprognostic (2.49e-3)" "unprognostic (1.69e-3)" "unprognostic (1.90e-2)" "unprognostic (3.27e-2)" "unprognostic (2.91e-1)" "prognostic favorable (5.91e-4)" 0.7 0.1 3.6 2.6 4.1 0.3 6.0 5.3 4.7 6.6 2.2 9.4 11.9 2.5 8.2 18.7 8.2 3.6 1.4 3.6 3.7 9.5 1.6 7.3 1.4 4.0 3.6 3.2 13.4 11.7 9.6 4.7 3.8 10.3 7.4 0.9 15.6 6.6 57.2 16.6 11.4 0.7 3.2 2.4 10.5 2.4 3.8 1.1 16.7 14.3 2.9 5.5 9.0 4.9 18.6 0.0 0.3 0.2 0.3 0.0 16.0 0.3 0.0 0.2 0.0 2.9 29.1 2.0 9.1 0.0 0.2 20.3 0.5 13.0 0.4 0.0 0.9 0.4 7.4 9.2 0.1 0.2 0.3 0.0 17.2 0.0 5.0 0.0 0.0 0.6 2.2 0.1 0.0 8.4 0.2 1.5 7.7 15.9 1.7 0.2 0.2 0.0 1.9 10.7 3.5 0.9 0.1 20.8 0.3 6.9 16.7 0.0 0.0 0.0 2.4 1.0 0.2 5.8 1.1 0.7 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.8 0.1 3.6 4.1 5.3 4.7 3.6 3.7 4.0 3.6 3.8 3.2 3.8 4.9 1.6 16.0 7.2 3.6 3.1 14.7 16.9 36.6 17.6 2.8 22.9 20.2 1.1 17.2 21.2 35.0 2.1 34.2 0.5 26.7 1.9 12.3 1.1 15.9 2.8 1.9 18.6 0.0 3.3 12.4 13.7 1.3 34.7 25.9 0.0 1.8 0.7 0.2 2.8 0.0 3.7 20.0 28.5 0.0 1.2 0.8 1.2 0.8 1.8 0.0 1.4 0.7 0.0 0.5 5.1 25.0 29.9 0.7 14.3 15.7 28.4 0.5 33.1 2.9 0.0 3.6 3.3 2.4 4.2 20.2 11.4 32.4 1.1 0.1 20.0 26.6 CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 1872.4;intestine: 2657.3;smooth muscle: 2207.8" "Group enriched" "Detected in many" 5 "Breast myoepithelial cells: 191.0;Early spermatids: 335.0;Late spermatids: 554.6;Peritubular cells: 221.2;Smooth muscle cells: 180.9" "Cancer enhanced" "Detected in all" "prostate cancer: 142.1;stomach cancer: 103.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 91.5;BJ hTERT+: 34.9;BJ hTERT+ SV40 Large T+: 48.0;BJ hTERT+ SV40 Large T+ RasG12V: 64.6;HBF TERT88: 71.2;K-562: 35.8;SuSa: 72.5;U-2 OS: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Actin filaments" "CAB000007: AB_2082148, HPA014263: AB_1847039" "unprognostic (4.98e-3)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "unprognostic (1.95e-1)" "unprognostic (2.47e-1)" "unprognostic (4.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (5.43e-6)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.78e-3)" "unprognostic (6.11e-3)" 115.6 58.4 6.4 160.6 8.3 0.0 89.7 5.7 14.2 366.9 7.5 2657.3 136.3 1872.4 177.0 677.5 655.6 234.3 274.1 6.8 8.5 42.9 10.6 98.7 7.3 6.1 6.8 114.1 24.2 3.0 9.0 28.4 6.3 676.0 326.4 0.7 61.6 1585.7 21.8 57.8 431.3 2207.8 6.1 22.1 673.7 91.4 7.5 2.6 38.5 11.7 0.9 1386.6 305.7 6.3 0.1 1.3 5.9 1.0 0.6 0.2 3.2 91.5 34.9 48.0 64.6 27.9 0.0 0.4 2.7 26.1 4.4 0.3 0.0 0.0 71.2 0.0 0.2 0.1 0.1 2.3 2.5 0.0 0.4 3.0 0.1 28.7 0.1 1.6 0.0 0.0 35.8 0.0 0.0 0.0 0.3 3.8 2.9 0.0 0.7 0.2 0.6 3.8 0.0 0.0 0.1 1.3 0.1 0.2 0.2 72.5 0.1 0.1 0.4 0.4 34.6 1.2 1.2 0.1 0.4 0.1 3.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.4 8.3 5.7 14.2 6.8 8.5 6.1 6.8 6.3 6.1 7.5 6.3 2.4 0.0 0.0 0.0 0.2 4.8 4.1 1.6 0.6 0.0 4.2 191.0 51.4 0.0 0.3 1.8 0.0 0.8 0.7 0.0 0.0 14.5 335.0 3.1 20.7 2.4 0.0 0.0 0.5 0.4 1.0 21.5 0.5 0.7 0.0 0.5 6.8 0.0 2.3 0.0 0.3 0.0 0.0 0.0 9.4 554.6 8.4 0.9 3.6 2.8 0.6 0.5 0.0 0.0 0.1 0.9 0.0 221.2 0.0 4.0 0.0 0.4 0.4 0.0 39.5 1.1 180.9 8.3 19.5 0.4 7.1 0.7 1.1 0.7 0.0 1.1 CNOT3 "KIAA0691, LENG2, NOT3, NOT3H" ENSG00000088038 "CCR4-NOT transcription complex subunit 3" O75175 19 54137749-54155681 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 213.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006408 Approved Approved Cytosol NA NA 39000 "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA006408: AB_1078543" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (1.75e-2)" "unprognostic (1.40e-1)" "unprognostic (4.86e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (9.06e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (9.30e-3)" "unprognostic (4.08e-3)" "prognostic unfavorable (2.77e-4)" "unprognostic (2.18e-1)" "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" 21.3 29.0 11.3 17.5 11.6 19.6 22.9 13.7 14.1 27.0 7.6 27.1 16.8 27.3 19.6 26.8 27.5 12.5 19.4 10.9 14.2 24.8 25.3 21.2 20.4 12.0 9.5 30.5 28.3 17.5 34.0 19.2 10.4 27.6 13.2 18.0 26.1 18.7 24.1 30.3 25.1 16.8 7.1 29.9 26.6 35.2 10.8 23.6 30.0 11.0 18.1 25.6 25.5 12.0 45.5 69.1 69.7 40.8 25.4 25.2 48.0 39.2 68.4 52.2 45.9 44.2 36.2 53.1 24.8 46.1 41.8 44.1 77.3 39.2 53.1 55.5 213.4 81.7 44.5 39.1 43.3 47.7 54.9 32.1 35.8 46.7 77.3 37.1 41.5 39.0 61.8 47.9 38.3 53.3 63.8 27.9 43.1 87.7 52.4 57.8 52.4 35.7 33.7 85.4 44.9 37.2 75.1 54.6 25.8 50.6 31.3 50.2 37.8 47.3 50.3 23.4 54.4 46.3 54.1 71.2 38.7 37.1 48.0 0.9 1.6 3.1 1.6 1.0 1.2 1.3 1.1 1.5 1.4 1.4 1.2 1.3 4.2 0.8 1.4 3.4 1.2 2.0 11.3 11.6 13.7 14.1 10.9 14.2 12.0 9.5 10.4 7.1 10.8 12.0 14.2 12.8 7.4 10.7 17.4 9.9 17.2 15.7 18.8 17.5 14.0 13.8 2.0 12.8 14.4 7.3 16.7 28.8 20.5 17.8 9.8 14.8 19.9 20.9 19.6 13.2 14.4 13.3 6.1 14.5 28.5 13.6 20.9 21.4 3.8 22.7 12.5 8.5 16.2 16.8 7.0 17.1 18.3 9.7 6.9 6.6 17.1 13.1 5.4 4.7 15.6 12.0 16.5 5.0 8.0 15.1 23.9 9.4 20.8 21.4 14.9 9.0 14.3 18.5 6.6 17.3 17.9 49.2 47.9 16.6 9.9 50.1 15.4 21.6 13.2 17.3 CNTF HCNTF ENSG00000242689 "Ciliary neurotrophic factor" P26441 11 58622665-58625733 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.9;brain: 7.7" "Cell type enhanced" "Detected in single" "Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 7.9" "Low region specificity" "Detected in all" HPA019654 Approved Approved Vesicles NA NA 69200 "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA019654: AB_1859050" "unprognostic (1.88e-1)" "unprognostic (2.64e-3)" "unprognostic (1.01e-2)" "unprognostic (4.37e-2)" "unprognostic (1.52e-1)" "unprognostic (5.91e-2)" "unprognostic (1.63e-1)" "unprognostic (9.24e-2)" "unprognostic (5.87e-2)" "unprognostic (1.63e-1)" "unprognostic (8.25e-4)" "unprognostic (5.42e-2)" "unprognostic (8.50e-2)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.50e-2)" "unprognostic (9.67e-2)" 0.9 0.5 1.2 0.6 3.0 6.9 0.7 2.9 2.4 0.2 1.2 0.6 0.9 0.2 0.9 0.6 4.7 0.5 1.6 1.1 2.0 0.6 0.8 0.6 0.5 5.8 3.6 0.2 0.5 0.4 0.4 0.4 3.9 0.3 0.8 0.8 1.1 0.3 3.2 0.9 0.7 0.4 3.4 0.4 0.4 0.6 2.2 0.7 0.6 1.8 0.4 0.4 0.3 7.7 1.3 0.5 2.1 2.2 0.6 0.2 1.1 0.9 1.4 1.0 0.7 1.9 1.8 2.8 0.7 1.4 1.1 2.4 2.3 2.5 2.0 1.9 1.3 1.4 3.1 1.0 0.3 2.2 2.5 0.6 0.8 3.2 1.0 0.4 1.0 1.9 2.2 0.6 1.3 0.5 2.1 2.1 1.3 1.0 1.0 1.3 1.4 2.0 1.2 1.6 0.9 2.6 1.4 1.5 3.7 1.5 1.8 1.6 0.7 1.5 1.1 7.9 2.6 1.4 3.3 2.3 4.0 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.0 2.9 2.4 1.1 2.0 5.8 3.6 3.9 3.4 2.2 7.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.1 CNTRL "CEP1, CEP110" ENSG00000119397 Centriolin Q7Z7A1 9 121074753-121177610 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.0;testis: 35.3" "Cell type enhanced" "Detected in many" "Early spermatids: 131.7;Spermatocytes: 385.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 81.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020468, HPA020480, HPA051583" Approved Approved "Centriolar satellite,Centrosome,Cytosol" NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centrosome, Cytosol" "Centriolar satellite" "HPA020468: AB_2670455, HPA020480: AB_2670457, HPA051583: AB_2681542" "unprognostic (4.33e-3)" "unprognostic (2.89e-3)" "unprognostic (2.09e-2)" "unprognostic (7.97e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.21e-5)" "unprognostic (1.05e-2)" "unprognostic (3.22e-3)" "unprognostic (3.74e-3)" "unprognostic (2.02e-1)" "unprognostic (1.78e-2)" "unprognostic (5.47e-2)" "unprognostic (3.60e-3)" "unprognostic (9.83e-3)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.13e-2)" 5.3 3.7 2.5 13.8 3.6 28.0 5.0 4.0 3.2 4.4 6.9 4.6 4.0 6.7 2.7 4.1 7.8 5.4 2.8 2.1 3.3 2.8 4.1 6.7 23.3 5.4 5.5 7.5 3.9 2.8 3.1 6.3 4.1 4.5 5.6 7.5 3.6 3.8 1.1 4.9 5.2 4.9 3.7 12.6 7.8 35.3 3.4 23.9 4.8 1.8 21.7 6.5 2.8 5.3 12.6 8.3 22.5 16.4 3.3 4.9 4.2 8.4 6.2 6.6 5.6 4.7 13.2 55.7 3.3 6.3 11.8 25.2 7.6 5.2 10.4 34.3 5.5 29.4 15.2 6.1 4.5 81.0 34.1 3.1 3.8 6.9 16.5 2.8 14.6 22.7 19.2 31.0 6.5 7.9 31.2 21.5 8.1 16.0 6.6 30.1 33.4 17.4 3.1 5.7 8.5 12.9 28.4 5.2 6.3 3.9 11.0 36.0 10.3 6.7 11.6 10.8 15.8 22.0 25.6 37.8 5.6 32.2 16.1 16.2 7.0 17.0 7.2 4.3 5.5 11.7 7.5 5.5 3.7 11.9 9.0 6.4 2.7 5.0 6.5 10.6 11.5 2.8 2.5 3.6 4.0 3.2 2.1 3.3 5.4 5.5 4.1 3.7 3.4 5.3 19.8 28.9 32.8 34.9 78.7 3.3 13.8 6.8 9.1 33.5 7.4 12.2 8.9 10.0 29.5 3.7 37.5 2.7 58.2 2.7 3.9 5.1 131.7 61.8 12.3 14.8 8.4 33.2 35.4 6.0 3.0 15.1 14.8 10.9 53.0 20.6 14.6 3.9 27.2 30.3 43.8 8.4 4.1 33.9 16.5 44.3 13.7 50.7 8.8 52.5 55.2 8.2 49.4 37.2 53.1 6.3 4.5 12.0 39.1 4.3 2.2 1.4 114.6 59.6 39.5 33.8 14.5 385.0 114.1 10.9 5.7 0.8 57.0 13.1 6.4 6.2 COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 20.1;retina: 9.6" "Cell type enhanced" "Detected in some" "Astrocytes: 83.9;Excitatory neurons: 99.5;Oligodendrocyte precursor cells: 557.4;Theca cells: 139.6" "Cancer enhanced" "Detected in many" "breast cancer: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 116.9;BJ: 43.2;BJ hTERT+ SV40 Large T+ RasG12V: 85.3;HBF TERT88: 48.7;HSkMC: 142.5;SuSa: 60.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058335 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 640000 "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Endoplasmic reticulum" "HPA058335: AB_2683682" "unprognostic (2.60e-3)" "unprognostic (6.61e-4)" "unprognostic (9.58e-2)" "unprognostic (5.06e-5)" "unprognostic (2.83e-1)" "unprognostic (2.85e-2)" "unprognostic (6.03e-3)" "unprognostic (2.23e-3)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (1.94e-2)" "unprognostic (3.01e-12)" "unprognostic (1.27e-2)" "unprognostic (3.53e-1)" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" 0.6 0.6 4.3 0.3 3.1 0.0 0.4 1.6 4.6 0.9 2.8 0.4 0.1 0.5 0.1 0.0 0.0 3.1 0.0 2.4 2.5 0.1 0.0 0.3 0.1 2.5 3.7 0.6 0.7 0.2 3.3 20.1 2.2 0.2 0.3 9.6 1.5 0.8 0.1 1.4 0.1 0.3 1.0 0.5 0.1 1.4 2.2 0.0 0.1 0.1 0.0 0.2 0.1 2.1 0.0 0.8 116.9 0.0 4.6 5.9 0.0 43.2 16.1 23.3 85.3 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 142.5 0.0 1.1 0.0 17.7 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 8.1 0.0 0.1 0.0 7.4 0.0 15.2 0.0 0.1 0.0 0.0 0.1 0.0 60.5 0.0 0.1 0.0 0.6 27.0 0.0 4.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.1 1.6 4.6 2.4 2.5 2.5 3.7 2.2 1.0 2.2 2.1 0.0 0.0 2.2 83.9 0.0 1.8 0.0 0.0 0.0 9.4 0.1 4.2 0.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 21.0 0.1 0.9 2.2 0.0 0.0 99.5 0.0 0.8 18.7 0.0 0.0 2.5 8.3 0.0 0.0 0.3 0.0 32.9 0.0 0.0 0.0 1.3 4.0 1.2 0.2 10.6 29.0 0.0 29.8 0.0 557.4 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.9 2.6 0.5 0.8 0.0 1.1 0.3 0.2 139.6 0.0 0.0 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 19.1;pituitary gland: 9.2;retina: 5.6;stomach 1: 12.5" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Enteroendocrine cells: 43.9;Late spermatids: 9.7;Muller glia cells: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 156.3;HAP1: 98.9;HEK 293: 36.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" No NA 1400000 "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Nucleoplasm "CAB002214: AB_563666, HPA055753: AB_2682908" "unprognostic (7.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.88e-2)" "unprognostic (3.08e-2)" "unprognostic (8.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.31e-4)" "unprognostic (2.64e-1)" "unprognostic (3.44e-3)" "unprognostic (1.89e-1)" "unprognostic (2.93e-1)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.1 0.0 0.2 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.2 0.2 1.3 0.0 0.0 9.2 0.3 0.3 1.0 0.3 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.5 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.7 0.0 0.0 0.0 98.9 0.0 0.0 0.0 36.3 0.2 0.0 5.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 2.9 0.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 11.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.0 0.6 5.7 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 15.4 0.3 0.1 0.2 43.9 0.0 0.2 0.0 0.3 0.5 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 9.7 0.9 0.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 1.7 0.0 0.9 0.3 0.6 1.1 0.0 0.0 0.8 0.1 0.1 1.7 0.1 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 52.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Bipolar cells: 62.1;Cone photoreceptor cells: 398.2;Muller glia cells: 143.1;Oligodendrocyte precursor cells: 84.9" "Group enriched" "Detected in some" 6 "lung cancer: 1.7;renal cancer: 3.0;thyroid cancer: 5.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cell line enhanced" "Detected in some" "HeLa: 18.8;hTERT-RPE1: 14.5;Karpas-707: 9.9;RPTEC TERT1: 11.0;U-266/70: 9.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA042064: AB_10794410" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-6)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (1.84e-2)" "unprognostic (7.07e-3)" "unprognostic (2.30e-1)" "unprognostic (9.09e-3)" "unprognostic (9.30e-2)" "unprognostic (3.02e-2)" "prognostic favorable (2.51e-7)" "unprognostic (1.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" 0.6 11.5 1.9 2.1 1.8 0.3 1.0 1.5 1.7 0.4 21.5 0.8 0.7 1.2 16.3 1.0 2.1 3.2 8.9 1.4 2.0 30.5 0.6 15.0 2.9 3.3 3.1 3.9 5.0 0.2 16.2 0.2 2.7 6.0 1.0 52.9 1.2 9.9 22.2 0.5 6.7 0.8 1.6 7.2 1.8 1.7 6.3 0.4 20.5 15.2 5.6 1.4 1.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.0 0.3 1.1 0.1 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 1.2 0.0 9.9 0.0 0.4 0.0 0.1 1.4 0.0 0.0 0.1 0.0 3.2 11.0 2.3 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 9.0 3.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 1.5 1.7 1.4 2.0 3.3 3.1 2.7 1.6 6.3 2.2 0.5 169.9 31.7 3.9 14.0 0.1 0.1 0.1 0.6 62.1 0.1 0.9 2.6 1.5 9.3 42.3 398.2 0.1 0.1 0.0 0.0 0.1 0.7 0.1 0.2 2.4 0.0 0.0 5.5 1.0 0.0 4.6 0.5 0.3 1.3 22.8 0.4 0.2 0.0 1.7 14.1 0.0 0.0 0.0 0.3 0.3 8.4 0.3 1.8 13.1 0.0 143.1 0.0 84.9 3.6 1.0 0.0 12.0 8.0 0.1 0.0 1.9 0.1 11.9 13.1 11.7 3.6 0.4 0.0 0.3 0.3 0.0 1.2 0.1 0.0 0.0 COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Collecting duct cells: 46.0;Cone photoreceptor cells: 56.3;Granulosa cells: 62.6;Muller glia cells: 78.6;Oligodendrocyte precursor cells: 55.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 34.3;hTERT-RPE1: 27.2;Karpas-707: 8.9;RPTEC TERT1: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" 1.0 6.9 1.3 2.1 1.1 0.1 0.7 0.9 0.9 0.5 14.2 0.9 0.9 2.0 7.2 1.1 2.1 4.4 9.2 1.0 1.3 14.0 1.6 8.3 2.8 3.1 2.2 2.0 5.5 0.6 10.2 0.3 2.6 4.5 0.8 8.4 0.7 8.3 6.9 0.3 2.4 1.6 1.5 1.9 1.2 1.3 4.4 0.9 9.9 5.7 4.5 2.9 0.9 1.3 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.1 0.6 0.0 0.7 0.0 1.7 0.0 0.7 0.1 3.1 1.1 0.2 0.0 3.4 0.0 34.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 27.2 0.0 1.1 0.0 8.9 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 14.5 5.6 0.8 0.0 2.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 2.7 0.0 0.3 6.7 5.3 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.3 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.1 0.9 0.9 1.0 1.3 3.1 2.2 2.6 1.5 4.4 1.3 2.0 73.7 24.1 3.6 11.1 0.5 0.4 0.2 0.0 29.1 0.5 1.3 3.5 8.6 6.2 46.0 56.3 0.0 1.4 0.1 1.9 0.3 0.8 0.3 1.8 5.2 1.2 0.0 2.5 3.8 0.0 8.1 1.5 0.9 0.0 62.6 2.5 0.7 0.1 0.0 10.4 0.1 2.0 0.3 1.5 4.3 25.1 0.8 0.0 12.2 0.0 78.6 0.0 55.3 3.4 4.1 0.1 27.1 14.9 0.2 0.0 3.6 0.0 8.5 0.0 16.8 8.6 0.1 0.6 0.2 0.0 0.0 1.4 0.9 0.3 0.1 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Astrocytes: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 38.9;BJ: 23.6;BJ hTERT+: 26.2;BJ hTERT+ SV40 Large T+: 14.4;HSkMC: 28.2;WM-115: 26.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" 47.4 5.0 33.2 9.9 33.2 0.1 32.3 30.6 45.9 44.9 43.6 19.3 3.7 27.3 1.9 9.0 22.8 4.1 33.5 33.3 26.4 7.9 13.4 14.2 3.2 35.2 30.2 6.3 5.2 3.0 3.5 32.8 32.3 16.6 2.0 21.1 7.3 8.9 15.3 21.7 11.7 10.3 31.0 1.7 9.9 4.7 30.2 4.5 12.7 6.0 3.9 12.6 26.4 28.4 0.0 0.0 0.5 0.0 12.4 38.9 0.0 23.6 26.2 14.4 5.7 0.0 0.0 0.0 0.2 4.4 0.3 2.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 28.2 0.6 5.2 5.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.1 0.0 0.0 0.0 11.6 5.5 0.5 0.0 0.0 0.0 0.0 1.5 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 33.2 30.6 45.9 33.3 26.4 35.2 30.2 32.3 31.0 30.2 28.4 13.7 0.0 0.0 510.3 0.0 4.2 0.1 0.2 2.2 65.1 0.3 0.9 6.4 0.0 0.1 0.0 6.2 0.1 0.3 1.3 0.0 0.2 6.9 0.4 12.0 8.1 0.0 0.0 15.6 0.0 0.2 17.5 0.5 0.4 0.0 0.0 3.9 22.9 0.6 3.3 3.4 0.0 0.0 0.0 3.2 2.1 17.4 0.4 14.2 36.5 0.1 2.6 0.0 73.9 2.5 0.3 0.1 8.2 0.0 0.3 0.2 0.1 0.9 28.3 92.1 8.5 58.0 0.3 0.3 3.2 7.1 0.1 1.9 0.9 0.0 0.3 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COX17 ENSG00000138495 "Cytochrome c oxidase copper chaperone COX17" Q14061 3 119654513-119677454 "Cancer-related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042226, HPA048158" Supported Supported Mitochondria NA NA 220000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA042226: AB_2677911, HPA048158: AB_2680292" "unprognostic (1.98e-2)" "unprognostic (3.49e-2)" "unprognostic (1.96e-2)" "unprognostic (8.29e-2)" "unprognostic (2.88e-2)" "unprognostic (6.63e-3)" "unprognostic (3.49e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-1)" "unprognostic (7.11e-3)" "unprognostic (2.12e-1)" "unprognostic (4.45e-2)" "unprognostic (1.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.65e-1)" "unprognostic (9.19e-2)" "unprognostic (2.64e-2)" 81.6 178.5 106.5 77.1 111.2 113.3 68.8 117.5 122.4 50.3 149.2 90.2 90.2 41.2 114.1 55.9 47.3 59.4 279.9 105.5 123.6 94.7 172.7 62.3 110.4 115.8 115.3 31.5 102.0 412.1 119.2 63.9 115.7 78.6 78.7 120.6 80.8 90.7 401.4 43.3 88.5 62.9 112.5 64.9 107.5 44.4 113.0 106.6 94.4 363.9 89.8 75.9 35.7 118.6 219.6 257.0 122.7 33.3 53.4 53.1 45.7 130.5 84.2 127.3 133.4 226.4 157.7 164.6 158.0 72.1 174.8 84.0 138.5 154.9 74.9 205.5 155.9 145.0 195.3 180.1 63.1 205.0 246.7 56.6 142.7 77.9 106.0 82.2 87.9 200.8 122.4 370.7 155.4 410.2 212.8 283.5 133.8 212.2 413.3 88.3 82.3 273.7 203.2 141.0 210.5 86.4 153.1 137.1 189.7 76.9 180.5 313.0 66.6 91.3 144.9 59.8 168.4 257.5 348.9 361.1 129.0 157.8 164.2 591.4 241.1 630.6 218.1 357.5 208.1 378.3 241.7 230.3 252.8 320.4 189.1 187.0 174.4 213.6 487.3 538.7 352.6 260.1 106.5 111.2 117.5 122.4 105.5 123.6 115.8 115.3 115.7 112.5 113.0 118.6 194.5 157.0 167.1 5.2 161.5 94.1 132.8 267.9 46.7 108.9 153.8 147.2 622.8 238.8 202.4 498.4 43.8 137.4 116.7 385.3 716.1 264.0 115.0 282.4 64.3 164.7 214.2 162.9 3.8 413.7 193.9 99.3 150.3 178.8 309.3 70.2 116.0 779.8 216.1 75.7 5.6 327.8 427.2 181.8 281.2 39.9 91.0 190.8 277.5 11.2 345.7 178.8 137.0 8.5 8.8 459.7 512.8 136.9 176.5 198.2 434.6 786.2 280.2 174.4 184.1 112.9 171.6 286.0 159.2 85.4 125.4 211.0 129.0 49.6 151.1 199.0 CP ENSG00000047457 Ceruloplasmin P00450 3 149162410-149221829 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 1871.4" "Cell type enhanced" "Detected in many" "Club cells: 558.1;Glandular and luminal cells: 406.0;Hepatocytes: 1687.2;Muller glia cells: 720.5;Respiratory ciliated cells: 318.4" "Cancer enhanced" "Detected in many" "liver cancer: 98.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "EFO-21: 318.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001834, CAB008591" Supported "Secreted to blood" NA NA 160000000000 440000000000 "Cluster 62: Liver - Hemostasis" "Cluster 38: EFO-21 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "CAB008591: AB_1613734, HPA001834: AB_1078502" "unprognostic (3.58e-1)" "unprognostic (4.24e-1)" "unprognostic (9.61e-2)" "unprognostic (1.80e-2)" "unprognostic (4.14e-2)" "unprognostic (1.02e-2)" "unprognostic (1.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "unprognostic (6.03e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (1.14e-7)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (2.70e-1)" 13.0 2.3 17.9 2.2 18.1 0.9 20.8 18.7 29.8 70.2 129.2 13.0 9.8 14.8 0.0 5.6 8.3 1.1 39.2 17.5 33.0 9.5 1871.4 13.4 18.9 28.1 20.3 0.8 6.5 3.9 28.6 3.4 24.9 7.9 16.4 246.5 39.9 0.9 2.6 13.0 20.8 2.4 19.2 23.1 3.0 1.5 20.1 0.5 16.1 8.3 20.0 23.9 2.3 29.0 0.2 18.8 15.6 0.0 3.3 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 318.8 0.0 29.4 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.4 32.7 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 2.5 5.4 0.0 0.0 0.0 0.4 6.7 16.2 0.0 0.2 0.3 1.0 0.1 0.4 0.0 0.4 0.0 0.2 1.7 0.2 0.2 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.1 18.7 29.8 17.5 33.0 28.1 20.3 24.9 19.2 20.1 29.0 2.3 19.2 76.6 3.3 10.6 3.3 8.3 28.6 0.6 6.9 14.0 0.6 0.6 65.8 558.1 9.2 6.2 0.1 0.3 0.1 0.0 83.4 0.9 190.5 51.0 12.6 0.0 34.7 1.5 21.4 0.2 16.3 0.0 406.0 2.5 0.1 34.6 1687.2 0.6 5.0 1.4 0.2 8.2 44.6 6.9 1.2 0.3 4.0 0.0 6.5 1.6 720.5 1.0 0.5 2.0 69.3 0.0 0.4 0.3 19.5 0.0 0.3 318.4 24.8 0.0 0.8 15.3 0.0 0.1 0.8 2.6 0.3 4.9 0.1 0.1 79.0 CRABP1 "CRABP, CRABP-I, CRABPI, RBP5" ENSG00000166426 "Cellular retinoic acid binding protein 1" P29762 15 78340353-78348225 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 544.1;thyroid gland: 173.2" "Cell type enriched" "Detected in some" 24 "Muller glia cells: 4845.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 117.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 1022.7;NTERA-2: 307.4" "Group enriched" "Detected in many" 5 "amygdala: 6.4;basal ganglia: 23.4;hypothalamus: 13.3;olfactory bulb: 12.8;pons and medulla: 7.4" "Low region specificity" "Detected in all" HPA017203 Enhanced Supported NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA017203: AB_1846512" "unprognostic (1.23e-1)" "unprognostic (3.76e-3)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (2.01e-1)" "unprognostic (4.35e-2)" "unprognostic (1.05e-1)" "unprognostic (1.35e-1)" "unprognostic (2.45e-2)" "unprognostic (9.79e-2)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (9.37e-2)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (2.69e-1)" 0.9 1.7 14.2 2.5 24.8 0.2 56.1 25.6 26.4 1.3 28.5 6.9 0.8 2.3 2.0 0.6 0.3 1.6 0.4 9.6 39.6 15.5 0.0 0.7 0.2 61.7 62.6 0.4 0.7 0.0 27.6 15.0 58.4 2.6 1.7 544.1 1.1 47.4 0.2 26.7 5.0 1.8 23.8 75.2 7.1 0.5 86.2 1.7 173.2 0.2 1.2 0.6 2.5 13.7 0.0 0.2 1022.7 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 65.3 0.9 0.0 6.3 0.0 0.3 0.0 9.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 57.9 0.4 307.4 1.0 0.8 0.0 0.0 0.0 0.0 1.5 85.5 58.0 0.0 0.2 0.1 24.8 1.4 35.9 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 24.8 25.6 26.4 9.6 39.6 61.7 62.6 58.4 23.8 86.2 13.7 1.0 0.0 0.0 0.3 0.8 9.7 0.1 0.0 0.0 31.1 112.6 199.0 0.0 0.0 0.0 0.0 33.3 1.1 2.9 1.1 70.5 0.0 0.0 0.1 0.1 4.8 0.0 0.0 0.2 0.0 0.8 11.3 0.0 0.1 0.0 4.2 0.0 0.0 1.5 10.1 1.5 0.4 0.0 0.0 5.3 0.0 0.0 0.5 192.1 0.0 0.0 4845.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.4 0.5 0.0 91.2 0.0 0.0 1.0 0.1 2.2 0.0 2.6 1.4 0.9 0.0 1.6 0.1 CRADD RAIDD ENSG00000169372 "CASP2 and RIPK1 domain containing adaptor with death domain" P78560 12 93677375-93894840 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 161.3;Early spermatids: 164.5;Inhibitory neurons: 122.3;Oligodendrocyte precursor cells: 174.4;Oligodendrocytes: 287.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005337 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Nucleoplasm "CAB005337: AB_2085481" "unprognostic (1.07e-2)" "prognostic favorable (9.06e-5)" "unprognostic (9.65e-3)" "unprognostic (5.51e-2)" "unprognostic (2.88e-1)" "unprognostic (3.10e-1)" "unprognostic (3.79e-2)" "unprognostic (8.99e-2)" "unprognostic (1.54e-1)" "unprognostic (7.89e-2)" "unprognostic (6.06e-2)" "unprognostic (3.18e-2)" "prognostic favorable (4.04e-9)" "unprognostic (2.57e-2)" "unprognostic (6.86e-2)" "unprognostic (2.08e-1)" "unprognostic (3.02e-2)" 10.0 19.3 9.1 5.0 10.5 9.3 11.2 9.9 9.1 12.8 12.8 13.6 16.9 13.0 12.6 13.0 9.9 10.4 41.2 8.7 10.1 17.9 37.3 9.9 7.3 9.7 9.9 10.3 12.7 18.6 15.3 7.2 9.8 11.4 8.2 12.8 11.0 8.9 28.2 11.4 18.0 8.2 8.7 10.4 12.9 13.7 10.0 13.3 9.6 30.0 6.2 12.7 11.3 10.3 7.8 17.4 8.4 9.6 11.8 21.2 10.6 8.8 10.7 7.6 8.9 16.4 3.2 13.9 5.3 10.2 5.8 8.0 9.3 11.5 9.3 14.7 12.3 7.4 7.0 12.2 12.2 6.8 6.8 19.8 17.4 12.2 9.5 8.0 9.3 15.2 21.3 6.4 9.1 12.6 10.1 12.3 10.6 8.9 13.2 16.8 4.3 19.3 7.4 5.7 12.9 12.5 12.0 11.7 21.3 8.1 20.5 13.2 10.0 17.5 8.7 8.4 9.0 15.0 8.7 12.9 8.2 10.0 8.4 62.7 11.6 45.5 23.8 14.7 21.1 15.1 16.5 24.8 9.7 13.5 17.6 13.0 33.9 20.6 23.2 13.1 20.9 12.0 9.1 10.5 9.9 9.1 8.7 10.1 9.7 9.9 9.8 8.7 10.0 10.3 7.8 9.6 6.3 161.3 7.8 7.4 9.3 21.1 6.2 6.4 8.9 7.2 38.7 7.2 18.0 7.3 8.4 14.5 9.0 19.1 23.5 16.8 164.5 11.8 8.7 11.9 7.8 9.1 62.8 22.4 12.7 10.3 10.2 6.7 4.5 3.7 10.0 41.9 11.5 23.5 122.3 14.6 26.4 10.6 6.1 35.2 17.7 16.0 3.6 96.5 9.5 16.9 15.5 174.4 287.2 19.5 19.8 23.7 8.4 10.1 58.5 63.1 20.0 15.5 6.6 15.0 11.4 25.6 11.7 10.1 8.1 10.8 10.2 8.3 13.9 10.1 CREB1 ENSG00000118260 "CAMP responsive element binding protein 1" P16220 2 207529737-207605988 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Early spermatids: 417.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003803, HPA019150" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB003803: AB_562092, HPA019150: AB_1847220" "unprognostic (1.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.30e-2)" "unprognostic (2.69e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (8.41e-2)" "unprognostic (1.04e-2)" "unprognostic (2.53e-1)" "unprognostic (9.58e-2)" "unprognostic (1.74e-2)" "unprognostic (4.82e-3)" "unprognostic (5.53e-3)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "unprognostic (8.45e-2)" 13.0 8.7 10.6 15.3 11.4 22.4 14.7 17.5 11.1 15.8 11.9 11.4 10.0 15.7 10.8 15.0 13.1 14.0 11.5 10.3 10.7 12.4 11.6 13.6 22.1 10.6 9.9 17.2 8.7 15.6 6.9 18.0 10.4 13.0 14.0 17.8 8.9 12.6 6.7 11.5 10.6 16.3 9.7 17.1 12.1 32.4 9.9 28.7 18.1 14.6 25.0 16.8 9.6 15.0 24.9 20.9 38.6 15.6 22.9 22.4 21.8 15.9 23.5 26.6 26.5 21.6 22.9 15.4 19.8 21.1 29.8 19.5 34.8 20.4 37.7 25.1 13.2 29.2 18.9 23.0 18.7 27.7 20.0 16.0 16.3 21.1 31.1 25.4 34.9 28.9 20.5 22.5 30.4 16.8 41.0 16.1 27.8 24.2 13.1 31.4 22.1 20.2 25.1 24.6 27.1 23.4 21.6 16.2 18.1 35.5 16.5 30.1 18.5 21.8 22.6 22.1 20.5 19.6 27.5 36.4 25.2 25.3 22.0 33.6 28.2 28.2 27.0 29.2 23.7 36.7 25.3 26.2 34.1 34.8 30.0 20.7 56.1 45.6 34.9 18.6 38.6 26.7 10.6 11.4 17.5 11.1 10.3 10.7 10.6 9.9 10.4 9.7 9.9 15.0 46.7 19.2 18.2 47.0 52.3 70.9 47.1 33.3 34.1 38.9 25.3 18.5 26.3 17.2 29.0 12.9 33.3 29.1 35.5 25.3 23.5 23.6 417.8 19.6 39.2 47.2 32.4 54.7 56.1 20.3 24.9 35.8 18.8 21.0 43.7 41.5 35.7 15.8 29.4 40.4 51.1 28.2 30.5 48.8 75.9 47.2 26.1 35.8 44.4 68.4 60.9 42.1 33.0 66.9 70.7 26.4 27.5 29.3 29.1 56.5 22.8 19.7 18.9 40.2 39.5 37.4 40.7 44.5 29.4 33.5 57.8 18.6 42.6 19.6 25.7 62.6 CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9;salivary gland: 83.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.2;Gastric mucus-secreting cells: 105.0;Glandular and luminal cells: 120.5;Intestinal goblet cells: 280.5" "Cancer enhanced" "Detected in all" "prostate cancer: 87.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 134.3;BJ hTERT+: 130.7;BJ hTERT+ SV40 Large T+: 120.6;fHDF/TERT166: 321.8;OE19: 129.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA024069, CAB026151" Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB026151: , HPA024069: AB_1854750" "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.66e-3)" "unprognostic (2.93e-1)" "unprognostic (5.41e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.97e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (1.12e-2)" 8.6 15.1 4.3 8.0 3.3 0.1 10.7 0.9 4.2 43.2 2.1 41.2 27.7 20.4 2.4 3.2 5.2 25.0 15.6 7.2 3.4 2.8 1.1 14.8 0.7 1.9 5.1 9.3 133.9 2.3 10.7 26.7 4.1 42.3 43.3 0.1 83.0 26.8 4.4 5.6 30.6 13.3 1.1 3.2 68.0 3.9 8.4 1.0 4.5 4.2 4.7 21.4 15.3 2.4 0.9 0.8 1.3 26.1 81.9 77.9 0.6 134.3 130.7 120.6 83.3 13.7 0.3 0.0 0.7 321.8 8.3 0.0 1.6 0.4 66.6 0.1 1.5 2.0 0.8 0.0 113.5 0.0 1.9 75.2 0.0 68.6 2.5 109.0 1.0 0.5 11.2 0.0 102.5 0.0 0.1 0.4 17.0 129.0 13.7 0.1 18.0 0.2 0.2 0.0 0.0 0.2 0.9 3.4 0.2 23.3 0.1 4.9 0.0 62.7 18.3 48.6 83.4 0.1 0.1 0.0 75.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.3 0.9 4.2 7.2 3.4 1.9 5.1 4.1 1.1 8.4 2.4 10.3 0.0 46.4 0.3 0.6 1.5 44.4 2.6 0.0 0.0 52.0 5.1 15.9 25.8 10.0 29.5 0.0 1.2 0.1 56.8 3.9 42.0 2.1 37.2 24.1 9.0 9.1 0.0 2.1 89.2 2.3 49.4 105.0 120.5 4.5 1.9 3.3 0.0 1.9 0.0 1.0 280.5 6.1 0.0 3.5 6.6 83.6 1.0 10.6 2.8 2.0 0.0 0.0 19.6 0.1 49.2 59.8 44.4 0.2 40.4 9.5 0.7 3.6 0.0 0.0 0.7 29.3 1.0 1.5 0.6 2.3 3.4 1.8 10.7 57.7 51.3 CREB3L2 "BBF2H7, TCAG_1951439" ENSG00000182158 "CAMP responsive element binding protein 3 like 2" Q70SY1 7 137874979-138002086 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 141.1;Syncytiotrophoblasts: 144.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015068, HPA015534" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Endoplasmic reticulum" "HPA015068: AB_1847224, HPA015534: AB_2669210" "unprognostic (8.50e-2)" "unprognostic (3.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.50e-3)" "unprognostic (9.88e-2)" "unprognostic (9.09e-2)" "unprognostic (5.17e-2)" "unprognostic (4.50e-1)" "unprognostic (4.77e-1)" "unprognostic (8.93e-2)" "unprognostic (9.48e-2)" "unprognostic (9.65e-2)" "unprognostic (2.42e-1)" "unprognostic (3.08e-3)" "unprognostic (7.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.32e-2)" 20.7 29.7 8.3 18.5 13.9 23.8 22.8 8.3 12.2 30.3 46.5 22.4 22.3 33.9 26.8 15.0 22.6 15.0 25.9 8.1 9.6 19.6 12.5 19.3 12.8 13.2 10.8 29.0 30.1 59.5 25.1 39.4 12.1 21.6 17.6 5.0 28.7 23.2 6.1 8.7 22.9 29.2 9.6 13.0 17.4 9.0 16.1 10.0 65.3 9.4 20.4 19.5 19.9 17.3 13.1 19.9 37.6 0.6 62.9 61.7 28.1 65.1 104.0 44.4 44.7 27.5 11.7 2.6 16.8 71.1 24.1 6.9 21.9 47.1 86.9 19.1 10.8 83.4 26.7 67.6 41.4 25.3 115.5 25.4 29.2 56.0 65.3 45.5 59.7 6.5 43.8 37.4 52.9 23.5 8.0 31.6 13.6 17.9 13.7 17.5 19.8 22.1 35.3 13.2 9.4 22.3 21.1 54.0 29.1 21.7 7.9 18.9 63.1 59.5 8.7 72.3 24.2 43.9 16.2 16.9 70.9 71.3 135.0 10.4 5.5 6.0 7.3 3.0 9.8 3.9 5.4 8.2 5.7 3.9 2.0 3.4 2.0 7.2 1.6 11.9 12.5 3.2 8.3 13.9 8.3 12.2 8.1 9.6 13.2 10.8 12.1 9.6 16.1 17.3 30.6 6.4 25.9 18.6 27.3 12.2 9.7 18.9 8.0 12.0 32.0 25.4 17.5 21.5 34.9 23.9 10.4 62.6 39.5 24.7 13.7 10.2 56.3 18.1 86.6 31.6 15.7 12.0 7.5 17.6 93.0 49.6 16.3 42.4 49.4 27.8 29.6 24.3 56.3 15.2 10.6 21.0 20.3 34.9 25.6 18.7 61.8 30.7 26.6 63.7 21.4 5.4 40.2 55.8 48.0 14.4 18.2 103.0 141.1 35.1 66.2 7.9 22.4 12.3 39.5 62.3 50.2 3.4 7.4 9.5 7.1 144.5 26.6 11.1 17.0 44.0 CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880713 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004212, HPA055861" Supported Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Nuclear bodies" "CAB004212: AB_626817, HPA055861: AB_2682948" "unprognostic (1.17e-1)" "unprognostic (8.51e-2)" "unprognostic (1.60e-1)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (5.09e-2)" "unprognostic (9.59e-3)" "unprognostic (6.98e-2)" "unprognostic (8.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (2.84e-1)" "prognostic favorable (6.24e-5)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.97e-2)" "unprognostic (8.23e-2)" 17.4 10.6 5.8 17.1 5.2 52.9 16.8 25.4 11.5 20.9 3.7 18.8 12.5 26.5 12.4 16.5 22.4 16.6 14.4 5.9 3.1 12.0 14.3 15.9 17.6 8.9 6.8 37.3 29.7 18.5 11.3 16.9 2.9 16.1 14.1 13.8 17.2 16.2 29.6 21.0 16.4 19.6 0.4 21.0 16.3 33.2 7.9 29.1 23.3 28.9 20.7 16.6 16.5 6.4 12.3 31.0 39.3 17.4 23.5 23.1 20.4 17.4 28.9 29.2 28.2 28.2 22.4 33.7 20.1 33.3 18.7 23.2 45.7 14.2 32.9 57.5 18.5 26.6 29.2 17.9 26.0 26.9 36.5 20.7 14.2 32.5 38.9 18.0 22.3 17.0 30.9 44.8 16.0 42.0 17.9 13.0 32.3 11.7 12.7 83.4 31.1 26.1 11.2 16.2 32.6 21.5 29.5 28.7 16.8 25.3 25.6 25.9 34.7 35.5 35.2 18.4 16.0 20.8 24.3 63.7 7.2 15.8 25.6 1.9 1.1 0.9 1.7 1.5 0.8 3.7 0.8 1.3 0.7 2.1 0.8 1.1 6.7 1.4 2.9 1.5 0.8 0.9 5.8 5.2 25.4 11.5 5.9 3.1 8.9 6.8 2.9 0.4 7.9 6.4 48.1 44.8 51.6 91.1 38.3 56.2 31.0 16.0 27.3 34.2 34.4 25.7 41.2 40.0 28.0 11.0 25.0 17.4 50.1 31.2 5.9 20.9 43.0 37.2 56.4 35.7 15.0 33.4 88.7 20.3 11.3 39.5 32.1 63.5 30.4 53.1 32.5 29.5 20.9 28.6 89.8 25.3 18.3 44.0 42.8 80.2 56.5 49.0 17.8 87.1 52.5 34.5 43.3 111.6 101.2 27.5 19.5 51.1 35.6 39.8 25.2 10.9 28.2 17.6 46.0 75.8 44.9 35.1 42.2 34.6 58.8 30.8 44.2 36.2 24.6 44.2 CRLF2 "CRL2, TSLPR" ENSG00000205755 "Cytokine receptor like factor 2" Q9HC73 X 1187549-1212723 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.8;gallbladder: 1.3;lymphoid tissue: 1.5" "Cell type enriched" "Detected in some" 4 "monocytes: 100.2" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.2" "Cell line enriched" "Detected in some" 4 "HMC-1: 16.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (7.84e-2)" "unprognostic (7.99e-4)" "unprognostic (6.02e-3)" "unprognostic (2.01e-2)" "unprognostic (1.15e-3)" "unprognostic (2.31e-6)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "unprognostic (4.59e-3)" "unprognostic (1.09e-1)" "unprognostic (1.46e-2)" "unprognostic (9.72e-3)" "unprognostic (6.88e-5)" "unprognostic (7.09e-3)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.62e-1)" 0.2 0.0 0.0 1.5 0.0 1.8 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.2 0.3 0.2 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.1 0.5 0.6 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.5 0.8 0.1 0.3 2.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.3 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.6 0.9 3.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.3 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.0 1.8 0.0 1.0 100.2 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "liver: 9388.5" "Group enriched" "Detected in some" 16 "Ductal cells: 1087.7;Hepatocytes: 4142.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 1010.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 6.3;U-2 OS: 4.5;U-266/84: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" NA NA 2920000000 5200000000 "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: AB_562362, HPA027367: AB_1847216, HPA027396: AB_1847217" "unprognostic (3.74e-1)" "unprognostic (5.31e-2)" "unprognostic (2.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (4.17e-10)" "unprognostic (3.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.60e-2)" "unprognostic (6.61e-2)" 3.4 0.7 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.3 0.0 3.1 0.0 0.5 0.4 111.7 0.7 0.0 0.0 0.7 9388.5 0.5 0.1 0.0 0.0 0.4 118.5 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.3 0.6 0.5 0.0 0.0 6.1 0.4 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.8 0.0 11.7 1.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 118.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1087.7 1.4 0.0 0.1 6.3 0.0 163.2 0.0 63.2 0.0 0.0 0.0 0.2 0.0 0.0 89.6 4142.7 0.1 0.0 0.0 0.0 0.0 98.8 0.3 0.7 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 60.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 CRTC1 "FLJ14027, KIAA0616, MECT1, TORC1" ENSG00000105662 "CREB regulated transcription coactivator 1" Q6UUV9 19 18683678-18782333 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 37.4;Horizontal cells: 43.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 203 "amygdala: 14.2;basal ganglia: 11.4;cerebellum: 27.1;cerebral cortex: 24.3;hippocampal formation: 24.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022035, HPA063619" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear bodies" "Plasma membrane, Cytosol" "HPA022035: AB_1847255, HPA063619: " "unprognostic (5.95e-3)" "unprognostic (2.57e-1)" "unprognostic (9.94e-2)" "unprognostic (8.62e-3)" "unprognostic (9.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (5.57e-2)" "unprognostic (2.27e-1)" "unprognostic (6.68e-2)" "prognostic favorable (1.80e-5)" "unprognostic (3.37e-2)" "prognostic favorable (3.83e-5)" "unprognostic (6.83e-3)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (2.03e-2)" 8.8 11.3 14.2 5.2 11.4 2.1 8.2 27.1 24.3 11.3 0.0 8.9 4.0 9.3 3.4 5.2 10.3 3.2 10.5 24.5 0.0 12.8 10.4 7.9 4.1 0.0 0.0 9.4 9.8 4.7 23.7 3.9 0.0 11.6 1.5 4.4 7.3 5.1 14.4 7.4 8.5 2.5 0.0 9.6 9.9 11.3 0.0 3.6 14.4 3.6 2.2 9.7 7.4 0.0 5.2 7.9 6.7 10.7 6.3 4.5 18.6 5.4 3.6 5.3 4.8 5.1 6.6 7.1 11.6 5.2 3.9 5.5 2.1 3.5 1.3 3.1 15.1 6.0 7.8 9.3 5.5 8.3 16.3 7.8 2.9 4.4 1.3 6.8 3.1 7.2 4.8 6.3 3.0 15.2 5.7 10.0 8.8 2.7 13.1 8.7 2.9 8.1 3.2 8.0 12.1 10.7 6.0 5.8 7.0 2.2 6.6 5.2 5.4 6.0 9.1 10.8 6.4 4.4 3.6 4.6 6.9 8.6 4.6 0.3 0.6 0.4 0.4 0.2 0.3 0.5 0.5 0.6 0.7 0.7 0.5 0.3 0.2 0.3 0.4 0.8 0.4 0.4 14.2 11.4 27.1 24.3 24.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 5.3 31.0 6.9 2.7 8.9 7.8 5.7 29.1 5.8 6.1 17.7 10.0 3.5 18.4 27.1 9.7 7.9 6.8 11.7 4.6 1.1 9.6 14.0 5.6 19.2 3.6 37.4 6.0 2.7 7.5 8.6 9.8 2.5 14.7 3.9 4.7 8.8 43.7 26.7 7.1 12.2 6.0 4.0 3.2 9.3 6.3 3.6 10.3 5.5 9.1 8.2 12.1 20.2 3.5 9.6 4.9 2.0 3.0 6.1 5.0 4.8 14.7 0.0 14.2 6.6 2.9 8.8 2.4 2.0 10.4 5.1 8.3 5.2 3.6 CRTC3 FLJ21868 ENSG00000140577 "CREB regulated transcription coactivator 3" Q6UUV7 15 90529923-90645345 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043735, HPA063691" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Cytosol "HPA043735: AB_10794286, HPA063691: AB_2685092" "unprognostic (7.60e-2)" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.51e-1)" "unprognostic (1.75e-2)" "unprognostic (1.69e-1)" "unprognostic (6.48e-2)" "unprognostic (3.60e-1)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (5.22e-3)" "unprognostic (4.67e-2)" "unprognostic (9.32e-2)" "unprognostic (9.51e-2)" "unprognostic (2.30e-1)" 27.0 15.5 16.8 14.2 25.3 10.7 21.7 20.0 19.8 26.3 10.1 28.4 7.3 26.0 10.9 12.5 23.8 14.8 19.8 17.0 16.4 14.5 13.2 23.2 15.8 21.8 23.1 36.8 10.7 13.8 9.9 17.1 21.1 18.8 9.4 13.5 17.4 17.0 19.9 19.1 16.6 20.9 16.3 13.3 15.2 16.8 23.2 15.0 22.3 17.4 15.7 28.4 18.3 31.6 9.6 15.1 9.7 16.7 21.6 15.7 46.0 11.7 16.0 17.6 15.9 12.4 9.3 0.2 8.3 23.8 14.9 15.2 15.1 9.8 13.2 16.3 18.8 23.7 83.9 6.1 24.8 6.5 38.8 17.2 16.3 14.5 19.3 13.2 12.5 10.2 12.8 5.5 13.6 11.5 2.6 9.7 3.7 2.7 7.2 8.3 16.3 0.5 6.6 20.3 18.5 16.5 34.7 11.6 19.3 10.8 11.2 12.2 16.4 19.7 14.9 19.0 14.0 7.3 10.2 7.2 8.0 12.6 9.8 21.4 2.6 1.5 3.5 0.8 3.8 2.9 4.3 3.7 1.6 5.0 6.1 3.9 0.5 3.3 0.3 2.1 4.4 3.4 16.8 25.3 20.0 19.8 17.0 16.4 21.8 23.1 21.1 16.3 23.2 31.6 17.9 6.4 9.2 44.1 35.6 23.6 27.8 8.0 13.1 24.9 15.7 12.7 17.0 14.3 7.8 12.9 27.1 14.8 30.0 8.6 1.9 14.9 29.3 6.6 18.5 20.4 15.6 17.1 70.1 10.7 43.3 23.2 14.8 12.7 23.5 34.8 24.7 16.2 15.3 57.2 72.4 9.1 6.1 18.2 18.8 24.3 26.8 21.7 17.8 39.4 20.6 17.7 58.7 75.4 160.8 11.1 10.9 43.6 21.3 26.2 6.4 11.0 2.8 59.7 46.0 30.5 45.8 10.2 17.8 11.4 24.0 17.8 36.0 13.7 11.3 38.2 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5623.2;heart muscle: 10683.1;skeletal muscle: 6972.0;tongue: 9406.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 2889.5;Cardiomyocytes: 6878.2;Muller glia cells: 1664.3;Proximal tubular cells: 7285.9" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ASC diff: 2663.1;fHDF/TERT166: 775.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" 1035.0 106.6 2466.0 113.9 3113.8 0.4 592.2 3032.2 5623.2 439.1 2077.7 678.9 24.6 351.4 179.1 312.2 204.0 71.7 10683.1 2424.9 2666.2 2123.2 37.2 253.4 15.0 3215.2 2856.7 136.0 50.6 24.9 209.2 107.8 3147.1 317.9 78.2 478.7 428.7 358.5 6972.0 317.3 158.5 338.1 2877.3 88.5 263.8 23.5 2815.5 20.9 477.7 9406.7 34.4 490.0 477.5 4060.6 0.1 0.5 0.1 45.0 2663.1 90.9 15.0 54.5 2.5 0.8 2.5 1.7 0.2 0.0 41.7 775.8 0.2 2.0 1.8 2.3 1.4 0.3 0.0 0.0 11.9 3.9 16.9 0.4 0.7 77.1 11.1 0.6 6.2 44.3 0.2 0.0 4.6 2.5 169.5 0.1 0.1 1.1 0.5 0.0 1.0 0.2 0.0 0.6 29.8 0.8 0.1 0.4 5.3 9.1 39.8 63.5 4.9 0.0 1.7 310.1 105.0 6.5 4.1 0.5 0.1 0.6 7.1 0.4 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2466.0 3113.8 3032.2 5623.2 2424.9 2666.2 3215.2 2856.7 3147.1 2877.3 2815.5 4060.6 38.4 83.3 4.1 96.0 51.3 174.9 2889.5 32.1 72.8 16.2 334.4 696.1 6878.2 84.4 15.2 1338.9 18.8 3.9 6.8 0.4 677.0 320.3 24.7 345.4 265.3 88.4 7.1 0.0 6.7 11.5 7.4 880.6 0.0 1008.4 0.0 16.1 35.7 0.7 5.8 10.1 12.6 2.4 8.2 0.3 85.8 12.6 228.6 67.7 483.8 11.2 3.6 1664.3 0.0 7.5 615.7 12.1 0.0 187.7 1.6 855.4 0.0 7285.9 23.2 59.4 138.1 799.9 1053.3 21.6 1.4 56.5 155.1 33.4 55.4 6.7 1.2 249.0 CSDE1 "D1S155E, UNR" ENSG00000009307 "Cold shock domain containing E1" O75534 1 114716913-114758676 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1408.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 2403.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018846, HPA052221" Supported Enhanced "Plasma membrane,Cytosol" NA NA 100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA018846: AB_1847266, HPA052221: AB_2681767" "unprognostic (2.84e-1)" "unprognostic (9.18e-3)" "unprognostic (4.86e-3)" "unprognostic (3.30e-3)" "unprognostic (2.83e-2)" "unprognostic (4.51e-2)" "unprognostic (5.32e-3)" "unprognostic (5.16e-2)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (2.40e-1)" "unprognostic (4.69e-2)" "unprognostic (4.67e-2)" "unprognostic (1.18e-1)" "unprognostic (5.17e-3)" "unprognostic (2.54e-2)" 412.5 166.8 149.0 170.9 168.8 276.4 241.9 160.5 170.8 193.8 163.5 300.1 187.3 226.7 196.2 247.2 162.9 172.0 414.8 137.6 169.8 228.2 233.6 182.8 172.4 166.4 169.5 258.8 216.2 273.8 85.8 182.4 172.6 229.8 199.6 177.6 230.0 245.6 1408.6 201.6 196.1 236.4 172.2 176.5 201.7 257.4 164.7 218.8 262.6 1039.4 208.2 238.4 137.0 187.3 658.8 226.6 395.5 396.1 440.7 561.4 550.1 566.7 420.5 373.0 301.1 334.0 193.7 514.9 465.6 543.1 217.0 272.3 442.4 439.6 539.2 632.1 302.8 506.1 390.3 299.9 388.2 380.7 288.7 414.7 468.2 447.0 583.2 502.2 433.5 426.5 523.3 327.3 458.9 2403.4 513.8 242.0 755.0 274.0 302.5 378.4 1221.9 244.0 295.4 508.4 485.6 320.7 553.9 455.8 433.3 411.9 234.5 599.4 526.9 437.8 597.3 579.6 629.1 495.7 587.9 567.7 564.9 422.2 1365.1 217.2 241.4 230.8 146.4 233.1 199.7 161.6 186.5 180.7 226.8 130.4 219.3 189.1 155.2 191.0 270.8 87.2 222.2 389.4 149.0 168.8 160.5 170.8 137.6 169.8 166.4 169.5 172.6 172.2 164.7 187.3 193.2 198.7 194.2 41.8 198.3 216.2 219.7 149.0 235.6 134.0 218.2 161.5 572.0 160.2 181.1 128.8 58.4 172.4 155.2 160.8 226.9 198.2 405.5 130.4 178.8 191.3 219.9 232.8 70.8 202.9 208.2 181.7 143.2 174.3 219.1 234.7 156.4 189.1 156.8 99.3 73.7 220.3 120.1 277.9 202.0 639.7 161.8 216.8 220.5 55.3 241.8 195.5 117.4 54.3 86.5 213.8 150.6 225.7 283.6 269.0 240.1 235.5 143.2 121.3 164.3 232.4 274.2 263.3 189.8 247.2 234.0 272.9 193.3 208.2 210.5 283.8 CSE1L "CAS, CSE1, XPO2" ENSG00000124207 "Chromosome segregation 1 like" P55060 20 49046246-49096960 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 164.0;Spermatogonia: 121.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002140, HPA038059, HPA038060" Enhanced Enhanced Nucleoplasm,Cytosol No Yes 320000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB002140: AB_563461, HPA038059: AB_2675811, HPA038060: AB_2675812" "unprognostic (4.01e-2)" "unprognostic (3.15e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.91e-5)" "unprognostic (4.86e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-8)" "unprognostic (3.44e-2)" "unprognostic (1.45e-2)" "unprognostic (2.63e-2)" "unprognostic (2.72e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (2.59e-1)" "unprognostic (4.84e-1)" "unprognostic (5.71e-1)" "prognostic unfavorable (6.91e-4)" 23.6 24.5 16.0 29.0 20.2 26.4 34.2 26.6 21.1 25.7 12.9 23.6 19.8 28.1 23.8 38.2 27.0 19.0 24.7 17.1 18.0 29.8 30.9 19.7 35.0 21.0 17.3 27.2 20.4 30.8 13.6 37.5 22.8 25.8 28.7 23.2 21.7 25.6 39.8 34.4 19.2 35.0 21.1 20.3 20.7 87.7 17.0 40.7 23.4 41.5 42.8 27.5 22.2 29.1 224.3 152.4 182.1 140.9 69.0 88.5 196.7 172.1 90.5 528.1 222.0 501.8 175.4 227.3 224.1 109.7 213.9 251.4 270.7 322.9 500.0 37.4 131.3 158.0 166.1 244.7 42.0 176.2 83.3 50.0 118.7 259.0 148.7 72.4 177.5 124.3 227.2 87.1 201.1 76.8 213.9 90.6 153.5 185.1 224.0 133.9 299.5 176.4 116.5 153.2 159.6 92.6 275.2 293.3 97.1 137.7 245.3 113.3 115.5 279.3 233.9 166.4 247.9 50.5 130.8 210.8 166.8 139.5 152.2 18.6 16.3 3.8 13.8 20.6 21.1 16.7 21.0 17.1 20.1 13.6 22.1 19.3 4.4 23.0 23.6 8.9 20.1 18.3 16.0 20.2 26.6 21.1 17.1 18.0 21.0 17.3 22.8 21.1 17.0 29.1 16.4 6.4 26.8 8.1 20.3 30.2 25.8 29.5 31.3 14.9 17.4 15.9 26.6 24.3 22.4 27.6 10.4 71.8 15.7 7.4 13.7 32.2 95.9 14.7 19.4 22.9 5.4 40.4 20.9 26.6 61.2 24.6 13.7 17.8 4.5 35.1 19.2 26.7 29.7 15.2 24.4 11.8 20.3 17.9 21.9 57.8 25.4 17.9 26.6 9.4 28.0 22.6 7.2 17.1 41.7 26.7 10.0 31.6 26.7 28.8 9.9 21.6 21.7 15.5 39.5 19.3 22.1 164.0 121.5 36.7 34.5 72.7 17.5 31.1 23.7 22.2 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 2.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 11.4;Basal respiratory cells: 11.3;dendritic cells: 17.7;Ductal cells: 18.3;Pancreatic endocrine cells: 24.9;T-cells: 28.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.2" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.2" "Cell line enriched" "Detected in some" 4 "BJ hTERT+: 91.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" NA NA 23900 "Cluster 15: NK-cells - Transcription" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA057404: AB_2683428, HPA062006: AB_2684654" "unprognostic (7.29e-2)" "unprognostic (2.49e-3)" "unprognostic (8.77e-2)" "unprognostic (2.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (1.47e-2)" "unprognostic (2.64e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-8)" "unprognostic (4.81e-2)" "unprognostic (1.22e-1)" "unprognostic (9.07e-2)" "unprognostic (2.06e-2)" 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 2.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 9.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 91.3 0.1 5.1 0.0 7.4 0.0 1.5 0.0 5.3 0.2 0.0 6.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 20.8 13.8 2.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.3 3.8 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 11.4 0.0 0.3 1.5 0.1 11.3 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 17.7 0.1 0.0 18.3 0.0 0.3 0.2 4.8 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.7 1.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.6 0.0 28.6 0.0 0.0 1.1 CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 64.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 248.5;Extravillous trophoblasts: 124.6;Langerhans cells: 365.1;Macrophages: 114.5;monocytes: 575.2;Syncytiotrophoblasts: 312.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 320.2" "Group enriched" "Detected in all" 30 "dendritic cells: 170.7;granulocytes: 320.2;monocytes: 161.1" "Group enriched" "Detected in some" 7 "BEWO: 194.0;HMC-1: 58.3;SK-MEL-30: 142.0" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" NA NA 13000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "CAB016148: AB_626868" "unprognostic (4.19e-2)" "prognostic favorable (2.38e-5)" "unprognostic (5.47e-2)" "unprognostic (4.33e-2)" "unprognostic (4.88e-2)" "prognostic favorable (2.81e-4)" "unprognostic (8.24e-2)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (8.48e-2)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (5.53e-4)" "unprognostic (3.60e-1)" "unprognostic (9.44e-2)" 10.0 5.5 4.2 25.4 4.4 21.7 6.8 5.2 4.8 5.1 5.4 5.8 5.8 2.5 1.7 5.3 4.1 12.6 2.5 4.0 5.4 2.3 4.6 14.2 20.9 8.5 6.6 1.8 3.3 3.1 1.4 64.4 8.3 2.5 7.4 0.7 3.0 3.0 0.6 4.0 6.6 7.1 7.2 14.9 5.0 1.1 9.0 9.4 1.6 2.0 23.5 12.7 1.5 11.9 0.3 11.5 0.5 0.0 0.0 0.0 194.0 0.3 0.5 0.4 0.1 4.2 1.0 0.2 12.6 0.0 10.3 0.2 0.1 0.0 0.0 3.9 0.1 0.2 8.0 0.1 0.0 4.6 58.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.2 0.4 18.8 1.6 1.8 0.4 0.2 0.5 0.3 0.0 0.5 0.1 0.3 3.7 0.1 142.0 15.1 9.4 16.8 0.0 0.2 5.5 0.1 0.0 0.1 0.1 0.6 0.0 18.5 0.1 17.4 161.1 200.3 0.4 94.9 1.0 2.3 0.3 0.3 170.7 0.6 0.4 0.3 320.2 7.3 48.7 164.0 1.1 65.5 4.2 4.4 5.2 4.8 4.0 5.4 8.5 6.6 8.3 7.2 9.0 11.9 1.2 0.0 7.3 1.3 5.5 7.8 0.9 0.1 0.6 0.6 6.3 2.5 1.2 2.8 3.6 1.8 0.0 248.5 38.3 0.0 0.0 0.3 0.6 7.8 1.2 5.3 0.0 1.3 1.4 1.8 124.6 3.4 0.0 14.7 10.1 0.5 0.7 0.1 75.5 0.0 1.7 0.0 2.0 74.8 365.1 0.3 0.9 114.5 8.8 66.5 575.2 0.3 0.0 1.5 0.9 0.2 0.0 0.4 1.0 0.5 0.0 0.1 2.7 1.5 6.6 1.8 1.4 0.2 0.4 0.0 5.3 312.5 3.3 0.1 0.0 2.5 CSF3 "C17orf33, G-CSF, GCSF, MGC45931" ENSG00000108342 "Colony stimulating factor 3" P09919 17 40015361-40017813 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 123.0;urinary bladder: 57.5" "Cell type enhanced" "Detected in some" "Adipocytes: 57.0;Alveolar cells type 2: 121.2;Basal respiratory cells: 155.9;Club cells: 85.8;Endothelial cells: 192.1;Fibroblasts: 101.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 74.8;U-87 MG: 286.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 6170 "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.59e-3)" "unprognostic (1.57e-2)" "unprognostic (1.73e-1)" "prognostic favorable (8.45e-4)" "unprognostic (1.06e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-2)" "unprognostic (1.74e-1)" "unprognostic (2.26e-1)" "unprognostic (2.82e-2)" "unprognostic (7.40e-4)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (4.10e-2)" "unprognostic (4.80e-3)" 41.7 5.9 1.3 14.2 1.2 3.5 7.3 0.9 1.5 25.2 0.7 8.5 0.0 4.1 0.0 6.2 7.2 2.3 16.5 1.1 1.0 3.1 0.5 123.0 0.3 2.0 1.2 1.9 3.8 0.3 10.2 2.5 1.6 16.1 0.5 0.3 3.0 0.1 21.7 1.8 4.3 1.6 2.0 0.9 8.0 1.3 1.3 0.3 3.9 10.5 0.4 57.5 5.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 74.8 0.0 2.8 0.2 0.0 0.0 1.0 0.0 3.2 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 36.0 11.6 0.0 9.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 286.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.9 1.5 1.1 1.0 2.0 1.2 1.6 2.0 1.3 1.1 57.0 22.4 121.2 0.0 0.0 34.5 5.3 155.9 0.0 0.0 0.1 0.1 0.1 0.0 85.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 11.4 0.8 192.1 0.0 0.0 0.0 0.2 0.0 101.5 5.6 23.6 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 18.3 0.0 36.5 0.0 0.0 2.2 39.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 14.0 0.0 0.0 34.9 0.0 0.0 37.3 6.4 0.2 0.9 0.9 33.5 0.0 3.2 0.0 0.8 17.3 CSF3R "CD114, GCSFR" ENSG00000119535 "Colony stimulating factor 3 receptor" Q99062 1 36466043-36483278 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 379.7;lung: 136.7;lymphoid tissue: 375.6;placenta: 105.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 230.8;Cytotrophoblasts: 423.8;Kupffer cells: 177.7;monocytes: 197.6;Syncytiotrophoblasts: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 1962.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 1962.3" "Group enriched" "Detected in some" 18 "BEWO: 70.8;NB-4: 20.3;THP-1: 50.3;U-937: 47.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017116, HPA048086" Enhanced "Intracellular and membrane" NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB017116: , HPA048086: AB_2680257" "unprognostic (5.57e-3)" "unprognostic (8.05e-2)" "unprognostic (7.23e-2)" "unprognostic (3.87e-2)" "unprognostic (2.88e-1)" "unprognostic (2.92e-2)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (5.72e-4)" "unprognostic (6.33e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (2.03e-1)" "unprognostic (2.31e-2)" 36.2 7.1 5.8 148.2 5.6 379.7 13.0 6.7 19.0 5.2 6.3 6.4 2.6 3.1 0.4 5.6 31.5 15.8 14.6 5.5 7.3 9.7 22.9 136.7 7.3 10.3 7.8 3.2 4.9 1.6 5.5 105.1 11.4 7.5 1.8 0.1 7.4 1.8 3.6 1.6 9.8 12.2 9.6 375.6 9.9 1.2 10.7 5.7 5.8 21.7 2.7 22.2 6.2 11.9 0.0 0.0 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 1.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 1.5 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 47.8 0.0 1.1 280.8 8.7 0.2 56.8 0.6 0.1 0.4 0.2 97.2 0.4 0.1 0.3 1962.3 3.4 24.1 3.3 0.6 158.4 5.8 5.6 6.7 19.0 5.5 7.3 10.3 7.8 11.4 9.6 10.7 11.9 0.7 25.6 230.8 0.0 3.3 1.0 0.5 0.0 0.0 0.0 5.9 4.7 1.8 0.0 10.0 0.0 0.0 423.8 2.9 0.0 0.0 0.0 0.4 0.3 6.4 4.8 0.0 4.6 0.2 0.0 47.3 8.0 1.5 0.2 18.9 1.1 3.9 1.2 64.1 0.0 0.2 0.0 0.0 177.7 39.2 0.7 0.3 111.5 0.0 77.8 197.6 0.2 6.2 0.5 0.3 0.1 0.0 0.0 0.7 0.3 0.0 0.5 6.6 0.2 0.0 0.3 1.0 0.0 0.4 0.2 0.1 1194.8 4.0 0.0 0.0 3.0 CSN1S1 "CASA, CSN1" ENSG00000126545 "Casein alpha s1" P47710 4 69931068-69946574 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "breast: 1391.5" "Cell type enriched" "Detected in some" 47 "Breast glandular cells: 8261.0" "Cancer enriched" "Detected in some" 10 "breast cancer: 17.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035659, HPA057031" Enhanced "Secreted in female reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA035659: AB_10696356, HPA057031: AB_2683315" "unprognostic (1.52e-2)" "unprognostic (1.01e-1)" 16.0 0.0 0.1 0.5 0.0 0.0 1391.5 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.4 1.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.2 0.0 0.1 0.0 0.4 0.1 28.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 8261.0 172.2 2.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.1 0.3 0.0 2.1 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.0 0.0 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 280.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavorable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavorable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 87.1 52.8 81.1 41.2 82.6 51.6 88.3 80.8 95.1 93.6 66.0 73.0 41.4 82.7 52.5 69.0 83.3 48.7 80.9 82.9 73.7 70.2 37.4 92.2 40.3 78.9 78.6 109.5 64.9 74.1 85.1 71.2 79.5 80.3 35.5 47.3 71.6 44.9 60.5 94.8 50.9 45.3 70.2 63.6 58.0 29.5 83.2 33.3 64.4 47.2 37.8 65.7 88.4 93.9 101.5 57.4 121.6 114.7 61.5 88.3 92.1 126.9 168.6 116.7 114.3 63.9 76.7 74.2 53.0 120.7 70.7 77.9 96.1 177.9 79.2 123.0 215.2 23.9 181.2 47.4 123.7 48.3 61.9 90.2 143.8 171.7 220.3 141.0 121.1 60.6 50.9 155.0 110.8 68.4 71.1 60.9 87.2 67.3 69.1 130.8 90.1 123.4 99.0 92.4 181.6 69.3 102.9 109.3 124.7 68.0 59.5 73.0 134.3 94.0 111.3 58.7 102.1 61.2 105.2 104.5 151.0 56.9 176.3 4.8 1.6 3.6 3.0 0.8 3.8 2.1 3.4 3.0 1.8 3.1 1.9 2.5 3.8 5.7 0.5 15.9 1.6 1.2 81.1 82.6 80.8 95.1 82.9 73.7 78.9 78.6 79.5 70.2 83.2 93.9 73.4 38.5 21.7 0.0 32.3 78.6 158.8 89.1 68.9 132.6 53.7 42.4 49.8 34.3 73.9 23.9 60.5 35.2 42.3 28.4 7.9 30.8 46.0 94.3 72.5 76.4 62.8 12.6 0.0 41.8 49.2 60.8 39.8 126.5 3.8 46.6 45.0 21.3 23.1 72.3 0.0 46.0 46.8 17.6 54.1 69.1 85.4 21.8 60.5 0.0 13.3 117.9 28.8 0.0 0.0 57.5 33.1 66.2 83.5 160.5 9.0 6.5 62.8 60.7 72.3 85.7 98.0 8.0 20.0 50.3 104.7 125.5 26.0 34.9 37.6 280.8 CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58198106 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 112.7" "Group enriched" "Detected in all" 5 "Early spermatids: 227.4;Late spermatids: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 92000 "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "unprognostic (9.49e-2)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.40e-5)" "prognostic unfavorable (1.80e-4)" "unprognostic (6.84e-3)" "unprognostic (2.93e-3)" "unprognostic (2.40e-1)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (2.06e-3)" "unprognostic (7.07e-2)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" 21.0 14.1 19.3 9.0 20.2 6.4 19.0 18.9 22.1 23.0 23.7 32.1 10.0 21.0 29.0 15.7 20.3 14.1 21.2 20.0 19.7 17.3 15.9 16.2 14.2 19.1 20.4 32.4 34.2 23.9 15.7 15.5 19.2 15.5 12.4 13.5 17.0 16.7 41.1 64.8 14.2 21.9 19.8 12.6 27.9 112.7 20.3 18.3 18.0 26.8 17.3 24.2 19.6 19.9 28.1 35.3 24.5 19.1 46.2 62.5 27.6 24.7 41.8 47.7 30.7 64.0 23.2 44.2 38.8 29.6 18.9 29.2 41.6 37.2 53.4 16.9 28.3 23.4 18.0 56.1 66.5 32.6 20.5 66.9 88.9 33.8 65.9 62.0 45.4 43.6 53.4 15.1 31.0 15.8 41.2 21.9 23.4 16.6 45.7 48.4 38.7 25.7 33.1 28.7 20.5 18.4 39.7 20.3 63.6 41.9 13.9 24.6 33.6 27.8 33.7 23.3 25.7 36.2 30.2 63.2 24.3 21.8 24.4 1.1 0.2 0.3 0.7 0.1 0.4 0.6 1.1 0.4 0.2 0.6 1.8 1.3 0.0 0.7 0.1 1.9 0.0 0.1 19.3 20.2 18.9 22.1 20.0 19.7 19.1 20.4 19.2 19.8 20.3 19.9 30.6 12.8 22.5 19.2 16.7 29.6 10.9 13.0 8.6 24.0 19.3 19.9 24.4 12.8 7.6 9.2 4.2 15.9 28.3 16.4 7.9 14.5 227.4 24.7 37.8 25.8 16.8 10.3 27.7 17.2 26.1 17.7 8.6 29.5 8.2 37.0 19.6 17.0 16.9 18.5 19.1 11.9 4.1 25.5 23.0 281.0 14.3 23.1 12.4 20.6 14.2 25.3 18.6 20.6 26.1 25.0 11.5 19.5 9.2 18.1 16.0 16.3 13.4 21.7 13.1 29.2 23.2 48.1 36.8 12.6 29.0 24.5 20.3 35.6 17.5 23.0 CSNK2B "Ckb1, Ckb2" ENSG00000204435 "Casein kinase 2 beta" P67870 6 31665227-31670343 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004349, HPA005944, CAB013087, CAB016059" Approved NA NA 83000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "CAB004349: AB_626791, CAB013087: AB_2533571, CAB016059: AB_626792, HPA005944: AB_1847290" "unprognostic (1.61e-1)" "unprognostic (3.21e-2)" "unprognostic (8.88e-2)" "unprognostic (1.55e-3)" "unprognostic (9.51e-2)" "unprognostic (1.38e-1)" "unprognostic (3.03e-3)" "unprognostic (1.60e-1)" "unprognostic (7.52e-2)" "unprognostic (1.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (5.88e-2)" "unprognostic (1.72e-1)" "unprognostic (9.67e-2)" "unprognostic (3.72e-2)" 155.8 157.4 15.8 31.9 24.6 62.2 150.2 17.6 54.1 147.9 16.8 142.2 27.8 126.7 183.7 166.6 130.1 33.1 178.9 15.9 16.4 172.1 163.7 133.0 72.5 16.3 17.5 161.2 142.3 69.3 130.0 68.2 17.8 120.3 50.4 41.4 131.9 57.6 232.0 294.2 126.5 66.3 15.4 146.0 146.7 257.9 17.1 56.5 132.4 94.8 30.1 126.2 139.8 17.4 0.9 95.5 2.5 164.9 97.4 158.0 120.8 200.9 350.2 407.6 377.9 0.2 129.3 302.5 127.9 196.8 146.0 0.1 1.0 374.5 409.4 153.1 322.6 4.3 0.6 1.1 260.0 341.5 0.9 257.8 1.5 0.8 0.2 0.2 4.7 208.3 1.7 1.7 0.8 2.9 237.1 2.2 102.0 240.0 0.0 221.1 2.3 247.7 222.3 136.5 1.2 243.0 1.8 0.9 175.8 101.0 7.4 1.3 118.8 210.3 203.9 198.0 1.3 167.3 285.9 267.6 122.3 1.6 196.1 87.3 114.8 121.8 80.1 125.9 80.5 113.7 81.7 85.1 111.0 99.1 71.4 61.9 95.2 90.8 83.2 131.7 113.4 95.0 15.8 24.6 17.6 54.1 15.9 16.4 16.3 17.5 17.8 15.4 17.1 17.4 114.3 51.3 67.0 11.1 124.4 186.1 125.1 196.1 138.9 56.8 135.5 196.3 91.3 105.8 116.5 101.2 12.5 211.8 106.4 185.6 270.1 184.7 452.7 75.1 71.7 122.7 125.7 103.5 14.1 175.2 252.7 118.3 93.3 68.2 129.5 102.3 125.7 126.6 296.2 48.8 14.3 175.4 138.4 204.4 218.5 270.7 153.7 146.2 152.9 8.4 181.1 168.3 121.5 14.6 19.1 182.9 248.1 125.3 152.1 154.3 283.1 397.5 91.3 47.8 138.1 107.9 152.2 485.6 186.5 142.7 186.3 282.1 111.5 116.8 184.3 150.6 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 761.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Club cells: 115.2;Pancreatic endocrine cells: 368.1;Respiratory ciliated cells: 404.0" "Group enriched" "Detected in many" 5 "thyroid cancer: 171.0;urothelial cancer: 43.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 130.2;CAPAN-2: 364.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 82000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "CAB019316: , HPA044963: AB_2679158" "unprognostic (3.01e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (5.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (5.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.29e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (5.89e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-2)" "unprognostic (2.59e-2)" 3.2 0.3 0.1 0.3 0.1 0.2 28.5 0.8 0.4 7.4 0.8 0.4 0.0 0.3 0.6 34.6 14.9 0.5 2.8 0.1 0.3 2.6 0.3 18.3 0.0 0.2 0.2 0.7 0.7 2.1 1.6 8.1 0.1 0.9 0.0 0.0 7.4 4.9 2.0 761.4 0.3 0.1 0.1 0.2 0.6 1.8 0.4 2.7 21.4 0.0 2.2 1.2 22.5 0.2 130.2 0.0 0.0 0.6 0.0 0.0 37.6 1.4 0.0 0.3 0.2 1.0 364.6 0.0 1.8 5.1 0.1 4.5 0.0 32.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.5 0.8 0.2 0.7 0.0 0.0 35.8 0.4 0.1 0.8 0.1 0.0 0.2 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.4 0.1 0.3 0.2 0.2 0.1 0.1 0.4 0.2 0.1 93.0 6.1 0.0 0.6 1.1 1.7 41.4 0.6 0.0 5.3 7.1 1.2 0.0 115.2 58.8 0.0 33.3 0.0 0.1 0.0 57.4 0.2 7.7 0.1 0.9 0.0 0.0 0.0 21.6 24.4 2.0 0.0 0.6 21.6 0.1 0.4 0.1 41.1 0.0 0.0 0.0 24.4 1.4 10.0 0.8 0.0 5.3 5.4 0.0 1.1 1.3 0.0 0.0 0.0 368.1 1.1 0.4 9.8 1.9 0.0 0.5 404.0 0.1 0.0 0.3 16.0 5.2 17.6 1.0 27.6 64.2 0.7 0.0 0.4 6.1 CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5912.9;vagina: 1853.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2493.8;Club cells: 768.0;Kupffer cells: 579.4;monocytes: 1298.6;Squamous epithelial cells: 3020.6" "Cancer enhanced" "Detected in all" "cervical cancer: 227.7;head and neck cancer: 405.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "classical monocyte: 514.7;intermediate monocyte: 269.1;myeloid DC: 382.9;neutrophil: 245.6;non-classical monocyte: 161.7" "Group enriched" "Detected in all" 193 "dendritic cells: 382.9;granulocytes: 245.6;monocytes: 514.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 282.0;hTCEpi: 1218.6;THP-1: 789.0;U-698: 504.5;U-937: 250.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 28000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: AB_1078610" "unprognostic (5.22e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.07e-2)" "unprognostic (7.79e-3)" "prognostic favorable (5.86e-4)" "unprognostic (4.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (8.89e-2)" "unprognostic (3.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.99e-1)" 30.7 4.7 0.8 27.1 0.9 297.8 56.3 1.0 3.7 961.0 1.4 3.8 1.1 2.2 10.3 5912.9 4.6 7.2 5.9 0.8 1.0 2.4 38.9 26.0 25.1 1.5 0.9 21.1 3.7 0.8 5.0 19.0 1.3 19.7 3.6 0.3 996.1 9.6 4.6 369.1 5.8 6.3 1.1 20.4 30.3 1.3 1.4 46.5 2.7 2.8 941.0 39.1 1853.3 1.6 14.6 1.3 0.2 3.2 31.5 58.0 2.9 0.6 0.8 0.0 0.0 0.0 0.0 3.2 7.6 5.9 0.5 86.9 0.0 282.0 0.0 0.3 0.2 0.7 0.0 6.8 6.8 117.6 1.9 30.5 1218.6 2.9 119.1 0.0 0.0 1.5 0.8 29.9 0.5 0.8 0.2 108.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 141.3 0.0 0.0 14.1 7.5 10.4 0.1 1.6 789.0 0.5 1.7 19.7 0.2 0.9 0.0 1.7 504.5 26.4 250.3 0.3 8.8 514.7 16.4 0.6 269.1 1.5 1.5 0.7 0.6 382.9 0.5 0.5 0.7 245.6 1.9 161.7 6.9 1.0 283.2 0.8 0.9 1.0 3.7 0.8 1.0 1.5 0.9 1.3 1.1 1.4 1.6 1.1 6.4 19.8 0.0 5.0 83.5 136.5 2493.8 117.8 0.0 7.1 119.8 0.2 2.8 768.0 0.0 0.0 230.6 7.4 3.9 0.0 2.1 0.4 0.3 0.4 3.0 0.0 3.8 0.1 22.1 17.8 13.6 12.8 0.3 13.9 0.1 6.1 96.0 134.5 0.0 0.1 0.5 179.0 579.4 90.6 2.4 10.2 243.7 8.8 0.0 1298.6 0.0 20.6 0.5 0.2 46.2 1.5 3.8 2.8 30.2 0.0 0.7 115.7 0.0 32.9 8.8 24.3 0.1 0.5 3020.6 205.0 334.2 4.9 26.1 2.0 134.1 CSTB "CST6, EPM1, PME, STFB" ENSG00000160213 "Cystatin B" P04080 21 43772511-43776330 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "esophagus: 11304.7" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 5910.7;Club cells: 4352.8;Hofbauer cells: 2827.7;Squamous epithelial cells: 4910.2;Urothelial cells: 3198.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 2798.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017380, CAB047320, HPA058557" Enhanced Supported Nucleoli,Cytosol NA NA 8700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoli "CAB047320: , HPA017380: AB_1847414, HPA058557: AB_2683755" "unprognostic (1.69e-1)" "unprognostic (3.35e-1)" "unprognostic (2.09e-1)" "unprognostic (3.05e-2)" "unprognostic (3.05e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (6.66e-5)" "unprognostic (1.90e-1)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (1.27e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (3.63e-1)" "unprognostic (4.88e-1)" "unprognostic (4.24e-2)" "unprognostic (1.24e-1)" 224.3 165.6 254.1 141.6 253.6 73.8 161.9 255.4 314.6 585.8 275.2 243.8 122.9 90.1 175.0 11304.7 154.1 150.7 192.2 252.8 263.0 144.7 189.4 290.1 176.4 258.4 257.8 136.1 116.2 154.4 70.1 132.1 259.6 137.3 194.7 78.9 738.3 138.6 100.1 256.9 135.6 110.4 257.5 125.8 249.9 71.7 262.8 268.2 147.9 197.4 1484.9 611.8 1001.9 262.9 1573.6 495.5 146.3 188.1 874.5 742.6 379.6 310.1 431.0 230.7 230.6 401.6 868.6 123.0 245.8 570.1 1814.0 260.5 384.4 405.7 153.5 529.0 388.4 332.4 385.3 473.8 753.0 85.5 267.1 754.5 439.6 621.2 314.7 389.3 331.2 111.8 276.9 681.1 359.7 431.4 100.1 267.6 336.0 1052.6 791.5 169.7 80.5 1472.0 669.1 2798.2 141.8 121.6 420.2 229.2 928.8 75.7 210.4 214.0 426.3 347.7 162.7 305.5 211.8 148.5 347.4 251.1 1432.5 430.2 242.3 390.1 505.5 313.1 242.9 840.3 224.5 198.5 315.4 255.4 766.1 172.7 221.0 217.6 445.6 152.4 1322.9 93.4 406.9 475.2 254.1 253.6 255.4 314.6 252.8 263.0 258.4 257.8 259.6 257.5 262.8 262.9 210.1 176.3 298.4 43.4 140.5 385.3 460.6 5910.7 191.2 69.8 317.8 345.1 105.7 268.8 4352.8 415.6 35.5 310.4 126.5 803.9 538.1 588.4 10.4 388.8 205.1 307.8 239.3 61.4 17.0 488.2 1199.4 238.6 297.7 458.8 228.2 131.5 250.6 464.5 2827.7 67.3 18.4 308.6 1462.8 483.4 1256.2 40.8 381.1 806.9 471.4 24.4 915.9 160.6 255.4 11.1 32.4 810.9 735.6 330.2 167.7 674.3 524.9 469.9 1997.3 72.9 118.3 86.5 320.0 33.7 111.7 4910.2 596.0 402.5 202.8 170.9 367.2 3198.3 CTAG1A "ESO1, LAGE2A" ENSG00000268651 "Cancer/testis antigen 1A" P78358 X 154585133-154586816 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 67 "testis: 8.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 173 "U-266/70: 749.2;U-266/84: 332.1" CAB013061 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "CAB013061: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 749.2 332.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CTAG1B "CT6.1, CTAG, CTAG1, ESO1, LAGE2A, LAGE2B, NY-ESO-1" ENSG00000184033 "Cancer/testis antigen 1B" P78358 X 154617609-154619282 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "testis: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-266/70: 671.4" CAB015453 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "CAB015453: AB_784921" 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 7.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 671.4 41.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.7 0.2 0.2 0.3 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CTAG2 "CAMEL, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE-1a, LAGE-1b, LAGE1, MGC138724, MGC3803" ENSG00000126890 "Cancer/testis antigen 2" O75638 X 154651972-154653579 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 5.4;testis: 10.4" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 77.3" "Cancer enhanced" "Detected in many" "melanoma: 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 104.1;K-562: 140.6;OE19: 203.6;RPMI-8226: 311.3;SK-BR-3: 195.4;U-266/84: 356.9" "HPA071467, HPA076586" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA071467: AB_2686402, HPA076586: " "prognostic unfavorable (2.35e-4)" "unprognostic (3.87e-1)" "unprognostic (1.00e-1)" "unprognostic (1.25e-2)" 0.3 0.8 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.8 1.5 0.0 5.4 0.0 0.0 3.4 0.7 0.3 0.0 0.1 0.0 0.5 2.0 0.0 0.3 2.6 0.1 0.3 0.0 0.0 0.1 0.0 3.3 0.4 0.2 0.0 0.0 0.4 0.5 10.4 0.0 3.0 0.1 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 104.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.6 2.9 0.0 0.0 0.2 0.0 0.0 203.6 0.0 0.0 0.0 311.3 0.0 0.0 0.4 0.0 0.0 195.4 0.3 0.0 0.2 0.6 0.3 6.3 0.2 0.7 0.2 2.6 356.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.2 0.0 2.1 0.0 0.0 1.2 0.9 0.0 3.9 0.0 0.2 0.0 1.8 0.2 0.0 0.0 0.5 0.0 11.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 3.1 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 3.7 1.2 0.5 0.0 0.0 0.6 18.5 77.3 0.0 0.0 1.1 0.1 0.0 0.0 0.0 CTCF "CFAP108, FAP108" ENSG00000102974 "CCCTC-binding factor" P49711 16 67562467-67639177 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Chromosome partition, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004122, CAB062550, CAB068181, CAB068182" Supported Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB062550: AB_2665624, CAB068181: AB_2665625, CAB068182: AB_2665626, HPA004122: AB_2667139" "unprognostic (2.70e-1)" "unprognostic (4.21e-2)" "unprognostic (3.41e-2)" "unprognostic (4.70e-2)" "unprognostic (4.41e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.71e-2)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.36e-2)" "unprognostic (1.99e-2)" "prognostic favorable (4.06e-4)" "unprognostic (3.47e-1)" "unprognostic (5.99e-2)" "unprognostic (4.58e-2)" "unprognostic (1.11e-2)" 17.3 14.5 10.6 20.6 12.2 34.6 17.5 17.4 12.7 21.3 7.4 18.9 15.9 20.8 13.8 20.2 19.9 14.6 15.9 10.7 11.9 18.4 18.7 16.4 29.0 10.3 10.2 22.3 18.4 28.3 12.9 20.4 10.3 17.2 21.6 18.4 17.1 17.7 30.5 23.3 19.4 20.3 9.0 22.7 18.3 10.5 10.2 69.6 19.3 28.4 35.4 19.7 20.0 16.2 34.6 51.2 66.9 26.7 29.9 25.5 54.2 32.4 33.6 45.9 43.5 42.3 34.5 106.6 26.0 27.7 26.2 43.8 65.3 35.7 51.5 38.5 44.0 63.9 28.5 49.3 20.4 73.7 59.7 20.8 42.5 34.6 38.2 27.5 35.5 83.1 57.7 43.3 38.6 66.7 156.8 27.4 58.3 38.7 34.5 113.5 54.9 58.7 28.2 48.7 57.0 40.0 57.3 33.2 27.9 35.2 41.0 45.3 33.8 39.3 41.3 30.5 35.7 38.6 52.6 151.2 23.1 43.1 43.1 6.8 2.3 3.4 4.3 2.4 4.1 5.5 4.8 3.5 2.1 7.4 3.8 4.4 6.8 3.5 4.8 5.6 3.9 1.4 10.6 12.2 17.4 12.7 10.7 11.9 10.3 10.2 10.3 9.0 10.2 16.2 38.0 22.4 29.8 19.9 50.4 22.3 24.3 11.4 35.3 35.5 35.6 33.9 32.6 27.1 28.1 23.9 8.4 27.4 54.0 29.2 19.6 31.3 2.1 29.8 43.9 37.3 31.2 52.6 23.0 33.6 33.7 29.9 27.0 40.2 19.6 39.1 23.9 24.0 24.0 45.4 24.2 26.4 16.2 26.7 12.6 3.6 24.8 31.1 12.4 32.8 29.2 32.3 49.4 17.1 32.8 32.5 16.5 28.6 62.6 35.6 18.8 24.5 16.7 27.6 19.7 38.6 41.4 18.4 27.3 38.8 24.7 29.6 47.9 32.6 23.8 30.0 CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 539.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane" NA NA 2000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.54e-4)" "unprognostic (1.61e-1)" "unprognostic (9.55e-2)" "unprognostic (1.05e-2)" "unprognostic (3.20e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-2)" "unprognostic (1.88e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (9.79e-2)" 130.8 112.2 106.7 98.7 85.3 162.4 194.3 147.8 87.5 179.4 94.7 141.2 136.9 149.4 84.4 113.7 131.0 121.8 109.9 88.1 105.3 106.5 147.9 132.9 81.9 101.3 112.9 173.9 93.3 137.2 84.7 200.0 94.0 132.3 134.5 88.8 110.9 126.3 87.3 99.0 142.9 178.4 104.9 92.5 81.8 59.5 129.4 95.6 140.6 89.9 99.5 158.3 109.3 108.4 161.6 210.0 423.6 242.8 226.9 184.7 333.8 179.6 249.7 288.2 284.3 146.3 224.0 131.7 157.8 314.1 129.0 119.6 315.8 510.0 306.2 123.3 215.7 215.5 261.0 523.7 169.5 121.8 99.1 271.6 226.7 345.5 208.7 235.7 258.1 63.0 153.7 80.3 324.1 161.8 87.3 68.3 397.2 211.0 159.3 64.9 281.9 88.3 177.9 494.8 102.9 172.4 296.2 147.1 809.4 509.8 242.1 248.6 340.8 217.1 163.6 139.3 264.0 50.7 82.7 138.4 221.5 150.5 369.7 4.7 7.3 6.4 9.2 12.3 10.9 7.7 8.6 10.1 11.8 8.0 8.6 9.4 6.6 9.6 12.6 10.0 10.8 5.6 106.7 85.3 147.8 87.5 88.1 105.3 101.3 112.9 94.0 104.9 129.4 108.4 171.7 137.8 179.5 58.1 71.7 213.5 130.1 75.3 116.1 40.7 232.5 168.1 84.7 90.1 119.2 62.5 33.3 318.9 99.0 251.6 35.2 132.2 11.0 90.3 125.9 187.3 93.8 43.8 50.9 78.5 115.6 116.8 53.0 95.5 116.6 137.0 139.2 172.5 115.1 13.5 82.4 145.9 42.7 154.6 228.1 9.5 59.7 161.1 202.7 124.6 98.3 89.2 49.4 70.9 62.9 139.8 249.5 86.9 55.5 128.3 160.3 93.2 96.1 62.0 46.0 175.6 137.3 78.4 40.1 70.9 174.9 539.5 77.0 245.6 189.6 127.9 CTNNBL1 "C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L" ENSG00000132792 "Catenin beta like 1" Q8WYA6 20 37693955-37872129 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 372.9;granulocytes: 263.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 308.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004742, HPA027906, HPA027907" Approved Enhanced Nucleoplasm,Centrosome,Cytosol No No "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Centrosome, Cytosol" "HPA004742: AB_1847323, HPA027906: , HPA027907: AB_10601362" "unprognostic (2.81e-1)" "unprognostic (3.42e-1)" "unprognostic (8.80e-2)" "unprognostic (1.88e-3)" "unprognostic (1.93e-1)" "unprognostic (2.55e-2)" "unprognostic (1.44e-1)" "unprognostic (5.11e-2)" "unprognostic (1.02e-1)" "unprognostic (3.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-3)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (2.81e-1)" "unprognostic (5.31e-2)" 26.9 16.8 20.9 27.3 22.8 41.8 23.8 21.6 24.8 23.7 23.4 31.8 21.7 27.7 31.1 23.4 25.3 19.8 32.3 22.0 22.4 22.9 46.8 25.3 39.3 22.8 22.3 27.1 17.3 19.7 18.2 22.1 21.7 23.4 23.1 18.8 18.5 30.6 33.3 25.3 25.1 30.6 21.6 54.0 34.8 43.3 22.1 40.1 17.1 20.9 41.2 25.8 20.4 23.6 66.7 60.3 56.7 44.6 40.3 32.8 89.2 41.9 43.7 98.0 86.0 224.8 52.4 73.9 59.6 42.7 94.4 69.8 77.1 98.6 105.3 36.1 38.0 243.0 33.2 110.2 41.8 77.4 308.0 35.1 58.9 55.6 54.8 34.1 59.8 103.8 66.8 29.6 53.5 54.9 127.0 101.4 51.4 74.9 85.8 87.9 109.1 56.3 42.9 55.0 45.1 53.6 72.5 102.3 75.4 52.3 50.6 61.1 44.5 97.4 58.0 64.9 68.8 34.1 46.6 85.5 68.5 48.6 52.7 267.9 77.7 103.3 51.0 103.0 49.1 88.9 49.9 53.8 110.3 83.4 49.8 53.6 16.9 79.9 109.6 86.9 66.2 71.3 20.9 22.8 21.6 24.8 22.0 22.4 22.8 22.3 21.7 21.6 22.1 23.6 28.6 28.9 26.4 21.2 40.0 22.8 32.9 40.7 13.1 26.1 13.0 13.2 39.8 17.2 34.1 18.4 18.8 147.8 40.4 21.1 37.2 34.8 372.9 24.2 24.9 32.5 20.9 43.7 31.6 34.7 69.4 28.7 48.4 21.6 263.6 34.4 44.3 45.2 49.3 18.5 35.6 27.3 42.7 36.0 35.5 131.2 34.2 44.5 26.6 14.0 89.8 32.1 40.2 30.7 39.8 31.9 21.5 33.4 21.6 22.3 34.7 43.1 26.1 25.8 19.7 25.4 48.0 79.4 45.2 10.7 22.4 52.9 38.8 23.7 24.2 20.6 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1475.9;Hofbauer cells: 3763.5;Macrophages: 1512.6;Proximal enterocytes: 1699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 2596.6;hTERT-RPE1: 2780.1;SK-BR-3: 2488.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 318.6 734.6 147.0 204.9 181.9 499.0 244.0 186.0 156.5 270.8 672.7 298.0 387.6 170.7 82.8 319.4 171.6 438.4 444.1 187.8 223.6 691.6 464.8 539.6 241.0 247.6 206.6 130.7 284.8 137.3 131.5 180.7 228.6 138.2 153.4 48.3 422.1 231.7 590.3 340.9 398.3 105.0 188.9 442.0 287.2 88.9 334.4 78.1 182.1 178.2 123.1 296.4 307.5 367.1 204.6 578.9 51.4 246.2 586.5 206.3 112.1 149.4 362.2 161.8 182.8 147.5 2596.6 49.2 376.8 285.8 1265.6 1072.2 63.7 142.6 35.8 206.7 222.9 70.4 92.5 196.5 736.2 171.4 787.7 350.9 621.6 82.5 136.9 2780.1 128.2 62.1 89.2 267.6 263.3 832.6 47.0 110.9 153.1 719.7 247.9 62.5 72.5 191.2 586.6 610.8 84.2 94.8 173.3 2488.5 535.0 68.6 1022.8 232.6 170.3 556.8 92.9 79.0 216.7 432.0 382.3 26.8 867.7 468.6 509.6 211.2 578.7 170.1 156.5 309.9 90.6 28.8 72.1 110.3 144.5 18.8 82.5 107.4 319.5 192.3 265.2 120.3 89.2 489.1 147.0 181.9 186.0 156.5 187.8 223.6 247.6 206.6 228.6 188.9 334.4 367.1 139.3 112.2 228.6 48.3 62.8 72.0 223.5 473.2 71.7 168.6 108.9 113.8 251.9 314.5 459.5 548.1 110.5 211.7 156.1 1475.9 109.5 911.4 3.3 118.1 67.4 128.3 159.6 132.6 18.3 370.1 165.0 157.0 237.5 203.4 474.3 119.4 695.7 678.9 3763.5 264.2 25.2 418.2 498.5 1187.8 67.5 14.6 108.4 1512.6 227.7 20.6 382.6 179.0 256.4 27.2 42.2 392.3 832.5 128.2 122.5 111.7 1699.4 311.8 270.3 102.1 111.7 70.7 135.2 26.6 63.5 141.2 82.1 471.3 155.0 96.0 399.1 357.8 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Cell line enhanced" "Detected in many" "A-431: 450.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Golgi apparatus, Vesicles" "CAB011235: , HPA057242: AB_2683379" "unprognostic (6.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-1)" "unprognostic (3.13e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (2.19e-6)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.10e-2)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (6.97e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (1.94e-1)" 91.7 142.5 28.3 15.6 30.0 4.9 82.9 29.7 32.3 112.3 28.5 84.9 28.4 117.8 18.7 131.6 85.0 35.1 106.9 27.7 28.2 109.6 66.9 74.8 9.0 33.2 30.8 112.9 79.5 18.1 94.1 23.9 30.9 101.6 23.8 8.4 92.9 27.0 65.7 104.4 70.9 31.8 29.5 53.3 92.2 62.0 30.3 8.7 89.5 14.5 12.7 88.1 101.2 32.5 450.2 97.2 32.0 37.2 53.2 81.9 52.5 93.8 92.5 80.7 63.4 129.5 110.3 17.5 90.6 121.1 86.3 97.3 38.6 98.7 58.7 35.5 39.1 1.7 73.6 61.1 113.9 0.4 22.6 116.6 68.0 89.4 50.2 84.4 68.8 0.5 51.3 3.3 80.9 122.9 0.9 6.4 35.0 163.4 58.6 0.2 39.3 14.3 90.5 143.7 26.3 44.9 68.3 93.2 158.0 57.2 75.8 1.9 86.8 70.8 45.3 111.2 63.6 7.4 5.2 1.0 141.1 0.4 98.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 2.1 0.0 0.1 0.4 0.0 6.8 28.3 30.0 29.7 32.3 27.7 28.2 33.2 30.8 30.9 29.5 30.3 32.5 95.3 44.8 51.8 61.7 4.0 151.9 102.8 85.8 46.1 39.4 81.0 57.9 64.1 80.1 95.4 134.3 18.8 83.8 1.6 224.4 64.6 146.5 12.4 86.4 84.8 89.9 74.4 18.9 93.4 221.5 95.6 89.1 76.0 116.1 6.3 117.7 78.9 44.1 10.4 38.7 65.4 123.8 57.0 8.9 34.1 26.1 103.2 38.6 122.7 28.1 5.9 42.5 0.0 40.2 145.8 260.6 177.8 98.9 3.1 153.5 108.4 164.3 89.4 32.5 59.2 61.0 87.5 32.0 47.0 76.7 174.9 106.3 5.4 91.4 111.9 258.1 CUL1 ENSG00000055130 "Cullin 1" Q13616 7 148697914-148801110 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 466.3;Late spermatids: 567.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002676, HPA064584" Supported Supported Nucleoplasm,Nucleoli NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Nucleoli "CAB002676: , HPA064584: AB_2685294" "unprognostic (3.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-1)" "unprognostic (1.19e-1)" "unprognostic (5.06e-3)" "unprognostic (9.45e-2)" "unprognostic (1.41e-2)" "unprognostic (8.23e-2)" "unprognostic (2.40e-2)" "unprognostic (3.65e-2)" "unprognostic (3.40e-2)" "unprognostic (2.84e-2)" "unprognostic (2.18e-2)" "unprognostic (3.88e-2)" "unprognostic (1.48e-1)" "unprognostic (2.40e-1)" "unprognostic (7.24e-3)" 33.2 27.3 19.6 29.4 20.9 15.5 30.2 20.4 26.5 28.1 22.2 38.9 23.0 29.8 28.8 30.6 29.4 23.2 35.9 22.1 23.0 21.6 45.1 26.3 39.0 20.4 21.2 30.9 20.6 36.3 25.6 32.7 20.4 27.3 24.5 52.1 26.1 30.1 88.8 28.8 27.3 32.2 21.8 30.0 29.7 95.1 21.3 30.3 27.4 74.6 35.6 34.9 26.6 21.7 79.9 61.6 59.5 93.6 46.6 51.6 72.8 64.8 77.7 65.8 61.4 64.5 53.9 109.6 49.5 65.9 104.4 52.5 87.0 59.9 76.4 72.8 71.9 65.2 39.6 64.5 50.5 74.8 58.9 40.0 58.5 45.9 46.0 59.9 71.3 52.8 100.8 78.2 72.2 76.4 64.1 81.0 111.6 68.6 58.8 78.7 52.3 106.3 54.2 55.4 83.3 61.0 74.5 92.3 51.4 69.9 29.0 57.5 56.6 44.1 15.4 87.7 75.8 70.4 54.2 96.7 94.3 82.5 66.2 15.5 17.0 14.1 16.5 18.3 21.8 17.3 18.9 21.2 26.6 15.0 22.4 18.5 1.4 27.9 18.5 6.7 18.5 20.0 19.6 20.9 20.4 26.5 22.1 23.0 20.4 21.2 20.4 21.8 21.3 21.7 24.0 35.3 40.9 41.4 26.0 27.9 31.1 19.5 22.2 33.4 13.8 17.5 29.2 12.8 32.2 9.2 29.2 66.6 19.1 12.0 17.6 28.1 466.3 20.4 23.4 25.1 15.6 23.1 76.3 26.2 77.1 29.9 19.4 21.9 23.4 31.6 18.5 41.5 29.8 21.9 89.5 19.7 22.4 18.5 16.8 567.7 21.8 25.7 28.4 60.9 51.7 32.7 37.0 52.8 74.3 28.5 15.0 30.5 25.3 29.8 11.7 13.5 33.6 48.9 32.9 30.3 38.9 59.6 34.0 20.6 25.4 73.2 26.5 24.1 18.8 21.7 CUL2 ENSG00000108094 "Cullin 2" Q13617 10 35008551-35090642 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 319.6;Late spermatids: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002677, HPA024578" Approved Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB002677: , HPA024578: AB_1847338" "unprognostic (8.11e-3)" "unprognostic (1.12e-1)" "unprognostic (9.77e-2)" "unprognostic (1.17e-2)" "unprognostic (1.53e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (8.24e-6)" "unprognostic (2.18e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (4.70e-2)" "unprognostic (6.94e-2)" "prognostic unfavorable (9.32e-5)" "unprognostic (2.26e-2)" "unprognostic (2.31e-1)" "unprognostic (3.70e-1)" "unprognostic (2.29e-1)" 15.3 13.3 10.5 16.2 11.7 20.1 15.5 11.9 13.1 13.0 9.8 14.7 14.5 14.8 10.4 16.8 11.0 12.0 19.2 12.2 12.2 14.3 21.0 13.4 19.8 10.8 11.2 12.7 13.4 22.1 8.8 18.8 11.4 15.3 15.2 13.2 11.5 15.7 45.2 13.4 13.9 19.1 11.5 15.0 14.0 35.8 12.3 18.2 16.2 37.6 20.8 17.0 10.1 12.2 50.4 29.2 37.7 32.5 42.0 46.0 39.8 57.8 32.1 56.1 56.2 38.7 47.0 39.9 31.0 61.6 41.1 45.3 55.4 53.4 63.9 46.9 35.9 51.8 29.0 34.8 46.0 28.6 32.6 44.5 43.7 61.6 21.4 43.3 63.6 41.5 60.5 35.2 62.2 34.4 47.7 15.9 13.8 34.4 117.3 39.4 61.0 25.0 51.3 38.9 18.4 24.4 32.4 40.3 47.0 41.6 30.7 32.4 58.6 34.5 38.3 59.6 38.4 14.7 21.2 47.4 66.4 63.2 24.8 12.8 9.9 11.6 12.3 14.9 17.4 10.9 13.5 14.6 12.6 12.6 16.1 15.2 4.8 13.3 15.3 5.7 17.8 8.5 10.5 11.7 11.9 13.1 12.2 12.2 10.8 11.2 11.4 11.5 12.3 12.2 24.8 22.4 12.6 21.9 23.0 12.0 8.6 13.1 9.6 13.1 12.0 12.4 26.4 5.7 20.7 9.2 10.4 24.7 27.8 9.9 15.6 18.4 319.6 17.5 25.4 22.3 10.7 9.4 39.7 17.8 20.1 15.7 9.2 20.5 20.3 19.2 16.4 18.2 20.1 23.5 35.6 10.6 14.2 17.2 12.3 181.0 14.0 20.3 10.6 27.2 23.0 16.0 27.8 30.7 41.7 17.5 6.9 11.7 17.3 8.3 15.2 15.0 19.9 13.7 0.0 16.1 26.9 40.1 32.8 14.4 13.1 37.1 25.3 23.0 13.1 9.9 CUL4B ENSG00000158290 "Cullin 4B" Q13620 X 120505920-120604074 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 106.9;Late spermatids: 169.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003046, HPA011880, CAB017786, HPA058979" Enhanced Enhanced Nucleoplasm NA NA 18000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "CAB017786: , HPA003046: , HPA011880: AB_1847340, HPA058979: AB_2683868" "unprognostic (2.34e-2)" "unprognostic (2.74e-2)" "unprognostic (2.69e-2)" "unprognostic (7.73e-3)" "unprognostic (9.66e-2)" "unprognostic (3.91e-1)" "unprognostic (3.88e-3)" "unprognostic (8.99e-2)" "unprognostic (8.12e-3)" "unprognostic (3.20e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-1)" "unprognostic (2.87e-3)" "unprognostic (3.83e-2)" "unprognostic (1.35e-1)" "unprognostic (6.82e-2)" "unprognostic (2.84e-1)" 18.7 20.5 15.3 14.4 16.5 9.8 20.0 18.2 19.3 24.6 15.7 20.0 12.3 18.7 27.3 23.4 19.6 15.5 15.5 16.0 19.2 18.1 19.5 14.5 20.5 14.4 16.4 25.2 17.0 24.2 26.9 15.5 15.7 18.2 13.5 19.9 15.1 22.5 10.0 15.2 15.4 15.6 13.7 17.7 15.5 28.0 16.2 25.3 15.8 12.5 21.8 18.2 20.3 16.1 41.9 37.3 28.7 31.4 129.5 57.0 22.4 89.8 104.1 71.3 69.4 30.4 110.6 40.1 35.5 206.8 127.7 29.9 61.1 27.7 84.8 26.1 26.6 20.5 42.1 25.9 50.6 22.6 28.1 65.6 22.2 45.1 37.5 134.8 133.2 22.6 33.6 31.7 78.4 24.5 30.7 19.0 45.4 52.6 39.5 23.4 27.1 43.4 23.2 19.5 32.9 27.4 74.2 36.8 36.5 35.0 28.8 20.9 177.6 57.1 30.5 76.3 88.6 21.2 50.0 52.2 59.9 28.2 55.2 6.6 3.8 8.1 5.6 3.1 6.1 5.7 5.2 5.2 4.4 4.4 6.0 6.2 14.4 4.4 2.4 7.0 6.9 4.1 15.3 16.5 18.2 19.3 16.0 19.2 14.4 16.4 15.7 13.7 16.2 16.1 18.7 22.4 14.4 11.8 15.5 15.2 9.6 12.9 12.5 15.7 17.3 14.7 14.6 8.6 11.7 14.7 14.6 10.1 19.9 14.7 13.7 10.1 106.9 12.4 15.6 18.2 24.6 13.3 18.4 8.9 25.0 21.2 14.3 15.8 14.0 20.5 40.7 16.4 17.5 25.2 20.9 13.9 8.2 30.5 13.9 169.3 21.5 18.4 12.4 14.0 17.6 15.0 7.2 23.1 21.0 16.7 7.3 21.4 18.9 9.5 11.0 14.4 17.8 14.1 13.1 17.0 16.6 12.6 13.9 23.0 13.8 10.0 14.1 21.7 12.7 9.5 CUL5 VACM-1 ENSG00000166266 "Cullin 5" Q93034 11 108008898-108107761 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002185, CAB017787" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Cytosol" "CAB017787: , HPA002185: AB_1078587" "unprognostic (5.66e-2)" "unprognostic (6.58e-2)" "unprognostic (7.16e-3)" "unprognostic (1.30e-1)" "unprognostic (5.54e-2)" "unprognostic (1.62e-1)" "unprognostic (2.32e-2)" "unprognostic (2.80e-1)" "unprognostic (5.97e-3)" "unprognostic (1.78e-1)" "unprognostic (9.17e-2)" "unprognostic (1.77e-2)" "prognostic favorable (1.06e-5)" "unprognostic (3.83e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" 9.8 11.5 6.8 9.5 7.0 28.3 13.0 10.9 9.1 11.8 7.3 9.1 9.0 13.1 9.9 10.6 9.6 8.5 15.2 6.8 8.0 16.3 14.2 8.8 11.2 6.4 6.8 12.4 8.9 13.4 5.7 11.4 6.5 12.1 9.1 12.7 8.5 9.5 46.4 11.4 8.6 10.5 7.4 9.8 9.4 6.5 6.8 12.7 14.4 37.5 10.3 10.0 7.0 10.3 14.4 6.6 19.6 15.1 12.5 20.2 9.7 15.0 16.3 13.4 15.0 21.3 16.5 20.1 27.3 18.8 14.0 18.0 18.4 12.3 19.4 13.2 11.1 18.9 6.2 15.7 21.1 21.8 14.9 15.8 16.1 14.1 18.6 17.5 18.7 16.2 25.0 7.2 21.4 7.9 20.9 18.1 10.3 18.4 11.6 15.0 14.6 21.8 16.4 21.2 13.9 19.6 20.4 21.1 12.3 12.0 31.1 17.0 19.7 24.6 11.4 17.6 16.2 7.2 6.2 26.5 9.6 24.0 16.0 1.2 2.3 1.6 2.1 2.1 2.0 1.7 2.1 1.9 2.3 2.2 2.3 2.3 0.4 1.6 2.2 2.5 1.7 1.3 6.8 7.0 10.9 9.1 6.8 8.0 6.4 6.8 6.5 7.4 6.8 10.3 50.2 57.7 42.5 66.3 49.0 29.8 29.3 26.0 44.3 52.7 35.1 25.7 111.9 37.1 39.2 31.3 66.7 37.6 49.2 21.8 50.9 29.6 6.0 45.4 48.7 41.3 17.6 34.3 84.9 23.5 23.6 42.6 33.1 40.9 43.1 42.8 40.0 54.8 27.1 55.5 83.8 28.7 22.4 41.6 20.3 8.0 30.7 41.2 14.2 61.8 51.7 31.5 30.9 74.4 101.7 29.1 29.0 38.0 48.4 36.6 27.9 76.7 36.6 59.4 19.7 56.0 53.1 35.5 44.0 43.9 30.3 35.8 38.8 48.0 30.3 32.9 CUX1 "CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6" ENSG00000257923 "Cut like homeobox 1" "P39880, Q13948" 7 101815904-102283958 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Transport" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 35.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003277, HPA003317" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Golgi apparatus" "HPA003277: AB_10601804, HPA003317: AB_2666891" "unprognostic (5.86e-2)" "unprognostic (5.39e-3)" "unprognostic (9.62e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (7.51e-4)" "unprognostic (5.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (2.89e-3)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "prognostic favorable (5.72e-7)" "unprognostic (1.12e-1)" "unprognostic (8.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.97e-1)" 30.5 18.0 23.8 24.8 33.6 33.4 17.9 54.0 48.2 35.5 28.0 40.5 33.7 60.9 16.9 32.6 35.3 31.7 82.8 21.5 23.3 40.0 23.2 33.1 19.4 30.8 27.5 46.9 63.3 46.0 24.6 23.1 27.4 30.7 25.3 19.2 36.1 23.2 45.5 24.0 37.3 40.8 26.2 16.9 35.3 9.6 29.3 34.7 49.4 38.8 20.6 32.4 24.8 30.5 41.8 44.0 30.3 37.7 24.1 49.3 18.4 41.1 43.0 17.0 10.9 26.2 26.2 53.6 64.2 40.8 31.3 33.4 19.4 32.9 10.1 25.9 21.8 18.8 32.8 22.2 63.7 24.7 9.9 34.6 65.9 13.1 29.5 48.7 22.3 34.0 44.5 44.2 16.3 85.9 80.8 30.1 12.3 64.0 45.4 52.6 25.1 64.4 27.6 46.5 27.7 82.6 35.8 88.4 35.4 25.1 17.4 29.0 33.5 71.2 47.8 54.4 23.7 28.8 14.5 114.7 65.8 22.3 50.8 3.3 13.9 2.3 3.1 13.4 3.0 2.9 2.3 3.1 10.8 2.4 2.2 3.1 7.0 4.5 35.0 18.2 2.2 8.4 23.8 33.6 54.0 48.2 21.5 23.3 30.8 27.5 27.4 26.2 29.3 30.5 33.7 99.3 60.5 78.4 35.3 26.3 30.9 30.9 33.6 67.2 23.9 17.1 110.5 31.5 40.3 40.5 68.8 54.6 59.6 69.2 9.8 34.4 9.5 50.6 165.2 42.1 42.5 50.0 129.0 24.0 55.5 51.8 62.2 85.0 12.0 97.8 37.5 36.1 32.8 53.8 116.2 48.7 38.7 70.2 42.5 9.4 41.3 75.4 17.8 139.6 65.2 47.7 32.0 96.0 117.5 34.1 50.2 60.9 46.0 55.5 42.9 64.5 37.9 57.3 26.3 105.2 56.6 13.5 14.4 39.9 43.3 88.0 25.7 34.7 46.0 43.8 CXCL1 "FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1" ENSG00000163739 "C-X-C motif chemokine ligand 1" P09341 4 73869393-73871308 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 102.2;lymphoid tissue: 196.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16674.3;Club cells: 7384.0;Ionocytes: 4146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 243 "neutrophil: 47.3" "Lineage enriched" "Detected in single" 243 "granulocytes: 47.3" "Group enriched" "Detected in many" 6 "BJ hTERT+: 748.4;EFO-21: 1906.7;RPTEC TERT1: 682.0" "Secreted to blood" NA NA 384000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "prognostic favorable (7.83e-4)" "prognostic unfavorable (7.23e-4)" "unprognostic (5.24e-3)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (5.45e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.17e-1)" "unprognostic (5.30e-2)" "unprognostic (7.41e-2)" "unprognostic (9.41e-2)" 38.0 6.2 4.3 49.0 4.9 41.6 3.8 3.6 8.1 102.2 4.8 14.6 10.6 2.3 0.1 38.7 14.9 25.7 28.3 3.5 3.7 18.7 10.2 45.2 2.4 4.0 3.7 2.4 25.7 0.4 2.0 5.1 4.3 18.7 16.0 0.4 23.7 9.5 1.7 2.2 26.9 3.0 4.1 196.6 9.1 0.2 5.4 2.9 1.9 1.9 23.6 75.5 25.5 4.2 3.7 4.4 0.0 0.0 4.4 11.7 0.0 20.6 748.4 17.7 18.8 0.2 13.4 0.0 1906.7 1.3 72.5 38.6 0.0 3.5 94.2 2.8 0.0 0.0 1.3 0.0 4.4 0.0 0.0 9.7 1.3 133.2 10.6 1.4 144.7 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 7.7 5.4 0.0 0.0 0.0 682.0 16.7 0.1 0.0 1.5 0.3 40.4 2.0 0.5 1.9 173.9 0.0 6.6 37.8 1.5 0.0 1.6 3.7 1.9 0.1 26.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 4.3 4.9 3.6 8.1 3.5 3.7 4.0 3.7 4.3 4.1 5.4 4.2 7.9 44.8 273.3 0.0 2.9 126.6 991.1 16674.3 131.5 0.0 61.3 42.9 4.1 413.2 7384.0 5.5 0.0 0.3 1.4 40.3 0.0 1073.2 0.0 152.2 21.5 106.7 635.7 0.0 0.0 42.5 0.7 449.0 20.9 199.0 15.8 1.4 3.9 2.1 26.7 0.0 0.0 31.1 4146.2 10.4 467.3 0.0 0.0 110.8 124.5 0.0 56.9 0.0 0.0 0.0 0.0 232.8 7.6 0.0 0.1 2062.0 19.6 3.1 1219.7 0.0 0.0 152.9 217.7 0.4 0.2 48.7 105.1 0.4 27.8 0.1 66.0 1251.3 CXCL10 "C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10" ENSG00000169245 "C-X-C motif chemokine ligand 10" P02778 4 76021118-76023497 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.7;Glandular and luminal cells: 23.5;Kupffer cells: 41.1;Langerhans cells: 21.4;Macrophages: 45.7;Plasma cells: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 21.5;intermediate monocyte: 52.4;non-classical monocyte: 36.9" "Lineage enriched" "Detected in many" 15 "monocytes: 52.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.1;BJ hTERT+ SV40 Large T+: 2.2;BJ hTERT+ SV40 Large T+ RasG12V: 2.2;GAMG: 5.1;RPMI-8226: 4.3;RT4: 2.4;THP-1: 3.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 253000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.94e-1)" "unprognostic (5.32e-2)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (7.59e-2)" "prognostic favorable (1.12e-5)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-2)" 4.0 5.9 1.4 95.5 1.5 1.2 20.7 0.9 2.6 13.2 1.2 10.7 11.2 7.1 0.7 8.0 4.1 10.6 4.4 1.2 1.0 7.8 29.0 35.1 68.0 7.4 1.2 3.0 0.9 17.1 2.1 10.3 10.8 43.9 15.9 0.4 20.1 1.8 1.2 2.0 11.2 15.8 3.4 20.3 19.2 3.0 2.6 35.2 3.7 1.1 17.3 45.1 3.7 1.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.1 2.2 2.2 0.2 0.1 2.0 0.2 0.0 5.1 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.3 0.1 2.4 0.0 0.0 0.0 0.4 1.3 0.0 0.1 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.6 0.0 0.0 21.5 0.0 0.0 52.4 0.0 1.4 0.3 0.0 3.5 0.1 0.0 0.0 1.1 0.0 36.9 0.0 0.0 7.6 1.4 1.5 0.9 2.6 1.2 1.0 7.4 1.2 10.8 3.4 2.6 1.5 3.8 0.0 2.2 0.0 2.2 0.9 9.4 52.7 0.6 0.0 2.6 7.0 0.3 1.5 2.8 0.0 0.0 0.1 0.0 2.7 0.0 5.9 2.6 12.5 10.9 8.0 0.0 0.0 0.0 0.0 0.0 6.9 3.1 23.5 1.3 0.0 0.0 0.1 17.3 0.0 0.0 1.0 10.2 41.1 21.4 4.0 0.3 45.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 11.4 6.4 2.6 1.3 0.0 0.0 1.3 12.4 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.9 1.4 CXCL13 "ANGIE, ANGIE2, BCA-1, BLC, BLR1L, SCYB13" ENSG00000156234 "C-X-C motif chemokine ligand 13" O43927 4 77511753-77611834 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 523.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 242.2;Breast myoepithelial cells: 72.4;Endometrial stromal cells: 101.0;monocytes: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA052613 Uncertain "Secreted to blood" NA NA 93700 "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" "HPA052613: AB_2681885" "unprognostic (5.25e-3)" "unprognostic (1.19e-2)" "prognostic favorable (9.12e-4)" "prognostic favorable (5.52e-4)" "unprognostic (1.53e-2)" "unprognostic (1.17e-3)" "unprognostic (1.49e-1)" "unprognostic (6.41e-3)" "unprognostic (9.82e-3)" "prognostic favorable (5.41e-4)" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (1.16e-10)" "unprognostic (2.04e-2)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (6.68e-3)" 2.6 0.4 0.1 127.7 0.4 0.1 15.4 0.4 0.3 1.4 0.1 13.3 1.9 3.6 1.6 2.4 0.8 5.8 1.2 0.1 0.1 0.6 28.5 2.9 523.1 1.1 0.1 0.7 0.3 0.2 3.1 0.6 0.1 27.3 16.5 0.2 8.5 1.4 0.0 0.6 68.5 1.2 0.4 338.6 34.9 1.5 0.1 16.2 2.4 0.0 441.3 30.6 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.1 0.1 1.1 0.1 0.1 0.4 0.1 0.2 0.9 0.0 0.5 1.3 0.3 0.1 15.8 3.9 0.0 0.0 242.2 72.4 0.0 1.5 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.6 101.0 1.7 0.0 10.7 1.9 0.2 0.3 6.3 0.5 1.8 1.3 0.0 3.6 21.3 10.2 0.0 3.9 0.0 0.0 3.4 0.0 0.0 0.0 0.9 0.0 1.9 38.8 0.0 0.0 1.0 0.4 0.1 0.0 0.0 0.2 3.8 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.3 7.8 0.0 0.1 4.5 CXCL2 "CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2" ENSG00000081041 "C-X-C motif chemokine ligand 2" P19875 4 74097040-74099196 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 509.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1668.3;Basal respiratory cells: 3166.0;Basal squamous epithelial cells: 1671.5;Langerhans cells: 2390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 1.1;non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 10 "monocytes: 1.1" "Cell line enriched" "Detected in many" 8 "GAMG: 430.9" "Secreted to blood" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "prognostic favorable (5.93e-5)" "prognostic unfavorable (1.41e-4)" "unprognostic (5.28e-3)" "unprognostic (1.36e-1)" "unprognostic (2.64e-3)" "unprognostic (1.27e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (6.72e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.07e-6)" "unprognostic (1.05e-2)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" 95.6 12.5 4.7 28.2 3.7 88.7 39.6 3.3 6.1 61.0 4.0 9.6 3.5 15.1 0.3 12.2 17.4 52.2 49.8 4.3 10.1 14.7 509.9 87.6 12.6 5.8 4.7 9.1 88.3 2.7 7.2 3.8 4.0 13.4 21.1 1.7 20.7 10.0 21.5 3.2 11.0 14.8 4.4 7.8 26.6 1.3 9.7 3.8 6.6 35.6 1.3 82.1 3.4 4.2 1.3 3.8 0.2 0.0 1.3 4.4 0.1 4.2 52.9 2.1 6.2 0.3 8.0 0.0 7.0 0.3 430.9 0.1 0.3 11.2 8.4 0.1 0.2 3.3 5.0 0.0 35.6 1.4 0.0 4.0 38.5 27.2 37.0 1.4 4.6 0.1 0.1 0.0 1.1 0.0 0.5 0.5 0.0 4.6 1.1 0.0 0.0 0.0 26.2 0.0 0.0 0.1 2.5 0.4 1.1 0.4 0.1 0.1 7.1 1.9 0.7 7.7 4.0 0.1 0.1 0.1 30.8 8.9 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 4.7 3.7 3.3 6.1 4.3 10.1 5.8 4.7 4.0 4.4 9.7 4.2 620.7 477.5 1668.3 1.0 15.0 415.5 336.3 3166.0 1671.5 0.0 762.9 283.3 22.9 469.0 957.6 9.2 0.0 3.3 17.9 91.4 0.0 858.1 1.1 489.8 149.1 677.8 132.1 34.7 0.0 603.6 3.1 488.7 206.9 1223.1 85.2 0.1 365.1 325.8 117.3 0.0 0.0 131.6 498.5 291.4 2390.3 0.8 15.8 926.0 277.5 0.0 50.7 0.6 0.0 0.0 0.0 282.5 14.6 0.0 35.3 342.6 57.8 1.1 194.1 0.3 72.3 131.8 288.7 1.1 5.0 440.3 227.7 2.2 36.3 0.6 128.5 119.1 CXCL5 "ENA-78, SCYB5" ENSG00000163735 "C-X-C motif chemokine ligand 5" P42830 4 73995642-73998677 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 35.9;salivary gland: 50.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 64.6;Ductal cells: 94.0;Macrophages: 222.6;Pancreatic endocrine cells: 245.4" "Group enriched" "Detected in many" 4 "pancreatic cancer: 56.2;stomach cancer: 74.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 191.9;EFO-21: 157.0;HSkMC: 111.4;hTEC/SVTERT24-B: 81.6;RPTEC TERT1: 603.6" HPA065474 Approved Approved Vesicles "Secreted to blood" NA NA 1110000 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA065474: AB_2685494" "unprognostic (5.56e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.43e-2)" "unprognostic (2.04e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.06e-2)" "unprognostic (3.04e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (7.99e-2)" "prognostic unfavorable (2.45e-5)" "unprognostic (3.72e-1)" "unprognostic (3.07e-1)" "unprognostic (2.72e-2)" "unprognostic (9.30e-2)" 2.1 0.2 1.5 35.9 0.9 1.2 3.2 0.6 8.8 7.7 0.4 0.7 0.8 0.2 0.0 0.1 0.2 4.8 0.6 0.8 2.6 0.2 1.3 10.0 6.3 1.4 2.1 0.0 0.5 0.0 0.1 0.2 3.1 1.3 0.3 0.0 50.2 0.5 0.1 0.0 2.1 0.2 1.1 2.1 8.5 0.4 5.7 0.6 0.0 0.2 0.6 8.4 0.0 0.7 0.1 191.9 0.7 0.0 0.3 6.9 0.0 3.5 2.9 1.5 3.0 0.6 1.6 0.0 157.0 0.1 34.0 0.4 0.0 0.0 17.6 0.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 111.4 0.0 81.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 603.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.5 0.0 1.0 0.0 0.1 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.0 1.5 0.9 0.6 8.8 0.8 2.6 1.4 2.1 3.1 1.1 5.7 0.7 0.2 3.2 0.0 0.0 0.0 0.9 0.7 64.6 0.0 0.0 8.0 4.4 1.2 15.7 33.2 0.0 0.0 0.0 0.1 1.3 0.0 94.0 0.7 0.7 0.1 1.8 0.0 0.0 0.3 1.4 0.1 3.6 15.3 1.2 0.0 0.0 0.7 0.0 0.5 0.0 0.3 0.7 4.1 0.3 30.4 0.3 0.0 222.6 0.0 1.0 2.1 0.0 0.0 0.0 0.1 245.4 0.0 0.0 0.3 3.1 0.0 0.1 4.3 0.0 0.0 0.6 4.0 0.1 0.6 0.0 0.3 0.0 0.3 0.0 1.1 2.0 CXCL8 "3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1" ENSG00000169429 "C-X-C motif chemokine ligand 8" P10145 4 73740541-73743716 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3301.3" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13262.1;Macrophages: 3685.4;Prostatic glandular cells: 8869.1;Urothelial cells: 13149.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 9 "cerebral cortex: 136.1" "Immune cell enriched" "Detected in some" 451 "neutrophil: 483.0" "Lineage enriched" "Detected in single" 788 "granulocytes: 483.0" "Group enriched" "Detected in many" 5 "BJ hTERT+: 4072.6;GAMG: 1080.2" "Not detected" "Not detected" HPA057179 Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 7260 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA057179: AB_2683362" "unprognostic (3.42e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (3.91e-3)" "unprognostic (8.49e-2)" "unprognostic (3.29e-2)" "unprognostic (3.03e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.37e-3)" "unprognostic (3.19e-1)" "unprognostic (4.46e-1)" "unprognostic (7.19e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.13e-6)" "unprognostic (4.73e-2)" "unprognostic (8.57e-2)" "unprognostic (1.64e-2)" "unprognostic (6.15e-2)" 67.9 13.5 1.8 209.9 2.8 3301.3 3.6 1.7 136.1 54.5 7.6 10.6 3.6 41.0 0.2 3.7 8.9 177.2 33.8 1.7 1.6 10.8 77.7 91.2 1.2 2.1 1.6 6.0 16.1 1.8 3.2 41.1 15.1 9.6 7.3 0.9 25.4 1.5 1.3 3.2 4.9 12.7 1.9 10.3 8.8 0.7 4.9 15.2 3.4 8.1 8.7 456.7 4.0 1.9 2.7 1.4 0.0 0.1 3.9 19.4 0.2 25.7 4072.6 35.9 117.0 0.2 13.0 0.2 547.6 1.3 1080.2 48.2 0.0 1.0 562.3 1.8 0.2 0.9 0.4 6.5 6.8 41.0 2.5 12.4 1.7 119.0 2.9 12.9 124.9 0.0 1.4 0.8 0.7 0.0 0.0 55.7 0.0 14.7 20.3 0.3 0.5 0.9 317.3 17.2 0.1 0.0 1.9 0.1 61.1 0.8 0.1 5.6 308.3 56.8 5.1 15.1 55.0 0.4 0.7 1.7 252.5 30.9 88.2 1.0 0.6 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 483.0 0.0 0.0 0.0 0.0 0.1 1.8 2.8 1.7 136.1 1.7 1.6 2.1 1.6 15.1 1.9 4.9 1.9 28.6 51.3 254.1 0.0 26.4 0.0 13262.1 0.0 164.4 0.5 40.2 15.4 23.8 127.2 426.5 0.0 0.0 4.3 17.7 14.4 0.0 1695.0 3.2 717.6 257.1 712.2 19.1 8.0 0.0 260.7 5.2 1475.1 54.0 1708.7 51.2 0.5 15.7 3.6 367.1 0.0 0.0 26.4 0.0 543.0 0.0 1.9 0.6 3685.4 0.0 0.0 1178.5 0.5 0.0 0.0 0.0 584.9 0.3 0.4 27.3 8869.1 0.9 1.0 178.6 1.1 39.5 44.3 263.0 0.3 2.5 124.9 0.0 21.3 138.8 0.0 18.5 13149.4 CXCL9 "CMK, crg-10, Humig, MIG, SCYB9" ENSG00000138755 "C-X-C motif chemokine ligand 9" Q07325 4 76001275-76007509 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 309.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.0;Hofbauer cells: 6.2;Kupffer cells: 10.3;Macrophages: 12.6;Spermatogonia: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "RPMI-8226: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 902000 "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "prognostic favorable (6.36e-4)" "unprognostic (6.86e-3)" "unprognostic (1.25e-2)" "prognostic favorable (2.07e-4)" "unprognostic (2.97e-1)" "unprognostic (3.78e-3)" "unprognostic (8.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.46e-2)" "prognostic favorable (8.06e-4)" "unprognostic (2.18e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.15e-6)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (1.57e-2)" "unprognostic (6.54e-2)" 5.5 2.0 0.1 65.1 0.2 0.2 17.5 0.1 0.6 4.9 0.3 10.2 3.0 4.8 0.7 5.3 2.8 8.5 5.9 0.1 0.1 8.7 19.1 31.8 309.9 1.8 0.2 3.8 1.4 1.5 1.0 1.7 1.6 3.7 25.3 0.0 19.0 0.7 1.5 2.9 6.0 3.2 0.3 31.2 17.5 6.0 0.2 32.8 7.1 2.5 30.6 11.1 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 1.8 0.2 1.6 0.3 0.2 0.3 3.4 0.0 1.7 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.2 0.4 0.0 0.2 1.3 0.1 1.1 2.1 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 5.0 1.8 6.2 0.0 0.0 0.0 0.0 10.3 3.6 1.3 0.6 12.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 3.5 1.7 8.0 0.0 0.3 0.1 0.5 0.0 0.1 0.4 CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.1;dendritic cells: 5.2;granulocytes: 2.5;NK-cells: 11.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1472.7" "Lineage enriched" "Detected in many" 62 "granulocytes: 1472.7" "Cell line enriched" "Detected in single" 26 "HMC-1: 5.8" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" 13.2 0.5 0.3 25.1 0.5 9.5 0.4 0.3 1.7 0.7 0.5 0.4 0.2 0.2 0.0 1.6 2.9 4.1 1.8 0.3 0.3 0.5 2.0 9.7 0.3 0.4 0.4 0.1 1.5 0.3 0.2 2.6 1.2 0.3 0.2 0.0 0.5 0.1 0.4 0.3 0.6 1.8 0.3 40.5 0.9 0.2 0.5 1.8 0.4 12.0 0.6 5.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 2.3 2.9 23.7 0.8 0.3 0.2 2.1 6.1 0.7 0.1 0.4 8.7 1472.7 1.5 3.2 0.9 0.3 8.3 0.3 0.5 0.3 1.7 0.3 0.3 0.4 0.4 1.2 0.3 0.5 0.3 0.0 0.0 5.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.7 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42617840-42649392 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 830.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" 404.4 310.5 147.1 87.4 152.9 82.7 272.2 145.7 189.9 237.3 115.0 192.4 94.8 248.4 58.8 152.4 174.0 139.5 374.3 138.7 163.9 182.9 279.4 201.3 76.3 194.7 174.2 218.3 89.1 62.0 137.4 107.8 169.9 181.4 74.9 27.3 149.8 239.3 203.0 233.6 138.1 200.2 154.8 101.4 182.0 142.7 156.7 54.0 157.8 140.5 72.3 216.7 210.0 160.2 125.5 78.6 126.6 78.6 830.9 654.7 74.4 359.2 330.0 262.2 232.4 104.0 95.6 58.8 156.6 668.8 113.8 112.4 85.3 178.0 133.7 63.9 187.3 83.6 127.3 202.4 211.0 118.4 149.5 397.4 138.1 188.9 124.5 190.8 220.0 74.0 73.5 296.3 361.9 137.9 116.8 108.4 51.0 129.2 142.7 84.9 153.8 131.3 202.0 90.6 56.1 73.2 118.6 113.2 134.0 92.6 90.6 112.0 340.9 282.0 175.3 192.3 137.9 78.3 91.2 72.4 328.8 67.8 237.9 126.3 104.0 300.3 75.9 135.3 76.6 110.1 72.8 83.9 154.0 102.7 50.8 54.0 53.8 63.5 176.7 140.8 95.0 86.4 147.1 152.9 145.7 189.9 138.7 163.9 194.7 174.2 169.9 154.8 156.7 160.2 238.5 86.6 62.2 17.0 51.7 110.1 95.5 184.8 27.3 16.7 52.3 73.2 106.4 105.8 100.9 60.7 4.2 110.0 37.0 90.5 49.0 216.4 4.8 51.4 82.9 161.5 83.7 113.9 12.3 107.0 199.3 183.4 38.2 65.4 62.8 57.8 180.2 230.4 108.3 16.8 16.1 45.8 142.4 50.6 112.0 17.0 253.9 67.7 176.1 25.3 112.5 91.0 33.0 7.1 26.4 156.8 85.6 280.6 36.7 82.3 116.9 110.8 53.3 18.4 190.7 62.5 202.5 23.8 45.5 57.5 112.7 117.9 43.0 233.1 55.2 96.4 CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 94.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 136.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011713, HPA050095" Approved Supported "Nucleoplasm,Centriolar satellite" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" Nucleoplasm "CAB011713: AB_731794, HPA050095: AB_2681013" "unprognostic (9.83e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "unprognostic (2.83e-2)" "unprognostic (3.84e-1)" "unprognostic (5.06e-2)" "unprognostic (3.87e-2)" "unprognostic (3.24e-2)" "unprognostic (9.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-2)" "unprognostic (6.83e-2)" "unprognostic (8.42e-2)" 14.3 22.0 23.9 38.8 23.5 94.3 13.6 17.9 18.2 13.0 22.3 16.3 16.1 15.1 12.1 23.3 11.0 20.5 20.1 17.3 23.3 14.2 21.0 21.5 53.4 21.3 27.8 15.4 15.2 23.0 15.4 15.4 23.6 16.3 19.3 22.0 18.9 16.0 34.3 15.2 16.2 16.8 21.6 39.0 19.9 38.3 32.7 35.6 24.9 20.5 48.4 24.1 12.9 24.2 26.9 8.3 9.4 10.6 14.3 21.0 8.7 39.1 56.7 39.9 23.4 6.9 12.5 30.7 13.7 38.3 43.4 10.3 11.3 23.7 58.7 136.6 16.6 15.5 15.3 5.8 29.1 15.4 69.5 23.0 18.6 48.1 50.1 37.7 16.3 21.3 6.6 26.1 56.4 4.0 14.4 22.3 10.1 8.5 13.3 13.4 18.8 29.4 12.9 9.1 12.0 9.2 33.1 11.2 9.8 14.3 11.0 18.9 18.6 67.2 15.4 23.4 15.9 68.0 68.4 33.2 49.3 16.7 14.7 64.6 15.2 38.3 18.1 17.7 21.8 17.2 27.1 24.5 18.3 11.1 24.4 19.4 32.3 25.7 18.8 11.0 37.3 19.5 23.9 23.5 17.9 18.2 17.3 23.3 21.3 27.8 23.6 21.6 32.7 24.2 28.8 44.8 31.8 31.6 87.7 120.1 59.5 32.2 40.9 89.2 35.5 26.0 34.4 21.5 32.9 18.4 93.8 6.8 84.1 28.3 5.9 20.0 48.2 22.5 24.9 36.0 31.1 26.1 51.9 19.1 4.4 37.3 22.4 47.1 80.5 21.4 27.8 25.5 21.5 67.3 54.7 10.7 30.5 40.0 127.6 31.3 25.4 66.4 74.7 57.1 63.7 23.3 70.0 51.8 119.2 18.0 22.4 21.1 79.7 66.4 15.4 13.9 23.3 48.3 6.6 54.2 30.5 59.2 15.2 64.3 155.6 4.1 119.5 21.3 14.8 66.7 CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 124.4" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 2007.5" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Group enriched" "Detected in many" 4 "amygdala: 4.8;hypothalamus: 4.1;medulla oblongata: 1.4;midbrain: 2.0;thalamus: 3.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 92.8;HDLM-2: 17.5;HSkMC: 31.4;SuSa: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB000355: , HPA051194: AB_2681381" "unprognostic (9.41e-2)" "unprognostic (7.44e-2)" "unprognostic (9.52e-5)" "unprognostic (6.81e-2)" "unprognostic (2.72e-1)" "unprognostic (4.25e-4)" "unprognostic (5.18e-5)" "unprognostic (1.54e-3)" "unprognostic (2.38e-2)" "unprognostic (2.52e-1)" "unprognostic (1.97e-1)" "unprognostic (5.37e-2)" "unprognostic (1.54e-5)" "unprognostic (2.52e-3)" "unprognostic (2.11e-1)" "unprognostic (1.40e-2)" "unprognostic (1.11e-1)" 8.3 9.0 4.8 0.4 0.6 0.2 2.1 0.1 0.5 0.6 0.0 0.2 0.7 0.3 0.0 0.1 0.3 0.5 1.2 0.3 4.1 0.1 0.1 0.7 0.0 1.4 2.0 3.2 1.3 0.2 0.0 124.4 0.7 0.6 0.1 0.6 0.9 2.7 0.6 1.8 0.2 1.3 0.2 0.6 0.2 6.5 3.7 0.2 2.4 0.3 0.0 3.5 0.5 0.7 0.1 0.0 0.0 0.0 1.7 92.8 6.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.5 0.4 0.0 0.0 0.0 0.0 17.5 0.0 0.6 0.2 8.1 0.6 0.0 0.1 31.4 0.0 0.3 4.0 0.3 0.0 0.0 0.0 0.8 0.4 0.7 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.4 0.2 16.3 0.0 0.5 0.1 0.3 0.1 0.2 0.0 3.0 1.6 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.1 0.5 0.3 4.1 1.4 2.0 0.7 0.2 3.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.1 0.0 7.9 1.5 0.0 0.0 0.0 191.3 0.0 0.0 14.0 0.0 0.3 0.0 0.0 0.9 0.0 5.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.9 12.3 0.3 0.0 0.0 2007.5 0.0 22.2 0.0 0.0 CYP1A2 "CP12, P3-450" ENSG00000140505 "Cytochrome P450 family 1 subfamily A member 2" P05177 15 74748845-74756607 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 313 "liver: 513.4" "Cell type enriched" "Detected in some" 57 "Hepatocytes: 85.7" "Group enriched" "Detected in some" 22 "liver cancer: 25.3;urothelial cancer: 6.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-BR-3: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB016531 Enhanced NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "CAB016531: AB_629359" "unprognostic (1.54e-4)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-2)" "unprognostic (5.48e-2)" "unprognostic (2.33e-2)" "unprognostic (7.41e-2)" "unprognostic (2.53e-1)" 0.2 0.3 0.5 0.2 0.5 1.0 0.1 1.6 0.8 0.0 0.2 0.0 0.2 0.2 0.4 0.1 0.2 0.2 0.1 0.5 0.5 0.2 513.4 0.4 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.3 0.3 0.6 0.2 0.0 0.1 0.3 0.2 0.3 0.6 0.1 1.4 0.0 0.1 0.1 0.0 1.3 0.4 0.3 0.8 0.5 0.1 0.0 0.6 0.2 0.0 0.0 0.1 0.3 0.4 0.8 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.1 0.4 0.9 0.6 0.1 0.0 0.7 0.3 0.1 0.1 0.0 0.0 0.3 0.1 1.3 0.7 1.3 0.0 0.2 0.9 0.3 0.4 0.3 0.2 0.9 0.8 0.3 0.1 0.7 0.7 0.3 0.6 2.3 0.1 0.6 0.5 0.2 0.2 0.3 0.4 0.3 0.3 0.3 0.2 0.5 0.3 0.9 0.3 1.5 0.3 0.5 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.5 0.2 0.2 2.1 0.4 0.2 0.4 0.1 0.1 0.5 0.5 1.6 0.8 0.5 0.5 0.6 0.5 0.6 0.1 0.6 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 85.7 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 11 "Gastric mucus-secreting cells: 3.1;Hepatocytes: 9.5;Proximal enterocytes: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.2 0.2 0.1 0.2 32.4 0.0 0.1 1.6 0.0 1.7 0.0 0.1 0.0 0.0 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.6 13.9 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.1 0.0 0.0 0.0 0.4 9.5 0.0 0.0 0.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 309 "liver: 10379.8" "Cell type enriched" "Detected in many" 58 "Hepatocytes: 6272.7" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.2" "Group enriched" "Detected in many" 16 "dendritic cells: 6.2;T-cells: 2.5" "Cell line enhanced" "Detected in many" "HaCaT: 11.0;HL-60: 8.9;HMC-1: 8.9;NB-4: 24.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" 2.8 2.9 5.4 0.6 5.4 0.8 3.0 9.1 7.5 4.9 3.0 5.0 1.4 4.5 8.3 16.7 5.5 2.5 2.1 5.5 5.5 9.1 10379.8 2.6 2.0 6.1 5.5 4.1 12.4 0.6 4.1 1.4 6.7 5.3 1.2 11.5 3.6 6.1 2.8 13.8 2.2 2.2 5.0 7.2 6.7 3.7 6.3 1.7 4.0 0.9 33.6 3.5 3.2 7.5 0.1 0.0 0.3 1.0 3.5 1.9 0.7 1.6 4.5 0.0 0.3 0.0 2.7 1.4 0.2 0.5 0.0 11.0 0.0 0.2 0.4 0.3 1.5 1.8 0.2 1.3 0.6 8.9 8.9 1.0 0.2 0.0 0.7 1.9 0.0 3.1 0.6 0.4 1.0 0.7 0.6 24.0 6.4 4.3 0.4 0.4 6.1 0.0 2.0 0.0 0.0 0.0 4.2 0.0 0.6 0.2 0.3 0.9 0.0 1.4 0.4 2.3 1.0 2.2 1.0 3.0 1.5 7.4 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.1 0.6 6.2 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.2 5.4 5.4 9.1 7.5 5.5 5.5 6.1 5.5 6.7 5.0 6.3 7.5 0.8 0.0 1.1 5.5 9.2 2.3 0.2 0.7 0.6 5.7 0.6 0.5 2.8 48.6 1.9 0.0 2.1 0.0 0.4 0.1 0.0 1.6 2.1 0.6 0.8 4.6 0.0 67.6 6.7 1.3 0.1 1.1 1.5 0.5 1.3 0.7 67.1 6272.7 0.0 8.4 5.3 0.0 0.0 108.0 2.8 2.1 1.5 0.3 0.0 1.9 0.4 0.7 0.0 2.0 2.2 3.2 0.0 2.6 0.3 0.6 0.0 0.6 2.2 5.8 0.0 0.2 0.6 4.1 4.2 2.0 7.5 0.1 5.7 0.2 0.0 0.0 CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 40 "Hepatocytes: 2612.9;Proximal enterocytes: 1685.2" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;NB-4: 2.2;RPMI-8226: 3.4;SCLC-21H: 1.3;SH-SY5Y: 2.0" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" 0.3 3.8 0.1 1.1 0.3 0.0 0.3 0.0 0.8 0.1 0.0 4.6 797.6 0.6 0.2 0.4 0.1 0.6 0.1 0.1 0.0 4.9 3796.2 0.1 0.9 0.0 0.0 0.1 43.4 0.0 1.0 0.0 0.0 0.2 2.2 0.4 0.3 0.0 2.4 1.9 853.0 0.0 0.0 0.1 1.1 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.8 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.2 0.2 0.0 0.0 0.0 0.8 3.4 0.0 0.1 1.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 2.2 0.4 0.8 0.2 0.0 0.0 0.0 0.0 0.4 32.9 0.0 0.0 0.0 0.3 0.0 5.6 0.0 0.1 0.4 0.0 0.0 1.4 0.0 26.7 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 30.0 2612.9 0.0 0.0 0.6 29.6 2.0 52.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 38.9 0.0 0.0 0.6 1685.2 3.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.9 0.1 2.3 0.5 16.1 1.1 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 DAD1 OST2 ENSG00000129562 "Defender against cell death 1" P61803 14 22564907-22589224 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028882 Uncertain Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Endoplasmic reticulum" "HPA028882: AB_10602214" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (2.02e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (9.43e-3)" "unprognostic (3.06e-2)" "unprognostic (6.09e-2)" "unprognostic (1.99e-2)" "unprognostic (9.64e-2)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (3.08e-1)" "unprognostic (1.93e-1)" "unprognostic (1.37e-3)" 204.0 229.3 209.2 159.1 224.4 129.0 224.0 236.2 259.4 229.6 252.2 197.7 165.8 184.3 473.8 187.0 230.5 190.8 202.6 211.4 238.0 296.8 275.7 183.4 169.6 240.2 218.7 174.5 200.2 254.1 201.6 141.8 238.7 145.5 209.9 86.2 286.3 205.5 156.6 137.2 173.8 206.6 237.2 165.3 197.0 150.7 219.2 211.6 272.8 197.5 191.0 200.0 163.4 252.0 373.3 344.7 274.6 375.8 740.2 529.9 238.3 387.0 473.0 340.5 478.1 219.6 520.1 233.7 242.1 453.1 381.4 330.0 291.1 375.7 543.3 319.8 265.1 228.5 180.9 886.0 514.5 321.2 315.8 395.8 498.7 356.0 454.4 383.1 506.2 220.9 176.4 532.1 509.9 459.3 153.6 391.4 169.7 816.1 557.8 211.7 232.4 306.7 503.2 306.1 211.5 263.4 294.9 416.1 445.9 328.7 251.4 323.1 381.1 291.8 232.2 358.2 248.3 391.2 502.6 308.5 263.8 225.5 431.0 532.4 421.9 460.9 528.4 371.9 518.9 527.2 543.8 501.4 401.0 477.1 564.8 497.6 481.5 437.2 332.3 783.9 560.3 941.8 209.2 224.4 236.2 259.4 211.4 238.0 240.2 218.7 238.7 237.2 219.2 252.0 357.9 160.3 161.7 15.0 183.9 198.3 188.3 581.8 149.7 25.1 201.0 274.6 173.8 187.3 315.2 255.6 27.1 260.9 204.6 174.8 215.2 525.4 196.8 270.3 242.9 267.8 135.7 130.2 10.6 415.2 383.1 276.5 145.2 255.6 302.6 150.8 187.7 231.9 350.3 21.9 11.0 242.3 360.1 146.2 224.8 101.5 214.3 166.8 330.8 8.4 217.3 216.8 198.8 18.1 42.5 396.8 160.7 199.0 408.6 172.5 244.8 420.8 393.7 42.6 151.2 141.5 291.0 300.3 128.1 179.6 215.8 289.0 211.7 266.6 183.8 174.4 DAPK1 "DAPK, ROCO3" ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708634 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 139.1;Excitatory neurons: 120.2;Inhibitory neurons: 155.9;Kupffer cells: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.7;eosinophil: 8.7;intermediate monocyte: 14.0;myeloid DC: 4.8;non-classical monocyte: 15.2;plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 56 "dendritic cells: 6.2;granulocytes: 8.7;monocytes: 15.2" "Cell line enhanced" "Detected in many" "HMC-1: 97.6;HUVEC TERT2: 56.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037302, HPA040472, HPA048436" Approved Approved Centrosome NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Centrosome "CAB037302: AB_1078622, HPA040472: AB_2677001, HPA048436: AB_2680390" "unprognostic (2.55e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.75e-1)" "unprognostic (1.88e-2)" "unprognostic (5.77e-3)" "unprognostic (2.19e-2)" "unprognostic (2.77e-3)" "unprognostic (8.31e-3)" "unprognostic (8.76e-2)" "unprognostic (2.40e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-3)" 22.9 5.9 12.1 11.8 16.4 5.4 5.9 2.2 20.5 9.6 12.6 27.1 10.1 7.9 18.8 5.5 15.2 28.0 5.2 22.8 7.6 22.0 27.6 37.5 12.5 7.6 7.6 46.0 29.2 6.7 23.4 27.3 13.8 5.2 9.2 11.5 13.7 8.5 1.8 5.0 14.4 9.4 7.8 22.8 19.5 8.1 8.6 41.8 9.8 2.3 6.8 14.5 3.8 7.5 0.0 47.5 22.5 15.8 0.7 0.3 35.4 3.1 4.4 18.3 20.4 6.8 0.3 0.4 4.7 1.0 0.2 43.9 13.9 1.0 7.9 0.4 11.4 23.4 6.6 23.7 19.5 0.0 97.6 1.4 7.5 3.5 1.4 28.5 56.3 6.5 17.8 9.6 15.4 1.5 7.0 0.0 25.4 44.4 0.0 2.0 19.8 0.1 50.6 47.6 10.2 11.3 0.0 4.6 20.1 32.7 0.0 15.2 0.4 0.1 0.3 0.1 0.1 36.9 8.1 0.0 0.2 6.4 3.0 1.7 6.7 8.7 0.0 14.0 0.0 0.1 0.0 0.0 4.8 0.0 0.0 0.1 2.0 0.1 15.2 6.2 0.0 3.0 12.1 16.4 2.2 20.5 22.8 7.6 7.6 7.6 13.8 7.8 8.6 7.5 8.8 51.3 72.2 139.1 2.7 3.6 0.8 1.2 0.6 19.4 1.3 2.3 2.4 31.5 24.3 22.0 2.1 6.8 9.5 1.1 1.9 33.8 1.8 30.2 7.9 17.3 0.0 12.8 120.2 23.0 19.0 12.3 26.5 58.6 24.1 22.1 68.9 20.8 22.7 18.5 155.9 9.3 0.0 85.7 18.3 3.1 14.9 57.1 12.4 18.7 41.2 14.6 2.1 6.6 4.7 35.8 1.9 13.5 6.2 3.2 9.6 7.0 10.2 2.9 0.0 1.5 3.9 3.4 7.2 1.6 3.1 14.2 2.8 3.4 3.7 14.9 DAXX DAP6 ENSG00000204209 "Death domain associated protein" Q9UER7 6 33318558-33323016 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002224, HPA008736, HPA008797, CAB025546, HPA065779" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nuclear bodies" "CAB002224: AB_563688, CAB025546: , HPA008736: AB_1078625, HPA008797: AB_2797218, HPA065779: AB_2685558" "prognostic favorable (6.05e-4)" "unprognostic (2.90e-1)" "unprognostic (9.66e-2)" "unprognostic (4.04e-2)" "unprognostic (8.55e-2)" "unprognostic (1.36e-1)" "unprognostic (1.46e-3)" "unprognostic (3.48e-1)" "unprognostic (1.92e-1)" "unprognostic (8.58e-3)" "unprognostic (1.34e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (6.32e-7)" "unprognostic (2.43e-1)" "unprognostic (5.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" 27.5 33.6 6.4 4.0 6.2 8.1 25.3 5.0 12.0 28.4 2.9 27.9 8.1 27.8 18.9 30.8 28.6 7.2 22.3 6.8 5.8 23.2 25.0 24.0 8.7 6.9 5.9 23.8 23.1 19.3 22.1 7.9 5.5 25.1 10.8 5.2 24.2 9.3 35.4 28.8 30.4 10.6 4.8 44.3 25.0 36.7 6.7 23.5 24.2 12.5 27.3 27.2 25.9 9.0 20.8 0.1 38.0 15.6 16.0 16.0 30.1 27.4 76.7 61.5 43.6 1.6 11.8 58.5 14.8 33.3 65.5 11.8 0.3 46.1 62.5 29.9 39.6 52.0 29.9 39.9 26.5 37.0 17.0 27.0 32.5 25.8 31.0 22.7 15.5 16.2 39.1 21.2 32.1 23.2 29.7 54.1 1.2 0.2 9.1 35.2 5.6 41.8 11.7 1.6 49.7 20.2 0.0 0.9 22.7 14.8 17.5 0.5 22.9 26.3 29.1 0.5 0.3 35.4 58.3 66.4 23.3 23.0 27.7 24.1 22.5 47.3 55.6 28.9 54.9 58.8 48.3 61.3 28.2 56.8 44.5 49.6 22.9 62.9 35.1 27.0 59.0 70.5 6.4 6.2 5.0 12.0 6.8 5.8 6.9 5.9 5.5 4.8 6.7 9.0 18.4 6.4 22.8 5.2 45.3 58.5 23.5 36.2 48.3 19.2 25.8 19.4 7.9 18.6 27.6 12.9 18.8 25.2 41.3 23.3 23.5 38.5 15.7 14.5 54.8 23.9 21.0 27.1 3.7 38.3 35.9 25.2 16.8 23.6 37.9 12.9 16.4 14.5 24.3 15.2 3.8 21.2 12.2 17.2 42.5 7.6 17.7 19.7 24.9 6.5 48.8 29.9 52.5 5.0 4.6 45.4 21.8 23.3 38.7 31.8 20.3 14.4 15.6 111.1 13.1 18.7 19.9 63.8 41.5 45.9 60.9 24.8 42.8 24.1 22.0 35.7 DBI "ACBD1, ACBP" ENSG00000155368 "Diazepam binding inhibitor, acyl-CoA binding protein" P07108 2 119366921-119372560 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 2215.1;Proximal tubular cells: 2834.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 2479.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051428 Approved NA NA 9100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA051428: AB_2681482" "unprognostic (1.24e-1)" "prognostic favorable (5.77e-5)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (1.92e-2)" "unprognostic (7.28e-3)" "unprognostic (1.70e-3)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.45e-1)" 358.3 153.9 486.0 158.7 470.8 121.9 717.3 495.6 726.7 218.6 452.3 322.8 312.8 73.5 653.7 667.7 85.8 129.7 515.4 493.0 498.5 536.2 971.1 236.0 182.9 499.4 495.1 86.0 143.8 866.9 76.9 116.3 510.0 451.5 297.3 116.3 369.9 215.1 273.0 451.0 229.6 97.2 512.7 115.5 185.1 201.3 487.6 173.3 133.7 460.5 324.5 136.5 327.7 516.4 543.0 276.9 557.1 257.2 1339.7 1131.9 350.7 281.3 708.7 387.0 746.1 580.6 427.8 747.3 312.1 440.6 938.5 277.9 397.0 588.3 345.9 498.2 262.1 641.4 279.9 775.8 335.6 206.1 2479.2 648.2 376.5 596.2 222.1 255.4 464.3 358.8 77.0 679.2 558.8 559.1 436.5 585.9 370.2 349.7 429.7 157.4 541.4 658.5 948.1 816.5 263.2 210.1 235.3 548.5 634.9 388.8 338.0 952.8 332.5 259.3 329.8 288.8 346.3 220.9 170.5 610.0 365.7 364.8 315.3 1180.7 439.9 1077.9 472.9 489.1 347.3 461.4 367.8 465.2 748.8 505.3 279.1 419.2 285.8 450.7 402.5 791.0 615.7 792.2 486.0 470.8 495.6 726.7 493.0 498.5 499.4 495.1 510.0 512.7 487.6 516.4 505.2 150.6 613.0 46.0 256.7 289.2 249.4 724.2 190.1 37.9 806.5 1025.9 1079.6 663.4 390.0 310.8 14.6 796.5 395.6 737.5 1197.4 466.9 844.4 154.8 194.7 206.2 371.3 108.8 5.2 670.3 643.2 258.2 243.1 185.6 433.4 219.4 167.8 2215.1 1069.4 30.3 3.9 495.0 524.9 305.0 785.7 325.7 152.2 476.1 1058.3 15.0 871.5 928.6 552.0 33.2 25.0 372.7 612.0 127.5 192.0 355.0 753.6 2834.8 340.5 59.1 151.2 267.2 289.9 462.0 30.1 972.6 684.9 516.3 260.8 456.0 673.2 361.0 DCC "IGDCC1, NTN1R1" ENSG00000187323 "DCC netrin 1 receptor" P43146 18 52340197-53535903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.9;testis: 7.6" "Cell type enhanced" "Detected in some" "Early spermatids: 205.7;Excitatory neurons: 439.7;Inhibitory neurons: 455.8;Late spermatids: 174.9;Oligodendrocyte precursor cells: 1305.9" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 36.4;U-266/70: 112.5;U-266/84: 57.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055376, HPA069552" Enhanced Approved "Golgi apparatus" NA NA 64000 "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" "HPA055376: AB_2682798, HPA069552: AB_2686151" "unprognostic (1.96e-3)" "unprognostic (1.69e-2)" "unprognostic (3.13e-1)" "unprognostic (3.90e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-3)" "unprognostic (2.59e-1)" "unprognostic (5.59e-2)" "unprognostic (2.00e-1)" "unprognostic (2.58e-1)" "unprognostic (8.22e-4)" "unprognostic (4.14e-2)" "unprognostic (1.27e-4)" "unprognostic (7.21e-2)" "unprognostic (1.84e-2)" "unprognostic (1.42e-1)" "unprognostic (2.69e-3)" 0.0 0.6 1.2 0.2 6.3 0.0 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.0 6.9 3.6 0.2 0.0 1.4 0.0 0.7 4.7 0.1 0.3 0.0 0.6 0.0 1.5 0.3 0.1 0.3 0.1 1.2 0.0 0.1 0.1 0.0 0.0 0.2 0.2 7.6 1.1 1.0 0.0 0.0 0.3 0.1 0.1 0.9 0.1 0.1 36.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.1 112.5 57.1 0.0 6.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 6.3 0.0 3.9 6.9 3.6 0.7 4.7 1.5 0.0 1.1 0.9 1.4 0.0 6.0 10.1 0.3 0.0 0.1 0.0 0.0 2.5 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 205.7 0.0 0.0 0.1 0.0 0.0 439.7 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 455.8 0.0 0.0 0.0 0.0 174.9 1.2 0.2 0.0 54.4 0.0 0.2 0.0 1305.9 58.6 0.0 0.0 1.2 5.7 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.1 2.6 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB009108: AB_2090601, HPA034635: AB_2674256, HPA071875: " "unprognostic (1.14e-1)" "unprognostic (7.19e-2)" "unprognostic (1.33e-3)" "unprognostic (4.08e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-1)" "unprognostic (4.61e-3)" "unprognostic (2.11e-2)" "unprognostic (2.79e-1)" "unprognostic (3.73e-3)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.34e-7)" "unprognostic (5.41e-2)" "unprognostic (3.11e-1)" "unprognostic (7.86e-3)" "unprognostic (1.12e-3)" 43.3 40.0 90.5 27.0 94.7 23.7 37.4 76.4 113.2 44.3 20.8 51.3 22.2 51.4 17.0 42.6 38.7 28.2 82.6 99.9 80.1 27.6 18.2 36.0 22.8 110.9 85.1 39.2 28.6 118.0 61.2 32.6 112.6 30.0 25.5 43.5 56.3 38.0 87.6 44.2 32.2 49.9 76.0 26.5 39.5 51.3 101.9 34.7 31.3 63.4 24.6 47.6 39.0 116.2 65.0 74.7 68.4 71.9 122.5 90.7 55.2 102.0 105.2 127.0 89.9 99.9 48.6 88.8 40.8 213.0 70.1 63.5 84.3 129.5 96.1 111.2 85.0 92.5 55.6 84.7 94.4 50.7 109.3 109.6 62.0 138.3 82.3 86.9 110.3 79.4 40.3 61.4 97.3 55.6 92.8 52.5 74.0 78.6 78.3 82.3 120.1 63.8 70.2 39.6 83.3 74.1 57.1 67.7 60.6 59.0 43.5 36.5 84.3 115.0 82.7 50.0 77.2 37.8 32.7 78.9 107.6 81.4 82.5 8.3 11.3 12.7 14.4 13.0 11.7 10.1 8.2 10.8 11.2 6.8 5.6 6.3 9.2 9.2 15.6 8.8 7.7 16.5 90.5 94.7 76.4 113.2 99.9 80.1 110.9 85.1 112.6 76.0 101.9 116.2 28.6 32.1 25.4 9.8 23.2 10.1 10.3 19.1 25.6 27.2 19.6 17.8 56.4 18.6 20.0 29.5 25.0 29.8 19.4 41.0 19.6 22.5 7.3 21.5 32.8 26.6 16.7 27.3 28.4 19.9 27.1 25.1 49.5 27.8 29.2 30.8 29.6 19.9 28.8 90.9 26.7 31.8 24.4 21.0 11.3 9.3 44.7 21.2 16.0 8.4 27.3 14.9 23.7 12.1 29.7 26.6 33.6 51.9 24.7 9.6 34.2 19.6 19.4 45.5 19.7 28.3 30.0 40.6 38.5 29.0 11.8 25.2 20.0 33.9 24.9 10.7 DDB2 "DDBB, FLJ34321, UV-DDB2, XPE" ENSG00000134574 "Damage specific DNA binding protein 2" Q92466 11 47214465-47239217 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;monocytes: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025912, HPA058406" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cell Junctions" "CAB025912: , HPA058406: AB_2683708" "prognostic favorable (7.29e-4)" "prognostic favorable (1.58e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.20e-4)" "unprognostic (4.29e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-2)" "unprognostic (6.18e-2)" "unprognostic (2.25e-1)" "unprognostic (3.58e-3)" "unprognostic (3.53e-1)" "unprognostic (1.94e-1)" "unprognostic (4.57e-3)" "unprognostic (1.21e-2)" "unprognostic (4.25e-2)" "unprognostic (9.82e-3)" "unprognostic (1.07e-1)" 13.2 22.5 2.6 8.2 3.2 11.6 13.5 3.4 3.6 12.5 3.4 12.8 7.6 12.7 11.7 24.8 17.6 12.5 6.8 2.5 2.4 4.4 27.0 12.2 14.7 3.4 2.7 11.6 14.4 4.8 4.7 6.8 3.5 9.7 14.9 2.3 14.4 11.7 6.2 46.7 10.2 13.9 2.7 11.3 9.5 4.5 3.2 23.5 5.5 6.9 17.0 11.2 14.1 3.6 23.7 62.3 25.9 19.3 16.6 32.7 29.9 26.0 58.8 32.0 37.1 10.1 14.1 56.6 5.3 23.2 23.6 40.8 14.6 51.8 15.7 14.5 27.5 13.3 55.7 46.7 15.8 15.9 34.4 43.4 58.0 15.9 35.2 10.2 94.2 14.7 3.5 27.0 52.7 44.4 60.4 7.7 8.4 31.1 22.3 30.3 5.6 30.6 13.5 22.7 13.2 16.7 31.2 8.7 8.1 30.8 56.1 5.5 41.2 96.8 44.1 21.3 12.6 27.6 22.4 12.5 37.0 20.2 35.9 9.8 12.8 20.2 19.3 18.4 18.8 18.3 20.1 18.8 10.4 14.5 14.8 15.7 3.7 14.1 15.8 0.3 47.7 15.9 2.6 3.2 3.4 3.6 2.5 2.4 3.4 2.7 3.5 2.7 3.2 3.6 13.8 16.0 22.2 7.8 25.1 38.9 39.7 28.1 75.1 5.0 18.0 25.8 7.8 11.5 16.3 5.5 10.4 3.6 21.3 11.1 9.8 12.5 1.5 5.2 8.1 19.5 7.7 19.1 6.6 13.8 9.0 16.0 18.3 9.5 22.8 31.2 15.0 16.6 17.5 1.7 1.4 12.6 16.2 17.5 12.8 2.1 19.0 16.8 19.6 24.4 135.5 9.6 35.0 1.0 10.6 19.9 9.8 10.5 34.1 8.9 15.7 7.7 13.9 12.8 0.0 12.1 14.0 3.1 8.6 34.5 30.3 1.5 34.3 25.4 16.5 26.5 DDIT3 "CHOP, CHOP10, GADD153" ENSG00000175197 "DNA damage inducible transcript 3" P35638 12 57516588-57521737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Growth arrest, Stress response, Transcription, Transcription regulation, Unfolded protein response, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 170.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 784.2;hTERT-HME1: 399.9;SK-MEL-30: 409.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058416, HPA068416" Uncertain Supported Nucleoplasm No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA058416: AB_2683712, HPA068416: AB_2685985" "unprognostic (1.12e-1)" "unprognostic (5.33e-2)" "unprognostic (2.20e-3)" "unprognostic (4.92e-2)" "unprognostic (7.86e-3)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-4)" "unprognostic (8.55e-2)" "unprognostic (1.26e-3)" "unprognostic (9.40e-3)" "unprognostic (4.92e-2)" "unprognostic (4.16e-2)" "unprognostic (3.52e-2)" "unprognostic (3.70e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-1)" "unprognostic (6.76e-2)" 65.3 66.2 90.6 16.1 97.8 196.5 64.3 97.4 145.5 51.0 92.9 52.0 20.7 39.1 109.3 31.6 41.2 32.1 85.1 89.0 99.2 106.4 81.7 55.4 18.8 95.9 98.4 57.4 37.3 80.5 81.4 37.6 97.1 45.5 26.6 123.1 43.3 25.8 44.8 48.7 28.0 29.2 95.5 34.2 44.4 40.9 106.4 17.8 182.1 55.4 17.5 56.2 49.5 129.5 17.8 16.1 10.1 34.5 90.7 61.0 53.8 48.2 106.0 70.1 65.4 57.2 45.7 25.3 46.9 14.3 186.7 21.4 38.5 7.3 72.2 21.0 15.5 19.9 19.9 42.3 784.2 31.8 29.3 175.7 152.7 118.6 399.9 81.7 16.9 26.5 86.4 94.0 31.2 10.8 21.1 41.5 19.7 37.3 37.5 11.8 220.7 22.3 25.0 22.3 20.9 15.3 14.2 16.2 409.0 37.2 34.4 82.8 9.9 47.5 20.2 45.4 42.0 164.4 60.3 26.8 57.4 29.1 85.8 121.1 17.9 48.8 25.1 16.6 22.7 48.3 17.9 23.6 12.8 44.8 34.1 31.1 170.7 35.6 19.4 15.9 23.8 18.0 90.6 97.8 97.4 145.5 89.0 99.2 95.9 98.4 97.1 95.5 106.4 129.5 237.9 19.2 55.1 17.0 96.6 56.3 176.5 93.1 177.0 114.9 86.3 265.7 177.9 37.1 56.7 22.0 91.8 42.3 101.8 265.7 115.4 43.3 9.5 111.3 39.4 62.3 230.7 12.8 9.6 16.0 17.5 115.7 74.5 82.4 204.0 26.3 27.5 20.1 45.7 55.5 14.5 218.4 101.7 30.4 81.6 6.3 28.0 81.5 88.9 6.5 8.2 156.1 17.5 14.1 23.0 33.0 300.0 38.0 43.2 115.1 61.7 61.6 38.1 160.0 13.1 56.9 122.2 77.7 15.6 91.5 45.7 107.8 89.7 37.2 127.2 65.1 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DDX10 "Dbp4, HRH-J8" ENSG00000178105 "DEAD-box helicase 10" Q13206 11 108665069-108940927 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 133.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 162.3" "Low region specificity" "Detected in all" HPA004691 Approved Approved Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoli "HPA004691: AB_1078629" "unprognostic (9.49e-2)" "unprognostic (9.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (7.97e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (2.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.00e-1)" "prognostic favorable (2.14e-5)" "unprognostic (5.20e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-1)" "unprognostic (2.43e-3)" 7.3 6.8 3.7 6.8 3.9 6.3 9.2 4.2 5.1 7.9 1.6 6.6 5.0 10.4 7.3 7.3 8.5 5.0 6.1 4.4 3.0 11.7 7.0 5.3 8.5 2.2 3.3 10.6 7.5 7.6 4.5 7.8 2.8 7.0 7.7 11.1 6.2 6.8 7.1 7.6 4.7 9.9 2.0 7.2 5.8 15.8 3.7 8.4 7.8 4.7 8.8 10.3 6.9 4.0 21.3 20.7 19.3 27.0 18.5 15.0 20.0 22.6 12.2 26.7 26.3 59.3 30.6 71.8 41.3 17.3 28.7 23.5 55.4 27.3 37.8 27.8 25.0 48.5 11.6 22.3 33.0 49.9 22.4 13.5 21.0 30.4 37.6 15.9 24.6 18.4 70.0 7.8 26.7 14.0 42.7 42.5 24.8 40.0 31.0 35.9 31.3 67.9 16.3 18.2 35.2 18.4 31.7 27.4 12.3 25.4 33.4 17.7 26.0 27.8 28.3 26.8 30.9 11.7 22.0 162.3 9.5 59.7 28.7 1.6 4.4 1.2 7.8 6.7 10.8 10.5 7.0 9.6 8.5 12.0 7.4 7.2 0.4 10.1 6.8 8.0 6.3 4.4 3.7 3.9 4.2 5.1 4.4 3.0 2.2 3.3 2.8 2.0 3.7 4.0 20.2 16.0 28.8 29.0 23.7 28.4 24.5 11.0 28.5 21.1 14.9 11.9 20.5 12.8 17.6 3.7 95.9 24.3 19.8 9.7 19.6 18.7 47.2 16.9 31.4 24.3 15.0 11.6 84.7 21.3 21.3 26.3 15.3 23.3 14.5 28.1 10.4 11.0 14.7 18.5 75.9 9.7 6.1 8.8 12.0 10.9 29.5 15.4 7.2 51.5 20.6 8.9 27.8 67.3 59.5 17.2 5.7 21.4 13.2 24.8 3.7 133.3 13.1 25.1 13.1 32.6 20.3 63.0 45.8 19.3 29.0 25.9 17.7 26.6 15.6 14.8 DDX3X "DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3 X-linked" O00571 X 41333348-41364472 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 887.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved Nucleoplasm,Cytosol NA NA 260000 "Cluster 18: Basophils - Vesicular transport" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol Nucleoplasm "HPA001648: AB_1078635, HPA005631: AB_1078633, HPA059585: AB_2684073" "unprognostic (2.42e-2)" "unprognostic (1.11e-1)" "unprognostic (8.01e-3)" "unprognostic (1.66e-1)" "unprognostic (8.12e-2)" "unprognostic (6.43e-2)" "unprognostic (1.17e-3)" "unprognostic (1.88e-1)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.25e-2)" "unprognostic (2.05e-1)" "unprognostic (1.51e-1)" "unprognostic (2.95e-1)" "unprognostic (4.77e-1)" "unprognostic (9.44e-2)" "unprognostic (2.93e-2)" 164.7 123.2 28.7 113.3 29.9 146.1 99.8 31.9 37.3 102.4 38.8 85.6 80.7 123.4 39.1 107.6 108.8 111.0 96.4 27.0 36.0 110.5 130.6 103.5 118.7 33.6 29.8 108.1 76.9 133.0 52.5 107.3 34.2 68.7 75.8 81.9 72.9 64.8 126.9 91.2 81.6 145.1 32.4 103.2 84.4 43.0 30.9 169.6 104.3 112.5 111.5 153.3 97.7 34.7 230.5 225.6 236.3 122.3 273.6 211.1 136.4 150.6 239.3 167.1 132.3 238.8 141.4 2.5 103.9 185.8 212.4 149.4 292.2 235.0 248.3 130.2 232.9 132.6 237.6 152.1 140.5 253.8 236.4 159.1 150.9 278.4 270.3 204.1 258.3 131.5 258.4 134.5 158.9 157.8 163.0 83.2 212.2 121.3 114.2 187.8 223.3 182.6 143.7 279.1 147.1 220.0 352.3 184.3 194.3 248.9 158.9 172.4 224.5 159.6 166.3 178.7 188.2 153.6 194.0 215.7 161.5 156.1 151.5 50.8 39.0 30.7 23.3 35.3 33.5 21.0 23.3 26.3 34.7 13.0 25.4 25.3 54.0 30.7 39.4 11.7 24.8 37.8 28.7 29.9 31.9 37.3 27.0 36.0 33.6 29.8 34.2 32.4 30.9 34.7 466.5 86.6 150.0 66.9 280.1 264.3 160.5 63.7 191.8 77.1 295.1 237.6 158.0 81.5 96.5 58.8 131.3 94.6 415.2 231.1 43.0 64.3 370.6 261.1 237.7 238.5 183.7 113.0 43.8 85.6 95.1 191.8 178.9 290.1 165.5 180.6 144.2 174.5 123.1 60.6 47.1 161.4 71.2 208.7 269.1 887.5 66.5 319.0 128.1 47.8 112.2 90.0 79.3 44.7 63.1 114.1 156.7 62.8 241.8 145.0 234.9 87.3 102.5 127.1 72.3 351.4 210.1 30.6 57.7 212.6 333.4 172.9 342.4 144.8 129.1 225.8 DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64498254-64508199 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005868, HPA020043, HPA071154" Supported Supported Nucleoplasm,Nucleoli No No 310000 "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "CAB005868: AB_446484, HPA020043: AB_1847572, HPA071154: " "unprognostic (6.64e-2)" "unprognostic (6.98e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.94e-2)" "unprognostic (5.08e-2)" "unprognostic (9.85e-2)" "unprognostic (5.80e-2)" "unprognostic (1.61e-2)" "unprognostic (3.17e-2)" "unprognostic (4.71e-2)" "unprognostic (3.03e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.17e-1)" "unprognostic (9.28e-3)" 202.9 124.0 75.2 75.7 80.0 219.5 163.4 93.4 91.3 190.4 122.8 176.8 36.1 181.7 61.9 136.9 181.2 186.4 109.8 83.6 83.8 113.6 157.5 185.9 124.7 85.5 79.7 134.2 83.3 177.7 118.9 119.4 79.0 122.8 157.7 211.7 112.0 144.8 165.7 130.6 116.3 274.6 65.4 127.5 137.1 88.7 83.2 272.5 172.8 107.5 157.5 228.2 128.9 100.2 204.7 85.5 353.1 144.4 316.2 316.7 134.1 221.4 349.8 306.9 300.3 98.2 105.3 299.7 102.0 364.8 238.1 87.1 361.6 291.5 428.2 107.7 76.0 211.2 84.5 81.6 216.6 383.9 186.3 301.4 306.8 270.2 264.1 241.5 362.2 303.6 174.3 247.3 284.0 108.7 520.4 44.8 159.5 294.5 32.0 310.1 286.7 239.1 201.8 145.6 151.0 305.7 181.5 167.6 284.0 326.5 138.5 132.1 158.2 123.0 146.3 170.0 207.3 112.2 283.9 622.0 166.6 140.5 184.2 232.6 160.6 170.0 117.2 143.3 149.8 111.5 105.4 125.4 148.5 106.3 107.6 109.4 86.6 112.2 197.1 85.5 135.9 319.9 75.2 80.0 93.4 91.3 83.6 83.8 85.5 79.7 79.0 65.4 83.2 100.2 990.8 535.2 690.9 200.8 909.4 879.5 1536.4 837.0 618.1 403.5 433.3 393.7 249.6 346.0 855.7 369.6 335.7 439.9 1284.6 521.5 334.6 476.2 603.0 1021.9 987.2 767.7 664.1 309.7 187.9 419.2 371.3 733.5 452.1 1288.8 874.3 647.9 528.7 254.3 445.8 420.6 165.7 475.9 801.5 577.8 629.4 136.9 415.4 833.2 432.2 280.1 800.2 587.1 777.5 291.6 325.7 464.2 598.6 437.8 661.5 537.7 552.6 287.5 737.9 550.4 493.0 1437.7 961.5 407.6 399.1 466.4 746.0 887.3 1043.4 745.0 424.7 1056.4 DDX6 "HLR2, RCK, Rck/p54" ENSG00000110367 "DEAD-box helicase 6" P26196 11 118747763-118791164 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004668, HPA024201, HPA026644" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA 19000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" "Cytoplasmic bodies" Cytosol "CAB004668: AB_436960, HPA024201: AB_10603562, HPA026644: AB_1847582" "unprognostic (1.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.89e-1)" "unprognostic (3.40e-2)" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "prognostic unfavorable (6.56e-4)" "unprognostic (3.43e-1)" "unprognostic (1.48e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (7.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.91e-3)" "unprognostic (1.88e-1)" "unprognostic (9.58e-2)" "unprognostic (4.55e-2)" 31.5 28.4 29.1 34.9 36.0 69.0 34.9 50.7 31.9 33.2 12.7 30.0 23.7 30.5 30.5 33.1 29.1 23.6 37.2 31.5 35.4 30.6 34.2 27.3 49.0 28.4 29.3 48.8 30.7 28.3 17.3 31.6 25.2 32.9 27.9 48.7 32.4 29.2 43.2 27.2 26.2 30.6 29.9 45.4 29.9 28.8 37.1 54.9 37.5 41.9 60.9 30.0 21.9 36.6 33.9 50.4 73.6 71.7 64.0 64.8 47.2 45.6 62.0 43.0 40.4 72.1 50.9 77.6 47.1 78.8 44.3 53.2 88.8 69.1 69.0 62.7 17.4 154.5 30.8 57.1 42.0 110.9 55.8 67.1 49.5 63.5 100.8 54.8 69.1 53.2 72.5 110.4 59.2 96.8 81.0 52.1 53.3 50.1 33.6 89.3 59.2 60.1 50.1 92.7 48.7 63.9 84.7 67.2 28.5 56.2 79.2 44.2 81.2 67.2 38.4 39.8 47.6 34.1 47.8 91.7 26.8 52.2 59.2 13.8 4.8 13.2 10.2 6.2 12.3 12.1 10.0 10.8 5.1 12.0 12.2 11.0 19.0 8.3 12.4 7.1 9.9 6.8 29.1 36.0 50.7 31.9 31.5 35.4 28.4 29.3 25.2 29.9 37.1 36.6 84.6 60.9 57.9 37.9 140.1 30.2 75.2 31.3 69.4 82.2 49.8 43.2 116.9 42.9 41.4 44.1 50.1 38.4 184.0 58.6 31.3 32.2 4.2 77.3 81.5 64.6 85.7 88.2 57.3 35.5 36.5 55.6 42.3 91.7 52.5 54.2 61.8 41.5 38.3 62.2 60.9 59.8 42.7 66.9 44.3 10.5 54.0 70.1 33.8 68.4 75.9 90.0 119.4 50.3 80.9 51.2 57.0 45.1 106.0 49.8 57.2 41.3 35.9 91.3 39.5 92.6 69.7 71.1 76.8 73.4 30.5 76.5 130.2 48.8 53.1 78.2 DEFA1 "DEF1, DEFA2, HNP-1, MRS" ENSG00000206047 "Defensin alpha 1" P59665 8 6977649-6980080 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 18020.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "NB-4: 2.1" "CAB032548, HPA052517" Enhanced "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "CAB032548: AB_2277258, HPA052517: AB_2681860" 31.6 4.3 0.7 0.6 0.8 18020.9 16.8 0.5 3.0 4.0 0.6 4.1 0.0 11.3 0.0 3.2 2.2 1.3 62.5 0.5 0.6 15.0 91.6 560.5 3.5 0.7 0.7 4.1 5.5 0.1 20.6 11.4 0.7 2.7 0.0 0.3 14.5 0.0 16.8 40.3 2.3 0.0 0.8 1803.8 6.4 3.1 0.8 37.0 15.8 0.0 0.8 3.4 5.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.5 3.0 0.5 0.6 0.7 0.7 0.7 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 DEFA1B ENSG00000240247 "Defensin alpha 1B" P59665 8 6996766-6999195 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 872.0" "Cell type enriched" "Detected in single" 37 "T-cells: 3.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052517 Supported "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA052517: AB_2681860" 2.3 0.3 0.1 0.8 0.1 872.0 1.1 0.1 2.0 0.0 0.1 0.2 0.0 0.9 0.0 0.1 0.1 0.0 3.8 0.2 0.1 0.9 9.1 52.1 0.0 0.2 0.1 0.3 0.1 0.0 1.4 7.2 0.4 0.1 0.0 0.1 9.4 0.0 0.8 0.2 0.2 0.0 0.1 150.4 0.6 0.1 0.4 27.8 1.2 5.8 1.4 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.0 0.2 0.1 0.2 0.1 0.4 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 DEFA3 "DEF3, HNP-3" ENSG00000239839 "Defensin alpha 3" P59666 8 7015869-7018297 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "bone marrow: 37615.2" "Cell type enhanced" "Detected in some" "B-cells: 17.9;Erythroid cells: 10.1;Hepatocytes: 17.0;Macrophages: 5.7;Plasma cells: 4.0;T-cells: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 19 "neutrophil: 854.3" "Lineage enriched" "Detected in many" 19 "granulocytes: 854.3" "Cell line enriched" "Detected in single" 8 "NB-4: 1.5" HPA052517 Supported "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA052517: AB_2681860" "unprognostic (8.21e-2)" 8.8 1.2 0.5 1.0 0.3 37615.2 5.0 0.2 1.2 2.0 0.3 1.3 0.0 5.6 0.0 1.0 0.7 0.2 16.1 0.2 0.3 4.4 26.1 180.2 5.3 0.4 0.6 1.3 1.6 0.0 7.6 18.8 0.5 0.8 0.0 0.2 24.2 0.0 5.0 42.1 0.7 0.0 0.5 589.4 1.8 0.6 0.6 147.9 4.5 1.1 1.3 1.1 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 24.4 3.6 44.3 1.2 1.6 2.3 1.0 0.8 1.0 1.1 6.9 0.3 854.3 0.4 2.6 1.4 0.3 6033.6 0.5 0.3 0.2 1.2 0.2 0.3 0.4 0.6 0.5 0.5 0.6 0.2 0.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.8 17.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 DEK D6S231E ENSG00000124795 "DEK proto-oncogene" P35659 6 18223860-18264548 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015226, HPA054505, HPA057799" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "CAB015226: , HPA054505: AB_2682508, HPA057799: AB_2683530" "unprognostic (6.35e-2)" "unprognostic (6.11e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (3.66e-1)" "unprognostic (5.02e-3)" "prognostic unfavorable (9.65e-4)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.61e-3)" "unprognostic (6.49e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (2.31e-1)" "unprognostic (3.78e-1)" 50.8 43.0 17.3 82.4 20.1 158.6 63.1 29.6 25.4 48.1 19.8 74.8 76.9 74.2 29.9 65.4 45.6 49.0 61.0 17.3 18.3 46.0 68.0 53.2 125.5 19.5 20.4 61.4 40.3 43.3 19.3 67.7 20.8 56.2 74.2 46.3 37.3 56.1 116.0 49.8 86.8 63.9 18.2 63.8 58.7 22.1 19.5 116.8 102.3 73.4 112.8 59.3 43.0 26.1 450.1 118.6 330.9 276.6 68.9 118.4 184.2 347.4 210.9 338.9 457.1 190.7 165.5 504.2 390.2 181.8 269.1 251.1 260.7 196.2 591.3 346.5 221.3 305.7 179.9 260.0 70.3 499.2 238.2 58.2 98.1 238.2 198.2 164.7 170.9 188.1 392.9 0.6 236.5 156.2 380.3 222.1 208.6 177.4 131.8 471.7 459.7 299.8 184.2 239.6 196.1 183.8 328.9 290.5 224.6 218.4 277.8 212.7 168.7 382.7 220.0 223.9 474.1 32.4 77.0 540.3 95.0 251.3 380.8 116.2 78.2 41.8 69.6 74.9 83.1 66.3 72.5 78.0 72.9 56.1 55.6 55.7 93.4 70.9 92.9 49.0 75.2 67.8 17.3 20.1 29.6 25.4 17.3 18.3 19.5 20.4 20.8 18.2 19.5 26.1 149.7 121.8 130.8 16.3 126.2 271.2 189.8 128.8 146.3 70.3 143.3 161.3 218.8 161.5 112.0 79.1 81.3 284.2 174.5 156.7 82.2 172.0 17.4 118.8 157.7 156.6 88.5 448.8 10.4 173.1 235.4 159.6 85.1 170.6 111.2 195.1 105.7 125.1 190.9 26.9 18.6 188.1 67.1 185.3 300.7 26.2 189.5 219.1 101.4 31.9 263.3 136.2 212.1 26.2 37.1 136.9 117.3 191.5 44.0 252.9 140.0 129.5 89.0 138.8 210.4 189.1 197.0 87.2 220.7 169.9 233.6 108.6 189.1 138.6 232.5 209.2 DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13020.7;intestine: 8627.2;skeletal muscle: 16532.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2531.9" "Cancer enhanced" "Detected in all" "prostate cancer: 562.1;stomach cancer: 400.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 70.2;LHCN-M2: 145.3;NB-4: 39.5;RH-30: 333.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 29.5" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB000034: , HPA018803: AB_1847616" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "unprognostic (3.43e-2)" "unprognostic (8.76e-2)" "unprognostic (7.75e-3)" "unprognostic (6.61e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (4.67e-1)" "unprognostic (3.84e-2)" "unprognostic (2.57e-1)" "unprognostic (7.43e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (3.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (9.25e-3)" 235.3 57.1 2.1 436.2 4.9 1.1 51.2 2.1 9.6 504.3 5.0 8627.2 291.3 3015.2 86.0 1481.2 1085.0 452.1 13020.7 2.4 2.5 37.6 15.5 173.9 7.2 3.4 2.5 171.8 14.6 0.5 8.4 52.7 2.4 2218.8 245.6 0.0 255.3 2253.1 16532.0 152.4 1343.5 2557.5 2.1 25.2 1965.6 16.1 2.6 3.2 66.2 5753.8 1.2 4761.8 669.4 2.4 0.0 0.0 0.1 0.0 0.0 2.2 5.3 0.2 0.0 0.1 0.1 0.5 0.0 0.0 9.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 17.0 0.1 1.3 70.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 145.3 0.0 0.0 39.5 0.5 0.0 0.0 0.0 333.1 2.1 0.0 0.0 0.2 1.2 0.0 0.0 0.0 9.2 0.0 5.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.1 4.9 2.1 9.6 2.4 2.5 3.4 2.5 2.4 2.1 2.6 2.4 0.4 0.0 0.0 0.0 0.0 4.1 2.7 0.0 0.0 0.0 0.1 0.0 2531.9 1.5 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 90.6 0.5 6.7 22.7 0.0 0.0 0.1 0.0 5.2 104.6 0.0 0.1 0.0 0.0 1.8 0.0 5.6 0.0 0.0 0.9 0.0 0.0 10.7 71.6 28.9 2.8 12.4 0.0 0.6 0.0 0.0 0.5 0.0 0.5 0.0 50.4 0.0 8.7 0.0 0.1 0.0 0.0 46.0 497.8 210.5 5.0 5.1 0.1 9.8 8.5 2.4 0.0 0.2 2.9 DHFR ENSG00000228716 "Dihydrofolate reductase" P00374 5 80626226-80654983 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methotrexate resistance, One-carbon metabolism" "Oxidoreductase, RNA-binding" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.8;Spermatocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037129, HPA051465" Uncertain Approved Mitochondria NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "CAB037129: AB_439683, HPA051465: AB_2681494" "unprognostic (1.44e-2)" "unprognostic (1.03e-2)" "unprognostic (2.24e-3)" "unprognostic (2.91e-3)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (2.83e-2)" "unprognostic (2.35e-2)" "unprognostic (2.02e-2)" "unprognostic (4.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (1.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" 25.2 5.3 15.3 20.7 16.5 54.3 12.0 15.8 21.9 8.0 13.3 21.4 24.5 8.6 7.0 14.1 7.4 8.5 7.2 13.8 15.5 21.3 60.1 7.5 41.5 16.6 16.6 6.6 3.2 9.1 6.3 14.4 16.6 8.9 25.3 10.3 6.8 9.5 19.6 9.8 25.1 12.0 16.5 10.3 12.2 18.5 15.8 60.7 8.2 25.8 39.5 10.3 5.7 17.7 98.1 66.6 164.8 122.7 30.7 32.0 60.6 76.5 58.1 130.2 149.0 63.8 114.6 196.9 32.5 44.6 106.0 67.0 214.4 98.6 208.5 88.2 132.1 94.8 104.5 59.5 6.6 111.7 40.3 22.3 9.9 116.9 13.0 22.2 63.9 142.0 108.3 146.7 133.5 98.2 276.5 44.9 83.6 48.3 38.5 176.7 323.3 194.1 75.1 61.5 134.3 93.7 107.9 49.9 54.6 83.5 98.5 108.6 38.5 41.0 62.0 116.0 148.3 68.2 146.6 210.3 91.5 222.1 107.7 0.2 0.3 0.2 0.5 0.6 0.2 0.5 0.6 0.8 0.5 0.5 0.5 0.6 0.8 0.5 0.5 0.8 0.9 0.6 15.3 16.5 15.8 21.9 13.8 15.5 16.6 16.6 16.6 16.5 15.8 17.7 4.1 6.4 11.7 4.9 21.4 6.9 6.5 6.0 4.0 3.5 8.9 8.9 13.0 4.3 6.1 14.7 2.1 35.2 7.4 19.3 9.8 7.4 7.4 10.8 7.7 7.7 4.9 145.8 7.3 3.7 47.3 12.0 11.7 8.0 2.5 22.0 10.0 48.3 44.7 3.3 7.2 19.1 4.1 18.9 4.4 6.4 14.0 12.8 0.0 4.7 7.1 14.5 13.4 3.5 6.0 4.7 10.3 16.1 60.9 2.9 26.6 40.0 6.9 3.2 13.1 9.0 12.5 132.2 49.8 21.2 5.5 13.3 11.8 12.3 38.1 12.1 DHX9 "DDX9, LKP, RHA" ENSG00000135829 "DExH-box helicase 9" Q08211 1 182839347-182887982 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA replication, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, mRNA processing, mRNA splicing, mRNA transport, RNA-mediated gene silencing, Transcription, Transcription regulation, Transcription termination, Translation regulation, Transport" "Activator, DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011819, HPA028050, HPA055684" Supported Supported Nucleoplasm,Nucleoli NA NA 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Nucleoli "CAB011819: AB_777725, HPA028050: AB_10603564, HPA055684: AB_2682885" "unprognostic (8.14e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-2)" "unprognostic (4.80e-2)" "unprognostic (1.58e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (3.17e-4)" "unprognostic (9.98e-2)" "prognostic unfavorable (6.04e-4)" "unprognostic (2.76e-1)" "unprognostic (2.88e-2)" "unprognostic (5.53e-2)" "unprognostic (7.51e-2)" "unprognostic (1.43e-1)" "unprognostic (1.70e-1)" "unprognostic (3.17e-1)" "unprognostic (1.99e-1)" 38.7 30.5 13.6 47.4 15.8 131.4 53.2 19.0 19.7 43.7 17.0 40.2 32.6 49.4 33.0 32.2 45.9 31.1 28.5 13.1 16.0 49.9 36.9 38.6 56.9 15.2 13.6 52.8 30.5 68.2 21.1 44.6 16.3 39.6 47.1 66.5 32.5 44.3 30.3 31.1 36.3 50.8 16.6 40.9 34.5 50.4 14.6 88.7 48.0 37.7 70.2 54.0 30.0 25.5 165.7 158.8 223.0 122.3 113.7 87.8 219.2 143.5 130.3 203.6 137.0 175.8 124.2 264.3 133.7 129.6 121.7 138.8 342.6 155.2 225.7 108.3 169.5 176.4 121.0 119.6 62.5 258.3 115.0 78.6 75.8 200.4 53.4 91.6 161.7 132.9 281.8 91.9 165.1 142.3 263.6 61.1 282.8 173.9 96.8 236.0 208.0 151.0 127.0 187.8 160.0 183.2 203.2 125.0 83.2 186.4 148.4 140.9 127.6 125.3 138.8 128.9 195.9 93.6 167.2 305.0 79.0 137.0 174.5 7.7 21.3 16.1 23.4 22.5 26.2 20.5 19.8 21.1 29.9 16.6 21.6 23.7 8.0 20.0 19.7 14.2 20.1 21.2 13.6 15.8 19.0 19.7 13.1 16.0 15.2 13.6 16.3 16.6 14.6 25.5 43.6 41.7 74.1 59.1 54.5 53.7 61.2 42.7 38.7 59.6 43.3 38.9 43.9 30.0 60.8 51.5 52.1 50.9 70.2 38.6 19.6 49.0 26.8 79.2 67.4 50.7 53.8 74.5 49.4 50.8 47.5 48.0 37.8 109.8 44.9 67.7 36.0 28.0 40.8 28.6 55.5 40.9 30.5 35.4 35.1 45.8 60.3 44.7 30.2 55.3 55.9 42.7 42.2 55.3 70.3 52.3 28.0 47.0 52.4 48.3 35.4 38.0 67.7 77.1 39.5 73.9 54.1 69.9 68.2 51.7 47.2 49.5 59.2 60.9 54.4 55.4 DIAPH1 "DFNA1, hDIA1, LFHL1" ENSG00000131504 "Diaphanous related formin 1" O60610 5 141515016-141619055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing Actin-binding "Cancer-related genes, Deafness, Disease variant, Epilepsy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 172.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 564.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004916, HPA076913" Approved Uncertain "Plasma membrane,Cytosol" NA NA 2000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA004916: AB_1847668, HPA076913: " "unprognostic (6.79e-2)" "unprognostic (2.99e-1)" "unprognostic (2.12e-3)" "unprognostic (3.73e-2)" "unprognostic (4.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (4.54e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (7.81e-5)" "unprognostic (2.88e-3)" "prognostic favorable (1.29e-5)" "unprognostic (1.64e-2)" "unprognostic (1.84e-2)" "unprognostic (7.00e-2)" "unprognostic (1.65e-1)" 27.9 20.3 21.0 42.1 22.5 90.2 24.2 18.3 20.9 24.4 40.0 31.0 40.6 18.5 44.3 58.0 25.2 30.0 34.9 21.5 25.7 38.1 91.7 51.3 67.0 18.8 19.9 12.9 37.3 44.6 24.5 25.1 20.1 14.7 31.1 28.4 36.1 19.3 172.0 47.3 36.5 18.7 18.0 36.3 45.1 19.9 27.4 68.5 33.1 55.7 66.4 47.1 30.4 18.6 147.8 92.6 53.2 68.4 40.4 54.5 71.3 59.5 62.2 67.7 70.2 318.1 131.6 156.5 88.1 85.5 103.0 157.9 116.9 191.5 84.8 88.9 66.6 282.6 121.4 103.6 37.7 198.9 564.7 34.4 102.1 94.5 95.5 30.5 87.0 234.8 101.2 106.9 67.7 141.5 217.2 256.8 51.6 75.2 61.6 240.1 87.1 87.6 129.8 158.5 69.4 37.3 146.2 184.6 59.5 47.5 77.5 92.1 52.8 93.9 49.9 52.1 119.9 54.2 94.4 111.7 50.2 153.7 57.8 23.6 12.8 29.8 32.6 14.0 21.2 9.3 20.3 25.3 12.6 9.1 14.8 23.9 13.7 13.7 15.1 10.0 18.7 15.4 21.0 22.5 18.3 20.9 21.5 25.7 18.8 19.9 20.1 18.0 27.4 18.6 33.9 48.1 46.8 11.8 40.0 52.6 60.8 22.4 21.6 17.3 35.1 23.1 18.6 22.8 48.0 44.1 54.2 20.9 96.9 60.5 5.9 62.7 27.9 42.3 18.9 39.0 5.4 52.6 44.1 98.0 31.9 25.9 76.0 83.0 46.9 14.5 16.8 91.6 17.1 6.7 33.6 23.1 12.2 38.4 60.6 9.0 11.8 78.5 19.6 24.4 54.6 12.1 115.4 25.6 9.1 122.9 35.7 10.9 54.1 77.3 35.2 13.9 30.4 69.0 13.1 15.4 26.4 18.3 26.1 38.7 59.7 52.1 92.8 18.3 30.1 91.2 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DICER1 "Dicer, HERNA, K12H4.8-LIKE, KIAA0928, MNG1" ENSG00000100697 "Dicer 1, ribonuclease III" Q9UPY3 14 95086228-95158010 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing" "Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 418.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000694, CAB068185" Approved Supported Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB068185: AB_2665650, HPA000694: AB_1078661" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (1.21e-1)" "unprognostic (1.72e-1)" "unprognostic (6.75e-2)" "unprognostic (9.62e-2)" "unprognostic (1.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.21e-1)" "unprognostic (8.52e-3)" "unprognostic (5.73e-2)" "unprognostic (9.22e-2)" "unprognostic (4.22e-2)" "unprognostic (9.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.04e-3)" "unprognostic (3.74e-2)" 15.6 7.9 6.7 14.0 22.5 10.8 15.1 12.3 11.4 13.3 7.4 13.0 7.5 12.7 8.3 15.0 12.4 8.7 9.9 7.2 14.0 10.7 12.8 14.9 11.0 19.1 16.0 14.3 12.6 11.5 10.6 18.7 18.5 12.5 10.9 19.3 12.4 10.1 19.2 13.0 11.6 11.5 11.6 12.1 10.1 13.2 20.3 8.5 14.7 16.2 12.0 12.7 14.5 39.4 18.6 19.4 40.7 12.0 7.2 14.5 26.4 15.5 10.7 11.3 11.1 25.4 12.5 20.9 16.1 16.0 10.4 21.2 31.6 13.9 20.5 35.9 14.6 36.5 10.1 16.0 6.7 22.6 18.0 12.2 10.1 12.3 20.8 8.0 16.1 15.7 15.7 16.6 16.9 21.8 24.1 6.8 9.3 11.0 10.2 16.0 31.9 12.2 8.2 30.9 31.9 16.4 16.2 13.4 15.2 19.2 18.0 12.4 16.4 8.1 14.4 14.0 16.9 18.9 31.7 31.4 8.0 14.5 13.1 1.4 1.1 0.8 0.3 1.4 0.7 0.7 0.6 0.4 0.8 0.7 0.5 0.3 3.9 0.5 3.2 0.4 0.7 0.4 6.7 22.5 12.3 11.4 7.2 14.0 19.1 16.0 18.5 11.6 20.3 39.4 69.4 54.5 53.7 88.8 45.7 27.4 49.5 29.9 40.5 98.2 50.7 29.1 36.4 41.5 47.3 46.0 56.3 46.6 36.9 44.0 5.9 33.4 23.3 37.4 54.2 52.0 46.1 33.4 99.7 23.1 22.8 45.6 33.1 50.1 12.0 35.5 42.1 60.1 48.8 107.7 112.2 29.7 24.4 104.2 24.8 15.5 54.3 82.3 23.2 81.5 84.6 33.5 33.0 109.1 418.6 33.2 28.0 52.6 39.2 62.5 27.1 25.9 38.6 73.8 32.9 64.3 41.9 45.5 56.1 63.0 27.6 25.7 31.7 35.9 33.9 62.1 DIS3 "dis3p, EXOSC11, KIAA1008, RRP44" ENSG00000083520 "DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease" Q9Y2L1 13 72752169-72782096 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "rRNA processing" "Endonuclease, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 169.2;Late spermatids: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039281, HPA058762" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "HPA039281: AB_10795583, HPA058762: AB_2683810" "unprognostic (1.61e-1)" "unprognostic (1.52e-1)" "unprognostic (1.18e-1)" "unprognostic (8.97e-2)" "unprognostic (8.14e-2)" "unprognostic (1.51e-2)" "unprognostic (1.49e-1)" "unprognostic (2.84e-1)" "unprognostic (6.38e-2)" "unprognostic (8.68e-2)" "unprognostic (1.32e-3)" "unprognostic (3.35e-3)" "unprognostic (1.02e-1)" "unprognostic (2.37e-2)" "unprognostic (3.69e-2)" "unprognostic (7.88e-2)" "unprognostic (1.03e-1)" 13.8 9.9 5.3 12.4 5.7 20.4 15.8 9.1 6.7 11.3 7.1 10.0 8.5 11.2 11.5 12.4 9.9 10.4 11.6 5.2 5.9 12.8 16.6 11.4 17.6 5.2 5.6 13.4 8.9 11.9 8.9 12.0 5.3 12.3 10.9 12.1 9.4 10.5 10.2 11.1 9.9 11.0 5.5 12.2 9.9 21.3 6.3 14.1 15.0 10.4 17.3 14.1 10.8 6.9 29.5 13.4 25.9 21.9 26.9 31.9 17.0 25.5 31.0 25.6 31.1 20.7 23.8 35.6 21.6 26.3 16.2 23.8 35.7 29.4 40.9 29.3 26.3 41.8 27.8 18.7 33.4 71.4 23.2 33.4 20.1 29.0 37.9 25.5 27.8 26.6 28.3 14.4 31.4 10.3 30.5 34.8 24.3 44.7 15.7 24.2 19.7 16.2 25.4 23.2 23.3 30.8 20.9 17.3 25.4 26.8 16.7 32.1 26.1 15.4 12.5 17.5 27.4 27.6 33.2 28.0 42.9 33.2 22.7 8.4 3.6 5.2 4.0 6.3 5.6 4.2 5.0 4.5 4.3 3.7 4.9 4.5 2.1 6.9 5.2 2.7 6.7 3.2 5.3 5.7 9.1 6.7 5.2 5.9 5.2 5.6 5.3 5.5 6.3 6.9 51.6 35.3 37.2 12.4 35.3 25.5 36.5 24.5 18.2 38.8 27.6 26.4 27.6 21.5 40.2 9.2 29.2 23.8 45.0 19.0 23.5 21.7 169.2 26.2 37.6 41.2 30.5 18.7 21.5 20.1 23.5 33.3 19.9 45.6 33.6 26.3 26.7 23.7 14.4 32.0 24.0 17.2 18.3 19.2 13.8 135.5 28.9 21.4 12.4 24.4 38.2 23.6 25.7 17.6 24.2 25.4 8.1 28.2 30.2 27.4 16.3 17.2 35.4 41.6 6.6 58.3 27.0 28.9 37.7 31.4 31.3 22.6 33.7 29.1 21.2 53.9 DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Alveolar cells type 2: 225.9;Excitatory neurons: 208.8;Microglial cells: 317.6;Oligodendrocyte precursor cells: 244.3;Oligodendrocytes: 707.2;Sertoli cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 83.2;U-2197: 98.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017753 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" Nucleoplasm "HPA017753: AB_10600805" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.11e-4)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (8.46e-3)" "unprognostic (6.49e-2)" "unprognostic (2.02e-2)" "unprognostic (3.56e-3)" "unprognostic (2.79e-2)" "unprognostic (7.33e-2)" "unprognostic (1.67e-1)" 52.5 10.6 17.8 8.8 28.7 2.6 29.6 21.8 18.2 13.5 4.8 19.6 5.6 16.1 5.3 6.3 14.7 19.1 21.5 22.9 21.3 13.7 20.4 42.9 3.8 27.8 23.5 9.5 9.0 6.1 5.3 24.2 29.0 6.7 6.2 1.5 5.6 4.2 7.2 7.1 11.5 19.1 18.8 16.4 13.6 4.0 22.5 2.1 15.7 10.3 1.8 15.4 11.1 38.0 0.1 0.7 6.6 0.0 69.4 35.5 20.3 39.3 33.7 40.7 48.6 11.5 6.6 0.0 9.7 51.4 39.4 6.6 4.3 7.4 83.2 0.0 7.2 39.5 0.1 21.7 31.8 0.0 13.7 36.6 0.6 62.6 46.7 43.3 46.7 0.1 2.7 0.0 33.6 0.8 0.0 0.0 0.7 1.4 4.7 0.0 0.0 0.0 19.7 24.4 0.0 2.9 0.0 1.1 31.8 27.4 0.0 0.0 61.7 45.5 18.8 98.7 15.3 0.1 0.0 0.0 31.6 0.3 63.4 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.8 28.7 21.8 18.2 22.9 21.3 27.8 23.5 29.0 18.8 22.5 38.0 171.7 250.0 225.9 177.3 2.3 14.8 2.5 4.8 5.2 0.9 9.3 8.3 37.8 24.3 19.7 3.7 0.0 7.8 0.6 0.4 1.9 3.1 8.4 15.3 36.1 138.4 1.2 25.2 208.8 4.4 2.3 74.2 4.6 27.3 68.2 0.1 193.1 25.7 3.6 13.5 151.8 1.2 0.0 18.6 17.0 4.3 72.4 6.2 24.9 317.6 0.2 1.0 0.0 244.3 707.2 3.0 1.3 36.1 1.9 1.4 6.1 1.9 3.0 1.9 223.5 50.0 138.0 6.2 11.4 1.8 9.2 2.7 3.6 31.1 2.9 1.7 DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 452.8;Excitatory neurons: 1275.8;Inhibitory neurons: 719.8;Oligodendrocyte precursor cells: 1161.6;Oligodendrocytes: 610.2;Rod photoreceptor cells: 375.9" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 7 "B-cells: 1.1;granulocytes: 4.3" "Cell line enhanced" "Detected in many" "AF22: 27.9;Hep G2: 30.3;RH-30: 25.0;SuSa: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" 16.3 14.7 11.8 5.3 12.5 0.6 16.8 0.2 14.2 7.1 7.1 38.0 5.4 18.1 11.2 9.1 16.8 21.5 37.8 15.5 0.5 5.4 50.0 7.2 4.7 1.1 0.6 13.9 52.9 4.3 4.4 15.1 0.4 13.4 8.4 80.0 30.2 30.7 73.4 11.5 9.4 22.0 0.0 2.3 15.5 8.3 4.8 3.3 7.3 67.4 6.4 21.1 7.2 9.9 0.3 0.2 27.9 0.3 0.3 0.3 7.6 6.1 0.6 2.8 3.1 13.3 0.6 0.4 0.2 12.5 2.3 8.5 10.5 15.0 4.2 7.4 8.6 3.3 10.5 30.3 14.7 1.2 3.7 3.3 9.5 4.6 17.1 15.3 6.1 2.0 2.9 0.4 8.3 0.5 4.4 0.6 13.3 0.1 9.8 0.3 25.0 0.1 0.3 3.3 0.5 8.5 0.1 2.3 2.8 27.7 2.2 0.1 1.6 0.3 0.5 1.1 4.6 0.4 23.8 0.6 1.0 2.3 14.4 0.8 0.1 2.0 0.1 0.1 0.1 1.1 0.1 0.1 0.3 0.9 0.1 0.1 4.3 0.1 0.1 0.4 0.2 0.1 11.8 12.5 0.2 14.2 15.5 0.5 1.1 0.6 0.4 0.0 4.8 9.9 8.5 28.9 25.3 164.9 6.7 20.1 7.0 6.3 3.4 78.0 26.5 50.0 452.8 7.2 15.0 3.7 308.6 33.7 0.7 0.8 3.9 3.8 22.4 22.5 1.4 9.9 8.4 0.0 1275.8 12.3 9.5 26.1 3.6 5.6 1.3 37.9 6.1 49.8 4.2 11.8 719.8 1.3 6.1 4.8 5.4 20.5 89.2 3.5 19.6 94.6 6.7 54.9 0.0 1161.6 610.2 6.0 0.1 118.8 0.2 3.6 3.6 2.1 60.4 375.9 118.3 95.2 50.3 4.0 8.8 1.8 11.5 5.1 1.0 33.1 4.2 4.8 DNAH12 "DHC3, DLP12, DNAH12L, DNAH7L, Dnahc3, DNHD2, FLJ40427, FLJ44290, hdhc3, HL-19" ENSG00000174844 "Dynein axonemal heavy chain 12" Q6ZR08 3 57293699-57544344 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 5.0;choroid plexus: 7.1;fallopian tube: 10.3;lung: 3.5;testis: 8.9" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 230.5;Respiratory ciliated cells: 318.9" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 9.6" "HPA037493, HPA058203, HPA061365" Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA037493: AB_10671758, HPA058203: AB_2683637, HPA061365: AB_2684493" "unprognostic (4.85e-2)" "unprognostic (1.29e-2)" "unprognostic (2.23e-1)" "unprognostic (2.18e-3)" "unprognostic (2.96e-2)" "unprognostic (2.17e-1)" "unprognostic (2.80e-2)" "unprognostic (1.51e-3)" "unprognostic (3.06e-2)" "unprognostic (3.21e-1)" "unprognostic (4.40e-2)" "unprognostic (5.90e-2)" "unprognostic (3.43e-5)" "unprognostic (2.82e-2)" "unprognostic (1.34e-1)" "unprognostic (2.53e-2)" "unprognostic (5.47e-2)" 0.0 0.2 1.2 0.0 1.0 0.0 0.2 0.7 0.7 0.9 7.1 0.0 0.0 0.3 0.1 0.0 10.3 0.2 0.0 1.3 1.3 0.1 0.1 3.5 0.0 4.5 5.0 0.1 0.7 0.0 0.9 0.0 2.9 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 2.8 0.0 0.1 8.9 1.2 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 1.0 0.7 0.7 1.3 1.3 4.5 5.0 2.9 2.8 1.2 1.6 0.2 3.2 1.1 13.7 0.2 0.0 0.2 5.4 0.0 0.3 0.8 0.6 1.1 0.0 42.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 49.8 230.5 1.3 0.1 1.8 0.0 3.9 0.0 0.0 1.2 0.0 4.6 1.3 0.3 0.0 0.0 0.1 0.0 3.8 0.0 6.1 0.0 0.0 9.8 0.9 0.7 0.0 2.8 0.1 1.7 0.0 5.0 15.8 0.1 0.0 0.4 0.0 0.1 0.0 0.5 318.9 0.2 0.0 0.7 1.6 28.4 2.7 0.0 0.0 0.0 0.5 5.4 0.1 0.1 DNAJB1 "Hsp40, HSPF1, RSPH16B, Sis1" ENSG00000132002 "DnaJ heat shock protein family (Hsp40) member B1" P25685 19 14514769-14560391 "Cancer-related genes, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1705.1" "Cell type enhanced" "Detected in all" "Langerhans cells: 1392.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 1705.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017450, HPA063247" Enhanced Supported Nucleoplasm NA Yes 23000 "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB017450: AB_10631418, HPA063247: AB_2684971" "unprognostic (3.75e-2)" "unprognostic (2.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (1.60e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.74e-2)" "unprognostic (3.83e-1)" "unprognostic (1.85e-1)" "unprognostic (7.91e-3)" "unprognostic (2.17e-1)" "prognostic favorable (5.96e-4)" "unprognostic (2.20e-2)" "unprognostic (4.44e-2)" "unprognostic (2.00e-2)" "unprognostic (6.77e-2)" 206.0 216.1 228.5 40.9 241.7 133.8 62.0 320.9 1705.1 188.1 259.4 86.7 35.2 54.0 40.8 439.9 75.3 183.7 182.8 243.8 240.2 245.0 230.3 286.0 42.0 250.4 251.8 231.9 89.8 66.4 148.4 123.4 285.4 73.9 48.4 81.2 109.7 127.1 51.2 128.5 62.7 54.5 240.6 104.5 149.1 149.4 241.8 107.3 97.2 208.0 76.5 133.6 257.7 323.4 192.5 212.5 80.8 81.7 146.8 114.1 45.6 125.9 99.9 210.4 158.8 126.3 106.7 54.8 135.4 121.0 135.5 144.9 169.1 96.7 150.3 55.0 76.1 86.7 115.0 275.6 94.6 57.9 78.5 61.0 237.5 85.3 73.4 114.7 71.6 35.7 131.2 471.6 123.6 130.5 102.2 60.1 80.4 285.9 228.3 73.7 106.3 121.7 101.8 62.4 67.0 51.1 121.1 233.7 127.1 90.8 60.3 60.6 64.7 156.4 98.0 184.1 264.8 193.5 141.7 65.7 114.4 109.2 151.1 68.8 92.4 116.2 171.6 159.0 184.8 93.7 244.5 214.9 76.0 92.0 281.6 219.9 137.6 125.1 172.2 45.1 270.9 322.6 228.5 241.7 320.9 1705.1 243.8 240.2 250.4 251.8 285.4 240.6 241.8 323.4 750.2 157.0 95.4 32.3 248.7 425.8 1142.1 148.0 719.3 60.9 468.8 476.4 367.1 72.9 118.6 23.9 118.9 135.6 214.2 459.6 41.1 132.8 491.8 374.8 339.3 397.3 407.3 60.0 10.2 162.6 199.3 661.2 408.7 552.8 339.4 100.2 86.7 59.9 158.1 52.2 8.9 420.1 81.4 85.1 1392.1 475.3 63.3 559.3 503.4 23.4 31.3 160.7 25.7 3.0 16.5 123.8 380.7 36.9 697.0 461.1 117.3 59.1 138.0 164.7 26.3 398.9 673.3 290.2 53.4 1186.0 478.9 274.9 948.4 104.8 393.7 606.2 DNAJC2 "MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin" ENSG00000105821 "DnaJ heat shock protein family (Hsp40) member C2" Q99543 7 103312289-103344830 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chaperone, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 248.5;Spermatocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020454 Approved Supported Cytosol NA Yes "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA020454: AB_1859492" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (2.20e-2)" "unprognostic (1.11e-1)" "unprognostic (7.71e-2)" "unprognostic (2.13e-3)" "unprognostic (2.13e-3)" "unprognostic (1.63e-2)" "unprognostic (5.35e-2)" "unprognostic (2.21e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.11e-1)" "unprognostic (2.30e-1)" "unprognostic (3.51e-1)" "unprognostic (3.28e-1)" 15.7 13.4 10.2 12.2 10.7 42.0 13.4 12.7 19.2 13.1 10.5 11.9 14.7 12.8 9.7 13.8 12.1 9.8 13.5 10.5 10.4 16.4 15.7 11.2 16.8 10.0 10.7 15.7 13.4 9.0 12.6 11.9 10.3 12.3 11.9 8.7 12.6 7.7 32.5 13.6 11.9 7.4 9.3 12.2 12.9 31.3 11.4 12.3 12.7 12.7 13.2 18.8 12.8 11.8 52.7 38.1 21.4 38.7 16.1 22.6 41.6 35.1 25.8 38.5 28.6 52.9 37.2 74.9 53.7 24.4 55.2 35.5 57.5 25.7 58.4 40.6 43.4 55.1 38.7 47.3 28.6 97.9 41.2 19.6 21.9 44.9 39.4 16.2 25.6 27.8 128.3 46.2 32.0 83.8 95.0 102.1 75.9 56.8 57.0 59.7 43.0 70.1 22.8 24.8 40.6 38.7 47.7 66.2 39.7 39.6 28.1 49.8 30.8 37.5 59.9 83.3 68.1 48.9 67.8 146.0 27.3 97.9 47.6 61.3 9.0 9.3 10.9 10.3 12.1 11.7 10.9 11.7 9.4 13.7 12.5 12.5 3.6 16.4 15.3 11.2 12.8 5.9 10.2 10.7 12.7 19.2 10.5 10.4 10.0 10.7 10.3 9.3 11.4 11.8 31.3 25.6 47.0 10.7 46.1 64.6 78.7 37.3 35.3 27.1 26.3 36.6 32.3 22.8 50.2 22.0 41.7 43.7 45.9 31.1 35.2 45.0 248.5 43.8 50.1 39.6 35.3 29.9 24.7 46.0 75.5 41.0 42.8 44.2 53.7 50.1 18.5 30.6 39.6 21.9 17.9 39.0 26.4 24.5 41.3 37.3 39.4 37.8 19.6 13.1 42.9 19.3 44.3 24.1 20.6 50.2 32.9 31.2 36.9 79.2 36.4 31.0 43.4 29.0 39.5 63.7 64.8 238.7 131.9 33.5 62.1 55.4 43.2 58.3 51.9 91.5 DNER "bet, UNQ26" ENSG00000187957 "Delta/notch like EGF repeat containing" Q8NFT8 2 229357629-229714555 "Cancer-related genes, Predicted membrane proteins" "Notch signaling pathway" "Activator, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 73.0;brain: 147.5;choroid plexus: 143.8" "Group enriched" "Detected in many" 4 "Bipolar cells: 123.3;Inhibitory neurons: 333.0;Oligodendrocyte precursor cells: 435.8;Oligodendrocytes: 247.7" "Cancer enriched" "Detected in many" 32 "glioma: 73.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "GAMG: 368.0;hTERT-HME1: 149.7;hTERT-RPE1: 409.5;U-138 MG: 252.2;U-87 MG: 149.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017320 Enhanced NA NA 7900000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017320: AB_1847808" "unprognostic (4.39e-2)" "unprognostic (1.83e-1)" "unprognostic (3.25e-1)" "unprognostic (1.00e-3)" "unprognostic (8.73e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.23e-3)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.42e-4)" "unprognostic (2.59e-2)" "unprognostic (7.32e-2)" "unprognostic (5.63e-2)" "unprognostic (5.13e-3)" 2.0 73.0 88.3 1.3 121.0 0.0 2.3 139.7 82.9 2.0 143.8 5.2 0.4 2.8 5.7 0.3 4.1 0.2 11.8 72.3 130.9 11.2 0.1 1.0 0.3 121.3 121.0 0.6 0.9 8.9 30.3 0.4 117.8 1.9 1.1 60.5 43.4 0.4 0.8 10.3 1.6 1.2 124.7 0.1 10.7 1.0 147.5 0.5 0.1 0.5 1.2 0.8 1.1 137.2 0.4 1.9 3.9 0.3 0.6 0.5 0.0 0.2 1.4 8.6 2.6 0.0 1.1 0.0 0.4 0.1 368.0 0.1 0.3 1.2 4.3 0.0 0.1 0.0 12.4 0.0 1.4 0.0 0.1 2.6 9.3 6.5 149.7 409.5 0.0 0.0 0.0 0.3 2.3 0.1 0.0 0.0 2.5 0.2 14.0 0.1 1.6 0.0 14.6 0.0 30.3 2.5 0.8 0.1 0.8 0.4 0.1 0.0 0.0 252.2 0.0 8.5 39.7 0.0 0.0 0.0 149.6 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 88.3 121.0 139.7 82.9 72.3 130.9 121.3 121.0 117.8 124.7 147.5 137.2 0.1 0.0 0.0 68.9 0.0 0.4 5.9 1.9 1.8 123.3 1.6 0.6 12.2 0.0 1.4 3.7 14.6 0.0 0.0 0.0 1.9 0.2 7.3 4.1 1.5 0.6 28.7 0.0 24.1 1.3 0.2 4.3 0.0 6.7 0.0 1.6 0.0 0.0 0.1 11.8 333.0 0.0 6.1 0.0 0.8 1.9 5.9 0.9 19.6 8.4 0.1 52.0 0.0 435.8 247.7 0.3 0.0 6.0 0.0 4.5 0.0 1.2 34.1 55.0 0.0 0.1 0.8 1.2 1.1 0.5 0.0 0.1 0.2 0.6 0.1 0.5 DNM2 "CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII" ENSG00000079805 "Dynamin 2" P50570 19 10718079-10833488 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Phagocytosis" "Hydrolase, Motor protein" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 242.8;Paneth cells: 177.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054246 Supported Approved "Golgi apparatus,Cytosol" NA NA 230000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Cytosol" "HPA054246: AB_2682427" "unprognostic (2.30e-1)" "unprognostic (5.23e-2)" "unprognostic (4.72e-2)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "prognostic favorable (8.91e-4)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.03e-1)" "unprognostic (3.79e-1)" "unprognostic (1.89e-1)" "unprognostic (4.75e-2)" "unprognostic (5.35e-2)" "unprognostic (5.47e-2)" "unprognostic (5.40e-3)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (1.99e-3)" 55.1 69.9 50.5 63.2 77.8 125.7 46.1 74.1 64.1 49.0 38.8 105.8 65.9 42.2 25.3 67.6 42.5 40.5 87.2 52.3 57.4 72.8 57.2 87.0 62.4 82.7 78.9 36.6 68.2 38.9 41.9 51.3 79.8 47.4 83.9 30.7 55.0 55.7 108.1 92.8 99.6 35.1 60.3 81.0 98.6 55.1 72.9 58.6 47.6 82.8 65.4 64.6 54.5 101.6 116.4 92.8 67.6 54.6 67.6 65.4 86.5 75.1 70.5 108.8 91.7 94.2 74.7 83.2 132.2 81.5 52.5 99.4 92.6 82.1 90.8 103.1 72.4 160.1 81.7 107.1 82.9 87.8 146.5 67.8 62.4 83.5 77.9 66.2 107.3 84.9 131.5 139.1 68.0 140.1 126.3 85.7 76.6 138.3 109.7 125.6 72.6 95.7 71.3 171.1 97.1 63.8 86.6 73.6 54.2 74.9 58.8 106.2 99.6 120.7 40.5 172.0 102.7 112.7 127.3 77.9 89.9 134.0 61.0 3.5 3.5 7.0 4.0 6.2 3.8 2.5 3.0 4.4 4.2 2.1 1.7 3.0 6.5 8.9 8.4 8.4 3.8 4.1 50.5 77.8 74.1 64.1 52.3 57.4 82.7 78.9 79.8 60.3 72.9 101.6 37.8 32.1 22.3 24.8 48.8 23.2 17.1 13.8 22.2 28.8 19.7 16.3 30.3 14.3 25.7 51.5 22.9 25.7 57.2 242.8 50.9 35.2 48.4 32.2 17.9 33.1 21.6 38.1 29.2 32.0 106.9 19.5 168.7 39.7 19.0 36.8 20.3 22.8 49.1 43.7 31.1 106.9 14.2 28.0 39.6 98.0 16.8 55.2 19.6 60.9 43.4 17.2 39.1 23.1 90.9 45.2 177.3 27.8 92.2 20.2 90.7 38.8 18.0 26.3 26.3 18.7 27.6 15.0 12.3 26.6 31.5 31.7 46.4 40.7 82.5 22.8 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 127.2;Horizontal cells: 95.9;Rod photoreceptor cells: 143.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 59.6;REH: 59.5;SH-SY5Y: 71.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 5.6 9.0 8.9 9.8 12.6 8.7 6.2 9.3 10.7 9.1 2.4 11.3 6.7 9.3 8.7 6.0 7.5 6.3 5.9 8.8 7.9 11.3 5.3 7.3 11.1 9.0 7.6 13.0 8.3 4.2 11.5 15.7 8.6 7.2 6.6 15.4 6.2 5.9 21.0 4.9 8.9 7.1 5.2 13.4 8.5 5.2 9.4 20.6 6.9 10.2 9.0 7.3 6.2 11.3 1.6 8.1 34.6 8.3 3.8 2.7 45.2 1.9 2.2 4.7 3.8 21.1 13.2 0.0 4.7 4.7 3.5 2.2 3.8 5.2 2.8 5.7 4.3 14.7 12.8 25.4 8.8 2.9 7.6 8.2 2.6 6.0 2.2 9.1 19.5 34.0 18.0 2.9 3.5 20.6 33.7 36.5 59.6 14.3 4.2 59.5 32.5 3.8 2.9 3.4 18.6 71.5 2.7 19.6 6.2 29.5 2.1 16.2 6.8 5.4 4.7 1.0 2.5 5.6 5.1 19.6 2.2 8.4 5.5 2.8 1.0 2.1 2.7 1.7 4.0 1.3 1.7 2.4 1.3 1.6 4.6 3.9 2.5 5.5 2.7 2.3 1.9 1.2 8.9 12.6 9.3 10.7 8.8 7.9 9.0 7.6 8.6 5.2 9.4 11.3 18.5 6.4 13.1 28.1 11.0 5.2 10.2 6.6 5.7 73.3 12.1 9.8 15.8 5.7 9.9 20.2 127.2 40.6 15.3 6.3 5.9 16.9 1.6 13.3 19.1 20.5 13.1 15.8 49.4 9.8 10.7 16.4 9.7 10.7 37.4 37.3 11.0 6.4 23.2 95.9 43.2 11.4 2.0 14.2 3.9 1.9 19.3 13.7 7.2 38.4 7.4 20.6 13.4 36.7 63.4 9.3 9.4 15.4 9.8 12.4 6.2 6.6 7.3 143.5 19.7 15.1 14.3 2.8 14.6 8.1 2.6 32.2 19.6 26.1 12.1 10.2 DOCK2 KIAA0209 ENSG00000134516 "Dedicator of cytokinesis 2" Q92608 5 169637268-170083382 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 61.6;lung: 16.4;lymphoid tissue: 51.4" "Cell type enhanced" "Detected in many" "B-cells: 53.3;dendritic cells: 78.1;Kupffer cells: 93.2;Macrophages: 78.0;Microglial cells: 173.3;monocytes: 72.5;T-cells: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 123.4;HDLM-2: 172.7;HL-60: 132.7;HMC-1: 135.8;MOLT-4: 94.5;U-698: 112.4;U-937: 85.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036469 Enhanced NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA036469: AB_2675140" "unprognostic (3.45e-2)" "unprognostic (1.84e-2)" "unprognostic (3.90e-3)" "unprognostic (2.04e-2)" "unprognostic (1.03e-1)" "unprognostic (5.92e-3)" "unprognostic (3.47e-1)" "unprognostic (1.61e-2)" "unprognostic (1.34e-1)" "unprognostic (2.10e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-1)" "unprognostic (2.03e-3)" "unprognostic (1.47e-1)" "unprognostic (2.22e-2)" "unprognostic (6.95e-2)" "unprognostic (7.24e-2)" 7.7 3.6 1.4 34.4 2.4 61.6 3.6 1.9 2.6 3.1 2.8 7.6 5.0 2.3 1.3 3.3 2.4 9.6 1.6 1.8 2.5 1.2 5.5 16.4 42.5 6.4 3.7 1.6 1.9 1.5 0.8 7.3 4.6 1.8 7.8 0.2 2.6 1.9 0.9 1.2 9.6 7.0 4.6 36.5 8.1 1.7 6.3 51.4 1.5 1.4 46.9 9.9 1.1 8.4 0.4 0.3 0.0 0.0 0.0 0.4 0.0 3.3 0.0 8.2 14.3 0.0 0.0 123.4 4.5 13.0 3.9 0.1 0.1 0.6 19.5 172.7 0.3 71.0 3.4 0.0 0.2 132.7 135.8 0.4 0.0 6.3 0.0 5.5 0.5 65.1 1.4 60.3 8.7 0.0 94.5 27.0 0.2 0.0 0.0 59.9 4.8 49.3 3.0 0.0 0.4 0.0 0.5 0.1 0.0 0.0 0.1 64.8 0.4 5.9 6.8 4.1 9.1 18.6 40.9 112.4 7.3 85.1 0.2 19.7 28.6 22.0 12.3 48.6 12.6 13.2 11.3 12.6 29.8 9.7 7.8 9.5 29.4 13.5 72.1 10.9 11.7 24.0 1.4 2.4 1.9 2.6 1.8 2.5 6.4 3.7 4.6 4.6 6.3 8.4 1.4 0.0 3.9 2.0 53.3 0.9 0.2 0.0 0.0 0.0 0.7 2.3 1.7 0.0 2.5 0.0 0.0 0.3 78.1 0.2 0.0 0.0 5.9 0.3 0.3 1.5 0.0 15.1 9.6 0.0 0.3 1.3 1.5 0.3 33.6 0.8 1.8 1.3 42.6 0.0 4.9 0.0 0.0 93.2 31.1 5.6 0.3 78.0 5.4 173.3 72.5 0.0 47.4 4.0 21.7 0.2 0.1 0.0 39.6 0.1 0.0 0.2 0.7 0.1 6.6 0.7 0.6 2.8 1.4 0.2 2.0 0.8 50.8 0.3 0.1 0.1 DROSHA "Etohi2, HSA242976, RN3, RNASE3L, RNASEN" ENSG00000113360 "Drosha ribonuclease III" Q9NRR4 5 31400494-31532196 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ribosome biogenesis, RNA-mediated gene silencing" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031150 Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "HPA031150: AB_2673761" "unprognostic (8.37e-3)" "unprognostic (1.81e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (6.79e-4)" "unprognostic (5.40e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (3.11e-1)" "unprognostic (4.08e-2)" "unprognostic (9.08e-2)" "unprognostic (1.86e-1)" "unprognostic (5.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (6.94e-2)" "unprognostic (2.32e-2)" 12.3 11.3 2.6 15.9 3.8 11.6 11.5 9.4 8.0 13.3 4.2 13.8 13.6 15.9 20.4 11.4 14.5 11.7 13.0 2.0 8.1 12.3 9.7 10.9 16.0 1.1 2.9 20.5 14.4 15.2 4.5 13.8 2.3 13.6 15.6 27.2 12.5 13.2 22.2 13.5 12.2 13.8 0.2 12.5 13.2 11.1 5.2 24.5 15.5 19.6 17.1 12.2 3.9 4.9 38.7 47.3 51.8 70.8 27.0 32.8 74.2 50.0 24.4 45.6 33.9 50.6 49.0 43.3 55.9 36.9 52.7 33.0 63.5 37.8 50.4 40.9 44.6 52.9 157.8 37.0 24.3 59.2 151.6 25.8 26.0 50.7 24.2 34.6 39.5 45.3 68.9 19.7 40.5 38.5 58.3 44.8 49.1 31.2 37.9 52.2 98.9 31.1 25.7 43.2 26.9 35.6 127.1 51.4 30.0 46.0 47.4 34.1 33.9 43.7 50.3 39.0 48.0 35.8 63.5 47.1 30.3 65.9 42.9 0.9 1.2 1.5 2.2 1.3 2.4 1.8 2.4 2.7 2.5 2.0 2.7 2.0 0.3 2.5 2.5 3.0 2.5 1.6 2.6 3.8 9.4 8.0 2.0 8.1 1.1 2.9 2.3 0.2 5.2 4.9 6.2 12.8 14.3 45.4 7.1 3.6 5.0 7.0 10.8 19.4 7.1 6.0 23.4 5.7 12.8 5.5 0.0 8.5 11.4 12.9 3.9 7.8 3.5 12.3 11.6 9.0 11.4 8.0 43.4 8.1 7.6 12.7 8.6 13.6 9.5 20.4 10.0 7.2 7.8 6.7 45.8 8.5 14.2 6.3 3.0 8.2 10.8 6.0 1.8 34.7 8.4 10.2 9.2 74.9 43.9 9.3 10.2 13.2 8.8 6.1 7.3 5.1 16.8 18.8 6.6 10.4 11.6 7.1 10.9 8.8 3.4 4.9 8.3 13.9 11.7 5.9 DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2368.6;Basal prostatic cells: 1651.4;Basal squamous epithelial cells: 3008.4;Cone photoreceptor cells: 1401.1;Oligodendrocytes: 1410.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 488.1;hTERT-HME1: 371.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Microtubules" Cytosol "HPA030200: AB_10601901" "unprognostic (4.87e-3)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (3.60e-2)" "unprognostic (5.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (7.62e-2)" 60.9 86.2 206.5 16.2 275.8 3.3 117.3 240.6 221.9 158.8 143.3 173.2 25.4 167.1 38.2 66.1 103.9 32.6 166.0 194.6 230.7 52.2 80.8 108.0 11.3 258.1 250.4 78.2 39.8 36.7 78.8 28.7 263.4 84.5 32.4 87.4 100.3 48.7 143.1 166.2 64.2 106.0 209.1 36.7 68.9 28.4 243.3 31.4 29.8 104.1 15.2 90.4 113.2 325.4 62.4 26.6 41.2 20.8 79.5 103.5 24.6 82.2 89.7 37.8 42.1 17.1 15.5 10.4 32.2 220.7 35.6 46.7 34.4 161.2 73.0 52.3 45.2 17.8 49.5 31.4 65.9 15.0 0.4 58.3 488.1 92.5 371.6 69.1 73.3 9.5 12.6 38.2 113.9 20.2 5.1 6.8 27.7 35.6 21.9 0.1 28.8 16.5 118.8 83.0 47.2 37.8 32.7 11.7 64.1 67.7 18.6 27.2 176.5 77.3 55.9 37.0 68.9 39.6 28.6 5.0 55.8 8.8 40.3 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 0.3 1.3 0.0 0.1 206.5 275.8 240.6 221.9 194.6 230.7 258.1 250.4 263.4 209.1 243.3 325.4 193.2 336.5 11.8 1048.7 5.6 2368.6 1651.4 250.1 3008.4 673.1 81.0 301.5 862.8 77.2 161.7 55.2 1401.1 61.5 7.8 357.8 7.9 204.3 53.6 133.8 218.4 122.7 44.9 12.4 550.4 66.3 11.6 212.5 71.9 166.8 17.1 478.7 60.7 80.3 21.8 307.9 591.7 100.3 118.0 74.2 124.6 15.5 133.3 56.6 215.3 215.5 46.6 200.8 2.1 630.3 1410.3 194.1 283.0 152.4 27.2 229.8 124.2 10.3 52.0 122.6 65.7 381.8 196.6 20.0 13.7 298.2 857.2 26.5 19.7 30.5 48.1 142.8 DUSP1 "CL100, HVH1, MKP-1, PTPN10" ENSG00000120129 "Dual specificity phosphatase 1" P28562 5 172768096-172771195 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 2357.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 7426.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 7426.8" "Cell line enhanced" "Detected in all" "HHSteC: 201.0;hTCEpi: 359.3;REH: 202.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069577 Approved Nucleoli,Cytosol NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Nucleoli Cytosol "HPA069577: AB_2686156" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (9.73e-2)" "unprognostic (8.17e-2)" "unprognostic (4.64e-1)" "unprognostic (1.58e-3)" "unprognostic (4.18e-2)" "unprognostic (6.94e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (3.11e-5)" "unprognostic (2.69e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-3)" 922.6 515.4 84.9 364.9 85.8 692.4 586.1 134.8 121.1 501.3 134.7 336.1 66.0 382.3 42.0 526.6 677.4 570.5 395.3 79.4 114.6 281.2 721.3 719.9 178.6 132.0 90.3 541.2 240.1 116.5 319.5 297.3 104.1 438.5 228.5 202.7 350.3 356.9 251.8 1054.1 170.3 452.7 123.7 304.7 396.0 68.1 115.4 131.3 612.9 451.3 56.2 778.1 610.0 121.2 10.7 26.5 8.2 11.5 175.6 102.2 14.0 170.3 49.3 111.9 45.0 29.2 12.4 3.5 48.6 120.4 128.1 4.7 8.1 42.3 52.1 95.8 22.4 2.3 63.1 12.6 201.0 1.2 3.8 98.1 359.3 50.9 82.1 58.2 35.6 7.4 9.0 66.1 73.1 12.6 5.7 5.0 7.4 8.2 7.7 202.2 15.3 32.3 80.2 5.4 35.5 14.9 46.2 76.9 6.3 34.1 6.7 1.9 94.1 79.1 39.8 77.8 13.4 13.6 8.4 3.1 70.3 1.8 3.3 931.4 584.5 1640.7 85.0 589.2 212.6 57.6 75.6 88.6 263.4 54.1 35.9 40.7 7426.8 114.5 791.6 14.3 68.1 409.9 84.9 85.8 134.8 121.1 79.4 114.6 132.0 90.3 104.1 123.7 115.4 121.2 1856.5 410.3 341.0 23.8 918.4 1279.8 1140.5 456.9 1810.4 73.0 464.2 567.7 211.3 739.2 243.1 211.5 27.1 316.2 618.9 633.7 56.7 335.9 71.6 531.6 990.9 870.4 715.5 193.5 11.9 88.7 407.2 1367.4 597.3 1013.7 301.1 175.8 781.4 345.7 1043.0 48.8 13.4 891.8 207.5 1525.5 2357.3 40.3 384.9 1965.5 542.5 66.5 173.3 1159.3 33.0 6.6 4.1 226.3 683.3 311.1 952.2 685.7 736.1 35.5 218.0 190.5 769.2 720.7 671.9 12.9 24.6 1996.9 1956.6 582.0 1015.2 223.4 415.8 676.6 DUSP14 "MKP-L, MKP6" ENSG00000276023 "Dual specificity phosphatase 14" O95147 17 37489891-37513501 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 44.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 179.7;Basal prostatic cells: 239.3;Cytotrophoblasts: 162.8;Endometrial ciliated cells: 146.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HBF TERT88: 36.4;SuSa: 24.9;WM-115: 37.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019911 Approved Approved Nucleoplasm,Cytosol NA Yes 79000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "HPA019911: AB_1847888" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.60e-1)" "unprognostic (3.22e-2)" "unprognostic (3.43e-3)" "unprognostic (2.02e-3)" "unprognostic (2.18e-1)" "unprognostic (2.59e-1)" "unprognostic (7.02e-3)" "unprognostic (3.81e-1)" "prognostic unfavorable (6.97e-9)" "unprognostic (7.93e-2)" "unprognostic (1.97e-1)" "unprognostic (1.73e-1)" "unprognostic (1.41e-3)" 15.3 14.2 10.9 1.3 11.2 0.3 12.4 11.2 17.0 12.8 10.9 10.3 0.0 9.5 5.5 17.4 7.5 1.2 14.1 11.0 10.9 8.7 15.2 8.6 0.4 11.9 11.1 5.6 6.6 1.0 14.5 0.9 10.6 6.4 1.0 9.9 13.1 0.3 11.0 44.1 5.5 0.8 10.4 2.8 7.6 13.7 10.8 4.4 23.1 4.4 2.7 7.2 17.1 10.7 2.6 0.2 4.9 2.1 0.1 0.6 2.1 10.4 7.8 14.3 15.6 1.2 17.9 0.2 0.9 7.6 0.2 2.8 0.2 6.1 36.4 0.2 0.7 0.0 1.6 6.2 1.5 0.5 3.0 8.5 5.5 4.8 2.5 10.2 0.3 0.2 0.6 3.1 11.4 0.4 9.7 1.7 0.3 3.8 0.0 2.5 0.6 2.5 17.5 2.4 1.9 0.3 0.5 17.6 4.1 24.9 0.8 3.9 1.4 10.8 5.8 0.1 5.8 0.1 0.3 0.1 0.1 0.0 37.5 1.1 0.0 0.7 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.7 1.6 0.0 0.2 0.0 0.0 0.2 10.9 11.2 11.2 17.0 11.0 10.9 11.9 11.1 10.6 10.4 10.8 10.7 15.0 6.4 5.4 2.9 8.3 179.7 239.3 74.8 129.1 6.8 42.6 46.0 15.0 4.3 39.6 7.3 8.4 162.8 16.6 0.3 29.4 34.8 36.4 146.9 18.5 21.7 2.4 11.4 12.0 15.1 82.1 30.2 3.1 85.3 87.0 10.6 14.6 15.7 19.7 15.2 5.3 1.2 36.7 2.8 34.8 52.5 13.7 5.9 62.2 4.7 25.3 16.1 15.5 3.0 3.3 74.8 2.9 6.0 9.9 64.9 0.1 16.9 61.3 24.5 0.0 13.2 45.2 26.0 33.4 44.0 92.6 67.9 18.2 26.3 1.1 67.0 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350684 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 32.2;stomach 1: 32.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 155.5;Ionocytes: 126.1;Pancreatic endocrine cells: 195.2" "Cancer enhanced" "Detected in all" "melanoma: 42.9" "Region enhanced" "Detected in many" "hippocampal formation: 20.9" "Immune cell enriched" "Detected in single" 9 "T-reg: 6.7" "Lineage enriched" "Detected in single" 20 "T-cells: 6.7" "Cell line enhanced" "Detected in many" "A549: 100.0;OE19: 91.7;SK-MEL-30: 157.2;WM-115: 122.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA061967: AB_2684648" "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 15.2 5.2 2.3 5.4 1.4 6.2 23.7 5.0 9.0 6.0 0.4 1.2 1.2 4.5 0.1 2.5 1.9 11.3 2.3 20.9 1.2 2.8 0.7 5.7 2.6 1.6 1.1 0.4 32.2 0.6 5.3 7.5 1.1 5.2 1.4 5.9 16.1 10.1 4.2 5.6 2.0 1.2 0.3 1.0 32.4 2.8 2.9 4.2 1.2 0.9 2.7 13.8 2.8 1.1 38.0 100.0 57.9 2.8 7.2 0.0 4.9 7.7 42.0 22.8 10.1 1.1 18.8 0.0 20.5 3.6 16.0 12.0 0.7 25.7 13.5 1.0 1.9 0.3 3.7 0.7 0.2 0.5 47.3 4.6 16.7 7.1 42.1 49.7 18.9 0.4 0.3 4.5 46.0 42.9 0.1 7.1 10.1 91.7 60.5 1.2 1.9 8.1 52.3 19.7 0.4 32.0 10.8 49.5 157.2 1.1 10.7 1.1 53.3 16.7 0.3 0.0 5.7 11.6 1.4 0.1 50.2 8.9 122.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 6.7 0.0 2.3 1.4 5.0 9.0 20.9 1.2 1.6 1.1 1.1 0.3 2.9 1.1 11.1 0.0 2.8 0.0 33.5 12.1 98.3 27.3 4.0 43.2 80.4 62.2 2.6 51.5 51.1 0.0 12.5 3.2 24.0 1.9 0.0 74.3 7.6 64.7 13.3 16.3 97.8 0.0 3.8 78.6 40.9 9.6 121.8 155.5 6.3 0.0 21.8 0.3 25.0 43.7 8.2 8.5 126.1 4.0 102.8 25.6 0.3 47.4 65.8 0.0 75.6 0.8 0.0 1.5 0.3 195.2 0.0 0.0 31.0 30.9 0.4 0.2 43.6 3.4 13.1 18.9 17.8 1.4 8.2 2.3 11.9 17.8 115.6 0.1 4.6 102.7 DVL3 KIAA0208 ENSG00000161202 "Dishevelled segment polarity protein 3" Q92997 3 184155377-184173614 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046486, HPA058265" Approved Approved "Intermediate filaments,Midbody ring,Centrosome" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Midbody ring, Centrosome" "Intermediate filaments" "CAB046486: AB_10610845, HPA058265: AB_2683658" "unprognostic (2.20e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.88e-2)" "unprognostic (1.64e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (8.61e-2)" "unprognostic (5.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (4.77e-5)" "prognostic unfavorable (1.53e-8)" "unprognostic (1.87e-1)" "unprognostic (4.10e-1)" "unprognostic (8.41e-2)" "unprognostic (3.95e-1)" 35.2 28.1 16.4 18.7 17.4 18.6 29.8 17.4 18.9 39.0 15.9 46.0 17.2 44.7 16.1 30.3 34.5 22.6 35.0 16.4 17.1 25.7 20.0 31.7 13.9 18.1 17.3 42.0 25.6 17.9 24.4 38.3 17.6 29.1 16.1 22.8 25.6 25.8 34.9 33.8 27.1 31.7 16.6 25.6 27.9 15.1 17.0 12.4 30.0 22.3 15.9 36.6 31.6 18.3 47.9 13.6 36.4 41.4 37.5 37.8 95.0 28.4 28.9 32.7 27.6 43.6 18.3 33.6 73.3 37.0 32.4 40.8 29.6 22.2 23.4 54.0 32.2 38.1 21.3 28.2 56.6 21.2 27.8 38.4 39.9 23.4 27.3 55.9 24.6 21.6 38.9 44.2 35.5 46.5 28.3 25.2 32.8 34.6 22.1 49.9 42.7 30.0 31.7 36.2 36.3 51.0 34.9 39.8 67.4 35.8 98.7 26.8 25.0 29.5 28.5 31.0 43.8 48.3 38.8 37.0 30.0 22.4 23.6 0.1 0.6 1.3 0.6 1.0 0.8 0.7 0.4 0.7 0.6 0.5 0.5 0.3 0.9 0.4 0.3 0.8 0.2 0.4 16.4 17.4 17.4 18.9 16.4 17.1 18.1 17.3 17.6 16.6 17.0 18.3 15.9 25.6 14.1 16.6 10.8 18.7 15.7 12.9 15.9 20.1 23.5 16.5 26.9 12.8 17.2 22.0 27.1 34.4 14.6 40.8 23.5 13.3 12.8 23.2 30.9 15.9 34.3 6.9 11.4 16.6 21.6 22.6 32.6 27.7 17.1 29.7 19.2 20.5 20.3 62.2 11.8 22.3 12.2 16.2 14.4 47.5 33.5 17.4 12.4 14.0 10.8 19.7 14.4 9.0 11.5 20.7 18.9 37.2 13.9 20.8 25.2 18.3 13.4 18.5 19.7 23.6 27.1 10.6 12.4 20.4 21.7 52.1 10.3 21.9 21.5 25.7 DYNLL1 "DLC1, DLC8, DNCL1, hdlc1, LC8, PIN" ENSG00000088986 "Dynein light chain LC8-type 1" P63167 12 120469850-120498493 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation, Transport" "Activator, Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 4098.6;Respiratory ciliated cells: 2679.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA Yes 890000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (2.88e-2)" "unprognostic (5.63e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (4.41e-3)" "unprognostic (4.64e-2)" "unprognostic (6.17e-3)" "unprognostic (1.61e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (7.97e-7)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (7.91e-2)" "unprognostic (1.62e-1)" 268.6 261.9 912.5 186.7 967.7 126.8 268.0 895.2 1292.9 354.2 894.7 325.8 162.8 319.4 322.3 719.9 544.2 242.7 257.5 975.4 944.7 352.6 238.4 222.6 241.6 896.1 898.5 247.0 225.1 228.2 309.7 259.2 914.2 225.9 327.4 181.3 245.4 264.6 85.6 626.7 206.3 390.1 935.1 185.2 244.5 360.3 909.7 306.5 176.1 163.9 357.8 389.8 474.4 1001.2 721.6 811.4 779.2 600.8 677.1 713.6 250.8 968.0 451.6 785.6 466.7 770.8 472.3 400.6 510.3 945.1 753.0 629.6 949.3 818.3 781.0 528.3 617.9 390.4 532.9 1062.5 676.2 412.8 620.5 436.2 863.0 584.6 477.5 855.7 831.8 421.5 502.0 446.1 1056.8 960.1 541.4 894.8 642.2 917.7 935.7 543.0 403.0 499.2 1143.1 659.8 535.2 392.0 789.3 677.7 926.6 812.6 673.6 595.3 635.2 592.3 502.1 525.6 852.2 264.0 562.8 404.6 656.8 645.1 776.6 516.6 291.9 384.2 200.6 303.3 155.3 310.4 207.2 211.7 281.8 219.0 132.0 165.7 50.1 282.9 334.8 461.6 373.5 353.0 912.5 967.7 895.2 1292.9 975.4 944.7 896.1 898.5 914.2 935.1 909.7 1001.2 810.1 195.5 101.9 79.3 341.4 922.2 359.1 1275.0 356.8 138.4 800.0 949.4 170.8 303.1 764.6 399.1 83.4 524.6 484.1 689.9 1113.2 691.2 1407.2 1842.5 528.5 541.9 480.8 332.9 111.2 538.9 897.4 538.5 240.5 488.1 316.7 611.9 521.9 499.0 732.1 85.8 62.8 801.6 1121.0 329.4 706.1 4098.6 516.6 466.3 595.9 42.2 701.6 164.0 248.2 47.3 156.4 754.9 798.6 701.8 234.9 304.7 533.4 1125.0 2679.6 193.5 368.1 440.7 1016.3 961.5 721.4 1005.4 1610.1 1006.6 396.6 586.3 498.2 389.6 DYRK2 ENSG00000127334 "Dual specificity tyrosine phosphorylation regulated kinase 2" Q92630 12 67648338-67665406 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 133.1;Horizontal cells: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027230, HPA056902" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA027230: AB_1847925, HPA056902: AB_2683271" "unprognostic (5.86e-3)" "unprognostic (4.18e-1)" "unprognostic (4.08e-3)" "unprognostic (2.56e-3)" "unprognostic (1.18e-2)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (7.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" 9.9 4.6 2.9 14.2 3.3 14.9 6.3 2.3 6.1 7.8 3.2 25.7 20.4 13.1 6.2 10.7 10.0 14.3 24.4 8.6 2.3 4.7 4.2 9.1 21.6 3.4 2.3 8.7 8.6 4.9 3.0 14.1 2.7 6.5 21.9 14.8 5.4 8.8 39.4 7.5 28.0 13.0 3.1 14.7 20.6 5.0 2.7 24.1 6.9 10.4 14.2 11.9 7.6 3.5 24.5 13.4 19.8 14.4 9.7 13.2 15.8 24.2 15.7 11.6 6.6 17.9 13.2 45.3 29.2 35.3 7.1 27.8 16.0 9.6 12.4 19.6 20.9 7.3 9.5 6.9 3.8 16.8 15.2 11.0 13.3 31.4 24.8 19.6 6.6 18.9 9.2 22.9 15.1 13.9 14.4 8.2 17.2 15.8 21.5 37.9 19.7 20.0 13.6 30.2 26.0 30.7 10.1 13.4 13.9 13.3 9.2 13.9 10.0 18.4 17.3 12.8 19.4 10.9 1.9 24.9 17.6 11.1 19.4 2.0 0.3 4.0 3.2 0.7 2.3 1.8 2.3 4.2 1.2 2.0 1.9 3.7 0.4 4.7 0.9 0.5 2.0 1.1 2.9 3.3 2.3 6.1 8.6 2.3 3.4 2.3 2.7 3.1 2.7 3.5 13.0 9.6 10.2 3.9 14.4 11.3 11.9 6.7 8.6 18.0 7.4 8.1 44.5 20.0 11.2 1.8 22.9 3.5 28.6 133.1 0.0 19.0 0.6 28.0 35.9 12.1 24.6 4.8 11.0 18.2 7.9 18.9 25.0 15.6 5.7 13.3 6.4 6.1 17.0 80.8 11.4 62.0 4.1 15.7 22.5 2.0 11.5 15.5 8.8 13.1 12.0 16.7 42.2 6.0 9.1 17.7 61.3 13.2 9.0 16.1 62.9 11.3 30.3 23.3 13.1 53.5 33.6 2.7 10.1 15.6 16.2 4.5 31.0 17.9 32.3 34.4 E2F1 "RBBP3, RBP3" ENSG00000101412 "E2F transcription factor 1" Q01094 20 33675477-33686385 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.0;Granulosa cells: 11.4;Spermatogonia: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000329, HPA008003, CAB019308, HPA029735" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 22: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Centrosome" "CAB000329: AB_627476, CAB019308: , HPA008003: AB_1847936, HPA029735: AB_2673176" "unprognostic (7.46e-2)" "prognostic favorable (9.22e-6)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.33e-5)" "unprognostic (1.51e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.83e-5)" "unprognostic (1.25e-2)" "unprognostic (8.23e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (4.18e-4)" "unprognostic (3.15e-2)" "prognostic unfavorable (8.99e-5)" "unprognostic (1.05e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.62e-4)" "unprognostic (1.91e-1)" 1.8 5.5 7.1 5.6 7.1 34.3 1.6 5.2 9.2 1.8 3.9 3.8 3.2 1.2 0.2 5.7 1.3 0.7 1.4 6.1 5.6 0.9 1.8 3.7 8.7 7.6 6.4 3.5 1.0 1.3 0.6 2.4 6.5 1.9 3.9 0.7 1.9 0.9 1.6 4.7 4.1 2.8 7.0 5.0 3.7 10.4 6.9 10.7 0.8 0.8 6.9 2.4 2.5 8.3 48.1 45.4 52.0 40.5 5.2 3.6 39.3 45.0 21.4 55.9 46.7 81.1 48.0 87.3 44.2 20.2 67.7 35.4 25.3 23.8 24.8 26.4 36.5 71.6 71.9 47.7 0.4 34.0 43.6 2.8 1.4 30.6 5.4 5.7 14.6 54.4 19.3 60.0 34.9 42.3 72.8 71.6 15.6 47.9 64.6 71.4 140.7 36.2 9.6 28.7 76.7 54.1 54.6 37.6 22.7 14.8 47.3 42.4 7.9 65.0 37.7 45.8 64.8 58.1 42.0 72.6 54.1 20.0 39.3 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.1 0.1 0.1 7.1 7.1 5.2 9.2 6.1 5.6 7.6 6.4 6.5 7.0 6.9 8.3 1.1 0.0 1.1 0.7 3.6 2.9 1.7 0.5 0.0 2.3 3.1 4.3 0.4 0.0 1.4 0.0 0.0 5.0 2.9 2.4 0.0 0.9 1.0 0.3 1.0 1.6 0.0 25.0 1.5 0.2 9.6 3.0 7.7 1.2 0.0 11.4 0.7 0.8 4.4 0.0 0.5 4.6 2.0 0.6 2.1 3.1 2.1 3.1 1.8 1.0 0.1 1.5 1.0 1.0 3.4 0.6 0.5 1.2 9.7 0.5 1.4 0.1 0.2 2.3 0.0 1.0 3.0 7.5 32.9 3.7 1.7 1.8 3.3 1.2 7.0 3.5 E2F3 ENSG00000112242 "E2F transcription factor 3" O00716 6 20401879-20493714 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029779, HPA065012" Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA029779: AB_2732448, HPA065012: AB_2685403" "unprognostic (4.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-3)" "unprognostic (2.96e-1)" "unprognostic (9.14e-2)" "unprognostic (8.99e-3)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.69e-4)" "unprognostic (1.14e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (1.63e-8)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (3.50e-1)" "unprognostic (5.99e-3)" 6.5 4.9 4.8 9.8 5.2 19.8 4.1 2.8 5.7 3.3 3.0 5.4 5.2 3.6 3.9 4.9 2.5 6.4 5.1 6.4 4.6 5.8 4.4 4.9 11.0 3.7 4.6 1.4 2.1 3.1 1.8 5.6 4.2 3.3 6.3 6.1 2.7 3.1 10.0 2.6 5.7 6.0 3.7 8.4 3.6 3.4 5.5 8.6 8.5 9.3 9.5 8.5 2.7 3.8 14.3 11.6 32.2 35.1 10.9 11.9 22.0 18.9 16.8 18.2 19.9 14.3 8.8 32.3 35.2 18.2 16.9 14.6 37.8 17.4 30.3 12.2 25.3 58.1 20.4 16.3 11.6 38.6 33.0 9.7 12.6 17.7 21.6 18.8 12.7 29.8 65.3 19.4 20.9 15.0 43.6 43.2 24.2 11.0 11.9 46.5 27.8 36.5 21.8 25.1 22.9 42.2 17.3 24.1 26.3 20.0 12.4 23.4 17.2 28.6 17.4 14.2 30.5 12.1 40.1 38.3 7.1 23.2 41.3 5.6 2.3 1.1 1.6 1.6 2.0 0.4 1.0 2.4 2.6 0.4 0.8 1.8 7.2 3.5 1.1 1.1 1.6 1.1 4.8 5.2 2.8 5.7 6.4 4.6 3.7 4.6 4.2 3.7 5.5 3.8 4.8 0.0 2.6 53.8 10.6 9.2 12.3 7.0 7.4 34.1 11.9 7.2 10.6 4.3 10.6 7.3 22.9 8.3 15.0 12.0 9.8 7.6 12.2 3.9 14.1 8.5 12.0 17.2 67.7 6.9 13.8 9.2 12.8 10.6 20.3 32.3 14.6 4.7 17.1 32.0 31.9 11.7 4.1 47.2 17.7 5.7 2.8 28.7 5.4 27.2 23.8 2.9 15.5 37.7 2.9 14.8 10.3 3.0 19.1 22.1 4.5 25.1 2.2 9.0 0.0 9.0 11.5 3.0 4.7 16.5 8.9 3.1 15.3 5.7 13.8 18.4 E2F5 ENSG00000133740 "E2F transcription factor 5" Q15329 8 85177154-85217158 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.6" "Cell type enhanced" "Detected in many" "B-cells: 23.7;Plasma cells: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 13.4;naive B-cell: 8.9" "Lineage enriched" "Detected in many" 9 "B-cells: 13.4" "Cell line enhanced" "Detected in many" "AF22: 82.6;Daudi: 158.0;U-698: 77.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055723, HPA065441" Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli, Vesicles" "HPA055723: AB_2682897, HPA065441: " "unprognostic (8.73e-2)" "unprognostic (3.45e-1)" "unprognostic (3.15e-2)" "unprognostic (1.02e-3)" "unprognostic (6.73e-3)" "unprognostic (1.62e-1)" "unprognostic (3.36e-5)" "unprognostic (1.23e-1)" "unprognostic (9.53e-2)" "unprognostic (1.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (1.89e-6)" "unprognostic (2.88e-2)" "unprognostic (3.25e-2)" "unprognostic (3.64e-1)" "unprognostic (2.95e-3)" 1.8 3.9 4.8 8.0 5.2 1.7 6.7 4.6 6.5 5.2 5.1 6.6 4.9 4.5 8.1 2.2 8.0 4.3 1.9 5.1 5.8 8.1 3.0 4.1 25.9 5.5 5.2 4.9 4.3 13.2 3.7 5.0 5.0 3.6 7.8 0.9 2.3 3.3 0.4 0.8 3.8 4.1 5.1 6.9 5.5 8.5 5.3 10.7 8.7 0.9 29.6 6.9 0.9 5.5 14.2 15.9 82.6 29.7 1.5 2.2 25.0 2.7 6.9 2.4 7.4 9.6 17.4 158.0 10.3 3.5 28.4 2.6 51.0 4.3 3.0 16.0 20.1 16.4 8.3 22.4 13.4 4.8 0.1 3.3 6.9 3.5 12.0 15.7 2.7 16.5 34.7 1.2 4.6 10.0 15.8 10.8 26.1 28.0 12.9 12.9 3.4 17.9 27.5 10.7 9.8 29.8 1.8 5.8 23.8 32.6 33.5 5.2 0.1 3.7 2.5 4.6 10.5 27.6 20.6 77.1 4.3 4.1 8.0 0.0 0.0 0.0 0.1 0.0 0.0 13.4 0.0 0.0 0.1 8.9 0.2 0.4 0.0 1.4 0.0 1.5 0.6 0.6 4.8 5.2 4.6 6.5 5.1 5.8 5.5 5.2 5.0 5.1 5.3 5.5 1.1 0.0 6.5 3.6 23.7 2.3 3.3 1.3 1.2 0.9 5.6 6.0 1.0 5.7 2.9 5.5 10.4 4.1 5.1 3.3 0.0 3.3 7.6 7.3 5.2 1.5 7.8 1.3 7.7 2.6 1.1 3.0 4.1 7.5 1.3 5.5 0.4 2.4 0.5 0.0 4.6 2.7 2.0 0.8 1.0 3.8 1.5 1.9 3.6 4.7 0.3 5.2 4.1 11.6 4.2 3.0 1.7 1.9 29.6 6.9 0.8 5.8 8.6 1.6 0.0 5.0 4.5 8.1 4.6 2.3 2.8 1.1 2.5 4.6 3.7 2.1 EBAG9 "EB9, RCAS1" ENSG00000147654 "Estrogen receptor binding site associated antigen 9" O00559 8 109539711-109565996 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021153, HPA021154, CAB072810, CAB072811, CAB072812" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "CAB072810: , CAB072811: , CAB072812: , HPA021153: AB_1856151, HPA021154: AB_1856152" "unprognostic (3.04e-2)" "unprognostic (9.99e-2)" "unprognostic (2.08e-1)" "unprognostic (1.99e-1)" "unprognostic (5.06e-2)" "unprognostic (8.13e-2)" "unprognostic (2.63e-1)" "unprognostic (3.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (3.72e-1)" "unprognostic (9.72e-3)" "unprognostic (6.46e-2)" "unprognostic (5.16e-1)" "unprognostic (3.53e-1)" "unprognostic (3.71e-2)" 23.3 28.4 18.6 17.6 19.9 16.9 32.4 23.4 26.3 36.1 19.8 28.6 23.5 22.8 44.7 17.0 27.6 19.4 24.7 19.1 20.5 37.0 45.2 28.1 25.4 18.9 19.0 22.2 36.7 34.9 20.5 18.1 19.0 23.3 31.2 32.5 42.9 27.6 53.2 17.9 21.0 17.0 19.1 20.7 27.2 25.3 19.3 20.6 57.4 42.3 27.0 17.2 15.3 20.2 36.7 25.2 25.3 17.3 15.3 24.9 19.7 19.5 14.6 27.0 25.4 25.7 38.1 51.7 33.0 13.8 21.8 25.2 24.4 31.3 28.5 57.6 26.9 56.9 15.8 39.6 34.3 20.0 16.1 19.9 60.1 23.4 47.2 21.9 25.7 45.8 59.8 37.0 24.0 55.8 58.2 31.5 15.8 70.1 25.2 30.9 20.1 43.7 31.4 23.7 27.6 22.1 21.3 22.6 27.6 18.4 44.7 25.6 17.5 20.9 15.0 19.1 14.4 54.9 38.3 48.7 21.2 52.7 19.6 5.8 13.4 14.7 19.3 19.5 34.1 40.7 27.1 27.0 22.5 40.3 33.5 30.4 2.8 29.4 17.3 23.8 33.4 14.7 18.6 19.9 23.4 26.3 19.1 20.5 18.9 19.0 19.0 19.1 19.3 20.2 32.0 121.8 102.4 12.7 40.2 21.7 28.6 51.8 44.9 34.5 36.8 46.0 37.6 54.3 65.1 29.5 6.2 50.2 24.0 33.6 64.6 47.3 134.7 42.9 26.7 34.5 31.8 36.0 16.1 65.8 34.0 28.8 22.4 33.0 46.9 16.0 23.2 48.8 32.7 50.5 16.1 39.4 50.8 24.7 22.1 115.0 29.2 27.9 19.6 11.2 25.3 53.4 27.8 18.1 16.1 38.5 41.3 23.0 53.8 36.8 50.5 58.5 61.8 34.7 32.9 35.1 32.1 101.6 50.4 40.5 19.9 22.2 28.5 34.7 46.0 31.7 EBF1 "COE1, EBF, OLF1" ENSG00000164330 "EBF transcription factor 1" Q9UH73 5 158695916-159099916 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.7" "Cell type enhanced" "Detected in many" "Adipocytes: 79.8;Fibroblasts: 108.4;Leydig cells: 285.5;Microglial cells: 255.8;Peritubular cells: 121.5;Sertoli cells: 98.6;Smooth muscle cells: 138.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 12.1;naive B-cell: 10.2" "Lineage enriched" "Detected in single" 24 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "ASC diff: 30.0;HSkMC: 26.7;REH: 82.6;U-2197: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (7.86e-2)" "unprognostic (3.08e-2)" "unprognostic (7.29e-2)" "unprognostic (4.70e-2)" "unprognostic (2.63e-1)" "unprognostic (1.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" "unprognostic (5.75e-2)" "unprognostic (1.60e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (9.62e-7)" "prognostic unfavorable (7.80e-4)" "unprognostic (5.75e-2)" "unprognostic (5.81e-2)" "unprognostic (4.37e-3)" 37.7 2.8 4.6 3.8 5.0 3.3 20.5 16.4 5.0 14.6 3.9 5.1 1.1 10.5 4.1 3.5 12.5 8.1 7.9 3.8 5.0 3.3 0.4 4.3 9.4 9.8 7.5 8.5 1.7 1.6 2.4 10.8 7.1 4.8 3.2 2.0 4.7 4.4 4.7 7.6 5.5 7.7 11.6 4.7 3.5 4.0 5.3 2.5 7.5 7.4 9.2 10.4 10.3 4.9 0.0 0.5 12.8 0.0 30.0 11.9 0.2 0.3 0.0 0.7 1.7 0.0 0.0 11.9 0.0 4.0 2.4 0.1 0.5 0.1 0.2 2.8 0.2 0.0 3.5 0.0 1.0 0.1 0.3 26.7 0.0 11.4 0.4 0.0 0.0 0.3 0.0 0.2 0.9 0.0 0.1 0.2 1.2 0.0 0.0 82.6 0.6 0.2 0.0 0.0 6.8 1.7 0.7 0.3 0.0 0.2 0.0 0.1 0.0 15.3 1.8 17.5 0.3 0.0 0.1 11.1 10.2 1.2 13.0 0.5 0.0 0.1 0.0 0.0 0.0 12.1 0.0 0.0 0.0 10.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 4.6 5.0 16.4 5.0 3.8 5.0 9.8 7.5 7.1 11.6 5.3 4.9 79.8 0.0 0.5 5.2 76.3 12.2 0.3 0.0 1.8 5.9 0.8 1.9 5.0 0.0 0.7 1.8 0.0 0.2 0.2 0.1 0.0 3.9 28.2 1.5 54.2 56.3 0.0 0.4 0.4 0.0 0.3 108.4 1.5 1.4 0.0 0.0 4.6 2.2 0.8 0.0 1.6 0.1 0.0 0.3 16.6 21.7 285.5 1.9 14.2 255.8 9.3 1.9 0.0 3.0 0.9 0.1 0.0 121.5 7.7 0.7 0.0 0.1 0.9 2.3 98.6 4.6 138.8 2.7 1.3 1.6 7.0 0.4 5.0 10.7 0.0 1.7 EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 44.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 749.7;Ductal cells: 316.3;Glandular and luminal cells: 289.7;Pancreatic endocrine cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cell line enhanced" "Detected in many" "EFO-21: 660.4;HUVEC TERT2: 446.8;T-47d: 137.5;TIME: 334.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" NA Yes 9740 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" 44.6 1.8 14.7 7.3 13.8 4.7 23.6 13.6 18.2 6.2 9.7 10.6 10.4 7.0 6.3 12.1 9.4 13.5 7.8 12.6 12.2 7.7 3.1 36.6 5.6 15.1 13.6 2.6 9.6 1.4 1.1 18.5 15.2 5.5 14.5 1.0 12.1 8.9 7.6 11.8 9.8 11.3 13.1 12.3 10.4 4.7 15.7 1.7 3.4 6.4 2.4 9.9 5.9 14.2 10.3 57.6 1.1 0.1 0.3 0.2 0.2 18.2 16.0 15.0 12.4 74.6 8.6 0.0 660.4 7.2 9.2 5.4 0.0 10.6 11.0 0.8 0.0 0.0 2.1 2.3 0.8 0.0 0.0 0.4 6.2 3.0 2.1 4.7 446.8 0.0 0.0 0.0 56.8 1.6 0.2 0.3 0.6 10.4 0.7 0.2 5.1 0.1 35.3 9.4 0.6 0.0 1.8 53.1 0.1 117.2 137.5 0.8 334.3 37.1 30.1 0.7 23.5 0.3 0.4 1.3 0.3 0.0 1.6 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.0 0.0 14.7 13.8 13.6 18.2 12.6 12.2 15.1 13.6 15.2 13.1 15.7 14.2 190.7 173.1 23.8 2.9 0.8 189.9 749.7 99.9 151.4 0.2 68.7 26.8 2.2 8.6 110.6 38.6 0.0 1.8 0.8 189.7 3.9 316.3 13.3 187.2 16.3 236.8 15.6 2.7 3.6 218.9 0.4 9.0 22.4 289.7 1.3 0.8 169.2 1.8 1.8 1.7 3.0 43.8 12.2 5.0 6.7 19.8 5.6 5.3 8.8 6.5 10.9 0.3 0.0 3.5 0.6 268.5 145.7 0.4 0.4 185.8 119.6 8.3 27.4 0.4 6.6 1.8 21.8 1.0 0.6 53.7 64.5 0.8 9.7 0.1 196.6 141.8 EEF1A1 "EE1A1, EEF1A, EF1A, LENG7" ENSG00000156508 "Eukaryotic translation elongation factor 1 alpha 1" P68104 6 73489308-73525587 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "Elongation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051759, HPA053862, HPA056990" Supported Supported Cytosol NA NA 82000000 "Cluster 30: Non-specific - Translation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA051759: AB_2681595, HPA053862: AB_2797248, HPA056990: AB_2683302" "unprognostic (6.47e-2)" "unprognostic (7.86e-3)" "unprognostic (2.53e-2)" "unprognostic (9.64e-2)" "unprognostic (1.39e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (3.13e-1)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (1.41e-1)" "unprognostic (3.47e-1)" "unprognostic (8.61e-2)" "unprognostic (1.65e-1)" "unprognostic (8.00e-2)" "unprognostic (2.04e-1)" "unprognostic (7.73e-2)" 7265.1 5743.3 2531.3 4576.8 2717.1 10489.1 10504.6 2524.2 2783.1 7953.2 2902.2 6991.5 4783.5 7397.5 7203.8 6302.2 9034.9 4902.1 4074.6 2309.3 2687.4 7520.3 6459.1 4891.3 8813.5 2792.2 2572.6 12627.2 10370.0 6942.9 3776.4 5545.3 2828.4 5639.5 6936.4 2200.9 8381.0 6045.9 1682.1 7151.8 5076.6 7695.8 2980.6 5912.7 5776.4 1701.2 2687.7 8091.2 8348.4 1938.8 11294.9 6993.4 6470.3 2900.2 5218.1 8235.8 8697.0 13940.8 18183.0 32963.3 7874.7 7061.7 21384.2 10632.9 10044.2 12591.7 8020.5 20786.6 9976.7 13824.2 6089.1 5849.1 11729.0 15249.9 9969.0 3868.8 7099.6 7824.7 6142.2 13619.5 14708.8 15773.6 9201.9 26454.1 27514.4 7357.6 24803.6 17437.1 14783.4 8434.8 15242.2 7357.1 13131.5 8385.7 7184.5 17411.3 10348.2 6259.3 4400.0 14212.5 15389.7 26105.5 12201.5 14719.8 8337.9 8853.1 3931.6 10026.7 17535.8 9067.6 6928.7 24671.0 11535.0 4637.5 6195.9 3343.0 9206.4 7296.2 6913.1 5011.8 4780.9 12625.1 7404.1 2888.1 8472.3 895.8 7474.9 7600.7 14243.9 10580.7 12006.0 10174.3 8618.3 8426.8 13912.6 12049.7 681.7 9555.0 7680.9 6461.2 9278.5 26796.5 2531.3 2717.1 2524.2 2783.1 2309.3 2687.4 2792.2 2572.6 2828.4 2980.6 2687.7 2900.2 4915.6 3169.9 6059.2 107.4 11291.6 9829.9 12187.6 10417.5 11667.5 978.9 10528.4 9476.3 160.6 6258.2 5739.8 2637.3 546.3 9401.2 8653.6 2189.4 10344.0 5796.3 1373.9 4535.2 6754.2 5952.7 3862.8 6396.8 84.5 10404.1 12700.2 5756.1 4472.5 5831.2 3736.3 5732.4 6124.7 3323.0 6415.2 494.6 109.3 6969.3 3289.7 7779.7 8970.1 2325.8 8931.5 6705.0 5112.0 175.2 18016.6 3733.0 8468.7 76.9 162.0 7231.8 5821.6 7213.5 6811.7 11638.2 7494.7 14215.0 2974.6 1469.9 3536.8 7040.7 7075.1 1092.8 703.6 12784.4 10055.1 11086.8 9616.5 6982.9 8574.9 16180.0 EEF2 "EEF-2, EF2" ENSG00000167658 "Eukaryotic translation elongation factor 2" P13639 19 3976056-3985463 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007795, HPA040534, HPA057351" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 17000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Plasma membrane, Cytosol" "CAB007795: AB_598149, HPA040534: AB_2677024, HPA057351: AB_2683417" "unprognostic (5.47e-2)" "unprognostic (9.59e-2)" "unprognostic (3.75e-1)" "prognostic favorable (1.81e-6)" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.11e-1)" "unprognostic (1.83e-1)" "unprognostic (1.77e-2)" "unprognostic (1.25e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.25e-5)" "unprognostic (4.46e-2)" "unprognostic (5.60e-2)" "unprognostic (6.82e-2)" "unprognostic (9.86e-2)" 1022.6 1037.0 771.8 507.3 755.2 920.3 946.7 737.2 1059.6 966.7 807.6 1122.4 821.4 887.6 563.7 1062.3 857.3 501.2 1396.6 740.9 729.1 843.2 1152.9 666.9 685.4 775.4 769.6 1627.6 3194.1 494.0 838.0 386.2 782.3 819.2 344.5 224.7 1276.4 500.3 2322.6 1142.7 798.9 385.4 758.3 721.6 1266.6 490.5 762.7 541.0 793.6 1112.4 499.0 927.8 797.7 745.1 1456.8 1018.4 579.3 1539.4 1515.6 2706.7 830.9 1110.4 1479.8 1036.7 1012.7 1618.1 652.7 3000.6 644.1 1032.3 461.1 1069.8 919.4 1719.4 544.2 755.0 1533.0 768.5 919.9 1677.0 2204.8 1668.0 1277.6 3515.5 1777.2 916.0 1404.1 1497.5 1086.6 1434.4 1526.7 2145.4 642.1 2095.7 1510.1 1266.3 1537.0 518.3 1015.7 1654.2 860.3 1938.3 871.2 1270.2 1575.4 1466.4 699.0 1377.1 2058.3 543.1 1344.7 1992.7 1321.8 738.2 765.7 1521.4 1738.7 2276.4 1644.3 1485.3 1100.4 2065.8 986.6 81.2 455.7 64.1 259.8 333.1 460.2 578.5 453.0 344.6 430.7 478.1 497.2 404.1 43.1 355.3 342.1 358.7 429.4 756.5 771.8 755.2 737.2 1059.6 740.9 729.1 775.4 769.6 782.3 758.3 762.7 745.1 323.1 221.2 392.2 24.5 1125.5 1321.1 1071.3 754.3 1269.7 212.6 981.3 694.3 627.9 597.7 448.3 255.6 77.2 958.1 535.9 556.9 986.1 716.0 799.2 318.2 675.4 568.2 744.2 934.8 23.2 1816.8 1305.0 679.7 619.3 428.5 373.4 596.1 656.8 690.6 610.1 203.6 28.9 982.1 411.0 885.4 859.5 1195.6 1008.4 514.2 645.7 36.5 907.5 429.1 614.8 27.2 42.2 868.2 815.5 832.8 992.8 1010.5 1562.7 1078.8 194.5 134.1 585.1 797.7 697.3 371.5 308.4 1343.0 1347.1 1243.1 727.1 1044.3 1168.4 1051.6 EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 472.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 942.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.4;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 266.5;HaCaT: 95.5;SiHa: 156.9;SK-BR-3: 227.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" NA Yes 2800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" 43.2 24.0 25.6 4.9 30.0 1.3 64.7 27.2 33.9 31.7 21.8 42.5 57.9 23.7 28.5 54.7 23.2 24.5 47.1 25.5 25.9 73.8 472.8 86.7 8.1 31.0 29.0 17.5 53.6 29.7 19.5 109.9 29.8 79.5 51.6 7.8 66.6 22.1 18.5 123.1 69.3 13.4 27.8 8.6 40.7 4.1 27.6 21.0 79.9 38.6 12.5 36.9 55.5 35.2 15.1 5.9 0.9 11.5 2.1 0.1 266.5 0.0 0.5 0.2 0.3 13.9 32.0 0.0 26.3 0.0 9.0 95.5 6.6 35.3 0.2 9.8 2.2 0.1 19.0 76.1 0.9 0.2 1.5 4.9 84.5 0.0 30.2 7.3 53.6 0.9 2.8 0.3 0.0 52.2 0.3 1.1 1.7 52.3 17.7 6.1 1.5 9.3 66.4 22.4 9.8 14.2 156.9 227.1 6.0 48.8 51.1 0.0 6.7 0.1 9.1 0.6 1.5 2.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 1.0 0.7 0.0 0.3 11.4 5.9 0.4 0.4 0.0 0.0 0.0 1.6 25.6 30.0 27.2 33.9 25.5 25.9 31.0 29.0 29.8 27.8 27.6 35.2 116.8 198.7 113.1 0.7 2.3 127.7 103.7 91.6 327.8 3.0 198.3 151.9 47.8 95.8 101.2 18.4 0.0 195.6 4.4 265.0 13.7 130.1 0.3 100.4 19.1 148.9 18.6 4.0 0.7 63.9 942.6 23.2 124.9 163.5 6.3 0.1 106.4 133.2 28.2 5.0 0.8 114.1 101.7 4.3 19.5 0.7 4.7 4.2 62.2 2.8 0.6 5.7 0.0 3.5 28.7 73.9 205.5 0.4 4.1 197.8 238.6 34.5 54.5 1.1 0.0 6.5 35.9 0.8 2.6 253.2 217.8 254.2 7.5 1.3 95.9 135.9 EFNA2 "ELF-1, EPLG6, LERK6" ENSG00000099617 "Ephrin A2" O43921 19 1285873-1301431 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.3;liver: 12.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.5;Cardiomyocytes: 4.9;Inhibitory neurons: 1.6;Oligodendrocyte precursor cells: 5.0;Paneth cells: 2.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.5;stomach cancer: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 10.3;CACO-2: 6.2;Hep G2: 13.5;NTERA-2: 6.8;OE19: 6.0;REH: 6.8;SH-SY5Y: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067567 Approved Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 43: Cardiomyocytes - Nuclear processes" "Mitochondria, Cytosol" "HPA067567: AB_2732771" "unprognostic (1.98e-1)" "unprognostic (3.26e-1)" "unprognostic (2.87e-3)" "unprognostic (1.96e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-1)" "unprognostic (7.19e-2)" "unprognostic (2.34e-3)" "unprognostic (3.58e-2)" "unprognostic (6.82e-2)" "unprognostic (8.48e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-3)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-4)" "unprognostic (1.94e-1)" 0.0 0.0 1.6 1.5 1.7 0.0 0.0 1.2 1.3 0.1 0.3 9.9 9.9 0.0 0.0 0.4 0.0 3.5 0.0 1.4 2.0 0.4 12.9 0.0 0.0 1.7 3.0 0.0 0.1 0.2 0.3 0.2 1.1 0.0 4.4 0.6 0.0 0.0 0.2 0.1 12.3 0.0 1.9 0.0 0.2 0.6 3.1 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.2 10.3 3.1 0.0 0.0 3.7 0.2 0.0 0.0 0.0 6.2 0.1 0.0 1.8 0.0 0.0 0.0 4.8 0.0 0.0 0.0 1.4 0.0 0.0 13.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.1 0.1 0.1 0.0 1.4 0.0 0.1 6.8 6.0 0.0 6.8 1.0 0.1 0.0 0.4 0.0 13.3 0.7 0.0 0.2 3.5 0.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.6 1.7 1.2 1.3 1.4 2.0 1.7 3.0 1.1 1.9 3.1 1.4 0.1 0.0 0.0 1.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 1.0 0.0 2.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.2 0.0 EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376894-107670937 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Astrocytes: 291.2;Excitatory neurons: 798.5;Inhibitory neurons: 373.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 35.2;RPTEC TERT1: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol NA Yes 10000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "CAB013282: AB_2533353, HPA054047: AB_2682355" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.15e-3)" "unprognostic (3.98e-3)" "unprognostic (2.74e-2)" "unprognostic (8.91e-4)" "unprognostic (9.46e-3)" "unprognostic (4.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.26e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.92e-7)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (1.27e-1)" 4.1 1.1 4.5 2.0 6.5 0.1 4.0 1.3 13.6 10.1 0.0 2.3 0.8 1.1 2.0 7.1 2.9 2.7 6.8 3.1 10.2 3.4 0.3 2.4 0.8 0.9 0.3 4.0 0.5 2.5 2.7 2.4 0.6 4.3 2.3 2.5 5.6 4.7 0.5 9.7 0.8 2.2 0.0 5.3 2.5 1.4 2.1 1.4 1.0 1.4 2.5 3.5 4.8 5.4 12.7 22.2 35.2 0.0 16.7 14.2 3.6 0.3 6.3 4.5 11.6 0.2 13.9 0.0 20.5 2.4 7.1 13.1 19.4 18.0 3.6 0.0 12.9 0.1 11.9 0.0 3.1 0.6 0.0 16.0 15.4 0.0 14.4 3.9 13.8 0.0 0.0 0.0 8.3 12.0 0.0 0.0 4.6 0.1 1.9 0.0 16.9 0.4 50.9 15.5 5.8 14.7 6.0 8.9 3.8 11.2 3.9 2.2 0.2 28.3 5.0 17.4 7.1 1.2 0.0 8.3 12.4 0.8 31.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 4.5 6.5 1.3 13.6 3.1 10.2 0.9 0.3 0.6 0.0 2.1 5.4 1.1 9.6 24.4 291.2 0.0 15.9 22.5 18.5 6.2 4.3 11.8 8.5 30.6 11.5 26.0 14.7 0.0 20.3 3.3 4.3 23.5 1.7 1.8 3.2 14.8 8.2 12.0 0.0 798.5 1.3 3.3 16.9 5.6 6.3 0.0 0.1 9.7 0.0 1.7 6.7 373.1 8.5 18.3 0.3 7.0 3.7 18.3 0.4 8.8 37.5 3.6 4.7 2.1 26.2 8.7 13.9 4.9 21.8 1.7 14.1 0.0 0.1 19.6 1.4 0.0 1.3 3.7 0.1 4.0 14.9 24.2 3.8 2.2 2.3 5.9 23.1 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 239.7;Hepatic stellate cells: 187.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.5;OE19: 45.5;SH-SY5Y: 42.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" 20.7 6.1 3.8 4.3 5.9 0.2 17.1 1.3 6.2 11.0 0.0 22.1 7.9 10.2 0.7 12.1 8.8 4.2 15.5 5.5 4.9 11.2 4.8 23.4 3.2 0.1 0.1 7.2 3.9 3.2 6.3 15.4 0.3 12.5 9.9 3.2 14.0 10.6 6.5 17.2 14.4 5.5 0.1 7.4 15.0 5.4 1.6 3.6 11.9 8.0 3.2 6.5 14.1 4.3 23.3 1.8 76.5 0.1 0.2 0.7 0.3 10.8 5.4 8.2 4.7 19.1 28.7 0.0 11.0 2.5 0.6 28.4 2.9 10.9 8.9 0.0 24.3 0.1 6.0 0.0 1.5 6.9 0.6 3.5 19.0 0.4 16.1 4.1 10.4 0.2 0.1 0.0 9.1 3.3 0.2 0.1 4.7 45.5 5.0 21.9 3.3 0.1 11.9 2.5 5.8 42.7 3.6 1.7 0.1 21.4 1.0 0.2 9.6 16.3 0.0 0.5 23.8 0.4 0.0 0.0 34.5 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 5.9 1.3 6.2 5.5 4.9 0.1 0.1 0.3 0.1 1.6 4.3 239.7 6.4 35.7 38.8 4.4 83.2 52.9 15.4 13.1 10.4 39.8 45.3 8.8 5.7 13.2 25.8 0.0 1.4 8.6 114.6 0.0 6.8 0.4 24.7 69.8 106.5 50.6 0.0 49.3 1.4 3.1 15.4 69.3 42.1 17.8 11.8 187.4 1.3 1.1 6.7 29.7 59.8 26.4 5.8 11.9 1.0 0.3 4.0 32.0 48.7 0.0 89.1 0.0 3.5 13.9 46.3 64.3 0.4 1.0 25.1 15.9 0.2 8.7 3.4 0.0 33.1 22.8 0.7 3.3 41.1 86.0 1.9 7.9 6.4 71.5 72.0 EFNB3 "EPLG8, LERK-8" ENSG00000108947 "Ephrin B3" Q15768 17 7705202-7711372 "Cancer-related genes, Predicted membrane proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 11.6;Early spermatids: 9.2;Excitatory neurons: 9.1" "Cancer enhanced" "Detected in many" "glioma: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.9;AN3-CA: 32.3;hTERT-RPE1: 32.6;SH-SY5Y: 28.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001623 Approved NA NA 11000 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA001623: AB_1848026" "unprognostic (5.17e-2)" "unprognostic (7.15e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.52e-4)" "unprognostic (3.27e-1)" "unprognostic (1.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.21e-4)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.00e-1)" "unprognostic (8.56e-2)" "unprognostic (2.20e-2)" 3.5 2.0 23.1 0.7 25.8 0.0 3.5 0.1 25.3 7.4 5.6 0.7 0.3 10.3 0.5 2.0 5.5 1.2 1.1 23.0 37.3 1.2 1.7 1.0 0.3 9.2 10.7 4.7 1.2 12.0 5.7 1.2 8.7 2.1 0.6 3.6 1.4 0.5 0.3 5.9 0.9 3.7 5.8 0.1 0.8 3.6 38.2 0.4 0.7 0.1 0.9 1.0 2.4 10.7 0.0 1.0 53.9 32.3 1.0 0.7 0.4 0.6 7.2 4.8 3.1 2.0 3.4 0.0 1.1 2.1 0.3 0.4 13.9 6.9 2.8 0.0 6.8 0.2 0.0 0.1 1.5 0.0 0.0 3.1 1.4 1.5 1.1 32.6 0.3 0.5 0.0 0.0 0.9 5.4 0.0 0.0 4.8 0.0 1.0 0.2 0.1 0.0 7.4 0.7 3.4 28.1 0.0 0.0 1.1 9.4 2.9 0.0 0.1 3.2 10.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 25.8 0.1 25.3 23.0 37.3 9.2 10.7 8.7 5.8 38.2 10.7 2.1 0.0 0.0 1.0 0.2 4.1 3.8 4.6 6.8 2.2 5.9 11.6 1.7 1.5 0.9 0.0 0.0 0.3 0.0 0.1 0.0 1.1 9.2 2.5 5.9 1.3 6.7 2.7 9.1 0.2 1.0 4.6 0.0 0.7 1.3 3.3 2.2 0.0 0.4 5.0 6.8 0.3 4.1 0.0 0.4 5.6 4.7 0.2 0.0 1.0 0.0 1.4 0.0 0.5 1.3 0.2 0.0 3.4 0.0 1.6 0.0 0.0 6.0 0.7 0.0 0.0 2.2 0.7 0.7 1.8 2.8 0.3 0.1 1.2 0.0 1.6 EGF ENSG00000138798 "Epidermal growth factor" P01133 4 109912883-110013766 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 110.2;pancreas: 89.5;skeletal muscle: 29.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.9;Breast myoepithelial cells: 8.1;Cardiomyocytes: 8.2;Distal tubular cells: 7.9;Excitatory neurons: 8.5;Inhibitory neurons: 11.2;Muller glia cells: 26.2;Skeletal myocytes: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.4;SK-BR-3: 11.6;U-251 MG: 3.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 209000 680000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (2.83e-2)" "unprognostic (1.02e-2)" "unprognostic (8.50e-3)" "unprognostic (1.88e-3)" "unprognostic (4.24e-2)" "unprognostic (1.64e-3)" "unprognostic (5.06e-4)" "unprognostic (8.30e-2)" "unprognostic (2.21e-3)" "unprognostic (4.25e-2)" "unprognostic (1.80e-2)" "unprognostic (2.95e-1)" "unprognostic (7.72e-3)" "unprognostic (4.64e-5)" "unprognostic (2.63e-1)" "unprognostic (9.80e-5)" "unprognostic (3.92e-3)" 0.0 0.0 1.0 0.1 1.0 0.2 14.7 0.2 0.8 0.0 0.2 0.8 0.0 0.4 2.4 0.7 0.3 1.0 2.8 0.9 2.0 110.2 0.0 0.5 0.0 1.4 0.9 0.0 89.5 0.2 0.4 0.0 1.5 1.4 1.1 13.6 15.7 0.4 29.6 0.7 0.2 0.5 1.2 0.1 0.0 0.1 0.7 0.0 3.0 17.4 0.0 0.4 0.1 1.8 0.2 0.2 1.9 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.4 0.1 0.0 0.0 6.4 0.6 1.6 0.0 0.3 0.0 0.4 0.0 0.3 0.1 0.6 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.1 0.6 0.1 0.0 0.0 2.3 0.0 0.4 0.1 0.1 0.5 0.4 0.2 0.0 0.0 0.0 11.6 0.4 1.2 2.8 0.0 0.0 0.9 1.3 0.0 3.6 0.0 0.0 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.0 1.0 0.2 0.8 0.9 2.0 1.4 0.9 1.5 1.2 0.7 1.8 0.1 0.0 0.0 3.3 0.0 1.0 0.2 0.1 0.0 1.0 12.9 8.1 8.2 0.0 0.5 0.0 0.0 0.0 0.2 2.0 7.9 0.2 5.6 0.2 0.1 0.6 0.0 0.0 8.5 5.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 11.2 0.1 0.0 0.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 26.2 0.0 1.5 0.3 1.0 0.4 0.0 0.0 1.1 0.1 1.2 1.0 1.2 0.0 8.2 0.2 0.5 0.4 0.0 1.4 0.0 0.1 0.1 1.6 0.3 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EGR1 "AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225" ENSG00000120738 "Early growth response 1" P18146 5 138465479-138469303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 1113.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 133.1" "Immune cell enhanced" "Detected in some" "neutrophil: 7.1" "Group enriched" "Detected in many" 7 "granulocytes: 7.1;monocytes: 3.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 192.0;hTCEpi: 286.6;U-266/84: 478.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019427, HPA029937, HPA029938" Supported Enhanced Nucleoplasm No No "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB019427: AB_2097038, HPA029937: AB_2673258, HPA029938: AB_2673259" "unprognostic (5.47e-2)" "unprognostic (4.09e-1)" "unprognostic (1.57e-1)" "unprognostic (7.74e-2)" "unprognostic (6.32e-2)" "unprognostic (2.66e-1)" "unprognostic (1.80e-1)" "unprognostic (2.96e-1)" "unprognostic (7.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.75e-1)" "unprognostic (2.94e-2)" "unprognostic (3.51e-3)" "unprognostic (3.57e-2)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (1.98e-3)" 565.5 354.0 7.5 135.4 15.9 176.7 173.9 133.1 70.1 302.5 10.0 246.5 54.8 197.6 13.5 370.9 911.7 345.2 258.8 20.7 30.4 173.2 149.5 173.4 145.2 9.9 13.2 974.6 137.0 93.5 243.3 54.2 12.9 309.7 161.1 56.0 140.9 84.4 66.0 363.1 107.2 474.3 4.4 77.5 254.5 26.9 10.4 301.5 584.4 354.9 19.1 191.4 115.9 19.5 21.8 0.9 45.0 67.6 119.6 192.0 5.1 36.7 22.7 48.4 39.0 26.4 18.9 1.1 5.9 80.2 165.8 10.1 2.6 74.5 22.2 1.1 3.3 3.0 11.5 7.6 15.5 8.0 57.8 15.2 286.6 43.2 9.8 37.6 4.2 53.9 112.5 26.0 14.3 108.2 3.2 34.1 4.1 80.3 0.1 0.8 6.7 4.1 36.8 13.1 56.5 6.4 44.7 120.1 106.6 43.3 1.5 6.6 1.8 17.5 22.6 8.7 14.2 60.1 478.8 8.6 20.3 103.5 5.2 0.0 2.6 0.3 0.1 3.6 0.0 0.7 0.1 0.0 0.7 0.2 0.1 0.1 7.1 0.1 1.2 0.0 0.2 0.5 7.5 15.9 133.1 70.1 20.7 30.4 9.9 13.2 12.9 4.4 10.4 19.5 920.4 275.7 485.6 6.8 116.4 181.8 719.6 207.4 816.1 43.5 550.0 459.0 652.4 420.4 124.0 29.5 64.6 159.5 46.2 645.2 7.9 255.4 1.4 356.0 836.5 383.1 960.5 27.3 20.3 101.7 110.1 989.9 736.0 645.4 354.0 274.8 347.0 183.1 131.4 3.3 2.7 747.6 93.6 218.6 109.7 3.8 164.7 300.7 106.7 20.6 8.6 191.6 0.0 1.5 2.4 135.3 380.8 53.0 67.2 405.1 224.8 5.7 127.4 101.3 223.5 1113.1 613.2 3.2 2.9 644.8 200.3 129.7 83.4 104.9 480.2 145.4 EI24 "EPG4, PIG8, TP53I8" ENSG00000149547 "EI24 autophagy associated transmembrane protein" O14681 11 125569280-125584684 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 461.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 575.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 760.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047165, HPA051029" Approved Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "Golgi apparatus" "HPA047165: AB_2679965, HPA051029: AB_2681317" "unprognostic (2.04e-3)" "unprognostic (2.69e-2)" "unprognostic (1.25e-2)" "unprognostic (3.43e-2)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.02e-2)" "unprognostic (6.38e-2)" "unprognostic (6.74e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (4.58e-2)" "unprognostic (8.35e-2)" "unprognostic (2.07e-1)" "unprognostic (3.01e-1)" 53.4 32.6 61.1 36.2 62.5 23.2 72.6 59.7 72.4 51.3 59.8 77.8 49.6 46.2 57.4 80.8 50.8 46.3 55.7 60.2 61.5 61.0 248.4 45.0 28.4 60.2 62.5 42.4 101.8 461.9 30.6 48.5 60.2 49.6 80.4 39.4 75.3 58.0 119.5 70.2 49.3 62.5 62.4 30.5 59.7 33.1 64.4 35.3 40.5 104.6 42.3 78.9 48.4 61.0 156.6 115.6 129.5 160.5 207.7 155.9 162.4 159.6 116.8 104.3 93.4 178.9 303.4 158.0 264.0 146.5 110.8 176.1 199.0 326.8 135.2 42.0 142.6 760.9 77.2 179.9 154.1 170.9 78.4 147.5 292.7 157.4 230.2 102.8 223.9 85.1 351.1 61.1 149.4 113.8 79.0 96.4 173.6 398.3 139.5 113.9 155.4 132.8 177.0 272.4 120.1 116.9 187.1 215.5 63.4 212.3 436.4 165.7 195.2 133.8 93.3 94.7 128.7 39.7 84.8 200.5 58.5 256.1 182.2 4.3 7.0 5.9 7.2 6.7 7.2 8.4 5.7 9.0 10.9 6.3 8.1 6.7 0.8 6.5 4.9 14.5 9.1 5.3 61.1 62.5 59.7 72.4 60.2 61.5 60.2 62.5 60.2 62.4 64.4 61.0 73.5 32.1 38.3 13.4 34.8 120.6 130.3 132.6 120.1 58.9 148.8 100.6 61.9 124.4 69.5 110.3 37.5 166.9 32.4 66.4 144.8 178.6 31.1 34.4 59.3 87.1 98.4 102.7 25.1 181.8 201.2 80.1 87.7 46.5 27.3 76.2 74.6 575.0 110.5 82.4 24.0 115.3 105.8 49.8 96.1 49.7 71.4 40.9 90.7 11.2 40.9 107.1 50.4 13.0 23.0 182.1 67.6 72.2 79.1 270.0 68.5 122.7 43.9 36.9 46.0 60.8 80.1 95.9 112.3 176.3 181.4 140.1 31.0 71.3 135.7 189.4 EIF2S2 "EIF2, EIF2beta, PPP1R67" ENSG00000125977 "Eukaryotic translation initiation factor 2 subunit beta" P20042 20 34088309-34112243 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034415, HPA041262, HPA041332" Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 480000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" Nucleoli "CAB034415: AB_2095998, HPA041262: AB_2677381, HPA041332: AB_2677417" "unprognostic (5.76e-3)" "unprognostic (7.12e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (8.74e-4)" "unprognostic (1.02e-1)" "unprognostic (1.47e-3)" "prognostic unfavorable (3.23e-5)" "unprognostic (9.36e-3)" "unprognostic (2.39e-1)" "unprognostic (6.55e-3)" "unprognostic (3.04e-3)" "unprognostic (1.25e-2)" "prognostic unfavorable (9.64e-10)" "unprognostic (2.52e-2)" "unprognostic (1.82e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-2)" 50.7 49.2 40.1 44.0 42.1 45.0 42.3 43.1 54.5 34.8 39.8 45.8 38.3 33.7 37.9 61.2 30.6 32.5 46.2 39.0 41.7 54.0 59.2 46.8 52.8 44.3 41.3 32.0 81.4 35.8 27.7 54.2 43.9 35.0 42.8 23.7 43.5 33.9 100.8 39.0 37.6 40.5 43.6 37.9 50.8 37.1 41.6 46.6 42.4 64.0 56.3 63.1 37.9 48.4 211.9 139.1 103.4 125.5 99.1 149.3 196.6 188.7 180.2 184.1 184.6 493.4 144.5 188.5 135.1 171.9 204.1 194.5 169.7 310.6 222.0 61.0 92.3 373.8 110.0 254.5 254.7 241.9 116.7 153.6 259.1 182.7 270.2 125.8 195.5 273.7 223.6 174.8 153.5 135.8 226.0 201.3 100.6 243.7 251.1 128.2 176.0 176.2 145.5 174.2 104.7 71.3 209.3 125.2 403.7 119.2 189.9 282.4 132.8 208.7 129.0 132.5 179.8 162.4 153.8 195.9 196.5 185.0 155.1 54.2 77.1 64.8 54.7 89.0 68.1 84.8 77.2 77.2 75.8 71.2 72.0 72.8 47.3 74.9 83.8 105.3 96.1 64.0 40.1 42.1 43.1 54.5 39.0 41.7 44.3 41.3 43.9 43.6 41.6 48.4 157.4 169.9 162.1 13.7 167.8 180.5 326.3 384.9 81.4 60.5 171.7 154.6 145.1 223.1 241.7 139.8 31.3 359.2 139.6 145.7 307.2 344.2 314.9 182.9 160.1 199.2 126.7 300.7 17.6 529.2 394.4 128.5 110.6 139.1 144.4 80.1 253.4 497.1 243.0 42.1 17.1 229.6 215.7 223.1 119.3 163.7 126.5 147.0 119.2 16.9 286.8 92.8 126.7 17.1 25.2 519.3 133.8 129.4 182.6 292.7 141.5 335.0 207.7 95.3 111.7 102.6 226.6 446.4 211.6 132.7 174.5 641.7 124.0 220.6 200.4 343.8 EIF3E "eIF3-p48, EIF3S6, INT6" ENSG00000104408 "Eukaryotic translation initiation factor 3 subunit E" P60228 8 108162787-108443496 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023973 Approved Supported Cytosol NA NA 21000 "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA023973: AB_1848083" "unprognostic (8.18e-2)" "unprognostic (4.28e-2)" "unprognostic (6.26e-2)" "unprognostic (1.51e-1)" "unprognostic (3.52e-3)" "unprognostic (6.93e-3)" "unprognostic (2.29e-2)" "unprognostic (2.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.96e-1)" "unprognostic (1.67e-3)" "unprognostic (3.63e-1)" "prognostic unfavorable (3.06e-7)" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.77e-2)" 269.0 201.4 104.7 94.2 107.2 251.7 418.1 113.6 178.1 360.4 110.9 281.2 93.5 232.5 243.3 256.3 263.0 163.5 187.7 104.6 110.0 178.0 199.1 174.2 231.1 107.7 108.9 449.4 409.1 138.5 157.2 161.1 111.2 204.8 155.7 63.6 214.1 186.4 343.2 230.9 181.7 135.6 107.3 157.6 237.0 83.9 107.6 283.0 183.9 241.1 208.9 248.7 267.2 112.7 339.4 208.1 211.3 193.3 518.2 1098.8 139.9 193.0 430.3 415.4 443.0 238.0 260.1 653.0 213.0 288.6 134.2 187.6 421.1 507.6 502.6 216.1 485.0 595.8 218.6 472.3 357.6 287.5 169.0 813.2 745.9 272.8 678.6 534.7 636.8 405.6 477.5 196.8 469.6 453.7 384.2 898.4 196.2 577.7 403.6 300.6 278.8 436.6 520.0 305.2 223.5 192.2 122.0 78.0 363.2 288.2 263.8 413.7 279.1 131.7 241.7 139.9 201.9 167.4 171.6 426.5 171.6 483.1 149.8 79.5 165.6 32.6 104.0 161.0 197.1 214.7 205.5 148.4 218.7 178.0 301.0 225.9 14.6 166.8 153.1 116.6 202.5 317.3 104.7 107.2 113.6 178.1 104.6 110.0 107.7 108.9 111.2 107.3 107.6 112.7 216.8 134.6 204.6 36.9 565.3 1036.0 1105.8 1174.4 805.3 64.5 569.8 274.2 93.1 317.4 463.5 158.2 54.2 614.4 288.0 101.3 606.5 332.3 377.4 173.8 399.2 365.6 297.5 319.8 36.3 354.3 770.9 366.9 196.7 220.5 378.3 277.1 403.4 212.6 424.2 58.9 36.2 400.5 443.5 662.4 875.2 73.8 454.2 368.7 517.6 37.5 621.8 154.8 268.8 59.8 69.2 272.3 279.1 327.6 251.0 728.2 273.8 799.7 201.7 74.6 190.7 434.6 564.5 276.7 102.8 532.6 1117.1 620.3 488.1 490.0 568.6 914.3 EIF3H "eIF3-gamma, eIF3-p40, EIF3S3" ENSG00000147677 "Eukaryotic translation initiation factor 3 subunit H" O15372 8 116642130-116766925 "Cancer-related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 1808.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023117, HPA023553" Approved Approved Cytosol NA NA 38000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA023117: AB_1848076, HPA023553: AB_1848077" "prognostic unfavorable (5.26e-4)" "prognostic unfavorable (8.07e-4)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (6.69e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (8.34e-4)" "unprognostic (3.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-3)" "unprognostic (3.08e-1)" "unprognostic (3.77e-2)" "unprognostic (6.36e-2)" "unprognostic (1.48e-1)" "unprognostic (9.19e-2)" "unprognostic (1.11e-1)" 212.3 164.1 111.0 168.6 119.8 341.1 246.8 114.8 138.5 270.2 104.2 233.1 172.7 212.7 180.0 232.0 211.3 159.2 223.6 106.9 121.0 184.2 181.0 149.2 283.2 118.4 113.7 392.6 249.9 184.0 147.6 161.7 120.6 179.5 201.9 131.0 219.9 158.1 372.6 201.8 167.9 182.5 124.2 171.4 195.2 144.4 111.9 291.0 215.5 278.3 307.1 221.7 237.0 130.2 455.0 256.2 302.2 264.9 390.3 678.0 300.4 292.5 374.4 316.7 306.5 266.1 521.6 719.4 288.6 307.2 230.4 284.4 335.5 445.2 395.5 468.5 271.9 636.0 212.0 400.6 487.8 278.1 325.7 630.0 606.4 287.0 659.5 536.4 348.8 555.5 548.2 370.1 360.4 335.7 778.2 388.1 308.6 995.6 404.5 443.6 201.8 517.6 479.8 327.8 341.6 412.4 153.5 1808.1 504.9 294.8 538.3 550.5 322.5 201.8 374.5 301.5 388.8 591.3 574.4 591.3 280.2 483.4 281.8 165.2 361.6 132.2 217.9 356.8 358.9 438.1 393.5 317.9 468.6 381.4 511.0 432.1 74.4 314.6 366.1 260.9 477.7 585.7 111.0 119.8 114.8 138.5 106.9 121.0 118.4 113.7 120.6 124.2 111.9 130.2 138.9 182.7 210.7 42.4 314.6 337.5 423.7 444.2 266.9 62.7 317.2 273.4 160.8 191.6 253.0 93.8 12.5 488.0 211.4 117.0 448.0 290.5 387.2 81.2 196.0 185.8 201.0 215.8 47.8 380.5 551.0 183.7 125.9 159.2 194.4 166.2 168.8 104.6 332.4 26.9 49.9 301.6 170.9 386.6 402.8 265.0 331.5 261.5 209.9 51.5 509.9 136.0 224.6 58.3 70.3 292.9 240.5 220.1 166.7 338.5 260.2 443.9 92.9 76.8 197.2 251.5 504.1 233.0 176.0 317.4 356.5 577.2 287.5 241.4 345.5 481.2 EIF4A2 "BM-010, DDX2B, EIF4A, EIF4F" ENSG00000156976 "Eukaryotic translation initiation factor 4A2" Q14240 3 186783205-186789897 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Helicase, Hydrolase, Initiation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011690, HPA068286" Uncertain Approved Cytosol NA NA 1600000 "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB011690: AB_732123, HPA068286: AB_2685968" "unprognostic (1.49e-1)" "unprognostic (9.62e-2)" "unprognostic (3.78e-2)" "unprognostic (9.50e-3)" "unprognostic (2.82e-2)" "unprognostic (1.10e-2)" "unprognostic (4.46e-2)" "unprognostic (6.27e-2)" "unprognostic (4.32e-3)" "unprognostic (1.00e-1)" "unprognostic (6.39e-2)" "unprognostic (3.99e-2)" "unprognostic (6.36e-2)" "unprognostic (3.22e-1)" "unprognostic (3.03e-1)" "unprognostic (4.67e-2)" "unprognostic (2.62e-2)" 178.4 288.5 277.5 105.8 302.9 7.3 243.4 328.0 388.2 274.5 251.6 282.5 143.3 325.0 196.3 178.1 322.0 205.3 383.9 309.0 331.3 287.8 202.6 156.2 192.3 275.4 254.5 606.8 272.1 189.2 292.5 218.8 290.2 249.7 179.7 310.3 213.5 262.9 675.3 93.7 165.7 252.8 270.6 159.0 196.0 155.3 316.9 178.0 293.8 553.2 170.0 224.3 186.8 275.6 95.4 44.6 179.1 30.2 624.9 589.3 59.3 158.9 138.5 159.1 202.1 159.9 34.2 200.0 812.8 213.7 283.4 146.8 255.2 66.5 272.0 182.6 134.8 304.8 54.4 214.5 249.6 68.3 209.0 402.5 291.8 47.8 368.3 764.1 275.2 161.6 109.6 311.9 496.8 14.2 112.5 31.2 183.7 337.0 199.4 143.3 124.1 122.2 305.9 110.4 331.8 71.9 241.4 175.4 356.9 427.3 269.6 244.3 205.6 122.8 63.0 123.9 87.7 252.1 374.8 85.9 86.9 71.0 63.9 233.4 78.5 88.5 125.8 87.5 200.8 245.4 183.2 154.5 91.0 203.0 273.4 224.2 50.5 169.6 125.3 85.4 187.3 282.3 277.5 302.9 328.0 388.2 309.0 331.3 275.4 254.5 290.2 270.6 316.9 275.6 265.3 118.6 220.2 68.6 416.9 690.3 770.9 595.8 412.6 267.4 396.7 308.2 271.3 327.5 447.9 261.1 64.6 450.1 370.8 306.7 661.2 254.3 33.0 287.9 297.5 319.2 407.8 221.4 146.8 94.5 251.2 367.8 250.2 344.2 312.1 267.2 258.1 142.4 226.6 390.3 138.0 372.9 455.7 228.6 385.2 56.8 385.8 242.9 345.1 92.8 318.1 383.9 256.4 73.9 118.7 136.0 410.8 472.8 235.7 737.4 567.9 665.2 337.8 192.8 236.7 409.7 489.9 223.8 165.4 314.8 618.0 615.5 449.2 345.6 380.1 879.5 EIF4E "EIF4E1, EIF4EL1, EIF4F" ENSG00000151247 "Eukaryotic translation initiation factor 4E" P06730 4 98879276-98929133 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Autism, Autism spectrum disorder, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 927.0;Late spermatids: 2284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004077, CAB016316, HPA068358" Supported Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA 450000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Cytosol, Cytoplasmic bodies" Nucleoplasm "CAB004077: AB_823488, CAB016316: AB_627502, HPA068358: " "unprognostic (3.07e-3)" "unprognostic (1.43e-1)" "unprognostic (6.53e-3)" "unprognostic (7.52e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-3)" "unprognostic (2.03e-5)" "unprognostic (6.55e-3)" "unprognostic (1.09e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.63e-1)" "unprognostic (1.10e-3)" "unprognostic (5.40e-2)" "unprognostic (1.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" 38.0 37.4 27.4 37.7 28.5 57.4 35.6 32.5 34.6 28.5 20.9 45.1 35.9 30.5 38.0 51.7 31.7 31.3 37.5 27.8 34.3 47.4 43.3 27.0 44.6 29.2 31.1 29.1 27.0 45.1 17.0 35.9 29.2 31.4 52.2 54.0 31.2 30.7 39.2 24.2 34.4 39.4 36.2 31.5 35.8 62.6 31.4 53.2 52.6 48.1 58.0 54.4 29.8 34.3 101.1 85.2 139.8 96.5 73.4 74.2 87.3 184.6 105.3 137.0 100.5 111.0 122.7 194.7 59.4 104.4 94.3 49.0 181.9 124.9 158.9 133.5 56.2 135.6 52.7 105.8 62.6 199.3 104.8 54.5 78.3 104.8 82.9 81.5 108.3 97.6 226.6 95.2 120.0 82.9 189.2 110.6 115.0 189.2 72.2 119.7 94.4 90.0 122.0 85.3 123.3 80.3 85.5 188.4 65.4 93.3 89.9 85.9 86.5 110.0 121.6 96.9 153.7 71.4 185.4 179.4 99.7 102.7 127.1 39.5 34.7 59.3 38.2 42.1 44.4 50.0 43.2 40.2 39.6 43.6 47.3 47.3 26.3 54.3 54.8 33.5 46.5 50.3 27.4 28.5 32.5 34.6 27.8 34.3 29.2 31.1 29.2 36.2 31.4 34.3 45.2 32.1 42.2 29.7 93.1 362.1 227.5 202.2 149.7 87.9 81.6 41.1 27.5 55.8 106.0 60.7 35.5 105.3 56.2 140.5 256.3 88.9 927.0 76.1 84.0 77.8 64.6 192.8 45.2 67.4 150.0 87.1 80.0 119.0 51.4 28.0 40.0 77.1 121.1 85.8 45.0 77.4 227.9 61.9 327.6 2284.9 50.7 122.1 193.9 25.3 69.8 82.0 57.7 35.2 50.9 83.8 107.1 49.2 113.0 191.1 83.2 189.2 76.8 64.7 52.6 78.7 151.7 98.7 87.1 171.2 370.9 119.0 82.2 39.8 97.3 224.3 EIF4EBP1 "4E-BP1, PHAS-I" ENSG00000187840 "Eukaryotic translation initiation factor 4E binding protein 1" Q13541 8 38030534-38060365 "Cancer-related genes, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 188.9;salivary gland: 164.2" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 730.0;Pancreatic endocrine cells: 277.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005032, CAB005039, HPA023501" Supported Supported Nucleoplasm,Cytosol NA NA 44000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "CAB005032: AB_562030, CAB005039: AB_562029, HPA023501: AB_1848095" "unprognostic (1.55e-2)" "unprognostic (2.45e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.86e-4)" "unprognostic (6.94e-2)" "unprognostic (2.69e-1)" "unprognostic (1.94e-2)" "unprognostic (3.27e-2)" "unprognostic (1.61e-1)" "unprognostic (1.16e-2)" "unprognostic (3.18e-3)" "unprognostic (7.21e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" "unprognostic (4.57e-2)" "unprognostic (5.72e-3)" 60.9 12.6 7.7 16.9 8.0 35.0 53.6 8.0 10.9 24.9 12.7 25.3 18.5 19.7 2.2 86.0 21.7 8.9 32.7 8.0 9.8 19.5 63.5 25.0 10.3 9.8 8.5 22.2 188.9 7.8 9.2 28.6 9.8 19.2 15.4 1.5 164.2 17.0 98.1 20.8 23.1 14.4 8.5 23.9 43.8 5.5 10.1 9.6 9.6 27.2 10.4 33.6 26.5 10.8 146.9 113.2 32.4 193.2 41.3 32.3 77.0 130.5 111.9 128.4 203.5 74.8 56.3 46.3 101.5 121.3 77.1 85.1 109.1 197.5 74.8 36.0 190.9 269.6 52.0 104.9 423.6 98.8 60.4 100.0 314.9 142.0 264.1 40.1 208.2 57.7 152.7 221.8 54.8 141.7 95.9 297.8 186.0 112.9 243.7 80.3 80.4 197.4 49.3 22.3 281.6 200.8 26.1 78.8 534.8 20.3 105.8 192.2 105.2 76.1 167.1 179.9 137.8 185.1 121.6 72.1 173.4 213.4 169.1 51.1 416.3 258.3 27.9 336.6 27.3 130.7 32.8 30.9 335.0 103.3 26.2 26.0 39.4 35.0 268.3 242.6 66.0 258.3 7.7 8.0 8.0 10.9 8.0 9.8 9.8 8.5 9.8 8.5 10.1 10.8 23.6 9.6 8.3 1.6 25.2 74.4 42.4 114.8 51.8 3.6 84.8 72.8 41.7 57.2 97.3 20.2 2.1 41.3 27.3 70.1 29.4 226.1 17.0 11.6 39.0 54.6 40.2 79.9 0.8 730.0 224.2 68.6 35.7 12.5 18.4 76.0 65.3 103.4 223.4 0.0 1.3 138.2 79.3 108.6 82.2 106.2 43.5 83.9 72.9 1.9 101.9 19.2 21.6 4.0 0.4 277.9 64.5 19.2 38.7 100.2 19.5 103.1 33.5 2.2 13.1 17.6 85.2 1.9 25.5 209.3 85.4 38.6 19.8 69.3 83.8 58.9 EIF4G1 "EIF4F, EIF4G, p220, PARK18" ENSG00000114867 "Eukaryotic translation initiation factor 4 gamma 1" Q04637 3 184314495-184335358 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding, Translational shunt" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 348.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014774, HPA028487, HPA043866" Approved Enhanced Cytosol NA NA 330000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB014774: , HPA028487: AB_10602219, HPA043866: AB_2678705" "unprognostic (4.14e-3)" "unprognostic (2.10e-2)" "unprognostic (6.01e-2)" "unprognostic (3.01e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (4.27e-3)" "unprognostic (2.35e-1)" "unprognostic (1.54e-1)" "unprognostic (1.55e-3)" "unprognostic (7.06e-3)" "unprognostic (2.42e-1)" "unprognostic (7.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.33e-3)" 86.2 91.8 24.8 75.7 22.2 84.0 69.0 17.9 22.2 66.6 34.1 81.8 62.0 71.3 32.7 126.8 59.6 50.9 90.8 23.3 29.8 53.9 113.0 74.2 55.7 38.5 36.1 57.5 96.2 99.3 57.4 59.4 32.4 62.2 56.5 22.3 93.1 59.2 348.3 116.7 67.2 74.7 24.4 58.2 79.9 64.8 37.4 49.1 71.3 177.0 63.2 76.0 85.3 16.6 559.0 232.3 173.1 205.7 196.9 192.5 322.5 298.6 204.1 315.4 238.8 486.5 173.7 348.4 381.9 367.6 358.5 292.7 322.6 365.8 230.5 375.1 345.8 321.3 226.1 206.4 173.4 321.4 212.2 199.6 206.8 292.4 268.8 152.8 278.3 128.8 239.6 267.2 205.7 403.4 219.7 105.3 368.9 241.3 180.8 221.7 183.4 281.9 156.8 331.8 197.7 174.6 258.1 415.6 187.6 144.6 445.2 206.5 364.1 227.2 228.9 297.3 567.9 203.8 263.2 629.0 260.5 271.4 258.3 8.3 16.0 6.7 11.7 14.4 10.8 7.7 7.8 9.6 12.8 9.2 6.9 7.6 5.6 8.7 21.0 18.1 6.0 12.7 24.8 22.2 17.9 22.2 23.3 29.8 38.5 36.1 32.4 24.4 37.4 16.6 63.9 76.9 72.6 23.8 41.7 59.1 78.2 58.0 70.6 24.2 69.3 46.2 109.4 50.1 72.3 62.5 14.6 64.0 37.6 135.5 13.7 98.8 151.6 53.0 67.1 69.3 55.7 82.7 10.8 135.3 74.8 64.5 75.4 85.6 48.0 163.8 43.5 152.8 66.8 21.9 12.9 97.2 50.8 40.8 39.9 202.7 73.0 48.9 33.8 14.0 53.0 23.2 30.9 4.0 10.1 149.0 69.0 56.1 112.9 96.8 77.0 45.4 51.4 23.2 78.9 81.6 78.9 24.8 41.4 120.7 91.8 79.6 46.0 94.8 108.4 95.6 EIF4H "KIAA0038, WBSCR1, WSCR1" ENSG00000106682 "Eukaryotic translation initiation factor 4H" Q15056 7 74174231-74197122 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 990.0;Late spermatids: 2765.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030542 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 750000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nuclear bodies" "HPA030542: AB_10601368" "unprognostic (2.83e-1)" "unprognostic (9.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (3.89e-4)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.61e-2)" "unprognostic (2.72e-3)" "unprognostic (1.79e-1)" "unprognostic (2.99e-2)" "unprognostic (1.72e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-2)" "unprognostic (3.04e-1)" "unprognostic (2.23e-1)" "unprognostic (5.68e-2)" "unprognostic (1.27e-2)" 186.9 174.9 151.0 117.8 159.3 283.3 168.3 163.8 157.3 179.8 129.6 208.4 130.2 186.4 76.6 249.3 163.6 100.0 171.0 149.9 151.9 156.6 197.0 158.4 130.3 161.9 156.9 181.2 226.4 160.7 119.9 162.8 162.2 150.3 100.2 149.8 170.1 125.1 399.8 230.9 148.9 119.2 165.2 137.4 192.9 79.9 164.6 150.2 141.2 173.4 137.2 175.3 179.7 187.1 526.3 341.4 251.3 303.1 220.8 231.8 283.4 359.8 276.3 300.3 289.5 423.3 388.6 444.3 96.6 338.8 424.2 266.6 280.5 481.5 286.3 298.0 329.2 247.5 305.2 345.9 253.1 429.0 236.9 273.2 300.8 326.2 460.7 341.5 326.8 260.1 445.8 186.4 305.2 448.2 342.0 516.8 337.6 430.3 328.9 386.9 342.7 401.5 250.9 324.7 252.7 325.4 340.9 420.3 296.0 331.3 476.8 272.4 340.2 411.6 284.6 345.1 474.4 218.8 299.8 771.4 326.3 435.1 441.4 213.7 229.7 245.6 156.9 255.6 164.5 146.4 161.4 158.3 224.2 132.9 183.9 151.7 150.1 193.5 270.2 95.1 194.7 388.0 151.0 159.3 163.8 157.3 149.9 151.9 161.9 156.9 162.2 165.2 164.6 187.1 105.8 83.3 81.2 15.7 97.1 119.2 153.8 101.5 78.0 93.1 103.0 95.5 43.3 68.6 68.7 44.1 25.0 198.8 91.9 98.7 107.6 148.1 990.0 104.8 98.3 103.0 90.4 79.5 25.3 157.7 381.4 101.6 61.2 112.5 122.4 112.1 79.6 95.7 124.2 97.6 24.6 87.2 91.6 101.2 102.7 2765.8 103.8 86.8 72.9 15.9 157.4 134.7 119.4 16.6 44.2 147.0 82.8 110.6 82.7 140.7 84.6 69.0 57.8 72.3 85.5 107.3 117.7 61.2 64.6 90.1 116.1 395.3 92.4 116.9 109.5 140.4 EIF5A "EIF-5A, EIF5A1, MGC104255, MGC99547" ENSG00000132507 "Eukaryotic translation initiation factor 5A" P63241 17 7306999-7312463 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005042, HPA061298, HPA074052" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Plasma membrane" "CAB005042: AB_562281, HPA061298: AB_2684472, HPA074052: " "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (8.10e-2)" "unprognostic (2.80e-1)" "unprognostic (6.95e-2)" "unprognostic (1.39e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (9.04e-4)" "unprognostic (4.10e-1)" "unprognostic (4.11e-2)" "unprognostic (1.64e-2)" "unprognostic (8.25e-2)" "prognostic unfavorable (1.63e-5)" "unprognostic (3.53e-1)" "unprognostic (2.79e-1)" "unprognostic (6.01e-2)" "unprognostic (7.65e-2)" 317.2 309.3 82.3 138.3 83.8 221.5 240.7 85.5 99.0 222.7 77.8 247.5 113.0 206.2 85.8 575.9 188.1 73.7 316.1 87.8 89.8 241.7 495.6 244.5 135.0 87.7 86.4 161.2 295.0 79.7 166.7 96.4 93.0 189.1 125.7 47.6 230.9 65.6 572.1 407.8 207.5 106.1 86.5 227.4 226.7 201.7 92.3 122.5 181.6 160.3 154.4 221.3 281.8 88.6 838.2 958.6 275.8 570.6 220.8 270.2 427.1 546.2 360.7 730.1 501.6 583.6 343.3 749.7 350.9 451.4 300.3 572.3 610.0 777.8 665.9 466.2 987.2 477.9 710.1 750.6 388.6 324.0 431.7 302.5 374.9 587.8 736.0 259.1 501.4 232.0 673.8 192.2 527.3 496.2 388.6 523.3 525.8 477.2 498.0 412.0 320.5 732.4 464.6 393.8 340.5 431.8 330.0 469.4 360.8 212.3 327.2 258.4 427.7 567.6 379.5 326.2 896.4 168.8 229.9 443.6 515.1 527.2 642.2 146.8 137.6 102.0 157.4 193.1 187.5 154.5 153.1 137.2 215.9 149.1 139.6 144.6 62.0 195.1 186.5 225.0 156.7 200.3 82.3 83.8 85.5 99.0 87.8 89.8 87.7 86.4 93.0 86.5 92.3 88.6 180.1 54.5 37.9 6.2 241.9 349.0 67.9 226.5 378.5 88.3 258.8 138.7 77.8 125.8 72.7 62.5 14.6 324.3 200.3 316.0 74.3 317.3 153.8 136.4 255.2 176.6 150.6 456.1 6.8 239.8 633.8 199.6 172.8 187.8 138.4 87.3 105.7 236.4 296.8 50.5 7.0 317.4 83.4 133.6 283.1 112.9 100.6 151.9 263.3 4.7 245.0 122.2 216.3 2.0 11.5 322.0 223.7 81.3 386.7 507.1 229.3 127.1 41.3 65.0 92.1 160.7 262.1 200.4 82.6 572.0 313.7 428.4 179.3 290.7 384.7 207.0 ELANE "ELA2, HLE, HNE, NE" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "bone marrow: 3894.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.7;Fibroblasts: 16.2;Langerhans cells: 11.1;Leydig cells: 6.2;Melanocytes: 7.2;Suprabasal keratinocytes: 7.4" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 4.0;neutrophil: 12.1" "Group enriched" "Detected in many" 9 "granulocytes: 12.1;monocytes: 4.0" "Cell line enriched" "Detected in some" 91 "THP-1: 3105.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015409, HPA066836, HPA073774" Enhanced "Secreted to blood" NA NA 370000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015409: AB_831596, HPA066836: AB_2685733, HPA073774: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" 3.4 1.0 0.3 0.0 0.3 3894.9 3.4 0.1 0.7 0.5 0.2 2.0 0.4 1.0 0.0 1.1 1.4 0.1 4.0 0.3 0.2 0.7 3.3 19.4 0.6 0.1 0.2 0.5 0.5 0.0 1.2 0.8 0.1 2.9 0.0 0.0 2.4 0.1 1.5 5.4 1.8 0.1 0.1 42.6 1.4 0.4 0.2 6.3 3.1 0.0 0.0 2.1 1.0 0.2 2.0 0.1 0.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 3105.0 0.0 0.0 0.1 0.0 1.3 0.0 0.2 0.8 0.0 34.0 0.0 0.0 4.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 27.2 0.3 0.3 0.1 0.7 0.3 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.9 0.0 0.0 0.0 0.3 8.7 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.7 0.0 4.2 0.1 0.0 1.3 16.2 0.0 0.1 0.0 0.0 0.7 0.9 0.2 0.0 0.1 0.0 0.0 3.4 11.1 0.0 6.2 1.1 7.2 0.0 0.9 0.0 1.0 0.0 0.1 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.2 0.0 0.0 7.4 0.0 0.7 0.2 0.0 0.0 ELF3 "EPR-1, ERT, ESE-1, ESX" ENSG00000163435 "E74 like ETS transcription factor 3" P78545 1 202007945-202017183 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Inflammatory response, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 237.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1599.6;Gastric mucus-secreting cells: 1390.9;Paneth cells: 1506.1;Proximal enterocytes: 1476.3;Urothelial cells: 1628.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 209.6;CAPAN-2: 296.0;OE19: 196.3;RT4: 215.3;SK-BR-3: 405.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003316, HPA003479" Enhanced Enhanced Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA003316: AB_1078757, HPA003479: AB_1078756" "unprognostic (9.90e-3)" "unprognostic (1.72e-1)" "unprognostic (7.50e-2)" "unprognostic (1.12e-1)" "unprognostic (2.96e-3)" "unprognostic (3.88e-2)" "unprognostic (1.38e-2)" "unprognostic (1.83e-1)" "unprognostic (1.69e-1)" "unprognostic (5.05e-3)" "unprognostic (7.67e-3)" "unprognostic (7.07e-2)" "unprognostic (9.92e-3)" "unprognostic (4.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.85e-1)" "unprognostic (3.37e-3)" 1.6 0.2 0.2 12.7 0.1 0.8 79.2 0.8 0.4 55.3 0.1 161.3 142.9 12.9 4.5 237.0 35.5 77.6 5.0 0.1 0.2 66.7 79.2 59.8 0.3 0.0 0.0 1.2 120.7 8.4 3.9 6.1 0.1 58.7 127.5 1.0 147.1 14.8 0.2 14.5 145.6 7.3 0.0 0.5 122.7 0.2 0.1 1.6 6.6 0.0 16.0 165.2 93.6 0.2 56.1 209.6 0.0 0.4 0.0 0.0 63.5 0.0 7.9 0.0 0.1 47.3 296.0 0.3 24.0 0.0 1.7 53.8 0.0 0.2 0.0 6.7 0.2 0.0 38.3 9.2 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 40.7 0.3 0.7 3.3 196.3 17.6 0.1 0.1 3.0 78.3 215.3 0.3 0.4 2.4 405.7 0.2 9.2 28.8 0.0 0.1 0.0 0.7 0.4 0.5 1.2 3.9 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.4 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 2.7 294.9 422.9 0.0 12.2 5.1 691.3 879.7 113.8 1.5 470.3 180.3 1.5 586.2 1130.0 329.2 18.8 76.6 9.5 1599.6 41.1 792.7 0.0 812.3 90.8 16.4 452.2 2.7 0.4 641.0 122.2 15.9 1390.9 1127.5 40.6 0.2 0.4 38.6 9.3 0.0 0.2 1225.3 1102.7 2.5 2.7 0.0 0.0 18.6 8.8 0.0 15.4 2.6 1.0 0.5 0.1 512.5 1506.1 0.0 6.0 1014.2 1476.3 147.1 888.2 67.3 0.0 0.8 46.3 0.0 0.3 418.5 8.4 257.2 18.7 0.3 983.0 1628.9 ELF4 "ELFR, MEF" ENSG00000102034 "E74 like ETS transcription factor 4" Q99607 X 130063955-130110716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 34.3;Granulosa cells: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058595, HPA060277" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" Nucleoplasm "HPA058595: AB_2683768, HPA060277: AB_2684239" "unprognostic (1.33e-1)" "unprognostic (8.51e-2)" "unprognostic (3.83e-1)" "unprognostic (2.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (4.43e-3)" "unprognostic (7.86e-3)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.29e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (6.49e-6)" "unprognostic (1.43e-1)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "prognostic favorable (1.42e-4)" 12.2 3.7 1.8 14.6 1.6 53.1 9.6 2.8 2.0 9.4 2.6 18.1 14.2 10.6 2.0 11.7 12.1 9.3 5.6 1.8 2.4 6.0 2.8 15.9 18.3 2.8 2.4 17.5 2.6 4.8 4.2 23.7 2.4 6.1 17.7 0.6 5.5 4.1 2.0 10.9 17.0 10.6 1.5 18.1 20.3 2.6 2.9 19.6 3.9 3.6 18.0 18.8 9.1 3.1 56.0 20.7 3.7 0.4 9.1 19.3 52.6 25.3 32.1 30.4 33.4 28.7 38.9 28.6 49.5 34.8 42.3 35.2 20.5 30.0 29.9 31.0 16.8 56.7 27.3 13.6 20.2 49.7 69.3 20.4 32.6 49.1 48.0 19.0 30.0 6.5 22.0 7.7 16.5 32.8 8.2 28.2 2.4 28.4 19.4 17.6 6.5 12.2 18.3 63.9 13.6 6.0 22.8 21.9 6.9 19.1 11.0 46.9 27.6 21.2 16.6 39.5 47.7 4.2 1.8 22.6 24.6 44.8 5.0 1.6 4.0 5.8 7.1 7.6 5.6 2.6 4.2 6.1 4.5 2.7 4.2 4.8 6.9 6.5 5.5 2.7 4.8 4.2 1.8 1.6 2.8 2.0 1.8 2.4 2.8 2.4 2.4 1.5 2.9 3.1 10.7 9.6 4.4 0.0 8.0 13.6 8.2 2.9 9.1 0.0 2.1 1.5 0.8 0.0 4.4 0.0 0.0 10.6 12.2 24.1 0.0 2.3 0.1 8.9 3.8 8.4 9.0 7.4 0.2 4.0 34.3 6.4 17.9 17.1 1.3 27.5 6.4 1.0 9.7 0.0 0.3 8.3 2.0 12.2 9.2 0.6 1.8 14.8 3.6 5.6 13.1 0.0 16.5 0.0 1.2 9.1 17.4 1.2 2.0 7.5 11.6 0.3 5.4 0.0 6.6 2.6 2.5 0.0 4.0 6.5 10.4 11.2 9.5 5.2 7.1 18.9 ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 170.7;Endothelial cells: 148.0;Hepatic stellate cells: 160.6;Respiratory ciliated cells: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA001600: AB_1078752" "unprognostic (3.11e-1)" "unprognostic (8.81e-3)" "unprognostic (6.38e-2)" "unprognostic (5.77e-2)" "unprognostic (7.18e-3)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-3)" "unprognostic (7.39e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-3)" "unprognostic (2.90e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.05e-2)" 37.1 14.4 5.4 34.2 6.1 18.4 28.4 14.4 5.8 28.0 11.7 15.6 9.2 35.2 9.3 38.1 16.9 30.2 23.9 4.7 7.2 14.0 10.8 27.5 38.0 9.1 7.9 10.2 9.0 11.6 5.8 27.0 7.9 13.1 13.9 2.9 15.3 15.3 11.2 12.5 13.5 37.9 7.0 41.8 14.8 8.6 8.3 19.7 21.8 22.2 37.5 29.2 24.5 6.6 50.3 29.5 29.7 15.8 73.7 137.3 7.6 62.3 118.5 48.6 37.3 1.7 36.6 8.0 20.9 70.4 36.4 17.6 3.3 99.8 85.0 21.7 11.4 2.5 12.2 11.2 22.3 24.2 5.7 81.3 18.4 100.4 75.4 98.5 117.8 6.0 6.0 32.3 166.4 7.6 4.8 16.4 36.3 7.1 38.8 39.7 49.8 9.1 41.7 13.0 1.4 31.4 20.5 9.1 32.0 44.7 5.0 13.3 73.2 132.4 52.2 82.5 54.8 61.7 55.0 1.8 47.0 28.2 94.1 7.1 23.5 0.5 11.1 13.0 42.5 23.2 25.7 15.0 17.7 19.0 15.4 11.4 7.4 20.1 12.1 7.1 45.4 12.8 5.4 6.1 14.4 5.8 4.7 7.2 9.1 7.9 7.9 7.0 8.3 6.6 170.7 6.4 22.3 3.9 22.3 32.6 44.6 15.0 10.8 0.7 7.1 8.1 6.6 2.8 39.4 5.5 4.2 1.2 27.5 2.1 5.9 21.8 1.0 49.0 19.7 148.0 1.2 12.4 4.2 15.6 3.9 35.2 3.1 44.0 17.1 1.3 160.6 4.3 24.5 0.0 1.9 3.4 2.0 32.0 39.7 2.5 11.5 31.4 12.4 39.4 23.6 5.8 9.2 5.5 5.3 56.8 3.4 10.5 29.5 45.7 0.5 0.7 103.1 0.6 13.1 27.7 19.9 0.2 12.6 24.4 27.0 1.1 32.6 10.6 3.0 79.0 ELK4 SAP1 ENSG00000158711 "ETS transcription factor ELK4" P28324 1 205597556-205632011 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 104.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028863 Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA028863: AB_10602492" "unprognostic (2.08e-1)" "unprognostic (2.71e-2)" "unprognostic (1.98e-1)" "unprognostic (1.59e-1)" "unprognostic (2.15e-1)" "prognostic favorable (4.65e-4)" "unprognostic (2.97e-1)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.27e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.94e-6)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.08e-1)" "unprognostic (5.58e-3)" 9.0 4.9 7.4 11.5 11.0 11.7 8.1 12.2 7.5 8.2 7.0 6.9 6.1 7.7 7.2 8.0 6.7 9.2 7.0 6.0 6.4 7.8 13.2 9.7 17.5 8.5 8.8 6.7 8.1 7.8 5.5 7.9 9.9 26.0 6.8 9.3 8.2 5.7 10.6 13.5 9.6 6.1 9.1 15.8 7.7 7.3 8.5 14.1 6.9 8.7 16.8 9.6 9.3 14.1 14.9 13.2 5.1 13.3 11.9 15.2 12.9 9.8 10.1 7.6 8.9 5.7 14.6 31.3 9.0 12.2 5.7 18.0 10.9 12.0 13.1 35.9 7.7 13.6 22.0 12.2 16.1 25.7 51.8 13.4 14.5 12.0 24.4 14.7 32.3 14.8 12.7 25.6 10.7 20.1 21.3 9.5 8.5 3.4 7.8 15.7 31.2 25.4 10.2 32.0 5.9 7.0 25.2 13.7 17.3 8.9 12.7 8.5 23.5 15.3 17.8 13.7 18.8 19.1 18.9 21.1 13.3 10.3 18.2 6.6 0.4 0.7 0.8 0.5 1.1 0.7 0.9 1.1 0.6 1.1 1.1 1.6 0.2 0.6 0.3 0.8 1.0 0.4 7.4 11.0 12.2 7.5 6.0 6.4 8.5 8.8 9.9 9.1 8.5 14.1 50.7 9.6 16.2 7.2 39.3 39.4 35.3 19.0 9.6 104.8 15.1 11.9 20.8 34.3 17.8 31.3 12.5 15.6 34.0 13.8 3.9 14.7 17.4 37.7 37.4 40.1 13.1 21.4 22.8 17.8 6.2 23.2 18.3 82.5 28.5 12.8 36.4 30.2 10.0 25.2 11.7 18.3 14.2 23.5 39.1 19.5 25.4 22.3 30.2 27.2 22.3 11.2 39.1 17.6 28.0 17.5 9.0 15.4 18.6 71.3 14.4 17.5 24.9 26.9 26.3 28.5 21.4 24.6 11.6 19.2 48.6 18.3 32.6 16.7 17.5 103.1 ELL "C19orf17, ELL1, Men, PPP1R68" ENSG00000105656 "Elongation factor for RNA polymerase II" P55199 19 18442663-18522116 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 297.2;Late spermatids: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004202, HPA046076" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA004202: , HPA046076: AB_2679526" "unprognostic (9.49e-2)" "unprognostic (1.38e-1)" "unprognostic (3.26e-3)" "unprognostic (2.07e-1)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (8.26e-2)" "unprognostic (2.71e-1)" "unprognostic (2.34e-1)" "unprognostic (3.00e-2)" "unprognostic (6.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.57e-1)" "unprognostic (2.07e-1)" "unprognostic (5.12e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" 15.1 7.7 4.0 9.0 6.2 29.8 11.8 8.4 7.0 11.2 5.0 10.6 6.5 11.0 2.0 10.3 10.6 5.7 10.5 3.6 4.2 12.6 14.1 16.6 7.6 4.7 4.2 13.0 10.0 4.1 11.3 10.0 3.8 9.9 2.3 1.2 8.3 3.6 20.1 15.3 12.8 3.6 4.0 17.3 10.1 38.5 6.1 6.8 8.2 9.9 4.3 10.5 11.0 3.9 12.7 5.7 3.2 6.8 3.4 4.2 22.7 10.0 8.8 7.5 7.1 7.1 9.8 15.6 11.8 6.7 5.2 8.6 4.7 11.1 3.8 13.3 10.9 9.4 5.9 6.3 5.2 10.3 11.8 8.6 9.3 9.8 7.7 5.6 5.4 8.5 13.5 21.8 4.0 10.3 12.5 11.9 10.6 7.8 16.8 10.9 4.8 17.4 5.3 8.8 5.7 6.4 7.4 12.3 11.0 4.1 6.4 12.4 9.0 8.6 6.6 11.6 9.3 34.8 23.4 11.7 11.4 17.6 12.5 0.3 5.9 4.5 4.5 4.1 7.3 2.9 2.6 3.9 5.0 2.1 1.7 2.7 18.1 2.3 2.1 8.6 3.1 4.1 4.0 6.2 8.4 7.0 3.6 4.2 4.7 4.2 3.8 4.0 6.1 3.9 12.3 6.4 6.1 9.1 16.3 28.0 26.4 11.9 23.3 4.5 19.7 10.7 5.1 11.5 7.2 3.7 4.2 47.5 29.5 15.2 11.7 8.7 297.2 22.9 16.0 11.4 19.7 10.3 9.1 8.0 17.6 17.2 12.8 37.7 11.4 5.1 7.5 15.5 19.3 1.7 11.2 10.1 6.1 12.8 21.7 235.9 6.5 20.4 7.2 9.4 13.8 5.3 4.1 7.1 8.0 10.8 3.7 3.0 53.6 14.2 11.8 7.0 8.4 3.4 19.7 13.0 16.7 18.2 24.7 19.4 30.4 68.7 19.2 5.9 7.1 19.9 EML4 "C2orf2, ELP120, ROPP120" ENSG00000143924 "EMAP like 4" Q9HC35 2 42169353-42332548 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 186.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036687, HPA036688, HPA065337" Enhanced Supported Microtubules,Cytosol NA NA 25000 "Cluster 13: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Microtubules Cytosol "HPA036687: AB_2675251, HPA036688: AB_10671968, HPA065337: AB_2685474" "unprognostic (1.70e-1)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "unprognostic (3.53e-3)" "unprognostic (1.79e-2)" "unprognostic (9.19e-2)" "unprognostic (8.61e-3)" "unprognostic (1.61e-2)" "unprognostic (2.96e-3)" "unprognostic (6.80e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (1.86e-2)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" 11.2 13.7 1.5 32.4 2.5 41.1 14.1 1.0 1.4 11.7 3.9 23.6 38.8 11.1 4.6 11.1 9.9 19.9 4.6 1.6 1.0 19.4 38.1 24.3 28.3 2.2 1.6 8.9 24.3 13.8 4.3 35.6 1.6 9.7 23.7 10.3 21.0 8.0 2.4 18.3 36.5 14.1 2.0 28.3 20.9 20.4 3.7 14.9 21.5 3.9 30.0 27.3 5.7 2.8 45.1 76.7 43.7 34.9 15.6 25.4 47.7 27.3 21.4 29.7 28.5 80.8 55.1 41.1 18.5 26.9 45.6 22.7 38.0 26.3 51.3 80.8 31.8 37.7 23.5 186.3 19.7 28.8 37.1 27.9 9.8 39.4 26.5 14.4 20.9 14.0 37.9 40.3 32.5 26.4 27.3 7.7 44.8 57.8 21.9 27.8 69.2 24.3 24.2 64.3 42.9 86.3 26.9 27.7 20.8 39.6 14.4 11.4 24.6 30.1 39.9 24.3 24.9 44.9 33.3 34.6 26.3 27.0 21.6 5.6 4.7 9.9 9.0 13.7 19.0 13.9 15.0 14.8 4.1 9.1 12.8 9.6 12.3 11.9 14.6 5.3 22.3 7.6 1.5 2.5 1.0 1.4 1.6 1.0 2.2 1.6 1.6 2.0 3.7 2.8 47.0 60.9 107.3 37.9 137.6 67.3 74.3 60.5 75.1 35.1 53.5 45.7 7.0 51.5 60.9 40.5 47.9 143.0 120.8 57.0 17.6 34.0 33.1 33.4 50.1 50.8 102.3 20.8 54.2 75.4 47.5 55.3 76.0 86.6 48.1 80.7 43.9 61.9 65.6 16.8 60.0 69.3 34.6 40.3 56.6 31.0 23.9 74.8 16.0 119.9 38.4 35.1 47.4 62.8 32.9 38.1 58.9 23.0 139.5 65.4 51.3 41.3 28.6 47.3 6.6 25.0 47.6 46.5 39.4 73.4 79.7 118.9 223.8 42.0 85.0 96.4 ENC1 "ENC-1, KLHL37, NRPB, PIG10, TP53I10" ENSG00000171617 "Ectodermal-neural cortex 1" O14682 5 74627406-74641424 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 197.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 271.6;Theca cells: 210.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 51 "amygdala: 61.3;basal ganglia: 114.2;cerebral cortex: 190.0;hippocampal formation: 197.3;white matter: 68.6" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 263.2" HPA078061 Uncertain "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA078061: " "prognostic unfavorable (3.88e-4)" "unprognostic (4.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.00e-3)" "unprognostic (1.05e-1)" "unprognostic (2.22e-3)" "unprognostic (1.36e-1)" "unprognostic (9.74e-2)" "unprognostic (1.24e-1)" "unprognostic (2.59e-1)" "unprognostic (4.98e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (2.95e-5)" "unprognostic (9.69e-2)" "unprognostic (3.08e-1)" "unprognostic (2.88e-1)" "unprognostic (5.65e-2)" 5.5 2.0 61.3 13.5 114.2 18.0 4.3 0.0 190.0 9.9 0.0 14.7 17.9 6.9 3.8 5.7 2.4 19.2 8.2 197.3 0.0 5.7 18.8 12.7 5.8 0.0 0.0 15.0 32.8 24.7 6.8 11.4 2.4 11.8 21.2 2.3 15.6 19.3 4.7 4.3 21.6 7.6 1.0 11.4 27.0 12.0 0.0 7.1 2.7 3.8 5.0 20.3 3.1 68.6 40.0 47.9 45.8 22.1 20.1 4.5 109.6 27.7 27.6 27.8 19.9 74.0 60.0 0.0 30.9 21.5 46.0 29.9 0.7 46.7 60.0 0.8 3.4 43.6 9.5 36.8 1.9 4.9 0.4 7.6 3.3 72.3 7.3 102.2 23.2 9.5 9.9 23.4 81.5 10.4 4.2 6.4 51.2 39.1 40.4 4.8 31.0 4.0 17.3 27.5 60.3 26.9 4.5 20.5 2.4 58.3 9.7 6.6 59.2 46.3 75.3 30.4 87.7 0.5 0.1 0.8 53.8 4.0 73.9 0.0 2.7 2.6 1.2 2.3 0.0 0.0 0.2 1.4 1.2 0.1 0.1 1.3 0.6 1.4 0.6 0.0 0.0 0.8 61.3 114.2 0.0 190.0 197.3 0.0 0.0 0.0 2.4 1.0 0.0 68.6 10.6 0.0 17.0 18.9 11.7 2.5 14.0 20.2 1.2 1.1 9.1 14.7 2.3 17.2 22.6 11.0 2.1 14.6 51.9 15.3 3.9 69.6 16.2 12.8 7.0 13.9 15.5 0.4 271.6 31.7 5.7 40.4 31.6 11.0 21.5 26.4 41.4 18.0 26.5 0.0 25.4 20.9 57.0 8.2 4.9 20.4 37.6 10.2 0.0 25.3 6.2 0.6 0.0 20.6 15.7 67.0 10.1 33.4 23.2 17.6 12.3 4.4 12.9 1.2 6.6 4.4 41.9 0.5 1.0 3.2 1.1 2.6 15.9 210.4 33.4 18.3 ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 528.7" "Cell type enhanced" "Detected in many" "Adipocytes: 407.5;Endothelial cells: 514.4;Extravillous trophoblasts: 294.4;Hepatic stellate cells: 579.0;Leydig cells: 487.1;Peritubular cells: 1421.8;Syncytiotrophoblasts: 376.4;Theca cells: 308.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.1" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 263.8;HUVEC TERT2: 487.4;TIME: 1027.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" 234.5 92.6 44.4 80.2 41.5 18.8 164.8 45.2 44.5 129.7 50.4 62.4 33.2 111.1 35.1 43.1 122.4 58.7 528.7 36.7 43.1 211.6 60.7 260.7 43.4 50.0 47.1 220.9 47.1 29.7 56.1 93.6 52.8 93.9 17.5 2.1 46.2 73.5 72.3 51.3 76.8 65.7 43.1 226.5 57.6 98.9 59.4 17.3 169.2 54.8 17.7 93.0 95.8 43.6 1.3 1.0 7.1 0.4 117.8 81.0 217.8 147.1 102.0 74.4 43.4 0.5 1.3 1.0 70.2 263.8 56.8 2.4 0.0 23.2 24.5 0.7 0.3 42.3 76.7 4.6 91.7 20.2 0.5 137.6 5.4 97.7 34.9 1.0 487.4 1.4 0.7 1.4 88.1 0.9 0.6 1.8 1.7 0.3 4.2 66.9 12.5 1.4 0.0 0.4 0.8 1.8 78.0 65.3 20.1 4.7 13.8 29.8 1027.5 248.1 13.7 164.7 0.7 5.2 1.2 0.9 67.1 52.0 83.2 0.0 19.9 0.5 1.8 28.2 0.6 0.6 3.0 3.4 10.3 1.4 1.9 3.0 0.5 7.6 22.1 3.8 1.2 8.4 44.4 41.5 45.2 44.5 36.7 43.1 50.0 47.1 52.8 43.1 59.4 43.6 407.5 3.2 16.0 2.0 9.2 12.0 2.3 2.1 2.8 2.8 9.5 9.8 28.4 18.6 2.3 3.7 4.2 30.0 8.6 0.4 0.0 10.2 8.6 7.7 67.9 514.4 2.4 49.2 0.6 1.1 294.4 85.7 3.1 8.1 15.2 0.8 579.0 9.8 132.0 0.0 0.7 1.6 0.0 65.4 29.7 51.4 487.1 56.6 24.9 78.7 36.2 2.0 4.1 1.5 1.1 1.4 0.0 1421.8 2.1 2.0 0.0 0.3 5.1 4.6 72.3 44.0 57.5 4.4 5.2 1.3 8.4 376.4 9.6 308.1 0.5 1.4 ENO1 "ENO1L1, MBP-1, MPB1, PPH" ENSG00000074800 "Enolase 1" P06733 1 8861000-8879190 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Plasminogen activation, Transcription, Transcription regulation" "DNA-binding, Lyase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 2259.3;Extravillous trophoblasts: 2078.5;Muller glia cells: 2624.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018614, HPA068284, HPA068721, CAB069394, CAB080034" Supported Enhanced "Plasma membrane,Cytosol" NA NA 310000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "CAB018614: AB_2099061, CAB069394: , CAB080034: , HPA068284: , HPA068721: AB_2732119" "unprognostic (6.51e-3)" "unprognostic (9.50e-3)" "unprognostic (3.56e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (2.71e-4)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (2.37e-2)" "unprognostic (5.58e-2)" "unprognostic (9.72e-2)" "unprognostic (1.67e-2)" "unprognostic (1.46e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.36e-3)" 463.4 418.4 552.9 553.3 591.7 792.8 409.1 679.7 749.9 370.7 585.6 382.6 401.2 321.7 125.7 1049.4 281.6 302.0 328.2 638.1 599.6 1063.6 612.2 453.2 492.4 624.1 607.7 295.0 220.8 347.2 245.7 362.7 602.9 279.2 358.3 741.5 581.3 354.2 231.0 548.1 382.3 471.3 583.4 394.9 321.6 217.7 585.3 455.6 271.4 146.5 695.4 485.9 519.7 571.5 3637.0 3088.4 1461.8 1258.6 1194.2 1323.8 1316.6 1919.1 2110.9 4044.1 3767.4 1986.9 2041.5 2586.5 2496.8 2328.5 1651.8 1736.8 2511.5 5127.7 4081.0 1780.5 2645.9 2191.3 2848.0 2511.0 1789.6 4421.6 1290.1 1377.4 1526.1 3208.9 4825.9 3045.2 2630.1 1294.6 2444.4 982.3 2664.2 1784.1 1685.2 2354.5 1600.3 1290.4 3063.4 1712.4 2172.9 4259.0 4815.0 843.6 1961.4 1211.1 2251.0 3232.5 2407.8 1748.4 1621.8 1302.1 2424.7 2774.5 2444.5 2402.3 3328.3 2771.0 2120.4 3906.9 4313.8 3556.1 2388.6 195.9 1198.7 232.3 528.4 822.7 597.3 411.2 552.5 543.2 1216.4 386.1 443.4 466.0 230.6 635.3 830.6 336.1 700.0 2171.2 552.9 591.7 679.7 749.9 638.1 599.6 624.1 607.7 602.9 583.4 585.3 571.5 140.0 278.9 499.1 99.6 222.3 416.5 570.9 1939.8 348.8 178.2 242.7 324.6 69.6 283.1 657.4 606.9 70.9 1045.4 194.0 455.9 925.4 2259.3 281.3 205.3 227.7 314.3 189.0 145.4 32.0 1399.1 2078.5 303.5 144.8 248.4 297.2 408.6 133.5 351.7 1147.4 482.9 33.2 297.3 787.3 356.4 524.5 699.6 171.5 454.2 448.2 30.9 1558.2 2624.9 279.1 28.6 26.9 1433.6 366.9 135.1 211.0 555.7 742.2 1005.4 245.7 216.6 151.2 156.1 402.5 215.1 154.3 468.1 349.6 1001.8 285.6 609.8 528.4 444.2 ENO2 ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 1695.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 318.2;Cone photoreceptor cells: 312.8;Horizontal cells: 429.0;Rod photoreceptor cells: 787.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 9.9;MAIT T-cell: 11.3;memory B-cell: 6.8;memory CD4 T-cell: 13.1;memory CD8 T-cell: 11.4;naive B-cell: 4.4;naive CD4 T-cell: 8.2;naive CD8 T-cell: 8.6;neutrophil: 7.0;T-reg: 7.5" "Group enriched" "Detected in many" 7 "B-cells: 6.8;granulocytes: 7.0;T-cells: 13.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 537.4;U-87 MG: 398.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 55000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB000063: AB_2099322, CAB073539: , CAB079023: , HPA068284: , HPA068721: AB_2732119" "unprognostic (8.96e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.28e-1)" "unprognostic (7.95e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (7.89e-11)" "unprognostic (7.61e-2)" "unprognostic (3.06e-1)" "unprognostic (8.10e-3)" "unprognostic (1.24e-1)" 25.6 46.7 280.8 20.0 289.7 9.6 20.2 291.2 400.7 55.9 97.5 74.0 10.2 40.1 12.6 15.3 40.2 17.9 53.7 295.0 289.4 27.8 7.7 33.8 26.3 289.4 189.9 29.7 9.0 43.6 124.4 10.4 282.2 34.9 15.5 1695.6 13.8 34.4 7.4 19.3 37.1 35.0 164.3 26.4 30.4 9.6 259.0 26.7 42.0 6.4 24.4 57.4 44.1 306.2 74.3 45.3 16.2 0.5 23.7 26.0 1.5 56.5 37.3 82.0 125.9 8.6 5.8 103.9 9.5 24.3 108.8 11.0 173.0 15.4 116.1 211.9 16.6 141.0 47.7 60.3 17.4 8.3 161.2 13.0 0.7 61.1 11.5 537.4 17.5 137.9 9.5 1.1 56.3 10.3 66.9 8.8 84.9 31.7 27.2 75.0 13.9 22.9 38.5 9.8 128.3 94.0 14.3 1.0 96.3 76.4 4.5 3.9 20.9 69.4 73.7 95.7 73.0 73.3 79.5 15.4 398.4 0.3 15.2 2.1 0.0 0.2 9.9 0.0 11.3 6.8 13.1 11.4 0.1 4.4 8.2 8.6 7.0 0.4 0.3 1.2 7.5 6.1 280.8 289.7 291.2 400.7 295.0 289.4 289.4 189.9 282.2 164.3 259.0 306.2 3.2 35.3 27.4 54.2 11.2 6.2 2.3 45.2 1.8 318.2 5.2 4.3 16.1 1.5 17.2 12.9 312.8 0.3 7.5 0.3 0.0 17.0 0.5 9.6 2.1 9.9 23.9 7.0 96.2 1.8 1.1 8.3 2.0 2.7 67.2 1.0 5.3 0.2 1.7 429.0 89.4 0.5 18.3 0.6 6.9 0.3 5.6 5.9 12.4 25.3 3.5 146.1 0.0 23.6 31.5 9.3 1.2 9.8 9.2 2.5 0.1 0.2 32.2 787.2 13.1 8.1 20.2 1.5 2.5 1.1 2.3 0.3 17.1 0.3 0.4 2.2 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41092592-41180077 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favorable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 15.7 13.7 6.8 17.7 8.9 65.1 14.2 20.5 10.8 16.0 6.1 16.6 13.6 17.2 13.5 16.3 16.4 14.2 11.5 7.1 9.4 13.1 15.5 14.7 17.6 10.6 7.8 23.9 18.0 23.2 13.4 19.3 7.7 15.0 14.5 17.8 15.0 15.6 20.4 18.9 16.0 16.4 5.3 17.0 14.5 19.6 8.6 27.2 20.2 23.4 17.9 15.4 14.8 11.2 31.6 21.7 35.4 23.0 22.2 23.3 32.3 15.0 21.8 21.0 21.0 27.8 12.0 32.7 12.2 28.4 18.7 24.1 48.1 20.8 23.5 30.5 32.2 24.4 25.4 22.3 26.9 59.3 26.5 24.8 22.2 30.0 27.0 19.3 24.9 18.7 26.3 43.9 18.3 12.5 16.2 18.9 27.5 38.3 15.2 33.7 16.7 21.3 20.3 40.4 11.3 11.9 51.1 26.0 25.6 29.5 17.8 33.9 31.3 20.3 24.8 16.3 20.8 28.5 14.1 47.9 16.3 17.4 21.5 3.6 1.7 1.6 1.6 1.9 1.5 2.2 1.7 1.7 2.1 1.4 1.4 1.1 4.9 2.7 1.0 1.6 1.4 1.2 6.8 8.9 20.5 10.8 7.1 9.4 10.6 7.8 7.7 5.3 8.6 11.2 45.4 67.3 49.2 58.1 53.8 24.6 22.9 11.6 40.9 44.6 35.1 25.8 31.6 38.6 15.8 25.8 35.5 18.4 63.2 37.0 3.9 16.1 15.3 55.1 56.4 36.2 24.7 60.4 71.8 18.7 17.9 32.0 27.5 72.5 25.3 36.1 32.9 29.2 18.4 25.2 73.6 24.2 2.0 60.7 25.7 6.4 28.9 60.5 8.8 45.9 52.0 27.7 40.2 81.4 80.3 25.8 28.9 30.5 51.2 30.8 20.2 10.8 22.8 30.9 26.3 47.6 36.7 22.8 31.2 35.3 25.9 30.2 46.0 36.7 23.7 36.3 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EPHA1 "EPH, EPHT, EPHT1" ENSG00000146904 "EPH receptor A1" P21709 7 143390289-143408856 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 57.2;parathyroid gland: 206.5" "Cell type enhanced" "Detected in many" "Early spermatids: 23.3;Gastric mucus-secreting cells: 13.3;Proximal enterocytes: 13.2;Squamous epithelial cells: 28.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 1.9;naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.9" "Lineage enriched" "Detected in single" 8 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "CACO-2: 17.9;HaCaT: 16.6;HBEC3-KT: 13.5;MCF7: 15.0;NTERA-2: 54.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" CAB026144 Uncertain NA NA 32000000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 5: NTERA-2 - Transcription" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB026144: " "unprognostic (1.54e-2)" "unprognostic (3.04e-2)" "unprognostic (2.07e-1)" "unprognostic (4.58e-3)" "unprognostic (5.82e-3)" "unprognostic (2.45e-2)" "unprognostic (9.56e-2)" "unprognostic (1.81e-2)" "unprognostic (5.09e-1)" "unprognostic (7.59e-3)" "unprognostic (6.54e-2)" "unprognostic (3.24e-3)" "prognostic favorable (1.14e-6)" "unprognostic (3.73e-2)" "unprognostic (3.28e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" 0.1 0.0 0.0 1.3 0.0 0.3 2.2 0.4 0.1 11.2 1.2 3.7 8.4 0.3 1.2 57.2 3.4 1.5 0.0 0.0 0.0 5.8 15.6 2.3 2.0 0.0 0.0 0.0 5.7 206.5 2.5 0.6 0.0 4.0 1.6 0.0 11.0 1.2 0.0 19.7 6.2 0.1 0.0 0.9 4.2 1.9 0.0 3.4 5.4 0.0 3.5 1.9 25.8 0.1 8.7 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 17.9 7.1 0.0 0.1 0.0 0.0 16.6 0.0 13.5 0.0 0.0 0.0 1.8 0.0 1.7 0.0 0.8 0.1 0.0 4.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 15.0 0.0 1.9 54.4 8.8 0.0 0.0 0.0 0.0 1.1 6.7 0.3 0.0 0.0 8.2 0.0 3.2 3.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.2 0.0 3.8 2.9 0.1 0.1 0.0 0.4 0.1 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.2 0.3 0.1 2.0 6.3 6.5 6.8 0.0 3.3 5.0 1.0 2.8 9.9 7.3 0.0 2.0 0.2 4.2 0.0 4.4 23.3 4.0 1.0 0.2 1.2 0.0 0.6 4.3 2.6 0.5 13.3 6.6 0.0 0.0 0.4 8.8 0.4 0.0 0.3 4.7 2.0 0.3 0.3 9.9 0.6 0.3 0.0 1.0 0.0 0.3 0.0 0.5 0.2 6.3 8.8 0.0 0.6 2.0 13.2 1.5 2.1 0.2 0.0 0.4 0.4 0.5 1.9 28.7 3.7 1.0 4.4 0.0 7.6 5.5 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 39.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 317.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.9" "Group enriched" "Detected in many" 6 "cerebral cortex: 23.8;hippocampal formation: 20.9" "Group enriched" "Detected in many" 9 "basophil: 1.6;gdT-cell: 1.7;MAIT T-cell: 1.7;memory B-cell: 1.3;memory CD4 T-cell: 2.5;memory CD8 T-cell: 1.7;naive B-cell: 1.2;naive CD4 T-cell: 1.0;NK-cell: 3.5;T-reg: 1.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 77.0;ASC diff: 33.9;CACO-2: 59.3;U-2197: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 9300000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favorable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.8 1.6 0.0 1.9 3.9 3.7 3.9 0.0 23.8 4.5 39.7 4.6 1.0 6.4 2.8 4.8 4.9 3.1 17.4 20.9 0.0 4.8 0.8 3.6 2.7 0.0 1.5 11.1 1.1 1.9 0.6 1.6 0.0 5.3 4.5 4.2 2.6 6.1 2.7 12.9 2.8 8.0 0.0 3.4 2.3 11.7 3.7 3.8 9.5 4.0 3.2 3.6 3.5 0.0 2.6 2.4 77.0 0.0 33.9 20.9 0.1 18.2 8.3 16.9 6.2 59.3 0.9 0.0 0.1 26.7 0.0 7.0 12.3 0.1 7.0 9.7 6.4 0.0 0.9 0.0 0.9 0.0 1.4 8.5 4.2 5.3 0.1 10.3 14.9 0.0 0.0 0.0 4.4 9.5 0.2 0.0 5.6 5.9 1.7 0.1 8.5 0.0 25.8 4.3 13.2 0.0 6.2 1.3 1.3 6.2 2.9 0.0 0.0 1.7 3.2 38.4 1.0 0.0 0.1 0.0 6.9 0.0 3.6 1.6 0.0 0.0 1.7 0.0 1.7 1.3 2.5 1.7 0.0 1.2 1.0 0.2 0.1 3.5 0.0 0.1 1.2 0.4 0.0 3.9 0.0 23.8 20.9 0.0 0.0 1.5 0.0 0.0 3.7 0.0 36.3 0.0 6.4 51.9 8.2 6.1 0.7 9.7 2.8 9.8 4.3 6.0 31.6 7.2 13.7 9.2 0.0 0.1 12.2 4.7 7.9 0.2 3.9 1.9 5.7 26.3 3.5 0.0 317.9 0.2 0.0 5.1 4.6 5.2 1.3 9.0 20.0 0.4 0.3 1.7 68.8 12.8 8.2 0.0 1.5 5.8 1.2 0.9 7.2 70.3 0.2 7.2 3.1 8.0 7.9 30.9 3.6 8.6 2.1 1.4 0.1 1.7 4.5 3.2 0.0 3.6 10.2 10.0 1.9 4.1 12.5 0.0 5.4 11.3 6.6 2.4 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.6;parathyroid gland: 69.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 138.6;Inhibitory neurons: 172.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 12.0;HEK 293: 35.1;RH-30: 31.7;THP-1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 660000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 0.3 0.0 1.2 0.4 3.4 0.0 1.2 3.4 5.1 1.4 0.0 24.6 1.5 0.9 0.2 0.2 0.5 2.2 3.6 4.9 2.6 5.9 0.0 0.2 0.0 1.2 2.2 1.9 0.1 69.9 1.2 0.4 1.5 9.7 2.5 1.8 5.4 0.9 0.1 0.2 4.4 2.1 0.4 3.9 10.3 0.9 0.6 0.0 0.1 0.1 0.0 8.2 1.8 1.2 0.0 0.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 35.1 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.6 0.0 1.0 5.4 31.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.4 3.4 5.1 4.9 2.6 1.2 2.2 1.5 0.4 0.6 1.2 0.2 0.0 0.0 4.2 0.0 0.4 0.4 0.0 0.6 18.5 3.1 1.8 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 13.1 1.3 1.4 1.8 0.0 0.0 138.6 0.0 0.0 5.9 0.0 3.8 0.0 3.7 0.0 0.0 0.1 11.8 172.0 0.0 0.0 0.0 0.4 3.3 0.9 0.1 0.0 11.2 0.0 0.4 0.0 4.5 8.3 0.1 0.0 0.0 0.0 0.4 0.0 11.8 0.0 1.0 0.0 0.2 0.5 0.2 1.1 0.2 1.0 0.0 0.2 0.9 0.0 0.1 EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563489-22603595 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 27.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.2;Cone photoreceptor cells: 2.1;Early spermatids: 2.8;Horizontal cells: 3.3;Late spermatids: 5.8;Rod photoreceptor cells: 8.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "SCLC-21H: 59.6" "Region enhanced" "Detected in many" "cerebellum: 13.0" "Region enriched" "Detected in many" 4 "cerebellum: 11.7" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" 0.0 3.5 2.7 0.0 2.3 0.0 0.0 1.5 2.3 0.0 27.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 0.0 0.0 0.0 0.0 1.9 3.1 0.0 3.3 0.0 1.5 0.0 2.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 2.3 4.6 0.0 2.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.6 4.8 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.3 1.5 2.3 4.9 5.3 1.9 3.1 2.0 2.3 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.1 0.0 1.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 8.8 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPHB3 "ETK2, Hek2, Tyro6" ENSG00000182580 "EPH receptor B3" P54753 3 184561785-184582408 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Angiogenesis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 38.1;Breast myoepithelial cells: 50.8;Enteroendocrine cells: 71.5;Intestinal goblet cells: 43.3;Squamous epithelial cells: 44.3;Undifferentiated cells: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 28.8;HaCaT: 40.2;OE19: 28.3;SK-BR-3: 30.9;T-47d: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007698, HPA008184, CAB034350" Enhanced NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB034350: AB_2262377, HPA007698: AB_1848205, HPA008184: AB_1848206" "unprognostic (2.94e-2)" "unprognostic (5.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.80e-2)" "unprognostic (1.52e-1)" "unprognostic (9.19e-2)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (8.83e-3)" "unprognostic (3.03e-2)" "unprognostic (9.59e-3)" "unprognostic (2.10e-3)" 1.7 0.7 3.0 3.7 2.7 0.1 10.4 5.8 4.1 22.7 1.0 10.3 6.4 10.1 1.8 30.6 4.0 2.8 1.9 2.9 2.4 5.8 0.9 3.4 0.9 5.7 3.4 8.3 14.9 1.1 2.0 5.7 6.1 10.0 10.9 0.5 31.7 3.5 0.5 51.5 6.3 3.8 2.3 1.0 22.8 0.9 4.0 0.7 0.9 0.4 2.4 4.0 20.9 2.7 6.6 2.3 14.8 1.6 4.5 0.3 28.8 1.1 1.9 2.2 1.2 2.0 0.2 0.0 2.8 6.3 1.0 40.2 5.4 1.9 0.6 0.2 1.1 0.0 0.3 0.0 0.3 0.0 0.2 1.2 13.0 1.8 0.2 0.7 0.0 0.0 0.0 0.0 1.0 17.6 0.0 6.4 1.4 28.3 2.5 1.5 9.0 0.0 0.0 5.8 1.9 2.2 1.2 30.9 1.3 7.8 20.5 0.1 0.0 3.6 5.1 1.8 2.5 0.0 0.0 0.1 0.3 0.0 14.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 5.8 4.1 2.9 2.4 5.7 3.4 6.1 2.3 4.0 2.7 0.9 3.2 2.7 11.1 0.2 24.1 7.6 5.3 17.1 0.9 38.1 50.8 1.8 2.8 4.6 0.0 0.0 10.1 1.1 21.5 1.9 0.5 0.6 3.7 4.0 1.4 71.5 0.0 4.6 1.6 18.7 6.9 27.0 7.5 4.5 2.1 1.8 0.0 23.5 15.2 5.8 43.3 10.2 0.3 9.8 0.4 2.8 2.4 0.0 1.0 0.8 0.1 0.0 5.0 0.3 3.2 7.2 6.0 0.0 6.0 1.7 0.2 1.4 1.0 0.0 4.5 2.9 0.4 0.6 44.3 35.8 16.3 0.8 1.6 55.0 20.7 EPHB4 "HTK, Tyro11" ENSG00000196411 "EPH receptor B4" P54760 7 100802565-100827523 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Angiogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 68.5;Hepatic stellate cells: 113.2;Syncytiotrophoblasts: 206.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0;neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB013537 Uncertain NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB013537: " "prognostic unfavorable (8.56e-4)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.33e-1)" "unprognostic (5.23e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (9.51e-3)" "unprognostic (6.63e-2)" "unprognostic (3.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (8.84e-4)" 26.4 49.8 5.0 8.0 4.3 5.6 32.6 4.6 4.8 45.6 6.8 20.7 8.3 61.5 3.8 24.7 27.1 18.0 26.1 4.1 4.1 28.3 33.3 28.2 5.8 5.5 5.1 36.0 26.8 10.1 6.3 35.5 5.3 28.9 10.2 0.3 24.2 22.4 7.7 35.8 17.5 22.2 5.1 47.9 21.4 12.3 6.3 3.1 17.6 13.3 4.9 17.3 28.1 4.8 37.7 33.1 32.5 94.2 20.4 13.0 94.7 14.1 31.2 22.3 29.0 27.4 28.3 4.8 63.6 15.3 31.3 38.2 14.3 38.3 11.9 6.2 25.6 1.3 19.0 43.2 11.8 0.7 0.9 15.3 56.7 14.2 33.1 24.8 84.0 1.5 71.9 1.8 18.4 66.4 0.7 15.0 54.7 56.3 47.5 51.4 15.6 8.9 28.6 19.9 0.2 27.4 22.0 10.4 22.1 45.1 26.1 6.7 71.3 27.6 42.6 51.3 21.4 0.2 0.8 1.7 4.0 12.0 51.2 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 4.3 0.0 0.1 0.1 0.0 0.7 5.0 4.3 4.6 4.8 4.1 4.1 5.5 5.1 5.3 5.1 6.3 4.8 47.1 9.6 12.6 1.6 1.9 20.5 10.3 13.9 15.9 0.1 22.0 19.7 5.7 7.2 8.5 5.5 0.0 68.5 1.1 9.1 0.0 12.3 28.5 4.8 21.8 51.2 3.0 10.8 0.3 6.6 11.2 6.5 12.8 8.0 1.3 10.7 113.2 22.4 9.0 0.0 0.2 17.4 8.2 4.1 3.4 9.9 8.1 1.3 3.6 1.9 1.5 1.7 0.0 0.0 1.0 20.6 7.6 4.1 1.4 13.3 1.3 4.0 4.2 0.2 6.6 5.7 6.3 1.4 10.2 12.1 17.8 206.5 1.2 2.9 19.9 8.0 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810124-225845563 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1178.6;liver: 1705.1" "Cell type enhanced" "Detected in many" "Granulosa cells: 349.9;Hepatocytes: 757.6;Theca cells: 1042.6" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 1161.8;SiHa: 413.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favorable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 245.8 1178.6 233.5 23.6 252.5 22.7 163.7 239.0 249.3 188.3 345.8 82.0 102.2 108.1 97.6 159.6 153.8 96.5 94.0 221.3 233.7 110.7 1705.1 146.8 39.1 225.3 234.9 329.1 536.1 147.7 105.8 32.9 223.6 113.2 52.5 30.7 143.6 128.1 142.5 71.5 52.8 109.6 210.1 55.7 99.9 74.3 258.4 25.9 171.1 95.6 33.4 135.4 140.4 227.2 32.1 202.3 12.3 108.5 1161.8 120.2 24.3 29.7 49.2 28.1 35.1 38.8 293.6 1.3 128.7 147.3 30.6 38.1 32.7 16.8 12.1 7.8 46.5 21.8 83.5 282.7 129.8 12.9 15.1 109.2 40.0 74.6 6.3 116.5 22.1 13.4 14.5 27.3 50.4 30.3 13.5 31.0 61.6 178.1 79.4 27.8 15.2 92.9 91.1 132.5 98.3 13.0 413.0 192.1 51.3 32.1 131.7 43.5 46.8 41.9 35.4 54.5 59.0 9.1 38.9 4.1 63.5 14.2 59.5 0.0 2.6 0.1 0.2 0.7 0.4 0.1 0.3 0.2 0.6 0.2 0.5 0.3 0.2 0.7 0.3 0.9 0.3 0.8 233.5 252.5 239.0 249.3 221.3 233.7 225.3 234.9 223.6 210.1 258.4 227.2 196.9 0.0 14.0 41.1 5.7 19.6 121.8 244.2 74.0 8.8 29.7 27.4 1.2 102.9 255.5 51.5 29.2 46.6 3.4 34.5 17.6 95.3 10.2 142.9 32.2 82.7 10.8 7.0 3.1 73.0 7.6 175.6 30.5 93.4 5.7 349.9 88.2 757.6 149.1 1.7 5.0 17.5 103.7 30.9 28.7 28.4 311.3 25.8 42.7 23.4 9.6 99.2 0.0 7.1 19.4 45.5 27.2 159.1 9.5 40.4 63.4 128.9 174.3 10.1 223.5 29.3 146.9 4.4 5.1 129.0 17.6 22.8 4.7 1042.6 31.5 108.5 EPO EP ENSG00000130427 Erythropoietin P01588 7 100720468-100723700 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Erythrocyte maturation" Hormone "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 47.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.9;Exocrine glandular cells: 4.2;Extravillous trophoblasts: 14.0;Hepatocytes: 19.5;Pancreatic endocrine cells: 3.7;Syncytiotrophoblasts: 2.9" "Group enriched" "Detected in many" 5 "liver cancer: 2.7;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "BEWO: 1.6;Hep G2: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" CAB010336 Supported "Secreted to blood" NA NA 12300 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB010336: AB_2098408" "unprognostic (2.93e-1)" "unprognostic (1.57e-2)" "unprognostic (1.08e-3)" "unprognostic (7.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.52e-2)" "unprognostic (5.16e-2)" "unprognostic (9.70e-2)" "unprognostic (2.44e-3)" "unprognostic (3.31e-1)" "prognostic unfavorable (2.18e-6)" "unprognostic (4.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (3.34e-1)" 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.3 2.9 0.1 0.1 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.1 0.4 3.1 47.2 0.1 0.0 0.2 0.1 0.2 8.3 0.0 0.0 0.0 0.2 0.5 0.0 0.2 1.4 0.5 0.0 0.4 0.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 4.2 14.0 0.0 0.0 0.0 0.0 0.1 1.4 19.5 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 2.9 0.0 0.0 0.0 0.0 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 EPS15 "AF-1P, MLLT5" ENSG00000085832 "Epidermal growth factor receptor pathway substrate 15" P42566 1 51354263-51519266 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 314.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008451, CAB010164, HPA061431" Approved Enhanced Vesicles,Cytosol "Intracellular and membrane" NA NA 65000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Cytosol" "CAB010164: AB_631445, HPA008451: AB_1848221, HPA061431: AB_2732662" "unprognostic (1.45e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.05e-2)" "unprognostic (7.72e-3)" "unprognostic (3.99e-1)" "unprognostic (1.42e-1)" "unprognostic (4.96e-3)" "unprognostic (9.26e-2)" "unprognostic (4.13e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (5.36e-2)" "unprognostic (8.73e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" 31.9 35.1 40.3 25.5 48.2 20.7 25.6 38.8 55.7 23.9 25.7 19.1 15.8 22.8 17.6 21.0 18.3 26.1 26.5 43.9 39.1 24.5 26.4 26.9 46.0 38.6 44.1 28.8 14.7 29.0 15.5 31.5 40.7 26.7 20.5 23.4 16.7 20.9 47.6 24.2 17.7 24.3 40.1 34.1 21.3 46.9 45.0 27.6 25.3 40.5 45.6 22.8 20.9 57.2 35.4 10.4 22.0 20.8 49.6 49.2 54.5 24.2 37.9 19.4 28.4 14.4 19.2 71.8 24.3 38.1 39.5 32.7 28.7 23.1 29.1 81.8 18.0 64.1 16.9 17.1 46.7 36.9 56.4 40.3 21.0 34.0 45.7 33.5 36.5 25.2 40.4 31.7 29.8 17.5 29.9 19.8 30.2 24.6 16.7 24.1 33.3 15.9 25.5 43.2 15.0 20.9 28.8 50.4 42.1 60.2 20.5 25.7 51.1 18.0 19.1 36.3 20.5 37.6 41.0 47.6 26.6 41.0 16.1 18.8 10.4 12.1 9.4 10.7 14.2 15.6 11.2 14.9 10.8 9.0 6.6 9.6 7.8 10.8 13.0 7.1 19.0 8.7 40.3 48.2 38.8 55.7 43.9 39.1 38.6 44.1 40.7 40.1 45.0 57.2 51.5 35.3 41.0 142.4 78.3 43.0 32.1 16.4 30.1 18.1 28.2 15.6 59.8 24.3 22.7 44.1 31.3 22.8 65.0 28.5 19.6 15.2 27.0 22.1 50.1 43.3 28.8 81.0 77.1 19.0 18.9 52.5 41.3 35.6 24.6 36.0 61.4 37.7 83.4 28.6 60.6 30.7 12.2 80.9 61.9 61.7 65.9 67.0 103.2 110.5 57.6 38.4 27.8 29.7 314.1 23.3 19.8 48.2 78.4 62.1 20.7 28.1 31.9 26.6 39.5 45.1 38.0 74.4 44.5 33.8 51.0 28.5 74.3 28.5 21.4 50.8 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 136.1;Distal enterocytes: 111.0;Proximal enterocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 5.0" "Lineage enriched" "Detected in many" 4 "T-cells: 5.0" "Group enriched" "Detected in many" 41 "OE19: 6565.0;SK-BR-3: 3115.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 980000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavorable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favorable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 13.0 5.4 16.1 12.1 20.5 1.6 56.0 14.3 13.1 37.6 23.3 68.2 63.6 25.2 26.6 102.4 64.2 31.0 57.0 13.3 16.0 73.5 31.1 36.2 4.8 22.4 22.7 23.9 37.6 81.7 17.3 27.0 17.1 55.6 48.5 8.1 68.7 50.5 20.7 91.0 67.3 25.0 18.5 6.9 49.7 11.7 15.4 7.4 56.5 15.0 28.0 40.0 52.9 16.4 38.7 45.7 50.4 31.7 59.3 41.2 67.7 27.2 44.9 58.6 48.9 34.4 102.7 2.9 54.6 62.7 31.5 117.6 2.8 61.2 26.9 5.2 38.6 1.8 36.0 56.3 35.3 0.9 1.0 41.0 56.6 36.2 21.9 56.2 24.4 1.9 6.2 2.4 43.3 59.4 7.1 3.0 90.7 6565.0 11.7 3.9 20.5 5.4 58.9 118.9 9.4 2.6 51.5 3115.9 16.9 62.2 88.1 2.2 2.9 30.2 37.7 37.7 17.6 5.3 3.3 3.6 3.0 0.9 98.5 1.1 0.2 0.4 5.0 0.1 0.3 0.6 0.2 1.4 0.2 0.6 0.5 1.4 1.2 0.4 0.1 0.1 0.2 1.7 16.1 20.5 14.3 13.1 13.3 16.0 22.4 22.7 17.1 18.5 15.4 16.4 3.9 41.7 40.1 12.7 2.2 14.0 19.0 37.1 17.6 4.6 62.7 34.9 20.7 32.9 43.8 136.1 12.5 12.0 5.1 111.0 7.9 30.9 0.3 48.7 13.9 6.1 15.6 1.3 0.9 25.5 84.8 15.7 53.5 61.3 0.0 20.3 11.7 10.7 4.0 6.7 1.0 47.5 42.7 2.2 3.1 1.0 18.3 1.7 10.6 1.0 1.2 24.1 26.8 2.0 1.0 32.5 54.8 23.0 1.1 34.9 121.7 19.5 42.0 5.8 0.0 13.1 12.7 6.8 5.7 43.5 18.9 22.7 2.8 4.4 75.4 31.3 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;fallopian tube: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 0.3 0.4 10.0 0.0 13.3 0.0 5.6 10.5 11.5 2.9 0.0 0.1 0.0 0.2 0.0 0.1 11.2 0.0 3.0 9.9 12.7 5.1 0.0 0.8 0.0 4.9 16.9 0.1 0.6 3.1 2.4 0.1 7.6 0.3 0.0 2.0 4.7 1.2 1.5 0.3 0.0 0.0 4.3 0.0 0.4 3.3 8.0 0.0 1.6 1.7 0.0 0.1 0.1 6.1 0.0 0.0 6.9 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 5.1 0.7 0.0 0.3 0.2 0.0 0.0 0.1 3.8 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 5.6 0.3 3.1 0.2 0.0 0.1 0.1 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.3 10.5 11.5 9.9 12.7 4.9 16.9 7.6 4.3 8.0 6.1 0.4 0.0 12.6 2020.2 0.0 0.6 0.9 1.1 0.6 15.9 45.6 17.0 27.2 0.0 10.2 12.9 0.0 0.0 0.2 0.0 5.9 0.5 6.7 25.4 1.0 1.0 0.0 0.0 62.0 0.5 0.2 1.8 0.0 25.8 0.0 5.4 0.0 0.0 0.1 0.0 6091.7 0.0 2.0 0.0 0.3 2.2 1.8 0.3 3.6 96.5 0.0 9.1 0.0 2369.0 1049.9 0.0 0.0 0.4 0.0 1.6 0.0 0.2 28.1 1.9 6.6 4.1 3.0 1.8 2.6 0.2 1.3 0.0 0.2 0.0 0.0 1.2 ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 292.3;Horizontal cells: 185.1;Inhibitory neurons: 487.0;Microglial cells: 213.6;Oligodendrocyte precursor cells: 230.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" 10.4 9.7 12.2 6.8 14.4 7.3 8.0 38.1 12.8 8.9 8.0 11.8 3.5 9.0 4.8 11.8 8.2 7.5 13.9 15.2 18.5 9.2 6.5 7.3 4.8 13.7 14.8 10.5 7.6 15.4 8.1 11.8 13.7 9.5 6.2 7.0 8.4 12.1 9.4 9.4 5.8 12.9 11.9 5.8 7.2 7.5 17.7 7.9 13.4 9.0 5.3 13.4 9.0 12.6 8.2 20.1 10.3 7.1 27.8 22.2 14.2 25.0 20.0 17.0 15.3 17.7 10.0 12.5 3.4 33.2 16.8 13.3 22.1 19.7 23.1 25.9 11.6 30.3 20.1 9.3 21.1 16.1 6.9 18.7 17.0 30.0 55.6 20.7 22.3 7.9 9.6 23.9 12.9 9.2 5.2 3.5 16.8 8.1 9.7 9.9 38.9 3.8 16.9 14.2 6.3 12.3 38.8 9.3 13.9 37.6 9.3 7.0 39.6 29.6 29.0 21.6 24.0 6.4 13.1 18.1 19.2 9.4 12.9 1.5 3.1 2.3 1.7 1.2 2.4 12.7 2.7 2.7 2.7 5.6 3.8 2.7 2.4 1.4 4.8 3.4 2.8 0.7 12.2 14.4 38.1 12.8 15.2 18.5 13.7 14.8 13.7 11.9 17.7 12.6 36.9 25.6 25.1 155.4 21.2 21.0 25.6 9.4 29.0 39.2 13.2 14.1 56.4 17.2 17.4 20.2 47.9 34.1 12.6 12.7 1.9 20.3 34.3 31.2 43.4 34.6 30.0 7.6 292.3 13.4 18.0 32.3 23.9 53.9 14.5 59.2 24.3 17.3 12.4 185.1 487.0 11.9 2.0 12.6 16.5 35.2 24.8 17.0 14.2 213.6 18.4 34.8 6.2 230.7 171.1 18.5 10.3 30.9 39.1 30.8 6.1 4.1 13.2 33.4 19.7 35.5 33.1 18.5 28.8 33.8 27.4 78.7 15.8 18.7 10.3 29.4 ERCC1 RAD10 ENSG00000012061 "ERCC excision repair 1, endonuclease non-catalytic subunit" P07992 19 45407334-45478828 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cataract" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004390, HPA029773, HPA050182, CAB072859, CAB072860" Supported Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "CAB004390: AB_2278023, CAB072859: AB_2665703, CAB072860: AB_2665704, HPA029773: AB_10602129, HPA050182: AB_2681044" "unprognostic (1.54e-3)" "unprognostic (5.99e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.41e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (9.69e-4)" "unprognostic (2.57e-1)" "unprognostic (5.80e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (9.00e-5)" "unprognostic (6.19e-2)" "unprognostic (1.96e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-1)" 47.0 49.8 34.7 28.0 33.9 31.4 50.7 37.6 42.6 50.5 44.8 45.1 26.2 47.9 40.2 43.1 43.7 30.3 109.1 35.9 37.2 57.8 38.3 40.4 30.0 38.7 35.5 54.2 57.1 48.9 56.9 22.9 37.3 55.2 20.8 23.2 70.6 29.2 84.0 63.3 40.1 33.4 35.4 43.1 42.9 27.8 36.2 24.1 46.9 83.1 30.5 41.5 44.3 36.6 61.1 104.0 84.2 125.8 57.8 108.1 27.3 90.1 119.1 106.4 141.4 12.0 58.8 34.5 24.9 94.2 57.2 45.0 26.0 277.7 65.1 79.1 28.6 57.9 39.3 36.2 120.2 55.9 96.8 81.0 60.3 111.7 99.5 89.0 117.3 40.8 33.8 69.8 167.9 40.3 50.9 44.4 20.9 54.4 42.4 77.7 40.5 46.3 78.5 36.7 36.6 76.2 58.4 47.3 79.6 27.7 55.0 103.7 70.3 97.7 91.4 59.2 93.8 49.5 43.2 39.5 105.3 45.8 296.6 30.7 131.9 26.3 61.3 142.8 41.7 75.8 37.3 48.6 134.7 84.1 29.4 47.4 17.8 60.6 107.9 315.8 49.8 90.2 34.7 33.9 37.6 42.6 35.9 37.2 38.7 35.5 37.3 35.4 36.2 36.6 43.2 22.4 36.3 13.1 53.4 70.9 109.7 82.7 41.5 0.0 73.9 76.8 39.1 37.1 43.9 20.2 0.0 36.1 67.8 26.9 90.1 54.5 27.1 50.4 43.5 37.5 39.6 20.2 32.9 65.9 33.3 62.4 22.4 24.5 50.0 103.4 38.9 29.6 96.2 0.0 21.9 41.2 34.6 61.5 71.7 107.1 79.2 69.6 67.6 17.8 49.0 0.0 38.1 16.6 13.8 85.3 33.5 57.2 49.1 94.9 69.2 73.1 67.5 0.0 46.0 60.5 60.0 37.0 37.1 51.4 52.8 35.6 36.0 98.6 43.2 89.0 ERCC2 "EM9, MAG, MGC102762, MGC126218, MGC126219, XPD" ENSG00000104884 "ERCC excision repair 2, TFIIH core complex helicase subunit" P18074 19 45349837-45370918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromosome partition, DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 34.1;Spermatocytes: 30.5;Theca cells: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005375, HPA038057, HPA069266" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "CAB005375: AB_2100152, HPA038057: AB_2675810, HPA069266: AB_2686104" "unprognostic (1.10e-1)" "unprognostic (5.48e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-3)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (1.06e-1)" "prognostic favorable (3.26e-4)" "unprognostic (3.36e-2)" "unprognostic (2.44e-3)" "unprognostic (1.94e-1)" "unprognostic (5.47e-1)" "unprognostic (8.99e-2)" "unprognostic (3.45e-2)" 6.8 13.0 10.5 6.9 10.3 4.8 6.5 8.4 11.7 7.5 8.4 7.5 4.9 9.7 3.2 6.3 8.0 4.1 7.0 10.8 9.3 7.6 9.0 5.8 5.8 10.6 9.9 7.8 7.7 7.7 9.7 4.5 9.6 6.7 4.0 3.1 7.3 6.7 11.7 7.2 6.6 6.9 8.1 8.1 7.5 13.9 10.1 5.3 8.4 6.3 5.2 7.5 5.9 8.9 28.0 13.3 27.1 38.4 16.3 19.4 15.2 38.8 27.4 50.2 40.2 32.6 18.6 10.0 21.6 39.9 19.1 14.0 19.1 32.9 18.5 24.4 31.8 16.9 26.8 35.4 33.3 27.1 28.4 22.4 5.6 55.8 31.9 28.2 29.1 28.8 41.8 10.9 34.8 14.7 16.1 17.9 12.7 27.2 24.6 30.3 19.4 8.3 14.0 24.9 15.8 17.1 34.2 23.9 13.6 20.6 22.8 35.4 37.9 46.4 25.3 19.9 88.0 24.9 15.8 14.2 13.8 16.4 21.2 0.0 17.2 6.5 9.1 18.0 11.9 9.1 8.9 8.9 21.8 6.5 8.2 8.7 0.5 15.6 14.9 10.4 9.8 12.1 10.5 10.3 8.4 11.7 10.8 9.3 10.6 9.9 9.6 8.1 10.1 8.9 4.2 6.4 3.4 6.2 5.8 6.2 5.5 8.6 4.6 0.0 6.1 4.3 6.7 8.6 8.7 5.5 0.0 10.5 4.1 5.9 13.7 10.7 4.7 3.3 4.5 5.5 7.2 5.5 2.9 8.2 12.1 6.8 6.1 3.8 0.0 34.1 7.9 12.3 11.5 0.0 3.1 8.5 4.1 8.2 4.2 2.8 6.5 6.3 3.6 1.0 4.2 0.0 5.2 5.0 1.4 8.1 3.1 7.9 7.5 4.2 4.1 13.0 7.5 0.0 0.0 3.5 9.9 30.5 13.1 5.1 5.7 4.8 4.7 29.1 8.8 3.2 ERCC3 "BTF2, RAD25, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037153, HPA046077" Approved Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "CAB037153: AB_796181, HPA046077: AB_2679527" "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-3)" "unprognostic (1.05e-1)" "unprognostic (8.85e-2)" "prognostic unfavorable (1.62e-7)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (9.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (4.30e-6)" "unprognostic (3.71e-1)" "unprognostic (8.50e-2)" "unprognostic (5.73e-2)" "unprognostic (3.92e-2)" 24.4 25.9 15.0 14.5 16.0 19.8 24.4 15.1 16.5 32.2 19.6 28.9 9.6 27.0 11.6 22.7 28.9 14.2 23.4 16.6 14.9 22.8 22.2 22.1 21.6 15.7 14.8 29.5 23.8 26.3 33.8 13.6 16.0 27.4 13.8 4.4 23.2 16.8 35.3 27.7 24.3 21.5 15.1 32.6 23.7 29.8 15.6 26.6 25.0 25.6 22.4 27.2 26.4 15.2 45.9 30.8 37.8 40.6 40.6 27.8 46.4 41.3 52.9 65.1 62.5 48.1 32.9 34.5 33.2 37.8 41.7 40.2 57.7 43.3 56.1 54.4 51.4 43.6 35.8 51.0 30.5 38.1 45.4 28.9 39.8 75.7 32.4 41.5 42.4 44.3 43.0 22.1 41.7 45.1 54.8 42.2 55.0 29.2 47.3 44.5 42.7 28.8 36.4 42.2 45.2 49.2 35.3 52.6 55.0 42.4 28.7 43.0 34.1 39.2 45.2 35.8 49.7 39.2 81.5 54.0 34.3 18.0 42.8 8.0 11.5 8.8 18.2 12.0 18.4 13.7 13.1 15.7 16.9 12.7 17.7 12.2 3.5 25.0 9.9 13.6 20.5 15.5 15.0 16.0 15.1 16.5 16.6 14.9 15.7 14.8 16.0 15.1 15.6 15.2 12.2 22.4 14.6 24.8 17.7 7.6 9.5 20.6 21.1 0.0 13.0 11.6 13.0 5.7 25.4 7.3 0.0 18.6 18.9 6.1 1.9 13.7 9.0 22.9 13.9 12.2 6.1 3.8 22.3 14.9 12.2 16.6 18.8 13.1 10.1 17.1 15.4 8.6 14.6 0.0 23.5 10.0 14.2 12.5 7.6 5.1 16.4 10.7 8.8 10.3 12.3 0.0 14.4 18.1 22.4 15.5 7.3 12.8 16.4 7.4 6.3 8.5 45.2 0.0 13.1 17.6 13.3 41.1 31.0 11.3 9.5 14.6 15.7 12.3 10.6 8.5 ERCC4 "FANCQ, RAD1, XPF" ENSG00000175595 "ERCC excision repair 4, endonuclease catalytic subunit" Q92889 16 13920154-13952348 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 18.5" "Cell type enhanced" "Detected in many" "Early spermatids: 140.7;Late spermatids: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000156, HPA045828" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB000156: , HPA045828: AB_2679463" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "unprognostic (2.12e-3)" "unprognostic (9.41e-2)" "unprognostic (3.35e-1)" "unprognostic (1.40e-2)" "unprognostic (1.64e-2)" "unprognostic (2.26e-1)" "unprognostic (3.59e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (8.49e-2)" "unprognostic (5.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (6.30e-2)" "unprognostic (5.88e-4)" 2.7 3.9 4.7 3.3 5.2 2.5 2.8 6.7 5.4 3.3 4.3 1.9 1.7 3.3 2.8 2.9 3.5 3.0 3.6 4.3 4.9 2.9 3.2 2.7 3.3 5.1 4.8 4.3 2.7 3.9 1.6 2.6 4.9 3.6 2.2 4.1 2.8 2.9 18.5 3.0 1.9 3.6 4.4 3.7 2.6 5.5 5.4 4.2 4.4 3.3 2.9 2.6 1.5 6.8 4.7 5.5 5.3 7.5 8.7 8.1 4.0 6.1 6.4 5.4 6.8 2.1 4.5 7.8 8.6 5.4 4.8 5.8 8.0 4.1 8.3 10.7 4.7 3.8 6.7 5.2 7.9 5.2 4.2 6.1 5.7 7.1 6.0 5.3 7.2 4.6 6.1 8.8 7.6 3.9 7.0 3.4 3.9 2.4 3.1 7.8 10.8 9.7 3.3 3.2 4.3 5.1 7.5 6.0 5.8 4.2 7.5 3.9 7.9 7.8 5.7 7.0 5.4 7.9 9.9 5.2 7.6 6.2 8.1 4.9 2.3 2.3 2.6 2.7 2.9 2.5 2.4 2.0 2.3 3.1 2.4 2.6 2.7 3.6 2.4 3.2 2.5 1.1 4.7 5.2 6.7 5.4 4.3 4.9 5.1 4.8 4.9 4.4 5.4 6.8 14.0 19.2 13.5 16.6 11.3 4.8 6.1 18.3 10.2 0.0 10.0 9.5 8.6 14.3 12.7 5.5 0.0 17.3 9.7 3.3 9.8 11.6 140.7 18.6 19.0 13.5 9.6 12.0 20.4 8.4 6.2 13.0 5.1 7.4 1.3 17.8 17.2 17.7 11.7 0.0 21.2 4.8 10.2 13.6 6.5 117.9 14.9 11.4 10.6 8.4 14.4 0.0 17.5 12.1 20.1 9.9 1.7 21.1 14.4 10.2 4.4 13.3 26.1 0.0 26.3 17.3 12.2 49.4 28.9 9.2 5.5 12.3 11.8 18.0 6.0 4.7 ERCC5 "ERCM2, XPGC" ENSG00000134899 "ERCC excision repair 5, endonuclease" P28715 13 102845831-102875995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.7;Gastric mucus-secreting cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA045845, HPA050374" Supported Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA045845: AB_2679471, HPA050374: AB_2681106" "unprognostic (1.28e-3)" "unprognostic (1.32e-3)" "unprognostic (1.86e-2)" "unprognostic (9.28e-3)" "unprognostic (6.19e-2)" "unprognostic (8.73e-2)" "unprognostic (1.23e-1)" "unprognostic (8.72e-2)" "unprognostic (2.52e-1)" "unprognostic (2.55e-1)" "unprognostic (7.77e-3)" "unprognostic (5.76e-3)" "prognostic unfavorable (2.96e-6)" "unprognostic (3.56e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "prognostic favorable (6.82e-4)" 14.1 11.1 7.8 10.9 8.6 16.3 14.5 8.9 11.8 12.2 10.5 14.5 20.1 9.2 13.4 10.7 9.7 10.8 9.8 8.1 8.2 12.6 21.8 12.8 15.2 8.5 8.2 12.5 11.3 12.3 3.7 11.3 8.5 11.7 14.3 12.6 10.5 10.8 9.5 13.2 17.1 9.6 8.0 15.2 16.3 7.0 8.4 21.3 13.5 10.8 16.5 11.2 3.9 8.4 21.5 10.5 15.4 7.4 34.4 30.5 8.9 24.5 31.1 13.6 16.7 10.8 37.9 19.3 10.4 23.4 9.4 23.8 14.3 19.6 10.1 19.4 9.7 16.6 23.7 13.3 15.9 50.9 26.3 26.1 19.2 15.7 25.6 19.6 23.1 23.4 9.5 16.5 23.9 8.0 18.7 23.5 7.7 30.2 9.9 14.9 10.9 17.9 19.3 15.7 9.0 14.1 12.6 25.0 8.8 13.6 13.9 43.4 21.4 7.5 5.5 3.7 13.1 16.1 5.0 9.4 41.3 20.7 10.9 19.2 11.9 20.4 16.2 15.0 14.6 8.9 17.1 19.8 14.3 8.8 18.4 18.2 3.5 20.5 21.1 7.4 20.7 17.7 7.8 8.6 8.9 11.8 8.1 8.2 8.5 8.2 8.5 8.0 8.4 8.4 2.2 3.2 9.5 0.0 22.2 7.1 4.7 11.5 16.5 0.0 2.0 2.0 28.6 14.3 14.0 0.0 0.0 9.6 7.3 17.6 0.0 1.6 60.7 2.4 4.8 8.6 4.9 24.8 0.0 1.2 7.5 11.0 44.9 2.1 19.0 1.7 13.2 21.2 10.5 0.0 0.0 22.3 10.2 17.2 6.5 28.3 22.1 14.0 7.2 0.0 12.6 0.0 19.6 0.0 0.0 1.7 16.7 15.8 21.5 4.0 26.6 1.5 11.4 0.0 19.7 10.6 6.7 11.6 6.3 19.1 7.0 5.7 31.3 1.7 18.2 5.0 ERCC6 "ARMD5, CKN2, CSB, RAD26" ENSG00000225830 "ERCC excision repair 6, chromatin remodeling factor" "P0DP91, Q03468" 10 49454168-49539538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Age-related macular degeneration, Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Mental retardation, Premature ovarian failure, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 53.8;hTERT-RPE1: 123.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071297 Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies" "HPA071297: AB_2732177" "unprognostic (1.92e-2)" "unprognostic (1.85e-1)" "unprognostic (9.79e-3)" "unprognostic (7.26e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-2)" "unprognostic (3.03e-2)" "unprognostic (2.99e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-1)" "unprognostic (1.80e-1)" "unprognostic (4.57e-2)" "unprognostic (1.04e-1)" "unprognostic (8.61e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" 2.7 2.1 1.6 1.9 1.5 4.6 3.8 3.0 2.3 3.1 7.7 2.4 2.0 3.0 1.5 3.8 2.9 2.7 3.4 1.2 1.1 3.2 3.3 2.7 2.9 2.4 1.9 4.5 3.1 5.9 2.8 3.4 2.1 3.3 2.7 3.1 3.2 2.2 3.5 4.6 2.5 2.3 2.2 2.9 2.4 3.1 2.1 3.3 5.1 3.6 3.4 2.6 3.3 1.9 11.2 5.5 4.1 2.1 6.6 10.5 3.4 21.2 27.1 14.1 9.9 6.2 5.6 4.9 3.7 18.7 6.7 9.5 6.3 16.6 13.5 8.4 4.1 3.9 21.7 3.4 3.9 5.0 3.7 4.3 17.2 12.9 53.8 123.4 19.8 2.9 6.8 0.8 16.8 8.3 3.4 2.0 4.0 3.5 10.2 2.3 5.8 2.6 4.1 7.1 5.9 4.7 15.4 3.6 8.2 9.4 7.1 2.7 38.9 7.0 5.5 8.6 5.2 3.3 4.5 4.1 7.3 5.0 5.1 13.1 3.0 7.5 4.1 2.6 3.0 6.8 2.3 2.2 3.9 5.2 2.8 1.4 7.2 1.2 5.3 2.2 3.1 1.8 1.6 1.5 3.0 2.3 1.2 1.1 2.4 1.9 2.1 2.2 2.1 1.9 6.9 16.0 13.2 14.7 6.0 3.6 1.4 1.5 5.2 0.0 7.1 7.1 7.1 5.7 8.2 9.2 0.0 2.5 10.9 4.8 5.9 5.2 11.3 8.1 8.7 5.1 1.2 1.3 24.3 6.0 2.1 4.9 2.0 10.1 7.6 8.9 5.3 4.3 2.6 0.0 21.7 5.3 0.0 4.4 2.6 15.3 2.8 8.0 1.8 23.4 11.2 0.0 4.1 17.6 16.6 5.2 2.6 2.2 3.6 2.5 5.0 3.6 9.0 0.0 6.6 4.4 4.2 5.3 5.0 3.5 4.1 1.8 7.4 11.4 2.8 1.9 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ESR1 "ER-alpha, Era, ESR, NR3A1" ENSG00000091831 "Estrogen receptor 1" P03372 6 151656691-152129619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.8;endometrium 1: 110.9;fallopian tube: 64.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 86.6;Endometrial ciliated cells: 77.9;Endometrial stromal cells: 79.9;Glandular and luminal cells: 98.9;Hepatocytes: 52.1;Horizontal cells: 62.2;Skeletal myocytes: 56.7" "Cancer enhanced" "Detected in many" "breast cancer: 40.2;endometrial cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "MCF7: 46.0;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB000037, HPA000449, HPA000450, CAB055099, CAB072858" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoplasm "CAB000037: AB_563706, CAB055099: AB_2101946, CAB072858: AB_2665701, HPA000449: AB_1078753, HPA000450: AB_1078754" "unprognostic (8.28e-2)" "unprognostic (3.02e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.47e-7)" "unprognostic (4.79e-1)" "unprognostic (2.43e-3)" "unprognostic (4.10e-5)" "unprognostic (9.92e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (7.35e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-2)" "unprognostic (7.91e-3)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.52e-1)" 4.2 1.8 3.2 1.5 1.3 0.8 29.1 2.9 1.3 83.8 3.2 0.9 0.4 110.9 1.2 0.5 64.9 1.2 1.8 0.6 6.7 2.8 16.9 2.0 1.6 0.4 0.5 9.0 1.0 0.2 6.6 0.4 0.3 6.1 0.5 3.5 0.9 9.8 5.8 1.1 0.8 50.4 0.2 1.7 0.6 2.3 5.9 1.0 3.4 2.6 2.3 2.1 46.9 0.3 0.6 0.0 0.1 0.1 0.1 1.9 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.6 0.0 0.0 0.0 1.2 0.1 46.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.7 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.2 57.4 0.0 0.1 0.2 0.2 0.5 0.0 5.2 1.1 0.1 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.3 2.9 1.3 0.6 6.7 0.4 0.5 0.3 0.2 5.9 0.3 0.6 0.0 1.1 1.3 2.3 1.0 1.7 0.0 0.0 3.9 86.6 16.4 4.4 0.0 1.0 0.0 8.4 0.1 0.4 0.1 1.9 0.0 40.1 77.9 79.9 2.7 1.8 0.0 4.5 0.2 0.1 11.3 0.0 98.9 2.5 36.9 5.0 52.1 0.9 62.2 5.4 0.0 0.0 4.0 3.1 10.3 4.1 2.5 1.8 1.0 0.2 2.4 0.0 25.1 0.6 0.1 0.0 2.2 8.5 0.6 0.0 3.7 1.3 4.6 0.0 56.7 11.7 1.8 1.3 0.4 1.7 0.1 2.2 4.8 0.1 6.8 ESR2 "ER-beta, Erb, NR3A2" ENSG00000140009 "Estrogen receptor 2" Q92731 14 64084232-64338112 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 6.1" "Cell type enhanced" "Detected in many" "Early spermatids: 61.4;Granulosa cells: 26.6;Late spermatids: 93.7;Rod photoreceptor cells: 35.6;Spermatocytes: 28.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "Karpas-707: 4.2;U-266/70: 9.8;U-698: 16.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 6.1" "HPA068406, CAB079300" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Vesicles "CAB079300: , HPA068406: " "unprognostic (7.63e-3)" "unprognostic (2.28e-3)" "unprognostic (8.27e-3)" "unprognostic (5.41e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (4.38e-2)" "unprognostic (1.95e-1)" "unprognostic (8.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.65e-1)" "unprognostic (3.03e-5)" "unprognostic (1.57e-1)" "unprognostic (1.66e-1)" "unprognostic (4.21e-2)" "unprognostic (5.89e-2)" 1.5 6.1 1.2 1.2 0.6 1.0 0.9 3.0 0.8 1.4 3.5 0.9 1.0 1.2 0.4 0.7 1.0 0.5 0.6 0.5 0.9 1.5 0.7 0.6 2.1 0.7 0.6 5.4 2.1 0.1 0.8 0.2 1.0 1.5 1.0 2.0 0.8 0.2 1.4 1.0 1.3 0.3 0.3 1.8 1.0 5.7 1.7 2.5 0.6 0.2 1.6 1.1 0.6 0.9 0.8 0.4 0.7 0.6 0.0 0.1 1.5 0.2 0.0 0.1 0.1 0.3 0.9 3.1 0.1 0.1 0.4 1.0 0.8 0.0 0.1 0.7 0.4 0.3 1.0 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.2 0.3 1.1 0.5 4.2 0.2 0.8 0.5 0.2 0.7 0.6 0.4 0.5 0.4 0.3 0.1 1.3 2.2 0.6 0.4 0.2 1.1 0.4 0.7 0.1 0.5 0.4 1.0 0.2 0.1 9.8 3.1 16.4 0.2 0.1 0.8 0.3 0.1 0.5 0.3 0.2 0.2 0.5 0.2 0.4 0.0 0.7 0.4 0.3 0.6 0.2 0.3 1.1 0.2 0.1 1.2 0.6 3.0 0.8 0.5 0.9 0.7 0.6 1.0 0.3 1.7 0.9 0.9 6.4 0.0 6.8 5.5 0.3 2.2 0.4 2.8 1.6 0.3 0.1 0.9 4.3 0.9 0.0 6.2 0.7 5.2 0.1 0.0 0.3 61.4 3.5 0.9 3.0 0.0 0.4 12.4 0.7 0.5 2.2 0.0 4.9 1.3 26.6 1.1 0.1 0.1 0.0 17.9 0.8 0.0 0.0 0.3 93.7 0.9 0.2 1.8 7.5 0.1 0.9 6.2 10.6 7.6 0.5 0.1 1.2 16.6 3.8 0.4 0.1 1.7 35.6 0.0 1.5 1.4 28.0 1.4 0.5 0.1 1.1 3.0 16.4 0.8 1.8 ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 299.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA010712: AB_2668349, HPA029407: AB_2673026" "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (1.23e-3)" "unprognostic (2.19e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.98e-3)" "unprognostic (8.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.01e-1)" "unprognostic (1.64e-2)" "unprognostic (4.53e-3)" "unprognostic (2.77e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-1)" "prognostic favorable (1.75e-4)" 10.1 14.4 13.7 14.5 15.2 12.2 13.7 9.0 15.9 10.8 16.4 27.2 23.3 10.2 19.6 10.8 10.1 14.0 7.3 14.7 28.1 18.4 18.2 12.6 17.4 12.0 14.2 11.7 10.7 10.8 13.7 11.3 15.8 10.9 15.3 18.2 12.4 6.2 6.2 15.3 15.5 7.6 11.1 16.7 45.0 17.8 19.3 23.1 14.5 5.6 14.3 10.8 9.5 17.5 14.8 27.9 30.4 27.5 21.2 21.3 21.7 15.6 12.2 17.4 16.0 20.6 33.3 41.1 14.7 11.6 16.5 10.7 27.1 7.6 28.2 36.8 23.7 34.7 11.5 18.9 20.6 33.9 29.4 13.7 7.2 21.9 17.4 25.8 20.3 15.7 41.8 17.2 22.3 7.7 38.8 67.1 59.3 17.9 20.1 32.7 28.1 32.9 25.6 16.5 9.8 17.8 18.9 13.9 27.1 41.1 24.1 32.1 17.5 12.2 19.9 18.6 25.0 12.9 18.1 46.8 16.2 21.0 23.9 44.0 14.3 15.9 15.4 22.0 15.2 22.2 16.4 14.4 14.1 15.3 17.7 17.7 14.6 17.7 23.4 12.6 20.5 19.2 13.7 15.2 9.0 15.9 14.7 28.1 12.0 14.2 15.8 11.1 19.3 17.5 33.6 48.1 32.2 48.0 55.9 144.3 75.7 34.7 64.9 41.0 56.8 42.2 10.1 45.8 43.8 44.1 50.1 30.1 57.6 116.1 27.4 30.7 299.0 64.2 49.1 34.8 108.3 48.8 104.4 44.5 24.2 38.2 230.4 51.4 34.8 40.9 28.2 41.5 42.9 26.9 104.3 60.7 46.8 88.3 60.0 43.5 24.2 57.0 67.6 84.3 39.1 17.7 43.3 121.2 152.9 39.5 62.9 21.4 63.7 73.8 57.7 33.2 81.6 39.5 39.5 23.3 38.9 49.1 18.5 51.9 170.2 75.4 49.0 41.5 47.8 90.3 ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 119.9;salivary gland: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 137.7;Astrocytes: 67.3;Cardiomyocytes: 87.7;Enteroendocrine cells: 198.1;Excitatory neurons: 66.9;Oligodendrocyte precursor cells: 135.7" "Cancer enhanced" "Detected in all" "glioma: 22.5" "Group enriched" "Detected in all" 5 "cerebellum: 119.9;thalamus: 32.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 67.8;hTERT-RPE1: 76.2;SCLC-21H: 79.3;U-87 MG: 157.2;WM-115: 78.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 200.7" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA068389: , HPA077249: AB_2686829" "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-2)" "unprognostic (2.13e-2)" "unprognostic (1.64e-7)" "unprognostic (7.08e-3)" "unprognostic (7.21e-2)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-3)" "unprognostic (2.21e-2)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" 4.9 23.0 13.6 1.9 10.9 0.2 8.2 119.9 12.1 2.3 0.1 4.1 2.2 4.4 2.3 2.7 1.5 17.3 35.6 14.6 5.6 3.2 3.9 28.7 1.4 4.6 14.0 1.4 3.1 11.5 7.4 3.5 9.0 5.5 4.3 4.5 91.6 12.6 0.8 1.9 3.5 3.5 3.1 9.1 2.6 8.9 32.8 4.7 12.2 2.5 1.9 2.7 1.5 8.1 0.1 4.9 35.5 67.8 12.1 35.4 0.1 3.2 12.1 2.0 8.0 0.0 16.6 0.0 3.6 5.6 9.8 0.4 1.5 3.8 4.3 0.9 1.6 2.1 3.1 0.0 7.1 12.3 4.5 10.7 0.0 23.3 1.9 76.2 15.3 1.1 11.0 0.6 14.6 0.0 0.1 0.0 53.2 2.1 36.5 0.0 21.5 2.9 23.7 0.4 79.3 15.6 0.0 1.2 19.6 12.2 1.2 0.5 8.6 7.0 2.2 13.8 13.4 12.2 4.1 0.0 157.2 0.8 78.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 10.9 119.9 12.1 14.6 5.6 4.6 14.0 9.0 3.1 32.8 8.1 16.0 19.2 137.7 67.3 0.0 1.0 2.8 0.9 13.6 4.9 5.8 23.6 87.7 28.6 0.7 3.7 0.0 0.6 0.1 0.8 5.9 3.6 25.4 1.3 3.9 11.1 198.1 0.8 66.9 0.9 0.4 17.7 1.1 2.0 2.5 0.2 2.9 13.1 3.4 5.0 45.3 2.4 0.0 7.2 1.6 8.7 1.5 0.7 12.4 28.1 0.0 12.6 0.0 135.7 4.3 0.9 0.1 34.6 1.2 0.6 0.0 3.0 1.4 0.6 19.7 17.4 12.6 1.2 2.1 3.1 1.3 0.3 2.2 9.7 1.2 0.3 ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 23.3;Cholangiocytes: 17.2;Distal tubular cells: 17.6;Enteroendocrine cells: 14.9;Extravillous trophoblasts: 19.8;Syncytiotrophoblasts: 14.9" "Cancer enhanced" "Detected in all" "testis cancer: 80.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 177.7;Hep G2: 173.0;SK-MEL-30: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Salivary gland - Salivary secretion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli rim" "Mitotic chromosome" "HPA005768: AB_1848294" "unprognostic (2.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.58e-2)" "unprognostic (5.34e-2)" "unprognostic (8.13e-2)" "unprognostic (7.05e-2)" "unprognostic (3.01e-1)" "unprognostic (7.79e-2)" "unprognostic (2.03e-1)" "unprognostic (7.08e-2)" "prognostic favorable (7.60e-4)" "unprognostic (1.69e-1)" 0.5 2.4 1.2 1.0 1.6 0.0 7.0 0.8 2.2 3.6 0.0 2.0 6.1 2.4 1.0 9.2 2.5 6.4 3.1 1.3 0.8 5.4 1.2 2.2 0.6 1.0 0.9 0.4 7.8 7.9 14.7 5.2 1.4 4.5 1.7 3.0 4.6 3.6 1.3 6.4 4.2 1.4 0.3 0.4 3.8 1.2 0.7 0.3 6.9 2.5 4.8 2.1 5.3 0.9 24.5 67.0 80.4 177.7 3.1 20.1 17.9 7.9 21.1 14.9 15.2 38.1 33.9 0.1 4.3 4.1 36.6 43.6 2.7 40.2 13.2 0.8 0.5 2.3 10.7 173.0 4.3 47.0 20.9 3.6 1.4 56.8 35.0 16.8 32.1 0.3 48.9 0.1 31.0 9.8 0.2 82.9 116.9 123.1 110.9 99.8 9.8 58.9 33.0 17.3 0.1 71.4 2.1 4.5 197.0 43.8 0.8 13.9 15.1 10.6 52.0 15.7 22.1 7.3 47.8 0.1 18.9 8.9 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.8 2.2 1.3 0.8 1.0 0.9 1.4 0.3 0.7 0.9 0.2 0.0 0.0 1.3 0.0 1.9 2.5 3.6 23.3 3.2 10.4 12.3 1.1 17.2 2.4 0.0 0.0 2.3 0.1 1.1 17.6 6.5 3.1 0.7 0.3 1.5 14.9 0.0 1.6 1.0 19.8 1.9 3.1 1.6 0.0 0.2 0.7 0.0 0.8 0.0 1.0 4.0 2.0 0.3 0.3 6.0 0.3 0.2 3.6 1.0 0.0 10.9 0.0 1.0 0.0 3.7 3.3 0.4 0.0 0.9 1.9 0.1 1.0 0.3 0.0 2.1 1.7 0.0 1.3 3.6 1.1 14.9 0.3 0.1 7.7 4.3 ETV5 ERM ENSG00000244405 "ETS variant transcription factor 5" P41161 3 186046314-186110318 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.0;Oligodendrocyte precursor cells: 169.9;Syncytiotrophoblasts: 88.8" "Cancer enhanced" "Detected in all" "melanoma: 50.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 178.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009590, HPA063065, HPA073889" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB009590: AB_2101008, HPA063065: AB_2684936, HPA073889: " "unprognostic (3.85e-1)" "unprognostic (5.81e-2)" "unprognostic (1.54e-2)" "unprognostic (3.30e-1)" "unprognostic (9.00e-2)" "unprognostic (2.56e-3)" "prognostic unfavorable (7.85e-9)" "unprognostic (3.52e-3)" "unprognostic (2.97e-1)" "unprognostic (1.22e-2)" "unprognostic (4.18e-2)" "unprognostic (1.48e-1)" "unprognostic (1.57e-3)" "unprognostic (6.80e-2)" "unprognostic (1.57e-1)" "unprognostic (3.58e-2)" "unprognostic (3.84e-3)" 6.8 39.3 17.1 6.9 22.4 1.4 15.0 17.7 24.4 4.9 9.4 3.4 6.1 8.1 7.3 4.2 5.1 5.6 11.5 17.8 16.8 8.9 7.9 29.6 5.2 20.5 17.1 2.2 17.5 42.2 25.4 17.1 17.7 7.4 3.2 15.9 6.5 5.8 11.9 6.4 3.0 7.4 14.7 10.9 14.8 9.3 17.2 4.8 21.9 7.0 4.2 4.3 4.1 19.6 42.4 28.6 36.1 79.2 21.9 22.7 2.6 35.7 39.7 27.7 29.6 31.7 25.4 1.1 46.4 34.7 41.3 7.1 0.8 27.2 40.7 9.3 1.0 12.4 1.0 36.4 36.3 31.2 22.1 19.9 4.4 44.3 53.7 32.9 41.0 4.4 11.6 14.6 47.5 19.8 4.1 47.7 54.2 12.1 32.4 86.6 36.0 28.7 23.0 9.9 1.6 45.8 8.7 0.4 178.3 14.4 0.1 17.3 40.0 15.0 24.3 38.2 70.5 11.1 49.9 0.3 45.8 24.6 91.6 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.1 17.1 22.4 17.7 24.4 17.8 16.8 20.5 17.1 17.7 14.7 17.2 19.6 5.7 3.2 68.5 26.1 5.6 15.7 10.6 8.2 45.5 17.8 9.4 30.4 5.7 17.2 2.4 0.0 12.5 57.6 3.1 0.6 3.9 9.4 24.6 2.0 4.3 9.2 10.7 1.7 94.0 9.4 18.8 12.5 15.8 4.7 8.2 0.8 10.4 9.0 56.4 5.0 43.7 2.8 0.0 64.4 19.4 49.0 9.0 27.1 16.0 45.9 2.1 60.4 1.0 169.9 47.5 12.5 1.1 15.4 4.9 3.6 1.5 22.9 1.3 18.8 0.0 25.4 13.6 16.9 14.4 8.7 5.3 88.8 1.9 3.1 1.5 2.7 ETV6 TEL ENSG00000139083 "ETS variant transcription factor 6" P41212 12 11649674-11895377 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 137.2;Microglial cells: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 85.1;NB-4: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000264 Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoli Cytosol "HPA000264: AB_611466" "unprognostic (4.03e-3)" "unprognostic (3.08e-2)" "unprognostic (7.54e-3)" "unprognostic (2.60e-1)" "unprognostic (2.07e-1)" "unprognostic (1.35e-3)" "unprognostic (2.74e-2)" "unprognostic (4.02e-2)" "unprognostic (3.16e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (9.38e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.66e-8)" "unprognostic (1.33e-2)" "unprognostic (5.99e-2)" "unprognostic (8.92e-2)" "prognostic favorable (1.54e-5)" 16.9 8.8 4.8 16.3 4.4 40.9 20.0 4.8 5.6 9.4 3.6 15.2 7.5 7.9 11.1 9.5 8.0 9.7 6.6 4.2 4.7 9.2 9.3 16.2 12.8 9.2 6.0 5.0 9.6 5.6 5.3 8.1 6.9 13.5 11.2 2.6 33.3 6.8 5.5 24.3 14.1 9.2 6.8 16.7 8.4 3.5 6.8 17.3 8.9 2.7 14.7 15.0 8.4 6.3 5.6 7.5 6.7 11.6 5.0 4.7 8.1 4.1 6.9 5.2 6.1 0.5 25.9 4.7 4.0 7.0 6.1 7.1 3.0 12.4 6.2 85.1 1.4 29.9 4.0 2.8 6.2 32.0 31.2 9.3 7.5 5.1 10.5 9.9 15.9 21.3 2.3 15.3 4.7 3.6 18.1 45.3 10.9 5.9 2.0 5.1 6.3 12.3 11.9 34.8 1.3 6.8 8.1 7.7 7.7 10.6 2.6 19.9 18.1 11.6 9.8 3.9 8.8 6.7 5.5 2.6 7.6 0.2 13.6 6.2 4.5 5.9 1.1 5.6 1.6 2.3 1.7 1.1 3.5 1.7 1.0 0.6 9.8 2.1 6.8 5.3 1.2 1.2 4.8 4.4 4.8 5.6 4.2 4.7 9.2 6.0 6.9 6.8 6.8 6.3 38.3 6.4 9.6 84.2 37.7 14.9 31.8 27.2 10.8 3.1 66.7 57.8 9.1 21.5 30.7 14.7 6.2 15.0 21.5 45.7 1.9 17.9 17.6 45.3 17.5 37.5 32.4 33.6 63.6 35.9 4.3 12.9 20.9 69.7 10.8 24.0 38.6 10.9 18.3 0.0 117.7 28.9 22.4 53.3 137.2 4.5 7.8 62.6 28.4 216.4 55.7 4.3 8.2 106.6 37.0 38.6 31.6 10.9 71.4 34.2 15.4 11.5 39.3 3.9 19.7 17.6 34.2 0.6 5.4 17.3 22.4 8.6 20.9 21.5 22.5 71.8 EWSR1 EWS ENSG00000182944 "EWS RNA binding protein 1" Q01844 22 29268009-29300525 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Calmodulin-binding, Repressor, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004230, HPA051771, HPA062953" Enhanced Enhanced "Nucleoplasm,Nucleoli rim" No No 59000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli rim" "CAB004230: AB_675526, HPA051771: AB_2681602, HPA062953: AB_2684910" "unprognostic (1.96e-1)" "unprognostic (6.39e-3)" "unprognostic (1.32e-1)" "unprognostic (3.93e-2)" "unprognostic (3.59e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (1.33e-1)" "unprognostic (1.09e-2)" "unprognostic (2.71e-2)" "unprognostic (7.04e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.21e-5)" "unprognostic (7.33e-3)" "unprognostic (1.79e-1)" "unprognostic (3.67e-2)" "unprognostic (1.50e-3)" 84.8 102.2 63.2 93.2 64.7 172.3 80.3 70.3 69.5 87.9 61.2 90.5 88.0 105.1 61.9 99.0 86.0 56.1 101.7 64.7 63.7 88.0 85.0 76.8 120.1 67.4 64.7 86.8 79.1 98.0 64.1 70.2 63.6 78.4 84.4 111.2 76.5 77.3 140.0 88.0 92.6 86.9 59.7 101.0 84.3 135.5 63.9 183.0 77.2 79.9 126.8 88.1 86.2 71.8 307.7 239.7 327.6 249.1 166.0 136.0 218.2 188.1 301.3 309.9 264.5 270.3 154.5 428.0 114.1 294.3 234.9 238.9 471.5 392.6 313.7 287.5 341.6 323.9 218.8 262.7 246.5 499.5 219.3 211.1 162.5 259.1 413.0 152.2 244.2 201.1 248.3 186.0 233.8 310.6 505.9 185.8 221.1 261.4 182.8 348.1 317.2 253.3 288.0 328.2 261.4 247.7 236.3 258.5 195.9 216.2 170.9 261.0 246.3 184.4 198.2 115.1 272.3 236.2 205.5 387.4 169.9 220.6 224.4 203.9 201.1 182.6 195.2 283.5 199.5 169.4 181.3 194.4 227.5 191.3 175.8 170.9 148.1 216.9 293.0 122.0 244.0 314.2 63.2 64.7 70.3 69.5 64.7 63.7 67.4 64.7 63.6 59.7 63.9 71.8 77.5 102.5 106.8 68.6 130.8 69.5 145.2 153.2 108.1 72.4 63.8 46.6 68.0 87.2 127.2 64.4 75.0 141.0 91.3 92.4 66.5 121.7 165.4 96.3 88.1 88.3 80.9 102.0 55.8 107.6 133.5 85.4 117.2 115.2 121.0 88.5 71.7 71.7 99.3 82.4 60.8 110.9 136.3 69.7 94.0 32.7 61.5 91.9 81.8 47.8 110.9 72.8 122.6 49.8 67.6 116.5 106.4 62.1 156.6 97.4 79.4 72.6 128.9 84.9 52.6 93.1 141.4 209.6 107.5 105.5 58.5 152.4 121.4 84.9 110.2 115.1 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.5;fHDF/TERT166: 82.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" 5.1 4.2 2.0 5.2 2.5 1.1 4.3 2.3 2.3 7.6 3.9 7.7 14.1 4.9 2.9 5.5 3.8 5.8 7.0 3.4 1.3 3.8 13.3 7.9 3.0 1.1 2.1 5.0 5.5 3.3 1.8 11.1 1.0 5.0 8.2 2.7 3.2 7.7 1.5 7.8 11.7 6.1 1.4 5.1 5.3 2.4 1.2 3.0 5.2 2.4 3.8 11.8 4.2 1.9 29.3 8.5 13.5 5.5 22.8 23.0 5.9 51.5 95.5 40.9 39.4 10.0 3.1 0.5 24.8 82.1 24.0 19.8 5.0 31.4 55.7 12.5 9.9 1.5 5.9 6.5 10.0 0.0 1.6 10.8 10.8 38.8 38.5 47.7 28.1 2.9 0.9 7.4 18.7 3.2 1.8 0.2 4.6 13.7 10.1 0.0 4.1 1.3 23.1 7.6 4.5 4.0 8.0 3.9 9.2 32.6 5.3 0.5 32.0 35.2 28.7 32.0 15.8 5.5 5.1 2.4 36.5 0.0 9.2 0.1 0.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.3 0.1 2.0 2.5 2.3 2.3 3.4 1.3 1.1 2.1 1.0 1.4 1.2 1.9 21.1 19.2 6.0 127.3 3.0 54.8 23.0 27.7 10.2 23.6 7.8 10.8 6.5 24.3 13.7 7.3 14.6 6.5 5.1 49.2 0.0 37.3 1.8 17.7 37.1 25.9 4.8 1.7 229.6 20.1 3.9 32.6 11.7 18.2 7.0 108.3 16.8 32.9 2.5 10.1 421.4 25.5 4.1 37.9 13.9 2.7 17.4 9.6 19.6 144.3 8.1 5.9 4.1 162.8 101.8 27.4 16.1 36.1 5.3 19.3 44.9 4.9 14.2 22.4 0.0 17.1 36.4 0.6 5.1 12.6 47.3 12.2 4.2 35.0 26.3 26.8 EXT2 SOTV ENSG00000151348 "Exostosin glycosyltransferase 2" Q93063 11 44095673-44251962 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, Hereditary multiple exostoses, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078409 Supported "Golgi apparatus" NA NA 39000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA078409: AB_2686884" "unprognostic (5.87e-2)" "unprognostic (3.05e-3)" "unprognostic (3.48e-2)" "unprognostic (3.94e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.77e-3)" "unprognostic (2.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.70e-2)" "prognostic unfavorable (5.36e-6)" "unprognostic (7.07e-3)" "unprognostic (2.97e-1)" "unprognostic (3.85e-1)" "unprognostic (1.36e-2)" 33.5 22.8 14.4 22.1 15.4 11.2 29.3 15.4 16.3 36.1 17.5 29.1 26.5 43.1 33.3 20.1 33.7 28.1 27.3 15.6 18.1 26.5 26.9 27.9 16.0 15.5 16.0 33.5 26.5 28.9 20.1 61.9 15.5 29.8 28.7 20.9 26.7 30.2 16.2 25.8 31.0 49.3 14.7 21.6 23.8 21.6 19.4 15.2 27.6 18.4 17.3 29.7 28.5 16.1 57.9 71.6 38.3 121.5 170.4 124.2 60.8 181.1 198.0 93.1 125.1 51.2 36.5 40.4 82.1 188.8 98.5 90.0 41.0 114.0 110.0 83.2 71.5 38.4 33.7 39.7 67.5 37.5 76.6 97.7 73.4 56.3 86.6 108.8 132.7 34.8 50.0 63.9 68.4 40.3 25.9 22.3 43.8 67.1 70.9 32.3 116.1 21.1 53.9 49.1 30.9 35.5 118.1 41.4 28.1 67.0 69.8 37.2 137.8 127.4 90.6 133.1 111.4 33.4 46.0 30.4 84.7 27.9 140.0 15.2 17.5 19.4 20.9 17.7 23.5 9.0 16.5 19.3 21.3 8.8 15.4 15.2 3.4 26.3 12.8 7.4 14.2 15.5 14.4 15.4 15.4 16.3 15.6 18.1 15.5 16.0 15.5 14.7 19.4 16.1 24.5 16.0 10.6 41.4 8.7 15.2 17.3 22.0 10.8 11.5 11.0 11.4 10.2 8.6 13.5 12.9 14.6 34.3 10.6 21.1 5.9 33.5 43.2 7.9 17.1 19.2 1.8 6.7 64.3 23.7 37.0 32.3 7.7 11.5 6.3 22.7 22.9 18.3 18.3 13.5 63.3 12.9 12.2 10.8 7.2 23.0 27.4 10.4 5.4 28.1 10.2 17.4 7.2 50.3 51.8 24.0 14.9 28.6 7.0 23.6 31.6 8.2 8.1 15.0 19.7 15.8 20.7 51.2 24.4 10.2 12.6 35.3 9.2 12.2 15.0 15.3 EZH1 "KIAA0388, KMT6B" ENSG00000108799 "Enhancer of zeste 1 polycomb repressive complex 2 subunit" Q92800 17 42700275-42745049 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 133.4" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 258.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 48.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005478, HPA077684" Supported Supported Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA005478: AB_1848340, HPA077684: AB_2732356" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (2.19e-2)" "unprognostic (8.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.84e-3)" "unprognostic (1.76e-2)" "unprognostic (1.18e-2)" "unprognostic (1.25e-1)" "unprognostic (1.55e-3)" "unprognostic (5.22e-3)" "unprognostic (4.11e-3)" "unprognostic (1.48e-2)" "unprognostic (4.60e-2)" "unprognostic (3.29e-1)" "unprognostic (5.39e-2)" "unprognostic (4.74e-2)" 39.6 18.1 35.0 14.4 37.4 15.2 34.1 42.4 41.5 41.5 29.4 31.6 13.0 31.1 26.5 21.6 35.6 12.8 31.8 33.9 33.9 28.6 13.4 25.7 20.5 37.7 36.5 47.8 18.3 25.5 26.3 12.5 40.2 26.0 15.4 133.4 20.2 23.8 43.8 26.1 30.6 20.4 32.3 37.8 20.7 12.0 35.8 22.9 28.4 33.2 20.4 29.2 31.4 41.5 8.9 9.3 12.4 8.5 48.4 29.1 10.4 14.0 12.7 11.4 11.6 4.4 10.8 13.4 8.6 15.0 11.2 19.8 8.1 9.2 16.3 15.0 14.5 4.7 19.7 5.4 16.6 10.2 10.8 16.7 16.6 8.6 20.8 20.0 9.4 13.4 12.5 18.5 10.2 3.7 16.6 12.9 3.4 8.2 4.7 10.7 12.4 14.5 11.7 9.3 8.4 6.8 7.8 3.8 9.5 17.5 13.2 6.5 9.8 12.2 5.0 14.4 8.9 19.3 10.4 8.0 8.8 10.4 6.4 14.2 5.2 7.8 6.0 5.4 8.2 5.8 5.3 6.1 2.0 6.3 7.7 5.8 19.7 5.8 3.6 6.3 6.4 2.6 35.0 37.4 42.4 41.5 33.9 33.9 37.7 36.5 40.2 32.3 35.8 41.5 34.2 9.6 20.8 41.1 23.6 5.2 14.2 6.6 8.6 71.7 8.7 13.1 39.3 20.0 14.1 12.9 66.7 7.9 24.6 9.3 9.8 11.2 0.7 21.8 23.2 20.7 13.1 36.4 36.8 7.5 3.2 25.3 8.6 25.5 20.3 19.4 15.4 7.8 9.0 47.1 34.0 4.9 12.2 17.1 7.2 2.8 31.1 14.7 1.8 15.0 24.1 30.8 33.0 20.6 58.9 12.1 7.7 34.3 15.9 9.1 12.9 10.7 28.0 258.1 52.6 32.7 24.1 10.7 10.6 6.6 6.1 10.8 21.8 26.2 7.4 9.6 EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807383-148884321 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.9;lymphoid tissue: 43.0;testis: 27.8" "Cell type enhanced" "Detected in many" "Early spermatids: 109.3;Spermatocytes: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009589, HPA029131" Enhanced Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB009589: , HPA029131: AB_2672920" "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.57e-1)" "unprognostic (3.30e-3)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "prognostic unfavorable (2.11e-6)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.32e-3)" "unprognostic (1.58e-3)" "unprognostic (1.69e-3)" "prognostic unfavorable (8.18e-12)" "prognostic favorable (6.97e-4)" "unprognostic (1.83e-1)" "unprognostic (2.12e-1)" "unprognostic (6.67e-2)" 1.5 1.5 1.1 10.1 1.1 47.9 2.7 2.0 1.3 2.7 1.5 7.0 6.4 2.0 1.2 10.8 1.1 1.9 1.2 1.1 1.1 2.1 3.3 2.3 22.1 1.2 1.2 1.6 3.7 1.3 0.5 4.8 1.2 1.3 8.2 3.3 2.8 0.2 2.9 10.7 6.9 2.8 1.0 5.6 4.0 27.8 1.5 43.0 1.3 1.9 21.1 3.5 3.8 1.2 65.6 30.1 99.7 66.9 3.1 5.1 54.6 49.7 19.9 39.9 40.2 45.6 73.2 114.3 23.5 18.7 36.3 39.0 52.1 17.1 50.6 164.9 51.8 48.9 38.4 35.5 8.0 110.1 38.5 4.3 9.6 29.9 15.9 12.1 24.0 108.9 105.9 73.6 36.2 74.0 215.7 91.7 79.6 57.0 39.9 131.3 56.0 70.9 18.6 31.0 95.1 60.3 62.3 46.8 16.5 25.3 34.3 46.7 14.8 42.4 19.8 85.2 90.4 65.7 76.6 115.3 38.6 74.2 84.9 0.4 1.7 1.1 1.2 1.2 0.9 1.1 2.6 2.2 3.8 0.6 1.4 0.9 0.1 7.2 3.6 0.8 8.3 1.2 1.1 1.1 2.0 1.3 1.1 1.1 1.2 1.2 1.2 1.0 1.5 1.2 14.4 0.0 6.7 1.3 14.5 26.5 6.7 6.3 10.2 6.0 15.1 12.2 6.1 2.8 7.1 7.3 35.5 28.8 35.9 14.7 3.9 9.5 109.3 16.3 17.0 9.4 9.0 57.0 6.2 8.5 32.2 9.9 15.8 24.2 21.6 45.9 3.3 2.2 11.9 15.2 9.2 20.5 6.1 9.0 33.6 27.7 3.1 19.1 14.2 14.0 14.9 2.6 12.3 16.6 7.0 12.4 10.5 0.7 37.4 4.8 6.8 1.2 9.7 21.3 6.6 13.8 24.1 142.2 58.2 35.8 29.0 30.5 25.7 4.7 22.1 5.9 EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Enhanced "Plasma membrane" NA NA 42000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB004035: AB_2100309, CAB047324: , CAB075739: AB_2665745, HPA021616: AB_1848342" "unprognostic (4.79e-3)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (5.59e-2)" "prognostic favorable (9.56e-8)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-2)" "unprognostic (9.00e-2)" 88.2 186.6 100.7 98.4 99.5 135.2 59.8 86.0 96.8 77.1 224.4 133.5 158.8 35.6 78.4 260.3 114.6 116.1 116.3 96.2 95.6 159.1 57.9 173.2 185.6 97.6 105.3 44.7 112.6 447.4 42.8 233.0 91.7 81.4 103.6 10.7 89.9 72.2 46.9 187.8 257.1 36.6 99.3 75.6 273.7 55.9 98.9 108.8 126.1 25.5 216.3 219.0 98.6 91.1 668.3 355.4 86.5 125.0 9.3 10.3 502.7 204.7 67.1 225.7 189.2 420.9 357.7 667.1 197.2 235.2 108.5 497.7 172.2 228.0 259.5 235.3 111.2 14.0 204.9 187.5 223.2 167.7 98.9 16.6 172.9 212.9 205.1 191.4 150.2 90.8 134.9 316.7 132.3 175.9 239.3 199.6 144.5 180.6 117.6 176.9 40.7 152.5 462.1 198.6 156.3 127.2 358.5 507.7 37.9 391.5 124.1 218.5 195.3 72.6 233.4 101.1 319.9 216.5 212.8 566.9 45.4 84.9 88.5 177.2 83.4 103.7 195.9 190.8 233.2 466.5 205.6 245.1 181.9 389.7 108.6 146.3 36.2 133.6 202.9 84.5 385.7 298.2 100.7 99.5 86.0 96.8 96.2 95.6 97.6 105.3 91.7 99.3 98.9 91.1 47.4 951.9 547.8 111.3 799.6 614.7 809.5 202.4 247.0 11.2 240.4 144.4 311.0 154.4 726.2 156.3 0.0 406.1 372.4 806.8 97.8 302.3 10.2 782.9 75.4 71.0 159.9 46.5 0.4 256.1 560.3 213.1 500.5 844.5 119.0 40.8 25.4 37.5 113.3 0.0 0.5 415.3 179.0 79.1 820.5 32.8 135.5 297.5 321.9 12.2 110.5 35.7 62.8 2.0 0.7 618.3 631.2 294.2 564.9 416.7 694.2 238.1 1248.4 5.1 249.8 205.5 136.3 52.5 61.7 430.4 726.5 1243.4 483.8 102.3 312.9 1142.8 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 232.8;placenta: 489.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 863.3;Langerhans cells: 205.1;Macrophages: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.1;myeloid DC: 179.6" "Group enriched" "Detected in many" 184 "dendritic cells: 179.6;granulocytes: 50.2;monocytes: 141.1" "Cell line enhanced" "Detected in some" "AF22: 24.0;LHCN-M2: 8.9;RH-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 4: Macrophages - Innate immune response" "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 232.8 57.9 2.6 52.3 4.2 16.1 46.9 1.3 13.0 50.4 28.5 45.9 9.7 18.5 5.6 51.2 29.1 52.7 39.2 2.1 3.6 21.0 3.0 38.7 30.0 8.3 4.6 10.7 10.0 13.3 8.1 489.2 6.9 8.8 63.9 21.6 18.8 13.4 10.3 22.7 22.0 89.6 2.6 8.8 25.4 17.8 3.7 20.9 17.1 32.8 12.5 144.5 12.1 4.0 0.0 0.1 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 43.8 0.8 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 50.2 141.1 1.4 0.5 25.4 0.6 0.4 0.3 0.4 179.6 0.4 0.4 0.2 32.9 0.3 0.7 12.5 0.3 364.9 2.6 4.2 1.3 13.0 2.1 3.6 8.3 4.6 6.9 2.6 3.7 4.0 2.0 0.0 1.9 0.3 1.8 18.7 0.0 0.0 0.6 0.1 0.3 0.4 10.6 5.7 0.0 0.0 0.0 5.0 4.5 0.0 0.0 0.0 5.1 0.6 10.6 3.8 0.0 1.3 3.9 0.0 5.6 13.7 0.0 0.4 1.3 0.0 2.9 0.9 863.3 0.0 1.4 0.0 0.0 92.4 205.1 5.8 4.4 232.0 19.6 64.6 53.1 0.9 6.2 0.5 0.7 0.1 0.0 0.7 1.2 0.0 0.0 11.0 2.2 6.5 59.2 2.5 3.3 1.6 0.9 1.2 15.2 10.1 2.6 0.4 0.0 0.1 F13B FXIIIB ENSG00000143278 "Coagulation factor XIII B chain" P05160 1 197038741-197067260 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 211 "liver: 200.2" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 54.9" "Cancer enriched" "Detected in single" 816 "liver cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003827, HPA052139" Supported "Secreted to blood" NA NA 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "HPA003827: AB_1078794, HPA052139: AB_2681744" "unprognostic (1.46e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 200.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 54.9 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719196-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1518 "liver: 1217.3" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 991.0" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "Hep G2: 281.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" NA NA 108000000000 41000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016780: , HPA051476: AB_2681498, HPA054698: AB_2682578" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.2 1217.3 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.9 0.0 0.2 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.2 281.0 0.0 1.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.2 0.0 37.5 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.3 21.8 991.0 0.0 0.0 0.2 0.2 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.0 0.0 0.0 0.1 F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 902.0;Exocrine glandular cells: 464.1;Pancreatic endocrine cells: 1755.7;Peritubular cells: 530.7;Urothelial cells: 497.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1062.0;HaCaT: 490.7;HBEC3-KT: 1270.5;U-2197: 473.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" 118.2 21.3 53.1 28.8 69.9 4.1 70.1 53.2 74.4 48.0 44.1 52.2 36.8 61.1 44.2 41.3 89.9 59.6 36.8 54.0 62.7 18.0 5.1 59.8 12.9 77.7 62.6 114.8 96.5 17.2 81.2 133.4 57.1 56.8 42.1 72.6 93.3 60.4 7.6 56.0 47.3 10.7 60.8 7.2 42.6 34.6 62.0 5.6 62.6 9.9 14.9 65.4 73.0 55.4 1062.0 1.8 2.2 0.5 108.0 53.1 57.2 147.0 87.6 155.4 167.9 18.6 220.6 0.0 73.3 183.5 33.4 490.7 13.2 1270.5 254.4 0.9 1.6 0.0 35.0 3.3 35.9 0.7 0.6 91.9 28.2 73.8 356.5 293.7 1.1 1.1 0.9 0.8 110.0 1.8 1.5 22.3 9.8 6.8 2.2 1.2 10.3 0.5 19.8 3.2 1.3 2.6 117.4 48.3 3.6 29.6 1.3 13.9 0.3 93.7 2.5 473.0 44.6 0.9 1.3 0.9 71.9 5.7 3.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 53.1 69.9 53.2 74.4 54.0 62.7 77.7 62.6 57.1 60.8 62.0 55.4 9.4 131.4 243.3 196.6 0.7 16.3 902.0 359.6 2.2 3.6 29.6 20.4 26.4 18.6 380.3 14.7 0.0 16.5 0.6 20.9 0.0 133.5 8.6 61.3 125.0 13.2 13.1 0.0 0.4 464.1 6.0 125.3 23.0 123.0 2.5 38.1 7.5 0.4 6.1 3.3 4.6 70.3 65.1 2.8 5.2 14.5 281.1 9.1 3.6 45.9 2.1 340.6 0.0 15.6 1.2 1755.7 15.5 530.7 1.2 121.6 10.1 0.4 92.0 16.1 6.6 39.3 76.7 1.7 4.4 6.4 7.5 7.7 7.3 7.9 14.3 497.9 FABP1 L-FABP ENSG00000163586 "Fatty acid binding protein 1" P07148 2 88122982-88128062 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "intestine: 5501.2;liver: 13065.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 12424.2;Hepatocytes: 7459.2;Paneth cells: 3975.2;Proximal enterocytes: 15929.5" "Group enriched" "Detected in many" 14 "colorectal cancer: 175.1;liver cancer: 437.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 122.1;Hep G2: 393.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002305, HPA028275" Enhanced Approved Nucleoplasm,Cytosol NA NA 45000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cytosol" "CAB002305: AB_563728, HPA028275: AB_10600909" "unprognostic (1.91e-1)" "unprognostic (7.91e-3)" "unprognostic (5.47e-2)" "unprognostic (1.96e-1)" "unprognostic (2.03e-2)" "unprognostic (2.35e-1)" "unprognostic (7.99e-2)" "unprognostic (8.92e-2)" "unprognostic (2.29e-1)" 6.7 0.8 0.6 160.2 0.6 0.0 10.7 0.5 1.8 0.7 0.4 5501.2 4751.8 13.0 0.0 2.6 3.9 0.5 0.8 0.6 0.7 727.6 13065.3 0.9 3.7 0.6 0.5 0.9 1.0 0.3 0.8 0.7 0.5 2.6 3416.4 0.1 0.5 8.4 0.9 0.5 4727.6 230.4 0.5 2.8 15.8 1.1 0.6 0.1 0.5 0.4 0.1 0.6 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 122.1 0.0 1.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 393.9 0.0 7.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 33.0 0.5 0.0 0.0 0.3 6.4 37.4 0.0 0.5 3.6 24.7 2.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 11.8 0.7 0.4 0.1 2.5 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.8 0.6 0.7 0.6 0.5 0.5 0.5 0.6 0.7 0.0 0.0 0.0 0.3 42.6 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.3 120.1 0.0 60.7 0.0 0.2 0.0 12424.2 156.5 0.0 0.0 0.0 0.0 7.5 261.9 149.7 0.1 0.0 1.2 0.1 2.6 0.0 129.2 0.0 105.3 7459.2 1.5 0.0 0.1 1061.1 0.0 166.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3975.2 0.0 0.0 0.1 15929.5 2014.4 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.0 1.4 29.3 0.0 1708.4 0.0 FABP2 I-FABP ENSG00000145384 "Fatty acid binding protein 2" P12104 4 119317250-119322138 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "intestine: 550.0" "Cell type enriched" "Detected in some" 10 "Proximal enterocytes: 5965.8" "Group enriched" "Detected in some" 9 "colorectal cancer: 3.2;pancreatic cancer: 1.6;stomach cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "basophil: 1.6;neutrophil: 4.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RPMI-8226: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA034607, CAB047325, CAB047326" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 61000 "Cluster 1: Neutrophils - Mixed function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "Plasma membrane" "CAB047325: , CAB047326: , HPA034607: AB_10601317" "unprognostic (3.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (4.58e-1)" "unprognostic (1.51e-2)" "unprognostic (2.61e-2)" "unprognostic (1.69e-4)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" 0.2 0.1 0.1 3.1 0.1 0.9 0.0 0.6 0.2 0.0 0.4 28.2 291.0 0.3 0.1 0.1 0.2 0.1 0.6 0.2 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.2 0.3 0.0 0.0 0.1 0.4 550.0 1.9 0.0 0.1 0.7 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.3 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.0 1.6 0.4 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.2 4.2 0.4 0.1 0.3 0.3 0.0 0.1 0.1 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 1.8 0.0 0.0 0.0 242.0 0.0 0.0 0.0 1.4 0.1 0.1 1.2 0.0 0.0 0.2 0.1 0.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 570.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 383.1 0.0 0.0 0.0 5965.8 17.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 222.5 0.0 FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adipose tissue: 3787.4;breast: 2195.7" "Cell type enriched" "Detected in many" 17 "Adipocytes: 24359.7" "Group enriched" "Detected in all" 7 "breast cancer: 42.1;cervical cancer: 141.7;head and neck cancer: 133.8;urothelial cancer: 65.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 171 "ASC diff: 4051.5;RT4: 2107.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002188, CAB024961" Enhanced NA NA 22000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB024961: , HPA002188: AB_1078822" "unprognostic (4.81e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-3)" "unprognostic (2.63e-2)" "unprognostic (2.58e-1)" "unprognostic (8.70e-3)" "unprognostic (1.78e-3)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" "unprognostic (8.76e-2)" "unprognostic (1.13e-3)" "unprognostic (4.48e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-1)" 3787.4 42.2 0.8 46.7 1.1 2.8 2195.7 0.9 1.6 9.9 34.8 52.9 2.8 4.6 0.6 15.1 10.9 68.1 121.8 1.2 0.8 7.0 5.1 113.5 13.6 0.8 0.8 4.2 16.6 59.1 1.4 186.9 0.8 4.3 33.5 2.6 58.8 5.0 66.7 65.2 44.7 14.2 0.7 6.7 26.5 1.1 3.8 29.8 83.0 166.7 2.0 242.7 18.9 0.9 0.0 0.0 0.0 0.0 4051.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 17.9 0.0 0.1 1.3 0.0 0.4 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.8 1.2 0.1 3.0 0.0 9.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 2107.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.2 5.7 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 1.6 1.2 0.8 0.8 0.8 0.8 0.7 3.8 0.9 24359.7 35.3 64.3 0.0 19.4 14.4 1.1 0.9 4.6 0.5 71.7 196.2 42.1 0.0 26.7 0.0 0.0 0.5 73.6 0.0 0.0 0.2 1.6 0.4 8.8 1132.7 0.0 0.0 0.0 5.6 0.7 53.1 1.1 0.2 27.8 0.1 23.2 0.4 114.2 0.0 0.0 0.0 0.0 50.4 15.7 10.9 1.5 192.7 16.0 0.0 0.6 0.9 0.0 0.0 0.0 0.2 2.2 1.2 2.7 0.5 0.0 0.3 21.9 2.4 716.6 62.2 1364.8 0.0 0.1 1.2 13.9 0.7 18.7 2.3 0.0 55.3 FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 3691.0;vagina: 2600.3" "Cell type enhanced" "Detected in all" "Adipocytes: 2511.2;Alveolar cells type 2: 1891.0;Hofbauer cells: 2385.2;Squamous epithelial cells: 9211.0" "Group enriched" "Detected in all" 4 "cervical cancer: 268.3;head and neck cancer: 288.8;urothelial cancer: 73.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 1167.2;MOLT-4: 1213.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 14000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: AB_2681654" "unprognostic (8.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.54e-2)" "unprognostic (9.04e-2)" "unprognostic (1.33e-3)" "unprognostic (1.37e-1)" "unprognostic (1.95e-3)" "unprognostic (4.03e-3)" "unprognostic (2.71e-1)" "unprognostic (3.13e-1)" "unprognostic (6.16e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (4.69e-10)" "unprognostic (1.99e-1)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" 379.8 15.5 107.9 137.8 112.9 111.8 241.8 112.3 146.5 1340.4 307.4 256.7 83.3 62.7 4.8 3691.0 22.4 87.7 343.4 116.6 130.7 34.0 27.5 272.5 191.4 162.8 120.5 12.1 73.1 443.0 32.7 338.8 155.7 22.9 210.6 33.3 514.9 17.1 119.1 692.7 122.3 52.4 133.1 127.4 181.2 45.1 118.2 137.6 74.9 306.1 292.9 362.3 2600.3 138.9 76.9 215.9 133.1 0.3 615.7 59.0 0.3 158.0 8.9 123.2 153.3 2.2 100.3 1167.2 86.7 38.3 1.1 69.2 328.9 254.8 103.7 597.6 603.2 449.0 136.2 345.0 54.2 421.6 107.9 45.0 507.0 146.8 306.1 121.3 708.9 328.6 125.9 124.1 73.7 69.3 1213.7 199.9 170.5 785.1 732.1 526.0 0.4 127.7 198.9 951.4 514.4 190.7 74.1 24.7 61.0 230.2 1.2 201.6 97.0 0.1 331.3 1.6 1.4 155.6 70.1 902.2 52.2 396.8 184.9 8.1 14.3 0.9 6.1 16.6 9.3 17.2 6.9 13.7 55.9 10.4 3.1 11.9 5.2 22.3 5.5 54.8 9.8 13.4 107.9 112.9 112.3 146.5 116.6 130.7 162.8 120.5 155.7 133.1 118.2 138.9 2511.2 288.4 1891.0 30.7 93.0 121.0 90.0 881.2 727.3 23.7 22.3 48.6 5.7 2.8 649.8 22.0 45.9 28.0 97.5 420.3 3.9 35.4 29.5 55.7 579.5 662.2 197.2 74.4 7.7 23.8 272.4 140.6 278.8 29.6 55.8 70.1 35.3 1.4 2385.2 21.9 10.9 216.3 175.0 182.2 764.3 46.0 6.2 405.5 206.3 4.7 697.1 273.0 15.5 6.0 16.3 43.3 561.0 5.3 132.9 71.3 10.4 2.3 115.7 43.5 361.6 140.0 336.8 179.4 182.5 9211.0 168.6 27.0 102.3 68.8 419.2 232.6 FADD "GIG3, MORT1" ENSG00000168040 "Fas associated via death domain" Q13158 11 70203296-70207390 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 75.0;Ductal cells: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 331.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001464, CAB010209" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Cytosol" "CAB010209: AB_2100622, HPA001464: AB_1848348" "unprognostic (2.08e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (6.91e-2)" "unprognostic (9.51e-2)" "unprognostic (3.89e-1)" "prognostic unfavorable (8.22e-5)" "unprognostic (7.25e-3)" "prognostic unfavorable (2.21e-5)" "unprognostic (1.16e-1)" "unprognostic (1.06e-1)" "unprognostic (2.45e-3)" "unprognostic (2.78e-3)" "unprognostic (1.29e-1)" "unprognostic (2.04e-2)" "unprognostic (2.07e-1)" "prognostic favorable (3.45e-4)" "unprognostic (7.29e-2)" 9.8 13.8 10.6 14.0 10.5 8.8 13.6 10.9 10.1 13.1 10.6 14.8 14.1 12.6 17.6 14.3 13.2 12.1 8.4 9.9 10.8 14.2 16.0 10.6 16.9 12.6 10.8 12.5 8.2 9.1 6.4 15.3 11.6 9.2 12.8 4.0 11.3 13.4 10.9 12.5 13.9 10.3 11.2 13.2 14.8 5.7 11.4 20.3 11.3 9.0 16.9 11.4 9.2 11.3 331.2 54.7 26.6 24.3 31.6 25.4 23.8 55.3 43.6 47.5 31.6 47.1 52.3 48.7 51.9 37.1 44.8 47.7 26.3 49.3 36.8 45.7 28.8 22.3 30.6 24.3 28.5 28.0 28.4 25.4 34.5 51.4 64.7 38.1 45.3 26.7 37.0 24.4 42.1 48.5 34.4 49.5 42.1 75.1 89.1 26.3 64.3 47.0 46.8 24.1 23.5 22.3 41.0 38.0 117.1 30.3 41.3 30.7 51.0 36.6 35.7 56.7 53.9 33.8 27.8 28.6 53.2 28.0 52.6 37.1 36.2 28.2 41.7 38.4 47.5 38.7 44.1 48.9 37.1 33.9 44.6 40.7 88.6 37.7 45.3 33.7 45.7 36.1 10.6 10.5 10.9 10.1 9.9 10.8 12.6 10.8 11.6 11.2 11.4 11.3 7.8 0.0 5.3 0.7 12.1 11.9 14.8 18.1 6.2 6.8 14.0 15.7 0.1 14.3 7.7 18.4 0.0 75.0 9.3 22.9 21.5 55.9 0.7 7.3 11.7 15.6 2.4 19.8 1.4 34.7 37.3 10.0 12.8 10.6 1.3 13.8 14.6 8.5 31.2 3.3 1.6 14.3 0.0 11.0 8.8 2.4 13.4 10.8 32.0 2.8 20.9 10.0 18.6 0.5 1.4 49.0 15.3 16.6 9.6 11.8 24.5 33.7 5.4 4.1 0.0 5.2 14.5 10.4 14.2 14.4 10.5 30.8 13.3 18.9 17.4 14.4 FAF1 "CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A" ENSG00000185104 "Fas associated factor 1" Q9UNN5 1 50437028-50960267 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 202.4;Excitatory neurons: 296.7;Inhibitory neurons: 278.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 269.9;Oligodendrocytes: 424.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018253, CAB072814" Approved Supported Nucleoplasm NA NA 12000 "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB072814: , HPA018253: AB_1848351" "unprognostic (1.52e-1)" "unprognostic (1.25e-2)" "unprognostic (6.49e-3)" "unprognostic (4.69e-2)" "unprognostic (6.35e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (9.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.01e-3)" "unprognostic (6.42e-3)" 18.2 16.8 21.0 9.2 22.0 21.0 18.5 21.8 27.5 18.9 18.7 23.7 12.4 18.2 11.7 23.1 15.7 8.7 34.9 22.3 22.1 21.5 23.6 14.9 13.1 21.5 21.5 19.9 26.2 23.2 20.6 10.6 22.0 18.5 12.7 19.6 18.1 16.3 67.9 28.1 16.4 13.4 21.8 14.0 18.2 47.8 21.2 22.2 18.3 37.6 14.1 21.4 18.7 25.9 37.4 27.1 23.1 39.3 22.4 21.1 33.9 35.5 32.1 53.9 48.8 30.4 26.0 59.9 25.7 30.5 47.5 27.2 37.3 33.1 45.9 40.1 33.5 49.9 33.5 31.6 36.4 54.3 28.5 19.8 29.4 57.0 69.4 27.8 29.5 44.5 58.9 0.2 28.1 15.0 56.6 43.0 30.6 49.3 19.2 52.1 50.7 0.0 54.9 33.1 0.3 28.6 32.3 64.9 56.4 32.0 20.4 64.1 18.2 30.4 37.3 37.8 0.2 45.1 50.6 69.3 0.0 77.6 35.7 1.1 2.1 4.9 4.0 2.7 5.5 2.5 3.6 4.0 3.6 4.2 4.3 2.8 0.7 4.3 3.5 2.9 6.1 1.6 21.0 22.0 21.8 27.5 22.3 22.1 21.5 21.5 22.0 21.8 21.2 25.9 17.9 6.4 18.2 202.4 26.9 21.4 38.5 27.8 33.6 19.9 16.9 16.9 43.9 11.5 27.2 16.5 27.1 14.2 18.0 13.1 29.4 8.8 75.1 15.1 15.6 14.2 11.4 44.6 296.7 11.6 28.2 16.0 29.0 16.9 5.7 19.2 10.4 18.2 11.4 16.8 278.9 17.8 6.1 13.6 18.0 117.2 11.1 15.4 16.0 177.1 8.9 20.0 15.5 269.9 424.4 8.5 9.7 10.9 35.4 18.3 20.0 28.3 32.7 33.0 6.6 26.2 20.3 36.9 15.6 37.9 28.1 15.3 27.9 19.6 21.6 34.1 FAM166A ENSG00000188163 "Family with sequence similarity 166 member A" Q6J272 9 137243584-137247770 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 60.8" "Group enriched" "Detected in some" 121 "Early spermatids: 626.7;Late spermatids: 1323.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA023307 Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA023307: AB_1848930" "unprognostic (2.22e-1)" "unprognostic (8.39e-2)" "unprognostic (1.01e-3)" "unprognostic (1.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (9.83e-2)" "unprognostic (2.18e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (2.67e-4)" "unprognostic (7.81e-2)" "unprognostic (1.77e-3)" "unprognostic (1.83e-1)" "unprognostic (2.02e-2)" "unprognostic (2.09e-1)" "unprognostic (4.18e-3)" 0.5 0.4 0.0 0.2 0.1 0.1 0.5 0.2 0.2 0.3 0.0 0.2 0.2 0.3 0.7 0.4 0.3 0.0 0.5 0.1 0.1 1.1 1.9 0.2 0.1 0.1 0.1 0.1 0.5 0.0 0.9 0.0 0.1 0.5 0.0 0.4 0.4 0.1 0.2 0.3 0.4 0.0 0.1 0.2 0.3 60.8 0.1 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.4 0.1 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 626.7 0.3 0.1 0.6 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.2 3.8 0.1 0.7 0.8 0.1 0.0 0.2 0.0 0.0 0.3 0.0 1323.3 5.9 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 6.4 0.0 0.2 0.1 0.2 1.6 0.6 0.0 0.3 0.3 8.0 4.8 0.0 0.3 0.3 0.3 0.2 0.0 0.2 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.1;Spermatogonia: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 1.4 1.9 1.7 6.7 1.9 20.2 1.9 2.4 3.3 2.1 1.5 5.5 5.2 1.2 0.8 6.6 2.0 1.2 1.6 1.8 1.2 2.9 6.1 3.4 12.5 1.4 1.1 1.4 1.9 1.4 1.9 4.1 1.5 1.7 6.2 1.0 2.1 0.6 0.7 5.2 5.6 2.1 1.1 6.7 3.6 21.6 1.5 8.1 1.7 0.6 13.5 2.2 2.7 1.9 23.2 34.8 40.8 35.7 2.6 5.2 31.2 28.2 15.3 46.5 19.5 30.6 37.3 56.2 12.9 9.8 15.5 34.7 27.7 21.1 48.8 13.4 46.5 16.6 49.1 63.4 1.7 17.1 17.5 1.7 2.2 37.8 12.0 6.6 14.9 28.0 40.9 16.9 24.6 53.6 34.6 73.7 26.5 31.5 21.3 61.4 32.8 10.3 11.8 21.5 36.3 19.7 41.9 12.3 5.4 23.3 22.4 30.4 11.1 37.0 38.9 20.9 30.0 15.1 19.0 56.3 17.5 37.8 36.1 2.5 7.4 9.9 4.2 8.5 3.0 7.0 2.4 3.7 6.2 4.6 0.6 2.6 9.4 8.2 9.2 0.4 9.2 4.2 1.7 1.9 2.4 3.3 1.8 1.2 1.4 1.1 1.5 1.1 1.5 1.9 1.5 0.0 1.1 0.7 9.6 3.4 1.6 2.6 0.0 8.1 3.0 2.0 2.9 0.0 3.5 16.5 10.4 16.0 12.3 5.1 1.9 2.0 5.9 2.8 3.5 2.1 1.8 20.8 10.0 1.6 9.9 3.3 9.2 3.4 2.5 19.0 5.3 4.7 8.8 3.3 5.7 8.1 2.0 4.1 3.1 4.1 1.5 6.8 0.0 1.0 3.0 1.1 21.6 3.0 1.7 1.9 1.7 0.0 21.1 1.3 6.6 10.4 6.4 7.7 0.0 2.7 3.5 44.1 38.5 3.8 1.8 25.3 9.3 6.8 11.4 2.6 FANCC "FA3, FAC, FACC" ENSG00000158169 "FA complementation group C" Q00597 9 95099054-95426796 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 24.6" "Cell type enhanced" "Detected in many" "Early spermatids: 178.6;Hepatocytes: 42.6;Late spermatids: 87.8;Microglial cells: 49.6;Oligodendrocytes: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 8.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.8" "Cell line enhanced" "Detected in all" "RH-30: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017793, HPA030771" Approved Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB017793: , HPA030771: AB_2673604" "unprognostic (1.48e-2)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (2.63e-1)" "unprognostic (2.14e-1)" "unprognostic (1.32e-2)" "unprognostic (3.41e-3)" "unprognostic (1.26e-2)" "unprognostic (7.45e-3)" "unprognostic (1.37e-1)" "unprognostic (8.00e-3)" "unprognostic (3.19e-2)" "prognostic favorable (6.03e-6)" "unprognostic (2.35e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.71e-2)" 2.6 1.7 1.7 3.1 2.4 3.3 3.4 8.9 2.7 4.1 1.7 4.0 5.5 3.2 1.1 3.5 2.8 3.7 2.7 1.8 2.3 6.8 24.6 4.0 2.7 3.9 2.3 2.3 4.4 1.5 3.5 3.1 3.2 3.5 4.3 2.4 3.0 1.5 3.6 5.9 6.2 2.1 1.7 2.3 3.6 9.5 2.4 4.2 3.1 1.2 2.6 3.0 3.2 3.9 21.5 14.6 18.7 16.9 2.0 5.4 11.7 8.1 5.7 14.1 13.9 16.2 9.3 12.7 6.4 7.2 10.6 25.5 21.1 8.5 8.4 12.9 10.1 9.8 16.6 9.6 2.7 11.6 11.3 4.9 3.8 11.1 5.4 3.9 8.4 10.1 14.9 5.7 10.3 17.1 9.7 5.8 9.6 23.2 8.9 17.3 47.1 7.0 6.4 6.8 26.2 13.1 18.9 7.4 4.2 8.2 6.9 8.6 4.0 13.0 17.1 14.5 14.1 5.9 12.0 6.8 6.6 9.8 15.9 8.8 0.3 0.0 0.9 0.6 0.9 0.6 0.4 0.9 0.3 0.6 0.7 0.7 0.1 0.1 1.3 0.9 0.4 0.5 1.7 2.4 8.9 2.7 1.8 2.3 3.9 2.3 3.2 1.7 2.4 3.9 3.0 3.2 2.2 9.4 2.2 2.5 2.7 1.2 2.8 6.1 3.5 3.7 1.9 5.7 2.3 0.0 4.2 3.0 2.7 3.3 1.9 4.4 178.6 3.5 5.5 4.3 0.0 3.0 22.1 4.1 5.0 3.3 2.0 4.7 5.7 3.9 5.0 42.6 2.0 10.1 13.8 4.0 0.0 3.5 1.3 87.8 6.5 1.6 1.8 49.6 2.8 2.1 1.0 32.2 48.9 3.1 1.0 2.2 4.4 3.0 5.6 8.9 1.0 4.5 0.0 4.1 2.3 19.4 13.2 4.0 2.7 2.3 2.1 4.5 4.7 2.5 FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026414-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Spermatocytes: 62.5;Spermatogonia: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 120.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB016117: AB_2278211, HPA063742: AB_2685110" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "unprognostic (6.21e-2)" "unprognostic (1.12e-2)" "unprognostic (2.92e-1)" "unprognostic (3.36e-2)" "unprognostic (1.08e-5)" "unprognostic (2.96e-2)" "unprognostic (1.59e-3)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.23e-2)" "unprognostic (9.14e-2)" "unprognostic (4.41e-10)" "unprognostic (9.11e-3)" "unprognostic (3.99e-1)" "unprognostic (7.76e-2)" "unprognostic (2.89e-2)" 1.1 0.7 2.7 7.7 2.1 17.8 3.4 1.6 5.3 1.5 1.1 4.0 3.2 2.0 0.7 2.5 2.6 2.0 0.5 3.4 1.6 0.9 1.1 1.9 12.2 3.9 1.4 3.6 0.8 0.8 0.5 4.7 3.0 1.9 6.4 3.1 4.9 1.0 4.8 4.5 4.0 2.0 2.4 6.4 3.5 11.8 2.3 9.8 1.9 0.4 13.0 2.3 1.3 5.1 24.1 25.4 46.5 13.2 2.4 3.5 120.7 22.0 9.8 31.3 25.4 18.8 23.0 46.7 9.8 7.0 25.1 20.2 48.8 16.7 31.0 22.6 33.0 63.6 39.6 17.9 0.4 48.1 37.9 1.2 2.6 34.1 18.4 4.2 18.4 39.3 39.6 51.6 23.1 27.2 40.6 17.9 56.1 18.1 17.6 43.4 37.7 32.5 10.3 26.7 13.0 25.3 26.4 20.1 8.3 33.5 31.0 29.4 10.6 24.6 28.4 15.1 31.5 21.7 46.4 77.2 14.1 47.7 43.2 2.7 0.6 1.9 0.6 0.5 0.6 2.4 0.9 0.5 0.4 3.2 1.1 0.9 1.5 1.0 1.4 1.8 1.5 0.5 2.7 2.1 1.6 5.3 3.4 1.6 3.9 1.4 3.0 2.4 2.3 5.1 0.7 0.0 0.5 0.7 12.5 4.6 3.5 2.9 2.8 3.1 4.5 2.7 2.0 1.5 1.9 1.8 10.4 12.7 5.6 3.1 0.0 1.9 5.9 2.6 1.5 2.1 1.2 25.2 3.0 3.5 15.2 2.6 2.0 3.4 1.3 11.8 3.3 1.5 5.7 0.0 2.6 3.2 6.1 3.8 7.0 8.0 2.1 3.7 3.6 1.9 4.9 0.6 1.0 1.5 2.4 1.8 3.6 1.5 8.1 2.2 0.5 0.7 2.0 5.6 19.7 2.6 2.1 62.5 30.2 4.1 2.7 7.0 5.2 1.6 7.6 3.1 FANCE "FACE, FAE" ENSG00000112039 "FA complementation group E" Q9HB96 6 35452338-35467102 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 22.1;Extravillous trophoblasts: 104.8;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB014893 Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB014893: " "unprognostic (2.66e-1)" "unprognostic (8.01e-3)" "unprognostic (7.73e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.80e-3)" "prognostic unfavorable (2.08e-9)" "unprognostic (8.90e-2)" "unprognostic (5.70e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.14e-2)" 4.6 1.5 2.6 3.2 2.5 5.8 5.0 2.8 3.1 7.1 2.0 3.1 2.1 3.7 3.4 8.6 4.8 1.5 3.3 2.3 2.9 2.1 1.3 4.1 4.5 2.7 2.6 7.8 3.5 4.0 3.1 9.3 2.6 3.8 3.0 1.8 4.3 2.7 11.0 13.8 3.5 3.1 2.4 3.8 3.4 8.7 2.7 2.6 3.0 3.1 5.7 4.0 7.7 2.7 9.9 4.2 12.8 27.6 9.2 15.9 34.6 11.4 9.6 14.8 12.1 11.1 5.3 33.0 7.5 6.7 11.2 7.2 13.7 9.8 13.9 11.0 11.9 23.8 11.7 6.8 4.8 12.6 8.2 10.1 28.6 17.7 27.7 3.9 8.7 12.6 21.3 11.6 12.2 11.4 5.8 16.6 4.7 10.6 7.0 18.8 12.3 12.1 3.1 10.0 12.1 11.4 6.4 9.1 10.0 11.9 8.8 43.7 5.6 16.7 14.5 10.9 18.1 7.4 29.3 11.6 3.9 24.3 16.8 0.0 0.2 0.2 0.4 0.1 0.7 0.1 0.6 0.9 0.1 0.5 0.3 0.3 0.0 0.5 0.1 0.4 0.3 0.2 2.6 2.5 2.8 3.1 2.3 2.9 2.7 2.6 2.6 2.4 2.7 2.7 7.0 6.4 0.0 1.0 2.4 8.8 4.1 4.7 1.8 1.1 2.0 2.8 2.7 0.0 1.6 0.0 0.0 22.1 2.0 1.6 0.0 1.7 0.3 1.9 2.4 3.7 1.2 2.5 0.4 0.8 104.8 2.8 1.1 3.4 0.0 5.2 1.4 0.7 6.0 0.0 0.9 3.6 0.0 0.8 1.3 0.6 1.5 1.4 1.8 2.8 0.5 1.9 1.0 0.5 1.0 1.1 0.4 0.7 3.1 5.8 1.1 0.3 0.1 2.0 0.0 4.0 3.4 8.2 13.2 4.6 7.1 46.7 2.2 3.4 4.4 3.5 FANCF FAF ENSG00000183161 "FA complementation group F" Q9NPI8 11 22622533-22625823 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Distal tubular cells: 45.0;Early spermatids: 168.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008899 Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA008899: " "unprognostic (1.16e-2)" "unprognostic (4.10e-2)" "unprognostic (2.33e-2)" "unprognostic (1.37e-2)" "unprognostic (4.55e-2)" "unprognostic (8.84e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (4.29e-2)" "unprognostic (1.11e-1)" "unprognostic (2.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.67e-1)" "unprognostic (2.29e-1)" "unprognostic (3.73e-2)" "unprognostic (1.81e-1)" "unprognostic (9.14e-2)" "unprognostic (7.64e-3)" 2.1 3.8 3.8 5.6 3.8 2.8 5.2 4.1 3.9 4.9 6.1 5.6 7.9 3.9 8.5 2.8 8.9 3.2 3.6 3.5 4.2 5.0 4.2 3.4 8.2 4.2 4.3 6.1 8.1 4.9 3.7 3.0 3.9 4.6 5.9 5.1 6.1 4.8 1.2 5.1 7.6 2.5 4.1 6.3 7.1 4.9 4.6 9.3 5.6 1.1 7.7 3.5 2.1 4.5 2.3 6.7 8.6 9.5 4.5 5.4 3.5 4.3 5.3 5.0 5.5 4.3 3.5 11.3 1.2 4.5 8.9 9.6 7.2 7.5 2.5 18.5 3.3 4.3 2.7 7.0 5.2 8.0 4.6 5.2 14.1 1.7 7.7 8.5 8.1 15.9 10.9 13.8 3.2 7.0 20.4 7.5 9.8 19.2 8.4 17.0 4.1 12.8 9.7 8.7 32.0 15.1 2.4 7.7 7.8 9.2 15.5 7.1 5.7 5.0 5.1 9.3 6.4 8.0 11.0 3.4 8.1 3.2 11.8 12.3 7.6 16.8 15.3 8.1 18.0 16.1 14.3 14.9 9.2 20.9 19.3 16.2 1.1 15.0 8.7 13.5 10.7 10.6 3.8 3.8 4.1 3.9 3.5 4.2 4.2 4.3 3.9 4.1 4.6 4.5 4.7 3.2 2.2 2.3 13.9 3.3 6.2 8.8 6.8 15.2 7.1 6.0 5.7 18.6 6.3 3.7 10.4 11.6 15.3 10.2 45.0 18.8 168.1 14.1 6.8 6.3 3.5 8.0 2.6 18.7 7.5 5.4 10.7 6.8 2.5 9.6 6.4 10.7 6.9 16.8 3.3 16.5 10.2 6.9 2.6 25.5 9.6 6.7 5.4 5.6 11.3 13.1 22.6 0.5 6.2 10.7 10.3 9.8 7.1 5.6 13.2 22.5 24.4 18.0 6.6 3.2 5.3 23.1 16.7 10.1 2.3 2.3 11.2 11.1 15.8 2.4 FANCG "FAG, XRCC9" ENSG00000221829 "FA complementation group G" O15287 9 35073835-35079942 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 20.6;Spermatogonia: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008105, HPA045335" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" Nucleoli "CAB008105: AB_2231542, HPA045335: AB_2679292" "unprognostic (9.41e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (8.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.14e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" 3.4 3.1 2.8 5.1 2.8 12.4 4.5 3.6 3.8 5.1 2.1 4.3 4.9 4.2 2.3 5.9 5.8 3.3 1.9 2.7 2.7 3.9 2.9 3.3 7.7 2.8 2.7 6.2 6.3 4.7 3.0 4.5 2.7 3.9 4.0 2.4 4.3 4.1 2.3 6.5 4.6 4.5 2.5 5.5 4.1 6.4 2.7 12.2 4.0 1.7 6.9 3.5 4.6 3.4 34.7 40.7 30.4 28.3 6.4 10.2 25.0 23.6 16.3 44.9 42.5 20.1 21.2 33.4 15.8 7.7 33.1 20.5 25.3 22.0 17.6 38.7 14.8 24.5 45.5 13.2 1.8 24.5 26.9 8.1 4.1 39.5 18.2 8.0 23.8 40.7 15.7 44.3 23.5 31.5 43.2 34.5 32.5 26.4 30.1 43.8 35.2 23.1 10.9 14.6 14.4 26.1 15.7 22.3 8.3 13.4 28.4 17.2 13.4 21.0 42.8 28.3 33.1 12.4 24.0 20.6 19.2 18.5 30.1 10.5 0.7 6.7 6.1 2.2 5.3 5.6 4.8 4.6 1.9 5.4 3.6 3.8 1.1 7.8 2.0 4.2 8.2 3.1 2.8 2.8 3.6 3.8 2.7 2.7 2.8 2.7 2.7 2.5 2.7 3.4 3.2 3.2 4.6 6.8 4.9 4.5 6.1 3.9 10.2 4.7 5.9 5.0 1.5 2.8 3.3 3.7 4.2 15.0 4.1 3.0 3.9 4.9 0.4 2.3 3.8 4.4 1.8 11.6 3.0 2.3 20.6 5.1 1.5 3.6 14.0 10.3 4.2 1.1 7.7 5.0 3.3 4.1 2.0 1.3 4.7 0.6 3.4 2.3 3.6 1.0 2.8 4.0 3.1 0.5 4.1 1.9 2.4 4.1 14.1 4.4 3.5 2.3 1.3 3.1 0.0 3.0 3.9 14.7 20.7 8.5 2.6 6.6 4.9 2.8 6.7 5.2 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 14 "dendritic cells: 43.4;NK-cells: 79.3;T-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" 0.3 0.8 0.1 1.0 0.2 2.8 0.6 0.1 0.2 0.4 0.1 0.8 1.9 0.5 0.7 0.3 0.3 1.1 0.3 0.2 0.1 0.3 1.1 2.0 5.7 0.3 0.2 0.3 0.1 0.0 0.1 0.2 0.2 0.5 0.9 0.0 0.9 0.3 0.1 0.4 1.4 0.3 0.0 4.1 1.5 0.2 0.1 0.6 0.2 0.0 1.8 0.8 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 58.1 0.2 35.5 0.0 11.5 31.4 0.1 0.0 2.2 25.0 1.9 41.5 0.1 0.0 0.2 14.9 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.4 0.4 0.0 2.5 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 43.4 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.6 1.8 0.0 0.9 0.0 79.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 28.8 0.0 0.0 0.1 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 119.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 285.7;LHCN-M2: 206.7" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" NA NA 4600000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" 20.1 1.3 14.5 7.2 20.2 0.8 21.9 31.1 12.4 20.0 119.2 35.0 25.9 23.4 16.0 13.3 9.8 23.5 24.8 14.3 27.0 22.1 10.0 12.9 2.4 40.1 42.3 10.4 12.6 11.4 9.7 17.0 24.4 21.4 31.4 3.4 18.7 24.2 3.5 17.5 24.2 25.7 22.1 2.2 16.8 9.7 22.2 6.0 14.6 3.9 4.4 32.0 11.0 22.0 22.2 83.5 80.9 0.3 79.1 94.5 19.9 110.9 181.9 52.8 33.5 50.0 49.0 0.0 26.0 285.7 34.1 40.4 32.0 136.7 71.6 0.2 13.2 0.0 30.5 50.8 39.4 37.3 29.2 34.5 48.4 98.7 63.5 72.4 1.1 44.8 0.6 0.0 206.7 27.1 66.2 0.1 18.1 42.2 13.9 0.3 22.3 1.8 79.2 79.0 8.6 32.3 19.2 32.2 12.7 54.9 0.3 13.3 23.8 149.8 57.9 2.0 69.8 0.4 0.2 0.5 34.1 0.1 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 20.2 31.1 12.4 14.3 27.0 40.1 42.3 24.4 22.1 22.2 22.0 6.1 16.0 6.7 55.2 0.3 85.0 27.2 115.4 27.3 5.2 26.5 27.6 27.6 38.6 40.7 53.3 0.0 1.6 0.2 71.2 5.9 25.2 0.7 25.7 17.2 5.0 14.5 0.0 5.8 26.5 3.6 28.8 54.0 29.6 16.5 75.0 1.1 26.1 0.4 0.0 30.3 56.4 18.3 0.8 7.3 0.9 14.6 1.7 12.4 5.6 0.0 4.5 0.0 14.1 12.4 30.3 30.0 37.2 0.2 55.8 78.2 26.7 37.0 0.4 39.5 23.1 65.1 1.5 10.4 10.2 46.9 1.6 1.9 11.7 45.1 38.9 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FBN2 "CCA, DA9" ENSG00000138829 "Fibrillin 2" P35556 5 128257909-128659185 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 81.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 298.1;Syncytiotrophoblasts: 163.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 5 "monocytes: 2.2" "Cell line enhanced" "Detected in many" "HHSteC: 134.1;HSkMC: 94.3;hTERT-HME1: 215.2;HUVEC TERT2: 122.3" "Region enhanced" "Detected in single" "olfactory bulb: 2.0" "Low region specificity" "Detected in many" "HPA012853, CAB026401" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 11000000 "Cluster 14: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Nucleoplasm "CAB026401: , HPA012853: AB_1848588" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (7.29e-3)" "unprognostic (1.79e-3)" "unprognostic (6.74e-2)" "unprognostic (2.33e-1)" "unprognostic (4.92e-3)" "unprognostic (9.41e-2)" "unprognostic (1.06e-2)" "unprognostic (4.66e-1)" "unprognostic (1.12e-1)" "unprognostic (8.69e-2)" "unprognostic (8.60e-5)" "unprognostic (1.04e-2)" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (7.41e-5)" 0.1 5.1 0.4 0.8 0.5 3.1 0.2 0.0 0.3 2.2 3.0 0.8 0.3 1.7 0.1 0.1 0.4 0.3 5.5 0.2 0.6 0.1 0.1 0.2 0.5 1.1 1.9 0.5 0.2 0.0 0.8 81.9 0.5 0.8 1.2 0.9 0.3 0.4 0.2 0.2 0.4 1.3 0.5 0.4 0.8 7.4 0.8 0.2 0.5 0.4 0.9 0.5 0.7 0.3 0.0 16.4 58.2 0.0 9.4 16.6 11.8 62.8 0.0 56.0 41.8 0.2 0.0 0.0 0.1 85.5 0.0 9.2 37.6 9.8 52.7 0.1 13.8 0.0 27.3 0.2 134.1 8.4 0.0 94.3 5.3 24.1 215.2 17.9 122.3 0.0 0.0 0.0 35.8 0.1 0.0 3.4 24.5 0.0 18.2 19.2 18.1 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.6 48.0 0.0 18.7 0.0 22.1 41.9 66.8 0.3 0.0 0.0 0.0 6.9 0.0 23.8 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.2 0.6 1.1 1.9 0.5 0.5 0.8 0.3 0.1 0.0 0.5 1.6 0.2 0.0 0.1 1.2 0.6 0.0 0.3 0.3 12.7 0.0 1.4 0.0 0.0 298.1 0.0 0.0 0.0 0.3 3.8 10.0 3.9 1.0 0.0 0.0 1.1 0.0 24.3 8.8 0.0 4.7 0.0 0.1 0.0 0.0 34.0 0.0 50.5 0.0 0.0 10.7 0.4 7.2 1.2 2.7 1.8 1.9 6.2 3.8 0.0 17.6 1.5 0.1 0.0 2.2 0.0 2.0 0.0 0.2 1.6 0.1 6.6 0.1 3.5 10.7 3.5 0.1 0.4 163.5 0.1 8.4 0.1 0.1 FBXO11 "FBX11, UBR6" ENSG00000138081 "F-box protein 11" Q86XK2 2 47789316-47906498 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002690 Supported Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "HPA002690: AB_1848448" "unprognostic (1.18e-1)" "unprognostic (8.65e-3)" "unprognostic (3.93e-2)" "unprognostic (2.05e-2)" "unprognostic (7.92e-2)" "unprognostic (1.42e-1)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (2.55e-2)" "unprognostic (9.82e-2)" "unprognostic (5.77e-2)" "unprognostic (2.33e-2)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (3.71e-1)" "unprognostic (2.19e-1)" "unprognostic (3.20e-2)" 27.9 19.6 24.5 19.1 25.9 32.2 20.9 32.7 28.7 21.1 21.0 19.7 16.8 33.1 24.8 18.7 22.2 20.9 22.8 26.5 25.6 21.7 26.8 22.5 25.7 22.8 23.1 34.4 19.6 30.2 17.5 23.0 24.0 22.7 20.1 33.3 16.5 20.4 28.3 19.1 17.3 29.7 22.9 24.2 19.1 41.0 25.9 22.5 26.1 28.7 27.7 22.1 16.9 25.2 52.8 26.9 62.9 53.9 42.6 40.2 37.2 36.0 48.6 32.6 31.9 22.9 25.9 32.8 45.4 50.2 40.5 25.6 42.5 37.1 47.9 22.3 21.5 31.6 21.3 36.6 41.0 33.5 32.1 39.3 41.7 28.8 48.2 51.9 42.1 16.6 31.3 33.9 40.4 25.5 31.7 32.8 38.2 34.7 26.2 40.9 58.3 25.5 47.1 42.5 44.1 52.3 34.2 31.5 54.6 46.4 14.7 27.9 46.4 40.2 37.2 27.5 40.0 28.9 16.5 60.9 27.4 30.8 42.1 4.3 1.1 2.1 1.5 1.2 1.6 2.1 1.4 1.7 1.4 1.5 2.6 1.7 2.6 2.2 1.1 2.0 1.6 1.1 24.5 25.9 32.7 28.7 26.5 25.6 22.8 23.1 24.0 22.9 25.9 25.2 40.6 16.0 39.0 100.9 34.1 67.0 44.4 22.0 24.5 45.1 22.3 15.1 11.0 15.7 24.9 18.4 33.3 19.6 37.8 24.7 11.7 17.2 34.4 38.6 40.3 39.4 23.9 17.1 151.4 15.2 16.0 37.0 23.4 48.6 29.1 37.3 33.2 20.0 25.5 55.5 134.8 17.1 24.4 40.1 81.4 40.4 30.1 51.8 35.6 137.7 30.9 30.2 25.7 138.7 143.8 25.8 17.1 39.9 36.3 44.3 17.3 14.6 37.4 42.5 19.7 42.3 34.6 86.6 50.7 24.2 59.0 36.0 35.6 33.4 19.5 65.1 FBXO6 "FBG2, FBS2, FBX6, Fbx6b" ENSG00000116663 "F-box protein 6" Q9NRD1 1 11664200-11674354 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.6;Late spermatids: 117.8;NK-cells: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051175 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA051175: AB_2681372" "unprognostic (3.23e-3)" "unprognostic (2.58e-2)" "unprognostic (8.27e-2)" "unprognostic (2.69e-3)" "unprognostic (1.11e-1)" "unprognostic (6.64e-2)" "unprognostic (9.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.18e-1)" "prognostic favorable (7.12e-4)" "unprognostic (1.47e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (2.65e-2)" "unprognostic (2.11e-1)" "unprognostic (5.23e-2)" "prognostic favorable (5.90e-4)" 6.5 10.7 9.9 11.8 10.1 20.3 6.7 10.3 12.4 7.6 8.2 7.6 13.5 5.0 6.0 10.3 14.1 8.7 10.0 9.8 11.5 7.8 18.5 11.4 18.3 9.9 10.5 5.9 13.8 13.5 6.1 2.6 9.7 8.7 6.8 3.6 13.0 8.4 18.7 9.5 8.2 7.4 10.0 13.0 9.8 10.8 12.6 7.1 6.7 14.5 11.1 9.5 7.0 9.8 10.0 7.3 0.8 0.4 2.1 6.8 4.5 4.2 6.6 20.1 9.2 7.6 8.3 0.3 18.7 7.0 5.5 0.2 6.8 7.5 1.5 26.3 1.0 0.2 1.0 7.7 15.4 9.4 0.1 7.9 15.8 2.5 6.3 4.3 2.6 10.3 22.7 18.7 1.8 19.1 3.4 7.8 0.8 10.2 9.7 2.3 0.1 0.7 6.9 1.4 1.6 2.0 9.3 10.9 14.3 1.8 10.5 10.2 2.0 1.0 0.8 2.7 0.3 10.0 7.5 3.9 1.2 21.6 1.8 17.1 49.5 65.0 47.0 75.0 25.4 15.3 12.0 31.3 66.5 15.0 7.1 23.7 41.4 41.4 91.0 27.3 13.1 36.6 9.9 10.1 10.3 12.4 9.8 11.5 9.9 10.5 9.7 10.0 12.6 9.8 6.0 6.4 6.9 3.3 8.4 7.0 6.6 14.6 4.0 4.3 8.3 7.4 6.8 2.8 15.0 9.2 2.1 1.1 19.5 10.7 0.0 14.5 60.6 15.7 4.5 4.0 4.9 1.7 1.8 38.5 9.2 7.8 8.6 5.3 3.8 2.2 8.2 19.9 26.2 5.0 2.6 8.3 8.2 15.4 34.7 117.8 8.1 18.3 7.2 1.0 37.8 9.0 60.8 0.0 1.3 13.0 10.8 11.3 12.2 11.3 14.3 15.6 36.5 7.8 0.0 3.3 4.0 4.0 11.9 7.3 9.8 1.8 16.0 1.8 9.2 11.2 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 201.8;Excitatory neurons: 529.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 14.2 9.5 37.9 15.0 43.1 19.8 14.2 54.3 66.9 8.7 6.7 9.5 7.8 8.6 24.3 14.3 15.6 9.2 24.7 48.2 23.0 6.7 11.2 11.4 16.1 17.1 20.9 9.1 12.8 7.8 9.2 9.4 18.1 7.8 10.3 18.0 11.8 7.5 26.0 63.1 10.4 9.1 11.8 16.2 13.0 22.8 29.4 14.7 10.3 19.7 20.3 11.9 10.7 47.4 9.8 8.0 19.1 14.2 12.2 9.4 16.2 13.4 12.9 8.5 8.1 15.7 12.0 24.7 3.9 13.7 6.5 5.2 16.9 30.9 12.1 16.2 8.0 11.9 10.7 10.9 12.7 29.2 10.6 14.8 45.7 15.2 24.4 8.4 15.2 20.5 19.2 25.7 10.8 13.7 34.9 10.6 9.7 8.0 6.1 32.2 8.0 5.3 9.8 17.0 12.7 10.2 8.5 11.3 7.5 21.6 6.4 12.6 15.6 11.3 12.6 5.4 8.2 79.0 47.5 24.4 9.4 9.2 8.3 23.5 2.7 1.6 4.0 3.0 2.7 2.8 3.1 2.7 1.6 1.8 3.4 2.5 4.8 7.1 2.2 2.1 2.9 1.3 37.9 43.1 54.3 66.9 48.2 23.0 17.1 20.9 18.1 11.8 29.4 47.4 29.5 9.6 22.9 80.0 48.1 201.8 36.5 29.9 120.1 74.9 32.1 30.9 61.8 12.8 15.1 9.2 31.3 10.9 54.7 22.2 3.9 14.3 17.4 37.7 37.3 36.1 14.5 30.1 529.6 13.5 39.9 27.2 21.4 61.6 15.8 19.1 17.9 18.3 10.5 11.8 186.5 16.4 32.6 18.8 47.0 10.2 15.2 33.7 28.4 172.4 28.0 37.0 35.0 102.5 99.8 18.7 18.2 11.3 174.5 36.3 8.9 7.5 11.9 41.4 13.1 33.2 25.5 74.1 87.2 57.0 174.9 31.2 46.2 18.7 14.9 70.5 FCER2 "CD23, CD23A, CLEC4J, FCE2" ENSG00000104921 "Fc fragment of IgE receptor II" P06734 19 7688758-7702146 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgE-binding protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 42.2" "Cell type enriched" "Detected in some" 16 "B-cells: 157.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in many" 24 "memory B-cell: 200.9;naive B-cell: 496.2" "Lineage enriched" "Detected in many" 34 "B-cells: 496.2" "Cell line enriched" "Detected in some" 14 "HDLM-2: 449.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002624, HPA008928, HPA067430" Enhanced "Secreted to blood" NA NA 240000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "CAB002624: , HPA008928: AB_1846285, HPA067430: " "unprognostic (3.20e-4)" "unprognostic (1.87e-3)" "unprognostic (1.95e-2)" "unprognostic (2.44e-2)" "unprognostic (4.77e-2)" "unprognostic (1.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.89e-3)" "unprognostic (2.71e-1)" "unprognostic (1.88e-1)" "unprognostic (2.04e-2)" "unprognostic (8.55e-2)" "unprognostic (2.46e-4)" "unprognostic (2.99e-1)" "unprognostic (1.80e-1)" "unprognostic (4.89e-2)" "unprognostic (5.17e-2)" 4.8 0.1 0.0 17.4 0.0 5.2 1.2 0.2 1.3 0.4 0.0 1.8 2.8 0.1 0.1 0.4 0.3 1.1 0.5 0.3 0.0 0.3 0.5 0.6 39.5 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.1 1.9 0.0 1.8 0.1 0.3 0.4 9.7 0.2 0.0 38.4 2.2 0.4 0.0 6.3 0.6 0.1 42.2 1.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 449.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 0.1 32.7 0.0 0.5 4.2 0.3 0.0 14.7 0.1 200.9 0.2 0.0 4.4 496.2 0.3 0.1 1.5 0.3 4.4 0.6 0.2 21.6 0.0 0.0 0.2 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 157.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.1 0.0 1.2 0.0 0.1 0.0 0.0 1.3 1.7 0.0 0.0 9.4 1.8 1.0 0.9 0.0 2.1 0.0 0.1 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 1.2 1.2 0.0 0.0 FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 75.0;Hepatic stellate cells: 333.8;Langerhans cells: 244.0;Macrophages: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 24.9;HMC-1: 31.2;NB-4: 7.3;RPMI-8226: 11.7" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" 30.4 7.5 0.9 12.2 1.3 1.7 15.4 1.3 3.3 9.7 4.2 10.3 3.0 2.6 2.8 11.4 4.4 13.0 7.9 0.7 1.1 4.2 42.4 21.7 15.8 4.5 1.1 4.8 4.7 2.8 1.4 398.2 2.2 1.8 11.0 1.1 7.0 2.8 2.2 4.8 16.0 16.6 2.2 25.5 4.9 2.5 1.4 7.4 4.2 13.7 29.6 18.7 3.1 5.8 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 7.3 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.8 0.0 327.2 8.5 26.4 1.4 9.7 0.6 202.8 0.7 1.1 72.4 160.4 0.1 1.4 53.6 0.7 9.5 0.1 0.1 13.0 0.9 1.3 1.3 3.3 0.7 1.1 4.5 1.1 2.2 2.2 1.4 5.8 2.2 0.0 3.9 0.0 75.0 5.4 0.1 0.0 0.0 0.0 0.3 0.9 2.1 2.8 1.3 0.0 0.0 0.2 5.6 0.0 0.0 0.0 4.8 0.0 0.0 49.8 0.0 3.2 0.0 0.0 0.2 1.7 1.1 0.0 2.5 0.2 333.8 8.2 7.6 0.0 0.0 0.0 0.0 47.4 244.0 4.2 0.6 145.5 23.2 0.0 9.5 0.0 5.2 0.0 0.1 0.0 0.0 0.0 45.4 0.0 0.0 0.3 0.0 0.0 0.0 1.7 2.5 0.3 0.2 0.7 3.1 0.4 5.8 0.1 0.1 0.0 FCRL4 "CD307d, FCRH4, IGFP2, IRTA1" ENSG00000163518 "Fc receptor like 4" Q96PJ5 1 157573747-157598085 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.5" "Cell type enhanced" "Detected in single" "B-cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 47 "U-266/70: 4.6" "Not detected" "Not detected" HPA054030 Approved NA NA "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA054030: " "unprognostic (6.06e-2)" "unprognostic (3.41e-3)" "unprognostic (2.57e-1)" "unprognostic (5.08e-2)" "unprognostic (4.69e-4)" "unprognostic (2.06e-2)" "unprognostic (6.38e-2)" "unprognostic (1.99e-1)" "unprognostic (2.14e-1)" "unprognostic (3.37e-1)" "unprognostic (6.77e-2)" 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.3 0.0 0.0 0.2 0.0 0.0 10.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 FEN1 "FEN-1, MF1, RAD2" ENSG00000168496 "Flap structure-specific endonuclease 1" P39748 11 61792911-61797238 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 46.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 87.5;Extravillous trophoblasts: 70.9;Spermatocytes: 61.0;Spermatogonia: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002262, HPA006748" Enhanced Enhanced Nucleoplasm,Nucleoli NA Yes 160000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002262: AB_563729, HPA006748: AB_1848494" "unprognostic (1.82e-1)" "unprognostic (2.71e-2)" "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (1.26e-1)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.50e-2)" "unprognostic (9.82e-2)" "prognostic favorable (7.85e-4)" "unprognostic (2.82e-3)" "unprognostic (5.86e-2)" "prognostic unfavorable (5.73e-6)" "prognostic favorable (9.46e-4)" "unprognostic (1.10e-1)" "unprognostic (4.49e-3)" "unprognostic (4.04e-2)" 5.9 10.4 7.8 21.3 7.8 39.5 10.2 10.9 9.9 6.2 9.6 15.5 11.2 6.3 7.1 14.2 5.7 4.3 6.6 8.0 7.7 5.8 9.9 5.6 34.0 10.0 8.3 3.9 6.8 5.6 8.3 12.9 10.7 6.2 16.1 17.4 6.1 5.9 13.1 9.6 11.4 8.9 6.8 12.8 8.4 19.1 9.1 46.0 4.8 9.6 37.4 8.1 4.9 8.1 154.6 139.7 149.3 81.3 14.9 18.0 94.9 133.3 76.1 160.9 181.4 123.4 112.8 222.6 100.3 57.3 150.5 158.3 214.3 117.7 163.3 117.8 117.6 117.6 187.7 127.3 11.0 184.7 115.4 12.7 15.8 148.1 39.0 23.3 63.1 122.1 181.3 155.1 136.0 195.4 259.7 165.4 165.3 120.3 134.7 173.8 173.7 228.9 64.4 144.7 170.0 140.7 89.6 115.0 79.1 70.1 167.4 127.1 43.2 141.5 178.1 182.3 134.6 120.4 204.3 228.9 98.4 121.9 124.6 24.7 6.7 14.2 16.2 12.9 16.8 14.4 12.3 15.1 8.0 14.8 14.0 13.8 2.7 20.0 12.9 24.5 25.2 10.3 7.8 7.8 10.9 9.9 8.0 7.7 10.0 8.3 10.7 6.8 9.1 8.1 2.7 0.0 2.2 0.3 14.0 10.3 5.2 18.2 7.4 23.8 7.4 7.4 5.8 5.7 7.7 0.0 12.5 53.0 15.9 6.7 7.9 17.3 21.7 4.2 5.5 5.5 4.8 87.5 2.0 12.2 70.9 8.6 7.1 6.3 0.0 18.6 1.1 7.2 25.7 15.2 2.4 8.0 18.3 5.4 6.8 14.4 5.6 6.2 5.4 0.0 12.4 31.3 13.4 1.5 3.1 12.2 9.4 7.2 45.3 6.5 3.7 5.7 6.4 23.3 0.0 6.8 12.2 61.0 62.1 11.3 6.1 30.9 11.0 9.0 22.0 5.2 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 83.4;lymphoid tissue: 110.9" "Cell type enhanced" "Detected in many" "Adipocytes: 46.8;Hofbauer cells: 48.7;Kupffer cells: 92.3;Macrophages: 51.9;monocytes: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 315.8" "Group enriched" "Detected in many" 4 "dendritic cells: 162.6;granulocytes: 315.8;monocytes: 151.7" "Cell line enhanced" "Detected in many" "HEL: 63.5;HL-60: 56.9;HMC-1: 116.6;NB-4: 76.1;THP-1: 110.8;U-937: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 30.8 8.0 9.4 20.2 8.8 83.4 21.3 9.6 10.8 18.1 9.6 12.5 5.8 15.7 2.4 5.9 19.0 14.0 19.6 8.3 8.7 18.9 25.2 30.9 13.8 11.1 9.2 13.5 7.8 2.3 5.6 16.3 10.1 17.9 4.6 1.5 58.3 8.0 6.1 8.0 12.5 10.7 10.4 110.9 9.6 4.5 10.9 4.2 16.0 7.0 5.7 15.1 13.5 9.8 0.4 0.8 0.8 10.3 3.1 8.8 17.9 2.9 0.1 5.1 2.9 2.6 0.1 6.8 0.5 6.0 0.2 1.5 1.7 0.3 1.6 3.3 1.1 63.5 0.0 11.9 6.8 56.9 116.6 8.8 0.1 7.6 0.0 0.0 31.2 9.4 1.8 0.2 0.0 21.3 1.8 76.1 3.2 2.5 0.0 8.6 0.1 0.1 0.0 0.2 0.4 0.1 0.0 2.8 2.3 2.9 0.1 110.8 24.9 0.2 10.4 0.2 0.2 0.1 8.0 2.5 0.3 48.0 2.4 64.4 151.7 315.8 0.5 88.6 0.4 5.2 0.3 0.4 162.6 4.1 0.2 0.3 100.5 51.4 39.8 65.0 0.2 81.5 9.4 8.8 9.6 10.8 8.3 8.7 11.1 9.2 10.1 10.4 10.9 9.8 46.8 3.2 5.8 3.6 5.0 3.8 5.4 0.5 0.6 0.2 4.1 3.8 3.4 8.6 0.5 1.8 0.0 5.3 25.6 0.6 3.9 7.3 1.7 2.0 4.2 29.1 3.0 8.0 2.8 4.3 4.2 9.0 2.0 4.2 29.2 10.7 20.0 15.0 48.7 0.0 0.2 2.0 2.0 92.3 27.9 8.4 9.0 51.9 7.2 5.6 57.8 2.5 26.8 2.0 0.3 2.1 2.0 10.1 4.0 3.1 0.7 1.5 0.2 1.9 13.1 4.6 12.9 4.4 15.9 1.0 2.8 4.5 6.7 3.3 3.7 5.2 FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 70.8" "Cell type enriched" "Detected in some" 32 "Enteroendocrine cells: 744.9" "Group enriched" "Detected in some" 10 "pancreatic cancer: 3.0;prostate cancer: 9.9;stomach cancer: 2.4" "Group enriched" "Detected in many" 7 "midbrain: 70.8;pons: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HMC-1: 35.5;SH-SY5Y: 43.8" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 4.8;pons: 2.7" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles" "HPA067679: AB_2685884" "unprognostic (4.58e-1)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "prognostic favorable (4.85e-4)" "unprognostic (2.87e-1)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" 0.1 2.3 0.0 0.0 1.7 0.0 0.0 0.0 0.6 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 6.2 70.8 0.0 1.3 0.0 2.6 0.0 20.1 2.2 1.8 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.1 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.6 0.1 6.2 70.8 20.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 744.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 6.0 0.0 0.0 3.4 1.2 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.1 FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583128-154590745 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 388 "liver: 18396.9" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 17365.8" "Cancer enriched" "Detected in many" 43 "liver cancer: 2431.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 429.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 407000000 140000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB016776: , HPA051370: AB_2681458, HPA064755: AB_2685345" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.29e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.23e-6)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" 2.1 1.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.5 0.0 0.6 0.6 0.7 0.9 13.2 1.2 0.0 0.0 18.8 18396.9 5.3 0.1 0.0 0.0 0.7 18.8 0.0 0.5 0.9 0.0 0.4 0.0 0.0 0.5 0.0 0.5 0.6 0.9 0.0 0.0 9.9 47.4 3.7 0.0 0.1 0.4 0.0 0.1 0.6 0.7 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 0.0 2.7 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.4 0.1 429.3 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.5 6.1 0.0 0.0 0.5 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 0.0 0.0 1.0 0.0 1.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 414.6 3.2 0.0 0.0 0.0 0.0 0.0 1.9 38.6 28.3 0.1 0.2 8.1 0.0 205.9 0.0 1.8 0.1 0.1 1.1 1.3 0.0 0.0 238.8 17365.8 0.1 0.0 0.0 0.0 0.0 328.3 0.0 46.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 1.2 0.0 0.0 0.0 2.3 9.5 0.0 0.0 0.0 0.1 17.4 0.7 0.0 0.0 0.1 17.6 0.0 0.0 0.0 FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 373 "liver: 17944.9" "Cell type enriched" "Detected in some" 40 "Hepatocytes: 17273.6" "Cancer enriched" "Detected in many" 42 "liver cancer: 2262.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "Hep G2: 249.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" NA NA 110000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB008624: AB_1615610, HPA001900: AB_1078865, HPA001901: AB_1078864" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (4.65e-2)" "unprognostic (3.44e-1)" "unprognostic (2.20e-3)" "unprognostic (1.42e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.48e-2)" "unprognostic (7.91e-2)" 2.0 0.8 0.0 0.0 0.0 0.1 2.8 0.0 0.0 1.3 0.0 0.5 0.0 0.6 0.3 0.6 0.8 0.4 1.4 0.0 0.0 48.0 17944.9 0.5 0.1 0.0 0.0 0.6 3.3 0.0 0.5 1.0 0.0 0.4 0.0 0.0 0.4 0.0 0.5 0.5 1.2 0.0 0.0 12.1 6.8 0.5 0.0 0.3 0.4 0.0 0.1 0.5 0.7 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.2 0.1 249.9 0.0 5.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.8 0.0 0.9 0.0 2.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 39.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 251.6 0.0 3.7 0.0 0.0 0.0 0.0 1.9 10.6 0.5 0.6 0.8 13.1 1.8 302.1 0.0 3.8 0.2 0.0 0.0 5.9 0.0 0.0 318.1 17273.6 0.3 0.0 0.0 0.0 0.0 421.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.7 0.0 0.0 0.0 FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 295.2;choroid plexus: 125.8" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Cardiomyocytes: 62.4;Muller glia cells: 69.4;Oligodendrocytes: 119.8" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.6;BJ hTERT+: 33.0;BJ hTERT+ SV40 Large T+: 35.9;BJ hTERT+ SV40 Large T+ RasG12V: 45.0;HBF TERT88: 64.3;hTEC/SVTERT24-B: 45.4;LHCN-M2: 30.6;U-2 OS: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" 17.9 3.3 206.3 1.6 259.3 1.1 12.5 213.9 295.2 1.3 125.8 2.4 1.0 3.1 7.9 2.0 1.7 2.5 50.2 183.5 245.5 66.5 1.7 2.8 1.2 236.2 237.7 0.9 0.8 4.3 6.5 2.1 259.9 1.8 1.3 18.8 7.3 2.3 2.2 1.7 1.2 2.5 225.4 6.9 0.8 2.0 244.3 1.5 5.6 7.8 2.0 1.2 1.0 272.8 5.6 0.3 0.3 1.5 1.1 3.3 1.8 44.6 33.0 35.9 45.0 0.2 0.2 1.3 3.1 15.4 2.1 0.7 0.0 3.5 64.3 0.2 0.0 0.0 0.8 0.4 0.6 0.0 0.4 1.6 1.1 45.4 2.7 9.7 0.0 0.2 0.0 1.6 30.6 0.7 0.1 0.9 1.4 0.1 1.4 0.2 1.5 0.6 1.5 0.2 1.1 2.3 0.1 0.9 0.6 8.0 0.0 0.2 1.1 5.8 33.0 0.8 21.3 0.8 0.4 0.3 8.2 0.3 1.6 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.2 0.1 0.0 206.3 259.3 213.9 295.2 183.5 245.5 236.2 237.7 259.9 225.4 244.3 272.8 1.4 0.0 0.0 75.1 0.1 0.4 5.0 5.7 7.4 3.5 1.2 25.4 62.4 0.0 2.1 20.2 16.7 1.1 0.1 0.0 0.0 1.1 0.4 0.0 0.7 4.8 0.0 0.0 13.0 0.0 0.5 4.7 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 14.6 0.0 12.2 0.0 0.0 1.4 0.0 0.2 3.6 29.0 0.0 69.4 0.0 15.1 119.8 0.6 0.0 0.4 0.0 5.3 0.0 0.3 0.1 11.6 6.6 0.5 23.4 0.1 0.1 0.6 0.0 0.8 0.4 0.0 0.0 0.7 FGF17 FGF-13 ENSG00000158815 "Fibroblast growth factor 17" O60258 8 22042398-22048809 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7;choroid plexus: 10.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 9.3;Cone photoreceptor cells: 14.6;Excitatory neurons: 10.6;Inhibitory neurons: 13.1" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6;testis cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.1;RPMI-8226: 1.8" "Region enriched" "Detected in single" 4 "basal ganglia: 2.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" HPA052600 Uncertain "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA052600: AB_2681881" "unprognostic (3.45e-2)" "unprognostic (1.64e-2)" "unprognostic (3.03e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (3.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (7.92e-5)" "unprognostic (6.85e-2)" "unprognostic (2.58e-4)" "unprognostic (6.55e-3)" "unprognostic (7.18e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-3)" 0.5 3.9 15.1 0.0 14.9 0.1 0.4 22.0 25.7 3.0 10.6 0.4 0.0 1.1 0.1 0.2 1.5 0.2 0.5 14.3 14.2 1.4 0.4 0.7 0.0 11.9 12.2 1.5 1.2 0.8 5.1 0.1 12.2 2.7 0.0 1.1 0.7 0.1 0.0 0.5 0.4 0.3 10.9 3.6 0.5 0.7 14.2 0.4 4.8 0.0 0.0 0.6 1.3 14.4 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 14.9 22.0 25.7 14.3 14.2 11.9 12.2 12.2 10.9 14.2 14.4 0.2 0.0 0.0 2.3 0.0 0.0 0.3 0.1 0.0 9.3 0.2 0.4 1.1 0.0 0.2 0.0 14.6 0.1 0.0 0.1 0.0 0.1 1.8 0.0 0.1 0.1 0.0 0.0 10.6 0.2 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 1.7 13.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.8 1.0 0.0 0.6 0.0 2.0 2.4 0.1 0.0 1.2 0.1 0.2 0.0 0.0 0.2 1.3 0.0 0.3 0.2 0.2 0.5 0.0 0.0 0.3 0.1 0.4 0.0 0.1 FGF18 "FGF-18, ZFGF5" ENSG00000156427 "Fibroblast growth factor 18" O76093 5 171419647-171457626 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 16.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 19.8;Cardiomyocytes: 24.4;Endometrial ciliated cells: 13.0;Glandular and luminal cells: 24.9" "Group enriched" "Detected in many" 6 "endometrial cancer: 19.0;ovarian cancer: 21.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "EFO-21: 188.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 2.3" HPA018795 Uncertain "Secreted in other tissues" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA018795: AB_1848523" "unprognostic (3.01e-1)" "unprognostic (2.38e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-3)" "unprognostic (6.62e-3)" "unprognostic (1.50e-1)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-3)" "unprognostic (3.65e-2)" "unprognostic (3.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.37e-8)" "unprognostic (7.33e-2)" "unprognostic (2.58e-1)" "unprognostic (3.19e-1)" "unprognostic (2.76e-2)" 4.2 0.3 1.1 0.3 1.2 0.0 2.1 1.1 2.1 1.0 1.1 0.9 0.6 0.9 0.1 0.3 1.5 0.7 16.1 1.1 1.2 0.7 0.1 2.6 0.3 1.4 1.3 0.4 0.5 0.1 1.6 0.5 1.6 1.2 0.1 0.1 1.1 0.3 3.8 1.6 0.7 0.4 1.1 0.5 0.6 0.8 1.5 0.3 1.9 0.4 0.2 0.8 0.5 1.2 0.0 0.3 0.3 0.9 0.0 0.0 0.3 0.1 0.0 0.0 0.1 3.4 0.4 0.2 188.2 0.0 0.2 0.2 0.0 0.1 0.0 3.1 0.3 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.0 0.9 0.1 3.4 0.0 0.1 0.0 0.3 2.1 0.1 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 1.5 0.1 0.5 0.0 0.2 0.6 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 1.1 2.1 1.1 1.2 1.4 1.3 1.6 1.1 1.5 1.2 6.9 6.4 0.0 0.0 2.0 2.4 2.6 0.5 6.2 0.1 6.6 19.8 24.4 1.5 1.3 1.8 0.0 0.1 3.4 0.5 0.0 0.0 6.2 13.0 3.1 4.2 1.8 0.0 0.8 0.0 0.3 9.4 0.5 24.9 0.0 0.0 2.9 0.0 0.1 0.0 2.1 1.0 0.0 0.0 2.1 0.7 0.3 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.4 0.4 3.2 1.1 0.0 0.0 0.0 0.0 5.4 4.6 0.7 1.6 5.6 3.1 0.0 2.4 0.5 1.8 0.9 FGF19 ENSG00000162344 "Fibroblast growth factor 19" O95750 11 69698238-69704022 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "gallbladder: 237.1" "Group enriched" "Detected in some" 4 "Cholangiocytes: 24.3;Ductal cells: 15.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "CAPAN-2: 138.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA036082 Approved "Secreted to blood" NA NA 133000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "HPA036082: AB_10669665" "unprognostic (7.46e-3)" "unprognostic (2.43e-3)" "unprognostic (5.52e-3)" "unprognostic (1.22e-1)" "unprognostic (4.68e-3)" "unprognostic (6.45e-2)" "unprognostic (5.72e-3)" "unprognostic (2.26e-1)" "unprognostic (6.39e-3)" "unprognostic (1.66e-2)" "unprognostic (8.82e-3)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.4 0.1 0.0 237.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 138.2 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.2 0.0 0.0 0.7 1.4 0.6 24.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.1 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.0 1.3 0.0 0.0 0.0 0.3 1.8 FGF2 FGFB ENSG00000138685 "Fibroblast growth factor 2" P09038 4 122826708-122898236 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 33.7;Astrocytes: 111.0;Endometrial stromal cells: 40.6;Fibroblasts: 77.1;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 243.8;BJ hTERT+: 148.4;fHDF/TERT166: 278.2;hTERT-HME1: 147.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000125, HPA065502" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Secreted in other tissues" NA NA 92500 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear bodies" "CAB000125: , HPA065502: " "unprognostic (1.53e-2)" "unprognostic (3.12e-1)" "unprognostic (1.08e-1)" "unprognostic (7.42e-2)" "unprognostic (2.10e-1)" "unprognostic (3.33e-1)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (2.82e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (9.85e-4)" "unprognostic (3.37e-1)" "unprognostic (4.61e-3)" "unprognostic (2.36e-1)" "unprognostic (1.81e-1)" "unprognostic (4.45e-2)" "unprognostic (3.45e-3)" 24.3 2.6 14.8 5.3 16.1 0.1 9.5 12.2 14.7 8.7 14.2 14.1 1.7 14.2 4.5 4.7 8.0 7.1 5.0 12.2 18.8 4.0 2.0 8.3 1.8 18.6 20.5 12.6 1.5 4.7 3.2 6.4 15.6 7.6 4.0 3.4 3.5 8.7 1.4 1.9 3.7 12.6 16.8 1.1 6.2 1.9 18.3 1.6 2.4 4.8 1.8 14.8 6.1 13.3 4.7 14.1 7.8 30.5 18.8 31.1 0.0 243.8 148.4 104.3 60.2 0.2 0.4 0.0 20.5 278.2 81.8 0.7 8.1 0.5 104.3 12.3 3.3 0.0 28.7 0.2 55.3 1.4 0.1 16.8 1.7 103.6 147.6 52.0 11.8 0.0 6.9 8.4 27.4 0.1 0.1 0.2 21.6 0.1 5.4 0.0 3.9 0.1 33.0 0.0 4.4 4.0 48.4 0.1 2.0 44.7 0.1 0.5 10.6 85.7 12.2 32.0 20.0 8.6 10.3 0.0 24.7 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 16.1 12.2 14.7 12.2 18.8 18.6 20.5 15.6 16.8 18.3 13.3 33.7 6.4 0.0 111.0 0.3 1.7 1.6 0.8 2.8 4.6 4.5 8.9 4.7 0.0 1.3 7.3 0.0 2.7 0.4 0.0 3.9 8.2 10.9 1.5 40.6 11.5 1.8 0.4 1.8 1.0 0.1 77.1 0.0 1.6 0.0 5.7 17.2 1.3 0.5 0.0 6.6 0.0 0.0 0.0 2.4 3.8 9.9 1.7 5.4 15.9 0.6 9.3 0.0 42.3 5.8 11.0 0.0 8.2 1.6 16.0 0.0 0.6 0.0 2.0 0.0 15.2 14.2 4.7 1.1 0.3 1.3 4.8 0.5 0.1 0.0 2.0 FGF23 ENSG00000118972 "Fibroblast growth factor 23" Q9GZV9 12 4368227-4379712 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" Differentiation "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 126.3;choroid plexus: 104.9" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 10.4;Early spermatids: 6.6;Hepatic stellate cells: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 10.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 10.8" "Cell line enhanced" "Detected in some" "AF22: 1.9;HBEC3-KT: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to blood" NA NA 56800 "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (1.31e-1)" "unprognostic (2.18e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" 0.2 0.1 74.8 0.1 73.5 0.5 0.2 73.8 126.3 0.0 104.9 0.2 0.3 0.3 1.2 0.2 0.3 0.1 5.0 74.1 74.1 0.2 4.1 0.2 0.2 73.8 86.6 0.2 0.1 0.1 0.0 0.2 77.8 0.1 0.6 2.3 0.5 0.0 1.2 0.3 0.1 0.3 72.9 0.5 0.2 0.5 73.3 0.1 0.1 0.3 0.6 0.1 0.0 78.6 0.0 0.0 1.9 0.6 0.9 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.7 0.1 0.0 0.3 0.1 0.4 0.2 1.4 0.0 0.0 0.2 0.0 0.3 0.2 0.5 0.4 0.1 0.5 0.0 0.9 1.1 0.1 0.1 0.0 0.1 0.8 0.0 0.0 0.2 0.5 0.5 0.1 0.0 0.3 0.0 0.3 0.2 0.4 0.4 0.3 0.0 0.6 0.1 0.3 0.4 0.3 0.0 0.7 0.1 0.5 0.1 0.0 0.0 0.1 0.4 0.1 0.4 10.8 1.4 2.0 1.6 1.5 1.9 1.8 1.5 1.2 1.2 1.9 1.7 1.7 4.8 2.2 2.5 1.9 1.6 1.1 74.8 73.5 73.8 126.3 74.1 74.1 73.8 86.6 77.8 72.9 73.3 78.6 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.9 1.5 0.0 0.0 10.4 0.1 0.3 0.0 0.0 0.0 6.6 0.0 0.2 0.5 0.0 0.0 0.8 0.0 0.1 0.4 0.0 0.1 0.0 0.0 13.6 0.0 0.2 1.7 0.3 0.0 0.0 0.6 0.3 1.8 0.3 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.2 FGF3 "HBGF-3, INT2" ENSG00000186895 "Fibroblast growth factor 3" P11487 11 69809968-69819416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 36 "brain: 3.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.4" "Region enriched" "Detected in single" 5 "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 3.1" "Not detected" "Not detected" HPA012692 Enhanced "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA012692: AB_1848526" "unprognostic (6.42e-3)" "unprognostic (7.82e-2)" "unprognostic (1.89e-1)" "unprognostic (3.61e-1)" "unprognostic (7.75e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.1 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF4 "HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF" ENSG00000075388 "Fibroblast growth factor 4" P08620 11 69771022-69775341 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 1.1;Early spermatids: 3.1;Late spermatids: 1.4;Spermatocytes: 1.5" "Cancer enriched" "Detected in some" 5 "testis cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "NTERA-2: 16.1;SuSa: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA011209 Uncertain "Secreted in other tissues" NA NA 326000 "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA011209: AB_1848527" "unprognostic (1.47e-2)" "unprognostic (6.22e-2)" "unprognostic (7.77e-2)" "unprognostic (8.56e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF6 ENSG00000111241 "Fibroblast growth factor 6" P10767 12 4428155-4445614 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "skeletal muscle: 16.0;tongue: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 2.4;REH: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "unprognostic (4.29e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 2.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FGF8 AIGF ENSG00000107831 "Fibroblast growth factor 8" P55075 10 101770130-101780369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "skeletal muscle: 48.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.1;testis cancer: 3.3" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 17 "RH-30: 37.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.56e-1)" "unprognostic (3.90e-3)" "unprognostic (1.12e-2)" "unprognostic (4.88e-1)" "unprognostic (2.47e-2)" "unprognostic (9.09e-2)" "unprognostic (8.75e-3)" "unprognostic (8.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.95e-2)" "unprognostic (1.17e-2)" "unprognostic (2.35e-9)" "unprognostic (6.17e-3)" "unprognostic (9.01e-2)" "unprognostic (1.97e-1)" 0.5 0.0 0.7 0.0 0.7 0.2 0.2 0.6 1.2 0.1 0.8 0.2 0.3 0.2 0.2 0.9 0.1 0.3 0.3 0.9 1.1 0.1 0.1 0.3 0.3 0.5 0.7 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.1 0.5 0.0 0.1 48.7 0.2 0.0 0.0 0.4 0.6 0.1 1.1 0.7 0.0 0.2 0.0 0.0 0.2 0.0 1.0 0.6 0.1 0.3 1.4 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.6 0.7 0.4 0.6 0.0 0.0 0.5 0.3 0.0 0.0 1.1 1.0 0.4 0.3 0.5 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.1 0.0 1.0 0.3 0.9 0.0 0.4 0.6 2.2 0.2 0.0 0.1 0.6 37.8 0.8 0.0 0.2 0.9 0.9 0.0 0.6 0.5 0.0 0.6 0.1 0.6 0.6 1.1 0.8 0.2 0.2 0.8 1.3 0.8 0.7 0.8 1.9 0.4 0.5 0.3 0.5 0.6 0.4 0.4 0.4 0.4 0.5 0.6 0.5 1.1 0.7 0.9 0.4 0.5 0.3 0.7 0.7 0.6 1.2 0.9 1.1 0.5 0.7 0.6 0.4 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 FGF9 ENSG00000102678 "Fibroblast growth factor 9" P31371 13 21671073-21704498 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 10.7;retina: 8.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 39.2;Excitatory neurons: 36.7;Horizontal cells: 40.4;Inhibitory neurons: 54.7;Muller glia cells: 138.8" "Group enriched" "Detected in some" 5 "endometrial cancer: 3.7;ovarian cancer: 1.2;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.4;HEK 293: 1.4;JURKAT: 2.1;RPMI-8226: 2.1;RPTEC TERT1: 3.0;SCLC-21H: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067007 Enhanced Approved "Secreted in other tissues" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" "HPA067007: AB_2732755" "unprognostic (6.59e-3)" "unprognostic (9.09e-3)" "unprognostic (2.15e-2)" "unprognostic (9.24e-2)" "unprognostic (2.19e-1)" "unprognostic (2.37e-2)" "unprognostic (7.42e-4)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (3.86e-1)" "unprognostic (2.38e-3)" "unprognostic (7.93e-2)" "prognostic favorable (1.70e-6)" "unprognostic (5.38e-2)" "unprognostic (1.27e-1)" "unprognostic (3.49e-1)" "unprognostic (6.92e-2)" 2.4 4.0 1.1 0.1 1.4 0.2 0.2 5.8 4.7 1.5 0.2 0.8 0.7 1.6 0.2 0.2 0.4 0.4 2.7 1.3 1.9 10.7 0.0 0.9 0.1 3.7 1.6 1.0 0.5 0.1 2.2 0.1 4.3 0.3 1.2 8.2 0.3 0.5 0.5 0.1 1.8 0.3 1.2 0.1 0.8 0.5 3.0 0.1 0.1 0.5 0.0 1.2 0.8 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.9 0.5 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.6 2.1 3.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.4 5.8 4.7 1.3 1.9 3.7 1.6 4.3 1.2 3.0 2.1 0.9 9.6 5.6 12.1 1.8 1.7 0.2 0.6 0.0 14.4 0.7 2.7 25.7 0.0 1.3 3.7 0.0 0.1 3.2 1.7 39.2 0.4 9.4 13.1 2.6 1.6 18.6 0.0 36.7 0.0 0.0 3.9 0.0 26.6 0.0 1.2 0.0 0.0 0.1 40.4 54.7 2.7 0.0 0.0 1.6 2.9 0.6 0.5 1.8 1.9 1.6 138.8 3.1 9.5 1.7 0.2 0.5 0.0 1.9 0.1 10.9 1.1 0.0 5.9 0.0 1.0 0.7 6.3 6.2 0.1 1.4 0.3 3.2 0.1 7.5 0.1 FGFBP1 "FGFBP, HBP17" ENSG00000137440 "Fibroblast growth factor binding protein 1" Q14512 4 15935577-15938740 "Cancer-related genes, Predicted secreted proteins" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 117.1;esophagus: 421.8;vagina: 172.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1044.3;Basal respiratory cells: 596.2;Squamous epithelial cells: 528.5;Suprabasal keratinocytes: 786.2;Urothelial cells: 303.6" "Group enriched" "Detected in many" 5 "cervical cancer: 117.5;head and neck cancer: 246.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 556.3;HBEC3-KT: 968.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004332 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA004332: AB_1078856" "unprognostic (2.87e-3)" "unprognostic (3.55e-1)" "unprognostic (5.03e-2)" "unprognostic (6.99e-2)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (5.03e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-2)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (3.31e-3)" 0.6 0.1 0.0 1.7 0.0 0.1 13.5 0.0 0.0 117.1 0.0 22.1 1.8 0.5 0.1 421.8 1.2 0.3 0.2 0.0 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.1 0.4 0.0 0.2 1.1 0.0 1.7 15.6 0.0 59.7 0.1 0.1 91.2 7.0 1.1 0.0 0.1 2.0 0.0 0.0 0.3 0.7 0.0 38.4 14.9 172.3 0.0 150.7 10.5 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 189.0 0.0 10.9 0.0 0.2 556.3 0.0 968.2 0.0 0.0 1.2 0.0 2.0 0.0 0.2 0.0 0.4 0.1 141.0 0.0 17.7 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 7.9 75.2 0.0 0.0 0.0 93.4 6.7 0.0 0.0 0.2 0.0 0.2 0.0 0.9 0.5 0.1 0.2 0.3 0.0 0.3 0.0 0.1 0.2 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 8.4 0.0 0.3 1044.3 182.5 596.2 217.4 0.0 11.8 3.2 0.1 0.0 223.2 0.0 0.0 0.2 0.2 49.6 0.0 49.7 0.0 52.8 3.3 6.3 0.0 0.0 0.0 7.5 2.4 6.2 0.0 65.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.1 42.7 0.0 60.6 0.0 0.0 0.9 74.7 0.0 0.6 0.0 1.0 0.0 0.0 139.1 50.8 0.0 0.0 90.8 0.7 0.0 56.8 0.0 0.0 0.0 10.4 0.0 0.0 528.5 786.2 2.3 2.1 0.0 26.1 303.6 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 148.3;esophagus: 139.7;skin 1: 271.5" "Cell type enhanced" "Detected in many" "Astrocytes: 410.4;Basal keratinocytes: 103.8;Cholangiocytes: 91.5;Suprabasal keratinocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 48.2;HaCaT: 34.9;Hep G2: 80.6;NTERA-2: 36.1;RT4: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" NA NA 2500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" 1.6 1.6 118.0 1.5 140.6 1.4 5.5 115.6 104.0 23.7 37.4 12.2 19.5 1.5 2.8 139.7 2.2 7.9 4.8 100.8 107.6 39.3 40.7 7.4 0.4 144.7 129.2 0.5 76.4 0.2 16.1 9.3 109.8 13.8 5.2 0.2 20.2 15.0 1.3 271.5 14.7 0.4 108.9 4.0 7.8 17.6 148.3 1.7 1.5 0.9 11.1 23.1 60.9 81.2 0.0 3.8 19.5 5.6 0.0 0.3 22.1 2.4 0.3 0.8 0.4 48.2 1.0 0.0 17.8 0.7 0.7 34.9 5.5 0.3 0.3 0.2 19.3 14.2 3.9 80.6 0.1 0.0 0.6 0.0 10.9 0.2 0.1 0.1 0.1 2.3 16.7 0.1 0.0 23.9 0.8 0.5 36.1 19.5 0.1 1.2 1.0 0.3 2.8 64.1 5.7 1.6 1.9 4.0 0.0 22.2 20.4 2.5 1.0 0.0 2.1 0.5 1.6 0.1 0.0 0.0 0.2 1.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.0 140.6 115.6 104.0 100.8 107.6 144.7 129.2 109.8 108.9 148.3 81.2 2.2 0.0 32.5 410.4 1.1 103.8 4.1 29.8 23.9 0.0 4.8 1.5 3.1 91.5 37.6 14.7 0.0 0.5 1.6 36.1 0.0 5.0 7.9 3.0 1.7 3.4 4.2 0.0 0.5 0.7 12.0 3.2 3.6 4.0 0.0 0.1 16.1 30.4 0.6 0.0 1.3 20.7 4.1 1.2 6.5 1.3 0.6 0.6 12.4 14.0 0.6 0.1 0.0 34.2 2.2 0.4 18.0 0.4 0.0 4.2 21.2 9.9 9.8 0.6 0.0 0.7 2.9 0.4 25.9 55.0 88.7 0.8 0.7 0.1 17.0 12.8 FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086905-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 82.5;lung: 65.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 78.6;Hepatocytes: 31.2;Skeletal myocytes: 141.2;Theca cells: 36.7;Undifferentiated cells: 38.6" "Cancer enhanced" "Detected in many" "liver cancer: 42.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CACO-2: 173.9;Hep G2: 176.4;RH-30: 274.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" NA NA 7400000 "Cluster 18: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" 1.2 14.0 1.1 4.1 1.1 0.5 4.5 2.7 2.1 3.0 1.2 18.0 21.3 2.4 0.2 3.2 4.2 10.2 2.2 1.4 1.0 40.2 82.5 65.4 0.8 0.7 0.8 27.5 29.5 0.2 2.0 2.1 0.9 5.2 6.0 1.5 1.1 0.7 6.6 1.7 20.0 1.1 0.7 22.7 8.8 5.9 1.1 0.2 0.9 1.9 0.2 6.4 3.2 1.3 3.2 48.8 1.0 11.7 0.1 0.1 24.5 0.2 0.1 0.2 0.3 173.9 6.5 5.3 23.0 0.1 2.4 2.8 9.5 1.8 0.1 3.2 13.8 0.5 2.8 176.4 5.2 0.6 4.7 1.1 0.2 8.4 0.2 0.3 0.2 3.5 18.1 0.7 3.9 40.3 0.1 3.6 29.2 30.9 4.5 8.2 274.3 30.9 22.9 0.4 1.8 2.9 1.8 12.4 5.9 5.9 11.7 2.5 1.1 0.0 23.4 0.3 0.7 1.6 1.9 3.7 0.1 1.1 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.1 1.1 2.7 2.1 1.4 1.0 0.7 0.8 0.9 0.7 1.1 1.3 0.3 0.0 0.0 0.3 0.3 0.6 0.7 0.4 0.0 0.9 2.9 2.0 0.9 78.6 0.1 3.7 0.0 1.3 0.1 12.9 3.9 10.9 0.1 1.6 0.3 0.7 4.2 0.0 0.5 4.9 3.8 9.6 9.7 2.9 0.0 0.7 3.9 31.2 0.3 0.0 0.5 10.1 0.0 0.9 0.5 0.0 0.6 0.7 0.0 1.9 0.6 0.6 0.0 0.5 0.1 3.0 4.4 1.5 0.1 1.7 15.9 21.6 0.1 0.4 19.7 141.2 0.7 3.0 9.9 0.8 0.4 8.8 0.4 36.7 38.6 0.5 FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 330 "liver: 16556.3" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 10221.7" "Cancer enriched" "Detected in many" 19 "liver cancer: 1503.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "Hep G2: 735.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 267000000000 73000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "CAB033120: AB_2103818, HPA027529: AB_10601322, HPA074638: " "unprognostic (1.26e-2)" "unprognostic (4.77e-3)" "unprognostic (6.33e-3)" "unprognostic (3.69e-3)" "unprognostic (2.18e-3)" "unprognostic (9.63e-2)" "unprognostic (7.57e-3)" "prognostic unfavorable (1.00e-6)" "unprognostic (1.75e-3)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" 1.7 34.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.3 0.0 0.4 0.0 0.4 0.2 0.6 0.7 25.0 1.2 0.0 0.0 8.8 16556.3 50.2 0.1 0.0 0.0 1.4 15.8 0.0 0.4 6.3 0.0 0.4 0.0 0.0 0.4 0.3 0.4 0.5 0.6 0.0 0.0 9.1 8.7 3.0 0.1 0.3 0.4 0.0 0.0 0.5 0.6 0.1 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.2 0.0 1.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.5 0.4 735.3 0.2 8.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.3 0.0 0.6 0.0 0.0 0.3 6.4 0.0 0.0 0.6 0.0 0.0 5.3 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.1 0.1 1.7 0.0 3.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 19.2 214.4 0.0 31.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 633.4 2.5 0.0 0.0 0.0 0.0 0.1 0.0 21.9 4.3 0.0 0.1 9.2 0.0 157.7 0.0 48.5 0.2 0.5 0.0 0.1 11.4 1.1 202.4 10221.7 0.2 0.0 0.0 0.0 0.0 289.5 0.0 0.5 0.0 0.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 161.8 0.0 0.0 0.0 0.0 0.0 1.6 1.5 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.0 0.4 17.3 0.2 0.0 0.0 FH ENSG00000091483 "Fumarate hydratase" P07954 1 241497603-241519755 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Tricarboxylic acid cycle" Lyase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017785, HPA025770, HPA025948, HPA027341" Enhanced Supported Enhanced Mitochondria NA NA 1800000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222" "unprognostic (1.03e-2)" "unprognostic (3.82e-2)" "unprognostic (9.46e-3)" "unprognostic (2.18e-1)" "unprognostic (2.10e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (5.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.27e-2)" "unprognostic (1.09e-1)" "prognostic favorable (2.76e-7)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (4.41e-2)" "unprognostic (1.24e-2)" 43.4 75.2 30.4 31.0 33.3 31.4 37.3 33.5 42.0 28.9 43.9 66.8 68.2 36.9 26.1 51.1 27.9 23.7 179.0 33.9 33.1 101.8 276.4 26.4 30.0 31.8 31.0 24.9 38.1 95.0 31.1 32.1 32.1 33.5 69.0 58.8 42.0 38.4 213.4 40.3 59.1 42.0 32.4 30.1 53.6 44.4 32.7 31.3 34.6 229.3 40.4 37.5 33.7 33.0 129.2 105.6 97.9 89.0 93.9 110.0 154.9 155.7 121.1 171.6 107.1 152.2 78.0 81.1 100.3 119.9 75.0 178.4 151.7 115.8 148.4 93.5 48.9 76.3 102.2 131.4 84.1 180.2 66.7 80.2 70.7 96.6 108.0 60.2 107.2 175.8 236.3 101.7 126.9 64.3 156.6 120.1 104.5 186.2 223.6 127.4 107.2 365.7 167.4 107.6 125.4 108.4 131.1 153.3 104.0 67.2 117.1 120.9 106.5 76.6 98.9 137.0 264.0 90.3 103.7 97.3 85.7 203.5 112.6 11.9 22.8 4.9 16.1 33.3 21.0 27.2 18.8 15.1 46.7 25.1 22.3 21.1 1.3 18.3 29.1 23.1 23.8 16.7 30.4 33.3 33.5 42.0 33.9 33.1 31.8 31.0 32.1 32.4 32.7 33.0 17.1 38.5 30.2 9.4 25.0 20.0 24.6 69.5 17.1 24.7 19.9 17.5 173.5 35.8 40.0 23.9 14.6 101.6 13.7 44.0 78.2 60.4 226.0 25.4 23.5 18.6 18.0 37.7 12.7 45.0 58.7 25.5 26.5 25.4 19.0 24.9 13.6 80.4 50.7 35.3 14.9 40.6 48.8 18.5 14.4 37.4 23.9 23.9 24.9 8.4 27.9 35.0 10.3 8.0 14.4 29.4 35.7 26.7 41.3 19.0 66.1 86.0 29.2 39.1 39.5 27.7 67.9 84.7 47.1 32.1 18.6 166.1 14.9 48.4 74.2 22.8 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad diadenosine triphosphatase" P49789 3 59747277-61251459 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 94.0" "Cell type enhanced" "Detected in many" "Astrocytes: 609.8;Inhibitory neurons: 450.5;Microglial cells: 337.3;Oligodendrocyte precursor cells: 1086.7;Oligodendrocytes: 1111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "naive CD4 T-cell: 87.6" "Lineage enriched" "Detected in all" 12 "T-cells: 87.6" "Cell line enhanced" "Detected in many" "RPMI-8226: 17.5;U-266/70: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 12000 "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favorable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 5.6 24.4 13.7 6.2 18.3 8.0 9.0 13.0 17.3 5.4 94.0 6.9 6.4 3.5 6.9 5.0 6.6 9.8 15.8 19.7 16.4 24.9 9.6 4.7 7.6 18.9 17.0 6.8 13.0 18.1 7.9 3.0 18.9 5.3 5.8 7.6 8.5 4.7 10.6 8.1 5.3 4.7 15.0 5.0 8.6 5.5 15.9 12.1 11.7 7.2 5.3 6.7 4.2 19.8 0.1 0.0 1.4 0.0 0.6 0.1 2.5 0.1 0.2 0.1 0.0 2.7 4.2 4.0 0.7 0.1 3.0 0.0 12.7 3.2 0.0 2.2 5.0 3.3 2.0 6.4 3.3 8.7 0.1 9.1 5.2 0.2 6.9 0.3 0.0 3.7 2.5 11.9 0.2 3.6 15.2 6.7 1.2 12.2 0.9 11.3 0.0 17.5 15.3 2.0 2.9 4.3 1.5 9.9 10.1 5.3 0.4 0.2 0.0 1.7 0.4 0.1 2.4 34.6 11.3 0.0 4.0 0.1 1.9 6.8 4.6 0.5 2.2 2.9 1.4 4.1 17.2 1.8 5.7 3.1 87.6 15.6 0.8 7.2 1.3 5.8 20.5 11.9 13.7 18.3 13.0 17.3 19.7 16.4 18.9 17.0 18.9 15.0 15.9 19.8 4.1 6.4 10.6 609.8 19.7 7.6 20.7 30.0 46.7 12.6 41.2 31.2 10.0 38.6 17.5 27.6 58.4 42.0 12.4 6.9 78.2 19.1 45.8 14.6 7.9 7.0 7.7 17.7 276.6 4.7 8.5 10.1 18.3 19.0 5.7 25.7 14.6 23.4 20.9 30.3 450.5 12.9 22.4 10.2 7.1 163.0 19.3 12.9 12.4 337.3 8.6 19.7 6.2 1086.7 1111.0 9.7 15.0 9.8 23.8 12.0 20.7 126.6 12.4 20.7 0.0 10.7 6.2 19.1 7.5 33.7 11.2 32.7 11.5 23.0 20.1 18.8 FIP1L1 "DKFZp586K0717, FIP1" ENSG00000145216 "Factor interacting with PAPOLA and CPSF1" Q6UN15 4 53377641-53460862 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "mRNA processing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA037475, HPA058202" Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA037475: AB_10696933, HPA058202: AB_2683636" "unprognostic (3.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.60e-3)" "unprognostic (1.40e-1)" "unprognostic (7.18e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (1.51e-4)" "unprognostic (1.87e-1)" "unprognostic (9.00e-3)" "unprognostic (1.14e-2)" "unprognostic (5.48e-2)" "unprognostic (1.42e-1)" "unprognostic (4.07e-1)" "unprognostic (1.10e-1)" "unprognostic (8.66e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-1)" 19.1 15.7 5.8 14.8 5.9 31.8 17.0 11.3 8.7 18.4 1.2 14.3 11.7 17.9 12.7 15.9 16.0 11.0 13.0 4.9 9.9 13.3 13.7 14.2 20.2 4.8 5.1 22.0 9.7 16.4 9.7 21.1 4.9 12.3 15.1 17.0 14.7 11.4 25.8 17.9 14.4 15.9 4.6 14.8 14.4 31.4 7.0 29.4 14.6 11.7 23.3 17.5 16.2 8.7 43.7 29.5 51.8 32.6 36.4 31.9 63.5 52.8 64.0 45.1 35.0 43.2 37.8 79.5 42.6 47.2 44.4 26.7 55.6 37.9 55.8 27.0 31.0 60.0 25.5 40.7 51.2 95.4 53.6 31.2 35.6 51.6 49.8 42.0 32.3 47.7 71.3 34.3 34.1 33.3 88.5 44.4 35.9 53.7 28.8 79.2 22.0 36.9 33.9 34.7 40.8 41.5 37.6 40.3 65.1 47.0 25.2 33.6 33.9 44.2 39.7 39.9 67.2 43.3 27.8 100.8 38.4 59.2 84.3 45.2 23.3 51.4 32.5 25.0 38.8 34.8 33.0 32.9 31.9 32.3 36.6 32.3 28.3 50.7 37.0 46.5 45.9 33.1 5.8 5.9 11.3 8.7 4.9 9.9 4.8 5.1 4.9 4.6 7.0 8.7 36.1 25.6 25.4 47.0 50.4 38.7 46.6 41.5 30.1 41.2 24.0 25.4 14.4 21.5 34.1 27.6 18.8 58.7 54.0 26.9 37.2 45.8 10.3 37.6 51.1 33.4 36.6 29.2 78.8 34.9 52.2 41.9 29.6 41.6 49.4 40.0 28.5 21.2 33.2 77.4 78.7 27.0 32.6 19.8 24.6 15.2 66.8 32.2 32.0 60.9 41.3 48.6 29.9 137.7 91.4 36.9 33.3 53.4 40.3 36.5 25.2 23.3 44.8 30.3 39.5 38.9 46.9 118.5 87.6 31.8 34.1 86.3 49.8 56.8 29.4 38.5 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FKBP prolyl isomerase 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 892.7;tongue: 925.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 759.3;ASC TERT1: 468.5;HHSteC: 593.0;HSkMC: 718.3;hTCEpi: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm No No 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: AB_2673734" "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 400.1 92.3 18.2 70.1 26.8 26.6 160.4 19.7 32.1 86.4 20.2 110.9 11.3 97.5 63.0 130.6 104.6 78.9 93.7 16.8 20.7 108.8 144.5 92.7 166.7 22.7 23.8 122.1 200.4 227.0 52.9 28.5 23.5 85.0 37.1 25.6 61.0 49.8 892.7 114.0 135.7 81.8 17.0 105.6 129.0 41.4 22.1 229.4 97.2 925.1 80.3 108.9 109.1 26.2 40.0 17.1 73.1 109.7 759.3 468.5 1.2 21.2 1.0 13.6 31.0 29.7 6.9 195.3 19.5 4.1 11.8 0.6 44.1 93.2 32.0 77.7 41.6 84.0 14.1 41.7 593.0 53.3 8.3 718.3 368.6 23.7 220.5 14.8 80.1 38.8 91.3 77.1 144.3 25.3 222.5 99.6 18.9 8.7 12.3 97.7 19.1 95.4 60.2 23.7 27.7 16.8 17.3 19.8 4.2 15.9 108.4 62.2 178.7 19.3 17.3 2.8 29.7 34.9 42.9 243.5 6.6 102.3 7.6 57.6 105.0 70.0 64.4 92.3 78.0 9.7 90.6 68.5 107.5 12.5 133.4 96.7 85.1 45.2 46.8 32.0 37.2 158.5 18.2 26.8 19.7 32.1 16.8 20.7 22.7 23.8 23.5 17.0 22.1 26.2 180.2 12.8 11.3 23.2 42.9 17.6 59.2 20.1 37.0 1.9 32.0 20.8 131.8 74.4 14.2 5.5 0.0 1.2 102.0 14.3 23.5 0.6 9.8 55.7 76.1 57.9 20.9 102.2 25.9 7.9 0.8 97.5 18.8 79.2 38.5 54.7 117.1 225.6 35.1 0.0 2.8 35.5 34.6 384.2 44.8 22.0 160.9 192.2 7.2 66.5 110.3 4.6 44.3 16.6 26.3 2.9 19.3 218.6 66.4 49.9 157.0 27.4 18.2 22.6 144.7 188.1 106.8 14.9 19.1 37.5 21.3 0.4 128.7 2.8 39.5 22.2 FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FKBP prolyl isomerase 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 719.1;Late spermatids: 1236.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 93.4;neutrophil: 78.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 93.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA 10000 "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: AB_2679244" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (9.22e-2)" "unprognostic (2.54e-2)" "unprognostic (2.26e-1)" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "prognostic favorable (7.76e-4)" "unprognostic (8.51e-2)" "unprognostic (1.61e-1)" "unprognostic (2.97e-1)" "unprognostic (6.89e-2)" "unprognostic (1.12e-2)" "unprognostic (2.32e-1)" 206.9 161.5 426.8 79.8 423.7 272.9 197.3 359.7 645.5 235.3 332.7 311.1 85.5 188.6 59.0 238.3 198.1 85.5 244.3 427.4 395.7 194.8 233.7 187.6 97.9 427.6 405.1 263.6 167.2 109.1 312.3 91.2 406.1 249.4 33.6 51.4 200.0 115.3 202.7 185.9 159.2 62.5 381.7 193.6 189.3 378.4 423.4 86.2 205.9 105.5 52.7 228.3 222.4 437.8 196.3 139.0 106.0 201.7 106.2 165.6 266.8 155.0 163.1 116.5 160.2 133.3 259.1 111.6 245.0 191.7 77.7 104.4 65.0 216.5 31.4 136.6 316.5 105.3 175.4 162.3 183.3 105.5 220.6 217.3 204.8 104.0 65.4 216.1 121.9 213.2 222.4 254.8 102.1 329.1 190.4 313.1 216.3 174.6 200.2 197.8 88.4 387.3 154.9 126.6 117.1 213.2 108.8 87.7 197.5 77.8 104.5 299.4 143.2 143.2 130.3 282.1 120.0 194.6 118.2 130.8 321.5 166.7 130.8 18.1 14.7 93.4 14.2 15.5 13.3 10.2 14.6 16.3 11.1 9.8 11.1 12.6 78.0 8.8 19.0 11.3 15.8 30.1 426.8 423.7 359.7 645.5 427.4 395.7 427.6 405.1 406.1 381.7 423.4 437.8 115.9 9.6 1.1 35.3 115.1 95.3 164.1 118.4 68.3 64.8 110.9 107.4 2.0 115.8 58.0 101.2 14.6 246.4 107.0 287.7 248.4 178.4 412.3 65.6 59.2 92.3 205.9 719.1 32.0 126.9 234.8 126.5 80.5 64.6 52.8 125.0 99.6 66.4 237.3 99.3 33.2 156.8 126.1 184.1 145.0 1236.4 203.8 152.1 202.7 8.4 221.9 149.0 183.4 12.5 32.8 166.9 283.4 165.5 127.2 139.4 339.3 290.4 51.9 56.4 98.6 95.7 129.9 193.5 212.4 96.5 117.9 312.9 145.0 121.7 158.3 158.0 FLCN "BHD, DENND8B, MGC17998, MGC23445" ENSG00000154803 Folliculin Q8NFG4 17 17212212-17237188 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 79.2;Erythroid cells: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015158, HPA028760" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Plasma membrane" "CAB015158: AB_2231645, HPA028760: AB_10601323" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (1.53e-2)" "unprognostic (1.74e-1)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.73e-2)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (3.90e-1)" "prognostic favorable (4.49e-4)" "unprognostic (6.45e-3)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (9.71e-2)" "unprognostic (2.62e-2)" "unprognostic (1.65e-1)" 21.8 19.0 19.0 10.7 25.9 17.7 18.9 27.3 31.6 42.5 18.3 43.7 23.3 37.0 14.5 13.8 25.2 17.0 29.2 31.9 14.0 15.3 28.9 26.8 12.4 21.3 15.2 35.3 15.2 13.1 28.6 13.1 22.0 27.1 10.2 7.2 16.4 13.7 42.7 19.3 26.8 14.5 14.0 29.2 22.4 21.0 19.3 8.6 23.8 18.4 8.0 28.2 25.5 28.3 12.0 30.4 11.5 14.9 36.4 20.6 15.8 11.8 19.1 18.0 24.3 24.3 10.4 6.3 13.8 14.0 40.2 14.4 14.0 7.3 9.3 10.9 12.2 12.4 9.1 13.9 33.6 4.9 33.5 30.3 24.0 27.6 20.8 16.4 14.8 9.2 17.7 16.4 17.6 17.5 8.3 8.4 11.2 17.8 8.1 16.9 52.7 7.3 11.0 14.1 13.6 8.8 11.6 7.5 19.3 70.7 11.1 8.8 15.7 40.6 16.6 56.5 14.1 7.7 7.4 5.7 26.0 10.8 16.6 2.4 2.8 1.6 1.6 3.7 2.2 3.6 1.9 1.4 1.4 3.2 2.1 1.9 6.0 2.8 1.4 1.4 2.9 1.8 19.0 25.9 27.3 31.6 31.9 14.0 21.3 15.2 22.0 14.0 19.3 28.3 8.4 25.6 12.6 17.0 9.2 18.4 12.7 5.7 2.8 20.7 13.2 6.5 23.7 14.3 6.2 7.3 79.2 10.9 5.3 25.0 1.9 12.3 14.5 16.8 11.3 12.5 25.7 81.7 31.3 8.3 7.4 20.6 9.7 15.2 1.3 10.3 27.8 24.1 16.6 47.1 23.7 11.0 16.2 21.6 19.2 20.4 28.0 13.2 10.6 18.7 12.2 13.3 6.2 17.1 32.4 9.8 15.6 20.3 4.4 11.6 36.8 6.1 9.1 18.5 19.7 24.8 11.1 6.3 10.8 5.3 18.2 33.8 10.0 16.3 12.6 13.0 FLG ENSG00000143631 Filaggrin P20930 1 152302165-152325239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 458.2" "Cell type enriched" "Detected in some" 13 "Suprabasal keratinocytes: 44.0" "Cancer enriched" "Detected in some" 7 "melanoma: 11.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.1;NTERA-2: 3.1;TIME: 2.1;U-2 OS: 2.4;U-2197: 2.6;WM-115: 2.0" "Not detected" "Not detected" "CAB002210, HPA027505, HPA030188, HPA030189" Enhanced Enhanced "Cytoplasmic bodies" NA NA 3800000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Cytoplasmic bodies" "CAB002210: AB_563731, HPA027505: AB_10600107, HPA030188: AB_10601749, HPA030189: AB_10601999" "unprognostic (3.37e-2)" "unprognostic (3.76e-1)" "unprognostic (8.83e-2)" "unprognostic (2.96e-3)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (9.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" "unprognostic (1.45e-1)" "unprognostic (4.28e-2)" "unprognostic (4.15e-2)" "unprognostic (7.41e-3)" 0.3 0.4 0.7 0.1 0.3 0.1 15.7 0.3 0.4 6.5 0.0 0.2 0.0 0.5 0.0 12.0 0.4 0.1 0.4 0.3 1.4 0.4 0.2 0.2 0.0 1.6 0.9 0.9 0.4 0.0 0.2 0.0 1.2 0.2 0.0 0.2 2.7 0.0 1.8 458.2 0.1 0.0 0.8 0.1 0.2 0.3 0.8 0.5 0.3 0.0 0.5 0.1 4.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.0 10.1 0.0 0.0 0.0 1.1 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 2.1 0.8 2.4 2.6 1.9 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.3 0.4 0.3 1.4 1.6 0.9 1.2 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.0 0.0 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.0 44.0 0.0 0.1 0.1 0.0 0.0 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FLT3 "CD135, FLK2, STK1" ENSG00000122025 "Fms related receptor tyrosine kinase 3" P36888 13 28003274-28100592 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.3;brain: 4.9;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 24.4;Inhibitory neurons: 59.9;Kupffer cells: 29.1;Langerhans cells: 21.4;Macrophages: 16.9;monocytes: 39.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.8" "Region enhanced" "Detected in some" "cerebellum: 4.9" "Group enriched" "Detected in many" 13 "myeloid DC: 68.7;plasmacytoid DC: 26.2" "Lineage enriched" "Detected in many" 19 "dendritic cells: 68.7" "Group enriched" "Detected in some" 11 "REH: 42.5;THP-1: 26.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047539 Approved "Endoplasmic reticulum" NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 14: REH - Unknown function" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "HPA047539: AB_2680080" "unprognostic (2.19e-3)" "unprognostic (3.16e-3)" "unprognostic (6.54e-3)" "unprognostic (9.96e-2)" "unprognostic (3.88e-1)" "unprognostic (3.96e-7)" "unprognostic (7.99e-3)" "unprognostic (1.65e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" "unprognostic (3.65e-1)" "unprognostic (3.91e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" 0.5 0.1 0.3 3.0 0.2 5.3 1.5 4.9 0.8 0.5 0.1 0.7 0.3 0.2 0.1 0.6 0.4 1.6 0.1 0.2 0.5 1.5 0.5 0.7 6.5 1.3 0.9 0.1 2.8 0.0 0.0 0.0 1.7 0.1 0.8 0.0 0.4 0.2 0.0 0.7 1.6 0.8 0.8 5.7 0.6 0.6 0.8 4.7 0.1 0.3 3.6 1.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 0.6 0.0 0.0 42.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 3.6 3.4 0.0 0.8 0.0 0.2 0.0 0.0 68.7 0.0 0.0 0.0 0.1 2.0 0.0 26.2 0.0 2.7 0.3 0.2 4.9 0.8 0.2 0.5 1.3 0.9 1.7 0.8 0.8 0.8 0.0 0.0 0.0 2.3 1.5 0.3 0.0 0.0 0.0 0.0 1.5 1.0 0.4 1.5 0.0 0.0 0.0 0.0 24.4 0.0 0.0 2.7 3.7 0.3 0.1 0.2 0.0 8.2 7.4 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.7 0.1 0.5 0.0 59.9 0.0 0.0 29.1 21.4 2.3 0.0 16.9 1.8 1.9 39.5 0.0 0.0 1.5 4.2 0.1 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.0 0.6 0.0 1.7 0.0 0.0 0.0 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 683.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 64.2;Cholangiocytes: 133.0;Hepatocytes: 265.4;Proximal enterocytes: 108.8;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "Hep G2: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 3.1 5.7 2.0 5.1 2.9 2.0 46.1 3.9 2.8 7.8 0.5 41.3 71.3 2.8 6.9 1.2 3.6 15.8 3.1 2.1 2.4 51.5 683.3 27.1 4.0 4.2 2.9 4.1 48.1 68.3 6.7 2.4 4.8 9.7 46.6 0.9 32.7 4.0 0.8 11.6 73.9 3.5 3.2 4.0 120.1 5.2 3.1 1.1 2.0 1.4 2.5 3.9 1.5 5.6 0.1 1.1 0.6 0.1 2.8 0.8 0.9 0.7 0.5 0.3 0.8 0.7 2.4 0.4 0.8 0.8 0.2 0.4 0.0 0.0 0.0 1.4 0.2 1.6 0.1 41.7 0.9 1.4 9.0 1.3 0.2 0.4 0.0 0.4 0.6 0.2 0.1 0.1 1.5 1.4 0.2 0.7 2.8 5.3 0.8 0.4 0.5 0.4 3.4 0.6 0.5 0.3 0.9 2.8 1.3 1.3 2.1 10.4 1.1 0.0 0.3 0.9 0.0 0.3 0.0 0.3 1.1 0.5 0.3 7.0 12.9 4.1 2.0 5.9 0.3 4.7 0.5 0.6 5.4 8.5 0.3 1.3 1.3 1.2 1.8 2.5 1.6 3.9 2.0 2.9 3.9 2.8 2.1 2.4 4.2 2.9 4.8 3.2 3.1 5.6 2.8 9.6 64.2 11.1 6.4 1.7 3.9 0.9 1.8 2.0 17.5 6.7 1.9 133.0 10.4 14.7 0.0 1.5 1.7 60.8 7.9 7.5 7.7 2.5 1.8 2.7 6.7 4.8 8.2 5.9 1.1 2.9 24.5 6.1 5.7 9.8 5.0 265.4 4.0 3.3 6.4 34.4 4.1 10.0 2.3 4.5 2.8 4.6 28.4 10.3 5.3 0.2 4.1 10.1 17.5 7.0 29.0 1.5 0.4 5.6 108.8 69.2 18.1 1.3 0.0 2.2 1.0 5.9 0.9 1.3 1.6 1.4 2.6 6.6 20.7 6.4 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49145092-49208638 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 266.4;prostate: 76.0" "Cell type enriched" "Detected in some" 8 "Oligodendrocytes: 367.6" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;RPMI-8226: 1.7;SK-BR-3: 1.8;TIME: 1.3;WM-115: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favorable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" 1.8 1.1 17.3 0.9 37.3 0.7 4.8 27.1 27.7 1.9 7.9 0.7 266.4 1.7 0.9 1.5 3.5 10.2 0.5 18.3 22.4 13.5 35.5 1.3 0.9 32.7 28.4 1.0 0.3 0.2 0.0 0.3 31.5 76.0 0.5 4.0 52.8 0.6 0.2 1.7 82.9 1.0 24.1 2.4 1.1 0.8 31.1 0.1 1.0 0.2 0.6 1.4 0.3 59.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.1 2.3 0.2 0.0 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.1 1.7 0.0 0.0 0.2 0.7 0.0 1.8 0.3 0.2 0.3 0.0 1.3 0.1 0.9 0.2 0.1 0.0 0.2 0.0 0.0 0.4 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.3 37.3 27.1 27.7 18.3 22.4 32.7 28.4 31.5 24.1 31.1 59.3 0.5 0.0 0.6 0.0 0.0 0.3 0.7 0.1 0.6 0.0 8.2 7.0 0.3 0.0 1.9 0.0 0.0 0.0 0.5 0.0 7.9 0.0 5.2 2.1 0.5 5.0 0.0 0.0 0.5 0.0 0.0 2.2 0.0 2.8 0.0 0.0 2.9 25.9 0.1 0.0 1.0 1.1 0.0 0.3 0.0 1.4 1.5 0.2 3.6 1.0 0.0 17.4 0.0 0.0 367.6 0.0 1.2 0.4 0.0 43.0 0.8 32.4 0.1 0.6 0.0 0.0 0.4 1.1 1.5 1.5 0.9 0.0 0.2 0.5 0.2 0.6 FOS "AP-1, c-fos" ENSG00000170345 "Fos proto-oncogene, AP-1 transcription factor subunit" P01100 14 75278826-75282230 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 504.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 504.8" "Cell line enhanced" "Detected in many" "hTCEpi: 453.1;OE19: 170.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebellum: 80.9;spinal cord: 235.3" HPA018531 Approved Supported Nucleoplasm Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA018531: AB_1846576" "unprognostic (1.18e-2)" "unprognostic (8.70e-2)" "unprognostic (1.61e-1)" "unprognostic (3.80e-1)" "unprognostic (3.08e-2)" "unprognostic (4.82e-2)" "unprognostic (2.09e-1)" "unprognostic (3.30e-1)" "unprognostic (9.55e-3)" "unprognostic (4.20e-3)" "unprognostic (1.04e-1)" "prognostic favorable (7.81e-4)" "unprognostic (3.20e-2)" "unprognostic (1.52e-2)" "unprognostic (3.22e-1)" "unprognostic (1.43e-1)" "unprognostic (2.66e-2)" 1136.1 735.7 62.9 576.0 87.2 2270.6 477.4 184.8 113.1 700.5 111.5 479.5 235.3 410.4 58.4 1250.8 1777.3 1160.0 513.1 58.9 190.7 266.1 308.8 486.9 449.9 145.1 84.0 1188.7 298.4 264.7 452.3 417.4 92.0 791.1 627.4 233.3 555.6 462.3 99.1 1645.4 584.5 964.3 100.6 178.0 525.6 87.2 104.4 424.2 1007.6 1014.2 26.8 946.5 346.6 121.7 2.2 1.4 7.1 10.4 59.9 18.3 42.1 6.4 2.4 4.5 3.2 4.4 12.6 0.6 1.8 43.5 42.6 3.0 3.6 74.7 1.1 1.2 1.1 1.0 21.9 1.9 27.6 2.6 42.8 44.3 453.1 3.9 27.4 6.2 2.7 9.2 2.0 19.7 1.2 26.1 0.9 12.9 7.4 170.9 2.5 2.0 1.4 23.8 18.8 20.4 52.4 3.6 9.8 85.9 39.8 21.8 1.4 9.2 6.3 0.4 5.7 3.7 2.0 52.4 61.2 9.6 2.9 8.0 5.7 38.3 81.0 89.5 0.3 20.1 0.4 0.3 0.2 0.7 69.6 0.2 0.2 0.1 504.8 4.6 2.5 1.5 0.4 27.7 62.9 87.2 184.8 113.1 58.9 190.7 145.1 84.0 92.0 100.6 104.4 121.7 3911.0 1102.6 1859.4 137.1 1015.9 859.7 1644.7 1577.5 4336.7 106.1 3184.1 2874.6 1027.6 1416.9 752.7 191.3 129.3 1506.7 1323.5 1648.6 17.6 690.9 17.4 1834.4 3720.3 1624.0 1628.0 290.5 4.9 528.1 2694.6 4146.8 2049.5 3656.5 1630.6 751.3 1317.2 207.2 1693.8 35.3 3.0 1967.2 793.5 2600.2 1540.4 53.5 943.8 2910.7 855.6 58.1 269.5 1119.5 10.3 6.0 1.8 383.5 1507.8 178.3 1256.1 1115.7 1675.1 20.0 354.4 406.9 1209.6 3390.9 2705.7 10.0 10.5 2438.0 1092.4 2283.3 1497.0 417.4 1366.2 298.4 FOSL1 fra-1 ENSG00000175592 "FOS like 1, AP-1 transcription factor subunit" P15407 11 65892049-65900573 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 56.4;urinary bladder: 84.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 338.0;Basal prostatic cells: 398.5;Basal squamous epithelial cells: 281.1;Prostatic glandular cells: 196.9;Squamous epithelial cells: 210.4;Suprabasal keratinocytes: 339.5;Urothelial cells: 456.4" "Cancer enhanced" "Detected in all" "head and neck cancer: 51.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "PC-3: 829.4;U-2197: 520.1;WM-115: 1123.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB004396, HPA030728" Enhanced Supported Nucleoplasm NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB004396: AB_627632, HPA030728: " "unprognostic (2.88e-2)" "unprognostic (1.56e-1)" "unprognostic (9.46e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.80e-4)" "prognostic unfavorable (2.05e-4)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (9.26e-5)" "unprognostic (7.85e-2)" "prognostic unfavorable (6.40e-6)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (2.28e-1)" "unprognostic (2.82e-2)" 56.4 11.2 1.2 7.7 1.3 26.8 10.5 2.2 4.3 6.0 1.0 7.4 1.0 3.5 0.1 48.9 8.5 29.6 11.9 1.6 1.7 12.6 5.6 16.7 0.3 1.9 1.4 1.7 12.9 0.5 4.8 2.7 2.1 6.4 1.9 0.6 11.0 0.8 4.1 25.2 5.5 4.7 1.0 1.7 21.0 0.9 1.9 2.7 5.3 0.3 2.1 84.3 13.8 1.0 324.3 43.8 5.4 20.4 45.7 44.4 45.0 288.5 257.2 239.7 131.7 14.2 252.6 0.5 65.1 199.7 379.6 60.6 19.6 227.4 210.8 9.7 0.7 20.6 4.5 34.9 57.0 13.3 6.9 18.8 23.1 191.1 297.1 117.9 80.4 0.2 48.8 1.7 320.9 12.3 0.3 26.5 21.5 27.0 829.4 1.5 25.7 1.3 116.7 20.4 0.4 0.5 18.2 0.8 229.0 13.0 1.0 12.1 200.6 282.5 62.7 520.1 423.8 0.3 1.4 0.9 389.7 4.9 1123.6 0.0 0.8 0.0 0.1 0.5 0.0 0.0 0.2 0.1 3.4 0.0 0.2 0.0 0.5 0.0 0.3 0.4 0.0 0.5 1.2 1.3 2.2 4.3 1.6 1.7 1.9 1.4 2.1 1.0 1.9 1.0 15.2 6.4 4.4 0.3 2.0 338.0 398.5 56.2 281.1 0.0 27.6 12.2 1.0 4.3 26.2 0.0 0.0 1.3 4.3 11.8 0.0 25.1 0.3 24.4 12.2 30.1 11.3 0.8 0.1 3.5 4.3 45.8 74.9 56.3 9.5 0.3 6.1 0.4 1.9 0.0 0.1 6.8 10.2 1.0 46.6 0.0 0.3 15.5 44.4 1.0 1.1 0.1 0.0 0.5 0.2 39.0 11.1 0.0 6.2 196.9 1.2 0.2 10.7 0.0 0.0 32.4 26.1 0.4 0.7 210.4 339.5 17.6 6.8 0.1 4.2 456.4 FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589552-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 74.7;stomach 1: 28.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 113.8;Basal squamous epithelial cells: 76.8;Breast glandular cells: 87.9;Enteroendocrine cells: 84.6;Prostatic glandular cells: 89.8;Respiratory ciliated cells: 66.7;Urothelial cells: 154.5" "Group enriched" "Detected in many" 5 "breast cancer: 80.0;prostate cancer: 127.0" "Region enriched" "Detected in single" 5 "midbrain: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 48.9;MCF7: 105.3;PC-3: 69.5;RT4: 96.7;SK-BR-3: 97.0;T-47d: 135.9" "Region enhanced" "Detected in some" "midbrain: 1.1" "Region enriched" "Detected in single" 6 "midbrain: 5.4" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "CAB011595: AB_2104842, HPA050505: AB_2681148" "unprognostic (1.61e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (3.01e-1)" "unprognostic (1.54e-2)" "unprognostic (6.30e-2)" "unprognostic (0.00e+0)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.69e-2)" "prognostic favorable (1.00e-4)" 0.2 0.1 0.0 1.6 0.0 0.0 22.3 0.0 0.0 1.5 0.0 12.4 8.4 0.1 0.6 11.9 2.4 2.3 0.0 0.0 0.3 0.1 26.9 7.5 0.0 0.1 3.5 0.0 0.5 0.0 0.7 0.0 0.2 74.7 10.4 0.0 19.3 0.3 0.0 1.3 4.8 0.2 0.2 0.0 28.0 0.4 0.7 0.0 0.0 0.0 2.3 20.5 4.4 0.0 4.9 4.4 0.0 2.8 0.0 0.0 0.5 0.0 0.4 0.0 0.0 21.3 2.7 0.0 1.4 0.0 0.1 23.4 13.2 3.3 0.1 0.0 23.4 0.0 4.1 48.9 0.0 0.0 0.2 0.0 0.7 0.0 0.4 1.9 0.0 0.4 0.9 0.0 0.0 105.3 0.1 0.3 0.0 32.0 69.5 0.0 1.1 0.4 9.9 96.7 11.8 0.0 4.8 97.0 0.0 0.0 135.9 0.4 0.0 0.9 0.1 0.4 3.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 3.5 0.2 0.2 0.7 0.0 0.3 28.9 43.5 0.0 0.1 1.0 113.8 47.8 76.8 0.0 87.9 34.8 1.3 30.0 52.3 3.7 0.0 0.0 0.5 27.5 0.0 1.5 0.4 2.7 0.2 1.2 84.6 0.0 0.0 2.4 0.0 1.0 35.7 4.4 2.5 0.0 1.1 31.7 0.0 0.0 0.0 34.9 42.7 0.9 0.3 0.9 0.0 0.7 3.6 0.0 1.0 0.0 0.0 0.0 0.0 4.3 27.2 0.0 1.2 89.8 4.9 0.0 66.7 0.0 0.0 0.0 2.3 0.9 1.2 62.9 0.1 0.0 1.4 0.1 27.9 154.5 FOXA2 HNF3B ENSG00000125798 "Forkhead box A2" Q9Y261 20 22580998-22585455 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 36.2;pancreas: 26.6;stomach 1: 31.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 96.1;Alveolar cells type 2: 78.0;Cholangiocytes: 47.1;Exocrine glandular cells: 37.0;Gastric mucus-secreting cells: 37.8;Hepatocytes: 63.7;Intestinal goblet cells: 87.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 17.5;HBEC3-KT: 19.3;Hep G2: 28.8;hTERT-HME1: 12.6;OE19: 22.7;PC-3: 24.7;SCLC-21H: 42.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "midbrain: 3.9" "CAB001388, HPA066846" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Cell Junctions" "CAB001388: AB_2262810, HPA066846: AB_2685736" "unprognostic (1.19e-1)" "unprognostic (1.99e-1)" "prognostic favorable (7.57e-6)" "unprognostic (6.82e-2)" "unprognostic (1.50e-6)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "prognostic favorable (6.28e-4)" "prognostic favorable (2.34e-4)" "unprognostic (3.18e-1)" "unprognostic (2.55e-15)" "unprognostic (2.50e-2)" "unprognostic (1.68e-1)" "unprognostic (7.12e-2)" "unprognostic (3.93e-3)" 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 14.2 0.0 7.3 3.7 2.1 0.0 0.1 4.3 4.0 0.0 0.0 0.0 0.2 36.2 13.7 0.0 0.0 2.5 0.0 26.6 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 31.1 0.4 0.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.6 0.0 0.3 0.0 0.1 0.0 0.0 19.3 0.0 0.0 1.2 0.0 0.0 28.8 0.0 0.0 0.0 0.0 10.3 0.0 12.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 22.7 24.7 0.0 0.0 0.0 0.8 0.0 42.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.5 0.0 0.0 96.1 78.0 0.0 0.1 0.0 0.8 0.5 0.0 0.0 0.1 0.3 0.3 47.1 12.5 0.0 0.0 0.0 0.0 21.7 0.0 25.6 0.1 30.8 2.6 0.1 28.1 0.0 0.0 37.0 0.0 0.3 37.8 27.1 4.5 0.0 0.7 63.7 0.0 0.0 0.0 87.2 6.1 1.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 24.4 6.8 0.0 0.2 1.0 1.0 0.0 10.0 0.0 0.0 0.0 0.2 4.1 0.2 0.0 0.0 0.0 1.0 0.0 28.7 0.1 FOXJ1 "FKHL13, HFH-4, HFH4" ENSG00000129654 "Forkhead box J1" Q92949 17 76136333-76141245 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 43.4;choroid plexus: 80.1;fallopian tube: 53.2" "Group enriched" "Detected in many" 8 "Endometrial ciliated cells: 234.7;Respiratory ciliated cells: 124.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 73.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 29.9;CAPAN-2: 25.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 43.1" HPA005714 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA005714: AB_1078902" "prognostic favorable (9.39e-4)" "unprognostic (4.97e-3)" "unprognostic (1.22e-1)" "unprognostic (2.77e-3)" "unprognostic (1.19e-1)" "unprognostic (2.54e-3)" "unprognostic (1.71e-3)" "unprognostic (6.15e-2)" "unprognostic (1.00e-2)" "unprognostic (7.84e-3)" "unprognostic (1.43e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.03e-5)" "unprognostic (7.49e-2)" "unprognostic (1.94e-1)" "unprognostic (2.27e-1)" "unprognostic (1.91e-1)" 0.0 0.0 12.2 0.1 12.7 0.3 0.0 13.0 10.8 6.6 80.1 0.6 0.3 2.2 0.5 0.3 53.2 0.0 0.0 14.6 18.3 3.4 0.0 10.4 0.0 36.7 43.4 0.2 0.9 0.0 2.2 0.0 25.2 0.5 0.2 0.4 0.1 2.5 0.4 0.8 0.2 0.0 23.3 0.0 0.5 16.7 22.6 0.2 3.0 0.0 0.0 0.9 0.1 14.9 0.0 0.5 1.7 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 3.1 25.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 12.2 12.7 13.0 10.8 14.6 18.3 36.7 43.4 25.2 23.3 22.6 14.9 2.2 9.6 3.1 1.0 2.3 0.8 1.0 4.4 0.0 0.4 5.6 4.2 0.9 1.5 12.0 9.2 4.2 0.2 4.8 1.0 0.0 0.6 21.4 234.7 4.5 0.7 1.8 3.0 0.0 0.0 0.6 1.6 4.1 10.7 1.3 0.1 0.4 0.0 0.1 0.0 0.1 3.2 4.1 0.6 0.0 19.1 0.3 1.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.8 0.4 1.3 0.5 0.2 3.5 124.0 8.7 0.0 1.8 3.5 20.7 2.0 0.8 0.9 0.3 3.5 1.1 2.3 0.7 FOXL2 "BPES, BPES1" ENSG00000183770 "Forkhead box L2" P58012 3 138944224-138947137 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 12.8;ovary: 44.8;parathyroid gland: 12.5" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 208.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 4.9;fHDF/TERT166: 5.6;HEL: 8.1;hTCEpi: 7.1;K-562: 8.4;SiHa: 5.6;THP-1: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA069613 Enhanced Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA069613: AB_2686160" "unprognostic (1.46e-1)" "unprognostic (3.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.05e-1)" "unprognostic (5.16e-4)" "unprognostic (3.55e-2)" "unprognostic (2.35e-3)" "unprognostic (5.08e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-1)" "unprognostic (9.63e-8)" "unprognostic (2.16e-2)" "unprognostic (4.65e-1)" "unprognostic (2.90e-2)" "unprognostic (1.61e-2)" 0.0 2.6 1.0 0.0 0.8 0.0 0.0 0.6 0.8 12.8 0.3 0.0 0.0 7.3 0.4 0.0 11.9 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.8 0.8 44.8 0.1 12.5 10.0 0.1 0.8 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.8 0.0 0.0 0.7 1.2 0.0 0.0 0.1 0.0 0.0 2.1 0.7 4.9 1.8 0.2 3.4 0.0 0.0 1.4 0.1 0.0 0.4 0.0 0.0 0.3 0.0 2.2 5.6 0.2 1.1 0.0 0.0 0.1 0.0 0.0 8.1 0.9 0.0 0.0 0.1 0.0 0.0 7.1 0.0 0.0 1.1 0.0 0.0 8.4 0.0 2.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.6 0.0 0.0 0.3 0.0 5.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.6 0.8 0.6 0.6 0.8 0.8 0.8 0.8 1.2 0.7 0.2 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 41.8 1.6 0.0 0.0 0.0 0.2 0.3 20.9 0.0 1.0 0.0 208.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 6.2 1.8 1.4 0.0 1.0 0.0 0.3 48.4 0.0 0.0 FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 32.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Erythroid cells: 18.7;Extravillous trophoblasts: 18.2;Late spermatids: 25.5;Plasma cells: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (3.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.95e-6)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.01e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (6.09e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" 1.9 1.1 0.4 9.4 0.5 25.0 1.8 0.8 0.8 1.7 0.2 10.5 9.7 1.7 0.2 11.1 0.8 1.5 0.5 0.8 0.3 0.7 1.2 1.8 11.3 0.4 0.9 0.3 0.4 0.4 0.1 6.1 0.6 0.7 12.5 1.1 1.9 0.8 0.6 6.4 8.8 7.5 0.1 3.1 5.2 21.4 1.0 32.2 0.9 0.3 15.2 3.0 3.2 0.6 133.0 129.5 101.3 92.2 14.2 19.0 129.2 84.0 80.4 165.2 147.2 166.9 114.8 84.5 17.7 119.8 188.5 100.2 153.1 76.1 160.0 159.8 80.3 94.7 121.6 71.6 2.0 79.2 75.0 9.9 8.3 154.4 106.1 39.1 117.8 96.8 55.6 184.9 130.5 122.6 108.3 36.8 225.6 136.1 95.4 77.3 149.8 44.1 38.1 82.7 56.3 89.1 106.7 90.4 46.6 189.4 87.1 87.8 48.0 134.3 200.5 160.4 300.4 24.7 44.3 122.1 63.1 74.3 147.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.8 0.8 0.8 0.3 0.4 0.9 0.6 0.1 1.0 0.6 0.1 0.0 1.3 0.7 2.4 2.9 1.3 1.0 1.2 2.0 1.7 1.3 0.5 1.5 0.8 1.8 4.2 7.1 0.8 6.6 1.9 0.2 22.4 1.2 2.1 2.5 0.0 18.7 1.1 0.0 18.2 3.2 10.2 2.4 0.0 15.4 3.6 0.8 9.1 5.0 0.6 7.5 2.0 4.2 1.2 25.5 0.9 2.4 0.0 0.0 1.1 0.6 1.0 0.5 1.0 0.3 0.3 0.7 19.9 1.0 1.4 0.4 0.2 4.0 0.0 1.2 3.0 15.0 9.9 10.2 1.4 1.9 3.3 0.9 12.9 1.9 FOXO1 "FKH1, FKHR, FOXO1A" ENSG00000150907 "Forkhead box O1" Q12778 13 40555667-40666641 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Autophagy, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.0" "Cell type enhanced" "Detected in many" "Astrocytes: 177.3;Endometrial stromal cells: 161.0;Granulosa cells: 177.9;Oligodendrocytes: 131.5;Skeletal myocytes: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 40.4;Daudi: 45.3;HSkMC: 53.6;U-698: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001252, CAB022326" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022326: , HPA001252: AB_1078906" "unprognostic (4.72e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-2)" "unprognostic (4.35e-1)" "unprognostic (2.42e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.74e-4)" "unprognostic (6.35e-2)" "unprognostic (1.60e-1)" "unprognostic (8.65e-3)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.33e-5)" "unprognostic (1.93e-1)" "unprognostic (5.44e-1)" "unprognostic (9.09e-2)" "unprognostic (9.63e-2)" 43.2 9.7 11.2 13.1 16.1 13.8 27.6 10.0 10.9 19.1 16.7 13.8 5.0 39.1 6.5 13.0 25.7 14.5 13.9 9.1 11.8 11.8 38.5 16.8 23.8 14.1 12.7 65.6 16.5 5.3 7.6 11.2 12.7 10.1 9.6 3.9 9.8 10.1 91.0 18.0 10.9 27.0 10.5 15.7 9.5 8.9 11.3 11.6 19.0 22.2 24.0 13.4 17.4 14.3 0.7 1.7 12.4 0.3 40.4 7.9 11.8 1.8 2.5 0.5 0.3 3.7 3.0 45.3 8.1 1.2 1.9 10.7 9.8 5.3 0.7 20.9 10.1 0.0 1.4 10.1 19.1 0.4 1.2 53.6 35.5 0.2 6.7 2.5 31.7 3.3 0.9 14.0 3.1 1.6 0.1 0.6 18.0 6.2 3.1 32.4 14.3 3.6 22.9 5.8 2.6 0.6 1.6 8.5 1.8 14.1 1.5 1.1 18.6 0.3 2.3 0.1 1.1 7.9 3.3 57.8 1.2 2.1 5.7 0.9 0.6 0.5 1.3 0.8 1.8 3.7 3.6 2.2 0.4 5.8 5.5 4.3 2.5 1.4 1.4 0.0 5.1 1.0 11.2 16.1 10.0 10.9 9.1 11.8 14.1 12.7 12.7 10.5 11.3 14.3 57.9 0.0 4.4 177.3 29.3 29.3 19.1 13.0 27.9 3.7 12.9 17.3 11.5 10.0 9.9 9.2 12.5 0.5 22.9 27.5 0.0 11.1 7.2 55.4 161.0 50.2 52.2 3.2 7.4 18.0 3.8 40.8 18.8 118.8 1.3 177.9 84.3 47.9 6.5 5.0 23.0 21.0 8.2 14.6 26.9 4.0 18.6 18.6 12.4 117.1 18.4 5.5 8.2 47.3 131.5 19.5 16.3 13.2 32.9 10.1 7.7 8.8 9.2 9.8 6.6 131.7 31.3 6.4 14.6 25.3 26.7 0.8 40.3 64.0 12.5 13.0 FOXO3 "AF6q21, FKHRL1, FOXO2, FOXO3A" ENSG00000118689 "Forkhead box O3" O43524 6 108559835-108684774 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 94.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004074, HPA063104" Supported Enhanced Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB004074: AB_2106672, HPA063104: AB_2684941" "unprognostic (3.42e-2)" "unprognostic (3.76e-2)" "unprognostic (4.28e-2)" "unprognostic (1.96e-2)" "unprognostic (6.68e-2)" "unprognostic (4.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.73e-1)" "unprognostic (3.81e-2)" "unprognostic (5.18e-2)" "unprognostic (1.98e-2)" "unprognostic (1.75e-1)" "unprognostic (2.54e-2)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "unprognostic (5.81e-2)" "unprognostic (5.68e-2)" 46.7 11.4 14.7 13.4 15.1 68.5 43.1 34.0 19.6 28.1 19.3 21.7 12.4 23.5 15.3 35.4 25.4 28.2 18.6 14.3 9.8 16.3 23.1 30.3 12.8 17.4 15.5 43.0 86.9 30.2 8.6 21.3 13.3 20.0 17.0 28.7 25.1 11.5 84.1 30.6 16.9 21.1 11.5 18.8 22.2 11.9 17.1 18.5 18.0 51.4 15.8 23.2 27.4 17.0 21.6 6.8 9.1 20.4 41.2 48.4 16.1 17.0 17.7 13.5 19.9 11.9 19.5 11.7 14.8 20.0 22.3 15.0 12.1 20.8 20.4 12.9 18.3 32.5 6.2 9.8 47.4 8.6 24.8 56.0 43.2 29.3 40.4 19.8 10.3 10.2 21.8 94.5 26.9 12.2 9.4 12.6 6.1 10.1 11.6 12.1 32.4 48.7 30.7 16.5 23.4 59.9 12.7 11.8 16.6 18.1 12.1 27.7 18.3 24.9 12.9 13.8 20.6 0.9 16.8 13.5 13.4 16.2 16.4 7.8 2.8 6.1 3.2 1.5 3.8 0.8 1.7 2.6 1.7 1.7 1.4 2.0 15.6 3.7 5.3 2.7 1.9 1.1 14.7 15.1 34.0 19.6 14.3 9.8 17.4 15.5 13.3 11.5 17.1 17.0 88.2 44.8 46.0 112.6 41.2 67.7 73.3 34.4 91.6 63.4 64.1 46.9 31.6 71.4 44.4 25.8 70.9 25.4 41.4 86.9 17.6 50.4 19.9 91.2 41.8 55.6 66.9 246.9 102.7 30.9 36.9 105.8 46.9 105.6 15.2 46.2 84.6 77.7 46.4 52.2 99.9 55.0 20.3 85.2 83.3 17.7 106.6 96.6 56.9 160.2 55.9 78.9 22.6 108.6 133.2 73.3 44.2 100.4 83.3 122.2 28.3 21.1 57.7 68.6 32.9 236.6 81.6 9.1 17.8 61.1 46.5 41.2 37.6 30.6 34.5 184.2 FOXO4 "AFX1, MLLT7" ENSG00000184481 "Forkhead box O4" P98177 X 71095851-71103532 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 116.5" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 260.7;Syncytiotrophoblasts: 307.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 6 "BEWO: 159.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039560, HPA040232" Enhanced Supported "Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA039560: AB_2676572, HPA040232: AB_2676894" "unprognostic (4.64e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (4.79e-2)" "prognostic favorable (4.61e-4)" "unprognostic (1.09e-1)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (7.18e-2)" "unprognostic (2.13e-2)" "unprognostic (8.16e-2)" "prognostic favorable (3.46e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-3)" 15.8 33.6 73.9 6.5 80.6 22.0 13.9 58.9 68.7 12.9 43.1 22.1 11.0 17.1 16.4 12.0 17.6 9.4 18.2 58.3 61.8 9.4 7.2 10.0 7.1 71.7 70.5 23.2 12.7 16.0 7.0 116.5 65.3 14.3 8.0 7.5 16.7 19.2 67.3 15.1 14.3 8.2 62.3 13.9 13.5 17.3 68.8 14.5 10.9 49.4 6.4 17.2 13.2 81.6 4.6 1.2 3.4 4.9 7.9 5.7 159.1 3.4 3.9 1.8 4.5 3.3 6.5 5.9 4.7 4.5 1.9 2.1 8.8 4.2 2.2 6.0 13.7 8.5 27.3 5.0 4.8 4.9 6.9 5.1 9.7 1.7 1.1 7.9 4.7 8.4 17.5 12.5 0.8 0.9 8.6 8.0 16.9 11.5 5.6 5.7 8.5 10.1 3.0 2.6 2.8 7.3 7.1 1.1 8.3 24.7 1.9 3.1 4.3 1.1 2.3 8.3 0.8 7.7 4.3 1.0 4.3 13.6 1.3 0.0 0.1 1.0 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.2 0.1 0.4 0.9 0.2 0.1 0.0 0.3 0.3 73.9 80.6 58.9 68.7 58.3 61.8 71.7 70.5 65.3 62.3 68.8 81.6 10.1 0.0 2.7 0.3 3.8 5.4 3.9 0.6 9.1 1.3 8.2 7.7 6.6 5.7 1.5 9.2 4.2 260.7 6.5 20.6 1.9 2.7 0.3 3.2 2.8 6.1 6.1 17.7 0.8 3.0 24.3 4.0 5.1 3.1 2.5 3.1 5.0 2.9 22.3 1.7 0.8 12.2 0.0 7.1 5.2 1.4 6.8 4.4 3.6 1.0 2.6 4.4 4.1 1.0 2.2 3.1 8.6 15.4 7.3 2.5 17.1 4.4 1.5 0.8 6.6 4.0 3.8 0.6 0.4 6.0 3.4 307.8 7.0 48.3 7.4 3.8 FOXP1 "12CC4, hFKH1B, HSPC215, QRF1" ENSG00000114861 "Forkhead box P1" Q9H334 3 70954708-71583989 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 41.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTEC/SVTERT24-B: 95.0" "Low region specificity" "Detected in all" "HPA003876, CAB011501" Supported Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB011501: AB_732428, HPA003876: AB_1078907" "unprognostic (2.31e-1)" "unprognostic (4.35e-3)" "unprognostic (2.09e-2)" "unprognostic (3.54e-2)" "unprognostic (2.69e-1)" "unprognostic (2.81e-3)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (2.03e-1)" "unprognostic (4.38e-3)" "unprognostic (3.40e-1)" "unprognostic (6.14e-2)" "unprognostic (1.05e-1)" "unprognostic (8.65e-2)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" 16.5 3.8 5.0 20.3 41.1 38.5 14.5 0.3 12.5 11.2 9.9 28.7 12.2 15.3 6.5 23.0 14.3 21.0 12.7 7.8 0.0 7.0 13.0 22.9 22.2 3.1 6.7 32.4 16.8 6.5 9.1 13.7 0.9 21.2 23.4 2.6 29.7 9.6 8.2 10.9 15.3 22.7 0.1 17.8 20.6 14.4 6.6 26.3 14.5 11.1 25.4 21.6 14.2 8.1 9.6 8.0 16.8 13.2 8.4 21.3 8.2 26.3 30.9 22.0 17.4 51.9 11.2 31.1 4.3 12.9 17.6 6.9 31.0 22.8 40.3 7.8 11.7 13.0 17.0 52.7 20.5 25.7 31.6 21.7 10.3 95.0 42.1 18.3 36.6 15.4 13.6 36.7 10.8 42.6 11.9 9.3 19.7 7.2 39.9 38.0 30.7 4.7 18.8 30.1 14.5 27.6 32.6 7.7 1.9 15.9 5.6 21.9 47.7 34.9 14.3 48.9 42.2 9.0 7.1 41.8 22.5 35.7 7.5 46.9 15.3 15.2 18.3 13.1 19.4 58.1 38.7 22.6 13.0 62.2 60.8 40.0 27.0 22.2 25.3 21.7 35.9 28.8 5.0 41.1 0.3 12.5 7.8 0.0 3.1 6.7 0.9 0.1 6.6 8.1 158.8 73.7 121.3 130.9 266.5 183.0 170.6 58.2 176.4 30.3 98.5 115.1 42.1 148.7 72.0 33.1 18.8 47.2 122.9 118.1 31.3 79.0 156.0 116.3 48.2 184.9 271.6 111.5 391.0 95.1 12.6 90.4 95.8 128.0 219.8 117.7 184.9 72.3 49.5 6.7 139.9 231.2 154.6 117.6 209.0 89.6 42.0 101.3 37.4 414.1 120.3 15.5 116.4 184.5 286.4 124.8 102.8 24.8 66.0 178.8 91.7 19.4 83.7 42.8 92.1 102.9 119.4 13.7 33.6 111.5 101.4 52.4 168.1 33.1 157.2 146.3 FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 107.2;urinary bladder: 53.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.4;Basal respiratory cells: 24.9;Collecting duct cells: 40.5;Gastric mucus-secreting cells: 67.2;Suprabasal keratinocytes: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 39.0;HaCaT: 44.7;Hep G2: 93.8;OE19: 117.1;RT4: 38.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059700 Supported Nucleoplasm Yes NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059700: AB_2684107" "unprognostic (2.04e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.18e-2)" "unprognostic (1.50e-3)" "unprognostic (2.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.68e-4)" "unprognostic (1.49e-2)" "unprognostic (3.16e-3)" "unprognostic (2.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 0.3 0.0 6.9 0.2 5.2 0.0 1.4 7.1 7.1 6.7 3.8 0.8 10.4 0.9 0.3 11.3 3.9 5.4 0.0 4.7 5.1 9.8 6.4 4.0 0.0 5.6 6.0 0.0 6.5 0.1 2.5 1.1 6.0 8.9 0.4 0.1 30.4 1.1 0.2 25.7 0.6 0.0 5.3 0.0 107.2 0.2 7.5 0.6 3.6 0.6 8.0 53.5 16.9 4.7 16.0 1.4 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.1 0.1 39.0 22.6 0.0 0.7 0.0 0.1 44.7 0.0 1.7 0.0 0.0 1.1 0.0 8.2 93.8 0.0 0.0 2.4 0.0 16.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 117.1 0.8 0.0 0.0 0.0 0.4 38.2 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 5.2 7.1 7.1 4.7 5.1 5.6 6.0 6.0 5.3 7.5 4.7 0.3 16.0 10.6 0.0 0.0 60.4 3.2 24.9 6.8 0.0 5.3 5.1 0.8 0.0 16.8 40.5 0.0 0.0 0.0 0.0 1.9 3.0 0.0 5.2 3.0 0.4 0.0 0.0 1.2 13.4 0.0 1.4 67.2 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 2.9 0.0 0.0 0.7 1.8 15.9 0.0 0.0 0.0 0.0 0.5 11.8 0.0 0.0 0.2 0.6 0.0 6.2 5.0 0.0 0.0 0.0 1.6 0.0 0.0 22.2 45.5 0.0 0.3 0.0 0.0 3.9 FRMD7 "FLJ43346, NYS, NYS1" ENSG00000165694 "FERM domain containing 7" Q6ZUT3 X 132076990-132128020 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Neurogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 2.9;kidney: 2.7;smooth muscle: 2.2" "Cell type enriched" "Detected in single" 19 "Distal tubular cells: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.5" "Region enriched" "Detected in many" 28 "olfactory bulb: 65.7" "Region enriched" "Detected in single" 86 "olfactory bulb: 21.3" HPA000886 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" Nucleoplasm "HPA000886: AB_1079269" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (1.64e-2)" "unprognostic (2.28e-1)" "unprognostic (2.18e-2)" "unprognostic (3.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.00e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.0 2.9 0.5 0.0 0.5 0.0 0.1 0.1 0.1 2.7 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.2 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FSCN1 "FLJ38511, p55, SNL" ENSG00000075618 "Fascin actin-bundling protein 1" Q16658 7 5592816-5606655 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 256.5;Hofbauer cells: 274.2;monocytes: 1028.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 600.3;Hep G2: 464.9;K-562: 533.6;NB-4: 600.9;PC-3: 508.2;SH-SY5Y: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000121, HPA005723, CAB035991, HPA050654" Enhanced Supported "Plasma membrane,Cytosol" NA Yes 4300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Plasma membrane" "CAB000121: AB_2278596, CAB035991: , HPA005723: AB_1849159, HPA050654: AB_2681203" "unprognostic (1.91e-1)" "unprognostic (2.03e-2)" "unprognostic (3.12e-2)" "unprognostic (5.00e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (2.28e-4)" "unprognostic (6.31e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.15e-7)" "unprognostic (1.21e-2)" "unprognostic (8.57e-2)" "unprognostic (1.05e-2)" "unprognostic (6.93e-3)" 27.5 39.7 41.5 31.1 62.2 8.3 24.9 26.3 57.2 33.7 10.7 12.1 4.4 19.7 0.7 69.4 15.6 7.6 15.8 39.4 28.2 17.3 8.3 27.6 14.5 49.4 42.7 47.7 5.5 2.3 20.2 27.9 22.8 10.3 1.7 3.4 23.8 2.4 7.3 56.3 12.6 5.7 20.9 55.6 9.3 42.5 79.0 9.0 25.6 2.1 8.3 20.4 41.6 77.1 62.3 139.3 91.2 326.3 34.8 65.4 600.3 144.2 62.4 24.2 26.1 98.5 15.6 1.3 172.0 63.5 24.3 231.3 52.2 229.9 2.1 70.6 28.7 4.8 142.0 464.9 18.0 0.2 13.9 40.8 66.6 46.1 37.2 40.4 118.3 0.7 533.6 0.9 31.6 6.9 2.0 600.9 238.4 4.2 508.2 140.0 22.3 2.3 34.9 5.9 73.1 482.4 121.0 2.6 5.3 58.5 3.9 38.4 246.4 167.4 289.3 99.1 151.0 0.9 0.8 0.7 107.8 0.6 317.2 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 41.5 62.2 26.3 57.2 39.4 28.2 49.4 42.7 22.8 20.9 79.0 77.1 90.0 3.2 4.1 1.6 8.3 181.2 26.7 75.1 189.5 9.4 32.3 44.3 10.4 1.5 13.4 1.8 0.0 6.7 10.8 3.9 0.0 12.8 14.3 8.0 37.8 120.6 42.1 28.0 12.1 5.1 110.8 48.9 10.7 10.1 16.5 256.5 84.6 0.8 274.2 0.0 10.9 5.4 8.2 28.0 136.1 12.3 25.4 27.4 51.6 23.4 1028.2 73.5 0.0 4.5 43.2 15.5 1.1 9.1 4.2 7.5 0.4 0.4 2.9 2.6 0.0 29.7 46.3 5.7 8.0 121.2 147.2 14.6 12.2 8.3 2.6 28.0 FSHB ENSG00000131808 "Follicle stimulating hormone subunit beta" P01225 11 30231014-30235261 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 436 "pituitary gland: 239.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB023410, HPA069703" Enhanced "Secreted to blood" NA NA 78000 "Cluster 26: Pituitary gland - Hormone signaling" "CAB023410: AB_324983, HPA069703: AB_2686176" "unprognostic (1.04e-1)" 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 239.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.7" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 700.1" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 351.1;HaCaT: 292.3;HBEC3-KT: 191.3;HMC-1: 206.5;PC-3: 558.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" 26.1 6.2 0.8 3.0 0.5 0.4 15.2 0.4 0.7 7.7 0.7 9.8 1.8 4.2 3.7 6.5 11.8 7.2 9.4 2.0 2.0 2.9 68.7 8.2 1.6 1.8 1.0 9.9 2.6 0.5 5.9 24.1 0.9 15.5 3.0 0.3 11.3 10.8 9.2 18.0 8.8 4.7 0.5 0.3 11.1 5.0 1.1 2.3 4.0 7.7 12.9 40.4 7.5 0.7 20.0 1.8 33.7 0.0 38.6 13.5 55.4 76.3 351.1 46.4 45.4 0.3 0.2 0.0 0.6 19.9 2.3 292.3 0.0 191.3 32.7 0.8 0.2 4.0 1.7 31.3 20.4 0.3 206.5 31.0 0.5 84.5 55.0 31.3 40.0 0.0 0.0 0.6 29.7 0.1 0.1 1.6 52.1 0.0 558.2 4.2 43.6 0.0 0.0 31.9 0.5 0.1 3.1 0.2 2.0 83.9 0.3 0.3 0.2 124.1 35.3 13.2 11.1 0.4 0.1 0.1 14.8 4.1 116.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.4 0.7 2.0 2.0 1.8 1.0 0.9 0.5 1.1 0.7 5.2 0.0 1.1 0.0 1.0 20.0 31.5 64.4 13.1 0.0 0.9 23.4 11.4 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.4 0.1 3.4 2.9 0.0 0.0 0.1 4.6 14.8 107.7 3.6 0.1 0.0 700.1 1.1 57.2 1.8 0.0 0.7 0.0 2.0 0.8 16.4 1.5 3.1 1.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 11.3 0.2 37.1 0.0 0.1 1.6 0.0 13.1 29.6 33.3 0.3 12.2 4.0 4.7 6.0 2.0 0.3 0.0 51.8 FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 3647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 164.7;hTCEpi: 181.2;SiHa: 341.5;U-2197: 173.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" NA Yes 7000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" 82.9 163.3 16.6 24.1 15.3 13.3 62.4 13.3 19.8 75.6 16.0 82.7 7.7 62.0 6.1 22.0 70.2 16.5 124.1 16.4 17.3 55.9 26.2 132.7 5.5 22.6 16.0 63.8 49.3 3.2 28.9 179.4 17.9 74.9 5.9 2.4 21.1 22.1 11.7 32.3 36.5 42.4 16.7 22.6 43.2 75.2 18.1 2.3 37.9 4.9 1.6 70.5 63.1 18.9 9.5 74.0 5.1 3.7 22.3 56.4 164.7 126.1 18.5 30.7 11.3 27.1 14.4 4.1 49.4 84.7 17.6 65.2 4.1 106.4 10.1 7.8 8.7 3.5 110.2 22.4 95.6 6.7 12.0 70.7 181.2 34.0 140.2 79.3 5.5 3.9 8.2 5.3 46.7 33.1 2.4 4.0 6.2 62.0 26.2 7.2 3.4 8.7 43.1 1.7 3.3 5.7 341.5 6.9 4.3 6.4 6.2 3.5 75.5 30.6 106.6 173.4 46.9 8.5 4.4 2.3 4.7 20.0 14.2 0.0 1.9 0.0 0.4 1.8 0.0 0.1 0.6 0.4 0.9 0.3 1.0 0.6 0.0 0.2 1.4 0.3 0.0 0.9 16.6 15.3 13.3 19.8 16.4 17.3 22.6 16.0 17.9 16.7 18.1 18.9 4.6 19.2 1.9 40.5 1.5 14.5 31.0 11.7 1.8 1.3 11.3 7.9 16.7 32.9 4.4 9.2 0.0 53.9 1.0 1.1 7.9 86.1 8.8 6.4 14.8 8.7 1.2 1.7 9.8 64.3 3647.6 59.6 2.0 18.3 0.0 5.7 16.4 1.9 77.1 3.3 8.4 1.0 0.0 3.7 4.8 7.6 61.2 7.4 5.4 2.8 10.6 6.6 1.0 6.0 5.5 306.5 0.2 26.7 1.0 78.0 1.2 17.7 3.1 1.1 46.0 22.4 57.0 4.6 5.6 4.3 7.7 792.0 2.0 3.6 2.5 30.7 FTH1 "FHC, FTH, FTHL6, PIG15, PLIF" ENSG00000167996 "Ferritin heavy chain 1" P02794 11 61959718-61967634 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Iron storage" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 49889.9;monocytes: 34409.9;Proximal enterocytes: 28837.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 23933.9;HHSteC: 24849.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008623 Approved NA NA 5600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "CAB008623: " "unprognostic (7.15e-2)" "unprognostic (1.52e-2)" "unprognostic (2.27e-1)" "unprognostic (2.00e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (6.18e-4)" "unprognostic (3.08e-2)" "unprognostic (2.48e-2)" "unprognostic (6.65e-2)" "unprognostic (2.44e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (2.99e-1)" "unprognostic (4.89e-2)" "unprognostic (3.44e-1)" "unprognostic (5.83e-2)" 6767.7 5191.4 5741.8 3546.9 5464.0 4734.2 5696.1 5591.9 7973.3 3973.1 4801.2 4701.2 1819.9 3712.8 2421.8 4025.0 3195.6 1995.6 4779.5 5252.8 5737.2 6092.3 3500.8 6057.7 1460.4 6416.7 5812.4 3069.9 3883.8 1696.4 2105.4 1800.3 6188.9 2778.8 3357.4 3123.7 3533.1 1514.8 4695.5 2125.0 4331.6 2040.7 6506.2 3496.3 4044.1 769.5 6153.5 1109.8 3167.6 2766.8 1291.2 4718.0 3163.8 6630.2 3029.8 8290.2 1236.6 3293.8 23933.9 11490.1 6794.4 2684.1 11547.3 2694.6 2698.6 1011.0 4065.8 345.3 16669.6 7830.0 10259.7 5035.8 1118.8 2235.9 1733.9 1439.0 542.9 1720.3 10802.1 6692.1 24849.2 821.6 2626.6 15711.1 10758.7 5384.0 10038.1 8476.6 3427.6 1970.7 2622.1 3874.4 9546.5 4080.7 935.3 1361.8 2114.6 10461.4 13675.6 914.9 1508.5 2502.3 13877.6 8068.8 1044.8 1325.0 9113.3 1005.9 4645.6 4045.3 1790.3 1098.4 3791.5 8310.7 1978.7 3727.4 1732.0 662.7 2516.5 1088.1 11353.7 363.1 2030.4 29466.0 19068.5 15453.6 2306.3 22407.8 2274.9 4088.8 3267.1 2296.9 9762.5 4113.3 2710.5 2108.2 45110.1 1981.1 27515.2 7217.1 4321.5 22214.4 5741.8 5464.0 5591.9 7973.3 5252.8 5737.2 6416.7 5812.4 6188.9 6506.2 6153.5 6630.2 3864.7 1317.3 2890.3 319.3 3200.9 5157.7 7723.2 23426.3 3495.0 881.7 9884.9 10192.4 11.7 4466.7 11711.1 1918.2 573.4 4541.1 4513.5 13653.9 10888.0 10748.7 274.2 4921.8 2908.5 4303.3 2520.6 6318.6 252.8 11073.9 6803.9 5931.3 2059.7 8005.0 6736.0 1798.6 3266.1 5199.9 18411.3 738.6 153.7 3927.4 10379.8 13784.1 49889.9 527.7 4666.1 22792.0 7116.5 183.6 34409.9 12189.1 1699.3 153.3 1031.0 7813.2 7936.8 3818.1 1789.1 12995.8 28837.7 21355.6 5978.6 3311.6 2084.0 2686.9 6139.1 585.4 927.1 1983.6 3555.6 4622.6 5225.4 2496.8 4921.7 18650.3 FTL "MGC71996, NBIA3" ENSG00000087086 "Ferritin light chain" P02792 19 48965309-48966879 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Iron storage" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 14422.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 74983.4;Kupffer cells: 70127.1;Macrophages: 34584.5;Proximal tubular cells: 58047.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 125209.0;monocytes: 102128.9" "Cell line enhanced" "Detected in all" "HHSteC: 24796.9;HSkMC: 20811.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020769, HPA041602" Enhanced Approved Cytosol NA NA 170000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB020769: , HPA041602: AB_2677575" "unprognostic (2.95e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-1)" "unprognostic (1.56e-3)" "unprognostic (7.48e-2)" "unprognostic (5.28e-2)" "unprognostic (2.16e-3)" "unprognostic (6.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" 6778.7 3262.2 6806.2 2353.2 7172.4 4213.8 4226.0 6782.1 10053.2 2094.3 6429.7 2451.1 2427.0 1523.4 1010.8 1306.2 2169.9 4298.0 2537.3 6497.7 6998.4 8845.6 14422.9 7261.1 3353.2 7250.8 6998.4 2455.3 2166.2 931.7 1730.4 3423.2 7218.5 1946.5 1800.0 684.9 1663.5 1390.4 1345.9 1449.7 2806.6 1842.3 7149.5 6751.4 3204.5 455.9 7581.8 1168.9 3000.4 1072.0 1334.6 4239.9 1804.7 7334.0 869.7 12906.5 949.6 1457.0 16013.9 16478.6 1693.1 2194.1 12820.0 3090.7 6903.8 2852.3 3413.2 656.4 4104.3 13203.9 6755.6 505.8 788.2 1301.8 2765.6 8895.0 507.6 1740.0 3222.8 18949.7 24796.9 4133.3 5591.2 20811.1 1735.9 5272.5 2301.6 4590.4 4549.8 774.6 3284.9 1328.2 6198.4 213.0 1152.1 2402.8 1729.8 15140.6 1306.9 947.6 643.0 6763.9 1989.7 545.0 1209.9 701.5 5761.7 313.4 1239.5 5104.1 183.2 8493.4 3438.3 3353.4 1740.1 4364.3 3083.1 5690.2 13742.1 625.1 3563.9 4334.7 6017.7 64938.4 71067.8 77353.0 6560.6 102128.9 7527.7 17097.3 7247.4 7054.3 25176.6 15607.2 8656.4 7466.9 125209.0 4978.3 91398.0 10579.6 9634.4 94147.5 6806.2 7172.4 6782.1 10053.2 6497.7 6998.4 7250.8 6998.4 7218.5 7149.5 7581.8 7334.0 2757.2 1125.0 3379.9 88.5 3311.5 2793.9 6799.5 2785.4 2159.8 474.7 2597.9 3977.3 777.8 4398.0 2550.4 2021.2 177.2 941.5 2199.4 2314.2 10704.0 4251.2 290.2 504.9 1413.1 4867.0 1613.4 4331.2 60.6 6134.8 1447.8 5703.3 1715.1 617.4 2365.7 942.2 4598.0 23702.0 74983.4 533.3 113.8 2368.8 3039.4 70127.1 16939.0 1601.8 4175.9 34584.5 5085.3 129.3 22965.8 3161.9 2020.6 55.8 309.7 6905.5 5604.7 2010.8 4884.7 9790.5 21474.5 58047.8 1908.0 682.6 1341.1 1643.8 3455.6 82.1 311.2 1985.5 2226.7 1502.7 2590.4 1492.0 2816.8 13083.6 FUBP1 "FBP, FUBP" ENSG00000162613 "Far upstream element binding protein 1" Q96AE4 1 77944055-77979110 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006149 Supported Enhanced Nucleoplasm NA NA 300000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA006149: AB_1849172" "unprognostic (4.17e-2)" "unprognostic (2.83e-2)" "unprognostic (3.35e-3)" "unprognostic (3.89e-2)" "unprognostic (3.77e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (9.83e-9)" "unprognostic (2.32e-2)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (3.31e-3)" "unprognostic (9.80e-3)" "unprognostic (9.02e-3)" "unprognostic (1.37e-1)" "unprognostic (1.67e-1)" "unprognostic (6.24e-2)" "unprognostic (9.46e-2)" 29.6 37.8 13.4 35.5 15.3 79.6 30.9 24.0 17.9 28.1 18.5 24.3 24.9 36.4 36.8 24.8 28.5 16.8 29.7 13.8 15.9 39.3 17.1 31.6 42.8 15.6 13.4 46.9 33.7 23.0 41.7 23.0 15.7 24.1 27.5 57.2 30.5 13.3 33.8 27.5 27.5 19.0 15.1 35.2 26.1 17.0 15.3 35.7 36.9 15.2 38.6 25.3 27.4 24.3 49.4 36.5 106.9 40.0 11.9 19.0 77.6 53.5 23.4 35.8 29.2 34.7 49.1 91.3 22.1 31.9 49.1 51.4 54.8 45.4 48.1 91.6 38.5 58.8 87.4 56.9 25.8 104.9 22.8 25.2 35.5 39.7 36.4 39.6 29.2 59.1 65.8 45.1 31.0 39.0 74.0 60.4 75.7 38.0 26.2 94.6 78.7 30.9 35.2 49.0 54.2 61.1 41.5 42.8 44.2 44.7 52.9 38.7 50.7 50.7 66.0 14.7 62.5 44.8 39.4 106.1 21.1 45.3 44.5 6.5 10.5 12.3 20.5 17.0 23.3 19.0 19.6 20.8 9.3 14.7 19.4 23.6 5.3 29.4 19.1 15.4 24.5 15.3 13.4 15.3 24.0 17.9 13.8 15.9 15.6 13.4 15.7 15.1 15.3 24.3 38.6 73.7 57.5 48.0 70.7 84.8 107.0 49.5 39.3 44.7 48.7 31.2 76.4 24.3 71.0 33.1 41.7 46.8 68.2 27.1 43.0 59.5 33.3 54.8 50.7 52.0 55.1 43.1 48.8 72.1 66.2 49.0 28.5 60.5 77.8 59.4 30.4 23.4 33.4 18.5 53.6 35.9 36.7 32.1 37.0 19.8 48.1 41.8 39.2 61.8 61.5 32.5 52.5 56.3 88.3 69.2 33.5 30.1 68.9 54.2 23.6 28.9 73.2 40.5 32.9 70.3 65.7 33.2 41.3 40.9 63.1 35.7 72.1 38.0 37.8 72.7 FUS "ALS6, FUS1, hnRNP-P2, HNRNPP2, TLS" ENSG00000089280 "FUS RNA binding protein" P35637 16 31180138-31191605 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008784, CAB033036, CAB058691" Supported Supported Nucleoplasm NA NA 480000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB033036: AB_2105208, CAB058691: AB_2665583, HPA008784: AB_1849181" "unprognostic (3.06e-2)" "unprognostic (2.53e-1)" "unprognostic (1.86e-2)" "unprognostic (8.68e-2)" "unprognostic (1.44e-1)" "unprognostic (8.03e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (5.22e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-3)" "unprognostic (1.12e-3)" "unprognostic (1.87e-1)" "unprognostic (5.27e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" 88.6 47.6 43.6 102.9 48.6 98.9 65.1 50.6 59.2 85.3 27.2 72.5 59.5 102.0 40.9 58.5 99.2 38.8 70.4 46.9 48.6 83.6 54.3 64.8 97.9 44.3 43.0 134.2 57.3 85.0 47.2 58.3 46.9 59.1 62.8 59.4 60.0 70.4 98.6 53.8 62.6 98.1 45.7 69.3 59.4 69.1 44.8 174.1 58.6 86.0 113.2 87.5 63.2 52.1 386.6 337.2 492.6 292.9 128.3 101.7 429.3 504.1 253.1 319.6 238.3 440.7 254.9 579.6 359.3 310.7 349.4 173.0 563.6 421.0 284.3 341.5 304.7 486.6 224.6 445.3 222.7 529.7 348.5 222.4 99.8 437.5 258.9 120.1 295.7 419.6 537.6 204.7 357.0 483.0 446.2 475.5 649.0 307.7 402.0 677.0 535.9 350.1 344.0 265.6 279.1 478.9 344.5 255.7 267.8 314.9 291.8 597.5 276.3 371.5 365.5 242.1 520.5 181.4 350.4 779.0 204.4 364.2 460.9 12.3 38.2 52.8 53.6 67.3 49.9 29.1 36.5 45.9 41.7 35.2 40.3 43.9 35.0 37.3 59.3 50.3 31.0 27.4 43.6 48.6 50.6 59.2 46.9 48.6 44.3 43.0 46.9 45.7 44.8 52.1 414.6 102.5 121.2 58.1 470.7 144.8 345.7 201.0 507.6 272.6 209.8 223.8 102.1 112.9 156.3 104.8 131.3 299.3 488.8 266.8 68.4 183.6 130.8 201.0 366.1 278.4 212.1 188.2 75.4 154.8 398.5 309.0 222.8 309.7 229.7 445.0 174.2 59.1 208.5 201.9 85.9 229.5 132.2 148.4 270.7 51.2 307.3 282.7 165.4 94.6 185.4 230.8 341.9 117.6 122.2 175.7 219.4 215.5 266.6 245.4 205.4 69.7 115.4 266.3 164.3 584.4 344.2 221.0 237.1 443.6 154.3 295.1 518.2 327.9 232.6 281.2 FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.9;Cholangiocytes: 45.8;Horizontal cells: 141.3;Peritubular cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Cell line enhanced" "Detected in many" "AF22: 24.8;HSkMC: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" 5.4 4.4 2.4 2.7 2.5 1.1 10.7 5.8 2.4 9.9 11.1 5.9 5.1 8.6 4.3 5.2 5.5 5.7 12.7 4.7 2.9 9.6 2.5 10.7 1.3 2.5 6.2 10.1 4.7 2.4 3.9 10.0 2.3 10.3 3.7 2.0 9.0 16.4 1.9 10.4 5.1 5.3 2.3 3.2 4.6 1.6 3.4 1.8 20.5 2.4 1.3 6.4 11.2 2.0 0.8 2.5 24.8 2.6 19.8 17.0 4.5 9.2 5.8 3.3 2.3 1.1 4.3 0.0 2.2 5.9 4.2 4.7 3.9 2.0 2.2 0.0 4.9 0.2 4.6 1.3 1.4 4.2 1.0 32.3 3.6 7.6 2.4 12.6 0.7 2.8 1.5 3.6 9.7 6.2 0.8 1.1 6.4 1.3 4.2 5.1 15.3 0.4 5.3 11.8 3.4 6.5 7.0 5.6 1.6 5.7 3.0 3.8 3.8 13.9 10.4 15.0 3.8 3.3 2.5 0.4 15.0 3.5 16.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.2 2.4 2.5 5.8 2.4 4.7 2.9 2.5 6.2 2.3 2.3 3.4 2.0 5.7 3.2 1.5 4.6 1.1 4.2 44.9 7.0 10.8 1.6 27.7 29.5 18.5 45.8 4.6 12.9 2.1 3.4 0.6 7.4 0.0 4.3 0.3 12.0 13.1 4.5 3.5 0.8 0.6 2.0 2.2 18.5 2.0 15.7 12.7 1.8 15.4 0.9 3.5 141.3 1.0 3.0 4.1 17.4 16.2 1.1 33.2 14.3 17.8 1.9 4.6 3.0 1.0 1.0 0.2 1.9 4.8 45.1 0.4 11.7 6.0 11.6 2.4 2.9 0.0 6.2 10.3 0.5 3.7 9.1 5.1 2.1 0.6 2.6 4.6 7.3 FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Kupffer cells: 9.8;Leydig cells: 23.3;Peritubular cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 53.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: AB_2683497" "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 1.5 1.6 1.0 1.4 1.5 0.2 1.3 0.9 1.2 5.9 10.5 1.8 0.9 5.3 1.3 0.9 3.8 1.8 2.8 1.1 1.3 2.8 0.2 2.9 0.8 1.3 1.9 3.3 1.5 2.1 1.1 3.6 2.0 1.7 0.4 0.7 1.0 1.9 0.4 0.6 1.6 1.5 1.3 2.1 1.2 1.5 1.4 0.3 2.4 0.7 0.7 2.0 2.5 1.6 12.9 37.7 38.3 13.8 8.7 6.4 0.4 39.5 30.4 53.4 38.2 28.4 6.2 0.0 8.9 13.9 13.1 5.5 3.6 2.8 30.2 2.9 7.2 1.7 6.6 0.1 7.7 0.2 7.5 10.7 2.8 9.6 8.8 40.8 1.8 4.9 2.5 0.3 20.9 5.9 6.7 3.6 26.8 0.1 6.7 18.1 8.6 1.9 7.7 0.6 3.8 10.9 5.2 1.1 2.3 32.4 14.6 8.4 0.7 24.1 17.5 4.4 22.6 0.8 0.7 3.0 4.0 2.4 11.3 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.2 1.0 1.5 0.9 1.2 1.1 1.3 1.3 1.9 2.0 1.3 1.4 1.6 0.5 19.2 0.0 1.6 0.6 0.6 0.3 0.9 0.0 0.0 0.9 2.9 1.9 0.0 0.2 1.8 0.0 1.6 1.8 0.0 0.0 0.3 0.6 1.1 8.4 0.7 1.2 1.3 0.0 1.8 0.5 5.9 0.0 1.5 0.0 1.4 0.7 0.0 4.8 0.0 0.0 0.3 0.0 9.8 6.0 0.4 23.3 5.6 0.0 6.5 6.2 6.0 0.0 0.0 0.2 0.7 0.0 18.0 0.3 0.1 0.0 0.3 0.2 0.4 0.0 0.4 5.3 0.3 1.2 0.3 0.4 2.3 0.2 2.4 0.0 0.0 G6PD G6PD1 ENSG00000160211 "Glucose-6-phosphate dehydrogenase" P11413 X 154531391-154547572 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.9" "Cell type enhanced" "Detected in many" "monocytes: 112.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 412.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 412.7" "Cell line enhanced" "Detected in all" "A549: 2333.8;MCF7: 883.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000247, HPA000834" Enhanced Enhanced "Centriolar satellite,Cytosol" No No 2400000 "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Centriolar satellite" "HPA000247: AB_1078978, HPA000834: AB_1078977" "unprognostic (1.73e-2)" "unprognostic (1.53e-3)" "unprognostic (1.13e-2)" "unprognostic (1.02e-1)" "unprognostic (7.78e-2)" "unprognostic (4.34e-2)" "prognostic unfavorable (9.45e-13)" "unprognostic (2.78e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.66e-1)" "unprognostic (2.89e-3)" "unprognostic (2.83e-1)" "unprognostic (1.94e-1)" "unprognostic (1.47e-1)" "unprognostic (7.25e-2)" 40.7 39.1 19.9 30.2 21.8 105.9 31.9 20.5 28.3 20.6 20.0 13.9 13.1 21.6 13.3 54.3 19.3 46.5 14.3 21.3 22.7 12.7 6.5 29.4 28.9 25.4 22.2 24.1 13.0 9.6 27.5 13.7 24.5 12.2 13.1 26.1 21.2 14.4 4.2 21.3 12.4 25.6 19.7 26.9 18.1 54.0 26.1 26.2 45.9 5.1 37.2 33.8 22.4 21.9 168.5 2333.8 49.7 189.7 207.2 281.7 43.5 116.0 341.7 120.0 205.8 111.2 61.9 110.9 174.1 274.3 475.9 146.3 79.3 202.5 60.3 111.4 55.0 116.8 517.2 244.6 401.6 117.8 373.5 136.6 58.5 233.9 49.8 185.6 252.5 79.8 69.6 46.3 218.4 883.9 77.5 93.0 35.3 549.5 172.2 74.9 28.4 120.5 357.1 210.9 49.6 62.0 115.9 444.5 99.9 65.0 67.1 99.4 289.8 73.1 250.0 102.5 181.8 58.2 80.0 189.8 200.6 77.5 150.9 166.1 84.9 412.7 50.3 72.1 32.1 16.0 13.7 36.7 40.1 17.0 16.5 28.2 137.4 69.3 63.5 18.9 18.7 72.8 19.9 21.8 20.5 28.3 21.3 22.7 25.4 22.2 24.5 19.7 26.1 21.9 7.9 0.0 17.0 4.6 21.5 12.5 24.3 46.6 8.6 6.2 14.6 8.6 1.1 14.3 22.9 11.0 18.8 29.6 58.9 25.5 29.4 39.3 10.3 7.7 13.7 13.2 9.5 37.7 2.9 29.3 41.2 19.6 23.4 10.7 37.5 26.1 18.2 1.6 45.6 33.7 2.3 11.5 24.4 58.2 26.0 20.8 26.1 56.6 19.6 5.6 112.3 13.6 83.4 3.5 3.7 31.0 11.4 16.1 21.6 23.9 18.5 18.3 10.9 32.5 6.6 7.5 23.6 10.9 32.8 34.4 13.8 36.3 33.8 11.6 13.5 30.5 GADD45A "DDIT1, GADD45" ENSG00000116717 "Growth arrest and DNA damage inducible alpha" P24522 1 67685201-67688334 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.5" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 858.9;Basal prostatic cells: 2807.1;Glandular and luminal cells: 982.6;Urothelial cells: 1740.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 48.4" "Group enriched" "Detected in all" 5 "granulocytes: 48.4;T-cells: 18.6" "Cell line enhanced" "Detected in all" "HHSteC: 365.9;hTERT-HME1: 577.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053420 Supported "Nuclear speckles" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA053420: AB_2682144" "unprognostic (1.36e-2)" "unprognostic (3.29e-2)" "unprognostic (9.58e-2)" "unprognostic (3.76e-3)" "unprognostic (5.81e-2)" "unprognostic (1.36e-2)" "unprognostic (1.57e-3)" "unprognostic (2.80e-3)" "unprognostic (1.42e-1)" "unprognostic (6.26e-2)" "unprognostic (3.43e-2)" "unprognostic (5.21e-2)" "prognostic favorable (8.06e-6)" "unprognostic (6.11e-2)" "unprognostic (2.89e-1)" "unprognostic (3.43e-3)" "unprognostic (1.93e-1)" 122.0 15.9 21.0 20.0 24.7 136.2 83.7 19.2 27.5 65.6 22.3 29.6 24.8 69.5 23.3 39.2 42.3 44.2 62.2 20.8 24.0 147.2 164.9 75.0 13.7 34.7 26.8 49.6 20.2 19.5 19.1 22.2 24.6 25.6 21.2 19.0 32.4 36.9 240.5 57.9 32.2 38.3 18.6 26.8 53.2 12.3 25.3 30.7 73.8 26.4 16.8 50.4 44.4 28.7 138.6 9.7 22.3 7.5 44.8 43.9 219.8 239.5 122.6 88.5 96.7 50.8 25.3 61.1 71.4 42.0 206.6 85.3 3.0 219.6 164.5 44.9 23.6 75.7 24.0 51.8 365.9 22.5 7.5 76.7 117.8 107.7 577.7 41.5 61.0 15.2 165.6 109.9 104.5 4.8 7.2 27.3 29.8 19.3 96.3 16.4 177.2 67.9 44.2 110.5 102.7 17.1 51.9 15.2 158.3 79.7 2.6 23.2 61.6 85.7 111.6 89.3 165.7 267.3 54.9 106.8 37.8 11.1 86.3 23.6 5.7 48.4 6.3 2.8 5.3 2.3 4.4 5.3 2.6 1.5 1.2 2.0 8.2 6.5 2.0 4.1 18.6 8.7 21.0 24.7 19.2 27.5 20.8 24.0 34.7 26.8 24.6 18.6 25.3 28.7 402.5 64.1 19.0 6.8 51.2 858.9 2807.1 273.2 225.3 45.1 56.7 100.6 190.5 47.1 155.8 103.0 10.4 24.6 85.1 175.3 236.7 264.4 1.6 410.7 250.6 176.6 131.7 116.2 6.1 253.6 117.8 177.0 87.7 982.6 44.5 18.9 74.6 110.1 18.6 26.9 7.0 99.6 122.1 23.5 290.6 4.0 38.2 94.7 158.3 7.5 273.2 30.3 12.3 6.6 1.0 367.3 202.0 64.7 116.8 786.2 101.4 530.0 135.1 72.8 52.6 136.0 201.6 3.7 18.8 365.2 390.8 17.6 139.5 88.6 70.3 1740.4 GADD45G "CR6, DDIT2, GADD45gamma, GRP17" ENSG00000130222 "Growth arrest and DNA damage inducible gamma" O95257 9 89605012-89606555 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 317.8;liver: 366.0" "Cell type enriched" "Detected in many" 7 "Syncytiotrophoblasts: 1609.4" "Cancer enhanced" "Detected in all" "prostate cancer: 79.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 4.9" "Lineage enriched" "Detected in single" 24 "granulocytes: 4.9" "Group enriched" "Detected in many" 4 "HDLM-2: 116.8;SCLC-21H: 58.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023606 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA023606: AB_1849409" "unprognostic (5.84e-2)" "unprognostic (1.61e-2)" "unprognostic (1.08e-2)" "prognostic favorable (7.06e-4)" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.77e-3)" "unprognostic (3.75e-2)" "unprognostic (7.65e-3)" "unprognostic (4.16e-3)" "prognostic favorable (3.80e-5)" "unprognostic (1.11e-1)" "unprognostic (1.63e-2)" "unprognostic (4.95e-1)" "unprognostic (3.88e-2)" "unprognostic (3.41e-1)" "unprognostic (1.22e-1)" 19.6 143.4 12.3 3.8 18.9 14.7 24.6 25.2 19.9 135.0 8.2 26.1 6.0 53.2 1.8 13.1 26.5 2.9 317.8 11.6 16.1 25.4 366.0 26.8 1.6 13.8 13.7 74.3 78.4 28.5 127.5 25.3 12.4 74.4 1.5 3.1 19.7 10.4 139.0 35.8 19.6 7.4 12.1 6.6 44.5 29.9 15.8 2.4 20.7 23.5 0.6 30.6 38.8 13.2 3.1 0.0 16.0 0.0 0.0 0.0 21.1 1.1 0.0 0.1 0.0 2.6 0.3 0.0 2.5 0.0 0.8 2.3 5.3 0.1 0.0 116.8 1.0 0.3 0.3 0.0 0.8 0.0 0.4 0.4 2.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 4.9 0.2 1.1 14.7 2.7 0.2 1.2 4.7 1.2 0.2 0.7 58.6 13.4 1.1 6.3 0.1 3.0 2.5 0.1 2.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 12.3 18.9 25.2 19.9 11.6 16.1 13.8 13.7 12.4 12.1 15.8 13.2 124.2 6.4 53.7 4.6 15.4 28.6 50.9 9.9 40.5 43.9 118.2 215.3 196.8 62.9 22.5 11.0 6.2 80.7 46.6 21.6 92.0 18.3 2.1 40.7 98.3 48.8 54.8 6.6 1.1 43.4 12.1 138.9 97.3 29.3 19.6 24.7 11.0 215.2 57.0 3.3 2.2 55.9 50.8 12.4 121.1 9.0 84.5 77.6 35.6 2.8 11.7 35.7 0.0 0.0 1.1 20.4 11.1 45.5 13.2 88.9 24.9 40.6 23.5 22.0 131.5 90.9 144.4 3.6 2.0 95.5 19.6 1609.4 57.5 165.8 20.0 12.4 GAS1 ENSG00000180447 "Growth arrest specific 1" P54826 9 86944362-86947506 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Growth arrest" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 105.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 127.1;Muller glia cells: 90.3;Skeletal myocytes: 213.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 30.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.2;ASC diff: 29.3;BJ hTERT+: 59.8;HSkMC: 41.1;RH-30: 91.1" "Low region specificity" "Detected in all" "CAB024164, HPA036085, HPA066902" Approved Approved "Nuclear speckles" NA NA 27000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "CAB024164: AB_2107950, HPA036085: AB_2674932, HPA066902: AB_2685746" "unprognostic (2.78e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.97e-2)" "unprognostic (6.15e-2)" "unprognostic (2.84e-2)" "unprognostic (6.46e-2)" "unprognostic (6.91e-2)" "unprognostic (3.32e-1)" "unprognostic (1.28e-3)" "unprognostic (2.25e-3)" "unprognostic (4.30e-2)" "prognostic unfavorable (1.96e-5)" "prognostic unfavorable (8.26e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.13e-5)" "unprognostic (3.59e-2)" 81.5 6.4 3.6 16.6 4.4 0.2 38.3 3.5 4.4 27.1 16.1 27.6 2.2 105.4 15.2 5.8 60.7 10.5 27.1 3.2 2.7 12.5 2.2 7.8 6.8 3.8 3.8 45.1 11.2 1.9 8.4 22.1 3.6 22.6 2.3 3.3 13.1 9.6 12.2 22.2 9.3 43.4 3.4 3.6 16.3 1.8 3.8 7.1 15.9 9.3 3.1 22.5 27.1 6.8 0.0 0.0 7.5 44.2 29.3 10.9 0.8 8.8 59.8 2.9 2.6 0.0 0.1 0.0 0.5 15.8 0.3 0.6 0.0 0.3 1.2 5.2 17.8 0.0 25.0 0.0 14.9 0.1 0.7 41.1 6.3 1.0 5.3 0.0 0.0 0.9 0.0 0.0 12.6 0.0 0.0 0.4 9.5 0.3 0.1 9.6 91.1 0.0 0.4 0.0 1.0 4.0 12.9 0.0 14.1 4.8 0.1 0.2 0.1 13.0 3.6 0.9 3.0 0.0 0.0 0.0 0.4 0.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.4 3.5 4.4 3.2 2.7 3.8 3.8 3.6 3.4 3.8 6.8 15.8 0.0 0.6 2.0 0.4 25.9 7.5 10.9 10.2 8.3 3.9 28.3 5.5 0.0 3.1 14.7 10.4 21.5 7.8 0.1 9.8 0.5 0.1 2.4 36.6 5.6 0.0 0.4 1.2 0.4 3.7 127.1 1.1 2.0 0.0 2.1 22.9 0.3 5.8 5.0 2.6 0.3 0.0 1.0 15.4 0.9 32.3 2.2 17.8 1.9 0.2 90.3 7.2 8.5 4.4 0.2 0.0 12.4 2.1 4.5 0.0 2.6 0.7 3.2 39.5 213.7 15.4 0.3 1.3 1.0 12.5 4.5 2.1 0.8 0.2 0.4 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GAST GAS ENSG00000184502 Gastrin P01350 17 41712331-41715969 "Cancer-related genes, FDA approved drug targets, Predicted secreted proteins" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "stomach 1: 9556.1" "Cell type enriched" "Detected in some" 5 "Glandular and luminal cells: 103.7" "Group enriched" "Detected in many" 6 "pancreatic cancer: 38.8;stomach cancer: 23.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 34.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" CAB000038 Enhanced "Secreted to digestive system" NA NA 87000 "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "CAB000038: " "unprognostic (1.27e-1)" "unprognostic (4.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.75e-2)" "unprognostic (5.68e-2)" "unprognostic (2.11e-1)" "unprognostic (2.85e-1)" "unprognostic (3.17e-1)" "unprognostic (9.07e-2)" 0.0 0.0 0.9 0.0 0.6 0.0 0.7 0.4 0.9 0.2 0.4 0.0 57.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.3 0.0 3.7 0.0 0.8 1.0 0.0 0.0 0.0 0.1 4.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 9.3 9556.1 0.3 2.5 4.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 5.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.8 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.4 0.9 0.5 2.5 0.8 1.0 1.0 0.6 2.5 0.6 0.8 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.3 0.9 0.4 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.1 2.2 13.5 18.7 0.7 0.0 0.0 0.0 0.0 0.1 1.0 0.5 103.7 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.8 0.2 0.2 0.0 0.0 8.8 1.0 0.0 0.0 0.4 GATA1 "ERYF1, GATA-1, GF1, NF-E1, NFE1" ENSG00000102145 "GATA binding protein 1" P15976 X 48786562-48794311 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 59.9" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 165.6" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "eosinophil: 471.7" "Lineage enriched" "Detected in single" 1877 "granulocytes: 471.7" "Group enriched" "Detected in some" 9 "HEL: 221.5;HMC-1: 211.9;K-562: 238.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA000232, HPA000233, CAB009195" Enhanced Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB009195: AB_2232148, HPA000232: AB_1078949, HPA000233: AB_1078951" "unprognostic (1.93e-1)" "unprognostic (7.54e-2)" "unprognostic (8.95e-3)" "unprognostic (3.84e-3)" "unprognostic (2.25e-1)" "unprognostic (3.00e-4)" "unprognostic (4.87e-2)" "unprognostic (3.48e-2)" "unprognostic (4.44e-2)" "unprognostic (1.95e-2)" "unprognostic (6.04e-2)" "unprognostic (7.71e-3)" "unprognostic (4.13e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-1)" "unprognostic (9.10e-2)" "unprognostic (2.71e-2)" 0.2 0.1 0.0 0.1 0.2 59.9 0.1 0.2 0.1 0.2 0.0 0.2 0.5 0.3 0.0 0.2 0.1 0.6 0.1 0.0 0.2 0.2 0.3 2.0 0.1 0.3 0.2 0.0 0.0 0.0 0.2 1.0 0.2 0.3 0.3 0.4 0.1 0.1 0.0 0.3 0.5 0.3 0.2 2.0 0.5 1.4 0.2 0.1 0.1 0.4 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 221.5 0.0 0.0 0.0 0.2 211.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 238.9 0.4 0.0 0.0 0.1 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 83.6 0.2 471.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.2 0.0 0.0 4.4 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 0.2 0.2 0.2 0.6 0.0 0.0 1.3 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 165.6 0.1 0.0 0.5 0.3 0.0 0.0 37.9 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.4 31.5 0.0 9.2 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 1.2 0.2 0.0 0.0 GATA2 NFE1B ENSG00000179348 "GATA binding protein 2" P23769 3 128479427-128493201 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Phagocytosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 261.6;Glandular and luminal cells: 116.5;granulocytes: 638.7;Syncytiotrophoblasts: 321.4" "Group enriched" "Detected in all" 5 "endometrial cancer: 12.7;prostate cancer: 36.7;urothelial cancer: 13.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 330 "basophil: 513.2" "Lineage enriched" "Detected in single" 4344 "granulocytes: 513.2" "Cell line enhanced" "Detected in many" "BEWO: 281.0;HEL: 360.7;HMC-1: 187.4;SH-SY5Y: 325.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005633, CAB024847" Enhanced Supported Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "CAB024847: , HPA005633: AB_1078954" "unprognostic (1.71e-1)" "unprognostic (8.90e-2)" "unprognostic (1.12e-1)" "unprognostic (8.61e-2)" "unprognostic (8.67e-2)" "unprognostic (4.17e-2)" "unprognostic (5.96e-3)" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.12e-2)" "unprognostic (3.58e-2)" "unprognostic (3.04e-1)" "prognostic favorable (2.04e-4)" "unprognostic (2.50e-1)" "unprognostic (8.07e-2)" "unprognostic (2.08e-1)" "prognostic favorable (5.22e-5)" 16.9 9.8 7.1 2.7 5.3 5.1 12.8 3.6 4.6 32.9 2.1 6.6 4.3 42.7 7.1 4.9 49.7 10.7 19.5 3.9 3.4 20.7 1.3 34.8 2.8 8.2 12.2 4.3 13.7 6.9 9.7 22.5 7.9 54.4 2.9 0.1 4.8 52.2 6.4 9.2 8.5 10.8 4.0 11.4 6.6 2.7 8.8 0.8 7.3 5.2 1.2 33.8 23.9 4.1 24.4 5.9 1.3 15.9 2.0 0.6 281.0 53.8 45.2 18.0 6.5 10.0 10.7 0.5 14.8 31.9 1.5 25.5 14.7 0.0 7.6 0.0 8.3 360.7 42.9 16.0 4.0 36.8 187.4 0.3 0.3 0.7 0.3 2.9 28.6 0.2 96.7 0.5 0.4 9.0 0.1 74.2 1.0 0.2 1.8 0.1 7.0 0.4 0.5 21.5 21.8 325.9 13.6 70.1 2.4 14.4 13.5 15.0 52.0 1.2 0.7 12.7 7.4 0.1 0.0 0.2 0.6 2.5 3.7 513.2 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.9 7.1 5.3 3.6 4.6 3.9 3.4 8.2 12.2 7.9 4.0 8.8 4.1 69.0 6.4 27.7 0.0 0.9 4.8 25.5 0.0 1.2 0.2 1.5 1.5 5.7 0.0 1.8 75.4 0.0 63.4 2.3 0.5 1.9 0.2 10.1 74.2 43.2 75.4 3.0 62.4 0.0 14.2 261.6 8.8 0.5 116.5 638.7 0.9 57.5 0.2 10.8 0.0 0.0 0.3 0.0 0.3 4.6 6.4 0.6 7.9 8.8 15.9 0.7 0.1 0.0 0.0 0.0 0.9 0.0 0.4 5.4 29.5 0.0 0.2 0.7 0.2 0.0 2.2 11.0 0.6 4.7 0.9 2.4 321.4 14.0 0.2 0.3 10.5 GATA3 HDR ENSG00000107485 "GATA binding protein 3" P23771 10 8045378-8075198 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 109.9;skin 1: 172.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 267.1;Cytotrophoblasts: 323.5;Extravillous trophoblasts: 746.6;Suprabasal keratinocytes: 198.9;Syncytiotrophoblasts: 1134.9" "Group enriched" "Detected in many" 24 "breast cancer: 190.0;urothelial cancer: 87.0" "Group enriched" "Detected in many" 5 "midbrain: 28.3;pons: 12.6" "Group enriched" "Detected in many" 41 "gdT-cell: 19.9;MAIT T-cell: 26.9;memory CD4 T-cell: 36.7;memory CD8 T-cell: 28.8;naive CD4 T-cell: 19.9;naive CD8 T-cell: 18.3;NK-cell: 36.1;T-reg: 43.6" "Group enriched" "Detected in many" 57 "NK-cells: 36.1;T-cells: 43.6" "Cell line enhanced" "Detected in many" "BEWO: 190.2;MCF7: 473.4;RT4: 194.3;SH-SY5Y: 161.2;T-47d: 605.2" "Region enriched" "Detected in single" 6 "midbrain: 6.1" "Group enriched" "Detected in some" 11 "medulla oblongata: 5.2;midbrain: 14.0;pons: 11.8;thalamus: 13.1" "CAB016217, HPA029730" Enhanced Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB016217: AB_2108591, HPA029730: AB_10601907" "unprognostic (1.70e-1)" "unprognostic (7.23e-2)" "unprognostic (3.58e-2)" "unprognostic (2.00e-1)" "unprognostic (7.03e-3)" "unprognostic (4.68e-3)" "unprognostic (4.23e-2)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (3.83e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (6.31e-2)" "unprognostic (1.82e-3)" 6.7 6.4 0.9 3.8 0.2 4.1 34.2 0.2 0.2 3.4 0.8 0.7 1.0 0.6 8.6 0.6 0.5 1.2 2.5 0.1 0.6 24.9 1.0 3.4 7.8 3.9 28.3 0.1 0.3 109.9 5.0 32.2 12.6 11.2 0.7 0.0 19.9 24.9 2.1 172.9 2.4 0.3 0.5 7.2 1.5 0.2 4.1 25.0 3.0 1.0 3.8 38.8 10.8 0.2 33.8 8.1 0.0 0.4 0.0 0.0 190.2 0.7 0.0 0.0 0.1 12.4 29.9 0.0 0.1 0.0 0.0 28.9 3.2 0.6 0.1 95.8 10.2 0.2 0.3 0.1 2.1 0.1 0.5 0.0 6.9 0.1 1.8 1.0 15.3 45.8 0.4 0.0 0.1 473.4 54.2 0.5 3.5 6.5 4.5 2.8 2.6 0.8 0.0 194.3 9.8 161.2 0.5 26.8 0.0 34.1 605.2 0.1 0.0 2.4 5.9 1.4 4.3 0.9 0.0 0.0 1.3 0.0 1.7 0.1 0.1 0.0 19.9 0.0 26.9 0.4 36.7 28.8 0.0 0.1 19.9 18.3 0.7 36.1 0.0 0.0 43.6 7.0 0.9 0.2 0.2 0.2 0.1 0.6 3.9 28.3 12.6 0.5 4.1 0.2 14.6 0.0 6.0 0.0 3.4 94.8 69.6 1.6 0.0 0.0 267.1 167.3 1.3 0.0 1.5 178.4 0.0 323.5 49.2 0.0 0.0 0.2 0.2 0.5 0.4 12.6 0.0 2.1 0.0 0.4 746.6 5.3 2.6 0.7 2.5 0.0 6.8 0.6 30.7 0.0 0.0 0.0 0.0 3.5 9.9 0.1 0.0 3.8 8.8 1.0 1.5 0.0 51.5 0.0 0.0 4.1 1.1 0.0 12.2 45.8 0.0 0.6 0.3 0.0 0.0 1.1 2.8 0.0 1.4 1.0 198.9 1134.9 93.4 0.5 0.0 106.1 GCLM GLCLR ENSG00000023909 "Glutamate-cysteine ligase modifier subunit" P48507 1 93885199-93909456 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 48.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 207.9;Erythroid cells: 301.9;Prostatic glandular cells: 762.3;Urothelial cells: 374.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009568, HPA023696, CAB040554" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1100000 "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009568: AB_2107835, CAB040554: , HPA023696: AB_1849560" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (8.85e-3)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (4.64e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.37e-1)" "unprognostic (1.07e-1)" "unprognostic (3.53e-1)" "unprognostic (3.51e-2)" "unprognostic (3.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (2.34e-3)" 12.2 13.1 5.4 6.6 4.7 15.0 6.6 5.1 5.4 4.5 5.6 6.2 19.2 3.6 4.0 6.6 14.3 14.1 4.7 4.7 7.5 11.3 48.5 5.9 4.6 6.4 6.9 2.8 7.7 6.7 3.4 10.3 7.1 5.6 5.5 3.6 4.5 5.9 16.0 3.0 12.7 3.6 5.1 6.8 5.7 3.2 5.7 5.0 16.8 11.8 10.1 6.9 3.7 6.1 37.7 58.6 6.4 12.6 20.9 13.0 24.4 43.7 27.3 32.8 24.3 9.9 21.7 14.2 84.8 28.8 106.7 37.3 9.6 18.0 26.2 38.6 12.7 98.9 37.4 42.8 39.1 36.8 15.2 16.1 6.7 67.0 10.7 13.2 36.4 16.0 40.0 20.5 24.0 7.3 26.8 8.5 21.5 36.0 27.4 12.3 19.0 20.9 23.6 43.4 14.8 6.1 41.3 32.2 15.4 71.8 7.2 22.7 38.4 34.1 20.1 64.5 66.7 18.1 25.0 14.7 28.2 20.4 12.2 2.1 0.3 0.7 2.6 0.2 1.5 1.3 2.5 3.4 0.3 2.0 1.5 1.6 1.5 2.3 0.3 1.0 0.7 0.7 5.4 4.7 5.1 5.4 4.7 7.5 6.4 6.9 7.1 5.1 5.7 6.1 28.7 41.7 19.1 16.0 14.6 11.5 207.9 33.2 24.5 24.8 24.2 34.2 16.4 61.5 29.0 29.5 6.2 63.5 39.3 21.7 25.4 25.1 3.9 66.3 27.6 55.5 52.5 301.9 32.0 12.3 19.6 44.5 15.8 50.1 19.7 17.3 31.4 102.4 19.9 33.7 30.7 19.9 22.4 20.7 51.4 4.0 21.5 32.0 8.8 15.0 9.3 21.2 34.0 11.1 11.6 24.2 8.0 12.4 21.6 762.3 47.2 65.1 64.3 13.1 0.0 48.4 37.1 32.0 36.7 33.5 9.2 45.0 34.1 26.5 17.8 374.9 GDF15 "MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB" ENSG00000130513 "Growth differentiation factor 15" Q99988 19 18374731-18389176 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 371.8;urinary bladder: 175.4" "Cell type enhanced" "Detected in many" "Club cells: 1160.8;Syncytiotrophoblasts: 4304.7;Urothelial cells: 3294.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Group enriched" "Detected in many" 5 "granulocytes: 2.7;monocytes: 1.2" "Cell line enhanced" "Detected in many" "BEWO: 416.5;Hep G2: 225.5;HHSteC: 564.9;TIME: 213.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011191, CAB062554, HPA070957" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 1260000 960000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "CAB062554: AB_2665632, HPA011191: AB_1078962, HPA070957: AB_2732168" "unprognostic (1.04e-1)" "unprognostic (1.89e-2)" "unprognostic (3.45e-2)" "unprognostic (3.36e-2)" "unprognostic (2.04e-2)" "unprognostic (2.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.30e-2)" "unprognostic (2.80e-1)" "unprognostic (2.89e-1)" "unprognostic (5.09e-2)" "unprognostic (1.46e-1)" "unprognostic (6.55e-3)" "unprognostic (3.81e-2)" "unprognostic (8.45e-2)" "unprognostic (1.25e-1)" "unprognostic (3.04e-3)" 34.8 11.7 1.3 1.5 1.4 0.4 24.9 1.0 2.3 18.9 40.9 29.2 4.5 13.6 2.2 4.8 5.5 19.9 4.5 4.3 1.3 371.8 88.6 46.9 0.6 2.0 1.7 4.7 112.3 25.9 12.3 86.9 1.5 105.3 24.4 1.2 12.5 4.6 5.5 6.4 12.3 1.9 1.2 11.4 75.5 1.6 2.5 0.3 11.2 0.5 1.7 175.4 19.2 1.6 1.8 95.6 9.4 3.5 22.3 18.5 416.5 33.1 17.9 1.2 18.8 4.2 29.6 0.4 58.8 3.0 97.0 0.7 0.0 12.2 4.7 0.2 2.2 0.9 9.2 225.5 564.9 0.1 35.7 48.8 140.1 90.7 58.6 0.7 99.5 0.0 152.4 0.7 22.9 23.5 0.1 0.8 5.4 34.4 52.5 0.2 3.7 0.2 69.9 94.6 0.9 1.0 0.4 5.5 127.9 35.1 2.6 0.4 213.1 0.0 7.4 1.8 1.5 1.5 4.0 0.4 51.9 0.1 27.8 0.0 0.7 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.7 0.0 1.2 0.0 0.0 0.1 1.3 1.4 1.0 2.3 4.3 1.3 2.0 1.7 1.5 1.2 2.5 1.6 6.6 35.3 62.4 0.0 1.8 1.3 350.6 366.1 0.0 0.1 54.2 15.5 0.7 47.1 1160.8 259.3 0.0 60.6 0.4 176.0 33.2 316.9 0.0 166.8 35.4 31.9 84.8 0.0 0.1 381.9 263.4 52.9 224.8 261.8 29.2 0.2 2.5 7.0 33.8 0.0 0.1 357.6 453.7 1.6 3.7 0.0 0.9 14.1 3.6 0.0 9.9 0.5 1.0 0.0 0.0 440.4 146.6 1.5 1.3 780.2 22.9 85.7 681.4 0.6 0.0 9.5 46.7 0.7 0.5 1.3 1.7 4304.7 5.5 3.4 291.0 3294.2 GDNF "ATF1, ATF2, HFB1-GDNF" ENSG00000168621 "Glial cell derived neurotrophic factor" P39905 5 37812677-37840041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes, Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8.2;skeletal muscle: 10.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 3.3;Skeletal myocytes: 11.5;Spermatogonia: 3.4;Theca cells: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 41.4;SuSa: 12.6;U-87 MG: 12.6;WM-115: 46.5" "Region enhanced" "Detected in single" "basal ganglia: 2.8" "Low region specificity" "Detected in some" "CAB005210, HPA070283" Supported Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Vesicles Nucleoplasm "CAB005210: AB_2247684, HPA070283: AB_2686246" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (3.54e-2)" "unprognostic (8.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (5.33e-2)" "unprognostic (1.92e-1)" "unprognostic (3.71e-2)" "unprognostic (2.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.10e-1)" "unprognostic (1.16e-4)" "unprognostic (2.04e-1)" "unprognostic (8.86e-2)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" 0.1 0.4 2.3 1.6 1.5 0.1 0.3 5.8 1.4 0.8 0.0 8.2 1.4 1.3 2.5 0.9 0.9 0.9 0.8 0.6 1.6 0.9 0.7 0.0 0.1 0.7 3.1 3.6 0.0 0.0 0.1 5.0 1.0 1.3 2.4 0.3 0.2 4.5 10.1 1.3 2.0 2.1 0.2 0.4 1.6 0.4 6.1 0.1 0.1 4.3 0.0 0.7 0.8 2.9 0.0 0.0 0.1 0.1 1.8 1.0 0.0 5.5 3.4 1.1 1.6 0.0 0.1 0.1 0.0 7.4 0.1 0.2 0.0 0.1 2.2 0.0 0.2 0.0 0.4 0.5 0.2 0.1 0.1 1.8 0.1 41.4 0.0 1.4 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.1 0.4 0.1 0.0 0.1 9.0 0.0 0.0 0.2 0.5 0.0 0.3 0.2 2.7 12.6 0.1 0.0 0.0 5.5 0.0 1.4 6.2 4.0 0.0 0.0 12.6 0.0 46.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 1.5 5.8 1.4 0.6 1.6 0.7 3.1 1.0 0.2 6.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.6 0.6 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 1.5 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.7 0.1 0.0 0.0 11.5 1.8 0.9 3.4 0.0 0.3 0.1 0.0 2.6 0.0 0.5 GH1 "GH, GH-N, GHN, hGH-N" ENSG00000259384 "Growth hormone 1" P01241 17 63917200-63918839 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 868 "pituitary gland: 59365.3" "Cell type enhanced" "Detected in single" "Adipocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043715 Supported "Secreted to blood" NA NA 2690000 6400000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 57: B-cells - Immune response" "HPA043715: AB_2678632" "unprognostic (1.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-1)" "unprognostic (9.45e-4)" "unprognostic (2.48e-1)" "unprognostic (2.09e-4)" "unprognostic (2.03e-2)" "unprognostic (6.57e-2)" "unprognostic (2.33e-1)" 14.8 68.3 0.1 0.0 0.1 0.1 2.1 0.1 0.6 1.9 0.1 3.7 0.5 4.1 0.0 9.5 2.8 0.0 7.8 0.1 0.4 4.1 18.4 3.5 0.0 0.1 0.1 6.1 7.7 0.0 59365.3 0.8 0.1 5.5 0.0 0.0 4.8 0.0 3.5 36.2 3.9 0.0 0.1 7.7 11.8 7.2 0.1 0.3 5.4 0.1 0.0 1.5 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.0 GH2 "GH-V, GHL, GHV, hGH-V" ENSG00000136487 "Growth hormone 2" P01242 17 63880215-63881944 "Cancer-related genes, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 79 "pituitary gland: 102.4;placenta: 127.5" "Group enriched" "Detected in some" 23 "Extravillous trophoblasts: 8.6;Syncytiotrophoblasts: 23.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "BEWO: 8.4" HPA043715 Supported "Secreted to blood" NA NA 4200000 "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA043715: AB_2678632" "unprognostic (1.02e-1)" 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 102.4 127.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 23.7 0.0 0.0 0.0 0.0 GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435595-121449727 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Cataract, Disease variant, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Astrocytes: 276.2;Basal keratinocytes: 234.9;Cardiomyocytes: 199.7;Endometrial stromal cells: 215.5;Granulosa cells: 494.3;Suprabasal keratinocytes: 378.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 462.7;HUVEC TERT2: 362.3;NTERA-2: 365.8;SuSa: 453.4;U-87 MG: 350.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Supported "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: AB_476857, HPA035097: AB_2674460, HPA047551: AB_2732540, HPA069245: " "unprognostic (3.37e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-1)" "unprognostic (4.18e-2)" "unprognostic (1.48e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (3.00e-3)" 121.2 287.6 313.5 24.7 310.2 0.9 60.6 260.1 409.0 261.7 193.1 17.5 18.2 98.7 10.6 74.9 32.7 99.9 168.9 273.6 362.6 21.2 10.6 67.9 21.1 340.3 380.9 43.5 19.4 236.2 31.3 290.2 307.4 83.3 19.7 3.3 35.6 148.0 10.3 388.2 24.7 112.5 335.9 4.2 30.7 36.9 373.3 24.3 169.1 22.1 34.9 116.0 184.9 341.0 0.1 43.5 186.8 0.4 99.7 61.5 0.4 142.5 286.9 46.9 113.7 0.7 0.4 0.0 15.8 55.8 40.2 18.3 5.1 87.4 151.3 0.1 51.6 2.3 15.7 0.0 124.1 0.0 0.4 164.6 92.1 172.5 61.7 462.7 362.3 0.0 0.1 4.3 9.4 8.4 0.1 80.6 365.8 0.1 47.2 0.1 0.0 3.7 188.6 21.0 0.4 2.9 0.0 0.3 0.1 453.4 14.9 0.3 269.5 143.8 39.4 122.8 93.5 0.1 0.1 0.1 350.4 0.1 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.5 310.2 260.1 409.0 273.6 362.6 340.3 380.9 307.4 335.9 373.3 341.0 152.2 250.0 80.0 276.2 0.1 234.9 133.6 71.1 77.4 0.3 9.5 20.1 199.7 0.0 17.5 1.8 2.1 53.4 0.4 0.0 0.0 76.9 0.5 21.5 215.5 166.6 0.0 0.0 0.3 4.2 7.9 124.4 0.5 51.7 8.8 494.3 33.9 0.1 8.6 0.0 0.6 0.0 4.1 0.9 55.3 1.7 2.5 3.6 44.4 15.0 0.6 0.3 0.0 4.0 1.0 10.8 0.0 4.1 0.1 29.7 0.0 0.1 6.2 0.3 0.0 5.9 80.2 0.9 1.8 68.3 378.2 20.0 4.9 127.1 0.4 52.7 GJB5 CX31.1 ENSG00000189280 "Gap junction protein beta 5" O95377 1 34755047-34758512 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "esophagus: 101.0;skin 1: 95.1;vagina: 35.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 48.6;Basal prostatic cells: 38.0;Basal respiratory cells: 49.6;Squamous epithelial cells: 63.8;Suprabasal keratinocytes: 83.5;Urothelial cells: 66.2" "Cancer enhanced" "Detected in many" "cervical cancer: 36.7;head and neck cancer: 57.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 29.1;HaCaT: 90.8;HBEC3-KT: 40.7;hTCEpi: 147.4;RT4: 50.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038146 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038146: AB_10697242" "unprognostic (2.62e-1)" "unprognostic (1.63e-1)" "unprognostic (3.48e-1)" "unprognostic (5.71e-2)" "unprognostic (8.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.89e-2)" "unprognostic (2.76e-2)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.30e-2)" "unprognostic (1.09e-3)" "unprognostic (2.36e-1)" "unprognostic (2.41e-3)" "unprognostic (5.59e-2)" "unprognostic (5.67e-3)" 0.2 0.1 1.0 0.0 1.0 0.0 3.9 0.6 1.3 12.8 0.0 0.1 0.0 0.1 3.4 101.0 0.6 3.4 0.1 1.4 0.3 0.1 0.4 0.3 0.0 0.4 0.4 0.1 1.1 0.0 0.8 0.6 0.5 5.2 0.1 0.0 13.9 3.1 0.3 95.1 0.2 0.0 0.6 0.1 0.1 2.3 0.7 1.4 0.9 0.1 12.6 7.1 35.0 0.9 29.1 0.3 0.1 0.5 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 2.2 0.0 1.2 0.0 0.3 90.8 0.0 40.7 0.0 0.1 0.0 7.0 0.9 0.0 0.0 0.0 0.0 0.1 147.4 0.0 23.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 50.9 0.1 0.0 3.6 1.5 0.0 0.4 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.6 1.3 1.4 0.3 0.4 0.4 0.5 0.6 0.7 0.9 0.0 0.0 1.1 0.3 0.0 48.6 38.0 49.6 12.5 0.0 2.8 1.9 0.5 0.0 17.2 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 4.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.5 0.0 0.0 12.4 0.0 0.0 0.0 1.4 0.0 0.0 63.8 83.5 0.4 0.2 0.0 0.3 66.2 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703145 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 2571.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 1500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: AB_2684126" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 55.4 62.3 69.4 38.9 74.1 31.6 74.2 74.6 83.4 55.9 77.2 51.8 116.3 57.8 110.9 60.0 72.3 41.4 88.9 72.6 76.2 87.2 157.7 66.6 48.4 73.7 72.8 82.8 42.1 106.1 23.2 64.1 75.1 171.4 52.3 100.3 43.2 62.1 154.2 66.6 67.7 61.8 77.9 48.2 48.5 27.9 72.9 50.0 54.8 128.8 60.3 52.4 51.6 77.1 201.6 92.0 257.4 256.7 119.2 213.9 227.0 171.1 161.4 235.4 243.0 224.4 75.3 222.5 132.2 137.5 280.1 129.5 222.5 221.1 295.8 203.8 343.0 329.4 105.7 211.3 178.5 126.7 2571.5 183.9 133.5 223.7 159.0 153.2 258.5 154.9 264.7 143.6 223.3 170.6 199.5 160.5 185.5 179.2 176.7 171.0 311.1 145.8 217.8 149.9 199.3 201.3 120.6 165.4 329.8 175.9 192.4 628.3 107.6 182.0 167.1 159.8 275.9 112.7 227.0 608.6 66.1 322.7 299.6 23.7 20.7 15.3 35.5 33.4 48.0 51.9 35.3 36.7 39.0 51.4 32.7 34.9 2.7 23.5 26.9 60.4 34.1 33.3 69.4 74.1 74.6 83.4 72.6 76.2 73.7 72.8 75.1 77.9 72.9 77.1 69.2 131.4 174.4 26.1 86.3 64.6 112.6 88.2 37.0 56.1 67.7 55.8 133.2 58.6 84.5 90.1 20.9 102.7 68.3 34.1 248.4 132.1 4.5 76.2 58.8 74.3 36.5 83.5 23.9 73.3 323.0 86.0 53.0 67.5 71.4 78.7 161.0 114.0 78.8 69.0 21.9 39.3 99.7 125.7 72.8 6.5 83.9 70.0 104.9 17.8 92.6 190.3 49.4 25.1 24.8 77.3 36.0 109.9 86.4 178.8 103.2 132.2 80.7 65.5 46.0 62.0 70.9 15.0 16.1 77.2 88.2 73.2 62.4 123.7 63.4 130.2 GMNN Gem ENSG00000112312 "Geminin DNA replication inhibitor" O75496 6 24774931-24786099 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "DNA replication inhibitor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 231.4" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 184.8;Paneth cells: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011458, CAB047327, CAB047328, HPA049977, HPA054597" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 25: Pancreas - Digestion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB011458: AB_2110946, CAB047327: , CAB047328: , HPA049977: AB_2680978, HPA054597: AB_2682538" "unprognostic (1.37e-1)" "unprognostic (3.43e-3)" "unprognostic (3.91e-3)" "unprognostic (1.52e-2)" "unprognostic (1.28e-1)" "unprognostic (4.37e-2)" "unprognostic (2.90e-3)" "unprognostic (8.29e-2)" "unprognostic (1.23e-3)" "prognostic favorable (4.13e-4)" "prognostic unfavorable (9.77e-4)" "unprognostic (1.33e-2)" "prognostic unfavorable (7.82e-5)" "unprognostic (2.25e-1)" "unprognostic (7.92e-2)" "unprognostic (3.63e-2)" "unprognostic (5.90e-3)" 10.1 7.7 16.9 17.2 18.2 68.9 24.2 19.5 23.7 11.1 13.5 41.6 17.8 10.6 5.8 16.6 16.5 7.9 8.0 14.7 20.2 24.6 18.2 8.9 30.4 17.0 20.2 14.6 231.4 8.4 11.1 16.5 17.8 41.5 44.4 16.3 8.7 24.9 7.4 40.3 16.1 12.5 16.4 19.1 22.6 37.4 19.8 37.4 10.8 14.3 23.7 28.4 13.9 15.5 110.9 64.2 159.2 66.2 22.2 23.5 106.0 106.0 55.9 124.4 135.5 125.1 38.8 110.1 131.3 34.4 91.3 63.3 139.4 78.1 133.0 41.2 145.4 151.5 109.3 207.4 20.7 119.1 53.1 19.1 25.1 75.9 29.5 25.8 62.2 84.6 193.9 56.9 88.9 86.3 224.9 128.2 87.3 89.6 50.2 128.9 124.4 141.2 53.5 94.6 127.3 78.3 47.5 77.4 95.2 89.1 81.3 72.0 30.9 75.7 76.8 88.3 182.6 62.8 207.6 210.3 23.1 220.9 111.2 5.5 5.2 17.1 4.4 6.9 5.6 9.2 8.5 6.9 7.6 4.6 6.1 6.9 3.0 5.9 5.0 9.4 15.9 5.6 16.9 18.2 19.5 23.7 14.7 20.2 17.0 20.2 17.8 16.4 19.8 15.5 24.0 6.4 15.6 8.8 17.0 33.0 28.4 57.4 18.8 9.5 51.0 52.5 12.1 18.6 68.1 44.1 2.1 83.2 19.9 72.6 9.8 113.6 94.8 84.8 30.6 18.4 25.9 66.2 3.5 112.3 136.3 17.7 12.2 184.8 13.3 36.4 13.9 17.4 54.0 11.8 5.3 66.3 10.2 10.7 13.2 28.0 9.6 15.2 23.2 5.6 12.6 30.9 6.2 5.5 3.2 31.8 300.5 10.9 41.6 25.6 20.8 20.6 25.2 13.7 19.7 8.0 21.9 158.8 58.8 26.8 63.5 48.7 19.1 30.4 156.5 30.1 GNA11 "FBH, FBH2, FHH2, HHC2" ENSG00000088256 "G protein subunit alpha 11" P29992 19 3094362-3123999 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 330.6;Proximal enterocytes: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA048886: AB_2680544" "unprognostic (4.64e-3)" "unprognostic (2.21e-1)" "unprognostic (3.12e-1)" "unprognostic (2.23e-2)" "unprognostic (1.30e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.56e-2)" "unprognostic (1.40e-1)" "unprognostic (6.26e-2)" "unprognostic (7.85e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.48e-11)" "unprognostic (1.05e-2)" "unprognostic (1.01e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" 33.5 32.5 36.4 16.2 31.2 8.3 32.6 53.8 35.3 31.7 18.9 66.7 117.5 42.4 12.7 28.7 44.5 20.0 51.7 33.5 27.3 40.4 26.2 34.7 7.5 30.3 29.6 32.5 33.9 26.3 29.8 22.3 28.6 40.4 38.7 11.0 33.3 47.1 54.2 34.4 139.3 28.7 26.6 21.4 34.9 50.6 31.3 8.5 32.9 39.2 7.0 38.8 27.0 31.1 56.1 31.2 27.9 48.5 41.7 28.4 30.9 53.8 53.7 71.8 57.8 41.7 27.3 12.0 29.2 76.4 43.6 39.0 37.8 42.7 44.3 30.1 21.9 3.3 35.7 23.6 42.2 3.8 11.8 36.9 36.8 48.4 29.2 36.9 57.8 3.4 27.8 1.9 49.1 25.8 3.0 14.4 20.5 38.4 29.4 23.2 26.4 11.9 33.8 40.8 66.0 40.7 38.3 45.2 27.2 18.9 33.3 7.9 50.0 45.7 33.3 85.4 73.5 1.3 3.9 7.9 33.0 2.9 52.3 2.5 1.4 0.3 0.7 0.7 0.8 0.9 0.5 0.6 0.2 1.1 1.2 0.9 5.1 0.5 1.5 2.3 0.1 0.3 36.4 31.2 53.8 35.3 33.5 27.3 30.3 29.6 28.6 26.6 31.3 31.1 62.3 32.1 24.1 5.2 3.5 32.6 9.5 15.4 13.6 22.7 43.2 47.9 17.8 35.8 12.6 27.6 37.5 13.2 2.4 330.6 7.9 21.4 45.2 26.9 23.0 33.9 54.6 5.2 8.8 25.4 13.5 25.3 29.6 26.1 4.5 24.1 58.2 28.5 9.0 45.4 11.3 84.1 26.4 9.1 16.4 20.0 50.1 5.1 23.2 11.2 1.1 29.0 0.0 7.1 14.1 36.1 96.0 80.5 1.2 16.0 323.0 18.9 35.4 15.8 19.7 28.5 30.5 23.7 8.9 20.6 41.2 20.4 2.0 22.1 94.9 13.4 GNA13 "G13, MGC46138" ENSG00000120063 "G protein subunit alpha 13" Q14344 17 65009289-65056740 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 144.5" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 537.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010087 Approved Supported Cytosol NA NA 320000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA010087: AB_10601478" "unprognostic (2.55e-1)" "unprognostic (2.27e-1)" "unprognostic (1.33e-3)" "unprognostic (1.23e-3)" "unprognostic (8.21e-2)" "unprognostic (7.05e-2)" "unprognostic (4.22e-3)" "unprognostic (1.09e-1)" "unprognostic (7.77e-2)" "unprognostic (4.66e-1)" "unprognostic (1.16e-2)" "unprognostic (1.94e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.59e-1)" 23.7 22.5 21.3 41.5 23.9 144.5 15.8 25.0 22.5 17.6 21.3 27.7 21.0 17.9 10.5 18.2 15.9 26.5 12.6 20.2 26.6 17.6 27.0 27.1 46.8 26.9 21.7 22.6 15.3 15.8 8.3 39.3 30.1 15.1 26.2 17.2 10.4 16.1 36.8 12.1 23.3 22.9 25.4 33.5 18.0 15.4 23.7 49.9 17.9 38.6 44.6 30.5 12.3 35.2 33.3 36.9 32.6 21.6 31.8 29.5 32.2 25.3 28.7 35.0 39.7 20.7 23.0 130.0 16.1 26.6 42.0 22.5 35.0 29.4 51.5 35.4 19.5 69.0 20.7 38.7 45.7 54.2 45.5 23.9 43.8 32.2 42.0 29.1 48.6 33.6 29.7 82.3 36.9 29.3 88.9 18.8 19.4 30.2 25.7 49.0 64.8 47.2 32.0 53.3 24.5 48.8 19.7 34.8 43.8 62.1 40.7 50.0 37.9 58.4 48.8 25.0 33.2 57.3 79.4 151.4 20.1 32.2 30.4 7.3 6.0 7.6 5.6 12.5 5.7 4.5 6.8 6.8 5.2 4.0 3.9 4.4 13.8 6.8 8.5 2.1 9.7 4.0 21.3 23.9 25.0 22.5 20.2 26.6 26.9 21.7 30.1 25.4 23.7 35.2 34.5 12.8 13.0 68.9 80.9 67.8 27.8 13.1 42.1 5.3 21.0 13.0 11.7 18.6 10.1 9.2 4.2 16.6 60.5 82.2 7.9 11.8 4.5 25.3 23.6 35.4 16.8 21.2 20.7 11.6 15.1 24.3 23.9 49.9 30.4 21.9 32.5 13.8 57.4 6.7 27.3 11.6 12.2 57.9 537.6 8.0 11.5 123.8 69.4 44.0 44.1 34.4 29.9 29.1 36.7 13.4 30.7 24.0 45.9 28.3 23.5 16.4 13.8 6.1 32.9 19.2 19.9 6.7 13.6 33.7 65.9 14.0 66.5 15.4 13.7 36.2 GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 79768028-80226181 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 220.0;Oligodendrocytes: 410.7;Suprabasal keratinocytes: 214.2;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "NK-cell: 12.8" "Lineage enriched" "Detected in many" 6 "NK-cells: 12.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022449, HPA042141" Approved Supported Nucleoplasm,Nucleoli,Centrosome NA NA 1600000 "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "Nucleoplasm, Nucleoli" "CAB022449: , HPA042141: AB_2677870" "unprognostic (2.29e-1)" "unprognostic (2.83e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.92e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (9.78e-2)" "unprognostic (1.26e-1)" "unprognostic (4.48e-1)" "unprognostic (9.41e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.12e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" 47.5 26.2 8.9 2.6 18.8 0.4 34.9 14.9 17.7 18.5 4.4 25.4 4.7 14.8 0.7 19.7 10.9 3.2 9.4 10.8 13.3 36.6 15.2 15.2 2.0 18.8 15.0 17.1 4.5 1.3 10.9 13.6 18.4 8.8 2.6 1.5 10.4 3.0 6.2 47.9 9.9 4.1 15.5 5.9 17.7 13.0 14.2 1.3 14.2 2.9 1.5 24.7 19.9 36.6 2.2 18.6 10.5 0.0 14.5 7.9 9.1 14.3 7.2 5.5 8.7 0.0 3.4 0.0 4.5 9.3 5.1 2.6 7.0 9.5 5.4 0.0 11.9 10.4 12.9 1.2 14.8 1.8 0.0 12.0 19.9 4.1 9.5 4.4 3.5 0.0 0.0 0.1 7.7 0.6 0.0 0.1 6.1 0.2 11.0 8.6 5.2 7.8 15.7 7.0 12.5 9.2 13.5 0.0 10.3 5.4 2.0 0.3 13.0 21.8 15.6 5.1 4.4 0.0 0.0 0.2 6.1 1.2 10.2 1.3 0.4 0.4 0.1 0.4 0.0 0.0 0.1 0.1 1.9 0.1 1.1 0.5 0.3 12.8 1.0 0.2 0.1 0.4 8.9 18.8 14.9 17.7 10.8 13.3 18.8 15.0 18.4 15.5 14.2 36.6 121.1 19.2 13.8 11.4 0.9 220.0 20.6 81.6 35.3 3.9 7.0 7.7 6.7 21.5 42.3 29.5 0.0 83.6 1.3 11.1 88.0 7.2 1.7 23.2 58.5 31.5 19.9 4.2 71.4 3.8 84.6 35.9 4.6 40.3 30.3 43.9 17.5 20.0 10.0 26.9 77.4 7.8 36.7 1.0 28.6 7.0 33.5 3.9 103.2 4.7 2.9 49.1 0.0 53.3 410.7 9.4 6.3 74.4 1.2 17.4 0.9 18.4 36.8 5.0 111.7 10.6 70.8 9.7 45.7 31.9 214.2 183.5 2.9 2.9 10.7 19.2 GNAQ "G-ALPHA-q, GAQ" ENSG00000156052 "G protein subunit alpha q" P50148 9 77716097-78031811 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 556.6;Excitatory neurons: 405.6;Microglial cells: 394.4;Oligodendrocyte precursor cells: 338.3;Oligodendrocytes: 495.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 27.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 27.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010036, HPA048886" Uncertain Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA 800000 "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB010036: AB_631536, HPA048886: AB_2680544" "unprognostic (2.10e-1)" "unprognostic (8.53e-2)" "unprognostic (1.45e-1)" "unprognostic (4.37e-2)" "unprognostic (1.87e-1)" "unprognostic (6.83e-3)" "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.11e-7)" "unprognostic (1.90e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" 23.5 21.3 37.2 18.8 42.2 43.8 20.1 35.8 51.3 21.1 19.3 30.3 14.5 23.7 18.7 23.2 16.9 20.1 8.6 51.0 38.5 20.9 22.0 31.1 9.9 40.5 42.7 22.4 14.6 16.3 12.5 21.7 39.9 21.2 27.2 10.4 16.8 25.7 10.5 8.9 16.8 27.4 42.4 11.3 27.9 11.5 45.5 19.7 23.1 11.8 9.1 23.5 13.8 48.5 30.6 34.1 29.8 32.0 34.9 35.5 42.8 40.7 29.7 16.6 20.6 10.5 24.1 0.1 32.0 35.5 24.5 48.5 22.5 23.4 20.6 1.1 12.5 83.0 29.0 21.4 31.4 51.8 30.0 24.3 28.0 33.9 32.5 34.3 42.7 70.3 14.8 0.2 29.5 38.5 58.8 31.0 24.0 46.5 4.7 22.0 36.5 0.3 37.8 64.5 33.1 49.6 29.3 23.3 30.5 27.5 22.2 18.3 55.0 29.2 1.9 41.9 24.0 0.2 0.1 0.3 20.3 28.9 32.0 27.0 2.5 5.7 0.8 2.2 1.7 0.9 2.0 1.1 2.8 0.9 2.1 1.7 8.9 3.6 4.5 3.2 2.2 1.5 37.2 42.2 35.8 51.3 51.0 38.5 40.5 42.7 39.9 42.4 45.5 48.5 117.7 176.3 97.5 556.6 4.8 47.3 38.4 42.7 39.3 34.0 75.6 54.5 6.0 58.6 48.3 77.3 16.7 47.4 33.4 137.0 7.9 36.2 18.9 57.5 64.2 107.3 92.3 58.0 405.6 39.7 53.2 51.7 70.8 76.0 50.7 40.2 98.6 64.0 53.7 82.4 242.0 92.5 30.5 139.5 173.9 11.1 39.4 128.8 48.0 394.4 114.6 40.5 8.2 338.3 495.2 54.2 60.7 52.3 6.2 70.5 52.9 45.4 67.0 5.0 26.3 62.3 40.8 5.6 13.2 46.3 21.6 29.0 25.0 45.2 75.4 70.1 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GNB1 ENSG00000078369 "G protein subunit beta 1" P62873 1 1785285-1891117 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "retina: 2629.0" "Cell type enriched" "Detected in all" 5 "Rod photoreceptor cells: 1373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040736 Supported Approved "Golgi apparatus,Plasma membrane" NA NA 1900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus" "HPA040736: AB_2677106" "unprognostic (9.49e-2)" "unprognostic (4.91e-3)" "unprognostic (1.24e-1)" "unprognostic (1.56e-1)" "unprognostic (3.34e-1)" "unprognostic (9.07e-3)" "prognostic unfavorable (3.61e-6)" "unprognostic (1.99e-2)" "unprognostic (3.60e-1)" "unprognostic (7.27e-2)" "unprognostic (8.47e-3)" "unprognostic (1.95e-1)" "unprognostic (9.76e-2)" "unprognostic (1.08e-1)" "unprognostic (4.62e-2)" "unprognostic (1.14e-1)" "unprognostic (7.90e-2)" 178.1 123.8 167.9 179.9 212.3 147.6 119.7 147.8 234.4 124.3 87.1 165.7 173.7 127.1 90.8 126.7 114.4 110.9 119.6 228.3 172.0 125.1 103.3 146.7 160.0 159.5 153.2 130.2 105.9 148.2 106.8 141.1 169.5 118.3 123.1 2629.0 120.6 118.9 66.8 111.8 208.2 156.1 131.6 142.6 129.7 99.0 168.9 167.3 113.6 97.1 145.6 152.6 102.7 203.9 373.2 344.2 400.2 280.4 222.4 242.4 154.4 515.4 339.9 456.2 355.2 282.8 361.8 385.5 369.3 522.5 258.6 192.0 405.5 373.5 411.4 595.9 199.2 375.0 308.2 325.6 279.1 227.7 394.4 216.4 256.6 437.2 402.9 306.1 376.8 298.8 236.8 337.8 440.0 230.3 501.9 177.4 230.8 190.0 275.0 482.9 308.7 306.4 310.8 227.5 489.9 556.5 477.1 306.6 420.5 272.8 214.8 305.9 579.4 399.3 267.5 314.8 379.1 227.1 432.8 888.7 341.4 470.1 230.5 11.4 13.3 21.9 9.9 16.4 9.1 9.0 9.9 11.2 13.3 9.6 6.7 7.2 22.1 12.8 17.5 22.7 12.5 8.2 167.9 212.3 147.8 234.4 228.3 172.0 159.5 153.2 169.5 131.6 168.9 203.9 172.0 70.5 42.6 57.5 67.9 86.3 51.6 47.4 33.0 149.8 65.3 57.8 60.6 52.9 42.4 75.4 175.2 44.2 124.4 140.9 46.9 88.0 29.1 93.3 112.9 131.6 122.9 40.3 102.4 100.5 99.4 77.8 52.0 121.6 53.8 101.9 95.3 60.3 100.8 180.0 101.9 95.5 40.7 152.7 114.6 33.8 76.1 128.0 53.4 115.2 119.5 250.3 73.2 70.9 110.1 175.4 91.0 88.0 75.3 100.5 167.6 67.4 41.1 1373.7 78.9 71.0 105.9 68.8 67.1 51.6 101.7 36.4 74.5 83.7 83.0 94.1 GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase subunits alpha and beta" Q3T906 12 101745499-101830959 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 192.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" NA NA 160000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "HPA014558: AB_2732409, HPA042343: " "unprognostic (6.72e-2)" "unprognostic (1.66e-1)" "unprognostic (8.71e-3)" "prognostic favorable (8.48e-4)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (2.73e-1)" "unprognostic (8.57e-2)" "unprognostic (3.73e-2)" "unprognostic (1.09e-2)" "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (6.86e-2)" "unprognostic (3.44e-1)" "unprognostic (1.02e-1)" "unprognostic (5.44e-2)" "unprognostic (4.98e-2)" 11.9 7.9 18.8 16.2 22.2 23.9 16.4 14.4 20.0 17.4 2.7 29.6 14.2 11.8 6.2 15.6 8.8 14.8 21.5 22.7 10.8 14.5 9.4 27.0 20.6 8.5 11.1 7.2 11.3 23.0 8.4 14.8 9.7 20.1 30.3 13.0 54.3 13.0 16.4 25.1 16.2 15.9 8.9 19.0 21.3 10.4 12.4 34.1 13.9 25.9 17.8 19.3 12.0 13.3 18.2 17.5 6.4 10.9 52.3 24.8 19.6 25.4 52.3 24.7 32.2 13.5 12.4 38.1 17.9 35.1 20.1 23.2 29.8 32.8 38.4 18.1 15.6 16.3 15.4 19.3 9.7 15.0 31.7 19.3 17.7 23.5 13.8 61.4 44.0 30.0 25.9 11.0 23.4 27.8 45.6 21.0 22.0 22.6 12.5 10.6 32.6 51.2 39.5 46.8 13.6 11.2 42.3 29.7 60.7 23.5 30.6 9.8 43.6 23.1 12.5 19.6 14.4 30.0 32.9 21.5 26.4 21.8 14.6 8.6 3.8 4.4 18.8 3.6 6.2 3.0 4.0 10.3 7.1 4.9 5.1 7.9 1.4 17.0 4.6 6.9 3.3 3.7 18.8 22.2 14.4 20.0 22.7 10.8 8.5 11.1 9.7 8.9 12.4 13.3 25.3 60.9 65.0 35.9 42.1 16.8 32.9 16.2 17.1 23.6 25.2 18.9 43.5 18.6 27.8 22.0 25.0 25.7 107.3 68.3 7.9 10.3 0.6 25.3 23.7 21.1 18.0 19.5 84.5 15.1 15.0 18.9 33.1 61.6 122.8 24.6 10.4 9.7 46.7 8.4 83.8 29.6 24.4 46.7 17.6 3.8 17.1 41.2 42.7 30.0 43.5 26.9 192.6 135.2 19.8 15.7 129.3 12.8 63.9 28.1 17.7 13.8 10.0 37.0 0.0 18.6 14.9 12.4 33.0 26.7 14.3 8.8 63.4 30.6 49.7 46.5 GOLGA5 "golgin-84, GOLIM5, ret-II, rfg5" ENSG00000066455 "Golgin A5" Q8TBA6 14 92794305-92839947 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000992, HPA063876" Enhanced Supported Supported "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA000992: AB_1079009, HPA063876: AB_2685140" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (2.77e-2)" "unprognostic (1.68e-1)" "unprognostic (3.15e-1)" "unprognostic (1.78e-1)" "unprognostic (5.02e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (7.67e-2)" "unprognostic (6.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.06e-2)" "unprognostic (2.49e-2)" 26.0 23.3 21.4 18.2 23.7 10.4 33.1 22.4 26.4 32.2 23.9 26.4 23.3 21.9 54.2 25.0 19.2 24.0 21.5 20.8 22.3 25.5 54.3 22.4 18.8 22.6 22.4 20.6 32.2 33.6 23.5 28.2 23.1 31.2 32.5 15.8 32.4 25.8 26.9 23.3 22.9 26.0 22.6 19.1 32.9 34.3 22.1 16.9 33.2 20.0 23.3 24.1 19.6 25.9 32.4 29.4 25.9 23.7 53.1 71.4 44.3 43.9 80.4 41.9 49.2 21.8 43.4 21.0 35.1 70.2 29.2 33.4 23.1 35.9 56.6 25.8 11.2 19.9 14.0 29.3 61.5 23.3 31.8 55.1 63.7 29.5 60.6 46.2 42.0 21.8 17.7 27.3 46.5 60.1 18.1 19.6 16.1 70.2 31.0 13.9 37.9 21.1 42.8 38.9 18.4 26.0 40.0 29.6 45.7 35.7 51.0 25.6 35.0 23.9 15.6 31.3 22.2 33.3 27.6 18.2 54.9 18.2 40.8 10.4 10.0 23.6 10.3 13.0 11.8 9.5 10.4 10.6 9.9 9.5 9.2 8.1 8.8 8.7 11.9 9.1 12.9 6.7 21.4 23.7 22.4 26.4 20.8 22.3 22.6 22.4 23.1 22.6 22.1 25.9 18.7 28.9 26.3 8.8 15.7 7.8 11.2 17.9 16.5 7.5 16.2 11.9 26.8 8.6 19.6 14.7 12.5 23.7 17.2 23.8 29.4 25.3 31.6 17.6 24.6 16.7 22.3 15.8 17.6 32.7 32.0 21.7 33.1 25.7 9.5 29.7 13.9 33.5 15.4 25.2 15.6 31.6 4.1 14.7 10.3 18.5 23.0 14.6 12.4 15.0 18.2 15.6 16.5 14.6 21.9 28.9 12.0 25.2 29.2 19.4 19.9 24.2 18.7 10.7 26.3 18.0 19.3 34.1 37.0 16.5 11.4 50.3 15.9 15.6 16.5 16.5 GOPC "CAL, dJ94G16.2, FIG, GOPC1, PIST" ENSG00000047932 "Golgi associated PDZ and coiled-coil motif containing" Q9HD26 6 117560269-117602542 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019477, HPA024018" Approved Enhanced "Golgi apparatus" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA019477: AB_1849890, HPA024018: AB_1849891" "unprognostic (2.48e-2)" "unprognostic (1.63e-3)" "unprognostic (1.71e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (3.17e-2)" "unprognostic (3.12e-2)" "unprognostic (9.21e-2)" "unprognostic (6.22e-2)" "unprognostic (6.77e-2)" "unprognostic (8.23e-2)" "unprognostic (9.46e-2)" "unprognostic (1.40e-2)" "unprognostic (2.67e-2)" "unprognostic (1.38e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-2)" 15.5 14.2 14.6 15.8 14.9 7.1 20.2 15.6 18.0 23.4 11.0 18.7 12.2 23.5 18.0 12.1 17.4 16.3 22.1 15.9 13.3 14.5 16.4 13.6 19.9 12.5 12.5 25.6 12.7 22.1 16.1 19.9 13.1 16.2 20.3 13.5 14.3 17.3 15.8 18.7 15.0 18.4 13.6 16.9 14.9 17.7 12.6 21.0 23.9 17.4 17.2 15.1 14.7 16.8 14.1 15.0 19.1 25.6 40.1 47.9 30.3 57.1 41.7 30.6 31.5 23.1 15.5 42.2 24.3 32.4 60.4 31.2 37.2 27.6 42.8 21.2 20.8 38.7 39.9 37.5 42.4 52.2 24.8 57.4 74.9 22.8 65.7 60.6 26.5 29.0 36.7 16.8 62.2 12.9 21.8 40.3 16.5 24.0 16.0 33.0 37.0 30.8 23.3 12.9 26.7 21.0 57.6 19.7 15.8 36.3 14.3 49.7 31.8 2.2 27.9 28.5 62.6 29.9 28.8 35.4 37.9 43.4 23.9 10.5 4.2 3.2 6.7 3.9 9.3 7.9 7.1 7.1 5.5 7.7 8.2 8.5 2.9 9.2 4.7 9.2 7.7 4.1 14.6 14.9 15.6 18.0 15.9 13.3 12.5 12.5 13.1 13.6 12.6 16.8 43.2 22.4 22.7 46.4 33.4 46.7 25.1 63.9 46.7 59.2 47.0 67.3 46.2 34.3 32.2 20.2 22.9 77.0 28.6 40.4 27.4 27.9 35.1 30.4 77.4 38.1 33.6 26.5 52.9 25.6 62.4 48.3 30.1 30.6 31.1 50.4 35.0 38.7 38.5 74.0 46.2 65.2 24.4 24.2 22.9 13.7 42.3 27.0 28.4 32.8 24.1 39.3 35.0 73.9 64.5 21.1 40.9 42.2 38.7 40.3 20.9 27.1 35.3 35.9 32.9 50.0 44.3 115.6 51.4 36.7 59.8 52.3 38.7 43.3 37.7 27.3 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 511.1;liver: 369.5;skeletal muscle: 489.9;tongue: 1011.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 449.0;Distal tubular cells: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol NA Yes 100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favorable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favorable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 14.7 54.9 67.8 14.7 71.1 8.0 22.7 70.3 119.1 53.1 82.6 50.9 62.0 13.1 25.9 42.7 17.9 49.0 511.1 70.0 77.6 143.1 369.5 15.5 14.1 83.5 55.0 18.1 34.0 142.4 22.5 14.4 83.7 22.7 59.2 106.2 48.6 27.4 489.9 23.9 45.8 21.4 48.4 16.9 58.9 33.6 69.1 17.7 47.7 1011.6 30.3 22.3 21.0 70.1 73.7 40.3 46.0 114.4 35.1 30.7 127.1 58.9 108.7 101.8 109.8 89.9 56.4 71.9 20.4 50.2 89.2 88.6 107.1 78.9 105.8 25.7 46.7 28.1 46.7 114.3 184.9 77.9 44.0 47.3 82.5 86.9 228.4 69.5 49.5 48.6 71.1 106.2 65.4 64.9 42.5 56.5 29.2 118.7 56.1 45.5 44.4 72.8 173.7 37.5 19.6 28.7 44.8 59.3 222.6 66.8 115.7 27.1 23.3 25.4 56.3 28.0 68.7 76.8 99.7 74.3 65.4 40.8 34.1 4.0 8.7 6.8 19.7 25.8 18.4 17.6 21.5 20.7 21.9 21.2 15.6 22.7 0.8 20.5 31.5 36.4 27.6 15.6 67.8 71.1 70.3 119.1 70.0 77.6 83.5 55.0 83.7 48.4 69.1 70.1 10.3 16.0 16.2 26.1 38.8 11.9 41.8 82.7 24.5 95.6 18.8 21.2 449.0 72.9 34.4 73.5 62.6 35.9 10.7 62.1 240.7 51.9 166.7 17.8 9.3 16.7 19.7 39.5 47.4 30.8 18.1 23.5 76.9 21.5 31.8 20.2 17.2 191.8 31.6 75.7 63.3 45.3 54.9 12.4 6.9 24.1 11.1 13.0 49.8 13.1 10.5 36.6 6.2 21.1 37.2 27.6 34.4 14.3 22.4 13.1 97.0 163.3 27.9 76.5 13.1 15.2 20.5 116.7 10.4 40.9 10.4 55.1 14.6 47.0 66.4 42.3 GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734342 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 698.4;tongue: 726.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 341.9;Hepatocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018139, HPA058537" Enhanced "Intracellular and membrane" NA NA 2800000 "Cluster 13: T-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA018139: AB_1849903, HPA058537: " "unprognostic (1.50e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-3)" "unprognostic (2.63e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (1.61e-4)" "prognostic favorable (5.75e-5)" "unprognostic (1.12e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (2.27e-1)" "unprognostic (3.00e-1)" "prognostic favorable (2.90e-9)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (2.22e-1)" 19.6 73.9 52.4 27.4 55.9 21.1 36.3 62.5 66.9 34.1 129.4 57.6 37.4 36.5 66.3 66.9 46.7 24.1 313.2 57.9 59.3 88.0 321.4 25.2 35.6 60.6 51.0 29.4 33.2 98.6 46.7 24.7 62.5 59.0 65.0 91.4 47.7 65.7 698.4 41.1 35.7 46.7 50.1 28.5 54.9 28.9 58.7 35.9 42.6 726.8 57.0 57.0 45.1 61.0 137.2 182.4 93.8 114.8 66.6 59.8 122.0 101.4 108.8 197.6 107.7 158.9 120.1 302.3 117.3 114.6 86.5 195.5 203.2 199.2 250.1 83.1 182.0 81.4 92.1 179.3 84.2 132.3 71.9 58.4 110.9 125.2 108.2 112.4 201.8 141.9 167.0 30.6 102.2 122.5 164.0 128.0 127.7 90.8 338.0 177.8 142.7 291.1 187.9 197.7 148.2 107.6 195.2 208.5 74.8 84.2 105.5 42.7 82.3 71.4 129.3 56.2 132.4 69.9 68.6 247.4 76.7 130.9 73.8 4.6 20.6 7.4 28.3 16.9 43.7 26.5 33.1 34.1 34.7 22.3 30.1 28.4 1.8 30.2 18.4 30.0 48.7 31.2 52.4 55.9 62.5 66.9 57.9 59.3 60.6 51.0 62.5 50.1 58.7 61.0 15.1 9.6 15.8 11.8 19.8 32.0 37.0 39.4 34.1 34.5 27.5 16.3 341.9 22.8 22.5 36.8 77.2 42.6 11.8 42.6 56.7 50.8 4.0 30.4 20.0 23.8 20.5 39.3 24.7 42.5 38.8 21.1 30.1 25.4 14.5 37.5 23.2 176.1 39.1 20.2 27.1 33.5 26.4 17.0 15.1 8.1 18.0 13.5 24.9 5.6 12.7 16.1 8.2 11.6 17.6 40.3 13.3 22.6 39.2 38.2 27.6 63.2 17.5 48.9 0.0 15.2 24.0 11.9 15.0 68.9 30.0 23.7 17.4 36.4 54.4 69.6 GPA33 A33 ENSG00000143167 "Glycoprotein A33" Q99795 1 167052836-167166479 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 215.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 775.5;Intestinal goblet cells: 211.6;Paneth cells: 420.3;Proximal enterocytes: 266.1;Undifferentiated cells: 147.2" "Cancer enriched" "Detected in many" 6 "colorectal cancer: 84.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 24.2;T-reg: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 24.2" "Cell line enriched" "Detected in some" 8 "OE19: 14.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018858, CAB025943" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB025943: , HPA018858: AB_1849909" "unprognostic (2.41e-2)" "unprognostic (1.71e-3)" "unprognostic (1.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (8.39e-4)" "unprognostic (1.55e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-2)" "unprognostic (9.63e-2)" "unprognostic (2.10e-2)" "unprognostic (9.44e-2)" "unprognostic (6.75e-2)" "unprognostic (5.22e-3)" "unprognostic (3.13e-1)" "unprognostic (9.68e-3)" "unprognostic (2.96e-3)" 0.4 0.0 0.0 18.5 0.0 0.7 0.2 0.0 0.2 0.0 0.4 215.9 150.0 0.3 0.0 0.1 0.0 0.2 0.7 0.1 0.1 0.1 0.0 7.1 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 196.2 0.0 0.0 0.4 0.3 0.0 136.9 7.2 0.0 0.9 1.5 0.2 0.2 2.3 0.0 0.1 1.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.3 1.8 14.4 0.0 0.0 0.8 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.8 3.8 1.6 0.2 10.9 5.7 2.7 2.2 24.2 3.5 0.2 0.2 2.6 0.0 19.5 6.8 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.3 775.5 0.0 0.0 3.9 0.0 0.0 0.1 26.1 0.8 0.4 0.0 0.0 0.0 0.5 0.0 4.5 0.0 0.0 0.0 0.5 0.0 0.3 211.6 0.0 1.9 1.3 2.3 0.3 1.8 0.0 0.0 0.3 0.4 0.0 0.0 0.1 0.1 420.3 0.0 0.0 0.0 266.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.1 0.0 3.1 0.0 147.2 0.2 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in some" 5 "HAP1: 514.3;Hep G2: 1825.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 99.9 22.8 0.5 3.5 1.0 0.0 61.8 0.5 0.3 11.8 0.2 6.5 1.6 9.2 41.1 6.7 13.9 13.7 24.5 0.3 4.0 87.0 5.1 122.9 2.5 1.9 3.1 15.5 21.2 4.1 47.0 574.9 3.0 8.3 4.1 6.2 13.7 9.2 4.5 18.0 5.6 7.3 1.7 3.7 13.6 2.8 2.0 8.0 22.4 28.6 10.9 14.6 9.3 1.0 0.0 0.0 21.8 1.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 154.0 0.0 0.0 0.1 0.1 0.0 0.0 514.3 0.4 0.0 0.0 22.6 0.0 0.9 1825.2 0.3 0.0 0.5 12.9 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.5 0.1 132.1 0.1 0.0 0.0 0.0 0.1 122.4 6.1 15.3 40.3 0.0 0.0 0.4 233.8 0.5 23.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 1.2 0.0 0.7 0.0 0.0 0.0 0.1 0.5 1.0 0.5 0.3 0.3 4.0 1.9 3.1 3.0 1.7 2.0 1.0 28.5 0.0 1.7 0.3 1.0 10.5 4.8 17.0 0.0 0.4 5.0 10.4 0.5 1.5 20.0 5.5 0.0 65.1 0.8 0.5 19.6 0.3 0.9 0.2 0.4 1.8 1.8 0.0 2.5 1.6 61.0 404.2 0.5 1.5 0.0 1.0 2.2 0.0 26.7 0.0 2.5 3.1 2.0 0.0 6.1 2.4 10.5 1.0 3.6 23.4 0.0 88.9 0.0 3.5 1.4 1.7 2.6 3.0 0.4 2.7 1.2 40.7 24.3 3.1 0.0 21.7 21.3 6.9 7.1 0.2 4.0 148.6 1.1 7.6 4.1 0.6 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.4" "Group enriched" "Detected in many" 4 "Astrocytes: 493.0;Excitatory neurons: 686.5;Inhibitory neurons: 866.7;Oligodendrocyte precursor cells: 576.1;Oligodendrocytes: 597.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Approved Vesicles,Cytosol NA NA 6900 "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favorable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (4.61e-5)" 13.8 11.1 35.5 3.5 36.0 2.6 13.4 48.4 54.1 9.7 20.9 11.8 7.4 9.9 11.6 12.2 11.1 6.2 17.1 36.1 37.6 25.3 62.4 9.3 3.8 32.7 35.3 8.9 23.9 11.7 13.6 3.6 32.3 11.3 10.1 23.1 9.4 6.6 24.5 15.2 9.0 6.2 32.4 6.7 14.7 6.2 34.6 5.8 11.9 13.8 4.3 11.4 10.7 39.5 39.9 8.8 13.7 15.9 14.2 17.5 9.5 11.1 5.7 12.7 12.2 2.8 17.9 0.0 1.8 7.7 5.5 13.1 17.0 19.9 18.9 15.0 14.9 15.8 9.4 22.3 7.8 9.1 15.8 13.3 13.8 2.9 16.0 4.8 11.8 13.8 9.3 14.2 7.1 19.2 11.9 22.2 5.0 28.3 17.0 0.0 32.5 13.2 16.7 7.5 25.8 10.3 10.2 31.6 12.4 3.3 18.5 11.5 6.7 14.1 24.8 11.3 13.0 22.8 9.1 0.3 10.5 0.8 11.2 0.0 0.7 0.3 2.0 1.2 3.2 1.2 2.5 1.7 1.1 1.9 1.7 1.6 0.0 1.3 1.0 1.5 3.0 0.7 35.5 36.0 48.4 54.1 36.1 37.6 32.7 35.3 32.3 32.4 34.6 39.5 11.5 6.4 13.1 493.0 11.8 4.7 9.2 5.8 27.9 34.3 12.4 6.7 12.7 8.6 10.8 1.8 52.1 3.9 3.5 8.6 13.7 4.0 3.8 7.2 13.5 10.7 6.0 7.6 686.5 5.3 2.3 8.7 19.9 13.6 0.0 3.9 15.7 47.6 3.7 43.7 866.7 15.0 8.2 5.8 1.7 5.0 11.1 4.5 1.8 148.0 1.3 8.9 1.0 576.1 597.5 3.1 7.8 5.7 15.1 11.5 7.1 20.1 2.4 34.9 0.0 12.5 11.8 11.8 8.9 26.7 5.8 2.1 7.9 9.0 10.4 6.5 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPS2 ENSG00000132522 "G protein pathway suppressor 2" Q13227 17 7311324-7315564 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 279.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067540 Approved Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA067540: AB_2685860" "unprognostic (1.53e-2)" "unprognostic (3.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.71e-3)" "unprognostic (1.55e-1)" "unprognostic (1.53e-4)" "unprognostic (1.37e-2)" "unprognostic (1.33e-1)" "unprognostic (3.18e-2)" "unprognostic (2.84e-1)" "prognostic favorable (7.50e-5)" "unprognostic (1.37e-2)" "prognostic unfavorable (3.42e-5)" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (6.87e-2)" "unprognostic (1.28e-3)" 45.4 47.7 30.3 15.5 30.9 26.8 39.7 30.7 37.8 42.1 28.4 47.5 14.6 39.5 14.2 38.0 36.8 13.2 65.8 30.3 30.9 49.8 33.3 34.0 17.2 31.8 30.7 39.5 39.0 24.4 33.8 13.9 31.1 35.3 17.1 12.0 39.4 16.9 154.9 52.0 34.5 15.6 29.5 34.6 40.0 102.7 31.2 21.6 34.6 52.9 20.1 43.9 37.2 31.7 28.1 60.6 24.9 26.4 36.5 20.2 21.2 20.1 26.7 45.2 39.0 39.2 16.1 32.0 15.5 31.1 32.3 42.1 25.4 42.4 31.5 37.9 34.8 30.1 62.2 53.0 26.4 19.1 37.1 19.3 31.2 59.0 17.1 19.5 26.0 29.7 18.8 8.6 43.2 25.8 38.2 21.2 24.6 29.3 22.8 29.5 30.8 34.1 36.4 32.1 23.5 39.5 35.6 23.6 28.9 21.4 23.6 18.6 15.9 23.0 20.5 28.2 48.9 25.0 37.0 21.0 30.3 23.2 38.1 78.3 47.2 82.7 53.5 59.8 49.5 81.6 56.6 58.5 39.5 63.8 51.9 47.8 79.1 41.5 67.7 66.0 81.2 58.1 30.3 30.9 30.7 37.8 30.3 30.9 31.8 30.7 31.1 29.5 31.2 31.7 29.1 12.8 10.8 19.9 36.9 15.8 11.5 11.4 29.0 29.9 19.2 17.8 1.2 17.2 16.6 20.2 66.7 13.5 55.7 52.4 25.4 21.7 100.3 15.0 22.6 18.9 16.8 29.9 15.0 26.8 11.1 14.9 25.5 17.5 19.0 23.4 11.4 10.6 10.3 38.7 12.5 23.2 6.1 14.1 25.0 279.3 21.1 21.1 19.6 13.1 21.6 15.5 41.2 10.6 17.1 19.5 35.9 15.4 42.2 8.4 42.2 25.7 14.6 44.8 19.7 17.4 18.8 37.4 42.9 18.1 16.9 19.6 39.0 17.1 21.8 9.1 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GPX2 GSHPX-GI ENSG00000176153 "Glutathione peroxidase 2" P18283 14 64939152-64942905 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 497.7;intestine: 453.8;liver: 634.0;stomach 1: 374.6;urinary bladder: 350.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 386.1;Distal enterocytes: 436.6;Gastric mucus-secreting cells: 912.3;Hepatocytes: 753.4;Intestinal goblet cells: 438.6;Paneth cells: 463.0;Undifferentiated cells: 776.8;Urothelial cells: 1062.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 493.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 4748.8" "Region enhanced" "Detected in single" "pons and medulla: 1.2" "Low region specificity" "Detected in some" HPA003545 Enhanced Approved Nucleoplasm,Cytosol NA NA 82000 "Cluster 48: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA003545: AB_10962695" "unprognostic (3.54e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-3)" "unprognostic (4.75e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.96e-2)" "unprognostic (2.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (4.39e-2)" "unprognostic (3.39e-2)" "unprognostic (6.66e-4)" "unprognostic (1.73e-2)" 1.9 0.2 0.1 53.8 0.3 0.3 5.3 0.5 0.3 23.5 0.1 333.5 96.7 0.7 1.7 187.7 4.9 497.7 0.3 0.2 0.5 30.6 634.0 2.6 0.1 0.4 0.2 0.2 24.5 0.0 1.2 0.2 0.4 43.3 453.8 0.0 71.8 24.9 0.3 25.4 175.7 9.7 0.1 0.6 374.6 2.5 0.3 3.3 0.5 0.0 1.2 350.5 108.2 0.7 0.0 1152.6 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 36.9 9.6 0.0 6.0 0.0 1.9 303.7 0.6 4.8 0.0 0.2 0.1 0.1 1.1 1048.6 0.0 0.1 0.4 0.0 9.7 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 5.6 0.6 0.3 1.3 4748.8 0.2 0.5 0.2 0.2 0.1 727.5 324.2 0.2 0.1 13.4 0.0 0.6 0.5 0.0 0.0 0.0 0.8 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.5 0.3 0.2 0.5 0.4 0.2 0.4 0.1 0.3 0.7 0.1 0.0 0.0 0.3 6.9 9.9 169.4 104.5 42.1 0.2 0.6 4.1 0.4 386.1 17.1 23.9 0.0 0.1 0.0 436.6 11.7 272.8 13.8 3.8 0.5 3.5 115.2 50.8 0.2 260.6 0.1 2.1 912.3 2.8 13.4 0.1 17.5 753.4 0.0 0.0 0.2 438.6 36.7 26.1 0.8 66.6 0.9 3.5 0.0 1.9 3.2 0.0 0.0 0.0 0.4 163.7 463.0 0.0 2.4 100.7 68.1 31.4 9.0 0.7 0.0 0.0 3.6 0.4 0.0 315.5 9.7 0.0 5.9 0.1 776.8 1062.0 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 GRB2 NCKAP2 ENSG00000177885 "Growth factor receptor bound protein 2" P62993 17 75318076-75405709 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 340.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002589, HPA030749, HPA030750" Approved Supported Nucleoplasm,Nucleoli NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Nucleoli "CAB002589: AB_10693935, HPA030749: AB_2673590, HPA030750: AB_2673591" "unprognostic (4.83e-3)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (3.42e-3)" "unprognostic (1.70e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.04e-7)" "unprognostic (1.01e-2)" "unprognostic (2.73e-1)" "unprognostic (1.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-2)" "unprognostic (1.08e-2)" "unprognostic (8.13e-2)" "unprognostic (3.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.58e-1)" 55.7 58.0 66.1 98.3 64.8 127.1 40.3 56.6 66.1 35.9 49.9 54.7 57.3 46.4 31.5 51.0 39.5 43.2 53.3 71.0 68.7 50.5 54.0 65.5 116.9 64.1 64.8 39.3 35.0 39.8 42.6 64.5 61.5 41.8 52.6 24.1 40.6 45.8 48.8 36.3 60.6 58.9 67.5 92.2 44.6 18.5 68.5 83.1 37.6 39.1 107.3 67.5 36.1 72.3 98.6 87.7 58.9 71.1 64.1 54.5 129.5 91.2 70.5 89.3 87.3 75.8 66.7 128.9 57.9 97.0 77.5 58.5 84.0 76.1 89.8 63.4 76.5 137.2 55.7 111.8 57.3 162.8 259.0 55.2 78.0 112.9 55.8 62.3 128.3 125.3 95.5 88.8 64.9 127.4 160.3 160.5 40.5 98.9 81.3 113.7 123.8 94.9 82.7 75.0 66.6 101.1 83.7 85.4 114.7 102.8 94.4 264.9 83.4 100.0 71.0 81.8 104.9 161.1 127.3 205.5 79.1 125.8 75.3 134.5 136.1 164.9 52.3 160.9 45.0 94.5 48.0 52.2 101.2 96.5 46.8 47.8 273.8 51.5 185.1 71.9 56.5 102.9 66.1 64.8 56.6 66.1 71.0 68.7 64.1 64.8 61.5 67.5 68.5 72.3 73.5 60.9 62.2 18.3 210.5 47.0 45.7 31.0 67.7 35.7 45.6 37.5 59.7 41.5 46.9 16.5 31.3 71.9 137.6 74.4 52.8 64.8 3.0 52.9 56.4 60.9 41.9 55.5 41.5 63.4 340.9 47.2 47.9 57.6 124.4 30.0 41.7 42.3 260.3 35.3 41.1 46.4 22.4 182.0 243.8 5.6 25.1 259.9 46.2 81.5 237.0 47.1 73.2 31.7 41.5 77.2 69.6 41.8 236.3 63.3 60.1 69.9 55.1 46.4 6.6 34.6 50.5 27.4 49.9 76.3 44.8 87.2 109.0 59.7 44.9 92.7 GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.2;kidney: 61.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.1;Basal squamous epithelial cells: 104.7;Prostatic glandular cells: 79.0;Squamous epithelial cells: 124.7;Syncytiotrophoblasts: 98.6;Urothelial cells: 79.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "OE19: 1706.0" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in many" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" 5.9 0.1 0.0 0.7 0.4 0.0 14.2 5.6 0.4 13.5 4.5 8.1 11.8 3.3 3.8 60.2 22.3 9.5 1.2 0.2 0.0 61.5 11.1 10.6 0.1 0.0 0.4 1.0 32.7 11.4 6.9 11.9 0.5 14.5 10.0 0.1 25.2 11.6 0.3 39.9 10.8 1.0 0.0 0.5 16.9 1.2 0.1 1.1 6.6 0.1 8.7 7.5 26.2 0.3 12.6 14.4 0.0 0.0 0.0 0.0 19.1 0.0 0.8 0.1 0.5 44.7 24.3 0.0 4.2 0.4 0.9 24.1 0.0 16.1 0.0 0.0 2.1 0.0 6.4 38.5 0.0 0.0 0.0 0.0 15.1 0.2 3.7 2.5 0.1 0.0 0.0 0.0 0.0 11.5 0.2 0.1 4.9 1706.0 3.4 0.1 0.0 18.6 18.5 14.0 9.5 0.1 18.4 370.7 0.1 17.3 14.0 0.0 0.0 0.0 1.1 0.2 0.0 0.2 0.1 1.0 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.6 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.3 0.5 22.4 15.1 0.0 0.9 38.2 77.1 20.0 104.7 0.2 48.2 30.5 2.5 17.2 18.2 22.0 0.0 35.7 0.7 25.6 9.8 35.6 0.0 30.2 5.3 2.6 14.4 0.0 0.3 19.4 27.4 3.1 27.0 41.8 1.3 0.5 0.4 5.1 2.8 0.0 0.0 19.7 40.7 0.0 2.3 0.0 2.8 1.3 5.4 0.0 1.6 0.4 0.0 0.0 0.0 26.7 26.0 1.2 0.3 79.0 28.3 13.8 20.9 0.1 0.0 0.9 2.1 0.4 0.3 124.7 41.9 98.6 1.4 0.0 21.1 79.7 GRIN2A "GluN2A, NMDAR2A" ENSG00000183454 "Glutamate ionotropic receptor NMDA type subunit 2A" Q12879 16 9753404-10182928 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 31.7" "Group enriched" "Detected in some" 13 "Excitatory neurons: 839.8;Inhibitory neurons: 904.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 31.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.4;RPMI-8226: 1.8;U-138 MG: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022725 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022725: " "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-2)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (2.08e-1)" "unprognostic (5.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (4.79e-3)" "unprognostic (2.05e-1)" "unprognostic (3.92e-3)" "unprognostic (3.33e-2)" 0.3 0.3 4.7 0.0 8.4 0.0 0.1 0.0 31.7 0.3 0.0 0.2 0.3 0.3 2.5 1.1 2.1 0.1 3.0 20.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 2.2 0.2 0.3 0.0 0.5 0.2 0.4 0.0 0.0 0.4 2.1 0.1 0.6 0.2 0.2 0.2 0.1 0.4 10.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.3 1.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.4 0.0 31.7 20.0 0.0 0.0 0.0 0.0 0.0 0.1 10.3 0.2 0.0 0.0 16.0 0.0 1.9 2.2 0.5 3.4 10.3 0.3 0.0 18.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2.1 17.2 0.3 0.1 0.5 0.0 0.0 839.8 0.2 0.0 2.7 0.0 0.7 0.0 3.3 0.0 0.3 0.1 1.7 904.7 0.0 0.0 0.3 0.4 15.1 0.9 0.1 0.0 15.9 0.0 15.6 0.0 27.6 65.8 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.9 0.0 0.0 5.4 8.2 10.0 0.2 0.4 0.0 0.0 0.0 0.1 0.3 GSK3A ENSG00000105723 "Glycogen synthase kinase 3 alpha" P49840 19 42226225-42242625 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004422, HPA028423" Approved Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB004422: AB_627680, HPA028423: AB_10612116" "unprognostic (5.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (3.80e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (4.49e-2)" "unprognostic (7.22e-2)" "unprognostic (8.22e-3)" 30.6 43.3 37.5 22.1 44.0 30.7 29.4 33.6 90.2 34.5 13.7 39.4 40.9 38.1 21.7 40.2 31.8 18.7 45.8 47.0 30.9 39.2 30.4 30.4 23.7 39.1 30.9 34.5 29.6 34.4 32.1 19.9 37.6 33.3 21.1 32.6 31.7 25.9 79.2 42.9 37.1 23.0 20.5 31.2 35.4 30.6 38.2 32.9 29.6 42.0 22.7 37.7 33.0 49.5 57.0 102.1 54.3 53.2 30.3 29.5 25.9 42.7 36.1 49.6 46.0 39.0 39.6 41.0 39.6 33.9 44.8 25.6 49.5 51.3 38.5 33.8 74.5 41.5 41.3 42.7 42.7 51.7 54.0 27.2 45.8 41.9 47.7 44.8 46.5 34.7 73.9 63.0 41.1 80.0 87.7 39.0 42.8 84.5 40.0 58.4 33.8 30.4 43.4 76.1 63.7 67.5 52.8 71.6 36.6 42.8 39.5 69.5 40.6 52.0 40.9 31.0 71.9 65.8 82.8 38.7 66.4 49.8 58.2 0.9 0.5 1.4 0.5 0.8 0.9 0.3 0.3 0.7 0.2 0.2 0.2 0.8 1.7 0.3 0.4 0.6 0.5 0.7 37.5 44.0 33.6 90.2 47.0 30.9 39.1 30.9 37.6 20.5 38.2 49.5 45.6 6.4 16.2 5.2 16.4 24.6 17.7 7.3 14.8 40.8 35.0 39.2 12.9 17.2 7.9 16.5 62.6 23.4 31.4 42.3 3.9 15.2 8.6 19.6 21.5 26.6 23.4 28.6 15.1 17.2 25.3 21.3 16.8 25.0 2.5 27.2 18.2 13.9 20.3 60.6 14.9 29.7 6.1 21.3 15.4 14.6 17.7 25.2 16.0 8.4 14.4 41.8 21.6 11.1 12.2 24.2 24.3 16.6 12.6 29.0 45.0 16.0 5.9 47.0 6.6 50.4 27.4 16.4 19.4 20.2 28.1 44.1 20.6 42.6 28.8 30.1 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GSR ENSG00000104687 "Glutathione-disulfide reductase" P00390 8 30678066-30727846 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001538, CAB008632, HPA064806" Approved Supported Cytosol NA NA 81000000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB008632: AB_1616690, HPA001538: AB_1078986, HPA064806: " "unprognostic (1.23e-1)" "prognostic favorable (3.37e-4)" "prognostic favorable (4.08e-5)" "unprognostic (2.89e-3)" "unprognostic (1.62e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (4.15e-2)" "unprognostic (2.83e-2)" "unprognostic (6.92e-3)" "prognostic favorable (1.80e-4)" "unprognostic (2.31e-3)" "unprognostic (2.26e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 13.6 23.3 12.3 18.7 11.1 25.9 11.0 10.6 11.7 28.5 25.8 42.5 54.3 16.0 21.6 37.3 21.6 30.5 25.4 12.9 12.5 45.3 35.8 17.4 23.6 9.5 14.2 23.1 26.5 82.3 14.8 23.5 12.0 35.3 46.6 12.8 25.8 29.4 28.9 12.8 50.8 17.9 10.7 22.1 41.8 11.6 17.6 26.7 16.9 21.3 24.0 22.5 27.7 11.2 49.4 197.8 35.9 40.1 35.8 38.3 29.1 23.4 46.8 31.8 36.7 66.0 31.3 95.8 94.8 32.0 96.1 59.2 62.3 51.1 33.1 22.6 40.7 104.6 67.0 197.8 88.4 38.6 159.7 72.6 28.5 48.9 20.9 33.5 43.3 57.3 73.2 55.1 67.9 44.1 147.1 32.0 65.4 191.9 31.5 43.8 41.9 59.3 56.0 124.3 28.2 31.8 31.2 87.8 58.8 40.7 37.5 32.6 63.8 21.0 34.7 37.3 35.2 20.2 29.4 70.0 51.9 51.8 62.4 32.3 5.9 15.0 5.0 5.4 8.8 3.6 4.5 5.4 6.0 2.3 2.8 3.7 8.2 3.6 7.9 3.9 4.5 3.1 12.3 11.1 10.6 11.7 12.9 12.5 9.5 14.2 12.0 10.7 17.6 11.2 8.2 3.2 20.8 12.7 13.7 4.2 15.2 9.4 52.3 6.7 6.7 5.0 26.8 30.0 15.0 12.9 16.7 17.0 20.3 61.8 9.8 11.4 8.4 61.4 13.4 9.9 34.1 28.6 18.1 19.8 6.3 10.0 33.1 41.3 6.3 64.3 12.1 43.4 18.2 3.3 27.4 51.7 8.2 40.5 5.8 18.9 7.2 22.1 8.8 11.2 20.6 12.6 17.5 12.5 10.0 15.2 32.0 10.9 15.6 27.5 75.7 19.0 11.7 8.0 6.6 7.0 8.6 1.2 3.4 39.6 5.4 6.4 17.3 17.2 47.5 33.5 GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 479.1;liver: 609.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 6.8;Cardiomyocytes: 6.0;Club cells: 6.7;Hepatocytes: 5.5;Kupffer cells: 7.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 63.1" "Region enriched" "Detected in all" 18 "cerebral cortex: 479.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 87.0;HeLa: 96.1;HHSteC: 78.6;hTEC/SVTERT24-B: 73.0;HUVEC TERT2: 62.4;MOLT-4: 115.4;U-266/84: 64.4" "Low region specificity" "Detected in all" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Cytokinetic bridge" "CAB022669: , CAB047357: , HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.22e-2)" "unprognostic (5.35e-2)" "unprognostic (3.87e-3)" "unprognostic (3.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (1.81e-1)" "unprognostic (2.41e-1)" "unprognostic (6.55e-2)" "unprognostic (2.34e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (2.12e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-1)" "unprognostic (4.72e-3)" 55.5 155.7 26.1 17.4 26.4 9.7 56.9 24.9 479.1 61.5 26.9 39.1 27.9 38.1 69.6 152.3 45.8 29.4 30.5 25.9 25.8 37.3 609.6 28.2 1.8 25.5 26.3 178.4 66.8 48.7 33.5 8.7 26.1 47.0 22.4 10.2 43.8 128.6 69.3 73.5 47.3 64.3 25.0 63.6 59.5 57.0 26.6 33.5 27.7 0.0 17.9 127.0 135.2 25.3 0.3 0.6 0.3 1.3 0.0 0.0 0.5 0.0 0.3 0.2 0.4 1.0 7.0 26.9 0.1 41.6 0.0 1.3 0.1 0.6 0.7 0.1 0.4 87.0 96.1 1.7 78.6 0.0 0.7 0.1 0.1 73.0 0.3 48.1 62.4 50.1 0.0 56.8 2.5 0.0 115.4 0.7 54.6 0.1 0.0 0.4 0.6 11.1 9.0 0.1 5.3 0.7 0.0 0.3 0.5 2.6 1.1 44.5 0.2 35.5 2.0 0.9 0.1 45.1 64.4 3.7 30.7 1.1 2.0 2.2 26.1 32.2 28.8 39.1 31.0 30.8 31.4 28.5 77.8 32.5 33.1 32.6 2.0 30.1 17.4 41.1 38.9 28.5 26.1 26.4 24.9 479.1 25.9 25.8 25.5 26.3 26.1 25.0 26.6 25.3 0.3 9.6 6.8 0.0 0.2 1.8 0.6 2.0 0.0 0.1 2.7 1.9 6.0 2.8 6.7 0.0 0.0 0.0 0.8 0.4 0.0 1.2 0.0 0.9 1.9 0.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.5 2.5 0.0 5.0 5.5 0.1 0.0 0.0 0.3 0.0 7.1 2.2 0.4 3.7 0.5 0.0 0.0 0.7 2.4 0.0 0.0 0.0 0.6 0.1 2.2 0.0 0.1 1.9 0.0 5.1 0.0 0.0 0.3 1.4 0.5 0.4 0.0 1.6 0.0 0.8 0.0 0.2 1.8 GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 377.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 802.2;Early spermatids: 2092.4;Late spermatids: 3843.4;Spermatocytes: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 3.4;gdT-cell: 3.1;memory CD4 T-cell: 3.9;memory CD8 T-cell: 2.2;naive CD4 T-cell: 7.8;naive CD8 T-cell: 4.3;T-reg: 1.9" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;T-cells: 7.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 228.4;T-47d: 479.6;WM-115: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Approved Cytosol NA NA 790000 "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017130: , CAB040583: , HPA035190: AB_10795023, HPA055972: AB_2682992" "unprognostic (2.13e-2)" "unprognostic (2.76e-2)" "unprognostic (1.95e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (7.28e-2)" "unprognostic (3.28e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.89e-4)" "unprognostic (3.45e-1)" "unprognostic (1.51e-1)" "unprognostic (2.30e-1)" "unprognostic (6.16e-3)" "unprognostic (1.38e-2)" "unprognostic (1.21e-2)" "unprognostic (1.90e-2)" "unprognostic (3.48e-2)" 38.7 39.0 56.9 11.0 61.1 3.3 83.5 50.3 69.1 52.7 109.7 45.0 46.8 32.1 243.2 53.6 35.1 47.0 74.8 56.9 63.6 188.1 20.0 23.6 6.2 54.4 54.8 120.4 101.0 41.1 33.7 21.6 55.5 47.5 19.9 21.1 22.6 165.9 65.8 57.2 27.8 58.3 57.5 14.1 76.2 377.9 61.6 13.2 57.9 51.2 7.9 57.1 53.2 58.3 0.2 6.9 49.3 0.1 64.5 39.9 8.5 54.3 9.4 58.2 56.2 21.8 1.9 0.1 30.8 27.8 40.1 2.6 10.0 22.3 80.5 0.3 14.9 50.8 152.1 33.9 69.5 0.0 115.2 40.3 27.0 87.8 0.1 63.5 73.1 61.9 4.7 0.6 26.6 30.0 14.5 1.2 5.3 0.2 93.1 0.4 31.9 2.3 16.3 117.1 86.1 46.0 112.5 228.4 10.5 14.1 479.6 75.3 57.9 0.8 20.9 59.6 36.3 7.7 13.1 0.2 0.6 0.1 186.9 0.3 0.1 3.4 3.1 0.1 0.8 0.3 3.9 2.2 0.1 0.2 7.8 4.3 0.9 0.7 0.1 0.5 1.9 1.5 56.9 61.1 50.3 69.1 56.9 63.6 54.4 54.8 55.5 57.5 61.6 58.3 22.2 6.4 11.5 18.3 7.0 143.5 97.2 104.4 50.1 17.5 196.1 176.8 88.0 50.1 35.9 222.5 6.2 16.3 8.7 17.3 802.2 88.0 2092.4 51.4 40.6 32.9 50.4 33.0 7.5 149.5 9.0 131.6 43.8 93.6 9.5 22.7 58.2 14.2 10.6 15.2 8.0 24.9 28.5 13.9 54.1 3843.4 385.5 15.1 60.5 2.8 3.5 247.5 2.1 14.6 1.7 126.4 32.5 276.1 3.4 53.7 116.9 38.9 5.4 19.2 190.7 23.8 94.4 1177.6 54.4 71.9 107.4 10.3 24.4 121.4 44.1 80.8 GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583742-67586656 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2087.9" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 4033.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 4998.3;OE19: 7810.3" "Low region specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol No No 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Mitochondria, Cytosol" "HPA019779: AB_1849799, HPA019869: AB_1849801" "unprognostic (9.81e-2)" "unprognostic (6.52e-2)" "unprognostic (7.24e-2)" "unprognostic (2.72e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-3)" "unprognostic (3.27e-1)" "unprognostic (4.98e-2)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (2.14e-3)" "unprognostic (9.37e-2)" "unprognostic (5.72e-2)" "unprognostic (7.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.72e-3)" "unprognostic (1.48e-1)" 290.5 276.2 346.8 232.1 370.3 601.3 288.7 358.9 425.7 641.9 695.8 329.6 394.6 331.9 280.3 2087.9 647.5 435.8 367.2 341.4 381.9 567.7 45.1 468.3 321.8 375.7 379.2 306.9 340.9 737.4 320.2 326.9 378.5 291.7 197.1 137.9 541.2 780.4 355.0 731.4 321.7 214.2 367.0 257.2 535.5 45.8 378.1 296.9 579.0 312.5 380.8 526.5 946.2 377.7 1202.5 1599.4 763.7 1198.9 577.8 645.2 705.3 511.3 678.1 761.2 589.3 2956.3 1225.0 3.3 1144.7 813.5 683.7 1707.8 2073.9 2248.5 214.4 848.0 765.3 59.9 1107.6 0.5 852.2 400.3 667.6 807.2 4998.3 609.9 583.3 560.9 1160.2 847.2 1318.2 321.8 605.7 4.3 918.2 1100.6 1475.2 7810.3 681.3 844.8 129.6 3.8 1236.8 3.6 260.6 754.3 719.1 230.9 2394.0 598.2 3.6 656.3 634.5 351.6 883.8 740.6 378.6 200.0 1353.9 447.1 400.0 652.4 747.8 56.0 3145.4 246.6 720.0 2470.8 271.9 509.2 322.4 597.7 3582.7 476.3 267.8 466.5 130.5 1443.8 1608.5 1435.1 363.3 3948.4 346.8 370.3 358.9 425.7 341.4 381.9 375.7 379.2 378.5 367.0 378.1 377.7 466.7 1153.8 872.3 25.5 296.8 865.6 1914.8 3813.8 767.2 170.0 628.7 838.3 297.3 987.9 2763.5 1230.4 33.3 2116.8 372.4 655.0 1805.9 1811.9 4.9 1381.0 589.0 431.4 368.2 166.3 6.8 1444.4 1703.9 710.5 781.9 1020.9 269.9 795.0 382.3 10.5 861.2 70.7 10.1 992.4 1930.7 597.9 1090.3 25.5 572.3 703.5 1531.5 27.2 2166.5 558.5 459.3 17.6 38.4 1412.1 948.9 400.2 591.6 2266.2 844.4 3495.5 3715.4 274.4 361.6 401.3 941.7 4.8 54.9 4033.7 1061.7 1645.5 342.5 527.8 1118.5 3418.6 GTF2H1 "BTF2, P62, TFIIH" ENSG00000110768 "General transcription factor IIH subunit 1" P32780 11 18322295-18367045 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004637, HPA046660" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB004637: AB_425470, HPA046660: AB_2679743" "unprognostic (2.25e-1)" "unprognostic (2.33e-1)" "unprognostic (9.78e-2)" "unprognostic (2.38e-1)" "unprognostic (2.63e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (5.98e-9)" "unprognostic (7.71e-2)" "unprognostic (4.24e-2)" "unprognostic (2.81e-1)" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (7.42e-3)" "unprognostic (8.31e-2)" "unprognostic (1.24e-1)" "unprognostic (7.90e-2)" "unprognostic (2.94e-1)" 19.0 18.2 6.0 7.6 6.4 4.7 18.2 7.6 7.2 16.5 10.0 17.9 7.5 15.6 8.2 19.4 14.6 9.4 14.9 6.7 6.0 16.2 17.2 13.9 10.9 5.5 5.8 19.2 17.9 8.2 13.8 10.0 5.6 15.8 8.2 13.1 18.7 10.0 16.6 20.0 14.7 8.4 5.8 17.2 15.2 26.5 6.1 8.8 16.0 8.3 11.1 17.7 16.9 7.6 14.7 13.3 11.0 15.5 25.1 20.1 13.7 21.8 23.6 19.0 21.9 13.9 5.6 24.9 8.4 22.4 27.2 19.8 19.1 20.1 24.1 11.0 18.5 15.9 13.4 14.1 35.8 30.7 16.5 22.4 23.8 11.7 37.3 15.7 17.3 12.8 25.2 12.6 27.7 13.6 15.6 23.3 9.8 24.7 19.8 16.1 23.4 11.3 15.3 19.6 12.5 13.5 17.8 17.1 27.0 9.4 8.8 17.5 12.6 24.9 12.2 45.3 17.8 6.3 16.0 17.7 21.5 24.0 24.4 11.0 5.0 5.4 3.8 5.0 4.2 5.4 4.8 4.3 5.4 5.7 5.8 4.7 3.5 7.5 6.0 2.9 5.2 4.2 6.0 6.4 7.6 7.2 6.7 6.0 5.5 5.8 5.6 5.8 6.1 7.6 27.8 16.0 18.2 19.2 26.1 48.3 22.7 22.2 39.9 17.3 23.4 20.6 28.3 22.8 21.9 11.0 20.9 26.1 26.8 14.7 7.9 25.2 50.2 19.0 17.7 21.6 7.7 26.1 32.1 30.5 27.5 27.1 21.4 20.2 18.3 20.0 22.1 13.9 25.2 21.9 29.9 12.9 14.2 20.8 27.2 46.1 17.1 28.8 23.2 20.6 25.9 23.4 25.7 24.1 29.4 28.8 10.5 16.1 25.7 23.4 18.6 25.1 23.6 21.2 6.6 23.4 23.2 84.8 30.1 37.6 51.7 28.2 20.4 29.2 16.8 26.8 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 213.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 28.4 18.2 11.0 22.3 12.3 84.2 80.9 12.0 16.1 26.7 14.3 38.2 36.1 26.2 41.8 16.4 24.6 27.6 19.6 10.7 11.5 25.1 104.0 35.7 25.6 13.2 12.2 19.9 33.6 30.3 12.6 48.2 13.2 20.2 41.9 9.7 32.9 21.2 10.9 18.8 29.8 19.1 11.9 34.0 38.1 19.5 13.0 22.7 27.7 14.4 24.0 27.3 15.4 13.5 67.0 26.5 25.2 56.3 80.9 49.1 35.3 21.3 56.8 45.0 42.1 37.0 67.8 30.9 32.3 26.8 24.1 27.5 16.5 25.1 26.8 27.3 34.1 41.5 40.9 27.3 39.7 89.6 67.1 33.4 26.7 26.3 33.3 54.5 39.3 18.0 63.2 213.5 30.5 50.3 34.2 92.0 17.9 103.0 21.0 34.4 55.9 172.4 29.4 42.8 36.2 32.7 55.6 129.1 72.3 29.9 71.1 88.8 28.5 55.3 49.3 21.8 53.6 119.6 151.9 50.0 41.0 116.3 68.3 26.0 80.1 65.7 32.0 103.0 28.4 27.7 24.7 28.4 80.5 22.6 16.8 19.5 13.2 46.6 93.5 34.2 34.5 51.4 11.0 12.3 12.0 16.1 10.7 11.5 13.2 12.2 13.2 11.9 13.0 13.5 53.1 51.3 58.7 10.1 33.0 18.0 32.0 51.9 29.0 12.2 26.1 19.9 12.2 48.6 48.9 29.5 8.4 81.9 32.6 52.2 5.9 41.1 59.1 28.9 26.5 39.7 43.0 47.1 12.3 30.3 61.2 49.5 49.5 49.4 36.8 38.3 37.9 72.7 126.4 16.8 10.6 51.6 30.5 88.1 33.2 46.7 43.2 78.0 39.2 14.0 44.8 28.0 20.6 8.5 14.2 29.4 49.5 28.6 87.5 25.3 50.6 26.8 43.2 20.1 26.3 27.1 26.0 49.6 31.0 16.0 14.8 66.9 32.2 24.4 44.3 29.6 H2AC6 "H2AFL, HIST1H2AC" ENSG00000180573 "H2A clustered histone 6" Q93077 6 26124145-26139116 "Cancer-related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.4" "Cell type enhanced" "Detected in some" "Adipocytes: 10.9;Cardiomyocytes: 23.3;Cytotrophoblasts: 14.3;Extravillous trophoblasts: 28.5;Hofbauer cells: 16.2;Syncytiotrophoblasts: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1552.9" "Lineage enriched" "Detected in all" 14 "granulocytes: 1552.9" "Cell line enhanced" "Detected in many" "U-266/84: 61.0" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (4.89e-2)" "unprognostic (1.97e-1)" "unprognostic (7.15e-3)" "unprognostic (1.34e-1)" "unprognostic (4.70e-1)" "unprognostic (1.33e-1)" "unprognostic (3.25e-1)" "unprognostic (1.37e-1)" "unprognostic (8.16e-2)" "unprognostic (2.57e-1)" "unprognostic (1.61e-3)" "unprognostic (1.75e-1)" "unprognostic (1.19e-2)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (5.89e-3)" 14.0 12.7 26.8 5.0 39.2 12.9 10.7 38.1 38.5 21.6 24.1 13.1 11.5 4.7 11.3 28.1 10.8 10.3 11.2 34.5 41.7 21.5 30.2 22.9 5.5 37.9 34.4 12.7 7.2 0.9 10.5 5.2 33.9 26.0 5.3 3.9 10.8 2.1 20.2 16.7 13.2 2.1 52.1 21.2 13.8 4.7 30.6 18.1 12.7 4.7 2.0 12.0 28.6 65.4 13.2 30.7 0.1 0.0 14.4 8.8 1.5 8.4 2.4 4.0 4.1 10.3 3.7 0.0 36.8 4.2 1.8 4.0 0.0 0.8 2.7 18.4 3.5 1.8 21.5 3.8 10.8 0.7 8.8 26.5 4.5 1.4 4.5 10.9 1.4 0.7 23.1 11.9 3.9 20.0 2.9 3.4 1.3 10.4 13.9 2.3 0.2 25.6 13.2 8.7 3.2 3.2 29.5 4.0 13.4 7.1 33.3 2.4 3.2 6.9 20.5 3.6 1.7 32.7 61.0 4.7 2.0 28.4 1.1 440.2 31.9 324.6 28.0 24.6 25.7 61.7 29.7 19.4 28.3 109.5 34.9 19.6 1552.9 33.7 65.6 79.9 33.8 662.0 26.8 39.2 38.1 38.5 34.5 41.7 37.9 34.4 33.9 52.1 30.6 65.4 10.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 14.3 7.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 28.5 4.3 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 75.9 1.1 0.0 0.0 0.0 H3-3A "H3.3A, H3F3, H3F3A" ENSG00000163041 "H3.3 histone A" P84243 1 226061851-226072019 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 600.6;Cytotrophoblasts: 1411.0;Extravillous trophoblasts: 2181.9;Hofbauer cells: 1487.3;Syncytiotrophoblasts: 1616.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4487.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 4487.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011481, CAB037178, HPA042570" Supported Supported Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB011481: AB_880446, CAB037178: AB_532248, HPA042570: AB_2678056" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (2.19e-3)" "unprognostic (2.83e-2)" "unprognostic (3.74e-1)" "unprognostic (9.83e-3)" "unprognostic (4.71e-2)" "unprognostic (1.77e-3)" "unprognostic (3.69e-2)" "unprognostic (1.29e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (3.66e-2)" "unprognostic (8.03e-3)" "unprognostic (2.21e-3)" "unprognostic (6.03e-2)" 409.6 440.4 240.3 662.2 255.8 2033.8 594.8 262.4 343.4 544.2 244.8 708.3 655.2 492.2 721.3 595.8 565.3 487.7 500.1 229.1 252.3 457.9 537.9 438.9 793.5 273.8 247.1 453.0 435.4 499.7 270.0 490.0 274.4 474.8 790.0 271.6 586.9 382.0 337.1 617.2 672.5 468.6 272.4 539.1 547.2 255.9 246.8 1239.6 480.5 435.5 894.6 597.6 409.0 295.7 751.2 417.0 1589.6 910.2 432.9 498.9 1186.2 337.3 416.2 547.8 429.0 446.2 1214.5 715.3 731.0 427.9 273.5 684.4 802.4 631.9 535.0 445.9 1371.0 889.5 569.9 595.2 427.8 901.4 1026.6 465.6 715.8 385.3 502.1 743.0 826.8 915.7 1271.3 1125.2 626.2 433.8 1791.8 1504.6 2163.0 1881.1 815.7 1286.9 1110.4 1871.4 1159.6 784.3 1542.1 2279.8 991.0 1227.4 842.4 882.3 1399.1 2103.7 471.4 397.1 527.2 532.6 1024.0 523.6 643.4 1178.4 380.2 853.2 874.1 869.5 1043.6 1486.1 378.9 830.2 385.9 722.1 405.2 415.8 791.8 661.7 375.0 423.1 4487.2 442.5 945.8 635.2 636.8 1364.8 240.3 255.8 262.4 343.4 229.1 252.3 273.8 247.1 274.4 272.4 246.8 295.7 600.6 0.0 0.0 0.0 202.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 1411.0 449.2 0.0 0.0 0.0 0.0 0.0 0.0 109.5 0.0 0.0 0.0 0.0 2181.9 188.0 0.0 0.0 0.0 0.0 0.0 0.0 1487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 218.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 1616.9 75.3 0.0 0.0 0.0 H3-3B "H3.3B, H3F3B" ENSG00000132475 "H3.3 histone B" P84243 17 75776434-75785893 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 4220.9" "Cell type enhanced" "Detected in some" "Adipocytes: 1321.3;Cytotrophoblasts: 1625.3;dendritic cells: 844.9;Extravillous trophoblasts: 1626.9;Hofbauer cells: 1908.9;Syncytiotrophoblasts: 3503.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 21089.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 21089.7" "Low cell line specificity" "Detected in all" "CAB037166, CAB037187, CAB037221, HPA042570" Supported Enhanced Nucleoplasm NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB037166: AB_2115285, CAB037187: AB_477069, CAB037221: AB_477076, HPA042570: AB_2678056" "unprognostic (1.66e-1)" "unprognostic (8.42e-3)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.95e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.64e-1)" "unprognostic (5.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.26e-3)" "unprognostic (9.20e-2)" "unprognostic (4.81e-2)" "unprognostic (2.33e-1)" "unprognostic (1.99e-1)" 607.2 369.9 223.8 532.5 262.6 4220.9 628.9 264.4 288.8 741.2 186.6 415.4 329.9 507.4 180.3 798.6 585.7 467.9 312.8 210.7 226.0 438.3 380.2 553.2 509.1 268.7 241.9 1166.0 578.0 341.1 357.5 427.1 242.8 348.2 223.1 299.8 519.2 237.1 332.5 1153.2 407.5 322.9 253.7 449.9 393.0 654.3 246.0 464.0 500.7 155.6 296.2 545.3 675.2 316.1 1386.5 1194.2 490.0 486.1 273.3 424.9 675.1 636.7 557.1 764.8 609.3 1290.7 952.6 683.6 593.1 373.2 539.5 530.0 390.5 881.0 432.0 375.9 883.0 612.8 668.2 1112.0 615.7 1029.2 755.0 467.3 534.2 785.6 1004.7 339.3 582.5 437.8 885.6 1193.0 399.4 2015.3 1492.3 859.5 394.8 442.8 1322.8 1091.7 894.2 746.6 607.3 803.5 988.1 1096.0 645.8 933.7 1402.2 259.3 734.2 1091.3 549.1 1359.7 1205.2 595.2 1721.1 1431.3 932.2 843.5 720.5 967.6 761.1 7991.0 3667.6 10060.5 2613.4 3365.8 2482.2 3199.5 2474.2 2478.9 3218.1 2813.7 2635.4 2173.4 21089.7 3240.7 3199.0 3294.6 2999.0 9615.0 223.8 262.6 264.4 288.8 210.7 226.0 268.7 241.9 242.8 253.7 246.0 316.1 1321.3 0.0 0.0 0.0 294.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 398.6 0.0 0.0 0.0 0.0 1625.3 844.9 0.0 0.0 0.0 0.0 0.0 0.0 172.3 0.0 0.0 0.0 0.0 1626.9 485.1 0.0 0.0 0.0 0.0 0.0 0.0 1908.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 257.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 314.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 377.9 0.0 0.0 0.0 0.0 3503.3 211.7 0.0 0.0 0.0 H3C2 "H3/l, H3FL, HIST1H3B" ENSG00000286522 "H3 clustered histone 2" P68431 6 26031589-26032099 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "bone marrow: 6.4;brain: 4.1;choroid plexus: 1.6;lymphoid tissue: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 8.4" HPA042570 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: U-266 - Nucleosome" "HPA042570: AB_2678056" 0.0 0.1 1.3 0.1 0.8 6.4 0.1 0.3 1.0 0.0 1.6 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.5 1.0 2.2 0.0 0.0 0.0 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 4.1 1.7 0.1 0.2 0.0 0.0 3.2 1.2 2.7 1.1 2.5 0.0 0.2 0.0 0.1 0.4 0.4 0.4 0.6 0.9 2.0 1.4 0.2 0.7 0.4 0.9 0.7 0.9 1.4 2.7 2.1 4.0 0.8 0.0 1.6 1.4 1.6 0.0 0.3 0.0 0.0 0.5 0.6 4.3 3.8 0.6 0.6 5.0 5.0 2.0 0.5 1.9 2.9 1.8 5.6 0.3 0.0 1.3 1.1 3.9 1.0 0.3 0.0 1.8 1.0 0.9 0.8 3.1 0.4 1.2 6.3 8.4 2.6 2.1 2.9 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 1.3 0.8 0.3 1.0 0.6 0.7 1.0 2.2 2.2 0.6 4.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H4C9 "H4/m, H4FM, HIST1H4I" ENSG00000276180 "H4 clustered histone 9" P62805 6 27138588-27139881 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 75.5;SiHa: 43.8;U-2 OS: 73.3;U-266/84: 78.9" HPA042201 Approved NA NA 25000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA042201: AB_2677898" "unprognostic (2.49e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.97e-2)" "unprognostic (2.51e-2)" "unprognostic (2.26e-1)" "unprognostic (2.25e-1)" "unprognostic (1.07e-1)" "unprognostic (2.16e-1)" "unprognostic (2.85e-1)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (6.28e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-1)" "unprognostic (2.02e-2)" 1.2 3.3 0.3 3.7 0.5 3.2 0.6 0.2 1.5 0.6 0.0 1.9 3.8 2.0 0.0 2.6 0.5 2.3 1.5 0.6 0.6 0.5 2.7 1.7 4.2 0.8 0.8 1.6 3.7 0.0 0.3 2.5 0.7 3.0 0.2 0.2 2.4 0.0 0.4 1.3 4.0 0.0 0.9 3.5 4.0 2.7 0.6 1.0 3.6 0.0 0.1 1.4 1.1 0.7 4.2 8.5 4.6 3.0 3.2 0.4 5.1 8.1 0.3 0.4 0.3 8.3 6.0 1.3 22.7 0.1 12.5 6.5 0.8 0.2 0.2 5.8 12.5 3.0 13.4 0.4 0.5 2.5 14.8 1.1 0.3 0.0 0.4 7.7 0.4 2.9 75.5 22.2 0.0 12.9 3.8 5.6 1.9 30.2 5.3 3.4 2.7 21.3 0.2 2.2 15.4 5.6 43.8 19.8 5.1 5.2 37.9 1.8 2.7 5.6 73.3 6.8 0.8 22.2 78.9 14.5 3.3 16.8 5.9 14.4 3.0 17.4 1.7 2.4 1.4 5.3 1.5 1.7 3.0 6.6 1.8 1.9 16.5 3.0 5.9 6.4 4.1 3.5 0.3 0.5 0.2 1.5 0.6 0.6 0.8 0.8 0.7 0.9 0.6 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 HDAC10 DKFZP761B039 ENSG00000100429 "Histone deacetylase 10" Q969S8 22 50245183-50251405 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, DNA damage, DNA recombination, DNA repair" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB045977 Supported NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB045977: AB_11124034" "unprognostic (1.53e-1)" "prognostic favorable (4.46e-4)" "unprognostic (1.43e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (6.15e-3)" "unprognostic (5.48e-2)" "unprognostic (3.28e-1)" "unprognostic (2.56e-2)" "prognostic favorable (9.25e-4)" "unprognostic (4.93e-2)" "prognostic unfavorable (4.74e-11)" "unprognostic (2.21e-2)" "unprognostic (2.52e-2)" "unprognostic (1.43e-2)" "unprognostic (1.38e-3)" 8.9 9.8 4.9 6.0 4.8 9.6 7.1 3.6 10.3 9.3 5.4 9.9 6.6 6.8 1.2 10.7 8.0 3.9 4.9 5.1 4.5 11.5 16.8 8.5 6.7 5.1 4.5 7.6 11.2 2.2 13.2 3.3 4.5 10.8 1.5 0.2 8.7 2.8 5.1 9.2 12.6 1.9 3.9 17.2 11.4 2.2 5.1 4.2 9.5 0.5 2.8 7.2 8.1 4.1 6.1 3.3 0.9 5.0 4.2 3.3 11.4 4.2 3.4 2.3 1.4 6.4 6.6 4.0 5.7 3.1 2.2 10.2 2.1 5.9 0.5 5.4 5.7 8.5 10.1 10.4 7.5 10.9 27.0 7.0 4.4 2.3 1.3 4.8 4.2 7.8 6.3 6.1 2.0 18.7 5.8 25.9 2.0 6.5 7.4 13.4 3.3 24.6 3.8 10.5 2.7 6.5 4.2 1.4 7.2 1.2 10.8 15.8 7.4 3.9 5.7 6.7 2.5 7.8 2.6 3.6 6.4 6.7 2.8 0.4 1.6 2.5 0.7 1.8 0.6 0.4 0.3 0.5 1.3 0.4 0.3 0.3 0.8 0.5 1.0 1.2 0.6 1.1 4.9 4.8 3.6 10.3 5.1 4.5 5.1 4.5 4.5 3.9 5.1 4.1 13.9 0.0 3.4 12.1 17.7 8.7 4.8 10.3 9.1 5.7 14.3 13.6 0.6 12.8 6.8 14.7 16.7 11.6 28.6 25.4 7.9 6.3 3.3 9.3 6.9 8.5 20.9 8.4 8.9 3.8 16.2 8.1 32.6 9.0 5.1 16.6 10.0 7.9 21.1 0.0 10.6 17.3 6.1 20.0 13.3 8.3 11.1 19.9 8.8 4.7 18.1 2.9 20.6 3.5 2.4 6.1 17.8 7.9 12.3 3.4 29.2 16.3 14.3 6.5 0.0 3.0 6.3 1.0 2.3 13.1 9.5 10.3 26.0 13.5 18.3 4.4 HDAC2 "KDAC2, RPD3, YAF1" ENSG00000196591 "Histone deacetylase 2" Q92769 6 113933028-114011308 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005054, HPA011727" Supported Supported Nucleoplasm NA NA 25000 "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "CAB005054: AB_562295, HPA011727: AB_1850540" "prognostic unfavorable (7.07e-4)" "unprognostic (1.44e-1)" "unprognostic (2.67e-1)" "unprognostic (2.56e-2)" "unprognostic (2.61e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (5.39e-10)" "unprognostic (2.03e-1)" "unprognostic (2.63e-2)" "unprognostic (9.00e-2)" "unprognostic (2.01e-1)" "unprognostic (3.92e-1)" "unprognostic (1.84e-2)" "unprognostic (1.96e-1)" "unprognostic (2.42e-1)" "unprognostic (9.80e-2)" "unprognostic (3.51e-1)" 35.9 42.7 26.6 37.4 31.5 63.4 54.8 32.8 40.0 45.2 22.3 48.0 34.4 57.3 53.4 43.3 48.7 34.6 41.1 26.7 34.7 46.3 34.6 33.0 42.6 31.2 29.5 53.4 37.1 45.7 35.9 56.1 31.2 47.0 53.6 37.2 34.3 45.3 48.6 46.1 36.7 54.3 28.8 35.9 40.5 76.7 31.1 68.5 45.6 43.4 52.1 63.2 37.5 37.5 126.7 84.9 387.1 224.3 97.7 110.5 162.6 146.6 119.0 168.5 200.1 226.3 90.1 103.6 119.0 132.5 173.1 96.6 266.0 148.1 281.4 148.9 185.0 249.2 102.1 131.8 129.7 256.1 107.7 90.0 97.6 180.0 167.2 164.4 199.6 179.2 326.4 101.6 282.7 105.5 231.9 229.6 220.0 133.4 116.3 155.0 193.0 95.2 174.4 148.9 258.3 219.1 115.9 107.5 127.7 231.4 78.6 294.0 163.2 107.0 122.9 113.7 246.9 80.6 113.9 244.6 90.9 242.6 185.3 43.5 39.0 42.1 28.0 38.6 37.3 37.0 34.0 30.3 51.0 31.4 41.8 39.1 23.1 39.8 50.2 44.2 36.0 37.2 26.6 31.5 32.8 40.0 26.7 34.7 31.2 29.5 31.2 28.8 31.1 37.5 40.2 57.7 57.8 13.4 51.4 192.1 91.3 152.6 85.4 31.0 61.0 54.6 64.0 25.8 116.4 53.3 4.2 157.7 42.6 43.5 43.0 154.9 86.8 74.3 91.6 73.8 100.5 129.4 29.9 105.0 140.7 76.2 53.5 63.2 55.1 103.9 50.0 31.9 102.0 15.2 26.3 73.4 175.0 64.1 89.8 109.1 83.0 63.3 83.6 26.2 107.7 30.9 33.0 29.1 34.0 133.6 51.3 67.4 56.2 90.0 37.4 71.7 98.7 28.1 39.5 94.7 88.0 199.0 215.5 96.5 193.1 207.7 45.5 53.9 94.6 100.5 HDAC5 "FLJ90614, KIAA0600, NY-CO-9" ENSG00000108840 "Histone deacetylase 5" Q9UQL6 17 44076746-44123702 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 118.9;Syncytiotrophoblasts: 218.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019400, HPA030991" Approved Supported "Nuclear speckles,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear speckles" "Golgi apparatus, Cytosol" "CAB019400: AB_2116626, HPA030991: AB_10795286" "unprognostic (1.30e-2)" "prognostic favorable (6.14e-4)" "unprognostic (6.65e-2)" "unprognostic (8.06e-2)" "unprognostic (3.49e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (8.80e-3)" "unprognostic (3.80e-2)" "unprognostic (2.37e-2)" "unprognostic (4.91e-3)" "unprognostic (4.30e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.51e-2)" "unprognostic (3.11e-1)" "unprognostic (6.00e-2)" "unprognostic (1.76e-2)" 30.8 24.7 39.3 10.9 33.5 20.7 28.8 48.8 48.5 40.6 3.3 36.3 11.6 33.2 15.5 45.1 34.1 15.9 53.5 40.4 31.6 24.8 17.4 33.6 14.0 37.6 41.1 45.0 22.5 31.5 48.1 22.6 35.1 29.2 7.3 24.3 22.9 15.1 77.5 71.3 22.9 14.8 22.4 26.4 24.0 19.7 40.0 10.4 30.8 28.6 11.6 29.2 37.0 50.3 8.7 5.5 14.9 3.5 28.2 21.7 53.6 22.8 56.1 11.3 18.1 12.3 9.1 13.5 9.0 54.4 16.5 6.9 17.6 9.8 4.7 21.2 28.7 26.3 18.6 28.6 12.2 8.7 35.7 31.2 16.5 12.8 15.8 19.0 9.3 10.6 20.0 26.5 65.5 6.7 14.3 26.2 16.4 6.7 13.0 54.7 41.6 35.4 1.2 3.8 38.6 20.3 6.7 27.6 31.2 21.8 39.3 49.6 5.1 27.8 17.5 6.6 11.7 43.6 39.7 16.2 16.0 10.7 13.4 11.6 9.2 9.7 5.4 13.5 3.8 7.2 4.3 5.4 11.1 7.5 4.5 4.0 20.9 4.5 16.8 9.7 4.1 7.3 39.3 33.5 48.8 48.5 40.4 31.6 37.6 41.1 35.1 22.4 40.0 50.3 24.0 12.8 13.7 11.1 20.4 29.2 32.3 9.0 26.2 87.8 23.8 21.3 27.1 30.0 11.9 20.2 118.9 21.9 19.6 22.4 21.5 17.2 20.2 17.1 10.7 22.1 46.0 9.3 18.9 8.7 53.1 24.1 10.2 25.1 12.6 47.0 24.3 9.3 22.7 82.4 31.0 14.9 6.1 18.5 17.8 10.0 48.4 29.8 14.2 12.2 16.5 18.9 11.3 14.1 26.2 11.5 16.5 43.6 14.2 41.2 21.5 7.3 12.4 60.4 65.7 31.8 40.1 4.2 32.7 28.1 32.8 218.1 17.0 29.9 11.3 25.3 HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 2680.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 497.6;U-266/70: 533.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" "CAB037041: AB_1840910, CAB037104: AB_1840912, HPA040754: AB_10794068, HPA041219: AB_10794268" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (8.64e-2)" "unprognostic (3.93e-3)" "unprognostic (3.39e-1)" "unprognostic (5.00e-3)" "unprognostic (1.17e-1)" "unprognostic (9.69e-3)" "unprognostic (3.33e-1)" "unprognostic (2.56e-1)" "unprognostic (2.84e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.41e-9)" "unprognostic (1.06e-1)" "unprognostic (3.93e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-3)" 75.3 108.4 68.4 102.0 70.6 113.6 128.9 73.7 92.6 127.1 99.0 149.5 98.2 65.7 220.2 53.2 86.5 77.8 92.0 67.9 77.9 193.1 193.0 92.0 114.1 77.3 72.8 188.8 377.0 206.9 78.8 97.1 75.2 213.0 141.8 39.7 170.0 102.0 102.9 58.7 84.9 77.8 78.4 114.8 144.1 25.0 74.6 58.0 213.6 120.9 246.6 94.5 45.0 82.8 28.6 30.9 29.8 61.8 66.9 86.9 105.2 65.9 104.6 83.5 64.9 43.1 63.5 115.0 82.7 64.6 84.6 47.9 51.0 23.3 82.4 67.1 30.8 9.9 48.3 156.3 364.6 21.1 49.5 106.0 219.2 38.0 119.6 100.4 64.4 125.9 15.9 159.6 236.3 24.1 39.8 42.7 19.1 164.8 68.9 27.0 74.9 497.6 179.8 31.8 32.7 37.5 57.5 278.8 308.2 41.9 31.3 77.4 40.0 34.8 34.4 30.8 26.8 533.9 191.0 182.6 49.3 28.7 46.4 224.0 291.2 139.5 113.2 238.1 124.0 383.2 120.1 149.7 230.6 340.4 77.2 117.8 215.9 179.6 175.0 915.5 263.8 417.7 68.4 70.6 73.7 92.6 67.9 77.9 77.3 72.8 75.2 78.4 74.6 82.8 316.4 70.5 105.9 16.6 964.5 364.0 561.8 316.3 203.7 134.6 191.3 185.2 221.5 91.5 193.4 71.7 281.5 131.9 577.3 369.1 170.2 192.7 73.3 162.5 121.3 199.8 434.4 40.8 29.9 197.7 182.4 223.8 251.8 260.5 151.8 108.8 134.2 164.0 194.7 47.1 32.2 569.7 290.9 241.6 395.9 251.6 104.1 507.7 948.0 88.1 197.0 94.3 81.4 21.1 30.7 144.8 336.5 95.5 2680.7 447.4 156.1 209.0 95.6 117.1 98.6 178.8 215.6 54.7 10.6 146.6 255.3 693.8 342.6 137.4 311.4 456.8 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 311.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 23.8;Fibroblasts: 95.8;Hepatic stellate cells: 25.0;Muller glia cells: 36.2;Smooth muscle cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.0" "Cell line enhanced" "Detected in some" "ASC TERT1: 171.6;HHSteC: 135.8;HL-60: 82.4;hTEC/SVTERT24-B: 87.4;Karpas-707: 240.7;U-87 MG: 62.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" NA NA 4110000 14000 "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 2: Karpas-707 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" 7.9 19.8 1.6 6.3 3.3 12.3 5.2 1.5 7.8 7.2 1.8 4.4 2.6 8.1 3.6 2.9 5.4 16.6 4.7 2.9 3.6 11.8 30.3 19.5 2.2 3.6 2.3 1.8 2.1 2.1 2.4 311.9 4.3 7.2 3.4 14.2 2.4 6.4 0.8 0.9 2.3 7.1 1.8 6.5 3.9 2.4 2.9 1.5 5.6 3.9 1.5 10.4 6.3 3.3 0.0 0.0 0.1 0.0 21.6 171.6 0.1 0.7 33.4 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.1 6.0 0.0 0.0 135.8 82.4 0.4 41.4 0.0 87.4 0.3 0.0 2.2 0.0 0.1 240.7 0.6 0.0 0.0 56.4 0.0 0.0 0.2 0.8 0.0 7.5 0.0 0.0 0.2 9.3 0.0 0.1 0.0 0.2 0.0 3.5 0.4 2.0 0.0 0.1 0.0 0.1 0.0 0.0 62.6 16.9 0.1 94.0 15.2 3.9 0.0 18.7 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 3.2 0.0 17.3 1.0 0.0 4.3 1.6 3.3 1.5 7.8 2.9 3.6 3.6 2.3 4.3 1.8 2.9 3.3 6.2 0.0 4.1 16.3 0.0 1.0 0.2 0.0 1.8 0.2 0.3 0.5 1.3 1.5 0.6 0.0 0.0 5.6 0.0 0.0 0.0 0.0 15.2 1.0 23.8 6.2 0.0 2.1 0.3 0.0 4.9 95.8 0.5 0.9 1.3 0.0 25.0 0.5 18.4 0.0 22.4 0.0 0.0 12.5 1.9 2.3 18.3 14.0 1.8 7.5 10.5 36.2 1.0 0.0 0.1 0.0 0.0 10.9 0.3 0.4 0.0 0.0 0.0 0.7 13.1 0.9 26.2 0.2 0.3 0.3 0.1 12.0 0.6 1.3 0.0 0.4 HGFAC "HGFA, HGFAP" ENSG00000109758 "HGF activator" Q04756 4 3441968-3449486 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "liver: 217.1" "Group enriched" "Detected in some" 5 "Early spermatids: 85.6;Hepatocytes: 72.0;Late spermatids: 165.9" "Cancer enriched" "Detected in some" 22 "liver cancer: 26.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA058279, HPA059076" Enhanced "Secreted to blood" NA NA 7590000 9300000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "HPA058279: AB_2683665, HPA059076: AB_2683898" "unprognostic (2.70e-2)" "unprognostic (8.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-2)" "unprognostic (2.85e-3)" "unprognostic (5.37e-3)" "unprognostic (5.90e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-3)" "unprognostic (5.52e-2)" "prognostic unfavorable (9.31e-4)" "unprognostic (2.87e-1)" "unprognostic (2.24e-1)" "unprognostic (9.49e-2)" "unprognostic (3.74e-4)" 0.0 0.0 1.5 0.0 2.3 0.0 0.1 2.2 2.6 0.5 0.7 0.2 0.0 0.2 0.2 0.0 0.3 0.0 0.1 1.3 0.6 0.6 217.1 0.1 0.0 0.9 0.6 0.1 0.1 0.0 0.7 0.0 0.9 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.1 3.8 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 2.2 2.6 1.3 0.6 0.9 0.6 0.9 0.5 0.8 0.6 0.1 0.0 0.0 1.3 0.2 0.5 0.1 0.0 0.0 0.0 0.2 0.0 0.5 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 85.6 0.5 0.2 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.4 0.0 4.4 2.2 72.0 0.0 3.3 3.9 0.0 0.0 3.2 0.0 165.9 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 0.3 0.0 0.0 1.2 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 21.5 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 HIF1A "bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8" ENSG00000100644 "Hypoxia inducible factor 1 subunit alpha" Q16665 14 61695513-61748259 "Cancer-related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 448.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 155.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 155.0" "Cell line enhanced" "Detected in many" "LHCN-M2: 941.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000907, HPA001275, CAB017442" Approved Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies" "CAB017442: AB_10621732, HPA000907: AB_2666139, HPA001275: AB_1079057" "unprognostic (1.07e-2)" "unprognostic (1.13e-3)" "unprognostic (9.41e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (2.94e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.77e-2)" "unprognostic (8.39e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (3.58e-1)" "unprognostic (7.35e-2)" "unprognostic (3.88e-2)" 64.9 133.7 22.1 146.6 24.0 448.3 36.2 28.2 26.1 132.9 24.7 42.8 33.6 52.4 74.8 62.1 41.1 145.4 36.5 21.1 28.4 104.2 51.6 75.7 71.4 29.7 29.7 35.3 36.0 91.7 30.7 77.6 33.3 46.9 41.7 35.5 45.3 67.2 12.1 34.2 37.3 59.1 27.2 72.4 37.6 32.4 38.5 55.8 49.5 17.6 88.2 169.9 43.1 26.5 313.6 123.6 112.7 344.7 185.2 297.1 161.5 253.8 270.1 288.7 258.9 54.1 100.3 75.8 186.2 293.0 73.6 71.8 71.0 416.1 352.5 33.7 41.0 46.5 105.3 93.1 414.8 20.1 49.3 523.4 129.2 216.5 225.6 408.6 198.1 44.4 32.3 0.4 941.4 65.6 59.2 24.3 108.9 49.6 159.7 4.3 269.1 22.8 400.2 204.3 100.3 111.9 472.5 67.0 170.7 148.9 70.6 36.3 119.2 700.2 157.3 235.9 215.2 39.1 61.2 84.1 369.9 38.5 194.7 43.8 22.3 155.0 11.5 18.0 14.4 19.5 15.0 13.3 19.6 19.0 22.6 15.6 56.3 19.7 19.4 9.2 11.0 18.4 22.1 24.0 28.2 26.1 21.1 28.4 29.7 29.7 33.3 27.2 38.5 26.5 93.3 70.5 116.0 69.2 157.3 106.4 101.8 102.6 97.9 54.1 38.5 30.1 43.5 87.2 69.0 261.1 50.1 24.8 65.1 44.1 103.7 278.5 3.6 95.6 131.3 152.3 66.4 35.3 45.6 251.6 67.1 81.4 49.5 272.3 223.6 339.7 176.0 30.7 136.4 156.5 39.3 39.0 57.0 145.9 111.7 6.2 24.2 240.2 103.2 53.4 87.1 134.0 26.8 78.9 35.8 236.9 21.9 48.5 60.0 59.3 20.2 192.1 37.7 54.8 52.6 75.8 136.9 80.5 44.2 128.7 87.9 25.4 91.6 92.2 51.8 116.0 HIP1 ILWEQ ENSG00000127946 "Huntingtin interacting protein 1" O00291 7 75533298-75738962 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Transcription, Transcription regulation" "Actin-binding, Activator" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1373.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 9.5;eosinophil: 6.8;neutrophil: 6.8;NK-cell: 3.0;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013606, CAB015334, CAB016402, HPA017964" Enhanced Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB015334: AB_2117565, CAB016402: AB_627725, HPA013606: AB_1850717, HPA017964: AB_1850719" "unprognostic (8.23e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "unprognostic (2.73e-3)" "unprognostic (1.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.02e-2)" "unprognostic (2.70e-2)" "unprognostic (7.98e-2)" "unprognostic (1.73e-3)" "unprognostic (9.67e-2)" "unprognostic (1.75e-1)" "unprognostic (1.00e-2)" "unprognostic (1.09e-1)" 16.7 7.9 23.6 7.3 38.7 5.4 13.2 29.8 29.0 11.7 14.4 6.1 2.7 9.8 9.2 5.3 12.9 8.3 9.0 22.4 24.9 14.8 9.3 18.5 4.7 34.6 35.4 8.0 3.8 4.2 3.4 19.7 32.0 6.8 4.1 4.6 4.0 11.2 4.2 10.6 5.0 12.2 24.5 11.2 4.8 30.4 34.8 3.1 15.3 8.4 4.5 9.0 7.9 50.9 5.2 55.9 37.1 35.2 15.3 20.8 11.1 9.7 6.3 6.2 4.6 3.2 5.0 3.8 11.2 24.2 21.6 6.3 38.1 8.0 8.3 3.1 7.1 3.0 6.6 5.3 15.2 0.8 14.8 16.0 4.8 20.4 4.2 11.4 26.3 4.2 4.0 3.6 10.1 21.6 2.5 22.2 40.5 0.5 6.6 4.4 15.5 0.3 4.7 20.0 1.8 16.2 9.0 5.6 12.5 32.8 34.6 13.9 9.4 18.0 13.7 6.2 13.6 4.0 0.4 8.9 18.1 8.0 12.4 9.5 0.9 6.8 0.9 0.9 0.7 0.3 0.1 0.7 1.4 0.4 0.1 0.5 6.8 3.0 0.7 3.3 1.4 0.3 23.6 38.7 29.8 29.0 22.4 24.9 34.6 35.4 32.0 24.5 34.8 50.9 54.0 60.9 37.5 43.8 7.8 17.6 6.2 7.1 20.5 12.0 14.8 10.7 14.3 11.5 12.2 27.6 12.5 2.1 27.2 2.2 13.7 14.4 256.9 15.5 24.2 54.3 4.8 7.8 16.3 6.0 10.0 17.1 6.1 25.5 14.0 25.9 36.8 22.5 14.9 23.5 19.0 3.0 6.1 18.5 49.1 1373.3 22.4 24.1 10.6 45.9 9.4 14.3 21.6 336.3 313.7 3.1 7.7 24.8 18.4 4.2 0.3 2.6 1.3 9.4 85.5 25.9 44.8 12.1 5.6 5.6 9.1 0.8 13.5 7.7 3.3 3.5 HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.4" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" 18.5 24.0 68.6 10.4 95.5 13.3 22.6 78.8 80.3 16.0 33.5 16.3 31.8 9.0 3.8 18.0 9.0 7.7 18.9 68.0 67.8 50.2 25.6 15.4 17.5 87.3 83.8 5.6 50.2 8.9 42.0 4.7 75.6 21.0 4.9 5.5 58.7 10.5 7.2 51.7 36.0 2.2 65.3 20.9 66.7 8.5 85.7 12.6 21.5 4.4 11.7 11.4 19.7 103.4 38.1 10.8 8.0 33.1 2.3 6.1 39.2 5.9 9.5 5.9 4.6 16.8 11.1 36.0 19.0 4.3 8.9 32.4 9.7 21.4 0.5 5.8 14.0 0.8 13.8 17.8 7.1 2.8 24.5 3.8 14.9 8.0 13.4 8.1 40.5 16.5 9.6 2.0 3.4 54.4 17.4 8.8 7.4 32.8 12.8 9.0 10.2 12.5 19.6 45.4 8.1 17.9 7.1 18.0 9.5 4.3 36.6 1.5 32.8 3.7 27.5 11.7 5.7 24.8 14.2 21.8 6.0 6.0 3.1 0.0 0.0 2.9 2.7 0.0 1.5 9.3 1.7 2.1 0.0 10.6 3.0 1.9 0.2 0.7 0.0 0.0 0.4 2.0 68.6 95.5 78.8 80.3 68.0 67.8 87.3 83.8 75.6 65.3 85.7 103.4 57.0 0.0 13.4 134.5 38.0 13.3 16.8 8.4 6.8 16.4 21.2 18.2 4.2 60.1 11.1 60.7 29.2 3.7 18.2 28.4 0.0 40.1 3.1 21.9 4.7 18.2 7.8 1.3 11.2 28.7 13.1 2.3 80.5 37.5 5.7 25.3 19.2 24.4 0.6 18.5 9.7 29.9 22.4 1.2 4.2 2.9 1.5 2.2 10.6 9.4 0.1 12.5 7.2 168.9 117.8 22.7 25.3 1.2 17.2 20.2 47.5 17.9 14.2 16.6 0.0 2.5 4.1 6.5 13.3 11.5 21.0 1.9 15.0 1.3 23.9 28.4 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74834127-74893359 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 144.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 216.4;Early spermatids: 89.5;Paneth cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 172.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028587, HPA061711" Enhanced Supported Vesicles,Centrosome,Mitochondria,Cytosol NA NA 100000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Mitochondria, Cytosol" "Vesicles, Centrosome" "HPA028587: AB_10602605, HPA061711: " "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 58.2 2.7 2.7 14.6 3.9 45.7 16.0 4.8 5.6 7.8 2.7 46.6 2.8 5.1 66.1 19.9 9.7 9.5 7.9 3.5 3.6 1.9 2.7 15.2 5.8 11.1 6.3 14.9 2.9 2.5 1.9 13.1 8.5 4.9 37.3 144.0 14.7 1.1 45.6 14.6 13.0 3.3 5.9 6.9 18.7 32.8 6.0 3.7 14.1 83.7 7.8 27.1 15.9 8.6 55.9 0.4 12.5 45.4 103.3 10.8 46.5 21.3 30.6 23.4 33.4 44.0 9.8 40.7 20.1 9.9 30.2 19.0 57.0 44.7 67.0 11.6 12.5 55.1 12.4 61.0 32.5 80.8 86.3 18.2 47.3 44.5 77.1 26.3 11.3 23.0 49.2 0.2 6.9 39.6 19.8 82.0 45.3 52.4 38.2 31.8 26.2 31.7 14.2 77.2 9.2 44.6 13.5 67.4 27.4 17.8 3.6 12.8 9.4 74.0 13.4 31.2 39.2 27.1 8.2 20.2 172.5 57.9 19.9 16.8 14.0 51.7 0.2 11.0 0.6 1.2 0.8 0.1 11.8 1.3 1.2 1.2 11.2 0.0 7.7 0.3 1.5 4.7 2.7 3.9 4.8 5.6 3.5 3.6 11.1 6.3 8.5 5.9 6.0 8.6 1.6 16.0 45.3 4.9 5.7 51.6 9.5 26.7 5.7 14.8 16.0 5.6 7.2 4.3 24.2 5.5 83.4 2.3 0.6 216.4 0.0 4.6 89.5 5.8 4.1 4.4 39.0 4.2 0.2 4.5 33.5 6.4 14.8 15.0 22.2 27.2 1.4 0.3 15.8 21.9 0.1 37.7 6.1 20.8 35.1 46.0 14.6 22.8 23.2 25.3 18.9 6.3 2.1 0.5 0.7 25.6 108.3 7.9 4.7 34.3 5.4 0.2 15.2 42.1 13.1 19.9 3.3 3.9 4.2 10.7 57.0 8.2 3.6 5.8 51.7 70.0 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3747.8;Proximal enterocytes: 5267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 1363.9;fHDF/TERT166: 360.3;HBEC3-KT: 366.7;RPMI-8226: 372.1;U-266/70: 344.6" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 635.4 714.2 15.0 34.8 15.5 137.7 566.7 14.7 36.5 504.9 18.0 737.5 278.3 476.1 181.1 366.8 390.3 239.9 473.4 14.6 17.0 687.0 392.0 1007.3 132.0 19.1 15.8 338.8 200.0 18.5 406.5 52.1 16.5 370.9 94.6 9.9 364.1 1.2 246.5 673.3 959.1 14.5 16.8 1413.1 442.2 132.6 18.0 138.9 531.9 14.5 178.3 412.3 466.8 18.3 1363.9 35.0 0.0 0.0 205.9 193.7 1.4 1.4 2.5 2.1 2.3 0.2 0.1 4.0 0.6 360.3 179.1 31.2 0.2 366.7 0.5 3.1 13.5 237.5 9.5 7.4 11.2 0.5 14.4 2.0 0.0 2.5 1.1 0.6 0.2 177.8 0.4 1.4 0.5 0.0 1.1 24.3 2.9 0.2 4.1 27.5 2.5 372.1 246.7 276.5 0.6 12.4 29.3 0.2 11.8 82.8 1.6 30.4 5.8 18.7 0.8 5.8 4.0 344.6 92.6 77.7 0.4 199.9 0.2 321.6 119.0 182.7 164.7 95.5 134.8 96.9 125.4 146.3 18.6 64.3 86.5 119.2 248.7 133.1 109.6 54.6 222.2 191.9 15.0 15.5 14.7 36.5 14.6 17.0 19.1 15.8 16.5 16.8 18.0 18.3 1622.4 371.8 478.6 22.9 1316.2 856.4 886.2 1417.5 228.8 30.8 289.6 188.5 147.4 936.5 952.5 503.9 6.2 18.3 1879.4 2631.8 88.0 3747.8 52.2 239.4 374.0 1717.8 955.2 499.4 3.6 1310.0 18.5 743.5 853.7 556.2 603.0 253.3 1266.2 276.4 1840.9 37.0 19.3 1755.3 1265.4 1575.0 1124.0 95.6 704.6 1419.1 635.0 67.5 3258.0 170.4 3201.9 49.3 16.1 1802.9 2452.4 484.1 1110.7 1026.6 5267.3 294.9 609.6 24.4 558.8 397.3 579.2 197.4 23.8 216.5 947.7 31.7 2234.9 1021.3 1225.4 1262.8 HLA-B AS ENSG00000234745 "Major histocompatibility complex, class I, B" P01889 6 31353872-31357188 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 2493.7" "Cell type enhanced" "Detected in all" "monocytes: 5683.6;NK-cells: 7881.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 638.3;EFO-21: 547.1;U-266/70: 1285.6;U-698: 377.2" CAB015418 Enhanced NA NA 190000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB015418: AB_831547" "unprognostic (2.87e-2)" "unprognostic (1.49e-1)" "unprognostic (4.90e-2)" "unprognostic (2.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.81e-1)" "unprognostic (5.16e-3)" "unprognostic (8.51e-2)" "prognostic favorable (2.90e-4)" "unprognostic (2.69e-3)" "unprognostic (3.05e-2)" "unprognostic (1.59e-1)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (7.83e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-2)" 944.9 581.6 5.5 429.4 8.1 53.5 850.0 5.5 14.4 552.0 6.0 912.0 4.7 567.1 222.1 434.4 488.6 461.2 563.1 4.6 6.7 731.7 488.9 1646.3 1061.9 9.6 10.4 296.9 268.7 24.2 288.3 106.6 7.5 439.2 238.5 8.1 485.9 3.8 237.9 936.4 1295.6 75.4 7.7 2493.7 540.1 132.6 6.7 4.4 593.2 3.8 414.9 476.2 582.0 7.9 638.3 0.0 0.0 0.1 13.5 98.9 3.8 0.5 1.2 0.5 1.1 0.0 1.9 22.7 547.1 111.0 203.2 231.9 116.4 112.4 0.0 2.3 29.9 8.3 0.8 0.0 79.8 0.2 2.4 200.2 0.5 0.0 13.9 183.3 0.4 39.8 1.3 30.2 0.0 0.3 1.5 161.4 0.6 0.0 0.1 19.7 3.4 4.7 163.5 0.6 0.9 3.7 5.5 1.4 1.4 0.2 32.6 6.2 134.7 21.4 4.8 4.9 2.3 1285.6 291.0 377.2 1.1 6.5 0.6 141.1 196.5 232.6 233.0 163.6 215.7 162.4 194.8 198.8 150.8 113.0 150.9 212.0 420.5 179.3 123.6 127.3 213.1 400.2 5.5 8.1 5.5 14.4 4.6 6.7 9.6 10.4 7.5 7.7 6.7 7.9 2836.3 913.5 1007.9 14.0 2936.9 1165.9 761.2 1139.6 396.1 27.7 533.2 550.2 168.5 1382.6 948.3 388.1 6.2 31.4 3876.2 3264.3 68.4 4206.8 63.9 311.6 349.2 2480.7 836.0 550.3 1.4 1771.3 182.3 777.7 1044.4 773.2 620.5 212.5 2189.2 701.5 2602.0 60.6 3.4 2121.8 1129.1 4229.7 2158.6 65.7 644.9 2674.7 891.2 126.5 5683.6 209.2 7881.6 25.1 3.9 2085.3 2327.5 306.9 2983.6 993.4 4541.4 183.9 829.4 27.3 1314.8 356.3 729.7 652.9 91.6 360.3 1004.3 50.9 3661.2 1219.5 1527.4 1161.2 HLA-G ENSG00000204632 "Major histocompatibility complex, class I, G" P17693 6 29826967-29831125 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 13.8;placenta: 11.1" "Cell type enriched" "Detected in many" 45 "Extravillous trophoblasts: 1850.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" CAB016158 Enhanced "Secreted to blood" NA NA 32800000 67000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB016158: AB_627938" "unprognostic (1.13e-2)" "unprognostic (9.95e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (8.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-3)" "unprognostic (2.51e-1)" "prognostic favorable (3.91e-5)" "unprognostic (6.34e-2)" "unprognostic (8.31e-2)" "unprognostic (1.78e-1)" "unprognostic (1.03e-2)" "unprognostic (6.56e-3)" "unprognostic (1.40e-1)" "unprognostic (1.52e-2)" "unprognostic (3.19e-3)" 0.4 0.3 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.0 0.3 0.3 0.1 0.4 0.0 0.0 0.7 0.4 2.7 0.0 0.0 0.0 0.2 1.2 0.0 13.8 11.1 0.0 0.3 0.0 0.0 0.6 0.0 0.2 0.4 0.7 0.0 0.0 1.3 0.7 2.7 0.0 0.4 0.6 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.4 0.8 0.6 1.0 0.7 0.6 0.9 0.4 0.5 0.5 1.3 2.1 0.8 0.6 0.1 1.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.6 0.0 1.2 22.8 7.3 7.1 1.2 0.0 0.2 0.0 0.8 4.3 1.8 0.0 0.0 10.7 2.7 28.1 0.0 4.5 20.1 0.9 1.3 8.8 17.5 2.7 0.0 5.6 1850.2 5.5 1.5 2.6 0.0 0.7 6.4 1.2 25.5 0.0 0.0 34.3 2.0 8.1 27.3 13.0 2.5 4.8 12.4 0.0 1.4 0.0 3.1 0.0 0.0 24.9 19.9 2.6 0.9 14.3 0.2 0.3 0.6 0.0 0.0 4.8 3.8 5.9 2.8 0.1 35.2 40.5 6.8 1.9 18.2 15.0 HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 122.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.7;Excitatory neurons: 77.5;Hepatocytes: 156.8;Horizontal cells: 92.5;Microglial cells: 74.0" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Region enhanced" "Detected in many" "cerebral cortex: 53.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 163.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA068156: AB_2685963, HPA071210: AB_2686361" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "prognostic favorable (1.88e-4)" "unprognostic (5.30e-3)" "prognostic favorable (2.71e-7)" "unprognostic (1.42e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-3)" "unprognostic (2.19e-1)" "prognostic favorable (3.55e-6)" "unprognostic (8.47e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (1.60e-2)" 15.1 21.5 9.8 1.9 23.1 0.4 15.4 0.0 53.3 14.4 0.0 18.0 1.4 14.4 11.0 26.3 12.2 7.8 24.1 17.6 0.0 12.7 122.4 13.4 2.2 0.0 0.6 50.0 2.9 4.0 9.9 1.0 0.0 13.2 3.4 43.2 24.1 12.4 7.7 16.7 4.3 12.3 0.0 8.2 6.1 4.1 3.9 3.4 34.3 9.9 7.7 12.3 7.8 17.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.9 0.5 0.0 0.0 0.0 0.4 0.2 0.0 27.3 0.7 0.0 0.1 163.0 0.1 0.9 0.2 0.1 0.7 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.6 1.1 0.0 0.1 0.0 2.4 0.0 0.4 0.4 13.0 0.1 11.1 0.6 0.0 7.2 0.2 0.0 0.2 0.0 0.1 0.8 0.2 0.6 0.5 5.1 4.9 0.0 0.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 23.1 0.0 53.3 17.6 0.0 0.0 0.6 0.0 0.0 3.9 17.2 13.8 3.2 42.8 22.2 0.4 22.3 4.4 1.4 56.9 120.7 5.9 16.4 38.6 12.8 6.3 7.3 10.4 0.1 0.5 0.0 11.7 1.9 1.3 0.1 6.2 19.7 3.0 0.8 77.5 0.9 0.0 17.6 0.0 0.6 0.0 0.5 6.1 156.8 0.1 92.5 36.6 0.6 0.0 3.5 4.0 4.7 28.3 0.7 10.6 74.0 0.1 60.7 0.0 24.6 6.9 0.4 0.0 39.1 1.5 1.3 2.8 23.3 1.0 15.0 13.1 4.5 7.4 0.4 5.0 33.7 27.6 1.2 3.8 0.5 0.4 0.4 HMGA1 HMGIY ENSG00000137309 "High mobility group AT-hook 1" P17096 6 34236873-34246231 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 275.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 947.5;Cytotrophoblasts: 894.3;Pancreatic endocrine cells: 1838.5;Prostatic glandular cells: 1483.3;Syncytiotrophoblasts: 822.8;Urothelial cells: 1681.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032200, HPA065612, HPA068442" Enhanced Supported Nucleoplasm,Nucleoli NA NA 72000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Nucleoli "CAB032200: AB_2117771, HPA065612: , HPA068442: " "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (3.36e-4)" "unprognostic (8.54e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.55e-1)" "unprognostic (8.22e-2)" "unprognostic (4.52e-3)" "unprognostic (1.19e-1)" "unprognostic (4.37e-1)" "unprognostic (2.65e-2)" 28.1 9.0 22.1 79.6 20.9 184.0 27.4 17.8 27.3 93.3 2.6 59.9 118.7 22.8 16.7 275.1 41.0 39.2 35.8 24.1 23.3 89.2 20.0 46.5 139.3 24.3 19.1 4.7 31.9 15.0 15.4 82.4 21.1 27.7 57.2 32.2 69.7 12.6 119.7 141.6 103.6 9.7 15.4 68.7 73.3 80.1 22.9 156.0 31.5 35.1 154.7 100.1 109.6 25.2 1418.7 547.0 274.2 192.9 124.8 916.6 1193.8 556.0 628.8 421.5 233.4 361.3 960.0 658.9 273.1 229.1 264.0 294.7 326.2 991.8 332.3 146.0 228.2 202.6 177.1 488.2 263.7 732.1 227.3 396.1 109.4 765.1 395.8 1083.8 1290.0 369.3 832.0 32.9 596.0 143.0 650.0 898.8 1340.9 697.5 950.3 947.6 6.2 728.0 286.6 128.4 477.0 202.5 59.3 278.3 533.3 430.2 112.2 775.8 1132.1 218.5 691.2 321.3 528.0 260.5 444.5 867.4 461.2 301.7 1115.0 18.7 26.6 35.5 24.4 26.8 32.2 63.5 45.0 39.0 79.6 39.5 52.0 42.9 6.7 20.1 26.5 86.6 55.8 30.7 22.1 20.9 17.8 27.3 24.1 23.3 24.3 19.1 21.1 15.4 22.9 25.2 11.0 28.9 21.7 2.3 117.8 432.3 947.5 181.3 109.8 29.0 88.8 47.4 30.8 28.6 106.1 40.5 4.2 894.3 70.3 173.5 46.9 755.3 7.2 50.5 14.6 113.9 117.0 268.3 5.4 277.5 799.8 72.0 79.5 115.3 66.7 8.3 18.2 12.3 377.2 11.8 5.7 226.4 97.6 74.0 149.9 24.5 5.6 94.3 90.7 1.0 74.3 44.1 33.0 4.5 2.7 1838.5 249.1 2.6 198.2 1483.3 174.5 15.8 21.7 41.9 0.0 18.6 77.7 40.2 417.6 224.7 361.4 822.8 66.6 0.9 364.3 1681.0 HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9;testis: 3.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 16.0;Early spermatids: 18.4;Glandular and luminal cells: 17.3;Granulosa cells: 29.7;Pancreatic endocrine cells: 19.9;Smooth muscle cells: 33.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 324.4;hTERT-RPE1: 232.6;SuSa: 216.1" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: AB_2676335" "unprognostic (2.39e-1)" "unprognostic (6.00e-2)" "unprognostic (2.08e-1)" "unprognostic (3.68e-3)" "unprognostic (5.21e-3)" "prognostic unfavorable (4.79e-4)" "unprognostic (4.05e-3)" "unprognostic (6.17e-3)" "unprognostic (6.71e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-6)" "unprognostic (3.33e-2)" "unprognostic (4.55e-5)" "unprognostic (4.22e-2)" "unprognostic (2.53e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (2.86e-4)" 0.4 0.0 0.3 0.3 0.2 4.9 0.2 0.7 0.5 1.1 0.0 2.1 1.3 0.4 0.0 0.3 1.2 0.3 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.6 0.9 0.0 0.4 0.2 0.2 0.0 2.4 0.5 0.1 0.1 1.5 0.4 1.0 0.1 0.1 0.1 1.1 3.8 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.4 47.9 21.4 324.4 45.8 15.0 82.0 0.1 148.5 68.5 26.0 25.8 28.1 19.8 0.0 92.3 7.0 120.0 20.5 54.2 129.3 123.8 0.2 56.2 0.2 0.7 169.3 8.4 4.7 0.4 62.7 8.0 55.2 98.4 232.6 105.0 0.2 0.1 0.6 149.9 0.2 0.4 27.8 190.3 4.6 89.2 12.7 16.1 0.1 68.9 0.3 0.0 0.0 0.1 0.1 85.0 216.1 0.5 0.7 120.8 89.5 26.9 71.2 45.3 0.2 0.2 0.4 112.0 0.3 21.4 1.4 0.2 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.3 0.6 0.1 0.0 0.0 0.3 0.2 0.7 0.5 0.2 0.1 0.4 0.2 0.2 0.1 0.2 0.4 0.0 0.0 1.1 5.9 0.2 0.0 3.6 16.0 2.8 0.0 0.1 0.1 1.7 0.0 3.0 0.0 0.0 0.8 0.0 5.0 0.0 2.5 18.4 10.4 0.8 0.6 0.0 7.4 0.8 0.8 0.5 2.3 3.1 17.3 0.0 29.7 0.7 0.0 9.0 0.0 0.9 5.1 4.1 0.0 0.0 9.0 0.3 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.9 19.9 4.5 0.0 0.4 5.5 4.0 0.3 7.3 0.0 0.0 1.1 33.7 13.5 0.6 0.3 0.1 0.8 0.3 0.3 8.4 1.1 HMGXB4 "HMG2L1, THC211630" ENSG00000100281 "HMG-box containing 4" Q9UGU5 22 35257452-35295807 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000725, HPA076681" Approved Approved Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA000725: AB_1079073, HPA076681: " "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "prognostic favorable (3.24e-5)" "unprognostic (4.81e-2)" "unprognostic (1.93e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.79e-4)" "unprognostic (2.85e-2)" "unprognostic (8.25e-3)" "unprognostic (6.67e-3)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.62e-1)" "unprognostic (8.71e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.20e-1)" "unprognostic (8.54e-2)" 7.9 4.7 5.1 7.8 6.5 23.4 8.1 6.5 7.2 6.7 3.7 6.6 6.4 11.6 3.7 8.6 7.6 7.0 6.5 5.3 5.8 4.1 5.1 5.6 7.5 5.9 5.3 14.0 7.0 8.2 2.2 9.0 5.8 7.4 7.4 8.5 6.7 6.2 7.2 6.7 6.7 9.5 4.9 6.3 5.0 7.9 6.1 11.3 6.7 7.2 7.7 8.6 5.3 8.2 22.6 4.9 37.6 17.6 9.3 16.4 9.9 22.3 31.6 22.1 20.1 4.3 8.9 27.5 10.2 23.3 13.4 13.0 14.9 18.3 26.2 23.3 18.6 24.6 6.5 5.3 11.2 56.8 25.1 15.8 14.0 18.5 14.2 13.3 16.8 21.0 19.7 21.6 17.1 11.0 35.1 15.1 15.7 15.6 14.2 25.3 32.5 10.7 13.8 17.5 22.1 23.0 19.6 15.6 16.5 10.6 9.6 16.1 13.3 20.1 41.9 24.1 19.5 26.1 25.5 34.8 17.1 15.9 31.7 34.5 12.5 16.9 13.4 14.8 11.7 10.4 13.1 14.3 9.8 13.3 8.4 9.6 19.0 9.6 13.8 10.8 12.1 5.9 5.1 6.5 6.5 7.2 5.3 5.8 5.9 5.3 5.8 4.9 6.1 8.2 30.6 12.8 18.5 18.3 30.9 20.9 52.3 33.3 16.5 60.6 26.0 25.1 14.4 34.3 29.7 27.6 35.5 48.0 30.1 31.5 29.4 40.4 14.7 22.2 35.5 32.4 16.9 56.6 17.7 29.3 54.5 34.8 27.5 31.9 52.1 51.9 36.8 24.1 31.8 67.3 20.5 31.9 28.5 26.4 17.6 12.7 53.7 29.1 8.8 7.5 32.1 21.0 34.0 17.1 31.5 35.3 27.4 56.8 21.2 58.1 26.4 21.0 15.6 73.5 39.5 46.4 32.9 67.0 82.9 28.0 22.6 64.7 30.4 33.1 32.3 57.8 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 HNF1A "HNF1, LFB1, MODY3, TCF1" ENSG00000135100 "HNF1 homeobox A" 12 120978543-121002512 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 15.4;kidney: 16.7;liver: 34.7;pancreas: 9.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 14.5;Hepatocytes: 15.8;Intestinal goblet cells: 9.4;Paneth cells: 14.8;Proximal enterocytes: 33.4;Proximal tubular cells: 16.0;Undifferentiated cells: 10.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 4.5;liver cancer: 3.6;pancreatic cancer: 1.4;renal cancer: 3.6;stomach cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 8.9;CACO-2: 29.4;Hep G2: 32.5;OE19: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010430, HPA035231" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "CAB010430: AB_2116746, HPA035231: AB_2674528" "unprognostic (5.92e-3)" "unprognostic (8.47e-2)" "unprognostic (4.12e-3)" "unprognostic (6.18e-3)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (9.18e-2)" "unprognostic (9.18e-2)" "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" "unprognostic (9.77e-3)" "unprognostic (5.21e-2)" "unprognostic (6.25e-3)" "unprognostic (5.55e-2)" "unprognostic (2.48e-1)" "unprognostic (6.93e-3)" 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.2 0.0 5.5 15.4 0.2 0.0 0.1 1.1 0.8 0.0 0.1 0.1 16.7 34.7 0.0 0.0 0.1 0.1 0.0 9.5 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.2 14.3 0.1 0.0 0.0 4.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.6 0.2 0.0 1.2 4.3 0.0 1.8 0.0 0.1 0.4 14.5 0.0 2.6 0.0 1.3 0.2 0.3 4.8 0.0 0.2 5.3 0.1 0.2 4.6 0.5 0.0 0.1 0.4 15.8 0.1 0.0 0.2 9.4 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.7 0.5 0.0 0.5 0.0 3.9 14.8 0.0 0.1 0.5 33.4 16.0 0.0 0.3 0.0 0.8 0.3 0.1 0.3 0.0 0.3 0.0 0.5 0.0 10.8 0.4 HNRNPA2B1 HNRPA2B1 ENSG00000122566 "Heterogeneous nuclear ribonucleoprotein A2/B1" P22626 7 26171151-26201529 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transport" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, CAB012403, HPA065537" Supported Enhanced Nucleoplasm "Intracellular and membrane" NA NA 11000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB012403: , HPA001666: AB_1850836, HPA005812: AB_2667441, HPA065537: AB_2685507" "unprognostic (1.19e-1)" "unprognostic (4.45e-1)" "unprognostic (2.33e-1)" "unprognostic (6.39e-2)" "unprognostic (5.64e-2)" "unprognostic (8.04e-3)" "prognostic unfavorable (1.03e-6)" "unprognostic (1.25e-2)" "unprognostic (9.12e-3)" "unprognostic (4.35e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (5.12e-4)" "prognostic unfavorable (8.01e-5)" "unprognostic (6.74e-2)" "unprognostic (3.36e-2)" "unprognostic (2.02e-1)" "unprognostic (1.56e-2)" 367.0 421.3 101.3 151.4 105.4 77.6 314.1 110.9 140.3 403.5 106.4 381.8 124.8 404.3 116.1 417.6 376.3 62.4 463.6 99.7 106.4 530.8 388.5 364.9 184.1 106.4 105.0 527.8 350.2 80.8 337.6 118.9 108.2 300.8 127.5 131.1 325.1 79.2 764.9 280.5 419.0 84.2 102.3 447.5 353.4 370.5 105.4 174.8 367.2 92.0 172.5 339.9 360.8 111.7 202.5 101.8 491.6 312.7 110.7 117.5 249.6 255.8 110.7 149.6 183.6 159.8 338.5 210.2 104.2 180.1 218.8 300.0 196.3 268.7 288.5 74.9 191.2 232.6 309.9 212.1 72.9 374.6 359.4 123.6 192.4 156.3 253.3 194.6 161.1 273.9 210.9 250.4 280.4 229.1 216.5 817.2 320.7 81.7 117.7 239.5 122.1 159.3 287.0 335.8 190.7 245.6 203.5 291.8 127.7 393.6 326.3 359.7 222.0 193.2 265.6 184.6 253.7 367.0 296.0 308.7 149.9 453.8 316.5 0.0 1.7 1.3 4.8 1.0 4.0 2.7 3.0 0.8 0.8 0.8 2.7 2.6 0.6 3.3 0.8 1.6 1.0 0.5 101.3 105.4 110.9 140.3 99.7 106.4 106.4 105.0 108.2 102.3 105.4 111.7 717.8 487.2 591.0 194.6 667.5 738.5 797.7 793.2 560.5 469.4 361.0 361.3 702.1 316.0 665.8 343.9 298.2 971.6 707.7 435.1 461.8 568.0 128.2 465.8 640.8 600.5 491.4 683.2 123.3 452.2 939.9 602.7 449.6 591.1 644.7 680.5 333.4 382.8 613.1 312.9 147.2 533.1 496.4 388.5 681.9 150.0 411.0 640.3 393.1 157.4 572.0 545.4 484.1 198.0 320.6 438.2 438.7 390.0 751.0 520.4 428.4 506.8 608.0 547.0 440.4 599.4 726.5 596.9 490.6 573.8 600.5 1082.8 701.7 652.2 541.4 632.1 HOOK3 HK3 ENSG00000168172 "Hook microtubule tethering protein 3" Q86VS8 8 42896946-43030535 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024756 Approved Supported "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA024756: AB_1850913" "unprognostic (1.84e-2)" "unprognostic (1.61e-1)" "unprognostic (2.73e-1)" "unprognostic (8.61e-3)" "unprognostic (6.05e-2)" "unprognostic (1.77e-3)" "unprognostic (2.36e-1)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.63e-1)" "unprognostic (3.78e-1)" "unprognostic (2.55e-1)" "unprognostic (7.12e-2)" 9.8 6.2 3.1 7.4 8.7 11.1 8.9 11.9 8.9 8.2 1.5 7.5 7.5 8.3 8.2 10.6 7.0 14.4 4.6 4.0 11.1 6.6 7.3 8.0 6.6 7.6 4.9 6.1 7.6 7.2 4.1 8.6 7.3 12.4 7.7 8.8 9.6 7.1 10.6 8.1 8.9 6.7 4.4 6.6 9.5 11.4 4.9 6.4 21.7 8.2 7.4 9.3 6.0 15.5 11.2 10.9 26.2 14.2 19.0 16.7 10.1 14.0 11.6 11.5 10.7 14.5 12.8 13.9 13.9 18.8 10.9 6.4 22.1 9.5 18.5 9.5 6.4 26.3 9.2 10.2 10.6 2.8 14.9 13.7 6.6 15.4 13.2 15.9 16.7 9.7 14.7 15.9 14.0 2.7 21.7 5.2 9.5 8.8 3.3 12.6 27.3 3.5 8.6 16.5 6.7 10.6 15.9 6.7 7.4 11.4 12.2 9.4 30.2 17.1 13.2 20.9 9.0 15.6 18.6 18.1 14.5 9.9 25.8 9.4 2.0 2.0 1.2 2.0 0.4 0.9 1.1 0.9 2.4 0.9 0.6 0.8 2.2 1.2 1.9 1.4 0.8 1.1 3.1 8.7 11.9 8.9 4.0 11.1 7.6 4.9 7.3 4.4 4.9 15.5 75.3 93.0 60.6 90.1 43.2 68.3 36.2 28.7 43.3 40.1 29.4 22.4 48.2 44.3 43.6 25.8 33.3 43.6 40.6 26.1 27.4 47.1 120.3 60.0 84.0 65.2 65.4 34.5 102.1 32.8 25.9 65.8 33.1 93.8 53.8 37.9 60.3 36.4 38.0 75.7 107.6 26.9 20.3 79.4 96.4 36.3 44.7 82.8 55.2 78.7 118.6 36.3 37.0 119.1 157.8 59.7 27.6 53.8 43.6 43.5 37.3 21.4 35.2 32.2 65.7 63.4 74.6 28.0 21.5 39.8 74.7 113.7 40.9 42.6 16.2 71.1 HOXA11 "HOX1, HOX1I" ENSG00000005073 "Homeobox A11" P31270 7 27181157-27185232 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 44.8;endometrium 1: 96.7;smooth muscle: 41.2" "Cell type enriched" "Detected in some" 19 "Endometrial stromal cells: 116.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.5;HEK 293: 44.0;THP-1: 34.7;U-937: 43.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 36 "spinal cord: 3.5" "HPA006770, HPA035623" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "HPA006770: AB_2667672, HPA035623: AB_10601576" "unprognostic (5.95e-2)" "unprognostic (9.23e-2)" "unprognostic (3.07e-2)" "unprognostic (2.70e-2)" "unprognostic (6.29e-2)" "unprognostic (9.78e-2)" "unprognostic (2.82e-3)" "unprognostic (4.36e-2)" "unprognostic (1.61e-2)" "unprognostic (3.05e-2)" "unprognostic (2.08e-3)" "unprognostic (1.73e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (2.17e-2)" "unprognostic (6.90e-2)" "unprognostic (2.03e-2)" "unprognostic (2.56e-1)" 3.5 0.7 0.0 1.4 0.0 0.0 0.4 0.0 0.0 44.8 0.0 23.1 0.0 96.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 10.0 0.0 14.7 3.9 0.0 0.1 9.6 7.9 1.5 0.2 41.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 17.0 10.4 0.0 4.8 0.3 0.0 13.1 15.2 11.1 0.0 26.8 32.5 18.9 13.8 0.3 1.7 0.0 6.1 23.5 0.1 3.2 16.3 0.0 14.7 1.6 44.0 5.7 11.2 0.7 0.9 12.5 1.7 6.5 0.6 0.1 0.0 0.0 14.1 1.1 0.4 0.0 2.2 0.4 0.0 9.4 0.0 4.4 13.1 0.7 0.0 0.3 9.6 8.1 5.6 0.0 6.7 0.0 2.0 3.6 1.2 34.7 0.0 0.2 12.9 3.2 1.5 0.0 0.0 0.0 0.2 43.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.8 0.0 0.1 0.3 1.1 5.9 0.0 0.8 4.0 116.8 1.3 5.3 0.0 0.0 0.0 0.1 3.6 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 2.8 0.2 0.2 0.0 0.0 0.0 0.9 5.8 1.2 0.1 0.0 0.0 0.0 0.6 0.1 1.1 1.3 HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 23.1;placenta: 17.1;prostate: 22.3;seminal vesicle: 23.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 41.3" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 26.9;HEK 293: 37.3;PC-3: 18.4;RT4: 42.1;THP-1: 18.2;U-937: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: AB_2679536, HPA069061: " "unprognostic (7.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-2)" "unprognostic (9.22e-3)" "unprognostic (7.30e-3)" "unprognostic (8.39e-3)" "unprognostic (1.54e-1)" "unprognostic (1.42e-11)" "unprognostic (2.58e-3)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (1.36e-2)" 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.1 0.0 9.9 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 22.3 11.9 0.0 0.0 23.3 2.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.1 14.1 0.0 2.2 1.6 0.0 2.5 0.2 0.0 0.1 13.2 14.4 5.1 3.3 2.8 0.2 0.0 1.6 6.2 0.7 0.0 26.9 0.0 4.3 0.0 37.3 1.9 6.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 8.7 0.0 11.8 18.4 2.7 0.6 0.0 0.1 42.1 0.7 0.0 3.3 0.0 0.3 2.0 0.0 18.2 0.0 0.5 4.5 0.3 0.1 0.0 0.0 0.0 0.0 20.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.0 0.0 0.6 0.1 4.0 1.1 8.4 0.0 0.0 0.0 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.1 2.8 0.5 0.0 0.0 0.1 0.1 0.1 0.0 10.3 3.1 HOXA5 "HOX1, HOX1C" ENSG00000106004 "Homeobox A5" P20719 7 27141052-27143681 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 80.9;epididymis: 49.0;fallopian tube: 49.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 99.6;Breast myoepithelial cells: 27.2;Proximal tubular cells: 27.1;Squamous epithelial cells: 46.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 51 "medulla oblongata: 38.3;pons: 10.5;spinal cord: 24.6;white matter: 16.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 94.2;HEK 293: 160.4;RPTEC TERT1: 36.2" "Region enriched" "Detected in single" 220 "pons and medulla: 22.0" "Group enriched" "Detected in some" 33 "medulla oblongata: 4.4;spinal cord: 16.3" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (2.43e-1)" "unprognostic (3.98e-3)" "unprognostic (2.99e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.87e-1)" "unprognostic (7.80e-2)" "unprognostic (4.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.02e-2)" "unprognostic (5.54e-2)" "unprognostic (2.31e-1)" "unprognostic (5.47e-2)" "unprognostic (3.00e-2)" "unprognostic (4.37e-2)" "unprognostic (3.26e-2)" "unprognostic (3.47e-3)" "unprognostic (2.00e-1)" 16.8 80.9 0.2 3.0 0.1 3.1 11.6 0.2 0.4 7.1 0.0 18.7 2.7 12.3 49.0 5.2 49.4 0.9 0.2 0.1 0.1 25.5 0.8 19.9 1.8 38.3 0.4 2.9 1.4 3.3 0.0 0.2 10.5 8.6 6.9 0.0 0.0 9.8 6.7 7.8 13.7 6.2 24.6 3.3 11.7 0.6 0.0 0.5 1.1 0.3 0.1 11.8 4.6 16.6 5.7 2.8 0.0 94.2 0.1 0.0 0.4 1.6 1.2 1.7 1.5 1.7 9.7 3.1 13.5 3.0 2.0 7.6 5.3 0.4 1.7 1.4 160.4 2.2 1.2 5.7 0.9 3.6 2.5 10.3 0.5 3.1 5.4 0.0 20.8 5.5 0.4 0.0 3.2 1.7 0.0 1.1 0.0 2.1 2.9 13.4 0.4 0.0 36.2 7.6 10.9 0.1 7.2 0.0 3.6 0.3 1.1 1.3 8.3 0.3 1.2 5.6 3.9 0.0 0.1 3.3 0.7 10.8 10.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.6 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.1 0.1 38.3 0.4 10.5 24.6 0.0 16.6 9.3 0.0 1.1 0.0 0.9 3.4 6.4 0.1 99.6 0.0 17.3 27.2 8.0 0.0 0.0 0.0 0.0 0.0 2.8 17.0 7.9 0.1 0.0 0.9 19.7 8.4 9.0 2.5 0.0 0.0 0.0 11.5 2.6 0.4 0.0 0.0 21.0 0.0 0.6 0.0 0.0 10.8 0.0 2.5 1.5 0.3 0.3 9.2 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 15.5 0.0 1.0 2.2 9.6 27.1 0.1 0.0 0.0 4.5 14.3 0.9 0.7 46.7 2.8 0.1 1.7 0.2 18.8 6.3 HOXA9 "HOX1, HOX1G" ENSG00000078399 "Homeobox A9" P31269 7 27162438-27175180 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4;skin 1: 25.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Endometrial stromal cells: 31.1;Enteroendocrine cells: 39.4;Proximal tubular cells: 75.1;Suprabasal keratinocytes: 27.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 6.7;myeloid DC: 5.6;NK-cell: 11.5" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;granulocytes: 6.7;NK-cells: 11.5" "Cell line enhanced" "Detected in many" "HEK 293: 124.4;PC-3: 43.9;RPTEC TERT1: 42.0;SCLC-21H: 113.4;U-937: 42.3" "Not detected" "Not detected" "HPA061982, HPA076200" Uncertain Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA061982: AB_2684651, HPA076200: " "unprognostic (4.72e-1)" "unprognostic (1.23e-2)" "unprognostic (2.86e-1)" "unprognostic (5.24e-3)" "unprognostic (2.36e-1)" "unprognostic (2.02e-1)" "unprognostic (8.35e-2)" "unprognostic (8.44e-3)" "unprognostic (5.50e-2)" "unprognostic (5.71e-2)" "unprognostic (9.87e-3)" "unprognostic (4.42e-2)" "unprognostic (2.80e-3)" "unprognostic (6.45e-2)" "unprognostic (7.58e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" 4.7 5.9 0.0 2.8 0.0 2.5 6.9 0.0 0.2 12.7 0.0 22.0 0.0 17.0 5.6 1.0 19.6 0.0 0.0 0.0 0.0 28.4 0.0 0.4 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.8 0.1 14.1 3.9 0.0 0.0 4.5 16.1 25.7 14.8 1.9 0.2 0.9 0.2 0.0 0.0 1.9 0.1 0.0 0.0 16.8 13.8 0.2 37.7 0.0 0.0 18.4 6.0 4.4 0.0 14.6 11.7 1.2 1.2 2.4 1.4 0.3 1.4 7.9 0.0 34.7 23.5 0.0 1.2 0.0 124.4 0.3 1.1 0.0 0.6 0.0 0.5 6.0 0.0 0.0 0.0 0.0 30.6 0.0 0.0 0.0 1.2 0.0 0.0 1.2 0.0 0.0 43.9 8.1 0.0 0.0 42.0 0.7 113.4 0.0 15.6 0.0 0.3 0.6 0.0 31.3 1.4 0.0 11.4 14.0 0.2 0.0 0.0 0.0 0.0 42.3 0.0 6.7 0.8 0.0 1.3 0.2 0.2 0.1 0.0 0.1 5.6 0.9 0.2 0.0 0.8 11.5 0.3 1.8 0.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 6.2 0.0 0.0 0.0 2.0 25.1 14.9 0.0 3.4 0.0 12.2 14.7 0.5 0.0 0.0 18.4 0.0 0.2 2.9 10.5 54.8 0.0 0.0 1.0 31.1 4.3 39.4 16.6 0.0 0.0 0.3 4.8 0.0 0.6 0.0 0.0 0.7 0.0 0.3 0.0 0.0 21.7 0.0 3.4 4.2 0.0 0.0 1.9 5.4 0.0 0.8 0.0 2.1 0.0 0.0 0.0 20.2 0.0 0.9 19.4 13.3 75.1 0.0 0.0 0.0 3.0 4.6 0.0 1.0 2.6 27.6 0.3 2.2 0.3 21.4 14.2 HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 5.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Distal tubular cells: 1.9;Melanocytes: 3.6;Proximal enterocytes: 3.7;Spermatocytes: 3.5;Suprabasal keratinocytes: 3.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 34.7;BJ hTERT+: 17.5;HaCaT: 15.4;HeLa: 12.4;T-47d: 27.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 1.3" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 1.8 5.0 1.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 9.3 1.1 0.0 34.7 3.2 4.9 0.0 5.1 17.5 7.4 5.3 0.3 1.3 0.0 0.3 4.8 0.0 15.4 6.6 0.0 3.3 1.0 0.1 0.2 12.4 0.0 0.0 0.1 0.1 0.9 1.4 0.0 0.4 0.0 0.0 0.3 1.5 0.0 4.8 2.2 0.0 0.1 0.0 10.1 0.1 0.0 0.6 0.0 0.7 1.2 0.0 0.2 3.2 7.8 3.1 0.3 27.4 0.0 0.0 0.0 5.8 0.4 0.3 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.7 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.9 0.0 0.0 0.0 1.0 1.0 3.5 0.9 0.0 3.8 0.0 0.1 0.0 0.2 0.0 HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Breast myoepithelial cells: 3.0;Spermatogonia: 1.2;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 31.2;HaCaT: 66.1;SK-BR-3: 36.0;T-47d: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA051634 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.7 10.5 0.0 31.2 0.5 0.0 18.4 1.9 4.4 2.8 1.5 2.7 0.5 0.0 0.4 0.0 2.0 66.1 8.0 2.1 1.6 0.0 6.4 0.0 8.4 0.0 0.0 0.0 6.6 0.0 15.4 0.0 6.0 0.0 0.0 0.1 11.8 0.0 11.5 20.1 0.0 0.0 0.3 6.6 2.7 0.0 0.4 0.0 0.0 6.0 0.0 0.0 10.4 36.0 4.9 7.4 28.1 0.1 0.0 0.1 13.1 0.2 4.2 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.7 3.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 2.4 0.1 0.0 0.0 0.0 0.0 HOXD11 "HOX4, HOX4F" ENSG00000128713 "Homeobox D11" P31277 2 176104216-176109754 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.1;intestine: 3.8;kidney: 4.7;prostate: 3.3;vagina: 4.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 26.7;Collecting duct cells: 22.0;Distal enterocytes: 22.8;Endometrial stromal cells: 29.0;Enteroendocrine cells: 20.6;Urothelial cells: 14.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 21.9;RPTEC TERT1: 2.6;SCLC-21H: 6.1;U-251 MG: 4.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 40 "spinal cord: 3.9" HPA055155 Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA055155: AB_2682719" "unprognostic (1.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.05e-2)" "unprognostic (1.85e-3)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (2.13e-2)" "unprognostic (6.73e-2)" "unprognostic (5.00e-2)" "unprognostic (2.11e-8)" "unprognostic (2.09e-3)" "unprognostic (2.49e-2)" "unprognostic (2.27e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 3.8 0.0 7.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.0 0.0 0.9 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 1.4 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 6.1 0.3 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.4 26.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.0 0.0 0.1 0.0 22.8 9.8 0.0 0.0 1.1 29.0 1.7 20.6 0.0 0.0 0.0 0.1 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 8.6 0.0 0.0 1.2 0.2 0.9 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.8 1.2 0.0 8.8 0.0 0.3 0.0 0.0 0.0 0.1 2.3 0.1 0.4 0.0 0.9 0.0 0.1 0.0 9.2 14.0 HOXD13 "HOX4I, SPD" ENSG00000128714 "Homeobox D13" P35453 2 176092721-176095944 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "cervix: 14.2;intestine: 18.2;prostate: 9.7;seminal vesicle: 16.3;vagina: 17.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 12.4;Distal enterocytes: 5.5;Enteroendocrine cells: 29.0;Intestinal goblet cells: 9.1;Paneth cells: 5.5;Prostatic glandular cells: 6.3;Undifferentiated cells: 9.9;Urothelial cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.4;HEK 293: 53.3;HL-60: 61.7;JURKAT: 16.7;NB-4: 36.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064064 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA064064: AB_2685186" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (2.52e-3)" "unprognostic (7.25e-2)" "unprognostic (2.08e-2)" "unprognostic (4.62e-2)" "unprognostic (1.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.82e-4)" "unprognostic (4.95e-2)" "unprognostic (3.70e-2)" "unprognostic (9.98e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.2 0.0 18.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 9.7 7.6 0.0 0.0 16.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 2.2 4.7 0.0 0.0 0.0 0.0 0.0 5.1 0.0 18.4 0.0 2.8 0.0 53.3 8.3 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 3.9 0.0 0.0 0.0 0.0 36.3 1.9 0.0 3.0 0.0 0.2 0.0 0.0 0.4 15.2 3.7 3.8 0.0 8.9 0.2 0.0 0.0 0.0 1.8 0.0 0.8 5.1 0.0 0.0 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.9 0.0 0.1 0.1 29.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.4 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 9.9 6.7 HP ENSG00000257017 Haptoglobin P00738 16 72054505-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "liver: 61113.6" "Cell type enriched" "Detected in many" 43 "Hepatocytes: 59512.7" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Region enhanced" "Detected in all" "medulla oblongata: 29.7" "Group enriched" "Detected in many" 5 "classical monocyte: 49.3;eosinophil: 80.2" "Group enriched" "Detected in many" 7 "granulocytes: 80.2;monocytes: 49.3" "Group enriched" "Detected in some" 5 "Hep G2: 232.2;HSkMC: 121.4" "CAB003787, HPA047750, HPA066795" Enhanced Approved Vesicles "Secreted to blood" NA NA 998000000000 100000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB003787: , HPA047750: AB_2680146, HPA066795: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavorable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" 673.1 11.4 1.3 26.9 1.7 231.5 34.2 1.4 2.9 71.9 3.6 3.6 1.5 3.5 2.9 5.3 74.6 1.3 146.7 1.4 1.4 19.8 61113.6 91.3 1.7 29.7 2.0 9.9 7.6 0.2 49.9 2.5 3.7 7.3 0.6 0.7 6.1 0.2 5.0 3.4 4.4 4.5 2.3 72.0 6.2 2.1 8.3 2.7 6.3 0.4 3.0 3.8 3.3 5.9 0.0 0.0 0.0 0.0 6.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 8.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 11.2 0.2 232.2 0.3 33.3 6.2 121.4 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 2.0 0.4 2.6 0.0 0.0 1.1 23.6 0.0 0.0 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 6.8 5.1 0.0 0.8 0.0 0.0 3.9 0.0 14.1 0.0 12.7 0.0 6.2 49.3 80.2 0.0 2.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 14.2 0.0 2.1 0.0 0.0 15.2 1.3 1.7 1.4 2.9 1.4 1.4 29.7 2.0 3.7 2.3 8.3 5.9 0.4 19.2 228.7 1.6 96.1 0.1 0.7 1.9 0.0 0.4 0.4 0.3 66.6 1085.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 56.7 0.0 1128.3 0.0 10.4 0.1 45.5 0.0 1.3 3.8 0.4 1038.7 59512.7 2.3 0.0 0.0 0.2 4.1 1381.4 0.0 0.5 10.2 7.8 1.8 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 1.5 7.5 0.2 0.0 2.6 1.8 0.0 0.0 0.1 0.3 0.1 90.3 0.0 0.3 0.1 HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 235.0;urinary bladder: 376.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 457.8;Extravillous trophoblasts: 701.7;granulocytes: 864.5;Proximal enterocytes: 500.6;Urothelial cells: 922.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 123.7;T-reg: 45.0" "Group enriched" "Detected in many" 73 "granulocytes: 123.7;T-cells: 45.0" "Cell line enhanced" "Detected in many" "A549: 157.8;ASC diff: 110.6;HEL: 355.0;OE19: 102.1;RT4: 565.7;SuSa: 121.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" 9.2 16.5 1.0 11.4 0.7 2.7 159.9 0.5 1.2 32.2 8.7 60.9 152.2 45.5 36.5 81.6 13.4 24.9 1.6 1.2 2.8 60.2 210.8 91.0 5.5 1.4 2.0 1.1 2.6 85.3 2.1 99.1 1.0 10.2 57.4 1.0 7.7 4.0 2.5 39.8 117.3 63.7 0.8 10.3 235.0 1.6 2.2 12.2 1.7 3.0 26.6 376.0 83.0 0.7 0.0 157.8 0.0 0.0 110.6 5.4 0.4 0.0 0.0 0.0 0.4 45.1 0.2 0.1 0.0 0.0 0.2 14.2 16.0 0.0 0.0 0.3 2.9 355.0 10.8 0.3 0.0 2.1 0.9 5.6 2.6 0.0 0.1 0.1 0.0 22.6 0.2 0.0 0.0 0.3 1.2 0.3 1.4 102.1 7.4 16.3 0.3 1.3 36.2 565.7 0.9 0.4 0.0 1.3 3.5 121.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 28.4 0.0 0.1 0.3 0.2 0.0 123.7 0.3 16.6 9.9 0.0 15.6 0.4 5.2 4.5 0.7 0.2 1.6 4.0 1.3 1.1 0.0 0.0 45.0 3.0 1.0 0.7 0.5 1.2 1.2 2.8 1.4 2.0 1.0 0.8 2.2 0.7 3.4 16.0 33.0 0.0 4.3 17.3 80.8 6.9 45.5 3.3 14.5 6.7 0.8 35.8 23.6 22.0 0.0 48.5 38.5 457.8 21.5 7.4 1.4 5.7 5.4 18.2 8.4 17.2 0.8 94.5 701.7 25.3 196.7 36.4 864.5 1.5 13.9 245.7 21.4 0.0 9.7 60.7 0.0 14.8 19.5 0.5 19.9 29.2 76.5 5.6 2.9 0.0 10.3 0.0 4.1 42.4 254.7 0.0 50.2 76.8 500.6 131.1 4.4 0.8 0.0 2.4 3.7 0.5 1.0 53.4 22.4 56.6 42.7 65.0 58.9 922.8 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 6 "Hepatocytes: 442.2;Proximal tubular cells: 201.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 31.5;Hep G2: 47.8;T-47d: 22.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 1.8 0.9 5.6 0.2 8.8 0.0 11.6 7.0 7.2 1.6 4.2 1.1 1.4 4.0 3.9 0.3 7.4 4.0 5.1 5.7 6.5 200.5 866.2 11.8 0.4 7.5 8.1 1.3 272.1 24.2 14.8 0.5 7.5 20.1 0.3 0.3 15.6 4.7 22.1 0.9 1.1 0.2 6.5 2.6 58.2 1.3 7.6 0.2 19.9 5.4 0.1 0.6 0.4 11.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.5 0.0 0.1 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.3 0.1 0.0 0.0 3.2 0.2 0.1 0.0 0.2 0.5 22.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.8 7.0 7.2 5.7 6.5 7.5 8.1 7.5 6.5 7.6 11.7 0.5 9.6 32.4 8.8 3.0 0.1 5.1 0.0 0.0 7.2 12.0 8.9 3.4 51.5 1.3 33.1 0.0 0.1 0.0 0.1 52.8 7.5 8.9 4.9 1.0 1.1 2.4 10.7 2.3 26.5 0.3 1.9 18.3 12.5 2.5 0.1 8.6 442.2 1.1 0.0 1.7 2.4 0.0 9.7 0.3 26.0 0.0 1.8 0.0 2.8 0.6 1.6 0.0 0.0 41.6 14.4 0.0 0.4 0.0 7.5 0.0 201.0 0.0 0.6 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.8 1.8 0.1 0.1 0.5 HRAS HRAS1 ENSG00000174775 "HRas proto-oncogene, GTPase" P01112 11 532242-537287 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 145.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002015, HPA049830, HPA070222" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB002015: , HPA049830: AB_2680903, HPA070222: " "unprognostic (3.06e-2)" "unprognostic (2.98e-2)" "unprognostic (7.01e-2)" "unprognostic (3.08e-3)" "unprognostic (3.49e-3)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (1.07e-1)" "unprognostic (2.25e-1)" "unprognostic (1.50e-1)" "unprognostic (2.88e-3)" "unprognostic (9.85e-2)" "unprognostic (2.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.58e-2)" "unprognostic (1.38e-1)" 28.1 24.6 64.6 3.5 67.2 2.9 27.0 62.1 86.8 30.4 58.3 34.3 2.8 23.6 12.5 80.1 18.9 3.6 56.8 64.4 64.6 33.8 21.8 27.1 4.3 65.6 65.3 20.0 20.5 13.1 38.2 9.0 66.9 38.3 6.9 10.2 27.3 12.3 59.0 69.9 19.5 8.9 64.2 20.6 24.2 16.5 64.8 9.2 20.5 25.2 10.2 34.5 44.2 65.4 59.0 105.6 44.2 25.6 22.2 17.5 39.6 49.9 25.1 64.5 29.5 62.4 29.7 20.4 10.9 63.2 60.7 43.7 46.0 114.1 19.3 19.5 108.4 6.6 43.7 56.1 38.5 13.9 12.0 28.3 118.0 42.0 51.5 19.6 31.5 34.3 29.7 32.3 40.9 110.6 34.0 50.5 26.5 39.9 94.5 31.6 40.7 18.2 47.0 33.2 87.6 43.7 25.5 55.4 17.9 31.5 43.3 14.8 35.4 47.3 44.7 16.4 39.7 20.3 17.7 15.4 39.1 17.0 38.3 0.0 0.5 0.6 0.8 0.7 0.4 0.3 0.9 0.8 0.7 2.0 0.9 0.3 0.0 0.1 4.0 0.9 1.5 0.2 64.6 67.2 62.1 86.8 64.4 64.6 65.6 65.3 66.9 64.2 64.8 65.4 51.3 12.8 10.7 9.1 18.0 131.2 101.7 25.4 82.0 46.0 38.8 75.7 25.2 22.8 11.2 35.0 18.8 78.8 21.5 72.2 74.3 35.2 1.6 36.1 28.6 32.0 29.3 11.2 9.8 37.4 63.4 25.9 33.6 34.1 2.5 26.8 22.9 17.4 39.9 48.8 10.6 26.5 4.1 11.7 38.4 7.9 17.1 21.3 64.0 10.3 12.8 50.8 11.3 4.0 12.3 48.2 30.9 23.0 26.5 61.2 30.8 54.6 20.0 37.6 32.9 20.3 40.3 5.4 21.4 118.1 145.9 78.1 22.0 18.8 26.2 106.4 HSF1 HSTF1 ENSG00000185122 "Heat shock transcription factor 1" Q00613 8 144291591-144314720 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Host-virus interaction, mRNA processing, mRNA transport, Stress response, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004239, HPA008888" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "CAB004239: AB_627753, HPA008888: AB_1079088" "unprognostic (7.08e-2)" "unprognostic (1.89e-2)" "unprognostic (6.07e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (1.55e-1)" "unprognostic (5.63e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (5.69e-3)" "unprognostic (1.05e-1)" "unprognostic (4.35e-2)" "unprognostic (1.40e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-2)" "unprognostic (2.23e-1)" "unprognostic (2.13e-1)" "unprognostic (1.12e-1)" 51.7 55.7 20.0 14.7 19.2 18.0 47.9 18.2 24.0 48.6 17.0 70.6 14.1 51.7 7.4 48.1 52.1 12.4 133.5 18.6 19.1 50.2 46.0 49.5 14.5 22.3 21.4 57.3 68.7 18.7 48.1 17.0 20.2 53.2 10.8 7.6 39.8 17.1 125.1 49.2 39.7 15.3 18.6 42.8 57.8 107.8 21.7 14.7 45.7 32.2 12.6 58.7 46.2 18.0 40.8 53.8 22.9 19.6 37.6 35.0 37.9 29.7 26.6 28.8 25.0 36.3 34.6 46.7 42.5 41.5 28.2 28.9 35.2 42.7 18.3 29.9 40.7 58.4 51.8 50.1 59.1 17.1 43.4 34.2 39.3 40.6 74.2 30.6 39.4 41.9 39.6 27.1 29.4 82.0 58.0 26.2 29.4 52.6 154.2 37.2 19.9 59.2 20.6 40.5 34.3 27.9 45.4 35.9 52.8 23.8 40.5 34.5 40.2 29.5 66.3 46.8 49.5 18.8 15.4 39.9 41.8 31.4 28.8 14.2 23.2 26.3 16.7 24.9 17.2 19.2 17.8 21.1 24.6 17.3 17.1 15.9 9.7 16.3 32.2 12.6 22.9 19.2 20.0 19.2 18.2 24.0 18.6 19.1 22.3 21.4 20.2 18.6 21.7 18.0 46.5 6.4 11.2 8.5 40.4 51.4 73.8 53.8 39.9 67.8 37.0 30.5 46.4 22.8 34.7 29.5 62.6 69.9 38.2 43.3 150.6 39.2 248.7 35.1 20.5 44.4 40.9 120.8 12.1 41.1 80.6 34.7 44.9 34.6 37.5 51.1 40.7 63.8 49.5 69.0 14.7 36.8 42.7 25.7 45.6 106.7 37.3 32.7 33.8 12.2 59.7 24.9 34.0 6.0 12.9 45.3 49.3 42.9 40.4 76.6 63.8 34.9 25.9 33.1 59.2 41.3 39.2 84.4 47.7 36.3 45.5 111.0 39.0 105.9 45.8 76.4 HSP90AA1 "FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA" ENSG00000080824 "Heat shock protein 90 alpha family class A member 1" P07900 14 102080742-102139699 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2527.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 12150.7;Urothelial cells: 5781.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002058 Approved Supported Cytosol NA NA 71000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB002058: " "prognostic unfavorable (5.59e-4)" "unprognostic (3.77e-2)" "unprognostic (1.78e-2)" "unprognostic (9.25e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-3)" "prognostic unfavorable (3.09e-5)" "unprognostic (7.79e-3)" "unprognostic (5.71e-2)" "unprognostic (7.81e-3)" "unprognostic (3.68e-2)" "unprognostic (1.65e-2)" "prognostic favorable (1.18e-5)" "unprognostic (1.04e-1)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" 362.9 439.5 1188.2 299.3 1221.3 459.2 438.6 1272.5 2527.6 282.1 1284.0 289.7 191.3 239.6 318.6 262.0 560.3 363.7 460.6 1213.8 1334.7 452.4 380.5 376.1 321.9 1283.8 1324.0 350.4 273.5 421.8 355.5 420.6 1351.6 348.4 311.1 1127.6 371.1 319.5 405.8 224.8 244.2 306.2 1216.2 217.6 297.5 541.9 1274.3 404.8 223.3 434.9 376.7 406.5 232.8 1639.1 1348.6 1832.2 1142.0 794.2 678.0 567.7 1512.1 1466.0 709.0 1779.5 994.1 1123.6 1245.6 1671.5 1323.1 960.7 1164.7 1471.2 3319.0 1452.5 3215.8 1227.4 1091.9 1291.8 1029.3 1444.3 334.9 1936.9 950.0 539.4 604.6 1140.3 416.2 1107.1 998.6 1764.9 1818.9 838.8 1634.1 1850.8 2087.7 891.1 1191.0 2500.5 1709.3 1968.2 1550.2 715.1 1030.3 1738.2 1497.0 1077.2 1860.4 1389.6 848.2 1903.9 1790.2 765.2 708.2 1234.6 786.5 1860.0 2826.4 783.5 2534.1 2402.7 1167.3 1182.5 1521.0 184.4 87.6 112.1 195.4 128.5 254.9 128.4 162.4 202.2 104.9 127.8 119.2 174.8 57.5 252.6 124.9 208.0 177.8 113.5 1188.2 1221.3 1272.5 2527.6 1213.8 1334.7 1283.8 1324.0 1351.6 1216.2 1274.3 1639.1 1571.4 1137.8 696.7 255.6 934.0 1340.7 12150.7 814.1 748.4 1185.6 1215.2 1173.1 2257.3 684.9 1020.6 513.1 2103.8 1415.1 1091.2 905.8 342.4 1210.5 662.9 2972.0 1350.8 1163.8 947.3 1502.3 158.9 867.6 1909.7 1632.5 788.5 2209.5 916.4 1026.8 341.3 554.4 1348.0 723.5 216.2 992.2 703.9 618.8 3110.7 442.6 732.0 2305.3 1300.2 267.0 773.6 1548.1 356.3 96.5 435.3 779.9 1021.6 722.9 1227.4 3791.1 552.2 896.4 2827.3 3623.6 618.0 1112.4 1974.9 3800.9 2142.4 830.1 1113.7 2050.2 3196.2 972.6 1028.8 5781.1 HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 4755.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA055729, HPA072606, HPA074351" Enhanced Supported Cytosol "Intracellular and membrane" NA Yes 63000000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB005230: AB_2121392, HPA055729: AB_2682899, HPA072606: AB_2732203, HPA074351: AB_2732252" "unprognostic (6.12e-3)" "unprognostic (2.96e-3)" "unprognostic (4.72e-2)" "unprognostic (9.24e-2)" "unprognostic (4.20e-1)" "unprognostic (1.15e-3)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (3.02e-1)" "unprognostic (9.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" 584.8 719.5 647.1 368.9 700.4 466.4 507.6 675.2 1529.5 581.3 651.0 425.3 215.8 594.2 540.1 463.8 708.5 332.5 783.8 699.9 811.5 494.6 396.5 526.9 427.7 707.0 738.2 1204.8 722.9 606.0 574.8 451.9 764.3 471.2 389.8 339.5 410.2 491.9 1379.0 483.7 332.6 526.8 655.1 346.0 538.8 251.6 745.8 362.1 456.8 998.8 571.4 525.0 509.4 818.8 2393.2 1495.7 1298.1 1606.0 871.2 904.4 1355.3 1049.1 1021.8 1898.3 1325.5 2254.5 708.0 3029.2 1106.3 1099.8 1928.1 1349.9 3197.5 1563.4 2326.7 1010.5 1292.5 2359.3 793.9 2978.8 628.9 2386.2 1563.2 842.6 1034.9 1495.5 1277.7 1658.4 1847.6 1533.9 3210.4 1095.1 1309.8 2404.3 2003.1 1432.6 1519.7 4378.9 1129.7 1900.7 1325.9 1658.7 1287.7 1422.1 1891.1 1154.8 816.3 1164.8 1526.2 1751.5 1518.6 1178.2 1169.0 1124.0 1875.7 931.1 2440.0 1255.6 2125.8 5370.7 1221.7 1720.8 1312.1 65.9 231.7 52.8 343.7 341.0 577.8 544.0 380.3 395.0 375.1 473.1 509.3 494.0 27.3 434.9 349.0 232.1 326.8 678.5 647.1 700.4 675.2 1529.5 699.9 811.5 707.0 738.2 764.3 655.1 745.8 818.8 1165.2 897.4 678.2 70.5 906.4 1059.3 4755.7 862.6 1331.1 329.3 938.9 1418.3 1407.0 519.0 942.6 366.0 227.2 1104.3 629.3 538.6 729.8 1011.1 185.5 1385.8 1359.6 1070.6 567.4 775.9 103.5 688.9 1107.1 1247.3 616.2 1444.8 1003.4 761.3 360.5 360.3 807.5 339.9 151.0 578.2 518.8 314.5 1262.5 198.4 686.0 896.7 736.4 76.8 573.3 326.1 200.8 69.9 127.4 811.7 504.8 611.2 725.0 1810.6 361.5 664.8 1219.1 262.1 348.4 1512.7 1437.2 266.1 694.1 1232.8 923.5 1123.3 1265.6 1350.0 739.6 2408.7 HSP90B1 "GP96, GRP94, TRA1" ENSG00000166598 "Heat shock protein 90 beta family member 1" P14625 12 103930107-103953931 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Plasma cells: 4874.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003901, CAB005224, HPA008424, CAB078151" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 330000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 12: NES - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB005224: AB_2119181, CAB078151: AB_2665765, HPA003901: AB_1851181, HPA008424: AB_1851184" "unprognostic (1.03e-1)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (5.70e-2)" "unprognostic (1.17e-2)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (7.22e-2)" "unprognostic (8.77e-2)" "unprognostic (8.30e-2)" "unprognostic (2.76e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.03e-10)" "unprognostic (2.95e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (1.28e-2)" 330.4 340.6 166.0 423.5 183.7 438.9 341.8 185.3 234.2 363.2 225.6 340.5 261.4 302.2 1032.5 157.5 305.5 218.9 309.5 164.4 206.2 317.1 736.4 271.1 245.9 205.0 191.3 302.6 397.1 336.0 247.2 521.1 201.6 360.2 387.5 185.6 254.9 382.8 87.5 120.0 269.5 385.7 188.8 322.4 297.6 180.7 196.5 228.2 1411.8 91.2 328.0 356.6 164.6 237.3 856.5 459.9 926.2 940.0 960.1 897.5 1229.9 1449.4 1133.4 776.0 1038.1 839.1 805.3 243.8 1102.2 1579.2 995.1 583.2 934.6 1578.9 1063.2 607.3 307.4 684.5 447.6 861.0 1457.4 702.1 514.6 519.6 690.9 920.0 1342.8 2643.7 1513.9 293.8 560.0 914.8 1039.9 314.7 409.2 768.3 756.9 925.5 544.5 372.2 597.1 1079.2 1064.3 527.1 271.5 645.7 889.2 912.0 932.7 1468.4 743.9 1016.2 854.4 566.1 476.0 462.8 607.9 945.5 949.0 455.6 1106.9 494.7 904.5 113.8 81.3 30.3 199.7 88.6 244.9 108.5 118.5 187.8 111.8 71.1 75.9 133.8 18.7 199.3 83.3 322.7 81.1 188.5 166.0 183.7 185.3 234.2 164.4 206.2 205.0 191.3 201.6 188.8 196.5 237.3 507.5 237.2 373.8 28.7 646.0 309.3 905.1 743.6 196.9 50.3 261.4 334.0 687.8 235.9 475.3 257.5 156.4 568.4 480.6 424.0 56.7 471.2 89.6 570.8 751.1 439.6 406.6 213.5 34.0 250.4 1081.0 714.0 390.9 690.9 405.3 500.6 446.9 891.9 553.1 77.4 41.9 631.5 238.0 300.1 309.8 47.0 563.2 378.4 421.6 52.5 240.5 141.0 199.8 30.2 61.3 321.8 419.1 337.7 4874.6 760.6 246.1 271.4 404.2 111.6 216.9 325.7 569.3 489.0 154.4 196.3 260.7 921.0 316.0 542.6 494.6 620.0 HSPA1L "HSP70-HOM, hum70t" ENSG00000204390 "Heat shock protein family A (Hsp70) member 1 like" P34931 6 31809619-31815283 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "testis: 63.2" "Group enriched" "Detected in many" 22 "Early spermatids: 212.5;Late spermatids: 560.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;EFO-21: 1.5;HEK 293: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043285, HPA052504" Enhanced Approved Nucleoplasm,Vesicles NA NA 53000000 "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Nucleoplasm "HPA043285: AB_10962482, HPA052504: AB_2681854" "unprognostic (1.80e-1)" "unprognostic (8.70e-2)" "unprognostic (2.52e-3)" "unprognostic (6.97e-4)" "unprognostic (2.69e-2)" "unprognostic (1.17e-2)" "unprognostic (4.24e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "prognostic favorable (1.02e-4)" "unprognostic (5.26e-3)" "unprognostic (9.96e-2)" "prognostic favorable (4.63e-4)" "unprognostic (4.48e-2)" "unprognostic (4.30e-1)" "unprognostic (1.02e-1)" "unprognostic (1.53e-3)" 1.2 1.4 0.0 0.0 0.2 0.1 0.9 1.4 0.3 1.5 0.0 1.8 0.1 1.8 0.0 0.6 2.4 0.0 1.4 0.1 0.2 1.5 1.2 1.3 0.0 0.2 0.2 2.2 0.9 0.0 1.7 0.0 0.3 1.1 0.0 0.1 1.0 0.0 3.9 1.0 1.5 0.0 0.2 2.4 1.3 63.2 0.4 0.0 1.5 0.1 0.0 1.6 1.1 0.6 0.1 1.1 0.1 0.4 0.3 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.4 0.4 0.1 0.0 0.1 0.3 4.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.3 0.1 0.2 0.2 0.2 0.3 0.2 0.4 0.6 4.2 0.0 1.1 2.9 3.5 0.9 1.3 0.4 2.2 2.6 1.9 2.0 4.5 0.0 0.9 0.0 8.4 0.6 1.4 1.4 0.0 0.7 212.5 2.0 0.7 2.2 1.8 3.2 0.6 0.2 0.6 1.3 0.0 1.3 0.0 0.9 1.8 1.1 1.3 3.3 0.8 1.4 0.0 4.4 2.5 560.9 5.0 2.1 5.4 2.8 4.1 3.6 1.0 0.5 2.0 0.4 1.4 2.2 1.9 0.9 0.9 0.6 2.2 2.8 0.0 0.8 2.9 17.0 8.7 1.7 0.1 0.4 3.8 0.9 1.5 0.3 HSPA2 ENSG00000126803 "Heat shock protein family A (Hsp70) member 2" P54652 14 64535905-64546173 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 320.2;skeletal muscle: 170.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 342.0;Distal tubular cells: 238.7;Extravillous trophoblasts: 509.9;Spermatocytes: 578.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 75.4;BEWO: 114.4;BJ hTERT+: 99.0;CAPAN-2: 52.9;SCLC-21H: 101.4" "Low region specificity" "Detected in all" "HPA000798, HPA052504" Enhanced Supported Approved Nucleoplasm,Vesicles NA NA 63000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA000798: AB_1079090, HPA052504: AB_2681854" "prognostic favorable (1.78e-4)" "unprognostic (1.72e-1)" "unprognostic (2.73e-1)" "unprognostic (1.08e-2)" "unprognostic (3.78e-2)" "unprognostic (2.90e-2)" "unprognostic (7.11e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.31e-1)" "unprognostic (3.14e-2)" "unprognostic (2.09e-1)" "unprognostic (2.60e-1)" "unprognostic (5.31e-2)" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" 9.8 6.5 83.9 7.5 161.2 0.7 6.4 148.0 116.3 12.5 84.2 94.1 5.5 51.6 18.6 42.3 17.0 5.3 39.7 88.5 96.0 73.0 4.2 14.2 3.8 170.1 122.9 5.6 8.8 7.8 15.2 61.5 174.9 10.8 9.5 1.2 16.4 4.5 170.4 31.7 29.6 28.7 128.5 20.2 18.5 121.0 125.3 3.0 2.7 60.6 5.0 42.9 16.0 320.2 30.4 75.4 11.4 0.2 8.1 0.7 114.4 42.3 99.0 16.6 27.3 2.9 52.9 7.4 16.8 46.4 3.6 33.6 0.0 2.2 10.1 4.3 5.8 0.1 4.0 0.2 7.9 0.2 10.0 3.7 1.7 2.4 0.1 4.1 1.1 0.5 0.0 6.0 8.4 13.5 0.5 0.4 8.4 11.7 9.1 6.0 0.0 0.1 26.1 4.6 101.4 5.8 1.8 3.7 0.1 3.9 2.9 3.1 1.6 0.3 0.2 3.7 0.2 7.6 0.2 0.2 9.2 0.1 11.4 0.3 0.0 0.0 0.5 0.1 0.0 0.2 0.4 0.2 0.0 0.1 0.1 0.1 0.6 0.2 0.1 0.0 1.0 0.1 83.9 161.2 148.0 116.3 88.5 96.0 170.1 122.9 174.9 128.5 125.3 320.2 74.7 0.0 5.2 18.6 21.1 54.0 31.2 35.1 342.0 1.9 37.5 57.1 39.1 5.7 8.8 132.4 0.0 42.5 30.8 29.2 238.7 8.3 35.7 56.4 63.8 59.6 28.1 0.0 0.5 5.6 509.9 40.7 83.6 54.5 13.3 1.4 32.2 0.8 15.7 0.0 1.1 63.4 24.4 3.1 25.7 27.3 8.7 24.0 30.2 6.5 0.0 14.2 0.0 2.5 157.4 5.5 15.6 7.5 7.1 7.5 8.5 1.5 4.6 2.4 26.3 48.6 66.2 578.6 77.1 175.8 42.3 75.9 29.8 4.5 12.9 11.3 HSPA4 "HS24/P52, HSPH2" ENSG00000170606 "Heat shock protein family A (Hsp70) member 4" P34932 5 133052013-133106449 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010023, CAB025529" Uncertain Approved Nucleoplasm,Cytosol NA NA 14000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "CAB025529: , HPA010023: AB_1851206" "unprognostic (2.54e-2)" "unprognostic (3.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.62e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-3)" "prognostic unfavorable (4.13e-4)" "unprognostic (2.31e-3)" "unprognostic (2.90e-1)" "unprognostic (2.40e-1)" "unprognostic (1.53e-1)" "unprognostic (2.85e-1)" "unprognostic (4.44e-3)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-1)" 31.3 36.9 33.8 41.0 37.2 35.6 26.9 38.1 63.7 26.6 52.0 31.8 26.6 27.5 29.3 62.0 26.8 27.8 50.8 39.8 43.8 44.3 47.2 26.3 47.4 37.6 41.0 21.3 29.7 43.5 24.0 37.7 45.0 26.3 34.7 104.0 27.9 26.9 57.7 26.1 26.0 35.3 38.4 28.7 26.6 62.8 40.3 40.2 39.7 41.7 60.9 48.4 23.7 48.2 160.8 215.8 147.6 241.7 137.5 114.6 267.3 171.0 127.8 162.1 199.2 408.0 163.2 264.4 175.2 165.8 382.6 138.9 259.4 282.9 232.7 122.9 148.3 195.4 136.5 225.7 109.6 122.6 163.8 115.1 117.3 209.7 136.3 92.9 157.2 126.5 207.9 79.6 179.8 141.4 173.5 91.0 202.4 123.8 98.7 156.6 180.4 140.2 146.7 207.4 117.0 96.0 163.4 84.4 234.6 273.5 124.3 118.5 139.0 146.8 210.8 127.1 206.1 90.7 215.2 199.9 125.5 198.7 149.2 29.5 22.6 24.9 18.1 35.8 21.5 34.2 16.6 19.0 27.7 42.0 17.1 16.2 14.7 22.9 27.1 10.5 18.0 18.5 33.8 37.2 38.1 63.7 39.8 43.8 37.6 41.0 45.0 38.4 40.3 48.2 30.5 64.1 47.0 12.4 74.8 41.8 116.8 25.5 52.9 58.9 30.3 26.8 113.1 28.6 47.3 22.0 54.2 67.3 38.5 42.9 27.4 48.4 68.7 54.7 48.5 40.8 47.2 46.9 24.2 49.9 66.1 45.3 38.2 46.1 54.6 66.9 19.6 32.9 64.3 35.3 24.8 34.4 36.7 28.2 40.9 31.9 23.3 50.7 30.2 21.5 55.0 60.1 22.6 18.6 24.2 50.1 24.9 25.9 66.5 61.5 27.7 49.7 60.7 152.4 26.3 41.8 85.1 107.4 101.0 71.7 41.8 87.2 58.2 68.0 39.4 69.7 HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Hydrolase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 2455.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Approved Nucleoplasm,Vesicles NA Yes 140000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Vesicles "CAB002056: , HPA052504: AB_2681854" "unprognostic (2.28e-3)" "unprognostic (1.19e-3)" "prognostic favorable (6.14e-6)" "unprognostic (1.75e-1)" "unprognostic (1.84e-2)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.65e-3)" "unprognostic (3.82e-1)" "unprognostic (9.64e-2)" "unprognostic (2.93e-1)" "unprognostic (3.22e-1)" "prognostic favorable (3.81e-4)" "unprognostic (2.53e-1)" "unprognostic (1.83e-1)" "unprognostic (2.74e-1)" "unprognostic (7.16e-2)" 539.8 604.9 456.3 542.1 498.1 442.4 448.9 591.6 887.9 326.6 571.4 435.8 506.9 367.3 614.7 554.2 498.5 508.6 892.4 535.1 614.9 850.5 763.2 480.1 685.0 564.8 564.2 421.4 1238.1 593.8 501.9 487.1 620.0 411.2 525.8 531.5 404.1 439.8 1519.0 224.4 453.5 508.4 554.2 520.3 676.7 395.0 559.8 628.6 422.6 1508.5 879.6 866.0 302.4 656.8 1369.6 2077.3 1370.5 1176.5 1259.4 1337.4 1775.6 2730.9 1550.4 3373.2 2004.8 3151.7 1787.3 2318.5 1614.6 1591.9 2337.3 1835.9 4091.6 1027.2 3323.5 1955.4 605.9 2570.4 881.5 1532.0 347.5 2418.0 1757.1 721.8 1594.5 1045.0 320.7 1753.4 1845.6 321.7 2727.8 1147.0 2704.5 1235.5 2507.0 1761.3 2063.2 3463.3 1874.0 2214.4 962.2 1281.3 1665.1 1008.4 1371.8 1023.9 1980.4 2110.5 763.6 1491.1 1837.1 901.9 1767.0 1621.1 1246.1 1404.5 2402.7 740.6 1985.0 1890.9 1791.1 3316.9 1970.0 517.7 592.3 587.8 1245.4 1159.8 1499.6 1009.2 1441.8 1366.1 656.1 752.2 1367.5 1326.5 201.8 1110.7 1255.0 465.5 1761.7 3439.4 456.3 498.1 591.6 887.9 535.1 614.9 564.8 564.2 620.0 554.2 559.8 656.8 795.5 192.3 228.2 72.5 576.3 282.3 2455.6 315.3 507.6 206.7 454.5 380.1 396.3 278.8 352.8 130.6 127.2 926.1 740.3 513.1 528.3 589.0 49.8 404.1 380.1 512.8 519.8 551.7 33.4 628.8 1032.6 609.7 366.0 366.5 434.8 633.8 249.9 223.9 810.9 181.7 45.6 511.1 303.2 359.8 1060.8 58.2 222.4 590.6 528.3 35.6 530.9 307.4 639.5 28.1 50.3 513.8 552.1 270.0 573.6 779.5 823.0 1002.2 465.7 278.1 243.3 416.3 893.1 248.9 419.2 590.6 284.6 1512.1 1123.5 430.3 632.0 1171.5 HSPB1 "CMT2F, Hs.76067, Hsp25, HSP27, HSP28" ENSG00000106211 "Heat shock protein family B (small) member 1" P04792 7 76302673-76304295 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" Chaperone "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 5909.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 16589.4;Exocrine glandular cells: 6539.7;Squamous epithelial cells: 6300.1;Urothelial cells: 13091.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 2482.8;MCF7: 3979.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000497, CAB004439, CAB047330, CAB047331, CAB047332" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 19000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB004439: AB_627755, CAB047330: , CAB047331: , CAB047332: , HPA000497: AB_1851172" "unprognostic (2.55e-1)" "unprognostic (7.25e-3)" "prognostic unfavorable (9.94e-5)" "unprognostic (7.07e-3)" "unprognostic (3.47e-3)" "unprognostic (6.61e-3)" "unprognostic (4.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (8.70e-2)" "unprognostic (2.21e-1)" "unprognostic (5.72e-2)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.56e-1)" "unprognostic (3.63e-1)" 964.4 856.4 810.6 329.6 835.1 52.3 560.5 821.6 1798.8 2123.4 864.3 2043.6 208.7 2824.2 131.7 5909.6 993.8 217.2 2981.9 776.6 944.5 986.4 554.9 790.9 99.0 894.1 838.7 731.6 751.7 221.1 303.3 324.3 870.8 979.0 73.8 10.2 1075.3 522.5 3669.8 2258.3 523.8 1066.9 808.2 224.5 770.3 99.8 840.0 218.7 627.1 628.1 279.3 1579.4 3398.4 869.5 1251.1 902.4 79.5 576.8 487.3 447.5 5.1 514.9 249.8 260.9 325.8 84.8 660.7 8.5 389.1 599.1 514.1 1094.2 359.0 279.6 76.5 690.9 106.4 41.5 611.4 345.5 267.9 69.9 466.5 542.8 2482.8 370.0 50.5 436.6 831.3 169.5 459.4 1079.7 276.5 3979.7 117.1 508.9 407.4 212.7 800.6 417.3 195.8 974.5 342.8 423.2 7.6 529.1 363.8 1323.3 456.0 224.5 1674.9 551.6 504.2 778.8 1200.3 221.7 1310.1 85.7 145.9 10.7 575.9 247.2 579.5 19.7 13.6 10.9 58.8 78.2 28.1 115.0 92.4 62.1 31.5 105.5 102.1 88.2 5.8 79.7 112.8 56.5 64.5 46.7 810.6 835.1 821.6 1798.8 776.6 944.5 894.1 838.7 870.8 808.2 840.0 869.5 708.2 272.4 186.4 78.4 145.4 1849.8 16589.4 3603.0 1728.4 243.4 312.5 174.4 822.3 264.5 1899.4 1144.0 323.2 161.7 62.0 824.2 1500.7 2021.4 11.9 1181.8 1060.9 1038.7 422.0 136.1 4.3 6539.7 399.4 998.5 219.2 1227.1 216.7 136.3 725.7 234.7 1199.8 70.7 2.2 433.0 1245.1 147.7 2828.9 30.8 299.5 1024.8 2056.2 35.6 188.0 171.4 50.4 8.0 2.7 2719.4 1417.1 534.5 296.9 3854.8 95.3 2324.4 1253.9 29.2 611.4 551.2 2129.1 20.3 105.5 6300.1 2241.7 2432.7 758.2 68.2 390.5 13091.2 HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486584-197516737 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 790.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1737.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria NA NA 18000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" 179.4 790.6 188.6 128.3 191.6 110.6 168.8 204.9 401.9 96.9 217.8 170.0 158.1 90.8 89.3 124.5 132.6 69.1 145.0 184.3 198.6 374.9 462.6 136.6 149.2 199.6 198.5 167.6 219.0 159.2 116.0 148.6 205.3 104.5 195.1 71.8 93.9 93.6 162.7 83.3 148.7 104.5 195.1 94.6 155.4 57.6 198.6 99.3 138.7 176.7 172.7 144.6 92.3 201.4 559.7 650.1 541.3 496.9 373.6 389.2 786.5 573.2 304.7 686.1 495.6 2219.1 326.2 1724.4 730.0 304.1 834.2 538.4 2232.9 633.2 943.0 417.0 888.2 1209.8 984.8 2562.8 353.2 1331.4 349.1 445.5 717.1 599.5 1053.2 471.4 542.6 919.1 1535.3 606.8 501.7 690.4 853.6 1304.2 1086.4 735.2 1424.9 1000.1 679.7 1235.5 709.5 539.7 716.5 400.8 582.0 608.5 771.0 1116.3 425.0 789.4 242.2 405.8 570.4 532.8 910.0 331.1 861.4 1399.5 485.7 795.3 456.7 12.1 52.3 11.4 36.4 81.8 71.7 63.8 59.6 54.3 84.6 54.0 81.0 70.3 11.0 62.6 72.1 49.4 51.8 70.6 188.6 191.6 204.9 401.9 184.3 198.6 199.6 198.5 205.3 195.1 198.6 201.4 216.4 166.7 172.5 38.8 220.4 246.6 1737.2 247.5 264.0 75.8 216.0 263.1 239.2 195.9 287.9 79.1 256.5 825.7 197.7 213.7 375.6 235.0 6.2 322.2 304.5 233.9 274.6 241.6 31.9 145.9 419.8 356.0 215.6 445.2 299.5 407.1 63.1 312.5 328.0 95.9 47.2 302.2 166.8 88.6 479.3 12.8 130.5 381.9 163.7 30.0 138.5 125.7 68.0 20.6 35.6 171.4 163.2 113.6 322.9 705.9 160.1 797.1 328.6 117.1 85.5 199.0 471.7 88.5 106.0 262.4 207.1 1001.2 467.2 1017.4 512.1 861.5 HSPE1 "CPN10, EPF, GroES, HSP10" ENSG00000115541 "Heat shock protein family E (Hsp10) member 1" P61604 2 197500140-197503449 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1077.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1907.6;Proximal tubular cells: 1978.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 4135.5" "Low region specificity" "Detected in all" "CAB017366, HPA038755, HPA048272" Supported NA Yes 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB017366: AB_10998950, HPA038755: AB_2676190, HPA048272: AB_2680336" "unprognostic (2.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.86e-1)" "unprognostic (1.43e-2)" "unprognostic (1.98e-1)" "unprognostic (1.85e-2)" "unprognostic (5.83e-3)" "unprognostic (4.14e-2)" "unprognostic (1.26e-2)" "unprognostic (2.94e-3)" "unprognostic (1.39e-2)" "unprognostic (6.21e-3)" "unprognostic (2.63e-1)" "unprognostic (4.51e-2)" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.08e-3)" 152.1 709.5 383.2 143.9 387.5 116.8 212.7 410.3 1077.6 122.3 402.1 257.2 164.9 84.3 213.0 132.9 131.4 97.4 208.0 383.7 400.8 410.7 662.7 111.0 154.5 400.9 394.7 130.1 112.6 173.0 125.5 164.0 399.9 137.9 246.3 85.8 121.9 114.8 181.4 80.5 168.2 116.8 403.6 86.5 130.5 58.7 391.2 144.8 104.5 213.1 207.9 216.6 85.5 440.8 593.1 926.1 675.1 521.5 560.5 314.0 905.5 586.2 307.9 620.8 577.3 2796.6 504.6 1079.2 782.2 333.8 1542.1 510.4 1895.0 681.2 782.0 512.3 874.7 1099.8 1789.0 4135.5 239.0 1503.6 497.2 382.4 532.1 577.8 297.6 392.7 631.0 720.9 1588.2 338.0 481.1 1027.2 1107.2 1706.9 1077.5 985.2 1513.4 747.6 568.2 1388.5 967.4 1028.3 581.5 375.1 546.4 713.9 545.5 1588.2 287.1 881.7 355.7 466.1 643.3 501.0 1019.4 427.8 1016.0 1758.3 515.6 726.7 640.6 33.2 95.5 24.4 166.3 174.5 216.3 287.1 223.6 210.1 156.6 221.8 251.7 264.1 12.6 200.3 143.1 263.4 198.7 176.0 383.2 387.5 410.3 1077.6 383.7 400.8 400.9 394.7 399.9 403.6 391.2 440.8 341.6 195.5 160.2 0.0 380.6 435.1 1907.6 690.4 301.7 90.7 393.6 511.2 355.6 381.8 363.3 195.0 250.2 839.3 334.4 553.8 911.7 354.0 22.3 520.7 291.3 296.3 440.3 233.1 0.0 231.2 634.0 370.0 274.2 493.3 324.6 215.7 94.6 1092.0 517.2 63.9 0.0 605.0 427.2 150.6 616.4 36.1 216.6 534.4 409.1 0.0 214.2 204.2 133.9 0.0 0.0 285.3 466.2 141.8 323.4 830.7 562.1 1978.2 475.8 160.2 131.5 283.6 642.5 140.0 241.9 381.2 371.8 976.7 685.9 791.7 775.5 1111.7 HSPH1 "HSP105A, HSP105B, KIAA0201, NY-CO-25" ENSG00000120694 "Heat shock protein family H (Hsp110) member 1" Q92598 13 31134973-31162388 "Cancer-related genes, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 1251.1" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1316.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 1251.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002060, HPA028675, HPA031569" Uncertain Enhanced Nucleoplasm,Cytosol No Yes 1300000 "Cluster 27: Non-specific - Gene expression" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "CAB002060: AB_563775, HPA028675: AB_10601581, HPA031569: AB_2673938" "unprognostic (1.10e-2)" "unprognostic (4.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.90e-4)" "prognostic unfavorable (1.41e-5)" "unprognostic (5.03e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (1.53e-1)" "unprognostic (3.13e-1)" "unprognostic (7.45e-3)" "unprognostic (9.61e-2)" "unprognostic (2.58e-1)" "unprognostic (2.04e-1)" "unprognostic (7.89e-2)" 52.2 42.1 175.9 23.5 193.6 20.7 27.9 175.2 1251.1 25.0 182.5 29.3 11.3 25.9 37.6 35.8 54.8 32.3 57.3 184.9 189.3 73.5 47.6 66.6 34.9 172.7 180.7 56.3 28.6 30.3 63.8 37.8 180.9 28.4 25.3 26.7 20.1 29.3 36.6 21.7 20.4 28.0 177.2 32.3 53.1 67.8 190.2 37.4 32.2 32.6 45.1 58.8 35.4 227.4 69.9 130.7 105.1 10.2 99.1 56.0 70.0 117.8 104.6 179.0 82.8 154.9 105.4 179.6 71.9 82.4 253.7 131.2 411.7 104.8 229.2 141.6 51.7 155.7 69.3 137.2 32.3 109.1 118.8 35.5 236.5 119.6 68.3 93.0 105.4 62.0 132.7 27.8 127.4 94.7 158.1 124.2 150.3 338.6 96.6 122.5 85.8 58.9 135.0 83.5 108.5 90.1 107.4 104.0 56.6 160.6 35.0 104.7 64.4 61.3 77.4 89.2 132.4 21.8 76.0 150.6 51.0 129.8 104.7 1.4 5.0 2.7 7.6 12.2 9.4 11.1 9.7 11.8 8.4 10.6 14.7 13.8 0.5 16.7 19.6 6.6 7.0 7.7 175.9 193.6 175.2 1251.1 184.9 189.3 172.7 180.7 180.9 177.2 190.2 227.4 171.1 131.4 87.7 36.6 130.8 214.6 1316.2 44.7 175.2 38.7 152.2 143.3 163.6 40.0 123.3 46.0 417.0 23.2 78.9 153.2 29.4 49.8 100.0 346.1 140.1 132.3 227.7 58.9 121.0 35.9 64.2 249.6 94.3 250.6 248.6 61.7 26.4 25.7 90.6 30.3 77.7 159.0 65.1 38.6 452.1 36.5 33.8 281.3 163.7 55.3 42.6 28.2 26.8 30.7 53.2 45.5 154.0 39.1 142.0 426.3 18.2 31.6 290.5 79.0 39.5 98.1 153.1 161.3 164.6 151.1 143.3 42.5 363.8 58.5 166.1 511.8 HUWE1 "Ib772, KIAA0312, UREB1" ENSG00000086758 "HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1" Q7Z6Z7 X 53532096-53686728 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Granulosa cells: 507.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002548, CAB022718" Approved Enhanced Nucleoplasm,Cytosol NA NA 73000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022718: , HPA002548: AB_1080489" "unprognostic (4.73e-2)" "unprognostic (9.06e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.56e-1)" "unprognostic (5.51e-2)" "unprognostic (1.33e-1)" "unprognostic (8.89e-2)" "unprognostic (8.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.32e-1)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" 37.7 46.1 55.6 21.1 57.4 26.7 37.4 57.6 69.6 39.8 42.0 49.4 17.6 45.6 52.6 48.4 40.7 18.5 57.1 62.6 61.3 45.2 41.8 36.1 26.6 58.7 67.8 54.0 45.9 43.2 54.2 24.0 73.2 38.4 22.7 40.0 38.9 28.6 101.0 59.3 40.2 28.8 49.1 42.5 45.5 43.0 65.1 41.2 42.9 58.1 30.3 44.6 40.2 57.2 166.8 100.4 64.0 45.4 109.2 64.8 78.5 48.8 62.6 50.2 52.3 77.0 52.2 86.6 32.3 89.4 90.4 77.8 145.6 81.8 68.3 125.6 64.6 69.1 91.9 60.5 100.2 104.5 40.6 62.4 59.8 120.8 137.6 49.7 88.3 66.4 70.3 54.5 66.3 102.4 57.0 58.2 87.7 45.4 71.3 52.0 87.9 52.8 84.0 113.3 53.1 38.4 137.7 60.5 44.1 118.7 87.0 50.1 113.8 46.0 65.8 66.5 62.9 47.3 50.2 73.1 49.2 100.1 67.6 2.8 2.3 4.3 3.3 1.9 4.0 2.4 3.1 3.5 3.3 2.4 2.2 2.2 1.9 3.5 3.8 3.5 2.9 1.9 55.6 57.4 57.6 69.6 62.6 61.3 58.7 67.8 73.2 49.1 65.1 57.2 41.4 51.3 46.1 70.2 41.9 30.1 32.6 30.4 44.9 57.8 37.0 35.6 110.4 37.1 35.4 40.5 50.1 31.0 40.0 29.2 1.9 42.8 28.6 45.6 59.8 38.3 47.6 47.7 94.4 35.4 34.8 38.6 57.1 69.6 22.1 507.7 32.9 48.1 24.8 82.4 85.8 28.1 18.3 31.4 30.8 32.8 28.3 34.1 26.6 59.0 43.7 22.6 35.0 83.9 95.3 49.3 20.5 39.1 50.9 44.1 27.1 14.7 35.7 33.3 13.1 69.6 56.4 34.5 44.6 53.3 41.6 37.9 46.7 114.1 31.7 42.0 IBSP "BSP, BSP-II, SP-II" ENSG00000029559 "Integrin binding sialoprotein" P21815 4 87799554-87812435 "Cancer-related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;pituitary gland: 2.0" "Cell type enriched" "Detected in some" 4 "Hofbauer cells: 5.8" "Group enriched" "Detected in many" 4 "breast cancer: 3.8;glioma: 12.2" "Region enhanced" "Detected in single" "thalamus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-138 MG: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.53e-2)" "unprognostic (3.55e-2)" "unprognostic (1.49e-2)" "unprognostic (3.93e-1)" "unprognostic (3.75e-2)" "unprognostic (9.48e-3)" "unprognostic (1.03e-3)" "unprognostic (4.07e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-11)" "unprognostic (6.20e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-3)" "unprognostic (2.11e-1)" 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 2.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.5 0.7 0.7 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 219.3;urinary bladder: 215.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 612.2;Alveolar cells type 2: 561.6;Endothelial cells: 240.8;Langerhans cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 158.3;Karpas-707: 459.7;RPMI-8226: 148.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 87900000 2200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Vesicles, Cytosol" "CAB002142: AB_563596, HPA002126: AB_1078470, HPA004877: AB_1846317" "prognostic favorable (7.09e-4)" "unprognostic (1.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-2)" "unprognostic (3.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.32e-6)" "unprognostic (2.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-1)" "unprognostic (3.70e-3)" 87.9 23.6 9.1 44.6 9.6 117.1 32.4 7.9 12.0 11.2 9.9 17.7 16.8 23.9 3.5 11.0 26.2 56.4 39.1 8.8 9.9 43.9 67.1 219.3 38.3 12.3 8.7 13.0 11.1 8.3 9.3 27.8 10.2 22.2 18.1 10.5 18.0 6.3 15.1 17.9 22.6 23.4 10.0 55.9 21.5 5.6 15.4 28.4 30.8 12.8 32.9 215.3 12.5 10.2 46.3 0.5 7.9 0.2 2.0 4.4 9.7 8.6 91.6 21.8 62.0 14.0 49.8 39.6 130.3 3.8 99.3 8.9 1.7 0.4 45.6 123.8 0.1 3.8 1.4 62.0 158.3 1.3 23.9 55.7 4.0 13.7 20.3 2.0 10.7 4.9 15.0 459.7 1.5 3.3 0.5 34.9 3.1 0.5 24.7 1.0 0.2 148.5 36.8 0.3 0.3 1.1 61.2 3.3 94.5 3.7 6.9 2.8 34.3 22.3 1.9 12.3 0.8 137.4 142.7 25.5 35.1 26.3 32.6 5.0 28.3 5.2 5.3 25.8 9.8 3.8 4.0 6.3 24.7 1.5 1.9 3.8 40.8 15.2 17.0 14.1 6.1 20.8 9.1 9.6 7.9 12.0 8.8 9.9 12.3 8.7 10.2 10.0 15.4 10.2 150.3 612.2 561.6 0.3 31.7 85.3 22.2 62.6 28.5 0.0 50.2 24.9 1.1 21.5 133.5 3.7 0.0 1.1 28.9 2.9 0.0 176.8 2.0 14.1 15.5 240.8 2.4 1.3 0.5 98.7 3.3 136.6 13.7 29.8 139.8 0.1 48.2 12.1 86.7 0.0 0.4 0.7 32.6 53.6 232.6 1.3 4.7 168.3 76.5 7.5 101.9 4.6 5.2 0.5 0.2 113.7 0.3 1.5 57.6 27.1 0.3 15.0 83.2 0.4 6.6 38.2 57.6 0.8 1.6 4.3 69.3 1.2 28.8 0.5 1.6 14.1 ID1 "bHLHb24, dJ857M17.1.2" ENSG00000125968 "Inhibitor of DNA binding 1, HLH protein" P41134 20 31605283-31606515 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1667.3;Basal respiratory cells: 1443.4;Hepatic stellate cells: 2131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 509.6;HaCaT: 500.2;Hep G2: 425.3;PC-3: 515.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025915, HPA051456, HPA058518" Approved Enhanced Nucleoplasm "Intracellular and membrane" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB025915: , HPA051456: AB_2681492, HPA058518: AB_2683740" "unprognostic (3.89e-2)" "unprognostic (3.45e-2)" "unprognostic (2.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.85e-4)" "unprognostic (2.29e-1)" "unprognostic (1.58e-1)" "unprognostic (2.14e-2)" "unprognostic (7.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.71e-3)" "unprognostic (2.97e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-3)" 242.2 88.5 53.0 20.2 43.1 9.0 141.3 50.1 57.1 125.7 60.9 136.7 78.4 116.0 4.7 340.4 146.3 35.0 291.9 45.3 56.8 218.1 154.1 204.7 14.0 69.3 56.0 66.8 42.4 8.1 167.8 45.7 62.3 202.5 26.4 5.1 58.5 149.6 53.8 129.6 154.3 12.2 53.3 79.7 162.5 16.4 79.1 5.9 266.8 37.8 6.2 351.1 206.9 47.1 76.1 245.3 2.7 49.3 31.2 14.1 187.6 314.1 12.6 56.9 6.2 130.5 111.4 0.6 509.6 84.3 67.2 500.2 40.1 17.9 8.6 6.2 25.6 41.5 229.2 425.3 42.3 0.9 2.2 57.4 69.7 0.3 4.3 93.5 35.0 27.6 94.0 2.3 110.4 99.8 11.4 1.8 172.7 336.5 515.3 0.9 200.8 4.2 11.1 206.1 93.5 87.4 261.3 91.9 2.4 128.8 57.0 7.6 188.5 151.3 300.0 49.0 216.1 5.6 6.3 5.2 176.2 39.5 21.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 0.2 0.0 0.0 0.1 53.0 43.1 50.1 57.1 45.3 56.8 69.3 56.0 62.3 53.3 79.1 47.1 1667.3 237.2 171.7 88.2 25.1 102.3 992.2 1443.4 406.3 2.7 98.6 114.3 35.1 112.9 685.1 228.1 4.2 129.9 46.3 594.3 37.2 584.1 5.7 794.1 450.1 907.7 572.7 49.9 0.6 535.5 493.7 195.3 675.3 707.6 22.2 8.9 2131.4 109.1 25.6 0.0 0.5 557.4 321.4 72.2 52.4 8.7 28.6 38.9 90.7 92.8 8.2 85.0 1.0 4.0 0.3 257.4 924.9 0.4 26.7 519.7 579.8 7.1 168.1 8.3 13.1 229.7 206.1 3.2 53.7 455.8 87.9 89.1 39.8 15.9 389.1 591.6 ID2 "bHLHb26, GIG8" ENSG00000115738 "Inhibitor of DNA binding 2" Q02363 2 8678845-8684461 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1209.7" "Cell type enhanced" "Detected in all" "Langerhans cells: 2393.2;monocytes: 1987.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1038.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 731.4;HEK 293: 459.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027612 Approved "Nucleoplasm,Nuclear bodies,Centrosome" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nuclear bodies" Centrosome "HPA027612: AB_10599729" "unprognostic (2.53e-1)" "unprognostic (8.16e-3)" "unprognostic (8.51e-2)" "unprognostic (6.66e-2)" "unprognostic (2.24e-1)" "prognostic favorable (9.95e-4)" "unprognostic (4.39e-2)" "unprognostic (6.31e-2)" "unprognostic (1.95e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-1)" "unprognostic (2.81e-1)" "unprognostic (5.98e-2)" "unprognostic (2.42e-2)" "unprognostic (1.74e-1)" "unprognostic (1.38e-3)" "unprognostic (1.92e-3)" 160.8 175.9 86.6 73.9 88.5 390.3 82.6 83.8 118.2 97.4 68.5 149.9 99.1 69.7 21.0 35.3 108.3 150.8 177.4 89.6 86.8 128.2 562.5 108.1 92.6 80.2 82.9 213.1 60.1 1209.7 65.7 70.3 85.2 125.1 124.7 69.7 114.3 142.4 18.9 69.6 99.4 85.3 81.4 107.4 66.7 13.8 90.1 73.8 223.5 41.2 47.4 110.2 76.2 95.8 2.0 132.4 56.0 68.6 86.8 13.9 208.5 156.6 18.3 68.4 29.1 266.0 7.3 4.1 175.1 262.5 16.9 115.9 36.0 1.0 20.7 731.4 459.5 101.3 81.7 333.9 24.8 76.5 266.3 23.4 3.1 30.5 1.9 19.2 1.4 6.7 6.2 113.9 109.1 45.3 7.8 9.0 102.4 338.5 102.9 9.7 38.4 75.6 71.3 60.5 103.5 146.6 8.4 117.8 12.1 142.0 19.3 44.9 27.5 83.9 14.5 126.5 9.4 8.9 7.9 88.7 106.6 230.2 46.5 110.3 76.0 1038.0 356.7 221.7 214.2 3.6 108.1 251.9 223.8 1.6 133.7 262.1 96.6 880.8 248.9 10.3 9.2 200.1 86.6 88.5 83.8 118.2 89.6 86.8 80.2 82.9 85.2 81.4 90.1 95.8 429.9 141.1 237.9 316.7 41.4 131.3 143.0 494.8 138.9 9.8 231.2 218.4 179.5 316.0 211.2 101.2 16.7 260.3 604.5 337.7 555.7 471.0 12.0 601.1 344.6 281.1 425.9 59.8 23.5 160.3 142.4 276.0 189.1 647.2 973.6 17.1 487.6 554.7 700.3 6.7 13.8 548.0 494.4 415.8 2393.2 21.7 124.2 528.4 282.8 15.9 1987.9 519.9 1070.1 26.7 3.2 69.6 301.9 32.7 86.0 130.1 231.3 264.1 66.7 27.4 19.7 166.6 185.6 2.1 39.9 97.6 104.6 666.0 690.0 16.7 323.1 51.3 ID3 "bHLHb25, HEIR-1" ENSG00000117318 "Inhibitor of DNA binding 3, HLH protein" Q02535 1 23557926-23559501 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Myogenesis, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1710.3;Basal respiratory cells: 1091.1;Hepatic stellate cells: 1508.2;Ionocytes: 1210.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 318.8;naive B-cell: 306.1" "Group enriched" "Detected in many" 39 "B-cells: 318.8;T-cells: 177.0" "Cell line enhanced" "Detected in many" "U-698: 598.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021353, HPA024677" Approved Supported Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB021353: , HPA024677: AB_2671647" "unprognostic (6.73e-2)" "unprognostic (2.48e-1)" "unprognostic (5.19e-2)" "prognostic favorable (1.27e-5)" "unprognostic (5.58e-3)" "unprognostic (1.46e-1)" "unprognostic (8.98e-2)" "unprognostic (7.76e-2)" "unprognostic (3.89e-2)" "unprognostic (6.47e-3)" "unprognostic (2.42e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.01e-1)" "unprognostic (4.37e-3)" "unprognostic (8.36e-2)" 163.4 49.5 42.5 22.7 37.4 6.9 114.1 38.6 51.6 81.6 39.6 89.2 29.8 84.2 15.5 42.9 134.1 39.1 177.1 39.2 70.3 93.2 31.6 99.6 26.3 59.3 52.2 106.1 41.0 8.3 120.4 51.0 49.5 110.3 22.3 10.1 39.8 108.1 41.3 62.9 76.3 20.9 48.2 41.9 89.0 6.9 53.7 34.8 195.9 52.1 13.3 131.6 90.3 42.9 24.1 152.6 57.2 199.1 27.2 2.8 53.0 154.2 16.8 105.0 14.5 8.9 1.2 150.2 168.2 80.3 21.7 216.1 77.7 25.1 12.3 1.2 68.8 2.4 227.5 89.6 77.9 0.2 0.4 80.1 141.9 2.8 1.5 104.0 91.7 67.1 0.9 2.0 107.8 59.9 21.0 0.6 41.9 140.0 37.6 189.5 82.1 5.6 1.3 66.3 78.3 55.0 148.4 155.8 12.7 49.9 38.1 5.2 162.3 151.5 72.4 69.4 92.2 47.4 45.9 598.1 34.4 1.8 79.0 0.6 1.3 0.3 3.8 1.8 1.3 318.8 69.8 13.9 5.0 306.1 113.3 45.6 3.6 0.7 2.1 6.2 177.0 36.9 42.5 37.4 38.6 51.6 39.2 70.3 59.3 52.2 49.5 48.2 53.7 42.9 1710.3 115.4 62.6 77.7 211.6 205.2 340.3 1091.1 583.4 4.1 128.3 187.3 35.8 20.0 337.1 209.7 10.4 193.4 27.8 384.8 23.5 216.6 1.9 555.2 270.3 988.8 432.3 41.0 0.1 441.5 931.4 496.5 384.3 562.4 15.2 394.7 1508.2 7.0 70.6 5.0 0.2 560.1 1210.5 71.7 254.9 3.7 41.0 91.1 249.1 62.8 21.0 378.5 1.0 0.5 3.1 88.4 388.8 0.7 67.1 168.4 223.1 7.9 110.6 17.7 519.4 266.4 780.2 0.9 2.8 577.6 189.5 279.2 86.7 19.5 323.3 116.5 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.7;placenta: 110.9" "Cell type enriched" "Detected in many" 11 "monocytes: 2612.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.0" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.0" "Cell line enriched" "Detected in some" 7 "EFO-21: 61.8" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Supported Nucleoplasm,Vesicles,Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Nucleoplasm, Vesicles, Mitochondria" "CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222" "unprognostic (1.68e-2)" "unprognostic (1.71e-2)" "unprognostic (4.08e-3)" "unprognostic (7.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "prognostic favorable (5.27e-4)" "prognostic favorable (3.32e-4)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.12e-7)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-2)" 9.8 0.7 0.6 40.5 0.4 0.7 2.0 0.4 0.8 7.2 1.0 5.3 10.3 10.2 1.2 1.3 2.6 6.2 1.8 0.4 0.6 1.7 2.4 25.9 58.7 0.7 0.3 1.2 1.2 0.2 0.1 110.9 0.5 2.0 8.2 1.3 1.9 3.0 8.1 1.3 8.4 2.4 0.4 23.0 5.8 1.1 0.8 31.2 4.0 0.6 31.5 9.1 0.5 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 7.6 4.8 0.3 0.8 0.0 61.8 0.0 3.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.1 0.2 0.2 0.0 0.3 0.0 32.5 1.3 465.0 0.1 1.4 0.1 0.2 0.1 0.0 26.4 0.3 0.1 0.2 4.9 0.1 0.1 0.3 0.1 1.2 0.6 0.4 0.4 0.8 0.4 0.6 0.7 0.3 0.5 0.4 0.8 0.6 24.9 0.0 0.5 0.7 4.4 0.4 0.2 18.3 0.0 0.0 0.5 0.1 0.3 0.0 76.0 0.0 0.0 0.0 0.3 8.3 0.0 4.4 3.7 70.1 23.0 6.9 0.0 0.0 0.2 8.1 0.0 0.3 0.0 223.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 2.0 3.7 28.1 1.8 0.0 13.6 0.0 0.0 2612.3 3.0 0.0 0.0 0.1 0.4 0.0 0.4 2.4 0.5 0.0 0.0 33.3 0.2 0.0 1.2 8.4 0.0 0.1 0.1 0.6 0.0 1.3 0.0 1.3 2.0 IFNA1 "IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA@, IFNA13" ENSG00000197919 "Interferon alpha 1" P01562 9 21440439-21441316 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.2;hTERT-RPE1: 2.2" HPA047557 Uncertain "Secreted to blood" NA NA 10000 "Cluster 20: HeLa - Mitochondria" "HPA047557: AB_2680087" "unprognostic (3.14e-1)" "unprognostic (1.55e-1)" "unprognostic (9.75e-2)" "unprognostic (5.88e-2)" 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 0.1 0.1 0.4 0.1 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNA13 ENSG00000233816 "Interferon alpha 13" P01562 9 21367424-21368962 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.4" "Cell type enriched" "Detected in single" 17 "Granulosa cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Granulosa cells - Unknown function" "HPA047557: AB_2680087" 0.0 0.0 0.8 0.0 1.4 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.2 1.0 0.6 0.5 0.6 0.7 0.5 0.1 1.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNAR1 "IFNAR, IFRC" ENSG00000142166 "Interferon alpha and beta receptor subunit 1" P17181 21 33324429-33359864 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029226 Approved NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA029226: AB_2672954" "unprognostic (2.42e-3)" "unprognostic (2.95e-1)" "unprognostic (3.01e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (3.02e-1)" "unprognostic (4.69e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (2.38e-1)" "unprognostic (9.38e-3)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (8.45e-2)" "unprognostic (3.06e-2)" 40.8 22.3 14.3 36.4 14.6 30.8 32.3 15.7 15.2 26.3 9.6 28.9 26.7 22.4 23.2 25.2 23.8 30.2 21.2 15.0 16.2 32.0 76.6 29.7 28.8 17.4 15.6 23.5 29.2 40.5 7.7 49.5 16.9 27.2 30.5 23.6 30.2 24.1 32.7 20.5 27.4 24.0 15.7 33.5 31.6 20.9 17.5 33.1 41.2 24.8 29.7 39.8 9.0 18.6 47.3 24.4 27.4 24.2 55.8 80.8 23.7 44.6 74.2 32.9 36.1 31.7 57.2 42.4 35.4 49.4 36.3 28.4 23.3 37.0 43.8 33.8 26.0 62.8 29.0 20.2 33.9 50.8 43.3 58.2 38.4 43.6 37.7 39.4 63.1 40.3 67.6 198.2 56.5 22.8 38.7 22.2 24.9 46.6 25.6 29.5 75.0 62.4 33.7 44.0 22.5 24.1 50.5 42.4 39.3 20.8 58.2 36.8 61.3 39.3 24.7 58.2 28.2 102.3 132.7 43.2 66.3 64.4 50.5 77.3 45.4 27.7 23.6 64.0 23.1 56.2 31.5 28.6 37.4 57.0 37.0 29.0 166.7 28.0 80.3 54.3 41.2 35.2 14.3 14.6 15.7 15.2 15.0 16.2 17.4 15.6 16.9 15.7 17.5 18.6 101.2 109.0 45.8 17.6 69.3 45.8 57.0 72.3 18.8 51.9 42.5 29.7 33.5 34.3 78.8 44.1 29.2 28.1 43.8 25.3 21.5 73.0 17.7 37.9 58.4 75.5 26.9 27.1 26.3 90.5 92.4 61.1 35.7 44.5 39.2 30.3 53.9 81.3 69.2 58.9 29.4 28.9 46.8 82.1 47.5 10.7 32.6 77.6 37.4 30.9 86.8 34.3 42.2 34.2 27.2 64.7 25.5 30.9 137.3 63.9 37.6 28.7 59.6 30.0 19.7 54.9 44.9 38.5 17.5 21.5 44.9 20.1 38.3 25.1 27.5 72.2 IFNAR2 IFNABR ENSG00000159110 "Interferon alpha and beta receptor subunit 2" P48551 21 33229901-33265675 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 188.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 211.2;U-266/70: 261.6;U-266/84: 145.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.00e-2)" "unprognostic (7.83e-3)" "unprognostic (4.98e-2)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-3)" "unprognostic (8.05e-2)" "unprognostic (4.17e-2)" "unprognostic (2.11e-2)" "unprognostic (7.65e-2)" "unprognostic (4.42e-1)" "prognostic unfavorable (7.54e-7)" "unprognostic (9.70e-3)" "unprognostic (2.39e-1)" "unprognostic (5.12e-3)" "unprognostic (1.85e-2)" 21.3 9.0 13.2 33.2 13.6 29.1 16.4 11.5 14.8 12.7 9.7 16.7 17.4 11.7 8.2 8.0 11.7 21.0 13.4 11.0 14.3 14.3 28.7 22.6 33.5 16.7 14.0 11.8 10.0 12.5 10.1 22.9 15.1 10.1 17.4 8.3 13.7 11.3 9.0 7.0 16.2 18.3 13.6 41.0 14.8 5.3 15.8 33.9 10.7 10.8 36.4 38.2 9.0 14.0 17.0 18.4 9.9 23.7 11.9 27.3 16.2 18.1 45.1 14.2 15.7 24.4 20.8 28.3 12.8 25.4 22.8 10.9 15.2 9.2 15.0 18.3 19.9 100.9 19.1 22.2 17.5 17.5 38.0 20.7 8.7 16.8 18.5 24.8 46.0 41.5 30.2 211.2 13.7 9.1 44.0 19.6 18.3 24.2 11.7 14.9 53.4 50.7 30.8 31.9 26.6 14.2 29.5 28.2 23.9 10.4 4.4 30.5 32.2 15.3 9.3 12.5 10.1 261.6 145.3 64.3 20.5 60.3 37.5 44.5 38.5 63.8 31.2 65.0 32.2 25.7 37.9 29.3 36.6 17.1 27.5 30.8 101.2 35.2 73.4 101.0 65.8 41.3 13.2 13.6 11.5 14.8 11.0 14.3 16.7 14.0 15.1 13.6 15.8 14.0 35.6 60.9 16.1 19.6 49.4 6.8 43.8 41.7 2.8 6.6 11.4 12.4 2.2 20.0 23.6 11.0 6.2 28.9 64.4 6.0 3.9 67.5 3.0 6.7 10.0 39.0 3.0 27.6 44.4 62.7 72.1 15.4 4.6 8.5 31.7 11.8 44.6 19.6 44.9 20.2 42.3 4.4 4.1 73.5 17.1 3.3 7.5 58.5 19.6 74.9 47.9 6.4 89.6 51.3 29.4 73.8 5.9 9.1 188.8 89.5 17.3 10.2 35.2 5.6 0.0 16.8 12.5 4.2 19.9 4.3 5.7 23.5 43.9 2.5 4.9 83.2 IFNB1 "IFB, IFF, IFNB" ENSG00000171855 "Interferon beta 1" P01574 9 21077104-21077942 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "Hofbauer cells: 2.2;Macrophages: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BJ hTERT+ SV40 Large T+ RasG12V: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA073843 Supported "Secreted to blood" NA NA 3750 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "HPA073843: " "unprognostic (2.38e-1)" "unprognostic (2.60e-4)" 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159740 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.5;lymphoid tissue: 7.4" "Group enriched" "Detected in many" 12 "dendritic cells: 283.2;T-cells: 200.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "gdT-cell: 5.5;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.6;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010344 Approved "Secreted to blood" NA NA 1470 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 7: Non-specific - Mitochondria" "CAB010344: AB_2123447" "unprognostic (2.16e-4)" "unprognostic (1.93e-3)" "unprognostic (9.21e-2)" "unprognostic (1.04e-4)" "unprognostic (5.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.33e-1)" "unprognostic (3.17e-4)" "unprognostic (7.79e-2)" "unprognostic (7.97e-3)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (7.62e-9)" "unprognostic (3.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.32e-2)" "unprognostic (7.38e-3)" 0.7 0.7 0.1 3.5 0.2 11.5 0.3 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.0 0.0 0.3 1.5 1.8 7.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.9 0.2 0.0 0.0 0.3 0.2 0.0 1.3 0.4 0.1 0.1 0.5 0.3 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.4 6.6 0.0 0.4 0.5 3.7 0.1 0.9 0.0 0.0 0.1 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.0 0.0 0.0 3.1 3.2 1.3 0.0 0.0 0.0 4.8 5.5 0.2 1.5 0.0 0.0 0.0 0.0 283.2 0.1 0.0 0.0 0.2 1.0 1.1 1.3 0.0 0.4 0.0 0.0 0.0 1.5 6.1 1.1 0.0 0.0 1.4 1.2 0.1 0.0 0.0 0.5 0.0 4.4 5.5 0.0 0.0 10.4 7.2 0.0 0.0 0.0 19.6 0.0 0.1 0.0 1.1 0.0 10.9 0.2 0.0 0.3 0.0 0.0 0.0 1.0 2.9 0.0 0.0 0.8 4.0 0.0 200.1 0.0 0.2 0.2 IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648539-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 239.4;Inhibitory neurons: 194.6;Microglial cells: 245.4;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 261.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 4.3;T-cells: 1.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010268, HPA045563" Approved NA NA 46000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "CAB010268: AB_671792, HPA045563: AB_2679368" "unprognostic (1.30e-3)" "unprognostic (5.81e-3)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (2.05e-2)" "unprognostic (1.29e-2)" "unprognostic (6.87e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (8.56e-2)" "unprognostic (1.62e-1)" "prognostic favorable (3.75e-7)" "unprognostic (1.57e-1)" "unprognostic (3.59e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" 7.3 11.3 10.1 3.6 11.2 11.0 12.2 12.0 12.0 10.1 35.5 12.5 2.5 11.0 11.1 7.5 13.0 4.5 9.6 9.5 8.2 11.6 0.9 9.5 2.7 12.4 13.4 15.8 15.4 2.1 8.8 12.1 11.2 14.7 4.5 16.0 10.0 9.6 7.0 11.1 6.5 6.1 10.3 5.8 9.6 8.4 13.2 6.1 12.9 11.6 3.4 9.9 10.0 11.1 6.1 34.0 22.6 0.2 11.9 8.3 16.3 8.0 14.5 2.5 2.2 15.6 17.5 1.6 22.1 13.8 14.7 31.6 10.9 25.0 1.9 0.1 11.1 27.5 32.3 31.2 10.4 11.1 2.5 12.1 14.9 4.5 18.6 9.3 8.4 2.8 1.4 5.4 9.9 48.1 5.4 9.8 23.0 11.8 1.3 7.7 19.3 6.7 7.4 37.8 8.1 35.9 56.0 3.3 30.1 50.2 16.7 3.8 24.5 1.5 26.5 6.5 12.0 1.9 9.8 5.9 4.6 10.0 5.9 1.9 0.3 0.9 0.4 0.2 0.2 0.1 0.3 0.1 0.1 0.4 1.4 0.4 4.3 0.5 0.3 0.1 0.0 0.3 10.1 11.2 12.0 12.0 9.5 8.2 12.4 13.4 11.2 10.3 13.2 11.1 30.8 28.9 13.4 157.7 3.5 32.8 28.8 31.1 35.3 51.5 58.3 33.4 30.8 5.7 30.2 22.0 91.8 33.7 8.0 10.7 1.9 16.6 27.6 79.7 39.6 26.1 35.0 7.8 239.4 11.2 20.3 25.2 11.2 91.3 0.0 106.5 52.5 1.5 6.5 75.7 194.6 21.1 20.3 6.6 8.3 53.4 18.0 8.3 21.4 245.4 8.5 45.6 14.4 237.7 261.0 29.1 12.9 13.5 4.3 70.9 5.3 21.8 55.4 36.1 0.0 20.4 27.6 4.0 17.2 17.9 32.0 27.5 6.4 20.9 24.5 51.5 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGF2R "CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI" ENSG00000197081 "Insulin like growth factor 2 receptor" P11717 6 159969082-160113507 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 69.5" "Cell type enhanced" "Detected in many" "NK-cells: 264.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009661, HPA011332" Supported Enhanced "Golgi apparatus,Vesicles" NA NA 190000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus, Vesicles" "CAB009661: AB_2122795, HPA011332: AB_1846276" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (2.92e-5)" "unprognostic (5.83e-2)" "unprognostic (1.72e-1)" "unprognostic (4.15e-1)" "unprognostic (3.25e-1)" "unprognostic (7.32e-3)" "unprognostic (2.32e-1)" "unprognostic (1.62e-1)" "unprognostic (1.07e-2)" "unprognostic (2.37e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-3)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (6.08e-4)" 20.3 21.9 1.8 11.4 3.7 13.3 16.0 3.9 4.3 15.2 11.7 17.4 7.4 19.3 4.8 16.7 13.9 10.7 21.8 3.2 4.2 14.8 23.9 22.2 8.2 4.3 3.6 17.0 16.6 14.3 9.5 15.3 3.8 11.0 11.6 3.2 18.4 6.7 69.5 16.5 14.7 16.0 3.2 23.2 15.5 7.7 4.8 15.9 14.5 27.2 7.8 15.3 16.5 5.9 20.8 18.1 32.6 44.6 108.4 76.4 36.9 30.1 80.4 30.3 52.8 28.3 37.2 7.3 30.9 38.4 101.7 25.4 27.0 140.0 52.0 47.7 19.4 3.6 30.0 32.1 49.2 20.7 31.2 52.7 45.4 57.6 144.8 65.4 19.2 36.0 42.2 48.2 46.4 10.1 8.8 13.4 13.1 19.3 23.2 23.2 20.6 46.1 29.9 20.8 11.3 25.4 45.0 34.5 44.8 41.4 15.7 49.4 25.3 27.0 27.9 57.3 60.4 16.7 40.2 9.1 49.0 23.7 38.9 0.5 1.0 0.8 1.1 0.3 0.4 0.2 0.5 0.4 0.2 0.2 0.5 0.7 4.4 0.7 0.4 1.3 0.2 0.3 1.8 3.7 3.9 4.3 3.2 4.2 4.3 3.6 3.8 3.2 4.8 5.9 44.7 48.1 47.3 34.6 16.7 22.2 10.0 16.0 17.1 13.0 20.2 14.7 33.6 24.3 22.1 16.5 20.9 7.5 107.0 46.2 0.0 29.3 7.5 25.8 38.7 29.6 22.3 9.5 33.0 19.4 12.3 29.9 16.8 39.7 3.8 41.7 28.9 63.4 22.2 15.2 34.2 18.4 12.2 59.4 12.8 5.2 47.5 37.6 12.4 31.9 65.9 11.7 264.7 30.7 40.0 40.8 17.2 38.4 35.9 17.1 23.2 23.6 12.2 15.1 65.7 63.7 32.6 10.9 10.4 28.9 19.7 9.3 38.8 38.8 20.9 16.7 IGFBP2 IBP2 ENSG00000115457 "Insulin like growth factor binding protein 2" P18065 2 216632828-216664436 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 956.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1379.1;Granulosa cells: 1649.7;Hepatocytes: 658.6;Theca cells: 2199.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2139.8;HMC-1: 5110.0;NB-4: 1106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077723 Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 303000000 810000000 "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA077723: AB_2686853" "unprognostic (2.58e-1)" "unprognostic (5.95e-2)" "unprognostic (1.94e-1)" "unprognostic (3.32e-3)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (9.11e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (5.04e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.22e-1)" 219.5 58.8 15.9 28.3 14.8 21.4 90.5 15.6 30.2 86.9 123.3 85.5 76.8 232.5 59.9 145.6 157.0 26.9 169.2 15.6 16.3 187.3 607.7 71.0 8.8 15.3 21.7 281.7 956.0 12.4 66.9 81.0 19.3 217.3 35.0 2.4 76.4 196.2 23.3 30.8 44.6 49.7 13.2 398.9 492.2 58.0 16.0 33.6 57.8 21.9 14.5 132.6 97.4 13.2 0.1 52.3 402.1 396.3 2139.8 652.9 8.5 125.2 61.9 6.1 0.6 1.2 1.5 0.1 171.7 0.8 15.2 11.5 145.4 156.9 0.6 0.8 84.9 91.3 0.2 26.3 53.3 38.6 5110.0 219.3 15.8 2.5 7.1 12.5 0.2 184.7 3.9 11.7 2.8 103.1 162.8 1106.5 437.4 98.2 4.8 139.2 9.1 2.0 2.0 117.1 84.1 443.4 0.3 3.4 2.6 362.2 332.4 67.3 0.5 1.6 2.4 1.6 6.2 6.2 0.9 9.7 6.0 177.4 478.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 15.9 14.8 15.6 30.2 15.6 16.3 15.3 21.7 19.3 13.2 16.0 13.2 354.3 3.2 0.6 2.0 3.3 13.8 534.0 238.2 19.4 0.2 79.0 498.0 12.5 11.5 40.1 264.8 2.1 1.8 5.4 86.4 29.4 3.0 1.0 153.2 1379.1 149.2 321.0 31.1 4.5 128.4 7.7 296.7 411.8 176.0 4.5 1649.7 92.1 658.6 5.3 0.0 0.8 191.6 54.9 24.1 5.0 4.9 5.6 21.8 3.6 13.1 1.3 3.6 3.1 1.0 1.0 60.7 51.3 79.4 0.4 255.7 4.2 1.2 195.9 1.7 105.2 17.9 435.7 6.0 35.8 103.3 5.5 2.2 16.0 2199.1 133.8 304.0 IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 1864.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 457.7;Basal respiratory cells: 777.7;Extravillous trophoblasts: 2064.1;Fibroblasts: 463.4;Urothelial cells: 809.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 54.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 54.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 8578.6;U-2197: 3469.4;U-87 MG: 1774.2" "Low region specificity" "Detected in all" CAB010360 Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3250000000 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" 350.6 16.2 15.6 28.5 20.2 1.2 278.2 12.2 24.1 291.8 18.9 96.7 67.8 547.3 43.1 28.2 130.9 44.6 284.6 16.5 22.5 65.9 721.3 37.5 68.3 20.7 13.7 233.1 14.4 28.0 98.1 1864.4 21.0 87.4 58.4 11.9 46.2 81.1 57.9 176.5 77.9 198.1 12.8 191.0 81.7 10.8 16.5 18.2 40.8 73.3 67.4 369.7 165.3 15.9 199.6 59.5 113.1 1.0 83.9 34.7 0.9 850.6 153.8 71.9 38.8 0.2 157.4 0.2 263.2 8578.6 35.6 466.5 1.5 3.4 29.2 0.6 0.1 0.3 20.8 0.2 21.9 0.4 1.6 285.7 12.8 15.1 53.8 112.3 0.7 0.0 0.1 3.2 26.8 1.2 1.3 1.4 7.8 1.8 10.9 0.8 0.4 81.4 53.2 423.6 13.6 32.7 293.9 11.4 15.3 250.6 1.5 0.7 0.5 815.4 1.7 3469.4 49.3 11.6 0.7 1.1 1774.2 0.3 282.1 0.0 0.0 0.0 10.1 0.0 8.0 0.0 10.9 10.7 0.0 0.0 4.9 8.1 0.1 0.0 0.0 54.5 0.8 4.5 15.6 20.2 12.2 24.1 16.5 22.5 20.7 13.7 21.0 12.8 16.5 15.9 260.4 3.2 3.9 0.7 1.9 457.7 148.9 777.7 8.0 2.8 12.6 30.4 12.6 8.6 409.7 228.1 0.0 94.1 10.0 0.7 11.7 145.6 1.3 32.3 220.1 168.0 273.7 5.3 2.5 2.0 2064.1 463.4 1.5 31.3 1.3 12.2 182.0 2.6 80.9 0.0 5.6 8.4 57.0 7.2 21.9 3.5 288.3 3.5 16.0 1.9 7.2 0.6 0.0 0.5 0.2 19.0 2.5 6.8 1.0 212.1 0.8 1.0 136.0 0.5 0.0 12.6 124.6 0.8 1.4 9.3 244.6 154.2 9.3 3.6 2.0 809.9 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332460 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favorable (1.46e-6)" 9.4 8.2 9.1 4.7 9.8 4.8 8.3 9.2 10.9 7.2 11.7 6.8 4.8 8.1 7.3 10.2 11.6 8.6 5.6 9.2 9.5 6.8 6.6 11.3 12.2 10.5 9.9 6.1 6.2 13.5 4.0 8.2 10.0 7.9 6.8 12.3 8.9 9.3 13.7 11.4 4.9 12.7 9.7 10.5 5.5 3.2 10.1 10.8 9.4 24.3 11.6 11.1 6.8 10.2 6.2 15.7 8.0 13.6 17.3 18.9 5.8 9.2 18.2 15.2 17.2 3.1 13.9 14.1 10.0 16.5 12.5 5.6 8.4 18.3 17.8 9.8 10.8 17.8 7.8 5.9 20.9 6.1 24.0 12.3 13.7 15.0 19.1 36.1 20.7 11.6 12.8 6.9 34.6 5.1 13.9 11.3 6.1 18.9 6.0 11.1 15.3 10.0 19.6 5.7 1.3 4.7 6.4 6.4 11.7 10.0 8.7 23.6 13.6 7.2 3.9 13.9 6.1 2.8 4.0 10.3 13.8 7.6 16.7 7.4 5.0 5.6 4.6 4.1 4.3 4.4 5.1 5.5 3.7 4.8 4.8 4.7 5.2 5.1 5.5 8.5 5.9 2.9 9.1 9.8 9.2 10.9 9.2 9.5 10.5 9.9 10.0 9.7 10.1 10.2 31.3 12.8 26.9 19.2 28.4 24.3 34.1 13.9 25.6 12.7 20.6 15.5 8.8 14.3 15.4 16.5 135.5 10.4 34.1 15.9 1.9 13.4 2.3 13.9 15.6 27.4 11.4 10.1 19.7 13.6 5.3 12.4 21.9 16.5 38.0 24.0 19.6 12.0 18.6 18.5 20.6 16.4 8.2 32.3 24.0 3.4 16.4 23.4 19.6 58.1 33.7 8.7 47.4 17.1 30.2 16.6 15.0 12.8 18.2 31.9 13.2 5.5 20.2 47.9 6.6 13.1 11.4 4.8 7.0 17.8 29.1 15.2 24.3 6.2 14.1 30.8 IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 173.0;lymphoid tissue: 112.5" "Cell type enhanced" "Detected in many" "B-cells: 120.5;dendritic cells: 221.4;Erythroid cells: 89.8;Microglial cells: 91.8;monocytes: 106.6;NK-cells: 150.4;Plasma cells: 128.9;T-cells: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 140.4;HDLM-2: 258.6;HMC-1: 220.4;JURKAT: 128.9;MOLT-4: 184.3;REH: 192.3;U-698: 342.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" 5.0 3.2 3.5 53.0 3.4 173.0 4.4 4.0 3.9 3.6 3.3 7.6 7.0 2.5 2.3 4.8 2.2 7.7 1.5 3.0 4.0 1.4 4.9 11.6 87.1 7.7 5.2 1.6 0.8 0.8 0.6 3.6 7.5 2.3 6.8 0.2 4.6 1.9 1.0 2.0 15.6 4.0 7.3 48.6 12.0 1.7 8.7 112.5 2.1 1.2 73.8 9.6 1.8 10.3 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 258.6 0.2 52.1 0.0 0.0 0.0 84.5 220.4 0.0 0.0 0.0 0.0 0.0 0.0 128.9 72.4 15.4 0.0 0.0 184.3 80.9 2.4 0.0 0.0 192.3 0.3 39.6 0.0 0.0 1.6 2.0 0.8 1.0 0.8 0.4 0.2 112.1 0.2 0.0 1.9 0.2 0.4 80.8 49.4 342.7 0.5 89.5 0.5 21.2 14.2 25.0 35.4 43.9 29.1 46.7 36.3 35.0 15.1 40.7 48.2 35.7 20.2 24.3 43.3 23.4 32.6 26.4 3.5 3.4 4.0 3.9 3.0 4.0 7.7 5.2 7.5 7.3 8.7 10.3 2.8 3.2 12.2 0.7 120.5 2.8 0.1 0.0 0.0 0.0 2.8 1.9 1.5 2.8 1.8 1.8 0.0 0.4 221.4 0.3 0.0 0.4 3.8 0.5 0.4 2.6 0.0 89.8 0.2 0.0 0.4 2.5 4.6 0.6 23.4 0.2 3.9 2.0 30.6 0.0 0.3 0.0 0.0 64.3 61.0 5.3 0.0 72.1 19.6 91.8 106.6 0.0 150.4 1.0 0.3 0.1 0.4 0.0 128.9 0.1 0.0 1.0 1.5 0.1 0.0 1.5 1.6 0.1 2.1 0.5 2.7 0.7 182.8 0.1 0.1 0.1 IL10 "CSIF, IL-10, IL10A, TGIF" ENSG00000136634 "Interleukin 10" P22301 1 206767602-206774541 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.7;lymphoid tissue: 7.7" "Group enriched" "Detected in some" 4 "Hofbauer cells: 28.3;Kupffer cells: 44.4;Langerhans cells: 35.5;Macrophages: 99.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in some" "thalamus: 3.5" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1;intermediate monocyte: 1.8" "Lineage enriched" "Detected in single" 6 "monocytes: 2.1" "Group enriched" "Detected in some" 11 "HMC-1: 14.6;U-266/70: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013120, HPA071391" Approved "Secreted to blood" NA NA 5670 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "CAB013120: , HPA071391: " "unprognostic (3.65e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.63e-3)" "unprognostic (2.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (4.26e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-1)" "unprognostic (4.66e-4)" "unprognostic (7.11e-2)" "unprognostic (1.93e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-2)" 6.7 2.1 0.1 7.7 0.1 3.2 0.7 0.2 0.7 0.8 0.9 1.0 0.8 0.3 0.1 1.5 1.4 3.5 1.1 0.2 0.5 0.2 1.6 1.5 5.7 0.7 0.4 0.4 0.1 0.2 0.4 1.9 0.6 0.4 1.3 0.0 0.2 0.7 0.0 0.1 1.1 3.1 0.5 4.9 0.8 0.8 3.5 2.9 0.2 1.2 2.0 2.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.2 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.1 0.1 0.2 0.7 0.2 0.5 0.7 0.4 0.6 0.5 3.5 1.2 0.5 0.0 1.9 0.0 5.6 1.0 0.4 0.0 0.0 0.2 0.2 0.3 0.3 0.0 1.3 0.0 0.0 0.1 1.3 0.0 0.0 0.0 6.9 0.1 0.2 1.9 0.0 0.4 0.0 0.0 0.1 0.8 1.1 0.2 1.3 0.0 0.7 0.5 28.3 0.0 0.0 0.0 0.0 44.4 35.5 2.9 0.0 99.5 1.8 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.4 0.0 0.9 0.8 0.0 0.2 0.7 1.1 0.1 12.9 0.0 0.0 0.4 IL11 "AGIF, IL-11" ENSG00000095752 "Interleukin 11" P20809 19 55364382-55370463 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Pancreatic endocrine cells: 64.4;Smooth muscle cells: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 50.9;BJ hTERT+: 60.0;HBF TERT88: 39.0;hTEC/SVTERT24-B: 47.9;U-251 MG: 187.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 34800 "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (6.60e-3)" "unprognostic (7.23e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (3.32e-3)" "unprognostic (6.33e-2)" "unprognostic (1.04e-2)" "unprognostic (7.84e-5)" "unprognostic (2.47e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (4.83e-2)" "unprognostic (4.07e-8)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.82e-3)" "unprognostic (3.08e-2)" 0.7 0.2 1.1 3.6 0.6 0.9 0.3 2.2 1.3 0.3 0.3 1.0 0.2 2.9 0.3 1.2 0.2 2.8 0.5 0.6 2.6 4.7 0.2 1.2 0.0 3.3 2.6 0.4 0.3 0.0 4.4 1.1 2.6 2.7 0.1 0.5 0.6 0.6 0.0 1.5 0.5 0.3 1.3 0.3 3.7 1.7 2.9 0.3 0.1 0.0 0.1 2.4 0.5 0.5 2.3 1.4 0.5 0.9 0.0 0.0 0.5 50.9 60.0 26.6 35.2 1.2 1.3 0.7 2.5 5.1 14.4 3.0 0.3 1.4 39.0 2.4 1.7 0.2 4.3 3.8 3.1 0.0 0.3 0.3 1.5 47.9 0.3 12.4 0.0 0.2 0.4 1.8 3.4 1.5 0.1 0.4 1.2 2.1 4.2 0.2 16.9 0.3 0.4 0.5 2.9 2.0 6.8 1.2 1.4 6.8 0.8 0.3 0.7 16.1 20.0 0.2 187.4 1.0 2.5 0.4 33.9 0.4 8.9 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.1 0.6 2.2 1.3 0.6 2.6 3.3 2.6 2.6 1.3 2.9 0.5 0.3 0.0 0.5 0.3 0.3 3.2 0.6 4.4 1.2 1.7 0.4 1.8 1.1 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 12.7 0.9 3.6 1.8 0.5 0.0 0.0 0.6 2.8 1.2 12.7 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.0 0.6 1.8 0.0 1.0 0.2 0.0 0.0 0.1 64.4 1.2 1.5 0.0 1.3 0.0 0.2 0.4 0.6 0.0 0.4 51.8 0.4 1.6 0.5 0.6 0.3 0.2 0.0 0.3 0.9 IL12A "CLMF, IL-12A, NFSK, NKSF1, p35" ENSG00000168811 "Interleukin 12A" P29459 3 159988835-159996019 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 3.9;Ionocytes: 4.1;Oligodendrocyte precursor cells: 4.0;Respiratory ciliated cells: 6.1;Sertoli cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 8.1;HDLM-2: 13.2;SK-BR-3: 17.6" "Region enhanced" "Detected in single" "cerebral cortex: 2.8" "Not detected" "Not detected" HPA001886 Uncertain "Secreted to blood" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA001886: AB_1079132" "unprognostic (6.23e-2)" "unprognostic (7.82e-5)" "unprognostic (1.25e-1)" "unprognostic (3.10e-2)" "unprognostic (4.22e-1)" "unprognostic (7.18e-2)" "unprognostic (4.18e-5)" "unprognostic (2.22e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (9.57e-10)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (9.61e-2)" 0.3 0.4 0.9 0.6 0.9 1.5 0.7 0.9 2.0 0.2 0.3 0.8 0.5 0.3 0.1 4.1 2.1 0.2 0.8 0.8 0.8 0.4 0.1 2.1 0.8 0.9 1.1 0.5 0.5 0.0 0.5 0.1 1.0 0.3 0.4 0.1 0.3 0.1 0.2 0.1 0.8 0.2 0.7 1.2 0.5 0.3 0.9 0.4 0.2 0.7 0.5 0.7 0.6 1.1 3.1 0.3 0.4 2.6 0.0 0.2 0.2 3.3 2.1 3.9 8.1 1.2 0.1 0.0 0.2 0.5 4.5 0.3 0.8 0.5 3.6 13.2 4.1 0.1 0.2 0.9 2.5 0.7 6.1 0.6 1.0 6.9 2.7 2.7 1.2 0.3 0.0 2.1 2.4 0.1 0.1 0.0 0.4 0.1 1.8 2.4 0.0 0.4 0.4 0.2 0.1 1.2 0.0 17.6 0.5 0.6 0.9 1.4 0.9 0.8 0.8 2.3 6.3 1.4 0.0 0.0 1.5 5.9 0.8 0.0 0.0 0.5 0.3 0.1 0.5 0.5 0.1 0.6 0.0 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.9 0.9 0.9 2.0 0.8 0.8 0.9 1.1 1.0 0.7 0.9 1.1 1.0 0.0 0.6 1.0 3.4 0.1 2.1 1.0 1.2 0.0 1.6 2.2 0.4 0.0 1.1 0.0 0.0 0.1 0.7 0.3 0.0 1.5 0.0 3.9 0.2 1.4 2.4 0.8 0.1 0.0 0.0 0.4 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.0 1.9 0.9 4.1 0.3 0.3 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 4.0 1.3 0.4 0.2 0.0 2.1 2.9 0.1 0.0 6.1 0.0 6.6 1.5 0.3 0.4 2.9 2.6 0.1 0.0 0.7 0.1 0.5 1.3 IL13 "ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600" ENSG00000169194 "Interleukin 13" P35225 5 132656263-132661110 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 24.3" "Cell type enhanced" "Detected in some" "Early spermatids: 96.7;Late spermatids: 200.7;Spermatocytes: 44.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 187 "HDLM-2: 41.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA042421 Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 40000 "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042421: AB_10795504" "unprognostic (2.17e-1)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.92e-1)" "unprognostic (5.21e-3)" "unprognostic (1.79e-1)" "unprognostic (2.69e-1)" "unprognostic (5.20e-1)" "unprognostic (7.10e-2)" "unprognostic (3.61e-3)" "unprognostic (3.34e-1)" "unprognostic (5.97e-4)" "unprognostic (4.70e-2)" "unprognostic (2.05e-1)" "unprognostic (7.39e-2)" "unprognostic (1.38e-1)" 0.3 0.0 0.1 0.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 96.7 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 200.7 2.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.5 44.4 1.2 0.0 0.6 0.0 14.7 0.0 0.0 0.0 IL13RA2 "CD213a2, CT19, IL-13R, IL13BP" ENSG00000123496 "Interleukin 13 receptor subunit alpha 2" Q14627 X 115003975-115019977 "Cancer-related genes, CD markers, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.0;testis: 30.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 322.4" "Cancer enhanced" "Detected in many" "glioma: 17.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 133.0;U-2197: 425.6;U-251 MG: 297.4;U-87 MG: 167.9" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Low region specificity" "Detected in some" "HPA045831, HPA067363" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "Nucleoplasm, Vesicles" "HPA045831: , HPA067363: " "unprognostic (1.97e-1)" "unprognostic (2.83e-1)" "unprognostic (6.62e-4)" "unprognostic (7.39e-2)" "unprognostic (8.45e-2)" "unprognostic (1.80e-1)" "prognostic favorable (3.55e-4)" "unprognostic (3.54e-1)" "unprognostic (2.85e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-3)" "unprognostic (2.19e-2)" "unprognostic (1.53e-5)" "unprognostic (1.58e-1)" "unprognostic (1.63e-1)" "unprognostic (9.70e-3)" "unprognostic (1.20e-1)" 0.8 4.8 1.3 4.0 1.9 0.0 0.4 0.1 1.1 1.1 1.6 0.4 0.3 0.8 4.4 0.6 0.1 0.8 0.7 1.5 10.6 3.6 10.0 1.4 0.1 3.1 3.7 0.1 0.1 0.5 12.0 0.4 1.8 4.1 0.7 0.0 0.9 3.5 0.0 0.2 0.3 0.3 0.7 0.2 0.1 30.0 6.1 2.1 1.2 0.1 0.1 4.4 0.2 0.8 0.4 0.0 4.6 0.1 0.7 3.6 0.0 29.2 28.0 0.1 0.1 0.0 0.0 0.0 0.5 14.6 46.6 0.1 0.0 5.2 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.1 4.8 0.8 4.6 26.9 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 133.0 0.0 0.0 0.0 2.4 0.2 0.0 6.8 2.1 0.3 0.4 0.0 0.1 0.4 0.0 14.7 0.4 425.6 297.4 0.0 0.2 0.1 167.9 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.9 0.1 1.1 1.5 10.6 3.1 3.7 1.8 0.7 6.1 0.8 0.3 0.0 0.0 0.0 0.1 0.1 4.7 0.3 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 322.4 0.4 0.3 1.3 4.2 0.0 0.4 0.0 0.0 10.3 0.0 0.4 0.0 0.0 46.4 0.4 0.0 0.0 0.6 0.0 0.0 2.8 0.3 58.6 2.8 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 8.5 0.0 4.9 0.1 10.9 0.0 0.0 2.9 0.0 0.0 0.0 3.4 63.1 4.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 IL15 "IL-15, MGC9721" ENSG00000164136 "Interleukin 15" P40933 4 141636583-141733987 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.0;monocytes: 72.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 17.6;Karpas-707: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004457, HPA037738" Approved Supported "Nucleoplasm,Nuclear speckles" "Secreted to blood" NA NA 182000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear speckles" "CAB004457: AB_2124575, HPA037738: AB_2675640" "unprognostic (1.10e-2)" "unprognostic (1.53e-1)" "unprognostic (1.04e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (5.20e-2)" "unprognostic (1.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.09e-1)" "unprognostic (4.03e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" 7.7 3.4 1.3 7.1 1.4 4.0 6.0 2.1 1.8 5.3 1.4 7.7 6.1 4.5 2.5 4.4 4.5 4.9 5.1 1.2 1.3 7.9 3.6 7.8 9.7 2.3 1.3 1.5 2.7 0.7 3.6 3.1 1.8 4.1 5.3 4.3 3.6 2.7 8.6 3.4 10.0 4.6 1.5 15.4 4.8 2.5 1.8 6.8 15.6 3.4 6.6 4.5 6.4 1.9 2.8 6.3 0.3 0.6 0.9 5.4 1.6 6.7 6.1 6.8 5.5 3.4 8.1 2.5 8.5 6.2 6.0 4.4 0.1 3.4 3.6 17.6 1.7 0.5 16.7 0.5 4.5 1.9 1.3 2.1 1.5 4.4 0.5 13.7 4.3 2.3 4.0 18.8 4.2 0.9 4.2 0.3 3.3 2.3 1.7 1.0 16.0 0.5 9.2 0.8 0.6 1.6 3.1 4.7 3.2 0.8 0.9 0.3 6.6 6.9 4.3 2.0 4.2 13.0 1.8 1.0 7.2 0.8 2.5 10.4 16.1 0.6 2.7 15.1 5.0 4.1 3.3 2.5 5.5 4.0 1.4 1.4 1.2 3.2 16.5 0.2 2.0 6.1 1.3 1.4 2.1 1.8 1.2 1.3 2.3 1.3 1.8 1.5 1.8 1.9 14.8 0.0 2.8 0.3 9.9 6.1 2.5 2.1 2.2 0.6 2.1 1.3 2.9 2.8 5.3 5.5 0.0 1.2 5.0 4.7 0.0 9.4 6.6 6.9 78.0 14.8 0.0 1.3 2.0 14.0 1.6 5.5 4.1 5.9 0.0 0.9 11.4 2.5 4.7 0.0 4.8 5.4 0.0 17.0 22.1 2.5 2.8 16.7 8.8 4.7 72.0 21.1 8.2 3.0 0.2 19.8 8.2 1.2 9.3 6.2 9.9 12.0 3.9 0.9 6.6 7.6 4.0 1.2 0.8 5.6 3.4 0.3 6.0 0.1 2.6 3.0 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 IL17A "CTLA8, IL-17, IL-17A, IL17" ENSG00000112115 "Interleukin 17A" Q16552 6 52186375-52190638 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in single" 14 "T-cells: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Karpas-707: 2.7;U-266/84: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA052258 Uncertain "Secreted to blood" NA NA 9920 "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA052258: " "unprognostic (5.55e-1)" "unprognostic (2.18e-4)" "unprognostic (3.05e-4)" "unprognostic (1.41e-2)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.2 IL17B "IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7" ENSG00000127743 "Interleukin 17B" Q9UHF5 5 149371324-149404202 "Cancer-related genes, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 44.8;Peritubular cells: 13.2;Sertoli cells: 26.3;Smooth muscle cells: 7.6;Theca cells: 9.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "basophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cell line enhanced" "Detected in some" "HEL: 1.3;Karpas-707: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042441 Uncertain "Secreted to blood" NA NA 75000 "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" "HPA042441: AB_10797014" "unprognostic (2.83e-4)" "unprognostic (2.71e-2)" "unprognostic (4.90e-3)" "unprognostic (9.22e-2)" "unprognostic (7.43e-2)" "unprognostic (5.03e-2)" "unprognostic (9.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (6.54e-2)" "unprognostic (9.30e-3)" "unprognostic (3.22e-1)" "unprognostic (6.98e-8)" "unprognostic (2.66e-1)" "unprognostic (1.53e-1)" "unprognostic (6.47e-2)" "unprognostic (1.10e-1)" 1.4 2.2 0.0 1.0 0.0 0.2 2.9 0.5 0.1 3.2 0.0 3.1 0.3 4.3 0.0 1.5 1.1 0.4 1.1 0.0 0.0 0.7 0.0 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 2.4 0.1 0.4 2.8 2.1 0.3 0.9 1.3 2.2 0.0 0.6 0.8 3.7 0.0 0.0 0.1 0.2 0.0 1.4 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.8 44.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.1 0.2 0.6 1.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 1.0 1.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 26.3 0.6 7.6 0.1 0.1 0.0 0.3 0.0 0.0 9.9 0.0 0.1 IL18 "IGIF, IL-18, IL-1g, IL1F4" ENSG00000150782 "Interleukin 18" Q14116 11 112143253-112164096 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.5;skin 1: 149.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Basal respiratory cells: 186.4;Basal squamous epithelial cells: 215.1;Kupffer cells: 241.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 117.9;CAPAN-2: 182.3;HaCaT: 167.0;HBEC3-KT: 125.8;hTCEpi: 188.5;PC-3: 110.2;U-2 OS: 208.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003980, CAB007772" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" NA Yes 196000 16000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Golgi apparatus" Cytosol "CAB007772: AB_562304, HPA003980: AB_1851670" "unprognostic (2.31e-3)" "unprognostic (3.25e-1)" "prognostic favorable (2.78e-4)" "unprognostic (3.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (8.15e-2)" "unprognostic (3.23e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-3)" "unprognostic (4.13e-1)" "unprognostic (3.58e-2)" "unprognostic (1.51e-1)" "unprognostic (3.19e-2)" "unprognostic (3.15e-2)" "unprognostic (9.01e-2)" 19.9 6.1 5.3 18.2 5.4 31.6 12.6 5.9 8.6 38.0 7.0 34.1 22.0 2.4 3.3 124.5 8.0 23.0 3.0 5.3 6.0 23.8 9.1 23.0 67.8 7.5 6.2 1.9 17.9 1.3 2.9 6.7 7.4 6.1 29.1 6.9 15.0 3.0 6.0 149.6 22.0 3.6 6.7 29.3 13.4 1.9 5.7 8.0 3.7 2.1 25.7 25.3 77.0 11.3 117.9 40.0 0.0 0.4 0.0 0.0 0.7 2.0 0.0 0.0 0.1 22.4 182.3 0.1 25.7 0.3 3.2 167.0 0.0 125.8 0.0 0.3 1.2 17.5 35.6 9.9 3.9 9.3 32.6 0.2 188.5 0.3 43.5 0.2 0.1 0.1 0.5 0.3 1.6 0.2 0.2 0.9 0.2 31.9 110.2 0.1 0.1 0.4 79.9 24.8 0.1 0.0 78.4 52.1 0.5 1.0 31.0 25.4 0.3 0.4 208.9 1.2 35.9 0.4 0.3 0.6 0.2 67.1 0.2 6.8 8.7 16.0 0.1 10.9 0.0 0.7 0.1 0.0 25.8 0.7 0.0 0.5 9.5 19.6 6.3 5.6 0.0 2.5 5.3 5.4 5.9 8.6 5.3 6.0 7.5 6.2 7.4 6.7 5.7 11.3 1.0 173.1 38.4 0.7 6.0 122.9 33.5 186.4 215.1 2.6 4.6 7.7 1.0 41.5 66.1 9.2 0.0 2.3 10.8 109.9 80.3 24.7 2.4 94.9 1.4 4.6 14.5 26.3 3.8 143.0 3.7 18.8 20.9 32.5 101.2 2.8 8.2 1.9 68.4 0.0 4.6 30.1 57.0 241.0 37.3 1.9 0.0 123.8 3.6 61.8 38.8 2.7 6.2 2.0 1.1 161.4 104.6 4.5 4.6 23.6 67.5 22.3 69.6 39.1 6.6 0.6 3.9 1.5 1.3 152.6 111.2 1.8 9.6 0.3 47.8 90.5 IL1A "IL-1A, IL1, IL1-ALPHA, IL1F1" ENSG00000115008 "Interleukin 1 alpha" P01583 2 112773925-112784493 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.3;testis: 10.4;urinary bladder: 26.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.6;Club cells: 9.8;Endometrial ciliated cells: 11.5;Glandular and luminal cells: 29.4;Macrophages: 30.6;Squamous epithelial cells: 9.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.3;urothelial cancer: 17.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HBEC3-KT: 447.6;hTCEpi: 216.2;hTERT-HME1: 283.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10800 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "unprognostic (3.41e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.99e-2)" "unprognostic (4.28e-2)" "unprognostic (2.08e-1)" "unprognostic (8.03e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-3)" "unprognostic (1.22e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (4.03e-4)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (8.62e-2)" 0.5 0.0 0.3 1.3 0.4 1.0 0.4 0.5 0.4 4.8 0.2 0.3 0.1 2.5 0.8 13.3 0.1 2.3 0.0 0.4 0.5 0.0 0.0 2.3 0.3 0.9 0.8 0.0 0.0 0.4 0.2 1.5 1.0 0.1 0.2 0.1 1.2 0.4 0.0 0.8 0.1 0.0 0.7 0.3 0.1 10.4 0.5 0.3 0.2 0.0 8.7 26.0 1.3 1.2 12.5 0.0 0.5 0.0 0.1 0.0 0.2 0.4 13.5 0.0 0.2 0.5 0.8 0.0 52.5 0.0 65.9 3.6 0.0 447.6 1.7 0.1 0.1 0.1 0.7 0.2 1.0 0.2 0.1 0.0 216.2 3.8 283.4 3.4 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.2 0.2 0.5 0.0 0.0 0.0 0.1 55.0 0.1 0.0 1.6 0.0 0.0 0.6 0.0 0.1 1.7 1.3 0.6 0.3 0.3 0.0 0.1 0.2 5.2 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.4 0.4 0.5 0.9 0.8 1.0 0.7 0.5 1.2 0.9 6.4 1.1 0.0 2.2 1.5 0.7 22.6 1.2 0.0 0.5 0.3 0.2 0.0 9.8 0.0 0.0 0.3 0.3 0.6 0.0 4.6 8.3 11.5 2.8 0.2 0.0 0.0 0.0 0.9 0.1 0.1 0.0 29.4 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.0 0.0 4.8 3.8 0.0 30.6 0.0 5.6 0.0 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.4 0.3 0.0 0.0 1.9 0.0 0.0 0.0 1.1 0.1 0.1 9.4 1.0 0.0 0.4 0.1 0.2 2.4 IL1B "IL-1B, IL1-BETA, IL1F2" ENSG00000125538 "Interleukin 1 beta" P01584 2 112829751-112836816 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 201.7;urinary bladder: 126.2" "Group enriched" "Detected in many" 11 "Langerhans cells: 1451.9;Macrophages: 1510.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 94.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.1" "Cell line enhanced" "Detected in many" "BJ hTERT+: 649.3;HBEC3-KT: 293.3;HMC-1: 235.1;hTEC/SVTERT24-B: 319.1;hTERT-RPE1: 277.0;U-87 MG: 571.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 2330 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "unprognostic (1.55e-3)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.75e-2)" "unprognostic (5.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.12e-2)" "unprognostic (2.63e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-1)" "unprognostic (3.63e-3)" "unprognostic (3.72e-2)" "unprognostic (5.57e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (1.29e-2)" "unprognostic (4.42e-2)" "unprognostic (5.09e-2)" "unprognostic (4.01e-2)" 43.9 7.6 2.5 53.6 2.2 201.7 2.0 3.1 4.6 3.7 4.2 8.1 3.0 7.4 2.0 3.4 4.1 19.0 3.3 2.3 3.4 7.7 9.1 17.4 9.5 4.8 4.6 0.8 4.4 3.0 2.6 7.8 3.8 6.1 6.5 0.3 3.8 1.8 0.1 0.7 3.5 9.2 4.4 17.8 25.5 1.1 2.8 9.4 2.6 7.0 12.8 126.2 1.0 6.6 6.3 0.1 0.2 0.0 0.4 0.0 0.0 2.1 649.3 3.1 6.5 0.0 0.0 0.0 18.0 0.5 11.3 14.7 0.0 293.3 39.2 0.0 0.0 29.5 0.4 0.0 2.2 0.0 235.1 1.1 8.9 319.1 103.5 277.0 0.0 0.1 0.0 0.8 0.6 0.0 0.0 2.9 0.1 1.2 26.2 1.0 0.0 0.0 0.0 48.2 0.0 0.0 1.7 0.0 2.5 0.0 0.0 2.8 0.0 15.3 0.2 0.7 0.5 0.1 0.0 0.2 571.5 14.0 22.7 1.7 12.3 4.4 0.0 19.5 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 94.1 0.2 7.7 0.0 0.0 3.4 2.5 2.2 3.1 4.6 2.3 3.4 4.8 4.6 3.8 4.4 2.8 6.6 23.8 9.6 28.2 0.0 14.1 30.8 5.4 25.4 0.0 0.2 8.2 13.3 4.8 0.0 16.2 1.8 0.0 1.5 7.5 2.8 0.0 33.2 0.3 4.9 5.0 20.0 0.0 58.9 0.0 0.6 2.6 8.1 44.4 8.4 41.7 0.0 1.4 0.4 108.1 0.0 0.0 12.7 14.2 130.5 1451.9 0.7 0.0 1510.7 23.2 1.9 7.9 0.3 0.0 0.0 0.0 2.9 10.0 0.0 9.3 4.7 0.2 0.7 8.6 0.3 0.0 1.5 4.3 0.0 0.4 8.3 20.3 4.4 6.3 0.0 1.9 6.1 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 495.7;Kupffer cells: 207.9;Langerhans cells: 1083.3;Macrophages: 210.8;Pancreatic endocrine cells: 211.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 6.4;pons: 1.9" "Immune cell enriched" "Detected in some" 26 "neutrophil: 377.5" "Lineage enriched" "Detected in many" 26 "granulocytes: 377.5" "Cell line enriched" "Detected in some" 8 "HDLM-2: 469.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" NA NA 7130000 27000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" 19.7 5.9 0.2 35.5 0.7 52.8 3.7 0.3 6.4 10.3 1.9 29.7 0.8 2.5 3.5 41.2 17.7 5.3 4.0 0.2 0.5 16.0 11.6 30.8 3.3 0.5 0.4 1.2 3.7 0.3 0.8 20.1 1.9 2.3 43.7 0.1 7.9 2.2 1.2 30.7 4.6 3.4 0.3 90.1 33.0 0.5 0.7 7.4 1.9 2.9 38.5 6.2 20.5 0.3 7.3 0.9 0.0 0.0 0.9 1.2 0.8 0.0 0.2 0.0 0.1 7.7 0.2 0.1 14.7 0.0 0.3 2.9 0.0 0.5 0.0 469.8 0.4 0.1 0.1 4.0 2.5 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 60.4 0.0 0.0 0.0 0.0 24.0 1.7 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.4 0.0 1.1 0.4 7.2 0.2 0.0 0.3 0.0 0.5 0.2 0.0 0.1 4.3 0.0 0.0 2.3 0.0 0.0 0.9 0.0 14.5 0.0 0.0 0.0 377.5 0.2 0.1 0.2 5.9 1.5 0.2 0.7 0.3 6.4 0.2 0.5 0.5 0.4 1.9 0.3 0.7 0.3 1.2 6.4 1.1 0.0 1.7 147.9 13.5 2.0 495.7 0.0 0.5 0.4 0.6 10.0 0.3 1.8 0.0 1.2 1.2 23.8 5.9 15.0 2.8 14.5 1.5 4.4 6.7 2.7 0.0 8.3 36.3 6.1 18.3 8.0 2.5 0.0 3.6 16.2 5.8 0.0 0.0 117.4 0.0 207.9 1083.3 4.0 0.3 210.8 32.0 0.0 3.5 0.0 0.0 0.0 0.0 211.0 26.8 0.0 1.6 20.4 0.0 0.7 2.2 0.0 6.6 0.7 3.8 0.7 2.2 38.1 84.0 27.8 2.7 0.4 26.8 14.4 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IL2 "IL-2, TCGF" ENSG00000109471 "Interleukin 2" P60568 4 122451470-122456725 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Cytokine, Growth factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Melanocytes: 3.6;T-cells: 13.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010310 Uncertain "Secreted to blood" NA NA 20300 "Cluster 7: Non-specific - Mitochondria" "CAB010310: AB_649346" "unprognostic (8.87e-5)" "unprognostic (6.13e-3)" "unprognostic (1.38e-3)" "unprognostic (9.79e-3)" "unprognostic (2.56e-2)" "unprognostic (7.32e-2)" "unprognostic (2.06e-5)" "unprognostic (5.21e-3)" "unprognostic (8.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 13.4 0.0 0.0 0.0 IL21R CD360 ENSG00000103522 "Interleukin 21 receptor" Q9HBE5 16 27402174-27452042 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 7.6;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "B-cells: 15.5;dendritic cells: 21.8;Langerhans cells: 11.4;NK-cells: 23.7;Plasma cells: 13.4;T-cells: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 25.9;HDLM-2: 110.8;Karpas-707: 49.3;RH-30: 37.2;RPMI-8226: 63.0;U-266/70: 24.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042296 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA042296: AB_10806236" "unprognostic (2.91e-2)" "unprognostic (2.65e-3)" "unprognostic (6.64e-4)" "unprognostic (1.58e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.29e-4)" "unprognostic (8.33e-2)" "unprognostic (2.06e-1)" "unprognostic (8.50e-6)" "unprognostic (2.26e-2)" "unprognostic (1.13e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-10)" "unprognostic (8.79e-2)" "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.58e-2)" 0.5 0.4 1.4 11.9 1.0 7.6 0.2 1.1 2.6 0.2 0.9 0.8 0.6 0.3 0.2 0.3 0.2 1.1 0.7 0.9 2.3 0.9 0.4 2.9 24.7 2.1 2.3 0.2 0.3 0.0 0.5 0.8 3.3 0.4 0.9 1.1 0.6 0.1 0.3 0.8 2.1 0.7 1.2 5.5 1.5 1.1 1.2 14.4 0.6 0.0 18.8 2.2 0.2 1.6 0.1 0.2 0.3 0.2 0.0 1.3 0.8 0.8 0.1 0.1 2.2 0.2 0.2 25.9 0.2 2.1 1.4 0.1 0.0 0.1 0.1 110.8 0.1 5.4 0.2 0.7 3.4 0.2 1.5 3.8 0.0 6.8 0.1 0.7 0.0 0.6 0.3 49.3 3.8 0.2 0.1 0.5 0.9 0.1 0.0 0.4 37.2 63.0 0.0 0.1 0.2 0.2 0.1 0.1 2.7 0.2 0.1 1.3 2.8 1.9 0.7 0.6 0.2 24.7 9.4 5.9 5.2 1.4 0.2 0.5 0.4 0.1 13.4 8.3 4.9 1.8 8.6 14.2 2.3 14.2 9.2 9.3 0.9 9.5 27.0 1.1 10.8 7.3 1.4 1.0 1.1 2.6 0.9 2.3 2.1 2.3 3.3 1.2 1.2 1.6 0.2 0.0 1.3 0.0 15.5 0.4 0.1 0.0 0.0 2.0 0.2 0.1 1.9 0.0 0.0 0.0 4.2 0.1 21.8 0.1 0.0 0.0 6.5 0.1 0.2 0.9 0.0 0.0 0.4 0.0 0.1 0.3 1.5 0.2 0.0 0.0 1.1 0.2 8.2 0.0 0.5 0.0 0.0 5.0 11.4 5.7 0.0 3.6 1.8 2.8 1.8 0.2 23.7 0.5 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.2 0.0 0.5 0.0 0.8 0.8 0.2 0.0 0.0 0.9 0.1 25.1 0.1 0.1 0.1 IL24 "C49A, FISP, IL-24, IL10B, mda-7, Mob-5, ST16" ENSG00000162892 "Interleukin 24" Q13007 1 206897443-206904139 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.2;lymphoid tissue: 25.5;urinary bladder: 14.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.8;Basal prostatic cells: 2.9;Fibroblasts: 11.6;Smooth muscle cells: 7.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 9.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 5.4;T-cells: 3.6" "Cell line enriched" "Detected in some" 9 "BJ hTERT+: 172.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB025972 Uncertain "Secreted to blood" NA NA 140000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB025972: " "prognostic favorable (5.09e-4)" "unprognostic (3.79e-1)" "unprognostic (2.89e-2)" "unprognostic (4.09e-3)" "unprognostic (3.98e-1)" "unprognostic (2.68e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-2)" "unprognostic (3.98e-1)" "unprognostic (3.35e-2)" "unprognostic (8.04e-2)" "unprognostic (7.63e-2)" "unprognostic (3.43e-4)" "unprognostic (5.41e-2)" "unprognostic (1.29e-1)" "unprognostic (7.91e-2)" "unprognostic (3.33e-2)" 3.5 0.1 0.1 3.6 0.1 1.5 0.7 0.1 0.2 0.4 0.2 1.3 0.0 1.0 0.0 0.9 1.0 1.3 0.8 0.1 0.3 0.8 1.2 1.8 5.8 0.2 0.4 0.2 0.2 0.0 0.5 0.9 0.3 1.0 0.0 0.0 1.1 0.0 3.8 0.2 15.2 0.1 0.1 25.5 0.6 0.1 0.3 0.0 1.0 0.0 0.2 14.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 172.7 0.0 0.4 0.0 0.5 0.2 0.1 0.0 3.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.2 2.5 18.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 16.7 0.7 0.0 0.0 0.0 2.3 1.2 7.4 0.5 2.5 0.8 0.3 1.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 1.9 5.4 1.7 2.7 0.0 5.0 3.6 2.9 0.4 0.4 0.0 0.0 1.9 0.8 0.1 0.1 0.1 0.2 0.1 0.3 0.2 0.4 0.3 0.1 0.3 0.1 0.2 0.0 1.3 0.0 1.8 6.8 2.9 0.5 0.0 0.0 0.4 0.3 1.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.1 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 7.9 0.0 0.0 0.0 1.3 0.0 0.6 0.0 0.1 0.7 IL2RA "CD25, IDDM10, IL2R" ENSG00000134460 "Interleukin 2 receptor subunit alpha" P01589 10 6010689-6062370 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.9;lymphoid tissue: 17.4;urinary bladder: 11.2" "Group enriched" "Detected in some" 6 "granulocytes: 80.8;monocytes: 177.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "basophil: 175.9;T-reg: 248.0" "Group enriched" "Detected in many" 14 "granulocytes: 175.9;T-cells: 248.0" "Cell line enriched" "Detected in some" 59 "HDLM-2: 1113.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002419, HPA054622" Enhanced NA NA 410000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB002419: AB_563538, HPA054622: AB_2682546" "unprognostic (2.82e-1)" "unprognostic (8.10e-3)" "unprognostic (1.75e-2)" "unprognostic (5.86e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-3)" "unprognostic (2.78e-2)" "unprognostic (2.73e-1)" "unprognostic (5.03e-2)" "unprognostic (6.32e-2)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.08e-9)" "unprognostic (2.10e-2)" "unprognostic (4.66e-2)" "unprognostic (2.22e-1)" "unprognostic (5.10e-2)" 18.9 1.9 0.0 14.2 0.0 0.4 1.4 0.1 0.2 0.5 1.1 3.3 1.9 0.5 0.2 2.6 0.3 2.9 0.8 0.1 0.1 0.7 0.5 2.4 17.4 0.5 0.1 0.1 0.5 0.3 0.9 2.5 0.4 0.4 2.1 0.0 0.5 0.8 0.1 0.4 6.5 4.7 0.1 7.5 1.2 0.2 0.2 5.2 1.3 0.6 12.9 11.2 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1113.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.9 0.0 0.4 18.9 0.0 0.3 0.0 175.9 0.1 20.1 0.6 0.0 2.2 14.7 27.3 3.1 0.2 7.3 2.0 0.2 0.9 13.4 0.3 0.2 248.0 3.2 0.0 0.0 0.1 0.2 0.1 0.1 0.5 0.1 0.4 0.1 0.2 0.2 0.4 0.0 1.8 1.0 13.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.0 0.0 0.0 8.3 0.0 0.0 0.1 0.2 0.2 0.6 0.4 0.0 0.8 0.2 0.6 0.0 0.7 1.1 0.1 80.8 0.0 0.4 0.2 0.3 0.0 0.2 0.0 0.0 7.7 4.8 0.1 0.0 19.3 3.6 1.9 177.6 0.0 2.1 0.0 0.3 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.1 0.6 0.0 19.6 0.0 0.1 0.2 IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Cell type enhanced" "Detected in many" "dendritic cells: 130.1;Extravillous trophoblasts: 85.5;NK-cells: 388.3;T-cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cell line enriched" "Detected in some" 8 "HDLM-2: 525.8" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" 3.2 1.3 2.0 22.4 1.6 36.8 1.9 0.8 2.3 2.2 1.5 5.1 5.5 7.6 2.9 3.5 2.9 6.8 1.9 2.2 1.0 1.0 8.5 12.4 35.7 2.4 2.2 1.6 0.8 0.4 0.6 36.3 1.9 2.3 5.2 0.0 4.3 3.2 0.7 8.9 8.3 2.5 1.7 50.2 6.4 1.5 3.3 14.9 1.8 0.7 24.0 8.0 1.0 1.8 0.4 0.0 1.0 0.0 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 525.8 0.6 1.0 0.0 0.1 0.0 0.0 24.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.7 0.1 4.2 3.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.6 2.3 0.0 0.9 0.0 0.0 13.2 0.0 0.6 36.2 66.0 0.1 0.4 0.4 0.5 5.4 0.1 0.5 50.8 0.6 27.4 0.4 11.4 28.6 0.1 1.9 3.6 15.0 1.2 186.4 0.5 0.3 24.4 37.3 2.0 1.6 0.8 2.3 2.2 1.0 2.4 2.2 1.9 1.7 3.3 1.8 1.5 3.2 6.8 0.0 3.6 3.2 0.7 0.1 5.7 0.0 1.0 0.8 1.7 0.0 0.6 1.8 0.0 0.6 130.1 0.2 0.0 0.3 2.2 0.5 1.2 1.0 0.0 16.8 0.1 0.2 85.5 1.4 5.6 1.2 10.1 0.1 7.1 1.8 2.3 0.0 0.1 0.1 0.0 5.3 1.7 1.6 0.3 3.7 5.4 0.0 2.0 0.0 388.3 0.0 0.1 0.0 0.0 0.0 18.6 0.2 0.1 0.2 0.7 0.0 0.0 0.2 0.9 0.0 0.3 0.5 1.6 1.2 103.6 0.0 0.3 0.1 IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 186.1;dendritic cells: 199.0;Distal enterocytes: 202.0;NK-cells: 310.0;Paneth cells: 133.2;Plasma cells: 221.2;T-cells: 289.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "Karpas-707: 2316.2" "HPA046641, HPA049691" Enhanced Approved Vesicles NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" Vesicles "HPA046641: AB_2679733, HPA049691: AB_2680851" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" 12.8 6.2 2.7 132.2 2.4 87.3 14.1 2.5 6.3 10.2 4.0 98.9 50.4 7.5 7.5 15.1 6.8 28.2 4.6 2.3 2.8 7.1 20.6 51.7 235.6 3.6 2.7 4.9 4.1 1.9 1.5 16.9 4.2 7.8 118.0 0.5 19.0 5.9 2.6 15.4 82.8 12.3 3.1 119.4 41.4 2.2 3.0 346.4 5.8 6.3 306.9 46.4 5.5 3.8 1.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 4.7 9.1 187.3 13.5 0.0 0.7 1.7 0.4 0.0 0.0 160.3 0.2 23.6 0.3 0.3 0.2 99.3 4.0 0.0 0.0 0.0 0.1 0.1 0.0 220.5 43.3 2316.2 0.0 0.0 356.4 193.7 0.4 0.9 0.1 79.5 0.8 20.0 0.0 0.7 0.2 0.3 2.3 0.1 0.5 0.0 0.0 3.5 0.4 0.0 1.0 0.0 0.5 132.1 242.2 119.6 2.1 397.4 0.9 540.5 102.2 169.7 1204.7 239.5 1179.9 604.7 1086.3 1250.7 243.5 603.0 742.0 943.1 773.0 1190.3 177.0 368.9 1422.2 1494.0 2.7 2.4 2.5 6.3 2.3 2.8 3.6 2.7 4.2 3.1 3.0 3.8 3.3 3.2 11.2 0.0 186.1 8.2 8.1 13.1 1.2 0.0 1.5 1.7 0.9 4.3 4.2 0.0 0.0 0.5 199.0 202.0 0.0 1.2 0.1 0.8 0.7 5.8 77.7 27.1 0.0 2.3 0.3 4.2 13.7 0.7 39.3 0.4 6.1 2.1 31.1 0.0 0.0 24.5 4.1 25.2 116.7 0.0 0.0 45.4 42.7 1.0 91.1 0.1 310.0 0.0 0.1 28.0 133.2 0.4 221.2 4.3 88.8 1.1 2.3 0.4 0.0 1.3 2.6 0.0 0.1 1.8 6.8 0.3 289.5 0.0 18.6 8.9 IL4 "BCGF-1, BCGF1, BSF1, IL-4, MGC79402" ENSG00000113520 "Interleukin 4" P05112 5 132673986-132682678 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "B-cell activation" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "T-cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 861 "basophil: 474.9" "Lineage enriched" "Detected in single" 861 "granulocytes: 474.9" "Cell line enriched" "Detected in some" 5 "MOLT-4: 21.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA072995, CAB078477" Approved "Secreted to blood" NA NA 13600 "Cluster 38: Basophils - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB078477: AB_417057, HPA072995: AB_2732215" "unprognostic (3.40e-2)" "unprognostic (9.19e-2)" "unprognostic (1.41e-1)" "unprognostic (2.49e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.69e-1)" "unprognostic (7.33e-2)" "unprognostic (2.26e-2)" "unprognostic (1.96e-1)" "unprognostic (1.47e-10)" "unprognostic (9.21e-3)" "unprognostic (2.88e-1)" "unprognostic (4.93e-2)" "unprognostic (1.24e-2)" 0.1 0.3 0.1 0.4 0.1 0.3 0.1 0.5 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.2 0.3 0.0 0.1 0.2 0.0 0.0 0.3 0.3 0.3 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.0 0.5 0.3 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 474.9 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.5 0.3 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 IL5 "EDF, IL-5, TRF" ENSG00000113525 "Interleukin 5" P05113 5 132541445-132556838 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;testis: 5.1" "Cell type enriched" "Detected in some" 7 "Spermatocytes: 19.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 1.4" "Lineage enriched" "Detected in single" 8 "B-cells: 1.4" "Cell line enhanced" "Detected in some" "Hep G2: 2.8;TIME: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB010304 Approved "Secreted to blood" NA NA 4130 "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB010304: AB_2296159" "unprognostic (1.66e-1)" "unprognostic (4.76e-2)" "unprognostic (5.30e-3)" "unprognostic (2.35e-1)" "unprognostic (9.07e-2)" "unprognostic (7.98e-2)" "unprognostic (2.03e-2)" "unprognostic (3.51e-2)" "unprognostic (1.97e-1)" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (2.09e-1)" "unprognostic (5.27e-2)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" 0.1 0.0 0.8 0.1 0.3 0.0 0.0 1.7 1.2 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.2 1.5 0.3 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.0 0.2 5.1 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 0.3 0.1 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 1.7 1.2 1.5 0.3 0.3 0.1 0.8 0.8 0.5 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.7 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.1 0.0 19.5 1.2 0.0 0.1 0.0 1.6 0.0 0.0 0.0 IL6 "BSF2, HGF, HSF, IFNB2, IL-6" ENSG00000136244 "Interleukin 6" P05231 7 22725884-22732002 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 217.6;urinary bladder: 281.3" "Group enriched" "Detected in many" 4 "Adipocytes: 188.5;Endometrial ciliated cells: 163.9;Endothelial cells: 287.4;Fibroblasts: 593.3;Glandular and luminal cells: 322.2;Smooth muscle cells: 449.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 44 "memory B-cell: 3.9;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 48 "B-cells: 4.8" "Group enriched" "Detected in many" 4 "BJ hTERT+: 2214.7;GAMG: 1447.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB023406, CAB072821" Supported Approved Vesicles "Secreted to blood" NA NA 5700 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB023406: AB_617317, CAB072821: " "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (3.59e-2)" "unprognostic (9.88e-3)" "unprognostic (1.35e-1)" "unprognostic (3.07e-3)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.10e-11)" "unprognostic (2.45e-3)" "unprognostic (2.10e-1)" "unprognostic (4.31e-2)" "unprognostic (7.80e-2)" 217.6 13.9 3.6 30.8 3.8 46.8 31.3 3.7 6.0 4.7 9.2 22.1 1.9 5.7 0.0 34.9 18.9 41.6 55.1 3.8 3.8 17.7 13.0 114.9 9.1 4.0 4.3 6.2 19.5 10.0 38.3 11.3 4.9 16.5 17.3 1.4 12.0 2.0 7.8 7.6 8.3 19.5 3.9 7.0 18.0 1.2 4.7 6.3 14.2 4.1 3.7 281.3 5.7 4.1 0.1 0.0 0.0 0.0 0.7 2.2 7.5 8.9 2214.7 43.2 151.0 0.0 0.6 0.2 71.6 15.2 1447.6 1.7 0.0 0.3 59.9 94.2 0.2 0.0 3.7 0.0 47.3 0.0 0.6 5.6 0.0 413.8 63.1 44.2 18.2 0.0 10.6 0.5 1.9 0.1 0.0 0.3 1.6 0.7 0.5 0.0 0.0 0.0 124.2 0.0 0.0 0.0 144.5 0.1 0.6 7.9 0.1 0.1 14.5 15.2 1.4 28.2 4.7 0.0 27.8 0.4 98.5 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 3.8 3.7 6.0 3.8 3.8 4.0 4.3 4.9 3.9 4.7 4.1 188.5 6.4 22.7 0.0 27.0 44.6 3.4 28.5 1.8 0.1 1.4 1.1 1.4 0.0 17.7 3.7 0.0 1.1 0.4 0.1 0.0 9.8 0.4 163.9 44.6 287.4 0.0 0.0 0.0 2.8 4.0 593.3 0.0 322.2 6.3 0.0 3.6 0.1 4.1 0.0 0.0 0.0 0.0 9.3 76.5 0.2 0.0 27.4 40.9 2.8 4.2 0.0 0.0 0.0 0.1 4.3 0.1 0.0 0.9 16.4 0.0 0.0 8.1 0.0 0.0 28.9 449.0 0.0 0.1 0.4 33.4 1.4 8.6 0.2 0.0 20.6 IL6R CD126 ENSG00000160712 "Interleukin 6 receptor" P08887 1 154405193-154469450 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 58.3;skeletal muscle: 94.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.4;Hepatocytes: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 88.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 224.4;U-266/84: 274.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 24800000 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 41: Macrophages - Immune response" "unprognostic (1.19e-1)" "unprognostic (3.97e-1)" "unprognostic (1.19e-1)" "unprognostic (1.08e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-2)" "unprognostic (3.27e-1)" "unprognostic (6.42e-2)" "prognostic favorable (1.65e-4)" "unprognostic (7.94e-2)" "unprognostic (1.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" 11.0 5.8 6.8 25.5 8.0 16.6 5.9 7.4 11.3 7.6 4.8 14.7 15.6 8.4 2.5 7.4 12.4 9.0 6.6 6.2 6.4 14.2 58.3 16.3 27.3 10.9 8.8 8.9 8.7 1.2 8.9 6.6 9.8 6.0 9.8 1.4 3.3 2.9 94.2 6.4 19.8 8.8 10.4 19.8 10.2 3.4 10.6 9.3 2.7 26.4 22.4 9.3 5.3 10.4 3.3 5.8 0.4 0.4 3.4 5.1 0.4 3.3 2.5 2.0 1.0 0.6 3.9 0.2 7.4 4.1 12.0 1.7 1.1 17.8 1.6 62.6 1.9 0.8 2.2 13.9 0.5 9.6 5.0 3.0 10.5 1.7 26.1 0.6 2.6 0.1 0.7 24.0 0.6 1.4 0.2 16.0 1.8 1.1 13.5 0.3 0.3 53.6 10.9 4.5 0.5 0.3 1.1 36.2 59.5 4.5 3.3 224.4 2.5 3.5 3.4 3.3 2.2 43.1 274.1 0.4 4.4 61.0 5.7 7.5 29.4 28.1 0.6 18.0 1.5 1.5 15.2 1.6 36.1 0.6 14.9 5.4 88.2 1.3 8.0 13.1 21.2 15.8 6.8 8.0 7.4 11.3 6.2 6.4 10.9 8.8 9.8 10.4 10.6 10.4 3.4 115.4 82.7 18.6 11.0 37.9 72.9 8.3 13.1 0.1 7.5 7.4 9.9 25.8 33.9 1.8 0.0 0.5 16.9 38.5 0.0 4.3 35.1 34.1 5.7 10.9 7.7 3.8 5.7 1.2 1.2 26.3 25.5 48.7 61.3 1.3 3.9 108.6 42.9 0.0 5.9 6.5 14.2 41.8 79.3 14.5 0.3 63.7 24.9 44.0 76.8 3.8 4.1 3.0 3.3 7.5 8.7 0.4 41.9 58.9 60.1 15.5 29.0 0.2 0.0 28.3 19.2 0.4 1.1 7.2 29.7 1.0 17.1 0.1 15.4 17.0 IL6ST "CD130, GP130, sGP130" ENSG00000134352 "Interleukin 6 signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 580.3;Hepatic stellate cells: 808.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 16.7" "Lineage enriched" "Detected in many" 4 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 151.3;BJ hTERT+: 175.2;HHSteC: 155.1;HSkMC: 135.1;TIME: 147.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 160000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" 67.1 46.0 26.8 14.1 31.0 9.6 51.3 30.9 36.7 43.0 21.3 33.9 4.2 35.2 18.5 18.4 34.2 23.6 35.1 23.5 31.4 30.0 77.6 53.3 15.9 32.1 27.0 36.9 21.9 39.6 22.5 101.7 35.9 32.6 14.3 28.6 31.9 29.9 41.0 17.8 31.1 28.7 35.1 34.7 27.8 8.9 25.3 23.6 40.4 34.7 16.2 37.7 35.1 42.9 14.4 35.6 9.4 18.8 75.5 151.3 22.3 54.5 175.2 44.1 62.4 40.5 16.3 1.1 33.7 52.5 71.6 7.8 9.8 19.2 84.1 1.6 8.5 4.6 20.1 14.2 155.1 0.4 6.2 135.1 11.1 103.1 42.7 43.6 101.8 1.9 3.7 51.0 47.0 2.9 0.7 0.8 1.5 1.8 10.1 1.1 22.5 14.4 22.5 12.1 3.8 5.9 26.6 5.7 19.7 13.7 29.5 3.1 147.8 12.4 10.1 44.5 24.6 14.6 8.2 0.5 28.9 1.1 31.1 0.0 3.9 0.1 0.7 3.4 0.3 0.8 3.7 0.8 2.1 0.4 16.7 4.8 0.6 0.8 0.5 1.9 4.1 4.0 26.8 31.0 30.9 36.7 23.5 31.4 32.1 27.0 35.9 35.1 25.3 42.9 221.6 134.6 149.8 59.4 30.0 103.9 98.0 60.6 71.2 56.5 202.4 81.3 81.5 124.4 105.4 68.0 35.5 77.9 33.1 34.5 7.9 85.3 12.3 76.4 227.6 256.2 19.8 41.1 25.7 62.0 75.5 285.5 59.1 580.3 32.9 58.6 808.5 219.8 56.0 16.8 70.0 34.1 46.8 93.7 99.1 16.7 105.9 60.3 80.0 188.3 45.8 190.8 7.2 75.4 64.2 80.8 35.6 130.5 100.6 163.9 33.6 52.2 80.3 39.3 98.6 158.7 150.3 54.4 38.6 44.9 83.5 101.8 75.5 228.7 17.1 106.1 IL7 IL-7 ENSG00000104432 "Interleukin 7" P13232 8 78675743-78805523 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 108.8;Late spermatids: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.7;naive B-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;HDLM-2: 15.4;HEL: 18.2;HMC-1: 25.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019590 Approved "Secreted to blood" NA NA 60700 "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA019590: AB_10794621" "unprognostic (3.19e-3)" "unprognostic (1.44e-1)" "unprognostic (9.57e-3)" "unprognostic (5.45e-2)" "unprognostic (9.37e-3)" "unprognostic (3.36e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (6.55e-2)" "unprognostic (2.11e-4)" 2.3 1.2 0.2 4.1 0.3 2.1 1.5 0.4 0.2 2.3 0.3 5.1 6.7 1.1 0.3 3.5 4.8 3.1 0.6 0.3 0.5 1.4 4.2 3.3 8.7 0.6 0.4 0.9 1.0 0.0 0.5 0.3 0.5 1.8 4.4 0.7 1.1 0.9 0.1 8.8 8.7 1.1 0.4 3.5 3.8 1.7 1.2 0.8 1.3 0.1 4.2 2.8 1.5 0.2 0.3 0.0 0.1 0.0 0.4 0.4 0.0 1.4 1.4 1.3 1.9 0.0 7.6 0.1 0.0 4.4 4.5 4.2 0.1 0.0 0.0 15.4 0.0 18.2 0.6 2.1 0.1 0.1 25.4 1.3 0.0 0.2 0.6 4.9 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.1 0.0 5.4 3.2 0.0 2.4 2.6 0.3 0.2 0.0 0.1 0.0 0.2 0.8 0.9 0.0 2.0 0.3 0.0 0.0 3.4 0.0 1.9 5.2 0.3 0.0 0.4 0.2 0.0 9.7 1.0 1.0 2.2 8.7 0.2 0.3 0.0 0.5 0.8 0.3 7.3 0.6 0.2 0.3 0.4 0.2 0.3 0.5 0.6 0.4 0.5 0.4 1.2 0.2 0.6 0.0 3.6 5.9 12.2 6.0 3.2 1.2 10.8 0.1 1.3 0.9 0.7 5.7 2.4 1.8 0.0 0.0 1.3 7.8 9.8 1.2 108.8 22.9 0.8 4.9 3.0 10.5 16.0 5.1 0.0 2.5 11.2 0.6 0.0 0.1 1.8 2.4 0.9 0.0 11.0 6.2 2.0 1.0 3.3 145.5 0.6 1.9 0.0 1.0 3.4 2.0 0.0 20.1 6.0 2.6 11.5 1.2 1.0 1.2 12.4 9.5 24.2 0.4 0.0 2.2 0.5 2.3 0.9 5.2 6.5 0.0 1.6 0.1 4.6 1.7 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 IL9 "HP40, IL-9, P40" ENSG00000145839 "Interleukin 9" P15248 5 135892246-135895841 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 279 "HDLM-2: 43.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 11000 "Cluster 44: HDLM-2 - Immune response" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ILF3 "DRBP76, MPHOSPH4, MPP4, MPP4110, NF110, NF110b, NF90, NF90a, NF90c, NF90ctv, NFAR-1, NFAR-2, NFAR110, NFAR90, TCP110" ENSG00000129351 "Interleukin enhancer binding factor 3" Q12906 19 10654261-10692417 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001897 Supported Enhanced Nucleoplasm,Nucleoli,Mitochondria No No 1600000 "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Mitochondria" "HPA001897: AB_1078703" "unprognostic (2.39e-1)" "unprognostic (9.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (5.55e-3)" "unprognostic (1.11e-3)" "unprognostic (2.96e-1)" "prognostic unfavorable (1.57e-4)" "unprognostic (3.45e-2)" "unprognostic (1.04e-1)" "unprognostic (4.38e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (7.57e-3)" "unprognostic (7.61e-2)" "unprognostic (1.03e-1)" "unprognostic (6.20e-2)" 49.2 58.5 31.6 79.4 31.5 179.5 49.8 44.2 37.5 60.8 38.5 56.0 52.0 64.5 40.9 60.4 61.1 31.9 49.0 31.4 37.9 43.1 32.1 50.5 82.9 30.6 32.8 76.5 52.6 55.5 53.8 47.8 29.7 52.4 44.8 69.5 54.0 48.8 83.6 58.7 56.1 49.8 29.4 61.7 47.8 78.9 35.4 97.3 61.6 58.2 72.3 56.1 52.1 42.8 285.9 226.7 359.5 330.9 76.5 104.0 208.9 178.1 149.6 291.8 226.5 261.8 160.8 353.2 172.1 160.8 178.0 248.9 392.5 240.7 260.9 227.2 349.5 459.3 206.9 247.5 109.2 334.8 219.5 99.0 105.0 232.1 257.4 111.1 253.1 201.7 400.0 269.4 172.3 233.8 558.1 534.0 433.3 149.2 246.2 405.2 342.2 244.2 116.3 297.1 395.1 286.7 229.0 179.4 131.6 161.6 152.2 212.0 205.2 237.6 224.2 249.3 356.5 228.9 339.7 431.4 132.8 351.6 262.2 20.2 18.1 10.2 24.4 14.1 20.6 19.3 20.2 22.3 22.8 22.9 19.5 20.2 2.7 21.3 21.2 25.1 20.6 11.8 31.6 31.5 44.2 37.5 31.4 37.9 30.6 32.8 29.7 29.4 35.4 42.8 63.6 99.3 133.9 34.3 106.2 86.2 110.0 64.2 104.7 95.4 77.5 64.3 69.7 60.1 98.8 42.3 85.5 90.0 100.0 78.4 27.4 89.0 21.2 89.8 105.7 77.4 114.0 124.3 24.4 80.4 111.1 94.8 101.9 121.4 96.8 145.9 36.8 47.9 71.4 94.2 34.0 85.6 50.8 55.0 68.3 21.0 76.4 75.8 39.2 24.4 66.0 69.2 92.7 31.7 28.9 88.2 55.6 62.4 124.9 144.6 38.8 47.2 82.9 103.6 32.9 100.3 80.1 137.2 120.6 113.8 77.0 70.9 103.5 140.8 111.7 94.9 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 ING1 "p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a" ENSG00000153487 "Inhibitor of growth family member 1" Q9UK53 13 110712736-110723339 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 212.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016136, CAB017773, HPA052591" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "CAB016136: AB_628077, CAB017773: , HPA052591: AB_2681876" "unprognostic (1.14e-2)" "unprognostic (3.25e-2)" "unprognostic (3.51e-2)" "prognostic favorable (5.81e-4)" "unprognostic (4.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.36e-1)" "unprognostic (1.87e-1)" "unprognostic (9.43e-2)" "unprognostic (2.27e-1)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (7.05e-3)" "unprognostic (6.78e-2)" "unprognostic (2.40e-3)" 13.7 7.3 5.9 8.6 6.2 20.2 10.2 6.5 10.2 10.6 5.9 13.4 9.7 12.6 5.3 8.3 14.4 6.7 9.1 6.6 6.7 9.5 18.6 12.8 9.7 7.2 6.2 22.4 8.2 3.1 9.4 7.7 6.4 11.2 4.3 6.7 9.9 4.9 11.7 9.4 12.2 4.8 6.0 14.4 10.0 31.5 6.4 13.0 7.6 9.5 6.3 10.1 9.4 8.0 28.8 11.1 19.8 19.0 9.1 6.1 19.7 14.5 12.1 9.2 11.1 21.5 19.9 18.4 22.9 5.7 14.3 17.8 8.0 7.2 7.7 34.8 15.3 16.3 16.2 16.2 5.2 21.7 15.2 5.6 7.4 8.0 4.8 7.2 6.5 19.6 15.3 15.0 6.0 16.5 37.7 24.9 19.4 17.9 9.3 27.0 10.0 10.4 8.1 14.5 19.4 20.9 14.2 28.3 20.7 6.8 9.5 25.3 9.8 11.3 13.9 11.9 16.5 18.0 19.5 24.0 18.9 17.6 18.8 38.5 4.5 18.0 15.9 5.6 16.7 23.4 13.2 14.2 4.3 27.5 13.5 11.2 6.2 20.4 6.5 4.7 18.8 9.4 5.9 6.2 6.5 10.2 6.6 6.7 7.2 6.2 6.4 6.0 6.4 8.0 87.2 9.6 18.8 5.9 34.5 36.3 15.4 17.0 54.7 16.7 49.8 88.9 27.0 12.8 11.1 7.3 14.6 14.3 32.0 31.5 7.9 11.7 212.5 51.6 58.5 28.6 12.5 12.6 4.4 6.9 78.8 36.1 27.5 55.7 2.5 20.1 11.0 27.4 17.3 3.3 3.8 31.6 12.2 18.2 23.8 45.8 9.3 29.3 17.8 1.9 14.2 17.8 21.6 2.0 4.3 8.0 18.6 14.7 19.7 22.9 34.2 11.5 21.4 21.1 13.1 70.5 57.7 25.5 17.9 48.8 43.8 15.3 29.6 18.0 24.2 22.4 INHBA ENSG00000122641 "Inhibin subunit beta A" P08476 7 41667168-41705834 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 21.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 94.4;Langerhans cells: 68.0;Leydig cells: 137.6;Smooth muscle cells: 218.3;Syncytiotrophoblasts: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 75.9;hTEC/SVTERT24-B: 227.0;hTERT-HME1: 92.9;hTERT-RPE1: 139.2;TIME: 120.1;U-138 MG: 174.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 210000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (4.11e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (4.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.23e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (7.91e-8)" "unprognostic (6.22e-3)" "unprognostic (1.11e-2)" "unprognostic (3.25e-2)" "unprognostic (3.18e-3)" 2.3 1.5 2.1 5.1 2.0 10.4 0.9 2.3 7.8 1.5 0.7 1.0 0.8 17.3 3.7 2.1 1.2 21.6 5.4 8.7 3.3 2.8 9.5 11.0 1.2 4.3 8.1 6.8 0.6 0.5 0.5 10.9 3.4 3.2 0.6 2.3 5.4 5.0 0.5 2.0 0.5 4.3 4.5 0.5 0.8 1.7 3.0 0.2 1.2 4.6 0.4 10.3 1.1 3.4 4.2 0.0 0.4 0.1 3.3 7.1 0.0 18.2 1.9 9.9 3.3 0.0 0.4 0.0 1.1 6.9 11.6 15.3 0.0 75.9 9.6 5.1 0.0 0.0 0.0 0.0 13.9 0.0 0.2 7.0 4.2 227.0 92.9 139.2 8.2 0.0 0.5 0.0 23.0 0.2 0.0 0.3 1.5 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.1 5.7 11.1 0.6 0.0 6.2 0.1 0.2 120.1 174.7 49.7 18.9 19.0 0.0 0.0 0.0 6.7 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 2.1 2.0 2.3 7.8 8.7 3.3 4.3 8.1 3.4 4.5 3.0 3.4 0.7 3.2 15.7 0.0 0.9 17.3 10.8 13.5 2.2 0.1 3.5 6.5 6.0 0.0 4.4 0.0 0.0 1.4 0.3 0.1 0.0 23.6 0.6 1.4 4.1 5.9 0.0 0.0 2.4 2.0 4.6 42.0 0.0 2.6 7.6 94.4 0.7 18.5 1.5 0.0 0.2 0.2 4.1 1.4 68.0 5.9 137.6 55.8 14.2 0.0 27.0 16.1 0.0 4.0 0.3 11.1 0.1 23.3 0.0 12.5 0.0 0.1 2.8 1.3 0.0 4.9 218.3 0.7 0.3 1.4 8.9 178.4 1.7 18.8 0.2 2.3 INHBB ENSG00000163083 "Inhibin subunit beta B" P09529 2 120346136-120351803 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 52.5;breast: 43.3" "Group enriched" "Detected in many" 7 "Adipocytes: 200.5;Granulosa cells: 653.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 44.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 47.6;ASC diff: 63.1;BJ hTERT+ SV40 Large T+ RasG12V: 38.5;MCF7: 58.4;PC-3: 91.7;SK-BR-3: 163.4;T-47d: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 130000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.80e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.26e-2)" "unprognostic (4.26e-2)" "unprognostic (3.61e-3)" "unprognostic (2.13e-2)" "unprognostic (5.52e-2)" "unprognostic (6.99e-2)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.57e-3)" "unprognostic (4.14e-1)" "prognostic favorable (1.02e-4)" "unprognostic (1.76e-2)" 52.5 3.7 5.6 0.9 5.5 0.2 43.3 8.0 4.0 6.9 3.4 3.4 1.3 7.4 2.6 2.5 6.2 2.5 6.4 3.9 4.8 4.3 20.2 4.4 1.1 9.7 7.4 2.5 4.2 6.3 8.0 1.2 6.0 8.2 0.3 1.0 16.4 0.8 10.4 17.1 2.4 2.2 6.2 0.5 3.6 17.1 7.9 0.4 20.9 2.4 0.7 8.2 6.4 4.2 24.5 47.6 0.2 0.0 63.1 4.9 0.0 3.3 3.8 20.7 38.5 1.0 0.0 0.0 8.3 1.2 0.1 0.1 3.7 0.0 28.9 0.1 0.8 0.0 0.0 1.2 1.0 0.0 0.1 2.6 3.5 0.7 0.0 0.3 0.4 0.0 0.0 0.0 0.1 58.4 0.0 0.1 0.0 4.7 91.7 0.0 0.0 1.2 5.6 0.0 5.4 0.0 0.2 163.4 0.0 0.0 39.2 0.5 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.6 5.5 8.0 4.0 3.9 4.8 9.7 7.4 6.0 6.2 7.9 4.2 200.5 3.2 2.2 8.1 0.2 4.0 2.2 5.5 0.0 0.1 53.7 24.4 0.7 8.6 9.2 1.8 25.0 0.1 0.7 0.1 0.0 0.4 0.6 9.2 1.6 24.3 0.0 2.7 0.1 0.0 0.2 9.8 0.0 12.5 0.0 653.3 24.7 19.4 0.1 0.0 1.3 0.0 8.2 1.3 6.6 3.6 11.8 1.3 1.8 1.0 0.0 0.2 0.0 2.5 0.0 0.2 0.0 6.8 0.3 8.9 0.0 0.0 30.0 0.6 0.0 37.3 3.1 0.8 6.0 0.6 3.0 0.1 0.6 0.2 0.0 3.2 INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239147 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 344.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037601 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Golgi apparatus" "HPA037601: AB_10672281" "unprognostic (2.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.68e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.49e-2)" "unprognostic (3.54e-2)" "unprognostic (1.51e-2)" "unprognostic (1.64e-1)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (2.88e-1)" "unprognostic (1.99e-3)" "unprognostic (2.07e-1)" 45.2 56.4 39.0 34.4 43.4 51.3 44.7 41.3 40.5 63.8 47.3 87.5 35.9 56.1 18.2 34.6 61.3 33.7 73.6 33.2 42.5 60.0 36.6 61.8 36.8 53.9 43.2 68.6 55.7 36.4 60.5 39.7 45.8 68.7 23.3 14.9 53.8 39.5 116.6 31.4 57.1 33.4 45.0 66.1 60.8 24.2 48.8 19.3 67.7 43.0 23.2 59.9 43.4 41.2 28.7 62.1 71.5 49.8 35.4 41.1 122.5 118.9 61.2 80.6 49.6 84.3 72.2 79.5 125.6 101.7 57.8 106.7 60.4 37.6 28.0 101.9 59.1 84.8 344.5 31.9 68.1 56.1 176.7 58.2 39.1 78.0 31.4 100.5 44.2 29.3 59.7 34.7 45.1 78.8 42.1 224.9 67.7 20.7 93.7 185.0 161.0 18.2 94.8 48.6 33.8 48.6 133.9 85.1 182.8 36.6 88.8 106.0 74.5 86.4 96.7 129.9 43.1 94.5 17.5 80.1 24.7 51.7 47.2 2.5 3.5 3.3 1.9 2.0 1.7 0.9 1.6 1.3 2.4 1.0 1.1 1.6 2.3 2.2 3.6 1.8 1.5 1.8 39.0 43.4 41.3 40.5 33.2 42.5 53.9 43.2 45.8 45.0 48.8 41.2 13.9 3.2 12.8 47.0 8.1 7.1 4.9 10.8 14.2 1.7 20.3 17.3 13.6 11.5 11.7 12.9 27.1 27.9 9.1 28.3 1.9 11.6 1.5 14.6 16.3 11.2 22.7 5.7 2.6 12.5 15.4 10.8 24.5 25.5 7.6 21.0 8.9 12.5 21.7 10.1 2.2 16.4 18.3 27.6 16.2 2.1 9.9 29.8 10.6 18.7 17.6 16.8 14.4 15.1 6.1 14.9 17.5 13.9 7.8 7.8 15.2 16.2 10.2 17.2 6.6 12.9 14.5 1.4 4.9 6.7 4.8 32.4 11.6 10.1 21.8 5.4 INS "IDDM1, IDDM2" ENSG00000254647 Insulin P01308 11 2159779-2161221 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism" Hormone "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 135 "pancreas: 12983.6" "Cell type enriched" "Detected in some" 21 "Pancreatic endocrine cells: 1475.2" "Cancer enriched" "Detected in single" 7165 "pancreatic cancer: 1751.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "EFO-21: 268.3;U-2 OS: 376.2;U-698: 132.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 13 "midbrain: 1.3" "CAB000048, HPA004932, CAB012098, CAB053843" Enhanced "Secreted to blood" NA NA 437000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB000048: , CAB012098: AB_300968, CAB053843: AB_620123, HPA004932: AB_1851816" "unprognostic (7.61e-2)" 19.2 4.0 0.1 0.2 0.1 49.8 0.6 0.0 0.0 0.7 0.0 12.8 1.5 1.4 0.0 1.8 0.3 3.7 5.6 0.1 0.1 40.7 1.4 1.7 5.4 0.2 0.4 2.6 12983.6 0.0 0.3 1.4 0.8 0.5 0.0 0.0 3.1 0.0 0.3 96.4 0.7 0.0 0.0 1.4 42.2 0.3 0.0 0.0 1.3 0.0 0.0 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 268.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 376.2 0.0 31.8 0.0 15.9 132.4 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 67.2 0.0 0.0 0.0 0.0 1475.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INTS12 "INT12, PHF22, SBBI22" ENSG00000138785 "Integrator complex subunit 12" Q96CB8 4 105682627-105895986 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035772, HPA041814" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies, Plasma membrane" "HPA035772: AB_10671109, HPA041814: AB_2677687" "unprognostic (5.30e-2)" "unprognostic (4.54e-2)" "unprognostic (1.84e-3)" "unprognostic (1.78e-1)" "unprognostic (3.68e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.95e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-3)" "unprognostic (3.00e-2)" "unprognostic (3.48e-2)" "unprognostic (5.93e-3)" "unprognostic (3.62e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-1)" 15.2 11.1 12.8 10.9 13.3 30.4 20.2 14.9 18.0 14.1 12.0 14.7 18.1 14.6 17.8 13.5 13.2 12.7 18.9 12.4 14.9 18.7 22.6 16.4 14.0 12.3 14.0 11.6 12.6 17.2 10.3 11.9 12.5 18.1 15.6 17.2 14.4 13.4 26.5 14.0 15.5 17.1 12.7 12.6 15.0 13.9 14.3 19.9 19.9 26.0 17.0 15.6 11.2 13.7 24.4 12.8 28.5 29.8 27.5 32.6 20.8 28.2 29.1 34.7 35.9 18.1 26.9 34.9 15.4 31.9 26.9 13.8 31.7 40.7 42.8 36.9 19.0 26.3 19.6 25.7 44.3 46.7 23.0 31.0 51.7 34.5 51.4 22.5 32.3 29.1 39.8 26.7 37.8 25.6 55.3 28.9 12.4 35.3 19.5 28.0 31.0 26.8 32.5 16.3 30.7 24.6 19.8 32.6 31.0 22.4 26.4 27.2 21.3 22.7 23.3 24.8 30.5 40.8 40.9 52.2 25.3 31.5 46.0 64.0 23.7 38.5 25.7 26.6 28.9 33.0 29.4 29.4 27.7 32.1 30.6 28.3 17.9 42.9 28.3 42.6 34.8 21.9 12.8 13.3 14.9 18.0 12.4 14.9 12.3 14.0 12.5 12.7 14.3 13.7 19.0 12.8 11.8 14.0 15.1 11.0 11.8 25.8 15.4 10.5 12.1 11.7 18.7 11.5 12.9 3.7 10.4 16.1 13.6 8.3 43.0 25.2 35.8 8.1 11.2 16.8 6.0 15.6 13.8 20.3 18.6 10.8 8.6 8.7 24.7 9.9 11.7 9.3 17.8 10.1 15.7 5.2 30.5 9.0 9.5 28.4 12.2 9.8 7.2 9.4 15.5 14.0 21.6 27.2 19.1 20.5 6.8 8.2 18.9 14.2 16.5 17.1 6.2 9.3 0.0 12.9 20.1 13.4 16.2 14.1 10.4 18.3 13.0 14.9 10.2 11.0 IPO7 "Imp7, RANBP7" ENSG00000205339 "Importin 7" O95373 11 9384652-9448127 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019002, HPA056590" Approved Approved Supported Nucleoplasm,Cytosol NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA019002: AB_1856059, HPA056590: AB_2683180" "unprognostic (1.92e-1)" "prognostic unfavorable (4.98e-4)" "unprognostic (9.50e-2)" "unprognostic (1.27e-1)" "unprognostic (3.68e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.19e-2)" "unprognostic (7.60e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (8.38e-6)" "unprognostic (3.06e-1)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (8.08e-2)" "unprognostic (2.17e-1)" "unprognostic (3.90e-3)" 37.9 29.1 24.1 31.3 25.7 22.7 40.4 27.3 30.7 35.7 27.5 34.6 27.2 33.9 29.2 37.9 31.3 31.8 50.4 23.2 28.0 41.4 38.5 28.9 30.1 27.6 27.4 33.1 33.8 38.9 13.0 41.1 27.3 32.1 34.1 47.8 33.3 33.2 110.3 25.3 26.0 43.4 26.8 22.9 25.6 12.7 27.4 31.8 54.0 93.4 34.8 51.8 22.8 29.9 148.7 110.8 130.6 104.4 129.4 165.7 104.4 176.0 112.4 127.1 136.4 99.1 132.6 138.1 62.5 136.3 115.5 113.5 187.5 136.7 210.7 66.3 154.5 114.3 118.8 100.1 80.7 177.0 83.3 106.7 144.8 84.0 195.6 129.5 152.8 46.7 174.7 80.5 167.9 60.3 107.5 86.3 129.0 136.3 130.2 111.4 205.5 63.0 105.3 137.5 51.7 101.5 78.6 153.5 129.1 103.2 70.7 87.6 120.9 155.6 107.4 162.0 190.9 23.2 95.3 93.6 102.0 93.6 86.4 0.1 1.5 0.3 1.4 2.6 2.7 1.9 1.5 2.0 3.2 1.4 1.9 1.7 0.7 3.5 3.8 1.4 1.5 1.0 24.1 25.7 27.3 30.7 23.2 28.0 27.6 27.4 27.3 26.8 27.4 29.9 41.3 67.3 71.5 19.6 46.4 144.0 103.3 44.8 68.9 40.1 65.5 42.4 131.9 25.8 59.7 35.0 58.4 52.8 39.7 27.2 33.2 34.2 4.6 55.9 92.5 55.7 31.1 50.9 43.9 42.2 63.8 58.0 47.4 99.5 37.9 56.5 25.0 46.8 35.3 35.3 49.7 38.8 32.6 48.0 92.2 7.1 28.0 56.6 39.2 17.8 39.2 31.8 13.4 28.1 44.9 45.5 32.9 35.7 47.6 150.6 26.5 45.7 48.4 39.8 13.1 96.2 71.0 21.6 19.8 82.2 147.9 36.7 37.7 49.0 50.9 127.4 IRF1 MAR ENSG00000125347 "Interferon regulatory factor 1" P10914 5 132440440-132508719 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 142.1" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 138.1;REH: 114.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011662, HPA063131" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB011662: AB_775784, HPA063131: AB_2684945" "unprognostic (1.30e-3)" "unprognostic (2.00e-2)" "unprognostic (2.47e-3)" "unprognostic (1.21e-1)" "unprognostic (2.27e-1)" "unprognostic (4.48e-2)" "unprognostic (3.67e-1)" "unprognostic (1.64e-1)" "unprognostic (1.52e-2)" "unprognostic (2.24e-2)" "unprognostic (6.93e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.09e-7)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (9.53e-3)" 53.7 19.1 8.2 88.0 7.6 142.1 29.5 8.1 9.4 21.3 7.7 46.3 84.8 21.3 11.7 24.3 24.4 32.6 25.8 7.3 7.5 32.9 54.4 119.0 86.3 17.2 8.1 18.4 15.6 7.4 17.3 22.2 15.8 36.4 38.1 2.8 28.7 16.2 16.7 19.7 68.8 33.1 8.8 117.4 47.4 13.5 10.5 66.4 25.8 13.3 45.3 63.9 24.1 8.0 26.7 22.8 2.3 8.1 22.1 18.9 42.5 14.7 58.8 41.6 52.2 11.3 79.4 26.7 15.8 18.4 64.8 35.7 7.4 33.7 14.3 54.2 7.1 33.2 8.1 6.9 138.1 14.6 34.3 36.9 9.4 31.7 32.2 26.5 22.4 19.1 6.9 97.5 13.1 15.9 87.6 32.7 3.4 9.3 14.6 114.5 23.2 31.7 22.5 27.8 6.4 3.6 14.6 30.8 13.4 10.1 4.7 24.2 13.0 20.5 8.1 12.8 19.8 74.8 27.0 19.3 24.9 27.2 15.5 175.3 167.1 257.0 157.2 244.1 106.9 68.4 104.2 129.9 95.7 62.5 63.5 91.7 621.0 136.9 272.4 52.4 122.1 160.0 8.2 7.6 8.1 9.4 7.3 7.5 17.2 8.1 15.8 8.8 10.5 8.0 369.9 102.5 114.3 1.0 216.5 88.1 129.4 66.3 306.7 14.7 216.5 186.6 17.0 47.1 58.0 22.0 33.3 24.0 396.3 183.6 19.6 112.1 92.5 242.3 170.8 223.1 87.1 36.6 1.1 114.3 42.6 224.4 212.0 288.1 105.2 32.0 58.2 14.6 49.7 1.7 1.2 137.4 57.0 73.9 228.7 9.1 27.4 134.1 72.9 7.5 257.2 16.7 399.6 2.5 1.1 88.6 140.6 7.9 248.6 270.9 155.5 22.4 110.9 46.5 13.1 516.2 225.0 1.3 6.8 118.8 82.7 11.2 301.4 20.5 94.6 95.0 IRF4 "LSIRF, MUM1" ENSG00000137265 "Interferon regulatory factor 4" Q15306 6 391752-411443 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.2;cervix: 19.0;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in some" "B-cells: 57.2;dendritic cells: 66.8;Langerhans cells: 109.7;Melanocytes: 44.4;monocytes: 56.1;Plasma cells: 235.6" "Cancer enriched" "Detected in many" 9 "melanoma: 27.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 10.4;myeloid DC: 10.6;naive B-cell: 10.8;plasmacytoid DC: 12.1;T-reg: 5.8" "Group enriched" "Detected in many" 5 "B-cells: 10.8;dendritic cells: 12.1;T-cells: 5.8" "Cell line enhanced" "Detected in some" "HDLM-2: 221.4;Karpas-707: 197.8;RPMI-8226: 200.0;U-266/70: 177.2;U-266/84: 141.3;WM-115: 109.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA002038, HPA002698, CAB013508" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB013508: , HPA002038: AB_1079148, HPA002698: AB_1851893" "prognostic favorable (6.44e-4)" "unprognostic (1.88e-3)" "unprognostic (1.00e-3)" "unprognostic (1.72e-4)" "unprognostic (2.74e-1)" "prognostic favorable (1.64e-6)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (1.89e-2)" "unprognostic (5.74e-4)" "unprognostic (8.51e-2)" "unprognostic (1.12e-1)" "unprognostic (9.18e-7)" "unprognostic (2.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.90e-1)" "unprognostic (3.65e-2)" 3.1 0.4 0.1 15.9 0.1 29.2 3.2 0.1 0.2 19.0 0.2 6.9 7.6 1.5 0.3 0.9 0.7 2.5 1.0 0.1 0.1 0.4 2.4 2.2 23.2 0.3 0.1 0.6 0.1 0.0 0.3 0.1 0.2 0.5 6.8 0.0 4.5 0.4 0.2 6.8 10.2 0.7 0.2 17.4 7.2 1.1 0.1 7.0 1.1 0.1 26.1 6.3 2.4 0.2 0.4 0.0 0.0 0.0 22.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 221.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.8 0.0 0.0 0.1 0.1 1.2 0.0 0.0 26.1 0.0 200.0 0.0 0.0 0.4 0.0 0.0 0.2 32.0 0.6 0.1 0.3 0.0 0.0 0.1 0.0 0.3 177.2 141.3 58.4 0.2 0.0 109.0 0.1 1.8 0.0 0.6 1.5 0.0 10.4 1.0 1.0 10.6 10.8 1.7 0.7 0.0 0.3 1.5 12.1 5.8 1.5 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.2 0.2 0.1 0.2 0.8 0.0 5.3 0.0 57.2 8.3 0.1 0.0 0.0 0.0 0.6 1.5 1.2 1.5 0.0 0.0 0.0 0.0 66.8 0.2 0.0 0.1 0.0 0.3 0.9 0.6 0.0 0.0 0.1 0.7 0.0 1.8 1.5 0.4 0.0 0.0 1.1 0.5 0.3 0.0 0.1 0.1 0.0 0.6 109.7 0.2 3.4 21.7 44.4 0.0 56.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 235.6 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 1.0 0.4 4.3 0.1 29.8 0.0 0.1 0.1 IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 95.4;skin 1: 114.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 387.2;Basal prostatic cells: 253.9;Basal squamous epithelial cells: 217.9;Squamous epithelial cells: 251.9;Suprabasal keratinocytes: 552.4;Urothelial cells: 290.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 61.9;HaCaT: 210.7;HBEC3-KT: 80.5;hTCEpi: 170.1;hTERT-HME1: 82.2;RT4: 78.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063121, HPA076162" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA063121: AB_2684942, HPA076162: AB_2686780" "unprognostic (2.59e-1)" "unprognostic (1.79e-3)" "unprognostic (1.74e-1)" "unprognostic (7.80e-2)" "unprognostic (1.33e-2)" "unprognostic (4.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (7.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (2.70e-1)" "unprognostic (2.66e-2)" "unprognostic (2.14e-1)" "unprognostic (4.42e-2)" 1.6 11.4 1.6 3.2 1.5 2.8 35.9 10.9 1.8 21.6 5.2 27.1 26.9 5.9 49.3 95.4 21.7 10.8 29.7 1.7 1.4 17.0 33.3 8.8 0.9 1.9 2.9 1.9 19.7 26.4 6.5 20.4 1.9 32.4 31.5 2.4 39.0 26.4 0.5 114.0 25.0 2.0 2.1 2.1 24.8 2.9 2.3 20.3 17.1 2.7 23.0 40.5 46.8 1.2 61.9 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.5 0.1 0.3 13.6 20.7 0.0 0.1 0.1 0.0 210.7 0.0 80.5 0.0 0.0 1.3 0.1 0.2 0.0 0.2 0.0 0.2 0.1 170.1 0.1 82.2 0.0 3.7 0.0 0.1 0.2 0.0 8.3 0.0 0.3 1.2 17.0 0.2 0.0 0.0 0.3 7.7 78.8 18.7 6.1 1.4 34.1 1.9 3.8 24.1 0.3 0.0 0.0 0.1 0.0 0.3 0.8 15.8 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 1.6 1.5 10.9 1.8 1.7 1.4 1.9 2.9 1.9 2.1 2.3 1.2 1.9 16.0 10.4 0.3 1.0 387.2 253.9 154.0 217.9 0.1 47.2 33.3 26.0 32.9 70.4 35.0 0.0 94.2 1.3 95.5 27.4 36.7 1.1 120.2 9.5 6.0 59.9 0.4 0.0 19.2 25.4 4.5 53.0 121.7 2.5 0.0 1.1 35.9 8.3 0.0 0.1 74.9 38.7 1.0 30.1 0.7 0.6 2.3 35.6 1.9 1.0 6.5 0.0 0.0 0.0 49.2 43.8 0.0 2.5 153.9 49.5 11.9 82.1 0.6 0.0 0.4 7.4 8.2 3.7 251.9 552.4 161.6 2.5 0.7 44.5 290.3 IRS2 ENSG00000185950 "Insulin receptor substrate 2" Q9Y4H2 13 109752695-109786583 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 51.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "hTERT-HME1: 38.1;LHCN-M2: 36.9;SH-SY5Y: 40.2;THP-1: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016944, HPA054664" Approved Supported Aggresome,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Cytosol Aggresome "CAB016944: , HPA054664: AB_2682563" "unprognostic (2.87e-3)" "unprognostic (5.73e-3)" "unprognostic (4.39e-2)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (5.49e-3)" "unprognostic (2.10e-1)" "unprognostic (9.28e-2)" "unprognostic (9.70e-2)" "unprognostic (2.34e-3)" "unprognostic (1.17e-1)" "unprognostic (2.09e-2)" "unprognostic (6.21e-3)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (3.17e-2)" "unprognostic (1.24e-1)" 26.2 16.5 22.2 5.9 21.8 51.3 18.9 12.1 28.4 10.7 3.9 11.3 4.4 13.0 6.3 4.2 7.7 4.0 13.0 32.2 22.9 3.5 22.1 11.1 2.3 29.4 24.5 18.6 4.3 3.6 19.1 6.7 24.8 13.3 3.4 6.0 11.6 6.1 21.4 15.5 6.0 4.7 13.6 5.4 7.8 3.0 25.2 2.3 5.5 7.7 2.2 7.1 8.6 20.1 5.8 6.6 4.2 0.0 34.5 6.9 2.3 6.3 7.4 3.8 3.1 0.6 7.0 0.0 3.9 4.5 5.4 2.6 2.2 5.6 4.7 2.3 29.5 2.8 9.3 0.0 34.8 10.7 3.3 14.5 29.6 1.1 38.1 24.5 1.4 0.5 1.9 0.0 36.9 3.0 0.1 31.1 4.5 3.2 1.4 13.1 3.8 2.8 10.6 1.5 6.1 40.2 3.3 0.1 27.2 3.5 0.8 62.8 0.1 7.8 0.0 0.5 8.5 0.0 3.1 2.1 5.8 10.2 13.7 1.5 0.6 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.3 0.0 0.2 0.0 0.2 0.1 22.2 21.8 12.1 28.4 32.2 22.9 29.4 24.5 24.8 13.6 25.2 20.1 13.7 32.1 33.8 53.8 31.1 113.9 48.0 100.2 81.4 25.8 68.9 98.4 72.3 60.1 79.5 31.3 114.7 20.3 40.0 71.2 5.9 36.4 47.6 81.6 110.6 13.4 122.6 34.5 51.3 3.1 11.1 52.0 28.1 188.5 25.3 25.8 20.0 142.9 24.1 25.2 42.2 42.0 52.9 143.5 24.4 12.3 37.3 131.2 129.9 29.0 59.3 32.4 17.5 46.3 34.8 30.8 44.4 20.3 7.9 76.8 77.3 3.9 40.3 30.6 26.3 57.1 44.0 21.2 10.2 74.6 126.2 30.6 37.5 63.1 42.7 53.6 IRS4 "IRS-4, PY160" ENSG00000133124 "Insulin receptor substrate 4" O14654 X 108719946-108736563 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.7;choroid plexus: 8.0;pituitary gland: 5.3" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 2.9;Oligodendrocytes: 1.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8" "Region enhanced" "Detected in many" "hypothalamus: 14.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 9.4;NTERA-2: 1.3;RT4: 3.1;WM-115: 2.2" "Group enriched" "Detected in many" 5 "basal ganglia: 11.7;hypothalamus: 45.0" "Group enriched" "Detected in many" 5 "basal ganglia: 14.5;hypothalamus: 36.7" HPA017372 Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017372: AB_2669600" "unprognostic (3.74e-3)" "unprognostic (3.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" "unprognostic (1.77e-1)" "unprognostic (9.28e-4)" "unprognostic (8.71e-2)" 0.0 0.0 4.1 0.0 1.3 0.0 0.0 0.0 0.5 1.0 8.0 0.0 0.0 1.4 0.5 0.0 0.2 0.0 0.0 1.3 14.7 0.0 0.0 0.0 0.0 2.0 2.6 4.6 0.0 0.0 5.3 0.0 3.3 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.5 0.9 0.0 0.2 0.0 10.6 3.8 1.8 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 1.3 0.0 0.5 1.3 14.7 2.0 2.6 3.3 0.9 10.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 ITGA2 CD49B ENSG00000164171 "Integrin subunit alpha 2" P17301 5 52989340-53094779 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 406.2;Oligodendrocytes: 370.9;Pancreatic endocrine cells: 558.7;Prostatic glandular cells: 299.3;Urothelial cells: 363.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 91.4;HaCaT: 92.5;hTERT-RPE1: 83.2;HUVEC TERT2: 83.5;TIME: 71.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017690, HPA060991, HPA063556" Enhanced Approved Nucleoplasm,Cytosol Yes No 43000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB017690: AB_1124939, HPA060991: AB_2684405, HPA063556: AB_2685040" "unprognostic (8.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "unprognostic (3.70e-2)" "unprognostic (2.67e-3)" "unprognostic (2.38e-2)" "unprognostic (1.87e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (4.27e-1)" "unprognostic (3.88e-2)" "unprognostic (2.87e-2)" "unprognostic (1.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" 1.4 12.8 2.4 4.9 6.7 0.4 7.8 4.4 3.7 5.0 0.9 6.1 7.7 4.9 7.4 11.0 2.6 9.0 1.1 2.4 4.2 9.8 0.5 12.5 0.9 4.8 4.9 1.0 1.6 9.3 1.2 4.8 5.4 6.6 5.9 2.4 10.4 11.1 0.5 17.1 7.7 2.4 3.3 6.8 7.5 0.4 4.8 4.3 2.3 0.7 4.6 15.6 8.0 12.9 60.4 15.4 1.3 0.8 3.9 7.1 4.5 60.2 91.4 2.2 3.6 29.0 41.8 0.1 9.8 25.4 33.5 92.5 4.9 67.1 8.5 0.0 4.4 4.3 3.7 17.5 13.3 0.7 1.3 2.9 11.4 59.2 10.5 83.2 83.5 3.1 0.1 0.2 1.6 11.4 0.6 0.1 3.7 15.7 29.6 0.0 0.4 0.1 18.9 32.0 0.6 3.2 3.2 4.1 6.1 2.3 9.6 0.2 71.2 10.8 6.3 1.7 12.1 0.0 0.1 0.1 64.0 0.0 48.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 6.7 4.4 3.7 2.4 4.2 4.8 4.9 5.4 3.3 4.8 12.9 7.4 57.7 13.7 9.1 0.6 151.0 406.2 141.3 56.9 2.7 24.4 39.0 1.3 15.7 133.2 53.3 4.2 1.9 0.9 23.2 9.8 144.0 0.1 20.3 5.0 39.0 13.8 0.0 0.5 169.3 2.2 11.6 13.3 90.6 1.3 45.4 5.3 0.2 0.3 0.0 0.9 37.8 20.3 0.0 6.1 0.2 1.2 2.5 12.4 14.0 1.1 14.7 0.0 0.0 370.9 558.7 20.3 0.0 2.6 299.3 20.6 3.8 103.6 4.3 0.0 4.4 12.1 0.0 1.3 57.0 37.2 0.4 5.8 23.7 30.9 363.9 ITGA2B "CD41, CD41B, GP2B, PPP1R93" ENSG00000005961 "Integrin subunit alpha 2b" P08514 17 44372180-44389649 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.6;epididymis: 10.7;lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Early spermatids: 16.1;Erythroid cells: 43.5;granulocytes: 17.8;Late spermatids: 24.8;Macrophages: 23.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "basophil: 64.5" "Lineage enriched" "Detected in single" 75 "granulocytes: 64.5" "Group enriched" "Detected in some" 14 "HEL: 404.6;HMC-1: 631.7" "Not detected" "Not detected" "CAB018611, HPA031168, HPA031169, HPA031170, HPA031171" Enhanced Approved "Plasma membrane" NA NA 90000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB018611: AB_2265153, HPA031168: AB_10664706, HPA031169: AB_10669671, HPA031170: AB_10696214, HPA031171: AB_10669773" "unprognostic (6.11e-2)" "unprognostic (3.23e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "unprognostic (3.98e-3)" "unprognostic (4.23e-5)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (7.22e-2)" "unprognostic (2.97e-3)" "unprognostic (1.30e-1)" "unprognostic (8.83e-9)" "unprognostic (7.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.25e-1)" 0.8 0.2 3.7 0.2 3.6 16.6 0.4 4.0 4.8 1.5 3.8 0.3 0.0 0.9 10.7 0.3 1.5 0.8 1.4 3.5 3.6 1.0 0.5 5.1 0.2 3.6 3.5 1.5 0.1 1.3 1.9 1.1 3.6 0.6 0.1 1.6 0.1 0.8 0.6 0.1 0.3 0.2 3.3 11.2 0.3 2.9 3.5 0.1 3.1 1.1 0.1 0.2 0.7 3.7 0.5 0.7 2.2 0.3 0.1 0.3 18.4 0.3 0.1 0.8 0.6 0.0 0.2 0.0 0.3 0.0 0.2 0.6 1.8 0.0 0.4 0.4 1.1 404.6 0.3 1.3 0.0 0.2 631.7 0.4 0.0 0.2 0.0 0.0 0.0 0.3 0.7 1.1 0.0 0.7 0.5 36.4 0.8 0.0 0.7 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.5 0.5 0.1 1.5 4.5 0.9 0.3 0.2 0.7 0.0 0.0 0.4 0.2 0.3 0.4 0.3 0.8 64.5 0.3 4.0 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.5 0.0 0.0 0.8 0.0 19.3 3.7 3.6 4.0 4.8 3.5 3.6 3.6 3.5 3.6 3.3 3.5 3.7 0.3 0.0 1.5 1.0 0.4 0.3 0.4 0.1 1.8 5.1 0.2 1.1 1.5 1.5 1.3 5.5 8.4 1.3 0.1 0.6 0.0 0.0 16.1 1.0 0.7 2.1 0.0 43.5 4.1 0.0 1.4 1.1 0.0 3.2 17.8 0.1 3.6 0.0 0.2 3.3 2.8 0.0 0.0 3.1 0.7 24.8 1.8 23.0 0.0 1.0 2.9 1.3 0.0 9.5 4.6 0.1 0.0 1.9 0.1 0.3 0.0 0.0 0.0 3.0 0.0 1.8 0.7 3.4 7.4 0.5 0.0 0.7 0.6 0.1 0.3 0.3 ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 111.9;Exocrine glandular cells: 105.1;Pancreatic endocrine cells: 245.6;Urothelial cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 647.2;hTERT-RPE1: 572.8;RPTEC TERT1: 562.0;U-87 MG: 920.8;WM-115: 570.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" 17.5 29.8 5.3 9.9 5.4 0.4 17.3 6.0 6.1 14.8 5.2 25.4 30.4 21.3 11.7 24.1 24.5 17.9 13.2 5.0 10.9 68.9 2.2 65.8 3.0 7.5 6.6 12.8 15.9 17.7 21.1 26.7 11.9 19.5 15.5 4.4 19.4 15.7 9.0 30.8 26.7 15.6 4.2 11.1 24.5 2.1 7.8 5.9 43.5 4.1 6.2 46.7 17.1 4.0 181.8 234.9 1.4 7.5 4.3 17.5 37.3 83.4 177.9 123.1 93.2 5.3 276.2 0.4 507.9 59.5 400.4 126.8 2.2 647.2 73.9 22.9 3.5 0.1 56.8 1.6 105.1 0.3 5.0 21.6 313.5 123.2 540.7 572.8 91.6 9.1 0.1 2.6 236.0 52.9 0.7 0.5 5.5 81.2 141.0 0.4 12.1 13.7 562.0 311.1 9.7 3.9 89.8 12.2 205.0 56.2 21.1 2.4 200.8 541.8 169.4 5.6 329.5 8.1 14.2 5.9 920.8 1.9 570.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 5.4 6.0 6.1 5.0 10.9 7.5 6.6 11.9 4.2 7.8 4.0 8.5 54.5 30.1 3.6 3.4 57.4 63.5 63.5 48.3 18.0 17.1 32.0 5.3 27.1 26.2 77.3 25.0 2.8 1.3 91.2 0.0 111.9 0.5 26.4 3.1 14.7 14.5 0.0 24.3 105.1 3.2 5.3 47.4 20.7 3.8 3.4 8.9 0.3 1.1 3.3 20.0 25.1 16.2 1.2 8.2 0.6 1.8 2.0 17.8 8.4 4.3 3.1 2.1 3.0 0.8 245.6 26.7 4.1 4.5 72.6 69.6 4.4 21.7 16.2 13.1 5.6 23.4 0.5 1.6 17.0 23.2 1.8 3.8 0.9 44.7 104.2 ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 47.1;lymphoid tissue: 74.1" "Group enriched" "Detected in many" 4 "B-cells: 86.3;dendritic cells: 151.5;Erythroid cells: 169.3;Macrophages: 72.0;monocytes: 73.8;NK-cells: 126.7;Plasma cells: 141.6;T-cells: 129.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 164.0;HEL: 308.1;JURKAT: 142.3;MOLT-4: 373.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 12.9" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" 3.3 2.3 1.2 31.5 0.5 47.1 3.8 4.1 1.5 12.7 3.0 8.7 8.7 3.3 1.4 2.3 1.5 9.8 1.5 4.1 1.3 2.7 5.7 12.7 37.2 1.4 1.6 1.4 1.5 0.9 0.4 14.7 2.9 3.5 10.3 8.6 2.9 2.5 0.6 1.2 11.7 5.2 0.9 45.5 10.4 0.8 2.4 74.1 2.0 0.9 26.1 9.5 1.4 1.3 0.3 1.3 4.6 0.1 38.9 55.0 0.0 42.3 46.7 19.5 42.0 0.0 0.0 32.4 0.2 164.0 17.4 23.4 14.0 0.7 22.3 0.0 3.4 308.1 1.1 0.0 4.0 123.4 6.8 39.2 0.0 1.2 0.0 20.5 2.3 142.3 0.1 45.5 12.7 0.0 373.6 117.9 3.7 0.0 0.2 78.1 20.3 5.1 0.0 0.0 8.2 2.6 0.1 0.4 1.4 1.6 0.0 82.9 23.2 6.5 4.1 0.7 8.5 90.9 77.5 18.6 3.7 59.5 90.3 29.5 55.0 137.4 42.0 131.3 32.1 37.3 46.9 52.4 66.0 33.0 26.5 33.1 7.1 32.2 139.6 17.5 13.4 65.2 1.2 0.5 4.1 1.5 4.1 1.3 1.4 1.6 2.9 0.9 2.4 1.3 2.8 0.0 6.7 0.0 86.3 0.3 0.2 1.2 0.0 2.3 1.1 1.4 1.2 2.8 1.8 0.0 6.2 0.1 151.5 0.1 0.0 0.0 0.0 4.4 6.5 1.4 0.0 169.3 9.4 0.0 0.3 6.3 7.1 6.4 18.9 0.3 1.8 0.2 5.9 0.0 0.5 0.1 0.0 24.5 4.4 0.0 0.6 72.0 0.0 7.5 73.8 0.2 126.7 15.6 0.3 0.0 0.4 0.0 141.6 0.3 0.0 0.2 0.8 6.4 0.0 0.7 8.3 0.7 1.2 0.3 0.6 0.4 129.9 0.4 0.2 0.2 ITGA5 "CD49e, FNRA" ENSG00000161638 "Integrin subunit alpha 5" P08648 12 54395261-54419266 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 398.8;smooth muscle: 361.9;urinary bladder: 386.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 101.5;Extravillous trophoblasts: 391.9;Hepatic stellate cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 615.4;HUVEC TERT2: 1360.8;TIME: 1277.7;U-87 MG: 623.6" "Region enriched" "Detected in many" 5 "basal ganglia: 10.4" "Low region specificity" "Detected in many" "HPA002642, CAB009008" Enhanced NA NA 26000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB009008: AB_647474, HPA002642: AB_1078469" "unprognostic (7.51e-3)" "prognostic unfavorable (4.07e-6)" "prognostic unfavorable (8.43e-4)" "unprognostic (1.58e-1)" "unprognostic (8.51e-3)" "prognostic unfavorable (2.91e-4)" "prognostic unfavorable (2.23e-5)" "prognostic unfavorable (2.44e-4)" "unprognostic (2.76e-2)" "unprognostic (6.19e-2)" "unprognostic (8.99e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (1.32e-8)" "unprognostic (2.11e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.89e-4)" "unprognostic (2.18e-3)" 114.4 47.1 8.7 136.2 9.2 46.4 69.1 9.2 13.8 64.0 9.7 398.8 15.3 106.1 5.0 72.3 71.1 50.8 113.9 8.5 9.0 26.6 48.6 121.7 17.5 11.3 9.9 39.3 20.9 14.9 10.5 91.6 11.3 141.9 40.6 1.3 24.5 114.9 29.1 50.5 87.6 361.9 10.6 16.3 90.8 4.0 17.1 13.2 40.5 25.7 12.5 386.5 76.9 9.8 65.4 23.9 43.6 0.6 130.8 278.7 113.5 286.0 308.2 300.9 220.6 17.1 15.3 0.5 206.9 308.5 149.1 10.1 12.5 81.4 197.4 0.4 12.2 28.1 31.3 1.1 179.5 88.7 44.4 206.8 39.2 351.9 258.3 615.4 1360.8 15.6 25.6 0.8 165.4 6.4 13.7 99.2 18.1 4.2 19.1 13.7 29.2 6.2 46.9 1.1 0.1 0.6 57.7 4.3 2.2 93.8 7.1 79.9 1277.7 353.0 62.3 85.9 121.5 0.3 3.6 0.7 623.6 83.0 118.5 16.4 64.9 0.5 14.2 27.3 11.2 0.1 10.9 10.9 62.6 0.3 7.7 6.6 89.1 26.4 24.0 3.4 4.9 42.9 8.7 9.2 9.2 13.8 8.5 9.0 11.3 9.9 11.3 10.6 17.1 9.8 58.3 3.2 4.4 1.6 2.7 14.3 3.4 11.3 4.0 1.1 6.1 2.8 16.3 14.3 4.9 0.0 0.0 5.4 19.6 0.0 0.0 34.0 0.3 1.7 32.1 101.5 0.0 3.4 1.4 3.4 391.9 45.0 0.5 3.0 19.7 5.1 88.9 27.1 28.4 0.0 1.2 0.0 2.0 22.8 58.5 0.5 6.5 38.5 10.6 14.0 24.6 0.0 21.6 0.0 0.2 8.8 0.0 4.5 8.7 3.6 0.0 0.2 1.8 1.1 13.1 11.1 30.7 0.2 0.7 1.3 10.7 34.6 14.3 2.4 0.0 2.0 ITGA6 CD49f ENSG00000091409 "Integrin subunit alpha 6" P23229 2 172427354-172506459 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 327.2;Basal keratinocytes: 244.7;Urothelial cells: 247.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 144.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.9" "Group enriched" "Detected in many" 28 "granulocytes: 22.9;NK-cells: 7.1;T-cells: 12.8" "Cell line enhanced" "Detected in many" "BJ: 326.2;HaCaT: 356.8;HBEC3-KT: 705.8;hTCEpi: 298.9;hTERT-HME1: 301.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009009, HPA012696, HPA027582" Enhanced NA NA 3300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB009009: AB_2128038, HPA012696: AB_1851822, HPA027582: AB_10602606" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (2.59e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.19e-1)" "unprognostic (1.61e-3)" "unprognostic (9.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "prognostic favorable (2.35e-11)" "unprognostic (3.35e-2)" "unprognostic (3.32e-1)" "unprognostic (2.98e-2)" "unprognostic (1.21e-3)" 45.9 8.3 20.1 27.8 16.7 5.8 55.6 16.6 20.3 64.3 42.8 65.4 74.2 43.1 9.5 25.1 25.3 37.2 29.2 17.2 20.9 42.7 8.8 29.3 18.7 20.8 18.8 5.6 42.0 14.0 6.2 76.8 19.3 24.4 62.4 7.3 81.0 30.8 27.7 46.6 67.4 39.0 20.5 41.2 66.1 26.1 25.0 33.9 21.1 42.6 21.4 55.0 26.8 16.5 77.5 64.8 26.7 49.1 1.4 0.9 146.3 326.2 34.6 32.1 20.0 36.2 141.3 0.7 90.9 86.8 73.8 356.8 17.7 705.8 58.1 0.7 16.6 1.9 64.8 58.7 4.8 21.4 2.4 6.2 298.9 2.0 301.4 32.9 209.6 40.8 0.3 5.5 41.6 3.7 5.9 17.8 48.2 214.2 54.5 1.1 82.3 1.6 48.0 106.6 0.8 3.4 61.2 0.1 69.7 28.0 13.1 1.4 97.9 44.9 41.1 84.2 56.8 4.8 3.6 1.9 1.7 7.2 185.0 4.4 0.2 22.9 5.3 0.0 10.7 0.2 6.7 6.4 0.1 0.5 12.8 5.9 0.7 7.1 0.0 0.0 8.1 4.3 20.1 16.7 16.6 20.3 17.2 20.9 20.8 18.8 19.3 20.5 25.0 16.5 327.2 9.6 19.5 88.5 8.8 244.7 236.4 43.4 88.8 1.4 55.0 72.8 32.5 22.8 10.5 27.6 56.3 103.8 14.4 139.6 5.9 34.4 31.2 82.5 34.8 196.0 57.4 1.7 4.0 62.1 26.5 20.8 219.7 149.3 8.2 103.4 11.7 21.5 25.5 1.7 6.1 128.8 20.3 3.2 20.8 46.8 4.1 10.0 51.6 119.9 1.7 1.3 29.9 1.5 8.8 127.9 104.2 2.6 109.0 184.8 54.5 52.2 9.2 13.9 0.0 11.8 18.4 7.7 20.2 141.5 84.0 22.3 30.1 44.0 146.3 247.6 ITGAM "CD11B, CR3A, MAC-1" ENSG00000169896 "Integrin subunit alpha M" P11215 16 31259967-31332892 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Innate immunity" "Integrin, Receptor" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 182.8" "Group enriched" "Detected in many" 4 "dendritic cells: 45.4;granulocytes: 35.5;Hofbauer cells: 47.2;Kupffer cells: 117.7;Langerhans cells: 45.5;Macrophages: 83.2;Microglial cells: 41.2;monocytes: 87.4;NK-cells: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HMC-1: 50.0;NB-4: 19.9;U-937: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002274, CAB025091, CAB072870" Enhanced NA NA 1000000 "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB025091: , CAB072870: AB_2665722, HPA002274: AB_1078435" "unprognostic (1.82e-2)" "unprognostic (1.70e-2)" "unprognostic (8.78e-2)" "unprognostic (2.54e-2)" "unprognostic (2.40e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (3.29e-3)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.93e-5)" "unprognostic (9.89e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (3.99e-2)" "unprognostic (5.03e-2)" 13.4 4.7 3.4 24.7 3.5 182.8 3.0 4.5 4.2 3.3 4.8 3.0 2.2 2.0 0.7 2.6 2.3 5.9 2.9 3.6 5.1 1.0 3.5 16.4 7.4 6.7 5.7 1.6 2.3 1.3 0.1 7.7 7.3 1.5 3.4 0.3 2.4 2.2 1.4 1.7 3.5 11.2 6.5 13.1 3.1 1.4 8.6 5.2 1.0 3.1 10.4 8.0 0.2 10.8 0.8 1.8 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.5 0.8 1.3 0.9 0.0 0.4 0.1 0.0 0.4 0.0 7.6 0.0 1.0 0.0 0.0 0.0 1.8 50.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.3 0.1 1.0 0.0 2.2 0.0 0.0 0.0 0.5 0.4 0.0 0.2 4.3 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 22.6 0.1 93.3 55.7 70.2 31.1 20.9 1.9 4.8 3.3 9.5 9.5 1.0 0.9 7.7 58.4 54.4 3.2 0.6 1.2 27.0 3.4 3.5 4.5 4.2 3.6 5.1 6.7 5.7 7.3 6.5 8.6 10.8 1.4 3.2 9.8 0.7 9.3 1.1 0.3 1.5 0.0 0.0 1.8 3.8 2.3 4.3 1.8 0.0 0.0 0.3 45.4 0.0 0.0 1.2 0.5 0.3 0.4 1.6 3.6 9.4 1.0 0.0 0.7 1.1 1.1 0.5 35.5 0.5 2.2 1.2 47.2 0.0 1.0 0.1 0.0 117.7 45.5 1.8 0.3 83.2 0.0 41.2 87.4 0.0 75.2 3.0 0.3 0.9 0.0 0.0 4.5 0.5 0.0 0.2 0.9 0.0 13.1 1.2 0.5 0.7 0.9 0.5 1.0 0.8 14.9 0.0 0.3 0.2 ITGAV "CD51, MSK8, VNRA, VTNR" ENSG00000138448 "Integrin subunit alpha V" P06756 2 186590056-186680901 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "RT4: 369.7;SuSa: 297.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002499, HPA004856" Supported Approved "Focal adhesion sites,Cytosol" NA NA 2000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites, Cytosol" "CAB002499: AB_563594, HPA004856: AB_1846316" "unprognostic (4.03e-2)" "unprognostic (5.17e-3)" "unprognostic (1.22e-2)" "unprognostic (5.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.48e-2)" "unprognostic (6.95e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (5.84e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.61e-1)" "unprognostic (9.11e-2)" "unprognostic (8.07e-2)" 39.9 38.7 20.1 36.5 30.8 6.4 27.7 39.7 23.5 39.7 40.3 20.1 15.9 36.8 10.5 24.5 26.3 47.3 80.0 18.2 32.7 52.1 18.0 25.7 15.8 42.5 33.0 64.7 25.7 82.7 11.9 47.4 46.4 29.8 21.6 80.4 32.1 28.1 16.3 41.4 16.3 56.7 45.3 21.4 34.2 14.7 30.2 18.0 62.6 30.5 21.6 43.1 16.0 54.6 49.1 57.5 37.4 119.9 134.1 90.0 141.7 93.8 75.5 32.5 32.5 50.7 164.0 0.4 179.7 106.3 113.4 60.2 19.3 88.5 46.7 9.7 17.2 11.7 69.1 69.6 52.8 8.3 7.0 65.8 41.3 72.7 61.1 194.1 78.7 5.9 11.6 23.9 87.4 19.4 5.0 6.8 28.3 29.1 28.5 0.1 76.2 6.8 83.5 369.7 7.7 23.0 108.6 33.2 40.1 297.0 26.2 22.4 240.5 199.4 61.9 41.4 80.3 5.9 10.4 5.5 80.3 3.3 100.6 6.2 0.6 0.9 0.4 1.1 0.3 0.1 0.2 0.4 0.4 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.6 0.2 20.1 30.8 39.7 23.5 18.2 32.7 42.5 33.0 46.4 45.3 30.2 54.6 39.8 28.9 22.9 134.8 4.9 128.4 64.0 127.7 42.7 118.4 50.4 23.4 145.5 80.1 35.3 77.3 77.2 55.1 9.4 32.4 1.9 78.7 0.6 61.7 61.1 47.2 7.3 2.1 36.3 101.8 26.9 65.4 57.6 100.2 49.5 21.2 27.8 18.2 27.6 15.2 35.9 19.9 14.2 44.3 56.7 3.1 19.3 29.3 46.2 75.9 17.4 70.9 2.1 184.5 156.1 165.9 23.8 25.9 9.2 103.4 11.2 32.4 27.0 60.2 32.9 29.0 63.3 1.7 2.4 27.7 103.7 39.7 10.9 18.1 15.5 77.7 ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1206.9;Pancreatic endocrine cells: 1393.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 2711.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" 491.9 179.3 61.5 241.5 78.2 81.5 216.2 75.0 90.9 259.2 68.3 265.3 147.4 330.4 171.7 168.6 172.0 347.4 390.3 60.2 74.3 180.4 287.1 233.6 118.0 88.4 80.6 157.1 135.3 145.4 59.8 459.5 88.9 248.1 223.6 27.7 130.7 427.7 157.9 92.2 150.8 710.0 76.6 204.7 160.1 91.2 86.4 77.5 161.5 194.5 106.2 357.4 119.1 88.9 638.0 907.0 495.4 559.6 1183.4 1019.5 398.1 2063.9 1239.6 999.0 903.9 215.9 1478.2 164.5 354.1 1830.9 638.0 438.9 149.1 1204.1 1122.0 163.1 112.7 195.8 416.3 253.6 826.4 48.3 195.5 1027.7 658.2 1040.8 426.0 2711.1 1263.6 81.0 136.6 76.5 1700.8 109.0 80.1 46.7 107.4 200.6 428.2 52.0 357.0 30.9 1454.8 186.2 108.0 271.4 649.9 114.6 498.2 813.7 153.9 175.0 1362.6 1280.0 712.2 904.2 719.7 64.7 14.8 91.2 956.6 198.2 518.5 7.5 35.1 16.1 83.4 69.8 22.8 109.6 191.8 138.7 33.9 40.3 24.9 68.4 9.0 90.3 108.2 11.4 266.8 117.2 61.5 78.2 75.0 90.9 60.2 74.3 88.4 80.6 88.9 76.6 86.4 88.9 631.5 342.9 143.8 26.4 118.0 546.7 435.5 531.6 208.3 32.8 147.1 307.5 210.8 241.6 268.1 226.2 31.3 210.3 217.8 179.8 13.7 1206.9 6.6 194.6 437.9 421.1 193.3 153.0 37.2 411.3 515.2 374.7 95.8 406.5 88.7 561.8 375.9 268.1 179.8 38.7 52.4 97.4 213.6 170.1 206.7 18.3 254.5 217.8 343.3 67.5 119.4 72.0 111.2 42.7 66.8 1393.7 128.5 601.8 181.2 412.5 75.6 68.7 171.5 45.5 637.7 236.3 724.0 10.1 76.0 84.4 170.5 219.7 211.3 225.6 127.0 296.1 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 51.4" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Late spermatids: 8.8;Macrophages: 15.8;Proximal tubular cells: 4.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 5.4;neutrophil: 2.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "EFO-21: 167.8;HEL: 163.4;RPTEC TERT1: 109.8;U-87 MG: 78.3;WM-115: 255.9" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 38000000 "Cluster 34: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 8.0 0.6 0.3 9.5 0.7 6.2 5.3 0.7 1.0 3.8 1.0 16.9 3.5 13.2 2.6 4.2 7.6 3.5 5.5 0.5 0.8 15.0 3.4 5.6 0.9 2.3 1.0 1.5 0.7 1.2 1.2 4.5 2.0 4.8 7.0 0.9 2.6 16.1 1.5 2.7 5.8 22.9 1.2 2.9 3.8 2.5 1.2 0.3 51.4 2.4 1.2 9.6 2.6 1.1 0.1 1.5 0.7 0.1 8.6 3.8 0.1 4.7 23.1 9.6 8.6 0.3 0.1 0.6 167.8 1.2 13.4 0.0 0.1 0.0 12.6 3.4 0.0 163.4 0.5 0.0 7.8 0.0 0.2 3.4 0.0 54.6 1.4 6.7 43.6 2.5 0.5 0.3 2.1 0.0 1.0 0.1 0.1 0.0 0.8 0.0 4.2 0.0 109.8 0.2 0.0 0.5 5.6 0.0 33.2 8.8 0.1 0.2 47.1 2.1 2.4 1.3 11.7 0.2 0.1 1.1 78.3 0.0 255.9 5.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.1 0.1 0.1 0.0 6.8 0.3 0.7 0.7 1.0 0.5 0.8 2.3 1.0 2.0 1.2 1.2 1.1 1.3 0.0 0.0 0.0 0.5 0.1 0.2 0.9 0.0 0.0 0.1 0.3 0.8 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 3.9 0.8 0.9 3.1 0.0 0.0 0.4 0.4 0.0 2.1 0.0 0.9 0.0 0.6 1.8 0.7 0.8 0.0 0.6 0.0 0.0 0.3 0.7 8.8 0.3 15.8 0.0 1.0 0.4 0.0 0.0 0.0 0.4 1.5 0.0 1.2 0.0 0.3 0.0 4.6 0.2 0.0 6.6 0.3 2.1 0.0 2.0 0.1 0.4 1.2 0.3 0.4 0.0 0.2 ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 200.6;skin 1: 205.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 173.6;Distal enterocytes: 133.3;Gastric mucus-secreting cells: 165.1;Pancreatic endocrine cells: 284.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 897.3;HaCaT: 345.1;HBEC3-KT: 768.6;hTCEpi: 256.9;RT4: 254.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 37.4" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" 39.2 5.3 82.8 12.4 87.8 1.6 66.6 74.9 91.8 58.4 76.4 87.5 56.9 24.0 3.6 101.2 43.8 20.0 22.7 80.5 86.9 18.2 5.6 18.4 4.5 104.6 104.8 8.5 24.5 2.8 21.1 35.4 82.6 85.3 15.7 8.7 200.6 18.5 6.8 205.9 75.5 6.4 102.4 76.9 79.9 4.9 82.0 4.1 17.6 6.0 7.2 58.4 98.8 99.6 172.7 148.5 0.3 2.1 0.4 1.3 199.2 0.7 0.6 0.5 0.9 16.1 897.3 0.1 31.5 0.3 1.3 345.1 1.0 768.6 0.5 0.7 0.6 0.9 39.6 17.0 1.2 0.2 1.8 1.1 256.9 0.6 159.2 18.0 5.5 0.6 0.5 15.7 0.1 95.8 2.0 2.0 1.0 92.8 127.8 2.7 4.4 2.2 204.8 254.9 0.2 1.9 4.9 15.2 2.2 5.3 63.9 1.5 16.9 4.6 7.8 0.7 1.9 5.6 2.1 0.7 2.0 0.8 2.7 0.0 0.2 0.0 0.4 0.4 1.1 0.7 0.1 0.5 0.0 2.0 0.4 0.3 0.7 0.0 0.0 4.6 0.8 0.4 82.8 87.8 74.9 91.8 80.5 86.9 104.6 104.8 82.6 102.4 82.0 99.6 26.9 12.8 2.2 50.3 1.4 49.5 45.1 173.6 67.2 0.3 21.2 36.6 7.5 25.8 38.9 23.9 2.1 89.8 1.8 133.3 1.9 33.3 0.4 61.3 5.7 26.8 9.6 0.8 0.7 28.8 20.2 5.2 165.1 60.2 2.5 1.1 17.9 0.4 9.4 0.0 0.7 59.2 18.3 0.3 5.4 0.4 3.7 1.9 12.4 1.9 0.1 34.4 0.0 1.5 0.7 284.4 68.4 1.5 2.6 17.1 94.0 2.6 53.3 1.0 0.0 1.2 5.0 1.1 8.2 28.1 13.1 111.1 1.8 0.5 60.1 42.0 ITGB5 ENSG00000082781 "Integrin subunit beta 5" P18084 3 124761948-124901418 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 459.9;hTERT-RPE1: 508.7;WM-115: 477.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001820, CAB022050" Approved Approved "Plasma membrane,Mitochondria" NA NA 64000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Mitochondria" "CAB022050: , HPA001820: AB_1079142" "unprognostic (2.63e-1)" "unprognostic (1.04e-1)" "unprognostic (3.57e-1)" "unprognostic (4.44e-2)" "unprognostic (1.37e-2)" "unprognostic (6.07e-2)" "unprognostic (3.49e-3)" "unprognostic (3.16e-3)" "unprognostic (1.68e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.16e-1)" "unprognostic (2.16e-3)" "unprognostic (2.49e-3)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (4.38e-3)" 102.7 32.5 24.4 26.0 33.4 3.3 71.3 32.6 20.3 84.7 71.0 48.1 33.1 75.9 16.4 54.9 33.2 71.7 68.8 24.6 28.7 48.6 51.4 53.9 6.0 38.2 32.9 28.0 23.1 21.8 20.5 82.3 35.4 37.3 24.9 14.3 49.6 46.9 30.0 88.9 32.5 60.1 32.3 41.0 29.7 13.5 32.5 12.2 34.3 33.7 9.9 40.3 70.0 35.8 189.1 459.9 32.4 82.7 296.6 84.2 166.3 197.5 120.0 35.9 57.6 92.6 240.3 0.8 93.5 336.3 177.0 148.0 29.5 102.7 31.2 2.0 20.1 66.3 69.5 98.0 51.0 0.4 116.8 51.2 23.2 91.1 46.9 508.7 121.2 0.2 60.7 98.1 122.7 190.0 0.8 1.1 145.8 105.1 50.4 0.4 52.2 71.8 98.8 41.2 0.9 67.5 146.6 214.5 165.7 56.4 121.9 4.2 318.2 134.9 200.7 118.5 103.7 16.6 18.4 1.3 141.3 0.8 477.0 0.3 0.2 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.0 2.5 24.4 33.4 32.6 20.3 24.6 28.7 38.2 32.9 35.4 32.3 32.5 35.8 50.4 6.4 6.7 55.5 1.0 17.2 23.1 18.8 6.2 8.1 20.6 27.2 28.9 42.9 10.0 29.5 4.2 68.5 0.6 34.9 11.7 38.3 10.7 22.0 21.4 27.5 3.5 2.7 0.9 18.8 7.4 52.1 11.2 13.4 0.0 135.9 31.1 39.1 72.3 35.3 18.1 12.9 2.0 36.8 17.5 4.1 20.2 28.5 10.6 60.9 0.4 50.2 0.0 16.6 12.5 70.4 27.0 16.6 0.6 24.9 21.0 10.7 6.2 14.9 39.5 31.3 52.1 2.6 7.0 15.6 22.3 55.1 1.7 1.0 16.3 14.8 ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.8;Alveolar cells type 2: 202.5;Basal prostatic cells: 153.5;Basal respiratory cells: 125.9;Pancreatic endocrine cells: 195.2;Spermatocytes: 286.0;Urothelial cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 139.2;RPTEC TERT1: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" 0.1 0.0 0.0 1.9 0.0 0.0 20.2 0.0 0.0 2.7 0.0 8.0 8.4 5.4 1.7 14.2 3.4 14.8 0.6 0.0 0.0 68.3 0.1 45.3 0.0 0.0 0.0 0.0 3.3 32.2 1.8 5.5 0.0 5.1 7.4 0.0 3.9 8.9 80.0 2.6 6.3 0.3 0.0 0.0 18.7 0.1 0.0 0.0 4.7 64.5 3.0 44.9 6.5 0.0 14.5 0.2 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 139.2 0.1 0.8 0.1 0.0 28.7 0.0 45.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 31.4 0.0 0.1 0.4 0.1 0.0 0.0 0.0 3.8 4.3 0.0 0.0 0.0 9.0 0.0 0.0 10.9 0.0 269.9 45.7 0.0 0.1 0.1 43.7 0.0 1.6 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 153.8 202.5 0.0 0.0 10.5 153.5 125.9 46.1 0.0 35.5 31.0 38.7 10.0 60.4 71.7 0.0 13.6 0.5 30.3 0.0 57.5 89.4 9.6 0.7 2.6 0.0 0.0 0.3 105.4 7.0 2.6 37.8 24.4 3.8 0.0 1.1 1.0 2.2 0.0 0.2 11.6 24.4 0.3 0.4 48.3 2.8 2.2 1.8 0.0 2.0 1.7 0.0 0.5 0.1 195.2 25.6 1.2 0.0 57.3 10.0 1.9 17.7 0.1 0.0 5.7 3.8 286.0 3.0 42.2 8.5 4.7 2.1 0.0 12.4 129.3 ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "B-cells: 45.1;dendritic cells: 62.3;NK-cells: 134.9;Plasma cells: 115.9;T-cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 99 "Karpas-707: 4821.4;RPMI-8226: 3980.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" 1.6 1.4 1.7 20.0 1.8 15.5 1.9 1.7 2.2 2.7 2.0 9.7 11.7 1.6 2.8 6.4 2.9 3.9 0.8 1.5 2.0 4.7 5.3 6.6 29.2 2.3 1.8 0.7 1.2 0.7 1.3 0.5 2.0 1.7 9.5 1.0 4.1 2.3 0.7 11.9 17.3 2.4 1.9 30.0 8.2 0.6 2.8 8.6 3.1 0.6 26.5 6.2 2.9 2.1 0.1 0.0 0.0 0.3 0.1 0.7 1.4 0.5 0.0 0.0 0.5 0.0 2.1 44.5 0.8 0.0 0.0 9.4 0.0 0.3 0.0 16.5 0.0 1.5 0.0 0.0 0.0 1.0 18.5 1.0 1.8 0.2 0.1 0.6 0.0 2.2 0.4 4821.4 0.0 1.6 0.9 7.0 0.3 41.7 0.1 1.8 0.0 3980.8 0.0 1.2 1.9 0.6 0.1 1.8 0.5 0.0 0.8 10.4 0.0 0.3 0.6 0.9 0.0 8.9 17.9 3.8 3.8 2.6 1.6 80.7 5.6 97.7 52.0 1.4 38.2 28.1 51.8 63.0 44.5 29.8 44.5 44.4 1.5 23.7 0.4 11.9 71.8 17.3 1.7 1.8 1.7 2.2 1.5 2.0 2.3 1.8 2.0 1.9 2.8 2.1 1.0 3.2 5.5 1.3 45.1 2.2 0.3 1.7 3.4 0.1 1.3 1.0 0.5 2.8 1.3 7.3 4.2 0.1 62.3 0.6 7.9 0.3 0.0 1.2 0.4 0.9 0.0 2.1 0.0 0.5 0.1 1.3 2.6 2.4 29.2 0.1 0.4 2.2 13.3 0.0 0.1 0.5 0.0 3.7 10.3 0.3 0.0 17.3 7.2 1.9 13.3 7.0 134.9 0.0 0.5 0.9 1.7 0.0 115.9 0.2 0.0 7.6 0.2 0.8 0.0 1.0 8.2 0.2 1.4 3.3 3.7 0.1 62.5 0.1 1.2 1.4 ITGB8 ENSG00000105855 "Integrin subunit beta 8" P26012 7 20330702-20415754 "Cancer-related genes, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.9;choroid plexus: 39.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 376.2;Glandular and luminal cells: 551.9;Oligodendrocyte precursor cells: 192.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 133 "basophil: 16.5" "Lineage enriched" "Detected in single" 133 "granulocytes: 16.5" "Cell line enhanced" "Detected in many" "AF22: 44.3;EFO-21: 54.6;RPTEC TERT1: 88.1;WM-115: 127.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027796, HPA027797" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA027796: AB_10600299, HPA027797: AB_10600879" "unprognostic (8.32e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (3.37e-3)" "unprognostic (5.63e-2)" "unprognostic (3.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.46e-1)" "unprognostic (4.36e-2)" "unprognostic (1.75e-2)" "unprognostic (2.49e-3)" "unprognostic (8.47e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.63e-2)" "unprognostic (6.92e-3)" 3.8 2.6 25.7 4.2 41.8 0.3 9.6 53.9 19.2 15.4 39.4 3.7 3.2 7.7 14.0 6.4 7.5 8.7 2.9 19.5 37.5 21.6 0.8 2.4 0.5 38.9 48.4 4.7 13.3 5.1 5.4 5.2 42.7 6.7 2.8 4.6 13.6 9.0 0.2 6.3 4.2 3.0 39.7 0.0 4.2 6.5 35.6 0.8 2.1 0.9 6.9 7.2 9.0 48.6 28.2 1.1 44.3 5.6 3.7 15.2 0.0 0.1 0.5 0.2 1.5 0.3 6.9 0.0 54.6 2.0 1.7 30.1 1.9 4.5 0.5 0.0 0.7 0.0 23.1 0.0 1.8 0.0 0.1 1.8 12.6 0.5 2.4 27.1 2.4 0.0 0.0 8.3 0.8 0.1 0.0 0.0 3.3 0.4 4.8 0.0 3.7 0.0 88.1 2.5 0.7 1.9 8.6 0.2 23.5 0.8 0.7 0.1 3.0 11.2 7.1 3.2 5.8 10.2 0.1 0.0 2.7 0.0 127.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 25.7 41.8 53.9 19.2 19.5 37.5 38.9 48.4 42.7 39.7 35.6 48.6 0.7 12.8 4.8 106.4 2.5 33.1 117.2 39.4 34.7 13.3 26.3 18.7 3.0 38.6 57.9 38.6 0.0 20.0 0.4 5.0 7.9 26.3 3.0 376.2 150.6 5.2 34.0 0.0 28.1 17.4 1.2 15.5 7.7 551.9 1.3 0.9 1.4 0.2 3.3 1.7 8.2 7.4 34.6 1.0 4.7 6.5 44.1 9.8 3.6 4.7 31.6 24.3 0.0 192.0 119.2 35.8 6.1 44.8 2.0 149.7 14.5 76.7 100.1 1.4 0.0 4.8 7.0 1.4 1.1 34.6 12.4 4.9 5.5 1.9 9.6 150.7 ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "liver: 1863.4" "Group enriched" "Detected in many" 5 "Early spermatids: 119.2;Hepatocytes: 134.6;Late spermatids: 126.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.4;JURKAT: 2.0;U-266/70: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" NA NA 3060000 58000000000 "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB072872: AB_2665724, HPA001835: AB_1079432, HPA003948: AB_1079433" "unprognostic (6.08e-2)" "unprognostic (4.45e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.96e-1)" "unprognostic (5.86e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-14)" "unprognostic (1.71e-3)" "unprognostic (2.96e-2)" "unprognostic (1.52e-1)" "unprognostic (4.21e-5)" 4.2 18.5 4.1 1.2 4.2 10.0 3.0 3.7 5.0 4.2 3.5 3.6 1.0 2.9 1.7 1.4 3.8 1.1 3.2 3.9 3.6 5.4 1863.4 4.9 1.7 3.9 3.8 2.4 48.9 0.1 4.3 0.7 3.9 4.0 1.0 3.3 2.1 1.8 40.3 2.5 3.4 1.5 3.6 7.4 3.9 1.8 3.8 2.2 5.2 2.8 1.2 5.3 3.3 3.9 0.0 0.1 0.4 0.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.2 0.1 0.4 0.0 0.0 0.2 2.4 0.1 1.0 0.0 1.2 0.4 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 0.3 0.8 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.8 0.3 0.0 0.2 0.3 0.0 0.4 0.3 0.0 0.1 0.4 0.5 0.3 0.1 0.0 0.4 0.4 0.0 3.0 1.4 0.2 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 4.1 4.2 3.7 5.0 3.9 3.6 3.9 3.8 3.9 3.6 3.8 3.9 0.7 0.0 1.1 22.5 0.9 0.8 0.3 0.3 0.0 10.0 0.6 1.3 1.1 2.8 0.8 0.0 12.5 0.0 0.4 0.1 0.0 0.3 119.2 0.7 0.7 0.8 0.0 8.4 11.6 2.6 0.0 0.6 1.1 0.4 0.0 2.7 2.5 134.6 0.5 5.0 8.6 0.2 0.0 2.2 1.0 126.5 1.2 1.3 0.0 5.6 1.9 2.3 2.1 3.0 3.1 2.3 0.5 1.9 0.7 0.2 0.0 0.3 0.3 6.0 6.6 6.2 2.4 1.3 1.5 0.0 0.3 0.3 1.2 3.2 0.1 0.1 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 ITPKB "IP3-3KB, IP3KB" ENSG00000143772 "Inositol-trisphosphate 3-kinase B" P27987 1 226631690-226739323 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 211.8;choroid plexus: 123.3" "Cell type enhanced" "Detected in many" "Adipocytes: 70.5;Astrocytes: 225.3;Microglial cells: 58.1;Oligodendrocytes: 110.6" "Cancer enhanced" "Detected in all" "melanoma: 44.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-MEL-30: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030273, HPA072923" Enhanced Approved Nucleoplasm NA NA 39000 "Cluster 49: Eosinophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA030273: AB_10601127, HPA072923: AB_2686558" "unprognostic (4.54e-2)" "unprognostic (3.85e-2)" "unprognostic (8.41e-3)" "unprognostic (9.37e-3)" "unprognostic (1.53e-1)" "prognostic favorable (1.72e-5)" "unprognostic (1.24e-1)" "prognostic favorable (6.65e-4)" "unprognostic (2.29e-1)" "unprognostic (9.57e-2)" "unprognostic (1.41e-2)" "unprognostic (1.75e-2)" "unprognostic (3.23e-3)" "unprognostic (2.90e-2)" "unprognostic (7.46e-2)" "unprognostic (6.54e-3)" "unprognostic (7.87e-2)" 29.6 4.5 148.6 15.6 205.6 19.0 19.6 152.0 104.8 28.0 123.3 45.3 6.6 48.8 17.0 14.0 27.0 10.0 16.2 109.0 149.5 15.1 3.2 22.5 29.0 211.8 188.0 9.5 5.8 7.1 6.8 15.9 169.1 14.5 6.7 0.6 30.2 22.7 12.4 19.4 24.9 31.7 154.6 23.5 21.2 3.7 207.6 33.2 8.3 12.3 20.3 38.6 15.6 133.7 4.7 5.0 7.9 9.1 6.1 3.9 2.1 1.2 5.5 2.5 5.7 0.7 5.8 21.6 7.4 1.2 0.5 6.8 10.1 4.1 1.2 3.0 6.9 9.6 5.5 0.0 2.3 8.8 16.4 4.4 5.9 2.8 2.5 6.9 17.2 10.8 0.1 2.9 0.3 4.5 16.7 12.1 17.3 3.5 8.0 6.4 14.2 4.8 18.2 7.5 4.6 6.0 3.8 2.8 47.2 7.7 11.7 10.1 12.0 3.2 2.4 2.9 7.6 0.2 8.0 25.8 0.8 8.0 12.1 0.9 0.9 5.4 2.6 1.3 2.3 1.2 3.2 2.7 0.6 1.8 4.7 3.5 3.4 2.1 2.5 0.5 1.9 2.0 148.6 205.6 152.0 104.8 109.0 149.5 211.8 188.0 169.1 154.6 207.6 133.7 70.5 0.0 7.4 225.3 16.0 12.2 4.8 3.1 7.4 0.3 7.0 5.3 8.5 1.5 4.5 7.3 0.0 0.6 28.9 1.2 3.9 2.2 2.8 4.7 6.8 42.2 4.2 5.2 2.4 2.4 2.3 8.9 3.6 4.5 10.1 21.8 27.8 1.0 19.8 0.0 6.9 2.8 2.0 16.0 38.0 22.9 7.2 14.4 19.6 58.1 10.2 1.2 28.8 10.6 110.6 2.7 3.7 9.4 11.8 5.1 2.0 0.6 2.6 0.1 0.0 5.9 16.3 0.9 4.7 5.3 10.1 0.4 35.2 3.7 3.1 2.7 JAK1 "JAK1A, JAK1B, JTK3" ENSG00000162434 "Janus kinase 1" P23458 1 64833229-65067754 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 700.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 336.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013088 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "CAB013088: " "prognostic favorable (9.63e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.81e-4)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (8.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.66e-2)" "unprognostic (8.84e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "unprognostic (3.51e-1)" 99.6 38.2 44.8 73.9 42.6 51.4 60.7 46.7 45.4 58.2 61.7 50.5 33.9 56.7 60.8 38.7 40.7 64.2 49.5 46.0 53.9 55.4 86.6 62.1 110.1 56.0 47.0 77.1 46.7 55.0 35.6 57.0 49.1 42.2 54.5 41.7 34.2 55.2 83.4 79.2 50.8 64.2 44.0 88.3 49.5 46.8 59.8 103.8 45.0 118.6 101.7 81.2 39.3 45.5 50.4 66.2 27.7 3.0 336.8 177.2 35.1 76.3 116.1 64.6 75.7 21.4 27.7 76.5 59.1 142.8 118.7 27.8 19.4 63.6 93.8 102.7 29.5 104.0 32.1 56.2 126.6 40.2 68.4 159.9 92.6 97.2 103.0 78.4 208.7 37.0 37.9 78.9 80.1 31.2 22.3 39.6 18.6 65.3 37.4 30.5 77.8 28.5 213.8 84.9 19.8 57.9 107.4 51.6 52.9 56.6 104.3 28.6 180.8 74.7 34.1 174.2 42.0 47.7 23.6 60.4 70.5 57.9 34.1 162.4 52.1 146.8 94.0 66.3 105.7 89.1 90.2 100.7 69.4 73.1 97.0 80.6 177.9 305.4 76.2 55.0 117.1 130.8 44.8 42.6 46.7 45.4 46.0 53.9 56.0 47.0 49.1 44.0 59.8 45.5 211.2 51.3 94.9 62.3 219.8 116.6 150.7 91.3 78.0 37.0 66.2 71.6 112.8 87.2 84.2 112.2 22.9 9.0 345.0 89.2 43.0 171.3 125.2 90.1 167.0 183.0 66.4 52.8 59.6 213.8 105.2 131.9 91.3 151.2 57.0 48.7 174.2 91.4 58.5 21.9 85.3 62.0 69.2 160.2 148.9 101.7 96.0 177.9 49.8 80.6 234.8 53.5 700.3 61.3 42.7 217.5 58.6 84.7 175.2 183.8 53.7 79.0 61.9 38.6 164.3 70.6 191.8 40.8 53.1 71.2 166.1 12.2 256.0 95.7 47.6 200.1 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.4;Inhibitory neurons: 122.3;Microglial cells: 106.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 132.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 132.5" "Group enriched" "Detected in many" 5 "ASC diff: 42.2;HDLM-2: 75.0;HEL: 154.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 15.6 7.6 3.2 19.2 3.7 21.7 8.9 6.3 9.1 8.5 1.1 6.7 6.5 11.3 8.6 8.8 8.0 10.5 24.5 2.7 3.1 6.8 4.5 10.9 18.2 3.3 1.8 11.5 3.8 6.5 2.9 11.0 2.0 6.8 6.5 12.8 4.0 6.2 9.8 11.2 7.7 9.5 3.5 17.6 13.4 9.8 1.7 7.5 4.8 8.9 12.7 11.7 9.1 3.9 6.8 3.7 3.7 6.3 42.2 12.4 1.1 9.1 8.6 7.2 4.6 1.2 2.0 0.3 2.1 5.4 5.4 2.3 4.4 5.1 4.9 75.0 1.4 154.7 7.6 1.7 10.0 10.5 7.1 9.5 2.1 2.8 4.5 7.6 6.6 5.1 10.9 17.4 11.6 2.2 2.9 12.8 3.3 3.3 4.3 5.1 8.2 2.2 4.7 3.5 4.2 2.4 2.6 3.5 2.8 3.6 2.0 15.4 13.1 10.2 3.6 10.7 6.4 3.1 6.4 1.5 13.6 4.7 5.3 132.5 20.5 38.2 5.6 20.1 4.5 5.6 4.1 3.1 26.5 4.9 2.2 2.8 19.2 9.6 16.4 9.7 4.5 7.7 3.2 3.7 6.3 9.1 2.7 3.1 3.3 1.8 2.0 3.5 1.7 3.9 14.3 16.0 7.9 31.6 12.9 9.7 3.3 4.9 10.8 8.0 5.2 3.4 30.0 0.0 6.7 7.3 8.4 1.9 13.9 11.7 1.9 3.3 8.6 5.1 11.2 9.4 3.0 19.8 93.4 3.9 0.9 8.9 38.7 5.6 14.0 11.4 4.6 1.9 14.2 8.4 122.3 4.5 0.0 33.6 28.8 7.1 23.6 38.9 5.4 106.8 49.5 12.6 8.2 69.9 42.3 7.0 20.9 33.4 10.7 3.0 3.9 3.3 7.1 11.2 0.0 9.7 12.5 15.0 5.5 11.6 8.4 3.4 10.4 5.1 4.1 4.5 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 JKAMP "C14orf100, CDA06, HSPC213, HSPC327, JAMP" ENSG00000050130 "JNK1/MAPK8 associated membrane protein" Q9P055 14 59484443-59505410 "Cancer-related genes, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 174.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031172, HPA071650" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA031172: AB_10670563, HPA071650: AB_2686429" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (4.95e-2)" "unprognostic (5.88e-2)" "unprognostic (2.54e-1)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.09e-6)" "unprognostic (2.68e-1)" "unprognostic (3.52e-1)" "unprognostic (1.16e-1)" "unprognostic (3.09e-1)" "unprognostic (3.14e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.36e-1)" "unprognostic (1.73e-1)" 25.9 34.9 23.6 17.7 26.5 22.9 32.5 29.5 30.3 23.0 34.2 29.6 17.3 30.5 26.4 17.8 31.2 30.8 25.9 22.9 30.2 44.5 34.0 30.7 25.2 30.1 29.8 25.8 20.7 56.6 28.6 33.8 31.3 29.9 29.5 34.7 25.4 27.0 17.1 17.9 24.0 27.7 28.7 23.0 24.4 30.4 26.1 22.1 34.6 21.1 20.7 26.4 16.2 32.0 54.8 68.0 57.3 46.8 40.9 59.0 42.8 85.9 76.6 52.6 62.9 21.8 108.1 27.7 75.6 85.5 55.3 40.0 41.2 52.8 72.1 82.8 24.0 30.3 38.5 42.3 56.0 45.6 53.6 60.9 56.6 45.9 32.6 82.1 55.7 35.8 25.4 54.9 100.7 54.1 25.6 37.8 31.2 45.9 60.4 31.4 73.6 27.9 92.1 59.3 23.7 40.9 82.8 68.4 45.1 40.0 66.4 32.3 72.4 54.9 65.6 53.0 58.0 21.7 45.5 32.7 80.7 33.2 68.0 86.3 59.3 82.3 34.4 74.8 34.3 36.1 37.0 37.0 51.9 34.1 38.9 36.5 89.4 50.2 83.0 70.5 47.0 57.8 23.6 26.5 29.5 30.3 22.9 30.2 30.1 29.8 31.3 28.7 26.1 32.0 25.5 22.4 31.2 29.7 23.6 30.0 32.8 132.9 54.1 30.3 31.6 27.1 10.2 41.5 66.3 46.0 18.8 64.2 42.0 27.4 7.9 45.4 174.5 43.3 31.7 26.9 31.2 40.8 30.3 54.8 64.8 37.4 27.5 20.9 34.9 28.0 26.4 41.9 57.8 28.6 26.8 26.7 89.5 60.3 31.4 61.2 35.4 40.4 48.0 19.7 34.2 40.1 29.9 28.1 34.5 51.4 21.3 31.6 50.2 26.3 22.4 53.0 110.6 30.3 13.1 27.5 58.8 85.1 41.1 30.7 29.1 29.8 27.6 30.3 24.6 20.9 JTB "hJT, PAR" ENSG00000143543 "Jumping translocation breakpoint" O76095 1 153974269-153977674 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006514 Approved Uncertain Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA006514: AB_1079164" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" "unprognostic (8.01e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.40e-1)" "unprognostic (5.66e-3)" "unprognostic (8.62e-3)" "unprognostic (5.60e-2)" "prognostic favorable (7.87e-4)" "unprognostic (1.00e-3)" "unprognostic (8.16e-2)" "prognostic unfavorable (6.65e-9)" "unprognostic (1.36e-1)" "unprognostic (4.25e-1)" "unprognostic (5.48e-2)" "unprognostic (2.58e-3)" 105.6 119.8 121.1 60.4 125.1 127.0 103.0 122.3 153.9 99.8 149.0 117.8 89.5 89.8 96.3 110.8 91.8 53.7 121.0 120.8 122.2 135.4 207.1 110.2 80.4 125.4 122.2 98.4 232.2 93.9 185.9 68.0 121.5 131.0 86.7 49.8 162.0 68.0 166.5 99.8 115.3 50.1 123.3 136.9 164.8 46.6 126.6 77.7 120.5 82.7 80.2 96.3 89.4 123.4 206.3 139.4 57.9 108.0 189.0 116.2 163.5 144.6 142.3 95.9 96.0 135.3 166.7 193.7 198.7 171.8 59.1 181.0 151.0 113.2 78.1 180.5 296.0 112.5 158.4 139.0 198.1 221.4 165.7 110.4 210.4 101.1 119.1 131.0 115.4 223.7 169.3 139.2 68.4 359.6 161.5 280.5 125.8 402.1 239.1 163.9 79.3 393.1 123.7 110.9 158.4 158.8 115.3 332.7 208.4 107.4 209.1 316.4 89.6 46.5 80.4 144.4 189.0 201.8 244.7 211.3 114.5 209.6 103.7 98.7 119.5 173.2 74.7 86.4 90.9 143.5 104.0 118.7 88.9 139.9 107.0 85.6 104.9 85.3 96.5 147.4 98.5 97.7 121.1 125.1 122.3 153.9 120.8 122.2 125.4 122.2 121.5 123.3 126.6 123.4 127.7 80.1 101.1 15.7 184.3 156.8 177.4 227.5 104.7 56.6 253.4 207.3 96.5 213.1 171.4 99.3 22.9 308.8 237.3 273.4 258.2 251.9 7.1 145.0 95.3 120.4 212.0 178.8 26.3 411.8 405.0 155.6 149.9 125.9 82.5 113.2 125.7 341.3 289.1 57.2 24.0 423.4 213.6 235.8 185.8 20.1 151.6 176.3 170.7 19.7 207.9 140.4 257.5 19.6 29.1 274.1 302.2 123.4 344.8 346.0 368.2 274.1 138.2 60.2 105.2 105.3 114.0 58.9 71.5 173.4 190.2 289.5 173.6 136.6 315.2 304.0 JUN "AP-1, c-Jun" ENSG00000177606 "Jun proto-oncogene, AP-1 transcription factor subunit" P05412 1 58776845-58784048 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 295.6" "Low region specificity" "Detected in all" "CAB003801, CAB007780, HPA031174, HPA059474" Enhanced Enhanced Nucleoplasm Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB003801: AB_365485, CAB007780: AB_562268, HPA031174: , HPA059474: AB_2684030" "unprognostic (2.06e-2)" "unprognostic (1.76e-2)" "unprognostic (1.34e-1)" "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (1.70e-1)" "unprognostic (4.11e-2)" "unprognostic (5.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "unprognostic (2.82e-1)" "unprognostic (5.15e-2)" "unprognostic (1.45e-1)" "unprognostic (2.83e-1)" "unprognostic (2.37e-1)" "unprognostic (2.81e-3)" 331.1 92.7 34.4 36.3 37.0 129.1 308.2 41.6 38.1 172.0 28.0 154.7 34.7 116.4 15.8 100.2 314.1 89.6 158.4 39.1 37.2 94.0 205.2 202.8 52.1 32.7 30.7 197.0 192.2 59.8 75.0 40.1 30.5 153.4 55.0 29.7 154.5 71.7 114.3 286.6 79.1 113.3 34.3 62.0 239.5 20.2 33.8 71.5 189.5 158.8 5.4 156.4 164.5 36.9 49.8 2.8 22.4 2.6 35.3 40.0 0.2 69.4 27.0 57.1 34.3 10.1 3.5 1.7 23.8 57.4 133.6 12.9 2.0 27.7 40.6 29.8 128.9 0.5 1.9 16.9 29.4 5.3 10.2 42.0 74.0 78.1 34.0 27.7 47.2 2.4 15.6 29.6 24.9 8.0 2.5 32.5 13.5 34.6 32.2 1.1 295.6 7.0 60.7 5.8 43.7 12.8 49.9 62.3 26.4 24.5 17.2 3.0 61.6 127.5 37.3 35.3 96.8 37.9 9.8 4.4 133.9 8.4 35.2 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.0 34.4 37.0 41.6 38.1 39.1 37.2 32.7 30.7 30.5 34.3 33.8 36.9 2721.4 538.5 543.8 187.7 1018.8 1235.5 2850.5 772.6 2825.1 103.4 1647.1 2067.3 1487.5 1315.4 449.3 104.8 262.7 675.8 651.1 1653.6 50.9 987.0 49.3 1337.1 2845.2 1443.8 1497.4 174.3 12.2 516.4 93.9 2730.7 2663.1 1822.2 541.9 333.4 737.2 158.6 650.5 87.5 4.9 1909.1 836.2 584.9 632.0 48.2 1227.4 1034.9 757.7 65.6 140.1 1234.2 8.2 17.6 10.0 562.8 1529.6 258.8 1540.3 1489.1 1654.1 48.6 216.3 453.5 1538.3 1892.9 2392.5 17.4 20.9 2146.3 964.4 415.6 1065.5 846.5 1199.5 545.7 JUND AP-1 ENSG00000130522 "JunD proto-oncogene, AP-1 transcription factor subunit" P17535 19 18279694-18281622 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 2129.8;dendritic cells: 1844.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005268, HPA063029" Supported Supported Nucleoplasm No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB005268: AB_2130177, HPA063029: AB_2684925" "prognostic favorable (6.15e-5)" "unprognostic (4.18e-3)" "unprognostic (8.89e-2)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (6.39e-2)" "unprognostic (1.63e-2)" "unprognostic (6.35e-2)" "unprognostic (3.48e-2)" "unprognostic (2.00e-1)" "unprognostic (3.37e-3)" "unprognostic (4.09e-2)" "unprognostic (3.35e-2)" "unprognostic (1.22e-1)" "unprognostic (3.99e-1)" "unprognostic (5.37e-2)" "unprognostic (1.49e-1)" 296.3 189.3 190.3 38.9 201.6 429.1 257.3 172.1 208.5 159.7 153.1 185.2 62.9 186.6 37.5 118.3 291.4 30.0 210.6 187.5 192.5 148.8 211.8 227.3 28.8 261.3 213.2 424.2 178.4 40.4 256.4 45.1 180.9 159.1 33.0 25.7 112.7 33.8 81.0 287.7 161.3 57.5 182.5 100.5 201.4 97.4 180.4 58.2 154.8 37.1 15.9 129.5 147.7 263.8 84.2 35.3 33.3 37.9 25.9 28.8 150.5 35.0 40.8 19.2 25.4 38.3 72.9 42.1 39.4 34.8 31.1 46.1 8.2 8.3 9.5 84.6 75.9 62.7 30.3 84.9 58.6 29.5 81.4 27.8 33.7 20.0 25.9 44.5 15.3 18.8 86.5 119.8 5.2 113.6 89.9 92.5 69.7 22.7 50.6 32.7 20.9 94.0 27.8 13.1 184.2 75.1 41.7 45.4 122.0 37.5 38.6 43.9 54.7 11.8 54.8 74.4 20.9 171.3 73.8 36.3 41.5 44.7 27.9 10.5 6.5 6.8 4.9 8.2 3.8 8.4 6.4 4.5 4.9 8.7 4.5 5.0 19.7 4.8 8.3 11.3 5.7 2.4 190.3 201.6 172.1 208.5 187.5 192.5 261.3 213.2 180.9 182.5 180.4 263.8 2129.8 179.5 386.7 104.5 1176.8 317.1 400.4 76.0 188.4 129.8 1147.5 1419.1 158.8 291.7 84.4 257.5 79.2 78.5 1844.7 810.5 31.3 96.5 80.8 1026.0 1289.3 468.1 568.8 78.3 51.6 140.8 112.9 950.9 336.4 1561.4 257.7 514.1 338.4 436.1 100.1 139.7 41.0 569.6 67.1 332.7 506.0 59.2 123.3 847.7 249.1 65.6 91.7 625.2 27.8 44.7 132.0 154.4 464.2 88.8 734.5 253.6 538.1 65.4 90.4 174.3 131.5 1064.7 798.4 11.8 22.7 172.0 394.1 164.3 1158.2 448.7 297.4 232.7 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124080023-124726325 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1434.2;Inhibitory neurons: 480.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "CACO-2: 57.4;HEL: 35.3;OE19: 20.1;SH-SY5Y: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 83000 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" 9.4 6.3 15.0 2.2 23.4 0.3 6.7 0.0 31.3 9.1 4.9 2.0 2.5 7.7 1.9 9.5 4.6 2.9 12.8 21.3 3.4 3.8 5.8 4.4 0.9 0.0 6.6 3.1 8.8 3.5 4.1 4.2 0.0 2.8 1.8 4.5 2.8 4.9 27.2 2.0 2.0 6.2 0.0 8.5 12.1 2.6 10.7 0.5 5.1 19.3 1.6 2.6 6.0 20.9 0.7 1.1 6.2 1.3 0.9 0.2 8.1 2.5 1.5 2.4 1.1 57.4 4.5 0.2 0.8 6.4 3.9 0.4 1.4 0.0 2.0 0.0 0.7 35.3 0.4 8.9 0.1 0.0 0.0 0.4 0.0 0.5 0.1 2.6 2.9 0.1 8.3 0.2 0.7 4.2 0.0 0.0 3.5 20.1 5.4 1.8 2.8 0.0 0.2 0.5 2.1 15.9 0.7 0.5 0.5 6.0 1.2 0.1 14.4 7.0 2.8 1.0 1.1 0.0 0.6 0.0 0.8 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.7 0.2 0.2 0.0 0.0 0.0 1.6 0.4 15.0 23.4 0.0 31.3 21.3 3.4 0.0 6.6 0.0 0.0 10.7 20.9 56.2 3.2 3.9 191.3 0.6 1.7 1.5 0.3 0.6 61.2 6.1 7.1 32.1 18.6 0.5 16.5 6.2 8.0 2.5 40.5 1.9 5.0 57.0 15.0 18.8 23.2 9.6 5.3 1434.2 8.4 1.7 5.9 29.0 7.4 3.8 4.4 45.3 21.7 1.0 0.0 480.8 16.4 0.0 1.6 1.1 64.0 3.7 5.3 3.6 48.7 0.0 4.7 8.2 162.3 63.1 4.4 21.0 33.1 0.3 2.6 34.8 3.6 8.4 2.7 19.7 8.8 21.8 5.2 2.6 4.9 1.1 14.2 1.0 17.5 12.3 1.6 KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040446-20154404 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 165.2;Oligodendrocyte precursor cells: 418.2;Oligodendrocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002470, CAB004526, HPA055839, HPA073897" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "CAB004526: AB_2128417, HPA002470: , HPA055839: AB_2682938, HPA073897: " "unprognostic (2.91e-2)" "unprognostic (6.85e-3)" "unprognostic (9.05e-2)" "unprognostic (2.25e-1)" "unprognostic (2.66e-2)" "unprognostic (3.01e-3)" "unprognostic (2.44e-1)" "unprognostic (3.83e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-3)" "unprognostic (7.13e-2)" "unprognostic (7.03e-2)" "unprognostic (2.26e-2)" "unprognostic (1.59e-1)" "unprognostic (5.16e-2)" "unprognostic (4.63e-2)" 17.9 9.9 38.7 15.4 46.5 48.0 10.3 39.1 40.3 14.9 33.8 13.8 17.7 12.3 8.1 27.4 11.7 12.6 35.9 34.4 42.2 16.6 39.3 16.2 22.4 41.7 44.9 27.7 18.7 51.0 10.2 13.7 43.0 14.5 12.5 33.9 37.6 13.0 60.2 14.3 21.5 13.6 37.1 19.8 13.9 2.7 42.2 23.6 14.4 56.1 20.1 11.9 15.1 45.1 2.7 6.9 3.8 6.2 15.1 14.2 8.8 8.8 13.0 9.1 13.3 2.1 4.5 24.0 3.6 16.7 11.5 2.0 9.4 2.8 7.6 21.8 9.0 21.0 10.7 0.7 7.1 3.2 26.2 6.1 5.0 7.9 5.1 16.0 8.8 5.8 13.7 32.9 13.0 3.3 7.0 6.4 1.6 6.7 6.8 9.1 7.1 5.1 12.4 14.2 1.9 4.1 4.9 7.9 30.5 5.9 8.2 14.2 8.5 15.3 6.1 5.8 10.1 12.3 27.6 5.7 13.9 13.8 33.0 0.6 0.4 1.3 1.5 0.7 1.5 0.4 1.3 1.1 0.4 0.8 0.4 0.8 2.4 0.5 0.5 1.2 2.2 0.3 38.7 46.5 39.1 40.3 34.4 42.2 41.7 44.9 43.0 37.1 42.2 45.1 15.5 32.1 20.8 165.2 11.9 8.5 11.3 2.2 3.4 14.6 5.5 5.0 64.1 4.3 10.4 5.5 4.2 7.3 19.5 16.6 11.7 3.8 3.8 6.4 5.7 14.6 11.5 52.2 22.4 4.4 1.1 11.7 3.6 13.1 10.8 12.3 20.7 33.6 7.7 15.2 32.1 7.3 4.1 22.8 23.3 1.8 6.5 16.0 17.8 52.5 11.1 14.8 14.4 418.2 175.4 3.3 2.4 5.3 19.9 7.1 24.7 6.2 12.7 11.9 6.6 25.2 9.0 0.8 1.4 10.0 12.9 9.9 23.5 2.9 3.8 8.0 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 14.4 7.1 8.6 15.4 12.7 38.2 12.3 20.1 10.5 13.7 9.7 10.2 9.6 15.6 8.6 13.4 12.0 11.2 9.1 9.1 12.8 9.1 10.0 16.7 16.8 12.7 12.4 21.5 11.7 18.0 6.7 14.9 12.9 11.0 10.6 18.1 9.6 9.7 13.1 16.6 12.1 13.5 8.2 15.7 11.3 11.4 10.1 27.0 14.2 16.0 17.2 12.0 10.7 16.7 19.6 23.2 34.8 21.8 17.8 20.3 9.8 15.4 20.6 17.9 14.2 16.3 11.5 33.4 13.4 19.0 19.5 17.3 27.3 18.6 23.2 16.1 14.4 60.4 14.2 10.3 14.8 27.3 23.6 17.1 19.1 20.4 24.8 14.5 18.8 29.7 36.6 24.2 16.0 10.4 59.9 9.4 12.8 20.4 8.1 37.7 39.1 9.9 11.0 27.1 17.6 16.7 15.8 12.4 13.8 15.8 26.3 12.9 25.5 21.6 15.3 21.1 15.5 16.8 22.1 33.8 12.6 14.1 17.3 2.5 0.8 1.8 1.6 0.9 1.6 1.4 1.6 2.1 0.6 1.6 1.9 1.8 5.1 1.9 0.9 1.1 1.9 1.2 8.6 12.7 20.1 10.5 9.1 12.8 12.7 12.4 12.9 8.2 10.1 16.7 87.5 35.3 34.9 64.0 54.0 50.3 24.2 15.5 18.2 54.8 31.7 25.5 23.7 18.6 25.3 12.9 54.2 14.4 61.5 23.2 3.9 14.2 2.6 30.3 47.5 56.7 24.7 31.2 62.8 11.8 17.0 32.4 21.4 44.8 35.4 31.9 43.5 25.3 17.0 58.9 76.6 24.9 10.2 44.2 34.5 4.8 28.3 43.7 23.2 120.9 30.3 27.9 61.8 93.5 129.2 15.7 20.2 23.0 38.7 30.7 22.9 10.6 22.8 44.9 19.7 49.3 34.6 37.8 37.0 23.0 61.2 21.1 61.4 19.7 19.3 27.2 KAT6B "Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B" ENSG00000156650 "Lysine acetyltransferase 6B" Q8WYB5 10 74824927-75032624 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006104 Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "HPA006104: AB_1079445" "unprognostic (4.17e-1)" "unprognostic (1.98e-1)" "unprognostic (1.82e-1)" "unprognostic (2.32e-2)" "unprognostic (7.83e-2)" "unprognostic (2.85e-2)" "unprognostic (3.56e-1)" "unprognostic (2.62e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-1)" "unprognostic (9.47e-2)" "unprognostic (8.78e-2)" "prognostic favorable (4.82e-4)" "unprognostic (2.52e-1)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (3.15e-1)" 7.6 6.3 5.0 3.1 5.6 8.8 7.3 5.6 5.3 10.5 2.0 9.6 3.2 9.2 5.2 6.9 8.3 3.8 7.5 5.7 4.0 4.3 4.6 6.5 4.4 3.1 3.5 12.2 8.6 10.5 7.4 4.4 3.0 6.5 4.1 6.4 7.3 4.3 11.8 8.0 8.1 6.0 3.0 5.4 9.3 7.8 5.6 9.8 7.3 6.0 4.1 9.1 8.9 4.9 4.7 4.4 8.0 6.9 6.2 9.2 4.1 4.1 7.5 3.4 3.6 3.4 5.3 9.8 2.1 7.1 3.5 3.8 4.2 3.3 5.6 4.2 6.8 3.6 3.9 4.5 4.5 8.6 2.4 5.9 5.3 4.5 6.9 10.5 3.8 7.7 3.9 9.0 4.2 4.7 8.2 4.3 5.0 4.9 25.7 12.7 4.3 2.4 2.3 2.3 4.2 6.9 4.1 7.4 3.7 2.8 4.5 3.2 4.7 4.6 5.5 3.1 3.8 6.4 8.1 6.4 5.0 8.9 1.3 1.7 1.3 1.6 2.3 1.0 2.6 2.2 1.9 2.1 1.1 2.8 2.9 2.6 1.8 4.4 1.1 1.7 1.7 1.0 5.0 5.6 5.6 5.3 5.7 4.0 3.1 3.5 3.0 3.0 5.6 4.9 34.5 44.8 53.7 90.1 48.1 19.9 20.8 16.3 74.6 52.8 36.7 27.3 53.9 12.8 29.3 9.2 68.8 10.4 51.8 22.5 9.8 12.7 6.2 41.1 72.7 24.9 23.8 32.0 130.2 18.0 10.6 44.4 57.6 50.8 41.7 68.0 18.9 16.0 11.0 43.7 131.2 21.7 12.2 12.3 15.0 8.3 42.3 24.1 14.2 41.2 13.6 45.5 42.2 101.0 92.1 10.5 19.4 40.3 62.5 21.0 17.8 10.2 28.6 52.5 26.3 55.3 44.1 33.1 32.2 46.6 17.5 22.7 59.7 27.1 17.5 23.5 KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSG00000120457 "Potassium inwardly rectifying channel subfamily J member 5" P48544 11 128891356-128921163 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 64.3;pancreas: 20.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 48.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "HBEC3-KT: 13.3" "Group enriched" "Detected in many" 6 "basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6" "Low region specificity" "Detected in all" "HPA014722, HPA017353, CAB022569" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "CAB022569: , HPA014722: AB_1852133, HPA017353: AB_1852135" "unprognostic (2.01e-1)" "unprognostic (2.43e-3)" "unprognostic (2.56e-3)" "unprognostic (5.81e-2)" "unprognostic (4.24e-2)" "unprognostic (3.60e-2)" "unprognostic (2.90e-1)" "unprognostic (3.54e-2)" "unprognostic (6.83e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.81e-2)" "unprognostic (6.82e-2)" "unprognostic (9.49e-2)" "unprognostic (1.88e-2)" "unprognostic (2.23e-2)" 1.5 64.3 1.2 0.6 0.9 0.4 0.9 0.6 2.0 1.3 0.2 0.8 0.8 0.3 0.9 1.0 0.9 2.2 8.5 0.7 3.2 5.4 0.4 5.9 1.6 3.7 1.7 0.9 20.4 1.3 11.9 7.3 2.7 1.3 0.7 1.0 0.9 9.6 0.4 0.4 0.5 0.6 1.7 13.6 2.3 1.1 7.9 5.8 0.5 0.4 0.5 1.5 0.4 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.3 13.3 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 1.2 0.9 0.6 2.0 0.7 3.2 3.7 1.7 2.7 1.7 7.9 3.9 0.2 0.0 10.0 0.3 0.2 1.5 2.2 4.7 0.0 2.7 0.2 1.4 7.6 0.0 0.3 1.8 0.0 0.8 0.1 0.0 0.0 0.1 2.3 0.2 0.2 0.6 0.0 0.0 0.2 3.9 0.7 1.1 0.0 0.3 0.0 0.2 0.4 0.1 48.3 1.7 3.1 0.0 0.0 2.2 2.9 7.8 0.9 10.9 3.6 3.7 1.2 0.3 3.1 0.5 0.1 0.8 0.0 0.7 0.3 0.6 0.0 0.1 0.3 1.4 0.0 0.9 0.2 0.9 0.5 0.5 1.7 1.2 0.6 2.3 0.0 0.6 KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear bodies" Cytosol "HPA006201: AB_1079160" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (5.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.77e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (7.69e-2)" 8.1 8.7 5.8 11.4 8.3 45.5 11.1 11.6 8.5 8.6 10.0 8.2 7.2 9.7 7.1 8.9 7.6 8.0 5.2 6.2 6.5 7.8 9.9 8.8 15.3 6.8 5.7 11.0 9.4 10.1 4.2 11.8 6.5 8.6 9.9 9.6 6.7 7.3 5.5 12.5 7.3 9.4 6.0 13.5 8.8 21.1 6.7 21.6 9.1 7.6 14.4 8.7 7.2 15.0 14.4 25.3 18.3 14.2 16.1 15.2 20.3 12.5 16.5 18.4 19.8 15.2 17.0 24.0 3.9 21.0 16.0 13.3 19.2 14.2 21.9 37.9 15.9 29.3 26.5 9.0 13.0 38.6 22.1 16.6 13.1 22.6 29.9 18.8 18.8 21.0 17.9 32.7 15.7 9.7 27.9 11.0 28.4 12.3 7.9 25.7 47.5 11.4 8.8 32.6 7.0 20.5 24.5 11.0 13.0 25.0 11.9 24.0 26.0 12.0 17.0 13.6 21.1 11.5 13.6 53.7 15.5 16.5 18.0 64.5 21.8 44.4 31.4 25.0 32.3 27.1 24.6 25.9 22.8 32.0 26.3 22.8 63.0 35.8 28.9 32.0 20.9 22.5 5.8 8.3 11.6 8.5 6.2 6.5 6.8 5.7 6.5 6.0 6.7 15.0 53.1 64.1 61.6 61.7 80.6 33.0 22.2 30.1 48.9 69.0 35.3 27.9 38.2 31.5 39.0 35.0 116.7 48.8 103.3 51.3 3.9 37.4 96.8 60.2 72.8 51.6 69.7 51.3 71.7 31.6 34.7 47.2 39.8 99.8 54.4 106.9 42.8 30.9 30.2 87.5 59.1 40.0 40.7 52.5 37.5 32.5 48.4 63.9 26.6 57.1 82.9 48.3 105.0 68.3 85.9 38.7 37.0 55.7 73.1 32.4 33.6 11.8 40.2 71.9 59.2 64.0 59.9 137.1 104.8 50.1 47.6 71.1 80.1 67.5 40.1 42.0 KDM5C "DXS1272E, JARID1C, MRX13, SMCX, XE169" ENSG00000126012 "Lysine demethylase 5C" P41229 X 53191321-53225422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038244, HPA046147" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA038244: AB_2675911, HPA046147: AB_2679555" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (1.56e-2)" "unprognostic (7.10e-2)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.08e-2)" "unprognostic (2.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.45e-2)" "unprognostic (1.58e-2)" "unprognostic (5.05e-3)" "unprognostic (1.96e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" 22.3 29.0 19.2 28.2 19.7 34.8 22.7 23.0 21.7 35.5 22.2 25.5 26.0 35.5 14.8 35.2 33.2 17.1 22.7 19.6 20.1 21.1 24.1 27.2 33.4 19.8 19.0 39.9 26.4 33.8 31.4 23.8 19.0 23.8 15.4 24.6 29.4 18.5 51.0 34.2 28.2 26.9 16.8 30.9 25.8 13.5 20.9 44.2 27.6 25.5 26.5 25.9 35.4 20.8 45.3 60.4 63.6 49.0 43.2 39.1 45.2 27.7 32.2 36.8 34.0 41.3 28.9 41.8 35.0 36.7 103.2 39.5 72.6 59.1 27.8 31.6 107.9 40.6 66.7 29.6 52.9 48.5 77.6 31.0 42.8 72.0 87.7 52.3 55.2 34.2 80.8 27.2 27.3 57.9 35.9 55.4 54.1 23.3 56.3 40.1 37.8 45.9 23.5 42.6 47.6 61.4 84.0 76.8 32.2 58.4 53.9 42.3 37.8 40.6 35.0 36.9 27.2 39.0 34.2 31.5 52.6 56.9 30.8 0.9 1.2 0.8 1.6 1.1 1.4 1.2 1.0 1.6 0.9 0.8 1.2 0.8 1.4 0.8 1.2 1.3 1.3 1.2 19.2 19.7 23.0 21.7 19.6 20.1 19.8 19.0 19.0 16.8 20.9 20.8 17.6 12.8 14.9 33.0 17.8 12.1 10.5 12.1 14.8 24.7 19.7 15.0 10.0 11.5 15.2 7.3 25.0 13.1 21.2 32.2 3.9 15.0 0.8 28.2 25.2 17.7 31.2 17.2 36.1 21.9 15.1 14.2 21.4 35.7 13.3 25.5 15.0 25.5 14.4 25.2 37.0 25.8 16.2 18.2 8.8 2.6 14.6 17.1 14.2 27.2 14.9 9.8 16.5 31.2 49.2 26.4 26.3 15.8 17.0 17.9 22.1 5.8 16.4 16.9 0.0 17.2 16.8 10.3 15.8 16.2 15.9 20.8 18.0 22.6 18.9 21.6 KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 116.2;Oligodendrocyte precursor cells: 118.1;Oligodendrocytes: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" 9.6 8.0 6.7 4.5 7.6 19.4 10.6 7.2 10.6 15.7 6.5 9.1 6.2 14.0 5.1 11.1 14.0 3.4 6.6 6.8 6.9 6.8 10.4 10.8 8.0 7.3 6.8 17.2 10.8 6.4 8.6 3.9 7.3 7.7 4.1 3.8 10.5 3.1 10.4 18.4 13.0 4.1 7.1 14.1 12.5 12.2 7.0 12.9 9.4 6.1 5.3 9.8 15.2 9.9 7.3 5.8 7.0 9.3 5.0 6.8 15.7 4.9 4.2 4.0 4.1 10.4 5.2 4.6 3.2 3.5 10.1 13.9 6.5 5.4 3.9 7.6 10.8 2.4 4.5 5.2 3.7 2.6 13.2 2.6 6.4 8.2 6.6 5.1 4.2 5.3 6.4 10.1 2.4 6.0 6.9 13.6 6.8 4.2 7.4 6.4 7.1 1.4 3.8 9.2 6.2 4.4 18.2 6.8 10.7 14.1 8.5 0.0 3.0 5.4 5.2 5.2 3.6 5.5 8.8 5.6 4.0 3.3 3.3 7.3 1.7 1.5 1.9 3.5 2.1 1.9 2.5 2.8 3.1 1.2 2.5 2.4 2.8 2.8 3.0 1.7 2.2 2.0 6.7 7.6 7.2 10.6 6.8 6.9 7.3 6.8 7.3 7.1 7.0 9.9 23.2 6.4 10.6 92.1 26.0 26.1 14.3 9.4 38.1 7.7 16.8 12.1 12.8 12.8 10.9 7.3 14.6 4.5 26.1 24.6 0.0 8.4 1.5 26.4 25.5 13.1 13.1 16.8 88.3 7.5 7.9 14.2 23.0 39.7 2.5 27.3 6.4 17.6 7.0 25.2 74.0 14.0 6.1 9.1 13.8 2.0 6.5 19.9 10.6 116.2 12.6 6.8 6.2 118.1 264.6 9.1 17.4 7.2 31.4 14.2 22.6 3.7 8.9 9.7 6.6 20.9 17.0 14.1 12.5 29.3 26.3 10.9 27.4 10.6 13.1 17.1 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367228 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 90.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB003673: AB_425440, HPA044884: AB_2679131" "unprognostic (4.44e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-2)" "unprognostic (4.56e-2)" "unprognostic (5.88e-3)" "unprognostic (7.50e-3)" "unprognostic (1.80e-2)" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-2)" "unprognostic (6.81e-2)" "prognostic favorable (9.53e-6)" "unprognostic (3.32e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-3)" 32.3 22.4 12.8 8.1 19.9 4.8 25.4 19.5 16.7 26.9 12.3 24.6 7.0 22.7 20.8 22.4 18.9 12.6 20.7 12.7 16.4 20.1 36.7 21.5 7.0 20.6 17.7 21.3 15.7 13.1 12.1 8.5 20.0 16.3 7.4 7.0 22.8 11.6 16.7 44.5 15.1 13.3 17.6 8.4 16.4 6.1 16.6 7.1 17.2 8.9 6.8 23.9 23.4 22.4 14.9 6.5 6.7 7.5 52.6 39.0 13.0 48.8 29.7 10.5 13.9 2.7 10.0 15.1 20.3 19.1 17.4 64.6 8.7 27.3 12.8 28.6 14.5 11.6 8.7 3.4 40.1 22.0 7.8 37.4 50.7 16.8 47.9 19.3 10.5 9.9 9.5 21.0 28.1 6.2 23.6 9.7 8.0 3.7 23.5 15.5 19.7 21.9 29.0 9.6 8.5 16.4 23.4 11.3 21.9 8.8 6.1 12.1 24.9 44.0 10.6 14.8 21.3 90.4 44.9 8.7 33.2 13.0 13.4 0.1 5.2 0.5 6.5 8.1 26.6 5.7 13.6 10.2 8.0 4.7 9.3 6.1 1.3 14.2 3.9 3.8 19.1 5.3 12.8 19.9 19.5 16.7 12.7 16.4 20.6 17.7 20.0 17.6 16.6 22.4 53.1 35.3 49.1 21.9 30.1 158.6 131.7 47.0 122.3 37.4 63.4 63.6 27.7 62.9 43.5 38.6 27.1 58.8 15.6 34.6 15.6 50.7 1.0 43.9 53.0 48.1 20.4 17.4 19.1 36.7 70.4 82.0 26.5 64.9 26.0 52.3 51.8 88.3 36.4 40.4 24.2 31.8 42.7 32.2 47.7 6.5 71.1 39.9 56.9 14.0 31.5 56.5 13.4 21.6 57.0 47.4 44.6 70.7 24.5 104.3 43.4 39.6 41.2 41.1 32.9 73.7 48.4 1.3 5.2 89.7 143.1 91.4 37.7 51.1 40.3 94.7 KEAP1 "INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454" ENSG00000079999 "Kelch like ECH associated protein 1" Q14145 19 10486125-10503558 "Cancer-related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 178.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005558, CAB025337" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centriolar satellite" Cytosol "CAB025337: , HPA005558: AB_1079175" "unprognostic (1.98e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-2)" "unprognostic (2.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (5.22e-3)" "unprognostic (2.04e-1)" "unprognostic (9.99e-2)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (5.06e-1)" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" 31.3 41.2 54.8 20.5 61.6 20.4 30.3 61.8 60.9 32.7 49.7 37.6 26.5 31.3 22.2 55.4 28.9 24.3 60.7 53.2 59.4 32.5 60.9 25.3 23.2 61.4 60.5 25.3 32.8 24.3 30.0 17.0 60.3 36.8 16.5 16.4 34.7 24.9 178.2 38.7 27.5 18.7 58.8 32.2 33.2 20.5 59.6 23.0 35.6 75.7 18.5 41.4 36.3 68.4 58.0 102.8 27.2 35.1 55.8 45.4 30.3 48.1 35.9 46.6 41.6 73.7 54.2 82.9 122.9 53.3 34.8 49.7 55.6 36.9 23.7 78.3 61.7 126.3 29.9 87.9 54.5 65.4 63.9 50.0 51.0 53.5 25.1 39.1 46.3 23.7 79.1 135.4 41.6 79.9 46.1 177.8 80.8 54.2 88.6 84.6 34.8 95.1 30.4 67.4 75.3 40.4 66.8 42.4 42.1 23.9 37.8 82.3 56.5 72.9 41.0 86.0 57.0 86.8 113.0 81.1 58.0 78.5 56.0 36.4 37.9 41.4 55.3 33.8 53.1 26.3 38.5 52.0 45.4 11.7 23.6 33.7 20.9 42.5 34.6 31.4 50.2 41.8 54.8 61.6 61.8 60.9 53.2 59.4 61.4 60.5 60.3 58.8 59.6 68.4 18.3 28.9 20.8 5.5 13.8 21.9 24.4 40.3 27.9 21.5 15.7 11.4 24.0 21.5 25.4 11.0 8.4 27.3 11.6 33.2 13.7 32.8 27.5 13.4 17.1 27.8 26.9 45.2 5.3 36.3 25.2 23.5 18.8 13.3 12.0 22.8 35.3 34.4 29.0 26.9 5.9 21.4 40.7 15.1 13.4 43.9 29.2 16.1 10.6 3.7 41.8 43.0 7.2 11.6 18.3 29.8 27.1 25.9 26.6 33.3 36.8 24.9 17.2 13.9 13.1 17.7 22.4 21.2 16.6 34.7 22.0 26.8 20.1 29.6 31.5 24.8 KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 56.3;testis: 32.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 79.7;Oligodendrocytes: 30.1;Squamous epithelial cells: 16.8" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HEL: 31.7;K-562: 26.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (5.78e-3)" "unprognostic (1.08e-5)" "unprognostic (5.29e-3)" "unprognostic (4.85e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" "unprognostic (2.29e-3)" "unprognostic (9.24e-2)" "unprognostic (7.05e-2)" "unprognostic (3.32e-2)" "unprognostic (3.25e-3)" 0.2 0.0 1.8 0.8 2.7 56.3 0.3 1.7 2.2 0.9 1.4 0.1 0.0 0.2 0.0 0.8 0.5 0.0 0.3 2.0 1.5 0.6 0.3 0.5 10.6 2.5 2.2 0.2 0.2 0.0 0.2 0.4 2.4 0.3 0.0 0.1 0.6 0.1 0.2 0.1 0.9 0.0 1.9 4.9 0.2 32.3 2.4 1.3 0.3 0.0 6.7 0.1 0.4 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 31.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.5 0.1 0.6 0.0 0.0 0.1 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 1.7 2.2 2.0 1.5 2.5 2.2 2.4 1.9 2.4 2.8 0.2 0.0 0.0 0.3 0.0 0.0 1.3 0.2 4.0 0.0 0.3 0.1 0.4 0.0 1.4 3.7 0.0 0.1 0.1 0.0 1.9 0.3 2.4 0.2 0.1 0.1 0.0 79.7 3.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 3.1 0.0 1.4 0.2 16.8 0.0 0.1 0.0 0.0 0.0 0.9 KIAA1109 "FLJ21404, FSA, KIAA1371, Tweek" ENSG00000138688 KIAA1109 Q2LD37 4 122152331-122362758 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 245.2;Inhibitory neurons: 246.5;Oligodendrocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038076 Approved Approved Nucleoplasm,Centrosome NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Centrosome" "HPA038076: AB_10670652" "unprognostic (2.53e-1)" "unprognostic (2.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (1.04e-1)" "unprognostic (6.62e-2)" "unprognostic (7.61e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.33e-8)" "unprognostic (2.04e-1)" "unprognostic (3.55e-1)" "unprognostic (2.28e-2)" "unprognostic (2.29e-2)" 29.3 24.9 39.5 13.7 48.4 60.3 31.7 41.7 42.8 29.8 62.3 29.6 18.8 27.6 29.8 17.5 27.2 19.8 22.9 36.0 38.5 27.8 21.3 28.2 19.8 48.4 39.1 41.6 24.8 56.3 47.1 17.5 44.6 21.9 22.1 82.4 22.4 21.7 55.5 28.7 28.3 22.1 35.4 26.4 23.3 26.6 44.0 23.1 31.5 42.2 16.8 24.5 25.6 60.5 30.5 9.5 22.3 14.8 36.3 46.7 11.6 13.5 25.3 13.6 14.9 7.2 15.7 15.9 7.6 32.2 18.4 11.2 13.7 16.7 22.0 12.1 8.8 17.7 18.4 13.7 18.9 16.7 9.4 27.2 19.6 16.4 22.3 37.2 29.3 17.0 11.6 18.8 28.5 10.3 14.5 13.0 7.4 14.6 10.7 8.2 30.8 4.1 24.1 22.6 13.0 11.6 8.4 9.7 18.8 35.8 10.6 13.5 39.8 16.8 16.7 14.0 14.0 18.1 12.5 11.5 17.8 14.4 12.6 1.8 0.7 4.3 1.6 1.8 1.7 1.2 1.1 1.1 0.7 1.8 0.9 1.1 3.3 1.0 0.9 1.1 1.6 0.4 39.5 48.4 41.7 42.8 36.0 38.5 48.4 39.1 44.6 35.4 44.0 60.5 94.6 86.6 42.8 245.2 36.0 20.9 22.0 19.8 26.2 126.0 36.2 27.6 69.2 22.8 35.9 42.3 125.1 12.0 59.6 42.4 1.9 13.8 35.1 34.3 52.8 47.2 21.6 27.1 194.0 17.5 7.0 41.2 59.7 47.2 21.5 64.4 35.0 24.1 12.7 92.5 246.5 27.3 20.3 30.1 17.5 27.7 51.3 41.0 16.0 153.6 32.5 60.9 26.8 161.9 239.9 20.7 34.9 50.8 47.9 19.3 50.0 10.3 33.1 145.0 32.9 63.1 54.9 63.2 33.9 28.9 24.4 13.0 52.0 34.0 32.0 23.0 KIF2A "HK2, KIF2" ENSG00000068796 "Kinesin family member 2A" O00139 5 62306162-62391025 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Motor protein" "Cancer-related genes, Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004715, HPA004716" Approved Enhanced Nucleoplasm,Nucleoli,Centrosome Yes No 300000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Nucleoli, Centrosome" "HPA004715: AB_2667215, HPA004716: AB_1079211" "unprognostic (2.40e-2)" "unprognostic (3.43e-1)" "prognostic favorable (1.70e-4)" "unprognostic (2.74e-2)" "unprognostic (1.43e-1)" "prognostic favorable (5.45e-4)" "prognostic unfavorable (3.17e-6)" "unprognostic (8.77e-3)" "unprognostic (4.69e-2)" "unprognostic (9.10e-2)" "unprognostic (1.85e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (3.53e-2)" "unprognostic (2.95e-2)" "unprognostic (1.65e-1)" "unprognostic (1.58e-1)" 11.9 7.7 15.6 23.2 20.7 12.8 10.8 15.5 17.7 19.5 0.0 13.8 11.5 12.0 6.3 12.5 17.6 12.9 6.2 17.4 23.0 8.0 5.3 9.8 32.8 17.9 17.5 12.9 10.2 12.3 8.5 16.9 18.4 9.9 14.7 42.7 6.9 11.4 4.8 5.9 15.9 13.1 14.6 18.4 9.6 49.1 16.1 43.6 12.6 6.8 28.9 20.2 7.2 28.0 47.3 46.9 81.4 67.3 28.8 39.6 65.2 51.2 38.5 54.6 67.5 53.1 49.6 111.9 53.3 41.9 67.2 29.1 61.3 37.7 72.5 116.8 44.2 113.8 41.2 27.8 34.7 65.3 42.9 30.5 26.6 50.1 47.5 33.1 49.1 66.5 86.6 66.7 46.9 36.1 104.4 33.1 42.6 12.0 31.9 78.3 59.6 65.3 25.4 55.4 68.0 55.9 67.0 27.9 34.7 55.3 37.6 38.5 39.8 31.9 52.2 40.5 51.3 64.8 94.9 114.1 36.4 74.5 39.8 10.4 4.6 4.7 29.2 5.0 35.3 13.5 29.8 32.7 6.2 10.5 26.3 29.0 7.8 23.2 3.3 9.6 42.3 17.7 15.6 20.7 15.5 17.7 17.4 23.0 17.9 17.5 18.4 14.6 16.1 28.0 30.8 16.0 14.1 54.5 44.1 16.8 41.4 20.1 39.3 45.5 17.9 23.9 9.4 4.3 20.5 20.2 104.3 20.3 73.4 23.1 13.7 37.5 113.8 103.3 47.2 21.4 21.0 42.3 56.7 30.9 22.6 28.2 20.4 43.4 17.7 25.6 19.6 4.4 15.4 52.2 64.5 7.9 14.2 12.9 22.1 130.7 13.1 83.6 12.4 26.2 104.9 28.0 76.2 119.6 156.0 26.6 26.1 13.2 47.8 42.7 13.5 18.7 49.2 92.9 26.3 33.1 25.4 118.9 42.8 34.3 9.5 43.9 77.9 48.9 11.0 56.1 KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 33.0;lymphoid tissue: 37.4;testis: 76.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1860.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "white matter: 2.1" "Not detected" "Not detected" "HPA006219, HPA079172" Enhanced Supported Nucleoplasm,Midbody,Centrosome Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" Midbody "HPA006219: AB_2667540, HPA079172: " "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.07e-7)" "unprognostic (7.49e-3)" "unprognostic (3.33e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (4.27e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.33e-3)" "unprognostic (1.49e-1)" "unprognostic (1.86e-2)" "unprognostic (2.41e-1)" 0.7 0.8 0.7 7.0 0.7 33.0 1.6 2.3 0.7 1.8 1.1 6.2 5.5 1.8 0.7 7.3 0.9 1.3 1.3 0.6 1.1 0.8 0.7 1.3 16.4 1.1 0.9 0.6 0.5 1.3 0.4 5.4 1.4 0.8 7.6 0.8 1.3 0.7 0.9 6.0 5.1 3.2 0.9 3.7 3.5 76.5 0.8 37.4 1.1 0.7 19.2 2.1 2.7 0.8 119.7 45.8 99.6 79.8 5.3 11.6 66.6 86.9 62.1 175.0 151.3 77.6 84.2 136.2 41.3 43.2 121.7 55.2 102.8 59.6 158.2 89.1 44.4 162.1 83.3 65.5 0.6 121.5 71.8 2.7 5.8 125.0 60.3 16.5 57.6 95.4 130.4 113.1 112.4 46.5 127.5 72.9 97.1 58.4 56.5 101.1 149.3 86.4 29.6 42.8 68.3 48.5 116.1 81.6 71.5 71.9 47.2 90.7 34.7 62.9 124.2 69.0 155.6 59.4 65.0 195.3 40.3 115.4 123.9 0.0 0.0 0.0 0.9 0.0 0.0 0.6 1.7 1.2 0.1 0.1 0.3 0.2 0.0 2.0 0.1 0.8 2.9 0.5 0.7 0.7 2.3 0.7 0.6 1.1 1.1 0.9 1.4 0.9 0.8 0.8 0.1 0.0 0.5 1.6 1.3 1.8 0.5 2.4 0.0 1.0 0.9 0.9 1.6 0.0 1.7 1.8 2.1 12.2 1.9 2.9 1.9 0.3 461.1 1.2 1.4 1.6 0.0 34.5 0.8 0.4 23.4 3.2 3.1 2.1 0.0 13.0 2.9 0.2 9.2 0.0 1.0 3.5 0.0 1.9 1.5 1860.6 9.3 3.4 0.0 1.0 4.3 0.4 0.0 0.5 0.2 0.1 0.2 6.8 7.8 0.8 0.3 0.2 0.3 0.2 6.6 0.8 3.4 60.6 36.8 4.6 0.4 3.7 2.7 0.8 7.4 0.7 KIF5B "KNS, KNS1" ENSG00000170759 "Kinesin family member 5B" P33176 10 32009015-32056425 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009846, HPA037589, HPA037590" Approved Enhanced "Centriolar satellite,Cytosol" NA Yes 97000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" "Centriolar satellite, Cytosol" "CAB009846: AB_2280915, HPA037589: AB_2675563, HPA037590: AB_2675564" "unprognostic (4.94e-3)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (4.00e-2)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (6.37e-3)" "unprognostic (2.03e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.43e-2)" "unprognostic (2.39e-1)" "unprognostic (8.06e-2)" "unprognostic (1.76e-1)" 59.7 41.8 110.0 46.7 128.2 84.9 45.3 107.7 149.7 47.3 75.6 66.4 52.0 54.1 30.3 52.7 39.2 59.8 87.4 85.8 100.2 44.7 31.9 52.5 39.9 121.9 123.8 27.6 41.8 91.6 22.9 54.4 120.6 65.9 63.6 45.1 39.1 52.0 65.0 38.9 54.7 81.3 128.1 48.1 51.4 64.4 116.8 44.0 50.5 67.3 36.6 60.8 29.8 143.4 115.8 96.4 127.3 89.9 89.2 97.7 54.4 155.6 73.3 117.6 99.6 106.6 124.0 78.7 65.8 185.8 66.9 93.3 117.6 99.4 156.4 68.4 64.1 100.2 87.9 104.5 102.5 70.5 105.6 79.9 138.0 135.8 94.0 93.4 152.8 68.2 122.9 80.5 164.7 69.7 74.0 39.7 20.7 110.1 43.4 95.7 237.2 32.6 90.6 79.5 123.3 89.9 120.4 47.5 117.3 88.0 57.5 99.4 128.4 118.7 111.0 139.3 117.2 24.2 29.8 90.9 113.2 142.2 114.1 41.8 25.9 44.0 19.1 33.0 18.7 23.7 24.0 20.6 24.7 24.3 21.1 20.8 51.1 24.3 35.7 47.9 29.4 18.4 110.0 128.2 107.7 149.7 85.8 100.2 121.9 123.8 120.6 128.1 116.8 143.4 160.3 182.7 206.8 49.3 86.3 213.1 177.7 200.6 66.0 181.9 119.0 103.8 396.0 115.8 198.4 104.8 100.1 121.0 125.5 145.0 45.0 209.4 185.5 167.8 171.4 181.0 132.3 69.2 44.6 176.0 134.9 141.2 85.6 158.9 91.2 159.7 88.5 46.2 132.7 151.4 56.0 227.3 213.6 111.8 129.1 51.8 59.0 137.2 101.4 84.3 169.3 160.5 82.4 61.9 83.3 202.2 164.9 130.9 84.2 254.1 120.2 59.5 206.1 123.8 85.5 176.0 244.8 566.0 195.6 87.6 236.7 331.9 116.0 137.4 208.1 246.8 KIFC3 ENSG00000140859 "Kinesin family member C3" Q9BVG8 16 57758217-57863053 "Cancer-related genes, Predicted intracellular proteins" "Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 169.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 141.8;Early spermatids: 203.7;Late spermatids: 430.5;Rod photoreceptor cells: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "A549: 215.1;HMC-1: 204.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021240 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA021240: AB_1852509" "unprognostic (1.53e-1)" "unprognostic (3.10e-3)" "unprognostic (8.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.95e-3)" "unprognostic (2.29e-1)" "unprognostic (3.71e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (7.66e-3)" "unprognostic (1.59e-2)" "unprognostic (2.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.14e-1)" "unprognostic (1.01e-2)" "unprognostic (1.40e-1)" "unprognostic (4.33e-2)" 30.5 29.0 25.4 25.9 16.6 14.5 23.8 28.2 35.9 22.7 13.4 21.0 30.7 22.2 30.1 26.2 14.8 21.1 62.7 21.2 38.5 169.2 85.6 45.4 13.5 25.7 14.2 19.0 76.6 26.1 30.9 25.6 29.9 26.3 13.4 82.3 22.1 22.3 13.7 80.0 37.4 13.0 7.3 21.2 24.5 64.9 35.0 4.1 68.1 6.6 9.6 30.3 24.4 46.4 41.5 215.1 15.2 32.8 4.9 10.4 26.8 51.1 65.1 76.4 36.3 58.2 62.6 4.4 64.5 32.8 79.3 43.2 1.8 47.1 25.6 2.1 10.2 34.6 72.9 75.8 28.8 5.0 204.7 14.2 16.6 40.3 40.5 39.1 18.4 11.9 61.7 7.4 28.6 28.2 7.4 60.9 10.3 16.2 45.6 4.6 23.1 33.0 48.9 21.3 5.3 10.7 86.8 60.7 55.8 10.5 18.2 26.0 39.9 98.4 69.3 45.3 71.5 5.9 3.7 4.3 49.9 3.3 94.7 0.1 0.2 0.2 1.5 0.0 0.1 0.7 0.6 1.5 0.1 0.5 0.3 0.4 0.5 0.1 0.7 0.1 0.0 0.6 25.4 16.6 28.2 35.9 21.2 38.5 25.7 14.2 29.9 7.3 35.0 46.4 40.0 48.1 33.3 28.4 0.5 12.6 12.3 8.1 5.7 5.7 5.0 7.4 8.4 38.6 15.3 66.2 141.8 31.8 9.2 0.1 50.9 50.6 203.7 18.5 4.8 25.3 0.0 4.8 15.8 63.6 6.4 11.8 2.0 15.6 3.8 0.9 25.4 16.6 25.7 1.7 14.8 2.1 2.0 6.6 10.2 430.5 12.2 24.7 28.4 16.9 1.1 10.6 15.5 27.2 28.9 67.1 1.2 22.6 0.8 13.8 34.7 51.4 14.9 165.5 19.7 10.3 16.5 7.7 9.9 1.0 8.2 19.4 5.8 10.5 0.9 7.9 KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "placenta: 233.1" "Cell type enriched" "Detected in many" 26 "Syncytiotrophoblasts: 1336.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.2" "Region enriched" "Detected in some" 6 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "BJ: 145.5;U-2 OS: 59.4" "Not detected" "Not detected" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" NA NA 860000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB017775: , HPA035542: AB_2674677" "unprognostic (9.64e-2)" "unprognostic (1.78e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.63e-1)" "unprognostic (8.98e-12)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "prognostic favorable (6.29e-6)" 0.0 0.0 0.4 0.0 0.8 0.0 0.1 0.6 0.6 0.3 0.8 0.2 0.9 0.2 0.0 0.1 0.1 0.0 0.1 0.4 10.7 2.4 4.3 1.3 0.0 1.8 0.3 0.0 1.0 0.0 3.1 233.1 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.1 1.3 0.2 0.2 2.0 3.2 5.2 1.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.4 145.5 1.8 2.5 0.7 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.2 0.0 0.2 0.1 0.0 0.0 0.9 0.2 0.1 0.0 0.7 0.0 0.8 0.2 0.3 0.0 0.1 59.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.6 0.6 0.4 10.7 1.8 0.3 0.4 0.2 1.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 4.0 7.5 0.0 1.0 1.2 0.6 0.0 1.5 2.2 0.0 0.0 9.3 0.0 1.5 0.0 11.3 40.2 0.2 0.0 1.4 0.0 0.0 0.1 4.9 6.9 1.9 4.1 0.5 0.0 0.4 0.7 2.8 15.1 0.0 0.0 0.6 0.0 0.0 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.5 0.0 0.1 50.1 17.0 1.4 0.4 0.0 0.0 0.0 7.1 0.6 1.1 0.0 0.0 1336.6 0.1 0.1 2.1 14.3 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Group enriched" "Detected in many" 13 "HEL: 247.2;HMC-1: 496.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 6.6 1.8 8.2 5.3 6.3 6.4 114.9 21.4 6.5 17.6 5.1 13.5 9.2 9.6 5.9 13.0 2.9 20.3 3.4 23.9 5.1 12.4 0.8 21.8 3.4 6.8 12.3 45.0 2.6 1.7 1.9 10.0 8.8 5.6 16.0 3.2 21.4 8.7 1.1 24.5 13.4 10.1 5.9 5.0 17.4 6.2 16.7 3.1 47.1 6.9 6.2 14.5 4.9 5.1 0.0 0.0 3.9 0.0 0.7 0.3 0.0 3.3 4.6 12.6 15.8 0.0 0.0 0.0 0.0 7.3 0.6 0.3 2.6 0.0 10.8 0.0 5.9 247.2 0.0 0.0 0.0 0.0 496.2 0.0 0.0 0.0 0.0 0.0 28.4 4.3 3.5 0.5 0.0 0.0 1.4 2.5 6.9 0.0 0.0 0.8 0.0 0.0 0.0 24.2 6.0 2.1 0.0 0.0 0.0 14.1 0.0 2.6 0.3 0.5 0.0 4.9 0.1 0.4 0.0 0.0 0.5 0.9 0.6 20.3 0.0 12.8 0.1 0.0 2.3 0.0 0.4 0.9 2.3 0.0 0.0 0.0 1.0 13.1 1.4 0.1 0.0 0.2 8.2 6.3 21.4 6.5 23.9 5.1 6.8 12.3 8.8 5.9 16.7 5.1 7.3 6.4 21.9 9.8 1.0 14.3 0.9 0.4 2.2 4.5 83.1 59.2 0.7 4.3 3.6 3.7 0.0 0.1 5.2 0.4 3.9 1.0 0.0 0.2 0.7 9.2 5.4 15.5 0.9 0.0 0.1 2.8 8.6 0.7 529.3 0.5 1.8 0.0 0.3 0.0 111.2 0.5 101.7 0.3 4.2 0.4 1.2 1.6 211.7 14.0 0.2 2.4 0.0 16.1 3.7 0.0 0.1 0.0 3.2 0.5 0.0 0.8 0.1 0.2 0.0 0.7 0.8 0.1 12.3 2.2 3.8 0.3 8.8 63.7 0.6 0.3 KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Collecting duct cells: 69.9;Excitatory neurons: 46.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 299.8;SK-BR-3: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" NA NA 260000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" 13.2 3.9 2.3 8.2 3.5 0.3 10.6 0.2 3.1 12.9 1.2 18.7 9.6 15.1 2.8 14.3 4.0 18.5 7.0 2.9 0.3 16.0 2.3 31.6 3.3 0.0 2.5 6.0 3.7 3.7 0.2 15.0 0.0 15.1 22.6 2.3 8.8 14.8 3.1 7.1 11.6 18.8 0.3 3.5 17.4 6.3 5.2 5.1 5.9 14.4 10.4 12.3 1.3 6.2 14.3 7.1 7.1 0.9 29.0 61.5 0.0 77.6 60.1 13.5 6.4 299.8 11.0 0.0 2.2 73.3 14.9 49.5 11.5 20.1 14.2 0.1 9.5 0.0 9.5 2.6 4.4 1.9 0.0 53.5 20.6 41.6 26.8 6.3 17.9 0.0 0.0 0.3 6.8 2.5 0.2 0.0 4.8 17.7 17.9 0.0 12.6 0.0 25.0 6.5 2.3 4.8 18.5 118.9 2.2 6.5 57.2 4.3 10.0 60.7 7.4 69.0 6.8 0.0 0.0 0.0 8.4 0.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.5 0.2 3.1 2.9 0.3 0.0 2.5 0.0 0.3 5.2 6.2 42.5 19.2 38.3 9.4 0.5 13.5 11.2 7.5 83.6 2.7 12.2 8.1 4.4 1.5 16.5 69.9 0.0 0.1 0.0 12.0 1.9 4.4 0.4 3.1 6.8 43.1 9.5 0.0 46.5 18.2 0.1 34.5 43.3 3.4 0.0 2.1 5.0 0.4 1.2 21.9 61.4 8.5 18.3 3.2 5.7 0.9 14.0 1.9 12.4 18.7 0.0 0.3 0.0 3.0 0.6 8.7 3.0 3.8 1.4 11.2 2.3 1.4 9.8 1.2 13.1 2.2 27.2 0.2 0.5 18.5 5.3 0.0 1.0 4.4 14.7 3.2 KLF4 "EZF, GKLF" ENSG00000136826 "Kruppel like factor 4" O43474 9 107484852-107490482 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 254.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1054.7;Basal squamous epithelial cells: 832.1;Distal enterocytes: 789.2;Intestinal goblet cells: 710.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.0;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.2;hTCEpi: 84.4;hTERT-HME1: 54.5;OE19: 47.2;U-2197: 111.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002926 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA002926: AB_1852541" "unprognostic (2.06e-1)" "unprognostic (1.42e-2)" "unprognostic (1.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-3)" "unprognostic (3.44e-2)" "unprognostic (6.49e-2)" "unprognostic (3.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.18e-2)" "unprognostic (1.08e-1)" "prognostic favorable (3.93e-5)" "unprognostic (2.55e-1)" "unprognostic (1.67e-1)" "unprognostic (8.13e-2)" "unprognostic (8.32e-2)" 73.5 23.9 5.1 21.0 4.7 50.5 63.7 4.0 7.8 53.2 4.6 87.3 28.4 16.0 5.6 102.1 43.0 44.3 31.0 3.7 5.1 6.2 12.4 44.8 5.6 5.0 4.7 29.0 7.0 5.7 4.9 32.4 5.0 16.7 96.0 0.8 27.5 7.6 14.2 254.7 40.5 40.6 4.1 24.1 58.0 17.8 6.0 17.0 25.2 23.2 14.5 43.9 58.9 4.0 13.3 3.9 0.6 0.1 16.6 39.2 5.2 4.4 27.6 6.7 8.1 1.0 18.0 0.0 0.6 6.9 23.7 8.7 6.1 3.9 3.0 0.0 2.2 0.0 7.5 0.3 21.6 0.0 0.0 5.0 84.4 14.0 54.5 1.5 0.6 0.2 0.6 0.0 4.1 7.3 0.0 1.4 4.1 47.2 25.2 0.3 1.6 0.2 2.3 3.7 0.4 0.2 4.0 11.8 15.2 12.7 1.3 5.4 3.5 3.6 0.1 111.5 2.1 0.2 0.1 0.0 3.4 2.6 6.8 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 1.0 0.2 0.0 0.1 5.1 4.7 4.0 7.8 3.7 5.1 5.0 4.7 5.0 4.1 6.0 4.0 1054.7 12.8 41.1 0.3 32.2 436.0 284.3 143.0 832.1 0.5 206.7 205.0 70.3 35.8 71.5 1.8 8.4 49.1 15.0 789.2 1.9 24.4 263.1 154.1 216.0 336.6 123.8 4.8 0.0 38.7 75.5 463.2 537.2 297.4 54.7 4.7 216.0 4.6 89.9 0.0 0.2 710.9 83.4 232.9 282.0 163.0 143.8 401.0 206.3 16.9 36.8 2.0 0.0 0.0 0.0 49.3 540.9 60.5 38.3 187.3 198.0 2.1 46.4 2.0 39.5 463.7 130.0 21.6 15.9 639.9 674.0 107.9 26.8 63.5 332.6 236.8 KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1105.5;Basal squamous epithelial cells: 757.5;Glandular and luminal cells: 678.2;Squamous epithelial cells: 1028.4;Suprabasal keratinocytes: 685.9;Urothelial cells: 1495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 111.8;HaCaT: 128.8;HBEC3-KT: 112.2;hTCEpi: 156.1;OE19: 246.3;RT4: 136.3;SiHa: 114.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" 6.5 5.9 4.2 18.0 9.1 63.5 36.2 0.6 3.3 49.9 2.7 161.2 130.4 6.7 6.6 242.0 37.5 55.9 3.3 2.6 3.4 8.5 4.7 29.6 2.0 0.8 3.4 4.5 11.9 0.5 10.9 18.8 0.7 23.1 145.4 0.4 79.8 14.4 19.2 234.9 146.2 6.6 0.5 1.5 82.2 12.0 4.1 12.0 25.7 7.8 53.6 111.5 122.2 1.0 22.3 31.1 0.2 0.4 1.1 1.5 34.1 12.9 29.8 5.6 6.9 28.5 111.8 0.4 68.9 11.4 2.3 128.8 39.0 112.2 8.9 0.9 11.0 0.4 61.9 2.8 7.8 10.5 1.9 8.1 156.1 1.7 61.1 5.7 0.1 3.8 1.6 2.2 25.5 7.9 2.1 0.8 1.4 246.3 43.3 2.0 28.3 2.5 87.3 136.3 2.9 1.3 114.5 18.3 8.5 13.9 2.5 2.5 0.3 7.8 23.1 0.2 5.4 3.7 1.9 3.8 10.8 2.1 9.5 24.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 4.2 9.1 0.6 3.3 2.6 3.4 0.8 3.4 0.7 0.5 4.1 1.0 7.8 163.5 123.3 0.7 5.2 518.9 1105.5 185.6 757.5 0.4 79.9 57.0 6.0 91.5 218.5 36.8 2.1 77.8 4.6 420.7 21.5 31.8 448.3 302.1 44.1 12.5 203.2 0.4 1.6 46.1 98.5 33.4 425.1 678.2 3.8 0.9 2.2 4.7 6.1 10.1 11.6 387.4 46.8 0.9 34.6 241.4 6.5 12.4 58.7 1.9 4.3 0.0 1.0 1.0 0.6 88.6 374.9 1.5 15.7 632.1 260.0 3.5 159.3 0.2 0.0 38.4 32.4 8.8 26.3 1028.4 685.9 58.0 17.4 0.5 505.4 1495.5 KLF6 "BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9" ENSG00000067082 "Kruppel like factor 6" Q99612 10 3775996-3785281 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 436.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 2075.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013529, HPA069585" Supported Supported Nucleoplasm,Nucleoli,Vesicles,Cytosol No No "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Vesicles, Cytosol" "CAB013529: AB_2533431, HPA069585: AB_2686157" "unprognostic (1.23e-1)" "unprognostic (1.53e-2)" "unprognostic (1.47e-3)" "unprognostic (4.53e-2)" "unprognostic (1.47e-1)" "unprognostic (7.55e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.83e-2)" "unprognostic (1.36e-2)" "unprognostic (2.35e-2)" "prognostic favorable (2.28e-4)" "unprognostic (8.07e-3)" "unprognostic (4.85e-2)" "unprognostic (6.87e-2)" "unprognostic (1.37e-2)" 211.3 46.9 19.0 122.1 18.0 436.6 129.7 19.2 22.4 95.4 21.9 92.1 55.4 98.1 17.7 165.5 77.2 181.9 49.7 18.0 19.2 64.1 141.8 117.0 65.4 29.4 20.1 47.3 118.3 31.8 12.0 98.2 25.2 32.8 99.6 18.4 73.8 33.7 84.9 197.1 106.0 208.2 22.7 64.3 73.2 14.6 23.0 56.8 193.9 41.3 45.0 136.3 92.7 25.0 55.0 14.7 27.2 9.0 155.1 154.3 17.1 91.7 46.5 95.9 64.8 38.0 71.4 15.6 20.8 100.0 74.5 32.7 17.0 84.9 79.5 76.6 10.2 2.2 17.5 35.8 66.4 10.3 51.5 51.4 158.2 68.6 129.3 34.2 99.3 10.1 17.5 117.9 123.6 4.0 19.4 15.9 10.2 29.2 26.0 12.6 28.2 55.5 94.1 53.4 12.0 11.5 22.5 64.0 142.8 73.5 32.0 8.6 130.9 128.7 17.8 76.9 43.0 22.6 78.1 28.6 34.7 13.7 40.8 318.8 85.2 234.1 129.8 74.2 115.9 81.1 147.4 131.5 67.6 70.9 44.9 69.0 391.6 72.5 104.6 152.8 120.6 148.7 19.0 18.0 19.2 22.4 18.0 19.2 29.4 20.1 25.2 22.7 23.0 25.0 511.0 1246.8 489.4 14.0 716.9 585.5 1298.4 625.8 1227.0 39.6 985.9 630.0 63.6 544.7 451.9 138.0 33.3 163.1 518.3 1507.0 21.5 808.6 58.0 1065.6 618.9 469.9 397.3 77.9 18.5 553.0 473.8 545.5 1120.3 1905.9 626.7 195.9 248.4 309.9 583.6 37.0 10.0 746.7 429.3 968.7 885.1 53.2 130.5 992.1 483.8 58.1 609.8 42.9 150.4 7.5 4.3 857.9 949.9 133.9 1172.5 600.2 1009.9 97.4 342.0 90.1 138.1 194.8 441.8 9.0 19.4 2075.6 628.2 195.9 920.5 67.1 542.0 572.5 KLHL8 KIAA1378 ENSG00000145332 "Kelch like family member 8" Q9P2G9 4 87160103-87240314 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 60.4" "Cell type enriched" "Detected in all" 4 "Muller glia cells: 216.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013856, HPA017762" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA013856: AB_1852594, HPA017762: AB_2669660" "unprognostic (2.93e-2)" "unprognostic (4.91e-3)" "unprognostic (3.44e-2)" "unprognostic (4.66e-2)" "unprognostic (1.18e-1)" "unprognostic (3.27e-2)" "unprognostic (2.12e-1)" "unprognostic (4.46e-3)" "unprognostic (3.27e-2)" "unprognostic (2.06e-2)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "prognostic favorable (1.53e-5)" "unprognostic (4.24e-3)" "unprognostic (3.05e-1)" "unprognostic (3.57e-3)" "unprognostic (1.57e-3)" 6.7 7.3 4.6 6.1 4.7 3.1 9.4 7.0 4.8 8.7 1.9 8.0 7.8 6.8 60.4 4.8 5.4 4.9 4.6 4.1 5.6 12.0 11.2 5.2 5.8 4.1 5.4 6.0 5.2 8.5 3.6 4.2 3.6 5.5 8.9 27.2 7.1 7.4 13.7 4.0 7.6 6.6 4.7 6.3 4.2 4.3 5.9 8.5 18.9 9.7 4.8 6.0 4.2 5.0 9.9 8.5 15.1 6.8 13.5 9.8 8.1 12.4 6.6 8.1 9.5 13.8 7.3 14.3 9.8 9.2 6.6 4.1 16.2 12.2 17.4 13.7 10.1 17.4 6.0 8.1 11.5 28.9 10.5 12.4 8.6 12.4 12.4 7.9 9.7 10.6 22.8 12.7 8.5 10.9 34.8 14.4 3.8 22.1 3.4 12.9 12.9 8.7 13.7 10.1 31.6 11.0 8.1 19.6 9.2 5.6 6.8 21.0 9.2 10.2 12.6 10.9 10.4 18.7 13.1 25.1 7.7 13.5 11.4 2.0 12.2 7.6 2.9 9.2 4.6 3.2 2.2 2.4 10.4 3.5 4.0 4.0 8.6 8.4 9.8 2.6 0.9 5.0 4.6 4.7 7.0 4.8 4.1 5.6 4.1 5.4 3.6 4.7 5.9 5.0 9.5 3.2 22.9 29.4 14.3 13.8 10.8 10.1 13.6 22.8 11.1 7.7 15.4 5.7 11.6 44.1 41.7 4.1 12.1 21.4 11.7 5.2 4.0 8.3 21.4 12.8 9.0 12.4 44.6 4.5 6.9 10.4 3.1 9.8 7.6 16.8 8.6 20.0 9.7 23.5 41.5 10.8 4.1 38.8 12.0 3.5 9.6 23.3 10.6 24.4 22.1 216.0 11.3 47.3 35.7 4.9 12.2 8.2 6.4 13.8 14.5 19.2 10.1 47.0 13.1 20.1 9.2 32.5 22.5 12.9 14.8 23.8 9.9 4.4 15.2 11.4 KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 111.8;esophagus: 412.5;vagina: 190.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Basal respiratory cells: 61.4;Club cells: 113.9;Pancreatic endocrine cells: 74.8;Prostatic glandular cells: 68.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 67.2;HaCaT: 158.7;OE19: 68.1" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" 8.6 0.6 0.7 0.2 0.4 0.6 6.2 1.2 0.4 111.8 1.0 1.5 0.3 1.7 0.2 412.5 8.6 3.5 1.3 0.3 1.4 0.6 0.3 8.7 0.0 2.6 1.7 19.7 0.6 0.2 1.5 0.2 2.8 7.2 0.6 0.3 55.2 0.5 0.2 65.7 2.6 0.6 0.7 0.2 1.8 6.0 1.0 0.3 0.6 0.1 18.8 0.6 190.6 0.4 21.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 67.2 0.0 6.6 0.0 0.1 158.7 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 68.1 0.6 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.4 1.2 0.4 0.3 1.4 2.6 1.7 2.8 0.7 1.0 0.4 0.3 32.1 2.6 0.0 0.0 7.5 15.6 61.4 9.1 1.0 12.3 14.0 0.7 8.6 113.9 0.0 0.0 0.0 0.2 1.2 0.0 7.5 0.3 2.1 1.0 1.7 0.0 0.0 0.1 15.4 0.0 6.0 1.1 8.0 0.0 0.1 1.1 0.0 0.1 0.0 0.6 0.0 22.4 0.0 0.6 0.6 11.5 0.5 0.0 0.0 0.6 0.3 0.0 0.0 0.5 74.8 0.0 6.0 0.0 68.6 0.0 0.0 15.8 0.5 0.0 0.4 2.6 1.0 1.6 28.0 4.3 0.0 0.5 0.5 0.0 29.6 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.2;skin 1: 239.8;vagina: 186.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 152.1;Club cells: 217.9;Late spermatids: 339.0;Prostatic glandular cells: 234.8;Squamous epithelial cells: 176.4;Suprabasal keratinocytes: 217.1;Urothelial cells: 186.1" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;HaCaT: 41.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" NA NA 1800000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 28.4 0.2 0.0 0.4 0.0 0.0 17.1 0.9 0.1 109.8 44.5 1.9 0.7 7.2 2.6 324.2 34.2 59.3 2.0 1.7 0.0 0.3 0.8 18.9 0.0 0.2 0.1 1.6 89.1 0.0 8.8 0.0 0.3 64.9 0.6 0.7 169.5 4.2 1.9 239.8 1.4 0.3 0.0 0.1 113.3 14.4 0.6 2.5 0.4 0.3 27.2 1.4 186.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.4 0.1 13.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.7 0.0 0.2 0.1 0.3 0.0 0.6 0.0 0.2 86.6 10.4 0.0 0.4 106.9 152.1 131.6 13.1 0.2 33.4 35.3 0.8 88.6 217.9 0.0 0.0 0.0 0.0 0.1 0.0 9.2 111.6 4.7 1.1 3.8 20.3 0.0 0.0 130.2 0.0 9.1 91.3 15.6 1.3 0.0 0.0 0.0 0.3 0.0 0.0 10.7 118.0 0.0 11.4 339.0 2.8 1.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 79.4 0.0 0.4 0.5 234.8 0.1 0.0 26.9 1.3 0.0 0.2 7.9 2.1 2.5 176.4 217.1 0.0 1.7 0.0 0.4 186.1 KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51055626-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 519.9" "Group enriched" "Detected in some" 4 "Late spermatids: 246.9;Squamous epithelial cells: 68.3" "Group enriched" "Detected in many" 4 "cervical cancer: 20.6;head and neck cancer: 42.3;melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HaCaT: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA062136: AB_2684694" "unprognostic (1.99e-3)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-2)" "unprognostic (2.18e-2)" "unprognostic (8.30e-2)" "unprognostic (7.07e-6)" "unprognostic (7.33e-2)" "unprognostic (2.53e-1)" "unprognostic (6.38e-2)" "unprognostic (7.06e-2)" 0.2 0.2 0.1 0.2 0.1 0.0 1.6 0.1 0.2 96.3 0.9 0.6 1.6 0.5 0.4 519.9 0.5 1.1 0.2 0.1 0.1 0.1 0.2 0.7 0.0 0.2 0.5 0.2 4.4 0.4 0.3 0.0 0.1 0.6 0.1 0.0 74.9 0.0 0.1 10.8 0.8 0.3 0.1 0.1 1.4 4.3 0.1 0.2 0.3 0.0 63.5 0.2 122.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 27.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.6 1.1 4.0 0.0 0.9 1.9 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.1 0.1 0.3 1.8 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.3 246.9 0.3 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.7 68.3 1.3 0.0 0.4 0.4 0.0 2.1 KLK14 KLK-L6 ENSG00000129437 "Kallikrein related peptidase 14" Q9P0G3 19 51077495-51084245 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 9.7" "Cell type enhanced" "Detected in single" "Club cells: 2.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.7;HEK 293: 2.9;U-266/84: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" CAB026228 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "CAB026228: " "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.44e-2)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (6.12e-2)" "unprognostic (4.91e-2)" "unprognostic (5.79e-2)" "unprognostic (7.84e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (8.87e-2)" "unprognostic (2.04e-8)" "unprognostic (1.93e-1)" "unprognostic (3.74e-3)" "unprognostic (1.94e-2)" "unprognostic (8.08e-2)" 0.5 0.3 2.1 0.2 2.2 0.1 1.6 2.3 3.3 4.2 1.9 0.4 1.3 0.5 0.6 0.9 0.7 0.3 0.8 2.2 1.7 0.5 0.3 0.4 0.3 2.1 1.9 1.1 0.7 0.0 0.6 0.0 2.2 0.8 0.3 0.6 0.8 0.5 0.3 9.7 0.7 0.1 1.6 0.6 0.6 0.9 2.0 0.3 0.4 0.1 0.5 0.6 3.9 2.3 1.4 0.5 0.1 0.6 0.4 0.4 0.6 0.1 0.0 0.0 0.1 1.2 1.4 0.6 0.4 0.2 0.3 10.7 0.1 0.2 0.0 0.3 2.9 0.2 0.9 0.0 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.1 0.1 0.4 0.2 0.3 0.0 0.9 0.2 0.5 0.6 1.2 1.1 0.1 0.1 0.6 0.0 0.6 0.1 0.0 0.2 1.0 0.3 0.2 0.4 0.0 0.0 0.1 0.4 0.6 0.2 2.6 5.5 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.3 3.3 2.2 1.7 2.1 1.9 2.2 1.6 2.0 2.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLK15 "ACO, HSRNASPH, prostinogen" ENSG00000174562 "Kallikrein related peptidase 15" Q9H2R5 19 50825289-50837213 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.2;salivary gland: 5.6" "Cell type enhanced" "Detected in some" "Early spermatids: 5.5;Intestinal goblet cells: 34.6;Late spermatids: 8.8;Spermatocytes: 15.0;Spermatogonia: 9.5" "Group enriched" "Detected in some" 4 "prostate cancer: 3.5;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA019802 Uncertain "Secreted to blood" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA019802: AB_1852601" "unprognostic (6.06e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-2)" "unprognostic (2.90e-1)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.2 0.0 5.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.5 0.0 0.0 0.1 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 34.6 0.0 0.0 0.0 8.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 9.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 87 "prostate: 566.2" "Cell type enriched" "Detected in some" 40 "Prostatic glandular cells: 777.2" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 3.5;NB-4: 5.6" HPA000764 Supported "Secreted in male reproductive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" 0.7 1.1 3.2 1.2 2.3 6.4 0.5 5.2 4.3 0.2 2.2 0.4 1.5 0.6 1.1 0.5 0.3 0.2 0.3 2.6 2.2 0.4 0.8 0.5 1.0 2.2 3.1 0.4 0.0 0.8 0.0 0.2 2.9 566.2 0.3 1.7 1.9 0.4 1.0 0.8 1.0 0.1 0.6 0.7 0.5 3.0 2.4 0.0 1.9 0.0 0.2 0.2 0.0 6.3 0.9 0.6 0.3 0.7 0.0 0.4 3.5 0.2 0.1 0.1 0.1 0.3 0.4 1.0 0.1 0.0 0.3 0.9 0.1 0.0 0.1 0.9 0.6 0.0 0.7 0.0 0.0 0.1 1.7 0.2 0.1 0.1 0.2 0.2 0.0 0.6 0.7 0.9 0.2 1.0 0.6 5.6 0.5 0.9 0.0 0.4 0.0 1.6 0.0 1.1 0.5 0.5 0.1 0.7 0.6 0.1 0.5 0.2 0.4 0.6 1.0 2.6 0.9 0.8 1.8 0.4 1.0 0.6 0.7 0.4 0.6 0.5 0.3 0.3 0.2 0.3 0.2 0.3 0.1 0.6 0.2 0.4 1.7 0.4 0.2 0.5 0.1 0.2 3.2 2.3 5.2 4.3 2.6 2.2 2.2 3.1 2.9 0.6 2.4 6.3 0.0 0.0 0.6 0.0 0.2 0.3 10.2 0.0 0.0 0.0 16.1 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 5.2 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 777.2 0.0 0.1 0.0 0.0 0.0 0.0 1.8 19.3 7.2 0.0 0.9 0.0 0.6 1.7 0.0 12.0 KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 320 "prostate: 8011.8" "Cell type enriched" "Detected in some" 77 "Prostatic glandular cells: 3438.6" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 173 "BEWO: 31.7;NB-4: 27.8;RPMI-8226: 19.3;SH-SY5Y: 10.5;U-2197: 10.7" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" NA NA 7000000 "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" 4.3 7.6 0.0 5.6 0.0 0.0 9.0 0.0 0.0 0.5 0.0 2.6 4.8 1.6 14.4 0.2 4.0 0.0 0.5 0.0 0.0 1.4 1.5 1.2 1.7 0.0 0.0 0.3 0.9 0.6 0.2 0.3 0.0 8011.8 1.1 0.0 4.5 25.0 0.3 0.5 3.7 0.0 0.0 0.2 1.0 6.9 0.0 0.0 0.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 19.3 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 12.4 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.4 2.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.1 9.0 0.0 0.0 0.0 1.8 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 3438.6 0.1 0.1 0.0 0.0 0.0 0.0 6.9 0.1 0.0 0.0 0.0 0.0 4.2 0.2 0.4 44.6 KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906352-50910738 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 32 "prostate: 286.4" "Cell type enriched" "Detected in some" 15 "Prostatic glandular cells: 106.1" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.4;HaCaT: 7.9;OE19: 7.3;SK-BR-3: 5.1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.5" HPA051839 Enhanced "Secreted in male reproductive system" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" "HPA051839: AB_2681632" "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" 0.4 2.9 0.4 1.5 0.3 1.1 1.7 1.7 1.2 6.5 0.0 3.0 7.3 4.4 1.1 2.1 0.6 1.0 0.1 0.3 0.8 0.6 1.2 0.3 0.8 1.6 0.8 0.1 0.9 1.0 0.0 0.3 1.6 286.4 3.6 0.5 4.8 2.7 3.5 8.9 5.1 0.3 0.5 0.3 1.9 1.2 0.6 0.1 3.8 1.3 0.8 1.2 0.2 0.5 4.1 1.6 0.2 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.5 6.4 0.4 0.3 0.1 0.2 7.9 0.0 4.2 0.0 1.1 1.1 1.3 3.8 1.4 0.0 1.4 1.7 0.0 1.9 0.0 0.0 0.2 0.0 0.3 0.7 3.3 0.0 1.0 0.1 2.0 0.1 7.3 0.3 0.3 0.4 0.9 0.0 2.6 0.0 0.4 0.3 5.1 0.0 0.2 4.0 0.3 0.9 0.2 0.2 1.0 0.2 2.0 0.9 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.7 1.2 0.3 0.8 1.6 0.8 1.6 0.5 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.6 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 2.6 0.1 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 0.0 0.0 0.0 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 106.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 3.3 1.0 2.6 KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 202.7" "Group enriched" "Detected in some" 4 "Early spermatids: 85.4;Late spermatids: 193.2" "Group enriched" "Detected in many" 5 "head and neck cancer: 73.1;melanoma: 32.1;ovarian cancer: 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "A-431: 485.1;HaCaT: 455.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014343, CAB025503, CAB026341, HPA073512" Enhanced "Secreted in other tissues" NA NA 2500000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "CAB025503: , CAB026341: , HPA014343: AB_1852603, HPA073512: " "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavorable (3.85e-6)" 4.6 0.0 1.1 0.0 1.1 0.0 30.2 0.4 2.6 15.6 0.6 0.0 0.1 0.1 0.0 23.0 0.5 0.0 0.2 1.1 0.8 0.5 0.1 6.1 0.0 1.0 1.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 23.6 0.0 1.1 202.7 0.0 0.0 0.5 0.3 0.0 14.2 1.6 0.1 0.1 0.0 0.6 0.0 13.5 0.7 485.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.1 455.4 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 1.1 0.0 1.5 0.1 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.4 2.6 1.1 0.8 1.0 1.0 1.0 0.5 1.6 0.7 0.2 16.0 0.0 0.0 0.0 26.8 1.8 2.4 12.0 0.0 33.0 27.2 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 85.4 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 193.2 1.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 1.6 0.8 2.8 10.9 0.0 0.3 0.0 0.0 0.1 KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 253.0;esophagus: 94.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 23.9;Breast myoepithelial cells: 16.1;Collecting duct cells: 11.0;Oligodendrocytes: 87.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 575.5;CAPAN-2: 1346.5" "Region enhanced" "Detected in all" "pons and medulla: 167.8" "Region enhanced" "Detected in many" "spinal cord: 371.7" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" Yes No 10000000 "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (1.27e-4)" 0.2 0.0 71.8 0.0 135.8 0.0 7.2 170.8 119.8 53.1 45.6 0.1 0.2 1.5 0.4 94.2 28.9 3.5 0.0 72.9 94.3 20.4 0.0 0.0 0.0 213.8 130.8 0.8 0.0 0.0 0.7 0.0 182.1 0.1 0.0 0.0 15.8 2.2 0.0 9.9 0.0 0.0 123.6 5.8 0.1 0.9 118.1 1.5 0.0 0.0 36.4 0.0 27.4 253.0 575.5 0.0 0.0 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 67.7 1346.5 0.0 8.1 0.0 0.6 8.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.1 131.0 2.2 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 5.6 18.2 1.0 1.9 0.0 1.1 46.3 0.0 1.3 0.0 0.4 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 135.8 170.8 119.8 72.9 94.3 213.8 130.8 182.1 123.6 118.1 253.0 0.2 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 0.0 23.9 16.1 0.3 0.0 1.7 11.0 0.0 0.1 0.4 0.0 0.0 0.1 2.3 0.6 7.5 0.4 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 87.9 7.8 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 1.6 0.0 0.3 0.1 0.0 0.0 2.4 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Basal keratinocytes: 5.0;Basal squamous epithelial cells: 4.6;Breast glandular cells: 9.4;Breast myoepithelial cells: 10.4;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 10.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.0;CAPAN-2: 8.0;HaCaT: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 7.1 0.1 8.4 0.1 9.2 0.3 11.2 0.9 7.4 19.7 1.0 0.1 0.5 0.7 0.2 94.7 16.3 1.3 0.2 6.5 1.4 12.1 0.1 3.1 0.0 4.3 1.4 0.1 0.1 0.3 0.7 0.0 4.9 0.1 0.0 0.1 21.6 0.2 1.0 201.2 0.0 0.2 2.1 0.8 0.3 0.3 7.4 0.9 0.2 0.0 10.9 0.0 30.9 3.0 5.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.8 8.0 0.0 1.1 0.0 0.1 31.7 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 8.4 9.2 0.9 7.4 6.5 1.4 4.3 1.4 4.9 2.1 7.4 3.0 0.0 6.4 1.1 0.0 0.0 5.0 0.1 0.5 4.6 0.0 9.4 10.4 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 5.9 10.7 0.0 0.1 0.0 0.1 2.7 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 66.0;Suprabasal keratinocytes: 180.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 88.3;CAPAN-2: 112.2;HaCaT: 83.5" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 5.7 0.0 0.1 0.0 0.0 0.0 8.4 0.8 0.7 24.7 0.2 0.0 0.0 0.9 0.4 118.0 13.2 0.1 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.7 0.2 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 17.1 0.1 0.7 87.1 0.0 0.1 0.0 0.2 0.1 1.2 0.2 1.1 0.5 0.0 9.6 0.0 47.2 0.5 88.3 0.0 0.0 0.6 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.7 112.2 0.0 2.2 0.0 0.1 83.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 10.3 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.7 0.0 0.0 0.7 0.2 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.3 66.0 0.0 0.4 14.8 0.0 13.0 15.6 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.7 11.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 5.0 1.8 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 2.8 6.2 21.1 180.1 0.0 0.2 0.0 0.2 0.1 KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51002508-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.0" CAB025049 Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "CAB025049: " "unprognostic (3.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 KMT2A "ALL-1, CXXC7, HRX, HTRX1, MLL, MLL1A, TRX1" ENSG00000118058 "Lysine methyltransferase 2A" Q03164 11 118436490-118526832 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017794, CAB024270, HPA044910" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB017794: , CAB024270: , HPA044910: AB_2679141" "unprognostic (6.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.83e-1)" "unprognostic (4.56e-1)" "unprognostic (4.96e-2)" "unprognostic (1.72e-3)" "unprognostic (4.52e-3)" "unprognostic (6.07e-2)" "unprognostic (1.61e-1)" "unprognostic (8.46e-2)" "unprognostic (3.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.91e-3)" "unprognostic (7.90e-2)" "unprognostic (3.73e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" 9.9 6.7 8.0 8.5 8.6 19.5 9.9 21.2 9.3 10.3 1.6 10.8 5.4 10.7 8.2 6.8 10.3 6.4 6.5 7.4 9.6 6.7 6.0 10.5 12.4 6.3 6.3 21.2 11.1 9.8 10.2 5.6 6.6 9.2 6.4 23.9 9.4 8.4 7.4 10.4 9.8 7.6 3.2 9.7 8.2 5.3 7.0 14.1 9.9 8.4 11.3 10.7 9.3 11.9 17.9 8.6 20.1 14.5 11.1 16.1 6.2 8.7 11.8 9.0 9.6 17.3 11.4 23.1 15.9 10.8 14.6 16.0 22.9 7.2 17.9 26.0 10.0 45.7 8.9 9.3 6.1 28.5 7.8 7.2 7.4 20.3 24.0 8.9 12.8 13.3 32.8 18.8 9.2 12.7 18.2 12.7 13.6 6.6 13.7 13.8 21.9 6.9 9.8 13.8 18.0 11.8 22.0 6.7 3.9 9.8 11.9 9.1 20.4 14.1 12.7 9.4 14.7 5.1 4.4 15.6 4.7 17.6 8.3 2.1 0.6 1.9 1.6 0.6 1.6 2.5 1.8 1.5 0.3 1.8 1.8 1.2 0.5 2.0 0.7 1.4 1.7 0.4 8.0 8.6 21.2 9.3 7.4 9.6 6.3 6.3 6.6 3.2 7.0 11.9 87.1 70.5 65.8 93.4 83.4 86.9 67.6 29.4 64.9 158.1 76.8 73.9 44.5 40.0 32.2 38.6 152.2 13.9 81.0 26.2 3.9 33.0 10.1 62.1 101.4 74.4 66.4 67.3 146.0 25.6 10.2 65.6 44.4 85.2 29.0 57.5 60.0 27.3 16.8 195.2 170.1 29.6 20.3 37.0 63.7 5.8 66.8 44.8 42.7 62.8 49.9 98.9 78.2 106.6 131.9 28.2 20.1 78.6 83.3 88.3 22.7 10.5 52.7 152.4 65.7 113.4 84.6 25.5 30.7 46.3 80.6 6.0 102.8 55.8 30.6 64.8 KMT2B "CXXC10, HRX2, KIAA0304, MLL1B, MLL2, MLL4, TRX2, WBP7" ENSG00000272333 "Lysine methyltransferase 2B" Q9UMN6 19 35717973-35738878 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 64.5;Rod photoreceptor cells: 71.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006487 Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA006487: AB_1080587" "unprognostic (1.09e-2)" "unprognostic (3.53e-2)" "unprognostic (3.41e-2)" "unprognostic (7.95e-2)" "unprognostic (9.92e-2)" "unprognostic (3.53e-3)" "unprognostic (2.33e-2)" "unprognostic (4.57e-2)" "unprognostic (7.28e-2)" "unprognostic (2.07e-2)" "unprognostic (3.13e-3)" "unprognostic (2.63e-3)" "unprognostic (9.47e-3)" "unprognostic (2.10e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" 11.6 10.1 15.4 9.8 15.7 14.3 11.8 17.2 22.9 12.9 12.2 13.6 9.8 14.1 4.4 12.8 13.1 6.8 8.4 14.7 14.8 10.3 10.0 12.1 14.5 15.4 14.4 16.1 16.0 5.1 14.5 5.8 14.7 13.4 3.9 5.8 13.3 5.8 16.1 18.8 14.5 4.5 12.4 15.6 12.7 22.5 15.9 9.3 16.6 5.0 6.8 12.6 12.0 16.0 16.7 36.7 11.1 17.3 6.0 4.3 11.0 6.7 4.7 7.3 5.0 25.3 7.4 15.5 11.8 5.1 8.5 10.8 11.3 5.2 4.2 21.2 13.6 29.7 20.2 24.4 8.6 17.4 26.1 6.9 9.4 8.9 10.7 6.9 5.7 13.5 22.5 15.8 6.4 34.1 15.9 24.4 12.0 18.8 9.2 19.8 8.9 7.6 7.8 21.3 14.0 10.0 13.5 20.6 11.3 7.9 11.8 21.3 12.5 16.3 17.0 10.5 17.4 22.2 15.7 12.4 8.5 18.8 12.2 0.3 0.4 0.4 1.0 0.1 0.5 0.4 0.6 0.7 0.3 0.7 0.6 0.9 1.8 0.5 0.2 2.1 0.8 0.4 15.4 15.7 17.2 22.9 14.7 14.8 15.4 14.4 14.7 12.4 15.9 16.0 24.6 9.6 15.4 13.7 18.6 12.7 10.0 6.2 9.6 64.5 16.1 14.6 9.2 8.6 6.3 9.2 52.1 6.5 27.4 25.2 0.0 6.4 2.8 17.9 31.6 15.6 20.3 7.4 11.7 7.7 6.1 12.4 27.5 26.0 5.1 30.5 11.0 11.2 8.4 35.3 11.8 14.1 6.1 11.8 7.1 4.7 8.1 13.4 5.4 7.5 9.5 25.7 19.6 7.5 10.0 8.4 16.7 12.4 17.9 19.6 13.9 5.0 6.7 71.2 0.0 25.0 17.3 26.5 38.5 11.9 12.9 9.4 20.6 30.7 16.3 14.8 KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436641 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 363.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 15.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074736 Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA074736: AB_2686709" "unprognostic (7.75e-2)" "unprognostic (3.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.33e-2)" "unprognostic (1.31e-1)" "unprognostic (5.23e-3)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.45e-1)" "unprognostic (1.06e-1)" "prognostic favorable (8.01e-6)" "unprognostic (1.78e-1)" "unprognostic (3.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.64e-1)" 12.7 11.2 16.7 7.3 25.7 16.4 12.9 16.7 15.7 15.3 5.5 13.1 5.7 14.3 13.7 14.1 11.9 7.7 10.2 13.0 18.9 8.9 10.4 12.7 8.1 25.3 19.4 16.8 18.5 12.4 12.1 10.3 20.6 9.3 7.6 21.7 14.2 9.0 25.9 17.6 12.8 7.5 12.2 12.2 15.2 13.4 19.1 16.1 14.6 16.9 9.5 11.3 12.7 28.6 13.4 6.1 11.6 11.7 19.0 13.9 10.2 4.7 6.4 5.0 5.5 10.9 4.7 22.4 8.9 11.3 9.2 5.2 14.3 7.5 9.2 12.7 6.5 14.0 7.3 4.5 8.9 22.9 12.8 6.6 9.1 7.1 8.2 7.2 8.4 9.7 22.5 15.0 11.7 12.7 14.8 11.1 6.8 8.5 7.9 9.5 12.3 8.4 5.8 10.9 19.6 12.8 13.4 15.8 6.3 10.6 4.6 15.7 12.8 8.0 4.4 9.0 8.9 15.3 7.7 22.4 10.7 14.7 8.4 6.1 3.0 4.4 1.9 2.7 1.6 6.9 2.0 1.5 1.4 3.9 1.9 1.4 15.2 2.2 2.6 3.7 1.3 0.8 16.7 25.7 16.7 15.7 13.0 18.9 25.3 19.4 20.6 12.2 19.1 28.6 62.4 76.9 71.9 292.8 75.0 89.1 38.3 31.5 62.0 89.0 59.6 35.2 65.8 44.3 72.4 46.0 173.0 38.0 61.9 61.7 5.9 37.6 32.1 94.4 92.1 58.9 67.9 55.5 180.7 33.1 51.7 58.3 89.2 200.5 65.2 52.8 56.7 46.0 33.7 80.8 172.2 53.5 42.7 54.7 79.6 17.3 67.4 90.5 42.7 202.4 77.1 57.7 59.8 299.6 363.2 37.6 49.0 60.2 90.3 53.6 36.3 14.7 46.9 73.0 26.3 83.0 55.5 42.3 33.9 80.9 96.3 127.2 76.8 54.8 39.1 61.4 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018978-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 19.9 21.9 14.0 17.0 14.4 62.1 20.3 14.7 18.1 20.2 3.8 21.3 13.2 26.9 14.4 25.5 24.1 11.7 23.7 12.1 9.1 18.2 20.5 25.1 17.5 9.3 8.2 25.3 33.2 22.9 25.4 16.2 8.6 19.2 14.7 48.0 22.1 16.2 44.9 30.4 27.9 15.5 3.1 36.6 25.5 23.6 12.7 29.0 26.5 21.9 17.2 19.4 19.4 13.4 32.3 31.9 31.0 24.7 29.3 20.4 32.6 17.3 17.1 20.3 10.9 54.8 14.1 33.4 21.2 23.9 14.0 21.5 38.1 19.9 17.7 22.4 26.7 47.2 37.7 29.9 20.5 59.1 43.2 18.4 25.8 30.7 32.0 27.3 31.8 33.2 55.1 19.2 23.7 37.4 26.8 48.0 29.9 45.4 25.0 37.4 22.4 12.0 18.1 37.2 24.6 21.2 28.1 25.5 19.5 26.1 24.0 44.1 49.8 15.5 30.7 14.5 30.5 24.8 20.9 31.7 17.1 28.0 12.5 0.5 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 1.5 0.5 0.0 0.2 0.0 0.1 14.0 14.4 14.7 18.1 12.1 9.1 9.3 8.2 8.6 3.1 12.7 13.4 12.9 9.6 19.1 17.6 13.3 14.0 7.8 8.1 14.2 26.8 12.1 7.1 7.8 12.8 10.9 18.4 52.1 8.2 15.3 12.3 1.9 6.3 2.8 10.7 12.7 13.2 13.1 16.0 17.4 6.0 6.0 8.8 24.5 13.1 8.2 23.3 17.9 13.0 9.8 21.9 16.5 10.0 6.1 15.7 18.4 2.4 9.6 15.4 10.6 15.0 14.9 6.4 17.5 12.5 19.8 8.8 9.5 10.9 10.1 11.0 13.3 4.5 9.0 38.4 6.6 14.4 12.5 6.5 3.8 18.9 17.6 11.4 15.3 10.8 10.3 9.6 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KRAS "KRAS1, KRAS2" ENSG00000133703 "KRAS proto-oncogene, GTPase" P01116 12 25205246-25250936 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049830 Approved NA NA 3300000 "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "HPA049830: AB_2680903" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.86e-3)" "unprognostic (1.08e-2)" "unprognostic (7.39e-2)" "unprognostic (1.51e-1)" "unprognostic (1.47e-2)" "unprognostic (3.74e-2)" "unprognostic (1.79e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (3.59e-4)" "unprognostic (6.42e-2)" "prognostic favorable (2.75e-5)" "unprognostic (1.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.81e-2)" "unprognostic (9.97e-2)" 11.8 9.1 11.0 16.2 12.2 27.8 10.0 11.7 12.3 9.5 4.6 22.0 14.0 11.0 6.8 19.3 7.4 13.1 8.6 12.5 12.0 11.7 15.3 13.2 17.9 8.5 9.7 8.0 12.6 11.1 5.7 17.0 8.7 11.8 23.0 22.7 11.9 8.3 7.6 13.6 19.5 13.6 8.1 12.0 20.3 8.9 12.9 17.2 10.8 10.3 17.4 16.2 11.4 8.6 15.9 14.3 39.4 20.7 14.1 19.9 68.9 17.3 22.8 18.0 21.9 51.5 30.7 38.7 10.4 32.0 23.4 18.6 44.9 17.3 34.3 26.7 15.0 37.6 17.6 15.6 15.8 32.8 25.6 18.1 25.5 21.9 20.2 33.6 27.1 28.7 28.0 17.3 27.6 14.1 46.8 56.6 87.6 25.3 7.4 43.4 39.9 59.9 27.2 22.4 11.2 32.4 20.5 24.9 21.8 97.4 28.9 26.9 28.1 18.7 24.8 38.2 22.0 16.4 28.5 41.9 15.4 20.0 15.0 31.2 8.1 13.7 11.6 16.4 7.9 10.7 10.1 13.1 7.9 10.5 13.8 12.4 19.2 11.2 22.4 7.8 7.6 5.8 11.0 12.2 11.7 12.3 12.5 12.0 8.5 9.7 8.7 8.1 12.9 8.6 73.7 48.1 32.1 16.6 90.8 100.9 96.4 57.2 72.3 63.4 59.9 38.0 16.3 64.3 53.6 38.6 73.0 94.2 66.0 161.9 58.7 77.5 3.9 45.4 40.8 77.3 78.8 60.2 42.0 91.8 21.4 50.1 98.4 53.4 24.1 26.6 77.8 56.9 51.5 92.5 45.3 92.9 36.7 53.9 83.7 5.9 40.7 75.3 62.2 28.1 82.9 41.7 49.4 19.6 16.6 114.2 104.7 51.6 85.0 130.1 63.0 52.3 42.5 65.8 26.3 53.7 52.2 53.0 40.3 93.0 155.7 139.1 83.0 36.5 96.7 176.9 KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40925.1;vagina: 13409.3" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 16844.0" "Group enriched" "Detected in many" 5 "cervical cancer: 899.2;head and neck cancer: 758.7;urothelial cancer: 504.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 93 "A-431: 2462.5;HaCaT: 1626.2" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 680000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000133: , HPA030877: AB_2673641, HPA069771: AB_2732141" "unprognostic (1.45e-1)" "unprognostic (6.23e-2)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (9.30e-5)" "unprognostic (7.30e-3)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (5.81e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.45e-6)" "unprognostic (1.80e-1)" "unprognostic (2.76e-1)" "unprognostic (3.04e-2)" "unprognostic (4.33e-1)" 7.7 7.5 0.0 0.0 0.1 6.8 5.1 0.0 0.0 6884.6 0.0 5.6 0.1 10.2 0.0 40925.1 7.0 8.8 9.2 0.0 0.1 5.6 12.8 6.0 0.3 0.0 0.0 9.9 17.2 0.0 26.9 0.0 0.0 115.2 0.0 0.0 6881.1 3.8 9.8 20.5 8.5 14.2 0.0 7.7 31.3 6.9 0.0 13.6 6.1 0.0 1855.2 924.7 13409.3 0.0 2462.5 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.6 0.8 7.1 0.6 0.0 0.0 1626.2 0.0 0.4 0.0 1.4 0.0 4.5 21.8 0.0 0.0 1.7 1.3 0.0 0.8 0.0 0.0 0.3 0.0 0.0 5.4 1.2 0.0 1.3 0.1 0.1 0.1 14.8 0.3 0.2 1.2 0.3 0.0 10.7 0.0 0.0 1.9 2.0 7.7 0.0 2.3 6.4 5.1 0.0 0.4 0.0 6.6 0.3 6.3 5.8 1.9 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.0 1.1 0.0 0.9 2.8 545.6 17.1 146.8 0.0 2.3 4.6 0.6 1.5 94.5 0.0 0.0 0.1 0.2 0.6 0.0 0.0 1.2 2.7 0.2 11.4 1.2 5.5 0.0 0.0 0.5 12.6 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 8.2 0.0 0.0 3.2 55.9 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.7 286.6 27.1 227.9 0.1 0.1 3.3 0.0 0.0 0.0 16.9 0.2 0.6 16844.0 1.6 0.4 8.8 0.0 0.4 3645.4 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 419.1;esophagus: 1156.7;skin 1: 1319.5;vagina: 423.3" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 2789.9;Basal squamous epithelial cells: 8290.4;Squamous epithelial cells: 4637.9" "Cancer enhanced" "Detected in many" "cervical cancer: 178.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "HaCaT: 1156.8;hTCEpi: 1001.5" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 480000000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Nucleoplasm "HPA023910: AB_1852205, HPA024554: AB_1852207" "prognostic favorable (4.50e-4)" "unprognostic (9.14e-2)" "unprognostic (3.28e-2)" "unprognostic (1.19e-3)" "unprognostic (3.57e-2)" "unprognostic (8.84e-2)" "unprognostic (6.12e-3)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "unprognostic (8.65e-3)" "unprognostic (9.91e-3)" "unprognostic (2.09e-1)" "unprognostic (2.24e-11)" "unprognostic (6.91e-3)" "unprognostic (2.62e-1)" "unprognostic (1.33e-5)" "unprognostic (5.35e-2)" 4.7 0.3 0.1 0.2 0.0 0.7 419.1 0.0 0.1 148.2 0.2 1.1 1.5 0.3 2.2 1156.7 32.4 2.8 0.7 0.1 0.0 0.3 0.6 4.3 0.0 0.1 0.1 0.4 1.4 0.0 1.2 0.3 0.1 182.8 1.6 0.0 140.0 4.1 0.7 1319.5 2.3 0.1 0.0 0.3 1.6 8.0 0.1 93.7 0.5 0.0 77.6 9.5 423.3 0.1 56.4 7.4 0.0 0.0 0.0 0.0 0.7 5.3 1.3 0.3 0.2 5.9 20.2 0.0 1.8 0.6 14.0 1156.8 0.0 41.8 0.2 0.6 0.0 0.0 7.7 1.9 0.0 0.1 4.7 0.0 1001.5 2.2 6.9 2.7 3.4 0.0 0.3 0.5 0.2 3.5 0.1 0.5 0.0 3.9 6.2 0.0 0.0 104.9 3.3 5.9 2.6 0.1 1.1 15.0 1.2 0.3 20.3 0.0 18.6 0.3 2.8 0.3 2.2 0.1 0.1 0.0 8.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 6.1 12.8 10.3 0.0 2.7 1309.8 2789.9 1190.9 8290.4 0.6 577.7 670.3 0.8 5.7 287.5 1.8 0.0 0.7 16.9 18.3 1.9 8.5 117.6 4.1 0.7 22.9 4.8 0.0 0.1 7.5 7.7 21.7 4.6 8.2 2.5 0.0 0.0 0.0 0.4 0.0 0.1 10.3 189.2 0.0 61.7 44.4 1.5 17.2 320.2 0.0 0.0 0.2 0.0 0.0 0.1 14.1 10.5 0.4 88.7 872.9 8.6 0.1 57.7 0.6 0.0 0.4 32.1 0.6 0.8 4637.9 193.6 1.2 21.6 0.1 7.2 906.0 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT18 ENSG00000111057 "Keratin 18" P05783 12 52948871-52952906 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 3698.8;Ductal cells: 6583.8;Exocrine glandular cells: 4826.1;Extravillous trophoblasts: 5496.7;Pancreatic endocrine cells: 6071.5;Syncytiotrophoblasts: 7643.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 76.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 76.7" "Cell line enhanced" "Detected in many" "A549: 5639.4;BEWO: 3818.0;CACO-2: 6249.4;CAPAN-2: 4576.4;MCF7: 8470.0;SK-BR-3: 4583.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 12.1" "CAB000008, CAB000030, HPA001605" Enhanced Supported Cytosol NA NA 140000000 "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" Cytosol "CAB000008: , CAB000030: , HPA001605: AB_2666381" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (7.26e-3)" "unprognostic (4.09e-3)" "prognostic unfavorable (5.06e-4)" "unprognostic (8.81e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (3.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" 170.3 29.0 2.6 77.5 1.4 1.5 209.8 5.3 1.6 243.5 34.8 424.1 324.3 27.8 226.0 118.4 193.5 180.6 38.3 2.2 6.9 247.2 519.5 177.8 8.6 26.1 4.3 16.4 570.2 79.5 251.9 474.5 30.3 183.3 492.3 0.6 323.4 129.5 2.1 44.5 370.7 23.4 2.5 28.5 289.9 8.3 13.9 10.3 244.1 1.4 27.8 199.7 62.2 2.5 2065.1 5639.4 1.1 7.9 0.7 1.1 3818.0 313.3 349.5 368.4 104.6 6249.4 4576.4 1.4 839.8 318.4 196.5 487.2 79.1 2228.5 217.9 2.6 138.2 19.4 865.7 1743.9 942.1 0.6 1.3 13.6 202.9 323.8 437.1 1046.9 399.0 3.4 511.4 0.2 0.3 8470.0 3.8 37.3 471.0 2740.1 457.9 3.0 0.3 236.1 1803.3 1144.9 65.6 3.7 512.7 4583.8 18.8 2696.0 2446.8 6.6 137.9 5.0 441.8 6.9 68.3 1.1 7.3 4.3 0.9 1.2 36.4 76.7 0.3 2.4 0.6 0.2 2.2 4.6 4.5 1.2 2.2 7.4 11.1 4.1 3.2 2.5 0.0 0.1 0.4 2.9 2.6 1.4 5.3 1.6 2.2 6.9 26.1 4.3 30.3 2.5 13.9 2.5 14.4 862.2 286.4 0.3 29.8 14.8 1605.7 912.1 447.3 0.1 814.6 615.6 5.3 1252.5 877.3 623.5 0.0 3698.8 14.2 1942.9 275.9 6583.8 1.0 462.3 60.3 77.8 642.3 15.4 0.0 4826.1 5496.7 203.5 971.5 742.4 48.9 51.2 57.1 610.9 308.3 1.7 0.0 2492.6 1969.3 9.8 13.8 3.8 10.5 28.3 208.1 1.0 41.5 6.2 0.0 0.0 0.0 6071.5 2164.1 0.0 13.7 1205.1 1912.3 718.5 500.8 0.6 0.0 0.6 298.6 2.7 26.0 395.7 6.7 7643.5 38.1 45.0 1635.0 1512.1 KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 889.0;salivary gland: 810.7;urinary bladder: 781.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 7444.0;Club cells: 5055.9;Ductal cells: 4717.9;Extravillous trophoblasts: 6919.3;Pancreatic endocrine cells: 7374.9;Proximal enterocytes: 8623.3;Urothelial cells: 5959.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 1945.3;HBEC3-KT: 2945.0;MCF7: 2220.9;RT4: 3146.7;SK-BR-3: 5446.1;T-47d: 3674.2" "Not detected" "Not detected" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" 89.3 18.7 2.0 61.7 2.4 0.3 403.3 7.9 2.5 250.0 1.6 525.7 348.3 57.9 72.0 889.0 176.1 298.6 13.5 1.5 1.7 141.8 7.7 204.1 0.4 1.6 2.9 74.4 48.8 14.3 15.6 175.1 2.2 208.3 359.2 0.1 810.7 194.2 1.3 141.9 776.1 46.5 1.4 1.2 631.5 3.4 1.8 127.8 28.3 1.6 98.3 781.4 317.0 1.8 2.6 343.4 0.0 6.3 0.7 1.8 1169.3 412.1 0.5 12.8 2.9 992.6 1945.3 0.4 393.3 199.0 1.5 1044.6 0.1 2945.0 2.5 0.8 10.4 0.2 213.4 692.3 30.3 0.0 82.0 0.7 524.9 9.0 0.4 0.2 26.2 0.0 148.4 2.5 0.1 2220.9 5.9 3.0 18.5 1323.5 492.7 2.9 0.1 5.8 1335.4 3146.7 40.0 1.7 3.3 5446.1 0.1 266.5 3674.2 0.3 1.7 3.6 6.1 7.7 0.7 1.1 0.8 2.0 1.5 0.3 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.0 2.4 7.9 2.5 1.5 1.7 1.6 2.9 2.2 1.4 1.8 1.8 10.5 673.1 185.5 0.0 17.8 5.2 4317.3 7444.0 1715.8 0.0 1393.0 867.5 2.9 662.0 5055.9 892.0 0.0 1160.8 20.5 3599.6 1.9 4717.9 0.1 737.2 102.8 41.9 362.5 0.0 0.1 2589.9 6919.3 171.8 1571.4 1010.7 94.6 1.0 1.1 0.7 179.0 0.0 0.1 1382.4 2720.0 2.6 2.5 2.6 37.9 25.5 190.3 1.0 30.0 0.8 0.0 0.0 0.0 7374.9 3399.6 88.8 19.9 2228.8 8623.3 26.7 1954.3 0.0 0.0 0.0 240.0 1.1 1.6 1302.6 1.1 2127.5 36.1 4.8 1619.0 5959.8 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT8 "CARD2, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1335.5;stomach 1: 800.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4302.8;Ductal cells: 6037.3;Exocrine glandular cells: 5457.6;Extravillous trophoblasts: 5323.4;Pancreatic endocrine cells: 5278.1;Paneth cells: 4937.3;Proximal enterocytes: 6802.6;Syncytiotrophoblasts: 5268.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 6130.6;BEWO: 3998.7;CACO-2: 7686.4;CAPAN-2: 4774.8;MCF7: 10521.8;SK-BR-3: 5126.4;T-47d: 4325.7" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 10 "spinal cord: 44.0" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 1700000000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Intermediate filaments" "CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (2.76e-2)" "unprognostic (4.86e-3)" "unprognostic (3.10e-2)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (8.99e-2)" "unprognostic (2.08e-2)" "unprognostic (2.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.68e-1)" "unprognostic (1.19e-2)" 135.0 43.6 2.2 158.6 1.3 1.0 113.8 2.0 1.6 183.4 21.3 1079.2 1112.0 34.7 66.4 48.2 134.3 217.5 147.8 1.9 1.9 240.2 463.9 172.5 7.9 8.3 4.5 10.3 654.1 59.9 278.7 368.7 8.8 151.6 564.2 0.4 318.0 73.6 1.5 49.3 1335.5 50.6 0.4 16.3 800.1 7.6 4.9 47.6 237.5 0.3 13.8 209.0 36.7 1.7 2787.7 6130.6 0.2 7.8 0.7 3.2 3998.7 11.1 47.9 6.1 6.3 7686.4 4774.8 1.1 1130.2 14.7 6.9 947.1 17.6 752.6 5.9 4.6 130.8 4.3 1184.4 2234.2 212.8 1.2 2.4 9.5 12.6 14.8 50.8 419.9 17.0 1.0 484.7 1.7 0.1 10521.8 6.5 10.6 418.5 2740.6 132.8 3.8 2.2 15.2 1198.1 1354.5 129.9 5.0 1063.2 5126.4 7.8 1263.8 4325.7 10.5 18.8 5.7 443.4 9.3 10.0 1.6 7.0 7.6 3.3 1.7 13.4 1.3 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.1 0.7 0.2 0.1 0.1 0.4 0.5 0.1 1.7 0.1 0.2 2.2 1.3 2.0 1.6 1.9 1.9 8.3 4.5 8.8 0.4 4.9 1.7 7.7 400.6 176.5 0.3 26.9 6.0 1948.0 684.7 303.3 2.3 521.6 342.8 30.2 1069.5 734.8 491.1 0.0 2208.2 8.5 4302.8 297.4 6037.3 13.9 419.2 41.0 42.3 942.5 8.6 0.5 5457.6 5323.4 94.7 1740.1 557.1 76.3 88.0 24.3 310.9 252.2 1.7 0.5 2876.3 1625.5 9.9 7.2 69.9 8.1 22.2 131.6 0.0 55.0 3.4 1.0 1.0 0.3 5278.1 4937.3 1.9 6.6 994.7 6802.6 569.1 594.8 4.3 0.0 2.2 167.4 2.0 11.4 258.9 1.7 5268.8 33.4 13.4 2337.3 1542.5 KTN1 "CG1, KIAA0004, KNT" ENSG00000126777 "Kinectin 1" Q86UP2 14 55559072-55701526 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003178, CAB015331, HPA017876" Enhanced Enhanced "Endoplasmic reticulum" NA NA 55000 "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "CAB015331: , HPA003178: AB_1079218, HPA017876: AB_1852652" "unprognostic (7.00e-3)" "unprognostic (2.99e-2)" "unprognostic (8.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.83e-5)" "prognostic unfavorable (3.76e-4)" "unprognostic (1.75e-1)" "unprognostic (1.21e-2)" "unprognostic (1.01e-1)" "unprognostic (9.08e-2)" "unprognostic (8.72e-2)" "prognostic favorable (1.01e-6)" "unprognostic (1.27e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" 81.6 77.7 90.8 52.8 98.9 36.1 81.6 92.8 106.3 61.4 165.0 97.4 43.4 58.1 97.1 72.7 53.2 58.6 134.6 81.0 94.2 104.0 106.6 67.0 61.8 100.2 95.3 63.9 67.2 143.0 67.4 69.4 100.7 77.5 90.8 127.9 73.5 73.5 378.2 137.6 53.2 60.3 95.2 53.4 61.1 145.1 99.4 54.7 107.7 281.6 61.0 113.1 55.2 110.3 200.5 133.4 100.3 106.5 132.8 127.3 140.2 159.7 127.3 97.2 85.2 89.4 233.9 152.8 213.4 166.7 102.7 347.2 122.5 138.2 162.7 251.9 65.2 109.1 223.0 174.4 126.3 160.3 83.3 119.1 124.6 122.1 208.4 208.3 161.9 122.2 107.4 88.1 189.0 154.6 141.3 95.0 76.8 91.1 194.3 109.6 258.2 73.5 244.8 307.0 122.4 100.0 245.8 113.2 143.2 201.7 115.3 101.7 230.0 193.9 250.4 100.0 151.2 38.9 55.9 110.4 229.4 93.4 109.5 117.0 42.7 48.0 56.2 40.3 54.7 95.6 69.4 65.8 44.0 106.6 71.1 62.1 29.6 64.9 52.6 185.8 48.4 16.0 90.8 98.9 92.8 106.3 81.0 94.2 100.2 95.3 100.7 95.2 99.4 110.3 363.1 307.7 239.8 72.5 171.7 654.5 285.8 215.6 270.9 206.5 460.6 348.7 852.7 270.2 214.7 428.6 360.7 155.1 194.9 575.2 31.3 249.7 721.9 351.3 186.6 345.0 224.0 165.3 93.9 304.0 199.1 211.9 95.3 298.1 134.9 384.5 295.9 401.7 116.8 326.4 112.1 226.4 207.5 181.3 261.6 377.9 248.5 168.9 172.5 104.9 194.3 449.2 142.2 90.0 139.8 341.2 325.7 441.6 184.6 283.5 152.6 109.3 319.3 400.9 335.2 333.5 292.1 694.3 386.4 217.8 723.0 164.7 168.3 162.4 282.4 328.0 LALBA LYZL7 ENSG00000167531 "Lactalbumin alpha" P00709 12 48567684-48570066 "Cancer-related genes, Metabolic proteins, Predicted secreted proteins" "Lactose biosynthesis" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 926 "breast: 2187.5" "Cell type enriched" "Detected in some" 160 "Breast glandular cells: 48911.9" "Cancer enriched" "Detected in single" 599 "breast cancer: 29.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026343, HPA029855, HPA029856" Enhanced "Secreted in female reproductive system" NA NA 91000 "Cluster 5: Breast - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "CAB026343: , HPA029855: AB_2673222, HPA029856: AB_10671362" "unprognostic (7.85e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 2187.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.6 0.0 0.0 0.0 46.7 0.0 0.0 0.0 0.0 0.0 48911.9 305.6 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.0 0.6 0.0 0.0 15.9 0.0 0.0 0.1 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 58.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.7 0.0 0.0 0.0 32.6 0.0 0.0 0.0 LAMB1 CLM ENSG00000091136 "Laminin subunit beta 1" P07942 7 107923799-108003213 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 185.6;Fibroblasts: 99.6;Peritubular cells: 141.8;Theca cells: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 593.0;ASC TERT1: 815.3;HSkMC: 779.6;TIME: 547.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004056, HPA004132, CAB004256" Enhanced "Secreted to extracellular matrix" NA NA 250000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" "CAB004256: AB_627867, HPA004056: AB_1079226, HPA004132: AB_1079225" "unprognostic (2.39e-1)" "unprognostic (6.45e-3)" "unprognostic (2.01e-1)" "unprognostic (6.75e-2)" "unprognostic (3.45e-3)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (3.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "unprognostic (3.44e-1)" "unprognostic (5.01e-2)" "unprognostic (2.87e-2)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-1)" 141.4 21.8 1.2 26.5 1.6 0.1 74.1 0.9 1.7 46.4 23.0 87.0 29.3 78.9 3.3 25.2 44.1 53.4 53.9 2.4 0.7 81.4 14.7 104.3 9.4 0.0 0.8 29.4 48.2 12.1 11.8 154.3 0.2 18.1 40.4 0.7 24.6 29.7 20.4 39.3 67.5 73.2 0.1 42.4 49.5 11.4 1.4 19.7 43.5 40.6 5.2 53.5 31.0 0.4 94.5 148.6 77.3 3.6 593.0 815.3 291.9 103.5 182.5 68.6 72.1 306.7 166.6 0.0 127.7 200.3 90.8 41.9 24.8 143.6 49.9 0.1 24.8 4.8 52.6 87.9 364.3 0.0 2.8 779.6 49.0 175.9 193.4 409.2 450.0 2.8 17.0 0.0 126.5 29.9 0.1 0.5 42.9 54.9 103.6 0.4 51.9 0.3 238.5 96.0 24.3 142.1 75.1 100.9 68.5 180.2 37.6 1.1 547.1 179.9 44.3 60.2 133.1 0.0 0.2 0.4 89.9 0.0 301.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.6 0.9 1.7 2.4 0.7 0.0 0.8 0.2 0.1 1.4 0.4 81.8 0.0 5.6 2.9 2.2 8.9 5.2 16.7 10.8 12.1 2.0 9.5 16.3 15.7 7.6 27.6 4.2 85.5 3.5 10.5 3.9 18.0 2.0 22.6 185.6 57.8 19.2 0.0 51.6 11.2 27.1 99.6 2.6 34.6 2.5 2.9 20.7 3.5 10.1 8.4 23.7 8.0 8.2 2.8 3.8 4.7 71.1 2.4 8.8 11.2 2.0 2.1 5.2 6.0 3.2 21.6 17.0 141.8 0.4 3.6 9.5 11.6 2.9 8.6 52.6 10.2 54.4 5.5 5.1 4.7 6.7 32.6 3.2 174.7 19.2 2.1 LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 231.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1582.4;ASC TERT1: 863.5;HSkMC: 980.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" NA NA 100000000 "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Plasma membrane" "CAB004486: AB_627870, CAB078163: AB_2665817, HPA001908: AB_1079229, HPA001909: AB_1079230" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-2)" "unprognostic (8.84e-3)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.38e-2)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-3)" "unprognostic (1.10e-3)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.85e-5)" 117.2 16.4 6.3 34.9 7.2 1.1 79.3 9.2 7.1 55.1 13.8 78.3 16.0 63.2 19.3 44.5 63.8 54.7 61.7 7.2 8.7 19.4 13.8 58.7 15.3 6.9 7.7 36.1 19.2 20.0 9.5 231.7 6.0 31.3 34.3 3.7 28.1 50.9 50.5 40.8 48.9 102.3 6.4 8.4 51.1 18.7 8.6 14.7 40.3 60.1 12.0 66.9 47.7 5.4 52.5 83.5 268.4 76.7 1582.4 863.5 405.0 374.8 373.0 147.8 87.1 249.4 58.2 18.8 168.6 180.8 87.9 127.4 51.7 99.2 112.7 0.6 52.6 0.9 71.1 91.3 248.1 16.6 8.9 980.4 52.2 177.0 138.7 262.7 261.0 0.2 0.6 55.5 182.5 22.8 0.2 17.4 109.3 96.0 15.7 13.5 226.2 9.9 237.6 137.0 17.6 50.1 98.9 0.7 95.6 459.0 21.2 43.6 486.5 179.1 70.0 168.2 95.4 21.6 0.3 12.4 148.7 12.3 177.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 7.2 9.2 7.1 7.2 8.7 6.9 7.7 6.0 6.4 8.6 5.4 81.2 35.3 21.6 32.7 8.1 31.4 46.1 44.4 35.9 3.1 7.1 17.4 57.5 27.1 21.0 36.8 4.2 101.9 0.2 1.6 1.9 59.2 5.7 32.5 58.5 80.9 1.2 0.0 69.2 23.3 69.0 187.8 8.6 78.5 2.5 53.0 26.7 19.1 18.7 1.7 50.0 2.4 18.3 10.7 20.6 6.8 120.9 4.5 33.8 106.8 6.0 2.2 1.0 35.2 2.5 44.7 2.6 62.4 11.0 59.9 0.5 12.4 14.8 0.7 72.3 73.9 102.1 17.6 36.8 17.0 16.9 72.1 2.8 74.4 3.5 25.8 LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 591.7;Proximal enterocytes: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" 86.4 38.0 60.8 75.9 56.7 126.4 55.5 45.5 56.7 46.9 48.6 93.0 131.9 43.8 32.3 45.9 46.0 56.8 40.3 56.1 61.0 55.9 76.4 68.6 76.1 56.2 63.5 48.5 59.0 25.5 33.0 81.4 59.0 30.9 92.3 26.8 44.8 33.9 23.7 44.4 168.8 51.2 52.9 74.3 96.2 23.9 67.4 74.1 34.9 27.7 78.2 53.2 37.3 50.1 214.1 441.0 124.1 111.0 182.8 196.9 218.7 267.8 257.8 274.5 198.5 134.3 225.8 98.8 214.1 417.3 154.9 332.4 58.5 204.1 239.6 71.6 31.6 47.5 124.2 235.8 173.0 110.4 134.1 176.3 69.6 234.6 66.1 170.7 188.0 59.0 81.9 30.3 389.4 72.0 127.1 163.6 63.0 189.9 109.4 70.7 67.6 123.8 332.7 187.9 19.0 45.4 159.3 160.5 134.7 233.5 255.7 128.2 331.4 160.0 233.0 189.7 162.0 79.7 115.8 75.2 170.2 96.7 197.2 21.8 31.4 35.0 30.7 33.1 20.3 11.7 15.2 20.4 27.3 10.8 12.7 19.8 67.0 34.2 42.1 20.5 21.4 32.5 60.8 56.7 45.5 56.7 56.1 61.0 56.2 63.5 59.0 52.9 67.4 50.1 54.5 41.7 27.6 17.6 41.8 41.8 21.5 26.0 51.8 66.4 82.4 43.2 1.1 55.8 30.4 73.5 10.4 7.5 69.5 225.2 17.6 65.7 89.6 27.5 31.7 54.3 86.5 21.0 16.4 76.5 59.1 50.1 119.3 46.4 52.0 37.4 64.6 115.4 83.9 26.9 16.0 101.9 28.5 127.7 73.0 591.7 51.9 71.9 35.6 24.4 94.3 22.2 164.8 11.1 4.4 111.0 116.4 39.9 32.8 24.2 292.7 72.9 57.3 23.1 65.7 65.4 53.4 2.9 5.7 62.2 28.4 6.4 63.4 19.2 97.8 31.8 LATS1 WARTS ENSG00000131023 "Large tumor suppressor kinase 1" O95835 6 149658153-149718105 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031804 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 59: Non-specific - Transcription" "HPA031804: AB_10601688" "unprognostic (4.02e-3)" "unprognostic (3.80e-3)" "unprognostic (1.28e-2)" "unprognostic (1.00e-1)" "unprognostic (4.40e-2)" "unprognostic (2.09e-1)" "unprognostic (6.15e-3)" "unprognostic (1.29e-2)" "unprognostic (9.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (5.62e-2)" "unprognostic (1.92e-1)" "unprognostic (8.43e-2)" "unprognostic (2.63e-1)" "unprognostic (2.65e-1)" 8.1 8.0 4.8 8.6 4.9 15.4 9.2 11.0 7.0 10.1 5.5 7.3 7.2 12.1 7.4 8.2 9.7 7.7 5.6 5.2 4.6 7.7 7.8 9.1 9.8 4.7 4.3 15.6 6.8 11.7 5.2 8.8 5.0 11.0 8.5 11.0 8.7 7.7 6.4 9.1 7.7 10.7 4.3 10.2 7.7 6.2 5.1 11.7 8.9 8.1 8.4 9.0 7.2 7.6 8.7 6.8 13.7 19.8 12.9 16.6 10.7 11.3 11.4 11.8 11.7 11.1 7.3 14.0 11.1 15.7 9.4 11.8 18.3 12.0 18.5 12.9 14.7 28.1 8.2 9.9 11.9 26.5 19.8 11.3 19.1 13.5 22.7 12.2 14.8 12.1 35.3 13.9 11.9 10.4 13.8 11.0 8.5 8.0 6.5 13.6 16.4 6.5 11.0 12.2 9.3 14.7 16.1 11.5 8.4 9.3 12.0 22.9 18.7 9.5 14.8 11.4 18.2 11.6 13.5 15.8 8.7 14.8 14.3 8.2 3.0 4.8 5.9 5.3 5.3 3.8 4.5 5.0 3.3 4.7 3.8 5.1 2.0 3.0 8.9 2.8 4.8 2.4 4.8 4.9 11.0 7.0 5.2 4.6 4.7 4.3 5.0 4.3 5.1 7.6 21.1 12.8 21.3 33.0 21.9 16.3 11.2 9.7 27.9 20.3 15.2 10.2 9.6 12.8 12.5 7.3 18.8 8.5 18.7 15.3 1.9 7.5 23.0 14.1 23.4 16.2 16.8 17.7 51.4 6.6 11.4 19.7 20.9 17.1 14.0 19.8 21.0 13.3 11.0 13.5 48.0 12.6 6.1 14.7 11.6 6.9 13.7 16.6 14.2 32.8 15.0 10.7 10.3 54.8 64.0 9.9 11.5 25.9 21.9 15.4 13.6 6.6 12.8 22.0 19.7 28.8 15.1 8.8 9.6 18.8 18.0 13.1 23.3 13.8 11.7 11.8 LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973036-21061586 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039191, HPA049037" Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Centriolar satellite, Cytosol" "HPA039191: AB_2676385, HPA049037: AB_2680609" "unprognostic (2.77e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.22e-3)" "unprognostic (3.38e-2)" "unprognostic (2.51e-2)" "unprognostic (1.84e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-3)" "unprognostic (4.48e-1)" "unprognostic (6.57e-3)" "unprognostic (8.03e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (1.66e-2)" "unprognostic (1.25e-1)" "unprognostic (7.97e-2)" "unprognostic (1.11e-2)" 19.8 12.2 3.9 7.3 4.3 15.1 12.4 4.8 3.7 10.1 7.7 13.1 2.9 12.2 3.0 11.5 9.7 15.1 11.5 5.3 3.3 9.9 9.8 12.4 5.3 5.4 4.6 11.0 10.2 4.3 2.3 13.9 4.5 9.8 4.3 1.3 6.1 8.8 16.7 7.7 6.2 13.1 4.1 11.2 7.8 14.6 5.1 2.4 13.5 13.3 3.3 14.2 8.9 4.7 6.8 7.4 16.0 9.7 18.4 24.1 14.6 22.1 22.8 22.5 19.2 21.1 10.0 0.0 10.5 33.8 8.8 9.6 9.5 10.1 33.1 3.8 2.5 12.4 9.4 16.0 28.6 3.4 4.2 36.0 18.1 14.9 9.9 11.3 32.0 2.8 2.3 0.5 28.9 11.7 0.4 11.6 3.8 7.0 3.5 2.9 28.5 0.0 16.3 3.1 0.3 0.0 17.4 11.3 23.9 13.9 9.8 6.4 40.6 23.8 15.9 17.7 14.1 2.9 1.7 0.0 5.7 3.8 18.6 0.1 0.5 0.5 0.4 0.4 0.9 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.9 0.4 0.2 0.0 0.0 0.1 3.9 4.3 4.8 3.7 5.3 3.3 5.4 4.6 4.5 4.1 5.1 4.7 36.6 41.7 9.9 12.1 2.8 32.9 14.7 8.5 21.6 0.4 12.5 11.0 24.3 15.7 10.5 5.5 0.0 24.8 21.0 6.5 3.9 10.1 139.4 40.3 30.4 35.1 0.0 8.2 0.6 7.3 8.9 37.2 8.6 62.1 5.1 9.8 44.6 19.6 9.9 0.0 0.6 1.9 6.1 17.9 49.3 13.7 25.4 26.0 17.8 21.5 11.0 4.9 13.4 2.0 8.8 18.6 2.8 34.6 8.9 21.7 0.6 9.5 11.6 1.0 6.6 32.3 30.0 8.8 14.5 9.9 25.3 48.0 8.1 7.9 1.5 15.2 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "dendritic cells: 143.9;NK-cells: 272.9;T-cells: 255.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in some" 6 "JURKAT: 365.7;MOLT-4: 536.9;U-698: 302.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 3.4 2.2 0.4 50.6 0.5 13.7 2.3 0.4 0.5 2.2 0.7 6.9 7.6 1.7 13.0 3.9 2.1 9.4 1.9 0.5 0.4 3.8 3.8 11.4 111.0 0.8 0.5 1.6 0.9 0.5 0.8 1.1 0.6 2.8 6.5 0.0 4.8 1.4 1.3 1.9 23.1 2.3 0.6 39.9 12.1 1.1 0.5 343.0 3.7 1.4 79.6 13.2 2.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 64.1 3.5 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 365.7 0.2 0.0 0.0 0.0 536.9 0.2 5.9 4.6 0.3 20.6 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.3 0.3 0.4 0.6 0.4 0.0 0.0 1.7 0.1 0.1 0.7 0.3 302.7 0.0 0.1 0.0 12.8 5.2 6.0 1109.8 4.9 1034.8 62.0 1123.8 1201.7 5.2 98.9 1260.7 1168.7 33.6 641.5 6.0 7.7 1682.7 1836.9 0.4 0.5 0.4 0.5 0.5 0.4 0.8 0.5 0.6 0.6 0.5 0.6 4.9 0.0 9.3 0.0 23.4 4.6 1.2 0.4 0.0 0.0 3.5 5.2 1.8 4.3 1.6 3.7 0.0 0.3 143.9 0.9 0.0 0.6 0.1 1.0 0.5 3.4 2.4 10.1 0.2 0.5 0.2 3.1 7.7 0.7 5.1 0.0 4.6 1.5 0.3 0.0 0.2 0.3 0.0 7.8 7.3 0.0 0.0 8.1 3.6 0.0 8.7 0.0 272.9 0.5 0.1 4.7 0.0 0.4 15.7 1.0 0.0 1.4 1.8 0.0 0.0 1.5 2.4 4.5 2.0 0.5 3.1 0.4 255.5 2.9 1.3 1.1 LCN1 "MGC71975, PMFA, TLC, TP, VEGP" ENSG00000160349 "Lipocalin 1" P31025 9 135521438-135526540 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Sensory transduction, Taste, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.8;seminal vesicle: 8.0" "Cell type enriched" "Detected in some" 8 "Basal prostatic cells: 8.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 3800000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.50e-3)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (3.99e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-4)" "unprognostic (1.22e-1)" "unprognostic (7.84e-2)" "unprognostic (9.47e-2)" "unprognostic (3.94e-8)" "unprognostic (2.07e-3)" "unprognostic (3.03e-2)" "unprognostic (5.83e-2)" 0.0 0.0 0.4 0.2 0.4 0.0 0.0 0.4 0.9 0.0 0.4 0.0 0.0 0.0 0.0 12.8 1.9 0.0 0.5 1.1 0.4 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.1 0.0 1.9 0.2 0.4 0.0 0.0 0.0 0.3 8.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.9 1.1 0.4 0.4 0.4 0.4 0.4 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LCTL "FLJ33279, KLG, KLPH" ENSG00000188501 "Lactase like" Q6UWM7 15 66547179-66565979 "Cancer-related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Early spermatids: 5.8;Late spermatids: 9.0" "Group enriched" "Detected in some" 5 "glioma: 1.5;melanoma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.6;hTERT-RPE1: 6.7;NTERA-2: 5.2;SuSa: 6.0;U-2 OS: 14.3;U-251 MG: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA071640 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 9: U-2 OS - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "Endoplasmic reticulum" "HPA071640: AB_2686428" "unprognostic (4.60e-2)" "unprognostic (5.46e-2)" "unprognostic (8.70e-2)" "unprognostic (1.56e-2)" "unprognostic (3.22e-3)" "unprognostic (3.53e-2)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (4.51e-3)" "unprognostic (4.44e-16)" "unprognostic (6.06e-2)" "unprognostic (3.39e-1)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" 0.1 0.1 1.4 0.2 1.5 0.4 0.1 1.2 1.5 0.1 1.0 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.3 1.3 0.1 0.1 0.0 0.2 2.1 1.4 0.1 0.1 0.0 0.1 0.0 1.8 0.1 0.0 0.3 0.1 0.0 0.7 0.5 0.1 0.0 1.5 0.1 0.1 0.3 1.6 0.0 0.1 0.0 0.0 0.0 0.1 3.0 0.3 0.2 2.8 0.2 0.1 0.1 0.7 0.7 0.0 0.0 0.3 0.3 0.4 0.4 5.6 0.2 0.5 0.6 0.0 0.0 0.1 0.2 0.1 0.7 0.9 1.4 0.0 0.2 0.3 0.3 0.0 0.3 0.0 6.7 0.0 0.2 0.3 0.3 0.1 0.1 0.2 0.4 5.2 0.4 0.1 0.2 3.1 0.3 0.0 0.3 0.3 0.2 0.1 0.3 1.6 6.0 0.4 0.5 0.2 1.4 14.3 0.5 6.4 0.1 0.2 0.2 1.9 0.6 2.7 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.1 0.1 0.1 0.0 1.4 1.5 1.2 1.5 1.3 1.3 2.1 1.4 1.8 1.5 1.6 3.0 0.0 0.0 0.0 2.9 0.7 0.4 0.6 0.0 0.0 0.6 0.1 0.1 0.3 1.5 0.1 0.0 0.0 0.1 0.6 0.2 0.0 0.1 5.8 0.2 0.3 0.2 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.3 9.0 0.6 0.1 0.0 0.0 0.0 1.4 2.1 0.5 1.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.4 0.0 0.6 0.4 1.6 2.1 0.0 0.3 0.3 0.9 0.3 0.1 0.4 LDHA ENSG00000134333 "Lactate dehydrogenase A" P00338 11 18394560-18408425 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2198.1;Basal respiratory cells: 2133.0;Extravillous trophoblasts: 2086.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015336, CAB069404" Uncertain Supported Vesicles,Cytosol NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol Vesicles "CAB015336: AB_2134947, CAB069404: " "unprognostic (8.83e-2)" "prognostic unfavorable (2.78e-5)" "unprognostic (3.81e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (4.66e-3)" "prognostic unfavorable (3.26e-8)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.08e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (8.09e-6)" "unprognostic (1.76e-2)" "prognostic unfavorable (9.69e-9)" "unprognostic (4.15e-2)" "unprognostic (1.89e-1)" "unprognostic (3.07e-1)" "unprognostic (1.05e-2)" 444.5 358.1 64.3 139.5 68.4 184.6 330.4 54.0 72.1 203.1 58.4 278.5 158.1 151.1 43.8 450.6 189.2 75.5 361.2 68.4 73.7 440.2 729.2 242.0 97.2 73.6 74.9 149.7 171.5 26.6 95.9 113.9 94.9 170.1 117.4 443.8 267.5 81.8 947.5 468.6 296.6 124.2 58.5 185.3 181.1 95.2 67.4 115.3 180.8 500.3 146.5 266.2 314.4 65.9 1261.4 730.9 28.4 415.2 599.8 399.3 400.6 1186.1 1148.5 936.9 1366.4 324.5 196.6 909.3 380.3 1110.8 727.1 979.2 716.1 1715.1 2082.2 331.3 422.6 329.6 629.4 588.5 148.9 811.2 235.8 411.1 760.3 380.3 373.7 1670.8 550.8 292.3 462.8 431.7 1127.7 319.4 674.8 509.3 182.7 413.2 849.4 432.0 298.0 768.0 1546.6 284.5 220.5 279.3 642.7 518.6 230.8 431.4 241.7 192.9 546.9 1228.3 455.3 1094.7 14.3 348.0 545.1 899.4 1767.1 415.0 434.1 98.4 147.1 79.7 93.8 165.0 105.2 70.4 122.1 99.6 202.1 54.4 78.1 81.0 47.1 91.3 169.3 68.0 140.8 237.6 64.3 68.4 54.0 72.1 68.4 73.7 73.6 74.9 94.9 58.5 67.4 65.9 421.7 73.7 201.6 21.5 220.8 2198.1 475.6 2133.0 523.0 464.2 213.6 229.5 241.8 175.8 837.3 309.0 146.0 509.8 427.2 696.1 434.3 1293.9 204.4 180.0 317.4 492.8 45.6 123.2 38.7 1532.3 2086.2 544.4 163.6 485.8 262.9 205.3 205.6 514.4 659.3 514.8 33.5 285.1 649.0 224.4 1155.1 129.6 287.7 373.9 1177.5 20.6 973.4 444.2 170.0 9.5 12.6 1771.4 590.3 205.0 376.0 546.8 1765.0 682.5 178.1 481.4 190.7 251.6 706.3 195.5 44.0 422.9 1723.2 501.7 410.9 196.2 362.1 530.8 LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lymphoid tissue: 349.2" "Cell type enhanced" "Detected in many" "Melanocytes: 33.8;Microglial cells: 145.2;T-cells: 70.3" "Cancer enhanced" "Detected in all" "melanoma: 25.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 142.6" "Lineage enriched" "Detected in many" 4 "T-cells: 142.6" "Group enriched" "Detected in many" 5 "JURKAT: 579.6;MOLT-4: 569.0;REH: 454.8" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "CAB019405: AB_823558, HPA002087: AB_1079245" "unprognostic (1.03e-3)" "unprognostic (7.36e-3)" "unprognostic (2.97e-2)" "prognostic favorable (1.37e-5)" "unprognostic (9.08e-2)" "unprognostic (5.24e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (1.77e-1)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.47e-6)" "unprognostic (1.12e-1)" "unprognostic (5.22e-2)" "unprognostic (7.88e-2)" "unprognostic (8.91e-2)" 1.0 12.7 10.7 13.8 7.6 11.6 2.0 6.1 7.9 4.2 14.3 1.5 0.7 8.0 4.8 3.2 5.1 3.9 0.2 5.7 9.9 2.5 0.3 3.3 31.3 8.9 11.2 1.1 0.1 0.3 1.0 11.0 9.4 3.7 1.4 0.5 1.0 1.0 0.1 2.8 4.1 3.9 5.9 9.8 1.5 12.3 18.2 349.2 3.0 0.1 22.8 5.5 3.0 5.5 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.2 7.2 1.8 4.7 27.1 0.0 0.0 0.1 0.0 2.5 0.2 7.9 0.0 3.7 0.3 17.6 6.9 0.0 0.0 0.0 23.6 2.9 0.4 0.4 0.0 0.7 3.5 0.0 579.6 14.2 0.0 2.6 1.0 569.0 0.0 1.7 6.3 1.4 454.8 9.1 0.2 2.4 1.3 3.0 5.2 0.0 0.5 83.8 6.7 2.4 0.2 0.0 11.9 10.3 0.0 15.3 38.3 17.0 100.9 7.8 0.0 48.4 0.3 0.2 0.0 8.2 0.0 1.6 0.6 68.3 29.9 0.1 0.9 142.6 102.2 1.9 32.9 0.3 0.5 97.7 36.8 10.7 7.6 6.1 7.9 5.7 9.9 8.9 11.2 9.4 5.9 18.2 5.5 1.4 3.2 1.9 2.0 4.4 3.3 1.4 1.0 24.5 0.1 0.4 5.0 1.6 0.0 0.7 0.0 0.0 0.1 6.2 0.0 13.7 0.0 4.2 5.8 22.3 22.0 0.0 9.2 0.2 0.0 0.2 2.1 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.2 4.1 0.3 1.4 7.9 0.6 2.0 33.8 145.2 3.5 0.6 10.3 0.5 0.6 0.1 0.0 0.0 5.4 1.8 0.0 0.5 2.3 0.3 0.0 0.6 9.0 16.1 6.6 11.3 1.3 0.4 70.3 0.0 0.9 0.4 LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 307.5;breast: 90.1" "Group enriched" "Detected in some" 44 "Extravillous trophoblasts: 124.2;Syncytiotrophoblasts: 432.2" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB010490 Approved "Secreted to blood" NA NA 17000000 19000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010490: AB_2296951" "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" 307.5 0.8 0.1 5.0 0.1 0.1 90.1 0.5 0.3 0.1 0.1 2.0 0.1 0.0 0.0 0.2 0.1 1.2 1.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 2.4 0.0 0.0 4.6 0.1 0.0 0.4 0.0 1.1 0.0 0.7 3.9 1.2 0.1 0.0 0.2 0.5 0.2 0.1 0.3 0.2 1.2 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.8 0.1 0.6 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 124.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.1 432.2 0.1 0.1 0.0 0.1 LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 130.4" "Cell type enhanced" "Detected in many" "Adipocytes: 97.7;Endothelial cells: 80.5;Fibroblasts: 94.2;Hepatocytes: 175.2;Langerhans cells: 66.6;Microglial cells: 129.3" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "K-562: 114.7;RPTEC TERT1: 52.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" NA NA 8240000 14000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" 24.3 7.2 5.2 3.9 5.1 5.0 20.6 4.9 6.5 21.5 25.0 5.9 3.9 24.6 6.7 9.2 16.1 14.7 6.9 5.3 12.3 7.8 130.4 22.5 9.5 5.2 5.7 25.0 3.0 2.9 11.7 5.3 5.2 9.0 5.1 2.5 11.9 7.3 2.1 15.1 5.6 18.7 6.3 3.2 13.7 3.9 7.7 4.7 10.4 32.1 5.7 9.1 4.8 5.2 3.3 2.0 2.6 2.9 11.5 10.6 9.0 14.2 8.1 4.8 4.5 1.5 7.6 1.4 10.1 18.0 1.3 2.7 2.2 12.3 12.7 17.2 3.7 18.8 7.9 0.3 7.0 1.4 1.6 29.7 6.8 2.9 10.8 36.2 13.9 1.4 114.7 2.2 22.5 0.9 1.4 0.4 4.2 2.0 0.2 0.4 2.2 0.8 52.3 1.4 1.6 26.3 3.5 1.5 4.0 14.9 5.0 5.0 5.3 4.9 10.0 1.1 7.8 3.0 2.2 0.5 10.2 5.3 4.8 4.5 0.8 1.2 0.5 0.6 0.4 0.2 0.4 0.4 0.7 0.1 0.3 0.5 0.4 0.4 0.7 0.5 1.0 0.7 5.2 5.1 4.9 6.5 5.3 12.3 5.2 5.7 5.2 6.3 7.7 5.2 97.7 0.0 11.3 47.0 2.6 35.3 1.9 3.3 2.2 4.0 3.1 3.3 6.6 11.5 4.2 9.2 0.0 1.6 1.6 0.5 3.9 1.5 1.1 2.0 4.4 80.5 0.0 10.3 20.9 1.1 2.6 94.2 2.6 12.8 1.3 2.6 52.5 175.2 2.0 1.7 21.8 0.8 2.0 6.3 66.6 2.3 34.5 6.1 35.6 129.3 3.4 0.4 2.1 29.1 24.5 1.7 1.9 7.5 2.4 7.5 0.7 6.4 2.6 1.0 0.0 41.1 10.3 1.1 1.2 4.1 29.5 2.6 4.7 3.3 0.8 2.1 LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1194.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4097.0;Paneth cells: 3445.9;Proximal enterocytes: 4397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 651.4;intermediate monocyte: 544.6;myeloid DC: 397.8;non-classical monocyte: 441.2;T-reg: 251.9" "Group enriched" "Detected in all" 13 "dendritic cells: 397.8;monocytes: 651.4;T-cells: 251.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 1169.3;CAPAN-2: 968.0;OE19: 1613.0;SK-MEL-30: 2329.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1900000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" 404.5 72.0 111.4 219.8 111.8 346.9 323.1 110.7 148.1 331.4 104.3 1194.1 691.9 162.3 53.8 437.8 223.1 273.0 246.2 110.3 109.4 120.0 27.3 356.1 84.5 118.6 111.9 251.4 79.9 19.8 60.6 141.2 108.6 143.1 875.4 68.3 358.6 177.4 78.6 473.1 853.4 158.8 110.4 61.9 340.7 63.5 125.2 53.0 72.3 105.6 114.1 300.8 273.5 114.0 298.6 96.5 3.3 2.5 581.2 1169.3 344.9 226.7 496.2 64.0 113.2 225.4 968.0 0.7 121.3 272.8 114.6 289.0 6.1 245.4 37.5 357.1 4.4 1.0 104.7 103.8 446.8 1.0 1.1 363.4 375.2 73.9 152.8 145.1 101.5 0.7 1.4 283.1 148.8 218.5 1.3 74.4 5.6 1613.0 271.1 0.7 11.3 22.4 604.8 434.2 7.8 22.6 529.0 0.9 2329.1 16.2 242.8 31.4 180.5 297.8 41.5 112.0 4.4 154.0 535.6 2.8 426.8 18.6 31.8 18.5 651.4 32.4 15.7 544.6 99.7 11.5 58.4 44.2 397.8 4.7 2.5 8.3 28.7 24.2 441.2 9.6 251.9 449.6 111.4 111.8 110.7 148.1 110.3 109.4 118.6 111.9 108.6 110.4 125.2 114.0 1157.4 721.1 359.8 33.3 42.0 631.3 624.1 1278.9 241.9 2.9 307.3 478.7 218.2 258.7 1463.3 119.5 0.0 766.1 38.8 4097.0 673.1 605.9 21.7 636.2 742.7 397.8 173.4 578.1 0.2 1057.8 1051.7 666.3 281.4 846.8 580.5 6.3 64.6 2.3 1137.4 1.7 0.5 1733.8 1778.1 287.8 844.6 44.4 555.7 651.2 848.4 14.0 639.1 300.1 9.2 2.0 0.3 1289.6 3445.9 384.0 77.4 708.4 4397.2 81.3 1506.5 14.7 144.7 220.2 521.0 11.5 6.6 524.8 797.6 483.8 119.5 2.9 1880.1 1139.7 LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 629.8;Paneth cells: 584.1;Proximal enterocytes: 931.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 862.9;SK-BR-3: 2270.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" NA NA 7100000000 "Cluster 32: T-cells - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000410: , HPA000554: AB_1079246" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.63e-3)" "unprognostic (1.62e-2)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (1.57e-2)" "unprognostic (4.55e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (1.58e-1)" "unprognostic (1.65e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" 192.8 218.6 51.2 75.0 91.4 48.6 109.5 95.6 62.3 188.8 159.8 210.8 312.9 121.4 45.2 114.2 155.6 240.8 311.4 46.6 81.4 103.1 68.5 182.8 52.7 145.6 88.3 155.6 79.1 107.8 134.9 147.0 116.8 114.3 92.6 10.0 498.7 154.2 20.0 54.0 260.9 80.2 104.3 76.8 315.6 70.1 89.8 48.8 102.0 20.4 25.3 125.0 119.0 152.5 499.0 255.3 7.2 11.2 157.3 181.4 147.9 55.7 49.0 371.3 725.7 107.5 862.9 2.8 372.7 33.5 361.7 200.1 53.6 203.7 11.5 1.2 319.0 33.8 206.0 481.0 387.7 0.4 31.6 305.8 111.5 197.5 12.6 83.8 9.9 68.7 3.4 1.5 87.7 62.8 151.2 6.0 13.0 163.7 170.7 100.1 209.9 4.8 155.5 352.6 235.1 267.4 52.7 2270.3 754.5 14.0 57.5 16.1 16.3 245.5 169.8 7.1 225.8 0.8 2.2 3.7 332.1 96.8 263.7 0.8 17.7 4.9 12.0 27.2 25.0 4.7 43.3 17.9 7.6 2.4 68.4 33.0 1.2 9.4 14.7 0.6 26.0 25.1 51.2 91.4 95.6 62.3 46.6 81.4 145.6 88.3 116.8 104.3 89.8 152.5 88.0 189.1 144.3 9.8 5.6 31.1 146.8 462.5 60.3 37.2 60.5 43.1 180.7 127.2 306.2 139.8 6.2 179.1 3.4 629.8 17.6 275.0 7.2 77.4 118.7 26.8 168.2 4.4 0.3 136.5 336.0 284.6 257.9 126.9 13.3 316.5 46.8 45.8 88.3 74.0 5.3 328.7 309.3 36.8 23.7 37.1 282.7 36.0 81.8 8.4 27.9 80.8 2.1 11.6 33.9 132.4 584.1 266.3 3.5 72.4 931.4 49.2 123.9 24.3 177.5 80.5 119.6 4.5 2.1 83.8 27.3 108.9 15.4 228.3 400.5 128.2 LGALS4 GAL4 ENSG00000171747 "Galectin 4" P56470 19 38801671-38812945 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "intestine: 1307.1" "Group enriched" "Detected in many" 4 "Distal enterocytes: 4349.4;Intestinal goblet cells: 3767.6;Paneth cells: 3353.0;Proximal enterocytes: 4572.2;Undifferentiated cells: 2684.6" "Group enriched" "Detected in many" 21 "colorectal cancer: 450.7;liver cancer: 133.6;pancreatic cancer: 213.7;stomach cancer: 190.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 205 "OE19: 987.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB025653, HPA031184, HPA031185, HPA031186" Enhanced Uncertain "Plasma membrane" NA NA 200000 "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB025653: , HPA031184: AB_2673776, HPA031185: AB_2673777, HPA031186: AB_2673778" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (2.57e-3)" "unprognostic (7.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (1.54e-1)" "unprognostic (7.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.69e-1)" "unprognostic (3.38e-1)" "unprognostic (9.71e-2)" "prognostic favorable (3.21e-4)" 1.6 0.5 0.3 86.1 0.4 0.5 5.5 0.5 0.6 1.4 0.2 1307.1 812.2 3.2 0.2 1.4 2.4 137.1 0.9 0.3 0.3 2.9 79.5 1.2 1.1 0.3 0.3 1.6 31.5 0.0 0.8 0.2 0.3 2.3 933.0 0.2 1.1 2.3 1.6 1.6 691.9 55.2 0.2 4.0 135.2 0.9 0.3 0.3 1.7 0.2 0.4 11.2 1.5 0.4 0.0 0.4 0.1 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 1.3 0.1 0.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 2.2 0.0 987.1 0.0 0.1 0.0 2.5 0.1 4.8 0.2 1.4 0.1 0.1 0.0 0.0 0.1 1.0 0.0 0.0 0.2 1.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.6 0.3 0.3 0.3 0.3 0.3 0.2 0.3 0.4 1.7 3.2 6.5 0.7 10.3 1.1 3.0 0.6 3.4 1.1 3.6 3.0 1.3 770.7 1.0 0.0 0.0 0.8 0.9 4349.4 0.0 267.1 0.2 1.9 1.8 1.2 649.7 0.0 0.3 103.3 0.5 0.8 310.4 5.7 49.0 0.8 1.8 69.0 0.1 1.7 0.3 3767.6 0.0 1.9 0.3 0.0 0.0 1.2 0.0 1.0 3.0 0.8 1.0 0.0 0.7 492.7 3353.0 0.4 0.7 1.8 4572.2 9.3 0.4 2.3 0.0 3.9 1.1 0.3 0.9 0.9 2.7 0.5 11.1 1.1 2684.6 42.4 LGI1 "EPITEMPIN, EPT, ETL1, IB1099" ENSG00000108231 "Leucine rich glioma inactivated 1" O95970 10 93757840-93806272 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 39.7;choroid plexus: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 242.9;Excitatory neurons: 57.1;Inhibitory neurons: 74.7;Oligodendrocyte precursor cells: 28.6" "Group enriched" "Detected in some" 7 "glioma: 1.8;testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.4;CACO-2: 2.0;NTERA-2: 6.1;SuSa: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (1.26e-1)" "unprognostic (4.68e-2)" "unprognostic (2.45e-2)" "unprognostic (1.01e-1)" "unprognostic (8.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.24e-3)" "unprognostic (1.85e-1)" "unprognostic (4.07e-3)" "unprognostic (8.71e-2)" "unprognostic (2.21e-1)" "unprognostic (5.93e-2)" "unprognostic (4.65e-1)" 0.5 1.8 26.8 0.1 31.5 0.0 0.2 23.8 39.7 0.1 44.7 4.0 0.5 0.1 0.0 4.3 0.1 1.0 0.5 29.2 22.6 0.0 2.7 0.0 0.0 29.9 24.2 0.0 0.2 0.0 7.6 0.0 32.9 0.7 2.6 0.4 0.1 0.5 5.9 0.3 1.5 0.6 23.7 0.0 1.8 0.4 26.7 0.0 0.2 3.6 0.1 0.9 0.3 25.2 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 31.5 23.8 39.7 29.2 22.6 29.9 24.2 32.9 23.7 26.7 25.2 0.2 0.0 0.0 242.9 0.0 0.3 0.4 0.0 0.0 0.5 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.4 0.0 0.0 57.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 74.7 0.0 0.0 0.0 0.4 1.6 1.5 0.0 0.0 10.3 0.0 0.1 0.0 28.6 3.9 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.5 0.6 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.2 LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748679 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1448.9;Macrophages: 346.1;Syncytiotrophoblasts: 416.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 209.2" "Lineage enriched" "Detected in all" 12 "dendritic cells: 209.2" "Cell line enhanced" "Detected in many" "RPMI-8226: 898.6;U-266/70: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favorable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" 173.7 44.4 37.6 82.2 38.6 20.6 69.7 31.7 60.8 52.6 51.2 102.5 110.4 30.8 36.8 64.5 36.6 145.8 85.3 40.0 40.3 205.9 111.1 107.3 177.0 35.6 37.3 33.0 37.9 247.0 24.9 262.1 42.4 51.9 105.9 19.7 56.4 32.2 50.4 32.7 97.6 65.0 35.9 202.2 107.0 29.8 62.8 52.8 93.2 50.4 54.9 144.7 52.1 49.4 33.2 47.5 30.8 57.4 94.3 76.0 108.4 70.3 67.0 71.7 84.2 36.9 58.6 18.2 101.5 116.5 44.3 81.5 0.0 60.8 33.7 1.6 36.2 1.2 24.4 42.8 27.7 1.0 2.7 54.2 29.1 68.4 39.4 21.3 82.1 33.7 7.4 150.9 5.2 45.2 8.9 1.2 15.1 208.2 32.1 8.4 27.1 898.6 59.2 129.1 33.6 23.2 97.9 59.4 53.0 66.8 43.9 0.6 47.2 35.3 44.8 64.5 21.8 462.5 58.0 25.0 20.0 0.2 69.1 1.9 1.6 0.1 0.8 3.1 1.6 17.0 5.1 1.3 19.3 14.5 15.2 9.0 1.6 3.7 1.0 209.2 9.7 7.0 37.6 38.6 31.7 60.8 40.0 40.3 35.6 37.3 42.4 35.9 62.8 49.4 34.9 57.7 128.0 8.8 33.9 23.1 37.5 36.0 22.2 10.6 31.2 37.6 29.8 42.9 48.1 31.3 93.8 181.8 24.5 64.2 9.8 61.3 1.3 79.4 23.5 38.3 36.5 22.7 19.2 50.6 140.2 63.8 73.4 177.7 8.8 17.6 276.3 46.4 1448.9 13.5 41.0 31.1 95.6 317.6 89.0 3.3 30.4 346.1 48.0 27.2 37.5 23.6 2.1 10.6 15.2 50.5 57.1 57.9 24.7 44.6 163.4 220.4 20.9 19.8 19.7 40.4 62.1 19.9 17.6 22.3 17.5 416.3 8.2 15.1 48.3 44.7 LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone subunit beta" P01229 19 49015980-49017091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 248 "pituitary gland: 4493.5" "Cell type enhanced" "Detected in some" "Early spermatids: 3.7;Late spermatids: 4.1;Pancreatic endocrine cells: 8.2;Syncytiotrophoblasts: 10.3" "Cancer enhanced" "Detected in many" "melanoma: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.7;HEK 293: 1.5;Hep G2: 1.4;K-562: 1.3;U-266/84: 2.0" "CAB022241, CAB022707, HPA038925" Enhanced Approved Cytosol "Secreted to blood" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "CAB022241: , CAB022707: , HPA038925: AB_2676272" "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (2.34e-3)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (5.69e-2)" "unprognostic (7.04e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (9.52e-2)" "unprognostic (4.86e-2)" 1.0 5.1 0.2 0.0 0.1 0.0 0.6 0.4 0.3 0.5 0.0 0.5 1.3 0.5 0.0 1.3 0.6 0.0 0.9 0.1 0.2 1.4 1.9 0.9 0.2 0.2 0.1 0.6 18.0 0.6 4493.5 0.0 0.2 0.9 0.0 0.0 1.1 0.0 0.5 3.1 1.5 0.0 0.0 1.2 4.5 5.0 0.1 0.0 0.8 0.0 0.0 0.3 0.6 0.3 0.1 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.9 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.3 0.3 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.7 0.4 0.4 0.0 0.6 1.2 0.6 0.5 0.0 0.6 0.0 0.5 0.0 0.0 0.9 0.6 0.0 0.1 0.1 2.0 0.3 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.4 0.3 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.5 0.0 0.0 0.1 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.0 3.7 0.3 0.0 0.2 0.0 0.0 0.0 0.9 1.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 4.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.2 1.1 1.6 0.0 0.0 10.3 0.1 0.1 0.1 0.1 LHX1 "LIM-1, LIM1" ENSG00000273706 "LIM homeobox 1" P48742 17 36936785-36944612 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "kidney: 10.7" "Cell type enriched" "Detected in some" 8 "Horizontal cells: 361.7" "Group enriched" "Detected in some" 4 "ovarian cancer: 8.1;testis cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.8;HMC-1: 1.6;WM-115: 7.0" "Region enhanced" "Detected in many" "cerebellum: 19.1" "Region enriched" "Detected in many" 4 "cerebellum: 15.7" "HPA044307, HPA073521, HPA074382" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA044307: , HPA073521: AB_2732226, HPA074382: " "unprognostic (3.86e-5)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.85e-2)" "unprognostic (1.06e-4)" "unprognostic (2.67e-2)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (4.20e-3)" "unprognostic (1.74e-5)" "unprognostic (1.33e-1)" "unprognostic (8.62e-2)" "unprognostic (3.05e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.5 0.2 0.5 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.4 2.1 0.0 0.0 42.3 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 361.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 13.0 0.0 1.6 0.0 0.0 0.2 1.1 2.3 0.0 0.0 0.4 0.3 0.0 0.2 0.0 LIF "CDF, DIA, HILDA" ENSG00000128342 "LIF interleukin 6 family cytokine" P15018 22 30240453-30246759 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.7;urinary bladder: 91.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 95.5;Club cells: 56.3;Endometrial ciliated cells: 71.7;Fibroblasts: 51.9;Glandular and luminal cells: 192.9;granulocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 88.3;hTEC/SVTERT24-B: 113.0;hTERT-RPE1: 104.4;U-138 MG: 123.9;U-251 MG: 94.5;U-87 MG: 97.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018844, CAB025985" Uncertain Supported Cytosol "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" Cytosol "CAB025985: , HPA018844: AB_1852814" "unprognostic (1.28e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (8.79e-2)" "unprognostic (4.61e-2)" "unprognostic (7.36e-3)" "unprognostic (4.18e-3)" "unprognostic (1.17e-2)" "unprognostic (1.41e-2)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (6.78e-8)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (8.99e-2)" "unprognostic (4.71e-3)" 37.9 4.3 0.6 22.4 0.7 1.6 4.7 0.6 1.7 6.8 6.6 7.5 6.7 11.7 0.6 3.1 9.8 47.7 18.4 0.9 0.8 14.2 5.0 29.9 4.3 1.2 1.3 2.3 13.4 0.4 10.4 2.7 0.9 12.0 8.0 3.0 4.9 2.1 0.8 10.7 9.3 8.3 1.1 1.5 7.8 0.6 2.6 1.3 5.4 1.0 1.7 91.0 2.4 1.1 29.0 47.9 1.3 10.6 0.0 3.9 17.1 4.1 17.2 5.1 12.1 7.7 47.3 0.0 10.1 0.2 88.3 7.3 1.1 13.1 6.9 6.8 2.1 3.7 19.7 10.9 4.5 0.1 36.7 4.3 2.5 113.0 3.3 104.4 0.0 0.2 0.8 0.1 22.6 21.5 0.6 0.1 1.8 27.0 29.5 0.9 15.9 0.0 40.7 11.0 0.2 0.6 4.9 0.4 8.8 5.0 1.0 0.5 0.3 123.9 45.3 47.3 94.5 0.0 0.2 0.1 97.4 0.1 58.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.7 0.6 1.7 0.9 0.8 1.2 1.3 0.9 1.1 2.6 1.1 0.6 22.4 44.2 0.3 0.0 3.4 14.0 95.5 0.0 0.1 40.0 10.9 0.2 10.0 56.3 5.5 0.0 0.2 2.9 3.9 0.0 39.6 0.3 71.7 16.2 3.6 0.0 0.0 0.0 3.4 0.7 51.9 0.5 192.9 67.0 0.2 0.0 0.0 1.1 0.0 0.0 3.5 10.2 0.6 3.2 0.0 0.0 3.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 40.3 3.8 0.0 0.4 15.7 5.3 1.0 15.6 0.2 0.0 17.7 30.2 0.1 0.2 1.5 2.8 0.3 5.5 0.1 7.1 20.3 LIFR CD118 ENSG00000113594 "LIF receptor subunit alpha" P42702 5 38474668-38608354 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 318.9;Astrocytes: 376.8;Endothelial cells: 279.5;Hepatic stellate cells: 809.2;Oligodendrocytes: 275.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 88.0;HHSteC: 38.7;SCLC-21H: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 260000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.00e-3)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" "prognostic favorable (1.92e-4)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (2.73e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-1)" 50.0 18.1 38.8 6.2 55.1 0.1 41.7 43.6 24.8 33.5 3.0 10.2 5.8 33.0 16.5 12.1 30.9 12.4 19.9 23.4 43.9 23.9 30.9 23.8 21.0 42.7 55.2 18.6 22.3 13.4 5.0 35.9 50.2 28.9 8.8 17.4 34.1 16.8 23.4 9.7 11.0 33.4 39.6 29.9 21.9 10.0 54.1 21.3 38.5 42.8 10.2 11.7 14.5 47.5 1.3 4.3 88.0 6.8 25.4 27.0 0.6 6.7 3.8 4.7 2.9 0.9 4.6 0.0 1.2 10.1 12.4 0.7 5.5 2.1 9.0 0.0 7.0 0.0 8.7 3.7 38.7 0.0 0.5 23.5 1.6 12.0 1.5 6.1 8.6 0.9 2.3 12.3 7.3 1.3 0.0 0.2 2.1 0.0 14.8 0.1 18.4 0.0 6.0 2.0 56.6 7.2 28.3 1.6 0.0 11.7 1.9 0.0 1.5 9.0 15.7 21.0 4.3 0.0 0.0 0.0 15.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 55.1 43.6 24.8 23.4 43.9 42.7 55.2 50.2 39.6 54.1 47.5 318.9 12.8 39.7 376.8 2.6 23.2 6.3 1.2 10.8 6.4 16.8 22.1 33.1 8.6 7.3 14.7 8.4 12.1 0.6 0.0 5.9 2.0 15.0 11.0 12.4 279.5 0.0 13.5 33.7 9.3 28.0 62.9 14.3 16.9 1.3 29.6 809.2 11.8 3.5 1.7 54.2 0.0 6.1 50.3 17.7 29.7 113.7 2.3 17.8 45.0 0.0 6.2 0.0 111.6 275.5 7.0 0.0 19.9 0.0 18.5 0.0 12.3 8.3 37.3 39.5 65.9 30.8 9.6 7.3 2.0 18.2 28.6 3.7 15.8 0.0 5.5 LIG4 ENSG00000174405 "DNA ligase 4" P49917 13 108207439-108218368 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001334, HPA057325" Approved Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Cytoplasmic bodies" "HPA001334: AB_1078689, HPA057325: AB_2732608" "unprognostic (9.93e-2)" "unprognostic (1.56e-1)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (1.40e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.21e-3)" "unprognostic (1.94e-2)" "unprognostic (3.04e-1)" "unprognostic (1.82e-1)" "unprognostic (1.50e-2)" "unprognostic (9.03e-3)" 7.2 8.3 6.3 8.6 6.5 3.9 5.6 6.1 9.0 4.0 8.7 5.7 7.2 4.4 8.5 4.2 4.5 6.8 6.7 7.1 10.2 8.2 12.0 6.9 11.0 6.8 6.6 5.8 3.8 11.3 5.2 5.8 6.8 5.6 6.6 23.1 4.6 5.2 7.1 5.3 7.0 6.6 6.1 8.3 7.8 9.8 7.1 21.8 7.7 6.5 8.3 6.9 2.3 7.9 15.5 5.8 15.3 10.2 12.4 13.3 5.4 14.9 11.2 11.2 13.3 6.9 6.7 26.0 11.9 9.8 13.7 6.3 10.2 9.9 19.2 15.4 9.8 12.3 13.8 3.6 14.8 16.6 12.5 12.3 16.3 10.8 9.6 10.7 13.5 47.0 4.4 4.7 17.4 8.3 27.7 12.1 3.9 12.6 3.6 25.1 6.0 4.2 14.6 9.7 9.6 9.9 3.3 9.0 11.7 11.7 7.7 25.4 20.1 6.6 7.2 7.5 13.5 12.4 8.7 41.7 25.4 9.4 15.2 0.6 1.6 4.8 1.1 2.5 1.6 1.6 1.2 1.2 1.4 2.2 1.2 1.7 2.2 1.9 8.3 1.0 1.8 1.0 6.3 6.5 6.1 9.0 7.1 10.2 6.8 6.6 6.8 6.1 7.1 7.9 5.6 9.6 9.5 13.4 9.2 2.7 2.8 4.9 3.4 10.7 4.9 2.8 11.6 1.5 10.0 1.8 8.4 2.3 7.3 7.9 9.8 5.3 11.6 8.3 5.7 4.3 9.6 0.4 16.6 7.5 1.0 4.2 7.7 6.0 3.8 3.6 4.6 9.8 5.8 18.5 16.1 5.3 2.0 7.5 3.9 5.1 2.8 7.4 1.8 10.3 9.3 7.3 4.1 13.6 24.9 8.9 6.3 6.0 6.2 2.5 3.5 6.3 21.9 13.6 13.1 4.6 3.8 19.1 4.4 4.0 5.7 1.8 4.1 8.7 2.9 3.7 LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 77.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 27.6;Horizontal cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 136.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Cytosol" "HPA028516: AB_10601751, HPA073571: " "unprognostic (1.45e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (4.95e-5)" "unprognostic (2.77e-2)" "unprognostic (1.40e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.63e-8)" "unprognostic (4.14e-2)" "unprognostic (7.00e-2)" "unprognostic (3.84e-2)" "unprognostic (5.79e-2)" 11.1 10.5 31.1 18.7 32.7 6.8 9.4 28.3 77.9 21.4 0.2 8.9 6.6 13.1 3.5 11.3 7.3 10.1 9.4 35.0 43.8 10.8 4.6 13.2 23.5 75.5 40.0 13.2 11.4 5.8 13.9 7.3 73.0 12.3 4.1 4.0 17.9 8.2 23.7 11.4 12.1 7.1 31.8 22.3 9.2 15.6 59.1 8.1 11.2 7.8 18.2 13.1 14.7 38.3 47.4 37.2 27.2 45.4 35.1 47.0 20.0 28.8 27.3 22.6 25.4 21.3 45.6 30.2 12.7 35.5 76.9 28.1 10.1 17.8 8.6 53.7 18.6 23.2 13.1 24.6 40.5 17.2 81.4 46.8 15.6 18.5 9.6 68.3 34.4 20.9 15.1 9.0 28.8 41.4 14.8 31.4 52.1 16.6 23.7 21.1 43.3 18.2 26.5 10.1 10.7 25.2 18.6 43.7 23.5 29.7 13.9 15.4 41.1 36.0 33.7 94.5 47.7 10.2 12.5 54.9 136.5 12.4 25.2 0.1 6.1 3.5 1.8 6.0 1.4 3.4 0.4 1.2 7.0 1.7 0.1 0.5 0.5 5.8 3.8 0.7 0.3 3.3 31.1 32.7 28.3 77.9 35.0 43.8 75.5 40.0 73.0 31.8 59.1 38.3 2.9 3.2 2.7 7.5 14.4 2.9 5.2 6.6 1.8 6.6 7.7 6.9 3.4 7.2 3.8 1.8 2.1 2.5 11.9 2.9 0.0 6.6 1.2 2.7 9.7 4.1 2.4 0.4 15.4 6.5 6.3 9.2 3.1 5.1 5.7 27.6 3.3 2.1 25.0 35.3 20.8 2.7 0.0 13.5 10.8 2.2 7.2 15.6 3.6 6.5 14.9 3.5 22.6 6.6 2.4 13.5 2.3 6.0 10.0 9.0 0.3 2.8 3.1 3.3 0.0 5.3 4.5 3.4 11.5 1.8 3.1 3.7 11.1 6.9 2.4 7.2 LMNA "CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1" ENSG00000160789 "Lamin A/C" P02545 1 156082573-156140081 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cardiomyopathy, Charcot-Marie-Tooth disease, Congenital muscular dystrophy, Disease variant, Emery-Dreifuss muscular dystrophy, Limb-girdle muscular dystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 1533.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 85.1;T-reg: 83.2" "Group enriched" "Detected in all" 8 "dendritic cells: 85.1;granulocytes: 23.9;T-cells: 83.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004022, HPA006523, HPA006660" Supported Supported "Nuclear speckles" NA NA 5700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "CAB004022: AB_2136278, HPA006523: , HPA006660: AB_1079231" "unprognostic (2.22e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-2)" "unprognostic (5.75e-2)" "unprognostic (7.43e-3)" "unprognostic (1.47e-1)" "unprognostic (5.23e-3)" "unprognostic (3.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.90e-2)" "unprognostic (5.10e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-1)" "unprognostic (3.08e-2)" "unprognostic (1.44e-2)" 280.2 174.8 17.6 64.9 27.1 58.1 231.5 24.1 20.6 221.7 33.0 183.3 72.8 271.4 14.5 256.2 173.8 92.1 221.7 15.8 23.1 120.9 93.2 188.5 18.2 30.3 25.2 178.2 81.8 21.3 76.9 53.0 26.1 125.3 38.2 4.7 176.1 42.8 190.0 364.3 136.8 78.8 21.0 84.1 160.6 61.9 30.9 15.3 147.4 23.8 22.9 168.7 217.6 41.8 518.8 269.7 26.2 72.4 119.5 238.7 169.4 607.3 379.6 221.3 146.8 68.3 311.9 2.8 338.7 417.9 94.6 515.4 31.4 227.8 70.3 188.6 50.8 175.4 168.4 130.8 124.0 25.7 412.9 133.0 92.0 154.8 134.7 120.2 207.5 0.7 82.8 21.9 205.8 193.1 1.0 67.8 32.1 202.9 706.0 1.6 195.9 137.7 128.9 105.6 33.8 114.9 414.3 154.2 427.4 56.2 230.1 74.2 727.9 241.6 233.0 389.1 393.3 39.5 10.5 4.9 449.2 24.8 760.4 23.9 8.3 0.4 2.8 2.1 2.5 2.4 17.8 7.3 85.1 0.2 0.2 0.7 2.1 3.7 0.2 0.3 83.2 14.6 17.6 27.1 24.1 20.6 15.8 23.1 30.3 25.2 26.1 21.0 30.9 41.8 353.5 262.8 350.0 16.0 179.1 610.5 1235.3 446.2 531.6 7.2 542.5 374.9 94.1 191.6 320.3 161.8 47.9 478.8 239.8 614.1 109.5 429.3 38.6 215.4 209.4 386.0 431.5 70.4 9.9 360.2 387.8 622.1 505.1 270.5 1181.8 145.5 277.7 103.1 343.0 13.5 15.1 601.2 177.0 60.6 1533.4 45.4 288.6 409.0 859.2 10.3 20.4 37.2 3.1 17.1 20.1 513.0 384.1 287.3 331.3 340.6 262.6 125.0 170.5 17.8 203.8 1028.4 766.8 107.4 42.2 404.1 602.4 680.9 472.3 111.6 513.8 942.6 LMO1 "RBTN1, RHOM1, TTG1" ENSG00000166407 "LIM domain only 1" P25800 11 8224309-8268716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8;skeletal muscle: 29.3;tongue: 12.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.5;Distal tubular cells: 27.4;Early spermatids: 60.7;Horizontal cells: 40.4" "Cancer enriched" "Detected in many" 6 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 33.8;SCLC-21H: 12.5;SH-SY5Y: 38.5;SiHa: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.74e-3)" "unprognostic (1.45e-1)" "unprognostic (4.75e-6)" "unprognostic (9.34e-2)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (7.06e-3)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (9.05e-2)" "unprognostic (4.36e-12)" "unprognostic (1.76e-2)" "unprognostic (8.88e-2)" "unprognostic (2.58e-2)" "unprognostic (3.13e-2)" 0.1 1.2 2.4 0.1 2.3 0.0 0.3 4.1 3.4 0.0 1.1 0.2 0.2 0.1 1.6 0.3 0.1 0.0 1.1 3.2 3.2 3.5 0.0 0.0 0.0 5.3 9.8 0.1 0.8 0.0 2.3 0.1 5.2 0.1 0.0 2.0 0.3 0.0 29.3 7.3 0.0 0.2 1.9 0.5 0.7 2.2 5.3 0.0 0.1 12.4 0.0 0.3 0.1 2.4 0.1 0.9 1.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.1 0.1 0.5 0.0 0.0 0.0 1.5 0.0 33.8 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.3 0.0 4.3 0.0 0.0 0.0 0.6 1.4 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.5 38.5 7.9 4.4 0.2 1.5 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.1 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.3 4.1 3.4 3.2 3.2 5.3 9.8 5.2 1.9 5.3 2.4 0.1 0.0 0.0 3.3 0.0 18.5 0.1 0.3 1.8 7.1 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 27.4 0.1 60.7 0.1 0.1 0.4 0.0 0.0 1.1 1.2 8.4 0.1 0.0 0.5 1.3 0.2 0.0 0.0 0.2 40.4 0.6 0.0 0.0 0.0 0.4 6.8 0.0 0.2 0.0 11.2 0.0 0.5 0.0 3.0 0.3 2.0 1.1 0.4 0.1 0.1 0.0 0.2 2.3 4.0 0.0 0.5 0.7 0.6 1.3 0.3 3.4 0.3 0.0 0.0 0.0 0.0 LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.2;Endothelial cells: 144.6;Erythroid cells: 103.7;Hepatic stellate cells: 167.4;Kupffer cells: 65.0;Microglial cells: 64.6" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cell line enhanced" "Detected in some" "HEL: 71.8;HL-60: 72.7;K-562: 60.9;NB-4: 27.3;THP-1: 81.6;U-937: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" 15.0 5.9 14.9 11.4 13.0 27.7 12.5 14.2 16.6 8.4 13.4 5.0 4.6 6.5 0.7 6.8 8.3 5.4 4.4 14.7 16.0 13.1 2.3 18.2 19.4 19.9 16.3 3.5 2.6 2.3 8.6 6.5 18.5 5.7 1.5 0.6 5.3 2.4 23.4 4.9 6.6 4.8 18.7 19.0 3.9 1.7 19.0 1.8 12.3 4.6 8.4 5.8 7.3 13.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 2.2 1.3 12.8 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 71.8 0.0 0.0 0.3 72.7 18.5 0.0 0.0 0.0 0.0 0.0 10.2 0.0 60.9 0.0 0.0 0.3 5.1 27.3 0.9 0.0 0.0 15.3 0.8 0.2 0.0 0.8 4.3 0.0 0.3 0.5 0.1 0.2 0.0 81.6 0.9 0.0 0.2 1.7 0.0 0.0 0.2 0.6 4.7 29.2 0.3 0.6 0.5 1.5 0.0 1.4 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 1.7 0.1 0.0 0.2 14.9 13.0 14.2 16.6 14.7 16.0 19.9 16.3 18.5 18.7 19.0 13.3 109.2 3.2 7.1 8.5 6.6 8.4 7.9 8.0 0.6 1.6 2.8 9.5 2.8 8.6 1.7 5.5 2.1 0.4 1.0 0.8 0.0 3.0 0.5 40.5 11.0 144.6 0.0 103.7 1.3 2.0 3.2 9.8 0.0 39.6 7.6 0.9 167.4 1.7 39.1 0.0 3.8 0.2 2.0 65.0 56.8 1.2 4.1 54.1 10.6 64.6 47.5 1.1 4.1 5.0 1.0 1.0 1.9 0.0 3.0 5.4 0.0 8.8 5.0 2.6 0.0 17.3 3.6 0.3 7.9 0.8 6.0 21.5 1.9 12.4 0.5 25.1 LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 566.5;Late spermatids: 1737.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 97.0;EFO-21: 115.2;U-698: 200.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 2700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Focal adhesion sites, Cytosol" "HPA011133: AB_1853247, HPA017342: AB_1853249" "unprognostic (1.50e-1)" "unprognostic (4.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.86e-1)" "unprognostic (4.05e-1)" "unprognostic (2.43e-3)" "unprognostic (7.97e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (3.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.57e-3)" "unprognostic (2.25e-2)" "unprognostic (6.86e-2)" "unprognostic (2.82e-3)" "unprognostic (1.48e-1)" 29.3 10.8 6.7 28.4 8.9 9.9 18.8 9.1 9.7 27.5 27.3 73.3 13.8 61.9 11.8 49.4 32.2 21.3 16.7 6.1 11.2 11.5 12.1 19.1 17.2 15.6 7.9 14.7 8.8 9.9 2.9 11.5 12.6 39.0 31.7 2.4 12.0 53.1 12.4 12.0 23.0 81.3 6.6 10.8 32.7 18.6 13.8 8.0 8.8 9.1 21.4 57.0 22.1 7.8 25.6 23.3 16.7 11.3 35.3 36.0 17.9 16.0 20.9 11.8 7.8 42.2 12.1 97.0 115.2 37.3 14.7 10.7 5.2 11.0 29.5 10.7 5.7 4.6 18.4 11.1 15.0 2.0 5.5 25.7 15.3 26.4 22.5 16.9 20.1 5.2 0.2 2.0 21.0 8.1 5.1 2.1 6.6 16.3 7.6 6.2 12.3 0.5 13.1 26.8 1.1 0.3 35.3 11.4 19.2 27.3 9.0 8.8 43.7 27.1 20.8 19.6 41.1 0.2 4.0 200.0 13.6 4.3 24.9 0.8 4.9 2.2 5.1 4.5 3.3 3.3 4.5 3.8 2.6 5.6 2.4 2.9 18.9 4.8 4.6 5.3 1.8 1.9 6.7 8.9 9.1 9.7 6.1 11.2 15.6 7.9 12.6 6.6 13.8 7.8 104.7 89.8 69.8 357.5 48.5 78.0 84.9 65.0 70.0 9.5 141.8 111.5 143.0 100.1 86.2 69.9 14.6 44.7 65.7 207.1 29.4 139.7 566.5 49.3 134.4 91.8 77.5 12.0 132.8 90.9 24.1 124.9 97.9 93.6 18.3 136.6 126.4 94.8 42.5 5.0 191.2 91.7 44.7 65.1 121.0 1737.1 225.3 75.8 80.0 308.2 55.8 24.8 54.6 395.6 214.9 120.2 158.1 476.9 24.6 172.5 127.5 80.2 60.9 7.1 335.2 159.2 368.2 9.8 8.0 64.2 68.2 18.6 55.3 46.8 151.3 149.3 LRIG3 "FLJ90440, KIAA3016" ENSG00000139263 "Leucine rich repeats and immunoglobulin like domains 3" Q6UXM1 12 58872149-58920504 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.8;Basal squamous epithelial cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 49.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010773 Approved Approved Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA010773: AB_1853275" "unprognostic (1.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.01e-2)" "unprognostic (3.88e-2)" "unprognostic (2.53e-1)" "unprognostic (3.46e-2)" "unprognostic (1.83e-2)" "unprognostic (1.34e-3)" "unprognostic (1.21e-1)" "unprognostic (1.92e-1)" "unprognostic (3.04e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-3)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.46e-2)" 20.8 2.6 3.5 6.7 4.3 0.1 18.8 2.6 3.3 21.0 11.2 18.6 14.2 12.5 10.6 22.3 14.3 17.7 5.3 3.7 3.0 10.3 10.3 10.4 4.3 4.2 5.4 22.4 18.9 9.1 7.1 11.5 3.4 10.5 25.6 1.8 32.9 10.4 4.0 35.9 13.4 15.4 4.5 8.7 17.9 3.3 4.1 12.2 58.2 7.8 9.6 18.6 18.5 7.6 3.9 3.6 13.6 1.0 24.2 28.0 3.1 9.2 26.4 8.7 9.3 10.9 5.0 3.7 18.3 10.3 10.5 17.9 5.1 23.3 6.3 28.1 17.8 0.9 6.3 5.4 4.7 1.6 0.4 27.9 49.8 9.3 19.8 16.9 24.1 4.2 0.2 4.5 5.8 1.8 4.5 0.1 14.4 4.6 5.5 0.0 11.5 9.2 6.7 19.8 13.8 0.0 8.1 5.0 8.6 19.0 9.3 0.2 10.4 11.8 8.1 7.1 12.2 1.9 0.0 0.0 2.5 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 4.3 2.6 3.3 3.7 3.0 4.2 5.4 3.4 4.5 4.1 7.6 17.1 16.0 24.6 17.9 0.1 22.4 8.2 42.8 44.9 3.8 6.3 10.3 3.7 34.3 23.0 1.8 0.0 0.8 0.5 24.5 0.0 11.8 0.3 8.2 37.0 16.2 11.5 0.0 1.8 18.1 0.5 19.6 23.4 4.6 0.0 0.1 12.1 7.3 2.6 3.3 6.0 11.4 16.2 0.3 8.2 1.8 27.1 0.4 3.6 9.4 0.0 3.4 0.0 3.5 22.4 7.4 15.6 29.0 1.8 4.4 8.7 4.9 14.1 0.2 6.6 10.6 11.3 0.5 2.0 25.3 22.4 0.3 1.0 15.0 31.5 4.7 LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2119.8;Excitatory neurons: 3755.5;Inhibitory neurons: 2917.8;Oligodendrocyte precursor cells: 5568.9;Oligodendrocytes: 1203.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8;glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.5;HEK 293: 1.7;U-138 MG: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 370000 "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" 3.1 1.4 18.6 0.0 22.5 0.0 1.6 7.2 18.7 0.3 0.0 0.3 0.0 0.0 2.2 0.0 0.3 0.1 0.3 21.5 8.7 0.4 0.2 0.1 0.0 6.8 9.4 0.6 0.1 0.1 1.9 0.0 8.2 0.9 0.0 2.6 0.6 1.0 4.4 0.4 0.1 0.0 3.3 0.0 0.4 0.3 11.5 0.2 5.6 3.5 0.0 0.1 0.9 19.8 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.2 1.7 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.6 22.5 7.2 18.7 21.5 8.7 6.8 9.4 8.2 3.3 11.5 19.8 1.4 0.0 0.0 2119.8 0.0 0.3 0.5 0.0 3.4 14.9 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.1 1.7 0.2 0.0 0.0 3755.5 0.0 0.0 9.1 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.0 2917.8 0.0 0.0 0.0 0.5 5.4 1.2 0.1 0.0 142.4 0.0 2.4 0.0 5568.9 1203.1 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 0.8 0.0 1.1 0.4 0.2 0.3 0.2 0.3 0.0 0.1 0.2 0.0 0.8 LRP6 ADCAD2 ENSG00000070018 "LDL receptor related protein 6" O75581 12 12116025-12267044 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 96.6;Oligodendrocyte precursor cells: 108.0;Oligodendrocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004490, HPA029925" Enhanced NA NA 390000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 68: Oligodendrocytes - Mixed function" "CAB004490: AB_627894, HPA029925: AB_10601768" "unprognostic (1.80e-1)" "unprognostic (3.72e-1)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (6.11e-2)" "unprognostic (1.07e-1)" "unprognostic (4.56e-2)" "unprognostic (1.37e-2)" "unprognostic (3.35e-2)" "unprognostic (6.98e-2)" "unprognostic (1.82e-1)" "unprognostic (5.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.44e-2)" "unprognostic (3.16e-1)" "unprognostic (1.23e-2)" "unprognostic (2.47e-1)" 3.7 2.2 2.0 1.2 3.9 0.2 4.5 2.5 2.0 6.6 13.5 4.6 2.8 6.5 1.9 2.0 4.4 2.8 3.3 2.0 2.8 4.4 7.9 4.6 0.8 2.2 2.7 5.4 4.9 6.2 2.6 8.3 1.7 3.4 2.8 2.8 6.8 3.2 4.5 3.4 2.7 4.1 1.8 0.9 3.4 2.1 2.8 1.2 4.5 4.6 1.0 3.4 5.3 2.9 3.9 13.3 9.9 5.3 6.1 4.0 7.8 5.8 5.4 4.6 5.3 6.5 3.6 0.0 2.8 5.6 3.8 3.7 14.6 3.7 8.7 0.0 3.9 4.1 4.9 3.2 2.1 5.7 2.8 3.2 2.0 6.9 5.4 5.1 4.8 4.1 5.0 0.0 3.0 3.2 4.2 1.1 14.4 2.2 1.7 5.3 9.2 1.0 6.8 7.6 2.0 5.6 7.4 2.5 6.0 11.5 2.0 3.7 6.9 3.6 13.2 2.6 4.9 0.0 0.0 1.9 2.9 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 3.9 2.5 2.0 2.0 2.8 2.2 2.7 1.7 1.8 2.8 2.9 21.6 41.7 49.5 96.6 1.0 15.4 8.6 11.9 9.6 28.2 20.1 19.0 15.4 11.5 16.6 14.7 22.9 3.7 0.5 20.4 1.9 9.0 1.0 18.0 39.0 25.9 10.8 0.4 58.2 13.7 3.2 24.0 25.5 29.1 0.0 32.8 22.1 46.7 2.3 6.7 58.0 12.9 10.2 2.4 6.0 5.1 30.4 1.7 14.2 35.6 0.6 19.9 1.0 108.0 97.0 11.3 20.5 38.7 1.6 14.7 15.1 5.2 6.0 29.0 0.0 21.5 17.3 21.5 26.4 11.0 13.8 3.4 1.9 23.7 14.4 8.1 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 502.2;Excitatory neurons: 92.0;monocytes: 133.1;Oligodendrocyte precursor cells: 256.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cell line enhanced" "Detected in some" "A549: 4.6;ASC TERT1: 5.6;BJ hTERT+: 3.2;RPTEC TERT1: 7.8;T-47d: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 4.8 3.1 1.1 10.1 1.9 9.0 2.6 0.9 2.1 5.1 1.2 4.3 0.6 4.8 1.9 7.0 4.1 6.2 3.9 1.3 1.1 10.9 5.6 52.4 6.8 1.7 1.1 5.4 3.6 8.4 2.1 1.2 1.4 2.6 1.8 1.5 3.5 2.0 5.5 2.1 3.6 4.0 1.1 10.8 2.1 0.8 1.2 2.5 2.9 7.9 5.4 4.5 5.5 1.9 0.0 4.6 0.0 0.0 2.3 5.6 0.0 1.3 3.2 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.4 0.0 2.1 0.4 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.3 0.0 0.5 2.7 0.1 3.1 1.5 1.0 0.4 0.5 0.6 0.4 0.0 0.0 0.0 1.3 0.0 1.7 0.0 7.2 2.2 0.0 5.2 0.0 1.8 0.0 0.0 2.1 1.7 0.0 0.0 58.2 0.0 6.9 0.3 0.0 1.3 1.1 1.9 0.9 2.1 1.3 1.1 1.7 1.1 1.4 1.1 1.2 1.9 7.4 32.1 502.2 17.3 29.9 2.4 1.8 0.4 2.8 8.6 1.3 1.4 7.8 5.7 17.3 27.6 0.0 0.0 1.9 0.0 1.9 1.3 0.5 0.4 2.6 7.0 0.0 2.1 92.0 2.7 0.1 16.1 0.5 0.4 13.9 2.7 13.2 8.2 4.6 47.1 28.0 0.0 0.0 55.8 8.7 1.2 19.0 52.2 12.4 73.1 133.1 8.6 3.1 256.9 3.1 0.8 1.1 12.0 2.8 0.6 0.0 22.5 3.4 1.0 0.0 22.5 4.8 0.3 1.0 12.6 3.1 0.4 3.4 11.2 0.0 0.7 LTA "LT, TNFB, TNFSF1" ENSG00000226979 "Lymphotoxin alpha" P01374 6 31572054-31574324 "Cancer-related genes, Disease related genes, FDA approved drug targets, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 1.9;lymphoid tissue: 5.6;testis: 4.2" "Group enriched" "Detected in some" 4 "B-cells: 13.7;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.2;MOLT-4: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA007729 Uncertain "Secreted to blood" NA NA 8150 "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA007729: AB_1852906" "unprognostic (3.76e-2)" "unprognostic (1.48e-2)" "unprognostic (1.36e-3)" "unprognostic (8.99e-5)" "unprognostic (3.22e-1)" "unprognostic (5.13e-3)" "unprognostic (2.07e-1)" "unprognostic (4.71e-2)" "unprognostic (3.10e-2)" "unprognostic (3.39e-4)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (8.72e-12)" "unprognostic (2.59e-1)" "unprognostic (5.49e-2)" "unprognostic (4.30e-2)" "unprognostic (3.03e-1)" 0.2 0.0 0.1 0.6 0.1 0.8 0.1 0.2 0.2 0.2 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.4 2.4 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.1 1.9 0.0 0.1 5.6 0.1 4.2 0.1 0.0 0.2 0.0 2.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.1 0.0 1.1 2.3 13.7 0.1 0.1 0.0 0.6 0.6 0.5 1.3 2.5 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 1.9 0.0 0.0 0.3 0.5 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.3 0.4 0.4 0.0 0.3 0.0 1.0 0.4 0.0 1.0 2.5 2.4 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.3 1.8 0.5 0.5 0.4 0.0 14.5 0.1 0.0 0.0 LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000753-96043520 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis, Lipid metabolism" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 207.2;Kupffer cells: 255.8;monocytes: 245.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Approved Nucleoplasm,Cytosol NA NA 86000000 "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB015221: , HPA008399: AB_1852816, HPA017017: AB_1852818" "prognostic favorable (9.79e-4)" "unprognostic (6.62e-2)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (4.25e-3)" "prognostic favorable (8.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (3.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" 40.2 66.9 24.6 64.5 25.5 180.4 53.6 29.4 30.6 55.6 33.8 48.2 78.1 51.1 38.4 110.1 61.7 40.3 35.5 25.0 27.8 58.1 43.9 190.8 64.1 26.3 25.4 110.5 54.9 53.3 37.4 27.4 26.0 41.1 49.6 36.9 41.2 40.9 45.0 67.8 60.5 58.3 25.7 57.8 46.6 19.9 28.1 49.2 49.4 45.0 96.4 51.9 52.7 33.0 85.2 90.4 123.5 73.4 104.2 115.1 53.8 33.7 101.8 67.5 78.1 66.6 72.0 190.0 42.0 51.9 52.8 108.3 103.4 140.1 92.3 63.3 97.0 68.5 54.3 81.8 61.8 35.7 39.4 110.1 118.4 91.9 114.5 305.3 134.9 101.1 42.9 32.5 98.7 59.2 96.7 115.0 145.8 100.7 115.5 88.9 90.5 109.7 125.7 107.7 63.9 75.5 64.2 80.4 78.3 95.1 98.7 44.7 49.0 28.3 47.6 40.2 38.2 42.8 79.4 85.4 19.1 66.2 22.3 4.4 662.9 17.7 33.4 699.2 63.4 126.1 46.6 43.4 282.3 157.5 65.0 50.5 46.0 120.4 638.8 70.4 51.2 591.5 24.6 25.5 29.4 30.6 25.0 27.8 26.3 25.4 26.0 25.7 28.1 33.0 32.8 38.5 135.0 15.3 82.8 51.9 64.8 96.6 52.3 21.4 41.8 41.1 25.3 25.8 110.2 38.6 33.3 29.3 47.9 17.6 74.3 42.9 74.3 18.4 20.8 38.2 21.6 50.5 21.3 28.0 28.2 29.7 38.2 27.3 7.6 31.5 57.8 21.7 207.2 11.8 18.5 40.4 40.7 255.8 76.6 16.4 36.7 183.3 21.4 10.3 245.5 35.5 26.8 19.6 17.5 20.8 27.1 41.0 40.1 35.4 73.2 69.3 45.0 55.6 6.6 26.7 35.4 46.9 11.6 108.0 74.9 20.8 39.1 32.9 70.4 49.7 LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 66.7;lymphoid tissue: 229.2" "Cell type enhanced" "Detected in many" "B-cells: 1087.8;dendritic cells: 183.5;Ductal cells: 280.4;Pancreatic endocrine cells: 296.2;T-cells: 554.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.6;Daudi: 127.4;HDLM-2: 82.2;HMC-1: 38.1;NB-4: 62.3;REH: 58.6;U-698: 90.8" "Not detected" "Not detected" HPA048884 Approved Approved Centrosome NA NA "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA048884: AB_2680543" "unprognostic (1.43e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "prognostic favorable (2.36e-6)" "unprognostic (2.91e-3)" "prognostic favorable (1.74e-4)" "unprognostic (1.45e-1)" "unprognostic (9.49e-3)" "unprognostic (1.42e-3)" "unprognostic (4.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (8.91e-2)" "unprognostic (4.92e-2)" "unprognostic (6.56e-3)" "unprognostic (1.99e-1)" 3.5 0.7 0.2 82.6 0.3 19.1 1.3 0.1 0.5 1.3 0.2 6.7 8.2 1.2 0.0 4.3 1.2 4.8 1.1 0.1 0.2 10.3 4.8 8.7 103.9 0.4 0.2 0.4 2.5 0.2 0.7 0.9 0.3 2.4 2.7 0.0 4.2 0.3 1.0 2.2 66.7 1.9 0.2 229.2 13.9 0.2 0.3 83.3 3.8 1.4 47.6 8.7 1.4 0.2 18.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 35.6 127.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 82.2 0.0 1.4 0.0 0.0 0.0 0.4 38.1 0.0 0.0 0.0 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 18.5 62.3 0.0 0.0 0.0 58.6 0.0 11.4 32.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.7 0.0 0.0 0.5 0.0 0.0 0.0 0.8 90.8 0.0 0.0 0.0 79.2 9.2 542.5 95.7 55.9 646.7 1027.3 924.3 419.4 14.5 1021.9 713.6 317.0 327.8 142.5 94.5 412.0 672.0 308.9 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.2 0.3 0.2 0.3 0.2 3.0 0.0 9.0 1.3 1087.8 16.3 0.5 45.7 2.2 0.7 2.9 3.7 0.5 2.8 4.7 90.1 0.0 0.9 183.5 0.9 1.9 280.4 3.5 2.2 2.0 8.4 0.0 11.2 0.9 113.1 0.3 6.3 3.1 1.5 14.0 0.1 10.8 3.5 10.1 0.0 0.9 0.4 160.7 31.0 112.1 0.2 0.6 49.8 42.7 0.0 72.3 1.8 99.9 0.0 0.3 296.2 1.6 0.0 13.6 3.0 0.0 11.6 0.9 0.2 6.6 1.3 4.3 0.4 1.2 1.2 12.4 0.3 554.0 0.3 3.6 0.3 LTBR "D12S370, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3" ENSG00000111321 "Lymphotoxin beta receptor" P36941 12 6375045-6391571 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 71.3;intermediate monocyte: 66.3;myeloid DC: 49.8;neutrophil: 45.0;non-classical monocyte: 50.1" "Group enriched" "Detected in many" 36 "dendritic cells: 49.8;granulocytes: 45.0;monocytes: 71.3" "Cell line enhanced" "Detected in many" "HHSteC: 393.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026202, HPA061617" Uncertain Supported "Golgi apparatus" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus" "CAB026202: , HPA061617: AB_2732666" "unprognostic (2.60e-2)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.23e-2)" "unprognostic (3.01e-2)" "unprognostic (3.24e-3)" "prognostic unfavorable (5.13e-4)" "unprognostic (2.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (3.66e-2)" "unprognostic (9.84e-3)" "unprognostic (6.91e-2)" "unprognostic (2.86e-1)" 67.6 64.4 13.9 36.4 14.6 11.7 60.3 14.7 15.9 65.8 18.0 72.7 48.6 68.1 20.7 81.3 49.6 48.3 37.2 13.3 15.8 55.1 135.8 66.0 14.6 19.6 17.3 46.3 78.7 54.9 26.3 48.6 18.8 61.9 34.3 1.9 61.5 44.0 26.3 75.1 51.1 62.6 17.4 44.8 67.7 13.3 18.1 11.7 57.2 23.5 18.0 65.8 65.1 17.0 98.2 130.3 0.0 41.1 245.9 183.7 89.9 67.9 153.1 98.8 101.1 62.0 148.7 0.1 39.5 145.7 0.5 112.2 0.5 140.5 38.9 0.0 0.2 58.1 53.2 36.6 393.1 4.1 94.6 270.8 255.2 70.7 197.1 102.6 91.2 0.0 55.5 0.5 115.0 93.5 0.4 29.3 1.2 155.7 74.4 0.0 6.6 0.2 149.2 112.2 0.7 0.5 63.6 122.9 143.6 5.0 20.5 105.3 58.0 34.6 39.6 129.0 72.1 0.0 0.4 0.1 14.6 35.9 129.5 5.4 71.3 0.5 0.2 66.3 0.0 0.1 0.1 0.1 49.8 0.1 0.3 0.2 45.0 1.5 50.1 11.8 0.1 27.2 13.9 14.6 14.7 15.9 13.3 15.8 19.6 17.3 18.8 17.4 18.1 17.0 47.0 60.9 68.9 2.9 3.6 39.0 87.2 46.4 72.3 4.1 33.9 35.9 15.5 45.8 60.7 31.3 0.0 31.3 12.4 78.3 9.8 52.2 0.7 23.8 48.6 49.3 52.0 15.8 0.5 99.8 43.6 50.5 89.7 45.2 29.7 30.1 50.7 66.5 48.7 0.0 0.5 57.1 34.6 77.3 34.6 5.1 52.8 50.8 23.2 14.0 43.1 9.6 11.3 5.5 1.1 69.5 82.3 39.9 3.3 110.7 136.9 30.1 42.8 1.6 26.3 33.1 42.0 1.6 0.9 78.9 61.7 37.5 4.9 28.0 63.4 97.6 LTF HLF2 ENSG00000012223 Lactotransferrin P02788 3 46435645-46485234 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Ion transport, Iron transport, Osteogenesis, Transcription, Transcription regulation, Transport" "Antibiotic, Antimicrobial, DNA-binding, Heparin-binding, Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 4255.5;salivary gland: 1162.5" "Cell type enriched" "Detected in many" 5 "Breast glandular cells: 1519.6" "Group enriched" "Detected in all" 5 "breast cancer: 239.0;endometrial cancer: 170.3;glioma: 152.6;prostate cancer: 195.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "neutrophil: 5.4;non-classical monocyte: 17.0" "Group enriched" "Detected in many" 23 "granulocytes: 5.4;monocytes: 17.0" "Group enriched" "Detected in some" 11 "RPMI-8226: 43.2;TIME: 14.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB008646, CAB016201, HPA057177, HPA059976" Enhanced "Secreted to blood" NA NA 350000000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" "CAB008646: AB_1618695, CAB016201: AB_629860, HPA057177: AB_2683361, HPA059976: AB_2684185" "unprognostic (7.24e-3)" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (3.41e-2)" "unprognostic (7.14e-3)" "unprognostic (3.45e-2)" "unprognostic (6.43e-3)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (3.43e-1)" "unprognostic (1.04e-1)" "prognostic favorable (6.30e-5)" "unprognostic (1.66e-2)" "unprognostic (3.53e-1)" "unprognostic (2.05e-1)" "unprognostic (9.09e-3)" 6.9 1.2 2.5 36.1 3.4 4255.5 333.3 4.6 4.2 658.3 2.2 2.8 1.2 4.1 157.5 23.0 4.3 7.5 5.7 3.7 6.2 105.3 3.3 29.4 8.6 4.8 21.5 0.5 18.6 6.2 7.0 3.1 12.6 154.2 2.2 0.9 1162.5 378.9 1.7 11.8 5.1 1.9 7.1 70.5 331.6 0.4 14.5 29.8 10.1 1.6 345.7 2.4 1.2 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 1.9 0.5 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.6 43.2 0.2 0.2 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 14.3 0.0 0.3 1.2 0.1 0.6 0.0 0.1 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 17.0 0.4 0.0 29.5 2.5 3.4 4.6 4.2 3.7 6.2 4.8 21.5 12.6 7.1 14.5 9.9 15.5 0.0 2.8 0.7 4.3 1.1 8.6 82.8 0.0 0.0 1519.6 198.4 1.0 2.8 298.0 71.7 0.0 0.0 6.2 0.1 0.0 1.4 1.2 0.3 0.2 8.8 0.0 3.0 0.1 0.9 0.2 2.5 56.1 2.3 1.3 0.1 5.0 0.0 0.0 0.0 0.0 0.2 14.2 0.0 0.7 1.5 5.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.1 78.6 0.0 18.6 14.9 0.0 0.0 0.3 9.9 0.2 0.1 15.4 0.1 0.1 4.0 0.1 0.1 101.7 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LYL1 bHLHa18 ENSG00000104903 "LYL1 basic helix-loop-helix family member" P12980 19 13099033-13103161 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.9;lymphoid tissue: 36.7" "Cell type enhanced" "Detected in many" "Early spermatids: 335.4;Erythroid cells: 298.9;Late spermatids: 763.9;Spermatocytes: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.4" "Group enriched" "Detected in many" 4 "B-cells: 3.7;granulocytes: 6.4;monocytes: 2.8" "Cell line enhanced" "Detected in many" "HEL: 127.7;HL-60: 90.5;HMC-1: 206.6;K-562: 102.1;NB-4: 131.9;REH: 96.5;THP-1: 86.1;U-937: 86.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA072177 Approved Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA072177: " "unprognostic (8.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.27e-2)" "unprognostic (3.29e-3)" "unprognostic (2.76e-1)" "unprognostic (3.64e-3)" "unprognostic (2.46e-1)" "unprognostic (1.05e-2)" "unprognostic (1.90e-2)" "unprognostic (5.87e-2)" "unprognostic (1.78e-3)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.18e-1)" "unprognostic (6.54e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-1)" 9.7 4.1 6.3 10.9 6.0 35.9 7.3 7.1 7.5 6.7 4.9 6.4 2.0 7.7 0.3 3.2 5.8 1.4 10.1 6.4 6.4 5.7 2.6 12.3 12.3 8.9 6.8 2.8 2.0 0.5 2.5 5.6 8.1 5.7 0.6 0.0 3.7 1.3 2.8 3.2 14.1 1.8 9.1 36.7 4.1 20.8 9.0 2.3 5.3 1.9 6.2 7.8 5.6 9.6 0.1 0.3 0.2 0.0 0.0 0.3 0.0 1.4 0.2 0.4 0.1 0.5 0.0 24.8 8.4 0.2 0.0 0.1 0.4 0.0 0.0 14.7 0.0 127.7 0.1 1.2 1.4 90.5 206.6 0.4 0.0 0.1 0.0 0.0 31.9 0.0 102.1 4.4 0.0 0.0 0.5 131.9 0.0 0.4 3.2 96.5 0.3 11.2 0.0 0.0 0.1 9.1 2.8 0.0 6.0 0.0 0.0 86.1 51.8 0.0 0.1 3.6 0.1 0.0 0.0 20.3 0.1 86.1 0.1 2.4 1.4 6.4 0.0 1.9 0.1 2.1 0.2 0.1 1.0 3.7 0.1 0.1 2.4 0.0 2.8 0.3 0.4 0.4 6.3 6.0 7.1 7.5 6.4 6.4 8.9 6.8 8.1 9.1 9.0 9.6 33.7 0.0 0.5 0.0 80.1 2.5 0.5 0.1 0.6 0.0 1.0 1.4 2.3 2.8 0.2 1.8 0.0 0.7 6.6 1.6 0.0 0.4 335.4 0.4 1.9 40.1 1.8 298.9 0.4 0.0 1.3 3.2 1.1 0.2 45.1 0.8 32.9 1.1 113.2 0.0 0.3 1.2 0.0 60.3 35.1 763.9 8.1 68.3 7.2 13.1 36.4 1.5 4.1 0.5 1.3 2.0 1.6 12.0 6.3 0.4 1.7 0.5 1.7 0.2 13.1 1.8 2.2 120.6 5.8 1.4 1.8 1.5 9.0 0.5 1.0 0.6 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 LZTR1 "BTBD29, LZTR-1" ENSG00000099949 "Leucine zipper like transcription regulator 1" Q8N653 22 20982269-20999032 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067852, HPA068772, HPA071248" Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA067852: , HPA068772: AB_2686031, HPA071248: AB_2686372" "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (2.44e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (9.81e-2)" "unprognostic (3.55e-1)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.16e-3)" "unprognostic (4.29e-2)" "unprognostic (1.65e-1)" "unprognostic (6.25e-2)" "unprognostic (1.25e-2)" 18.4 15.2 9.0 8.9 9.7 6.0 17.3 8.9 10.1 20.1 7.2 20.1 9.9 23.3 4.4 12.6 18.5 9.4 13.4 9.1 9.1 15.8 12.0 16.0 7.3 10.3 9.5 19.5 12.4 11.5 24.7 9.8 10.8 16.2 6.4 3.4 13.0 8.6 14.7 13.6 15.9 11.3 8.1 18.3 13.9 8.2 8.9 6.5 18.8 8.0 5.7 18.1 15.8 9.3 10.3 8.4 12.2 15.0 27.6 18.9 9.6 20.8 14.6 11.6 15.8 4.9 4.2 11.0 7.6 23.4 10.7 13.7 9.3 17.1 4.7 20.5 21.0 11.8 11.8 7.4 14.6 6.4 14.9 17.5 8.5 14.7 10.6 18.4 22.9 10.0 49.8 18.5 13.4 6.3 11.5 6.0 3.8 12.6 9.1 13.4 17.8 4.4 9.2 13.9 11.9 17.9 11.3 19.5 12.4 7.4 9.1 11.7 20.6 27.0 13.3 12.3 11.5 8.0 7.4 3.2 12.2 6.2 13.5 0.0 0.5 0.0 0.7 0.7 0.4 0.4 0.3 0.8 0.4 0.1 0.4 0.3 0.0 0.3 1.0 0.3 0.1 0.5 9.0 9.7 8.9 10.1 9.1 9.1 10.3 9.5 10.8 8.1 8.9 9.3 12.4 12.8 8.6 20.5 7.9 2.2 1.8 3.7 4.0 9.5 7.5 7.6 11.7 5.7 5.2 9.2 6.2 4.1 11.9 10.7 1.9 7.0 0.9 5.5 12.7 10.1 9.1 2.5 14.2 4.9 4.0 10.9 11.2 8.4 5.7 14.7 12.1 8.5 7.7 3.3 13.2 10.0 6.1 8.8 3.5 1.6 8.7 7.1 7.2 14.0 5.0 5.6 5.2 8.0 17.6 6.1 8.9 9.8 9.2 2.3 7.0 7.6 7.3 9.8 0.0 7.0 11.6 4.5 1.5 5.9 3.7 3.6 7.7 10.1 6.7 1.4 MAD2L1 "HSMAD2, MAD2" ENSG00000164109 "Mitotic arrest deficient 2 like 1" Q13257 4 120055623-120066858 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.9;lymphoid tissue: 5.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.8;Extravillous trophoblasts: 119.2;Spermatocytes: 127.8;Spermatogonia: 76.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003348 Uncertain Approved Nucleoplasm NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA003348: AB_10603014" "unprognostic (4.08e-3)" "unprognostic (7.31e-2)" "unprognostic (5.17e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (5.15e-5)" "prognostic unfavorable (2.17e-4)" "unprognostic (6.74e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "unprognostic (3.87e-3)" "prognostic unfavorable (3.07e-11)" "unprognostic (3.06e-2)" "unprognostic (4.05e-1)" "unprognostic (1.03e-1)" "unprognostic (9.70e-2)" 0.3 0.4 0.5 2.1 0.6 5.9 1.2 0.8 0.7 0.5 0.2 2.2 1.8 0.7 0.3 1.6 1.4 0.4 0.5 0.5 0.5 0.4 0.5 0.4 4.0 0.4 0.4 0.5 0.2 0.4 0.1 1.4 0.5 0.6 2.6 1.0 0.3 0.5 0.2 1.0 1.9 0.8 0.4 0.8 0.9 2.3 0.4 5.7 0.4 0.2 3.6 0.7 0.5 0.6 27.2 11.6 26.9 17.5 2.8 3.4 11.5 21.0 11.8 21.5 16.5 15.7 16.3 39.6 6.8 7.6 9.5 7.1 27.1 16.1 30.0 18.8 18.8 22.0 10.5 14.9 0.8 36.3 12.0 1.9 2.3 14.6 9.1 5.4 12.6 16.4 26.7 22.0 11.4 12.0 35.0 15.6 18.3 14.1 13.0 17.8 35.9 16.2 8.7 10.3 28.4 20.1 10.5 12.8 6.5 12.9 8.4 13.0 7.8 14.2 16.1 14.6 27.0 20.1 23.2 25.7 13.3 18.4 19.1 0.9 0.1 0.1 0.4 0.1 0.6 0.5 1.2 1.0 0.1 0.4 1.1 1.1 0.3 0.9 0.2 0.7 1.3 0.5 0.5 0.6 0.8 0.7 0.5 0.5 0.4 0.4 0.5 0.4 0.4 0.6 2.4 0.0 1.3 1.0 11.5 17.3 7.3 23.5 4.0 9.7 7.2 8.3 3.4 1.5 6.0 7.3 2.1 52.0 7.6 7.5 0.0 3.4 2.4 31.3 6.0 5.4 1.8 81.8 1.3 1.5 119.2 13.7 8.6 7.8 15.2 34.6 3.9 2.9 27.9 20.2 1.2 13.7 36.7 7.3 13.4 4.8 4.7 6.1 8.8 0.0 3.1 12.3 5.2 0.5 1.0 1.6 3.7 1.5 33.1 5.0 3.7 7.2 12.9 3.8 13.1 7.3 14.9 127.8 76.2 26.0 8.9 10.8 20.1 11.9 29.2 8.7 MAD2L2 "FANCV, MAD2B, POLZ2, REV7" ENSG00000116670 "Mitotic arrest deficient 2 like 2" Q9UI95 1 11674480-11691650 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 148.1;Late spermatids: 522.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008110, HPA024176, HPA024612" Approved Supported Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Nucleoli "CAB008110: AB_217976, HPA024176: AB_2671467, HPA024612: " "unprognostic (1.26e-2)" "unprognostic (2.55e-1)" "unprognostic (2.43e-1)" "unprognostic (3.27e-1)" "unprognostic (2.41e-1)" "unprognostic (6.84e-2)" "unprognostic (3.04e-3)" "unprognostic (1.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (4.60e-2)" "unprognostic (1.24e-1)" "unprognostic (9.09e-3)" "unprognostic (1.54e-1)" "unprognostic (9.27e-2)" "unprognostic (8.43e-2)" "unprognostic (2.36e-1)" 25.6 19.5 30.3 22.2 32.0 59.8 25.2 33.2 35.9 23.5 27.6 24.6 11.6 19.3 15.0 14.6 20.4 13.4 26.5 30.2 33.1 37.7 49.8 29.6 27.7 34.9 30.2 21.7 39.9 13.3 22.7 10.6 31.7 22.3 7.5 5.0 28.6 11.2 49.3 23.5 17.1 15.5 31.6 25.2 28.8 64.3 35.3 55.1 15.4 31.5 26.1 23.1 17.8 35.9 62.8 57.2 90.8 106.8 28.6 55.1 37.3 56.5 64.8 110.4 97.8 75.2 59.2 87.6 67.6 58.1 64.4 27.4 115.1 60.1 60.5 133.3 129.6 40.1 87.5 93.4 50.2 80.5 62.7 36.1 60.7 81.0 68.9 41.6 51.4 116.7 165.6 138.3 55.5 94.6 365.6 381.3 235.1 25.9 91.2 245.6 100.2 109.6 40.8 13.5 167.8 118.1 93.6 36.5 168.1 61.2 52.6 172.1 26.8 90.7 114.1 85.6 81.8 109.5 82.0 233.7 67.2 281.5 71.8 45.3 85.2 42.8 82.1 97.3 66.8 58.5 55.4 64.8 100.8 43.8 37.0 54.9 36.7 43.3 86.8 139.1 69.9 92.0 30.3 32.0 33.2 35.9 30.2 33.1 34.9 30.2 31.7 31.6 35.3 35.9 24.8 0.0 5.0 4.2 26.1 38.6 26.5 35.7 18.8 5.7 26.9 26.9 15.9 11.5 14.1 14.7 4.2 18.2 49.6 3.7 50.9 40.8 148.1 8.4 21.6 28.2 34.0 69.5 1.7 76.6 50.7 30.6 12.2 11.4 14.0 17.3 29.6 59.1 41.7 11.8 2.3 10.6 54.9 36.4 88.1 522.5 31.1 32.5 48.0 1.9 82.6 10.8 53.5 4.0 5.5 40.7 4.5 17.0 42.9 35.8 4.5 29.6 6.0 3.5 39.5 25.1 26.5 76.0 40.6 14.3 34.7 8.3 37.7 18.8 8.6 17.6 MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Mental retardation, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 407.6;Hofbauer cells: 273.6;Inhibitory neurons: 378.7;Kupffer cells: 394.7;Proximal enterocytes: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Group enriched" "Detected in some" 13 "Karpas-707: 207.0;RPMI-8226: 355.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" 27.8 15.4 14.6 20.7 14.5 4.0 17.3 10.3 13.5 35.0 14.2 11.4 70.3 23.5 6.0 22.6 20.1 16.7 6.8 13.7 13.0 48.2 25.7 18.8 30.9 19.0 22.6 39.2 3.2 50.8 5.3 36.1 17.6 18.4 10.7 4.7 11.8 15.4 49.6 57.8 83.0 17.8 18.7 26.0 13.0 10.0 28.7 17.9 23.1 19.8 23.9 17.7 30.5 29.8 0.0 0.0 22.4 0.0 0.8 0.0 0.5 2.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.0 0.8 0.7 0.4 0.0 7.2 8.3 0.0 0.0 0.2 1.0 0.1 14.3 0.1 6.4 0.0 0.2 0.0 0.0 0.3 2.4 207.0 1.5 0.1 0.2 0.4 13.5 0.0 0.0 0.1 6.2 355.1 0.0 1.9 0.5 0.3 0.9 0.2 0.6 8.7 0.2 0.0 4.5 0.0 6.9 0.5 0.9 0.0 0.0 0.0 0.9 0.0 1.4 38.1 0.3 0.0 1.1 1.1 8.6 0.0 3.2 2.7 0.1 0.0 0.2 0.5 0.0 0.9 0.3 0.0 4.7 0.6 14.6 14.5 10.3 13.5 13.7 13.0 19.0 22.6 17.6 18.7 28.7 29.8 40.2 9.6 14.6 24.8 10.4 88.3 3.7 30.1 51.2 9.7 8.5 33.1 8.2 57.2 7.7 3.7 0.0 1.7 71.5 18.2 11.7 1.7 1.1 8.1 114.1 42.7 3.0 8.4 5.1 0.8 3.0 73.0 12.8 6.6 22.1 73.0 407.6 63.7 273.6 0.0 378.7 8.9 16.2 394.7 57.9 9.0 149.8 127.2 44.4 122.7 2.7 78.1 40.2 67.3 20.0 4.0 9.9 115.1 48.1 33.9 288.9 146.6 3.0 2.7 13.1 42.7 40.0 1.1 2.0 107.4 141.2 4.2 122.2 28.0 10.1 5.4 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MAGEA3 "CT1.3, HIP8, HYPD, MAGE3, MGC14613" ENSG00000221867 "MAGE family member A3" P43357 X 152698767-152702347 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 8.0" "Group enriched" "Detected in some" 16 "Spermatocytes: 35.7;Spermatogonia: 54.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 264.2;K-562: 174.3;OE19: 379.3;PC-3: 155.9;SH-SY5Y: 153.4;SK-BR-3: 184.7;U-266/70: 242.7;U-266/84: 291.4" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (1.29e-1)" "unprognostic (9.34e-2)" "prognostic unfavorable (3.58e-4)" "unprognostic (4.20e-2)" "unprognostic (2.48e-1)" "unprognostic (2.53e-3)" "unprognostic (3.95e-2)" "unprognostic (2.92e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.1 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 264.2 0.4 0.0 0.0 0.0 0.1 0.0 0.1 48.8 1.2 0.0 0.0 112.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 174.3 16.6 0.0 0.0 0.1 0.3 0.0 379.3 155.9 0.3 0.0 3.1 0.0 0.0 33.6 153.4 0.0 184.7 9.1 0.1 1.8 11.1 1.0 10.1 19.0 10.2 15.2 242.7 291.4 0.1 1.1 0.0 105.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.7 54.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 MAGEA4 "CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B, MGC21336" ENSG00000147381 "MAGE family member A4" P43358 X 151912509-151925170 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 23.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 20.2;Spermatocytes: 48.7;Spermatogonia: 179.8;Syncytiotrophoblasts: 33.0" "Cancer enhanced" "Detected in many" "lung cancer: 19.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 440.0;AN3-CA: 263.1;HMC-1: 496.1;U-266/84: 836.2" "HPA021942, CAB040535" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear speckles" Cytosol "CAB040535: , HPA021942: AB_1853490" "unprognostic (7.90e-3)" "unprognostic (6.66e-3)" "unprognostic (5.39e-1)" "unprognostic (1.36e-1)" "unprognostic (5.81e-2)" "unprognostic (2.94e-2)" "unprognostic (4.10e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 440.0 0.0 0.0 263.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.1 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.1 0.0 0.0 496.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.9 0.1 0.2 4.1 0.0 0.5 132.0 0.0 2.4 105.9 836.2 0.7 0.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 4.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 48.7 179.8 0.0 0.0 33.0 0.0 0.0 0.0 0.0 MAGEA6 "CT1.6, MAGE-3b, MAGE3B, MAGE6" ENSG00000197172 "MAGE family member A6" P43360 X 152766136-152769747 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "testis: 7.1" "Group enriched" "Detected in some" 5 "Spermatocytes: 29.8;Spermatogonia: 49.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 210.0;HMC-1: 156.5;K-562: 136.8;OE19: 272.9;PC-3: 148.1;SK-BR-3: 138.3;U-266/70: 176.3;U-266/84: 119.7" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (3.09e-1)" "unprognostic (5.94e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (3.50e-2)" "unprognostic (1.74e-1)" "unprognostic (5.33e-2)" "unprognostic (8.33e-2)" "unprognostic (6.00e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 17.6 0.0 0.3 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 210.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 50.8 1.1 0.0 0.0 156.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.8 75.4 0.0 0.2 0.4 0.0 0.2 272.9 148.1 0.1 0.0 8.5 0.0 0.0 7.8 58.3 0.0 138.3 20.2 0.1 2.2 10.1 0.7 64.2 100.7 3.7 19.9 176.3 119.7 0.2 1.2 0.0 77.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 29.8 49.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MAGEB5 "CT3.3, MAGE-B5" ENSG00000188408 "MAGE family member B5" Q9BZ81 X 26216169-26218270 "Cancer-related genes, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Early spermatids: 6.0;Late spermatids: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052627 Uncertain NA NA "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA052627: AB_2681890" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEB6 "CT3.4, FLJ40242, MAGE-B6, MAGEB6A" ENSG00000176746 "MAGE family member B6" Q8N7X4 X 26192440-26195646 "Cancer-related genes, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "testis: 3.1" "Group enriched" "Detected in some" 6 "Spermatocytes: 23.5;Spermatogonia: 16.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "K-562: 4.6" "HPA041853, HPA076711" Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA041853: AB_10796785, HPA076711: " "unprognostic (2.05e-1)" "unprognostic (1.31e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEC1 "CT7, CT7.1, MAGE-C1, MGC39366" ENSG00000155495 "MAGE family member C1" O60732 X 141903894-141909374 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "testis: 7.3" "Group enriched" "Detected in some" 9 "Sertoli cells: 6.6;Spermatocytes: 17.1;Spermatogonia: 13.7" "Cancer enhanced" "Detected in many" "melanoma: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 54.3;Karpas-707: 51.6;U-2 OS: 33.8;U-2197: 65.4;U-266/70: 46.5;U-266/84: 44.4" "HPA004622, CAB015452" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB015452: AB_784404, HPA004622: AB_1853495" "unprognostic (5.63e-2)" "unprognostic (1.59e-1)" "unprognostic (1.68e-1)" "unprognostic (4.52e-2)" "unprognostic (9.96e-2)" "unprognostic (3.47e-1)" "unprognostic (8.56e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.6 0.1 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.3 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.3 0.0 0.1 3.6 0.0 0.0 0.1 0.0 0.1 33.8 65.4 0.1 46.5 44.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 17.1 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEC2 "CT10, HCA587, MAGE-C2, MAGEE1" ENSG00000046774 "MAGE family member C2" Q9UBF1 X 142202342-142205290 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 197 "testis: 19.6" "Group enriched" "Detected in some" 13 "Spermatocytes: 84.6;Spermatogonia: 91.5" "Cancer enhanced" "Detected in many" "melanoma: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 87.3;U-266/84: 99.8" HPA062230 Enhanced Supported Nucleoplasm,Cytosol Yes NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA062230: AB_2684718" "unprognostic (1.25e-1)" "unprognostic (5.68e-2)" "unprognostic (3.99e-1)" "unprognostic (2.82e-1)" "unprognostic (1.04e-1)" "unprognostic (4.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.9 3.7 0.0 0.0 0.0 0.2 5.7 0.9 11.3 0.0 0.1 99.8 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 84.6 91.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGEC3 "CT7.2, HCA2, MAGE-C3" ENSG00000165509 "MAGE family member C3" Q8TD91 X 141838316-141897832 "Cancer-related genes, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 9.8;Inhibitory neurons: 10.9;Oligodendrocytes: 36.7" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/84: 2.1" HPA052067 Approved NA NA "Cluster 70: Brain - Nervous system development" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA052067: AB_2681717" "unprognostic (3.45e-1)" "unprognostic (2.39e-1)" "unprognostic (4.01e-1)" "unprognostic (2.95e-1)" "unprognostic (2.10e-2)" "unprognostic (3.45e-2)" "unprognostic (2.35e-11)" "unprognostic (3.21e-2)" "unprognostic (4.29e-2)" 0.1 0.0 2.2 0.0 2.4 0.0 0.1 1.6 3.0 0.1 1.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.2 2.2 2.5 0.2 0.0 0.0 0.0 2.5 2.1 0.1 0.0 0.1 0.7 0.0 2.6 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 1.9 1.0 0.0 1.1 2.3 0.0 0.2 0.0 0.0 0.1 0.1 5.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 1.6 3.0 2.2 2.5 2.5 2.1 2.6 1.9 2.3 5.7 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 36.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAGED1 "DLXIN-1, NRAGE" ENSG00000179222 "MAGE family member D1" Q9Y5V3 X 51803007-51902354 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 335.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 534.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043645 Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA043645: AB_2678597" "unprognostic (5.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.29e-2)" "unprognostic (1.39e-2)" "unprognostic (3.92e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-3)" "unprognostic (2.04e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (3.15e-3)" "unprognostic (1.42e-1)" "unprognostic (6.10e-3)" "unprognostic (2.14e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.71e-3)" 32.4 125.4 69.8 37.7 73.1 16.7 38.0 34.7 71.1 99.7 99.2 40.0 32.4 57.3 102.4 26.6 64.7 58.8 70.2 70.7 108.8 43.0 71.5 40.4 29.2 57.4 66.2 62.5 80.2 76.8 157.0 116.2 76.3 71.7 39.6 37.1 85.3 89.0 46.8 29.9 32.3 77.6 62.0 35.4 54.6 56.5 84.7 49.0 73.7 39.1 31.6 45.4 35.5 49.7 21.3 76.2 238.5 205.8 184.3 330.4 128.1 281.2 357.7 152.5 240.0 157.3 71.0 29.9 53.6 534.9 54.4 15.6 215.5 99.6 113.2 31.8 83.1 20.3 0.4 205.7 140.9 75.8 35.8 312.2 35.0 128.6 29.1 267.7 184.8 77.1 31.5 57.6 310.5 194.8 87.7 25.4 187.6 69.4 154.3 88.4 154.2 4.1 156.7 37.4 60.9 340.1 0.0 80.6 41.9 232.0 145.6 18.8 185.6 66.1 166.5 234.7 31.8 37.5 59.5 60.3 257.9 6.9 175.1 1.5 4.4 3.1 21.1 6.0 18.7 17.2 13.7 18.5 13.2 19.4 17.1 20.5 1.3 16.3 6.1 55.8 21.1 14.3 69.8 73.1 34.7 71.1 70.7 108.8 57.4 66.2 76.3 62.0 84.7 49.7 12.2 76.9 34.5 85.8 17.1 11.5 20.4 48.1 12.5 33.2 41.9 27.9 53.4 32.9 63.8 35.0 8.4 335.2 17.1 18.6 29.4 47.9 2.5 35.6 73.4 24.5 57.1 13.9 97.5 49.9 171.5 69.5 34.7 54.3 17.7 60.7 39.7 62.5 114.6 45.4 138.5 74.4 54.9 9.2 6.8 10.0 43.2 6.3 24.9 42.2 4.9 39.7 13.4 101.6 55.0 33.5 13.5 57.6 72.6 20.2 15.9 33.2 48.3 12.5 13.1 28.2 50.0 5.7 5.9 12.4 8.2 185.7 11.9 169.9 25.2 18.8 MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Granulosa cells: 1684.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 120000 "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: AB_10599819, HPA031573: AB_10602181" "unprognostic (1.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.32e-1)" "unprognostic (1.69e-3)" "unprognostic (4.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.41e-3)" "unprognostic (1.39e-1)" "unprognostic (2.97e-1)" "prognostic favorable (2.88e-4)" "prognostic favorable (2.82e-4)" "unprognostic (6.34e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" "unprognostic (3.58e-1)" 81.6 125.1 102.3 52.8 97.8 31.8 162.6 104.9 112.2 174.5 111.7 106.8 54.3 134.3 101.9 67.4 149.0 94.3 142.2 95.5 121.9 141.0 57.5 85.9 48.0 125.4 118.4 255.9 75.5 148.0 195.3 177.1 128.8 208.8 53.5 74.4 103.3 169.9 88.9 60.5 62.5 140.6 108.5 60.8 77.6 63.1 110.1 68.8 149.2 91.4 46.2 111.7 95.7 108.9 34.0 61.4 373.7 111.0 171.6 229.5 66.8 137.9 243.7 106.4 187.5 62.3 84.4 47.1 361.2 279.0 88.5 45.2 106.5 104.2 76.1 84.5 87.0 100.0 68.6 122.1 145.5 25.4 71.8 310.4 43.0 109.3 55.5 223.6 209.9 55.2 24.5 55.7 207.6 94.0 57.0 41.9 134.7 59.1 72.4 37.4 132.9 68.2 148.5 25.3 56.6 149.5 54.7 62.4 330.6 437.5 263.1 42.9 185.0 90.4 141.3 135.9 39.5 35.7 32.7 34.5 132.0 66.7 477.6 178.5 31.9 132.1 119.1 80.0 91.7 59.2 98.1 112.1 41.1 63.9 97.3 112.0 11.8 108.6 140.8 25.8 108.9 127.4 102.3 97.8 104.9 112.2 95.5 121.9 125.4 118.4 128.8 108.5 110.1 108.9 77.9 44.8 42.8 17.6 37.4 42.4 96.4 198.6 43.3 69.8 123.3 97.8 60.5 44.3 175.4 77.3 29.2 231.5 36.9 11.9 246.5 107.4 3.4 42.4 96.8 116.4 58.3 10.3 12.9 53.7 133.7 151.7 20.9 57.1 102.1 1684.0 79.9 16.2 69.1 138.0 20.3 48.8 173.0 19.5 47.4 17.4 233.3 41.1 158.3 21.5 42.1 175.9 44.3 17.6 20.4 47.9 33.7 320.4 46.7 75.2 25.5 149.3 119.9 66.0 157.8 77.7 236.3 12.8 13.7 15.3 34.9 169.2 51.4 58.6 25.3 76.6 MAGI1 "AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3" ENSG00000151276 "Membrane associated guanylate kinase, WW and PDZ domain containing 1" Q96QZ7 3 65353525-66038834 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 497.7;Inhibitory neurons: 809.8;Oligodendrocyte precursor cells: 368.4;Oligodendrocytes: 532.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031851, HPA031853, HPA077002" Supported Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" Nucleoplasm "HPA031851: AB_10599289, HPA031853: AB_10602095, HPA077002: " "unprognostic (5.00e-2)" "unprognostic (9.84e-2)" "unprognostic (6.00e-3)" "unprognostic (1.73e-3)" "unprognostic (1.64e-1)" "unprognostic (2.17e-2)" "unprognostic (1.46e-3)" "unprognostic (9.46e-3)" "unprognostic (8.59e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (2.05e-3)" "prognostic favorable (4.55e-8)" "unprognostic (3.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-2)" "unprognostic (8.03e-2)" 11.3 5.0 3.7 1.3 4.8 0.0 12.5 6.3 5.9 5.5 3.9 9.7 5.0 6.2 2.0 8.0 5.8 5.3 9.0 4.7 5.3 10.2 13.4 8.8 1.1 3.7 3.8 2.7 12.6 5.9 7.7 5.3 2.6 7.1 4.2 7.0 11.6 4.9 3.8 12.5 6.4 3.1 2.7 11.9 14.7 10.3 4.1 2.0 13.4 4.1 1.8 5.4 7.2 4.9 4.1 2.2 12.3 1.3 2.4 1.7 5.5 7.0 5.9 2.6 4.0 15.1 3.5 0.0 1.0 8.3 2.1 1.2 3.4 2.4 4.1 0.0 1.9 36.1 4.3 10.2 1.5 0.0 1.1 2.7 2.0 8.9 1.8 6.8 6.0 4.7 15.6 0.0 2.8 3.1 0.0 0.0 16.6 12.2 2.1 0.0 3.5 0.9 3.1 13.5 3.9 10.8 2.7 3.3 0.1 8.0 6.4 0.0 1.6 8.2 6.0 2.1 2.9 0.0 0.0 0.0 4.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 4.8 6.3 5.9 4.7 5.3 3.7 3.8 2.6 2.7 4.1 4.9 102.8 76.9 29.8 204.7 1.3 22.3 17.7 7.9 26.2 98.3 46.5 37.5 35.6 102.9 22.5 23.9 75.0 20.2 0.5 51.0 3.9 44.3 179.1 35.8 35.5 55.5 36.5 2.7 497.7 31.8 2.4 9.6 47.4 50.8 1.3 78.4 82.5 60.9 4.8 232.2 809.8 40.3 12.2 5.0 3.6 27.0 6.5 1.8 5.4 170.5 0.6 15.2 0.0 368.4 532.1 40.3 25.4 8.6 0.2 14.7 33.2 12.2 40.3 26.4 32.9 7.0 17.5 44.7 12.3 12.7 18.8 5.1 2.7 27.1 26.3 11.9 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 7.1 2.5 2.9 11.2 2.8 10.5 6.3 4.8 3.6 7.7 4.2 5.1 3.6 5.4 4.2 12.5 5.1 5.8 5.4 3.1 4.1 6.7 6.9 7.3 21.1 3.2 2.6 5.3 4.0 5.3 4.7 4.0 3.0 11.5 5.5 8.7 5.8 3.8 8.3 9.4 7.7 4.2 3.0 11.5 4.6 8.2 4.1 15.6 5.3 2.8 23.1 7.1 9.6 3.6 11.4 16.0 16.8 5.2 3.1 6.7 9.2 19.7 12.1 15.7 12.6 13.8 13.5 27.0 10.3 24.0 11.1 12.0 10.8 7.6 20.8 17.0 6.8 9.7 9.0 21.8 4.0 20.1 11.4 4.0 12.2 11.8 10.4 6.6 3.4 7.7 15.3 42.3 9.6 3.3 4.7 9.7 6.3 4.1 7.1 14.8 11.5 19.7 88.9 2.8 2.5 4.5 11.7 6.0 9.3 12.0 5.1 12.2 5.7 22.6 9.1 7.1 20.8 38.5 54.4 16.3 10.6 15.6 9.9 0.3 0.5 0.2 0.7 0.7 0.6 1.1 1.4 0.8 0.7 2.1 1.0 0.8 0.3 0.5 0.5 1.3 0.8 0.4 2.9 2.8 4.8 3.6 3.1 4.1 3.2 2.6 3.0 3.0 4.1 3.6 35.0 22.4 19.2 24.2 67.8 33.0 32.3 4.8 26.2 14.7 13.6 11.0 14.4 10.0 7.0 11.0 85.5 6.2 53.2 11.1 3.9 16.6 12.7 10.4 17.5 31.1 6.7 0.8 61.3 8.5 6.0 15.7 13.7 24.7 31.7 28.1 10.4 11.1 11.8 55.5 42.9 8.6 8.2 21.0 96.5 8.0 10.2 55.9 12.4 34.7 79.5 26.2 20.6 52.3 11.9 16.2 21.9 7.2 42.2 46.6 8.0 30.7 5.8 18.1 19.7 16.1 12.9 40.1 35.6 25.4 24.7 9.0 55.2 5.7 10.7 38.1 MAML2 "KIAA1819, MAM3" ENSG00000184384 "Mastermind like transcriptional coactivator 2" Q8IZL2 11 95976598-96343195 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 690.5;Microglial cells: 579.9;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 311.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035223 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA035223: AB_10671101" "unprognostic (8.11e-2)" "unprognostic (2.51e-1)" "unprognostic (7.08e-2)" "unprognostic (9.07e-2)" "unprognostic (3.57e-3)" "unprognostic (3.32e-2)" "unprognostic (3.66e-2)" "unprognostic (2.33e-1)" "unprognostic (3.99e-2)" "unprognostic (8.05e-2)" "prognostic unfavorable (3.89e-4)" "unprognostic (9.11e-2)" "prognostic favorable (1.90e-4)" "unprognostic (9.76e-2)" "unprognostic (1.73e-2)" "unprognostic (1.99e-1)" "unprognostic (7.19e-2)" 10.9 2.7 5.8 6.3 5.5 3.1 14.2 17.2 3.9 10.6 6.9 6.1 3.0 5.4 1.8 5.5 8.0 7.7 4.4 7.1 10.6 9.9 2.4 9.8 8.7 9.0 9.0 7.9 5.9 5.9 4.0 12.2 7.4 7.4 6.2 6.8 11.0 5.7 2.0 7.9 4.8 6.5 7.0 10.3 4.8 2.3 7.5 13.7 6.5 4.8 7.0 8.8 6.5 6.6 10.7 2.0 17.8 4.7 18.1 20.7 3.8 12.1 17.9 7.8 8.1 1.3 22.1 2.3 27.7 28.1 4.1 9.6 3.6 11.7 10.7 52.8 1.3 1.4 3.7 4.1 10.5 0.1 0.0 30.4 1.1 13.9 8.2 14.3 4.5 0.3 6.1 3.2 14.0 0.9 0.2 2.9 1.9 5.5 3.3 3.7 3.4 12.3 11.6 14.8 0.1 1.6 4.5 1.9 5.0 5.7 1.7 0.5 19.7 13.6 3.2 4.7 7.7 2.2 0.4 3.3 6.5 2.0 25.6 0.1 0.6 0.0 0.8 0.3 1.3 0.9 1.6 2.1 0.6 1.2 3.2 2.2 2.6 2.4 0.4 0.5 0.6 1.2 5.8 5.5 17.2 3.9 7.1 10.6 9.0 9.0 7.4 7.0 7.5 6.6 43.5 16.0 8.6 690.5 35.4 19.5 21.5 12.6 19.9 44.1 28.6 43.1 5.3 18.6 16.6 12.9 91.8 15.4 21.8 31.0 11.7 19.3 1.4 61.6 49.4 24.0 6.7 2.7 81.6 0.4 26.0 41.6 20.9 52.3 1.3 44.0 9.3 0.4 18.6 0.0 36.8 7.6 4.1 19.2 21.2 3.0 8.7 29.3 12.4 579.9 26.0 21.9 16.5 1300.8 311.4 15.0 16.8 8.6 18.1 19.1 9.4 17.1 24.2 25.9 32.9 3.6 51.5 0.6 0.8 19.4 13.5 13.0 38.1 9.0 14.3 19.2 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124122 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 724.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003835, HPA051993" Supported Supported Cytosol NA NA 140000 "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB003835: AB_562312, HPA051993: AB_2681685" "unprognostic (4.39e-1)" "prognostic favorable (3.72e-4)" "unprognostic (4.24e-1)" "unprognostic (1.26e-3)" "unprognostic (2.58e-1)" "prognostic favorable (7.98e-4)" "unprognostic (2.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (7.45e-3)" "unprognostic (4.95e-2)" "unprognostic (1.32e-1)" "prognostic favorable (5.43e-5)" "unprognostic (2.91e-2)" "unprognostic (2.25e-1)" "unprognostic (4.90e-2)" 73.9 118.4 145.5 54.1 143.1 102.4 69.1 151.5 190.7 76.6 150.4 103.4 134.0 72.3 23.2 121.6 64.7 30.4 156.6 145.9 147.3 82.6 123.3 66.8 57.1 149.6 152.9 84.1 134.3 54.9 99.3 36.4 154.3 93.9 42.7 68.0 79.6 37.6 289.0 95.8 101.0 31.7 143.5 89.1 92.7 131.6 150.7 69.3 74.6 132.1 41.0 77.2 75.2 142.8 163.1 175.4 93.7 132.8 127.1 151.9 93.8 104.5 138.8 139.6 125.8 153.0 85.5 137.7 95.9 120.0 111.9 114.3 74.2 111.6 107.4 118.1 90.4 50.5 91.4 171.7 194.0 93.6 101.8 168.8 106.8 98.2 129.5 185.5 125.2 123.0 98.1 263.1 119.3 203.5 186.3 130.6 107.8 118.6 125.9 140.7 61.9 159.1 123.5 102.7 126.8 126.3 95.7 130.6 344.1 107.3 101.0 158.5 111.8 113.6 98.2 293.4 163.9 263.1 172.4 100.2 176.5 166.8 199.3 27.5 13.0 45.4 16.9 16.6 13.6 13.0 13.3 17.2 15.9 18.2 12.3 15.9 21.2 18.8 14.1 9.0 14.3 7.3 145.5 143.1 151.5 190.7 145.9 147.3 149.6 152.9 154.3 143.5 150.7 142.8 77.7 9.6 31.9 22.5 62.3 35.4 93.3 21.3 15.4 85.1 92.9 95.4 62.9 44.3 22.8 40.5 41.7 28.7 102.3 300.5 146.8 20.7 248.1 59.5 68.3 52.1 63.2 123.1 17.6 45.5 38.6 60.3 64.7 48.8 19.7 124.4 49.2 48.1 55.0 121.1 23.2 107.7 16.2 56.0 38.2 724.3 35.8 65.6 42.7 10.3 28.5 121.1 62.8 13.0 24.2 47.0 151.8 23.0 79.9 103.2 166.1 92.8 18.9 106.8 26.3 93.1 71.8 23.5 17.4 42.9 63.9 35.6 77.0 120.2 119.9 113.1 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020829-12143830 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 226.9;Inhibitory neurons: 189.3;Oligodendrocyte precursor cells: 148.3;Oligodendrocytes: 203.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.4" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "SuSa: 177.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: AB_2684197" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 11.4 13.1 27.3 10.1 30.2 3.6 14.5 18.7 44.8 12.0 8.7 12.0 10.1 12.1 17.5 18.8 11.4 10.9 15.8 32.7 28.5 16.2 21.8 11.7 11.7 30.0 21.8 12.6 11.5 19.4 13.8 15.8 30.9 14.3 13.1 15.4 10.5 12.7 24.1 15.1 10.5 13.8 19.0 11.6 11.2 11.0 25.9 15.2 16.7 28.2 14.4 14.7 13.0 30.1 31.1 26.2 33.8 17.5 18.3 23.5 21.3 20.6 27.1 23.1 21.9 15.6 10.4 12.8 16.4 32.4 15.2 20.2 29.7 28.8 34.3 22.7 33.7 14.2 14.1 29.8 21.4 13.7 20.5 19.6 27.9 27.0 28.0 23.9 21.3 17.8 15.4 7.3 29.4 11.5 16.8 12.9 19.6 33.2 12.4 20.3 37.8 8.9 31.6 19.7 6.8 19.9 23.8 12.7 20.3 177.7 16.1 10.0 19.6 11.3 17.4 15.8 24.9 14.2 16.9 9.9 21.3 10.7 16.8 0.4 2.1 1.7 2.2 1.2 1.9 2.1 1.8 1.8 1.5 2.7 1.5 2.4 10.4 2.7 3.9 1.5 2.2 1.8 27.3 30.2 18.7 44.8 32.7 28.5 30.0 21.8 30.9 19.0 25.9 30.1 13.9 9.6 19.4 71.8 27.1 41.4 36.1 12.7 66.0 15.3 20.4 16.3 22.6 7.2 18.3 14.7 8.4 12.6 17.7 19.1 25.4 12.3 7.2 16.9 16.4 12.0 12.0 14.5 226.9 14.3 10.3 19.4 42.3 27.3 1.3 20.1 11.0 20.8 11.7 18.5 189.3 13.1 20.3 19.9 14.7 8.9 11.8 15.4 12.4 68.4 24.1 11.3 14.4 148.3 203.0 16.9 9.3 12.8 26.9 37.7 11.0 25.2 8.6 10.0 13.1 19.2 20.2 7.3 9.3 56.7 39.2 25.3 20.7 15.0 13.3 41.5 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.5;THP-1: 51.0" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 57: B-cells - Immune response" Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 5.5 3.8 3.0 13.3 2.6 24.0 20.1 4.0 2.1 7.0 6.2 5.4 6.3 7.5 6.6 10.0 9.7 5.7 3.7 2.1 2.7 9.9 6.0 7.5 18.1 3.9 3.2 7.2 9.8 7.1 1.3 11.4 3.7 5.4 6.3 26.9 18.5 8.3 1.7 19.7 6.5 5.7 3.8 20.5 8.1 8.3 3.5 9.9 16.2 4.4 24.0 6.7 6.4 3.9 13.3 7.9 12.1 8.1 1.9 1.5 20.3 2.5 3.3 7.6 10.6 37.1 9.7 11.9 0.9 3.0 6.5 6.7 10.1 4.6 10.5 4.0 4.4 6.6 3.4 17.5 4.7 10.6 17.6 1.9 4.8 2.4 3.8 2.1 3.3 4.0 5.8 20.7 2.0 5.8 7.4 14.2 5.6 6.8 1.0 11.5 8.6 41.1 13.2 13.6 5.1 52.5 7.6 9.5 21.5 10.7 26.0 51.0 9.8 0.7 6.4 2.9 4.7 15.0 8.2 22.1 1.2 6.1 13.2 6.3 3.1 0.7 0.8 4.5 0.7 4.0 2.4 1.1 1.8 3.3 1.5 0.5 1.7 1.7 4.9 1.0 3.8 1.7 3.0 2.6 4.0 2.1 2.1 2.7 3.9 3.2 3.7 3.8 3.5 3.9 20.8 6.4 9.8 17.9 102.5 52.4 15.1 17.1 43.9 14.9 73.2 30.6 3.5 48.6 15.9 36.8 47.9 15.1 31.9 7.3 7.9 18.9 2.0 25.0 20.6 24.0 10.2 14.5 11.7 14.8 8.6 10.7 14.3 43.7 7.6 20.0 21.8 15.0 32.3 28.6 31.8 11.4 6.1 76.0 48.4 3.6 5.3 66.5 37.4 69.3 99.1 11.6 9.2 210.1 12.5 12.9 7.7 1.9 41.5 14.8 10.6 20.7 11.0 38.5 6.6 9.3 11.9 8.6 17.9 69.1 54.7 6.7 31.6 15.4 9.7 12.0 MAP3K13 "LZK, MEKK13" ENSG00000073803 "Mitogen-activated protein kinase kinase kinase 13" O43283 3 185282941-185489094 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016497, HPA036691, HPA036692" Uncertain Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA016497: AB_10670027, HPA036691: AB_10673661, HPA036692: AB_10670845" "unprognostic (8.95e-2)" "unprognostic (6.72e-3)" "unprognostic (9.46e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (5.16e-2)" "unprognostic (2.81e-1)" "unprognostic (2.61e-1)" "unprognostic (1.23e-2)" "unprognostic (9.04e-2)" "prognostic favorable (1.11e-4)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.70e-3)" "unprognostic (1.54e-2)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (6.64e-2)" "unprognostic (9.31e-3)" 14.7 34.0 18.5 13.0 19.8 15.8 21.0 23.2 25.8 17.0 18.5 24.6 24.3 17.9 56.8 19.7 20.2 18.1 10.4 19.7 20.4 30.9 29.6 17.5 11.7 20.7 21.7 22.2 25.9 34.6 20.7 13.1 21.1 19.7 26.2 36.2 26.2 14.9 4.7 14.0 25.0 17.0 21.2 13.1 23.9 18.8 21.5 11.1 25.7 6.8 15.0 23.2 15.8 23.5 73.9 14.5 27.4 0.7 24.4 29.9 16.1 16.5 11.2 26.2 31.5 27.9 27.0 0.6 55.1 30.4 43.7 41.1 0.8 38.4 46.5 82.1 36.8 0.3 18.9 23.3 26.5 39.2 20.1 27.2 32.8 22.6 28.1 27.1 29.6 0.7 0.9 57.5 23.8 23.0 4.6 18.2 31.5 56.5 33.4 0.6 32.8 40.5 46.9 18.8 44.7 29.8 28.0 41.5 59.9 29.8 62.8 21.5 19.7 21.5 27.8 39.4 36.5 29.3 40.8 24.4 31.4 19.5 36.1 14.0 21.6 9.4 16.6 22.1 25.7 42.8 19.6 21.0 37.4 34.9 27.2 26.6 35.9 20.8 15.9 16.4 8.6 12.4 18.5 19.8 23.2 25.8 19.7 20.4 20.7 21.7 21.1 21.2 21.5 23.5 69.5 54.5 82.7 80.0 41.8 141.6 219.1 196.7 100.7 117.9 144.0 115.1 25.2 144.4 131.6 79.1 91.8 139.5 22.9 96.1 287.6 106.6 134.8 76.5 50.7 65.9 106.4 43.8 170.7 127.5 38.9 49.0 72.4 73.1 29.8 96.6 93.5 99.4 64.9 45.4 184.5 130.9 138.4 53.2 193.0 213.0 43.2 52.7 85.4 28.1 283.9 137.5 22.6 102.1 89.8 137.5 95.1 54.2 40.6 322.2 111.6 283.9 125.7 88.8 46.0 38.5 62.7 119.5 39.1 94.6 145.6 203.4 32.2 50.0 109.3 279.4 MAP3K3 "MAPKKK3, MEKK3" ENSG00000198909 "Mitogen-activated protein kinase kinase kinase 3" Q99759 17 63622415-63696305 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007764, HPA035410, HPA035411" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "CAB007764: AB_562314, HPA035410: AB_2674614, HPA035411: AB_2674615" "unprognostic (9.65e-3)" "unprognostic (1.33e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (4.12e-2)" "unprognostic (1.03e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.46e-3)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (2.79e-2)" "unprognostic (4.68e-2)" "unprognostic (1.09e-1)" "unprognostic (3.08e-2)" 30.1 12.3 11.3 23.7 12.4 31.5 23.6 13.9 12.3 21.6 13.6 28.8 8.7 23.8 6.5 17.7 24.2 21.8 40.9 10.5 12.1 22.9 13.9 28.7 22.3 14.9 12.7 24.0 12.9 15.2 13.8 22.9 13.2 22.2 8.5 6.9 15.1 18.4 23.7 19.3 18.7 22.0 13.1 34.5 18.7 17.2 12.9 15.1 18.0 30.3 14.5 23.4 19.1 13.6 22.6 16.3 20.4 20.1 37.7 30.2 9.4 22.0 24.4 27.0 21.2 7.8 4.5 24.2 15.0 43.2 18.7 8.3 13.4 15.5 16.9 21.7 29.3 19.6 22.6 11.0 19.5 15.6 20.1 22.3 10.4 33.6 17.1 16.3 65.7 17.4 12.2 31.1 21.4 15.9 27.3 15.9 12.5 4.5 16.8 14.3 53.0 15.6 9.4 10.3 10.6 25.3 14.6 17.1 17.9 24.9 17.3 14.8 60.5 67.8 17.8 37.3 26.9 30.3 33.6 8.9 14.4 12.0 18.0 15.0 11.4 15.3 2.8 11.8 3.0 2.0 3.4 2.8 4.9 2.4 3.3 3.2 25.1 1.9 12.5 1.9 2.9 3.5 11.3 12.4 13.9 12.3 10.5 12.1 14.9 12.7 13.2 13.1 12.9 13.6 31.6 19.2 14.5 23.5 11.0 7.8 5.4 3.9 5.7 15.8 9.5 8.9 10.3 12.8 5.1 16.5 14.6 3.2 25.8 3.3 9.8 4.5 8.3 10.0 12.3 33.0 4.2 2.1 39.8 8.1 3.3 13.6 3.1 9.3 3.8 7.1 48.2 10.1 16.3 18.5 34.2 3.9 2.0 47.1 13.0 6.4 14.9 35.1 23.2 54.4 42.7 8.8 24.7 31.2 36.1 5.2 1.9 13.2 8.3 8.2 3.7 2.4 5.4 14.0 19.7 21.9 12.9 23.9 17.8 6.1 11.2 1.4 15.6 6.2 4.5 3.8 MAP3K4 "KIAA0213, MAPKKK4, MEKK4, MTK1" ENSG00000085511 "Mitogen-activated protein kinase kinase kinase 4" Q9Y6R4 6 160991727-161117385 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 31.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007625 Uncertain Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Cytosol "HPA007625: AB_1853770" "unprognostic (3.05e-3)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-1)" "unprognostic (7.65e-2)" "unprognostic (1.35e-3)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-3)" "unprognostic (2.09e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.93e-1)" "unprognostic (6.84e-2)" 4.9 3.9 5.1 6.4 4.4 5.8 6.0 9.4 7.7 7.8 0.0 6.0 5.3 9.3 3.6 8.5 7.2 4.5 5.5 6.4 4.8 5.0 4.5 6.2 7.3 2.7 2.0 8.6 6.4 8.0 3.9 7.1 3.6 7.3 5.3 4.1 7.3 6.3 11.1 8.5 5.5 7.6 2.7 6.3 5.8 7.5 3.1 9.6 5.5 10.2 9.8 7.1 6.7 5.6 8.1 9.0 16.8 14.7 9.9 11.9 11.1 9.0 7.9 10.2 10.7 12.6 5.8 16.7 6.4 23.2 14.6 19.7 17.4 18.0 12.4 12.4 14.3 21.8 8.5 12.9 7.9 22.9 10.1 7.6 20.5 10.7 9.6 15.8 13.5 12.4 56.1 18.8 11.0 8.3 15.6 11.9 10.3 5.8 13.8 16.9 15.6 13.3 9.0 5.8 9.7 8.5 17.0 17.8 1.5 14.7 7.4 27.6 13.0 12.4 15.9 11.7 43.3 10.8 9.3 15.3 14.6 23.2 13.2 31.5 4.0 2.7 5.2 3.2 9.3 6.7 7.5 4.8 4.9 9.1 5.2 5.2 0.2 4.1 1.9 6.1 5.7 3.0 5.1 4.4 9.4 7.7 6.4 4.8 2.7 2.0 3.6 2.7 3.1 5.6 19.9 19.2 12.2 32.7 20.8 9.8 10.5 9.7 30.7 18.5 13.3 16.8 20.9 10.0 14.9 14.7 22.9 20.6 17.0 7.1 3.9 9.7 5.5 35.3 55.4 14.5 15.4 12.8 66.1 7.5 11.5 16.1 15.8 39.4 3.8 35.3 6.1 8.3 7.3 23.5 64.5 9.3 6.1 8.2 6.4 4.4 11.5 15.3 0.0 45.9 18.8 14.9 10.3 87.4 57.1 12.5 8.1 12.4 18.2 13.6 9.3 6.9 10.6 29.8 6.6 21.8 19.4 14.7 25.7 28.1 11.8 33.1 25.2 8.1 11.7 16.7 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437301 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 118.8;Excitatory neurons: 201.0;Inhibitory neurons: 198.3;Microglial cells: 144.3;Oligodendrocyte precursor cells: 160.4;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "AF22: 102.3;RT4: 97.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 15.8 17.1 11.6 6.7 12.5 10.5 16.6 21.6 16.7 15.0 15.3 15.5 13.2 17.2 13.4 10.2 13.6 14.7 19.3 14.2 11.2 24.5 15.1 13.3 6.1 9.9 10.0 20.2 12.2 25.3 12.2 27.4 10.0 16.9 13.0 28.0 10.8 14.0 30.9 16.4 14.3 14.5 11.3 11.6 26.6 21.3 10.2 8.1 24.4 22.2 6.1 18.3 11.4 14.4 25.6 15.6 102.3 16.3 16.3 32.4 28.0 22.1 28.3 21.6 18.3 13.3 12.6 5.5 24.3 15.3 22.1 13.6 39.0 19.7 32.6 6.3 16.0 9.2 10.8 30.9 42.3 4.0 14.5 29.3 19.0 28.1 30.1 22.6 18.8 5.0 12.1 9.9 29.2 13.9 9.0 6.0 30.7 24.0 23.4 9.9 33.3 4.2 28.3 97.3 18.2 20.7 12.9 20.7 58.8 32.0 13.9 5.6 15.4 16.7 19.7 15.0 12.1 15.1 9.3 1.9 20.5 6.6 19.0 0.7 0.1 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.4 0.1 0.1 0.0 11.6 12.5 21.6 16.7 14.2 11.2 9.9 10.0 10.0 11.3 10.2 14.4 36.2 3.2 8.4 118.8 8.1 17.6 17.9 11.0 16.5 24.7 14.1 12.3 38.2 21.5 16.5 22.0 25.0 13.1 4.1 12.5 19.6 10.3 45.1 22.3 19.9 20.6 9.6 4.6 201.0 12.4 6.7 18.2 25.5 59.4 2.5 15.6 14.3 18.6 9.7 6.7 198.3 13.9 2.0 10.9 20.6 103.0 20.8 14.4 5.4 144.3 4.4 13.2 3.1 160.4 129.2 17.5 5.7 17.7 14.3 18.6 14.0 11.9 19.5 37.9 19.7 18.7 17.6 22.6 19.8 11.8 19.2 10.4 5.9 17.4 10.6 30.2 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 341.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nuclear speckles" "CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 31.1 33.1 64.8 35.9 84.4 41.2 29.8 37.3 80.9 31.4 32.9 36.1 25.8 29.6 30.1 43.0 29.0 28.9 42.2 91.3 46.4 42.1 34.2 38.5 36.8 29.1 45.1 29.2 38.1 51.7 12.0 33.1 35.9 32.8 36.2 30.3 28.9 32.7 38.1 45.0 29.5 39.1 43.8 40.5 33.9 43.7 60.1 44.4 46.1 41.9 41.9 35.5 18.9 43.2 78.7 48.0 60.5 37.2 75.9 76.7 25.9 84.7 77.5 73.2 72.0 43.8 40.8 45.8 41.3 112.7 67.5 74.6 73.9 67.9 97.8 180.4 72.1 78.9 43.0 67.7 73.5 113.2 80.5 56.9 60.1 89.4 81.6 58.0 101.7 45.4 341.9 50.5 97.5 36.6 72.0 38.5 24.4 104.5 46.8 79.4 149.6 13.2 55.5 62.9 50.0 28.6 91.5 64.2 57.2 60.4 42.4 47.1 90.1 61.5 79.6 71.9 54.2 47.1 59.4 65.8 60.0 60.0 68.4 1.4 4.9 7.2 15.9 6.0 4.9 2.3 3.6 6.0 4.1 2.6 3.5 6.1 16.5 9.3 6.9 4.0 3.4 4.0 64.8 84.4 37.3 80.9 91.3 46.4 29.1 45.1 35.9 43.8 60.1 43.2 36.8 48.1 35.8 97.6 44.0 60.2 28.4 25.1 28.5 25.5 32.5 24.5 41.5 42.9 31.2 51.5 54.2 21.8 151.7 74.4 19.6 28.5 49.0 33.5 40.3 39.9 59.6 63.8 109.2 39.2 23.2 38.4 52.0 45.0 92.8 28.8 52.1 63.5 53.2 28.6 91.2 42.2 26.4 89.0 77.1 14.7 32.6 74.9 40.9 68.4 75.0 35.8 143.2 82.4 75.1 45.3 35.2 44.4 37.0 43.8 32.8 46.0 32.2 22.4 32.9 44.6 37.3 74.1 53.4 44.9 61.8 19.2 91.4 43.3 38.6 38.8 MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027677-36111236 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 79.0;neutrophil: 24.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 79.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 970000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear speckles" Cytosol "CAB010285: AB_632140, CAB040578: , HPA051825: " "unprognostic (6.76e-3)" "unprognostic (6.28e-2)" "unprognostic (6.30e-3)" "unprognostic (3.30e-3)" "unprognostic (6.98e-2)" "unprognostic (4.04e-2)" "unprognostic (8.10e-2)" "unprognostic (1.93e-1)" "unprognostic (2.20e-3)" "unprognostic (8.39e-2)" "unprognostic (6.27e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-2)" "unprognostic (3.66e-3)" "unprognostic (6.66e-2)" "unprognostic (3.25e-1)" "unprognostic (1.58e-1)" 29.9 26.1 15.2 31.5 16.5 89.3 23.8 19.2 17.1 30.8 19.3 26.6 27.9 37.2 15.8 32.3 25.7 23.5 25.7 17.2 18.2 23.9 41.4 28.3 28.0 11.5 11.7 22.2 18.3 20.6 19.3 44.6 12.1 19.6 29.0 14.8 21.0 24.4 33.5 34.4 26.2 39.0 13.0 44.9 22.5 9.1 18.1 38.6 31.1 31.9 33.3 32.3 29.2 13.8 49.7 26.7 28.3 44.9 60.0 59.8 62.2 50.2 64.8 58.7 60.3 67.3 24.8 40.4 49.6 54.9 28.0 34.8 47.2 43.7 60.9 47.3 37.6 94.9 37.2 53.1 33.2 60.3 54.9 43.1 40.5 42.2 40.9 47.6 67.1 67.2 52.4 49.1 40.3 21.1 62.2 62.5 17.0 29.9 26.2 71.7 45.5 37.5 38.5 67.6 21.8 17.2 46.0 33.5 50.3 34.1 40.8 99.9 47.9 52.5 29.8 33.6 47.7 24.3 59.8 39.5 23.2 112.1 43.9 79.0 10.3 6.3 4.5 7.2 5.5 3.1 4.4 5.1 8.2 5.3 4.6 4.7 24.9 6.1 10.8 4.0 5.8 5.1 15.2 16.5 19.2 17.1 17.2 18.2 11.5 11.7 12.1 13.0 18.1 13.8 24.4 32.1 13.9 37.2 22.6 15.9 11.0 13.9 28.5 18.9 14.0 11.7 25.0 14.3 18.5 18.4 31.3 45.4 26.8 29.0 1.9 13.9 3.6 18.7 25.8 22.6 16.8 47.1 104.9 11.3 18.7 25.9 21.9 30.7 21.0 17.7 28.9 52.9 25.3 11.8 79.2 25.4 10.2 51.7 24.9 5.2 24.5 38.5 10.6 52.5 58.7 10.9 39.1 46.8 69.6 22.8 16.2 26.7 27.7 10.3 33.7 17.2 20.9 22.5 13.1 20.4 15.7 9.9 8.5 27.1 19.0 23.9 28.0 12.3 18.8 10.7 MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 336.9;Early spermatids: 267.2;Proximal enterocytes: 235.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 49.1;neutrophil: 21.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 49.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported Nucleoplasm NA NA 46000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" 99.5 64.3 178.7 42.4 162.3 45.2 86.3 113.0 200.9 93.3 86.0 117.2 103.1 74.9 27.4 129.6 71.6 65.3 65.4 168.6 132.7 49.4 21.2 71.3 37.8 135.6 148.7 78.7 33.7 61.2 55.8 70.2 142.3 49.2 91.9 71.5 61.0 43.3 51.7 77.6 113.2 58.7 127.4 57.4 86.4 31.6 129.5 31.4 58.0 57.0 49.3 64.8 89.0 130.9 56.3 30.0 62.2 35.7 153.7 202.4 35.1 40.7 101.1 63.4 75.3 36.4 110.0 56.3 39.7 115.5 73.2 20.6 53.3 47.8 61.0 106.9 61.8 17.3 31.6 61.8 154.2 13.0 46.2 125.8 27.3 72.5 32.2 96.1 163.7 60.3 24.3 70.0 85.2 147.1 59.2 21.5 16.9 113.6 26.1 68.9 37.3 127.4 58.0 35.0 55.2 39.3 23.2 81.8 24.1 50.5 53.5 30.7 117.2 41.7 35.4 48.4 14.5 79.1 39.3 29.6 83.3 27.1 30.0 6.2 5.1 49.1 1.6 3.7 2.6 2.3 3.7 3.0 2.8 2.5 2.6 2.9 21.5 2.2 2.0 2.8 6.6 2.8 178.7 162.3 113.0 200.9 168.6 132.7 135.6 148.7 142.3 127.4 129.5 130.9 95.5 22.4 17.5 7.5 10.7 9.8 22.2 11.4 5.7 30.4 23.3 19.9 15.4 20.0 13.0 9.2 22.9 77.6 15.2 336.9 23.5 39.8 267.2 24.8 25.1 68.1 54.7 6.1 7.7 61.2 134.2 34.7 79.0 15.7 2.5 19.1 71.7 7.0 45.2 8.4 10.3 159.3 22.4 26.4 12.3 176.0 32.3 20.6 23.2 7.5 24.5 67.0 13.4 7.1 9.8 118.8 167.2 27.4 6.2 13.5 235.6 23.9 24.7 41.5 19.7 18.8 29.3 10.9 19.8 15.8 13.2 33.8 14.5 40.0 94.9 22.4 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 43.1;SuSa: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: AB_2673706" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 8.3 13.7 4.0 4.0 4.4 5.2 7.7 4.0 5.9 14.3 4.4 10.6 5.5 11.1 3.3 16.3 8.7 4.5 6.2 3.9 4.5 7.7 3.9 8.7 3.7 5.3 6.1 12.5 3.4 2.9 6.1 6.7 4.4 8.9 3.5 2.2 6.7 6.1 5.0 12.5 7.3 6.7 3.3 9.4 6.7 11.8 5.0 3.5 7.4 3.4 3.6 10.1 15.2 4.1 6.9 11.0 9.9 7.7 43.1 17.2 10.4 9.0 8.3 13.0 12.4 12.2 1.4 4.1 7.3 16.5 10.4 8.2 10.4 9.4 7.8 7.2 8.3 1.9 8.4 5.4 21.2 1.9 7.8 21.6 6.2 18.2 7.2 12.0 9.5 7.5 3.7 1.4 13.2 4.8 13.0 7.4 10.7 8.4 6.7 8.6 12.9 3.0 5.4 3.7 4.4 12.3 9.7 1.0 5.0 53.7 6.1 3.1 6.0 14.6 10.8 15.5 6.7 2.6 4.0 1.2 16.5 1.6 9.2 0.8 3.4 10.7 3.7 6.5 2.0 1.8 1.8 3.2 2.3 1.0 1.6 2.0 1.1 4.9 6.0 1.4 1.0 3.1 4.0 4.4 4.0 5.9 3.9 4.5 5.3 6.1 4.4 3.3 5.0 4.1 10.7 6.4 3.3 2.6 7.8 5.5 6.1 9.5 13.6 2.4 5.8 4.6 5.3 2.8 5.6 5.5 2.1 5.7 6.7 16.2 5.9 8.1 8.7 3.0 7.9 8.5 10.7 1.7 2.0 6.2 8.0 9.6 12.2 5.2 2.5 7.7 7.5 1.1 7.7 0.0 2.1 6.9 10.2 6.9 6.1 5.7 11.5 14.4 3.6 6.5 3.4 13.1 17.5 1.0 2.0 8.0 20.8 11.7 9.3 6.3 9.0 3.5 3.2 2.1 26.3 8.4 11.1 33.2 16.4 9.8 4.3 5.1 6.2 7.7 6.7 5.3 MAPK8 "JNK, JNK1, PRKM8, SAPK1" ENSG00000107643 "Mitogen-activated protein kinase 8" P45983 10 48306639-48439360 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 160.5;Excitatory neurons: 199.1;Inhibitory neurons: 218.2;Oligodendrocyte precursor cells: 233.7;Oligodendrocytes: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004463, CAB069396" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "CAB004463: AB_675868, CAB069396: AB_1619977" "unprognostic (7.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.74e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (8.66e-4)" "unprognostic (4.23e-2)" "unprognostic (5.98e-2)" "unprognostic (4.31e-3)" "unprognostic (2.33e-1)" "unprognostic (6.06e-2)" "prognostic favorable (8.66e-4)" "unprognostic (1.58e-1)" "unprognostic (9.95e-2)" "unprognostic (1.85e-2)" "unprognostic (1.01e-3)" 7.2 6.7 11.3 7.0 12.6 11.3 13.8 18.3 12.8 8.8 4.5 9.0 10.4 11.0 7.7 9.4 7.5 9.2 7.2 12.5 9.4 13.6 15.6 6.7 7.8 11.6 9.7 11.0 7.5 8.6 7.9 8.3 13.1 8.3 9.9 21.9 9.6 8.2 11.7 6.5 11.2 9.6 8.8 6.7 8.1 13.1 10.9 13.8 14.1 9.6 9.6 8.3 7.0 12.8 29.2 7.2 21.8 12.8 11.3 10.4 16.5 37.9 23.6 20.0 17.8 7.7 19.2 10.9 10.5 21.3 10.7 13.1 10.2 15.2 31.2 45.4 16.5 15.9 6.8 12.7 16.0 24.2 13.2 9.5 18.5 14.4 21.8 12.5 22.0 22.4 25.1 14.5 13.2 8.6 22.1 15.4 14.4 10.0 4.7 17.8 25.8 12.6 17.1 11.1 38.3 34.8 13.5 11.9 16.1 14.8 12.4 11.4 16.7 14.4 31.9 14.6 30.4 6.2 18.0 16.4 14.3 24.9 8.7 0.0 1.1 1.4 1.1 1.1 2.1 0.6 1.7 1.3 1.0 0.8 1.7 1.0 0.8 1.3 1.4 1.8 1.1 1.0 11.3 12.6 18.3 12.8 12.5 9.4 11.6 9.7 13.1 8.8 10.9 12.8 21.2 3.2 17.1 145.3 21.9 44.7 50.6 19.3 20.5 56.2 34.4 17.7 10.0 22.8 18.0 7.3 31.3 15.5 22.3 19.1 11.7 28.9 160.5 25.7 21.9 22.0 31.0 12.4 199.1 25.3 7.4 21.8 16.3 42.9 12.0 25.8 10.4 22.3 9.8 70.7 218.2 16.5 28.5 11.0 34.9 99.2 14.6 18.4 21.4 93.7 25.4 18.9 11.3 233.7 163.0 35.9 22.5 10.1 31.2 39.3 25.4 24.3 16.6 34.6 6.6 23.0 24.5 28.1 28.1 17.5 36.7 15.7 21.6 41.0 11.9 45.5 MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 166.8;pituitary gland: 118.2" "Cell type enhanced" "Detected in many" "Early spermatids: 43.8;Enteroendocrine cells: 40.2;Horizontal cells: 67.3;Late spermatids: 39.2;Muller glia cells: 41.3;Oligodendrocytes: 48.7" "Cancer enhanced" "Detected in all" "glioma: 51.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332, HPA079657" Approved Enhanced "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA058921: AB_2683854, HPA070332: AB_2686254, HPA079657: " "unprognostic (3.96e-2)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (6.88e-2)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (8.25e-3)" "unprognostic (3.42e-3)" "unprognostic (1.27e-2)" "unprognostic (9.54e-2)" "unprognostic (3.22e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.23e-11)" "unprognostic (7.19e-2)" "unprognostic (4.01e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-3)" 4.8 23.3 127.9 2.3 131.0 1.3 4.8 122.0 147.7 8.2 29.6 8.3 1.4 10.9 3.5 2.2 11.3 3.5 5.5 166.8 120.6 11.5 5.6 4.0 0.6 154.9 130.9 9.1 43.1 19.2 118.2 1.4 142.6 11.6 1.2 11.5 11.4 6.1 2.4 4.0 3.7 5.7 124.6 2.3 9.0 27.7 139.3 1.0 7.0 2.5 0.4 6.7 4.8 164.4 0.0 7.1 9.4 26.2 3.4 1.8 0.3 5.1 4.6 9.9 7.2 6.3 1.1 0.4 2.5 5.9 16.8 5.8 10.2 4.8 4.4 4.0 13.1 0.1 8.6 4.1 3.1 0.6 4.4 2.4 1.0 6.4 1.3 6.6 2.2 0.9 11.5 1.6 2.8 3.9 0.4 0.6 24.9 3.3 10.5 0.6 15.4 0.3 4.6 0.2 76.4 28.5 8.4 6.8 10.0 3.6 11.0 0.4 2.1 12.5 19.1 19.0 9.3 1.1 1.3 0.5 7.9 0.2 3.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 127.9 131.0 122.0 147.7 166.8 120.6 154.9 130.9 142.6 124.6 139.3 164.4 1.7 6.4 4.1 7.2 0.9 2.4 5.8 2.0 2.8 34.4 6.1 5.3 1.1 5.7 3.3 11.0 22.9 1.6 0.4 2.2 13.7 6.9 43.8 23.9 15.9 2.9 40.2 0.0 10.3 28.9 0.6 6.5 4.1 19.9 0.0 2.8 0.4 4.6 0.5 67.3 11.6 1.6 4.1 0.8 3.5 39.2 6.2 1.1 3.6 1.0 1.6 41.3 0.0 3.5 48.7 11.6 0.5 6.4 0.1 6.3 1.4 8.9 10.9 18.3 0.0 14.2 6.0 10.6 8.2 0.9 1.0 5.7 1.3 7.7 0.9 5.5 MAPKAPK2 MK2 ENSG00000162889 "MAPK activated protein kinase 2" P49137 1 206684905-206734281 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 21.9" "Lineage enriched" "Detected in all" 6 "dendritic cells: 21.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010297, HPA045556, HPA063708, HPA064435" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Centrosome "CAB010297: AB_2250405, HPA045556: AB_2679367, HPA063708: AB_2685100, HPA064435: AB_2685263" "unprognostic (7.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (4.58e-6)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (6.96e-2)" "unprognostic (3.29e-2)" 61.9 80.4 34.8 56.2 39.1 174.6 50.5 36.9 33.9 47.3 38.7 50.3 65.5 53.3 24.1 55.8 50.8 52.5 190.1 30.8 36.6 79.5 66.8 79.3 57.8 53.1 42.1 44.8 53.8 38.0 63.3 25.7 43.9 42.8 35.3 17.6 54.9 33.1 196.7 54.4 61.7 45.4 40.1 78.3 68.2 46.9 45.2 45.6 47.7 94.3 54.4 63.5 46.6 38.6 85.4 33.1 44.8 50.6 128.4 75.0 55.1 57.3 130.0 86.0 80.7 63.8 40.4 40.6 38.8 116.9 54.1 63.0 33.8 61.7 61.4 46.5 25.4 69.1 41.7 41.3 99.0 102.3 219.5 104.1 77.3 82.8 91.3 71.8 71.7 54.1 79.7 180.2 70.5 105.2 41.2 73.3 51.5 29.9 45.1 103.7 94.0 13.5 64.9 51.5 35.7 45.7 68.0 114.2 83.1 83.0 55.4 97.2 68.7 77.6 64.7 91.0 79.7 232.0 220.6 33.2 87.8 60.9 26.0 1.6 0.8 1.8 1.8 1.4 1.6 1.1 1.3 1.7 0.7 1.2 0.6 1.2 3.7 2.6 1.3 21.9 1.8 0.7 34.8 39.1 36.9 33.9 30.8 36.6 53.1 42.1 43.9 40.1 45.2 38.6 49.2 54.5 49.9 15.7 27.9 85.4 52.3 18.3 20.5 12.4 61.4 37.8 102.5 37.1 26.8 31.3 20.9 6.4 185.9 51.9 15.6 30.6 76.2 32.2 40.9 43.7 61.7 15.4 4.7 58.5 9.2 33.4 32.1 46.6 34.9 24.8 19.2 40.0 24.8 0.0 10.6 38.1 16.2 34.6 82.7 36.1 22.7 60.9 33.8 13.1 23.7 21.7 74.2 8.5 17.4 61.6 34.4 17.3 69.6 67.3 22.2 25.0 14.4 16.0 26.3 36.9 48.5 13.7 10.3 31.5 72.0 16.6 46.0 19.2 30.5 75.0 MAST2 "KIAA0807, MAST205" ENSG00000086015 "Microtubule associated serine/threonine kinase 2" Q6P0Q8 1 45786987-46036122 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 170.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.9;Inhibitory neurons: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039722, HPA040155" Approved Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA039722: AB_10795294, HPA040155: AB_10793957" "unprognostic (7.80e-2)" "unprognostic (3.02e-2)" "unprognostic (5.77e-2)" "unprognostic (1.52e-1)" "unprognostic (3.82e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (4.31e-8)" "unprognostic (8.86e-2)" "unprognostic (2.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (6.85e-13)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.90e-1)" 18.3 11.8 16.2 11.0 15.5 8.0 18.7 15.4 17.5 57.4 7.3 39.1 21.9 43.5 12.8 14.7 31.2 19.0 65.3 15.2 19.4 12.2 18.9 17.8 8.9 19.7 27.7 51.9 9.2 13.9 27.0 8.6 26.4 40.0 25.3 24.0 18.4 15.4 170.6 14.6 30.7 26.3 14.6 7.2 24.0 56.3 18.3 5.8 13.2 73.1 11.1 46.9 28.8 15.7 31.7 25.1 24.7 19.2 30.7 41.4 27.6 32.2 22.8 29.4 32.6 29.4 10.1 48.8 15.2 38.6 59.9 15.7 30.1 18.8 30.4 23.7 16.4 22.2 29.2 27.4 28.4 12.0 27.3 34.1 23.7 49.8 37.0 35.2 27.5 12.5 17.3 14.6 34.2 21.9 17.7 12.5 20.4 21.2 28.2 25.6 40.7 9.4 16.1 16.8 34.0 20.6 38.0 50.4 16.3 26.9 22.8 11.9 27.9 55.7 36.8 30.1 33.0 19.5 18.9 17.5 38.0 16.0 24.2 0.0 0.3 0.4 0.3 0.2 0.4 0.0 0.2 0.4 0.6 0.1 0.1 0.2 0.0 0.5 1.5 0.0 0.0 0.2 16.2 15.5 15.4 17.5 15.2 19.4 19.7 27.7 26.4 14.6 18.3 15.7 5.5 0.0 2.0 32.0 2.3 4.2 4.1 3.0 8.0 15.8 8.2 6.7 46.5 4.3 5.5 3.7 54.2 6.1 2.4 66.9 1.9 4.6 38.0 4.4 17.0 7.3 12.1 6.5 45.4 6.3 4.8 12.0 12.8 7.8 0.0 13.0 3.6 6.6 6.2 5.0 86.6 24.6 0.0 2.8 7.8 57.7 9.0 5.3 7.2 30.9 2.5 3.7 7.2 52.3 52.5 8.3 33.9 10.1 5.5 10.7 50.2 5.7 3.1 12.8 6.6 11.7 9.0 28.0 13.2 6.3 2.7 5.5 3.5 12.4 22.4 7.4 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;brain: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 177.0;Hofbauer cells: 57.4;NK-cells: 422.2;T-cells: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 76.8" "Group enriched" "Detected in many" 57 "NK-cells: 76.8;T-cells: 46.2" "Cell line enhanced" "Detected in some" "HL-60: 108.3;HMC-1: 30.9;K-562: 48.9;MCF7: 34.4;NB-4: 74.8;SCLC-21H: 30.9;THP-1: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 4.7 1.3 18.3 6.6 21.3 20.5 2.5 2.9 41.9 1.1 1.6 2.1 6.6 0.9 0.1 2.1 4.0 4.4 1.4 25.9 8.7 2.4 3.2 9.9 9.4 10.4 11.0 0.7 1.2 0.7 2.7 1.0 8.8 1.3 1.1 2.2 3.2 0.7 0.8 1.9 6.2 0.8 4.7 16.5 4.0 3.1 14.1 3.8 1.6 0.2 4.0 1.6 1.1 23.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.7 0.0 1.0 10.6 13.8 0.4 0.0 0.0 18.1 12.0 1.5 2.9 0.0 108.3 30.9 0.1 0.0 0.2 0.1 0.0 0.0 1.2 48.9 0.1 0.0 34.4 0.3 74.8 8.4 9.0 0.3 0.0 0.1 0.0 0.0 0.0 30.9 0.1 0.1 0.1 0.1 0.9 0.0 27.4 3.3 0.0 0.6 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 46.2 0.0 31.3 0.0 5.7 29.3 0.8 0.9 2.7 16.4 1.0 76.8 0.2 0.3 0.4 7.6 18.3 21.3 2.9 41.9 25.9 8.7 10.4 11.0 8.8 4.7 14.1 23.6 1.4 0.0 1.1 0.3 11.1 0.4 0.1 0.0 0.0 1.4 4.9 7.2 1.3 0.0 0.0 0.0 12.5 0.3 177.0 0.3 0.0 0.0 2.0 0.2 0.5 1.9 7.1 28.6 17.7 0.0 0.5 0.8 11.7 0.5 44.5 0.1 8.6 1.1 57.4 0.0 8.3 0.3 0.0 6.0 14.6 5.1 0.0 11.5 1.8 4.7 3.0 1.3 422.2 2.0 1.6 0.0 1.1 0.0 17.1 0.1 0.3 0.2 0.7 2.0 0.0 0.5 1.2 0.4 4.5 1.3 1.1 0.3 99.7 0.0 1.1 0.0 MAX "bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8" ENSG00000125952 "MYC associated factor X" P61244 14 65006174-65102695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 390.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000328, HPA003474" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Golgi apparatus, Vesicles" "CAB000328: AB_2281783, HPA003474: AB_1079317" "unprognostic (4.50e-3)" "unprognostic (1.51e-3)" "unprognostic (4.08e-2)" "unprognostic (2.87e-1)" "unprognostic (8.37e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (1.30e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-3)" "unprognostic (7.19e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.68e-2)" "prognostic favorable (2.12e-4)" "unprognostic (6.03e-2)" 48.1 36.3 57.4 43.5 63.2 105.1 41.2 74.6 62.9 61.0 44.8 51.1 41.3 51.1 29.2 75.8 67.2 36.2 52.8 55.0 59.4 39.5 36.8 51.6 63.7 65.5 61.8 56.2 29.3 31.3 32.5 39.8 65.0 52.2 31.8 23.6 43.5 38.7 43.8 55.3 51.7 39.5 59.4 66.3 39.4 21.5 62.1 63.7 42.7 54.0 55.1 51.3 68.7 65.3 117.1 40.4 27.8 44.6 73.4 58.0 35.4 39.9 62.3 47.5 58.4 29.1 86.7 88.1 33.1 48.8 45.0 60.4 63.4 52.7 37.3 84.5 40.5 143.4 29.9 32.0 90.9 56.2 390.3 67.6 43.5 42.7 54.9 71.9 54.9 71.8 66.8 42.4 53.1 63.9 140.1 217.6 36.3 71.3 70.6 75.2 42.7 47.3 49.2 38.8 61.8 38.2 49.6 60.6 60.4 25.1 58.0 71.6 69.7 47.8 55.8 42.0 33.6 50.7 43.6 61.7 56.9 56.1 46.0 667.6 141.9 540.8 125.7 126.4 140.1 115.7 147.5 130.5 119.9 114.9 151.1 127.9 305.1 126.9 120.3 114.6 194.0 314.2 57.4 63.2 74.6 62.9 55.0 59.4 65.5 61.8 65.0 59.4 62.1 65.3 45.8 28.9 27.4 31.0 74.5 170.2 66.0 63.3 126.3 28.2 59.8 43.1 27.4 32.9 42.0 18.4 20.9 38.4 79.1 116.3 52.8 38.8 45.5 38.1 43.6 59.9 44.3 40.4 50.7 31.4 43.4 46.7 32.6 36.0 62.8 38.2 71.0 23.8 59.9 47.1 43.3 49.7 38.7 81.8 66.7 115.6 77.9 147.2 56.9 32.8 67.1 47.3 69.0 28.1 60.4 61.6 96.7 60.2 58.0 80.3 100.6 66.4 32.9 16.9 138.1 47.4 76.3 43.2 28.4 84.8 180.6 54.0 83.9 25.4 29.7 76.2 MBD1 "CXXC3, PCM1" ENSG00000141644 "Methyl-CpG binding domain protein 1" Q9UIS9 18 50266882-50281774 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 97.4;Spermatocytes: 136.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009017, CAB036003, HPA068850" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "CAB009017: AB_2095559, CAB036003: , HPA068850: AB_2732121" "unprognostic (2.12e-2)" "unprognostic (5.05e-2)" "unprognostic (6.88e-2)" "unprognostic (5.01e-3)" "unprognostic (9.20e-2)" "unprognostic (6.85e-2)" "prognostic unfavorable (5.08e-6)" "unprognostic (5.91e-2)" "unprognostic (2.61e-2)" "unprognostic (4.65e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (1.70e-6)" "unprognostic (7.06e-3)" "unprognostic (7.70e-2)" "unprognostic (7.05e-2)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 28.5 39.8 23.9 26.2 25.9 44.2 29.1 24.8 28.2 32.3 19.3 35.7 24.8 32.1 20.5 39.2 31.6 19.6 35.7 26.7 22.2 32.5 35.7 29.9 30.2 23.1 22.0 34.8 34.5 32.4 42.8 24.6 21.1 33.0 17.7 24.0 30.5 23.5 51.0 43.4 33.7 20.4 19.5 41.0 33.6 88.1 23.1 29.6 35.4 28.6 24.2 35.3 32.2 25.6 30.9 28.6 31.5 35.9 33.2 26.9 33.9 36.2 41.4 49.2 37.7 21.6 23.9 48.5 25.8 35.3 28.8 54.4 36.3 63.4 28.4 54.7 23.2 30.6 43.8 23.1 63.9 74.8 62.1 31.5 100.4 56.2 127.2 31.1 40.9 47.4 39.3 73.8 38.3 28.5 63.3 38.9 29.8 16.1 22.7 57.8 23.3 53.2 24.4 13.8 41.5 39.5 27.0 25.5 33.2 25.4 32.4 67.4 44.7 53.0 24.1 17.3 37.2 135.8 62.2 51.6 34.3 56.8 49.0 16.0 11.2 22.7 15.3 9.7 14.6 11.6 13.5 12.9 11.2 11.4 13.8 11.4 14.5 14.3 7.8 10.2 13.8 12.6 23.9 25.9 24.8 28.2 26.7 22.2 23.1 22.0 21.1 19.5 23.1 25.6 17.7 9.6 24.6 19.6 20.1 22.7 13.9 18.2 23.3 15.1 16.5 14.5 28.1 14.3 20.5 16.5 18.8 31.1 25.0 24.5 13.7 15.7 85.1 17.1 16.1 17.6 13.1 9.7 20.4 13.8 24.2 16.5 28.1 17.3 8.8 17.7 13.9 18.1 18.7 15.2 17.3 19.5 24.4 15.8 11.1 97.4 15.5 17.5 16.0 9.4 15.7 17.4 14.4 12.1 16.4 21.1 24.5 19.2 34.6 14.4 21.3 9.7 16.9 20.3 13.1 14.8 18.9 136.0 32.5 21.6 29.3 51.4 20.0 28.1 18.6 17.0 MBD2 ENSG00000134046 "Methyl-CpG binding domain protein 2" Q9UBB5 18 54151606-54224669 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037282, HPA067582, HPA067615" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB037282: AB_477234, HPA067582: AB_2685866, HPA067615: AB_2685872" "unprognostic (4.86e-2)" "unprognostic (7.21e-2)" "prognostic favorable (6.49e-4)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "unprognostic (2.47e-1)" "unprognostic (2.38e-3)" "unprognostic (2.35e-2)" "unprognostic (2.71e-2)" "unprognostic (2.36e-3)" "unprognostic (8.04e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (8.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-3)" "unprognostic (5.19e-2)" 26.9 10.5 6.5 19.2 8.9 20.3 19.9 9.5 9.4 16.0 6.5 17.3 12.0 11.3 15.8 29.5 11.3 11.5 14.9 6.8 8.9 16.7 16.9 16.4 32.1 7.6 8.3 11.4 17.4 16.5 9.2 18.8 7.7 13.4 16.4 14.3 19.4 15.1 15.4 25.4 15.5 11.9 7.0 21.2 13.9 31.5 7.9 20.1 31.0 16.8 35.2 21.0 20.1 8.2 29.1 13.2 23.2 11.7 27.3 23.0 22.5 26.5 33.9 30.6 26.6 8.5 15.8 68.7 13.1 42.1 13.5 45.1 20.1 36.6 33.4 50.2 11.1 10.2 20.4 18.3 28.2 32.7 17.7 20.2 40.3 23.5 34.1 20.3 35.9 20.7 8.0 62.0 28.0 14.0 33.1 18.1 24.2 11.3 17.2 21.8 13.9 27.9 44.5 29.9 25.6 10.8 21.0 21.1 14.7 30.3 10.9 16.3 31.2 31.1 14.1 10.9 24.4 65.1 38.3 52.5 27.4 27.4 19.0 0.0 1.4 0.7 0.6 2.6 0.9 0.7 0.7 1.0 0.8 1.3 0.3 0.6 1.2 0.2 5.0 0.7 1.5 0.4 6.5 8.9 9.5 9.4 6.8 8.9 7.6 8.3 7.7 7.0 7.9 8.2 71.1 28.9 21.0 30.3 44.9 49.3 37.3 21.2 13.1 19.3 46.0 35.3 35.8 24.3 23.0 33.1 16.7 14.3 57.6 51.2 7.9 26.3 1.9 62.1 48.9 38.0 16.3 22.7 42.5 58.4 49.4 32.7 21.9 103.3 8.2 32.0 32.2 25.2 30.3 21.9 38.3 35.9 10.2 142.6 38.7 4.8 25.1 82.2 26.6 43.1 69.3 45.9 8.2 32.2 49.5 54.3 28.0 26.4 53.7 51.5 35.7 23.5 30.0 27.0 26.3 39.0 35.2 6.5 6.1 54.6 62.5 18.3 47.7 43.0 38.7 79.5 MBD4 MED1 ENSG00000129071 "Methyl-CpG binding domain 4, DNA glycosylase" O95243 3 129430947-129440179 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002031 Supported Supported "Nuclear speckles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nuclear speckles" "HPA002031: AB_1079319" "unprognostic (2.70e-2)" "unprognostic (3.48e-3)" "unprognostic (1.18e-2)" "unprognostic (6.37e-2)" "unprognostic (4.31e-2)" "unprognostic (7.11e-2)" "unprognostic (4.70e-2)" "unprognostic (3.25e-2)" "unprognostic (2.02e-2)" "unprognostic (5.73e-2)" "prognostic unfavorable (2.18e-4)" "prognostic unfavorable (4.75e-4)" "prognostic unfavorable (2.73e-6)" "unprognostic (9.27e-2)" "unprognostic (1.59e-2)" "unprognostic (8.58e-2)" "unprognostic (3.35e-2)" 18.6 18.4 16.8 34.0 18.4 44.2 21.6 19.6 20.7 33.2 16.8 19.3 23.7 23.3 24.8 16.4 19.3 21.3 25.3 17.0 17.4 25.4 38.0 22.9 66.5 17.5 17.2 30.3 22.9 18.1 19.3 19.7 17.7 18.7 22.9 19.6 19.5 17.8 25.8 23.7 27.5 19.7 17.3 39.2 27.8 17.3 18.4 30.0 19.3 22.3 74.0 18.5 17.5 20.6 46.2 27.4 32.5 36.5 36.8 32.8 37.5 39.0 36.9 36.7 43.3 33.8 30.1 64.6 31.1 24.5 33.7 40.7 25.2 24.1 44.2 37.0 16.6 38.9 32.0 24.6 58.7 71.2 49.2 39.1 33.8 31.2 27.4 36.5 35.1 37.2 43.9 47.1 27.5 43.3 41.4 50.0 28.7 38.8 23.5 38.7 19.2 44.7 40.9 22.7 36.5 20.3 49.3 25.3 42.5 28.0 32.3 62.5 23.6 34.5 26.3 37.6 26.2 31.9 20.9 111.9 29.4 40.1 29.2 80.3 25.0 35.2 31.1 23.1 24.0 116.5 33.2 30.9 21.0 110.8 40.6 33.3 43.0 28.9 30.0 25.2 31.5 25.6 16.8 18.4 19.6 20.7 17.0 17.4 17.5 17.2 17.7 17.3 18.4 20.6 36.5 19.2 52.9 15.3 111.2 17.3 32.5 38.4 29.6 37.0 26.7 29.6 35.9 27.1 36.4 44.1 18.8 49.2 61.4 22.4 45.0 32.1 19.8 49.6 41.2 33.5 33.6 46.3 18.1 69.0 46.2 35.6 55.0 45.0 58.9 33.1 31.4 32.1 71.8 21.9 12.8 27.5 40.7 41.8 24.7 10.6 32.9 48.0 21.4 24.4 62.9 21.2 54.6 14.1 22.0 39.3 23.4 36.5 75.5 31.1 29.4 55.5 39.5 46.3 39.5 39.6 30.9 49.5 71.6 30.4 19.6 37.1 54.2 33.2 26.3 35.6 MCL1 "BCL2L3, Mcl-1" ENSG00000143384 "MCL1 apoptosis regulator, BCL2 family member" Q07820 1 150560895-150579738 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 685.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 106.3" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "U-698: 4726.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002781, HPA008455, HPA031125, CAB068195" Enhanced Enhanced Mitochondria Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB002781: , CAB068195: AB_2665695, HPA008455: AB_1079334, HPA031125: AB_10602026" "unprognostic (3.82e-2)" "unprognostic (8.79e-2)" "unprognostic (9.15e-2)" "unprognostic (2.05e-2)" "unprognostic (1.34e-1)" "unprognostic (3.91e-2)" "unprognostic (3.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "unprognostic (8.60e-2)" "unprognostic (1.57e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.16e-4)" "unprognostic (3.22e-2)" "unprognostic (1.94e-1)" "unprognostic (4.87e-2)" "unprognostic (4.46e-2)" 297.8 149.2 72.9 264.9 75.0 685.1 175.0 77.0 84.2 143.4 85.0 137.1 99.4 98.5 41.8 199.3 190.7 278.8 139.1 65.3 81.5 125.2 404.6 237.1 161.2 86.4 77.8 105.3 161.7 89.2 82.8 146.9 79.4 96.3 120.1 90.1 124.7 56.4 153.8 189.2 133.6 171.4 80.6 171.5 167.0 41.3 91.4 128.9 133.3 160.1 157.1 302.6 124.6 75.8 140.2 74.8 131.9 73.3 262.9 262.2 175.8 164.8 174.5 173.0 139.4 91.9 112.3 184.9 102.2 120.2 80.3 187.7 101.7 203.3 166.7 154.8 68.3 76.4 109.9 106.2 204.7 130.6 151.3 147.3 221.3 170.6 330.0 159.5 192.7 49.4 168.1 225.3 234.2 160.3 64.6 80.7 242.0 122.9 131.9 94.7 111.1 85.9 195.2 103.7 95.9 134.2 125.6 135.9 232.4 191.2 100.4 195.2 251.6 109.2 119.4 55.5 212.8 310.2 409.5 4726.7 189.5 95.1 141.9 23.3 19.8 51.8 15.0 17.4 17.4 12.6 19.0 16.6 16.6 14.0 22.8 17.6 106.3 10.6 16.2 9.4 30.1 11.2 72.9 75.0 77.0 84.2 65.3 81.5 86.4 77.8 79.4 80.6 91.4 75.8 366.0 198.7 295.5 12.4 339.2 489.2 394.7 142.6 434.2 38.7 339.3 229.9 84.8 228.8 148.8 33.1 60.5 108.6 398.5 491.8 41.1 196.4 209.2 187.5 310.8 241.9 259.6 61.8 6.5 174.7 203.4 278.4 228.3 365.7 343.8 209.0 229.2 218.8 262.7 11.8 5.5 309.0 107.8 453.6 930.9 347.0 72.7 614.2 273.9 30.0 250.6 101.2 94.7 10.1 6.8 183.4 345.1 60.9 831.8 293.4 233.1 68.9 110.3 78.0 78.9 350.3 217.4 47.4 35.4 372.2 572.0 270.4 499.8 126.0 205.7 401.1 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.7;lymphoid tissue: 37.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.3;Erythroid cells: 65.6;Extravillous trophoblasts: 28.8;Spermatogonia: 25.9;Syncytiotrophoblasts: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 3.1 3.4 2.0 16.4 1.9 67.7 6.2 2.5 1.9 5.3 0.6 9.2 8.1 5.0 2.4 11.0 7.6 2.5 6.4 1.9 1.8 3.4 6.3 3.4 26.8 2.3 1.9 6.4 3.0 3.7 2.4 17.0 2.6 5.0 10.2 3.5 4.7 2.8 9.4 10.6 8.6 5.3 2.0 9.6 5.7 12.3 2.0 37.6 4.8 5.8 26.0 4.2 5.4 2.4 133.6 110.3 122.4 102.1 7.0 14.4 110.5 65.2 42.3 129.9 146.9 177.7 84.7 136.0 65.2 32.3 113.6 105.6 204.8 76.1 79.1 127.2 127.1 227.4 134.8 131.1 4.4 214.3 102.4 8.2 8.4 86.1 13.1 15.3 40.6 160.7 116.0 123.7 47.4 169.0 229.0 156.2 172.5 108.3 90.7 242.4 165.1 203.3 26.9 97.9 143.0 106.8 175.8 48.9 16.7 45.7 111.9 165.3 20.3 104.2 87.9 128.4 91.7 127.1 163.5 362.6 73.2 159.7 41.0 0.0 0.6 0.3 4.4 1.4 5.5 9.7 3.9 5.4 2.9 8.1 3.6 4.7 0.9 6.5 0.4 3.7 11.2 3.5 2.0 1.9 2.5 1.9 1.9 1.8 2.3 1.9 2.6 2.0 2.0 2.4 1.2 3.2 2.0 0.7 8.5 4.6 2.6 4.6 2.2 2.5 4.1 5.3 8.3 0.0 3.9 0.0 0.0 63.3 1.8 4.8 0.0 5.3 0.9 5.2 3.5 2.9 3.6 65.6 0.3 1.9 28.8 4.2 6.6 4.8 1.3 18.8 1.4 1.7 18.2 0.0 0.4 8.2 0.0 1.6 3.2 0.7 1.8 2.7 1.8 0.0 9.2 2.1 0.0 0.0 0.7 2.1 1.7 1.5 20.5 0.8 1.1 0.8 7.4 2.1 0.0 2.6 4.1 8.1 25.9 7.1 3.0 33.5 6.3 3.8 13.8 2.3 MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264014-52284881 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 122.7;Erythroid cells: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002162, HPA004789, HPA004790" Supported Supported Nucleoplasm NA Yes 150000 "Cluster 35: T-regs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB002162: AB_564115, HPA004789: AB_1079336, HPA004790: AB_1079335" "unprognostic (9.14e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.37e-1)" "unprognostic (1.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.01e-3)" "unprognostic (2.96e-2)" "unprognostic (1.15e-1)" "unprognostic (8.35e-2)" "unprognostic (1.16e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.34e-2)" 24.3 15.9 12.8 41.5 13.6 55.5 29.1 13.7 13.7 27.5 13.4 32.9 19.6 30.8 23.8 33.4 29.2 16.4 25.4 11.9 12.7 27.5 18.8 21.4 68.8 14.1 13.6 31.9 17.0 28.9 10.8 40.0 14.1 19.7 39.3 19.3 19.2 30.7 16.0 32.2 29.3 37.0 14.5 31.3 24.1 21.1 14.0 81.1 18.3 17.7 78.5 28.1 24.5 13.9 187.9 121.7 208.0 196.9 43.9 39.4 136.1 135.8 103.7 226.6 230.3 251.6 99.2 202.8 132.5 79.7 147.8 145.4 277.4 165.9 226.9 230.0 261.4 383.6 233.2 358.2 11.8 381.7 150.8 23.7 38.1 166.6 46.2 55.6 117.3 240.4 318.1 452.9 118.3 123.8 386.9 293.5 173.1 369.8 84.8 338.3 317.0 271.2 101.1 195.8 210.3 160.5 142.2 81.1 125.3 289.4 159.7 266.9 60.5 153.5 163.6 160.8 206.4 132.9 163.5 356.4 132.2 323.8 184.0 30.5 18.3 27.3 50.0 31.3 42.8 47.7 49.9 50.3 30.0 41.2 47.6 51.2 2.6 55.0 18.3 19.0 71.6 46.9 12.8 13.6 13.7 13.7 11.9 12.7 14.1 13.6 14.1 14.5 14.0 13.9 24.3 22.4 12.3 3.3 26.4 19.2 20.0 24.9 12.5 16.1 14.1 17.1 19.9 7.2 19.2 22.0 4.2 122.7 18.6 10.9 13.7 30.9 1.1 9.6 16.7 30.9 7.3 92.6 2.5 20.2 63.6 22.3 15.8 15.1 37.4 48.3 15.0 10.5 36.0 0.0 2.1 20.4 8.2 10.1 7.5 3.6 27.1 12.1 7.2 8.4 12.5 17.8 34.0 2.5 6.1 17.3 10.5 21.1 37.6 10.9 7.3 7.5 17.0 16.0 6.6 16.8 27.9 22.5 64.0 24.5 10.1 27.4 26.0 19.0 37.1 13.9 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.8;Erythroid cells: 96.6;monocytes: 137.7;Syncytiotrophoblasts: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 44000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 15.2 7.1 5.8 49.1 10.4 138.7 14.4 8.3 7.4 14.5 5.8 20.2 19.6 16.3 3.3 25.1 13.7 9.6 8.9 5.8 7.0 9.1 14.9 14.8 70.1 10.3 7.7 25.6 12.6 10.3 5.3 25.2 9.6 10.2 16.7 2.3 13.9 9.6 13.3 17.6 28.3 12.2 8.1 47.3 17.9 20.6 9.0 58.9 12.1 8.0 53.6 12.7 15.6 12.3 213.0 147.5 115.7 118.8 11.0 22.2 100.6 138.1 71.2 199.4 188.3 98.9 102.4 137.9 78.8 70.5 83.6 103.8 116.0 108.3 64.4 112.7 212.6 198.3 141.5 203.7 3.9 414.0 172.4 12.3 9.7 120.0 32.4 18.4 88.7 124.5 124.0 201.2 76.9 172.7 341.8 137.9 154.9 143.4 86.7 379.6 164.8 173.0 39.4 120.1 88.2 94.8 188.3 75.4 41.8 60.9 78.8 155.6 54.1 201.3 153.1 127.2 145.4 111.9 150.2 265.2 130.9 153.5 157.6 66.5 59.8 43.4 49.5 69.6 35.8 127.5 43.1 53.1 77.8 106.1 34.0 39.0 28.4 65.5 81.2 88.8 96.6 77.1 5.8 10.4 8.3 7.4 5.8 7.0 10.3 7.7 9.6 8.1 9.0 12.3 8.1 6.4 7.3 1.3 49.5 10.6 13.6 12.1 8.6 1.5 9.2 10.8 3.5 8.6 6.0 7.3 0.0 147.8 30.4 12.0 5.9 19.8 2.8 6.2 4.1 11.8 3.5 96.6 0.3 12.7 77.1 11.2 18.8 9.0 15.2 65.7 13.2 5.3 53.1 1.7 0.4 16.6 4.1 24.0 29.4 5.1 10.8 28.4 7.2 7.5 137.7 5.7 13.4 3.0 6.0 11.0 8.6 6.0 49.3 4.0 6.5 5.7 4.8 3.7 19.7 8.8 14.5 16.1 58.8 14.9 6.3 82.2 19.4 8.5 34.6 9.8 MCM7 "CDC47, MCM2, PPP1R104" ENSG00000166508 "Minichromosome maintenance complex component 7" P33993 7 100092728-100101940 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 180.8;lymphoid tissue: 156.4" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 132.9;Erythroid cells: 173.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002163, HPA003898, CAB016312" Enhanced Enhanced Nucleoplasm NA Yes 150000 "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB002163: AB_564113, CAB016312: AB_627235, HPA003898: AB_1853632" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-4)" "unprognostic (1.36e-1)" "unprognostic (5.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (2.18e-4)" "unprognostic (2.08e-2)" "unprognostic (5.79e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (9.34e-3)" "unprognostic (3.83e-2)" "unprognostic (5.41e-2)" "unprognostic (1.76e-1)" "unprognostic (1.32e-2)" "unprognostic (2.38e-1)" 22.9 14.2 56.4 50.2 61.7 180.8 32.0 51.4 70.4 17.4 45.8 45.3 38.7 29.7 13.1 31.2 25.6 18.2 17.0 48.8 50.5 13.7 26.3 23.0 82.4 58.5 59.8 37.0 24.1 15.1 8.9 35.0 55.1 20.4 50.8 10.6 21.3 22.2 25.7 44.9 41.3 32.3 55.1 29.4 27.4 49.4 55.6 156.4 20.4 28.5 88.5 21.6 11.9 60.8 310.1 359.5 399.9 306.7 28.7 35.5 214.4 195.7 165.5 374.9 407.7 281.9 335.2 469.2 184.6 112.0 321.6 252.5 439.3 241.6 303.9 238.6 498.1 274.7 251.9 248.9 18.9 553.6 226.2 30.1 43.4 306.9 179.6 61.8 154.0 295.1 542.2 444.6 200.8 786.2 940.1 442.9 361.9 295.2 236.4 572.5 517.7 651.6 92.3 221.5 253.4 397.0 264.9 294.3 104.9 217.9 126.2 314.4 81.0 198.1 346.7 379.8 411.1 200.3 311.8 875.0 135.9 463.1 354.3 3.7 4.0 4.3 14.1 7.5 10.9 9.1 10.3 13.2 9.3 15.0 11.2 10.5 1.4 15.9 13.3 11.3 17.2 11.6 56.4 61.7 51.4 70.4 48.8 50.5 58.5 59.8 55.1 55.1 55.6 60.8 23.2 9.6 17.9 6.2 34.5 46.7 28.5 25.7 37.0 9.4 30.8 36.3 9.6 11.5 13.3 3.7 14.6 132.9 32.5 42.3 9.8 28.2 54.7 11.8 16.3 23.8 17.4 173.6 4.0 26.2 102.7 22.8 40.8 19.8 24.1 67.3 10.4 10.3 40.4 6.7 4.0 48.8 18.3 10.4 22.2 32.0 21.1 17.6 19.6 3.7 14.1 11.1 18.6 12.1 11.7 16.7 22.8 15.4 59.8 20.8 19.0 11.5 18.0 12.5 13.1 30.7 46.0 90.0 79.8 41.3 35.4 72.0 29.4 14.9 79.0 22.9 MDC1 "Em:AB023051.5, KIAA0170, NFBD1" ENSG00000137337 "Mediator of DNA damage checkpoint 1" Q14676 6 30699807-30717447 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Spermatocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006915 Enhanced Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites" No No "Cluster 48: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Focal adhesion sites" "HPA006915: AB_1853669" "unprognostic (8.52e-2)" "unprognostic (4.32e-1)" "unprognostic (4.11e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-2)" "unprognostic (9.44e-2)" "unprognostic (2.74e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-2)" "unprognostic (3.86e-2)" "unprognostic (2.99e-1)" "unprognostic (4.39e-3)" "unprognostic (3.23e-1)" 11.3 7.0 2.7 8.6 3.2 13.0 10.9 4.1 5.2 12.4 3.3 11.0 4.9 13.7 8.5 6.2 12.3 4.6 9.5 2.4 4.1 8.2 9.7 9.5 10.2 4.5 3.3 16.8 10.8 8.6 12.8 7.4 3.5 10.1 6.9 14.1 9.1 8.2 11.0 9.4 10.9 8.9 2.0 11.3 8.4 28.2 3.4 14.5 16.4 5.8 11.3 10.7 9.3 3.6 36.7 11.1 47.4 34.8 6.3 10.0 23.0 14.8 10.0 25.2 21.3 22.7 8.5 37.7 17.5 17.0 23.5 20.2 63.0 28.6 34.9 29.9 65.6 43.4 28.7 12.5 4.1 27.1 16.9 7.9 9.2 48.6 27.3 9.0 11.5 25.7 61.0 36.7 19.1 14.7 14.6 20.0 20.6 8.4 7.8 33.2 24.7 37.4 11.0 10.7 39.9 23.2 11.5 26.2 13.5 29.1 21.8 16.8 13.8 24.8 26.4 19.2 26.3 19.3 21.6 34.5 7.8 63.9 34.3 0.1 0.1 0.1 0.6 0.1 0.3 0.4 0.4 0.5 0.1 0.7 0.5 0.5 0.0 3.2 0.1 0.7 0.0 0.3 2.7 3.2 4.1 5.2 2.4 4.1 4.5 3.3 3.5 2.0 3.4 3.6 9.7 16.0 13.0 10.1 13.4 4.5 5.5 5.6 15.9 11.5 6.8 8.6 7.6 7.2 5.7 5.5 8.4 7.9 11.0 2.5 3.9 5.3 4.7 8.0 8.7 9.7 6.7 14.5 8.3 6.2 11.4 11.2 4.1 13.7 17.1 12.8 6.1 12.0 6.7 5.0 8.1 3.3 12.2 6.0 5.7 3.9 7.8 7.3 1.8 11.2 5.9 10.6 14.4 12.5 9.9 5.2 1.1 6.0 16.9 2.9 1.2 3.0 8.0 17.1 13.1 16.2 8.3 74.5 18.0 8.7 3.7 1.9 12.1 7.7 6.0 1.9 MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1349.1;tongue: 1843.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1926.9;Proximal tubular cells: 1428.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434" "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favorable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" 274.6 213.6 235.9 86.7 249.7 79.1 137.9 245.9 353.6 89.6 230.2 167.7 154.7 82.0 161.3 125.3 114.5 87.2 1349.1 253.2 261.5 371.6 266.3 89.8 131.9 248.5 218.3 80.4 69.9 411.8 107.2 92.5 253.3 125.5 190.9 240.7 122.0 142.0 792.5 87.7 133.1 171.5 215.7 71.6 192.6 70.5 259.1 170.4 125.5 1843.8 165.4 131.5 62.8 237.7 268.2 219.5 257.8 173.2 369.6 280.9 282.3 215.1 295.9 300.6 304.1 252.5 215.4 355.2 112.8 264.1 358.8 214.3 303.0 355.0 425.5 207.6 253.1 337.0 173.2 376.8 202.1 384.1 223.9 277.7 241.3 271.5 152.7 236.2 235.3 308.1 183.7 217.3 395.1 157.8 300.6 317.5 158.0 376.3 266.5 235.2 349.7 310.5 460.9 251.0 249.9 153.6 182.5 257.7 384.1 205.6 191.9 341.9 149.6 220.3 211.9 187.1 252.9 264.6 264.8 407.6 266.2 312.2 184.1 271.3 186.3 200.2 202.7 267.8 218.8 258.5 236.6 224.6 241.0 258.5 230.3 221.6 28.1 214.6 253.4 184.3 320.9 321.2 235.9 249.7 245.9 353.6 253.2 261.5 248.5 218.3 253.3 215.7 259.1 237.7 44.4 60.9 54.3 54.9 78.7 81.6 109.4 562.9 50.7 165.4 81.0 86.7 1926.9 95.8 227.2 134.3 70.9 248.7 78.4 128.4 630.0 186.2 12.4 116.1 72.6 61.0 62.8 62.9 120.2 108.1 257.0 134.7 112.7 68.8 80.5 95.0 36.0 153.2 397.0 122.8 130.0 115.9 380.5 85.2 65.8 15.1 100.0 98.4 177.9 43.1 155.0 136.3 73.2 51.3 58.8 91.3 99.8 109.1 82.1 48.8 177.4 1428.3 224.5 164.1 59.2 68.3 167.8 58.0 65.6 82.7 84.0 149.5 84.3 137.4 167.8 102.6 MDK "FLJ27379, MK, NEGF2" ENSG00000110492 Midkine P21741 11 46380756-46383837 "Cancer-related genes, Predicted secreted proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 529.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 1010.4;Granulosa cells: 726.2;Paneth cells: 1272.7;Proximal enterocytes: 883.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;neutrophil: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 888.4;REH: 1343.8;SH-SY5Y: 1093.6" "CAB010055, HPA057126" Uncertain Approved Vesicles "Secreted to blood" NA NA 158000 960000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB010055: AB_627949, HPA057126: AB_2683344" "unprognostic (8.87e-3)" "unprognostic (6.65e-2)" "unprognostic (4.02e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.11e-2)" "unprognostic (4.01e-2)" "unprognostic (4.15e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (8.78e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" 41.1 98.0 23.3 22.9 23.3 11.7 82.2 27.0 37.0 379.4 16.3 78.0 263.3 208.2 60.3 38.1 170.3 140.0 36.1 21.6 40.7 35.9 8.5 48.5 20.3 31.8 27.5 529.1 30.5 103.9 370.4 32.0 22.6 128.7 38.0 5.9 137.4 84.1 7.6 26.9 211.3 49.5 24.6 78.1 108.3 16.8 31.5 92.9 26.8 9.8 15.9 84.1 129.3 24.6 51.1 66.5 758.4 2.5 5.2 62.2 18.6 39.2 77.0 145.6 128.8 505.2 219.5 3.4 528.6 58.5 6.3 429.6 431.8 0.7 13.3 157.0 91.6 22.5 5.6 703.6 336.2 1.7 3.5 100.0 13.2 89.2 0.5 31.0 214.3 28.9 385.2 3.5 83.3 348.6 19.8 9.4 888.4 275.9 388.0 1343.8 28.8 4.4 1.8 1.6 418.1 1093.6 128.9 11.3 11.0 665.8 347.3 349.5 59.0 221.1 526.2 3.1 27.2 2.9 11.0 5.1 6.5 13.7 197.3 0.0 0.0 0.0 0.1 0.2 0.0 1.8 0.1 0.2 0.0 0.4 0.0 0.0 2.1 0.1 0.2 0.1 0.9 0.4 23.3 23.3 27.0 37.0 21.6 40.7 31.8 27.5 22.6 24.6 31.5 24.6 108.2 0.0 5.4 5.5 9.6 11.1 162.1 392.4 12.5 1.3 245.2 218.7 7.0 34.3 393.6 47.8 0.0 162.3 5.4 499.0 1.9 286.0 26.4 134.6 490.2 115.0 1010.4 2.5 2.1 104.5 123.5 275.2 162.1 228.2 4.5 726.2 102.4 4.6 48.3 0.0 1.9 368.8 286.8 4.2 12.0 126.3 109.6 10.0 37.4 7.5 9.4 47.1 0.0 4.5 1.3 221.1 1272.7 18.8 18.6 163.6 883.4 19.6 109.5 1.1 85.5 26.1 197.0 31.8 34.3 26.2 8.1 153.1 11.4 8.9 187.6 511.1 MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808177-68850686 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 257.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 504.6;U-698: 517.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000086, CAB016303, CAB079977" Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB000086: AB_563872, CAB016303: AB_627920, CAB079977: " "unprognostic (1.16e-1)" "prognostic favorable (3.23e-4)" "unprognostic (6.16e-2)" "prognostic favorable (4.51e-7)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.77e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (3.23e-1)" "unprognostic (1.80e-3)" "unprognostic (2.36e-1)" "unprognostic (4.22e-2)" "unprognostic (4.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (8.95e-2)" 14.0 11.6 5.4 10.4 10.0 28.6 11.9 7.4 7.6 13.9 28.0 20.7 6.4 9.5 7.1 13.0 14.1 12.0 6.8 3.8 7.4 9.5 26.9 14.3 13.8 9.9 8.5 10.8 14.3 10.9 5.0 16.4 9.2 11.3 21.9 14.2 9.6 11.5 18.6 10.9 7.5 12.4 6.0 11.4 10.0 6.6 9.2 15.6 15.4 12.9 17.0 15.1 10.8 12.8 18.7 42.1 43.5 22.6 55.9 51.5 223.4 49.7 50.3 26.2 41.5 26.8 8.4 188.6 13.5 34.7 7.3 11.0 31.4 504.6 42.1 51.0 22.0 35.3 36.0 115.0 55.7 32.6 31.0 77.8 46.5 101.5 69.4 26.9 73.7 32.1 37.1 45.4 50.8 28.0 43.1 10.7 36.9 10.1 8.2 149.4 31.7 16.2 16.0 146.0 34.3 20.2 32.0 25.0 11.3 88.8 58.3 21.4 82.3 20.2 38.0 16.8 18.5 68.2 47.7 517.6 31.3 12.8 81.2 6.1 5.4 5.2 4.1 4.1 3.7 4.7 3.5 4.1 3.0 5.4 3.6 3.5 19.2 3.7 7.2 3.9 4.1 3.6 5.4 10.0 7.4 7.6 3.8 7.4 9.9 8.5 9.2 6.0 9.2 12.8 23.1 32.1 56.3 26.1 36.4 15.6 30.5 42.6 22.8 26.8 21.4 17.1 20.9 24.3 75.8 25.8 33.3 47.5 32.1 19.3 13.7 19.5 2.5 257.4 34.5 22.0 25.1 29.9 28.8 24.2 28.0 31.9 28.5 74.8 32.9 33.2 15.7 45.0 18.3 30.3 32.9 23.4 32.6 49.0 25.0 2.9 19.3 44.9 12.4 37.5 35.4 27.8 10.3 25.6 71.8 22.4 20.1 15.1 117.7 39.8 15.8 21.3 141.7 35.3 19.7 30.0 32.4 17.3 20.0 59.5 22.0 94.3 31.8 49.4 20.9 82.0 MDM4 "HDMX, MDMX" ENSG00000198625 "MDM4 regulator of p53" O15151 1 204516379-204558120 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018919, HPA048821" Approved Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA018919: AB_1853694, HPA048821: AB_2680531" "unprognostic (4.63e-2)" "unprognostic (3.73e-1)" "unprognostic (6.38e-2)" "unprognostic (1.50e-1)" "unprognostic (3.84e-2)" "unprognostic (1.68e-3)" "unprognostic (2.33e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-2)" "unprognostic (2.34e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (9.87e-4)" "prognostic unfavorable (7.06e-6)" "unprognostic (1.20e-1)" "unprognostic (1.73e-1)" "unprognostic (2.49e-2)" "prognostic favorable (2.49e-4)" 13.7 10.5 9.2 13.4 18.7 56.1 14.3 16.3 12.1 17.6 35.0 12.4 5.8 12.0 18.6 11.5 13.6 6.7 11.4 10.6 17.8 14.4 14.8 16.3 18.8 17.5 14.6 18.9 18.8 5.3 16.3 10.1 17.5 14.6 9.6 25.2 11.9 7.3 10.5 20.7 16.7 7.1 10.5 22.6 13.2 19.9 15.9 30.4 15.8 4.2 17.4 12.1 13.7 36.0 6.5 12.7 12.5 17.3 8.6 9.4 58.7 4.8 4.9 6.1 8.9 6.6 8.7 22.4 4.5 6.7 5.1 6.8 8.5 7.2 8.2 6.8 6.0 17.8 32.0 7.6 6.5 14.0 16.9 9.4 4.5 9.9 17.4 6.3 6.0 14.2 10.4 31.5 5.4 21.9 8.6 12.3 17.3 2.4 5.3 10.1 10.2 7.5 6.0 31.1 5.6 12.6 4.9 9.1 9.1 12.4 18.0 8.1 6.1 6.8 12.1 4.5 7.9 15.8 6.2 18.2 4.7 5.9 10.1 7.5 4.3 5.8 5.7 4.2 4.9 7.9 4.4 4.1 3.6 11.9 6.1 5.4 6.4 4.1 3.8 7.8 2.6 2.5 9.2 18.7 16.3 12.1 10.6 17.8 17.5 14.6 17.5 10.5 15.9 36.0 73.6 28.9 56.9 76.0 118.1 61.6 48.2 31.0 22.8 96.0 55.2 33.7 38.5 47.1 51.2 69.9 168.9 52.0 135.7 35.5 13.7 29.9 82.3 39.6 74.2 54.5 65.0 64.4 61.8 26.7 26.1 53.0 36.7 63.2 65.9 82.6 87.1 61.0 35.5 42.1 65.7 48.3 54.9 96.4 128.3 160.2 80.2 62.0 42.7 83.4 81.8 40.1 90.6 106.6 170.3 26.5 42.3 54.2 81.0 66.3 49.0 18.6 32.0 192.7 52.6 99.6 50.5 75.7 64.8 23.0 68.3 60.9 73.7 58.2 51.1 48.3 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MECP2 "MRX16, MRX79, RTT" ENSG00000169057 "Methyl-CpG binding protein 2" P51608 X 154021573-154137103 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 206.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 47.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 47.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000593, HPA001341, CAB037264" Enhanced Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB037264: AB_477252, HPA000593: AB_1079348, HPA001341: AB_1079347" "unprognostic (1.27e-3)" "unprognostic (2.60e-3)" "unprognostic (2.16e-3)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.35e-1)" "unprognostic (3.66e-1)" "unprognostic (6.12e-2)" "unprognostic (1.18e-2)" "unprognostic (8.81e-2)" "unprognostic (1.53e-1)" "unprognostic (1.84e-3)" "unprognostic (4.22e-1)" "prognostic favorable (7.32e-9)" "unprognostic (7.63e-2)" "unprognostic (1.00e-1)" "unprognostic (9.08e-2)" "unprognostic (6.05e-2)" 21.0 17.7 11.2 13.4 12.8 24.9 18.0 19.4 17.1 24.0 6.6 21.8 9.9 19.0 10.8 14.4 21.7 10.8 23.3 12.0 13.4 17.8 16.5 24.6 13.4 13.7 13.7 24.8 14.8 14.7 22.8 8.6 12.7 23.9 5.3 23.0 14.4 15.6 33.5 14.8 16.1 11.5 9.1 23.6 15.4 8.6 13.6 15.6 18.9 14.4 9.1 20.0 19.3 16.9 34.4 19.2 15.9 18.6 13.1 8.8 12.7 17.0 14.6 14.9 25.2 14.1 13.3 37.4 39.5 13.3 28.9 16.0 19.3 15.9 8.8 32.5 27.8 13.6 17.6 9.4 14.9 18.2 28.2 8.7 10.0 15.6 13.2 15.4 12.9 17.5 17.3 28.9 11.1 17.9 23.1 21.8 11.2 21.9 19.9 20.0 16.2 13.2 9.2 13.3 21.9 13.6 13.0 14.1 31.6 7.7 8.8 24.8 18.0 14.5 28.8 29.2 35.6 41.0 32.6 41.7 19.6 33.2 25.1 47.8 4.7 19.5 9.1 4.7 6.2 7.8 6.1 7.2 3.5 6.8 5.8 5.4 22.7 4.4 8.2 6.0 7.2 2.7 11.2 12.8 19.4 17.1 12.0 13.4 13.7 13.7 12.7 9.1 13.6 16.9 53.9 6.4 34.4 26.4 74.7 30.8 43.4 28.3 21.6 88.0 40.7 24.6 41.2 34.3 34.9 46.0 206.4 17.0 130.8 23.9 66.5 39.4 1.4 28.2 34.4 41.0 36.5 48.4 31.7 30.7 17.7 38.5 16.3 22.7 52.6 32.2 66.4 38.1 25.6 99.3 35.3 21.0 52.9 45.5 68.7 3.5 53.4 54.1 30.2 45.0 58.9 39.8 85.5 30.2 45.0 36.2 30.3 73.7 56.1 34.8 36.7 44.5 28.1 92.7 32.9 53.6 57.1 16.0 39.0 18.1 29.0 18.5 93.6 25.6 17.3 36.4 MED1 "CRSP1, CRSP200, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2" ENSG00000125686 "Mediator complex subunit 1" Q15648 17 39404285-39451272 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 206.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017696, HPA052818" Approved Supported Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB017696: AB_1128703, HPA052818: AB_2681962" "unprognostic (1.77e-1)" "unprognostic (1.63e-1)" "unprognostic (9.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.50e-1)" "unprognostic (7.86e-2)" "unprognostic (1.95e-3)" "unprognostic (4.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.78e-2)" "unprognostic (2.00e-1)" "unprognostic (5.94e-2)" "unprognostic (9.40e-2)" "unprognostic (5.79e-2)" 10.3 8.7 7.2 11.3 7.7 12.9 10.6 8.5 8.2 9.7 7.4 10.6 7.7 11.0 5.9 9.8 9.3 7.6 9.6 6.9 7.4 8.8 9.0 8.7 13.3 7.2 7.3 11.3 7.9 16.8 6.0 10.4 7.5 8.3 9.5 8.0 8.6 7.7 13.7 11.1 9.7 11.2 7.4 11.2 8.6 10.7 7.7 16.9 9.1 12.2 14.7 10.9 9.1 8.8 20.1 24.5 32.5 22.7 23.1 23.7 25.8 24.0 25.6 30.6 30.1 24.9 20.1 51.4 26.2 28.9 37.2 38.3 38.0 22.9 50.0 49.2 31.8 32.3 24.1 24.0 24.4 59.8 33.9 22.1 23.6 39.3 55.0 20.1 28.1 30.6 42.1 28.4 25.7 10.7 56.5 23.2 20.9 19.4 15.1 41.3 43.1 22.9 18.5 22.4 20.3 23.2 30.9 206.2 27.6 28.0 38.5 33.4 23.7 24.8 31.1 28.1 42.3 25.3 36.4 53.6 24.3 28.4 32.0 1.3 1.4 1.8 1.6 1.4 1.9 2.2 1.8 1.8 1.5 2.0 1.8 2.1 1.2 1.9 0.8 1.5 1.5 1.0 7.2 7.7 8.5 8.2 6.9 7.4 7.2 7.3 7.5 7.4 7.7 8.8 18.8 25.6 13.9 10.1 24.7 27.1 14.2 13.1 19.4 13.7 18.0 13.8 18.9 12.8 21.0 9.2 14.6 17.2 20.6 12.7 3.9 12.3 7.9 19.0 27.1 21.2 13.8 26.9 13.4 12.0 12.8 19.7 10.7 27.0 9.5 19.9 17.2 20.2 14.9 11.8 13.9 14.8 16.2 20.0 16.5 7.7 14.6 16.4 21.4 11.2 21.0 13.5 17.5 11.1 16.0 13.7 12.1 18.0 20.2 19.9 9.4 8.5 17.4 12.0 19.7 26.1 21.2 22.3 17.0 21.7 32.7 22.2 22.8 18.7 15.0 18.7 MED12 "ARC240, CAGH45, FGS1, HOPA, KIAA0192, Kto, OKS, OPA1, TNRC11, TRAP230" ENSG00000184634 "Mediator complex subunit 12" Q93074 X 71118556-71142454 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003184, HPA003185" Enhanced Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA003184: AB_1079349, HPA003185: AB_1079350" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (5.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.89e-3)" "unprognostic (7.14e-2)" "unprognostic (1.68e-2)" "unprognostic (1.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.22e-3)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-1)" "unprognostic (5.16e-2)" 18.9 32.3 10.1 13.4 11.6 15.1 19.3 10.8 12.2 20.3 9.3 15.2 8.1 18.1 10.7 13.4 17.8 8.5 13.4 9.7 10.5 13.1 10.3 15.2 13.6 12.3 10.9 28.9 14.9 14.1 16.3 16.8 11.3 17.4 9.2 8.2 14.3 12.6 15.4 14.7 15.9 12.6 10.2 28.4 15.5 13.4 11.2 19.1 18.1 10.6 12.2 15.2 17.1 12.0 14.2 16.4 25.5 15.3 18.3 16.1 37.1 9.9 14.0 15.2 10.8 19.8 13.1 18.5 12.7 17.2 10.5 13.8 29.7 12.3 12.1 19.6 23.0 30.7 37.9 27.5 14.3 28.8 26.2 18.9 13.2 20.0 23.3 19.6 23.8 23.1 29.0 31.6 15.2 24.3 30.5 16.3 14.7 18.2 21.3 28.0 28.5 14.0 11.8 27.5 14.0 16.9 22.7 11.8 12.2 26.2 13.9 14.2 21.1 16.5 19.7 15.4 7.0 15.4 9.5 13.7 9.8 15.8 11.2 6.9 2.1 4.3 3.0 1.9 2.5 2.0 2.1 2.8 2.1 1.9 2.3 2.0 4.1 2.7 1.3 2.8 4.4 2.4 10.1 11.6 10.8 12.2 9.7 10.5 12.3 10.9 11.3 10.2 11.2 12.0 15.4 9.6 4.2 7.2 8.4 6.0 6.3 6.5 4.6 7.2 8.6 11.0 9.3 11.5 7.6 9.2 6.2 20.7 10.9 10.8 1.9 6.9 0.4 7.9 8.9 12.8 7.8 13.7 3.8 6.3 8.0 8.2 8.6 7.1 9.5 21.1 14.6 4.4 9.1 13.5 4.2 5.8 2.0 6.5 9.8 2.3 14.0 8.9 5.4 6.5 7.4 6.3 13.4 4.0 4.2 9.4 10.0 13.5 7.3 7.5 7.5 2.7 7.5 4.9 0.0 10.0 7.6 6.6 7.3 6.1 5.7 27.2 8.8 27.9 6.8 8.6 MED13 "KIAA0593, THRAP1, TRAP240" ENSG00000108510 "Mediator complex subunit 13" Q9UHV7 17 61942605-62065278 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067939 Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA067939: AB_2685928" "unprognostic (7.26e-2)" "unprognostic (4.50e-2)" "prognostic favorable (1.43e-4)" "unprognostic (8.79e-2)" "unprognostic (1.69e-2)" "unprognostic (3.56e-1)" "unprognostic (1.33e-1)" "unprognostic (5.69e-2)" "unprognostic (1.18e-1)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (3.92e-2)" "unprognostic (2.63e-2)" "unprognostic (2.53e-1)" "unprognostic (1.21e-1)" "unprognostic (4.51e-3)" "unprognostic (2.30e-1)" 12.4 9.6 7.9 10.7 12.4 34.1 11.2 16.4 9.6 12.3 11.3 12.5 11.5 11.8 8.8 11.2 9.3 12.7 8.8 9.2 6.9 13.6 22.1 10.9 12.7 9.5 9.8 13.5 12.5 17.6 5.5 15.3 10.6 10.2 12.7 17.8 10.0 8.9 19.4 11.4 10.6 11.9 8.0 11.5 12.2 19.5 10.2 20.7 15.9 28.1 12.7 13.3 8.4 15.3 24.9 29.0 22.0 18.0 19.8 21.4 16.7 13.4 19.4 26.5 25.5 22.2 13.2 26.4 12.3 21.2 19.9 15.0 28.2 17.5 36.9 17.2 16.6 43.1 20.9 14.3 20.7 38.1 19.3 16.6 19.8 29.0 32.8 19.1 20.3 20.4 35.8 43.9 18.3 41.8 34.6 11.4 11.7 28.9 14.8 28.1 56.2 16.2 18.6 28.8 17.3 32.6 28.0 8.0 17.5 21.7 28.8 26.7 25.6 30.2 44.3 15.9 25.6 21.2 25.8 35.4 16.0 16.7 17.6 1.1 1.1 1.3 1.3 0.5 1.6 1.0 1.3 1.4 1.1 1.5 0.9 1.6 4.0 1.4 2.9 2.8 1.6 0.4 7.9 12.4 16.4 9.6 9.2 6.9 9.5 9.8 10.6 8.0 10.2 15.3 54.7 64.1 54.0 107.7 37.7 78.0 45.9 23.6 45.5 52.3 45.8 28.1 27.8 52.9 36.6 23.9 45.9 19.1 57.2 57.9 9.8 16.7 47.4 48.1 63.7 42.0 44.3 42.3 96.9 20.0 11.7 45.2 35.7 83.3 26.0 42.0 35.3 45.5 19.1 62.2 107.3 41.7 32.6 30.5 78.6 60.1 30.7 52.0 32.0 89.0 36.7 36.5 24.7 135.2 136.7 28.6 38.4 32.7 41.1 62.6 33.4 19.1 29.9 40.3 32.9 81.6 45.9 48.1 22.6 48.0 81.7 43.4 40.7 32.3 32.9 81.0 MED17 "CRSP6, CRSP77, DRIP80, SRB4, TRAP80" ENSG00000042429 "Mediator complex subunit 17" Q9NVC6 11 93784227-93814963 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 2.3;cerebral cortex: 1.3;white matter: 1.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046619 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA046619: " "prognostic unfavorable (4.94e-4)" "unprognostic (2.92e-1)" "unprognostic (2.72e-3)" "unprognostic (1.38e-1)" "unprognostic (6.71e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.48e-3)" "unprognostic (7.73e-2)" "unprognostic (1.41e-1)" "unprognostic (4.59e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-1)" "unprognostic (2.22e-1)" "unprognostic (5.56e-3)" "unprognostic (1.48e-1)" 1.3 0.9 0.2 1.5 0.4 1.5 1.0 2.3 1.3 1.4 1.2 1.5 0.4 1.8 1.0 1.0 1.5 0.6 1.7 0.3 0.2 0.9 0.5 1.1 1.1 0.4 0.2 1.6 1.4 0.5 0.8 1.3 0.3 1.0 0.5 1.1 1.0 0.7 1.6 1.1 2.1 1.0 0.1 2.3 1.7 0.9 0.4 1.3 0.9 1.1 1.0 1.0 1.0 1.7 3.3 1.1 2.7 5.9 3.3 0.4 5.3 7.3 2.5 4.7 2.8 5.9 6.6 5.3 11.6 0.6 1.3 9.8 2.5 1.4 1.3 6.5 2.9 6.0 3.7 1.7 1.7 10.5 10.1 1.3 3.4 3.5 2.1 1.1 1.9 1.4 5.5 3.4 2.7 1.0 12.3 3.1 5.1 0.7 0.8 9.5 7.8 4.4 2.8 2.3 9.7 12.3 5.8 4.7 2.8 0.6 7.2 2.5 6.5 7.2 5.7 9.9 6.3 4.9 10.1 3.9 1.9 7.2 8.5 3.3 3.0 7.6 4.0 3.7 4.5 8.2 5.1 5.0 3.8 5.8 5.2 2.9 3.3 6.7 2.2 4.5 5.3 3.5 0.2 0.4 2.3 1.3 0.3 0.2 0.4 0.2 0.3 0.1 0.4 1.7 7.7 6.4 9.3 16.3 32.1 30.1 39.6 19.4 25.6 24.6 10.1 4.6 15.5 14.3 19.5 7.3 16.7 39.3 25.5 12.4 1.9 15.8 1.0 9.3 14.9 14.2 26.8 9.7 25.8 9.7 27.4 17.2 17.3 13.6 10.8 22.9 16.8 8.6 14.5 15.2 27.7 13.4 16.2 15.5 27.0 3.0 15.8 12.8 14.2 19.7 18.4 13.4 23.7 22.1 25.1 10.4 14.8 21.4 25.6 26.9 13.8 2.7 19.4 43.9 65.7 19.3 16.4 23.1 16.3 18.1 25.7 34.1 28.1 10.4 17.6 36.3 MED23 "CRSP130, CRSP3, DRIP130, MRT18, Sur2" ENSG00000112282 "Mediator complex subunit 23" Q9ULK4 6 131573966-131628242 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 72.0;Inhibitory neurons: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070341 Approved Nucleoplasm,Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA070341: AB_2686257" "unprognostic (1.11e-2)" "unprognostic (4.66e-2)" "unprognostic (5.51e-3)" "unprognostic (1.80e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (6.62e-3)" "unprognostic (4.47e-1)" "unprognostic (1.64e-1)" "unprognostic (6.81e-3)" "unprognostic (1.44e-2)" "unprognostic (3.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.82e-2)" "unprognostic (2.21e-1)" "unprognostic (2.44e-2)" "unprognostic (2.53e-2)" 7.7 10.5 3.4 11.5 3.7 22.0 14.3 9.8 5.0 12.0 3.7 10.6 11.4 13.3 10.6 8.5 11.0 8.9 6.5 3.5 3.6 10.3 7.9 9.9 14.8 2.4 2.8 14.2 10.7 18.3 6.0 11.0 3.1 11.7 12.4 11.5 12.7 11.6 7.4 11.5 10.6 10.4 2.7 12.8 11.6 10.5 3.5 18.0 14.4 10.1 15.3 10.1 7.8 6.4 7.2 7.8 18.2 23.0 22.1 16.8 16.7 17.6 19.8 16.0 23.0 8.2 9.8 15.9 12.5 18.2 15.4 12.6 9.9 11.4 24.7 18.1 13.8 16.6 14.9 14.0 16.0 27.8 27.1 14.9 13.3 17.7 17.8 18.6 20.1 16.9 21.7 16.2 17.0 11.0 21.3 17.4 8.7 12.3 7.8 18.9 11.4 9.6 12.2 10.4 13.6 12.3 12.6 17.4 11.6 20.9 4.8 19.3 20.4 11.8 13.3 19.0 16.2 17.0 12.3 22.6 14.5 12.6 16.1 4.9 4.5 7.6 5.5 4.6 8.3 4.7 5.5 6.2 5.6 4.2 5.5 5.1 3.6 12.9 3.3 2.9 6.6 3.9 3.4 3.7 9.8 5.0 3.5 3.6 2.4 2.8 3.1 2.7 3.5 6.4 16.3 19.2 9.6 24.8 21.5 9.2 6.3 11.9 13.6 23.7 15.5 10.9 6.5 8.6 15.7 23.9 16.7 8.7 23.7 15.5 3.9 7.6 2.1 14.8 14.7 13.9 14.4 12.0 72.0 7.7 6.8 12.5 14.3 16.6 14.0 18.3 14.3 12.4 8.1 11.8 67.1 17.4 6.1 17.6 9.5 3.2 14.3 12.8 5.4 36.5 16.9 7.7 21.6 42.3 60.8 9.1 14.9 10.1 19.4 10.7 14.7 8.5 13.4 24.4 13.1 13.8 10.2 13.5 5.3 12.0 8.7 7.8 20.7 14.6 14.3 12.8 MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716466 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 262.8;Microglial cells: 708.3;Oligodendrocytes: 264.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004499, HPA046597" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004499: AB_627921, HPA046597: AB_2679714" "unprognostic (1.89e-1)" "unprognostic (8.82e-2)" "unprognostic (5.91e-2)" "unprognostic (8.04e-2)" "unprognostic (8.68e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.93e-2)" "unprognostic (1.91e-2)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "prognostic favorable (6.93e-4)" "prognostic unfavorable (7.96e-4)" "unprognostic (4.69e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-3)" 32.8 22.9 18.7 20.3 25.4 18.3 22.1 16.4 27.6 27.7 12.9 23.5 12.8 34.5 23.8 21.7 21.8 22.6 89.7 21.9 12.1 24.8 24.5 30.4 25.0 17.4 20.7 30.1 12.8 37.6 9.8 26.4 15.4 23.0 15.0 24.2 19.5 23.7 61.5 54.8 17.6 35.7 18.4 27.2 17.8 15.0 28.4 23.3 19.7 81.9 22.9 22.5 16.6 25.7 17.9 10.1 16.7 8.5 20.7 26.3 8.2 17.8 40.8 14.4 19.5 10.4 24.4 22.3 24.5 38.6 22.1 19.3 17.1 14.1 18.6 15.3 24.8 45.2 22.3 9.4 35.4 18.1 21.3 17.6 23.2 19.3 39.7 59.6 26.5 18.3 16.3 41.6 27.0 7.4 29.7 26.3 8.9 11.9 14.6 43.3 36.1 18.5 29.5 24.9 10.7 14.8 27.2 11.6 51.0 17.6 11.0 16.4 43.7 39.8 21.9 19.9 21.7 22.6 27.8 48.5 27.8 19.6 38.7 7.7 12.1 14.3 3.9 15.6 3.3 15.8 3.6 3.6 13.3 12.1 5.0 3.9 10.8 6.5 19.3 7.8 2.6 5.6 18.7 25.4 16.4 27.6 21.9 12.1 17.4 20.7 15.4 18.4 28.4 25.7 152.7 80.1 43.9 113.9 87.2 88.6 31.7 26.9 62.0 52.0 31.6 37.0 175.8 20.0 40.7 29.5 50.1 7.7 32.9 26.5 25.4 18.0 10.4 80.3 60.6 100.6 12.7 24.8 262.8 18.8 3.4 61.5 34.7 130.7 31.0 30.5 50.3 41.0 39.5 30.3 174.9 17.2 12.2 107.5 63.1 7.8 55.9 104.1 35.6 708.3 65.8 25.2 23.7 157.3 264.4 26.8 22.6 64.7 55.6 27.0 18.9 19.7 51.7 44.9 72.3 62.4 69.4 29.9 29.6 29.4 50.4 9.2 27.8 28.8 17.9 26.8 MEN1 ENSG00000133895 "Menin 1" O00255 11 64803510-64811294 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030342 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA030342: AB_10610138" "unprognostic (2.06e-1)" "unprognostic (1.76e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.66e-1)" "unprognostic (2.59e-1)" "unprognostic (1.42e-2)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (7.39e-2)" "prognostic favorable (6.31e-5)" "unprognostic (1.40e-1)" "unprognostic (3.03e-1)" "unprognostic (3.76e-1)" 15.1 24.2 13.1 8.4 13.7 6.5 15.7 12.7 15.0 19.3 13.0 16.8 7.8 17.4 8.1 23.9 16.3 5.5 12.4 14.3 12.7 19.4 30.3 16.1 10.9 12.5 12.5 20.8 26.2 6.3 21.7 7.8 12.6 20.2 4.7 4.7 21.3 7.7 11.0 24.0 20.9 5.3 11.9 25.5 20.6 16.3 13.5 17.1 24.5 5.8 10.2 16.4 18.7 12.9 30.8 33.7 22.4 37.7 30.4 17.4 24.8 19.2 23.3 35.6 21.2 19.0 25.5 43.6 33.8 16.7 29.8 39.0 36.4 28.3 19.3 30.5 48.1 35.6 17.3 30.9 27.2 23.6 22.8 19.2 18.2 26.8 21.9 16.5 33.7 49.3 51.5 15.7 18.9 54.2 60.3 29.3 36.7 30.3 54.7 45.1 29.8 44.1 23.2 22.8 33.6 28.9 26.0 36.9 27.9 16.5 56.6 27.1 17.4 23.5 28.8 36.5 16.7 21.8 30.4 22.1 25.5 16.2 21.0 0.5 0.5 1.4 1.5 0.6 1.8 1.8 1.1 1.9 0.6 1.8 1.9 0.9 0.1 0.9 0.2 1.3 0.9 0.5 13.1 13.7 12.7 15.0 14.3 12.7 12.5 12.5 12.6 11.9 13.5 12.9 6.9 3.2 5.4 5.9 10.6 5.7 4.6 5.3 7.4 8.5 10.2 11.0 4.5 4.3 2.8 3.7 6.2 19.4 8.0 9.2 3.9 8.9 0.9 7.9 11.0 7.0 4.2 10.8 7.4 7.1 21.7 6.9 13.7 12.1 1.3 14.1 7.9 10.9 9.0 3.3 6.2 9.0 6.1 3.1 2.3 0.9 12.2 4.8 8.8 8.4 6.3 7.7 6.2 4.5 5.0 7.5 10.7 3.8 8.4 6.1 9.3 8.0 4.0 6.5 13.1 5.4 5.6 14.2 13.0 9.4 7.0 16.3 8.9 14.3 10.2 3.3 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 203.8;CAPAN-2: 219.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 100000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 10.3 0.8 0.1 3.4 0.6 7.4 8.9 0.1 7.5 13.1 9.6 9.7 6.5 6.4 2.5 6.1 4.7 11.9 6.2 6.6 0.8 20.1 42.9 20.3 2.3 1.1 2.5 0.8 6.6 0.8 3.8 26.4 4.9 6.7 9.3 3.9 8.7 11.2 14.3 7.7 8.2 5.7 0.3 6.0 15.4 0.5 0.5 3.7 17.6 11.0 3.2 18.4 4.4 7.8 203.8 115.3 0.1 0.6 8.6 8.7 7.9 113.7 48.2 60.3 51.1 25.0 219.0 8.4 179.0 72.1 163.3 51.8 19.7 110.0 123.7 0.3 23.4 0.1 112.5 21.4 1.5 0.3 0.2 11.4 42.4 40.6 129.1 109.4 42.4 0.2 4.5 0.8 114.1 5.0 0.1 0.1 17.3 32.9 113.0 0.2 95.3 0.2 105.8 24.0 16.5 0.0 45.4 15.4 44.9 19.8 0.4 0.9 72.3 89.7 30.6 46.7 88.9 2.5 19.1 1.5 99.3 0.3 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 7.5 6.6 0.8 1.1 2.5 4.9 0.3 0.5 7.8 32.6 28.9 103.6 0.3 1.0 39.0 70.5 58.1 38.1 6.7 6.5 6.9 12.3 11.5 99.8 31.3 0.0 76.0 0.4 20.5 0.0 38.5 0.0 52.5 11.6 20.1 7.2 0.0 2.6 46.9 7.5 7.4 32.6 161.4 0.0 0.0 3.9 30.5 7.0 0.0 1.0 20.5 18.3 1.3 2.2 0.1 0.6 4.4 3.6 1.9 1.0 7.6 0.0 0.5 7.7 93.9 5.5 0.0 0.4 149.3 11.2 15.6 34.5 0.3 0.0 37.8 5.2 0.0 0.6 7.9 17.8 21.8 1.2 0.0 16.4 128.6 METTL14 KIAA1627 ENSG00000145388 "Methyltransferase like 14" Q9HCE5 4 118685392-118715433 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038002 Supported Supported Nucleoplasm Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA038002: AB_10672401" "unprognostic (4.48e-1)" "unprognostic (5.13e-2)" "unprognostic (5.98e-3)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.83e-1)" "unprognostic (3.75e-2)" "unprognostic (4.40e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-2)" "unprognostic (3.64e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (1.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.76e-3)" "unprognostic (7.76e-3)" 8.9 8.8 5.2 8.6 6.0 19.5 11.5 6.8 6.3 8.8 5.5 8.8 8.8 11.7 10.7 8.9 8.8 7.7 8.3 4.8 6.3 10.2 14.9 9.1 11.6 5.5 5.2 12.7 7.8 10.9 8.2 9.0 6.3 9.7 8.2 11.7 7.6 8.0 8.4 10.9 9.2 9.2 5.4 10.8 7.9 15.1 5.7 12.5 10.6 7.7 11.0 8.5 7.9 7.4 19.6 8.9 19.0 17.8 11.7 14.7 13.8 17.1 13.0 12.6 14.4 12.9 22.8 22.0 9.8 12.0 12.6 9.4 16.2 14.1 16.1 17.5 9.8 18.5 11.4 14.4 13.3 30.2 21.2 13.1 15.8 14.6 9.6 16.5 11.5 17.4 20.1 18.2 17.5 13.2 29.7 24.7 16.2 16.7 7.7 16.8 23.7 11.2 13.8 12.7 15.4 17.3 12.0 22.0 17.2 17.2 10.0 28.5 15.8 18.1 16.6 16.3 13.7 15.2 17.0 24.9 12.9 16.5 15.1 37.7 12.8 29.0 17.0 19.6 19.3 24.3 17.8 17.7 15.3 25.3 21.0 19.0 10.3 21.8 23.7 12.1 20.8 13.7 5.2 6.0 6.8 6.3 4.8 6.3 5.5 5.2 6.3 5.4 5.7 7.4 18.6 25.6 25.9 14.7 20.6 10.8 18.3 10.6 16.5 16.8 13.4 12.6 15.7 17.2 20.8 23.9 22.9 18.7 28.3 13.7 11.7 11.9 96.9 14.5 21.7 17.3 12.1 8.4 18.7 15.6 10.2 16.8 9.2 18.0 22.1 18.3 16.4 32.1 12.1 8.4 17.0 15.2 6.1 17.9 7.6 16.7 18.6 13.3 7.2 14.0 14.0 13.4 25.7 14.1 26.9 14.8 13.0 13.9 8.2 17.1 15.4 20.6 15.2 25.4 13.1 15.3 15.5 42.2 28.1 12.4 11.9 15.3 20.6 17.0 12.8 16.0 MFGE8 "BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10" ENSG00000140545 "Milk fat globule EGF and factor V/VIII domain containing" Q08431 15 88898683-88913381 "Cancer-related genes, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 407.0;Cone photoreceptor cells: 385.7;Rod photoreceptor cells: 978.7;Sertoli cells: 1084.7;Smooth muscle cells: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.9" "Group enriched" "Detected in many" 8 "granulocytes: 5.3;NK-cells: 7.7;T-cells: 14.9" "Cell line enhanced" "Detected in many" "ASC diff: 1784.6;ASC TERT1: 918.2;fHDF/TERT166: 660.4;HSkMC: 935.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002753, HPA002807" Enhanced Approved Cytosol "Secreted to blood" NA NA 2830000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "CAB002753: , HPA002807: AB_1078072" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (7.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.11e-3)" "unprognostic (6.27e-2)" "unprognostic (8.49e-2)" "unprognostic (3.99e-1)" "prognostic unfavorable (6.06e-9)" "prognostic unfavorable (3.08e-4)" "unprognostic (4.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.41e-3)" 237.2 95.2 44.2 45.2 49.6 3.7 226.7 56.4 61.8 272.8 52.4 113.7 21.2 444.7 77.0 67.6 361.8 120.2 485.8 41.6 47.2 69.0 15.6 137.2 47.4 55.9 47.4 228.5 36.5 18.9 49.3 79.6 55.6 129.3 29.3 68.7 97.1 195.8 264.3 118.9 106.9 162.7 47.0 40.7 124.9 38.3 46.5 18.8 90.6 124.1 36.9 163.6 223.4 55.6 19.7 85.4 78.7 98.7 1784.6 918.2 6.9 482.7 142.4 95.4 110.3 90.5 23.5 0.0 147.5 660.4 144.6 10.2 27.6 95.8 31.1 82.3 64.7 138.1 4.6 10.2 469.8 0.2 50.1 935.7 251.8 73.5 122.5 205.3 37.0 35.3 23.4 41.1 185.1 6.2 22.6 3.2 405.4 8.3 38.4 22.7 74.4 26.4 32.6 7.3 8.2 42.9 28.0 2.5 226.1 165.6 2.4 11.1 42.0 233.2 127.8 62.3 36.3 145.3 30.5 15.9 31.6 12.2 91.5 5.3 0.2 0.4 1.3 0.0 4.2 1.2 4.2 2.9 0.0 0.9 4.3 3.3 0.0 7.7 0.1 0.1 14.9 2.1 44.2 49.6 56.4 61.8 41.6 47.2 55.9 47.4 55.6 47.0 46.5 55.6 72.1 12.8 5.4 39.2 4.0 48.7 32.2 116.3 24.5 22.1 407.0 190.4 92.8 8.6 25.5 3.7 385.7 4.5 13.1 1.6 0.0 15.7 11.0 33.3 202.2 66.9 44.8 3.8 5.1 4.3 18.6 220.0 12.8 29.7 5.1 30.1 22.1 15.5 8.1 16.8 0.4 6.4 36.7 32.9 39.7 27.9 187.0 12.9 119.2 15.0 1.8 75.9 9.2 5.5 9.6 28.3 0.2 109.1 8.8 15.8 0.1 0.2 8.3 978.7 1084.7 51.8 476.0 3.3 9.0 21.7 35.9 5.3 12.5 25.8 2.0 10.2 MGA "FLJ12634, KIAA0518, MAD5, MXD5" ENSG00000174197 "MAX dimerization protein MGA" Q8IWI9 15 41621224-41773081 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042278, HPA058183" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA042278: AB_10794647, HPA058183: AB_2683632" "unprognostic (5.78e-2)" "unprognostic (7.97e-2)" "unprognostic (2.97e-1)" "unprognostic (7.20e-2)" "unprognostic (6.26e-3)" "unprognostic (5.82e-3)" "unprognostic (8.61e-3)" "unprognostic (1.70e-1)" "unprognostic (1.90e-2)" "unprognostic (3.96e-3)" "unprognostic (3.71e-1)" "unprognostic (3.80e-2)" "unprognostic (1.43e-2)" "unprognostic (1.57e-1)" "unprognostic (3.93e-1)" "unprognostic (2.50e-1)" "unprognostic (3.89e-1)" 3.9 5.2 7.0 5.4 12.1 8.7 7.2 33.6 8.5 7.3 0.0 4.5 3.7 7.4 6.0 4.5 5.8 4.2 4.5 4.9 11.6 5.2 4.6 4.3 7.6 6.4 6.9 12.0 5.0 6.0 3.9 6.9 8.8 5.7 5.1 7.0 5.1 5.5 5.1 6.2 3.9 5.7 3.8 6.8 4.6 8.7 8.6 11.6 7.5 7.8 7.6 5.4 3.9 17.3 2.4 13.5 16.6 10.9 12.8 10.1 13.3 6.7 6.8 7.8 7.7 14.5 7.8 16.2 11.8 7.8 14.2 9.3 25.9 5.9 10.7 7.7 8.5 34.3 22.1 12.8 11.3 31.9 16.4 7.7 7.2 10.9 10.7 3.2 10.3 15.5 40.7 7.2 7.1 6.7 19.4 12.3 10.3 7.0 6.9 21.7 16.9 8.5 4.1 9.8 15.7 15.3 24.0 8.2 4.3 12.1 6.6 20.1 11.0 9.5 13.3 9.8 8.0 9.8 15.7 15.3 6.0 11.9 4.8 3.6 1.4 1.6 2.5 1.0 2.5 2.8 2.1 2.9 1.4 3.0 2.1 2.4 0.6 5.8 3.3 2.4 1.1 1.0 7.0 12.1 33.6 8.5 4.9 11.6 6.4 6.9 8.8 3.8 8.6 17.3 18.5 22.4 19.8 56.5 28.1 7.9 10.9 7.2 13.6 25.5 11.1 8.9 29.5 5.7 16.2 12.9 33.3 18.1 23.6 9.7 7.9 11.8 16.7 16.8 35.4 18.6 7.8 28.6 62.4 5.3 12.0 20.5 18.8 24.9 14.5 32.9 15.0 9.3 11.8 13.5 60.1 10.0 8.2 11.9 8.8 7.0 20.8 17.1 8.8 44.0 13.2 16.0 25.7 64.8 122.6 8.1 13.5 20.7 16.4 16.2 7.6 5.2 14.9 23.6 39.5 35.6 19.2 45.4 40.4 11.7 11.2 26.0 27.5 23.5 11.3 10.7 MGMT ENSG00000170430 "O-6-methylguanine-DNA methyltransferase" P16455 10 129467190-129770983 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 465.7;Proximal tubular cells: 340.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 60.0" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002786, HPA032135, HPA032136, HPA069497, CAB069881" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "CAB002786: , CAB069881: AB_10002128, HPA032135: AB_2674171, HPA032136: AB_2674172, HPA069497: AB_2732134" "unprognostic (1.10e-1)" "prognostic favorable (9.42e-4)" "unprognostic (1.48e-1)" "unprognostic (5.81e-2)" "unprognostic (7.84e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-4)" "unprognostic (6.54e-3)" "unprognostic (4.71e-2)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (6.32e-1)" "unprognostic (4.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" 21.5 17.0 14.7 10.3 15.1 12.7 20.4 14.8 18.6 13.9 16.6 14.7 16.9 13.3 8.1 15.9 23.7 19.6 18.5 14.1 14.5 23.5 89.3 11.7 19.4 15.9 15.4 16.9 26.5 12.3 9.5 6.8 16.0 15.0 5.0 3.9 22.7 7.8 25.5 17.1 15.3 8.0 14.7 14.3 18.2 15.2 15.0 23.2 16.3 16.0 11.1 18.4 13.8 15.2 0.0 7.0 7.1 35.2 14.9 30.9 27.1 15.6 17.0 10.9 10.7 44.0 45.6 33.0 24.6 20.2 0.0 20.8 4.5 16.4 4.6 0.0 2.7 6.6 16.2 28.6 22.7 0.7 17.8 19.7 0.0 6.6 0.0 0.0 0.1 53.5 0.1 22.0 14.0 60.0 26.1 34.0 1.6 29.9 27.8 29.3 0.1 12.7 20.7 16.0 7.2 18.0 18.3 7.7 0.0 5.5 29.8 25.3 0.0 14.6 7.1 0.1 0.0 0.0 0.0 17.1 0.0 10.8 0.0 9.6 37.2 17.1 43.9 39.2 43.6 49.7 40.4 42.0 39.0 48.2 39.6 42.8 4.6 49.5 37.2 43.7 54.0 42.1 14.7 15.1 14.8 18.6 14.1 14.5 15.9 15.4 16.0 14.7 15.0 15.2 106.0 12.8 19.0 32.0 59.2 51.2 80.6 91.5 49.5 17.4 69.0 112.9 49.3 94.4 48.7 103.0 8.4 51.3 51.1 55.6 127.2 50.0 107.6 138.0 29.6 70.4 54.5 48.2 28.5 58.7 67.0 59.2 31.1 34.1 64.7 93.9 108.1 465.7 89.7 15.2 16.9 73.1 50.8 75.0 48.7 140.6 67.4 44.6 65.8 62.8 56.4 37.2 78.2 23.1 30.7 82.4 57.9 55.3 37.0 47.1 108.4 340.3 102.5 45.6 46.0 48.6 70.6 45.3 81.4 46.9 42.6 26.8 52.5 87.4 63.8 75.2 MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 57.9;pituitary gland: 76.2;salivary gland: 43.3;stomach 1: 65.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 51.4;Breast myoepithelial cells: 171.7;Melanocytes: 103.2;monocytes: 30.0;Pancreatic endocrine cells: 66.8;Respiratory ciliated cells: 53.9" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Group enriched" "Detected in some" 29 "AN3-CA: 90.1;CAPAN-2: 80.6;SK-MEL-30: 271.9;WM-115: 247.7" HPA042369 Approved "Secreted to blood" NA NA 8270000 64000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 4: Stomach - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA042369: AB_10794420" "prognostic favorable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" 2.6 2.9 4.9 6.9 5.9 2.9 57.9 5.7 7.5 8.3 5.4 16.9 2.0 1.2 2.0 6.6 3.7 2.9 5.3 4.4 4.8 2.4 2.7 1.9 2.0 5.3 5.0 7.0 1.4 0.0 76.2 2.1 5.6 6.4 4.2 0.4 43.3 3.3 0.7 9.6 5.9 7.6 4.8 7.0 65.8 1.7 5.5 2.4 2.9 1.7 1.6 4.0 5.2 7.9 0.3 0.9 1.5 90.1 1.3 1.2 1.0 0.0 0.0 0.0 0.5 0.5 80.6 0.2 0.0 0.0 0.3 0.2 0.4 4.9 0.1 2.9 0.9 0.0 1.0 0.1 0.4 0.2 0.4 0.7 4.2 0.0 1.5 1.4 0.0 1.4 0.0 0.9 0.0 0.0 0.1 0.0 0.2 5.9 0.3 0.1 0.2 0.0 2.5 0.0 0.2 0.1 0.1 0.0 271.9 3.4 0.5 1.2 0.0 0.2 3.4 0.1 1.0 0.0 0.2 0.9 0.1 0.4 247.7 0.6 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 4.9 5.9 5.7 7.5 4.4 4.8 5.3 5.0 5.6 4.8 5.5 7.9 1.0 0.0 0.5 0.0 0.3 5.2 0.1 11.2 0.6 0.0 51.4 171.7 0.6 0.0 4.9 0.0 0.0 0.8 0.5 1.7 0.0 0.5 0.0 0.9 0.0 1.4 0.0 0.0 0.0 3.2 0.1 1.1 14.3 0.2 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.1 4.1 0.0 0.7 0.3 0.6 0.2 103.2 0.0 30.0 0.0 0.0 0.0 0.0 66.8 5.1 0.0 0.1 0.8 0.4 0.0 53.9 0.0 0.0 0.2 1.3 0.1 0.6 6.1 1.3 0.7 0.3 0.8 4.1 0.5 MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894383-23895227 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 2032.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 4974.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003868, CAB005284" Approved Enhanced Nucleoplasm,Cytosol "Secreted to blood" No No 13800000 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "CAB005284: AB_648587, HPA003868: AB_1079290" "unprognostic (1.68e-1)" "unprognostic (7.79e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (9.48e-2)" "unprognostic (1.22e-3)" "unprognostic (2.17e-2)" "unprognostic (1.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" 233.3 467.9 195.8 119.5 200.0 146.0 223.3 209.3 450.0 235.0 204.3 194.3 98.9 205.3 49.8 514.2 219.4 20.9 290.8 245.2 289.7 530.3 484.6 208.2 61.5 225.2 224.7 223.7 255.7 127.8 368.0 100.4 217.2 318.7 35.2 23.8 233.6 132.8 99.3 302.5 171.7 43.4 250.8 204.5 230.7 113.5 204.2 65.0 274.0 19.5 46.2 255.8 316.7 369.4 1698.3 605.3 122.2 499.0 58.9 111.3 590.7 581.2 154.7 298.9 382.1 526.4 364.4 761.3 499.8 83.1 115.2 788.1 155.0 546.8 51.5 642.2 4974.4 286.2 534.6 1126.5 225.3 1077.2 758.6 230.9 354.9 173.8 103.5 248.8 241.3 589.4 466.9 540.1 122.2 1476.0 827.0 2345.5 532.8 488.6 2365.8 1040.4 127.9 2398.8 294.7 179.6 1080.9 1290.4 380.3 531.9 1374.7 37.6 671.2 442.6 424.7 232.5 1227.9 127.3 9.9 1647.2 732.5 1020.9 967.5 484.6 477.9 484.2 543.5 443.5 872.4 579.5 1250.8 1527.9 1221.7 983.3 796.9 1378.9 1040.4 928.4 166.8 1158.9 383.3 977.1 1258.3 1803.3 195.8 200.0 209.3 450.0 245.2 289.7 225.2 224.7 217.2 250.8 204.2 369.4 161.2 157.0 199.4 21.5 433.4 672.2 295.5 1134.8 1027.2 28.3 856.0 778.2 0.3 479.0 489.1 693.4 2.1 462.7 171.3 317.9 1649.4 859.0 190.5 733.7 485.3 248.5 348.9 455.7 17.1 377.7 885.0 336.2 606.5 844.3 180.3 192.2 261.6 885.2 278.8 21.9 24.1 432.5 697.8 207.7 505.2 153.9 336.1 232.6 773.7 19.7 217.0 59.5 155.5 17.6 52.8 649.9 360.4 302.8 1337.1 269.8 476.8 2032.7 404.6 33.2 138.1 338.1 349.7 21.3 124.2 1511.3 758.8 686.0 386.3 227.6 473.0 256.1 MITF "bHLHe32, MI, WS2, WS2A" ENSG00000187098 "Melanocyte inducing transcription factor" O75030 3 69739464-69968336 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Albinism, Cancer-related genes, Deafness, Disease variant, Microphthalmia, Osteopetrosis, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 133.5;Melanocytes: 585.2;Oligodendrocyte precursor cells: 166.9;Oligodendrocytes: 240.3" "Cancer enriched" "Detected in all" 4 "melanoma: 39.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 5.2;classical monocyte: 9.4;intermediate monocyte: 3.3;myeloid DC: 6.1;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 6 "dendritic cells: 6.1;granulocytes: 5.2;monocytes: 9.4" "Cell line enhanced" "Detected in many" "HMC-1: 89.1;SK-MEL-30: 254.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002578, HPA003259" Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB002578: AB_564111, HPA003259: AB_1079381" "unprognostic (3.29e-1)" "unprognostic (4.26e-2)" "unprognostic (2.98e-2)" "unprognostic (6.04e-2)" "unprognostic (1.03e-1)" "unprognostic (3.25e-1)" "unprognostic (1.04e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-1)" "unprognostic (5.31e-3)" "unprognostic (3.87e-3)" "unprognostic (1.94e-1)" "prognostic favorable (8.35e-10)" "unprognostic (6.37e-2)" "unprognostic (1.08e-1)" "unprognostic (2.04e-1)" "unprognostic (1.73e-1)" 13.8 4.4 5.1 3.8 9.2 1.7 10.0 9.4 6.3 51.3 21.2 18.8 2.8 46.2 4.5 8.9 10.3 16.8 31.1 5.2 9.3 20.0 2.2 9.7 3.4 12.5 9.5 18.7 4.2 16.8 3.8 3.3 10.4 8.4 4.5 1.2 5.1 14.1 50.6 11.0 5.8 46.0 7.0 2.0 9.4 2.3 10.3 2.2 7.6 43.3 1.5 10.6 16.6 13.8 17.2 12.2 1.3 5.1 18.8 0.3 2.0 16.9 9.9 7.8 4.8 6.1 0.8 0.0 4.0 0.3 21.6 8.6 3.7 9.4 8.6 0.0 2.5 37.1 24.5 0.3 4.5 0.8 89.1 15.3 3.9 2.2 8.6 29.1 2.4 0.0 12.3 5.2 5.4 1.2 0.7 1.0 0.7 0.7 8.3 0.1 1.9 7.7 45.2 9.0 0.4 1.9 8.8 3.1 254.1 2.0 0.7 2.3 0.1 3.8 13.3 5.1 3.5 0.6 1.0 0.1 7.7 2.6 9.2 5.2 9.4 0.0 0.0 3.3 0.0 0.0 0.0 0.1 6.1 0.0 0.0 0.0 0.7 1.1 5.9 0.5 0.0 3.1 5.1 9.2 9.4 6.3 5.2 9.3 12.5 9.5 10.4 7.0 10.3 13.8 4.6 28.9 6.8 34.3 0.2 42.8 3.6 16.7 7.4 1.6 1.8 1.8 109.5 11.5 18.2 14.7 0.0 1.3 0.6 0.4 50.9 14.7 1.6 24.5 94.3 7.4 1.2 8.6 14.7 8.8 1.0 38.3 9.7 71.2 106.8 10.9 4.6 2.1 45.8 6.7 133.5 0.3 12.2 30.8 30.9 3.4 44.4 24.3 585.2 50.6 10.6 1.4 0.0 166.9 240.3 7.7 0.0 50.4 0.4 5.2 0.2 24.3 12.5 0.2 13.1 17.8 22.6 4.0 6.3 7.2 18.9 1.1 3.8 5.5 0.6 7.1 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MLF1 ENSG00000178053 "Myeloid leukemia factor 1" P58340 3 158571163-158607252 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Differentiation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 182.3;testis: 393.7" "Group enriched" "Detected in many" 10 "Early spermatids: 4964.0;Late spermatids: 12837.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.7" "Lineage enriched" "Detected in single" 9 "T-cells: 8.7" "Cell line enhanced" "Detected in many" "A-431: 84.0" "Low region specificity" "Detected in all" "HPA069479, HPA079339" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA069479: AB_2686140, HPA079339: " "unprognostic (6.49e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.72e-2)" "unprognostic (2.65e-2)" "unprognostic (8.55e-2)" "unprognostic (4.11e-2)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.21e-2)" "unprognostic (1.07e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (5.54e-4)" "unprognostic (9.34e-3)" "unprognostic (2.47e-3)" "unprognostic (3.36e-2)" 10.9 6.8 16.8 3.0 19.8 3.2 17.4 17.3 22.0 9.8 34.5 10.0 1.8 15.9 14.8 10.2 67.9 15.1 138.9 19.1 19.3 21.2 3.6 17.9 2.9 25.1 25.2 12.8 9.6 20.2 18.1 2.7 24.0 6.2 4.7 46.9 5.1 4.6 182.3 6.2 4.0 14.2 22.0 3.5 6.2 393.7 19.4 2.3 16.5 107.2 4.8 14.1 4.2 24.2 84.0 7.7 28.4 0.1 13.8 18.1 7.8 6.8 8.4 31.9 30.5 0.0 44.8 0.0 29.3 13.1 42.8 16.3 0.3 14.2 44.5 0.0 15.3 3.9 6.3 0.9 10.2 0.0 6.4 10.5 22.3 13.8 8.8 28.2 7.3 0.0 6.3 0.1 22.2 12.5 0.0 0.2 7.6 46.4 21.3 0.0 15.4 0.7 25.0 6.4 34.8 21.7 38.1 13.7 43.9 27.7 41.1 8.9 3.8 27.2 27.2 35.4 31.0 15.6 8.2 0.1 20.0 0.1 20.6 0.0 0.0 0.0 2.8 0.0 1.4 0.5 6.9 6.9 0.2 0.3 1.5 3.2 0.3 0.9 0.3 0.1 8.7 2.0 16.8 19.8 17.3 22.0 19.1 19.3 25.1 25.2 24.0 22.0 19.4 24.2 42.0 25.6 28.2 11.8 6.0 44.7 143.4 35.3 27.3 14.9 52.8 68.7 231.2 17.2 55.2 20.2 33.3 0.7 12.0 12.8 72.4 26.9 4964.0 203.9 29.3 28.4 33.9 3.6 20.2 7.6 5.0 56.3 18.8 24.0 43.8 10.0 18.5 0.2 8.0 10.1 14.1 29.3 28.5 4.1 19.7 12837.2 69.9 11.5 23.2 3.7 1.0 28.5 3.1 9.0 12.7 10.2 14.3 50.4 3.4 37.4 1.3 36.6 329.7 71.1 19.7 131.0 40.5 854.2 192.2 10.4 34.2 1.6 25.3 55.9 14.7 83.1 MLH1 "COCA2, FCC2, HNPCC, HNPCC2" ENSG00000076242 "MutL homolog 1" P40692 3 36993350-37050846 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013294, HPA052707, HPA060714, CAB070868" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB013294: AB_2533406, CAB070868: , HPA052707: AB_2681923, HPA060714: AB_2684348" "unprognostic (1.26e-2)" "unprognostic (3.88e-3)" "unprognostic (2.36e-2)" "unprognostic (1.82e-1)" "unprognostic (3.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (8.24e-5)" "unprognostic (3.36e-2)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (8.63e-3)" "unprognostic (2.10e-3)" "unprognostic (4.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (8.86e-2)" 15.6 17.9 7.3 17.4 8.0 22.1 15.4 7.1 9.1 17.4 7.6 17.4 12.0 16.3 14.0 14.3 14.9 11.1 35.4 6.9 8.3 16.0 19.1 15.8 21.9 8.6 7.4 15.1 16.6 22.4 22.7 14.8 7.6 16.2 14.5 9.6 12.1 14.0 49.1 13.4 13.4 19.2 7.1 18.8 15.5 25.4 7.7 28.4 19.2 42.2 24.3 17.2 14.0 9.0 37.1 56.7 66.7 0.2 25.9 34.5 30.7 54.7 44.4 64.1 62.3 43.4 40.1 92.2 25.0 44.1 33.6 24.7 65.2 45.8 68.5 42.2 32.1 68.1 42.3 54.9 23.2 81.9 40.5 28.4 29.0 54.8 57.8 21.9 37.6 55.0 86.0 32.0 66.2 27.6 81.0 22.2 49.4 38.4 31.6 4.6 90.6 40.2 35.1 39.3 14.2 36.1 52.1 56.9 32.7 33.3 79.9 55.6 28.8 46.0 50.5 44.0 65.9 29.1 93.7 88.1 37.8 71.9 45.7 12.6 12.5 15.1 12.7 22.6 9.8 11.3 7.7 11.4 14.3 9.7 8.4 9.6 2.6 7.8 29.2 5.9 15.0 11.0 7.3 8.0 7.1 9.1 6.9 8.3 8.6 7.4 7.6 7.1 7.7 9.0 10.8 25.6 15.8 22.9 18.5 7.1 12.4 18.7 7.4 18.5 9.6 9.7 41.8 12.8 15.8 11.0 10.4 33.4 16.0 6.1 19.6 14.6 31.3 12.5 11.3 10.7 5.4 19.0 18.5 14.7 26.9 14.4 12.2 9.5 7.6 13.0 13.6 14.9 20.1 3.3 21.6 8.6 16.2 16.3 8.9 13.2 11.1 13.8 8.8 10.3 18.2 15.9 11.3 27.2 31.3 9.3 7.4 13.9 22.1 6.4 5.3 12.9 16.5 18.1 13.1 10.0 14.0 58.6 29.3 9.3 5.5 20.0 15.9 14.8 8.4 6.5 MLLT1 "ENL, LTG19, YEATS1" ENSG00000130382 "MLLT1 super elongation complex subunit" Q03111 19 6210381-6279975 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Cytotrophoblasts: 570.1;Syncytiotrophoblasts: 1138.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031166 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nucleoli fibrillar center" "HPA031166: AB_10601874" "unprognostic (3.21e-1)" "unprognostic (2.75e-3)" "unprognostic (4.84e-2)" "unprognostic (3.36e-2)" "unprognostic (2.47e-1)" "prognostic favorable (6.03e-5)" "unprognostic (1.30e-3)" "unprognostic (1.44e-2)" "unprognostic (1.56e-1)" "unprognostic (1.98e-1)" "unprognostic (3.93e-3)" "unprognostic (4.76e-2)" "unprognostic (3.65e-3)" "unprognostic (1.14e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (7.99e-3)" 28.9 22.4 33.3 16.5 31.5 8.7 26.4 32.2 38.0 42.9 26.7 41.4 12.2 40.5 13.2 25.6 42.6 9.9 35.5 36.4 26.2 30.0 37.5 33.5 10.9 25.8 28.3 47.7 26.8 20.9 28.9 42.6 21.8 40.8 5.6 13.5 24.0 15.6 34.8 30.8 24.3 13.3 19.8 27.0 30.0 16.8 29.9 11.9 36.8 12.7 7.5 37.3 28.8 27.0 49.5 23.8 28.7 34.1 22.0 19.0 33.3 29.9 19.3 24.7 25.1 39.5 16.2 35.6 38.1 39.4 27.6 30.2 22.9 29.4 14.6 30.2 35.9 44.3 66.0 30.1 42.2 29.0 39.0 30.7 25.2 23.6 19.1 27.1 28.2 31.5 43.6 40.4 16.4 27.1 49.8 27.8 35.0 24.6 49.5 42.3 21.4 28.7 13.4 30.1 49.7 45.2 30.9 33.8 37.8 14.1 30.6 34.1 29.8 34.3 26.5 53.7 41.8 49.1 41.0 28.0 39.6 49.3 49.9 0.1 0.8 0.2 0.7 1.2 0.9 0.5 0.4 0.7 0.6 0.5 0.4 0.5 2.0 0.8 1.5 2.0 0.2 0.7 33.3 31.5 32.2 38.0 36.4 26.2 25.8 28.3 21.8 19.8 29.9 27.0 20.5 22.4 32.7 12.1 5.2 0.1 13.2 0.0 2.8 29.8 13.6 13.5 23.4 5.7 8.6 12.9 18.8 570.1 11.1 5.8 7.9 12.6 27.5 34.8 21.7 21.7 4.9 1.3 10.8 16.6 38.6 14.8 13.3 14.5 10.1 16.2 23.6 18.9 60.9 58.9 13.3 9.9 0.0 15.6 0.0 57.8 19.0 12.1 0.0 11.2 13.2 35.6 10.3 8.0 16.7 13.0 3.6 18.4 8.6 17.8 8.4 6.9 4.4 15.8 26.3 20.7 11.0 10.6 5.7 7.2 0.1 1138.2 5.8 19.5 9.6 14.7 MLLT10 AF10 ENSG00000078403 "MLLT10 histone lysine methyltransferase DOT1L cofactor" P55197 10 21524646-21743630 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.0" "Cell type enhanced" "Detected in all" "Excitatory neurons: 201.3;Spermatocytes: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005736, HPA005747, HPA072790" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA005736: , HPA005747: AB_1079393, HPA072790: " "unprognostic (6.58e-2)" "unprognostic (1.57e-1)" "unprognostic (7.32e-2)" "unprognostic (1.47e-2)" "unprognostic (1.31e-2)" "prognostic favorable (8.75e-4)" "unprognostic (1.03e-3)" "unprognostic (9.56e-3)" "unprognostic (9.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.69e-2)" "unprognostic (7.85e-2)" "unprognostic (6.57e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" 15.6 13.0 11.9 12.0 13.6 30.5 14.4 21.5 16.0 18.2 16.6 20.8 9.1 18.7 16.0 16.1 17.4 11.4 17.1 11.5 15.2 15.1 15.6 14.6 15.3 14.6 11.9 24.7 13.5 18.6 12.6 16.4 14.1 13.0 12.7 20.6 13.7 11.8 15.6 25.4 13.2 16.8 11.9 12.8 12.3 93.0 13.7 23.2 21.8 14.2 14.5 19.1 16.5 18.6 32.1 29.6 38.3 22.2 23.3 25.0 44.1 19.6 10.6 21.7 21.6 29.5 31.3 34.9 10.8 20.7 21.1 24.1 43.3 25.1 22.2 25.0 21.9 59.2 24.5 44.5 29.6 1.6 33.4 21.3 28.6 17.7 19.2 21.8 30.1 34.3 65.4 26.5 19.3 28.1 44.1 28.5 17.3 17.5 9.2 36.6 23.5 31.7 23.2 12.6 13.8 39.6 24.7 29.0 45.8 30.7 13.3 37.1 29.8 14.7 24.6 26.7 18.9 23.5 32.2 43.4 15.4 21.5 9.9 10.3 6.5 13.5 5.0 4.1 4.6 5.3 6.1 6.1 5.1 4.3 6.6 6.0 4.8 4.6 4.7 7.5 5.5 2.5 11.9 13.6 21.5 16.0 11.5 15.2 14.6 11.9 14.1 11.9 13.7 18.6 33.3 28.9 40.4 155.7 25.1 37.7 17.4 22.4 44.3 38.4 19.9 20.7 31.5 18.6 19.6 18.4 43.8 34.0 24.9 13.3 13.7 14.6 66.1 16.1 26.6 28.7 3.5 30.9 201.3 12.8 58.6 26.6 21.9 21.3 25.2 28.6 26.0 22.7 28.9 30.3 169.6 16.3 26.4 36.1 23.0 109.0 39.4 28.6 48.0 107.7 29.7 17.8 21.6 148.3 160.0 13.2 14.6 48.2 23.5 22.7 18.8 23.1 18.7 53.7 39.5 31.4 35.7 233.8 57.4 48.5 43.9 50.2 29.5 24.2 18.0 13.5 MLLT11 AF1Q ENSG00000213190 "MLLT11 transcription factor 7 cofactor" Q13015 1 151060397-151069544 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 54.1;Early spermatids: 76.9;Excitatory neurons: 57.9;Late spermatids: 215.6" "Cancer enriched" "Detected in all" 4 "glioma: 29.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 216.7;EFO-21: 164.9;SH-SY5Y: 238.6;U-698: 207.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000540 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA000540: AB_2666024" "unprognostic (2.96e-2)" "unprognostic (1.98e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (1.69e-1)" "unprognostic (1.96e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.49e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.25e-12)" "unprognostic (5.66e-3)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (3.94e-3)" 5.3 19.0 59.4 4.7 61.8 2.0 2.5 41.1 109.3 4.5 8.8 7.2 1.6 10.7 1.3 4.0 6.2 6.0 38.1 66.2 80.6 3.8 2.0 3.8 2.1 63.1 50.5 8.2 3.1 16.2 10.4 1.0 66.1 4.3 3.6 35.6 3.8 1.5 11.3 2.6 4.9 13.8 29.9 4.6 5.1 2.8 49.7 20.6 3.8 10.8 2.1 4.0 3.9 57.1 6.3 31.0 216.7 34.4 3.5 5.8 1.4 11.6 15.2 13.2 24.0 3.0 12.6 10.0 164.9 10.6 35.9 4.5 54.3 13.0 7.6 65.8 14.5 28.9 17.7 0.9 6.9 0.8 1.0 9.9 1.6 73.5 2.9 42.2 100.1 43.3 30.8 2.3 43.6 1.4 106.4 19.0 95.7 0.6 4.4 99.8 28.1 0.6 25.5 1.7 132.8 238.6 0.8 1.3 6.9 142.5 5.3 2.7 65.9 27.0 29.0 9.2 24.7 2.4 3.2 207.1 70.0 0.6 51.7 1.1 0.3 1.4 5.9 0.6 2.7 2.5 3.9 6.2 0.7 1.9 5.3 9.1 1.6 4.0 0.9 1.4 4.1 3.2 59.4 61.8 41.1 109.3 66.2 80.6 63.1 50.5 66.1 29.9 49.7 57.1 1.4 0.0 1.1 11.8 4.2 3.6 5.0 14.6 4.6 54.1 2.5 4.8 10.2 1.5 2.2 3.7 8.4 2.9 15.3 0.1 17.6 3.9 76.9 0.8 11.3 5.2 10.7 6.3 57.9 1.2 2.5 17.5 2.0 0.9 4.5 4.3 4.2 0.4 6.0 37.0 40.6 0.1 16.2 6.6 14.5 215.6 2.1 12.3 5.4 10.3 33.3 20.6 19.6 16.1 14.4 3.0 0.2 3.8 4.8 1.3 0.2 2.4 0.6 26.3 0.0 3.4 30.0 8.6 12.3 2.8 3.4 7.4 9.9 3.0 0.2 4.3 MLLT3 "AF-9, AF9, YEATS3" ENSG00000171843 "MLLT3 super elongation complex subunit" P42568 9 20341669-20622499 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Astrocytes: 144.6;Excitatory neurons: 284.0;Inhibitory neurons: 288.4;Intestinal goblet cells: 112.3;Microglial cells: 114.3;Oligodendrocyte precursor cells: 254.3;Oligodendrocytes: 216.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "NK-cells: 5.1;T-cells: 16.3" "Cell line enriched" "Detected in many" 5 "HEL: 316.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001824 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA001824: AB_1079394" "unprognostic (3.31e-1)" "unprognostic (2.22e-1)" "unprognostic (1.23e-3)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "unprognostic (7.57e-2)" "unprognostic (3.83e-2)" "unprognostic (1.01e-3)" "unprognostic (2.12e-1)" "unprognostic (3.92e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-2)" "prognostic favorable (1.84e-4)" "unprognostic (1.85e-1)" "unprognostic (4.81e-2)" "unprognostic (1.40e-2)" "unprognostic (1.68e-1)" 6.7 15.4 11.6 10.0 16.0 37.3 12.7 9.7 16.4 11.7 2.6 28.8 8.1 12.6 10.6 8.8 12.8 13.9 8.9 17.4 10.9 12.3 2.4 12.6 11.3 6.4 7.8 11.9 4.8 10.1 9.8 11.9 6.6 12.7 37.8 8.2 25.3 12.8 11.1 7.0 15.7 12.3 6.4 6.9 20.1 4.2 9.1 24.3 27.2 11.1 8.3 10.6 6.3 12.0 8.7 24.4 8.4 9.6 19.8 11.7 5.4 22.3 37.8 9.6 11.5 22.8 8.2 36.1 11.9 10.6 3.2 4.4 8.5 38.0 9.2 68.0 23.6 316.4 68.3 12.3 13.8 4.9 20.1 9.4 15.4 3.8 25.3 34.7 9.8 13.8 0.4 42.5 21.7 6.8 24.9 18.6 5.1 50.8 6.8 0.0 15.4 8.8 50.0 13.4 27.2 11.0 18.1 10.2 10.1 8.4 9.3 11.9 6.5 0.0 5.6 6.0 8.3 18.4 18.7 13.1 0.4 10.6 4.8 2.3 0.4 0.6 4.5 0.3 4.3 0.6 8.6 6.5 0.9 1.4 16.3 10.3 0.1 5.1 0.4 0.6 10.8 3.6 11.6 16.0 9.7 16.4 17.4 10.9 6.4 7.8 6.6 6.4 9.1 12.0 20.0 28.9 30.0 144.6 8.0 8.3 15.9 18.7 21.1 7.8 21.2 12.3 13.5 18.6 32.5 22.0 33.3 0.9 17.3 23.5 13.7 29.2 3.0 10.3 17.5 13.7 33.0 28.4 284.0 8.2 6.1 18.0 23.0 19.5 12.0 8.7 11.4 2.2 2.4 5.0 288.4 112.3 16.2 1.9 6.5 7.4 13.7 7.1 23.2 114.3 2.7 31.9 17.5 254.3 216.6 27.3 23.6 9.4 18.2 14.5 13.8 9.0 11.7 2.2 0.0 25.2 21.6 1.0 10.5 14.2 8.4 1.6 33.3 9.8 27.0 15.7 MLLT6 "AF17, FLJ23480" ENSG00000275023 "MLLT6, PHD finger containing" P55198 17 38705273-38729795 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 291.2;Cone photoreceptor cells: 204.3;NK-cells: 218.3;Rod photoreceptor cells: 200.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 14.9;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004021 Approved Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA004021: AB_1853995" "prognostic favorable (4.18e-4)" "unprognostic (1.50e-1)" "unprognostic (2.53e-1)" "unprognostic (1.44e-2)" "unprognostic (1.29e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.98e-2)" "unprognostic (1.79e-2)" "unprognostic (1.77e-1)" "unprognostic (7.12e-3)" "prognostic favorable (7.41e-4)" "unprognostic (1.78e-1)" "unprognostic (1.84e-2)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (2.05e-1)" "unprognostic (2.46e-3)" 38.0 45.5 1.7 2.8 1.1 2.0 42.5 2.4 2.0 55.0 0.2 49.8 3.0 46.0 1.3 35.2 63.7 0.9 48.8 0.9 0.0 56.5 20.7 45.3 2.2 0.7 0.0 81.1 52.8 0.9 79.2 1.2 0.1 52.1 0.8 3.7 44.4 1.5 81.8 36.6 54.4 1.1 0.0 67.0 48.5 33.4 0.6 0.8 70.5 1.0 0.8 44.7 40.7 0.0 2.1 3.8 0.8 1.2 0.8 0.8 0.9 3.3 0.3 0.3 0.6 2.3 1.5 5.4 3.7 0.5 1.1 4.2 0.1 1.2 0.6 14.9 6.5 3.2 7.4 3.5 0.0 2.5 2.6 0.7 0.1 1.1 0.5 2.4 0.9 1.5 2.4 4.4 0.5 1.0 3.7 0.8 0.9 0.3 1.3 2.5 2.8 1.5 0.2 4.6 3.8 4.0 2.1 1.2 1.5 0.8 2.2 0.1 3.9 1.3 2.3 3.2 3.4 10.0 5.8 4.6 1.4 1.8 1.0 0.4 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.7 1.1 2.4 2.0 0.9 0.0 0.7 0.0 0.1 0.0 0.6 0.0 60.8 48.1 46.8 46.4 35.3 30.5 25.2 20.2 18.2 291.2 41.2 35.6 32.2 24.3 31.5 33.1 204.3 20.1 69.5 24.4 11.7 25.5 3.2 25.0 35.0 46.0 49.7 9.9 24.5 42.4 4.5 27.9 22.4 35.5 37.3 49.1 31.8 12.6 13.6 119.5 18.8 31.5 10.2 18.0 39.9 6.0 46.9 22.7 19.6 45.0 28.4 36.2 218.3 32.6 26.5 32.2 25.6 42.2 28.0 40.0 37.1 15.7 25.8 200.9 32.9 51.3 37.0 17.1 23.4 27.1 29.1 38.3 65.0 27.9 39.3 29.4 MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 333.5;kidney: 302.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 273.3;Proximal enterocytes: 372.4;Proximal tubular cells: 125.7;Syncytiotrophoblasts: 126.0" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Group enriched" "Detected in many" 5 "basal ganglia: 17.3;medulla oblongata: 9.3;pons: 10.9;thalamus: 4.6" "Immune cell enriched" "Detected in some" 122 "neutrophil: 139.4" "Lineage enriched" "Detected in many" 122 "granulocytes: 139.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 684.4;BJ hTERT+: 1116.9;HSkMC: 651.1" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Group enriched" "Detected in many" 4 "basal ganglia: 32.3;olfactory bulb: 8.5;spinal cord: 15.9" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" 103.9 1.0 0.7 4.5 17.3 11.5 38.5 1.5 1.9 22.7 0.3 1.9 333.5 13.3 22.5 2.3 1.9 13.4 4.3 0.1 0.6 302.5 56.1 27.6 10.3 9.3 2.3 0.9 1.2 0.5 0.6 73.0 10.9 79.6 3.4 0.1 6.1 44.5 20.3 1.9 289.7 1.5 0.9 7.9 1.6 1.3 4.6 16.6 1.2 23.5 12.3 6.0 7.6 0.4 0.1 0.0 0.9 0.3 280.1 684.4 1.6 160.3 1116.9 82.2 209.8 0.0 0.3 172.9 0.1 130.1 107.4 0.5 5.2 6.1 201.3 0.0 0.8 0.0 0.1 0.2 229.6 0.0 0.0 651.1 1.0 40.4 308.1 89.4 59.5 0.4 0.2 0.3 135.1 0.7 0.4 1.0 6.1 0.5 1.1 303.3 139.9 1.6 5.2 1.9 0.5 1.5 0.1 0.5 31.9 68.3 0.2 0.2 165.8 356.4 0.8 115.7 27.9 0.1 0.0 217.3 42.5 0.1 7.3 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 139.4 0.0 0.0 1.1 0.0 0.0 0.7 17.3 1.5 1.9 0.1 0.6 9.3 2.3 10.9 0.9 4.6 0.4 5.9 9.6 13.0 0.3 2.3 0.8 74.1 2.5 0.0 0.0 1.5 64.1 1.6 21.5 11.2 22.0 0.0 82.1 6.9 0.0 9.8 0.2 0.5 6.2 273.3 6.6 0.0 0.0 2.2 0.0 57.8 40.6 0.0 5.7 2.5 0.0 2.9 53.2 8.9 0.0 8.1 9.9 2.0 3.1 1.2 0.5 4.1 10.7 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.6 13.8 1.2 0.1 40.0 372.4 125.7 1.6 0.0 0.0 17.4 11.1 0.2 0.5 0.1 0.3 126.0 2.5 0.1 12.6 33.6 MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 75.7;stomach 1: 47.6;urinary bladder: 52.2" "Cell type enriched" "Detected in many" 10 "Pancreatic endocrine cells: 2239.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1139.1;HBF TERT88: 1094.4;HUVEC TERT2: 2954.4;WM-115: 1454.1" "Not detected" "Not detected" HPA004920 Approved Vesicles "Secreted to extracellular matrix" NA NA 7730000 55000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" 0.3 0.1 0.0 26.7 0.0 0.3 0.2 0.0 1.3 0.1 0.0 6.1 7.9 10.7 0.0 4.2 0.1 75.7 0.4 0.0 0.1 1.0 0.8 6.7 0.1 0.0 0.0 0.0 1.8 0.0 0.1 7.2 0.0 0.4 6.8 0.0 6.9 0.2 0.0 0.6 13.0 1.2 0.0 2.1 47.6 0.1 0.1 0.3 0.2 0.0 1.7 52.2 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.1 0.0 517.1 1139.1 456.6 118.2 9.1 1.0 0.0 5.2 275.5 175.2 4.6 0.0 160.0 1094.4 0.0 1.0 0.0 0.0 0.0 2.9 0.0 0.5 0.3 0.8 470.1 39.6 0.1 2954.4 0.0 1.5 0.5 0.3 0.0 0.0 0.0 0.4 189.3 20.8 0.0 0.1 0.0 0.7 2.2 0.0 0.1 4.8 0.0 1.6 0.1 0.5 0.0 155.0 374.1 0.6 16.8 1.3 0.1 0.0 0.0 8.8 0.0 1454.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.3 3.2 2.6 0.0 0.2 2.3 22.4 90.4 0.0 0.0 0.0 0.0 0.1 30.0 15.8 3.7 0.0 0.0 0.0 0.2 0.0 143.7 0.0 0.1 0.2 113.2 0.0 0.0 0.1 204.8 0.1 11.5 25.5 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 1.9 0.4 0.0 0.0 15.5 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2239.5 1.2 0.0 0.0 30.9 0.7 0.2 1.3 0.0 0.0 1.8 10.5 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 44.3 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "endometrium 1: 265.4" "Cell type enriched" "Detected in some" 38 "Basal respiratory cells: 3913.2" "Group enriched" "Detected in many" 4 "cervical cancer: 47.8;head and neck cancer: 102.2;lung cancer: 42.3" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 11.8;HUVEC TERT2: 15.1;SCLC-21H: 4.7" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 765000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favorable (7.12e-4)" 0.1 0.0 0.1 7.7 0.0 0.1 0.1 0.0 0.8 1.2 0.0 0.4 1.1 265.4 0.0 0.2 0.0 1.3 0.0 0.2 0.3 0.1 1.0 2.0 0.1 0.1 0.3 0.2 0.2 0.0 0.0 1.3 0.3 1.4 0.2 0.0 1.6 0.0 0.0 0.1 0.8 0.2 0.0 0.0 2.9 0.5 1.9 0.6 0.0 0.2 0.7 4.4 3.2 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 11.8 0.6 0.1 0.1 0.3 0.0 0.0 3.3 1.8 0.2 2.7 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.5 0.0 15.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 2.8 0.5 1.6 0.0 0.0 0.0 0.0 0.6 4.7 0.0 2.4 0.0 0.0 0.8 0.0 0.0 1.9 3.5 1.2 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.3 0.1 0.3 0.3 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 51.3 3913.2 0.0 0.0 0.7 0.0 0.1 0.0 85.4 29.5 0.0 0.0 0.0 0.4 0.0 34.0 6.1 6.4 2.5 9.0 0.0 0.0 0.0 14.6 0.0 6.3 0.0 12.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 9.5 1.3 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 102.5 0.1 0.0 0.0 42.5 0.0 0.1 29.3 0.0 0.0 0.0 11.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.2 MMP11 STMY3 ENSG00000099953 "Matrix metallopeptidase 11" P24347 22 23768226-23784316 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 64.8;endometrium 1: 142.8;placenta: 39.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 84.9;Extravillous trophoblasts: 37.6;Granulosa cells: 61.9;Smooth muscle cells: 35.8" "Cancer enhanced" "Detected in all" "pancreatic cancer: 119.1" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 4.4" "Cell line enhanced" "Detected in many" "AN3-CA: 38.4;hTERT-RPE1: 19.7;REH: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002593, HPA055204, HPA068864" Approved Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 640000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Cytosol "CAB002593: , HPA055204: , HPA068864: AB_2686051" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.84e-3)" "unprognostic (2.77e-2)" "unprognostic (6.73e-2)" "unprognostic (2.14e-2)" "unprognostic (5.15e-1)" "unprognostic (2.73e-2)" "unprognostic (2.20e-1)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.05e-2)" "unprognostic (6.78e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-2)" 3.3 1.6 0.4 1.4 0.3 0.5 2.2 0.3 1.2 64.8 0.3 3.9 6.8 142.8 0.1 1.0 5.7 6.8 7.2 0.3 0.4 2.5 0.6 1.4 3.9 0.4 0.4 12.5 1.3 3.3 0.5 39.6 0.4 1.9 3.5 0.0 5.3 1.5 0.9 3.8 6.0 9.4 0.4 1.4 2.6 6.7 0.4 3.1 1.3 0.9 1.7 2.9 3.6 0.4 0.3 0.0 4.8 38.4 5.7 8.3 0.1 0.6 10.4 1.3 0.8 0.4 1.3 1.3 5.1 2.8 1.8 0.2 2.2 0.0 0.4 0.0 0.8 0.0 0.0 2.2 4.2 0.0 0.0 5.4 0.9 1.1 0.1 19.7 6.0 0.4 0.6 0.0 1.4 0.3 0.1 0.1 1.4 1.2 0.2 16.6 0.0 0.4 0.7 0.0 6.0 10.3 3.9 0.6 0.0 5.9 3.6 0.0 2.7 0.6 0.0 1.6 0.1 0.1 0.2 5.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.4 0.3 0.3 1.2 0.3 0.4 0.4 0.4 0.4 0.4 0.4 0.4 1.2 0.0 2.5 0.3 3.4 1.0 0.8 0.8 0.6 0.4 1.9 0.5 6.1 1.5 0.1 0.0 0.0 0.7 1.8 0.4 1.9 8.6 10.3 4.4 84.9 0.9 1.8 0.0 0.2 0.7 37.6 8.4 1.5 4.1 1.3 61.9 1.1 0.0 0.8 0.0 0.4 1.3 2.0 0.0 1.1 10.5 0.6 1.0 1.8 1.0 0.0 0.3 0.0 0.0 0.2 1.4 0.2 0.4 0.2 0.5 0.1 2.2 0.8 0.5 0.0 2.7 35.8 3.1 5.5 0.5 0.6 18.6 2.0 5.7 1.0 0.3 MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102874982 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.7;lymphoid tissue: 40.4;urinary bladder: 16.0" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 303.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BJ: 3.3;fHDF/TERT166: 11.4;hTEC/SVTERT24-B: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" NA NA "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" 0.5 0.0 0.0 40.4 0.1 0.0 0.4 0.0 0.0 0.1 0.0 13.5 6.8 0.6 0.0 0.4 0.0 2.6 0.0 0.0 0.3 0.9 0.1 0.6 7.0 0.1 0.1 0.0 0.1 0.0 0.0 7.4 0.1 1.3 15.7 0.0 2.4 0.0 0.0 0.5 7.8 2.2 0.1 3.7 3.5 0.0 0.1 3.9 0.0 0.0 19.4 16.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 11.4 0.1 0.4 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 18.6 303.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.0 2.2 MMP13 CLG3 ENSG00000137745 "Matrix metallopeptidase 13" P45452 11 102942995-102955732 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "urinary bladder: 12.9" "Cell type enriched" "Detected in some" 12 "Basal respiratory cells: 426.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 70.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 17.9;PC-3: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" CAB002742 Supported "Secreted to extracellular matrix" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB002742: " "unprognostic (8.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.75e-2)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" "unprognostic (1.59e-3)" "unprognostic (1.32e-1)" "unprognostic (6.35e-3)" "unprognostic (1.69e-1)" "unprognostic (7.55e-3)" "unprognostic (2.24e-1)" "unprognostic (1.73e-8)" "unprognostic (2.12e-2)" "unprognostic (3.14e-1)" "unprognostic (4.14e-2)" "unprognostic (4.33e-2)" 0.1 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 12.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 17.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.0 6.7 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 2.4 1.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 426.0 0.0 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.8 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.0;Pancreatic endocrine cells: 144.7;Syncytiotrophoblasts: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 923.8;HHSteC: 794.2;HSkMC: 887.0;hTERT-RPE1: 925.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 151.5 31.7 5.6 59.9 5.0 1.6 101.5 5.7 7.5 181.3 61.8 77.2 39.5 167.3 19.0 92.1 82.1 148.2 41.3 6.6 7.2 35.9 13.2 91.8 24.8 11.9 8.4 90.2 36.0 65.3 14.2 118.9 9.2 59.9 36.6 9.6 78.1 45.5 18.8 127.5 69.4 106.0 7.3 30.8 57.7 11.7 13.2 13.0 50.0 16.1 30.8 103.9 111.1 10.6 90.6 1.2 26.3 2.0 923.8 651.6 455.9 270.1 606.4 93.3 158.5 21.3 337.4 0.9 146.4 301.9 24.6 216.3 0.3 262.2 99.7 1.1 0.6 37.2 1.7 5.0 794.2 0.4 1.3 887.0 148.7 334.7 288.3 925.5 492.9 0.6 0.8 2.1 185.1 0.7 0.4 79.4 14.7 17.7 52.4 2.1 96.0 0.2 61.4 148.1 0.3 0.6 187.3 0.3 574.2 104.4 1.0 79.5 436.8 724.9 53.7 198.2 329.6 0.8 1.6 1.1 410.9 0.6 396.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 5.0 5.7 7.5 6.6 7.2 11.9 8.4 9.2 7.3 13.2 10.6 13.9 12.8 3.0 2.0 3.4 34.0 23.4 105.4 39.3 0.0 14.1 17.5 4.7 50.1 42.2 7.3 0.0 105.6 0.3 19.9 11.7 63.0 0.4 16.1 81.6 35.2 7.8 0.0 0.0 28.7 244.0 84.0 25.5 14.8 3.8 9.3 32.9 2.7 89.5 0.0 0.0 24.5 34.6 20.2 32.7 2.4 72.1 38.0 37.4 4.7 21.5 14.3 0.0 0.5 0.1 144.7 33.0 54.9 0.3 21.8 19.9 11.7 46.8 0.8 39.5 11.1 73.9 0.8 0.8 33.7 34.2 122.7 2.5 15.6 18.6 37.9 MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.8;Distal enterocytes: 109.3;Proximal enterocytes: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 93.6;Hep G2: 51.1;OE19: 44.6;SK-BR-3: 47.3;WM-115: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" 11.9 3.8 8.9 4.4 6.0 0.4 7.6 7.3 11.2 5.7 5.8 28.0 40.2 3.5 1.1 4.6 6.1 14.3 41.2 6.9 8.7 14.9 50.1 9.9 2.1 15.8 10.6 1.1 18.5 12.7 8.8 28.4 16.8 4.4 14.3 1.5 8.4 9.5 7.0 4.3 33.0 3.7 5.8 9.3 29.6 34.9 18.7 1.0 46.7 5.6 1.3 5.1 2.8 8.6 15.3 11.4 5.8 30.4 6.0 0.3 93.6 1.4 0.8 5.4 1.2 9.1 38.3 0.2 17.7 1.6 4.2 21.0 5.1 4.4 1.6 0.1 10.0 0.1 4.9 51.1 7.7 0.3 19.5 3.1 7.8 0.9 2.3 8.4 3.7 8.5 12.9 0.1 1.8 7.6 0.7 2.6 17.2 44.6 3.2 7.6 0.7 8.3 16.6 5.4 1.6 10.4 20.0 47.3 9.5 13.2 5.2 8.2 3.4 0.4 9.1 3.5 1.3 0.2 0.1 0.3 1.9 2.3 78.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.9 6.0 7.3 11.2 6.9 8.7 15.8 10.6 16.8 5.8 18.7 8.6 14.3 19.2 14.4 9.1 0.7 2.5 1.0 4.9 2.8 3.4 5.0 3.0 24.7 55.8 12.6 18.4 16.7 48.2 1.6 109.3 1.9 35.7 5.0 3.6 1.1 17.2 11.4 2.7 1.4 12.0 49.2 4.5 35.2 6.4 0.0 18.6 13.6 39.2 12.9 1.7 1.2 33.3 10.2 3.0 0.3 6.9 0.9 0.9 1.8 1.0 0.0 2.1 0.0 4.5 1.4 13.3 38.5 3.4 0.3 1.3 67.3 7.3 6.0 1.9 0.0 0.7 2.4 0.9 4.6 3.3 2.3 48.4 0.7 23.2 45.0 1.7 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;salivary gland: 286.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.4;Basal respiratory cells: 25.8;Early spermatids: 24.2;Extravillous trophoblasts: 13.4;Fibroblasts: 17.9;Prostatic glandular cells: 11.9;Smooth muscle cells: 10.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 4 "thalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BJ: 1545.7;BJ hTERT+: 4229.3;fHDF/TERT166: 1846.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 460000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 90.7 0.1 0.3 20.1 0.4 0.0 36.6 0.2 1.6 0.3 0.1 6.1 2.4 38.1 0.2 0.8 0.2 1.9 0.2 0.4 1.6 0.4 1.6 0.3 0.0 0.4 0.4 0.1 0.3 0.1 0.9 0.4 0.3 2.2 2.3 0.0 286.1 2.2 39.6 63.7 4.5 1.6 0.3 0.0 10.5 0.1 7.3 0.1 2.6 0.4 1.3 13.9 0.5 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1545.7 4229.3 27.0 8.7 0.1 0.2 0.0 0.0 1846.6 96.9 0.0 0.1 0.1 45.1 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 4.6 0.2 122.0 5.3 0.0 0.0 0.0 0.2 0.3 4.7 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.9 0.0 0.3 0.0 140.5 13.1 1.6 0.5 0.0 0.0 0.2 56.8 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.6 0.4 1.6 0.4 0.4 0.3 0.3 7.3 0.3 0.0 3.2 0.0 0.0 0.0 8.4 20.4 25.8 0.0 0.0 0.1 0.1 0.3 4.3 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.8 24.2 0.0 0.3 0.5 0.0 0.0 0.2 1.4 13.4 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.1 0.0 2.2 1.2 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 4.0 0.0 0.0 11.9 1.0 0.9 0.1 0.0 0.0 1.8 10.2 0.0 1.8 0.0 3.4 0.3 0.6 0.0 0.8 7.4 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 509.9;salivary gland: 267.9;urinary bladder: 211.2" "Cell type enriched" "Detected in many" 8 "Ductal cells: 8176.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 145.9;CAPAN-2: 815.9;EFO-21: 189.8;RPTEC TERT1: 350.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 35000 "Cluster 5: Breast - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 3.8 0.1 0.0 2.0 0.0 0.3 168.7 0.0 0.3 13.3 0.0 1.6 0.6 97.4 27.9 21.3 91.2 509.9 0.2 0.0 0.0 140.2 3.4 31.6 1.9 0.0 0.0 0.7 85.2 0.0 0.3 0.8 0.0 54.0 1.0 0.0 267.9 34.9 0.1 32.4 0.6 4.8 0.0 0.2 7.3 0.6 0.4 3.3 0.4 0.0 29.3 211.2 1.7 0.0 0.2 145.9 0.0 0.4 0.0 0.0 0.2 0.0 2.1 0.1 0.1 1.9 815.9 0.0 189.8 0.0 0.0 1.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.6 1.0 0.1 0.2 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.5 11.8 0.0 0.0 0.0 0.0 350.1 1.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.1 0.0 0.7 3.0 0.0 1.6 0.1 0.6 0.4 1.0 5.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 86.6 43.3 0.0 1.5 1.0 382.2 135.4 1.2 0.0 124.2 93.7 0.7 100.1 401.2 1017.0 0.0 0.7 2.9 1.2 0.0 8176.2 6.1 62.1 3.3 8.8 0.0 0.0 0.0 209.4 0.3 3.4 0.0 124.6 2.5 0.0 0.0 0.0 98.0 0.0 0.0 0.0 38.7 0.6 0.3 10.3 11.8 12.6 0.0 0.0 65.2 0.0 0.0 0.0 0.0 850.9 0.0 0.0 0.1 603.3 0.0 33.9 72.6 0.0 0.0 0.0 31.4 0.1 0.2 17.0 2.4 0.8 3.6 0.0 2.3 840.8 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 501.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 4.0;Macrophages: 1.5" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cell line enriched" "Detected in some" 8 "WM-115: 70.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 360000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 0.5 0.0 0.0 0.3 0.1 501.1 0.2 0.1 0.2 0.0 0.2 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.6 4.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.2 0.0 13.8 0.1 0.0 0.6 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 376.0;lymphoid tissue: 105.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 260.1;Langerhans cells: 606.0;Macrophages: 230.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.1;thalamus: 4.8" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.2" "Lineage enriched" "Detected in single" 341 "granulocytes: 272.2" "Cell line enriched" "Detected in some" 13 "NB-4: 360.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" NA NA 43300000 61000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" 19.5 0.6 0.5 61.9 0.8 376.0 8.2 0.4 3.1 2.9 0.8 5.7 11.6 1.0 0.0 2.2 2.2 3.0 3.2 0.3 0.9 2.6 3.8 21.1 103.2 0.8 0.5 0.8 1.6 0.1 1.1 2.0 0.7 1.9 3.4 0.6 3.6 0.4 0.7 3.2 12.4 1.9 0.4 105.3 11.3 1.3 4.8 17.0 2.1 0.9 36.5 12.0 1.1 0.2 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.3 0.3 28.8 0.0 0.3 0.4 0.0 1.4 0.0 0.3 0.5 0.1 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 4.0 0.0 360.6 0.8 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.6 0.6 0.0 0.6 0.0 3.7 0.3 1.2 0.3 10.3 10.9 0.1 0.3 0.3 0.2 0.2 0.1 0.8 0.2 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 272.2 0.0 0.3 0.0 0.0 0.5 0.5 0.8 0.4 3.1 0.3 0.9 0.8 0.5 0.7 0.4 4.8 0.2 0.7 0.0 5.5 0.0 3.9 34.3 0.1 61.5 0.0 3.8 0.5 2.0 0.4 1.5 0.9 0.0 8.4 1.5 2.0 0.0 0.0 0.8 0.9 0.0 0.1 7.2 0.0 0.0 0.1 1.8 2.4 2.5 0.0 0.1 1.3 0.2 0.0 0.0 260.1 3.3 0.2 0.5 0.0 1.3 606.0 0.3 0.0 230.6 56.9 0.0 2.3 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.1 0.0 0.3 6.9 5.3 0.0 0.2 45.5 6.7 11.2 0.2 28.1 1.9 3.4 0.3 0.0 0.1 MN1 "MGCR, MGCR1, MGCR1-PEN" ENSG00000169184 "MN1 proto-oncogene, transcriptional regulator" Q10571 22 27748277-27801756 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.7;skeletal muscle: 61.6;tongue: 42.6" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Early spermatids: 22.3;Fibroblasts: 13.9;Langerhans cells: 11.2;Late spermatids: 15.2;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 30.7;HeLa: 12.7;hTERT-RPE1: 13.7;RH-30: 12.4;TIME: 20.1;U-2 OS: 16.3;U-2197: 17.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003072 Approved Approved Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003072: AB_1079399" "unprognostic (5.64e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-2)" "unprognostic (2.52e-2)" "unprognostic (7.01e-2)" "unprognostic (3.03e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (4.00e-2)" "unprognostic (7.33e-2)" "unprognostic (5.13e-7)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.28e-3)" "unprognostic (2.21e-4)" 4.1 0.8 6.0 1.6 20.7 1.3 2.3 6.4 9.5 2.2 0.5 6.1 0.8 2.7 1.0 3.6 4.3 3.0 6.7 1.9 5.3 0.9 0.4 3.3 0.1 4.3 13.0 9.6 0.7 0.1 2.7 1.3 6.8 2.3 0.9 1.8 2.7 1.2 61.6 1.8 2.1 2.5 2.1 0.4 4.0 0.8 8.5 0.3 2.1 42.6 0.7 3.3 3.5 3.1 0.0 1.5 30.7 0.9 0.6 1.3 0.0 0.7 1.1 0.0 0.0 0.0 0.1 0.0 3.1 5.7 1.3 2.7 1.5 1.8 0.0 0.0 0.8 0.0 12.7 0.0 0.7 0.0 0.3 0.1 3.5 0.7 3.0 13.7 0.3 0.0 0.0 0.2 1.0 0.0 0.0 0.4 4.0 0.0 2.8 5.3 12.4 0.0 0.4 0.0 0.1 0.4 2.7 0.0 0.0 7.5 0.3 0.1 20.1 1.0 16.3 17.9 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.0 20.7 6.4 9.5 1.9 5.3 4.3 13.0 6.8 2.1 8.5 3.1 2.1 3.2 2.3 12.1 0.3 4.2 0.1 2.6 3.4 8.4 1.8 0.6 7.4 1.5 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.4 22.3 1.4 1.0 6.6 0.0 0.0 6.4 1.0 0.1 13.9 0.5 3.1 0.0 0.6 2.5 0.6 0.3 0.0 9.6 0.0 2.0 1.4 11.2 15.2 5.0 2.7 0.0 2.8 0.3 3.9 0.0 13.0 4.3 2.8 0.0 10.1 1.3 0.2 0.0 0.1 0.1 0.7 0.0 2.4 2.3 0.4 1.1 1.9 2.7 0.0 0.3 0.4 0.0 0.2 MORC4 "FLJ11565, ZCW4, ZCWCC2" ENSG00000133131 "MORC family CW-type zinc finger 4" Q8TE76 X 106813871-107000212 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 79.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 131.4;Alveolar cells type 2: 130.4;Cytotrophoblasts: 329.8;Syncytiotrophoblasts: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000395, HPA015547, HPA050250" Enhanced Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA000395: AB_1079405, HPA015547: AB_2669216, HPA050250: AB_2681063" "prognostic unfavorable (3.56e-5)" "unprognostic (3.30e-3)" "unprognostic (1.09e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (6.29e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (5.56e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.60e-2)" "unprognostic (6.57e-2)" "unprognostic (4.89e-2)" "unprognostic (8.69e-2)" 13.4 30.9 24.8 7.8 35.5 11.8 12.2 47.8 51.0 12.1 17.8 8.5 10.4 11.5 16.3 9.6 10.4 10.1 7.0 32.4 22.4 10.8 21.1 8.8 5.6 11.1 11.4 17.4 15.1 11.7 6.2 79.9 16.6 12.4 10.8 22.3 10.9 11.5 20.2 18.7 10.0 11.4 3.9 6.0 8.4 20.2 16.6 5.6 10.2 10.3 7.0 7.5 11.1 55.7 29.8 121.0 11.4 26.4 35.0 40.3 60.5 28.7 30.8 14.6 18.3 64.6 13.1 3.7 14.2 30.5 23.9 22.5 39.8 25.5 17.1 4.6 23.0 6.4 40.7 27.1 25.6 4.7 13.9 20.8 24.3 19.6 28.6 85.7 13.1 4.1 3.9 41.4 32.7 26.7 10.7 6.4 8.9 82.0 45.2 4.2 22.9 4.3 47.0 23.3 9.2 11.5 35.4 33.9 23.0 15.9 19.7 5.0 12.6 22.5 21.4 44.7 15.7 11.1 16.2 11.5 24.0 3.8 16.2 8.3 1.5 1.8 1.9 1.3 1.7 1.7 1.9 1.5 0.7 2.7 2.1 1.7 3.7 1.5 1.7 2.5 1.5 0.4 24.8 35.5 47.8 51.0 32.4 22.4 11.1 11.4 16.6 3.9 16.6 55.7 8.6 131.4 130.4 6.2 5.1 17.5 19.1 4.9 21.1 5.4 11.5 9.5 3.0 10.0 61.8 5.5 4.2 329.8 10.4 3.6 21.5 9.9 0.9 6.2 11.5 13.6 1.8 0.4 4.2 7.4 28.2 33.4 10.2 15.5 66.3 10.3 7.5 24.0 23.4 1.7 6.5 10.5 6.1 2.1 5.0 1.8 11.1 8.2 12.4 3.7 0.3 6.7 3.1 15.1 8.7 7.5 6.7 11.7 5.8 16.4 4.4 12.7 62.2 7.2 26.3 16.9 12.0 9.9 26.6 19.7 16.1 257.8 11.9 10.1 10.1 11.8 MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 57 "HEL: 77.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nuclear membrane" "HPA007619: AB_1854080" "unprognostic (2.74e-1)" "unprognostic (6.56e-2)" "unprognostic (2.95e-1)" "unprognostic (8.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (5.94e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-4)" "unprognostic (2.39e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-4)" "unprognostic (1.42e-1)" 0.6 0.4 0.8 0.2 1.7 1.8 0.4 0.8 1.3 0.3 0.1 0.3 0.3 0.7 1.2 0.5 0.8 0.3 1.0 0.6 1.2 0.4 0.4 0.6 0.2 1.2 1.0 2.9 0.8 0.4 0.0 0.3 1.1 0.9 0.4 1.5 0.4 0.7 0.6 0.5 0.2 0.7 0.7 0.4 0.5 1.2 1.1 0.1 0.9 0.3 0.1 0.2 0.0 2.8 0.4 0.7 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.1 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.4 0.1 77.4 1.2 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.7 0.6 0.4 0.2 0.6 0.1 0.2 0.2 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.2 1.4 0.1 0.1 0.3 0.1 1.8 0.8 1.7 0.8 1.3 0.6 1.2 1.2 1.0 1.1 0.7 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "bone marrow: 4023.1" "Cell type enriched" "Detected in some" 30 "Erythroid cells: 87.4" "Cancer enhanced" "Detected in single" "stomach cancer: 1.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 6.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 94 "HL-60: 3517.4;NB-4: 4589.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" No NA 576000000 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles Nucleoplasm "CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (4.62e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.78e-1)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (6.92e-2)" "unprognostic (8.34e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-3)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" 0.5 0.4 0.8 0.6 0.6 4023.1 0.3 0.6 1.1 0.0 0.3 0.2 0.0 0.2 1.1 0.1 0.1 0.3 1.1 0.8 0.7 0.2 1.8 8.4 1.7 0.9 1.0 0.1 0.1 0.0 1.5 1.4 0.9 0.2 0.2 0.4 66.3 0.1 1.1 4.3 0.2 0.3 0.8 21.7 0.1 0.4 0.8 10.9 0.3 0.3 0.2 0.5 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 3517.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4589.9 0.0 0.0 0.0 5.3 3.2 0.6 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 4.0 0.0 0.0 6.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.1 7.5 0.8 0.6 0.6 1.1 0.8 0.7 0.9 1.0 0.9 0.8 0.8 0.7 0.0 0.0 0.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.9 0.0 0.5 0.1 0.0 0.1 0.0 87.4 0.3 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.7 0.3 0.9 0.0 0.2 0.0 0.0 1.2 0.0 1.3 0.0 2.9 0.0 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.1 0.3 0.1 0.0 0.1 0.6 0.0 0.0 0.0 MRE11 "ATLD, MRE11A" ENSG00000020922 "MRE11 homolog, double strand break repair nuclease" P49959 11 94415570-94493885 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Meiosis" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Cancer-related genes, Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Cytotrophoblasts: 39.2;Granulosa cells: 34.1;Syncytiotrophoblasts: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002691, CAB004081" Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB004081: AB_2145100, HPA002691: AB_1079409" "unprognostic (5.59e-3)" "unprognostic (4.35e-2)" "unprognostic (8.55e-2)" "unprognostic (2.76e-2)" "unprognostic (9.82e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (7.14e-4)" "unprognostic (2.85e-1)" "unprognostic (1.03e-2)" "unprognostic (1.34e-1)" "unprognostic (8.66e-3)" "unprognostic (6.96e-3)" "unprognostic (1.57e-3)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.22e-1)" "unprognostic (8.06e-3)" 9.1 6.1 3.4 11.7 3.7 22.6 13.9 6.8 3.4 8.8 6.0 7.6 6.8 11.7 8.9 7.1 7.9 7.3 5.0 3.3 3.5 6.0 6.4 7.7 12.6 5.1 4.4 11.1 7.5 5.6 3.1 12.1 3.8 9.3 11.5 6.3 7.8 7.3 5.0 15.6 7.7 9.9 4.0 12.7 7.3 8.3 4.4 14.3 7.4 5.4 16.1 8.5 7.4 6.7 21.5 21.5 39.9 5.0 13.1 18.2 22.8 29.4 19.0 25.9 30.6 39.4 43.3 55.8 47.0 15.3 32.5 40.1 33.7 22.1 34.1 37.5 20.0 48.7 31.5 22.7 6.0 32.7 33.6 12.8 13.4 33.7 21.0 11.7 23.0 26.8 34.9 35.6 20.9 15.5 33.2 30.5 13.0 49.3 23.3 29.0 35.3 28.1 16.8 29.6 14.1 19.8 40.6 26.0 8.6 33.2 43.4 19.3 16.9 38.7 28.6 33.9 21.5 8.8 33.2 54.4 10.4 50.3 31.5 5.7 8.0 6.5 8.2 10.0 8.3 6.4 6.0 8.9 11.6 6.9 5.1 8.4 3.8 8.6 8.4 8.7 8.8 6.7 3.4 3.7 6.8 3.4 3.3 3.5 5.1 4.4 3.8 4.0 4.4 6.7 23.6 28.9 14.3 0.0 6.3 0.0 0.0 0.0 0.0 0.0 12.5 13.7 0.0 0.0 9.3 9.2 0.0 39.2 20.8 0.0 3.9 11.4 0.0 19.5 22.2 8.4 0.0 0.0 0.0 8.1 15.8 8.9 0.0 16.3 17.7 34.1 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 8.8 0.0 0.0 6.1 0.0 0.0 6.5 11.7 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 28.0 7.2 16.8 0.0 0.0 MRTFA "BSAC, KIAA1438, MAL, MKL, MKL1, MRTF-A" ENSG00000196588 "Myocardin related transcription factor A" Q969V6 22 40410281-40636719 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Actin-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 4.5;Cardiomyocytes: 8.7;Cytotrophoblasts: 8.9;Extravillous trophoblasts: 8.7;Fibroblasts: 4.3;Hofbauer cells: 12.7;Syncytiotrophoblasts: 7.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 189.4" "Group enriched" "Detected in all" 5 "dendritic cells: 93.1;granulocytes: 189.4;monocytes: 58.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030782 Approved Supported Nucleoplasm,Cytosol No No "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA030782: AB_10600930" "unprognostic (7.90e-3)" "unprognostic (4.51e-2)" "unprognostic (2.99e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (9.37e-2)" "unprognostic (4.38e-3)" "unprognostic (1.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.35e-2)" "unprognostic (1.51e-1)" "unprognostic (3.74e-2)" "prognostic unfavorable (1.58e-7)" "unprognostic (9.05e-2)" "unprognostic (8.15e-2)" "unprognostic (1.30e-2)" "unprognostic (3.98e-1)" 21.1 15.4 15.8 27.3 18.0 80.7 19.9 10.9 22.8 25.5 12.3 20.8 11.7 33.1 7.3 16.6 22.6 11.7 21.3 20.2 10.0 14.6 12.3 24.5 27.5 9.3 8.7 20.9 16.1 8.9 13.8 18.3 7.9 19.4 8.8 11.1 18.2 15.2 19.1 24.4 18.6 16.3 6.7 29.7 19.1 35.9 9.5 21.7 22.1 8.0 22.8 22.0 19.6 15.3 26.5 33.9 14.5 17.5 21.6 15.9 27.8 25.6 16.6 23.1 22.8 19.1 7.9 27.2 10.2 27.0 20.3 35.5 12.7 31.9 13.8 32.0 29.2 46.3 39.9 24.7 17.8 53.5 79.8 15.5 36.7 22.4 15.1 17.5 18.3 15.0 12.9 12.3 11.5 25.3 20.7 57.4 11.7 14.2 12.1 35.4 17.5 16.4 16.9 22.1 8.7 8.7 43.7 19.4 13.8 18.3 16.0 59.0 27.8 14.7 38.7 21.4 20.9 16.1 16.5 39.1 12.1 25.6 26.5 49.0 53.5 189.4 18.5 43.7 16.9 13.0 15.8 13.6 64.3 18.6 21.1 18.1 57.2 16.8 58.8 93.1 22.0 34.2 15.8 18.0 10.9 22.8 20.2 10.0 9.3 8.7 7.9 6.7 9.5 15.3 4.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 8.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 8.7 4.3 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 7.8 0.6 0.0 0.0 0.0 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSH6 GTBP ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 119.6;Theca cells: 114.9" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" 11.7 22.7 9.3 17.7 13.7 24.0 16.2 15.0 12.7 15.5 12.7 13.0 9.0 27.7 10.2 11.7 17.8 10.9 9.3 8.9 11.5 12.1 19.8 11.6 28.4 12.7 11.7 53.0 31.3 17.0 9.8 20.3 13.0 15.0 12.4 21.6 10.8 15.6 10.5 13.1 9.8 27.2 10.7 12.7 10.9 35.3 11.3 36.3 17.2 11.2 31.0 12.8 12.2 19.9 116.5 77.6 128.4 37.5 42.3 46.3 67.9 63.6 51.1 60.2 59.8 67.2 41.4 158.1 84.5 59.5 82.0 46.0 130.3 74.3 82.1 80.7 69.0 117.0 60.8 71.1 28.8 131.5 37.8 38.6 28.3 60.7 41.6 53.8 40.8 5.3 115.9 69.8 61.8 85.5 144.2 80.1 130.7 81.3 37.7 219.6 204.3 84.7 44.5 76.2 92.8 100.3 79.1 40.4 42.7 124.3 54.6 42.6 33.4 72.2 92.3 54.6 80.6 63.8 79.3 276.2 61.9 77.9 42.4 7.7 3.7 3.8 4.8 6.2 5.5 4.3 5.5 5.0 5.5 4.2 8.4 4.5 2.5 5.9 6.4 2.7 5.3 3.6 9.3 13.7 15.0 12.7 8.9 11.5 12.7 11.7 13.0 10.7 11.3 19.9 19.8 28.9 21.4 5.9 19.2 25.2 22.0 12.3 31.9 25.4 14.4 15.1 8.6 2.8 21.8 7.3 35.5 35.6 20.7 7.4 3.9 15.7 46.4 27.1 31.1 18.4 4.8 47.1 8.5 9.6 21.8 24.0 8.6 31.7 17.7 119.6 13.6 10.2 13.0 15.2 12.1 9.7 20.3 5.6 13.2 17.5 25.4 16.8 3.6 7.5 10.0 22.7 8.2 9.5 27.4 9.1 3.7 22.6 31.1 16.1 2.6 6.7 22.1 31.4 6.6 27.4 33.0 54.3 48.8 22.0 17.5 9.6 19.8 114.9 12.1 11.7 MSI2 ENSG00000153944 "Musashi RNA binding protein 2" Q96DH6 17 57255851-57684689 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 830.2;Cone photoreceptor cells: 754.8;Rod photoreceptor cells: 500.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 184.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022300, HPA068990" Approved Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 14: REH - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB022300: , HPA068990: " "unprognostic (4.73e-2)" "unprognostic (2.28e-1)" "unprognostic (3.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (2.20e-2)" "unprognostic (4.89e-2)" "unprognostic (2.96e-1)" "unprognostic (4.17e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.22e-8)" "prognostic favorable (2.00e-4)" "unprognostic (4.87e-2)" "unprognostic (1.57e-1)" "unprognostic (2.72e-3)" 7.5 69.1 52.2 13.2 52.8 20.2 18.9 53.0 43.4 12.1 105.7 14.1 10.3 14.0 49.9 9.3 22.9 18.3 33.4 42.0 74.6 36.8 7.5 8.3 22.2 82.5 88.6 46.4 12.8 88.6 44.7 22.6 63.4 21.5 15.6 126.0 17.0 21.0 60.7 8.0 11.7 7.6 63.5 17.2 16.6 15.4 58.8 46.5 25.6 43.4 19.6 19.8 8.2 56.0 11.8 18.8 79.0 28.6 7.7 7.8 53.9 13.7 16.4 16.8 10.1 23.6 20.4 56.9 47.1 9.4 13.1 11.8 50.6 18.1 34.8 77.1 31.7 26.2 46.5 58.7 17.8 28.0 23.9 10.4 24.3 2.4 29.9 24.1 19.3 46.6 52.5 42.3 67.6 27.1 136.8 7.2 26.0 64.0 33.2 184.3 109.8 45.5 46.2 84.0 76.6 154.5 22.1 22.9 63.7 33.8 36.9 21.0 22.4 11.2 27.2 9.2 23.0 57.3 51.7 68.8 29.9 16.7 70.2 2.7 0.1 1.9 0.7 0.1 0.6 0.7 0.8 0.7 0.2 0.4 0.6 0.7 0.1 0.8 0.8 1.1 1.6 0.2 52.2 52.8 53.0 43.4 42.0 74.6 82.5 88.6 63.4 63.5 58.8 56.0 20.5 6.4 28.7 830.2 50.5 24.0 74.9 54.5 34.7 202.1 53.2 33.9 99.1 54.3 42.3 75.4 754.8 117.9 37.5 29.5 123.3 49.3 15.3 150.2 30.8 28.1 98.2 35.5 67.6 14.2 25.9 34.2 34.1 70.8 41.8 178.7 29.6 31.5 20.4 294.4 175.5 51.8 109.9 12.6 16.4 27.2 64.7 20.1 39.2 158.3 13.2 220.6 22.6 249.3 111.6 12.8 24.3 77.5 88.8 74.7 11.6 51.2 106.0 500.1 13.1 42.3 30.6 3.1 7.6 28.2 16.1 149.3 50.6 113.5 37.8 92.4 MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 93.4;fallopian tube: 278.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Alveolar cells type 2: 85.6;Club cells: 121.9;Glandular and luminal cells: 57.1;Paneth cells: 214.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 513.4;EFO-21: 77.4;HeLa: 173.4;hTCEpi: 111.5;OE19: 96.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 1.7" "CAB002216, HPA017172" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "CAB002216: AB_563874, HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" 93.4 0.2 0.7 1.1 1.0 3.2 0.5 0.6 1.5 15.9 0.3 8.9 7.1 6.2 24.1 7.1 278.2 16.4 8.4 0.7 0.8 6.5 0.2 71.8 0.2 1.9 1.2 3.7 0.9 0.1 0.7 2.7 1.3 3.8 4.0 0.7 39.3 9.9 0.0 1.4 2.9 3.4 1.0 0.4 13.0 1.1 1.2 0.8 0.2 0.0 27.2 2.9 2.9 1.0 0.4 2.1 0.0 1.0 0.0 0.0 2.3 0.3 7.7 8.7 2.0 7.4 513.4 0.0 77.4 0.7 0.1 1.3 0.0 0.7 0.7 0.2 0.3 0.0 173.4 5.9 4.4 0.2 0.1 0.0 111.5 0.0 2.0 7.8 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.6 96.4 0.8 0.2 0.2 0.6 2.4 0.1 0.1 0.0 29.7 0.1 0.0 0.1 0.7 0.0 0.0 0.4 12.1 0.1 0.0 0.3 0.3 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.3 0.7 1.0 0.6 1.5 0.7 0.8 1.9 1.2 1.3 1.0 1.2 1.0 0.0 189.1 85.6 0.0 0.0 0.3 3.0 49.0 0.0 1.4 0.3 0.3 1.6 52.9 121.9 25.8 0.0 0.2 0.0 4.1 0.0 9.3 1.6 35.8 3.3 0.7 3.0 0.0 0.0 0.9 0.0 4.6 0.0 57.1 0.0 0.0 0.4 0.1 2.9 0.0 0.0 1.6 22.4 1.0 1.9 7.4 4.7 3.7 1.8 1.0 4.4 0.0 0.0 0.0 0.0 33.0 214.4 0.0 1.4 3.3 1.7 0.1 54.2 0.6 0.0 0.0 2.8 0.6 0.7 0.5 0.1 0.1 1.3 0.0 3.1 50.8 MSMB "IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94" ENSG00000263639 "Microseminoprotein beta" P08118 10 46033307-46048180 "Cancer-related genes, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "prostate: 9384.0" "Cell type enriched" "Detected in many" 4 "Prostatic glandular cells: 10715.4" "Cancer enriched" "Detected in many" 42 "prostate cancer: 3435.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 25.6;NB-4: 21.6;RPMI-8226: 11.3;SH-SY5Y: 6.1;SK-BR-3: 5.9;U-2197: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB026357, HPA051257" Enhanced "Secreted in male reproductive system" NA NA 6000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB026357: , HPA051257: AB_2681410" "unprognostic (6.47e-2)" "unprognostic (7.21e-3)" "unprognostic (1.37e-2)" "unprognostic (8.18e-3)" "unprognostic (4.28e-3)" "unprognostic (9.24e-3)" "unprognostic (1.66e-1)" "unprognostic (8.66e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.19e-4)" 5.1 4.5 0.0 3.0 0.0 0.1 20.5 0.0 0.0 3.2 0.0 2.8 10.3 0.3 45.1 12.3 4.6 3.0 0.5 0.0 0.0 1.8 1.8 29.9 0.2 0.0 0.0 0.3 2.3 0.2 0.5 0.6 0.0 9384.0 0.1 0.0 31.9 0.6 0.4 39.7 2.3 0.0 0.0 0.7 552.3 10.1 0.0 1.0 0.7 0.0 10.0 7.2 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 25.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 21.6 0.2 0.0 0.0 0.0 0.0 11.3 0.0 1.6 1.0 6.1 0.0 5.9 0.0 0.2 0.4 0.0 0.0 0.0 0.0 12.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.3 0.0 195.9 586.4 0.0 0.0 6.4 1.3 0.0 4.3 2203.2 0.0 0.0 2.1 0.1 0.3 0.0 0.1 48.9 0.6 0.0 10.7 0.0 0.0 0.1 0.2 0.4 9.5 404.2 0.2 1.3 0.0 0.0 1.2 0.2 0.0 0.0 0.8 419.1 0.0 0.0 78.8 0.3 30.5 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.8 29.6 0.0 0.8 10715.4 0.3 0.0 570.6 0.0 0.0 0.0 271.0 0.5 1.4 0.0 0.4 1.5 14.3 0.0 0.1 192.4 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 213.3 83.3 66.6 259.8 71.4 269.8 144.6 80.0 70.9 113.9 79.6 116.0 43.9 155.8 45.0 87.9 110.0 123.1 130.2 64.8 95.9 139.7 91.8 281.5 207.5 101.9 79.6 91.9 41.0 39.2 48.2 150.6 98.8 72.5 78.4 24.0 76.0 126.6 56.2 100.7 96.6 251.6 91.8 200.0 78.4 21.9 87.3 177.0 152.5 75.7 242.2 154.8 98.0 95.5 298.3 223.2 214.0 177.9 250.6 328.9 1.9 733.9 472.2 397.3 305.5 0.6 50.9 247.7 638.8 654.4 210.3 199.4 228.5 523.4 514.1 461.7 63.0 687.5 355.0 0.6 236.0 845.3 1063.8 248.1 110.7 733.1 641.5 384.2 892.3 338.5 339.5 747.1 638.4 0.6 503.0 631.0 266.1 0.3 418.9 259.8 384.0 189.0 426.5 0.2 1.7 0.8 590.6 4.4 231.5 239.7 2.7 453.8 1426.9 449.5 285.3 613.2 494.6 268.6 438.4 262.5 328.9 1053.3 513.0 219.9 312.4 194.0 214.8 359.3 160.4 91.9 116.9 170.6 225.3 76.9 78.3 121.9 334.3 177.5 460.3 31.9 97.0 673.8 66.6 71.4 80.0 70.9 64.8 95.9 101.9 79.6 98.8 91.8 87.3 95.5 243.4 179.5 163.0 19.9 140.8 205.5 62.2 56.5 38.7 0.7 27.9 30.9 27.5 11.5 45.4 68.0 4.2 6.0 227.3 7.5 29.4 177.3 1.4 35.7 64.9 256.2 0.0 71.9 2.2 170.0 16.0 85.7 16.3 62.9 164.6 22.6 100.3 51.2 167.2 5.0 3.8 3.2 2.0 255.3 206.2 5.3 73.7 251.9 69.4 67.5 291.9 43.6 337.8 7.1 14.7 327.7 3.3 109.4 105.7 102.2 0.0 113.6 25.6 2.4 72.3 85.0 131.0 1.9 3.6 24.3 149.5 4.2 206.9 24.4 2.2 54.0 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 10 "liver: 927.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 362.8" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 84.6;NB-4: 17.3;U-266/70: 21.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024036 Approved "Secreted to blood" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA024036: AB_1854147" "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 29.3 28.0 8.1 1.0 8.3 6.3 8.2 8.8 14.0 12.6 8.1 5.1 50.6 8.9 11.3 7.3 10.5 7.4 4.9 8.1 8.4 96.9 927.9 5.9 3.6 8.4 8.4 12.5 16.4 9.4 29.3 5.8 8.3 12.9 2.1 5.3 8.1 5.1 3.6 14.8 31.1 2.1 8.1 13.9 8.8 34.9 8.2 2.2 36.4 2.9 1.7 6.0 6.9 8.3 0.2 0.4 1.2 2.0 3.7 7.6 3.7 1.1 1.4 0.6 0.8 3.9 1.2 0.3 2.6 1.3 0.5 0.8 0.6 1.5 0.6 1.3 0.7 0.6 2.6 84.6 5.8 0.0 1.6 10.2 2.6 0.7 2.1 14.1 1.4 3.5 0.7 9.9 1.9 0.6 0.5 17.3 0.2 1.1 1.0 0.4 0.5 2.2 4.2 0.6 0.2 2.8 0.0 1.6 0.4 2.5 1.5 5.7 0.9 1.9 0.6 0.1 0.2 21.8 2.9 0.5 2.2 3.2 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 8.3 8.8 14.0 8.1 8.4 8.4 8.4 8.3 8.1 8.2 8.3 3.1 6.4 3.9 10.1 3.5 2.9 4.6 5.8 6.8 8.2 6.1 10.2 2.2 45.8 5.4 27.6 8.4 4.8 1.0 5.1 62.6 6.9 7.6 2.3 3.5 3.4 8.3 29.7 1.1 3.9 19.7 5.2 9.2 3.2 1.3 36.9 10.0 362.8 1.4 1.7 2.0 8.9 6.1 10.7 1.4 2.6 3.1 1.2 3.6 2.8 0.1 8.9 0.0 3.0 2.9 2.1 7.2 1.9 1.6 1.3 57.0 61.9 6.7 6.9 0.0 2.3 10.9 21.8 9.2 2.6 4.7 5.1 2.1 22.8 13.7 3.4 MT1A "MT1, MT1S" ENSG00000205362 "Metallothionein 1A" P04731 16 56638666-56640087 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 488.0;liver: 430.8" "Group enriched" "Detected in many" 6 "Adipocytes: 797.9;Fibroblasts: 244.1;Hepatocytes: 343.8;Skeletal myocytes: 561.9;Smooth muscle cells: 889.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 33.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 18.4;ASC TERT1: 27.9;HHSteC: 19.7;HMC-1: 29.5;hTEC/SVTERT24-B: 80.2;NTERA-2: 40.1" "Low region specificity" "Detected in single" "CAB002161, CAB013056" Approved NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "CAB002161: AB_563878, CAB013056: " "unprognostic (1.36e-1)" "unprognostic (4.91e-3)" "unprognostic (1.22e-1)" "unprognostic (3.30e-1)" "unprognostic (1.26e-3)" "unprognostic (9.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (6.67e-3)" "unprognostic (3.10e-2)" "unprognostic (1.86e-1)" "unprognostic (9.43e-2)" "unprognostic (1.35e-2)" 488.0 64.3 9.8 10.8 12.3 0.0 208.1 9.8 14.1 62.0 8.2 28.9 7.7 13.6 1.3 33.4 68.7 30.2 63.3 9.3 10.7 136.8 430.8 115.2 0.6 10.6 10.8 19.8 90.3 2.1 25.9 0.7 11.7 33.1 13.1 4.4 18.9 2.9 100.0 26.1 23.4 16.9 11.5 3.4 42.9 8.4 10.8 6.1 67.7 6.1 0.7 34.0 22.6 9.7 0.0 6.2 0.0 0.1 18.4 27.9 0.4 1.9 7.9 1.2 1.5 2.3 4.8 0.0 2.4 1.1 0.0 0.5 0.0 0.4 2.9 0.0 0.0 0.0 2.5 9.9 19.7 0.2 29.5 8.2 0.0 80.2 0.0 0.0 7.7 0.0 0.7 0.0 5.5 0.0 0.0 0.1 40.1 0.0 0.0 0.0 0.0 3.6 0.5 0.0 0.3 0.1 0.0 0.3 0.0 0.9 0.0 0.3 6.3 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 9.8 12.3 9.8 14.1 9.3 10.7 10.6 10.8 11.7 11.5 10.8 9.7 797.9 9.6 1.7 0.7 1.8 27.4 11.3 1.9 5.7 0.0 11.7 15.4 5.4 8.6 5.1 0.0 0.0 1.1 1.0 11.1 13.7 2.7 0.1 11.9 6.9 63.2 3.6 29.5 0.0 1.8 12.8 244.1 5.1 23.8 3.8 0.3 15.7 343.8 0.3 0.0 0.0 32.3 0.0 10.4 39.6 0.7 55.0 12.4 33.8 0.0 0.0 0.0 0.0 0.0 0.0 3.0 18.6 12.8 1.2 27.9 86.5 16.1 3.0 0.0 26.3 561.9 889.5 0.0 0.3 2.1 19.5 0.5 6.6 0.4 34.7 13.7 MT1G "MT1, MT1K" ENSG00000125144 "Metallothionein 1G" P13640 16 56666730-56668065 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 3543.0;liver: 6959.4;thyroid gland: 2886.6" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 77919.3" "Group enriched" "Detected in all" 4 "liver cancer: 320.1;ovarian cancer: 106.9;prostate cancer: 103.9;testis cancer: 269.9;thyroid cancer: 369.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "U-937: 1103.8" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.62e-1)" "unprognostic (4.21e-1)" "unprognostic (2.77e-2)" "unprognostic (3.15e-1)" "unprognostic (1.32e-2)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (5.97e-2)" "unprognostic (2.49e-2)" "unprognostic (4.21e-1)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (7.92e-2)" "unprognostic (2.26e-2)" 250.2 21.5 434.9 105.8 515.9 2.9 28.1 469.3 912.6 21.9 396.7 821.1 513.8 8.4 2.4 255.4 75.5 12.0 9.3 430.3 455.6 3543.0 6959.4 49.9 5.6 494.0 474.4 3.2 1806.7 0.3 21.7 2.1 465.6 425.3 516.5 42.6 44.2 5.9 8.4 58.4 1096.4 76.3 431.0 3.9 1262.3 4.0 466.6 0.9 2886.6 0.9 2.6 14.2 25.8 430.1 0.4 0.0 0.0 0.0 0.0 0.0 4.4 8.6 1.7 1.1 0.4 0.0 0.0 0.1 16.2 0.0 0.1 1.8 0.2 1.2 0.9 0.8 0.0 4.3 0.0 3.5 4.5 1.0 0.6 1.7 0.0 11.4 0.0 0.1 0.0 0.0 0.3 1.2 0.7 0.0 3.7 251.3 0.5 0.0 0.0 0.0 0.8 70.8 40.8 0.0 21.8 3.0 0.5 1.3 1.1 10.8 0.0 107.8 0.0 0.0 0.8 1.7 0.3 0.6 1.9 0.6 2.0 1103.8 0.0 0.2 0.3 0.1 0.3 0.3 0.3 0.0 0.4 0.6 0.3 0.0 0.4 0.7 0.0 0.0 0.1 0.1 0.7 0.5 434.9 515.9 469.3 912.6 430.3 455.6 494.0 474.4 465.6 431.0 466.6 430.1 10.6 28.9 8.7 38.5 338.7 57.9 26.0 4.5 46.1 0.0 87.0 116.2 11.7 330.3 9.1 2302.6 0.0 3.9 9.8 3657.8 6849.7 74.4 0.3 2960.7 777.1 49.2 246.7 878.6 0.1 283.4 403.2 50.7 443.9 8167.8 17.2 16.8 310.2 16307.3 26.3 0.0 0.1 3688.0 0.0 379.5 4.9 0.9 23.3 765.6 30.2 2.8 10.6 0.0 2.1 2.0 0.1 339.8 10431.2 2.2 26.3 823.7 8631.3 77919.3 3.9 0.0 0.0 25.1 42.9 0.3 0.8 42.2 77.9 132.7 247.5 4.7 3786.7 21.1 MTA1 ENSG00000182979 "Metastasis associated 1" Q13330 14 105419820-105470729 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004508, HPA005544" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm Cytosol "CAB004508: AB_627969, HPA005544: AB_1079420" "unprognostic (6.79e-3)" "unprognostic (4.22e-2)" "unprognostic (1.06e-1)" "unprognostic (6.36e-2)" "unprognostic (2.91e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (6.59e-2)" "unprognostic (1.47e-1)" "unprognostic (6.72e-3)" "prognostic favorable (9.48e-5)" "unprognostic (4.57e-3)" "unprognostic (1.39e-2)" "unprognostic (2.88e-2)" "unprognostic (1.48e-1)" "unprognostic (1.75e-1)" "unprognostic (1.18e-1)" 23.1 23.8 24.1 10.8 23.4 15.4 24.6 23.7 31.0 31.7 19.4 31.2 13.1 29.9 11.6 22.6 31.8 6.2 39.2 24.1 20.1 24.7 24.1 19.6 12.1 22.2 21.5 38.6 30.1 9.4 36.9 9.2 20.1 31.8 5.6 8.3 23.6 12.7 25.6 21.1 22.1 9.0 20.0 26.7 22.5 37.6 22.5 16.5 30.4 7.7 9.1 29.2 24.4 22.3 33.6 26.3 47.9 48.2 18.0 30.5 42.3 26.2 19.9 25.4 24.3 34.4 44.1 65.4 26.7 19.3 17.9 45.3 35.1 25.0 17.1 43.2 59.0 34.1 25.2 35.5 39.6 43.2 25.3 34.4 30.9 18.0 41.1 35.5 36.4 48.0 39.3 27.7 13.4 60.4 78.3 85.2 69.1 47.7 55.1 73.1 29.1 21.5 20.6 26.0 76.9 80.1 35.5 40.5 40.8 24.3 36.7 40.7 26.6 20.4 21.6 34.1 27.8 55.9 28.9 41.3 25.6 28.7 36.6 0.1 0.2 0.8 0.3 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.3 0.4 0.0 0.4 0.1 0.9 0.2 0.2 24.1 23.4 23.7 31.0 24.1 20.1 22.2 21.5 20.1 20.0 22.5 22.3 32.1 3.2 16.0 37.9 20.9 15.6 28.8 14.6 13.1 0.0 64.8 38.6 9.2 27.1 15.2 35.0 0.0 11.6 17.7 17.2 17.6 13.2 32.8 25.0 28.4 20.4 18.6 25.4 17.2 19.6 8.0 21.8 28.1 23.9 5.7 47.6 18.2 15.5 11.0 0.0 16.1 21.6 10.2 18.5 13.5 11.3 36.1 15.7 12.4 21.5 13.8 0.0 20.6 32.6 27.0 16.3 11.5 32.0 17.8 45.4 18.5 8.8 27.0 0.0 19.7 30.5 25.4 21.5 13.3 16.8 19.0 9.3 18.7 27.1 24.9 46.2 MTCP1 "P13MTCP1, p8MTCP1, TCL1C" ENSG00000214827 "Mature T cell proliferation 1" P56278 X 155064034-155147937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Respiratory ciliated cells: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 13.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA032040 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA032040: AB_2674122" "unprognostic (2.42e-2)" "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (6.29e-3)" "unprognostic (8.30e-2)" "unprognostic (4.10e-1)" "unprognostic (2.40e-5)" "unprognostic (9.30e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-2)" "unprognostic (5.72e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (4.52e-8)" "unprognostic (1.55e-3)" "unprognostic (1.06e-2)" "unprognostic (1.39e-2)" "unprognostic (1.75e-2)" 1.0 2.1 0.8 1.9 1.1 2.8 1.8 1.7 1.4 1.3 1.1 1.6 2.0 1.7 2.7 1.2 1.4 1.3 1.4 0.8 1.0 1.8 2.5 1.2 2.5 1.1 0.9 2.3 2.6 1.0 1.7 1.0 1.0 1.7 2.0 2.5 1.6 1.4 1.2 4.2 1.8 1.4 0.9 1.9 2.0 5.3 1.0 1.9 1.9 0.7 2.5 1.4 0.9 1.2 1.2 3.9 1.9 3.1 1.2 1.0 2.1 2.4 1.2 1.5 3.7 3.5 6.0 2.2 2.4 0.5 2.4 3.9 2.6 2.8 1.9 1.5 2.5 1.0 13.6 1.9 1.1 2.4 2.5 1.9 1.3 2.5 2.4 1.8 1.4 3.8 0.9 3.9 1.1 1.7 3.2 5.1 0.9 1.5 0.6 3.4 2.0 5.1 2.0 1.7 0.9 1.4 1.7 1.0 1.7 1.3 1.8 1.1 1.5 1.8 3.0 1.7 1.9 8.6 4.1 4.4 3.4 2.9 2.6 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.8 1.1 1.7 1.4 0.8 1.0 1.1 0.9 1.0 0.9 1.0 1.2 0.5 0.0 1.5 0.0 0.5 0.3 0.3 0.7 0.6 0.0 0.6 0.5 1.4 1.5 1.4 0.0 0.0 0.2 0.8 0.6 0.0 0.8 0.0 0.7 0.3 0.5 1.8 3.2 0.0 1.2 0.4 0.6 0.0 0.6 0.0 2.2 0.4 2.0 0.4 0.0 0.0 0.0 0.0 1.0 0.3 0.6 1.2 0.8 1.8 0.0 1.0 0.0 1.0 0.0 0.0 1.0 0.2 0.4 0.9 0.3 0.3 0.3 2.4 0.0 0.0 0.6 0.4 0.6 0.2 0.4 0.9 0.3 0.7 0.8 0.5 0.1 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262551 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "CAB069425: , HPA071227: AB_2686367" "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favorable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 16.3 19.4 18.2 13.5 19.0 14.0 16.8 18.4 20.1 15.2 18.6 22.8 11.0 17.5 21.8 18.3 14.6 9.0 23.6 19.7 17.7 24.1 27.6 15.2 15.3 16.5 21.2 14.2 18.3 20.6 21.8 11.8 18.4 19.8 16.0 26.9 16.5 13.8 36.4 17.1 19.6 13.8 14.6 21.2 18.7 33.8 22.7 19.2 17.8 17.8 15.9 17.1 14.9 18.7 28.5 25.2 33.3 25.4 39.4 18.6 16.6 23.4 22.3 30.6 29.9 26.0 25.5 31.4 19.6 27.8 18.8 33.1 45.3 35.8 39.3 25.2 33.2 41.7 53.8 33.4 24.7 41.1 29.7 24.0 26.8 43.7 44.0 14.5 39.3 29.6 47.4 26.1 21.6 32.4 28.5 31.2 25.3 29.6 23.5 28.2 39.2 21.0 27.2 25.3 33.4 24.5 50.1 26.8 31.2 36.5 21.8 24.0 42.3 26.5 23.9 20.5 31.8 25.5 25.5 60.5 19.1 43.6 28.6 0.3 1.1 1.3 1.9 2.4 1.6 1.4 1.1 1.0 1.6 1.1 1.3 1.1 0.8 1.1 1.3 1.2 2.4 1.0 18.2 19.0 18.4 20.1 19.7 17.7 16.5 21.2 18.4 14.6 22.7 18.7 9.2 16.0 11.8 40.8 10.0 3.4 5.2 7.6 8.6 0.0 7.7 7.5 25.1 2.8 10.3 9.2 0.0 7.9 9.8 9.4 1.9 8.5 42.0 13.8 16.1 11.0 10.3 14.3 43.8 6.2 7.2 9.2 16.8 18.6 13.3 12.9 5.3 13.4 6.9 0.0 49.2 7.8 6.1 8.2 4.1 36.1 7.8 9.1 8.8 36.5 9.2 0.0 10.3 38.2 37.4 10.4 5.4 8.2 17.2 8.9 7.0 4.5 6.3 0.0 39.5 11.4 12.1 49.3 37.4 15.6 5.7 9.9 9.8 15.3 10.0 5.7 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MUC17 ENSG00000169876 "Mucin 17, cell surface associated" Q685J3 7 101020072-101058859 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 62 "intestine: 42.7" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 320.9" "Cancer enhanced" "Detected in some" "stomach cancer: 22.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031634 Enhanced "Intracellular and membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 45: Enterocytes - Digestion" "HPA031634: AB_10603021" "unprognostic (2.37e-2)" "unprognostic (2.41e-1)" "unprognostic (8.17e-3)" "unprognostic (5.57e-3)" "unprognostic (6.07e-2)" "unprognostic (8.79e-8)" "unprognostic (1.28e-1)" "unprognostic (2.47e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 42.7 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 39.8 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 22.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.9 14.8 0.0 0.0 0.1 320.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 22.0 0.0 MUTYH MYH ENSG00000132781 "MutY DNA glycosylase" Q9UIF7 1 45329163-45340893 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA008732 Uncertain Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA008732: AB_1854219" "unprognostic (6.30e-3)" "unprognostic (7.12e-2)" "unprognostic (6.29e-2)" "unprognostic (8.80e-2)" "unprognostic (3.43e-1)" "unprognostic (5.16e-3)" "prognostic unfavorable (4.76e-8)" "unprognostic (2.80e-2)" "unprognostic (7.12e-3)" "unprognostic (3.05e-2)" "unprognostic (7.80e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.25e-5)" "unprognostic (3.50e-3)" "unprognostic (1.62e-1)" "unprognostic (5.57e-2)" "unprognostic (5.49e-3)" 5.0 5.0 11.9 5.5 12.7 6.7 5.3 16.7 15.6 7.6 10.6 6.0 6.4 6.3 4.6 5.1 5.7 4.2 4.0 11.6 11.9 7.0 5.9 4.4 7.7 12.8 12.4 7.3 5.1 5.1 5.9 6.4 12.7 5.8 5.6 4.9 4.5 5.0 5.6 5.9 6.1 3.6 11.7 7.8 5.8 3.3 12.2 9.8 6.6 4.7 7.0 5.9 5.8 14.4 7.9 6.9 15.5 10.5 11.3 8.4 26.6 5.7 7.4 11.8 9.2 14.3 11.2 22.5 9.0 3.6 9.5 11.3 8.7 11.0 5.4 18.1 7.0 10.2 11.4 10.5 10.0 9.4 7.1 4.6 10.3 16.0 25.7 3.1 8.6 28.6 17.5 7.4 5.0 13.3 27.3 8.7 39.6 19.5 7.9 36.2 12.6 12.3 6.1 14.6 14.5 11.8 11.3 8.7 18.2 20.1 6.7 11.1 4.9 8.3 6.2 7.2 8.2 11.6 14.6 13.3 8.0 14.6 7.5 1.6 7.0 2.9 11.5 11.8 17.2 8.1 11.8 11.5 8.1 8.0 12.7 12.2 1.4 8.8 9.1 6.5 13.4 8.6 11.9 12.7 16.7 15.6 11.6 11.9 12.8 12.4 12.7 11.7 12.2 14.4 10.0 0.0 5.6 17.0 12.1 6.9 10.7 8.1 6.2 15.6 6.7 8.8 3.2 1.5 6.9 7.3 2.1 40.2 8.8 16.5 3.9 6.5 0.9 3.2 5.1 7.6 7.8 6.7 4.0 5.3 14.3 7.5 16.8 3.2 10.8 8.4 5.7 4.3 10.0 5.0 7.0 15.1 12.2 4.0 10.2 1.6 10.8 5.6 7.2 8.4 8.2 12.0 10.3 11.6 12.7 3.8 16.4 12.0 7.5 9.5 12.9 12.2 8.6 20.1 13.1 8.7 7.6 10.5 11.2 5.2 5.4 22.2 13.9 9.5 13.5 8.0 MVP "LRP, VAULT1" ENSG00000013364 "Major vault protein" Q14764 16 29820394-29848039 "Cancer-related genes, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" Ribonucleoprotein "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 504.7;Exocrine glandular cells: 310.8;Paneth cells: 338.3;Proximal enterocytes: 514.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 429.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002321, CAB002752, CAB022717, HPA064740" Enhanced Supported Cytosol NA NA 110000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB002752: , CAB022717: , HPA002321: AB_1079277, HPA064740: AB_2685342" "prognostic favorable (4.51e-4)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (8.17e-2)" "unprognostic (3.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.22e-2)" "unprognostic (6.03e-3)" "unprognostic (2.19e-1)" "unprognostic (6.85e-3)" "unprognostic (2.86e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.22e-1)" "unprognostic (5.19e-2)" "unprognostic (5.69e-3)" "unprognostic (2.65e-2)" 84.4 181.7 26.2 96.0 35.7 46.4 71.0 29.9 33.7 76.6 32.5 165.6 154.7 73.1 14.3 75.4 73.3 74.3 64.4 26.0 31.9 113.4 66.9 121.9 71.1 43.1 36.4 103.3 101.9 18.9 47.5 38.0 35.5 59.7 96.5 6.3 77.1 38.9 50.6 61.1 158.9 69.0 32.6 114.0 107.8 39.4 42.3 31.3 60.6 32.4 47.6 80.0 72.9 38.3 64.8 191.8 0.8 1.7 212.0 275.0 25.9 163.4 258.5 88.0 121.4 24.7 216.8 3.1 134.9 231.0 108.9 78.1 0.8 129.5 42.2 166.4 1.8 3.0 81.6 87.6 190.1 2.3 60.2 366.9 96.1 207.0 58.3 170.5 274.5 6.2 0.5 92.1 167.7 18.3 0.8 4.3 2.4 93.4 11.6 2.1 0.7 32.5 229.1 114.6 10.5 7.6 41.8 53.8 31.8 6.5 9.5 18.7 429.3 124.2 59.4 119.9 62.0 66.6 45.1 2.7 294.6 4.8 24.9 50.4 140.8 56.3 70.9 214.3 55.1 36.6 80.7 73.6 113.1 27.2 59.4 54.0 160.0 73.7 204.0 69.2 90.7 164.4 26.2 35.7 29.9 33.7 26.0 31.9 43.1 36.4 35.5 32.6 42.3 38.3 34.2 48.1 115.5 9.8 31.2 19.6 39.3 120.3 16.5 4.8 17.9 10.0 12.9 82.9 112.0 69.9 2.1 113.6 31.2 504.7 45.0 272.7 4.9 43.9 25.9 40.9 56.5 8.6 3.2 310.8 71.4 52.8 120.8 65.9 33.7 14.8 36.4 23.8 78.0 8.4 3.4 177.1 95.6 41.0 27.1 21.1 57.5 55.0 32.0 9.4 223.3 3.0 59.8 0.0 23.1 278.5 338.3 47.8 36.4 25.0 514.8 194.8 110.3 4.9 19.7 23.8 51.3 2.7 1.8 20.7 21.9 264.5 45.1 24.7 206.8 56.7 MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 264.7;Oligodendrocytes: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 108.2;SK-MEL-30: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: AB_10670588, HPA035320: , HPA056762: AB_2683229" "unprognostic (1.77e-2)" "unprognostic (2.02e-1)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-2)" "unprognostic (1.59e-1)" "unprognostic (9.26e-3)" "prognostic unfavorable (9.17e-4)" "prognostic unfavorable (1.02e-5)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" 34.0 32.7 86.8 13.2 98.0 68.0 45.1 92.9 106.1 38.8 67.0 55.9 24.4 45.6 36.2 52.3 42.4 32.8 63.2 84.9 91.1 39.2 51.1 26.4 13.8 93.9 91.8 81.4 44.7 50.6 22.1 28.5 94.7 41.0 35.0 80.2 80.1 52.1 47.3 47.6 29.6 29.8 89.3 14.8 28.0 23.3 94.9 31.2 54.5 53.2 12.3 34.6 41.2 110.8 18.2 8.3 18.0 39.6 30.7 21.4 7.4 11.1 39.2 7.1 23.1 3.2 33.5 24.6 17.6 20.0 11.3 24.3 23.5 27.8 20.0 13.5 30.9 7.3 15.7 14.5 19.5 14.3 14.4 21.7 96.0 12.4 55.2 108.2 7.1 17.5 26.9 54.9 11.3 12.3 10.1 26.1 7.7 31.0 21.2 6.1 26.0 39.9 22.8 1.6 34.3 52.4 11.1 7.3 167.1 23.3 9.9 42.2 7.7 13.5 21.0 13.6 5.6 44.6 26.1 10.0 34.3 46.1 12.7 1.8 2.7 9.7 2.7 2.3 5.1 3.9 5.1 2.8 1.6 3.6 7.7 1.9 5.6 1.4 5.0 1.7 4.8 2.0 86.8 98.0 92.9 106.1 84.9 91.1 93.9 91.8 94.7 89.3 94.9 110.8 28.9 16.0 16.8 139.1 27.9 58.0 57.9 22.8 51.2 49.9 67.2 66.8 80.2 41.5 27.6 33.1 47.9 5.4 23.0 160.7 46.9 19.3 5.1 29.1 36.4 34.1 16.9 264.7 60.8 14.8 20.1 36.0 15.8 37.3 3.8 19.1 27.8 56.6 11.1 52.2 102.5 20.1 18.3 24.1 20.5 8.8 45.1 22.6 104.9 30.9 29.9 144.2 9.2 131.7 214.9 10.4 52.5 55.7 22.5 73.4 57.0 67.1 25.3 46.0 46.0 69.6 63.0 23.8 28.2 37.4 67.3 9.7 36.9 27.4 16.6 36.9 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MYB c-myb ENSG00000118513 "MYB proto-oncogene, transcription factor" P10242 6 135181308-135219173 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 35.2;breast: 20.1;intestine: 26.5;lymphoid tissue: 66.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 47.8;Erythroid cells: 83.2;granulocytes: 26.0;Intestinal goblet cells: 32.7;Ionocytes: 26.4;Respiratory ciliated cells: 37.2;Undifferentiated cells: 52.0" "Group enriched" "Detected in many" 5 "breast cancer: 17.7;colorectal cancer: 16.4;stomach cancer: 5.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 4.6;eosinophil: 5.4;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 5.4" "Cell line enhanced" "Detected in many" "HL-60: 219.8;MOLT-4: 403.1;NB-4: 208.5;REH: 244.9;THP-1: 343.8;U-937: 186.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017704, HPA071605" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB017704: , HPA071605: " "unprognostic (1.69e-1)" "unprognostic (5.82e-2)" "unprognostic (1.82e-3)" "unprognostic (1.37e-2)" "unprognostic (4.06e-1)" "unprognostic (8.35e-3)" "unprognostic (1.13e-3)" "unprognostic (2.48e-2)" "unprognostic (6.44e-2)" "unprognostic (1.00e-1)" "unprognostic (3.71e-2)" "prognostic favorable (9.65e-4)" "unprognostic (2.41e-11)" "prognostic favorable (9.87e-4)" "unprognostic (8.35e-2)" "unprognostic (3.04e-2)" "unprognostic (9.40e-2)" 0.3 0.5 1.6 5.3 1.7 35.2 20.1 0.0 0.7 1.6 0.4 25.3 10.9 1.0 0.1 3.0 8.4 0.9 0.1 0.3 0.2 0.1 0.4 2.0 6.3 0.9 1.0 0.0 0.3 3.6 0.0 0.4 0.6 1.4 26.5 0.3 0.6 0.9 0.1 3.0 9.4 1.4 0.2 1.2 2.0 0.7 0.3 66.1 0.1 0.0 7.0 1.1 1.3 0.1 1.8 0.3 1.9 3.0 0.0 0.1 0.3 1.0 0.6 1.1 1.1 0.3 1.4 10.9 0.4 0.3 0.4 0.9 5.6 0.0 0.7 18.0 2.5 138.8 1.0 0.5 0.1 219.8 105.1 0.0 0.1 0.6 0.0 0.5 0.3 133.4 114.6 20.1 1.1 11.6 403.1 208.5 1.5 19.2 1.7 244.9 5.9 33.2 0.3 1.5 10.5 6.9 0.5 10.4 0.6 0.5 7.9 343.8 0.4 0.3 1.6 7.9 2.4 27.7 7.7 66.0 0.1 186.1 2.3 4.6 0.7 5.4 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.4 0.2 1.6 1.7 0.0 0.7 0.3 0.2 0.9 1.0 0.6 0.2 0.3 0.1 0.2 0.0 1.3 0.0 2.3 2.7 1.3 1.3 0.6 0.9 47.8 12.6 0.4 2.8 7.1 0.0 0.0 1.4 9.1 18.1 0.0 0.0 0.1 24.3 0.3 0.3 17.6 83.2 0.6 0.8 0.4 0.5 4.6 2.2 26.0 0.4 0.0 0.0 1.1 0.0 2.7 32.7 26.4 1.2 1.7 0.2 0.0 2.1 8.8 0.0 2.8 0.9 0.0 0.0 0.2 0.1 10.2 0.0 4.6 2.1 2.3 0.0 37.2 0.0 0.0 0.6 0.9 0.0 1.8 10.2 7.0 0.3 3.6 0.1 52.0 2.2 MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716495 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;lymphoid tissue: 55.5" "Cell type enhanced" "Detected in many" "B-cells: 33.0;dendritic cells: 32.6;Erythroid cells: 82.3;Extravillous trophoblasts: 32.3;Plasma cells: 139.6;Spermatogonia: 33.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 295.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 91.5" "Lineage enriched" "Detected in many" 34 "dendritic cells: 91.5" "Cell line enhanced" "Detected in many" "MCF7: 763.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB017114: , HPA030530: AB_2673515, HPA055416: AB_2682811" "unprognostic (9.75e-3)" "unprognostic (1.29e-2)" "unprognostic (3.20e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.66e-3)" "unprognostic (9.23e-3)" "unprognostic (1.78e-1)" "unprognostic (2.38e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" 1.6 0.6 0.1 24.2 0.1 91.8 1.6 0.1 0.2 1.1 0.2 8.6 7.0 1.4 0.1 10.1 0.4 1.0 0.4 0.1 0.1 0.6 1.1 1.8 55.5 0.1 0.1 0.3 11.2 0.1 0.2 5.7 0.1 0.5 6.9 0.0 1.6 0.2 0.1 4.2 7.8 2.1 0.1 27.8 6.1 15.6 0.4 33.3 0.5 0.0 53.5 3.5 2.5 0.1 195.8 121.8 105.4 109.6 1.0 3.5 136.2 87.0 29.0 265.6 194.6 600.2 118.8 393.6 49.2 37.8 55.8 116.1 192.1 59.6 98.8 74.2 124.1 183.2 118.7 164.2 0.2 168.6 121.7 2.4 5.1 101.6 22.9 5.9 72.2 189.6 188.1 470.3 23.8 763.7 346.0 236.3 121.8 155.4 105.4 237.3 216.3 222.1 49.6 39.7 96.7 140.6 255.6 253.3 26.1 110.4 167.2 183.1 34.0 16.3 264.3 118.3 151.5 162.1 363.8 606.5 34.2 142.3 103.9 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.2 0.0 91.5 1.3 0.8 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.2 0.0 0.0 0.0 33.0 4.2 0.8 0.8 0.0 0.0 2.5 3.4 2.0 1.5 0.1 0.0 0.0 14.4 32.6 3.4 0.0 0.4 5.9 0.9 1.3 1.8 0.0 82.3 0.4 0.9 32.3 4.8 10.2 2.9 0.0 18.9 0.7 1.4 13.5 0.0 0.3 5.1 0.0 2.4 2.6 14.1 0.0 3.2 1.8 0.0 0.0 0.0 1.0 0.0 0.5 0.7 1.1 0.0 139.6 0.3 0.5 0.0 0.0 0.0 0.0 0.1 3.9 7.0 33.6 8.2 2.4 3.7 3.0 1.2 8.6 2.4 MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 254.6;skin 1: 289.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1013.3;Basal prostatic cells: 1080.5;Basal squamous epithelial cells: 1270.8;Squamous epithelial cells: 768.8;Suprabasal keratinocytes: 1070.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 1069.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" 254.6 59.8 2.6 62.3 2.2 53.7 115.8 3.7 3.3 54.4 3.0 57.9 30.6 53.8 3.8 99.5 167.5 83.3 45.5 2.3 6.3 20.0 64.9 47.0 49.4 9.2 5.0 100.0 103.1 7.0 12.3 33.4 6.0 32.7 36.8 0.7 42.2 14.1 50.6 289.1 48.6 54.8 4.5 60.1 70.6 12.5 5.5 47.2 27.0 15.7 39.2 63.2 96.3 4.4 56.8 89.3 9.3 100.9 166.6 209.8 28.4 72.2 31.6 87.5 72.7 137.0 150.2 587.3 86.4 43.0 82.4 122.2 383.8 226.5 67.8 128.9 167.0 370.7 189.5 203.6 150.0 282.0 52.0 138.8 560.4 55.5 490.8 74.8 104.3 217.3 549.8 315.5 49.7 151.9 394.4 616.9 27.4 273.2 204.0 203.7 46.1 1069.6 79.2 61.9 660.7 64.9 32.6 270.7 195.9 17.5 106.4 172.2 120.5 63.4 71.6 49.7 87.2 5.5 8.7 275.9 55.3 286.2 30.8 3.0 39.5 0.7 31.5 36.0 161.5 92.0 114.3 67.4 33.5 71.4 195.2 128.0 4.1 85.5 26.9 1.4 95.6 88.9 2.6 2.2 3.7 3.3 2.3 6.3 9.2 5.0 6.0 4.5 5.5 4.4 218.0 57.7 70.4 0.7 108.0 1013.3 1080.5 278.9 1270.8 0.6 251.3 207.3 10.9 44.3 98.4 12.9 0.0 20.6 20.9 23.0 1.9 78.3 1.0 43.9 224.5 158.0 12.5 189.1 1.6 43.6 61.2 337.9 46.4 72.0 57.0 47.6 141.0 25.8 26.9 0.0 1.1 67.8 97.6 43.7 133.1 3.9 98.8 23.3 168.9 1.0 17.0 1.4 5.2 0.0 0.2 66.5 40.4 67.4 45.7 364.8 4.8 13.3 21.5 0.3 46.0 458.5 349.1 0.6 0.6 768.8 1070.1 5.9 75.0 56.0 117.7 409.4 MYCL "bHLHe38, LMYC, MYCL1" ENSG00000116990 "MYCL proto-oncogene, bHLH transcription factor" P12524 1 39895426-39902256 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 67.8;skin 1: 41.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 34.9;Hepatocytes: 24.3;Intestinal goblet cells: 25.0;monocytes: 27.4;Squamous epithelial cells: 34.2;Urothelial cells: 27.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 28.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8" "Group enriched" "Detected in many" 72 "dendritic cells: 22.8;monocytes: 17.3" "Group enriched" "Detected in many" 7 "U-266/70: 444.0;U-266/84: 364.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA063132, HPA074515" Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Mitotic chromosome" "HPA063132: AB_2684946, HPA074515: " "unprognostic (7.45e-2)" "unprognostic (6.91e-2)" "unprognostic (7.36e-2)" "unprognostic (1.83e-3)" "unprognostic (1.61e-2)" "unprognostic (2.92e-3)" "unprognostic (6.72e-3)" "prognostic favorable (4.49e-4)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-3)" "unprognostic (2.75e-2)" "unprognostic (5.21e-2)" "unprognostic (1.53e-2)" "unprognostic (5.80e-2)" 0.8 0.3 1.8 4.7 2.0 0.6 3.3 1.2 2.0 5.2 1.8 6.1 4.8 0.9 7.2 22.1 3.1 1.5 0.5 2.2 1.7 1.5 11.4 3.3 6.4 1.5 1.5 0.3 67.8 0.3 2.9 6.7 1.6 4.2 6.7 0.2 6.4 7.5 0.5 41.5 5.7 1.1 1.9 7.6 6.2 1.3 2.0 6.5 5.3 0.5 9.5 15.9 12.8 1.6 1.2 0.4 14.4 3.5 0.2 0.1 31.8 0.5 0.2 1.0 0.7 0.4 0.8 2.2 1.4 0.1 0.4 3.3 10.4 2.7 0.8 2.0 4.9 0.5 0.3 0.5 0.4 0.3 7.5 1.0 12.1 0.4 1.3 0.2 1.2 5.4 3.2 0.4 0.6 1.2 0.2 0.3 13.4 2.2 0.4 1.3 15.5 2.9 1.1 58.0 2.5 3.1 1.4 2.1 0.8 5.5 3.7 18.7 0.0 0.0 4.6 6.2 0.5 444.0 364.6 1.0 0.1 2.3 0.3 0.0 17.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.2 0.0 3.4 22.8 0.0 6.7 1.8 2.0 1.2 2.0 2.2 1.7 1.5 1.5 1.6 1.9 2.0 1.6 0.4 0.0 1.1 0.0 0.8 6.6 10.0 2.1 13.1 0.4 3.8 6.0 3.7 0.0 5.5 9.2 0.0 34.9 20.1 13.4 0.0 1.5 0.1 5.1 0.6 0.5 17.3 0.0 0.2 5.8 15.4 0.9 5.1 6.3 0.0 0.0 1.4 24.3 5.1 0.0 0.3 25.0 8.2 8.3 13.1 0.4 0.0 10.6 1.8 0.0 27.4 0.8 0.0 1.0 0.0 2.9 6.5 0.0 3.6 5.3 6.4 0.1 4.9 0.1 0.0 1.4 0.7 0.0 1.2 34.2 11.8 17.5 0.3 0.0 10.8 27.1 MYCN "bHLHe37, MYCNOT, N-myc, NMYC" ENSG00000134323 "MYCN proto-oncogene, bHLH transcription factor" P04198 2 15940550-15947007 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 9.5" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 84.2;Granulosa cells: 26.4" "Cancer enriched" "Detected in many" 5 "testis cancer: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057420 Approved Nucleoplasm,Nucleoli NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA057420: AB_2683434" "unprognostic (8.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-2)" "unprognostic (4.11e-1)" "unprognostic (2.46e-2)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" "unprognostic (1.12e-3)" "unprognostic (8.89e-2)" "unprognostic (2.47e-1)" "unprognostic (4.90e-2)" "unprognostic (1.23e-1)" 0.4 0.8 3.5 0.6 3.5 0.9 0.4 3.1 3.9 1.5 0.8 0.6 1.6 0.9 0.1 0.7 0.5 0.3 1.2 3.4 3.0 3.3 0.8 0.7 1.6 4.4 3.9 5.1 0.2 0.1 0.3 9.5 3.7 0.1 0.5 1.0 4.7 0.2 0.4 1.4 0.9 0.3 3.3 0.3 4.6 3.6 3.5 2.9 2.9 0.7 1.2 0.5 0.4 5.9 0.0 0.0 44.1 0.0 0.0 0.0 239.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 4.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.8 0.4 0.2 91.3 2.1 0.0 0.0 63.3 12.8 0.0 3.1 1.0 16.0 0.0 0.1 0.0 40.9 0.1 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.5 3.1 3.9 3.4 3.0 4.4 3.9 3.7 3.3 3.5 5.9 0.8 0.0 0.0 0.7 0.0 0.5 0.1 0.0 0.0 2.6 0.1 0.9 0.7 0.0 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 1.2 0.5 0.1 2.7 0.0 4.2 2.0 0.0 84.2 1.0 2.6 0.8 0.0 26.4 0.0 0.6 2.4 0.0 4.2 0.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.1 1.0 0.0 10.1 7.5 0.3 1.1 0.4 0.0 0.0 0.4 3.2 0.0 0.2 0.0 4.2 0.7 1.3 3.7 0.3 0.0 11.5 0.0 9.4 0.3 0.0 MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 172.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" 20.1 14.2 6.9 43.5 7.4 51.8 15.0 7.2 7.5 15.2 8.0 30.3 32.2 12.1 18.6 36.6 14.4 23.5 9.4 6.7 7.7 13.7 61.1 42.6 35.2 9.5 7.5 11.4 11.6 11.6 9.2 22.6 8.0 14.3 31.7 2.1 18.0 12.0 3.2 17.7 32.2 24.5 8.6 40.7 27.6 7.7 9.2 38.3 9.4 8.8 41.6 47.4 20.3 8.5 25.1 34.2 5.9 33.2 25.0 32.0 10.8 23.6 39.0 68.1 72.9 22.7 30.9 52.8 13.8 44.7 15.8 30.9 43.2 24.2 22.1 39.5 8.7 28.5 16.6 36.6 21.4 36.2 72.0 38.4 26.6 39.2 15.3 13.2 39.9 40.3 13.3 22.3 36.8 25.7 61.3 12.2 22.1 52.8 35.7 24.8 7.0 23.1 37.6 58.9 3.0 12.0 33.4 172.1 22.3 4.8 25.8 40.8 35.5 13.8 7.9 60.6 24.0 28.9 32.9 38.5 25.0 63.0 28.9 288.5 236.9 296.9 67.2 333.6 58.1 43.7 60.6 69.3 203.6 35.2 42.1 59.5 284.7 54.6 436.1 99.9 87.4 257.3 6.9 7.4 7.2 7.5 6.7 7.7 9.5 7.5 8.0 8.6 9.2 8.5 13.4 6.4 15.2 2.0 19.5 14.4 13.5 12.7 14.2 1.0 11.3 10.8 1.6 5.7 16.4 5.5 0.0 14.6 35.3 40.8 7.9 24.5 1.4 10.9 30.2 15.9 9.6 9.7 0.2 27.3 24.4 10.8 23.9 18.6 24.1 10.0 10.4 33.2 32.2 0.0 0.4 14.9 10.2 75.4 40.5 0.9 13.7 61.5 3.6 1.9 58.1 4.1 28.8 2.5 0.3 64.0 34.8 10.5 12.9 16.0 28.0 12.2 12.1 0.1 13.1 4.3 7.2 8.6 0.6 15.1 17.2 12.0 19.6 10.2 15.9 49.4 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 MYO5A "GS1, MYH12, MYO5, MYR12" ENSG00000197535 "Myosin VA" Q9Y4I1 15 52307283-52529050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.1;parathyroid gland: 47.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 353.0;Inhibitory neurons: 241.0;Oligodendrocyte precursor cells: 330.8;Oligodendrocytes: 404.2" "Cancer enhanced" "Detected in all" "melanoma: 25.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 201.0;RPMI-8226: 140.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001356 Enhanced Approved "Focal adhesion sites,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites, Centriolar satellite" "HPA001356: AB_1079441" "unprognostic (1.54e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-2)" "unprognostic (2.29e-2)" "unprognostic (1.97e-2)" "unprognostic (3.91e-2)" "unprognostic (2.30e-2)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "unprognostic (4.74e-2)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (5.63e-3)" "unprognostic (3.79e-3)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (4.22e-4)" 10.3 8.3 17.0 12.1 20.8 21.8 6.5 3.0 39.1 6.8 0.0 6.1 3.8 5.0 3.7 5.3 4.0 8.5 5.8 19.0 3.6 5.3 2.9 8.8 15.0 9.6 4.2 5.7 5.2 47.4 8.9 6.3 9.8 5.1 5.9 26.1 5.2 3.5 5.4 11.8 5.0 9.4 0.0 9.5 4.7 5.9 6.6 11.0 8.4 5.0 13.1 9.7 5.3 20.8 19.5 33.7 17.6 21.3 16.2 19.3 19.0 34.7 31.1 18.1 14.0 3.2 7.8 18.7 8.9 41.8 26.5 15.7 40.7 35.6 22.3 105.5 9.6 16.7 8.8 4.2 8.3 9.0 16.3 13.0 21.9 26.6 52.4 17.6 106.8 12.0 0.7 201.0 34.8 34.4 8.2 1.2 8.1 0.5 26.6 14.5 27.8 140.8 15.1 14.0 12.7 7.8 32.3 26.2 59.4 13.1 14.0 9.1 52.0 36.4 15.7 17.1 34.1 20.9 49.9 22.0 39.4 25.1 53.5 0.4 2.4 3.1 1.4 1.7 2.1 1.1 1.3 0.9 2.7 0.7 0.2 0.4 3.0 0.3 1.4 1.5 2.2 1.1 17.0 20.8 3.0 39.1 19.0 3.6 9.6 4.2 9.8 0.0 6.6 20.8 11.2 12.8 11.4 68.2 19.8 20.8 9.3 10.5 7.4 75.1 6.7 5.5 12.1 2.8 19.8 14.7 39.6 0.6 18.4 0.3 0.0 5.4 18.0 9.3 8.0 12.7 1.2 2.5 353.0 6.3 0.4 7.5 3.1 6.7 22.8 5.0 2.5 1.3 24.4 26.9 241.0 0.2 2.0 27.1 28.0 10.8 3.7 50.2 97.8 52.5 36.7 6.0 15.5 330.8 404.2 6.1 2.5 1.9 32.4 10.2 0.0 2.8 11.1 28.7 6.6 16.7 10.8 14.0 9.4 3.9 11.6 1.1 23.7 2.1 0.3 7.3 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MYOD1 "bHLHc1, MYF3, MYOD, PUM" ENSG00000129152 "Myogenic differentiation 1" P15172 11 17719571-17722136 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 36.1" "Group enriched" "Detected in some" 9 "Skeletal myocytes: 10.0;Spermatogonia: 3.8" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "RH-30: 461.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA055436, HPA078647" Enhanced Nucleoplasm NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "HPA055436: , HPA078647: " "unprognostic (1.07e-3)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.5 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 461.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.3 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MYOG "bHLHc3, MYF4" ENSG00000122180 Myogenin P15173 1 203083129-203086012 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "skeletal muscle: 101.0;tongue: 46.7" "Cell type enriched" "Detected in single" 36 "Skeletal myocytes: 11.0" "Group enriched" "Detected in some" 6 "head and neck cancer: 3.9;testis cancer: 1.7" "Region enriched" "Detected in single" 5 "cerebellum: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 222 "HSkMC: 29.6;RH-30: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA028336 Supported Nucleoplasm NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "HPA028336: AB_2672562" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (2.22e-1)" "unprognostic (2.79e-9)" "unprognostic (3.96e-1)" "unprognostic (2.56e-1)" 0.0 0.0 0.4 0.0 0.2 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 2.2 0.0 0.2 4.1 0.0 101.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.6 0.0 46.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 57.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.0 0.4 0.2 2.5 0.4 0.5 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 NAB2 MADER ENSG00000166886 "NGFI-A binding protein 2" Q15742 12 57089043-57095476 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 98.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004510, HPA027464" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "CAB004510: AB_627982, HPA027464: AB_10601138" "prognostic favorable (7.41e-4)" "unprognostic (4.04e-2)" "unprognostic (2.20e-3)" "unprognostic (2.43e-2)" "unprognostic (4.74e-2)" "unprognostic (2.10e-1)" "unprognostic (1.88e-3)" "unprognostic (1.80e-1)" "unprognostic (5.85e-2)" "unprognostic (1.19e-1)" "unprognostic (2.13e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.38e-6)" "unprognostic (1.95e-1)" "unprognostic (9.76e-2)" "unprognostic (5.67e-3)" "unprognostic (6.19e-3)" 21.8 16.1 25.2 9.9 26.8 6.8 14.2 30.3 31.0 33.7 24.0 29.8 10.1 32.3 21.0 24.5 31.0 17.4 20.5 28.3 25.0 20.1 22.3 24.0 12.0 23.2 23.1 51.1 10.2 19.5 35.4 11.1 22.1 25.4 5.0 10.7 11.6 16.6 7.6 33.4 15.7 13.4 21.6 16.9 15.9 16.8 25.4 17.4 20.7 9.9 10.4 27.7 33.8 24.8 15.2 9.8 49.2 45.2 43.3 56.7 5.5 44.1 40.8 28.0 23.1 15.6 8.7 9.6 17.6 44.4 8.1 27.0 16.9 34.0 14.3 4.0 4.5 11.4 8.1 16.6 33.2 9.1 26.5 64.4 36.1 32.6 10.9 43.7 7.5 7.2 26.5 9.6 32.4 73.4 14.0 44.5 9.9 12.9 16.6 10.4 64.1 5.1 11.8 6.0 5.5 13.1 21.9 12.5 98.3 12.3 28.0 20.0 8.4 40.7 34.1 28.8 13.2 22.7 6.0 5.1 39.5 5.9 25.1 0.0 1.1 0.2 0.5 2.7 0.6 0.9 0.9 0.7 0.6 2.3 1.1 1.1 0.4 0.4 2.9 0.0 1.0 0.6 25.2 26.8 30.3 31.0 28.3 25.0 23.2 23.1 22.1 21.6 25.4 24.8 7.6 12.8 13.0 5.9 11.6 29.6 19.5 23.4 39.3 20.3 17.3 13.8 2.9 2.8 13.6 9.2 2.1 3.7 4.9 1.1 7.9 7.4 0.6 22.9 21.2 13.7 6.6 4.8 11.4 1.4 10.5 19.7 8.6 25.4 17.1 7.8 18.2 17.1 11.2 10.1 5.4 1.1 10.2 16.3 43.7 2.9 19.6 14.3 21.4 8.4 1.6 7.9 1.0 1.0 1.9 4.1 0.0 18.8 8.7 12.9 8.7 5.6 5.9 4.4 19.7 9.8 16.3 2.6 18.7 23.4 32.5 56.2 10.7 2.5 1.5 8.6 NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058334-42070842 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 65.0;Hofbauer cells: 91.6;Kupffer cells: 64.4;monocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 202.5;intermediate monocyte: 249.1;myeloid DC: 195.2;non-classical monocyte: 257.9;plasmacytoid DC: 119.8" "Group enriched" "Detected in all" 6 "dendritic cells: 195.2;monocytes: 257.9" "Cell line enhanced" "Detected in all" "HMC-1: 190.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA000649: AB_1079448" "unprognostic (3.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (1.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (3.68e-2)" "unprognostic (1.92e-3)" "unprognostic (8.95e-2)" "unprognostic (2.53e-1)" 21.4 12.7 9.3 32.3 10.4 20.1 13.4 10.3 10.1 20.6 17.0 26.1 20.4 17.2 12.4 17.2 20.0 22.1 16.0 8.9 11.5 14.9 31.9 27.1 20.8 13.9 10.8 17.0 11.4 39.2 11.7 42.8 12.6 18.2 26.7 7.7 17.3 18.6 7.7 13.4 24.2 28.3 12.2 20.3 16.6 9.0 12.0 13.9 15.1 12.3 19.0 24.8 13.7 14.4 27.8 14.0 21.7 38.9 37.0 41.9 15.9 22.4 45.7 37.9 39.2 31.4 39.9 13.5 13.5 49.1 22.9 19.2 16.7 27.4 22.3 31.0 21.2 33.5 20.1 21.5 21.5 28.1 190.4 28.9 23.8 34.0 14.4 19.5 63.4 11.6 12.4 56.0 30.2 32.3 10.4 11.5 5.8 25.3 18.5 23.0 11.0 24.2 29.4 32.7 6.7 7.7 29.8 27.0 29.3 19.1 40.4 50.9 34.4 26.6 31.8 17.1 20.7 30.9 33.3 10.9 28.3 52.7 33.4 36.5 202.5 25.1 13.6 249.1 13.8 10.5 14.1 12.7 195.2 6.9 9.2 8.4 9.9 18.8 257.9 119.8 18.3 121.0 9.3 10.4 10.3 10.1 8.9 11.5 13.9 10.8 12.6 12.2 12.0 14.4 6.5 9.6 6.7 4.6 8.2 3.3 9.4 10.9 5.7 2.8 6.7 6.2 4.2 4.3 11.3 7.3 8.4 46.1 11.0 27.3 3.9 15.4 15.8 5.6 8.8 11.2 6.0 12.4 1.1 8.1 65.0 13.8 6.1 10.2 9.5 3.2 9.3 33.6 91.6 0.0 2.0 15.0 6.1 64.4 36.3 17.9 7.2 52.5 19.6 12.2 65.8 5.9 6.2 0.5 2.0 13.0 23.9 6.8 22.2 6.0 40.0 9.8 15.7 6.4 19.7 6.1 10.0 10.7 5.2 7.1 3.4 58.3 6.9 6.5 15.4 10.0 NAIP "BIRC1, NLRB1" ENSG00000249437 "NLR family apoptosis inhibitory protein" Q13075 5 70968166-71025339 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 31.6" "Cell type enhanced" "Detected in many" "Kupffer cells: 138.4;Macrophages: 97.4;Microglial cells: 113.4;Oligodendrocytes: 177.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 8.4;myeloid DC: 5.3" "Group enriched" "Detected in many" 16 "dendritic cells: 5.3;granulocytes: 4.4;monocytes: 8.4" "Cell line enhanced" "Detected in some" "MOLT-4: 3.9;SiHa: 2.1;T-47d: 2.3" HPA042438 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA042438: AB_10796578" "unprognostic (9.03e-2)" "unprognostic (6.03e-2)" "unprognostic (1.31e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "unprognostic (1.12e-3)" "unprognostic (1.12e-1)" "unprognostic (2.23e-2)" "unprognostic (4.36e-2)" "unprognostic (1.86e-1)" "unprognostic (2.54e-2)" "unprognostic (5.13e-1)" "unprognostic (1.69e-3)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (1.38e-1)" "unprognostic (9.96e-2)" 5.5 2.7 1.1 2.7 0.8 1.6 3.4 1.8 1.7 3.0 1.0 3.2 0.3 2.1 0.8 1.4 4.5 1.1 2.9 1.0 0.8 2.7 3.4 6.8 2.4 0.8 0.5 2.9 3.3 0.2 1.4 0.6 1.0 2.2 0.5 2.1 1.8 0.5 1.0 2.2 4.6 0.8 0.5 31.6 2.8 4.1 1.2 0.4 3.6 0.0 0.2 3.0 2.7 1.0 0.0 0.0 0.6 0.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.5 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.4 0.5 0.7 0.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.3 0.4 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.2 0.1 0.4 0.0 2.1 0.0 0.1 0.4 2.3 0.0 0.0 0.6 0.2 0.1 0.0 0.5 0.0 0.3 0.1 0.1 0.4 0.2 8.4 0.0 0.2 2.0 0.1 0.0 0.0 0.1 5.3 0.2 0.2 0.1 4.4 0.3 0.4 0.3 0.1 2.5 1.1 0.8 1.8 1.7 1.0 0.8 0.8 0.5 1.0 0.5 1.2 1.0 8.5 19.2 9.7 60.7 9.4 3.6 2.4 2.2 2.8 16.2 10.2 4.6 3.2 11.5 8.2 5.5 22.9 3.7 7.3 4.1 0.0 1.9 44.0 10.0 15.1 11.1 10.7 18.3 50.2 2.3 2.4 8.2 14.3 10.9 5.1 15.8 9.3 7.3 69.3 16.8 46.4 5.6 2.0 138.4 16.4 11.6 10.8 97.4 1.8 113.4 44.2 6.7 4.1 67.8 177.5 1.6 2.5 7.2 9.8 2.3 1.6 1.3 6.9 38.4 6.6 12.8 5.5 13.7 4.4 3.6 3.8 2.9 8.5 6.0 4.0 1.5 NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248298-106285966 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 580.0;Langerhans cells: 1123.7;Macrophages: 947.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 279.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 279.2" "Cell line enhanced" "Detected in all" "HHSteC: 387.5;U-87 MG: 434.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" NA NA 2140000 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Cell Junctions" "CAB034349: AB_2251220, HPA047776: AB_2680151, HPA057722: " "unprognostic (2.87e-1)" "prognostic unfavorable (4.78e-4)" "unprognostic (5.90e-3)" "unprognostic (1.63e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (8.81e-4)" "unprognostic (2.15e-1)" "unprognostic (2.74e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (3.02e-1)" "prognostic unfavorable (2.49e-6)" "unprognostic (6.83e-2)" "unprognostic (6.96e-2)" "unprognostic (7.76e-2)" "unprognostic (6.44e-3)" 308.5 74.2 14.4 360.5 15.6 312.5 103.3 15.2 35.4 47.3 21.7 62.5 38.5 38.6 6.9 228.2 107.6 113.7 103.1 15.2 20.9 82.9 317.9 218.5 23.2 75.7 24.9 58.4 80.9 25.9 30.1 87.3 30.3 70.1 30.3 17.2 126.0 13.4 135.9 54.1 55.9 48.0 21.3 88.2 102.4 11.7 46.3 15.6 42.2 44.4 39.9 283.3 86.7 21.5 103.6 41.0 14.6 16.8 85.8 95.0 34.4 26.1 194.7 57.0 90.6 25.7 38.7 77.7 78.8 32.1 131.5 58.2 38.8 88.1 93.8 50.5 51.7 35.8 17.2 22.6 387.5 61.3 49.4 94.8 94.2 114.9 115.0 70.6 187.3 32.0 70.5 225.6 68.1 49.4 58.1 19.4 36.6 33.6 59.7 25.8 30.4 147.6 46.2 60.8 33.4 19.3 46.0 61.1 107.9 43.0 25.4 9.4 168.2 75.6 52.9 105.9 51.9 212.1 142.7 115.7 434.3 69.3 105.6 39.6 6.5 16.0 1.8 21.8 2.4 3.9 2.2 2.7 7.0 3.4 2.8 2.2 279.2 4.4 30.5 5.5 7.1 4.8 14.4 15.6 15.2 35.4 15.2 20.9 75.7 24.9 30.3 21.3 46.3 21.5 323.8 131.4 245.7 12.1 78.0 207.6 321.0 105.7 169.0 23.8 184.2 132.0 94.8 197.3 161.4 42.3 12.5 26.2 67.5 105.8 46.9 320.6 12.2 128.0 160.8 192.8 25.1 29.5 25.3 141.3 58.9 239.6 132.0 296.5 188.4 18.8 159.5 580.0 107.0 40.4 28.8 51.9 63.1 390.3 1123.7 6.9 40.4 947.3 161.9 46.9 102.7 22.6 9.2 12.1 22.4 138.1 49.7 31.2 93.7 364.0 112.8 50.7 94.1 30.8 26.3 264.6 185.6 30.5 65.8 98.3 207.8 25.3 110.3 38.4 79.4 334.5 NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391282-18401218 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "intestine: 33.5;liver: 128.6" "Group enriched" "Detected in some" 4 "Distal enterocytes: 14.8;Hepatocytes: 59.0;Paneth cells: 15.9;Proximal enterocytes: 36.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.0;RT4: 1.6;SCLC-21H: 2.2;SK-BR-3: 1.4" HPA043704 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 2: Hepatocytes - Metabolism" "HPA043704: AB_2678625" "unprognostic (2.74e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.61e-5)" "unprognostic (1.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" 0.1 0.1 0.2 1.6 0.2 0.0 1.1 0.2 0.6 0.5 0.1 15.0 33.5 0.9 0.7 0.1 0.2 0.2 0.2 0.2 0.2 1.9 128.6 0.2 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.6 0.1 0.4 13.2 0.0 0.0 0.5 0.0 0.0 25.6 1.6 0.2 1.3 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.0 1.0 1.6 2.2 0.0 0.0 1.4 0.0 0.1 0.3 0.2 0.5 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 1.0 0.0 14.8 5.9 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.4 59.0 0.2 0.0 0.0 7.4 0.0 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.9 2.6 0.0 0.0 36.0 0.8 0.3 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 4.4 0.1 0.8 6.7 0.1 NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 882.1;Excitatory neurons: 1473.6;Inhibitory neurons: 753.8;Microglial cells: 534.0;Oligodendrocyte precursor cells: 786.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.0;THP-1: 41.8;U-138 MG: 30.8;WM-115: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" 3.8 4.8 9.7 1.0 15.0 0.5 4.0 0.9 17.3 1.2 0.0 1.7 0.3 2.0 2.9 1.9 2.2 5.1 1.9 13.6 0.0 0.4 1.0 3.3 0.6 0.7 0.4 18.3 0.5 0.4 3.1 2.2 0.0 2.1 0.8 5.2 0.9 2.5 1.3 2.6 0.6 2.5 1.4 8.0 0.8 2.8 1.6 1.9 1.2 3.4 0.4 3.3 1.7 10.3 3.5 8.7 0.6 0.2 8.5 18.1 0.3 26.5 20.9 10.7 5.3 1.7 0.6 0.2 1.9 22.0 7.2 2.5 7.8 4.0 19.3 0.1 0.2 0.2 3.9 0.2 6.7 0.1 0.2 6.2 0.2 47.0 11.1 9.3 16.4 0.1 0.0 0.1 26.2 0.5 0.2 12.0 2.7 0.3 2.1 1.0 2.1 0.0 1.7 0.1 0.6 0.0 1.6 0.3 3.5 0.8 0.1 41.8 14.1 30.8 8.1 12.0 18.2 1.2 0.0 0.7 8.8 0.5 38.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 9.7 15.0 0.9 17.3 13.6 0.0 0.7 0.4 0.0 1.4 1.6 10.3 11.1 19.2 10.0 882.1 0.0 3.6 8.4 0.2 0.0 5.0 3.8 3.8 3.4 0.0 7.5 0.0 0.0 0.1 0.0 0.2 0.0 4.2 10.4 4.2 8.2 5.6 16.4 0.0 1473.6 1.6 0.1 18.7 0.5 10.3 11.4 0.8 3.9 0.0 7.3 50.5 753.8 0.0 0.0 0.0 3.7 4.7 23.9 1.4 12.4 534.0 0.1 18.3 0.0 786.1 144.1 19.2 0.0 7.5 1.2 18.0 0.0 0.3 8.7 2.0 0.0 28.8 5.3 0.3 0.8 0.2 1.4 0.3 1.3 73.7 0.0 2.9 NBN "AT-V1, AT-V2, ATV, NBS, NBS1" ENSG00000104320 Nibrin O60934 8 89933331-90003228 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 265.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001429, CAB003836" Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Nucleoplasm "CAB003836: AB_562172, HPA001429: AB_1854460" "unprognostic (1.52e-1)" "unprognostic (1.72e-1)" "unprognostic (2.32e-3)" "unprognostic (7.46e-2)" "unprognostic (2.49e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (5.05e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.15e-1)" "unprognostic (6.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.28e-1)" "unprognostic (2.84e-2)" "unprognostic (1.03e-1)" 22.5 12.4 9.2 27.8 12.8 54.0 25.4 9.3 10.0 16.9 7.4 18.3 15.1 22.3 11.4 20.0 14.5 22.5 12.1 10.2 12.5 20.7 22.3 18.1 24.3 10.7 8.6 16.9 15.5 15.4 9.0 14.1 9.9 17.5 22.5 9.8 16.6 14.9 10.0 10.3 16.0 24.2 11.0 23.4 12.7 16.4 11.0 19.0 22.7 16.2 26.4 21.8 9.6 15.0 54.8 30.1 29.3 15.6 16.5 38.7 18.9 37.9 49.5 46.6 50.8 17.2 41.8 83.8 42.2 35.5 19.1 17.7 35.7 35.7 59.8 38.0 19.7 67.7 16.8 23.6 30.8 40.0 35.2 30.5 18.3 27.2 57.9 22.8 39.5 33.9 50.6 46.6 55.3 46.9 65.6 26.0 8.5 39.5 31.4 42.3 25.3 47.0 62.8 73.8 8.1 26.6 23.5 265.1 23.1 16.3 49.8 31.4 29.2 40.9 28.0 25.5 38.0 21.2 25.0 45.5 41.3 39.4 39.1 32.4 17.7 32.9 11.9 19.7 12.7 15.2 8.5 8.8 18.9 8.9 8.1 9.0 34.4 16.1 31.5 10.4 5.9 13.1 9.2 12.8 9.3 10.0 10.2 12.5 10.7 8.6 9.9 11.0 11.0 15.0 36.9 48.1 14.2 24.5 39.8 11.9 13.5 20.4 23.9 25.4 29.7 22.9 30.3 14.3 33.7 27.6 2.1 23.0 29.3 11.2 43.0 35.1 17.6 45.4 46.9 22.9 12.1 31.7 45.0 32.0 19.7 36.3 19.9 31.2 79.7 38.3 18.9 30.6 25.9 13.5 39.9 16.9 16.2 29.2 27.1 7.2 19.0 51.1 12.4 32.8 54.7 29.4 36.0 40.7 40.3 24.7 9.9 26.4 38.8 11.6 9.9 40.5 36.4 11.2 6.6 50.3 31.7 20.2 46.0 31.5 13.5 10.8 35.3 68.7 19.4 11.0 NBPF1 "FLJ20719, KIAA1693" ENSG00000219481 "NBPF member 1" Q3BBV0 1 16562319-16613562 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 73.8;Distal enterocytes: 66.4;Oligodendrocyte precursor cells: 68.3;Oligodendrocytes: 87.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Microtubules,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Microtubules "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (8.16e-3)" "unprognostic (6.96e-2)" "unprognostic (1.33e-2)" "unprognostic (6.09e-2)" "unprognostic (3.49e-1)" "unprognostic (4.76e-2)" "unprognostic (1.15e-5)" "unprognostic (2.16e-2)" "unprognostic (5.40e-2)" "unprognostic (2.99e-1)" "unprognostic (4.90e-2)" "unprognostic (2.14e-2)" "prognostic favorable (1.06e-4)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.68e-1)" 8.8 32.6 4.0 2.5 5.1 2.0 9.5 5.0 4.3 16.4 2.7 14.9 3.5 10.6 2.5 6.4 10.7 3.3 6.1 3.2 4.5 9.0 8.2 6.2 1.3 5.3 4.8 18.1 7.4 6.0 9.0 4.6 5.1 9.9 5.3 2.9 9.3 4.2 5.5 7.2 13.6 5.7 4.6 8.2 8.8 23.0 5.0 1.7 7.2 2.6 1.8 13.6 11.0 6.0 6.1 8.6 8.4 5.1 2.3 2.7 1.5 4.1 5.4 7.7 6.8 3.1 2.4 4.8 1.2 11.7 3.0 5.5 3.9 2.5 8.9 3.0 4.5 1.5 3.0 3.0 3.7 2.4 3.6 2.9 3.1 11.1 3.2 4.0 3.5 10.9 5.2 2.6 3.0 4.7 10.5 1.8 1.6 1.1 16.3 8.9 4.6 0.5 2.2 1.2 10.4 10.3 10.6 4.3 5.8 2.4 6.6 1.7 4.1 6.7 3.6 9.2 3.6 1.3 6.7 2.7 1.5 3.5 2.8 0.1 0.1 1.3 0.3 0.2 0.4 0.3 0.3 0.4 0.1 0.5 0.3 0.4 0.0 0.1 0.3 0.2 0.0 0.1 4.0 5.1 5.0 4.3 3.2 4.5 5.3 4.8 5.1 4.6 5.0 6.0 5.2 16.0 14.8 73.8 5.7 8.2 3.0 10.9 29.0 7.5 8.4 8.6 14.5 8.6 11.6 11.0 8.4 6.3 3.5 66.4 3.9 5.5 10.4 4.4 8.2 10.2 3.0 5.9 33.6 3.5 7.9 19.7 12.2 3.1 6.3 17.1 3.6 6.1 12.8 10.1 52.1 25.4 12.2 6.6 15.9 6.9 6.8 7.1 8.8 47.8 4.4 5.0 9.2 68.3 87.9 6.1 19.3 7.2 5.3 3.8 24.0 10.8 15.5 6.5 6.6 7.9 10.0 52.5 24.3 14.7 7.7 3.1 4.0 43.2 15.2 3.1 NBPF10 AG1 ENSG00000271425 "NBPF member 10" 1 146064711-146229000 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 46.1;Basal keratinocytes: 57.0;Langerhans cells: 100.9;Suprabasal keratinocytes: 105.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA038748, HPA042595, HPA043105, HPA043692, HPA044023, HPA046971, HPA058050" Approved Approved Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Microtubules "HPA038748: AB_2676188, HPA042595: , HPA043105: AB_2678318, HPA043692: , HPA044023: AB_2678779, HPA046971: AB_2679883, HPA058050: " "unprognostic (2.05e-1)" "unprognostic (8.84e-2)" "unprognostic (5.84e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-1)" "unprognostic (5.16e-3)" "unprognostic (3.26e-1)" "unprognostic (2.17e-1)" "unprognostic (9.49e-2)" "unprognostic (6.64e-5)" "unprognostic (1.60e-1)" "unprognostic (6.01e-2)" "unprognostic (1.11e-3)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (9.61e-2)" "unprognostic (6.68e-2)" 3.7 1.1 3.4 2.8 2.8 7.6 4.3 2.2 6.4 4.9 7.4 2.8 1.1 3.5 3.8 2.8 3.0 2.2 1.3 3.6 2.2 1.9 3.2 3.3 2.5 3.8 3.1 5.4 3.3 3.2 0.3 2.5 2.9 2.7 2.8 4.6 2.0 3.0 1.0 7.4 1.2 3.4 1.7 4.4 1.8 3.3 4.5 2.7 2.3 2.2 2.4 2.2 1.4 4.1 6.4 1.7 3.6 2.4 11.3 13.6 3.0 3.3 4.5 3.3 3.3 1.5 3.0 2.7 0.7 6.4 3.2 3.0 4.0 4.5 6.7 3.4 3.0 6.3 5.0 0.8 4.5 2.7 1.9 12.4 4.1 9.2 8.8 10.6 3.9 1.7 2.0 8.7 7.1 7.3 1.1 2.4 1.5 1.6 4.7 1.4 2.6 3.6 2.3 4.5 0.4 0.4 5.1 4.9 1.8 5.8 4.2 3.6 12.3 3.2 2.9 2.9 4.4 5.8 2.3 3.4 2.9 2.9 2.7 2.2 2.0 2.7 0.3 1.0 0.4 1.5 0.3 0.3 0.8 1.5 0.3 0.2 5.6 0.3 2.3 2.2 0.3 0.1 3.4 2.8 2.2 6.4 3.6 2.2 3.8 3.1 2.9 1.7 4.5 4.1 0.5 76.9 46.1 13.7 12.8 57.0 4.9 15.4 5.2 0.5 3.7 2.0 8.4 2.8 22.0 0.0 0.0 0.7 9.2 1.5 0.0 5.3 15.1 2.8 2.8 3.4 0.0 10.5 0.8 2.7 5.0 18.2 3.1 6.1 20.2 6.4 0.7 1.8 1.4 0.0 1.1 2.7 14.2 5.0 100.9 3.3 6.5 17.7 30.2 4.7 14.2 2.0 9.2 5.0 0.1 5.5 25.3 8.2 5.7 2.1 2.2 0.2 19.6 2.0 0.0 7.6 9.9 9.9 5.4 23.8 105.8 0.5 6.6 1.4 3.4 4.5 NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 290.1;heart muscle: 145.5" "Cell type enhanced" "Detected in many" "Astrocytes: 530.8;Excitatory neurons: 461.4;Inhibitory neurons: 441.2;Oligodendrocyte precursor cells: 939.0;Oligodendrocytes: 1013.5" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.7" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.7" "Cell line enhanced" "Detected in many" "HEL: 61.3;RH-30: 132.5;SCLC-21H: 107.4;SH-SY5Y: 52.7;U-138 MG: 72.8;WM-115: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 1200000 2300000000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" 4.6 65.7 124.0 3.9 169.1 1.5 2.7 118.1 140.3 35.1 0.0 47.8 4.6 62.7 3.5 7.0 40.4 4.8 145.5 135.6 179.1 3.2 2.9 1.8 1.3 140.4 134.2 43.8 2.6 0.0 22.2 0.5 147.4 14.9 6.6 117.7 3.6 17.7 31.2 2.1 18.3 46.9 129.7 4.7 23.0 5.0 137.0 0.4 30.2 29.5 1.0 34.8 24.3 290.1 0.1 0.0 20.8 0.3 0.2 0.5 0.3 1.0 0.0 0.7 1.2 0.3 0.3 3.1 18.2 20.1 0.8 0.3 0.1 0.0 0.0 0.4 12.1 61.3 0.1 0.0 2.1 0.0 9.5 12.4 0.1 0.1 18.6 0.1 0.0 0.1 0.0 1.0 20.8 0.0 0.2 5.2 1.8 0.0 0.4 0.1 132.5 10.0 0.0 0.0 107.4 52.7 0.1 0.5 0.1 2.0 0.2 0.8 0.2 72.8 33.4 0.3 31.8 0.1 0.5 0.1 8.3 28.4 79.0 0.0 0.2 0.0 3.6 0.0 1.2 0.0 0.1 0.5 0.1 0.0 0.0 1.4 0.7 53.7 0.0 0.0 0.2 1.9 124.0 169.1 118.1 140.3 135.6 179.1 140.4 134.2 147.4 129.7 137.0 290.1 13.7 0.0 0.0 530.8 0.4 1.7 0.5 0.0 0.0 123.5 5.7 0.6 131.7 0.0 0.0 0.0 37.5 0.6 27.7 0.1 1.9 18.3 6.7 0.3 2.4 2.8 5.4 0.0 461.4 0.0 0.2 12.8 5.1 0.5 1.3 11.7 7.1 0.7 0.4 175.0 441.2 0.0 8.2 4.7 3.8 5.9 15.2 1.8 0.0 35.6 1.2 216.6 59.8 939.0 1013.5 1.3 0.0 10.1 5.6 0.4 0.0 0.2 0.7 98.0 0.0 107.5 4.8 1.0 2.8 0.4 1.7 0.1 13.4 5.6 0.0 0.2 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 467.5;Excitatory neurons: 313.0;Inhibitory neurons: 421.8;Microglial cells: 341.9;Oligodendrocyte precursor cells: 459.4;Oligodendrocytes: 305.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 81.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: AB_2686235, HPA070520: AB_2686276" "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 16.6 15.1 24.0 13.3 25.4 17.3 17.3 24.6 28.2 18.6 13.6 15.9 20.9 19.0 12.8 17.6 15.7 14.0 15.3 29.6 19.5 18.9 15.0 16.0 15.3 17.7 19.2 26.6 17.4 30.0 16.6 17.1 16.0 15.2 16.6 47.3 16.0 20.2 33.4 15.7 18.9 19.0 19.5 16.3 12.5 19.9 21.8 26.1 11.8 36.1 16.3 14.9 15.5 22.3 14.1 10.3 17.7 9.2 19.2 17.3 26.9 7.4 14.7 9.1 8.1 9.6 5.9 10.2 3.1 13.5 17.4 3.4 10.7 6.3 9.8 48.6 15.5 36.5 4.1 4.1 12.0 16.9 29.1 27.9 9.4 8.8 7.1 11.3 9.4 12.9 22.6 16.5 14.0 9.4 15.1 6.0 8.5 8.2 6.8 11.8 81.5 5.1 9.9 18.9 16.2 12.8 17.1 10.2 7.4 9.3 12.3 8.6 10.2 15.2 11.9 10.5 7.5 18.8 17.5 17.2 8.6 10.5 7.7 10.6 3.3 7.0 3.4 2.6 3.8 1.6 3.0 3.8 2.5 2.4 2.9 3.5 13.8 3.5 2.9 5.2 3.7 2.0 24.0 25.4 24.6 28.2 29.6 19.5 17.7 19.2 16.0 19.5 21.8 22.3 41.0 38.5 31.5 467.5 16.7 30.5 11.6 7.8 14.2 96.5 32.3 26.7 41.9 17.2 22.8 14.7 52.1 13.1 47.0 39.0 7.9 16.5 29.7 14.6 37.6 34.9 25.2 29.9 313.0 26.6 18.1 39.8 19.9 28.4 20.2 52.9 36.8 22.8 17.9 62.2 421.8 20.7 20.3 29.8 30.3 7.4 47.2 37.7 19.6 341.9 34.7 66.7 78.2 459.4 305.8 20.1 33.5 43.2 14.3 15.7 30.4 12.5 16.9 71.6 39.5 116.9 34.4 37.7 37.6 16.6 31.0 5.3 33.4 27.2 24.1 21.7 NCOA2 "bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2" ENSG00000140396 "Nuclear receptor coactivator 2" Q15596 8 70109782-70403808 "Cancer-related genes, Disease related genes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 161.6;Excitatory neurons: 158.9;Inhibitory neurons: 314.8;Microglial cells: 233.3;Oligodendrocyte precursor cells: 249.8;Oligodendrocytes: 186.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060243 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear bodies" "HPA060243: AB_2684229" "unprognostic (9.79e-3)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.91e-2)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (6.77e-2)" "unprognostic (2.06e-1)" "unprognostic (7.00e-2)" "unprognostic (2.20e-2)" "unprognostic (2.63e-2)" "prognostic favorable (5.08e-4)" "unprognostic (2.52e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" 8.4 8.9 8.9 9.9 10.5 23.3 13.4 8.9 10.0 10.0 1.5 10.6 11.6 10.1 29.6 15.3 10.9 8.9 15.0 13.6 13.2 14.4 23.8 10.0 11.6 8.0 6.8 16.2 7.3 15.2 7.3 12.1 7.7 12.9 10.6 26.1 11.3 12.1 8.3 10.5 12.1 9.0 4.6 12.4 10.9 14.7 9.9 15.3 12.1 15.9 12.5 10.0 9.9 6.1 13.7 16.9 18.2 10.3 16.2 16.5 18.6 7.8 7.8 5.9 5.5 8.6 15.6 16.3 3.1 14.3 9.7 8.0 22.5 10.7 6.5 38.7 17.9 28.5 8.5 13.8 8.5 5.8 7.2 14.5 11.7 7.9 11.3 9.2 4.0 11.7 9.2 24.0 6.9 13.7 14.5 5.8 9.6 15.7 7.9 14.1 7.6 10.3 9.3 22.5 13.8 10.2 13.4 7.1 11.0 12.7 16.7 10.5 5.3 8.4 10.6 10.8 4.2 31.5 17.3 15.4 8.6 7.6 12.5 3.1 1.6 2.2 2.2 2.3 1.5 1.3 1.3 1.9 1.5 2.1 1.5 1.6 5.7 1.4 5.2 0.6 2.0 1.2 8.9 10.5 8.9 10.0 13.6 13.2 8.0 6.8 7.7 4.6 9.9 6.1 20.9 12.8 25.1 161.6 27.3 16.2 8.6 10.8 17.6 25.8 29.5 17.5 34.1 28.6 25.8 25.8 52.1 22.1 26.9 30.8 11.7 9.3 6.4 23.6 26.4 17.7 25.2 28.8 158.9 12.4 12.5 21.6 21.4 38.0 22.2 23.2 22.1 65.9 17.4 74.0 314.8 17.4 10.2 46.8 17.8 7.6 19.9 28.1 21.4 233.3 23.1 14.3 19.6 249.8 186.0 12.8 14.8 22.2 49.9 15.5 22.7 17.6 19.0 33.4 26.3 22.5 20.2 13.3 16.5 18.8 21.5 31.7 36.6 10.9 17.0 15.8 NCOA3 "ACTR, AIB1, bHLHe42, CAGH16, KAT13B, p/CIP, RAC3, SRC-3, SRC3, TNRC16, TRAM-1" ENSG00000124151 "Nuclear receptor coactivator 3" Q9Y6Q9 20 47501887-47656877 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 155.8;Plasma cells: 168.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 187.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009800, HPA024210" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "CAB009800: AB_2251314, HPA024210: AB_10602011" "unprognostic (7.26e-3)" "unprognostic (1.00e-1)" "unprognostic (2.69e-1)" "unprognostic (3.23e-2)" "unprognostic (5.78e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (8.09e-4)" "unprognostic (2.83e-2)" "unprognostic (1.47e-1)" "unprognostic (5.22e-3)" "unprognostic (2.09e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-2)" "unprognostic (4.18e-1)" "unprognostic (1.63e-1)" 14.7 8.2 4.7 22.9 4.7 13.4 11.5 5.7 9.0 11.1 3.8 9.9 8.8 11.8 7.1 14.3 10.7 10.3 13.3 4.0 5.5 9.4 10.5 14.8 35.0 6.5 5.3 14.1 11.1 11.2 6.0 28.1 6.9 9.6 11.2 11.6 11.3 8.8 25.2 14.0 14.8 11.5 5.3 27.5 14.8 7.5 5.9 17.9 12.9 16.5 39.2 15.3 12.5 6.4 17.6 50.1 16.1 21.5 37.5 41.9 105.2 16.4 24.2 27.3 14.1 25.2 19.0 61.8 11.0 28.5 36.1 43.2 12.2 20.7 20.9 31.3 6.4 8.1 15.3 39.3 22.6 6.8 43.3 19.9 61.2 24.4 30.3 23.5 20.0 10.0 18.7 14.0 16.2 187.0 9.9 12.8 5.8 14.2 20.6 17.8 11.0 27.4 16.8 38.2 3.1 5.7 41.0 53.7 18.8 18.0 24.3 17.8 35.8 16.4 12.9 20.5 7.4 38.5 35.9 60.6 19.4 7.0 10.8 2.8 3.9 3.0 2.5 5.2 2.2 9.3 2.3 2.2 5.0 6.8 2.6 2.9 4.5 2.1 5.0 4.2 3.1 2.6 4.7 4.7 5.7 9.0 4.0 5.5 6.5 5.3 6.9 5.3 5.9 6.4 86.7 12.8 23.7 27.7 155.8 34.5 15.7 25.0 52.9 18.1 23.8 13.8 26.1 20.0 29.0 14.7 8.4 69.5 39.9 12.5 5.9 12.9 12.1 36.4 29.1 49.8 14.9 14.9 48.5 19.6 26.2 26.4 26.5 78.8 8.8 15.3 68.2 20.0 22.8 13.5 64.3 10.7 36.7 46.8 62.2 6.0 24.8 58.2 33.8 109.6 46.1 9.3 28.8 49.3 54.1 21.0 16.9 27.4 168.8 28.1 9.0 6.5 39.8 23.8 19.7 19.7 30.3 43.2 30.0 63.3 51.7 89.2 47.6 14.2 11.7 59.2 NCOA4 "ARA70, DKFZp762E1112, ELE1, PTC3, RFG" ENSG00000266412 "Nuclear receptor coactivator 4" Q13772 10 46005088-46030623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 476.2;Macrophages: 316.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 251.9;granulocytes: 839.6;monocytes: 363.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051260, HPA065208" Uncertain Approved "Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "Golgi apparatus, Cytosol" "HPA051260: AB_2681412, HPA065208: AB_2685432" "unprognostic (4.23e-2)" "unprognostic (1.50e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.34e-1)" "unprognostic (1.80e-1)" "unprognostic (9.34e-2)" "unprognostic (4.67e-2)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.04e-2)" "prognostic favorable (8.04e-6)" "unprognostic (1.35e-1)" "unprognostic (4.71e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" 117.1 67.8 45.6 91.5 52.5 189.5 96.9 56.1 50.9 85.1 50.7 110.3 249.7 70.2 74.6 110.3 62.6 87.8 156.8 40.6 55.8 159.7 372.9 108.3 102.6 52.4 53.5 65.5 64.6 97.9 25.2 131.3 53.6 132.2 115.7 33.7 79.2 78.7 163.5 71.1 155.9 98.3 52.6 148.1 90.3 43.6 51.6 124.4 87.0 193.6 150.3 104.6 46.8 60.0 142.7 58.5 68.0 70.4 176.9 159.4 170.3 128.3 204.8 122.1 119.6 91.0 102.3 161.2 149.2 211.2 69.1 141.8 72.6 142.3 137.1 114.4 74.1 108.4 74.3 263.5 124.0 279.9 229.7 156.1 139.2 104.2 175.7 131.6 185.5 79.5 119.7 93.5 171.9 64.0 136.1 104.3 41.4 110.2 34.8 79.5 99.3 96.7 148.9 119.4 68.2 46.1 128.9 146.2 131.5 133.5 105.7 135.3 171.6 75.8 89.9 81.3 87.5 69.3 79.1 156.9 94.6 231.2 41.2 692.1 363.6 611.8 78.9 223.6 86.2 57.6 73.3 74.9 251.9 53.8 78.2 66.4 839.6 119.0 275.3 77.4 92.8 559.4 45.6 52.5 56.1 50.9 40.6 55.8 52.4 53.5 53.6 52.6 51.6 60.0 44.5 51.3 95.2 13.4 44.6 49.5 39.3 126.2 50.7 14.3 49.6 38.5 161.3 45.8 96.2 44.1 29.2 104.7 58.2 108.8 80.3 45.3 105.4 45.1 37.7 52.9 26.9 476.2 17.4 51.8 107.2 45.3 42.3 56.9 195.2 28.2 55.3 166.7 181.4 20.2 20.5 45.4 59.0 254.5 74.2 72.4 37.3 316.1 51.6 16.9 158.4 38.2 44.3 18.6 22.9 47.8 63.9 47.4 37.6 62.0 162.5 128.8 59.7 13.0 13.1 36.7 46.7 24.5 16.5 71.9 56.7 158.2 41.3 60.7 71.3 52.0 NCOR1 "hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1" ENSG00000141027 "Nuclear receptor corepressor 1" O75376 17 16029157-16218185 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043246, HPA050288, HPA051168, CAB072830" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB072830: , HPA043246: AB_2678386, HPA050288: AB_2681073, HPA051168: AB_2681370" "unprognostic (1.83e-1)" "unprognostic (3.05e-1)" "unprognostic (9.17e-2)" "unprognostic (1.10e-1)" "unprognostic (7.38e-2)" "unprognostic (3.59e-2)" "unprognostic (2.55e-2)" "unprognostic (4.27e-2)" "unprognostic (4.87e-2)" "unprognostic (4.06e-2)" "unprognostic (7.07e-2)" "unprognostic (1.52e-2)" "prognostic favorable (7.92e-5)" "unprognostic (4.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" 22.1 18.3 37.8 28.1 39.7 42.8 29.0 60.8 84.7 27.3 41.0 44.0 47.1 30.7 20.3 30.6 25.1 26.4 23.4 39.3 34.7 33.6 46.2 26.9 29.9 32.7 35.7 33.5 34.2 42.3 17.1 28.3 31.0 27.6 40.6 41.4 22.4 31.4 42.0 31.6 38.2 29.7 28.2 29.3 42.7 32.4 35.4 51.9 34.8 39.9 34.7 28.8 18.3 43.4 68.0 110.6 77.7 65.1 62.4 47.1 38.6 48.9 54.8 52.4 47.1 59.8 30.3 70.9 33.6 85.9 39.3 50.4 96.4 59.2 77.3 95.6 71.1 70.7 96.3 71.1 60.8 45.3 80.7 48.5 60.6 81.2 94.4 45.2 73.9 98.0 63.0 28.8 52.3 44.3 79.3 29.1 38.6 118.6 29.9 78.1 78.5 33.5 54.9 76.0 26.5 43.8 80.7 34.7 37.7 197.5 33.5 50.3 65.5 53.7 32.6 39.9 68.3 19.7 25.0 40.4 51.0 52.4 47.0 408.4 104.8 240.4 126.9 86.0 106.7 188.4 144.0 141.0 76.3 191.4 139.8 139.0 205.2 139.9 112.3 130.3 144.7 98.8 37.8 39.7 60.8 84.7 39.3 34.7 32.7 35.7 31.0 28.2 35.4 43.4 90.9 80.1 113.2 116.2 130.0 67.8 106.2 91.3 86.0 150.3 76.8 60.8 91.5 82.9 86.9 53.3 158.4 102.1 121.7 198.1 35.2 95.5 69.7 75.7 109.5 88.4 87.9 132.1 127.0 96.5 101.7 77.1 149.4 103.7 87.3 88.9 67.5 126.4 76.1 129.5 122.2 118.8 81.4 81.9 76.7 43.6 101.5 96.7 37.4 107.7 172.8 83.1 197.8 123.1 151.4 111.7 148.3 121.5 88.5 95.6 194.4 46.7 63.8 167.1 92.1 106.0 106.2 98.7 90.2 78.0 68.2 87.6 142.1 89.5 153.0 122.9 NCOR2 "CTG26, SMRT, SMRTE, TNRC14, TRAC-1" ENSG00000196498 "Nuclear receptor corepressor 2" Q9Y618 12 124324415-124567589 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 6.0;non-classical monocyte: 2.5" "Group enriched" "Detected in many" 4 "granulocytes: 6.0;monocytes: 2.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001928 Approved Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA001928: AB_1079454" "unprognostic (9.51e-3)" "unprognostic (7.37e-3)" "unprognostic (4.66e-2)" "unprognostic (2.55e-3)" "unprognostic (2.14e-1)" "unprognostic (7.37e-2)" "unprognostic (3.19e-2)" "unprognostic (8.86e-2)" "unprognostic (2.21e-2)" "unprognostic (2.90e-3)" "unprognostic (6.42e-3)" "unprognostic (1.96e-1)" "unprognostic (9.86e-2)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (7.56e-2)" "unprognostic (8.90e-2)" 48.1 51.1 41.2 34.3 15.8 29.9 49.7 27.2 45.6 62.9 13.6 56.2 25.2 58.6 9.0 33.3 49.0 21.4 56.7 61.3 12.6 37.6 27.5 62.8 19.5 56.4 29.2 70.8 49.3 18.1 84.1 20.2 53.0 57.7 10.9 20.7 55.1 22.0 109.2 56.2 36.8 22.5 5.4 35.7 45.8 26.1 26.4 19.9 40.5 19.9 11.2 47.4 43.9 27.0 78.6 143.6 40.4 38.7 23.0 31.1 120.4 79.3 39.0 45.2 20.1 76.9 56.3 78.7 57.0 65.1 40.7 72.6 16.2 84.7 18.5 83.6 31.5 63.6 142.1 48.0 46.0 48.3 77.5 50.1 30.9 56.6 33.4 69.2 43.7 35.5 83.3 22.9 41.2 67.4 174.3 55.5 56.4 29.8 139.0 55.8 67.1 40.2 21.6 89.9 106.0 77.1 97.3 81.1 47.7 30.2 66.3 59.8 212.0 104.5 178.9 104.3 170.5 43.5 48.0 48.1 59.4 35.4 100.1 6.0 0.4 1.0 1.0 0.2 0.3 0.3 0.3 0.8 0.2 0.1 0.3 0.2 0.9 0.1 2.5 0.9 0.0 0.3 41.2 15.8 27.2 45.6 61.3 12.6 56.4 29.2 53.0 5.4 26.4 27.0 30.6 115.4 58.9 46.4 14.7 33.3 24.6 22.2 33.0 95.3 33.3 28.3 30.4 18.6 38.8 18.4 39.6 8.8 27.4 39.1 3.9 22.1 2.2 28.0 53.4 28.2 18.7 11.6 61.9 27.2 39.7 50.6 37.8 32.4 42.3 43.5 18.5 19.0 28.4 121.1 37.0 20.3 4.1 50.0 48.7 7.1 62.1 44.8 16.0 51.5 27.0 28.0 20.6 70.9 65.9 38.0 22.2 65.1 22.6 23.7 25.4 8.0 16.8 65.9 6.6 63.0 35.5 1.8 11.6 17.7 24.4 12.6 25.1 69.4 21.9 23.1 NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 613.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 571.9;Distal enterocytes: 405.4;Horizontal cells: 588.9;Suprabasal keratinocytes: 667.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 606.9;hTERT-HME1: 1226.9;U-87 MG: 772.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" 161.2 72.9 299.1 55.9 523.6 130.0 107.6 413.5 300.2 169.4 132.8 130.0 242.2 92.9 34.3 343.1 106.4 87.8 99.8 254.5 316.6 192.4 49.6 116.6 38.7 523.2 500.0 126.1 52.8 69.1 82.2 110.8 476.8 354.3 77.8 86.0 130.8 60.0 28.2 262.6 258.1 61.9 333.7 39.4 154.0 28.1 423.1 55.1 80.5 44.6 88.1 105.5 273.8 613.9 191.6 24.0 1.7 0.8 116.3 86.8 26.0 13.7 103.0 9.8 52.5 12.5 27.6 1.5 133.0 58.0 21.9 62.4 1.7 316.8 18.0 13.3 226.8 1.9 55.6 14.7 46.3 7.0 4.6 79.2 606.9 51.2 1226.9 124.2 45.2 27.9 2.0 138.3 17.2 11.0 19.1 20.8 3.0 69.8 155.8 1.7 19.4 86.2 29.7 28.0 13.8 13.0 31.0 312.1 73.3 48.6 1.3 20.0 58.5 84.4 43.6 40.7 10.4 96.3 280.3 0.8 772.5 69.5 161.5 10.9 4.3 0.0 5.8 3.4 9.1 1.6 5.3 6.9 6.0 1.4 3.9 3.1 4.0 1.5 4.2 13.0 8.1 3.7 299.1 523.6 413.5 300.2 254.5 316.6 523.2 500.0 476.8 333.7 423.1 613.9 123.0 144.2 47.4 14.4 23.6 571.9 141.3 207.3 42.1 68.8 28.6 31.2 20.6 80.1 102.9 187.6 2.1 12.8 68.1 405.4 33.2 33.2 5.3 57.4 59.0 217.7 22.1 17.4 7.7 13.7 138.2 90.5 151.4 167.7 22.2 41.0 112.8 64.0 16.5 588.9 5.7 140.9 83.4 31.1 109.5 5.9 49.0 42.7 101.4 28.1 25.7 81.2 14.4 20.6 136.2 62.9 155.9 44.0 23.5 264.3 402.5 87.5 38.7 40.3 46.0 65.2 44.3 1.2 7.1 113.0 667.4 43.4 45.7 32.6 124.7 280.8 NEB "NEB177D, NEM2" ENSG00000183091 Nebulin P20929 2 151485336-151734487 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 69 "skeletal muscle: 9300.2;tongue: 2495.6" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 662.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 8.8;RH-30: 34.3;U-266/70: 12.8" "Group enriched" "Detected in some" 6 "cerebellum: 6.5;olfactory bulb: 4.0" "Region enriched" "Detected in some" 6 "cerebellum: 11.8" HPA016601 Enhanced NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "HPA016601: AB_1854361" "unprognostic (2.40e-2)" "unprognostic (6.71e-2)" "unprognostic (2.13e-2)" "unprognostic (2.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-3)" "unprognostic (2.54e-2)" "unprognostic (1.45e-1)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-13)" "unprognostic (6.80e-2)" "unprognostic (2.22e-2)" "unprognostic (4.07e-3)" "unprognostic (4.06e-2)" 2.3 6.4 2.2 0.7 5.0 1.3 2.9 4.0 2.6 0.5 1.4 1.3 1.1 0.6 1.6 16.2 0.5 12.7 40.7 2.2 5.4 3.3 4.9 2.3 1.3 2.9 2.9 0.9 2.0 0.1 2.6 0.8 2.4 22.1 0.1 3.5 85.9 0.2 9300.2 9.3 1.8 0.2 2.0 3.0 1.1 1.7 2.9 1.1 13.0 2495.6 0.8 0.4 1.2 2.9 0.5 0.5 0.8 0.7 0.1 0.1 2.3 0.4 0.0 0.0 0.0 6.1 0.7 1.7 1.2 0.1 0.2 1.2 0.1 0.0 0.0 0.8 0.9 0.6 1.1 2.0 0.0 1.1 1.5 5.0 0.3 0.1 0.0 0.3 0.8 0.5 1.2 8.8 0.5 0.7 0.6 1.1 1.4 3.0 1.0 1.6 34.3 0.2 0.1 1.2 2.0 0.3 0.3 0.4 0.2 1.3 0.9 1.1 0.8 0.9 1.2 0.1 1.2 12.8 2.0 0.4 0.2 0.8 1.5 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.2 5.0 4.0 2.6 2.2 5.4 2.9 2.9 2.4 2.0 2.9 2.9 0.3 0.0 1.1 14.0 2.0 0.8 1.2 0.2 2.8 2.4 0.5 0.4 82.6 18.6 0.7 0.0 0.0 0.5 1.2 0.0 0.0 0.5 7.6 1.4 1.5 2.1 1.8 0.0 13.1 0.0 0.4 10.6 2.0 2.5 1.3 2.2 0.7 2.4 0.7 3.3 9.2 0.0 4.1 1.3 0.7 7.6 0.6 2.7 0.0 7.5 0.2 0.4 0.0 6.0 5.2 0.1 0.0 0.0 2.0 1.1 0.3 0.4 0.1 1.7 0.0 662.8 1.9 1.4 1.6 0.2 1.3 0.8 1.1 1.5 0.0 0.2 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Excitatory neurons: 280.9" "Cancer enhanced" "Detected in all" "prostate cancer: 29.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 146.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 11.2 16.8 20.9 6.7 34.4 27.0 25.8 25.1 31.3 7.6 0.7 38.8 18.7 5.3 10.0 12.0 9.1 9.5 26.9 32.3 16.2 53.4 36.5 47.9 4.1 10.9 18.4 6.4 60.5 13.6 28.4 12.0 10.4 64.2 42.8 20.5 27.5 20.4 34.0 11.2 33.8 6.2 8.6 7.9 51.5 7.8 16.7 4.5 17.4 13.1 7.9 19.4 5.9 16.3 70.7 24.5 14.6 20.9 5.1 2.1 49.8 19.2 88.2 48.6 74.6 28.6 37.1 15.1 57.7 7.4 51.3 50.3 19.5 86.1 100.8 34.9 15.5 10.6 14.3 111.3 2.4 0.5 6.0 13.0 54.6 66.4 78.8 39.1 4.0 13.2 18.7 6.3 20.0 16.2 1.0 1.0 12.2 26.7 33.3 14.3 20.1 17.6 47.0 88.7 17.5 5.0 16.1 5.1 146.1 28.3 29.4 5.6 28.8 131.5 38.5 7.5 83.4 8.3 15.3 9.5 27.6 10.8 10.8 0.7 0.3 1.2 0.2 0.3 0.5 0.8 0.6 0.1 0.1 0.3 0.3 0.2 0.2 0.3 0.1 0.1 5.1 0.3 20.9 34.4 25.1 31.3 32.3 16.2 10.9 18.4 10.4 8.6 16.7 16.3 6.0 253.2 144.8 110.4 5.1 112.8 161.2 34.0 86.6 18.1 99.5 65.9 47.8 64.3 112.8 62.5 173.0 13.0 3.6 144.5 49.0 35.7 22.6 64.0 7.3 14.7 45.2 57.9 280.9 49.2 4.7 9.5 114.7 75.0 3.8 4.7 17.5 41.3 7.3 62.2 173.3 201.5 101.7 8.4 8.2 6.6 3.4 13.3 14.2 88.1 7.3 45.2 2.1 11.1 105.0 49.9 145.3 17.7 12.7 126.9 127.3 91.6 72.7 10.0 0.0 34.3 6.0 1.1 12.5 62.3 53.0 80.0 6.6 8.2 72.9 155.5 NEDD8 Nedd-8 ENSG00000129559 "NEDD8 ubiquitin like modifier" Q15843 14 24216857-24232367 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004082, HPA027583, HPA060254" Uncertain Enhanced Nucleoplasm,Cytosol NA NA 990000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Cytosol "CAB004082: AB_10695300, HPA027583: AB_2732439, HPA060254: AB_2732644" "unprognostic (1.26e-2)" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.34e-3)" "unprognostic (1.83e-3)" "unprognostic (9.19e-2)" "unprognostic (4.66e-1)" "unprognostic (1.35e-2)" "unprognostic (2.66e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-3)" "unprognostic (2.76e-2)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (5.25e-3)" 169.0 224.3 156.9 71.5 162.3 91.0 156.7 158.6 219.1 152.4 152.5 172.9 55.9 147.6 132.6 202.1 131.3 51.0 299.8 163.1 168.6 195.8 175.7 147.7 81.2 163.7 158.7 138.1 110.9 289.1 143.9 84.3 162.4 133.7 88.7 74.6 139.3 85.5 294.3 182.2 128.8 97.7 157.5 164.6 146.8 77.9 162.1 125.7 132.8 197.1 113.1 152.0 157.5 162.0 166.9 292.7 223.8 159.9 255.2 223.2 165.6 218.7 237.4 259.5 237.5 204.6 196.1 142.1 126.9 317.1 212.3 169.2 230.8 349.5 365.6 201.9 139.7 150.2 272.9 710.7 220.8 251.8 151.6 237.0 231.8 217.2 172.0 239.1 317.3 162.3 139.3 161.5 409.4 380.3 203.4 241.1 166.1 303.7 335.8 141.3 176.9 146.1 302.7 322.1 96.7 221.7 188.3 192.6 168.4 229.5 117.6 199.2 230.3 145.4 144.9 184.9 198.5 187.9 322.7 210.6 102.6 146.2 139.6 461.6 277.3 459.9 214.7 302.8 235.5 311.9 246.0 241.0 276.3 273.4 229.8 233.1 299.8 233.7 310.5 369.7 327.3 526.6 156.9 162.3 158.6 219.1 163.1 168.6 163.7 158.7 162.4 157.5 162.1 162.0 276.4 144.2 156.8 0.0 182.1 277.9 227.5 644.7 166.8 101.0 263.4 301.5 464.7 215.9 301.5 310.8 47.9 525.7 237.0 267.8 594.8 344.9 72.6 201.8 189.4 259.5 212.4 220.7 0.0 406.9 625.0 246.0 108.1 195.4 218.6 228.7 222.0 431.5 576.3 106.0 0.0 286.4 362.2 288.7 345.5 77.3 272.1 255.4 268.6 0.0 394.0 275.0 346.1 0.0 0.0 449.8 311.5 275.7 161.3 254.4 340.2 845.8 279.7 95.9 210.4 178.7 318.4 150.0 196.9 252.1 386.6 419.5 216.0 289.8 291.8 275.5 NEO1 "HsT17534, IGDCC2, NGN, NTN1R2" ENSG00000067141 "Neogenin 1" Q92859 15 73051710-73305205 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 231.8;Excitatory neurons: 124.5;Oligodendrocyte precursor cells: 120.1;Oligodendrocytes: 439.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009320, HPA027804, HPA027805, HPA027806" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 390000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB009320: AB_2150998, HPA027804: AB_10600771, HPA027805: AB_10601755, HPA027806: AB_10601006" "unprognostic (1.90e-1)" "unprognostic (2.38e-2)" "unprognostic (7.60e-3)" "unprognostic (3.76e-2)" "unprognostic (5.44e-1)" "unprognostic (3.83e-2)" "unprognostic (8.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.22e-1)" "unprognostic (3.30e-2)" "unprognostic (5.51e-2)" "unprognostic (8.05e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.51e-1)" "unprognostic (1.41e-1)" "unprognostic (1.33e-2)" "unprognostic (3.75e-1)" 9.6 7.4 28.9 8.9 43.8 1.5 16.7 38.1 31.4 18.2 10.7 46.0 27.3 19.6 9.9 11.5 21.9 19.6 7.8 29.4 29.2 23.4 8.7 15.9 3.9 34.6 38.0 24.8 17.2 41.8 6.7 1.7 35.6 33.0 55.1 19.5 18.3 36.0 30.9 37.5 26.5 23.3 28.7 5.3 22.9 13.5 36.6 7.2 18.2 24.8 6.2 10.5 9.6 60.0 8.9 42.9 50.1 33.2 29.6 8.6 12.5 3.3 4.1 8.2 1.7 6.4 42.8 2.5 4.9 9.4 30.8 1.9 35.3 19.5 3.5 15.8 26.0 29.0 0.5 6.0 8.6 0.8 0.9 21.3 35.4 1.6 16.2 9.5 0.0 22.3 0.2 53.9 2.0 26.8 10.5 0.7 47.9 6.7 3.6 23.9 26.8 5.8 15.8 23.7 22.7 32.1 40.2 17.6 20.7 39.9 18.6 5.3 0.1 38.0 19.9 12.5 9.3 22.8 45.2 6.2 8.2 8.3 10.9 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.2 0.3 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.1 28.9 43.8 38.1 31.4 29.4 29.2 34.6 38.0 35.6 28.7 36.6 60.0 3.1 9.6 10.4 231.8 2.3 14.1 8.2 20.7 13.6 15.7 14.2 18.2 6.9 21.5 11.4 22.0 14.6 0.5 4.8 55.6 1.9 11.6 3.3 14.4 13.4 3.4 60.1 3.0 124.5 6.4 0.8 14.6 20.9 24.6 0.0 11.8 5.7 8.9 0.9 10.1 72.8 51.2 10.2 1.2 2.7 7.1 31.7 1.2 10.6 62.8 0.1 12.5 2.1 120.1 439.4 9.9 40.0 62.8 2.6 11.5 39.6 15.5 12.7 21.9 6.6 22.2 10.2 11.8 20.3 14.7 25.4 0.3 6.0 3.1 60.5 7.2 NF1 ENSG00000196712 "Neurofibromin 1" P21359 17 31094927-31382116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 254.0;Excitatory neurons: 325.3;Inhibitory neurons: 412.5;Oligodendrocyte precursor cells: 428.2;Oligodendrocytes: 317.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045502 Uncertain Approved Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA045502: AB_2679352" "unprognostic (6.69e-2)" "unprognostic (8.73e-2)" "unprognostic (8.26e-2)" "unprognostic (1.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.30e-2)" "unprognostic (3.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (3.70e-1)" 7.4 8.4 8.9 7.1 10.7 3.4 11.5 13.2 12.2 10.0 1.6 8.5 6.8 10.2 10.0 6.1 9.0 8.0 11.3 9.7 11.7 12.0 9.4 7.3 7.7 11.7 9.2 13.5 10.4 15.9 7.8 12.4 9.1 9.5 8.8 20.9 9.1 9.5 8.1 7.4 7.5 8.7 8.2 7.1 8.2 10.0 11.8 13.5 19.5 10.6 7.8 10.4 6.8 14.4 15.8 20.3 24.2 13.1 20.1 25.8 12.2 13.4 24.1 19.5 21.8 18.4 10.5 15.2 3.8 25.1 22.9 26.8 22.2 18.7 32.6 7.5 14.1 13.4 18.8 9.5 14.2 24.4 10.6 20.7 11.8 20.8 25.1 21.8 9.5 15.7 19.8 14.8 18.8 12.4 20.4 8.8 7.1 9.7 6.8 15.8 36.8 12.3 14.7 22.5 10.0 14.9 25.4 8.3 13.8 16.8 25.0 15.3 14.1 15.3 21.5 18.8 5.1 13.2 6.9 16.3 12.6 10.0 16.2 4.4 0.3 0.6 1.5 0.1 1.0 1.4 2.8 2.5 0.4 1.2 2.0 2.0 0.7 0.7 0.3 0.4 5.9 0.6 8.9 10.7 13.2 12.2 9.7 11.7 11.7 9.2 9.1 8.2 11.8 14.4 30.9 32.1 31.1 254.0 18.3 38.6 48.1 38.9 31.9 62.7 33.7 24.9 43.9 41.5 29.8 40.5 137.6 57.5 23.8 37.8 23.5 27.1 210.4 27.4 39.4 35.8 19.8 9.7 325.3 22.5 26.6 39.1 39.3 45.8 10.8 44.0 33.2 35.7 22.5 70.7 412.5 24.3 38.7 27.6 34.1 94.6 37.3 28.2 21.4 215.5 20.9 47.5 21.6 428.2 317.4 33.3 43.0 50.4 30.8 54.2 32.1 28.6 36.9 62.8 46.0 51.9 43.3 30.5 28.7 19.8 34.0 49.3 19.8 36.1 27.4 64.5 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.1;Late spermatids: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 8.8 13.6 19.7 8.4 17.2 8.0 7.6 13.6 28.7 8.9 10.7 10.8 6.2 11.1 6.2 13.4 8.6 5.3 21.4 27.3 13.9 17.2 10.5 9.3 6.4 14.4 18.1 8.5 12.7 27.4 9.5 4.6 14.3 9.9 5.4 7.3 8.5 6.7 22.8 10.2 8.8 8.0 14.3 9.9 10.0 20.9 17.6 9.3 11.1 19.1 7.1 9.3 7.7 16.6 75.8 36.7 12.2 74.3 21.5 22.0 7.7 57.3 37.9 74.1 53.7 32.7 18.4 21.1 50.4 69.9 48.9 27.1 25.1 37.8 52.0 31.9 12.5 26.8 24.4 26.4 22.4 35.1 28.6 20.1 16.4 53.3 51.0 21.8 47.7 13.7 12.0 18.7 64.5 35.1 21.4 16.6 8.3 16.9 20.4 24.2 56.8 18.8 68.5 37.3 17.0 11.6 36.0 24.5 14.0 9.4 14.9 15.4 92.7 101.1 109.6 44.8 112.5 30.0 26.7 25.5 27.0 14.5 68.5 10.0 10.0 4.2 15.5 14.7 13.1 8.3 11.5 10.4 15.1 8.6 9.7 9.2 2.3 13.2 21.0 10.2 10.7 12.2 19.7 17.2 13.6 28.7 27.3 13.9 14.4 18.1 14.3 14.3 17.6 16.6 8.1 6.4 20.1 14.7 9.4 14.1 11.6 9.8 8.6 16.3 14.5 9.0 23.1 18.6 10.0 14.7 10.4 11.7 12.7 9.0 21.5 40.0 77.1 14.5 17.7 13.2 13.1 13.9 27.5 24.9 6.7 12.5 7.7 15.2 22.9 12.2 11.7 14.4 13.5 30.3 27.1 7.9 6.1 14.7 7.5 121.4 7.2 10.2 8.8 18.7 8.6 19.1 14.4 17.6 16.7 40.1 14.5 12.4 14.7 13.6 10.5 30.1 8.6 9.6 6.6 13.7 15.6 29.5 8.1 15.5 14.3 3.8 12.9 17.4 11.2 9.5 NFATC2 "NF-ATP, NFAT1, NFATp" ENSG00000101096 "Nuclear factor of activated T cells 2" Q13469 20 51386957-51562831 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 26.0" "Cell type enhanced" "Detected in many" "Microglial cells: 96.5;NK-cells: 105.0;Skeletal myocytes: 152.0;T-cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 24.5;HMC-1: 26.8;SK-MEL-30: 20.4;WM-115: 41.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA008789, CAB018567, HPA024369" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Cytosol" "CAB018567: AB_628012, HPA008789: AB_1079474, HPA024369: AB_1854413" "unprognostic (2.69e-3)" "unprognostic (2.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.58e-2)" "unprognostic (1.15e-1)" "unprognostic (1.26e-2)" "unprognostic (3.94e-2)" "unprognostic (4.05e-2)" "unprognostic (9.26e-2)" "unprognostic (3.74e-3)" "unprognostic (2.17e-2)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (9.25e-2)" "unprognostic (1.02e-1)" "unprognostic (1.05e-2)" "unprognostic (6.59e-2)" 7.6 2.1 2.8 7.4 5.4 4.8 4.6 2.8 3.2 3.8 26.0 4.2 7.9 3.9 3.4 3.6 4.2 16.5 3.1 2.1 3.6 1.7 6.1 4.8 16.1 6.5 7.4 2.1 8.0 3.1 1.4 7.5 4.6 2.4 3.7 0.1 4.8 2.5 3.3 3.8 6.1 2.8 3.5 12.6 10.7 1.6 6.7 5.0 3.5 0.9 13.6 6.5 2.0 3.7 2.7 2.9 0.0 3.6 0.0 0.0 7.5 0.4 1.9 1.2 0.6 14.0 2.5 18.7 2.1 0.9 2.5 0.0 0.9 0.0 1.1 24.5 0.4 8.0 2.1 3.6 0.0 2.2 26.8 0.0 0.0 1.0 0.1 0.2 8.4 6.5 8.0 12.1 0.0 3.1 3.3 13.3 0.3 1.7 6.6 1.4 0.0 8.3 0.4 0.0 0.3 0.0 8.6 2.1 20.4 1.7 3.3 5.3 0.9 1.7 3.0 4.1 0.2 10.2 7.2 18.6 1.7 8.7 41.1 0.4 0.0 3.1 5.3 0.5 2.2 1.3 2.9 4.3 1.2 1.1 1.6 3.0 0.1 5.7 0.2 0.5 1.7 1.3 2.8 5.4 2.8 3.2 2.1 3.6 6.5 7.4 4.6 3.5 6.7 3.7 16.0 6.4 5.4 14.0 38.1 14.4 16.1 0.9 0.6 0.0 8.7 4.3 3.6 4.3 5.6 0.0 0.0 3.3 42.7 1.9 1.9 3.7 1.6 13.1 12.1 28.0 7.8 18.1 1.7 5.6 0.8 37.2 23.4 12.2 15.2 0.2 30.7 7.5 37.1 0.0 1.0 6.2 0.0 32.5 56.6 0.8 2.1 19.0 62.2 96.5 5.0 0.0 105.0 2.5 5.0 11.4 1.8 0.4 55.8 5.3 1.4 0.3 9.3 0.0 0.0 152.0 15.2 0.4 0.7 3.8 12.9 1.0 65.5 0.0 7.0 6.6 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favorable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 87.0 73.6 64.8 65.4 83.9 58.9 78.3 74.9 86.7 83.2 78.7 83.4 100.1 92.6 97.2 257.0 88.5 97.7 77.6 66.5 71.6 143.5 176.6 88.5 50.4 82.0 77.5 137.3 47.3 60.4 58.4 80.4 84.5 72.7 85.8 68.2 79.7 90.5 64.4 162.3 82.9 91.8 70.4 69.0 176.9 65.2 75.7 68.2 130.4 65.9 93.8 160.7 108.7 91.8 53.1 57.3 52.2 56.4 181.4 190.2 61.7 91.8 124.9 81.4 90.5 75.9 97.9 52.8 93.8 102.8 148.4 96.9 65.1 136.7 111.5 40.8 41.1 65.9 95.9 156.3 231.2 39.3 60.6 134.0 314.5 115.5 169.3 184.4 80.9 39.7 72.7 91.4 111.8 49.8 42.3 101.9 58.8 277.2 58.9 34.0 46.5 54.6 120.9 182.1 69.0 45.0 202.9 64.8 216.6 147.8 49.1 105.0 119.9 80.4 54.5 89.5 54.7 70.1 44.7 43.1 81.6 43.3 159.4 130.6 89.3 55.4 55.2 84.3 62.9 61.8 64.0 57.0 100.4 51.9 101.2 66.8 103.2 68.1 83.0 38.8 66.6 66.0 64.8 83.9 74.9 86.7 66.5 71.6 82.0 77.5 84.5 70.4 75.7 91.8 193.3 157.0 93.5 66.3 143.3 295.8 241.8 448.4 306.7 61.3 90.0 113.7 67.9 117.2 247.0 154.5 16.7 113.2 249.1 120.7 393.2 154.5 81.4 238.1 126.9 139.6 75.6 58.0 25.3 170.8 34.5 206.6 170.7 279.9 212.7 141.5 120.0 93.2 88.1 57.2 26.6 73.5 321.4 111.6 569.9 39.0 287.7 266.0 96.0 88.1 170.6 191.4 55.6 63.8 113.0 128.3 91.8 214.0 118.8 150.5 94.9 85.0 205.9 48.4 39.5 211.8 152.4 66.1 32.1 617.9 315.4 186.2 150.6 153.5 119.6 225.2 NFIB "NFI-RED, NFIB2, NFIB3" ENSG00000147862 "Nuclear factor I B" O00712 9 14081843-14398983 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 542.6;Oligodendrocyte precursor cells: 565.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 160.3;HBEC3-KT: 65.9;HEL: 61.3;HUVEC TERT2: 64.8;TIME: 64.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003956 Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli fibrillar center" "HPA003956: AB_1854424" "unprognostic (1.93e-1)" "unprognostic (3.18e-2)" "unprognostic (4.00e-1)" "unprognostic (2.16e-3)" "unprognostic (1.12e-1)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (4.72e-3)" "unprognostic (7.46e-2)" "unprognostic (9.35e-2)" "unprognostic (3.68e-1)" "unprognostic (1.12e-1)" "prognostic favorable (3.53e-4)" "unprognostic (4.69e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-2)" "unprognostic (1.62e-1)" 28.3 8.8 22.6 7.2 19.3 0.2 36.8 35.7 25.9 12.5 5.8 16.8 10.1 13.0 15.1 9.8 17.5 15.9 25.7 23.7 9.1 16.7 20.3 15.9 7.8 13.2 14.7 14.1 15.6 5.0 4.9 13.0 13.1 20.3 8.7 10.0 39.7 16.9 21.5 22.0 13.0 15.7 17.6 9.7 14.2 2.4 10.9 7.1 17.4 18.9 5.6 17.7 13.3 15.2 19.7 14.7 8.6 160.3 39.8 22.9 0.5 0.5 0.0 3.7 13.7 0.2 7.9 0.5 12.1 1.2 12.0 4.3 7.8 65.9 7.3 2.8 7.4 61.3 31.6 1.8 13.2 1.8 0.3 20.3 9.0 14.2 49.5 15.4 64.8 0.0 1.8 0.5 5.3 9.0 0.1 0.4 3.0 8.8 15.9 0.2 7.5 0.2 11.9 7.4 13.5 49.9 13.5 16.9 5.7 0.5 34.0 0.1 64.6 12.1 18.1 9.7 12.2 1.6 1.4 4.8 11.2 0.3 15.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 22.6 19.3 35.7 25.9 23.7 9.1 13.2 14.7 13.1 17.6 10.9 15.2 328.7 51.3 31.4 542.6 4.6 268.9 165.7 63.0 115.5 60.8 238.6 317.4 195.6 214.4 59.1 46.0 0.0 5.1 2.1 42.1 39.2 70.7 3.6 147.8 39.0 230.9 22.8 2.7 278.5 125.2 1.2 190.9 62.2 135.9 3.8 5.7 228.5 104.0 2.2 0.0 352.9 35.4 28.5 8.4 48.9 5.0 133.9 7.3 94.3 157.4 1.7 238.0 0.0 565.5 206.0 68.1 48.7 48.5 4.1 166.2 101.9 190.7 55.6 11.5 85.5 270.5 160.8 0.9 9.7 78.6 169.2 1.6 7.1 6.5 74.2 64.3 NFKB1 "KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50" ENSG00000109320 "Nuclear factor kappa B subunit 1" P19838 4 102501331-102617302 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 610.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004031, HPA027305" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB004031: AB_330564, HPA027305: AB_1854429" "unprognostic (1.06e-1)" "unprognostic (1.61e-2)" "unprognostic (4.37e-2)" "unprognostic (2.38e-2)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (2.04e-2)" "unprognostic (8.98e-2)" "unprognostic (1.96e-1)" "unprognostic (9.03e-3)" "unprognostic (2.28e-1)" "unprognostic (2.71e-1)" "prognostic favorable (1.76e-4)" "unprognostic (1.84e-2)" "unprognostic (6.75e-3)" "unprognostic (1.74e-1)" "unprognostic (6.92e-3)" 26.7 16.2 3.9 30.3 7.0 34.6 19.8 6.5 5.7 22.0 5.5 20.4 15.2 18.9 2.7 23.0 19.1 20.8 15.8 4.2 5.8 17.4 16.4 25.0 33.1 7.6 6.1 18.8 16.0 11.7 7.7 21.2 7.8 17.3 19.6 4.9 18.9 17.8 20.9 23.7 20.3 17.0 5.6 23.0 17.5 7.6 6.4 37.0 16.3 10.7 35.1 48.5 19.9 10.1 36.8 19.2 11.2 13.6 27.0 28.5 10.9 20.0 64.2 27.7 27.1 21.5 40.8 58.0 17.6 32.6 39.4 29.5 22.0 34.5 35.2 53.6 10.8 22.7 14.5 15.0 20.0 44.3 44.3 19.7 20.2 22.0 34.4 15.0 34.5 18.1 25.8 34.1 17.6 17.7 4.1 9.1 5.0 24.3 15.4 33.4 25.9 24.0 15.3 38.8 7.1 11.8 38.3 37.2 16.3 8.3 8.6 24.2 40.5 32.5 16.6 14.5 26.4 17.0 13.3 52.0 20.8 19.4 44.1 0.0 2.1 2.6 0.9 3.0 1.9 1.9 3.0 1.6 4.8 1.7 4.5 3.2 1.9 3.7 3.1 1.5 0.8 1.6 3.9 7.0 6.5 5.7 4.2 5.8 7.6 6.1 7.8 5.6 6.4 10.1 32.5 41.7 49.4 42.1 90.0 165.4 91.5 57.1 31.3 6.6 41.5 32.6 19.1 24.3 40.8 20.2 6.2 14.4 119.6 41.1 3.9 28.5 7.6 82.5 62.0 47.6 33.6 13.0 78.4 37.3 16.9 63.1 29.6 207.0 111.1 19.8 23.9 23.9 24.8 20.2 77.2 43.2 18.3 56.2 610.3 2.4 23.9 178.3 55.2 59.0 207.9 9.5 23.7 66.9 127.4 46.3 27.1 34.6 56.3 78.5 21.1 24.4 31.5 6.7 0.0 73.7 41.2 2.5 8.1 35.3 150.3 14.2 88.2 16.7 35.4 90.2 NFKB2 "LYT-10, NF-kB2, p105, p49/p100, p52" ENSG00000077150 "Nuclear factor kappa B subunit 2" Q00653 10 102394110-102402524 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 122.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 168.0;Karpas-707: 157.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008422, CAB022098, HPA023900" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoplasm "CAB022098: , HPA008422: AB_1854434, HPA023900: AB_1854435" "unprognostic (1.10e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (1.53e-2)" "unprognostic (8.08e-3)" "unprognostic (2.15e-1)" "unprognostic (2.38e-3)" "unprognostic (3.98e-2)" "prognostic favorable (8.45e-5)" "unprognostic (4.04e-1)" "unprognostic (8.34e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.69e-12)" "unprognostic (2.37e-3)" "unprognostic (1.63e-1)" "unprognostic (4.90e-2)" "unprognostic (1.56e-1)" 26.5 21.0 7.6 44.4 7.4 69.3 19.6 7.1 9.2 22.9 8.5 39.1 15.5 21.6 2.3 17.7 20.4 18.5 20.6 7.2 7.2 34.6 28.2 41.0 40.7 8.5 7.5 21.4 24.1 6.1 10.8 14.7 8.0 29.0 6.8 1.1 21.3 9.1 18.4 20.0 26.5 12.2 7.5 50.6 22.7 10.0 8.4 16.9 20.1 7.6 25.7 37.0 19.1 8.0 67.9 48.6 7.7 31.7 11.1 16.6 19.3 18.5 61.0 19.6 25.9 28.6 55.2 32.9 43.5 11.9 48.8 40.9 20.5 28.2 6.8 168.0 11.2 7.0 11.7 15.9 30.1 5.1 45.5 22.0 14.6 34.1 32.3 26.5 7.8 16.1 7.6 157.8 7.4 26.4 7.1 22.7 10.3 15.7 16.6 16.8 24.5 27.0 34.3 22.1 1.7 8.2 16.2 36.7 26.3 7.2 29.3 16.4 21.2 19.0 28.9 25.4 47.0 113.1 105.0 32.6 31.1 14.8 10.9 0.0 1.3 0.0 0.7 0.9 0.7 2.6 0.8 0.7 0.7 2.1 0.8 0.8 5.6 0.8 2.1 0.6 1.1 0.5 7.6 7.4 7.1 9.2 7.2 7.2 8.5 7.5 8.0 7.5 8.4 8.0 20.8 9.6 8.8 3.3 88.3 43.5 59.3 41.2 34.7 2.2 17.1 14.5 3.1 25.8 29.9 18.4 16.7 6.3 39.0 33.3 5.9 33.2 1.1 33.7 14.4 26.1 16.3 0.4 0.1 21.0 15.8 26.0 80.0 52.0 71.8 5.5 11.7 3.7 20.9 0.0 0.1 30.4 22.4 19.4 122.9 1.7 7.5 52.5 30.2 1.9 75.1 3.9 12.3 1.5 0.7 44.9 37.4 4.9 49.1 49.3 33.2 8.6 19.9 5.3 0.0 36.4 43.6 4.7 11.1 17.5 44.6 23.1 54.6 8.8 17.9 45.6 NFKBIA "IkappaBalpha, IKBA, MAD-3, NFKBI" ENSG00000100906 "NFKB inhibitor alpha" P25963 14 35401513-35404749 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1114.7" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 4056.6;Langerhans cells: 4828.7;Suprabasal keratinocytes: 3420.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 391.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003815, HPA029207" Approved Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "CAB003815: AB_344886, HPA029207: AB_10603122" "prognostic favorable (1.33e-5)" "unprognostic (3.39e-1)" "unprognostic (7.29e-2)" "unprognostic (7.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.51e-1)" "unprognostic (2.46e-1)" "unprognostic (2.39e-1)" "unprognostic (2.46e-1)" "unprognostic (2.46e-1)" "unprognostic (7.19e-2)" "unprognostic (2.32e-2)" "unprognostic (3.69e-1)" "unprognostic (4.44e-2)" "unprognostic (9.74e-2)" "unprognostic (3.80e-2)" 281.0 171.3 75.6 150.7 78.0 1114.7 171.4 75.4 92.5 123.8 78.3 121.0 61.2 95.5 29.6 151.8 141.2 130.4 145.5 71.4 75.9 104.5 208.1 366.0 122.6 90.1 76.2 255.7 101.9 68.8 92.4 92.7 81.6 112.6 80.9 18.7 118.3 110.0 139.7 260.5 148.5 92.7 77.0 226.2 130.7 31.7 84.9 123.2 111.9 138.3 181.4 366.2 166.8 79.8 62.5 54.1 20.1 18.2 114.7 75.9 71.1 25.2 240.7 53.3 47.3 16.9 36.5 37.5 66.1 40.2 125.2 79.5 38.3 104.9 76.1 229.2 14.9 18.6 39.9 101.4 68.6 29.9 15.0 83.1 103.5 36.4 92.2 35.5 48.6 18.4 15.9 58.4 38.6 73.0 39.2 71.0 18.6 60.0 33.1 87.8 23.1 31.6 92.8 391.7 17.9 31.2 67.2 115.9 29.7 41.0 66.1 62.2 91.7 72.8 26.5 21.3 41.0 70.9 77.7 64.5 60.8 22.0 15.3 322.0 444.9 301.4 175.3 267.2 264.0 258.4 207.1 182.5 428.9 329.7 178.1 153.0 942.9 285.9 183.7 233.0 154.9 506.4 75.6 78.0 75.4 92.5 71.4 75.9 90.1 76.2 81.6 77.0 84.9 79.8 802.9 535.2 914.0 14.4 505.6 4056.6 1862.8 2061.4 1729.6 27.0 430.7 414.0 188.6 367.4 719.2 62.5 12.5 196.4 762.2 447.8 195.6 875.0 4.3 703.8 935.6 1079.8 203.5 87.8 7.1 394.8 174.9 1145.1 333.8 1440.1 906.1 68.2 313.4 147.2 791.2 48.8 5.1 453.0 634.7 491.4 4828.7 14.7 153.1 1609.0 1085.1 39.4 428.1 95.2 97.9 6.6 8.6 383.5 511.5 116.2 1039.4 1412.0 1051.6 115.9 298.2 37.4 203.8 956.9 847.2 3.3 26.4 1544.6 3420.6 660.0 838.4 91.8 346.0 1004.6 NFKBIE IKBE ENSG00000146232 "NFKB inhibitor epsilon" O00221 6 44258166-44265788 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002692, HPA005941, CAB010272" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB010272: AB_2235977, HPA002692: AB_1079479, HPA005941: AB_1079478" "prognostic favorable (1.72e-5)" "unprognostic (1.43e-1)" "unprognostic (1.39e-2)" "unprognostic (2.37e-2)" "unprognostic (6.32e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (4.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.43e-2)" "unprognostic (3.36e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (1.37e-6)" "unprognostic (2.61e-2)" "unprognostic (8.83e-2)" "unprognostic (1.37e-2)" "prognostic favorable (8.07e-4)" 6.8 5.8 10.9 19.1 10.8 31.5 5.9 12.1 17.6 4.1 10.7 7.2 7.4 3.7 4.7 5.9 3.3 8.3 5.3 11.3 10.6 16.1 10.5 13.6 19.9 11.5 11.4 2.7 8.3 5.3 4.5 5.5 11.2 8.3 5.9 3.7 7.4 3.3 3.5 9.9 12.1 3.6 11.7 35.0 7.0 10.7 11.8 9.9 5.3 3.9 25.1 16.3 5.0 12.3 28.4 7.9 9.5 15.1 3.7 2.8 5.3 4.9 23.8 14.9 15.4 15.0 12.9 15.7 17.0 5.1 39.7 6.2 10.3 15.4 16.6 26.1 6.0 7.9 3.0 17.0 11.4 26.1 23.0 7.1 6.7 13.8 8.8 12.5 10.7 7.2 7.7 39.2 3.9 14.4 5.2 52.7 5.0 44.1 4.0 9.9 8.5 14.0 34.7 30.3 6.1 7.8 3.4 12.5 20.9 8.0 8.6 29.9 18.1 8.4 9.8 5.3 15.4 25.0 11.4 28.7 7.4 28.4 16.1 8.8 7.5 4.0 1.6 9.4 3.2 8.6 2.2 1.5 6.6 6.5 1.0 1.6 3.0 0.8 11.1 8.1 3.1 1.7 10.9 10.8 12.1 17.6 11.3 10.6 11.5 11.4 11.2 11.7 11.8 12.3 7.5 0.0 9.7 1.0 26.0 38.2 28.7 11.6 14.8 3.4 15.3 9.9 5.4 22.8 9.2 3.7 2.1 5.2 12.5 12.2 17.6 49.5 17.3 10.0 6.2 15.9 14.9 1.7 1.1 21.0 8.0 17.3 10.7 12.8 32.5 2.5 6.1 2.0 57.2 3.3 2.0 11.9 6.1 22.6 151.2 34.1 1.8 48.6 48.0 3.7 55.2 3.3 1.0 0.5 0.9 58.9 33.3 2.6 18.7 32.6 14.3 14.4 6.1 4.1 6.6 11.8 11.0 25.9 12.3 11.6 39.2 5.3 13.8 7.0 8.5 34.7 NGF NGFB ENSG00000134259 "Nerve growth factor" P01138 1 115285904-115338770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.8;ovary: 18.9" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 15.7;Leydig cells: 29.2;Sertoli cells: 118.3;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in many" "renal cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 87.9;BJ hTERT+ SV40 Large T+: 30.1;GAMG: 46.2;hTEC/SVTERT24-B: 29.8;hTERT-RPE1: 49.0;U-2197: 60.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted in other tissues" NA NA 40000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "unprognostic (7.55e-2)" "unprognostic (2.66e-2)" "unprognostic (1.53e-3)" "unprognostic (8.85e-2)" "unprognostic (4.12e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (5.30e-2)" "unprognostic (8.73e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.08e-7)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (7.99e-3)" "unprognostic (1.62e-4)" 13.9 2.5 1.7 1.6 1.7 0.0 4.0 1.3 2.1 7.1 2.1 5.0 0.1 8.8 1.4 1.1 13.2 1.7 20.8 1.6 2.2 6.4 4.0 1.6 0.5 1.9 1.7 18.9 0.8 0.4 2.7 1.1 1.9 2.6 0.6 0.1 2.1 1.0 0.9 0.9 2.1 4.0 1.4 3.7 2.1 1.1 1.9 0.2 3.3 1.1 0.1 5.5 5.0 1.6 0.0 0.3 0.0 0.0 1.8 0.1 0.0 87.9 9.9 30.1 21.9 0.0 0.0 0.0 1.9 21.1 46.2 3.6 0.0 0.6 13.8 0.0 0.2 0.0 0.6 0.0 12.1 0.0 0.0 0.1 0.6 29.8 21.6 49.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 3.0 0.0 1.3 0.0 1.2 0.0 0.0 0.0 1.1 0.3 1.6 0.6 0.0 3.9 0.0 0.0 0.8 1.8 3.7 60.0 3.5 0.0 0.0 0.0 3.6 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.7 1.3 2.1 1.6 2.2 1.9 1.7 1.9 1.4 1.9 1.6 0.4 0.0 0.0 0.3 0.0 3.1 0.5 3.9 0.0 0.0 0.1 1.5 0.7 1.5 0.2 0.0 0.0 3.0 0.0 0.0 0.0 5.6 0.2 0.2 0.8 0.8 0.0 0.0 0.3 0.0 1.3 7.3 0.0 0.3 0.0 0.0 4.2 0.0 0.1 0.0 15.7 0.0 2.0 0.0 1.7 0.4 29.2 0.2 1.8 1.9 0.0 0.0 0.0 12.1 0.5 0.1 0.0 6.0 0.0 0.6 0.0 0.0 0.1 0.0 118.3 0.8 51.6 0.3 1.0 0.0 2.3 2.5 0.6 0.0 0.0 0.3 NGFR "CD271, p75NTR, TNFRSF16" ENSG00000064300 "Nerve growth factor receptor" P08138 17 49495293-49515008 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Apoptosis, Biological rhythms, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.4;Basal squamous epithelial cells: 36.5;Ionocytes: 89.5;Leydig cells: 96.0;Muller glia cells: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.2" "Group enriched" "Detected in some" 7 "RH-30: 200.1;WM-115: 225.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 10.1" "CAB000143, CAB001995, HPA004765" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 490000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB000143: , CAB001995: , HPA004765: AB_1079233" "unprognostic (6.25e-3)" "unprognostic (1.06e-3)" "unprognostic (3.39e-3)" "unprognostic (6.67e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-1)" "unprognostic (8.22e-2)" "unprognostic (4.94e-2)" "unprognostic (1.08e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (4.01e-2)" "unprognostic (3.06e-2)" "unprognostic (2.77e-3)" "prognostic unfavorable (3.40e-4)" 36.8 20.7 4.1 8.2 12.1 0.4 20.3 17.3 63.6 13.1 1.4 16.8 2.4 12.0 4.0 6.5 20.2 9.4 40.9 3.2 25.1 8.0 22.8 2.9 5.0 16.9 15.2 4.1 10.9 1.3 10.5 14.7 15.1 19.1 2.4 45.1 21.2 7.6 4.8 15.9 8.0 8.2 10.9 23.0 7.9 7.7 17.2 2.0 28.9 1.3 3.9 15.3 13.2 27.8 0.0 0.1 6.3 10.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.1 0.0 2.1 0.1 3.4 4.8 1.5 4.6 0.0 0.4 0.7 0.4 0.0 3.8 0.4 0.3 0.3 20.9 0.3 0.6 1.5 0.1 0.0 0.0 0.0 0.1 29.5 0.6 0.0 0.1 3.8 0.0 0.2 3.9 200.1 0.2 0.0 0.0 1.9 1.3 0.1 0.0 14.0 7.4 0.4 0.2 0.0 0.1 3.4 0.6 10.2 0.2 0.3 0.1 0.2 1.9 225.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 4.1 12.1 17.3 63.6 3.2 25.1 16.9 15.2 15.1 10.9 17.2 27.8 1.2 0.0 0.0 0.0 1.1 3.6 33.1 52.4 36.5 4.8 2.4 10.9 0.7 0.0 3.8 0.0 4.2 0.5 4.0 0.0 0.0 0.1 0.7 0.2 0.6 1.3 0.0 0.0 0.1 0.0 0.5 7.3 0.5 0.2 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 89.5 0.0 3.1 2.9 96.0 0.7 16.0 0.0 0.0 151.7 0.0 0.0 6.5 0.0 0.0 27.8 1.0 3.7 0.0 0.1 1.7 7.0 32.9 1.7 12.9 0.4 0.9 1.8 1.7 0.1 2.3 0.4 0.0 2.9 NIBAN1 "C1orf24, FAM129A, GIG39, NIBAN" ENSG00000135842 "Niban apoptosis regulator 1" Q9BZQ8 1 184790724-184974508 "Cancer-related genes, Predicted intracellular proteins" "Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 164.1" "Cell type enriched" "Detected in some" 13 "Cardiomyocytes: 692.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 72.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 72.1" "Cell line enhanced" "Detected in many" "HDLM-2: 83.8;Karpas-707: 85.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028172, HPA028231, HPA028657" Approved Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA028172: AB_10599602, HPA028231: AB_10601886, HPA028657: AB_10601680" "unprognostic (4.61e-3)" "unprognostic (3.45e-2)" "unprognostic (1.64e-3)" "unprognostic (9.46e-2)" "unprognostic (2.77e-1)" "unprognostic (3.87e-1)" "unprognostic (3.23e-2)" "unprognostic (1.30e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (4.12e-1)" "unprognostic (1.32e-1)" "unprognostic (2.94e-3)" "unprognostic (9.01e-3)" "unprognostic (4.38e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (4.52e-4)" 18.2 7.8 1.4 38.9 1.6 8.8 24.0 1.5 1.9 14.8 3.1 104.7 8.5 24.2 6.2 61.2 22.1 27.7 164.1 1.5 2.0 3.3 2.7 18.1 11.3 3.9 2.4 4.9 85.7 4.2 2.1 6.2 3.1 59.6 15.9 0.8 100.6 43.1 60.9 8.8 18.5 41.0 2.8 12.3 58.9 1.9 2.2 12.2 15.3 41.2 17.3 105.8 14.6 3.2 42.0 0.5 0.2 0.1 28.0 42.2 1.6 21.1 42.9 17.7 22.3 0.0 17.3 0.0 13.6 54.2 4.6 46.0 2.4 1.5 28.4 83.8 3.2 17.5 8.2 0.0 65.2 57.2 19.1 39.1 65.3 52.1 62.4 12.6 0.1 6.3 4.2 85.5 0.5 0.2 1.9 10.0 11.1 0.0 4.3 13.3 9.9 0.8 24.5 0.8 2.3 2.1 0.4 0.1 29.9 7.0 9.0 17.9 3.3 35.0 0.1 6.3 43.5 71.1 30.2 8.7 68.8 23.4 35.3 20.4 3.6 10.9 5.1 2.1 4.4 1.0 4.7 5.0 5.2 0.3 0.4 1.8 72.1 5.7 0.8 0.5 11.9 2.2 1.4 1.6 1.5 1.9 1.5 2.0 3.9 2.4 3.1 2.8 2.2 3.2 20.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 692.7 0.0 0.0 0.0 0.0 0.4 52.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.2 24.7 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.4 27.4 0.0 0.0 0.0 NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 240.5;Muller glia cells: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005939, HPA070691" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim, Centrosome" Nucleoplasm "HPA005939: AB_2667474, HPA070691: AB_2686296" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (3.54e-2)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (3.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (2.07e-1)" "unprognostic (4.06e-1)" "unprognostic (2.46e-2)" "unprognostic (2.67e-1)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (7.66e-3)" 11.2 4.4 10.1 19.9 10.8 43.2 8.9 9.5 15.0 7.2 0.0 8.3 4.8 7.7 2.8 12.9 10.5 8.9 18.2 10.4 0.9 6.7 5.7 9.5 25.9 0.0 1.3 9.7 7.2 9.0 8.9 16.8 0.0 6.9 8.6 19.1 5.4 5.4 6.0 12.9 7.1 10.3 0.0 16.2 9.3 5.2 3.0 19.9 7.7 7.4 23.7 13.6 5.7 7.5 29.1 21.6 42.4 36.8 16.7 26.8 20.4 26.5 22.1 21.4 18.0 14.7 14.6 48.5 17.7 35.5 19.9 32.5 34.2 16.3 45.3 34.7 10.4 25.1 13.2 12.3 9.8 41.6 57.5 18.4 11.4 37.2 14.9 13.3 34.6 25.9 6.6 26.3 31.8 36.8 22.6 14.0 6.4 10.1 23.6 37.1 81.6 5.7 20.1 42.9 18.6 22.2 34.0 9.6 25.1 10.2 21.2 39.3 50.9 55.2 74.3 20.5 29.0 18.6 12.1 34.3 14.4 32.8 30.4 31.9 2.9 24.0 3.9 2.5 3.3 8.9 2.4 6.2 2.0 6.2 5.1 4.7 9.6 2.9 2.1 7.7 2.5 1.4 10.1 10.8 9.5 15.0 10.4 0.9 0.0 1.3 0.0 0.0 3.0 7.5 34.0 6.4 7.7 100.2 85.6 18.4 9.1 10.2 18.8 13.3 13.3 10.9 68.0 14.3 27.1 11.0 62.6 12.4 102.7 8.7 3.9 7.3 22.2 17.3 28.5 26.7 12.6 29.0 240.5 4.2 11.3 32.9 7.7 14.9 31.6 3.9 21.8 4.4 22.7 6.7 110.4 5.7 20.3 46.8 42.2 10.4 8.4 61.3 23.2 63.7 63.2 150.2 57.7 105.6 75.1 5.2 6.2 9.4 48.1 16.5 3.2 7.3 29.4 21.0 32.9 44.9 24.1 0.2 4.3 20.1 21.0 9.7 56.2 21.8 6.9 15.5 NKX2-1 "BCH, NKX2A, TITF1, TTF-1, TTF1" ENSG00000136352 "NK2 homeobox 1" P43699 14 36516392-36521149 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lung: 53.1;thyroid gland: 172.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 137.8;Alveolar cells type 2: 124.8" "Group enriched" "Detected in some" 39 "lung cancer: 30.9;thyroid cancer: 103.2" "Region enhanced" "Detected in many" "thalamus: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SCLC-21H: 78.7" "Group enriched" "Detected in some" 5 "basal ganglia: 3.2;hypothalamus: 10.2" "Group enriched" "Detected in some" 13 "basal ganglia: 4.3;hypothalamus: 10.4" "CAB000078, CAB053633, HPA074316" Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus, Vesicles" "CAB000078: , CAB053633: AB_442138, HPA074316: " "unprognostic (3.79e-1)" "unprognostic (4.25e-3)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" "unprognostic (1.26e-2)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (1.29e-1)" "unprognostic (1.83e-2)" "unprognostic (4.18e-1)" 0.0 0.1 1.1 0.0 2.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 10.1 0.0 0.0 53.1 0.0 0.0 0.3 0.1 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 17.8 0.0 172.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 78.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.0 4.0 0.1 10.1 0.0 0.3 0.0 0.0 17.8 0.1 0.0 137.8 124.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 NKX3-1 "BAPX2, NKX3.1, NKX3A" ENSG00000167034 "NK3 homeobox 1" Q99801 8 23678697-23682938 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "prostate: 303.3" "Group enriched" "Detected in many" 6 "Basal prostatic cells: 51.0;Prostatic glandular cells: 124.8" "Cancer enriched" "Detected in many" 65 "prostate cancer: 392.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 54.0;neutrophil: 51.6" "Lineage enriched" "Detected in many" 21 "granulocytes: 54.0" "Cell line enhanced" "Detected in many" "GAMG: 25.7;SiHa: 26.1;U-138 MG: 25.8;U-251 MG: 23.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA025693, HPA078571" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA025693: AB_1854522, HPA078571: AB_2732384" "unprognostic (1.47e-2)" "unprognostic (4.03e-2)" "unprognostic (2.67e-1)" "unprognostic (5.87e-2)" "unprognostic (2.56e-6)" "unprognostic (6.90e-3)" "unprognostic (1.13e-1)" "unprognostic (4.11e-3)" "unprognostic (9.42e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.37e-2)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.09e-2)" "unprognostic (1.69e-1)" 1.7 3.9 1.0 1.5 1.2 2.2 2.1 1.4 1.4 1.1 0.9 1.4 1.4 1.5 1.3 3.7 1.8 1.1 2.6 1.2 1.6 1.4 4.1 1.4 1.2 1.8 1.5 2.8 1.8 1.0 0.9 0.8 1.6 303.3 0.5 1.7 62.0 1.8 3.2 0.4 1.0 1.9 1.7 0.8 1.4 24.0 1.5 0.5 0.7 3.9 1.6 2.9 1.9 1.4 4.9 3.7 0.0 8.7 3.1 0.7 7.1 6.7 4.2 13.8 16.2 2.1 5.5 0.0 1.0 5.0 25.7 1.2 3.5 7.6 10.9 0.0 1.8 3.4 2.6 5.5 6.0 0.0 1.2 1.2 2.0 14.0 0.8 8.5 0.7 20.1 0.2 0.0 5.5 1.6 11.8 1.0 2.0 0.0 2.6 0.0 5.5 0.5 0.8 5.7 1.6 0.4 26.1 4.8 0.4 9.9 3.5 0.5 0.9 25.8 9.1 2.0 23.0 0.0 0.0 0.0 12.5 2.6 3.2 10.2 0.0 54.0 1.0 0.1 0.2 2.2 0.4 1.0 0.1 1.8 1.4 2.5 51.6 0.6 0.1 0.0 0.0 0.3 1.0 1.2 1.4 1.4 1.2 1.6 1.8 1.5 1.6 1.7 1.5 1.4 6.0 3.2 5.3 0.0 4.1 5.6 51.0 4.1 4.6 3.7 13.5 6.5 9.8 1.5 4.7 0.0 8.4 0.3 0.3 1.0 0.0 2.7 2.7 1.3 2.0 6.8 6.6 0.0 0.4 7.0 1.4 9.1 5.1 2.2 0.0 0.8 4.6 4.9 0.3 3.3 0.4 1.2 2.0 0.3 9.4 6.1 2.1 2.5 1.8 0.0 0.6 4.9 0.0 0.5 0.1 5.2 0.1 6.4 1.0 124.8 0.4 0.7 1.4 4.5 0.0 11.4 5.1 1.8 2.1 2.5 2.0 0.3 2.5 0.8 1.1 12.2 NLRP3 "AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1" ENSG00000162711 "NLR family pyrin domain containing 3" Q96P20 1 247416156-247449108 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" Activator "Amyloidosis, Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 53.8" "Cell type enriched" "Detected in many" 6 "Macrophages: 254.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 129.4" "Group enriched" "Detected in many" 23 "dendritic cells: 37.3;granulocytes: 129.4;monocytes: 35.6" "Cell line enriched" "Detected in some" 4 "THP-1: 78.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012878 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA012878: AB_1846752" "unprognostic (3.56e-2)" "unprognostic (1.33e-1)" "unprognostic (6.23e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (7.86e-2)" "unprognostic (4.46e-2)" "unprognostic (3.84e-1)" "unprognostic (7.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.11e-1)" "unprognostic (1.52e-2)" "unprognostic (4.88e-3)" "unprognostic (2.17e-4)" "unprognostic (1.10e-1)" "unprognostic (6.10e-2)" 8.3 1.4 1.0 10.0 0.8 53.8 3.5 0.8 1.0 1.8 0.8 1.5 0.8 0.9 0.4 2.7 1.4 6.5 1.0 0.9 1.6 0.6 2.1 4.6 2.5 2.0 1.4 0.7 1.6 0.9 0.5 3.4 2.1 0.8 1.8 0.3 0.8 0.7 0.5 0.4 2.4 4.8 1.9 4.6 1.4 0.3 1.6 1.7 1.0 0.5 1.7 6.4 0.4 3.4 7.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.9 0.2 0.4 0.0 0.3 0.0 0.3 0.0 0.5 0.0 0.0 2.2 2.9 0.5 0.0 1.3 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.8 0.0 0.0 0.4 0.4 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 78.4 0.1 3.2 2.5 0.0 0.2 0.0 0.0 0.0 7.2 18.9 2.4 129.4 35.6 0.2 0.6 21.7 1.7 0.0 2.9 1.2 37.3 0.1 1.1 0.7 8.6 0.0 11.5 1.8 0.1 12.2 1.0 0.8 0.8 1.0 0.9 1.6 2.0 1.4 2.1 1.9 1.6 3.4 2.2 0.0 0.5 0.3 2.6 1.0 0.1 0.0 0.6 0.3 0.6 1.1 0.6 0.0 0.0 0.0 0.0 0.7 6.0 0.0 0.0 0.0 0.3 0.1 0.5 2.3 0.0 1.7 2.6 0.0 0.4 1.2 1.5 0.1 2.5 0.2 0.4 0.3 16.2 0.0 1.2 0.2 0.0 35.4 41.4 0.2 0.0 254.2 0.0 17.8 14.5 0.7 1.0 1.0 0.4 0.1 0.0 0.4 4.0 0.0 0.0 0.2 0.0 0.4 0.0 1.0 1.1 0.4 0.4 1.3 0.6 1.4 10.2 0.1 0.0 0.0 NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153559-51162428 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 21000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB040571: , HPA008467: AB_1079492, HPA041113: AB_2677305" "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" 63.6 84.4 79.3 74.7 81.6 77.0 63.1 78.7 102.2 38.2 79.0 60.1 38.8 49.7 46.8 91.0 48.6 20.8 37.7 88.0 92.0 65.4 83.2 41.3 73.9 83.9 78.4 33.6 67.8 52.8 47.4 39.2 82.4 38.7 77.6 218.4 50.7 30.4 35.6 57.5 33.1 66.3 76.5 48.5 41.8 25.3 81.0 61.1 41.3 20.9 95.8 72.2 48.9 80.1 483.6 833.1 285.9 444.8 118.6 183.7 479.7 355.3 227.3 652.2 489.7 656.9 288.1 754.2 372.4 304.1 272.4 252.1 542.5 553.3 553.4 398.4 729.3 504.9 605.8 975.9 237.1 575.8 243.8 177.8 341.7 493.1 458.6 120.6 404.6 247.8 739.0 270.0 392.8 720.4 715.2 647.1 390.7 957.5 739.3 446.9 587.6 751.3 511.5 320.2 418.6 461.1 188.1 521.0 385.3 246.2 554.0 419.6 279.5 476.9 452.2 307.0 774.4 374.0 840.9 956.3 286.2 480.4 385.8 1.1 55.0 2.1 47.2 77.1 69.3 96.4 50.3 53.8 134.0 67.6 54.3 60.4 1.7 69.6 48.6 84.8 49.1 68.4 79.3 81.6 78.7 102.2 88.0 92.0 83.9 78.4 82.4 76.5 81.0 80.1 53.1 32.1 30.5 0.0 71.3 132.4 97.5 198.8 88.8 283.3 98.8 118.1 34.2 65.8 92.3 71.7 285.7 180.0 25.4 54.2 150.6 211.3 34.2 40.2 107.2 85.1 89.7 81.8 0.0 201.5 269.7 85.0 64.2 37.2 45.7 113.5 27.8 123.3 207.1 40.4 0.0 107.4 101.7 25.7 88.9 93.7 61.2 48.9 129.9 0.0 47.2 105.6 27.8 0.0 0.0 194.0 50.5 58.6 113.8 170.6 12.2 195.2 42.0 323.7 13.1 83.0 182.9 22.7 98.8 139.4 133.1 88.5 38.0 215.5 157.7 98.2 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 918.0;Gastric mucus-secreting cells: 438.3;Plasma cells: 778.5;Squamous epithelial cells: 1490.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported "Plasma membrane,Midbody ring,Cytosol" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane, Midbody ring" "CAB036213: , CAB036214: , CAB036215: , HPA041113: AB_2677305" "unprognostic (7.21e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 503.5 428.3 308.0 259.5 319.0 329.4 489.1 328.0 379.9 439.2 431.1 409.2 335.1 383.4 236.1 610.6 350.6 187.0 403.9 313.7 338.6 478.1 428.4 339.6 288.9 326.6 320.7 500.1 632.0 201.8 234.9 204.8 321.3 367.7 330.4 63.3 432.4 247.5 545.7 540.3 307.6 286.2 326.8 336.0 403.5 77.8 333.3 190.0 305.3 353.7 289.1 463.5 464.2 333.4 1638.6 2233.9 466.1 913.7 969.3 1399.2 1449.2 1091.7 954.0 1404.8 1053.5 1789.7 792.3 1314.3 1662.9 913.0 706.6 956.2 947.3 1273.3 1035.7 1604.8 3283.2 1120.3 1345.8 2513.4 1116.1 1736.0 760.5 1324.1 1420.0 901.9 1466.4 914.6 860.9 856.5 1541.7 773.7 956.1 2741.9 931.3 2144.8 831.4 2974.6 3364.2 875.9 1731.8 2157.2 1417.9 1800.2 1160.6 641.9 674.1 1472.7 1583.0 806.1 1201.7 1268.5 1013.5 1462.8 1158.2 1135.2 1774.8 1520.9 2176.6 1558.1 815.1 919.1 819.2 66.8 243.4 14.0 166.7 325.5 235.6 338.9 211.9 183.3 439.5 259.2 153.5 170.0 13.8 251.6 282.5 478.1 211.2 298.2 308.0 319.0 328.0 379.9 313.7 338.6 326.6 320.7 321.3 326.8 333.3 333.4 9.7 28.9 67.2 0.0 146.8 14.5 8.3 10.8 918.0 0.9 41.6 35.9 0.0 22.8 85.7 5.5 0.0 10.0 10.1 7.1 37.2 47.4 0.6 16.4 34.3 60.9 14.6 298.2 0.0 34.5 27.8 99.0 438.3 21.3 42.9 6.8 22.9 37.6 16.4 0.0 0.0 19.3 8.2 34.8 17.4 2.1 25.7 136.7 10.6 0.0 55.5 0.4 2.1 0.0 0.0 40.7 15.6 12.8 778.5 7.6 11.7 33.8 63.6 0.8 6.6 10.2 43.3 0.6 5.6 1490.1 14.9 8.8 87.0 6.8 25.0 11.0 NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Nuclear speckles" NA NA 450000 "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Nuclear speckles" "CAB022069: , HPA054094: AB_2682376, HPA054559: AB_2682522" "unprognostic (2.39e-3)" "unprognostic (2.22e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (8.87e-2)" "unprognostic (5.54e-2)" "unprognostic (1.02e-3)" "unprognostic (9.34e-2)" "unprognostic (2.32e-2)" "unprognostic (1.41e-2)" "unprognostic (3.12e-1)" "unprognostic (2.07e-1)" "unprognostic (7.29e-3)" "unprognostic (6.79e-2)" "unprognostic (5.73e-3)" "unprognostic (2.76e-2)" "unprognostic (3.04e-2)" 106.4 147.2 58.6 96.4 57.7 115.3 109.2 71.5 64.9 116.8 64.4 101.3 86.2 130.2 107.9 111.9 115.4 100.7 81.2 55.3 69.9 103.3 121.5 103.2 136.5 60.3 61.5 197.9 164.8 114.8 97.1 99.1 60.5 97.0 101.2 70.2 106.8 89.6 99.1 112.2 102.0 113.5 59.2 109.5 114.3 55.2 68.5 255.5 116.0 86.1 165.2 116.8 102.6 61.0 421.2 539.7 595.3 344.4 251.2 238.5 345.3 330.9 319.2 459.3 388.5 413.4 312.9 481.4 379.9 320.5 309.7 310.5 949.5 299.4 488.1 383.9 605.7 394.8 498.4 398.0 212.3 547.7 338.7 272.0 206.0 473.1 305.7 370.5 382.0 342.1 535.3 509.0 406.2 413.9 756.0 466.8 771.3 433.9 365.2 660.0 657.3 414.0 345.9 426.1 431.7 519.4 467.8 299.1 392.5 354.9 271.4 354.0 343.9 268.0 438.6 402.9 400.1 297.3 503.2 516.0 216.8 627.1 433.8 107.5 117.3 91.1 107.9 120.0 119.9 107.4 107.9 106.4 118.7 107.2 115.1 115.6 50.8 119.6 140.7 101.1 128.0 178.1 58.6 57.7 71.5 64.9 55.3 69.9 60.3 61.5 60.5 59.2 68.5 61.0 72.9 76.9 81.1 16.3 97.2 126.3 99.9 105.8 116.7 62.3 111.4 83.6 63.5 90.1 99.8 44.1 41.7 132.3 103.6 52.0 56.7 147.8 11.8 81.6 137.8 95.4 139.8 144.6 16.2 111.4 179.9 93.9 71.4 104.8 88.0 135.9 83.9 128.3 112.6 53.8 20.7 105.6 95.6 153.2 107.7 15.9 106.6 95.0 56.9 13.1 132.0 84.8 96.8 19.6 22.8 110.7 75.4 127.9 115.2 94.9 89.0 121.0 71.1 50.3 65.7 78.7 127.8 45.7 66.5 137.3 122.3 130.1 108.5 163.7 117.2 103.0 NOS1 "nNOS, NOS" ENSG00000089250 "Nitric oxide synthase 1" P29475 12 117208142-117452170 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 23.0;skeletal muscle: 36.9;tongue: 57.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 10.0;Hepatic stellate cells: 18.2;Inhibitory neurons: 32.1;Oligodendrocyte precursor cells: 48.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4.6;RH-30: 9.4;RPTEC TERT1: 5.8;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002167, HPA058312, HPA069509" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "CAB002167: AB_564073, HPA058312: AB_2683676, HPA069509: " "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.18e-2)" "unprognostic (6.64e-3)" "unprognostic (4.91e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-1)" "unprognostic (9.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (7.56e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-4)" "unprognostic (1.87e-1)" 0.1 0.1 12.7 0.4 12.4 0.2 0.1 5.7 7.0 0.3 0.0 2.2 0.1 0.1 0.2 0.8 0.3 0.0 0.0 4.0 16.2 1.3 0.0 0.8 0.1 12.1 11.0 0.0 1.4 0.0 0.9 0.0 12.2 0.9 0.4 0.3 3.4 0.1 36.9 1.9 0.4 0.3 2.3 0.0 0.2 0.5 23.0 0.0 0.1 57.2 0.1 0.0 0.7 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 9.4 0.0 5.8 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 12.7 12.4 5.7 7.0 4.0 16.2 12.1 11.0 12.2 2.3 23.0 3.3 0.0 0.0 0.0 1.3 0.0 3.8 10.0 2.4 4.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.0 3.0 5.1 0.4 3.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 8.4 0.0 0.0 18.2 0.0 0.0 0.0 32.1 0.2 0.0 0.3 0.7 0.6 0.3 0.2 1.8 1.9 0.0 0.0 0.0 48.2 5.7 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.1 1.8 0.1 0.6 0.0 0.2 0.0 0.0 1.0 NOS2 "HEP-NOS, iNOS, NOS, NOS2A" ENSG00000007171 "Nitric oxide synthase 2" P35228 17 27756766-27800529 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 21.1;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 40.3;Extravillous trophoblasts: 27.7;Granulosa cells: 57.3;Proximal enterocytes: 10.7;Undifferentiated cells: 10.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "CACO-2: 16.5;SCLC-21H: 13.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002014 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB002014: " "unprognostic (1.95e-3)" "unprognostic (3.08e-3)" "unprognostic (4.75e-3)" "unprognostic (4.42e-3)" "unprognostic (3.49e-1)" "unprognostic (2.13e-2)" "unprognostic (5.61e-2)" "unprognostic (5.09e-2)" "unprognostic (9.91e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "unprognostic (1.34e-1)" "unprognostic (6.04e-2)" "unprognostic (8.02e-2)" "unprognostic (3.68e-1)" "unprognostic (8.69e-2)" "unprognostic (4.03e-2)" 0.9 0.5 0.2 14.4 0.5 0.0 0.3 0.1 2.1 0.3 0.0 6.8 12.1 0.2 0.0 0.7 0.4 0.4 0.4 0.7 0.2 1.6 0.1 1.8 0.8 0.3 0.1 0.6 0.3 0.1 1.3 0.6 0.5 0.6 8.9 0.2 0.1 0.2 0.8 0.2 21.1 1.8 0.1 0.1 0.1 0.3 1.0 0.1 0.4 0.7 0.1 3.6 0.2 0.9 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.9 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 2.1 0.7 0.2 0.3 0.1 0.5 0.1 1.0 0.9 1.2 0.0 0.0 1.3 0.6 0.0 0.2 3.6 0.0 0.5 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.2 0.0 40.3 0.0 0.0 0.2 0.0 0.0 0.7 2.4 0.0 4.1 0.0 27.7 0.2 0.0 0.1 0.0 57.3 0.0 0.0 0.7 0.0 2.2 3.8 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 4.9 0.4 0.0 1.4 10.7 0.1 0.5 0.1 0.0 0.3 1.2 0.0 1.5 0.0 0.0 0.5 0.3 0.1 10.2 1.0 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.2;Astrocytes: 67.3;Hepatic stellate cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 47.0;HDLM-2: 32.3;HMC-1: 39.7;MOLT-4: 72.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" 18.2 4.2 10.4 4.9 16.1 4.3 15.0 12.1 9.3 14.3 0.0 19.8 4.3 12.7 0.2 16.3 11.9 0.9 14.9 8.6 5.5 11.8 9.2 22.2 3.0 13.5 12.3 5.1 14.0 0.7 6.3 2.6 9.8 15.4 0.6 0.6 10.7 3.1 5.0 24.2 14.2 1.3 9.7 24.8 10.0 2.5 13.9 4.0 11.2 1.2 0.9 14.2 16.5 14.0 8.8 10.6 4.0 2.6 0.0 0.4 17.7 3.3 0.4 1.4 0.4 1.8 0.9 13.3 10.3 1.3 1.6 47.0 1.0 8.6 0.1 32.3 2.0 5.5 6.1 0.6 2.1 6.9 39.7 0.3 16.7 1.4 1.9 0.7 9.0 3.7 3.6 1.1 0.0 9.0 72.3 13.1 8.4 2.9 7.7 15.7 9.2 19.3 0.6 4.2 0.0 0.7 6.1 4.3 3.4 1.0 3.2 10.4 22.7 5.0 9.3 5.9 4.3 2.4 2.6 4.1 3.7 5.0 26.1 0.2 0.4 0.6 0.3 0.1 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.3 2.3 0.7 0.1 0.1 0.1 0.5 10.4 16.1 12.1 9.3 8.6 5.5 13.5 12.3 9.8 9.7 13.9 14.0 56.2 9.6 21.9 67.3 8.4 24.9 12.3 35.1 23.9 0.8 10.7 12.4 11.0 5.7 16.3 1.8 2.1 1.1 14.2 11.8 0.0 5.1 0.3 12.3 9.9 53.2 2.4 5.2 0.3 4.0 2.2 6.4 1.1 17.3 34.9 1.0 68.2 7.7 9.3 1.7 0.4 14.8 18.3 10.1 17.5 0.3 1.2 15.2 7.2 18.7 14.3 46.6 24.7 33.7 19.6 2.1 11.5 0.7 5.7 8.4 4.1 3.4 3.8 2.0 6.6 14.7 18.4 0.2 3.3 20.6 29.8 1.1 15.0 1.4 28.8 15.6 NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" 27.1 12.9 16.4 20.4 13.6 13.7 24.8 11.9 16.4 31.0 20.3 16.0 5.4 21.2 20.8 24.9 25.7 18.5 14.2 15.9 13.7 10.9 19.6 20.2 16.7 20.6 18.6 33.9 20.1 12.1 5.5 24.9 13.9 20.4 13.6 19.3 17.1 22.2 6.4 32.3 11.9 26.6 15.7 25.3 10.5 25.4 19.3 15.3 21.2 8.9 17.9 19.0 24.1 14.8 54.2 17.7 27.0 20.7 108.5 92.7 26.6 39.7 54.8 51.8 55.8 16.3 14.2 1.4 32.6 75.3 46.2 20.1 42.8 35.3 82.5 64.0 27.2 32.1 45.7 1.6 40.5 32.7 8.0 75.5 22.5 155.2 103.7 78.4 26.9 14.5 0.8 65.3 63.7 59.2 13.9 9.2 34.6 5.0 19.6 9.1 94.2 36.1 27.3 33.4 1.1 13.4 54.5 50.0 27.9 53.4 28.0 11.7 97.0 67.0 45.8 102.7 63.1 27.9 16.8 16.5 98.7 29.5 65.2 15.0 14.9 22.9 1.4 7.3 1.4 39.0 1.6 0.9 23.7 33.3 3.1 2.0 8.9 2.4 10.5 12.3 3.8 4.4 16.4 13.6 11.9 16.4 15.9 13.7 20.6 18.6 13.9 15.7 19.3 14.8 4.6 35.3 19.5 125.4 36.6 46.3 56.6 14.8 31.3 3.3 38.1 25.3 16.0 24.3 28.5 18.4 6.2 1.6 26.0 6.2 0.0 46.8 17.7 33.8 21.9 5.4 6.1 18.3 4.2 12.9 8.9 67.8 5.1 61.1 15.8 78.3 3.9 41.5 32.7 3.3 22.6 7.9 20.3 74.7 78.2 12.6 55.0 76.6 39.2 43.1 79.3 46.2 15.5 75.4 0.6 26.8 105.5 85.4 14.2 37.2 3.2 4.9 16.4 10.5 19.7 83.6 34.0 10.0 4.3 75.1 88.9 1.6 18.5 22.0 15.8 66.9 NOTCH3 "CADASIL, CASIL" ENSG00000074181 "Notch receptor 3" Q9UM47 19 15159038-15200995 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 414.2;Skeletal myocytes: 131.6;Smooth muscle cells: 317.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;MCF7: 66.9;RT4: 41.2;U-87 MG: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005393, HPA044392" Approved Supported "Nucleoplasm,Actin filaments,Cytosol" NA NA 46000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Actin filaments" "CAB005393: AB_2151246, HPA044392: AB_2678926" "unprognostic (4.97e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-3)" "prognostic unfavorable (5.92e-4)" "unprognostic (9.20e-2)" "unprognostic (1.73e-2)" "unprognostic (2.72e-1)" "unprognostic (9.04e-2)" "unprognostic (3.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-1)" "unprognostic (3.13e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (3.35e-2)" "unprognostic (8.34e-3)" "unprognostic (4.40e-2)" "unprognostic (2.00e-3)" 85.7 5.3 14.8 10.4 12.4 0.2 50.5 11.0 21.3 49.4 7.1 14.8 5.5 39.9 16.9 74.3 35.8 23.5 43.6 9.5 11.3 26.0 3.2 38.3 9.2 12.0 15.2 18.9 10.7 12.6 10.3 59.8 14.3 22.0 4.2 0.5 24.4 16.5 29.7 82.1 14.3 16.9 8.2 15.0 11.6 3.8 15.8 34.1 32.3 25.1 10.4 26.3 55.1 10.0 13.0 8.1 66.3 30.3 9.2 7.3 29.8 10.2 0.4 0.4 0.3 15.6 13.4 0.4 7.7 18.9 0.1 15.1 12.1 0.2 0.6 0.1 3.1 0.4 12.4 3.5 4.5 0.0 1.2 8.4 7.3 15.5 1.6 0.6 0.8 4.6 0.5 0.6 1.2 66.9 15.9 0.1 38.8 11.2 0.0 0.1 3.7 0.3 0.0 41.2 1.9 21.4 0.1 37.8 0.0 19.6 40.3 0.1 0.0 1.9 21.0 0.3 0.1 0.1 0.7 0.0 45.7 0.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 14.8 12.4 11.0 21.3 9.5 11.3 12.0 15.2 14.3 8.2 15.8 10.0 39.6 9.6 1.5 5.9 0.4 24.1 7.8 17.8 4.6 0.4 41.5 30.7 60.7 0.0 28.5 16.5 0.0 20.2 1.0 0.0 5.9 14.8 0.5 4.8 13.5 32.0 0.0 0.0 0.6 0.0 3.9 24.2 2.0 11.8 0.0 5.9 4.2 0.0 2.8 0.0 0.3 0.3 6.1 10.4 12.3 0.1 9.0 4.1 17.8 13.1 0.7 0.8 0.0 0.0 0.2 0.9 0.1 11.7 0.0 13.0 0.1 0.0 4.2 0.8 414.2 131.6 317.0 0.9 1.2 72.1 72.2 31.5 2.0 1.2 0.2 36.0 NPM1 "B23, NPM" ENSG00000181163 "Nucleophosmin 1" P06748 5 171387116-171411810 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011384, CAB012983" Supported Enhanced "Nucleoplasm,Nucleoli rim" NA Yes 2000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Nucleoli rim" Nucleoplasm "CAB012983: AB_2533084, HPA011384: AB_1854692" "unprognostic (1.84e-3)" "unprognostic (2.59e-1)" "unprognostic (2.23e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (7.48e-4)" "prognostic unfavorable (4.82e-6)" "unprognostic (1.86e-2)" "unprognostic (5.25e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.24e-2)" 515.1 370.6 180.7 468.4 190.3 789.2 597.1 188.6 233.5 759.2 195.9 486.6 347.1 656.6 421.5 623.0 596.1 355.4 336.7 169.0 210.7 375.3 370.3 364.5 777.0 196.2 188.6 1384.6 810.6 278.0 314.4 423.7 207.5 386.2 421.2 161.3 385.2 318.5 450.9 386.6 374.1 436.0 213.9 358.1 467.8 284.7 202.6 683.3 510.1 282.4 761.7 524.9 565.4 204.5 2476.2 1522.7 1864.0 2663.1 1073.3 1915.6 2736.9 2111.3 1826.0 2678.1 2387.2 3640.2 1622.2 6243.9 1683.2 1194.5 1927.6 1386.6 2552.2 4639.2 3423.4 2027.9 2027.3 2149.1 1361.9 2740.2 1593.2 4556.3 1790.7 1732.2 1559.7 1845.8 3572.3 2184.3 2019.4 1460.9 2712.8 1406.5 1945.5 2826.5 3071.1 3087.4 2400.7 1280.7 1857.2 2695.2 2051.7 3241.9 2306.9 1583.1 1433.8 1167.4 1210.6 2084.4 4091.0 1288.7 2513.8 2000.7 1289.5 916.7 2114.4 1082.5 3705.3 1161.5 2139.6 3702.2 1403.3 3561.5 1897.0 153.6 287.1 92.3 443.1 311.4 834.2 847.9 832.8 654.3 564.2 634.9 1189.9 973.4 38.0 656.2 264.4 516.8 782.6 1076.1 180.7 190.3 188.6 233.5 169.0 210.7 196.2 188.6 207.5 213.9 202.6 204.5 462.2 346.1 461.1 12.4 911.0 1400.1 1224.1 1692.5 993.1 177.2 779.0 1045.4 243.5 514.8 764.5 323.7 43.8 1647.8 615.9 175.3 743.4 1073.6 135.8 466.3 707.3 568.2 362.1 865.5 15.6 919.2 2021.0 685.9 489.8 544.6 443.8 688.8 383.8 254.1 1071.0 127.9 20.3 656.0 679.5 629.2 817.6 98.6 974.9 557.2 610.1 19.7 862.8 339.2 476.8 14.6 21.2 922.5 370.1 649.9 671.6 1051.5 404.2 911.0 357.4 144.1 433.9 617.8 1074.1 855.7 578.6 907.2 1019.1 1538.8 865.1 1019.5 866.2 967.3 NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726668 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 522.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 539.8;Respiratory ciliated cells: 471.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 2434.0;OE19: 4177.0;SiHa: 2756.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007308, CAB012421" Enhanced Supported Cytosol NA NA 490000 "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "CAB012421: , HPA007308: AB_1079501" "unprognostic (1.04e-2)" "unprognostic (1.95e-3)" "unprognostic (3.14e-1)" "unprognostic (3.76e-3)" "unprognostic (9.03e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.05e-3)" "unprognostic (1.97e-1)" "unprognostic (5.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-2)" "unprognostic (6.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.27e-1)" 100.9 95.1 88.9 20.7 97.2 0.8 264.8 88.1 165.6 24.3 113.4 85.6 106.8 16.1 27.2 162.2 29.3 183.1 24.3 86.7 95.0 93.9 5.6 36.5 4.8 83.5 86.2 8.9 9.2 19.5 15.3 12.0 85.9 20.7 74.0 21.4 47.7 25.1 34.2 11.7 56.1 35.0 83.0 22.8 522.7 6.4 93.6 4.3 112.7 27.0 16.5 79.0 34.2 86.8 224.2 2434.0 203.4 901.3 473.1 682.7 77.5 363.1 632.7 363.9 547.0 302.0 1395.7 7.1 433.1 1850.6 634.3 232.1 79.1 410.3 185.2 91.3 3.3 10.9 564.4 2169.9 631.7 53.8 170.6 166.2 246.8 642.8 74.4 537.9 903.9 18.5 95.3 16.3 1914.1 725.9 11.6 98.7 107.0 4177.0 237.1 18.9 44.0 101.6 708.3 781.5 73.0 17.2 2756.6 384.8 1690.4 226.6 631.3 173.1 626.5 368.8 155.8 140.0 297.1 12.7 53.1 11.2 470.2 29.1 1864.0 1.1 3.9 0.3 6.3 0.4 3.1 5.7 7.3 8.3 3.8 2.4 2.2 5.3 0.9 18.7 0.4 1.3 15.6 5.1 88.9 97.2 88.1 165.6 86.7 95.0 83.5 86.2 85.9 83.0 93.6 86.8 88.5 25.6 14.6 8.8 2.9 5.2 26.4 185.5 32.5 10.0 31.1 30.5 4.8 138.7 90.9 42.3 4.2 1.7 3.5 165.7 146.8 25.6 0.4 117.2 11.7 81.0 20.4 1.3 1.9 147.5 4.3 32.9 539.8 65.7 19.7 10.1 28.5 2.6 15.2 3.3 1.6 81.7 107.8 3.5 7.6 1.2 25.1 10.9 17.8 4.7 128.5 10.6 7.2 0.0 5.0 75.1 59.4 12.0 2.3 22.6 62.9 44.3 471.3 15.1 6.6 21.1 72.1 0.3 1.3 128.3 4.5 1.9 5.6 17.3 51.5 40.6 NR0B1 "AHC, AHCH, DAX1, DSS" ENSG00000169297 "Nuclear receptor subfamily 0 group B member 1" P51843 X 30304206-30309390 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Receptor, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 32.7;testis: 19.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 5.4;Ionocytes: 8.2;monocytes: 2.6;Oligodendrocyte precursor cells: 10.6;Theca cells: 4.9" "Cancer enhanced" "Detected in many" "lung cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A549: 62.5;RT4: 19.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061948, HPA067207" Supported "Nuclear speckles,Vesicles,Centriolar satellite" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "Vesicles, Centriolar satellite" "HPA061948: AB_2732673, HPA067207: AB_2732761" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" "unprognostic (9.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (7.45e-3)" "unprognostic (4.83e-2)" "unprognostic (9.00e-2)" "unprognostic (1.33e-3)" 0.2 32.7 1.4 0.0 1.3 0.0 0.2 1.0 1.5 2.4 0.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 1.4 1.3 3.6 2.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.2 0.1 0.7 19.3 5.9 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 62.5 0.0 0.0 2.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 8.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.3 1.0 1.5 1.3 1.8 1.4 1.3 1.3 1.2 5.9 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.1 5.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 8.2 0.0 0.0 1.9 1.2 0.1 1.8 0.0 2.6 0.0 0.0 10.6 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.8 0.0 0.1 0.0 0.0 4.9 0.0 0.1 NR1H2 "LXR-b, LXRb, NER, NER-I, RIP15, UNR" ENSG00000131408 "Nuclear receptor subfamily 1 group H member 2" P55055 19 50329653-50383388 "Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005446, HPA056838, HPA070212" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Vesicles "HPA005446: , HPA056838: AB_2683254, HPA070212: AB_2686234" "unprognostic (1.31e-1)" "unprognostic (5.35e-2)" "prognostic unfavorable (9.86e-4)" "unprognostic (1.34e-3)" "unprognostic (1.68e-1)" "unprognostic (5.24e-3)" "unprognostic (2.26e-2)" "unprognostic (9.69e-2)" "unprognostic (6.45e-2)" "unprognostic (5.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.88e-1)" "unprognostic (2.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (5.12e-2)" "unprognostic (1.69e-3)" 59.6 61.4 43.2 37.1 45.6 143.4 57.9 43.1 53.3 61.1 41.3 78.7 43.1 67.3 10.8 56.0 63.6 28.4 89.6 40.7 45.0 63.9 61.0 66.4 33.9 55.8 47.3 56.9 49.8 32.1 40.6 26.3 48.5 63.7 11.9 9.4 46.9 37.9 132.1 60.7 55.1 20.3 44.4 56.7 60.2 31.8 48.4 21.4 56.5 36.7 16.7 77.1 58.3 47.8 56.2 124.1 12.1 32.4 34.5 36.4 42.0 75.8 53.4 38.4 41.7 25.8 48.9 34.8 67.1 39.4 31.7 46.8 7.8 34.1 9.5 89.9 57.6 32.5 41.8 26.4 63.7 58.2 84.0 34.8 45.2 39.3 27.3 37.7 33.4 24.7 51.7 65.4 20.8 53.2 39.3 40.5 25.5 32.2 94.4 22.8 35.8 57.2 30.4 54.3 14.9 50.6 50.9 54.0 46.7 6.6 37.9 42.5 53.9 54.3 45.3 58.4 66.8 82.5 79.3 26.4 108.6 36.5 53.8 159.1 123.9 232.4 90.4 125.4 89.3 112.3 89.9 86.2 121.3 117.7 90.8 81.4 194.8 85.9 146.4 103.9 89.0 129.3 43.2 45.6 43.1 53.3 40.7 45.0 55.8 47.3 48.5 44.4 48.4 47.8 50.7 28.9 30.7 3.6 70.7 43.0 89.3 53.2 32.5 37.9 33.4 27.3 29.6 37.1 31.1 31.3 14.6 64.5 57.0 82.1 64.6 63.6 15.5 31.9 19.5 50.0 20.8 58.9 5.9 72.6 53.3 40.2 37.2 33.8 50.2 25.1 36.8 20.7 51.3 37.0 5.5 45.5 46.8 37.0 48.3 9.5 45.4 54.5 60.5 4.7 65.2 46.8 65.9 0.5 6.9 74.3 89.6 53.4 47.5 91.0 93.5 61.8 21.7 25.4 39.5 45.5 50.2 34.6 25.9 27.9 45.7 140.0 54.8 27.7 35.7 109.0 NR4A2 "HZF-3, NOT, NURR1, RNR1, TINUR" ENSG00000153234 "Nuclear receptor subfamily 4 group A member 2" P43354 2 156324437-156342348 "Cancer-related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 129.3;bone marrow: 130.8;ovary: 129.2" "Cell type enhanced" "Detected in many" "B-cells: 511.7;dendritic cells: 410.4;Langerhans cells: 782.3;Macrophages: 577.5;T-cells: 465.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 16.0;HMC-1: 10.9;SK-MEL-30: 8.1;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000543, CAB010481" Uncertain Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "CAB010481: AB_2298676, HPA000543: AB_1854631" "unprognostic (4.26e-2)" "unprognostic (2.14e-1)" "unprognostic (3.42e-2)" "unprognostic (4.10e-2)" "unprognostic (3.04e-2)" "unprognostic (5.26e-2)" "unprognostic (2.30e-1)" "unprognostic (6.14e-2)" "unprognostic (8.63e-2)" "unprognostic (3.88e-2)" "unprognostic (1.60e-2)" "unprognostic (2.89e-1)" "unprognostic (2.39e-2)" "unprognostic (3.58e-2)" "unprognostic (3.43e-1)" "unprognostic (9.29e-3)" "unprognostic (1.11e-1)" 40.0 129.3 4.3 24.5 44.1 130.8 15.6 36.2 8.8 18.3 5.9 9.5 2.9 15.0 1.7 11.4 28.2 32.7 36.6 15.1 3.6 19.2 20.2 18.8 6.3 3.2 9.2 129.2 9.2 8.8 54.0 5.2 2.8 25.6 18.7 5.3 19.2 15.5 11.6 12.8 7.8 14.5 0.9 4.6 19.9 5.6 2.5 9.7 15.2 7.8 1.4 50.9 14.0 6.4 0.9 1.3 0.5 1.8 3.2 0.7 0.9 1.1 5.5 0.4 1.3 0.0 3.3 0.0 1.2 0.4 0.4 1.6 2.6 0.7 0.4 1.3 1.4 1.0 16.0 0.0 0.6 0.7 10.9 0.6 1.2 0.4 0.4 2.1 0.3 0.0 1.6 1.0 1.1 1.9 0.0 0.8 2.1 1.5 0.8 0.2 0.7 3.3 0.6 0.8 2.7 0.1 2.6 4.1 8.1 0.3 0.2 1.0 0.7 2.9 0.8 0.7 0.4 14.2 1.8 0.0 5.3 1.0 7.0 1.9 1.7 2.4 1.0 0.3 0.5 0.4 0.3 0.5 1.9 0.3 0.5 0.2 6.5 0.0 0.7 0.0 0.4 0.5 4.3 44.1 36.2 8.8 15.1 3.6 3.2 9.2 2.8 0.9 2.5 6.4 70.7 25.6 124.7 7.8 511.7 218.6 25.8 87.5 298.7 11.8 120.8 160.1 11.9 17.2 58.3 71.7 50.1 4.7 410.4 35.0 0.0 13.1 36.7 209.6 33.9 111.9 206.4 12.0 5.8 9.1 6.5 164.9 103.9 349.7 349.3 4.3 45.0 6.8 125.1 0.0 0.8 95.4 42.7 161.1 782.3 37.2 4.1 577.5 241.9 5.6 7.9 1.6 3.1 4.0 2.3 11.7 41.9 0.7 203.5 49.1 25.9 0.4 54.6 33.4 13.1 63.0 169.8 1.8 3.3 230.2 213.7 9.9 465.1 34.4 57.5 29.5 NR4A3 "CHN, CSMF, MINOR, NOR1" ENSG00000119508 "Nuclear receptor subfamily 4 group A member 3" Q92570 9 99821855-99866891 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 305.7;Langerhans cells: 417.5;Macrophages: 172.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BJ hTERT+: 24.1;HeLa: 8.0;SK-MEL-30: 18.5;U-266/70: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043360 Uncertain NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "HPA043360: AB_10961186" "prognostic favorable (5.97e-4)" "unprognostic (6.92e-3)" "unprognostic (5.34e-2)" "unprognostic (2.78e-3)" "unprognostic (1.40e-1)" "unprognostic (9.46e-2)" "unprognostic (2.89e-2)" "unprognostic (3.30e-2)" "unprognostic (2.65e-3)" "unprognostic (1.40e-2)" "unprognostic (2.28e-1)" "unprognostic (3.30e-1)" "unprognostic (2.25e-1)" "unprognostic (1.29e-3)" "unprognostic (6.11e-2)" "unprognostic (2.80e-2)" "unprognostic (1.69e-1)" 43.2 61.2 3.4 14.9 6.3 32.7 7.4 14.1 5.5 11.4 4.2 9.8 0.7 15.7 0.7 4.0 24.8 23.5 67.2 10.2 7.4 7.8 9.0 19.6 1.3 6.3 3.9 46.8 5.2 3.0 21.2 6.5 5.9 15.6 4.0 8.7 2.4 3.3 62.8 2.4 5.8 13.4 1.1 3.5 13.7 1.0 2.9 6.5 7.2 6.2 0.9 32.8 5.1 2.3 0.1 0.1 0.7 0.1 1.3 0.4 1.1 1.5 24.1 0.2 0.2 0.2 0.1 0.2 0.3 0.7 0.5 0.1 0.5 0.0 0.1 1.8 0.3 0.1 8.0 0.0 0.2 0.1 2.3 0.3 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.7 0.0 0.2 0.0 0.2 0.6 0.0 1.1 0.0 0.0 0.1 0.4 0.4 2.7 2.0 18.5 0.2 0.0 0.0 0.1 1.4 0.4 1.8 0.1 9.2 0.1 0.0 0.9 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.4 6.3 14.1 5.5 10.2 7.4 6.3 3.9 5.9 1.1 2.9 2.3 9.6 12.8 19.7 3.9 101.5 79.5 14.0 3.5 97.9 0.9 44.2 58.5 305.7 4.3 10.0 16.5 10.4 2.3 91.3 2.0 0.0 0.1 1.4 93.1 12.8 16.2 27.3 0.4 13.1 1.7 2.2 60.3 32.6 124.3 120.7 1.2 7.5 0.5 10.5 0.0 6.2 3.8 2.0 12.3 417.5 2.4 1.5 172.8 88.9 2.8 43.0 3.6 1.0 1.5 0.9 0.2 2.3 1.2 37.9 4.7 0.6 0.1 11.4 1.7 0.0 35.7 75.0 1.1 1.6 15.9 59.5 5.6 69.6 1.0 1.7 3.4 NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, CAB079912" Uncertain Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903" "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" 19.0 9.1 10.3 25.7 11.2 58.5 18.0 11.5 12.3 12.5 8.6 27.8 21.5 12.4 7.8 20.7 10.3 17.2 8.3 10.2 12.2 20.9 24.9 18.5 30.4 12.3 12.1 9.6 11.4 9.0 4.3 28.3 12.3 11.4 26.6 6.6 10.9 7.1 7.7 19.8 22.5 14.1 11.7 18.6 21.8 9.6 11.4 39.0 16.1 7.8 29.7 22.2 8.6 13.4 93.7 24.9 65.2 24.9 26.4 56.3 46.5 43.5 48.4 79.5 89.0 50.4 33.9 70.4 56.3 58.9 55.4 26.0 88.2 70.6 113.4 96.5 34.2 47.8 34.5 60.2 52.3 120.0 71.0 51.1 56.1 91.5 66.2 25.0 102.8 54.6 77.3 78.5 71.0 248.9 83.5 46.4 111.0 30.2 17.9 62.9 116.0 44.1 70.6 49.5 39.4 59.0 44.7 36.4 107.1 75.4 31.9 96.2 79.2 43.3 82.2 81.5 90.3 137.7 101.6 81.6 86.4 64.6 159.0 38.7 12.8 12.6 11.7 19.2 10.5 12.8 9.3 11.6 12.6 10.5 9.9 12.9 3.4 15.5 17.6 9.6 13.4 13.1 10.3 11.2 11.5 12.3 10.2 12.2 12.3 12.1 12.3 11.7 11.4 13.4 22.7 16.0 16.5 8.1 25.9 30.7 31.2 23.1 15.4 5.2 18.5 13.6 5.6 18.6 19.3 22.0 8.4 22.4 27.7 49.2 13.7 34.1 3.9 22.9 24.7 29.2 24.6 31.6 5.8 31.5 50.4 16.1 29.0 38.0 31.1 22.2 33.2 29.7 49.2 5.0 5.2 28.1 30.5 44.9 30.7 5.9 8.1 30.4 23.2 9.4 41.6 7.8 22.6 5.0 8.1 51.4 32.9 6.4 39.6 30.6 28.1 39.4 23.1 3.3 6.6 12.8 15.3 7.3 15.4 24.6 36.2 31.2 21.9 13.8 28.8 40.2 NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 17 "Excitatory neurons: 1466.4;Inhibitory neurons: 411.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Cell line enhanced" "Detected in many" "A549: 132.5;BJ: 91.3;fHDF/TERT166: 98.1;GAMG: 95.4;U-2197: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" 0.5 1.2 3.5 6.1 3.2 1.4 5.7 8.7 13.2 8.0 3.2 3.2 2.9 1.2 0.6 2.8 1.1 2.3 1.9 0.4 12.7 8.6 17.0 3.7 0.4 35.4 8.0 1.9 0.7 0.6 3.8 0.2 35.3 2.6 3.2 11.6 2.6 1.0 0.1 4.9 2.5 1.0 2.7 1.6 2.5 5.3 2.6 0.8 9.9 0.0 2.1 9.4 3.4 8.2 0.4 132.5 1.8 0.0 0.9 2.5 0.2 91.3 60.0 65.3 55.8 0.0 2.9 0.0 16.4 98.1 95.4 76.7 0.3 34.5 69.4 0.2 0.7 1.3 1.8 2.0 0.4 0.1 0.2 1.3 3.4 81.1 74.6 5.7 41.2 0.1 0.0 0.7 24.4 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.9 0.0 52.9 3.6 3.4 4.0 7.5 0.0 0.1 5.0 0.0 0.3 34.7 50.7 15.8 84.4 53.6 0.1 0.0 0.9 28.2 0.1 6.6 0.2 55.3 0.9 0.2 4.7 0.2 0.1 0.1 0.0 12.1 0.1 0.0 0.0 2.0 0.2 0.2 0.2 0.0 14.2 3.5 3.2 8.7 13.2 0.4 12.7 35.4 8.0 35.3 2.7 2.6 8.2 0.1 38.5 2.7 29.7 0.8 26.0 48.0 5.1 21.1 11.0 4.3 18.2 2.0 8.6 7.9 3.7 8.4 0.0 1.3 0.0 9.8 1.8 41.5 0.1 1.9 5.7 0.0 0.0 1466.4 0.2 0.0 10.5 0.0 0.2 1.3 3.2 7.1 5.3 0.5 28.6 411.8 0.0 2.0 10.2 1.9 23.5 0.3 22.1 1.8 36.5 49.2 5.0 0.0 54.3 19.2 0.9 0.0 0.4 0.0 42.9 0.0 18.7 2.4 3.1 0.0 0.1 9.3 11.3 5.0 3.2 6.1 0.0 0.6 0.0 0.0 6.5 NRG2 "Don-1, HRG2, NTAK" ENSG00000158458 "Neuregulin 2" O14511 5 139846779-140043299 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.5;Excitatory neurons: 89.9;Inhibitory neurons: 136.6;Oligodendrocyte precursor cells: 142.2;Oligodendrocytes: 50.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;HDLM-2: 4.0;Karpas-707: 4.4;PC-3: 11.1;RPTEC TERT1: 5.8;SCLC-21H: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038935, HPA047973" Approved Supported Nucleoplasm,Nucleoli "Secreted in other tissues" No NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Nucleoli "HPA038935: AB_10672833, HPA047973: AB_2680226" "unprognostic (8.66e-4)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (6.04e-2)" "unprognostic (3.22e-1)" "unprognostic (2.96e-2)" "unprognostic (8.66e-3)" "unprognostic (1.11e-1)" "unprognostic (3.99e-1)" "unprognostic (1.88e-1)" "unprognostic (4.26e-3)" "unprognostic (4.00e-2)" "unprognostic (7.79e-3)" "unprognostic (3.64e-3)" "unprognostic (9.54e-2)" "unprognostic (2.23e-2)" "unprognostic (2.07e-2)" 2.3 3.4 2.9 0.5 2.8 0.0 3.3 8.5 3.1 5.8 0.0 2.1 0.2 1.2 1.1 1.6 3.3 1.2 1.2 2.0 2.4 0.8 0.1 0.4 0.8 3.2 2.6 7.5 2.7 8.1 3.5 0.3 3.0 3.1 0.1 1.3 6.5 1.9 5.0 3.6 0.7 0.3 1.5 1.7 0.8 2.1 2.6 0.5 0.7 0.1 0.4 3.1 1.8 2.3 0.0 1.6 0.1 6.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.3 0.0 2.8 2.1 0.3 0.1 0.1 4.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.1 0.1 0.0 4.4 0.0 0.2 0.0 0.0 0.1 0.0 11.1 0.1 0.0 0.0 5.8 1.5 4.2 2.5 0.0 2.7 2.6 0.0 0.0 0.0 0.1 1.9 0.3 0.0 1.3 0.8 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.8 8.5 3.1 2.0 2.4 3.2 2.6 3.0 1.5 2.6 2.3 15.9 0.0 0.0 71.5 1.6 2.8 9.7 0.9 29.0 16.6 4.0 16.0 2.2 0.0 0.5 1.8 0.0 0.1 3.2 0.1 1.9 0.4 0.6 2.6 8.2 2.6 0.0 0.0 89.9 2.2 0.0 2.7 0.5 0.4 0.0 1.3 1.8 0.0 0.1 6.7 136.6 0.1 0.0 0.3 1.3 0.6 9.6 0.6 3.6 8.4 0.3 11.2 5.2 142.2 50.8 0.5 0.0 10.1 2.7 2.6 0.0 1.7 1.0 1.0 6.6 10.9 2.2 2.7 9.4 1.0 0.3 0.0 2.8 4.0 0.1 6.2 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 366.0;Endothelial cells: 174.4;Hepatic stellate cells: 184.6;Sertoli cells: 282.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 444.6;hTERT-RPE1: 371.6;TIME: 369.5;U-87 MG: 425.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" 125.2 42.3 9.3 43.3 9.4 3.7 62.2 0.0 26.0 36.9 13.3 26.6 21.3 51.6 35.7 19.7 34.5 54.1 80.8 48.6 9.1 52.7 53.1 63.7 23.7 4.0 3.9 43.0 33.0 24.4 9.0 133.7 2.1 21.3 23.6 11.6 19.3 38.4 55.9 22.1 21.0 55.9 5.7 66.7 18.6 12.9 13.4 18.2 49.7 46.6 12.4 35.3 20.0 10.7 57.4 217.8 11.1 1.1 204.8 224.7 1.3 224.4 216.2 109.6 118.2 28.9 132.4 1.1 26.6 444.6 116.8 15.8 13.8 65.2 89.3 0.7 11.2 0.6 24.5 48.7 74.3 20.8 1.6 277.3 11.2 261.7 116.8 371.6 304.0 1.4 0.7 1.4 221.3 96.8 1.4 3.9 5.5 11.9 204.2 9.6 24.8 1.2 109.7 1.3 5.1 2.7 23.0 17.5 0.9 9.2 1.0 3.3 369.5 156.4 36.9 193.0 153.8 0.7 1.1 0.7 425.2 26.4 143.5 0.4 2.5 0.5 0.6 0.4 1.0 0.7 0.7 0.6 2.3 0.6 0.6 0.6 0.4 1.2 0.3 39.3 0.6 0.9 9.3 9.4 0.0 26.0 48.6 9.1 4.0 3.9 2.1 5.7 13.4 10.7 366.0 0.0 20.2 80.3 4.3 15.7 10.6 5.5 7.4 10.5 4.2 5.5 67.6 28.6 13.0 18.4 4.2 61.5 29.4 0.6 1.9 57.9 1.3 11.3 116.9 174.4 4.2 3.2 105.4 18.9 13.4 58.5 6.6 11.0 7.6 62.3 184.6 12.5 135.4 0.0 14.4 1.8 16.2 62.7 33.3 5.5 42.3 46.0 12.4 78.7 5.8 3.4 0.0 11.6 2.3 15.4 0.0 21.1 1.6 4.1 3.0 59.8 5.4 0.9 282.7 13.1 117.9 0.2 1.3 2.7 10.5 67.2 3.8 61.1 1.5 3.3 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 8.7 7.2 8.9 12.0 13.4 21.2 10.9 26.2 10.4 11.1 9.8 10.1 8.4 11.5 10.3 11.4 10.1 8.0 9.1 7.7 10.0 10.6 6.6 9.2 13.7 9.7 10.8 12.3 11.3 12.8 9.0 10.7 12.2 9.3 10.8 11.9 10.4 9.6 13.6 12.0 9.4 12.0 6.6 11.3 8.9 23.2 12.0 20.2 15.5 11.5 14.7 9.3 7.9 17.5 20.5 25.9 26.0 22.8 12.5 16.1 0.9 18.2 17.9 24.6 22.8 5.7 16.6 41.7 19.9 24.8 22.7 17.0 41.9 40.0 29.7 72.9 25.9 18.6 29.5 0.2 20.7 40.4 21.2 15.2 23.6 29.4 27.3 17.5 36.4 26.0 25.9 14.3 25.2 42.3 28.3 13.1 28.5 13.7 22.5 31.0 3.4 12.9 15.9 24.4 31.6 21.9 46.7 20.1 13.8 24.1 20.2 33.0 27.4 17.1 25.0 11.0 22.6 16.7 15.7 29.5 9.9 19.3 18.7 14.7 9.0 10.5 7.2 6.1 6.0 8.5 6.1 5.0 7.2 10.3 7.5 6.0 18.6 11.3 12.2 9.4 6.4 3.4 8.9 13.4 26.2 10.4 7.7 10.0 9.7 10.8 12.2 6.6 12.0 17.5 37.4 22.4 31.4 84.9 71.7 17.0 32.8 27.2 34.1 94.4 29.8 25.7 44.5 34.3 35.0 55.2 150.1 43.6 66.1 19.7 17.6 27.8 31.9 27.1 65.7 36.4 41.9 48.3 107.0 21.2 23.7 32.7 41.8 41.9 41.7 64.0 33.5 19.9 27.7 89.2 110.3 25.6 12.2 36.8 25.7 50.3 51.0 47.1 16.0 115.2 75.0 29.2 95.8 140.8 157.5 23.7 31.0 33.1 55.8 29.4 33.6 19.2 17.3 112.3 52.6 42.9 36.1 83.7 62.1 41.8 20.6 35.4 62.0 55.9 28.2 30.0 NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871393-1982207 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 20.3;Granulosa cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm No No "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "CAB068246: AB_2665690, CAB068247: AB_2665689, HPA015801: AB_1858830" "unprognostic (3.70e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-2)" "unprognostic (1.77e-1)" "unprognostic (4.01e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.24e-2)" "unprognostic (6.22e-2)" "unprognostic (7.66e-2)" "unprognostic (2.09e-1)" "unprognostic (9.25e-3)" "prognostic unfavorable (7.19e-4)" "unprognostic (3.89e-2)" "unprognostic (2.95e-1)" "unprognostic (1.31e-1)" "unprognostic (6.15e-2)" 10.1 8.4 12.7 16.5 13.0 54.9 9.9 23.6 15.2 9.4 0.8 19.6 18.6 10.7 7.3 13.6 8.4 8.3 15.8 11.8 11.5 9.8 8.3 12.6 25.4 9.8 8.6 7.7 13.5 12.0 13.8 12.2 12.0 9.7 22.5 28.5 11.6 8.4 16.7 11.6 18.3 12.4 4.4 14.1 12.5 37.2 12.6 59.8 17.4 13.7 24.3 9.7 9.2 14.9 124.0 58.6 168.3 71.2 17.5 26.5 44.2 98.2 85.4 115.2 128.8 44.6 141.4 117.5 31.4 78.0 158.5 50.2 114.4 74.3 195.0 58.3 47.7 151.3 81.7 25.5 18.6 89.5 74.9 9.9 19.8 101.2 89.9 60.1 92.2 123.4 81.7 132.2 95.8 42.1 243.3 99.7 68.8 60.1 77.1 137.8 106.7 42.9 45.4 57.4 115.6 82.7 78.4 29.2 31.7 71.4 68.9 52.2 64.9 109.0 87.4 72.8 188.1 54.1 72.9 113.7 66.0 81.9 108.0 4.0 1.1 1.3 1.0 0.8 1.1 0.9 1.5 1.2 1.2 1.7 1.1 0.8 3.4 1.2 0.5 2.1 2.9 0.7 12.7 13.0 23.6 15.2 11.8 11.5 9.8 8.6 12.0 4.4 12.6 14.9 12.6 12.8 18.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 15.3 9.1 0.0 0.0 8.1 12.9 0.0 15.7 7.2 0.0 3.9 10.4 0.0 13.0 11.7 6.3 0.0 0.0 0.0 7.1 10.0 6.0 0.0 20.3 2.5 69.3 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 5.7 0.0 0.0 0.0 0.0 11.4 0.0 0.0 4.9 0.0 0.0 4.0 7.3 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 3.4 5.2 3.7 0.0 0.0 NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269704-38382272 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 173.8;Syncytiotrophoblasts: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005659, CAB013721, HPA018893" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "CAB013721: , HPA005659: AB_1080596, HPA018893: AB_1858833" "unprognostic (6.21e-2)" "unprognostic (3.73e-2)" "unprognostic (2.18e-2)" "unprognostic (4.12e-1)" "unprognostic (2.25e-1)" "unprognostic (1.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.60e-2)" 22.4 14.4 10.0 24.8 13.7 60.2 23.4 28.4 20.5 24.0 0.7 22.4 24.1 22.9 17.4 22.9 23.5 24.5 13.7 12.8 22.3 20.0 16.6 20.6 35.3 3.1 4.8 36.4 20.1 24.8 17.3 33.5 5.3 20.9 26.6 23.3 19.9 24.3 14.4 19.8 26.7 19.8 0.1 26.9 29.0 14.4 10.4 38.3 27.6 16.0 31.0 23.3 23.1 18.7 62.1 34.9 58.7 39.9 40.3 46.0 43.4 50.8 55.9 43.1 49.7 18.8 33.6 73.5 45.5 35.0 41.7 36.4 47.0 40.6 61.0 29.4 27.6 93.6 28.6 22.1 41.2 41.7 32.5 24.9 40.4 39.0 78.6 40.3 50.1 79.8 67.9 47.4 41.5 22.3 122.8 35.4 40.0 48.0 16.4 55.5 64.1 23.4 30.3 47.3 33.0 44.6 41.4 35.8 35.3 37.5 45.1 31.4 48.3 44.5 46.0 67.0 30.3 41.9 53.8 69.2 37.6 41.3 33.0 37.4 11.8 21.9 17.2 5.6 11.0 43.1 25.5 15.5 9.3 60.7 31.9 13.7 57.9 19.6 3.6 12.6 43.4 7.3 10.0 13.7 28.4 20.5 12.8 22.3 3.1 4.8 5.3 0.1 10.4 18.7 75.1 67.3 57.3 0.0 57.8 0.0 0.0 0.0 0.0 0.0 73.4 69.1 0.0 0.0 30.3 51.5 0.0 101.6 101.9 0.0 23.5 73.0 0.0 109.1 81.3 28.0 0.0 0.0 0.0 61.0 173.8 33.1 0.0 97.5 8.8 99.7 0.0 0.0 44.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 49.7 0.0 0.0 0.0 0.0 64.7 0.0 0.0 48.9 0.0 0.0 31.7 34.2 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 130.8 55.6 81.7 0.0 0.0 NT5C2 "cN-II, GMP, NT5B, PNT5, SPG45, SPG65" ENSG00000076685 "5'-nucleotidase, cytosolic II" P49902 10 103087185-103277605 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Allosteric enzyme, Hydrolase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 141.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003751 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA003751: AB_1854664" "unprognostic (8.18e-2)" "unprognostic (1.98e-1)" "unprognostic (2.55e-2)" "unprognostic (2.46e-1)" "unprognostic (5.54e-2)" "unprognostic (4.87e-3)" "unprognostic (2.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.41e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-3)" "unprognostic (6.20e-2)" "unprognostic (3.26e-2)" "unprognostic (3.70e-2)" "unprognostic (6.40e-2)" "unprognostic (3.43e-1)" "unprognostic (1.50e-1)" 24.6 27.0 25.0 19.0 27.2 29.7 23.0 27.3 28.5 37.6 36.8 27.3 9.9 18.8 17.3 67.1 26.5 16.4 28.5 25.2 28.8 32.5 27.8 30.8 18.3 26.9 29.5 32.4 22.0 21.7 34.0 17.9 27.2 32.4 16.7 47.3 46.4 18.4 51.6 19.9 20.4 13.4 26.4 32.8 22.3 30.8 27.2 28.6 55.4 18.1 24.5 33.3 42.7 28.6 148.4 52.5 32.6 67.5 27.2 33.2 18.2 66.0 64.7 29.9 32.4 34.6 91.7 49.2 47.7 45.6 27.6 62.8 23.4 33.8 38.3 40.3 21.6 38.7 21.1 39.6 48.5 64.2 21.0 50.4 34.1 28.0 24.8 57.5 25.6 19.4 29.4 36.4 54.5 73.8 53.7 64.6 34.6 43.2 68.6 102.6 30.0 19.6 43.3 72.5 10.0 24.9 35.8 25.9 50.3 33.7 39.2 38.1 30.5 20.5 24.8 39.7 51.7 32.9 71.6 85.5 23.9 64.6 7.8 29.5 16.5 31.3 10.0 18.8 10.3 8.9 8.4 8.7 14.7 5.2 6.7 8.0 27.4 14.4 23.0 9.6 9.3 10.5 25.0 27.2 27.3 28.5 25.2 28.8 26.9 29.5 27.2 26.4 27.2 28.6 16.2 83.3 34.9 141.7 17.2 7.4 29.0 26.9 5.7 24.4 13.9 13.6 2.6 18.6 60.4 27.6 45.9 19.4 23.3 48.7 11.7 28.5 103.7 29.5 17.1 19.8 11.5 12.4 79.8 26.0 11.7 17.5 25.5 46.2 8.8 18.2 13.9 17.4 19.9 47.1 83.6 17.6 18.3 29.8 14.2 61.9 24.8 27.1 26.6 78.7 25.9 85.5 16.5 70.4 107.5 57.9 23.1 13.5 21.0 35.7 11.7 15.3 44.1 59.1 32.9 22.9 21.7 25.3 20.5 22.9 7.5 35.0 16.6 15.8 18.0 80.5 NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.5;Basal prostatic cells: 36.6;Basal squamous epithelial cells: 89.4;Prostatic glandular cells: 20.5;Sertoli cells: 32.9;Smooth muscle cells: 24.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in some" 5 "cerebellum: 3.4;cerebral cortex: 1.3;hippocampal formation: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.4;BJ hTERT+ SV40 Large T+: 14.8;BJ hTERT+ SV40 Large T+ RasG12V: 19.7;HBF TERT88: 18.0;RT4: 8.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 4.7;cerebral cortex: 2.0;hippocampal formation: 2.2" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA032001: AB_2674106" "unprognostic (3.04e-2)" "unprognostic (7.46e-2)" "unprognostic (7.33e-3)" "unprognostic (4.66e-3)" "unprognostic (8.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-3)" "unprognostic (7.68e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (2.20e-1)" "unprognostic (7.77e-4)" "unprognostic (4.02e-3)" "unprognostic (1.92e-1)" "unprognostic (8.06e-3)" "unprognostic (4.51e-3)" 4.2 1.8 0.2 0.7 0.4 0.0 2.7 3.4 1.3 6.6 0.2 1.8 1.9 1.9 2.0 3.4 2.9 1.8 3.1 1.2 0.3 2.6 7.7 1.6 0.3 0.4 0.2 11.1 0.2 0.1 1.0 1.9 0.3 3.6 1.0 0.1 3.1 2.4 1.8 3.2 2.5 0.9 0.3 4.5 2.5 0.8 0.1 0.4 0.9 1.0 0.4 4.6 7.0 0.2 1.9 0.0 6.7 0.0 0.0 0.0 0.0 4.5 11.4 14.8 19.7 0.1 0.2 0.0 6.7 7.3 0.0 2.4 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 4.5 4.7 8.5 0.3 0.0 0.0 0.1 0.0 3.9 0.0 0.0 0.0 0.0 3.1 0.2 0.0 0.2 0.1 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 3.4 1.3 1.2 0.3 0.4 0.2 0.3 0.3 0.1 0.2 1.0 0.0 0.0 0.0 0.0 18.5 36.6 0.7 89.4 0.0 0.2 10.3 0.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.2 1.4 0.0 0.0 0.1 0.0 0.1 6.1 0.0 0.1 0.0 0.0 5.0 2.1 0.0 0.0 1.2 0.1 0.0 0.0 2.1 0.1 8.4 0.3 7.2 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 10.9 0.0 20.5 0.2 0.0 0.8 0.0 32.9 6.8 24.0 0.5 0.8 5.0 3.3 0.1 0.5 0.5 0.2 6.9 NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065054 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 20.1;skeletal muscle: 17.1;skin 1: 31.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 35.6;Basal respiratory cells: 24.0;Basal squamous epithelial cells: 15.4;Breast myoepithelial cells: 24.3;Club cells: 9.5;Cytotrophoblasts: 13.6;Urothelial cells: 11.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 31.1;HBEC3-KT: 11.7;hTCEpi: 50.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA049376: AB_2680735" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" "unprognostic (9.27e-4)" "unprognostic (1.76e-4)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.87e-3)" "unprognostic (3.90e-4)" "unprognostic (2.97e-1)" "unprognostic (1.40e-3)" "unprognostic (3.71e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-2)" "unprognostic (2.46e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 4.3 0.7 0.0 0.0 0.1 3.7 10.8 2.5 0.0 1.0 0.1 0.0 0.1 0.0 3.5 0.0 0.1 0.2 0.2 0.0 0.0 1.6 3.2 0.1 20.1 0.0 0.0 8.2 7.1 17.1 31.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.9 1.5 2.5 1.1 6.5 9.6 0.1 3.9 0.2 0.3 2.1 0.0 0.0 9.3 0.0 0.0 0.1 0.0 3.4 13.8 0.0 3.5 0.0 0.5 31.1 0.1 11.7 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 50.4 0.0 1.6 3.1 0.0 0.1 0.0 0.2 0.4 1.2 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 8.8 0.0 0.1 0.7 0.1 0.0 4.3 8.0 0.1 0.2 1.8 3.5 0.2 9.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 3.2 0.0 0.0 0.0 7.0 35.6 24.0 15.4 0.0 3.4 24.3 0.4 0.0 9.5 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 5.7 0.0 0.0 0.0 0.9 0.0 1.3 1.7 3.1 2.7 0.3 0.1 0.0 11.9 NTHL1 "NTH1, OCTS3" ENSG00000065057 "Nth like DNA glycosylase 1" P78549 16 2039815-2047866 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 10 "Hepatocytes: 866.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025152 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "CAB025152: " "unprognostic (1.06e-1)" "unprognostic (9.71e-2)" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (7.89e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-1)" "unprognostic (2.46e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "unprognostic (2.77e-2)" "unprognostic (6.78e-2)" "unprognostic (6.53e-2)" "unprognostic (2.27e-1)" "unprognostic (1.34e-1)" "unprognostic (5.08e-2)" "unprognostic (1.62e-2)" 11.7 9.3 13.8 6.2 14.7 4.7 11.0 14.8 19.7 15.5 11.1 16.8 6.6 15.4 3.1 11.3 13.8 6.0 15.8 13.5 14.2 9.8 21.9 10.7 8.4 15.4 13.9 16.1 9.9 4.8 11.5 5.6 15.6 11.2 5.6 1.8 16.0 11.5 9.7 9.3 11.1 5.3 13.6 16.7 13.2 8.7 15.2 7.6 9.6 6.8 5.9 11.8 12.5 14.2 29.8 74.2 20.8 32.2 8.5 15.9 22.8 12.1 13.2 23.1 14.6 53.0 28.8 63.0 25.2 10.7 15.1 26.2 26.1 29.0 4.0 28.9 63.3 19.5 47.7 60.9 11.5 22.4 22.3 13.2 14.9 12.3 13.2 15.4 33.4 37.0 22.2 22.6 9.0 34.9 33.9 88.3 46.2 37.3 47.3 80.8 22.0 103.5 17.2 10.7 43.9 43.5 13.2 41.0 25.4 7.6 29.6 23.5 12.9 19.9 21.5 17.5 23.1 30.3 38.0 26.9 8.8 31.7 24.9 4.2 15.0 3.4 14.4 26.0 16.2 37.5 17.3 16.7 25.7 32.8 12.8 15.4 0.7 19.1 22.5 26.3 34.0 14.4 13.8 14.7 14.8 19.7 13.5 14.2 15.4 13.9 15.6 13.6 15.2 14.2 47.2 28.9 27.5 2.9 12.9 8.7 16.4 21.6 8.0 8.8 18.9 23.4 14.1 44.3 28.3 3.7 0.0 10.5 8.1 75.6 17.6 16.3 8.1 20.4 19.5 36.5 67.4 26.7 3.0 9.1 18.3 17.6 16.3 23.3 5.7 20.5 51.0 866.4 13.4 6.7 3.6 85.3 54.9 25.5 17.6 23.8 33.8 9.3 21.4 2.8 9.7 10.7 18.6 3.0 4.9 12.1 81.6 25.2 16.0 6.4 12.8 28.8 23.5 8.1 13.1 8.1 23.6 5.4 32.0 11.7 10.1 2.7 12.2 20.6 56.8 21.0 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 181.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 198.6;Hepatic stellate cells: 369.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 513.8;hTERT-HME1: 205.8;PC-3: 189.6;TIME: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA049832 Approved "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA049832: AB_2680905" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (2.85e-1)" "prognostic favorable (8.12e-9)" "unprognostic (3.52e-2)" "unprognostic (7.08e-2)" "unprognostic (1.93e-1)" "prognostic favorable (6.67e-5)" 24.4 17.3 6.4 5.7 7.5 0.1 72.9 4.4 10.5 26.5 12.0 16.5 12.0 12.7 15.3 15.6 34.4 22.4 66.8 8.9 5.7 107.6 26.7 70.2 2.9 5.9 8.7 86.1 62.5 13.3 7.6 11.9 5.7 42.4 18.1 0.6 32.6 59.1 12.6 8.8 17.5 15.0 6.1 181.5 48.7 12.1 6.2 6.2 14.4 19.9 6.5 49.5 14.4 8.7 26.7 71.3 2.0 0.1 28.5 45.0 3.0 49.7 513.8 67.1 78.2 56.1 48.8 0.0 3.5 105.3 88.1 42.2 0.6 15.3 34.0 0.0 4.3 2.3 12.7 11.1 1.7 0.0 0.1 1.1 43.5 75.0 205.8 72.9 133.3 0.4 0.0 0.1 25.4 20.0 0.2 0.3 1.1 7.9 189.6 0.2 0.6 0.1 64.8 133.4 0.3 0.6 60.5 77.1 1.3 2.3 22.2 0.1 289.3 25.9 9.5 101.3 5.2 0.1 0.1 0.0 5.9 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 7.5 4.4 10.5 8.9 5.7 5.9 8.7 5.7 6.1 6.2 8.7 31.9 41.7 123.2 6.2 3.8 4.7 120.5 15.2 39.3 1.8 77.6 55.4 44.8 44.3 30.8 198.6 0.0 6.2 1.3 4.4 5.9 36.7 10.3 36.4 3.2 35.5 0.0 2.7 28.1 28.0 3.6 33.7 23.0 28.1 1.3 25.9 369.5 10.2 0.4 0.0 70.6 37.2 4.1 26.3 3.7 3.8 2.1 2.6 7.2 20.6 0.6 0.3 0.0 112.6 1.8 36.7 4.0 3.4 0.9 108.9 1.5 84.3 38.0 0.2 26.3 119.0 73.9 1.9 0.6 5.9 2.3 1.6 3.3 1.4 6.4 127.0 NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 7.0;brain: 21.7" "Group enriched" "Detected in some" 10 "Bipolar cells: 22.8;granulocytes: 55.9;Horizontal cells: 57.2" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Group enriched" "Detected in many" 6 "cerebral cortex: 7.6;medulla oblongata: 19.8;pons: 21.7" "Immune cell enriched" "Detected in single" 116 "basophil: 94.5" "Lineage enriched" "Detected in single" 768 "granulocytes: 94.5" "Cell line enriched" "Detected in some" 4 "HMC-1: 82.1" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 4.1" "CAB004606, HPA035799, HPA076570" Approved Approved Vesicles,Cytosol NA NA 79000 "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Cytosol" "CAB004606: AB_628397, HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" 0.8 7.0 0.7 0.4 1.8 0.7 0.2 1.8 7.6 0.7 0.7 0.8 0.5 1.0 0.0 0.1 0.5 0.4 1.0 0.3 2.8 3.0 0.0 0.5 0.1 19.8 1.5 0.1 0.2 0.0 0.7 0.2 21.7 1.4 0.0 1.9 0.5 0.3 0.4 0.1 0.3 0.6 0.2 0.1 0.5 1.6 0.4 0.3 0.2 0.2 0.0 0.3 0.5 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 11.9 0.0 14.0 0.0 0.0 0.0 0.0 82.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.4 1.6 0.0 0.2 0.0 2.4 0.2 0.0 1.5 2.5 0.0 0.2 0.0 0.5 1.5 18.2 0.0 0.1 0.0 0.3 0.0 0.1 0.3 0.0 1.1 0.0 0.0 3.5 0.6 0.0 0.0 0.0 0.1 94.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.7 1.8 1.8 7.6 0.3 2.8 19.8 1.5 21.7 0.2 0.4 0.6 0.1 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 4.2 0.7 0.0 0.0 4.3 0.0 0.1 55.9 0.0 0.0 0.0 0.1 57.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.9 3.2 2.7 0.0 0.1 0.0 1.0 0.1 0.0 0.0 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027054 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 230.0;thyroid gland: 116.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1144.3;Excitatory neurons: 750.1;Inhibitory neurons: 877.7;Oligodendrocyte precursor cells: 557.9" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;HaCaT: 3.0;RPTEC TERT1: 9.7;SH-SY5Y: 11.2;SuSa: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Plasma membrane" NA NA 20000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 40.5 2.7 201.9 1.7 177.8 0.1 62.2 133.3 190.6 9.8 69.8 5.9 0.4 3.9 3.9 8.2 5.6 33.3 15.2 173.3 230.0 20.4 1.8 10.0 3.1 119.4 218.9 9.7 34.3 2.5 10.1 1.8 151.7 4.7 3.6 41.2 14.4 19.1 2.9 11.6 1.6 3.3 116.6 10.9 1.9 2.4 222.1 4.0 116.9 13.8 4.3 4.9 12.0 117.7 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 9.7 0.7 0.7 11.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 201.9 177.8 133.3 190.6 173.3 230.0 119.4 218.9 151.7 116.6 222.1 117.7 17.4 0.0 0.5 1144.3 0.7 56.6 1.0 1.8 93.9 30.3 144.1 116.8 11.4 0.0 0.2 9.2 6.2 0.0 1.0 8.7 27.4 36.1 1.8 1.2 0.4 8.0 0.0 0.0 750.1 0.7 0.1 76.6 0.0 2.3 0.0 0.1 5.0 0.0 0.2 242.3 877.7 0.7 0.0 0.0 14.2 3.6 104.1 1.4 17.8 65.6 0.6 241.0 0.0 557.9 109.5 0.5 7.0 48.2 0.3 0.9 0.0 7.1 1.7 12.2 124.9 9.9 114.4 0.8 2.3 5.2 24.6 0.0 3.3 0.2 7.2 0.9 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8" "Cell type enhanced" "Detected in many" "Astrocytes: 239.3;Early spermatids: 119.6;Excitatory neurons: 360.0;Inhibitory neurons: 277.8;Late spermatids: 148.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 499.6" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "U-138 MG: 100.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 19000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: AB_632555, HPA027484: AB_2672297, HPA048065: AB_2680245" "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 12.8 3.7 31.3 0.8 33.2 0.1 7.8 30.7 34.3 12.8 0.0 3.4 0.5 10.4 3.2 1.3 15.0 1.6 5.8 38.8 25.8 5.1 1.0 5.3 1.2 21.5 19.6 7.2 1.0 0.1 12.2 1.0 22.1 9.0 2.0 5.2 6.8 4.3 1.8 4.8 2.2 3.7 10.9 2.5 3.2 9.8 33.4 1.2 3.0 1.9 2.0 8.7 7.4 21.5 0.0 13.1 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 2.5 0.0 0.0 0.0 2.6 0.1 0.1 0.1 0.7 0.1 0.0 0.0 0.0 0.9 0.1 0.1 0.0 100.6 1.8 0.0 1.3 0.0 0.0 0.0 3.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.3 33.2 30.7 34.3 38.8 25.8 21.5 19.6 22.1 10.9 33.4 21.5 0.5 0.0 0.0 239.3 0.0 0.5 6.4 0.0 0.0 53.8 3.7 6.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 119.6 0.4 25.0 1.2 0.0 0.0 360.0 0.0 0.0 5.7 0.0 0.5 0.0 0.0 2.2 0.0 1.0 1.7 277.8 0.0 0.0 0.0 0.6 148.9 3.4 0.6 0.0 177.1 0.0 8.6 0.0 499.6 7.4 0.0 0.0 27.4 0.0 1.3 0.0 0.1 0.0 3.7 52.6 20.3 40.9 11.0 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.7 NUCB2 NEFA ENSG00000070081 "Nucleobindin 2" P80303 11 17208153-17349980 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 758.3;salivary gland: 771.4" "Cell type enhanced" "Detected in all" "Early spermatids: 690.6;Late spermatids: 508.5;Respiratory ciliated cells: 618.8;Syncytiotrophoblasts: 1158.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 1867.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008395, CAB015931, CAB079781" Enhanced Supported Enhanced "Golgi apparatus" "Secreted to blood" NA NA 1250000 690000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus" "CAB015931: , CAB079781: AB_2313672, HPA008395: AB_1854683" "unprognostic (2.49e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.27e-6)" "unprognostic (5.24e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-3)" "unprognostic (3.66e-3)" "unprognostic (1.81e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.46e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" 56.2 75.7 23.9 62.1 27.8 619.9 141.1 28.8 32.1 137.2 58.0 68.3 57.3 60.8 458.2 146.3 107.2 60.8 95.7 22.8 34.7 43.2 102.2 49.8 60.2 25.7 28.2 56.0 758.3 479.1 113.0 90.9 26.8 70.9 68.4 64.5 771.4 190.9 38.5 21.1 40.7 78.5 26.2 42.2 92.9 119.2 28.4 334.2 153.9 30.4 78.5 61.8 44.9 26.6 119.9 49.0 53.7 163.4 118.9 162.3 65.0 260.5 381.0 115.1 203.0 48.7 26.8 182.9 63.5 250.7 107.1 50.1 34.4 66.8 178.7 126.7 76.3 135.8 57.8 85.2 340.5 1867.0 238.6 71.1 86.8 82.9 200.9 284.9 143.3 672.1 120.1 361.1 114.9 105.9 656.2 670.3 12.9 194.0 50.5 239.8 130.4 15.1 51.9 37.5 63.5 35.4 114.6 114.2 61.4 78.0 93.5 498.1 128.1 120.9 110.9 369.1 112.1 70.3 41.3 101.1 140.5 646.1 106.4 210.5 43.5 168.2 94.1 30.5 122.9 22.7 88.5 173.7 40.6 14.5 246.7 271.2 39.3 277.9 25.6 426.0 42.7 119.8 23.9 27.8 28.8 32.1 22.8 34.7 25.7 28.2 26.8 26.2 28.4 26.6 118.7 44.8 70.4 16.3 54.8 27.5 60.2 156.3 14.8 71.0 152.8 87.0 193.8 55.8 176.5 42.3 54.2 127.1 136.5 17.6 27.4 91.1 690.6 112.4 92.9 94.7 42.4 137.8 21.9 132.6 319.1 148.8 40.2 97.0 67.6 80.0 108.5 141.8 70.7 35.3 23.5 189.0 189.2 29.4 40.0 508.5 149.8 37.6 69.4 18.7 24.1 111.2 95.8 13.6 10.8 75.2 13.2 114.3 256.5 108.7 3.9 28.5 618.8 99.3 46.0 50.8 75.4 174.9 61.3 87.7 30.1 1158.2 92.3 88.3 45.3 61.2 NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242226-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.6" "Cell type enhanced" "Detected in many" "Late spermatids: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012636 Approved Supported Cytosol No No 21000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA012636: AB_1854696" "unprognostic (1.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (3.01e-3)" "unprognostic (3.37e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.15e-2)" "unprognostic (4.77e-1)" "unprognostic (3.81e-2)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.29e-1)" "unprognostic (6.71e-2)" "unprognostic (3.49e-2)" "unprognostic (1.70e-1)" 19.1 8.0 13.7 23.8 16.6 77.6 15.0 14.6 18.0 16.9 10.9 19.1 16.2 12.4 5.4 29.1 12.0 10.5 18.7 15.4 13.6 8.9 6.3 12.4 37.1 16.1 14.1 9.3 9.1 3.2 4.4 10.5 15.6 11.3 11.0 4.3 12.4 7.0 21.3 33.8 16.8 9.2 15.0 23.6 12.2 65.5 14.5 59.4 7.6 13.5 31.5 14.6 18.5 17.9 98.4 155.2 83.3 111.0 30.0 41.3 61.0 42.3 36.5 57.0 65.8 84.2 72.1 102.8 33.7 47.0 115.5 117.1 63.8 64.3 33.1 46.2 109.4 80.6 136.3 72.7 7.2 63.2 78.0 27.4 16.7 82.3 29.0 18.6 31.0 147.1 65.0 111.6 64.5 250.2 119.1 245.3 179.5 48.5 94.7 163.5 123.4 86.4 31.7 54.9 83.5 115.6 43.7 126.9 20.8 59.8 83.9 165.8 29.1 54.2 205.1 126.8 102.3 85.2 70.6 108.9 54.6 155.1 199.8 31.5 60.2 44.4 42.8 78.6 34.3 71.0 49.6 45.6 94.3 65.1 48.9 42.3 16.2 39.4 66.8 211.5 75.5 45.7 13.7 16.6 14.6 18.0 15.4 13.6 16.1 14.1 15.6 15.0 14.5 17.9 13.0 6.4 7.5 1.0 34.2 40.1 26.5 22.6 14.8 11.2 25.3 39.0 16.8 10.0 13.7 11.0 4.2 38.5 46.1 39.6 19.6 24.3 54.7 14.9 24.3 12.8 7.8 111.7 0.5 37.4 80.0 29.6 13.7 10.7 61.0 32.4 7.9 5.2 89.4 0.0 0.5 35.7 32.6 46.2 86.7 121.2 22.1 52.6 46.2 0.0 47.1 27.4 47.4 1.0 4.3 20.4 18.4 18.8 33.1 21.5 17.3 14.1 13.0 7.9 32.9 27.5 32.4 70.2 54.8 41.0 37.1 23.7 37.3 13.7 45.1 27.3 NUMA1 ENSG00000137497 "Nuclear mitotic apparatus protein 1" Q14980 11 72002864-72080693 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019841, HPA019859, HPA029912" Enhanced Supported Nucleoplasm,Cytosol NA Yes 62000 "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA019841: AB_1854708, HPA019859: AB_1854709, HPA029912: AB_10602811" "unprognostic (1.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.06e-2)" "unprognostic (2.84e-1)" "unprognostic (1.14e-1)" "unprognostic (6.47e-2)" "unprognostic (5.75e-2)" "unprognostic (8.74e-3)" "unprognostic (5.91e-2)" "unprognostic (9.45e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "prognostic favorable (7.92e-4)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (1.49e-1)" "unprognostic (1.39e-1)" 55.2 59.9 27.8 51.1 45.6 69.6 67.1 37.4 40.5 75.4 36.2 77.7 59.6 111.2 43.3 67.9 82.7 62.7 47.6 24.0 33.0 49.9 29.8 65.4 57.9 40.4 34.3 112.3 68.8 98.6 42.1 60.8 41.9 111.4 54.5 46.2 78.1 85.6 82.5 93.8 61.9 86.7 28.4 56.8 59.0 42.4 36.0 79.3 73.9 54.8 53.2 75.2 65.9 83.4 64.4 80.0 97.2 66.4 85.1 88.2 48.8 85.0 97.2 86.4 74.6 83.9 115.5 86.7 72.0 104.0 61.6 134.2 89.7 85.8 78.0 89.9 43.1 105.8 130.4 64.1 69.1 81.1 74.0 94.0 55.7 84.1 84.3 133.0 74.0 76.7 63.4 101.1 59.4 124.2 105.6 45.2 61.2 122.3 57.6 127.9 170.0 67.6 64.2 98.6 117.3 166.6 134.9 123.5 123.6 42.3 166.4 47.1 103.0 90.6 69.9 130.1 56.9 64.8 69.7 120.0 61.1 38.0 53.0 3.7 4.1 1.9 6.4 2.3 4.7 3.4 4.0 5.0 3.5 5.8 4.9 3.6 2.8 5.0 4.4 8.2 5.2 6.0 27.8 45.6 37.4 40.5 24.0 33.0 40.4 34.3 41.9 28.4 36.0 83.4 52.4 41.7 41.3 42.7 36.6 25.9 30.1 25.3 74.0 60.7 62.3 63.4 5.7 34.3 32.2 53.3 73.0 25.5 42.6 56.3 17.6 27.9 31.9 55.5 48.5 44.9 47.4 43.3 27.5 32.1 13.4 41.9 57.6 92.8 31.0 84.7 37.9 23.6 28.7 52.2 34.0 68.3 32.6 32.1 24.9 17.8 69.0 36.3 19.6 33.7 26.8 51.8 53.5 27.6 58.9 30.9 31.2 50.8 40.8 29.6 57.0 26.9 35.4 59.8 39.5 64.3 36.9 14.8 21.4 51.9 28.1 45.0 44.8 44.2 52.2 26.0 NUMB C14orf41 ENSG00000133961 "NUMB endocytic adaptor protein" P49757 14 73275107-73458617 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 290.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002874, CAB011478" Approved Enhanced "Cell Junctions" NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "CAB011478: AB_443023, HPA002874: " "unprognostic (5.28e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.32e-3)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (2.43e-1)" "unprognostic (9.49e-2)" "unprognostic (1.33e-2)" "unprognostic (4.08e-3)" "unprognostic (2.65e-3)" "unprognostic (4.14e-2)" "prognostic favorable (2.32e-6)" "unprognostic (9.12e-2)" "unprognostic (1.63e-1)" "unprognostic (3.92e-2)" "unprognostic (2.87e-1)" 35.6 25.9 17.3 37.7 19.2 35.5 33.0 20.4 23.4 34.3 22.0 46.3 46.6 35.6 25.9 40.0 39.0 41.7 28.8 20.9 17.6 41.3 52.1 52.8 24.7 20.3 19.5 33.9 37.3 40.5 20.2 44.4 19.7 29.5 42.2 20.4 36.8 31.6 21.1 32.6 47.4 37.6 18.1 40.4 36.8 20.3 19.4 27.6 39.0 24.1 30.9 40.5 34.0 18.2 70.2 46.9 33.3 30.2 65.8 99.6 45.3 64.9 87.2 51.2 54.1 57.0 86.0 31.9 39.7 80.7 37.8 45.2 39.8 66.6 77.2 48.9 22.2 25.5 28.2 37.3 69.7 23.7 57.5 56.0 70.3 126.2 74.8 56.2 112.3 49.2 47.0 37.1 65.6 62.9 43.3 32.8 15.4 78.9 50.1 27.6 46.7 21.6 71.2 105.3 13.6 35.3 81.0 54.2 33.4 55.9 81.3 34.5 108.8 76.2 42.7 49.3 28.2 30.9 38.9 29.2 153.1 27.4 34.3 91.9 93.3 96.8 12.6 76.4 13.2 22.6 12.7 14.0 68.7 21.4 12.9 11.8 290.3 12.8 102.8 12.8 17.9 64.5 17.3 19.2 20.4 23.4 20.9 17.6 20.3 19.5 19.7 18.1 19.4 18.2 54.4 64.1 49.0 108.4 53.6 42.8 27.7 38.6 42.1 30.7 38.4 26.0 22.0 44.3 50.0 55.2 81.3 26.0 29.9 59.3 25.4 27.9 11.9 68.2 35.0 59.2 40.7 22.9 151.1 26.4 31.0 37.5 43.8 56.6 24.1 26.3 52.1 51.0 42.6 15.2 78.8 39.4 36.7 91.5 109.7 8.1 45.1 94.1 46.2 141.5 117.3 42.6 39.1 62.4 81.8 46.9 39.3 36.9 40.9 37.1 64.7 43.2 56.9 46.4 26.3 22.8 29.7 59.2 32.7 35.6 46.5 34.3 25.6 16.7 37.5 44.6 NUP210L ENSG00000143552 "Nucleoporin 210 like" Q5VU65 1 153992685-154155116 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 26.6" "Cell type enhanced" "Detected in some" "Early spermatids: 20.3;Inhibitory neurons: 8.4;Late spermatids: 8.5;Oligodendrocytes: 19.2;Spermatocytes: 28.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 47 "MCF7: 15.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047195, HPA064245, HPA066707" Enhanced Approved "Nuclear bodies" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear bodies" "HPA047195: AB_2679980, HPA064245: AB_2685224, HPA066707: AB_2685706" "unprognostic (2.11e-1)" "unprognostic (1.78e-1)" "unprognostic (3.01e-1)" "unprognostic (1.80e-2)" "unprognostic (1.63e-2)" "unprognostic (1.72e-3)" "unprognostic (6.90e-2)" "unprognostic (1.79e-3)" "unprognostic (3.45e-2)" "unprognostic (5.57e-2)" "unprognostic (4.51e-4)" "unprognostic (1.15e-1)" "unprognostic (9.35e-10)" "unprognostic (4.20e-2)" "unprognostic (3.78e-2)" "unprognostic (7.45e-2)" "unprognostic (4.09e-2)" 0.1 0.0 0.2 0.0 0.7 0.1 0.0 2.4 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.7 0.6 0.1 0.1 0.0 0.3 0.0 0.8 0.1 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.0 26.6 0.5 0.0 0.2 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.7 2.4 0.9 0.4 0.3 0.7 0.6 0.8 0.3 0.5 2.3 0.6 0.0 0.0 6.2 0.5 0.3 0.1 0.1 0.0 0.0 0.3 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 20.3 0.7 0.6 0.9 0.0 0.4 7.0 0.2 0.1 0.5 0.0 1.5 0.0 0.1 0.0 0.0 0.2 0.0 8.4 0.1 0.0 0.0 0.6 8.5 0.9 0.8 0.0 2.8 0.0 0.0 0.0 4.5 19.2 0.0 0.0 1.2 1.7 0.1 0.0 0.1 0.1 0.0 6.6 1.8 0.3 28.2 5.1 0.3 0.6 0.0 0.4 0.1 0.1 0.3 NUP214 "CAIN, CAN, D9S46E, N214" ENSG00000126883 "Nucleoporin 214" P35658 9 131125586-131234663 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 124.2" "Cell type enhanced" "Detected in all" "Early spermatids: 281.4;Granulosa cells: 169.2;Kupffer cells: 274.8;Late spermatids: 404.3;monocytes: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 425.3;neutrophil: 1259.6" "Group enriched" "Detected in all" 5 "granulocytes: 1259.6;monocytes: 425.3" "Cell line enhanced" "Detected in all" "K-562: 260.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.30e-1)" "unprognostic (9.51e-3)" "unprognostic (9.92e-3)" "unprognostic (1.15e-1)" "unprognostic (7.42e-2)" "unprognostic (8.31e-2)" "unprognostic (1.07e-3)" "unprognostic (2.10e-2)" "unprognostic (3.35e-1)" "unprognostic (4.95e-1)" "unprognostic (6.60e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.49e-2)" "unprognostic (6.84e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" 29.0 21.2 17.0 18.5 20.9 42.0 26.0 19.1 23.2 21.1 17.7 23.1 11.8 21.1 17.5 33.0 22.6 12.3 26.1 18.0 18.2 43.8 32.0 22.7 15.1 20.9 19.6 22.1 32.8 16.0 21.5 14.4 20.1 21.9 13.4 15.2 21.3 12.2 24.0 28.9 23.8 13.0 17.0 68.8 25.6 124.2 20.4 41.8 22.0 13.1 15.4 21.2 22.1 26.3 23.1 31.3 28.1 15.4 20.2 25.1 26.9 20.9 20.4 24.7 20.2 25.2 17.0 36.7 16.8 29.6 26.5 50.1 35.2 24.0 32.6 26.4 16.0 25.7 45.7 45.5 18.3 37.4 23.3 20.7 21.9 31.0 27.5 16.9 25.1 23.2 260.6 20.5 28.0 39.4 52.8 41.8 27.7 30.2 27.1 17.8 35.2 36.4 25.0 24.8 21.4 24.8 35.5 30.0 17.3 18.4 41.0 90.3 23.5 44.9 25.2 30.1 31.6 18.8 49.7 39.0 22.3 20.7 28.2 53.2 425.3 174.5 6.7 181.7 8.1 13.5 8.4 6.4 162.2 11.8 6.5 7.5 1259.6 10.2 154.8 16.9 5.2 211.2 17.0 20.9 19.1 23.2 18.0 18.2 20.9 19.6 20.1 17.0 20.4 26.3 24.3 19.2 17.9 46.7 27.8 8.7 11.3 11.4 20.5 31.0 14.7 14.6 21.3 10.0 15.6 23.9 45.9 13.2 31.2 18.6 9.8 10.4 281.4 17.3 20.1 18.6 20.4 20.4 39.7 15.2 11.8 17.8 20.4 18.8 8.8 169.2 21.4 14.5 81.2 16.8 41.1 16.6 22.4 274.8 35.3 404.3 23.3 120.6 10.6 50.6 224.1 14.9 33.0 41.2 75.8 13.8 7.7 20.3 23.4 14.3 15.0 9.1 19.8 32.3 6.6 24.4 36.3 90.8 49.8 16.5 10.9 10.9 22.4 23.0 17.6 11.3 NUP93 KIAA0095 ENSG00000102900 "Nucleoporin 93" Q8N1F7 16 56730118-56850286 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017937 Uncertain NA NA 38000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA017937: AB_1854726" "unprognostic (6.31e-2)" "unprognostic (3.22e-2)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (3.99e-3)" "unprognostic (2.78e-3)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.18e-2)" "unprognostic (9.35e-3)" "unprognostic (5.22e-2)" "unprognostic (4.55e-2)" "unprognostic (1.97e-1)" "unprognostic (2.66e-2)" "unprognostic (3.71e-1)" "unprognostic (1.85e-1)" "unprognostic (9.68e-2)" "unprognostic (3.74e-2)" 17.9 13.9 13.2 21.3 17.4 52.7 15.5 6.8 23.9 15.3 0.2 17.7 9.9 16.9 12.4 22.3 15.3 12.4 14.2 30.6 10.7 12.8 9.3 15.3 27.7 10.7 9.3 14.9 14.2 14.8 10.8 19.1 9.9 17.7 18.1 31.7 12.2 12.7 20.0 21.6 14.5 19.5 8.3 24.2 15.2 39.8 11.4 34.1 34.3 14.2 30.3 17.1 16.1 11.5 71.3 84.5 71.6 81.0 25.9 34.8 81.0 58.7 48.2 156.2 100.1 119.4 66.1 107.7 60.4 54.9 54.2 120.6 143.3 90.1 149.8 34.0 81.3 72.6 64.7 97.3 35.0 96.7 82.8 29.3 35.7 104.2 64.7 31.6 90.8 95.3 87.8 22.3 72.3 52.4 136.2 81.1 92.1 44.2 95.4 163.9 129.4 108.9 53.1 47.8 66.6 44.1 159.1 54.6 47.3 77.4 43.0 57.9 55.3 68.1 74.0 57.8 67.5 35.0 60.7 190.2 47.4 88.5 67.5 19.3 49.9 195.7 38.9 77.2 45.2 45.4 28.3 40.9 60.9 45.4 28.7 41.0 11.8 51.8 77.5 28.7 39.7 47.4 13.2 17.4 6.8 23.9 30.6 10.7 10.7 9.3 9.9 8.3 11.4 11.5 11.3 6.4 12.3 17.6 13.4 12.0 13.6 20.7 6.2 68.6 9.0 7.6 11.8 1.5 20.2 9.2 10.4 21.1 9.4 8.6 11.7 24.6 11.7 10.9 8.8 16.5 4.9 33.2 51.1 25.5 31.7 12.8 13.7 10.6 17.2 22.3 10.8 7.2 26.6 38.7 49.4 11.2 24.4 17.8 23.8 7.7 23.3 17.3 16.0 33.7 30.3 11.7 8.2 18.1 22.1 21.4 7.2 13.5 8.1 16.5 3.6 11.0 13.0 20.8 13.1 11.4 27.9 54.6 62.2 14.3 16.1 10.3 13.5 22.3 15.3 18.0 NUP98 "NUP96, Nup98-96, Nup98-Nup96" ENSG00000110713 "Nucleoporin 98 and 96 precursor" P52948 11 3671083-3797792 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Translocation, Transport" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 118.7;Late spermatids: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (7.41e-2)" "unprognostic (2.13e-1)" "unprognostic (7.71e-3)" "unprognostic (3.40e-1)" "unprognostic (4.08e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-2)" "unprognostic (1.83e-2)" "unprognostic (7.76e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (5.09e-1)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" 22.9 14.7 7.2 25.1 8.4 76.0 25.3 15.1 12.4 21.8 13.8 21.1 17.8 22.2 20.7 23.1 20.8 21.6 20.8 7.2 8.8 19.3 31.9 23.4 27.6 9.8 10.5 28.4 24.0 25.7 16.7 25.6 8.3 21.9 23.6 23.2 23.3 22.3 41.9 21.2 17.7 23.4 7.1 21.9 17.6 78.4 9.1 34.4 29.1 31.0 30.6 32.7 18.6 12.7 81.2 63.7 51.7 54.5 54.7 46.1 44.5 57.9 67.7 78.3 69.9 69.4 97.4 80.6 26.0 68.6 77.1 85.5 90.0 56.1 105.6 56.7 67.0 86.4 51.7 48.1 46.1 111.1 67.5 51.9 37.6 41.8 75.2 33.7 61.9 88.3 109.3 60.6 82.5 33.2 110.2 36.3 64.5 87.8 48.4 65.9 62.6 37.8 43.4 63.4 46.8 31.5 83.4 64.9 38.1 52.0 40.5 43.4 45.9 59.9 51.1 67.5 53.0 37.0 67.0 83.5 41.0 46.5 64.4 40.5 11.7 23.3 15.0 15.0 15.1 12.8 14.7 13.5 14.3 10.8 16.1 14.4 35.2 9.7 9.5 3.9 20.1 13.3 7.2 8.4 15.1 12.4 7.2 8.8 9.8 10.5 8.3 7.1 9.1 12.7 24.7 28.9 25.2 32.7 37.4 49.8 36.3 12.6 34.7 14.9 28.2 24.5 19.5 22.8 20.1 7.3 16.7 22.2 41.6 18.8 3.9 12.2 118.7 32.1 30.4 22.5 21.5 42.5 43.6 11.8 17.5 22.7 42.3 62.0 18.3 16.3 15.7 23.6 16.8 15.2 43.7 15.1 6.1 19.8 51.1 158.6 17.1 29.3 16.0 25.3 24.9 11.1 12.3 31.7 44.4 13.2 16.1 14.3 36.3 25.1 11.8 9.0 16.6 14.1 32.9 36.9 23.2 56.2 31.0 30.3 50.4 46.5 44.5 13.7 19.5 32.5 NUTM1 "C15orf55, DKFZp434O192, FAM22H, NUT" ENSG00000184507 "NUT midline carcinoma family member 1" Q86Y26 15 34343315-34357737 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 19.8" "Cell type enriched" "Detected in some" 6 "Early spermatids: 89.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA040421 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA040421: AB_10793965" "unprognostic (4.14e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-1)" "unprognostic (7.38e-2)" "unprognostic (1.99e-1)" "unprognostic (8.37e-2)" "unprognostic (8.66e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (5.55e-2)" "unprognostic (1.34e-2)" "unprognostic (5.97e-3)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (4.27e-2)" "unprognostic (4.79e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 89.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NUTM2B "bA119F19.1, FAM22B" ENSG00000188199 "NUT family member 2B" A6NNL0 10 79703227-79714681 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" "HPA064635: " "unprognostic (9.51e-2)" "unprognostic (6.09e-2)" "unprognostic (1.21e-2)" "unprognostic (1.10e-1)" "unprognostic (3.63e-1)" "unprognostic (6.60e-2)" "unprognostic (2.47e-2)" "unprognostic (7.66e-2)" "unprognostic (1.33e-2)" "unprognostic (1.95e-1)" "unprognostic (7.79e-3)" "unprognostic (1.15e-1)" "unprognostic (9.70e-2)" "unprognostic (9.97e-2)" "unprognostic (5.72e-2)" "unprognostic (5.37e-2)" "unprognostic (2.32e-2)" 0.6 0.7 1.6 0.7 1.3 1.4 0.6 3.1 1.9 0.6 0.0 0.8 0.2 0.8 0.5 0.6 0.9 0.2 1.5 1.7 0.9 1.6 1.1 0.8 0.7 1.6 0.9 0.9 1.4 0.7 1.8 0.3 1.5 1.1 0.2 0.8 1.0 0.3 1.0 1.1 0.9 0.1 0.3 1.3 0.9 3.4 1.8 0.7 0.9 0.1 0.7 0.5 0.8 1.8 0.7 0.8 1.7 1.0 0.4 0.4 0.7 0.3 0.5 0.4 0.4 0.1 1.5 1.7 0.2 0.4 0.6 0.7 0.1 0.8 0.3 1.1 0.6 1.3 0.2 0.5 0.7 1.2 2.9 1.1 0.4 0.2 0.3 1.5 0.0 2.4 1.9 0.8 0.3 1.4 0.3 2.3 1.6 0.0 0.8 0.4 0.2 0.2 0.5 0.2 0.7 1.8 1.0 1.3 1.7 0.8 0.4 1.4 1.0 0.2 0.3 0.2 0.6 0.3 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.9 1.7 0.9 1.6 0.9 1.5 0.3 1.8 1.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 NUTM2D FAM22D ENSG00000214562 "NUT family member 2D" Q5VT03 10 87357720-87370695 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.2;Cone photoreceptor cells: 4.2;Gastric mucus-secreting cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 12.4;hTCEpi: 11.7" HPA064635 Approved "Nuclear bodies" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear bodies" "HPA064635: " "unprognostic (2.13e-1)" "unprognostic (7.95e-2)" "unprognostic (3.94e-2)" "unprognostic (2.16e-1)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (7.35e-4)" "unprognostic (1.87e-1)" "unprognostic (2.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.46e-1)" "unprognostic (3.57e-1)" "unprognostic (7.76e-3)" "unprognostic (1.00e-2)" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (2.32e-1)" 3.1 3.0 5.3 1.4 7.2 2.4 3.1 4.5 8.4 2.4 0.2 3.6 2.1 3.0 3.4 2.8 3.1 2.6 5.6 4.5 4.9 4.8 4.2 3.3 2.1 8.1 7.0 3.7 4.7 4.1 4.8 2.5 7.0 4.5 2.0 2.7 3.9 2.0 3.8 4.7 3.2 1.3 3.6 3.7 4.0 4.9 7.1 2.5 4.5 2.9 1.6 3.1 3.1 10.5 3.9 2.8 6.1 0.0 1.6 2.3 1.4 1.0 5.0 2.2 2.5 1.8 1.9 3.3 0.9 1.7 1.0 1.8 0.1 2.0 1.0 2.2 2.7 4.9 0.2 2.8 3.8 3.1 12.4 3.7 11.7 2.5 1.9 3.4 2.2 4.3 5.2 0.8 0.5 3.5 2.4 5.2 3.4 0.8 0.3 3.3 0.4 0.1 2.2 0.8 2.4 3.7 1.1 2.6 1.2 2.3 4.9 2.4 5.5 1.5 1.0 1.4 1.8 4.0 2.4 0.9 0.9 1.9 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.2 4.5 8.4 4.5 4.9 8.1 7.0 7.0 3.6 7.1 10.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.9 0.3 0.3 1.2 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.1 0.0 0.0 0.2 1.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.5 0.1 0.0 0.1 0.1 0.1 0.1 ODAM "APin, FLJ20513" ENSG00000109205 "Odontogenic, ameloblast associated" A1E959 4 70196496-70204576 "Cancer-related genes, Predicted intracellular proteins" Biomineralization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "salivary gland: 371.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 4.2;Breast glandular cells: 10.3;Ductal cells: 6.5;Exocrine glandular cells: 8.2;Gastric mucus-secreting cells: 6.6;Glandular and luminal cells: 10.5;Theca cells: 4.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "Hep G2: 31.7;OE19: 21.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA036279, HPA036543, HPA070297" Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm Cytosol "HPA036279: , HPA036543: AB_10669797, HPA070297: " "unprognostic (2.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "unprognostic (3.34e-3)" "unprognostic (1.06e-1)" "unprognostic (1.88e-2)" "unprognostic (3.47e-1)" "unprognostic (3.08e-1)" "unprognostic (3.03e-1)" "unprognostic (2.72e-1)" "unprognostic (1.86e-2)" "unprognostic (2.50e-2)" 0.0 0.8 0.0 2.9 0.0 0.0 0.7 0.0 0.0 0.3 0.1 3.6 1.0 0.1 0.6 0.2 0.1 0.5 0.0 0.0 0.8 1.2 0.0 2.4 0.3 1.2 0.7 0.0 0.5 3.6 0.5 0.3 0.0 1.8 0.8 0.0 371.5 1.4 0.0 0.0 0.7 7.3 0.0 0.0 9.8 0.0 0.2 0.0 4.1 0.0 1.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.7 0.0 0.0 0.2 0.0 0.1 3.2 4.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 10.3 0.4 0.0 1.5 1.3 1.8 0.0 0.4 0.0 0.0 0.0 6.5 0.0 2.3 0.9 0.1 0.0 0.0 0.0 8.2 0.0 0.0 6.6 10.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 4.2 0.5 0.4 OGG1 "HMMH, HOGG1, MUTM, OGH1" ENSG00000114026 "8-oxoguanine DNA glycosylase" O15527 3 9749944-9788219 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027514, CAB047301" Approved Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "CAB047301: , HPA027514: AB_10602189" "unprognostic (6.95e-2)" "unprognostic (7.82e-3)" "unprognostic (7.19e-2)" "unprognostic (1.24e-3)" "unprognostic (9.69e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (5.77e-5)" "unprognostic (7.83e-2)" "unprognostic (2.45e-2)" "unprognostic (3.43e-3)" "unprognostic (9.66e-3)" "unprognostic (4.23e-2)" "prognostic favorable (2.65e-4)" "unprognostic (2.06e-2)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.59e-1)" 12.6 13.8 18.6 13.2 18.3 12.2 12.8 20.5 19.6 18.2 12.5 14.8 18.9 17.1 10.3 9.6 16.9 8.4 11.8 19.6 15.8 30.3 20.7 10.7 26.2 18.8 16.7 22.5 10.6 6.6 10.8 8.6 17.9 15.7 8.1 12.1 12.2 10.1 7.2 9.6 17.2 9.8 16.2 15.2 12.4 8.6 17.5 13.5 13.1 8.0 21.2 15.3 14.3 17.4 11.3 20.7 20.3 13.1 19.9 22.3 38.4 14.5 14.8 21.6 25.6 19.9 10.8 68.5 9.5 18.3 34.1 10.8 12.1 15.9 9.0 25.1 17.6 33.9 32.5 29.3 20.7 13.3 20.9 22.3 20.0 37.4 16.0 17.4 27.3 9.6 11.0 10.9 20.9 21.3 10.7 13.2 11.0 10.3 29.3 7.8 13.7 22.4 12.4 5.7 9.0 15.9 18.4 15.2 11.5 10.4 23.7 22.9 17.5 21.9 22.7 17.2 24.0 10.7 16.9 35.9 17.4 37.9 13.7 15.1 10.9 20.7 18.7 9.0 18.4 13.9 15.8 15.3 9.8 16.5 12.1 11.5 2.9 27.0 7.3 15.9 21.0 10.9 18.6 18.3 20.5 19.6 19.6 15.8 18.8 16.7 17.9 16.2 17.5 17.4 9.5 0.0 3.4 15.3 16.7 5.5 8.9 8.3 9.1 20.9 6.7 7.4 2.3 10.0 4.9 9.2 35.5 6.4 16.5 9.0 11.7 7.7 0.9 5.0 12.2 10.4 18.0 22.3 11.2 6.7 10.1 11.7 6.1 4.4 2.5 10.0 10.0 11.8 18.0 8.4 9.2 8.8 6.1 9.0 5.8 1.8 14.3 9.3 7.2 10.3 15.8 11.3 27.8 13.0 9.9 8.8 11.0 13.5 10.0 5.2 47.1 86.3 4.1 34.7 26.3 11.1 10.3 10.2 21.5 5.0 4.5 4.0 12.9 12.0 14.0 5.4 OLIG2 "BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17" ENSG00000205927 "Oligodendrocyte transcription factor 2" Q13516 21 33025935-33029196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 87.2" "Group enriched" "Detected in some" 22 "Oligodendrocyte precursor cells: 124.1;Oligodendrocytes: 39.9" "Cancer enriched" "Detected in some" 52 "glioma: 46.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "eosinophil: 19.0" "Lineage enriched" "Detected in single" 190 "granulocytes: 19.0" "Cell line enhanced" "Detected in some" "HMC-1: 56.2;NB-4: 41.8;THP-1: 35.9;WM-115: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003254, CAB019381" Enhanced Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Plasma membrane" "CAB019381: , HPA003254: AB_1854795" "unprognostic (5.14e-1)" "unprognostic (4.56e-1)" "unprognostic (1.44e-2)" "unprognostic (8.27e-2)" "unprognostic (3.24e-2)" "unprognostic (4.34e-2)" "unprognostic (4.81e-2)" "unprognostic (5.41e-2)" "unprognostic (1.39e-1)" "unprognostic (5.78e-5)" "unprognostic (2.76e-1)" 0.0 0.0 46.4 0.0 58.3 0.0 0.0 52.7 54.4 0.0 21.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 48.1 49.8 0.0 0.0 0.0 0.0 58.0 54.6 0.0 0.0 0.0 0.1 0.0 51.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 48.0 0.0 0.1 0.0 50.9 0.0 0.0 0.2 0.0 0.0 0.0 87.2 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.5 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.0 1.7 56.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 41.8 3.6 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 35.9 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 1.4 0.0 11.7 2.8 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.4 58.3 52.7 54.4 48.1 49.8 58.0 54.6 51.4 48.0 50.9 87.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 124.1 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 OMA1 "FLJ33782, MPRP-1, YKR087C, ZMPOMA1" ENSG00000162600 "OMA1 zinc metallopeptidase" Q96E52 1 58415384-58546802 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055120 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "HPA055120: AB_2682702" "prognostic favorable (1.63e-4)" "unprognostic (2.67e-2)" "prognostic favorable (7.70e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-1)" "unprognostic (9.57e-2)" "unprognostic (3.94e-3)" "prognostic favorable (8.52e-4)" "unprognostic (8.22e-3)" "unprognostic (6.91e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (9.54e-3)" "unprognostic (2.52e-2)" "unprognostic (3.93e-2)" "unprognostic (1.74e-2)" "unprognostic (5.24e-3)" 11.4 18.7 15.1 14.0 22.8 12.8 19.7 23.1 14.9 16.7 14.9 20.8 14.9 13.5 17.8 13.3 19.4 15.1 19.8 13.0 19.5 28.4 31.1 11.9 23.4 18.8 17.9 13.5 17.9 18.1 10.4 11.5 21.1 20.8 20.0 20.5 19.5 16.7 28.2 12.8 14.2 12.4 15.6 20.2 17.3 8.2 18.3 20.2 20.1 29.9 21.5 14.8 10.5 27.3 31.2 13.0 8.3 7.9 41.7 39.0 24.6 12.7 13.9 10.9 13.7 4.0 18.7 69.8 26.3 13.1 37.8 31.2 31.1 31.3 13.3 55.1 17.9 22.0 10.4 16.1 20.3 54.3 14.7 37.3 33.6 10.4 22.4 24.1 9.3 34.3 42.7 20.1 29.2 19.5 18.0 19.4 12.4 47.4 28.5 22.1 27.7 29.1 23.6 20.5 8.7 4.3 26.0 41.9 37.6 38.4 19.5 20.1 5.4 5.6 10.8 27.8 13.5 16.3 23.4 46.2 16.8 42.2 14.1 20.1 14.4 32.1 19.4 24.1 25.6 35.6 23.7 23.1 15.4 35.0 33.9 31.5 17.2 30.9 35.1 8.2 23.6 15.9 15.1 22.8 23.1 14.9 13.0 19.5 18.8 17.9 21.1 15.6 18.3 27.3 8.4 19.2 11.5 37.9 25.7 6.0 18.2 35.6 13.6 7.8 15.0 12.3 27.2 8.6 33.0 25.8 12.5 22.9 14.4 8.4 25.4 11.2 5.8 31.6 10.8 6.3 6.0 15.6 18.3 5.5 10.0 12.0 5.6 18.4 6.3 10.9 6.4 18.7 15.8 1.7 31.7 17.7 36.7 10.1 9.7 12.7 9.9 12.9 7.2 29.0 11.3 10.9 15.5 52.8 106.5 3.8 10.9 8.6 16.8 12.3 8.5 32.4 63.1 20.5 6.6 12.0 8.6 14.3 13.6 17.3 6.8 18.3 20.7 17.1 14.6 17.1 OR4A16 OR4A16Q ENSG00000181961 "Olfactory receptor family 4 subfamily A member 16" Q8NH70 11 55343151-55344231 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR51E2 PSGR ENSG00000167332 "Olfactory receptor family 51 subfamily E member 2" Q9H255 11 4680171-4697854 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 9.6;prostate: 28.9" "Cell type enriched" "Detected in some" 6 "Enteroendocrine cells: 77.4" "Cancer enriched" "Detected in some" 274 "prostate cancer: 217.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.9;BJ hTERT+: 1.1;hTERT-RPE1: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.98e-3)" "unprognostic (1.91e-1)" "unprognostic (6.09e-3)" "unprognostic (1.57e-2)" "unprognostic (8.00e-4)" "unprognostic (3.61e-2)" "unprognostic (6.27e-2)" "unprognostic (1.66e-1)" "unprognostic (3.05e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-1)" "unprognostic (3.61e-1)" "unprognostic (5.04e-5)" "unprognostic (3.34e-2)" "unprognostic (4.66e-2)" "unprognostic (5.76e-2)" "unprognostic (3.29e-1)" 0.6 0.2 0.3 1.0 0.4 0.1 0.5 0.4 0.5 0.7 0.6 9.6 0.2 1.3 0.3 0.0 0.5 0.3 0.2 0.4 0.2 0.4 0.0 0.0 0.0 0.3 0.3 0.6 0.1 0.0 0.0 4.0 0.4 28.9 2.2 0.1 0.0 2.3 0.4 0.2 0.8 2.1 0.1 0.0 0.4 0.3 0.5 0.0 0.1 0.4 0.0 0.4 0.2 0.7 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.4 0.5 0.4 0.2 0.3 0.3 0.4 0.1 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 77.4 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 OR52N1 ENSG00000181001 "Olfactory receptor family 52 subfamily N member 1" Q8NH53 11 5786471-5791265 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;granulocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA054028 Uncertain NA NA "Cluster 60: Granulocytes - Receptor signaling" "HPA054028: AB_2682348" 0.2 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.3 0.2 0.4 0.2 0.1 0.4 0.1 0.2 0.4 0.7 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ORM1 ENSG00000229314 "Orosomucoid 1" P02763 9 114323056-114326475 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 193 "liver: 42973.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 58657.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 2506.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 47 "neutrophil: 193.9" "Lineage enriched" "Detected in many" 47 "granulocytes: 193.9" "Cell line enriched" "Detected in some" 12 "Hep G2: 1182.7" "CAB006265, HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 945000000000 61000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Golgi apparatus" "CAB006265: AB_425575, HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (3.85e-1)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (1.16e-1)" "unprognostic (4.85e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.35e-4)" "unprognostic (2.10e-1)" "unprognostic (4.38e-2)" "unprognostic (9.32e-3)" "unprognostic (4.51e-2)" 13.4 10.3 0.1 12.7 0.3 223.1 6.6 0.0 0.4 2.7 0.2 1.5 0.1 2.7 0.3 1.9 1.9 1.0 3.4 0.2 0.2 4.9 42973.6 24.4 0.7 0.4 0.2 1.6 8.1 0.0 1.4 1.3 0.1 57.6 0.0 1.1 1.4 0.0 2.0 1.7 2.3 0.3 0.2 51.3 19.2 2.7 0.1 1.2 2.8 0.3 0.1 1.6 2.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 2.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 3.4 0.6 1182.7 0.1 5.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.2 0.0 0.2 1.0 0.1 0.0 0.7 7.1 0.0 0.0 0.4 0.0 0.0 5.7 5.5 0.0 0.0 0.4 102.0 1.2 0.0 0.5 0.0 0.0 1.2 0.6 3.5 0.0 4.3 0.1 0.0 4.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.9 0.0 1.0 0.0 0.0 1.8 0.1 0.3 0.0 0.4 0.2 0.2 0.4 0.2 0.1 0.2 0.1 0.2 0.0 3.2 18.1 0.0 81.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1166.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 1.3 0.2 34.4 0.0 890.4 0.0 4.9 0.3 0.2 0.0 2.5 0.0 0.0 930.9 58657.7 0.1 0.0 0.0 0.0 0.0 1260.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.0 0.3 OSM MGC20461 ENSG00000099985 "Oncostatin M" P13725 22 30262829-30266851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Cytokine, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 118.2" "Group enriched" "Detected in some" 4 "Hofbauer cells: 74.4;Macrophages: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 65.2;neutrophil: 34.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "HDLM-2: 15.7;HL-60: 3.8;HMC-1: 11.1;Karpas-707: 3.5;NB-4: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 39700 "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.15e-2)" "unprognostic (8.80e-3)" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (7.37e-2)" "unprognostic (2.61e-2)" "unprognostic (6.78e-2)" "unprognostic (3.77e-2)" "unprognostic (2.81e-2)" "unprognostic (4.60e-2)" "unprognostic (1.58e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.00e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.82e-1)" 7.2 3.6 0.8 14.3 1.0 118.2 0.8 0.8 4.2 1.2 2.0 1.0 0.5 1.1 0.1 0.8 2.3 6.2 1.4 0.6 1.5 2.0 1.9 7.8 1.6 1.8 0.9 0.5 1.2 0.9 1.5 5.5 1.7 1.0 0.5 0.1 1.1 0.2 0.2 0.2 0.7 3.1 1.6 5.0 0.9 0.4 4.7 2.6 0.8 2.9 0.8 12.7 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.7 0.0 0.3 0.0 0.0 0.0 3.8 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 3.5 0.0 0.0 0.5 6.6 0.0 0.0 0.0 0.6 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.3 0.0 65.2 0.5 2.0 2.0 0.3 6.5 0.0 4.8 2.6 0.8 0.2 0.9 2.4 34.9 4.3 0.1 0.2 1.4 1.6 0.8 1.0 0.8 4.2 0.6 1.5 1.8 0.9 1.7 1.6 4.7 2.9 0.9 9.6 10.6 0.0 3.2 0.8 0.2 0.0 0.0 0.0 0.7 1.8 0.6 0.0 3.7 0.0 0.0 0.8 13.2 0.0 0.0 0.1 0.1 0.6 0.2 1.9 0.0 1.3 0.1 0.0 0.9 1.4 0.0 1.1 15.2 0.0 0.4 0.0 74.4 0.0 0.1 0.1 0.0 6.1 12.4 0.0 0.0 51.6 0.0 0.0 1.8 0.1 1.0 0.0 0.1 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.7 0.2 0.0 0.7 0.4 0.0 0.0 0.3 0.3 0.8 14.2 0.1 0.0 0.0 OTUD7A "C15orf16, CEZANNE2, OTUD7" ENSG00000169918 "OTU deubiquitinase 7A" Q8TE49 15 31475398-31870789 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 20.5" "Cell type enhanced" "Detected in many" "Astrocytes: 135.2;Excitatory neurons: 303.6;Inhibitory neurons: 219.7;Oligodendrocyte precursor cells: 100.0;Oligodendrocytes: 506.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.7;HAP1: 1.0;SCLC-21H: 3.6;SH-SY5Y: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044554 Approved Nucleoli,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli, Cytosol" "HPA044554: AB_10794895" "unprognostic (3.61e-2)" "unprognostic (1.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.25e-3)" "unprognostic (1.29e-1)" "unprognostic (1.03e-4)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (3.24e-3)" "unprognostic (1.34e-1)" "unprognostic (1.79e-11)" "unprognostic (6.78e-2)" "unprognostic (2.76e-1)" "unprognostic (8.27e-2)" "unprognostic (1.79e-1)" 1.2 0.5 6.6 0.4 9.5 0.0 1.0 7.6 8.6 1.3 0.0 1.4 0.3 1.3 0.5 0.7 1.1 0.3 1.3 6.9 5.9 0.9 0.4 0.8 0.4 8.5 6.9 0.9 1.4 1.2 1.5 0.0 8.2 0.6 0.4 1.6 0.7 0.4 1.1 2.6 0.9 0.6 5.6 0.6 0.8 4.1 8.3 0.3 1.0 0.2 0.4 0.8 0.8 20.5 0.0 0.0 0.1 1.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.4 0.8 0.0 0.2 0.1 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.3 0.5 0.0 0.0 0.1 3.6 1.8 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 9.5 7.6 8.6 6.9 5.9 8.5 6.9 8.2 5.6 8.3 20.5 3.5 3.2 0.0 135.2 0.1 0.4 0.7 0.0 1.8 25.7 1.1 1.3 3.2 0.0 0.6 1.8 2.1 0.0 4.3 1.3 0.0 0.5 1.4 0.4 1.2 1.3 3.6 0.0 303.6 1.0 0.1 1.8 0.5 0.4 0.0 1.0 1.4 0.8 0.2 25.2 219.7 1.7 0.0 0.0 0.3 2.0 0.9 0.3 1.8 28.1 0.2 3.9 13.4 100.0 506.1 0.3 0.7 2.6 2.6 1.9 0.4 1.7 0.0 3.1 0.0 4.1 1.5 4.6 8.3 1.8 0.4 0.1 3.1 0.9 1.5 1.0 P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 31.2;lymphoid tissue: 40.1" "Group enriched" "Detected in some" 4 "B-cells: 42.0;dendritic cells: 56.2;monocytes: 26.1;NK-cells: 56.7;Plasma cells: 49.3;T-cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 119.2;MOLT-4: 60.6;NB-4: 59.6;RPMI-8226: 74.3;THP-1: 73.7;U-266/70: 96.8;U-698: 192.8;U-937: 60.6" "Low region specificity" "Detected in single" HPA003631 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.80e-5)" "prognostic favorable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favorable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" 3.5 4.6 0.4 19.2 0.5 31.2 2.4 0.8 1.1 0.7 0.8 3.4 3.4 0.8 0.9 1.3 0.7 3.8 4.9 0.2 0.7 3.6 1.9 3.0 40.1 1.5 0.5 1.1 2.1 2.1 2.1 1.2 0.9 1.5 3.2 0.7 3.4 1.1 2.6 1.8 7.5 1.4 0.5 20.0 5.1 0.4 1.4 16.4 7.9 1.4 33.4 4.4 0.5 1.8 0.6 0.5 0.5 1.5 0.0 0.0 1.3 0.2 0.1 0.0 0.1 0.4 0.7 119.2 0.6 0.0 0.5 0.5 0.0 0.1 0.0 4.7 0.4 1.0 1.3 6.1 0.1 53.2 12.3 0.1 0.1 0.1 0.0 1.1 0.0 35.1 1.1 48.9 0.1 0.1 60.6 59.6 0.7 0.1 1.3 54.1 0.6 74.3 0.1 0.9 0.2 0.8 0.4 1.1 0.3 1.1 0.6 73.7 0.3 1.0 1.1 0.5 0.3 96.8 19.6 192.8 0.2 60.6 0.2 49.9 18.9 31.1 58.6 12.7 53.6 34.2 44.5 55.8 13.6 38.3 34.7 36.4 11.3 37.5 5.2 3.6 37.6 53.3 0.4 0.5 0.8 1.1 0.2 0.7 1.5 0.5 0.9 0.5 1.4 1.8 5.9 0.0 1.8 0.3 42.0 0.4 0.0 0.0 0.0 0.7 0.3 0.0 1.2 0.0 0.6 1.8 0.0 0.0 56.2 0.1 0.0 0.0 0.0 0.1 0.1 5.2 0.0 9.9 0.7 0.2 0.0 0.4 2.6 0.1 1.3 0.3 3.9 0.3 1.9 0.0 0.7 0.0 0.0 11.2 1.8 0.0 0.0 8.7 1.8 1.9 26.1 0.0 56.7 1.0 0.4 0.0 0.0 0.0 49.3 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.0 0.4 0.0 40.7 0.9 0.2 0.0 PABPC1 "PAB1, PABP1, PABPC2, PABPL1" ENSG00000070756 "Poly(A) binding protein cytoplasmic 1" P11940 8 100685816-100722809 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Nonsense-mediated mRNA decay" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011536, HPA045423, HPA067156" Supported Supported Cytosol NA NA 3900000 "Cluster 39: Non-specific - mRNA processing" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Cytosol "CAB011536: AB_777008, HPA045423: AB_2679320, HPA067156: AB_2685793" "unprognostic (5.00e-2)" "unprognostic (2.64e-2)" "unprognostic (3.18e-1)" "unprognostic (4.50e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.93e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (2.51e-3)" "unprognostic (5.70e-2)" "unprognostic (1.50e-2)" "unprognostic (3.21e-3)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.70e-12)" "unprognostic (6.22e-2)" "unprognostic (2.55e-1)" "unprognostic (6.98e-3)" "unprognostic (1.40e-2)" 627.6 341.5 48.8 490.8 73.4 364.0 575.7 54.9 58.6 700.3 86.2 524.3 450.2 453.5 68.3 1353.3 437.0 227.1 233.8 35.3 80.2 296.4 347.7 490.3 542.4 104.1 58.7 724.0 728.0 126.7 167.7 214.5 92.2 473.9 270.3 80.2 1287.6 172.7 197.7 732.4 502.0 226.5 64.1 483.1 524.7 507.9 92.7 421.0 303.4 75.8 532.3 630.5 853.3 81.6 2069.1 644.4 372.2 842.0 585.0 1050.0 793.4 504.4 593.5 451.8 468.7 791.5 1107.8 3230.4 1609.1 809.5 291.3 792.4 554.6 1092.3 459.5 758.2 555.4 1713.1 302.2 562.6 835.7 673.3 891.0 1338.6 1050.2 554.8 2126.1 950.7 690.8 1071.8 1339.4 1120.1 477.5 857.3 2617.8 949.5 882.3 1487.3 929.6 967.5 541.7 1074.2 301.8 953.1 629.2 650.1 415.8 548.6 1200.7 513.2 1031.7 949.5 1005.1 512.4 809.4 723.9 897.9 753.6 606.1 1523.2 609.7 1378.1 538.8 122.8 401.3 131.2 159.3 405.2 348.9 297.4 333.0 264.3 421.4 263.0 437.4 370.4 112.5 306.9 468.5 277.2 301.5 568.0 48.8 73.4 54.9 58.6 35.3 80.2 104.1 58.7 92.2 64.1 92.7 81.6 348.4 371.8 939.1 28.7 1089.1 787.4 1075.3 735.0 1067.7 66.5 1036.1 641.2 139.7 459.0 1020.8 110.3 50.1 454.2 872.8 457.0 264.1 467.0 1727.8 352.1 628.4 523.0 477.1 999.1 42.4 769.0 860.8 458.8 530.1 436.1 1054.1 357.3 570.8 308.3 615.5 72.3 34.1 853.8 360.1 1520.8 1162.9 306.0 498.9 1144.3 370.0 53.4 1583.7 167.7 679.7 29.7 41.1 626.9 698.0 424.3 674.4 655.3 446.1 388.4 473.5 88.4 499.6 530.4 876.7 1433.1 476.0 929.6 765.3 777.9 1041.1 408.3 1061.2 1296.9 PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144284-117176894 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 250000 "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoli, Plasma membrane" "HPA051836: AB_2681630" "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavorable (9.44e-4)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favorable (4.25e-4)" "prognostic unfavorable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" 23.1 34.3 35.1 21.2 42.2 41.2 20.6 43.9 45.0 20.8 28.4 21.7 22.4 23.8 22.7 23.9 20.9 19.9 28.2 33.9 45.4 25.3 23.8 21.7 20.7 47.6 45.0 23.3 20.3 21.9 24.5 25.4 51.0 22.3 20.0 23.2 17.4 16.1 15.7 22.0 19.4 20.4 48.7 20.4 23.0 30.0 43.6 21.5 31.9 20.3 22.2 26.9 20.9 51.6 43.4 48.5 54.9 79.7 60.1 41.7 42.6 71.0 61.7 38.8 35.2 89.2 92.9 46.6 99.4 85.8 38.7 67.7 80.6 92.0 50.9 41.8 31.1 120.0 41.3 57.9 53.8 42.1 44.0 46.6 71.7 77.4 96.7 42.4 64.8 25.6 65.0 34.6 60.3 27.7 40.8 61.7 50.4 60.0 37.8 44.9 62.2 51.2 59.8 66.7 60.9 80.5 82.2 61.6 28.1 46.6 68.4 35.6 103.8 70.4 46.3 34.8 51.4 10.8 17.9 61.5 28.3 78.8 60.4 63.4 51.4 48.6 39.0 58.7 46.4 43.8 44.7 41.0 37.4 41.2 45.8 49.2 63.7 33.1 66.3 27.4 35.1 53.1 35.1 42.2 43.9 45.0 33.9 45.4 47.6 45.0 51.0 48.7 43.6 51.6 48.5 28.9 34.8 17.9 41.4 122.4 44.5 45.9 54.7 38.6 55.4 32.1 37.6 58.6 32.8 66.2 47.9 40.4 44.4 48.0 46.9 61.3 13.1 63.6 54.8 64.8 82.6 39.4 29.2 39.5 86.7 40.8 33.6 78.4 19.0 36.8 79.6 47.0 43.0 47.1 32.5 41.8 36.7 65.4 175.9 13.7 45.4 52.1 49.8 20.6 59.3 36.2 21.6 13.0 61.2 99.0 50.5 34.3 28.9 67.0 33.7 54.8 32.9 38.3 13.1 42.8 40.0 54.7 84.7 53.2 115.9 54.6 41.6 35.2 45.4 50.6 PAGE4 "CT16.7, GAGEC1, PAGE-4" ENSG00000101951 "PAGE family member 4" O60829 X 49829260-49834264 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 871.9;placenta: 1023.1" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 13314.7;Syncytiotrophoblasts: 8524.1" "Group enriched" "Detected in some" 17 "liver cancer: 14.8;prostate cancer: 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.2;U-266/70: 11.7;U-266/84: 45.1" "Not detected" "Not detected" HPA023880 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Golgi apparatus" "HPA023880: AB_1854930" "unprognostic (8.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-3)" "unprognostic (5.37e-2)" 0.3 5.7 0.1 0.3 0.2 0.0 0.0 0.1 0.5 7.0 0.1 0.2 0.4 51.2 871.9 0.0 21.4 0.0 0.4 0.1 0.2 3.1 0.3 0.2 0.0 0.1 0.1 3.7 2.5 0.0 1.3 1023.1 0.1 171.8 0.0 0.0 0.6 77.2 2.3 0.0 0.3 24.2 0.0 0.3 0.2 5.6 0.1 0.1 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.1 0.0 0.1 11.7 45.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13314.7 0.0 0.0 0.0 0.0 4.4 1.9 72.5 25.9 0.0 0.0 0.0 0.0 905.4 72.5 0.0 1.9 0.0 0.0 0.0 0.0 1052.1 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 48.8 20.7 0.0 0.0 8524.1 0.3 0.0 0.0 0.1 PALB2 "FANCN, FLJ21816" ENSG00000083093 "Partner and localizer of BRCA2" Q86YC2 16 23603160-23641310 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB014895, HPA057000" Approved Supported Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB014895: , HPA057000: AB_2683307" "unprognostic (1.11e-1)" "unprognostic (5.67e-3)" "prognostic favorable (2.83e-5)" "unprognostic (1.43e-2)" "unprognostic (6.22e-2)" "unprognostic (1.61e-2)" "unprognostic (2.00e-3)" "unprognostic (5.18e-2)" "unprognostic (2.46e-2)" "unprognostic (2.00e-2)" "prognostic unfavorable (2.35e-5)" "unprognostic (2.05e-2)" "unprognostic (1.04e-2)" "unprognostic (2.72e-1)" "unprognostic (1.25e-1)" "unprognostic (7.20e-2)" "unprognostic (3.21e-1)" 5.8 5.6 6.2 4.4 6.5 3.5 6.4 9.8 10.7 7.1 6.2 6.1 6.5 5.6 5.6 10.1 5.4 3.3 4.7 6.2 6.1 7.9 9.9 4.8 6.3 6.0 6.2 6.2 6.0 5.8 5.1 3.8 6.2 5.3 5.3 8.6 6.0 4.0 5.4 9.0 7.0 4.0 5.7 7.8 5.7 9.8 6.6 6.4 5.3 4.8 6.9 6.6 7.2 7.0 17.3 13.1 15.4 10.8 12.6 9.4 13.9 12.0 18.4 19.7 23.6 11.2 17.3 18.2 8.7 8.6 15.0 15.2 13.9 19.8 23.4 10.8 8.1 11.2 18.2 31.8 11.7 20.5 17.3 11.2 20.3 18.7 20.7 10.9 10.6 17.1 23.4 9.4 17.2 17.4 21.2 21.3 34.3 12.5 7.6 24.2 18.9 24.7 15.2 15.2 11.2 11.3 12.5 13.5 16.7 13.4 12.9 13.9 7.7 23.1 8.7 11.2 13.2 11.2 19.0 18.3 15.4 14.8 14.3 6.4 1.8 1.8 2.1 2.3 2.6 1.8 2.4 2.7 2.0 1.4 2.6 2.1 0.1 2.1 4.5 1.5 1.7 1.1 6.2 6.5 9.8 10.7 6.2 6.1 6.0 6.2 6.2 5.7 6.6 7.0 4.7 12.8 4.2 8.5 5.1 0.9 3.5 5.4 2.2 4.8 4.0 3.7 4.8 2.8 8.2 3.7 4.2 2.9 3.8 2.4 3.9 5.8 6.8 2.3 5.1 4.8 1.2 4.6 7.4 5.0 2.0 4.4 4.1 2.6 5.1 7.7 3.3 4.7 3.7 1.7 8.0 3.4 2.0 5.0 1.5 3.6 4.7 5.1 1.8 5.6 8.4 4.8 5.2 7.1 5.9 8.6 2.5 6.4 4.2 5.3 4.6 5.4 8.3 7.5 6.6 4.7 3.0 30.0 17.7 5.4 2.7 1.2 3.7 6.9 4.8 4.1 PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153791-116402321 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 72.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 92.2;Collecting duct cells: 165.5;Endometrial stromal cells: 101.3;Proximal tubular cells: 51.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 50.0;ASC TERT1: 37.8;HSkMC: 137.4;U-138 MG: 36.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" NA NA 78000000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" 4.1 1.5 0.7 1.8 0.2 0.0 0.8 0.5 0.9 4.2 2.2 2.0 0.3 3.9 0.6 2.5 3.1 2.0 2.6 0.3 1.6 3.8 0.3 1.9 1.2 2.5 2.5 2.5 0.8 9.1 0.4 72.3 2.0 1.1 1.5 1.0 0.4 2.1 0.3 0.9 0.9 4.2 0.4 0.3 1.1 0.8 1.6 0.8 1.0 1.4 1.0 4.5 2.4 1.3 0.0 14.9 22.3 0.0 50.0 37.8 0.0 12.2 21.4 3.3 5.6 0.0 0.0 0.0 0.0 8.6 1.1 1.7 0.0 0.0 15.6 0.0 0.0 2.6 12.8 0.1 24.3 0.0 0.0 137.4 0.0 16.4 1.9 26.9 0.1 0.0 0.5 0.0 3.8 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.0 0.6 0.1 0.1 1.2 1.8 0.0 0.0 6.8 0.0 0.0 28.9 36.3 1.8 1.0 1.4 0.0 0.0 0.0 25.8 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.5 0.9 0.3 1.6 2.5 2.5 2.0 0.4 1.6 1.3 0.2 0.0 1.5 3.9 1.0 2.9 0.2 4.0 92.2 17.6 0.8 0.4 3.4 0.0 1.6 165.5 12.5 0.5 0.1 0.1 9.8 5.9 20.1 4.7 101.3 1.4 0.0 0.0 10.0 0.9 19.5 31.8 0.5 2.6 1.3 10.4 4.6 0.1 0.4 0.0 19.6 0.0 0.0 0.0 5.8 17.9 14.3 1.0 1.8 7.5 0.0 2.5 1.0 15.1 2.9 0.3 0.0 8.6 1.2 1.2 0.2 51.5 1.6 2.9 0.0 3.3 10.9 2.2 0.6 19.7 1.1 14.0 1.3 0.2 0.1 0.3 PARP1 "ADPRT, ARTD1, PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360210-226408154 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "DNA-binding, Glycosyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 469.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727" Supported Supported Enhanced Nucleoplasm,Nucleoli NA NA 150000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Nucleoli "CAB000147: AB_430876, CAB003839: AB_365493, CAB003840: AB_562187, CAB075726: AB_2665732, CAB075727: AB_2665733, HPA045168: AB_2679240" "unprognostic (2.02e-1)" "unprognostic (9.40e-2)" "unprognostic (7.44e-3)" "unprognostic (1.32e-1)" "unprognostic (4.29e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (3.40e-4)" "unprognostic (2.20e-1)" "unprognostic (3.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (2.38e-2)" "unprognostic (1.82e-1)" "unprognostic (3.14e-2)" "unprognostic (2.64e-1)" 32.0 26.4 33.9 63.9 41.9 29.4 29.5 46.2 33.2 26.2 20.6 43.5 29.3 30.2 19.8 31.3 28.9 20.4 55.1 30.3 36.2 22.4 37.1 27.4 125.5 48.4 39.7 27.5 50.8 94.7 38.0 58.2 47.7 40.7 37.2 44.9 28.9 46.4 94.5 21.1 36.8 45.6 41.9 57.7 29.6 40.5 40.9 64.6 28.4 70.2 150.8 38.7 24.6 58.1 182.4 108.9 295.4 209.3 75.9 61.3 137.1 101.3 119.1 178.2 144.9 175.4 98.1 559.3 147.2 80.9 77.9 135.1 411.6 132.4 144.4 204.1 396.6 216.2 135.9 114.5 44.6 372.2 93.3 61.7 50.5 144.2 101.3 49.3 140.5 132.2 346.9 291.8 94.1 99.6 114.7 110.0 476.2 290.5 165.1 334.2 484.5 533.4 76.4 144.5 264.0 229.2 165.2 190.3 100.1 205.3 159.6 225.8 99.3 93.3 140.9 120.6 235.1 110.9 151.8 472.6 78.2 125.7 214.3 11.1 11.7 12.3 31.2 20.5 45.3 72.2 37.3 36.7 28.2 69.9 28.2 32.5 2.2 22.0 42.3 16.2 49.3 25.7 33.9 41.9 46.2 33.2 30.3 36.2 48.4 39.7 47.7 41.9 40.9 58.1 33.4 54.5 73.6 13.7 169.1 72.3 83.9 56.4 51.2 96.1 58.8 43.3 115.0 44.3 69.8 57.0 141.8 469.2 53.8 27.7 72.4 88.9 34.1 53.3 66.5 62.0 75.0 100.5 16.5 107.0 111.7 49.8 37.8 55.2 122.1 116.2 34.2 69.4 139.6 90.9 17.5 50.0 57.0 47.8 35.7 20.5 40.0 48.3 62.2 16.9 76.9 80.1 95.8 10.1 31.9 48.5 24.2 35.0 186.9 82.8 25.6 48.5 56.4 118.1 46.0 58.7 48.0 88.8 199.6 77.2 48.2 137.6 85.0 103.5 61.9 41.7 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PATZ1 "dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG" ENSG00000100105 "POZ/BTB and AT hook containing zinc finger 1" Q9HBE1 22 31325804-31346346 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047893, HPA048315" Approved Supported Nucleoplasm No No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA047893: AB_2680201, HPA048315: AB_2680353" "unprognostic (3.25e-1)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (8.34e-3)" "prognostic favorable (8.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-3)" "unprognostic (1.76e-1)" "prognostic favorable (8.54e-8)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" "prognostic favorable (7.79e-6)" 10.2 10.5 16.0 11.4 18.1 15.8 12.1 16.4 16.1 14.5 11.1 14.8 9.9 18.7 14.2 6.1 22.2 9.3 10.8 14.7 16.0 11.6 11.8 11.2 20.3 18.4 16.7 27.3 13.5 21.0 10.5 9.3 17.6 13.1 6.9 14.9 18.7 17.0 10.5 7.9 12.7 12.2 17.1 15.7 11.1 8.1 16.4 24.0 19.3 8.5 14.8 15.7 9.7 20.4 19.0 23.3 46.7 27.7 12.1 11.1 24.5 5.7 14.2 22.6 20.6 16.5 17.7 40.1 20.1 10.6 7.9 14.5 32.0 17.3 11.5 23.7 29.5 16.9 16.7 33.8 19.7 57.4 21.9 17.4 20.5 14.4 16.0 17.8 18.0 19.4 7.3 15.7 14.6 57.7 37.1 39.3 31.4 34.4 27.1 61.9 19.9 13.3 15.3 39.4 60.8 48.7 14.2 17.1 31.4 15.4 33.8 36.2 12.8 15.1 28.3 9.5 19.5 20.3 14.4 36.5 6.3 7.5 26.3 0.0 1.0 2.8 1.8 0.6 1.8 2.5 1.3 2.3 1.4 1.8 2.9 2.2 0.4 2.1 0.3 4.0 2.2 1.2 16.0 18.1 16.4 16.1 14.7 16.0 18.4 16.7 17.6 17.1 16.4 20.4 6.6 3.2 14.9 11.4 12.8 1.7 7.1 7.6 8.0 16.8 22.0 16.0 13.7 17.2 11.7 20.2 8.4 5.2 17.0 3.3 19.6 14.3 0.6 14.9 8.8 7.6 20.4 8.0 2.4 6.2 2.0 6.4 5.6 16.7 6.3 19.3 7.1 16.2 9.4 21.9 5.0 9.7 20.3 8.1 2.6 1.7 9.6 6.6 3.6 7.5 7.7 14.4 12.3 11.1 8.8 6.4 6.0 8.6 5.5 7.4 5.0 7.1 10.5 14.3 6.6 7.1 8.5 0.7 8.1 2.3 1.6 0.8 10.4 8.4 11.8 7.3 PAX3 "HUP2, WS1" ENSG00000135903 "Paired box 3" P23760 2 222199887-222298998 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Deafness, Disease variant, Proto-oncogene, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;salivary gland: 4.8;skeletal muscle: 3.6;skin 1: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 14.4;Late spermatids: 34.8;Melanocytes: 33.8;Skeletal myocytes: 12.8" "Cancer enriched" "Detected in some" 24 "melanoma: 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 9.0;BJ hTERT+ SV40 Large T+ RasG12V: 10.6;HBF TERT88: 8.0;RH-30: 17.5;SK-MEL-30: 29.1" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;midbrain: 1.4;pons and medulla: 1.3" "Region enhanced" "Detected in many" "midbrain: 7.7" "HPA063659, HPA069000" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA063659: AB_2685080, HPA069000: AB_2686067" "unprognostic (2.57e-2)" "unprognostic (1.48e-2)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.61e-2)" "unprognostic (3.70e-1)" "unprognostic (6.18e-2)" "unprognostic (1.41e-1)" "unprognostic (2.26e-1)" "unprognostic (9.70e-2)" 0.5 0.0 0.4 0.0 0.1 0.0 1.0 4.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.3 1.9 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 4.8 0.0 3.6 2.9 0.0 0.0 2.0 0.0 0.0 1.1 1.2 0.0 0.0 0.8 0.1 0.0 0.1 5.5 0.0 0.0 4.9 0.0 0.0 0.0 0.0 6.0 6.5 9.0 10.6 0.0 0.7 0.0 0.0 4.4 0.2 0.0 0.0 0.0 8.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 6.9 0.1 0.0 0.0 0.0 17.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 29.1 7.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 3.5 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.6 0.1 0.0 0.1 3.3 1.9 2.8 2.0 1.2 5.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.2 0.0 0.0 2.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.8 34.8 0.9 0.1 33.8 1.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.4 5.6 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 29 "B-cells: 91.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 9 "Daudi: 66.6;REH: 194.1;U-698: 87.1" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.3 0.1 0.4 14.9 0.3 9.4 0.1 0.5 0.5 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.8 0.2 0.3 0.6 0.1 0.2 0.3 39.7 1.1 6.5 0.0 0.0 0.0 0.2 0.1 4.1 0.3 0.8 0.5 1.0 0.0 3.1 0.0 6.6 0.0 0.8 18.7 1.6 0.6 1.9 2.8 0.2 0.0 36.2 1.1 0.0 0.3 0.1 0.3 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 66.6 0.1 0.0 0.1 0.2 0.1 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.1 0.3 1.9 0.3 0.4 194.1 0.4 0.3 0.0 0.0 13.2 2.9 0.1 0.7 0.0 0.0 0.0 7.5 0.2 0.0 0.2 0.1 0.0 0.2 0.1 87.1 0.0 1.5 0.1 0.7 0.0 0.1 0.0 0.1 0.1 39.0 0.0 0.0 0.1 26.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.7 0.4 0.3 0.5 0.5 0.3 0.6 1.1 6.5 4.1 0.8 1.9 0.3 0.0 0.0 0.0 0.7 91.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.3 0.0 3.1 0.0 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.0 0.1 0.0 2.7 0.4 0.0 0.1 0.0 0.1 0.0 0.8 0.1 0.6 0.2 0.2 0.0 0.0 2.0 0.0 0.0 0.3 PAX7 Hup1 ENSG00000009709 "Paired box 7" P23759 1 18630846-18748866 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 4.2;skeletal muscle: 5.7;tongue: 4.4" "Cell type enriched" "Detected in some" 284 "Skeletal myocytes: 341.4" "Group enriched" "Detected in some" 6 "breast cancer: 0.5;cervical cancer: 1.5;lung cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 1.4;CAPAN-2: 1.4;U-2 OS: 3.0" "Region enriched" "Detected in single" 17 "midbrain: 4.6" "Region enhanced" "Detected in some" "thalamus: 4.3" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.41e-4)" "unprognostic (2.07e-1)" "unprognostic (5.35e-2)" "unprognostic (3.96e-2)" "unprognostic (4.21e-1)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 3.1 4.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.2 1.3 0.3 0.1 3.1 4.2 2.2 2.4 0.4 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 341.4 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PAX8 ENSG00000125618 "Paired box 8" Q06710 2 113215997-113278921 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 267.9;thyroid gland: 565.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 246.5;Endometrial ciliated cells: 114.0;Glandular and luminal cells: 228.2;Proximal tubular cells: 128.1" "Group enriched" "Detected in many" 12 "endometrial cancer: 60.6;ovarian cancer: 63.5;renal cancer: 33.2;thyroid cancer: 122.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 7 "EFO-21: 79.7;GAMG: 50.0;RPTEC TERT1: 193.2" "Region enriched" "Detected in some" 4 "pons and medulla: 5.5" "HPA030062, CAB055097, CAB061888, HPA064554" Enhanced Enhanced Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB055097: AB_2236705, CAB061888: AB_10895719, HPA030062: AB_10603982, HPA064554: AB_2685283" "unprognostic (2.63e-3)" "unprognostic (3.80e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (7.24e-2)" "unprognostic (5.16e-5)" "unprognostic (1.56e-2)" "unprognostic (3.29e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (4.13e-2)" "unprognostic (4.00e-2)" "unprognostic (3.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.37e-1)" "unprognostic (8.93e-3)" "unprognostic (1.02e-1)" 2.0 6.0 1.4 0.6 0.9 0.5 1.7 0.1 1.1 14.5 1.7 1.8 0.6 8.8 32.9 2.2 37.5 3.6 2.1 1.0 1.9 267.9 1.2 1.6 1.7 5.2 1.3 1.7 1.0 1.4 1.4 1.9 3.0 1.1 0.9 1.5 1.9 26.1 0.5 1.8 2.4 0.8 3.7 0.8 1.4 2.4 2.3 0.5 565.5 0.3 1.0 2.1 1.0 1.9 9.4 0.8 0.4 0.0 0.4 0.2 3.0 2.6 8.0 0.7 1.2 5.7 1.6 1.7 79.7 0.6 50.0 0.1 1.6 2.6 0.7 3.9 0.0 1.5 0.7 3.4 0.9 0.0 0.0 2.3 0.3 0.6 1.9 9.9 0.1 0.0 1.3 6.2 2.5 1.8 1.0 3.8 0.5 2.2 5.5 0.0 0.6 2.1 193.2 14.4 1.5 0.0 10.4 0.1 5.6 0.0 0.0 3.5 2.7 13.8 0.5 2.6 7.2 1.2 4.6 0.6 11.9 2.0 0.0 0.7 1.0 0.0 0.1 0.6 0.4 1.3 0.4 0.3 0.9 0.5 0.7 0.4 0.2 0.6 0.4 0.3 0.2 0.4 1.4 0.9 0.1 1.1 1.0 1.9 5.2 1.3 3.0 3.7 2.3 1.9 1.3 3.2 2.0 0.7 4.1 0.6 1.9 1.8 7.4 0.6 2.0 1.4 0.9 5.7 3.4 246.5 0.0 2.4 1.6 9.5 46.9 8.5 1.6 114.0 21.8 1.4 4.8 3.0 0.8 2.9 2.4 1.6 4.1 228.2 0.0 1.0 1.1 0.3 5.2 0.0 0.8 3.2 2.0 2.6 2.1 3.9 5.0 5.6 0.0 0.0 2.0 4.0 1.0 0.5 0.2 29.2 7.4 0.4 0.5 1.6 6.3 128.1 0.6 0.9 6.6 3.6 1.7 6.2 7.3 12.5 0.9 0.8 3.1 0.4 3.7 2.2 PBRM1 "BAF180, PB1" ENSG00000163939 "Polybromo 1" Q86U86 3 52545352-52685917 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015629, HPA059373" Uncertain Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA015629: AB_1855012, HPA059373: AB_2683994" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "unprognostic (1.02e-2)" "unprognostic (9.54e-2)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (1.99e-2)" "unprognostic (4.32e-2)" "unprognostic (2.89e-3)" "unprognostic (3.06e-1)" "unprognostic (1.96e-1)" "unprognostic (1.53e-2)" "unprognostic (1.06e-1)" 21.4 12.9 6.4 20.8 11.0 24.6 16.6 18.5 8.9 21.1 13.2 17.9 15.4 22.1 16.4 22.5 19.4 16.9 18.5 6.0 11.9 11.2 18.2 17.6 22.1 10.7 9.9 29.4 12.0 14.3 8.7 20.9 11.8 18.6 18.5 20.2 13.1 17.4 15.5 17.3 14.2 25.4 8.6 18.9 16.0 14.1 10.3 42.0 26.7 22.8 22.0 20.0 12.0 19.8 32.5 20.5 71.9 35.4 34.7 35.0 50.4 44.5 29.9 49.5 43.0 23.3 21.5 78.7 6.2 51.8 40.8 21.8 63.1 33.1 59.6 85.5 34.6 74.6 38.1 18.1 49.6 62.7 54.6 33.2 37.3 55.4 35.4 38.9 48.4 60.6 43.7 41.7 50.3 11.0 103.9 18.8 43.8 22.0 34.4 53.8 45.1 40.1 20.4 62.5 48.7 53.8 52.7 12.4 41.6 43.4 23.4 35.7 56.5 46.1 34.8 40.1 54.4 30.0 51.3 73.6 28.5 49.8 46.9 9.0 4.0 9.9 3.6 2.6 3.8 2.9 3.6 4.0 4.0 5.3 5.7 3.6 2.3 3.6 8.0 8.7 3.9 1.6 6.4 11.0 18.5 8.9 6.0 11.9 10.7 9.9 11.8 8.6 10.3 19.8 49.1 41.7 61.3 95.3 44.0 40.5 35.8 28.3 43.9 45.6 40.7 30.4 61.7 30.0 39.8 23.9 47.9 36.0 67.7 36.8 19.6 37.7 39.1 61.4 54.5 47.7 35.2 82.9 76.4 46.2 36.9 39.8 42.8 46.8 29.1 61.9 33.5 47.9 53.0 30.3 84.5 35.3 28.5 61.7 47.7 17.1 34.2 65.6 48.0 80.6 67.6 29.1 49.4 87.9 135.5 49.7 29.2 58.3 76.9 37.5 18.7 18.4 58.2 44.3 26.3 54.3 69.2 48.6 35.8 43.7 51.6 50.9 50.4 45.8 39.8 37.0 PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 382.3;Excitatory neurons: 475.9;Inhibitory neurons: 405.0;Oligodendrocyte precursor cells: 327.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 93.0;NTERA-2: 111.5;SK-BR-3: 186.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003505, HPA003881, CAB018768" Supported Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: AB_675783, HPA003505: AB_1855019, HPA003881: AB_1855020" "unprognostic (2.26e-2)" "unprognostic (1.95e-1)" "unprognostic (9.09e-2)" "unprognostic (2.14e-2)" "unprognostic (5.21e-3)" "unprognostic (6.94e-3)" "unprognostic (5.95e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.30e-1)" "unprognostic (8.81e-2)" "unprognostic (1.34e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" 24.3 32.1 16.5 11.8 22.3 3.1 36.1 10.7 18.0 88.3 1.9 52.3 22.4 136.8 21.6 30.1 74.6 37.6 24.0 15.3 14.1 29.4 7.7 20.7 4.5 8.8 32.7 52.1 48.1 29.5 14.3 19.5 6.7 38.0 19.8 17.1 43.8 53.8 36.3 10.2 19.9 125.2 13.7 10.2 21.9 6.8 12.6 10.9 35.1 26.5 8.1 40.2 41.5 12.1 2.9 74.4 82.4 19.1 50.8 23.3 3.4 25.2 20.9 8.4 6.1 14.2 11.8 0.0 5.5 47.8 4.3 22.8 31.7 8.1 3.6 3.1 31.3 93.0 56.5 0.3 34.7 0.0 22.2 24.4 0.0 5.4 2.1 19.2 0.3 0.0 0.2 0.0 2.2 47.1 0.2 0.6 111.5 3.8 4.5 0.0 21.6 27.0 6.3 44.1 2.5 39.6 27.8 186.1 0.1 71.4 73.2 0.0 0.5 3.7 8.6 24.2 8.1 8.5 61.2 0.1 0.4 0.2 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 16.5 22.3 10.7 18.0 15.3 14.1 8.8 32.7 6.7 13.7 12.6 12.1 28.6 22.4 18.6 382.3 2.8 22.8 115.0 39.8 70.6 39.9 129.9 87.8 50.0 98.7 25.3 33.1 110.5 101.3 1.5 29.2 33.2 47.9 91.3 47.7 144.3 47.0 90.9 30.3 475.9 68.7 7.3 126.7 32.1 38.5 71.7 57.6 68.9 18.7 9.7 5.0 405.0 38.2 50.8 1.9 17.5 124.4 63.6 12.1 16.0 125.5 1.6 33.5 1.0 327.2 227.4 31.7 72.5 103.8 2.8 41.5 40.4 57.9 37.3 30.6 39.5 142.0 70.9 2.3 17.5 83.6 28.1 104.7 7.6 168.0 43.7 75.9 PCBP1 "hnRNP-E1, hnRNP-X, HNRPE1, HNRPX" ENSG00000169564 "Poly(rC) binding protein 1" Q15365 2 70087477-70089203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037113, HPA043803, HPA068497" Approved Enhanced "Nuclear speckles,Cytoplasmic bodies" No No 1600000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Cytoplasmic bodies" "CAB037113: AB_1840915, HPA043803: AB_2678676, HPA068497: AB_2685996" "unprognostic (1.63e-1)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (7.08e-2)" "unprognostic (5.37e-1)" "unprognostic (1.63e-2)" "unprognostic (8.33e-2)" "unprognostic (9.94e-3)" "unprognostic (2.01e-1)" "unprognostic (2.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-1)" "unprognostic (5.90e-2)" 278.3 276.3 145.5 199.8 155.0 390.0 240.4 168.5 203.5 209.3 159.1 259.9 172.8 253.9 142.6 278.4 193.8 134.9 223.2 142.1 155.6 218.1 304.3 233.6 227.1 163.7 146.9 186.0 249.9 174.6 140.2 194.8 159.2 143.9 125.8 90.5 185.0 139.5 782.3 216.6 203.1 172.4 163.8 241.3 214.5 95.2 150.4 301.0 170.8 308.3 209.6 233.8 206.0 190.9 384.9 387.5 327.1 257.5 345.1 262.4 525.9 280.5 257.2 272.0 227.0 453.0 250.6 522.9 140.9 320.7 293.7 334.7 388.4 408.6 276.5 376.2 299.9 419.2 219.5 701.3 388.0 350.8 385.8 230.3 261.6 224.5 310.5 203.4 350.7 138.9 437.2 375.6 346.2 475.7 454.7 524.7 331.5 361.1 253.2 362.9 358.0 527.1 375.5 389.6 309.7 249.1 230.3 465.8 342.1 229.8 277.6 314.2 325.1 253.5 317.6 217.6 359.4 495.7 551.2 531.7 268.6 480.4 319.5 42.6 89.7 141.5 80.3 92.5 73.8 41.1 62.1 69.3 82.9 36.4 62.8 71.2 138.2 95.4 80.5 58.9 81.7 100.5 145.5 155.0 168.5 203.5 142.1 155.6 163.7 146.9 159.2 163.8 150.4 190.9 241.0 153.8 132.7 27.4 312.7 484.0 296.0 192.1 196.9 64.9 270.8 212.6 0.6 208.8 134.5 196.8 22.9 372.4 208.7 401.7 272.0 196.0 34.4 187.6 220.8 242.8 178.6 485.3 19.1 199.2 470.1 196.9 227.9 284.8 114.2 129.6 227.0 392.7 385.7 58.9 18.0 239.8 138.4 509.2 795.9 34.4 186.1 382.4 300.6 30.0 422.9 122.3 347.1 14.1 49.1 211.7 311.7 186.5 357.1 278.5 338.4 481.0 128.6 56.1 170.9 222.9 241.9 131.0 65.5 267.0 545.8 703.4 291.2 148.4 232.9 366.6 PCM1 PTC4 ENSG00000078674 "Pericentriolar material 1" Q15154 8 17922840-18027975 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 528.5;Spermatocytes: 569.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023370, HPA023374, CAB058695" Enhanced Supported "Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centriolar satellite" Cytosol "CAB058695: AB_2665588, HPA023370: AB_1855072, HPA023374: AB_1855073" "unprognostic (1.52e-2)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (3.35e-2)" "unprognostic (9.52e-2)" "unprognostic (1.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.74e-3)" "unprognostic (1.09e-1)" "unprognostic (2.26e-1)" "unprognostic (2.84e-1)" "unprognostic (2.83e-1)" "unprognostic (1.76e-2)" "unprognostic (2.16e-1)" "unprognostic (4.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.45e-1)" 29.5 31.3 32.9 28.1 39.7 52.2 43.1 42.7 37.0 39.3 39.9 37.3 21.8 39.3 41.6 28.1 44.1 30.7 38.6 31.7 35.0 33.0 39.2 33.6 41.5 35.5 34.2 47.0 39.9 52.6 31.0 35.2 37.2 33.5 27.4 76.6 35.1 32.2 105.3 30.4 29.5 30.6 32.8 33.4 27.9 154.2 35.8 56.9 49.0 84.9 37.3 31.0 26.2 47.0 64.0 66.8 100.5 133.4 55.2 57.0 51.7 52.6 64.4 54.9 61.3 45.4 37.0 83.0 35.3 52.8 47.2 45.0 64.8 48.3 93.0 27.6 25.1 142.7 46.2 93.1 61.6 63.7 35.1 50.3 50.6 63.9 70.3 47.9 64.1 84.9 98.4 62.6 67.9 32.0 136.8 103.3 82.7 52.8 19.1 81.0 90.1 30.0 45.3 87.1 76.6 57.6 56.5 30.5 82.1 42.8 48.2 91.0 57.8 49.6 40.5 61.3 45.0 26.6 62.9 72.5 41.8 68.3 52.0 31.5 7.2 18.7 13.0 4.6 13.5 13.0 11.6 15.1 7.3 13.1 12.9 13.2 7.6 13.9 10.0 17.8 13.1 5.6 32.9 39.7 42.7 37.0 31.7 35.0 35.5 34.2 37.2 32.8 35.8 47.0 91.6 128.2 154.9 187.7 109.3 33.8 66.3 44.4 75.7 196.1 74.1 72.0 249.4 62.9 117.2 86.5 350.3 50.9 145.9 33.6 29.4 73.0 528.5 275.2 130.4 86.5 71.2 115.5 219.9 59.0 33.6 100.4 55.0 132.5 142.1 103.9 64.6 50.8 43.3 129.5 211.8 45.7 61.1 61.3 39.7 301.3 92.2 83.6 55.2 162.1 82.8 145.8 132.8 208.6 243.1 58.9 36.0 97.8 84.7 45.8 45.6 25.9 282.1 234.9 124.9 173.8 92.7 569.3 177.1 65.4 38.2 60.5 122.5 92.1 50.6 47.2 PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 383.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000148, HPA030521, HPA030522, HPA030523" Enhanced Enhanced Nucleoplasm No Yes 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000148: AB_628110, HPA030521: AB_10600218, HPA030522: AB_10602096, HPA030523: AB_10602199" "unprognostic (5.21e-2)" "prognostic favorable (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-1)" "unprognostic (5.60e-3)" "prognostic unfavorable (2.61e-4)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.89e-2)" "unprognostic (1.01e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.03e-6)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (7.11e-3)" "unprognostic (7.46e-2)" 31.2 47.2 23.2 85.2 26.0 383.2 51.0 26.8 29.7 41.5 26.8 89.0 70.7 38.1 30.9 81.2 39.1 34.8 30.6 23.0 24.4 43.7 55.3 37.5 168.8 25.1 24.0 37.7 32.8 42.4 25.1 69.8 26.0 32.2 93.7 94.1 40.3 38.3 27.9 62.8 72.9 47.9 26.8 54.0 53.9 62.3 23.3 219.9 42.0 26.8 137.3 51.0 42.3 30.0 769.1 591.4 585.0 253.7 136.1 126.6 409.5 491.6 288.3 453.7 640.0 465.3 594.2 773.4 155.7 177.5 395.2 558.8 350.7 594.4 413.2 231.7 386.8 543.7 207.8 1098.3 57.8 753.7 233.0 92.6 138.2 387.2 91.7 95.3 263.3 503.6 493.9 631.2 449.7 278.3 1450.6 829.3 439.9 592.0 322.9 787.9 514.1 622.5 208.5 441.1 500.8 339.4 345.1 524.6 351.9 213.9 371.2 378.0 177.2 324.3 373.3 461.5 572.0 317.2 981.6 1313.9 145.9 707.4 426.2 5.0 23.2 18.5 36.5 23.3 45.7 33.5 45.7 37.1 32.6 29.2 41.6 37.3 7.7 43.6 24.7 29.9 48.1 36.7 23.2 26.0 26.8 29.7 23.0 24.4 25.1 24.0 26.0 26.8 23.3 30.0 32.4 44.8 26.0 2.9 40.6 67.7 44.4 121.4 44.3 42.1 27.5 45.2 14.5 21.5 60.5 58.8 27.1 171.5 44.3 42.9 60.7 51.6 176.0 30.2 21.4 34.8 19.9 189.0 4.3 39.6 175.6 38.7 21.9 27.7 22.7 53.1 29.6 27.1 96.7 32.0 5.9 53.9 75.3 24.2 33.4 109.1 36.1 32.7 37.4 3.7 47.6 74.0 23.7 4.0 13.5 28.3 20.3 40.3 56.6 23.3 33.3 46.1 44.1 97.1 52.6 29.2 46.1 149.1 101.1 65.5 49.7 66.4 48.6 29.6 84.5 40.4 PDAP1 "HASPP28, PAP, PAP1" ENSG00000106244 "PDGFA associated protein 1" Q13442 7 99392048-99408597 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021103, HPA050294, HPA060836" Approved Enhanced "Plasma membrane,Cytosol" NA NA 410000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB021103: AB_10057973, HPA050294: AB_2681077, HPA060836: AB_2684374" "unprognostic (2.27e-1)" "unprognostic (1.45e-1)" "unprognostic (3.87e-2)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.65e-2)" "unprognostic (2.63e-1)" "unprognostic (3.35e-2)" "unprognostic (1.45e-2)" "unprognostic (3.51e-2)" "unprognostic (1.79e-1)" "unprognostic (3.49e-1)" "unprognostic (2.97e-2)" 25.7 29.6 35.8 22.6 36.2 23.2 24.4 36.5 39.3 26.2 34.1 32.4 17.9 26.9 17.5 37.2 22.6 11.9 40.2 34.4 36.1 28.5 31.3 24.0 18.9 37.3 37.9 25.7 26.6 22.5 21.9 19.2 37.4 26.0 18.0 22.9 26.2 20.9 105.0 27.9 23.3 21.1 37.6 23.8 26.3 19.7 37.0 25.5 24.3 59.7 22.4 29.3 26.4 36.6 96.9 82.4 54.6 71.0 41.5 43.2 34.7 76.7 44.9 61.6 51.8 83.9 47.4 41.3 67.2 74.7 78.4 50.2 66.3 78.4 60.5 59.8 74.4 43.6 80.8 74.1 60.8 80.1 40.5 45.6 58.5 68.1 110.3 56.3 62.7 67.5 103.0 75.6 61.4 200.3 110.4 111.2 68.7 98.1 88.3 50.5 54.3 73.6 63.6 73.0 54.8 110.6 58.0 92.4 43.4 61.3 41.1 42.5 57.6 83.6 91.4 100.8 123.6 71.4 87.5 91.0 67.7 72.2 89.1 13.4 12.1 12.5 15.4 16.6 13.9 15.7 14.2 11.2 10.2 14.9 9.8 13.2 31.6 28.0 15.6 21.1 20.9 6.6 35.8 36.2 36.5 39.3 34.4 36.1 37.3 37.9 37.4 37.6 37.0 36.6 82.9 86.6 94.7 6.2 73.6 62.2 110.6 104.6 57.5 97.4 84.3 76.6 63.6 72.9 86.7 42.3 33.3 213.1 84.7 101.6 168.3 176.1 60.3 91.3 118.6 99.1 117.9 151.7 10.1 171.0 223.0 87.4 59.7 88.3 72.2 83.4 61.8 80.8 114.9 77.4 11.6 116.5 75.3 38.3 63.3 78.3 83.6 66.1 103.2 5.6 102.1 166.4 119.4 8.0 17.4 177.4 92.2 92.2 102.5 184.3 100.0 134.5 96.8 101.0 52.6 85.6 127.2 132.5 123.0 131.9 65.6 184.4 79.5 115.2 114.0 122.5 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDCD2L MGC13096 ENSG00000126249 "Programmed cell death 2 like" Q9BRP1 19 34404399-34426168 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 35.7;Spermatogonia: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052181 Approved Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA052181: AB_2681751" "unprognostic (5.39e-2)" "unprognostic (3.48e-1)" "unprognostic (1.51e-1)" "unprognostic (6.99e-2)" "unprognostic (1.07e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.81e-4)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (8.78e-2)" "unprognostic (1.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.75e-1)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "unprognostic (5.98e-2)" 4.2 5.6 5.0 2.7 5.3 3.1 4.1 4.8 5.8 4.3 4.2 5.3 2.6 5.0 2.9 5.3 5.0 2.1 7.5 5.0 5.6 3.5 5.5 2.9 4.7 4.5 4.7 4.4 8.3 2.2 5.8 2.5 4.9 3.4 3.4 1.1 5.5 3.8 24.7 4.7 4.0 3.1 4.7 4.8 6.5 14.4 5.4 2.9 3.1 9.1 4.8 4.8 3.9 5.7 21.6 35.9 4.4 8.7 2.0 4.2 13.8 6.8 4.9 11.1 11.1 33.6 15.1 17.7 28.8 3.9 11.6 7.4 17.4 14.9 11.7 26.1 36.6 17.4 5.7 26.8 14.5 34.0 9.8 5.1 12.9 6.5 21.2 4.6 11.3 28.0 35.1 9.0 9.6 27.3 13.4 12.4 16.0 47.3 34.4 19.2 8.2 25.1 14.1 12.1 25.8 9.2 0.7 21.4 12.5 7.3 9.3 13.9 6.0 7.3 9.0 8.6 23.4 20.1 32.8 31.4 9.1 29.8 6.3 0.0 3.3 0.0 9.1 5.3 12.9 12.7 8.9 9.0 6.8 10.1 13.1 9.9 0.7 12.5 3.4 23.6 11.7 5.7 5.0 5.3 4.8 5.8 5.0 5.6 4.5 4.7 4.9 4.7 5.4 5.7 5.5 3.2 4.8 3.6 7.6 8.2 15.0 7.6 10.2 4.3 4.8 7.4 5.1 5.7 4.8 3.7 2.1 8.1 12.0 1.7 7.9 13.3 27.4 6.3 4.3 4.9 12.1 4.6 4.2 15.3 7.0 5.1 9.2 2.7 4.5 5.6 5.0 5.1 7.5 1.7 4.3 5.0 2.0 3.3 3.7 3.9 5.3 4.1 3.6 2.8 7.1 4.8 9.2 4.0 3.4 13.1 5.0 6.8 8.2 27.6 1.1 10.2 6.1 2.4 0.0 6.1 12.6 35.7 42.9 7.5 10.7 1.8 5.4 8.2 7.7 9.6 PDE4DIP "CMYA2, KIAA0454, KIAA0477, MMGL" ENSG00000178104 "Phosphodiesterase 4D interacting protein" Q5VU43 1 148808181-149048286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 729.5;skeletal muscle: 2164.0;tongue: 1379.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 702.6;Rod photoreceptor cells: 272.3;Syncytiotrophoblasts: 309.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 289.6;ASC TERT1: 233.8;K-562: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012678 Supported "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA012678: AB_1855123" "unprognostic (2.14e-1)" "unprognostic (3.27e-1)" "unprognostic (5.31e-2)" "unprognostic (6.73e-2)" "unprognostic (7.82e-2)" "unprognostic (1.16e-2)" "unprognostic (2.17e-1)" "unprognostic (9.72e-2)" "unprognostic (7.65e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-2)" "unprognostic (5.08e-2)" "unprognostic (1.70e-3)" "unprognostic (1.82e-1)" "unprognostic (4.14e-2)" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" 32.9 16.9 103.0 20.9 82.9 15.8 22.3 142.7 106.1 28.0 32.4 22.5 24.2 17.4 73.5 37.9 19.8 19.5 729.5 115.5 118.5 42.0 63.5 36.1 21.7 102.2 95.6 8.6 21.4 84.6 53.1 68.5 109.7 29.2 25.4 173.3 34.9 22.9 2164.0 26.1 29.4 18.8 96.8 17.2 29.7 9.2 139.9 12.1 16.9 1379.7 23.2 24.0 17.1 114.9 39.2 7.5 10.6 11.6 289.6 233.8 60.7 45.2 42.3 42.7 55.7 35.5 24.1 19.8 13.7 64.5 121.3 19.8 25.7 31.5 72.1 14.7 36.8 10.0 16.2 14.2 76.2 8.8 10.2 167.5 61.9 181.7 97.8 96.9 17.1 16.3 222.1 45.0 76.8 66.2 6.9 5.4 37.1 32.3 15.9 14.6 26.5 7.7 25.4 39.9 50.1 4.7 44.1 123.4 36.1 44.7 37.5 11.7 22.9 49.3 11.2 124.7 100.9 19.9 29.6 29.1 200.6 8.0 30.2 10.6 5.7 4.5 5.3 6.1 5.5 12.0 10.6 7.1 7.0 11.0 8.1 4.5 1.3 4.9 2.1 3.0 14.4 4.8 103.0 82.9 142.7 106.1 115.5 118.5 102.2 95.6 109.7 96.8 139.9 114.9 5.7 51.3 45.1 81.3 24.0 28.8 9.9 19.8 23.3 71.0 16.1 11.3 702.6 24.3 45.4 69.9 114.7 184.6 9.5 24.0 62.6 13.1 38.9 41.1 14.2 15.7 43.2 7.4 85.8 7.1 148.3 54.2 20.4 27.0 13.9 6.1 5.3 80.8 45.0 33.7 81.1 32.0 20.3 46.1 90.4 50.0 10.5 68.7 55.2 6.5 21.5 45.7 14.4 65.9 41.5 4.5 25.1 9.8 37.5 4.1 48.8 20.7 88.0 272.3 32.9 131.2 40.1 8.7 15.9 14.6 16.3 309.2 24.0 4.2 24.2 4.3 PDGFA "PDGF-A, PDGF1" ENSG00000197461 "Platelet derived growth factor subunit A" P04085 7 497258-520296 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 95.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 89.8;Breast myoepithelial cells: 154.9;Paneth cells: 97.0;Smooth muscle cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 11.3" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "WM-115: 311.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005579, HPA065024" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 580000 "Cluster 42: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "CAB005579: AB_2161916, HPA065024: " "unprognostic (2.22e-1)" "unprognostic (2.83e-1)" "unprognostic (1.17e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.75e-4)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.63e-3)" "unprognostic (4.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.85e-1)" "unprognostic (8.26e-2)" "unprognostic (1.07e-2)" "unprognostic (5.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (8.67e-4)" 15.4 8.5 29.3 7.9 36.8 1.7 17.0 36.6 32.4 18.1 20.5 29.2 20.2 26.1 11.2 9.6 21.2 11.4 21.1 27.0 27.5 22.2 8.5 24.9 3.5 46.4 37.5 7.7 71.6 6.6 10.2 26.8 40.7 23.3 14.8 5.2 20.3 11.2 95.2 12.5 25.9 10.2 35.8 16.3 32.1 4.5 36.5 6.6 10.0 15.1 2.4 17.8 15.9 58.8 22.9 15.3 1.5 21.6 4.1 0.7 50.7 5.0 2.9 6.4 4.4 23.8 25.3 0.6 8.7 4.3 2.9 56.6 1.5 69.0 3.4 12.9 2.3 0.3 13.3 8.7 26.9 2.4 2.2 3.0 26.8 3.3 21.3 8.5 12.5 1.3 2.3 3.1 15.8 28.7 3.5 5.0 40.1 8.9 3.3 11.6 1.5 2.5 9.0 5.3 2.1 1.8 76.5 4.2 13.3 47.5 10.7 2.6 37.3 13.6 37.8 8.0 31.0 0.9 1.4 0.8 12.3 7.1 311.4 11.3 1.6 2.4 1.6 1.9 2.2 1.9 1.6 1.5 1.5 1.8 1.9 2.0 4.9 3.4 3.3 2.1 1.8 2.1 29.3 36.8 36.6 32.4 27.0 27.5 46.4 37.5 40.7 35.8 36.5 58.8 15.2 89.8 11.9 11.1 1.5 28.0 20.2 12.1 59.7 15.7 12.7 154.9 29.9 15.7 11.0 14.7 8.4 8.8 1.7 76.9 5.9 15.8 0.3 49.0 4.2 19.4 13.1 0.0 7.7 53.3 5.4 12.3 41.8 35.7 10.8 18.1 21.0 1.0 2.0 32.0 5.9 40.5 2.0 1.3 10.4 0.1 2.1 14.8 14.2 6.5 1.5 0.7 1.0 5.0 27.5 72.6 97.0 6.4 4.4 29.4 47.2 8.5 4.5 2.1 39.5 48.9 110.3 0.5 1.8 9.4 9.8 2.9 3.9 0.2 32.1 18.2 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 1288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC diff: 1350.1;ASC TERT1: 462.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" 171.2 25.1 25.4 27.5 27.2 0.7 106.3 20.5 33.3 155.9 43.5 41.6 11.9 101.1 24.2 24.1 89.6 124.5 75.7 22.1 23.2 49.7 13.4 98.3 27.5 22.1 24.6 105.5 20.8 21.9 23.0 113.3 22.8 56.2 14.1 6.3 34.5 43.3 38.1 65.0 37.9 68.9 19.4 41.4 27.9 18.4 27.7 8.7 66.5 44.1 13.8 58.3 98.6 21.6 0.1 0.3 8.3 0.4 1350.1 462.7 3.0 48.9 202.3 33.5 56.4 5.4 0.0 0.0 6.4 142.0 19.0 0.1 0.1 0.4 15.8 0.0 0.0 0.1 3.3 3.5 190.7 0.0 0.4 210.0 0.0 46.3 0.6 106.6 0.1 0.1 0.1 5.5 5.5 0.0 0.1 0.6 9.0 0.2 0.2 3.7 2.5 0.2 0.0 0.0 0.1 24.8 0.5 0.1 0.0 38.2 0.1 0.6 0.4 53.7 17.2 23.1 2.8 0.4 0.0 0.3 33.4 0.1 1.5 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.2 25.4 27.2 20.5 33.3 22.1 23.2 22.1 24.6 22.8 19.4 27.7 21.6 50.8 0.0 1.1 81.9 0.5 24.0 0.5 0.0 2.2 6.6 1.4 3.3 17.3 1.5 0.0 1.8 4.2 0.6 6.0 0.3 0.0 0.8 1.6 2.8 99.5 32.2 0.0 0.0 7.9 0.0 1.1 123.5 2.0 2.3 0.0 2.5 6.4 1.9 1.5 0.0 1.3 0.7 0.0 0.0 35.6 10.9 165.3 3.1 24.9 45.0 0.7 50.7 23.7 10.1 3.3 0.1 0.1 203.8 2.3 0.7 0.3 0.1 0.7 2.9 1288.5 6.6 288.3 1.9 1.6 0.8 15.3 0.8 4.8 4.0 0.4 1.1 PDSS2 "bA59I9.3, C6orf210, COQ1B" ENSG00000164494 "Decaprenyl diphosphate synthase subunit 2" Q86YH6 6 107152562-107459564 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 82.4;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029685, HPA029686" Approved Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA029685: AB_10600219, HPA029686: AB_10602309" "prognostic unfavorable (1.34e-5)" "unprognostic (1.44e-1)" "prognostic favorable (5.74e-5)" "unprognostic (5.76e-2)" "unprognostic (1.42e-1)" "unprognostic (3.30e-2)" "unprognostic (3.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (9.38e-2)" "unprognostic (2.19e-1)" "prognostic favorable (3.75e-7)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" 7.9 17.9 4.6 6.3 5.2 9.0 8.1 6.1 5.7 9.2 6.8 12.4 9.3 6.8 6.5 8.6 8.6 8.7 13.9 4.6 5.2 21.6 27.1 8.0 7.6 4.9 4.7 9.1 8.4 13.2 8.5 6.8 5.0 14.6 13.2 6.0 15.3 7.4 12.5 6.3 9.6 8.5 4.7 6.7 9.6 7.7 5.3 8.1 13.3 13.7 7.1 7.6 6.1 6.1 7.6 10.0 8.3 13.2 14.2 18.0 19.2 13.1 16.5 12.4 11.8 10.0 10.8 14.4 11.7 14.7 13.1 10.2 20.3 16.5 16.7 9.1 9.8 14.4 11.4 16.9 15.0 18.5 11.1 13.5 19.1 19.5 15.3 10.8 13.1 16.5 20.7 19.0 12.2 9.3 5.4 19.7 5.3 17.3 12.7 9.7 7.4 11.7 15.2 10.2 8.2 7.1 9.0 15.4 19.7 9.0 12.7 22.3 8.3 8.8 5.2 12.4 11.4 5.3 6.8 11.3 16.3 27.4 16.3 3.2 5.1 2.8 3.7 5.9 5.9 4.7 3.8 4.7 7.0 5.5 5.0 4.8 0.6 3.6 9.9 3.3 5.5 3.4 4.6 5.2 6.1 5.7 4.6 5.2 4.9 4.7 5.0 4.7 5.3 6.1 11.4 16.0 19.1 64.9 12.3 4.2 13.8 11.7 13.6 8.2 9.7 8.3 17.4 12.8 13.9 14.7 2.1 26.9 8.3 15.1 35.2 12.7 37.3 16.3 9.3 8.4 10.3 8.0 53.5 14.5 17.3 9.5 8.2 10.9 14.0 11.9 7.5 32.6 11.8 6.7 67.3 15.3 14.2 9.8 5.1 12.7 5.3 10.2 7.2 82.4 8.5 11.8 6.2 72.9 74.5 13.7 14.4 9.4 13.0 12.2 14.2 40.8 21.0 11.5 26.3 8.7 7.9 21.7 11.5 14.3 5.8 11.9 9.8 13.4 17.0 12.5 PDZD4 "FLJ34125, KIAA1444, LNX5, LU1, PDZK4, PDZRN4L" ENSG00000067840 "PDZ domain containing 4" Q76G19 X 153802166-153830565 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 150.1" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Bipolar cells: 18.0;dendritic cells: 14.0;Excitatory neurons: 11.0;NK-cells: 26.8;Rod photoreceptor cells: 14.1" "Group enriched" "Detected in many" 4 "glioma: 20.1;testis cancer: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 24.4;NTERA-2: 12.4;RH-30: 17.3;SCLC-21H: 29.5;SH-SY5Y: 28.7;U-2 OS: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003878 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "HPA003878: AB_2162807" "unprognostic (9.18e-3)" "unprognostic (1.25e-1)" "unprognostic (1.11e-4)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (1.85e-2)" "unprognostic (1.92e-3)" "unprognostic (2.17e-1)" "unprognostic (2.32e-3)" "unprognostic (5.90e-2)" "prognostic favorable (2.96e-5)" "unprognostic (2.27e-1)" "unprognostic (2.54e-4)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.83e-2)" "unprognostic (2.87e-2)" 3.7 5.0 98.2 1.9 102.8 2.1 3.4 76.6 150.1 9.5 42.3 23.4 1.6 11.9 1.2 3.8 13.9 2.0 6.1 132.0 46.9 3.9 2.6 4.8 2.0 57.6 48.0 2.7 2.3 2.8 44.1 0.1 59.5 10.4 1.3 14.8 4.1 9.8 3.3 4.3 5.9 4.3 38.2 14.0 7.6 6.0 46.7 1.1 3.5 1.3 0.6 10.0 9.2 89.8 0.0 1.6 24.4 6.4 0.0 0.1 0.0 0.7 0.0 0.7 0.8 0.6 0.0 0.0 0.3 0.0 7.9 0.1 4.5 0.0 0.1 0.0 0.8 0.0 1.9 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.1 0.3 5.0 0.2 0.9 12.4 0.0 0.3 0.1 17.3 0.0 0.0 0.1 29.5 28.7 1.3 0.0 9.2 8.2 2.8 0.3 0.0 0.0 14.1 0.3 1.8 0.0 0.1 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.2 98.2 102.8 76.6 150.1 132.0 46.9 57.6 48.0 59.5 38.2 46.7 89.8 1.8 0.0 0.0 12.1 0.1 0.3 0.0 0.0 0.6 18.0 0.1 2.4 3.7 0.0 1.3 0.0 6.2 0.0 14.0 0.0 0.0 0.0 0.1 0.2 1.5 3.5 1.8 0.8 11.0 0.2 0.0 0.8 0.5 0.1 1.3 0.2 4.6 0.1 0.0 1.7 8.6 0.0 0.0 1.0 0.0 0.2 0.6 0.1 3.6 4.7 0.2 3.9 26.8 5.5 0.7 0.3 0.0 3.8 3.6 0.2 0.0 0.0 4.4 14.1 0.0 1.7 2.1 0.3 4.1 0.5 0.9 0.0 4.1 0.0 0.0 0.2 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PER1 "PER, RIGUI" ENSG00000179094 "Period circadian regulator 1" O15534 17 8140472-8156506 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HBEC3-KT: 49.8;hTCEpi: 56.6;hTERT-HME1: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047947, HPA067064" Supported Nucleoplasm,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA047947: AB_2680219, HPA067064: AB_2685774" "unprognostic (7.64e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.54e-2)" "unprognostic (1.20e-1)" "unprognostic (2.59e-1)" "unprognostic (9.44e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.28e-2)" "unprognostic (6.67e-2)" "unprognostic (6.21e-3)" "unprognostic (6.87e-2)" "unprognostic (4.68e-2)" "unprognostic (7.09e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.08e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-2)" 128.3 73.3 17.6 36.6 19.1 53.3 113.2 25.5 27.3 85.1 25.9 99.2 10.4 63.9 6.2 61.9 101.8 36.6 88.2 18.9 21.4 56.2 73.5 95.5 18.3 19.4 20.6 168.5 103.7 49.5 103.3 20.5 17.7 83.9 11.7 22.0 62.5 27.9 211.8 182.2 58.0 30.6 16.1 54.6 82.5 35.8 18.0 12.8 100.1 67.3 11.5 81.0 90.6 25.7 2.2 8.2 9.4 13.4 29.8 21.7 5.2 3.4 5.9 4.1 4.8 8.3 5.4 15.6 2.5 4.7 4.4 6.7 9.4 49.8 2.9 4.9 11.7 8.4 18.5 2.6 40.7 3.3 11.9 33.8 56.6 7.0 54.9 5.4 9.0 11.9 10.9 21.0 7.5 7.6 9.6 6.8 7.9 2.6 5.4 13.2 5.3 8.3 9.7 1.8 4.0 9.9 6.9 7.9 6.6 3.8 5.8 2.5 15.5 4.7 8.7 1.8 2.8 12.7 5.1 5.3 6.3 4.1 3.3 0.0 1.2 0.6 0.6 0.9 0.7 0.3 0.5 0.4 1.8 0.6 0.5 0.3 1.2 0.2 0.4 0.2 0.4 0.5 17.6 19.1 25.5 27.3 18.9 21.4 19.4 20.6 17.7 16.1 18.0 25.7 88.8 54.5 78.5 24.8 47.6 53.2 38.9 31.5 118.9 37.7 39.2 37.5 24.4 51.5 37.7 27.6 98.0 5.9 63.9 16.8 5.9 6.5 28.2 48.3 23.6 39.4 50.2 50.9 18.7 4.0 4.0 50.5 60.1 54.4 70.2 11.9 40.7 48.8 19.7 20.2 9.9 22.9 16.2 59.2 70.1 52.4 41.0 91.5 48.0 15.0 12.1 40.0 3.1 8.0 5.6 8.5 21.7 33.8 55.4 34.4 38.9 6.3 48.7 49.2 32.9 89.3 47.1 6.6 10.0 63.0 59.8 13.5 84.4 12.8 16.4 19.9 PF4 "CXCL4, SCYB4" ENSG00000163737 "Platelet factor 4" P02776 4 73980811-73982027 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 66.5;lymphoid tissue: 31.5" "Cell type enriched" "Detected in some" 23 "Macrophages: 1360.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.4" "Region enriched" "Detected in single" 5 "cerebral cortex: 2.2" "Group enriched" "Detected in many" 12 "basophil: 85.2;neutrophil: 43.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 85.2" "Cell line enriched" "Detected in some" 10 "HEL: 29.8" "CAB026008, HPA052485" Enhanced "Secreted to blood" NA NA 7700000 "Cluster 34: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "CAB026008: , HPA052485: AB_2681847" "unprognostic (4.14e-4)" "unprognostic (1.00e-2)" "unprognostic (2.49e-1)" "unprognostic (1.96e-4)" "unprognostic (7.58e-2)" "unprognostic (1.42e-1)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (9.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.03e-2)" "unprognostic (9.54e-5)" "unprognostic (2.55e-1)" "unprognostic (8.77e-2)" "unprognostic (9.69e-2)" "unprognostic (4.81e-2)" 0.8 0.2 0.1 0.7 0.3 66.5 0.3 0.1 2.2 0.1 0.7 1.0 0.0 0.1 0.0 0.1 0.3 0.7 0.9 0.1 0.1 0.6 2.2 10.5 0.3 0.3 0.2 0.1 0.3 0.0 0.3 3.0 0.3 0.1 0.8 0.0 0.4 0.1 1.0 0.0 0.2 0.1 0.4 31.5 0.9 0.1 0.2 0.0 0.6 2.5 0.0 0.1 0.1 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 29.8 0.0 0.0 1.5 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.2 3.8 1.4 0.8 1.2 0.8 0.0 0.2 0.0 1.5 0.7 0.7 0.3 43.0 0.1 3.9 5.4 0.6 148.4 0.1 0.3 0.1 2.2 0.1 0.1 0.3 0.2 0.3 0.4 0.2 0.3 0.7 0.0 0.0 0.0 10.8 0.0 0.2 0.4 0.0 0.0 0.1 0.3 0.0 2.8 1.5 1.8 0.0 0.0 4.1 5.3 0.0 6.0 0.0 0.0 0.0 7.1 13.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 24.7 0.2 0.3 0.0 0.0 1.8 0.0 9.5 0.0 0.1 0.0 1360.7 0.0 0.0 59.0 0.0 57.7 0.0 0.0 7.6 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.4 0.0 0.0 0.3 5.8 0.0 7.4 0.2 PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "stomach 1: 59821.1" "Group enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 5737.5;Pancreatic endocrine cells: 1449.1" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 253.1;OE19: 152.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" 19.4 7.0 0.0 0.3 0.1 0.2 6.6 1.2 0.5 6.7 0.0 26.4 1327.3 2.8 0.9 85.5 9.2 2.3 6.2 0.1 0.0 4.9 11.0 378.8 0.3 0.0 0.0 3.9 136.3 0.0 7.4 2.8 0.0 83.9 0.3 0.1 4.6 437.7 2.5 3.4 3.2 0.0 0.0 7.7 59821.1 4.2 0.0 0.1 2.2 0.0 0.3 3.8 4.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.1 0.0 0.0 18.4 0.0 0.0 0.6 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 253.1 0.0 0.3 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.9 5.7 152.2 0.0 2.9 0.0 6.2 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.8 0.0 0.0 3.7 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.6 335.2 0.0 4.4 0.4 2.8 0.0 0.0 0.0 0.3 0.8 0.3 87.2 5.0 0.0 0.0 1.2 0.0 0.3 0.0 4.6 0.0 0.4 0.0 1.1 0.0 0.0 0.3 131.2 1.5 0.9 5737.5 0.1 10.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 1.7 0.0 0.0 2.0 0.0 0.0 0.0 0.1 1449.1 2.1 0.0 2.4 85.2 0.1 0.2 3.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 4.1 2.6 0.0 0.2 4.2 PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 50.5;thyroid gland: 52.5" "Group enriched" "Detected in many" 11 "Extravillous trophoblasts: 1604.4;Syncytiotrophoblasts: 2122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "BEWO: 422.4;HUVEC TERT2: 199.1" "Low region specificity" "Detected in all" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" No No 20800 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Mitochondria, Cytosol" "HPA041624: AB_10794522" "unprognostic (1.67e-2)" "unprognostic (4.62e-2)" "unprognostic (9.25e-3)" "unprognostic (1.34e-3)" "unprognostic (8.67e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (4.45e-1)" "unprognostic (1.45e-2)" "unprognostic (3.51e-3)" "prognostic unfavorable (1.33e-6)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (1.14e-1)" 11.8 4.9 7.4 7.8 7.6 0.1 11.3 7.3 11.7 22.4 20.2 7.0 2.4 7.6 1.4 10.0 21.8 5.9 18.8 8.7 20.6 8.1 6.0 7.2 6.4 9.5 15.7 6.4 4.9 8.4 5.5 50.5 9.3 19.3 2.0 1.2 10.5 10.3 9.9 15.7 12.5 7.8 7.0 3.3 4.8 3.2 8.6 3.9 52.5 5.9 3.3 13.6 14.8 7.8 1.4 1.5 1.3 1.3 2.0 0.2 422.4 4.0 3.6 1.8 2.2 10.9 0.6 0.3 9.1 2.8 0.2 0.5 1.8 19.2 1.6 0.2 2.4 0.0 0.1 11.3 1.5 0.2 11.0 4.7 4.5 7.5 1.8 0.5 199.1 0.0 0.0 0.1 55.6 0.9 0.0 0.5 2.1 0.1 3.4 0.2 51.3 0.0 0.5 1.0 31.0 17.0 0.0 0.8 7.7 25.0 0.1 0.5 40.6 0.3 10.2 0.1 17.0 0.4 0.2 0.7 6.3 0.5 0.5 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 7.4 7.6 7.3 11.7 8.7 20.6 9.5 15.7 9.3 7.0 8.6 7.8 32.4 9.6 4.6 1.0 1.0 24.6 10.3 111.4 34.7 1.3 8.9 16.0 3.6 0.0 26.0 0.0 14.6 83.8 2.4 2.0 0.0 2.7 0.1 1.1 3.3 169.4 7.1 2.7 0.1 0.5 1604.4 30.8 1.1 0.8 6.3 0.2 5.3 0.3 37.4 0.0 0.2 2.1 18.3 0.6 8.9 0.8 13.1 2.1 21.4 0.0 0.0 1.9 0.0 0.0 0.2 0.5 1.2 19.5 0.2 3.2 0.6 1.1 12.1 7.8 105.2 7.1 86.4 0.2 6.8 8.1 19.6 2122.6 3.0 3.0 2.3 5.8 PGR "NR3C3, PR" ENSG00000082175 "Progesterone receptor" P06401 11 101029624-101129813 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 63.9;endometrium 1: 103.4;fallopian tube: 34.3;smooth muscle: 78.4" "Cell type enhanced" "Detected in many" "Early spermatids: 64.0;Endometrial ciliated cells: 90.1;Endometrial stromal cells: 177.1;Glandular and luminal cells: 76.3;Late spermatids: 40.9" "Group enriched" "Detected in some" 13 "breast cancer: 10.1;endometrial cancer: 11.1" "Group enriched" "Detected in many" 5 "hypothalamus: 7.7;thalamus: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 338 "T-47d: 170.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000068, HPA004751, HPA008428, HPA017176, CAB055100" Enhanced NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 36: Stromal cells - Cell proliferation" "CAB000068: AB_442124, CAB055100: AB_2532076, HPA004751: AB_1079681, HPA008428: AB_1079680, HPA017176: AB_1855728" "unprognostic (2.59e-2)" "unprognostic (9.80e-3)" "unprognostic (5.23e-3)" "prognostic favorable (5.76e-8)" "unprognostic (2.81e-2)" "unprognostic (1.56e-1)" "unprognostic (4.11e-1)" "unprognostic (1.64e-1)" "unprognostic (2.08e-1)" "unprognostic (2.50e-1)" "unprognostic (3.29e-2)" "unprognostic (1.77e-1)" "unprognostic (7.71e-3)" "unprognostic (1.90e-2)" "unprognostic (2.35e-2)" "unprognostic (1.15e-1)" "unprognostic (5.44e-3)" 1.4 1.7 1.3 0.3 1.0 0.0 7.0 0.8 0.9 63.9 0.6 2.4 0.5 103.4 0.8 0.7 34.3 0.9 3.7 0.8 7.7 1.1 0.3 1.4 0.2 1.7 1.7 16.3 0.6 0.3 1.0 1.7 1.7 3.7 0.7 0.1 3.8 9.0 0.6 0.5 0.7 78.4 1.5 1.7 0.6 3.5 9.2 0.2 1.3 1.8 0.2 1.6 10.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 170.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.0 0.8 0.9 0.8 7.7 1.7 1.7 1.7 1.5 9.2 1.2 1.3 3.2 0.0 0.3 0.7 0.1 1.1 0.0 0.0 1.3 35.9 19.8 18.7 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 64.0 90.1 177.1 3.5 0.0 0.0 0.1 0.0 0.1 12.5 0.0 76.3 0.0 34.7 2.9 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 40.9 14.6 1.9 0.0 22.5 0.0 0.0 0.0 1.0 0.3 0.1 0.0 10.5 0.0 0.3 0.0 0.0 0.0 0.2 6.6 1.4 14.9 3.9 2.3 0.0 0.6 0.0 2.3 15.1 0.0 1.0 PHF20 "C20orf104, dJ1121G12.1, TDRD20A" ENSG00000025293 "PHD finger protein 20" Q9BVI0 20 35771974-35950370 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 452.5;Late spermatids: 661.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029619, HPA029620, HPA029621" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear membrane, Cytosol" "HPA029619: AB_10600090, HPA029620: AB_10601110, HPA029621: AB_10602201" "unprognostic (1.21e-3)" "unprognostic (7.30e-2)" "unprognostic (3.20e-2)" "unprognostic (2.35e-3)" "unprognostic (1.36e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (2.76e-1)" "unprognostic (2.17e-1)" "unprognostic (2.64e-2)" "unprognostic (4.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.92e-2)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (7.23e-2)" "unprognostic (1.01e-2)" 12.9 8.2 10.4 12.0 11.5 11.8 12.5 15.4 13.0 10.8 9.4 10.9 6.0 11.8 7.3 11.9 9.2 10.8 11.5 11.2 10.4 7.8 8.2 10.0 14.2 11.6 11.1 13.2 6.8 12.1 5.4 11.7 11.1 10.3 8.4 14.4 9.5 10.8 32.3 8.1 7.8 11.6 9.5 14.7 8.2 11.8 11.8 14.7 10.2 17.6 13.9 10.5 8.5 14.7 18.1 14.2 24.4 36.0 17.3 19.7 22.5 20.2 19.1 19.8 17.2 41.4 13.1 30.1 17.9 27.1 24.4 10.7 22.6 28.2 24.1 13.7 9.6 55.8 26.3 15.6 17.3 27.2 20.8 15.6 38.8 21.0 32.2 23.5 22.1 21.0 23.3 18.8 23.1 10.8 27.6 15.9 12.0 11.9 17.5 20.0 35.9 17.9 15.9 12.4 21.9 17.9 36.0 41.0 18.4 21.8 32.6 20.0 31.1 43.7 9.9 23.0 21.0 17.2 22.0 21.5 32.2 19.5 22.9 17.3 11.2 33.1 12.4 11.5 13.6 15.0 12.5 14.6 10.6 11.1 14.0 14.7 25.9 16.0 16.9 9.9 7.2 9.0 10.4 11.5 15.4 13.0 11.2 10.4 11.6 11.1 11.1 9.5 11.8 14.7 51.2 38.5 41.8 28.4 131.1 34.8 76.6 52.5 31.3 77.4 49.8 53.5 62.2 31.5 43.5 38.6 98.0 106.7 191.0 16.3 37.2 29.8 452.5 39.8 41.6 46.3 36.0 37.6 49.7 19.9 52.5 53.6 23.0 34.7 142.4 41.2 47.2 18.2 54.5 114.4 49.5 27.9 30.5 62.7 84.3 661.6 35.8 87.1 39.2 62.8 62.6 50.0 105.0 34.2 55.2 24.1 26.5 53.4 76.9 60.0 14.0 24.8 50.2 80.7 19.7 65.5 50.6 60.4 47.0 29.8 28.3 22.3 127.8 30.1 28.8 55.4 PHF6 "BFLS, BORJ, CENP-31, KIAA1823, MGC14797" ENSG00000156531 "PHD finger protein 6" Q8IWS0 X 134373312-134428791 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Epilepsy, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 149.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001023 Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA001023: AB_1079606" "unprognostic (2.38e-3)" "unprognostic (8.21e-2)" "unprognostic (1.99e-1)" "unprognostic (3.04e-3)" "unprognostic (6.03e-3)" "unprognostic (5.20e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.81e-1)" "unprognostic (4.85e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (1.09e-1)" "unprognostic (5.96e-2)" "unprognostic (4.84e-2)" "unprognostic (7.45e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" 6.7 18.0 6.6 14.2 7.9 8.4 10.8 10.3 9.3 8.3 6.2 9.1 8.9 9.7 32.7 8.2 7.9 6.6 6.7 7.1 8.4 10.2 7.7 6.8 25.3 8.3 7.8 33.3 9.5 16.3 6.2 9.3 8.4 9.2 10.3 12.0 13.2 11.0 5.0 8.3 8.8 8.1 8.6 13.3 9.3 9.2 7.7 20.8 13.2 6.8 29.8 8.6 7.1 11.5 28.2 22.9 98.7 40.8 17.9 22.9 18.7 27.6 22.1 29.1 35.6 13.9 28.5 45.1 61.8 16.9 28.3 24.6 69.4 31.3 48.6 37.2 32.1 44.3 37.7 16.1 19.2 44.2 23.3 15.3 23.2 31.7 39.2 29.1 41.1 43.1 32.6 21.8 35.8 18.7 71.3 21.8 30.1 38.3 31.0 69.6 36.0 34.5 30.7 33.8 34.1 39.9 21.2 19.3 29.5 29.0 18.0 24.0 31.5 26.8 19.2 34.0 42.9 11.1 27.3 60.5 17.7 51.4 34.3 5.9 6.3 4.1 8.0 6.6 8.7 18.7 8.2 7.3 9.5 12.4 9.6 8.2 2.6 11.0 8.4 11.7 9.1 5.5 6.6 7.9 10.3 9.3 7.1 8.4 8.3 7.8 8.4 8.6 7.7 11.5 25.5 22.4 18.4 13.1 42.7 13.0 14.3 28.7 22.2 22.4 17.5 20.3 16.3 11.5 17.8 16.5 18.8 11.8 27.1 9.9 23.5 14.2 3.7 13.0 29.1 18.7 11.4 31.3 27.8 13.8 7.6 17.2 14.8 18.7 24.6 149.5 20.0 15.2 15.1 18.5 23.4 12.5 10.2 15.5 10.2 3.1 20.8 20.2 7.2 29.0 25.3 27.9 21.6 33.2 46.7 14.4 18.7 15.4 23.1 12.3 9.5 19.8 16.5 19.7 26.3 21.0 21.9 10.3 22.0 25.7 11.5 4.7 22.6 69.3 17.7 11.5 PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76031776 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 159.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1438.7;Basal squamous epithelial cells: 582.8;Urothelial cells: 760.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "monocytes: 1.1;T-cells: 1.6" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 296.3;RPTEC TERT1: 233.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" Nucleoplasm "CAB016160: AB_628117, HPA019000: AB_1855309, HPA063520: AB_2685028" "unprognostic (9.09e-2)" "unprognostic (2.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.51e-3)" "unprognostic (2.33e-1)" "unprognostic (2.60e-3)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-1)" "unprognostic (4.55e-3)" 21.3 31.0 9.9 17.3 10.1 21.8 28.1 8.9 11.0 23.1 6.2 8.9 6.5 13.4 4.4 59.8 7.8 39.3 20.6 10.3 11.3 14.8 67.6 27.1 5.9 10.8 16.9 19.2 17.9 5.3 8.2 14.3 11.3 8.9 10.2 13.8 159.1 8.2 5.8 11.5 8.6 14.8 9.6 19.5 22.5 3.1 11.5 7.4 27.2 1.5 7.5 60.9 33.7 11.3 60.9 71.5 54.9 30.4 25.0 51.6 3.9 50.5 134.7 22.4 30.8 39.7 72.2 0.3 14.8 21.2 73.8 30.7 1.5 84.2 47.9 9.3 1.2 1.5 3.8 68.2 36.3 1.4 15.1 16.2 60.6 93.2 182.6 296.3 54.4 0.1 5.0 1.7 115.8 7.8 0.2 7.9 20.1 36.3 108.7 0.2 14.3 1.8 233.7 135.1 4.0 10.4 8.8 0.8 169.5 67.8 35.5 0.7 50.8 75.8 7.2 89.3 50.4 0.8 0.3 0.2 127.9 0.8 96.7 0.2 0.0 0.0 0.9 0.1 1.5 0.0 0.9 1.0 0.0 0.0 0.1 0.2 0.2 0.0 1.1 0.0 1.6 0.2 9.9 10.1 8.9 11.0 10.3 11.3 10.8 16.9 11.3 9.6 11.5 11.3 98.5 12.8 12.4 7.2 13.0 195.3 1438.7 249.6 582.8 5.2 136.2 140.3 34.8 11.5 44.4 31.3 2.1 4.7 42.9 11.6 84.1 74.8 2.2 11.5 111.2 162.5 117.7 0.0 7.8 43.1 11.5 203.2 55.0 20.4 79.5 7.1 21.4 127.8 94.7 1.7 14.6 41.0 384.5 14.0 123.4 2.1 9.3 110.8 286.4 8.4 24.0 97.8 0.0 142.2 2.7 208.4 27.7 15.4 19.0 116.1 0.2 39.3 12.4 5.2 269.5 59.8 276.3 0.7 3.2 66.3 75.6 7.4 132.8 20.7 18.0 760.3 PHOX2B "NBPhox, PMX2B" ENSG00000109132 "Paired like homeobox 2B" Q99453 4 41744082-41748725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 8.6;brain: 15.2" "Cell type enriched" "Detected in single" 10 "Cardiomyocytes: 1.0" "Not detected" "Not detected" "Region enhanced" "Detected in some" "medulla oblongata: 10.1;pons: 15.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 89 "SH-SY5Y: 132.7" "Region enriched" "Detected in single" 17 "pons and medulla: 5.6" "Group enriched" "Detected in some" 18 "medulla oblongata: 1.4;pons: 2.0" "HPA074325, HPA074941" Enhanced Enhanced Nucleoplasm NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA074325: AB_2686678, HPA074941: AB_2732272" "unprognostic (1.01e-1)" "unprognostic (2.47e-1)" "unprognostic (5.27e-2)" 0.0 8.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 3.7 0.0 0.1 0.0 0.0 0.0 15.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 132.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 3.7 15.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 500.3;Oligodendrocytes: 709.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 40000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019053: AB_1855361, HPA019061: AB_1855362" "unprognostic (9.27e-3)" "unprognostic (7.29e-2)" "unprognostic (3.51e-1)" "unprognostic (6.83e-2)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (5.36e-3)" "unprognostic (9.02e-3)" "unprognostic (9.80e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.31e-1)" "prognostic favorable (2.02e-6)" "unprognostic (1.26e-2)" "unprognostic (5.21e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" 183.5 62.5 97.1 120.4 162.1 111.4 111.5 119.3 118.7 86.4 43.8 86.3 106.3 79.3 52.4 109.1 66.1 127.0 87.9 91.7 110.8 168.5 147.0 99.4 82.7 125.2 130.7 94.4 80.6 120.6 36.5 157.2 131.6 73.1 83.1 71.5 62.3 93.6 75.8 74.2 115.5 135.3 106.0 126.5 73.0 64.9 120.7 93.1 75.7 101.9 96.7 139.5 73.5 194.7 167.0 78.4 121.1 85.9 185.5 188.8 228.5 211.7 274.7 164.4 143.0 310.7 222.4 126.0 210.8 342.6 171.1 134.6 129.4 154.2 232.8 38.6 45.0 364.9 101.5 98.9 185.6 87.2 158.3 166.6 161.7 308.7 253.3 275.1 178.7 85.9 239.1 103.0 305.2 98.2 103.9 76.8 66.9 269.0 42.7 69.8 182.2 91.1 312.5 139.2 72.9 58.7 258.4 85.4 68.7 156.5 115.6 67.0 196.9 298.6 104.1 355.0 170.2 36.7 107.1 118.4 70.8 64.6 206.6 6.4 13.5 7.5 5.7 11.7 4.9 3.1 4.2 8.0 11.4 2.1 4.2 4.0 40.6 7.1 12.5 3.9 6.4 5.3 97.1 162.1 119.3 118.7 91.7 110.8 125.2 130.7 131.6 106.0 120.7 194.7 147.1 35.3 58.9 134.5 33.3 116.0 44.4 33.0 30.1 20.8 34.8 28.6 46.4 42.9 34.3 71.7 12.5 42.9 43.9 64.2 31.3 57.7 59.3 32.3 32.8 98.7 25.1 88.8 144.7 37.6 127.1 44.6 34.1 50.9 48.2 23.2 71.4 52.3 85.0 40.4 140.7 30.1 30.5 142.8 229.2 95.4 35.8 127.4 60.5 500.3 92.1 22.6 32.0 188.0 709.3 90.2 55.3 43.6 39.1 49.5 71.4 84.0 41.0 16.3 78.9 36.4 92.7 17.3 14.1 34.4 96.5 41.3 38.9 23.6 30.6 77.7 PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2641.0;salivary gland: 1645.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7090.1;Intestinal goblet cells: 2361.1;Paneth cells: 3208.3;Proximal enterocytes: 1558.6;Undifferentiated cells: 4954.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "EFO-21: 36.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" NA NA 1300000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" 2.4 0.5 0.4 187.3 0.2 0.3 131.0 0.5 0.4 547.0 0.2 1693.4 2641.0 20.5 0.2 12.4 3.6 455.0 0.5 0.4 0.2 108.9 34.5 101.6 1.7 0.2 0.2 0.6 13.3 0.1 1.3 0.3 0.4 13.6 1222.6 0.1 1645.1 5.3 0.3 0.6 809.8 39.1 0.1 0.8 414.6 0.3 0.6 0.4 0.2 0.0 0.6 80.3 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 36.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 1.9 0.3 0.0 0.0 0.2 0.0 6.9 0.2 1.7 0.8 2.5 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.3 0.6 0.3 0.4 1.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.3 0.8 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.4 0.2 0.5 0.4 0.4 0.2 0.2 0.2 0.4 0.1 0.6 0.6 2.1 93.0 604.3 0.0 22.1 0.3 4.0 106.6 0.0 0.0 392.4 192.0 1.4 876.4 638.4 108.5 0.0 0.1 2.5 7090.1 17.6 92.5 0.0 65.9 14.6 5.4 426.4 2.7 0.0 64.5 0.0 4.7 482.1 120.1 52.0 0.0 1.8 28.0 0.4 0.0 0.0 2361.1 59.0 2.2 1.1 0.0 0.0 5.7 1.8 0.0 0.6 0.0 0.0 0.0 0.0 221.5 3208.3 0.0 0.7 53.9 1558.6 328.4 415.4 0.0 0.0 0.0 21.0 0.0 0.0 6.9 0.0 0.0 15.6 0.1 4954.6 761.3 PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Lipid metabolism, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 126.7;Inhibitory neurons: 122.0;Oligodendrocyte precursor cells: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009985, CAB017804" Approved Supported Mitochondria,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Mitochondria "CAB017804: , HPA009985: AB_1079610" "unprognostic (1.81e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-3)" "unprognostic (6.49e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-3)" "unprognostic (5.21e-2)" "unprognostic (4.50e-2)" "unprognostic (1.16e-2)" "unprognostic (2.48e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-2)" 14.7 7.9 3.1 8.1 3.7 12.4 8.5 9.7 8.3 8.7 0.3 6.7 4.2 8.3 4.8 7.9 5.7 8.4 9.5 3.7 3.6 8.2 7.1 7.9 9.2 5.1 4.2 10.3 4.3 11.5 3.4 11.1 5.1 7.3 5.8 12.4 4.5 7.1 7.1 5.5 5.3 8.9 2.3 8.8 5.8 6.1 3.7 13.7 7.9 13.0 9.2 8.6 5.8 6.4 19.9 6.5 9.6 9.2 22.7 27.7 6.5 10.8 16.5 10.9 16.0 5.1 13.0 16.1 21.7 10.8 14.1 5.9 8.4 9.8 16.5 32.0 6.2 22.4 5.2 4.4 10.7 13.1 12.6 16.8 10.6 12.4 15.0 13.4 15.8 12.9 10.6 17.3 18.9 6.9 10.9 8.5 8.0 8.8 7.8 13.9 10.0 16.7 8.5 10.0 5.2 9.9 13.1 10.8 16.1 9.1 19.0 11.1 21.1 10.4 6.5 18.1 13.3 9.3 13.8 29.0 11.3 9.6 5.4 1.3 1.2 0.4 1.2 1.0 0.8 1.5 0.8 0.6 0.8 1.6 1.0 0.8 2.2 0.7 0.9 0.9 0.8 0.3 3.1 3.7 9.7 8.3 3.7 3.6 5.1 4.2 5.1 2.3 3.7 6.4 31.3 32.1 26.8 60.7 28.3 14.7 17.9 11.2 2.2 27.9 14.4 15.2 18.5 5.7 15.9 7.3 31.3 10.2 17.9 8.7 1.9 10.7 2.0 14.1 21.7 25.6 2.4 9.2 126.7 13.9 6.1 23.5 8.6 21.6 31.6 19.9 33.5 21.9 11.1 38.7 122.0 10.3 14.2 23.5 24.3 3.4 32.6 20.9 14.2 75.9 24.5 17.4 18.6 130.2 84.2 16.9 10.8 39.5 15.1 34.6 9.5 14.8 20.1 27.1 26.3 25.7 28.6 11.8 10.2 9.8 14.9 8.8 19.9 19.6 9.2 32.0 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106908980 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 43.6;lymphoid tissue: 19.7" "Cell type enhanced" "Detected in some" "B-cells: 24.9;dendritic cells: 26.5;Early spermatids: 28.9;granulocytes: 20.8;monocytes: 23.8;NK-cells: 25.7;Plasma cells: 88.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 29.4;HL-60: 28.8;HMC-1: 34.9;Karpas-707: 29.1;MOLT-4: 56.0;U-266/70: 71.4;U-937: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" Cytosol "HPA069976: AB_2686224" "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 3.1 1.8 0.5 11.5 0.6 43.6 1.9 0.8 1.3 1.9 1.3 4.2 4.1 1.3 0.5 1.7 1.4 3.2 1.6 0.5 1.0 1.0 2.0 4.9 19.0 2.5 1.3 1.6 0.3 0.7 0.2 2.9 2.7 1.0 3.8 0.1 1.3 0.9 0.3 0.8 4.3 2.7 1.8 11.0 4.0 5.2 2.0 16.4 1.1 1.0 19.7 4.3 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 2.7 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 17.9 0.0 0.0 0.0 28.8 34.9 0.0 0.0 0.0 0.0 0.0 11.0 16.9 20.6 29.1 0.0 0.0 56.0 17.6 0.0 0.0 0.0 14.6 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 2.9 0.1 0.2 0.1 0.0 71.4 0.0 27.3 0.1 52.1 6.7 10.8 6.0 24.3 8.8 17.8 8.1 7.3 4.1 6.7 9.4 10.2 4.2 5.9 22.7 9.8 43.7 8.6 4.4 6.8 0.5 0.6 0.8 1.3 0.5 1.0 2.5 1.3 2.7 1.8 2.0 3.9 1.5 0.0 1.8 0.3 24.9 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.6 0.0 0.0 0.0 26.5 0.2 0.0 0.0 28.9 0.1 0.2 1.7 0.0 7.8 5.5 0.0 0.0 0.1 3.6 0.1 20.8 0.4 2.5 0.5 6.8 0.0 0.3 0.0 0.0 11.9 8.3 18.8 0.6 18.9 7.2 15.0 23.8 0.0 25.7 0.0 0.2 0.0 0.0 0.0 88.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 6.6 3.7 0.2 0.3 0.1 18.1 0.6 0.6 0.1 PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215756-68301821 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "dendritic cells: 410.2;Endometrial stromal cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 265.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001216, CAB004268" Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB004268: AB_628126, HPA001216: AB_1079612" "unprognostic (5.74e-2)" "unprognostic (6.58e-2)" "unprognostic (2.01e-1)" "unprognostic (1.31e-2)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "prognostic favorable (8.09e-4)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (1.32e-1)" "unprognostic (4.59e-3)" "unprognostic (5.66e-3)" "unprognostic (1.27e-1)" "unprognostic (5.92e-2)" "unprognostic (1.54e-1)" 60.6 27.3 13.6 27.8 33.3 126.4 92.1 12.5 40.8 51.2 0.6 38.2 17.2 65.8 45.0 43.2 69.0 35.0 72.3 29.9 13.0 35.9 100.8 26.7 28.5 11.2 22.1 53.3 13.4 40.2 7.3 32.4 12.0 26.7 22.2 59.9 64.5 31.9 63.5 28.7 24.5 74.8 9.9 38.1 18.3 8.6 20.3 46.5 20.6 33.9 23.7 27.0 31.7 36.0 4.3 8.2 23.8 71.4 265.5 76.9 10.4 23.2 10.6 8.8 9.4 20.4 7.4 21.8 38.5 32.0 4.3 10.2 6.7 46.9 11.0 90.6 8.9 26.1 6.5 17.0 89.2 27.0 20.1 81.9 104.2 16.1 83.6 4.1 11.7 25.0 4.1 16.1 8.1 11.3 65.7 10.5 6.9 14.7 4.3 61.1 11.3 17.0 11.5 47.9 4.7 21.3 4.0 6.3 15.0 13.7 34.3 19.0 14.0 10.3 10.4 17.3 14.8 18.0 29.2 25.2 11.1 32.9 7.8 22.0 1.7 8.8 11.5 2.4 16.6 1.7 14.9 11.1 3.0 3.9 18.6 14.1 2.2 11.7 6.5 1.2 12.3 5.5 13.6 33.3 12.5 40.8 29.9 13.0 11.2 22.1 12.0 9.9 20.3 36.0 47.7 51.3 24.8 112.3 47.7 14.4 23.5 30.8 175.2 46.0 61.4 168.4 263.0 38.6 19.3 5.5 25.0 13.4 410.2 28.4 72.4 15.8 12.6 38.7 479.9 39.0 9.6 43.5 232.8 9.5 18.5 151.0 43.8 93.2 68.9 110.4 31.1 198.3 30.7 48.8 82.7 32.6 28.5 69.2 24.7 11.9 172.1 68.8 33.8 117.1 37.6 194.1 137.0 281.5 199.9 12.3 19.8 122.2 173.2 8.4 24.3 39.1 8.7 89.4 19.7 127.2 76.5 1.7 4.5 37.2 10.2 10.0 309.9 45.4 36.5 8.1 PIK3R2 "p85, P85B" ENSG00000105647 "Phosphoinositide-3-kinase regulatory subunit 2" O00459 19 18153163-18170532 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 14.4;Undifferentiated cells: 16.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" HPA069291 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA069291: AB_2686109" "unprognostic (2.50e-1)" "unprognostic (1.90e-3)" "unprognostic (1.68e-2)" "unprognostic (1.87e-1)" "unprognostic (2.00e-2)" "unprognostic (9.65e-3)" "unprognostic (1.69e-3)" "unprognostic (2.36e-3)" "unprognostic (9.24e-2)" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (3.36e-1)" "unprognostic (1.69e-2)" "unprognostic (2.02e-1)" "unprognostic (6.35e-3)" "unprognostic (8.63e-2)" "unprognostic (2.00e-2)" 7.2 25.6 26.2 6.9 22.9 9.7 7.6 1.1 41.5 17.6 2.0 13.4 20.5 17.5 12.0 26.0 16.7 12.3 12.8 41.0 6.7 9.5 10.5 9.1 5.2 4.4 7.1 21.5 11.0 20.8 21.5 8.7 4.9 15.5 9.6 7.9 15.0 10.4 12.4 26.3 16.7 9.8 4.7 8.7 15.1 11.5 9.4 11.6 10.5 9.9 6.2 15.3 15.3 16.4 39.1 18.0 25.4 36.8 35.3 36.6 40.5 29.4 38.3 21.6 16.6 18.3 20.4 28.0 48.8 41.9 17.5 28.7 15.6 33.2 11.3 25.0 65.5 10.8 21.3 44.0 29.7 24.6 13.4 45.7 36.4 15.0 21.5 36.8 6.6 11.9 33.6 10.8 30.3 57.0 21.5 17.0 32.9 35.8 48.5 19.6 33.4 23.5 37.7 22.8 63.0 68.0 27.1 28.5 28.9 16.0 19.1 15.8 11.4 40.9 20.8 49.2 27.5 22.9 26.4 10.9 33.9 39.4 26.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 26.2 22.9 1.1 41.5 41.0 6.7 4.4 7.1 4.9 4.7 9.4 16.4 1.0 6.4 1.1 7.2 0.8 1.9 1.3 1.0 1.8 6.3 3.6 3.2 1.5 2.8 1.0 3.7 4.2 1.7 0.8 6.9 0.0 6.0 0.3 1.3 1.7 0.8 6.1 7.4 11.7 6.2 2.9 1.7 1.1 0.8 2.5 1.4 1.4 1.3 2.2 10.1 11.2 10.5 0.0 4.7 1.0 0.0 1.8 1.7 0.0 3.7 1.6 5.7 0.0 10.6 9.2 6.4 7.0 1.9 0.9 1.1 14.4 1.1 0.5 4.3 0.0 1.4 1.4 0.5 2.1 1.3 2.3 1.2 0.9 3.2 16.4 0.6 PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 199.0;Endothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.8" "Group enriched" "Detected in many" 9 "granulocytes: 5.8;monocytes: 2.4;T-cells: 2.3" "Cell line enhanced" "Detected in all" "RT4: 76.1" "Low region specificity" "Detected in all" "HPA005751, HPA071988" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Nucleoplasm "HPA005751: AB_1855350, HPA071988: AB_2686479" "unprognostic (1.98e-1)" "unprognostic (3.75e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.32e-2)" "prognostic favorable (3.62e-4)" "unprognostic (4.88e-2)" "unprognostic (3.33e-3)" "unprognostic (4.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.99e-3)" "unprognostic (2.87e-2)" "unprognostic (9.74e-2)" "unprognostic (6.71e-2)" "unprognostic (8.22e-3)" 31.2 12.2 13.0 7.2 11.2 0.7 28.0 35.9 14.8 15.3 14.0 7.5 3.2 15.9 10.3 7.1 10.1 10.7 35.2 11.4 14.9 16.2 4.0 18.5 6.2 16.7 17.3 4.1 4.7 12.1 8.5 13.3 16.8 12.0 4.9 17.9 12.5 6.1 12.0 6.4 8.6 11.5 15.5 11.2 9.9 25.4 15.9 10.8 14.2 18.5 5.3 14.8 7.4 11.4 10.9 3.6 47.4 24.4 4.6 2.0 15.2 6.3 4.6 8.2 10.1 2.1 3.2 14.3 18.9 2.5 9.9 6.4 16.9 5.8 5.3 11.1 15.0 9.3 41.8 1.6 1.5 8.3 11.8 5.8 3.3 8.7 3.2 7.8 17.3 32.8 3.5 10.0 11.8 16.7 33.4 5.1 16.9 3.1 9.6 42.0 12.7 17.0 20.4 76.1 34.4 24.9 20.5 53.5 5.7 28.5 14.9 7.3 32.4 8.7 8.0 1.5 6.2 14.1 15.8 8.5 6.9 10.9 4.5 0.0 0.2 5.8 2.0 0.3 1.9 0.3 0.4 1.8 0.0 0.0 0.1 1.1 0.0 0.0 2.4 0.3 2.3 0.6 13.0 11.2 35.9 14.8 11.4 14.9 16.7 17.3 16.8 15.5 15.9 11.4 199.0 0.0 8.4 15.7 3.1 2.5 5.4 42.1 14.8 48.3 32.0 30.1 21.1 0.0 28.8 18.4 45.9 4.4 13.9 21.7 0.0 0.6 11.8 13.9 21.0 83.3 7.8 5.9 26.2 1.2 1.1 16.2 55.5 26.2 9.5 6.1 0.0 0.0 1.7 3.3 55.9 8.6 38.7 0.0 4.4 19.9 1.2 8.4 5.4 60.9 0.9 33.5 3.1 22.1 7.1 1.4 1.5 7.9 10.1 7.2 4.5 4.2 26.7 42.8 0.0 13.3 18.0 35.9 31.7 8.0 1.8 1.4 15.7 19.2 6.6 5.0 PIM1 PIM ENSG00000137193 "Pim-1 proto-oncogene, serine/threonine kinase" P11309 6 37170152-37175428 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 219.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 368.2;Suprabasal keratinocytes: 228.6;Urothelial cells: 455.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 321.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 321.3" "Cell line enhanced" "Detected in all" "HEL: 219.9;HMC-1: 391.5;K-562: 192.7;U-698: 735.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003941, CAB017040" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Nucleoplasm, Nucleoli" "CAB017040: , HPA003941: AB_1079618" "unprognostic (1.25e-2)" "unprognostic (4.77e-1)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.91e-2)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (4.64e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (7.32e-2)" "unprognostic (2.14e-3)" "unprognostic (8.16e-3)" "unprognostic (1.04e-1)" "unprognostic (5.26e-3)" "unprognostic (2.90e-1)" 152.8 14.4 8.5 42.3 8.6 219.0 46.2 10.5 10.7 82.9 10.0 45.8 39.2 46.3 2.6 201.5 66.4 52.6 65.4 7.9 11.6 27.0 58.0 49.8 38.5 15.1 12.2 60.4 20.4 3.4 14.8 28.9 12.8 22.5 17.8 8.2 41.1 7.5 36.3 109.8 44.4 38.1 12.3 61.7 40.3 10.7 11.6 26.6 22.7 5.8 26.8 101.6 113.3 12.1 19.1 7.9 12.1 6.7 27.2 14.5 141.9 6.7 20.3 13.5 21.5 28.3 26.2 38.3 10.4 8.0 30.2 21.7 12.7 20.1 12.3 174.4 8.4 219.9 8.7 37.0 27.9 3.8 391.5 49.0 24.5 12.4 8.3 14.9 4.0 9.2 192.7 59.7 2.2 5.0 12.3 19.9 22.7 35.4 12.1 29.7 22.0 45.7 3.9 114.4 58.8 11.9 14.7 1.7 3.8 27.9 3.2 6.5 7.4 7.8 23.3 35.6 8.5 28.0 15.9 735.7 3.4 55.3 8.1 321.3 8.0 113.5 60.3 7.3 77.7 7.1 53.4 53.8 6.3 5.2 47.1 36.9 61.7 39.8 4.2 1.9 41.3 42.1 8.5 8.6 10.5 10.7 7.9 11.6 15.1 12.2 12.8 12.3 11.6 12.1 41.1 22.4 16.0 2.9 35.1 127.8 166.5 63.3 26.7 4.9 9.6 5.3 36.0 18.6 37.6 9.2 0.0 36.5 55.0 50.4 5.9 40.6 4.8 40.3 125.8 33.3 37.1 368.2 2.4 17.2 121.8 67.4 26.0 92.0 49.3 27.5 11.0 33.8 53.6 15.2 2.2 12.4 44.7 44.3 47.4 12.4 8.1 53.9 44.4 4.7 72.3 7.6 112.3 1.0 0.9 60.7 34.2 3.0 190.1 109.6 51.1 17.2 12.9 1.7 0.0 34.2 41.3 14.5 33.9 92.8 228.6 80.7 118.0 1.1 7.8 455.2 PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 102.3;intestine: 87.6;lymphoid tissue: 163.9" "Cell type enriched" "Detected in many" 4 "Plasma cells: 738.8" "Cancer enriched" "Detected in all" 6 "testis cancer: 171.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "HDLM-2: 567.6;Karpas-707: 675.0;RPMI-8226: 703.9;U-266/70: 1218.7;U-266/84: 1160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000285 Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA000285: AB_1079619" "unprognostic (2.34e-3)" "prognostic favorable (4.05e-5)" "unprognostic (8.04e-2)" "unprognostic (7.30e-2)" "unprognostic (6.41e-3)" "unprognostic (2.74e-3)" "unprognostic (2.84e-1)" "unprognostic (5.23e-2)" "unprognostic (2.47e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.17e-11)" "unprognostic (3.36e-2)" "unprognostic (1.96e-2)" "unprognostic (1.27e-1)" "unprognostic (4.38e-2)" 7.9 7.1 10.9 85.4 11.4 102.3 8.8 9.6 12.3 6.1 11.1 40.8 87.6 5.1 10.1 8.2 11.9 16.7 5.2 15.4 12.4 9.8 10.4 23.5 114.3 9.7 10.7 10.3 4.7 3.8 10.1 4.9 11.7 7.4 50.9 5.6 36.4 7.3 2.5 6.3 46.4 6.9 10.3 163.9 45.1 10.1 13.5 45.5 10.1 2.7 104.7 45.6 6.4 8.8 17.5 14.8 8.0 15.4 2.8 2.0 11.7 10.5 13.1 14.8 13.2 13.3 12.9 74.5 4.8 5.3 5.6 10.6 25.1 10.0 14.1 567.6 19.6 90.8 15.0 13.9 6.2 21.7 58.7 5.9 8.4 15.3 9.2 12.1 5.5 9.8 97.8 675.0 8.4 12.6 8.4 45.2 165.2 6.1 22.7 9.9 5.4 703.9 14.9 2.6 5.4 7.8 11.5 8.0 8.3 36.9 19.3 29.8 3.6 3.5 2.5 3.1 10.6 1218.7 1160.5 144.1 14.0 19.0 3.7 279.1 8.2 77.7 60.4 9.7 102.3 124.8 165.9 85.6 13.2 73.5 172.4 113.3 195.5 92.7 17.4 15.2 331.9 79.0 10.9 11.4 9.6 12.3 15.4 12.4 9.7 10.7 11.7 10.3 13.5 8.8 2.9 12.8 36.0 1.0 161.6 20.3 9.0 7.1 45.5 2.6 16.2 4.7 3.5 2.8 9.9 3.7 2.1 5.8 46.8 5.7 3.9 3.3 1.9 15.6 1.0 5.3 13.1 49.9 2.3 3.5 9.1 5.1 10.7 3.9 23.4 1.3 4.2 6.3 7.2 11.8 2.2 7.5 18.3 7.5 123.1 1.8 1.8 19.8 94.3 0.0 99.5 2.2 38.1 0.5 1.0 2.0 3.7 4.1 738.8 4.6 4.1 6.8 16.3 2.1 0.0 3.8 6.2 2.2 1.6 15.7 13.8 2.5 97.1 8.6 11.8 3.4 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960768-49964072 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 408.4;Syncytiotrophoblasts: 389.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 163.3;SK-BR-3: 144.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA068758: AB_2686026" "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 97.8 48.4 25.9 31.3 31.3 114.3 80.2 32.8 38.1 49.2 26.9 55.1 23.8 40.8 12.7 80.8 54.0 25.8 68.7 25.2 32.6 113.3 92.9 107.1 28.2 40.6 36.1 35.7 73.1 21.6 51.3 21.3 38.0 87.3 10.4 3.1 93.5 22.6 112.0 116.4 51.6 9.9 30.3 80.7 118.1 33.9 35.2 19.0 54.9 35.0 13.0 71.0 68.6 39.9 26.8 17.7 11.6 21.9 9.0 6.7 65.5 16.5 26.7 19.4 14.0 29.5 22.3 47.3 20.1 4.6 39.1 22.5 22.3 12.6 6.9 35.8 92.1 19.5 46.3 36.0 41.8 42.5 36.0 12.8 41.0 11.9 20.2 10.5 63.5 31.7 27.0 163.3 5.9 60.6 21.7 76.4 24.2 28.1 27.8 100.3 19.2 57.6 10.6 20.3 41.1 28.6 32.2 144.7 109.2 10.7 19.0 56.4 16.8 12.1 51.5 19.8 27.1 82.2 56.9 41.4 30.1 24.1 33.2 0.0 4.0 0.1 2.2 4.1 2.5 4.3 5.0 4.4 3.1 7.5 4.8 1.9 20.7 1.7 5.2 7.0 5.8 2.7 25.9 31.3 32.8 38.1 25.2 32.6 40.6 36.1 38.0 30.3 35.2 39.9 120.2 64.1 85.9 6.5 107.7 227.3 236.8 79.1 96.8 31.5 99.2 67.3 32.8 121.5 72.8 80.9 2.1 56.9 79.5 57.9 84.1 50.9 5.1 114.2 76.3 167.7 97.7 10.8 10.2 54.5 346.5 69.0 202.3 170.5 69.3 16.8 98.6 45.9 69.7 62.2 6.7 101.7 81.4 41.1 408.4 4.8 32.3 134.8 108.5 6.5 35.8 14.0 11.3 6.6 20.5 71.0 94.6 11.3 95.1 298.4 58.1 88.5 40.9 16.5 26.3 39.4 57.3 26.1 37.7 95.3 204.7 389.9 90.4 11.6 79.0 266.0 PIN1 dod ENSG00000127445 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 1" Q13526 19 9835257-9849689 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 782.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004528, CAB009326, HPA068650, HPA070887" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 120000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "CAB004528: AB_628132, CAB009326: AB_2237080, HPA068650: AB_2686014, HPA070887: " "unprognostic (2.54e-1)" "unprognostic (6.14e-3)" "unprognostic (6.50e-2)" "unprognostic (4.36e-2)" "unprognostic (1.71e-2)" "unprognostic (6.50e-3)" "unprognostic (1.90e-1)" "unprognostic (2.86e-2)" "unprognostic (2.67e-1)" "unprognostic (7.23e-3)" "prognostic favorable (3.25e-4)" "unprognostic (9.43e-2)" "prognostic favorable (7.80e-5)" "unprognostic (2.20e-2)" "unprognostic (2.56e-1)" "unprognostic (3.13e-2)" "unprognostic (1.21e-2)" 55.3 90.1 130.7 31.2 140.6 48.1 52.3 132.5 201.4 59.4 99.9 83.2 36.4 61.7 7.2 59.5 63.7 13.0 105.5 149.6 141.4 70.1 63.2 49.0 26.4 152.6 134.4 54.6 43.5 28.2 69.2 20.5 156.7 74.7 9.3 20.6 39.6 22.0 90.4 54.3 49.0 16.7 113.9 53.8 61.1 98.4 133.8 42.3 44.8 33.4 12.4 67.4 52.4 132.7 116.8 104.5 75.4 70.8 25.8 22.9 45.1 85.3 35.7 60.9 58.3 97.5 36.1 72.0 132.0 31.7 63.8 58.4 52.2 49.6 19.3 153.9 223.5 187.0 137.2 85.5 41.9 88.0 105.0 31.5 33.5 39.5 18.7 45.7 49.9 124.1 86.1 105.4 37.3 81.0 133.7 338.6 72.8 47.8 156.8 120.6 79.4 121.2 44.5 56.4 95.1 112.4 82.0 40.5 96.6 30.8 51.9 104.3 87.3 85.6 68.3 133.6 139.1 135.0 137.0 97.1 90.9 111.3 107.2 280.9 181.0 397.6 170.1 202.0 159.8 165.5 165.5 171.8 171.4 176.5 130.5 146.0 114.0 192.2 195.8 316.9 245.5 214.7 130.7 140.6 132.5 201.4 149.6 141.4 152.6 134.4 156.7 113.9 133.8 132.7 73.8 28.9 20.5 11.1 48.8 48.3 65.7 153.9 23.3 77.3 56.1 62.0 79.6 44.3 67.4 62.5 12.5 119.4 81.3 82.3 164.4 101.5 270.5 75.9 57.6 65.6 99.9 78.9 41.3 108.6 98.1 66.5 38.7 40.6 63.5 83.6 56.4 45.8 140.7 60.6 39.2 70.6 160.7 54.7 75.2 782.4 90.1 60.6 124.5 20.6 131.6 87.9 138.0 11.6 24.3 113.7 81.2 129.8 74.3 68.9 97.0 143.8 104.5 76.0 65.7 52.3 98.6 186.7 94.7 54.0 65.9 55.0 77.8 81.8 69.2 58.5 PIP4K2B "PIP5K2B, PIP5KIIB, PIP5KIIbeta" ENSG00000276293 "Phosphatidylinositol-5-phosphate 4-kinase type 2 beta" P78356 17 38765691-38800126 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062220 Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA062220: AB_2684715" "unprognostic (7.77e-2)" "unprognostic (8.37e-2)" "unprognostic (3.74e-2)" "unprognostic (1.13e-1)" "unprognostic (2.67e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (4.54e-4)" "unprognostic (2.64e-1)" "unprognostic (2.33e-1)" "unprognostic (1.50e-2)" "unprognostic (6.10e-3)" "unprognostic (3.79e-1)" "unprognostic (4.82e-3)" "unprognostic (3.38e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.36e-4)" "unprognostic (2.48e-1)" 19.9 27.0 82.5 15.5 85.6 7.3 20.8 62.3 93.9 30.1 43.3 24.2 10.3 28.8 23.3 15.4 29.1 16.3 30.2 90.7 75.2 20.1 14.4 21.4 20.5 65.9 65.7 49.8 16.4 16.6 25.2 22.8 67.1 22.2 14.0 36.0 16.9 25.3 99.0 24.6 17.3 29.5 63.2 23.2 16.4 13.0 80.4 23.4 20.3 75.6 20.4 22.9 20.9 81.4 18.1 40.2 66.0 69.9 56.7 45.5 12.2 31.6 38.2 43.1 35.0 28.2 18.4 44.8 17.2 59.8 36.3 35.9 44.9 28.7 41.4 27.8 17.2 38.4 27.3 40.7 26.2 43.7 23.5 40.0 34.2 33.7 24.2 59.2 36.3 48.6 34.2 22.3 46.8 14.2 44.0 34.0 32.0 20.7 15.8 44.6 63.7 25.6 31.3 22.3 34.0 46.1 30.9 13.9 34.5 68.5 43.6 44.5 33.4 35.8 21.6 29.4 28.9 27.4 36.5 19.7 42.0 36.8 32.9 1.3 1.9 0.6 3.4 1.6 3.5 2.3 2.9 3.3 2.4 2.3 3.2 2.9 1.8 2.8 1.4 2.2 3.0 3.3 82.5 85.6 62.3 93.9 90.7 75.2 65.9 65.7 67.1 63.2 80.4 81.4 15.8 19.2 11.4 21.5 6.7 6.1 3.5 4.6 7.4 31.6 11.5 13.3 23.4 4.3 7.5 5.5 10.4 7.0 14.8 3.7 1.9 5.3 9.2 10.8 17.7 17.3 11.5 9.0 33.5 4.9 5.0 13.8 5.6 9.0 1.3 22.6 18.2 12.7 8.8 43.7 29.1 7.4 2.0 11.3 4.9 21.1 15.2 8.6 1.8 18.7 6.9 14.8 10.3 22.1 24.0 6.0 4.1 16.6 6.2 4.9 5.4 7.7 6.4 14.0 6.6 13.8 13.2 4.6 7.4 9.9 4.4 2.5 8.1 17.3 7.2 2.7 PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: AB_10602116" "unprognostic (1.05e-1)" "unprognostic (2.36e-2)" "unprognostic (8.64e-2)" "unprognostic (7.94e-3)" "unprognostic (1.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.16e-7)" "unprognostic (1.44e-1)" "unprognostic (8.14e-2)" "unprognostic (2.93e-1)" "unprognostic (1.59e-1)" 20.1 19.1 16.0 16.1 17.3 9.7 19.5 17.8 19.2 18.9 20.8 17.2 16.2 18.8 21.1 20.4 18.9 19.7 19.8 16.8 17.3 21.9 18.6 21.8 18.7 15.1 15.7 18.7 13.6 23.0 21.5 25.9 14.7 16.7 15.1 30.1 16.9 14.1 29.2 21.0 16.9 20.3 14.2 19.0 16.6 35.1 16.9 24.7 18.4 25.4 20.1 20.5 17.4 18.4 49.3 37.4 57.7 67.6 37.5 38.8 56.7 63.5 89.3 116.6 103.7 68.7 46.8 43.9 66.8 67.9 52.7 42.0 75.7 42.6 101.2 68.8 54.0 36.0 48.4 33.9 70.1 64.9 43.8 51.1 40.3 72.7 90.7 52.1 48.8 69.4 35.6 36.7 60.4 69.9 63.6 32.4 86.0 38.2 58.3 60.5 50.7 34.1 61.2 27.1 38.6 49.4 87.1 66.6 57.4 96.4 69.2 59.4 47.4 46.6 64.7 42.6 77.0 50.5 93.6 99.3 44.7 18.6 56.6 0.1 3.9 5.7 3.7 4.7 2.8 6.6 3.3 4.1 6.4 3.0 3.7 2.9 8.9 3.9 3.8 6.7 3.1 4.7 16.0 17.3 17.8 19.2 16.8 17.3 15.1 15.7 14.7 14.2 16.9 18.4 11.6 32.1 12.2 43.8 21.3 66.2 23.2 17.0 39.9 34.1 31.3 22.0 18.4 17.2 15.3 31.3 98.0 25.9 18.3 12.7 9.8 13.5 4.9 64.0 26.2 15.6 6.0 12.4 59.6 8.7 29.3 19.8 19.4 71.0 12.0 19.9 14.3 14.3 12.8 26.9 51.2 9.7 18.3 10.7 29.5 4.8 13.4 14.9 12.4 44.0 12.2 12.5 9.2 54.8 64.0 19.4 8.9 10.9 16.8 20.9 21.0 10.1 18.4 43.0 13.1 17.4 20.9 52.1 24.6 38.4 50.0 63.5 15.9 18.4 10.7 39.4 PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231822 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Translation regulation" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 4207.6;tongue: 2900.8" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 2065.2;Late spermatids: 1763.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced Cytosol No No 310000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB019421: AB_2252325, HPA029501: AB_10602118" "unprognostic (8.73e-3)" "unprognostic (4.63e-3)" "unprognostic (1.68e-2)" "unprognostic (3.09e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (1.30e-4)" "prognostic unfavorable (2.74e-6)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.51e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (5.17e-5)" "unprognostic (3.16e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-2)" 190.5 600.9 539.0 341.4 552.3 439.0 190.5 586.8 629.9 406.8 755.0 225.0 170.8 202.8 205.7 658.3 240.0 212.0 779.6 549.1 561.6 549.5 32.2 236.9 284.1 640.0 559.1 169.4 112.6 269.6 224.1 168.6 636.2 252.6 206.2 1266.7 389.8 291.6 4207.6 350.5 218.0 298.9 522.3 239.2 228.6 235.1 677.1 203.5 174.6 2900.8 429.2 578.5 374.9 530.6 1584.6 3937.1 788.9 938.8 914.3 1009.4 638.7 1684.6 3878.2 2619.1 2623.6 1094.4 1931.2 1184.5 1627.3 3157.6 1937.8 2253.9 2480.9 3383.2 2051.7 2134.0 1126.5 727.7 1809.1 929.7 637.1 955.2 1525.1 926.4 1559.2 2025.1 810.9 3403.0 1558.6 587.3 182.8 933.3 4267.0 965.1 359.4 419.6 966.2 2438.6 1433.3 1046.5 2560.0 2301.7 3557.2 1973.8 804.4 871.5 2226.3 1344.7 1755.4 1291.4 932.0 675.7 1247.3 3003.7 1622.0 2928.7 3110.3 1170.0 1762.1 1037.2 3720.5 1534.4 3002.3 131.9 836.3 138.6 192.6 466.7 187.9 205.2 254.1 190.4 685.6 142.9 215.8 162.5 100.7 108.4 380.1 140.5 334.0 1261.7 539.0 552.3 586.8 629.9 549.1 561.6 640.0 559.1 636.2 522.3 677.1 530.6 95.9 118.6 88.1 107.7 169.6 565.5 708.9 2065.2 307.9 480.7 157.8 174.7 313.2 87.2 759.4 829.4 369.1 566.1 100.2 358.9 802.2 1395.6 315.0 169.2 77.3 207.7 282.2 44.8 90.2 597.0 1416.7 220.1 138.1 188.0 206.7 144.0 73.2 4.3 750.0 1065.0 97.6 166.8 925.7 297.7 532.9 1763.1 157.2 558.8 355.8 38.4 1255.0 784.1 78.2 53.3 33.4 1213.2 264.5 268.1 209.9 431.4 389.1 208.7 396.9 708.6 124.9 160.9 398.2 43.4 98.6 341.6 389.0 575.7 192.7 157.4 380.7 860.7 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917496 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 103.8;urinary bladder: 128.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 635.9;Basal respiratory cells: 237.3;Pancreatic endocrine cells: 613.9;Prostatic glandular cells: 695.0;Urothelial cells: 869.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 1.1;neutrophil: 2.1;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 11 "dendritic cells: 2.0;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 856.0;LHCN-M2: 822.4;RPTEC TERT1: 3100.7;U-251 MG: 869.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070796 Supported Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 647000 88000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Vesicles" "HPA070796: " "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favorable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" 57.6 4.8 2.5 41.7 2.7 36.2 17.6 2.7 8.9 9.3 4.4 13.1 11.9 22.0 16.7 14.4 10.3 28.5 23.1 2.4 2.9 103.8 5.0 22.0 14.3 3.8 2.9 2.3 10.1 8.3 2.9 36.5 5.4 9.1 18.2 0.3 17.3 13.7 10.8 25.5 13.7 23.4 3.3 40.6 15.7 3.7 4.7 5.9 17.9 18.9 7.2 128.5 16.2 4.7 171.1 88.9 36.8 1.7 3.1 59.5 2.0 101.9 461.6 40.0 62.2 2.3 856.0 0.1 184.0 14.5 416.9 114.1 0.9 165.8 44.8 9.9 0.0 0.1 4.4 1.7 72.6 15.6 32.3 158.7 20.2 271.4 103.7 447.0 114.7 1.0 1.1 0.9 822.4 0.2 0.2 22.7 10.8 0.3 244.5 0.4 112.6 0.9 3100.7 130.6 0.1 0.2 0.3 4.0 2.4 25.4 1.2 22.9 300.6 3.5 20.3 21.6 869.8 0.2 1.3 1.6 216.0 25.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.1 0.0 0.0 2.0 0.0 0.1 2.5 2.7 2.7 8.9 2.4 2.9 3.8 2.9 5.4 3.3 4.7 4.7 29.0 3.2 4.6 0.3 1.4 37.3 635.9 237.3 19.9 0.0 3.0 24.4 2.5 0.0 103.6 29.5 0.0 28.0 1.6 0.6 68.4 62.7 0.5 50.7 22.2 46.4 3.5 0.0 0.2 21.3 21.7 69.7 0.0 68.9 31.1 0.1 3.9 0.0 39.8 0.0 0.3 0.1 140.4 4.0 33.1 1.3 2.5 53.4 7.2 4.7 23.8 0.0 0.0 0.5 0.2 613.9 0.3 0.0 0.5 695.0 0.0 1.4 35.4 0.0 6.6 27.6 65.2 0.0 0.2 60.6 29.5 17.5 4.7 0.6 1.7 869.6 PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 688.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 820.7;Langerhans cells: 1833.9;Macrophages: 864.3;Urothelial cells: 2274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1172.3" "Group enriched" "Detected in all" 4 "granulocytes: 1172.3;monocytes: 550.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 311.7;U-251 MG: 413.1;U-87 MG: 346.9;WM-115: 346.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB073533: , HPA050843: AB_2681255" "unprognostic (9.28e-2)" "unprognostic (9.65e-3)" "unprognostic (1.39e-1)" "unprognostic (1.29e-3)" "unprognostic (3.59e-3)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "prognostic unfavorable (2.33e-5)" "unprognostic (8.08e-3)" "unprognostic (4.30e-2)" "unprognostic (2.29e-3)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.83e-9)" "unprognostic (4.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.45e-2)" "unprognostic (9.33e-2)" 52.1 10.4 7.5 81.7 9.8 688.4 14.5 11.2 32.4 30.9 10.3 26.7 10.0 30.2 4.8 11.6 22.8 78.1 23.0 8.1 10.4 18.2 19.8 69.5 10.6 12.2 9.8 14.9 13.6 5.4 9.1 35.9 13.3 11.5 20.1 2.8 21.7 5.8 3.6 7.8 10.6 26.2 9.7 20.4 28.4 3.1 24.8 10.2 9.5 4.7 8.6 109.7 15.8 13.8 83.9 31.0 26.1 1.9 23.4 83.3 16.2 180.7 189.6 114.6 141.4 2.4 95.1 2.4 43.0 116.9 66.8 35.2 7.0 46.4 127.9 5.3 5.3 15.8 44.7 3.9 30.6 18.8 195.2 87.4 9.0 311.7 46.5 160.6 129.0 19.1 16.4 2.2 107.7 6.1 21.0 55.3 8.7 156.1 64.7 24.0 17.4 5.6 35.9 3.8 1.3 22.2 82.0 17.4 25.0 12.6 3.2 59.4 129.7 230.0 121.1 109.8 413.1 3.0 9.0 0.6 346.9 36.0 346.5 87.7 476.5 745.5 6.8 427.9 8.3 2.7 8.9 5.7 213.6 1.4 3.2 4.0 1172.3 6.7 550.7 69.3 3.6 253.9 7.5 9.8 11.2 32.4 8.1 10.4 12.2 9.8 13.3 9.7 24.8 13.8 23.1 73.7 76.6 2.3 15.5 105.2 820.7 274.2 72.3 0.7 45.8 22.5 4.5 24.3 151.9 20.2 0.0 6.5 17.4 314.5 1.9 219.3 0.9 188.1 68.0 64.9 14.8 5.2 2.5 106.5 58.8 145.4 156.0 519.1 305.2 4.2 19.2 1.7 428.9 10.1 3.3 85.3 22.4 155.4 1833.9 2.0 6.8 864.3 72.9 5.6 52.1 1.2 4.1 1.5 0.9 558.8 435.5 4.1 14.5 479.4 12.7 2.7 52.7 0.7 6.6 38.5 90.0 1.2 4.7 202.6 63.1 13.1 33.2 3.1 29.3 2274.4 PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.7;MAIT T-cell: 6.4;memory CD4 T-cell: 4.1;memory CD8 T-cell: 3.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 4.3;NK-cell: 3.4;T-reg: 3.8" "Group enriched" "Detected in many" 9 "NK-cells: 3.4;T-cells: 6.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004277, HPA036681, HPA036682" Approved Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 58: T-cells - T-cell receptor" Cytosol "CAB004277: AB_628119, HPA036681: AB_2675245, HPA036682: AB_2675246" "unprognostic (2.77e-1)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (4.31e-2)" "unprognostic (5.82e-2)" "unprognostic (2.09e-2)" "unprognostic (4.45e-3)" "unprognostic (1.25e-2)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "prognostic favorable (4.72e-4)" "unprognostic (3.32e-1)" "unprognostic (2.73e-3)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (2.79e-2)" 33.3 22.4 36.2 21.7 37.3 10.0 31.8 43.8 41.3 42.5 27.8 25.2 17.8 36.1 13.7 18.9 31.9 19.9 31.9 35.6 32.9 23.2 9.7 32.4 36.4 34.8 36.2 42.6 11.4 13.3 21.6 23.8 34.2 30.2 13.7 10.9 20.2 20.5 18.5 31.5 28.8 22.9 32.0 30.0 19.4 26.3 39.5 60.5 45.0 20.3 24.0 30.4 32.0 38.6 16.6 20.8 97.2 71.6 38.0 26.5 30.9 26.7 34.1 52.4 44.3 50.1 5.4 37.0 31.9 29.1 55.0 30.2 42.7 47.8 30.4 10.5 22.7 2.6 36.4 59.6 28.9 14.7 9.7 34.1 26.3 38.8 30.0 47.2 59.4 77.3 28.0 23.6 48.0 123.8 90.7 11.5 36.2 21.3 37.6 71.1 70.8 18.2 28.7 30.1 34.4 65.7 47.8 22.1 48.4 54.1 25.8 17.0 64.6 124.4 40.3 40.2 32.9 26.1 12.4 30.3 29.7 15.6 52.9 0.0 0.0 0.0 4.7 0.0 6.4 0.2 4.1 3.9 0.0 0.5 4.3 4.3 0.0 3.4 0.0 0.0 3.8 3.0 36.2 37.3 43.8 41.3 35.6 32.9 34.8 36.2 34.2 32.0 39.5 38.6 33.4 16.0 7.0 69.2 5.1 5.6 1.8 5.3 14.8 4.3 4.7 5.8 9.6 1.5 3.8 3.7 10.4 1.9 7.4 9.4 0.0 3.3 7.0 5.4 16.9 24.2 1.8 2.1 9.7 1.6 2.0 11.5 10.2 10.3 1.3 19.8 11.7 3.1 4.0 3.3 9.1 9.5 4.1 2.9 4.3 7.2 15.2 1.7 3.6 16.9 1.2 6.7 2.1 13.0 16.4 3.3 4.8 18.4 6.3 2.3 7.8 3.0 1.8 5.1 13.1 8.5 10.2 15.9 13.0 6.1 7.0 0.8 17.0 5.7 6.4 0.9 PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 706.3;choroid plexus: 347.5" "Cell type enhanced" "Detected in many" "Adipocytes: 187.0;Bipolar cells: 224.8;Muller glia cells: 221.7;Rod photoreceptor cells: 196.2" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 183.3;HMC-1: 84.2;REH: 75.1;U-698: 403.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 8200 "Cluster 5: Granulocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" 9.0 4.2 69.4 33.0 141.3 30.3 8.5 706.3 105.2 5.0 347.5 8.6 17.3 8.6 22.5 4.6 5.5 13.4 4.3 40.1 122.6 23.4 14.3 9.4 66.8 301.3 122.7 1.6 3.9 2.8 1.2 8.2 207.3 2.8 7.0 0.5 7.1 3.4 1.9 4.0 19.4 8.8 241.5 34.8 8.7 2.0 283.3 10.0 6.9 3.6 72.0 10.1 3.9 437.2 1.4 3.2 0.6 2.9 0.2 0.2 4.0 0.3 0.4 2.3 0.8 0.9 8.1 183.3 30.1 0.2 7.4 4.2 4.0 0.5 1.4 1.4 2.1 22.1 0.4 0.3 1.2 22.3 84.2 0.3 1.8 1.3 1.0 0.3 4.2 8.1 2.5 15.0 0.4 5.7 2.6 55.5 3.1 2.3 1.3 75.1 0.1 23.7 0.5 3.9 1.4 0.4 5.0 1.6 1.5 3.9 3.3 67.7 1.1 0.4 3.2 0.4 0.6 35.2 61.4 403.4 0.3 30.0 1.6 9.4 12.1 76.2 1.9 16.1 0.9 51.1 0.6 2.9 10.7 49.6 0.8 1.9 65.7 41.3 36.8 7.0 0.5 6.9 69.4 141.3 706.3 105.2 40.1 122.6 301.3 122.7 207.3 241.5 283.3 437.2 187.0 12.8 54.0 0.0 138.3 2.9 1.6 2.3 1.8 224.8 139.5 113.0 7.2 28.6 13.1 16.5 104.3 13.6 94.0 0.4 13.7 2.6 20.5 65.5 88.0 61.7 21.5 23.2 0.7 0.0 2.2 30.6 16.8 86.6 40.4 29.0 37.1 43.2 27.7 101.0 0.8 2.7 65.1 47.4 9.4 30.7 11.1 46.7 8.8 95.5 21.8 221.7 47.4 2.0 1.3 0.1 9.8 4.9 138.6 3.5 5.5 5.9 6.9 196.2 6.6 28.0 51.9 4.8 2.9 3.0 2.3 11.1 48.2 8.7 1.9 6.5 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 256.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 384.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 41.8 30.9 44.2 22.6 25.4 43.2 37.9 20.4 39.7 57.4 6.7 58.0 21.1 55.2 8.5 59.7 47.9 22.8 78.9 42.2 31.0 30.0 31.3 49.2 22.1 48.5 28.6 47.1 27.6 8.1 33.0 18.3 30.8 49.5 13.0 3.9 42.9 19.8 256.5 83.1 53.8 27.7 28.8 46.1 49.1 15.3 43.2 14.4 25.7 74.7 15.8 56.5 55.7 25.9 92.6 247.3 15.1 20.3 31.6 66.9 62.8 125.9 49.3 32.3 18.7 39.2 88.5 8.9 82.9 179.7 54.6 98.9 10.3 162.6 13.3 58.7 10.0 24.9 268.0 34.0 54.0 9.6 26.1 71.8 40.7 84.6 164.2 28.3 43.0 7.6 16.2 25.9 39.7 175.3 5.1 19.8 12.2 29.4 384.8 1.8 46.2 24.6 67.7 147.7 16.6 16.8 217.4 50.0 21.1 21.7 55.7 12.4 125.7 117.8 217.3 110.6 155.1 4.7 3.7 6.3 106.9 15.2 176.2 0.0 2.0 0.1 0.6 1.7 1.3 0.6 1.2 0.9 1.6 0.6 0.8 0.5 0.4 0.3 1.2 1.3 1.4 2.0 44.2 25.4 20.4 39.7 42.2 31.0 48.5 28.6 30.8 28.8 43.2 25.9 83.8 28.9 15.6 78.0 27.0 108.0 53.1 62.9 50.7 15.8 29.4 27.9 39.3 31.5 42.9 40.5 25.0 34.4 27.1 257.8 0.0 39.3 1.4 39.4 52.6 68.2 32.2 11.8 47.3 20.2 32.1 45.7 170.2 57.3 8.2 14.4 63.1 69.0 35.2 30.3 36.5 79.9 10.2 67.5 100.4 5.0 44.4 61.2 33.8 27.2 54.9 11.2 15.5 14.6 3.4 157.8 194.1 74.9 39.3 144.9 124.9 4.6 50.3 10.8 6.6 42.1 61.5 1.2 7.1 72.2 76.7 69.0 35.0 18.8 61.6 121.0 PLG ENSG00000122194 Plasminogen P00747 6 160702238-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2666.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1772.7" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000668, CAB016678, HPA021602, HPA048823" Supported "Secreted to blood" NA NA 140000000000 45000000000 "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" 0.4 0.4 0.3 0.2 0.4 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.3 0.2 0.0 0.1 2.4 0.5 0.1 0.2 0.3 240.9 2666.4 0.4 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.6 30.0 0.0 1.8 0.0 0.0 0.3 0.0 19.6 0.0 0.2 3.0 0.1 1.2 0.0 24.0 0.6 0.0 0.0 0.0 0.0 0.1 1.3 0.0 28.5 1772.7 0.1 0.0 0.5 0.0 0.0 35.4 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 235.7 1.5 0.1 0.0 0.4 0.2 0.4 0.4 0.0 0.0 0.0 2.3 0.1 0.0 0.0 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.0;lymphoid tissue: 43.9;testis: 33.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.3;Early spermatids: 123.7;Erythroid cells: 38.3;Extravillous trophoblasts: 55.9;Spermatocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 5.6" "Lineage enriched" "Detected in many" 5 "T-cells: 5.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051638, HPA053229" Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA051638: AB_2681561, HPA053229: AB_2682084" "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (2.70e-7)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 1.4 1.5 2.3 13.4 2.3 32.0 1.5 2.5 3.2 2.3 2.0 9.6 10.4 1.2 0.4 13.9 1.0 1.4 1.0 2.3 2.1 1.4 1.9 1.9 27.8 2.3 2.3 1.3 1.1 0.2 1.2 6.4 2.2 1.2 10.1 1.2 2.4 0.3 1.0 5.7 9.2 4.0 2.0 9.1 6.2 33.1 2.5 43.9 0.9 0.4 30.0 2.8 4.0 2.8 199.9 207.5 166.2 90.9 5.2 11.7 92.8 111.0 74.5 172.5 127.0 184.3 131.0 99.1 56.3 76.5 90.1 112.8 229.5 93.5 206.1 139.5 128.0 125.2 163.4 257.1 1.7 147.5 133.7 4.8 5.2 124.7 125.2 21.6 127.9 127.5 200.7 133.9 134.8 187.8 139.8 151.4 189.5 82.1 103.5 217.2 111.7 160.0 49.3 43.9 94.3 65.3 126.8 88.9 55.8 94.4 114.4 92.1 65.1 82.7 102.7 79.9 194.1 93.2 156.8 173.6 69.3 127.7 137.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.3 0.3 0.0 0.0 0.0 0.4 0.9 0.0 0.0 5.6 1.4 2.3 2.3 2.5 3.2 2.3 2.1 2.3 2.3 2.2 2.0 2.5 2.8 0.6 3.2 0.0 3.3 7.6 1.3 1.2 6.5 0.0 1.4 1.7 2.3 0.6 0.0 1.4 0.0 4.2 32.3 0.4 5.5 0.0 0.8 123.7 3.4 1.3 2.5 0.0 38.3 3.1 0.8 55.9 4.7 10.2 1.8 1.3 19.9 3.3 1.1 20.8 0.0 2.3 7.3 4.1 6.9 3.2 13.9 1.2 7.2 0.0 2.8 0.4 1.1 0.0 1.5 2.3 1.2 0.3 0.7 23.0 2.0 1.5 0.1 1.3 1.3 0.0 2.3 6.1 79.5 13.5 12.2 1.8 3.8 2.5 1.2 17.9 2.0 PLP1 "GPM6C, PLP, SPG2" ENSG00000123560 "Proteolipid protein 1" P60201 X 103773718-103792619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 7004.9" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 4822.5" "Group enriched" "Detected in many" 22 "glioma: 160.5;melanoma: 75.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SK-MEL-30: 241.0;WM-115: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004128 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004128: AB_1079635" "unprognostic (5.72e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-2)" "unprognostic (4.09e-3)" "unprognostic (1.32e-1)" "unprognostic (3.95e-2)" "unprognostic (2.57e-2)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-5)" "unprognostic (4.91e-2)" "unprognostic (1.86e-1)" "unprognostic (3.46e-2)" "unprognostic (1.16e-2)" 7.3 15.7 2252.5 4.2 4296.1 0.1 5.4 4251.8 3472.7 17.8 1056.0 73.9 6.3 6.8 6.7 9.9 7.3 9.6 30.1 2314.1 2859.4 2.9 2.0 1.2 0.4 5976.3 3571.3 5.7 2.5 83.1 6.4 0.0 5342.5 21.1 14.9 7.5 6.7 30.0 2.4 24.4 22.4 22.7 3919.9 0.5 15.4 33.5 3592.5 3.8 3.4 6.8 0.4 12.9 21.8 7004.9 0.2 0.0 20.7 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.8 1.9 0.0 0.0 0.2 0.7 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 4.0 0.0 0.2 0.0 0.9 0.0 0.1 0.0 2.8 0.0 0.0 0.1 0.0 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 241.0 6.3 0.1 0.2 0.0 0.1 0.4 0.1 0.2 0.0 0.3 0.2 4.0 0.0 139.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2252.5 4296.1 4251.8 3472.7 2314.1 2859.4 5976.3 3571.3 5342.5 3919.9 3592.5 7004.9 0.5 0.0 0.0 23.8 0.1 15.9 0.3 0.0 6.2 1.7 0.2 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.0 9.7 0.0 0.0 13.3 0.0 0.0 0.0 188.3 3.3 0.0 0.1 0.0 11.2 0.0 0.0 0.0 5.8 3.1 7.5 0.8 396.6 17.8 0.0 30.7 0.0 31.2 4822.5 0.0 0.0 3.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 3.1 2.4 0.6 0.3 0.8 2.6 0.0 0.2 5.6 0.0 0.1 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 PML "MYL, RNF71, TRIM19" ENSG00000140464 "PML nuclear body scaffold" P29590 15 73994673-74047827 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Biological rhythms, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008312, CAB010194, CAB016304" Supported Enhanced "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear bodies" "CAB010194: AB_2166848, CAB016304: AB_628162, HPA008312: AB_1079643" "prognostic favorable (3.24e-4)" "unprognostic (4.83e-2)" "unprognostic (5.76e-2)" "unprognostic (1.58e-3)" "unprognostic (7.53e-3)" "unprognostic (1.58e-1)" "unprognostic (2.35e-2)" "unprognostic (5.30e-3)" "unprognostic (4.54e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.29e-4)" "unprognostic (2.67e-2)" "prognostic unfavorable (6.27e-8)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.99e-2)" 84.4 29.4 14.4 25.6 13.8 38.1 77.0 11.8 16.4 53.7 11.6 46.7 18.4 47.1 7.5 38.3 44.6 21.6 39.3 13.8 13.1 35.4 25.4 75.2 25.6 18.2 13.8 37.5 20.3 8.3 26.8 23.7 14.8 41.5 8.5 3.9 44.2 17.2 22.5 47.4 39.0 19.5 14.6 48.6 35.3 11.3 15.2 17.0 48.1 7.9 15.2 42.7 44.5 13.1 37.2 13.8 11.8 11.4 30.2 43.2 40.6 18.5 31.6 55.9 63.3 14.6 64.2 16.4 63.7 31.6 53.3 66.6 16.3 37.1 7.6 58.0 25.1 35.8 21.3 16.3 36.9 33.9 31.1 83.7 24.8 37.5 19.2 39.3 38.3 26.1 30.6 28.3 32.7 17.3 28.3 52.6 12.8 7.7 25.0 21.6 13.4 30.8 60.3 59.5 10.1 11.1 29.7 16.3 44.8 10.3 12.8 28.7 66.1 56.6 15.5 28.5 38.1 29.4 20.0 8.0 38.9 42.2 18.2 7.4 14.7 23.4 13.0 20.2 9.8 12.4 10.4 14.1 14.5 10.2 8.2 8.5 12.0 14.5 22.6 9.2 14.3 10.1 14.4 13.8 11.8 16.4 13.8 13.1 18.2 13.8 14.8 14.6 15.2 13.1 127.8 16.0 12.2 8.8 24.9 22.9 14.3 30.4 37.5 8.1 13.5 12.8 10.0 5.7 16.7 5.5 2.1 9.4 18.8 13.1 7.9 25.8 3.4 16.0 16.7 48.0 14.3 29.3 4.7 19.1 15.0 20.7 58.1 26.0 12.0 11.5 32.2 11.3 30.8 8.4 4.8 14.3 14.2 20.1 18.5 4.0 27.7 19.6 7.2 7.5 24.6 8.5 20.6 4.5 6.0 62.8 15.5 24.0 21.6 26.2 22.8 10.4 18.3 5.4 39.5 7.7 20.4 1.1 4.0 27.1 19.6 4.9 20.4 16.8 12.1 26.0 PMP22 "CMT1A, GAS3, HMSNIA, HNPP, Sp110" ENSG00000109099 "Peripheral myelin protein 22" Q01453 17 15229773-15272292 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes, Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 404.1;Hofbauer cells: 558.3;Leydig cells: 324.3;Melanocytes: 343.3;Proximal enterocytes: 580.6;Skeletal myocytes: 288.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 32.2;eosinophil: 43.0;plasmacytoid DC: 23.8" "Group enriched" "Detected in many" 22 "dendritic cells: 23.8;granulocytes: 43.0" "Cell line enhanced" "Detected in many" "ASC diff: 383.5;HMC-1: 263.7;SuSa: 333.9;WM-115: 448.8" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (3.00e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-1)" "unprognostic (4.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.28e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-1)" "unprognostic (4.33e-2)" "unprognostic (7.70e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.83e-2)" "unprognostic (5.45e-2)" "unprognostic (2.88e-1)" "unprognostic (1.08e-2)" 275.6 45.4 113.6 55.1 161.0 4.9 184.5 153.2 140.7 192.2 77.9 212.2 41.7 142.1 36.5 68.2 163.4 106.5 167.6 113.5 129.0 53.5 11.7 208.4 27.8 163.3 144.2 102.9 22.8 10.8 26.3 201.9 159.9 81.2 74.7 6.5 77.5 80.6 252.4 112.7 239.1 122.0 135.0 27.9 96.2 20.7 141.1 17.3 95.3 127.0 21.8 208.9 157.4 216.7 7.0 44.1 61.9 62.2 383.5 167.1 12.6 60.5 68.8 58.7 38.0 48.7 1.1 0.1 7.0 172.3 22.7 0.7 74.0 1.1 15.4 0.2 13.9 4.3 76.7 17.2 201.8 0.1 263.7 126.9 1.1 32.6 1.8 72.1 66.1 2.8 24.5 0.8 33.2 6.1 0.2 2.0 3.5 4.0 74.7 22.0 39.3 0.0 44.6 4.8 0.1 40.6 16.6 0.6 134.2 333.9 0.2 0.5 81.4 12.7 45.7 216.9 62.0 0.5 0.1 0.3 84.7 0.1 448.8 32.2 1.4 43.0 0.0 0.9 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.1 0.2 0.1 0.2 23.8 0.0 0.9 113.6 161.0 153.2 140.7 113.5 129.0 163.3 144.2 159.9 135.0 141.1 216.7 86.6 28.9 11.5 50.9 2.8 90.1 6.7 6.1 9.6 1.4 43.0 82.7 68.4 4.3 7.4 0.0 0.0 8.8 2.5 9.1 3.9 4.5 17.7 20.1 118.6 148.0 4.8 10.1 3.7 3.3 23.1 404.1 2.6 11.0 119.7 25.0 88.5 0.9 558.3 0.0 1.8 23.8 0.0 23.4 116.8 11.0 324.3 93.0 343.3 29.0 11.8 61.6 0.0 46.8 217.1 1.7 25.2 246.4 1.9 4.9 580.6 0.7 3.0 2.2 230.1 288.8 141.1 3.0 4.8 3.0 103.0 19.0 8.7 49.2 17.9 5.2 PMS2 "H_DJ0042M02.9, HNPCC4, MLH4, PMSL2" ENSG00000122512 "PMS1 homolog 2, mismatch repair system component" P54278 7 5970925-6009106 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010235, HPA066490, HPA070310" Approved Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "CAB010235: AB_2167281, HPA066490: AB_2685677, HPA070310: AB_2686250" "unprognostic (5.13e-2)" "unprognostic (6.55e-3)" "unprognostic (1.54e-1)" "unprognostic (1.43e-3)" "unprognostic (5.14e-2)" "unprognostic (1.29e-1)" "unprognostic (7.36e-2)" "unprognostic (1.02e-1)" "unprognostic (7.43e-2)" "unprognostic (2.35e-1)" "unprognostic (1.86e-1)" "unprognostic (7.38e-2)" "prognostic favorable (1.23e-5)" "unprognostic (5.31e-2)" "unprognostic (2.01e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-2)" 5.3 5.1 6.7 5.3 7.2 5.8 6.5 6.3 7.6 4.8 2.8 4.8 5.7 4.9 5.0 5.3 5.7 4.0 4.1 7.4 5.8 10.4 4.7 4.4 8.4 5.3 5.6 5.7 3.9 11.0 4.6 4.8 5.5 5.2 4.7 8.4 5.7 5.5 4.5 11.9 5.3 5.3 4.4 5.9 5.0 4.0 5.2 8.8 9.2 3.5 8.9 5.1 4.9 7.0 15.1 16.7 12.9 32.2 9.0 13.6 10.9 7.8 5.8 6.6 5.6 14.0 9.9 28.2 8.7 10.9 17.2 19.6 19.2 6.6 8.0 11.3 7.2 12.0 12.5 10.1 15.9 15.8 9.4 15.1 14.8 5.4 22.3 11.4 13.7 15.2 22.9 12.6 11.9 15.5 5.2 17.1 13.3 7.6 9.6 16.3 15.3 14.0 16.4 11.0 11.9 25.7 13.3 23.0 16.2 18.0 27.1 11.8 12.4 9.3 21.2 14.2 14.6 19.8 32.8 27.5 7.2 15.3 22.9 5.0 2.9 1.9 4.5 4.1 4.9 3.4 3.5 3.8 3.0 3.4 4.4 3.4 1.4 2.3 1.8 3.1 3.4 3.4 6.7 7.2 6.3 7.6 7.4 5.8 5.3 5.6 5.5 4.4 5.2 7.0 12.2 12.8 8.2 11.4 13.6 5.0 9.3 10.9 15.9 13.2 10.7 11.3 3.2 12.8 9.7 11.0 22.9 9.4 15.2 1.8 35.2 5.5 9.9 11.0 14.6 10.1 5.4 8.4 14.0 3.3 6.3 6.6 8.2 11.8 5.1 11.4 7.9 7.6 5.2 30.3 12.2 2.2 10.2 7.1 5.9 6.6 12.8 6.3 7.2 5.6 8.7 7.8 20.6 3.5 8.3 4.7 2.6 10.1 9.6 12.6 2.2 39.5 9.3 14.3 26.3 10.0 8.0 34.5 11.7 10.5 8.1 12.7 11.4 11.9 2.6 11.1 PNMT PENT ENSG00000141744 "Phenylethanolamine N-methyltransferase" P11086 17 39667981-39670475 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 158.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 20.1;Breast myoepithelial cells: 15.1;Cardiomyocytes: 13.4;Endometrial ciliated cells: 24.0;Erythroid cells: 16.6;Hepatic stellate cells: 27.5;Skeletal myocytes: 48.0" "Group enriched" "Detected in many" 5 "breast cancer: 7.7;cervical cancer: 27.0;urothelial cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 5.3;K-562: 12.8;NB-4: 24.1;NTERA-2: 4.5;SCLC-21H: 6.4;SH-SY5Y: 5.8" "Region enhanced" "Detected in single" "basal ganglia: 1.4" "Not detected" "Not detected" "CAB017029, HPA043412, HPA051005" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017029: , HPA043412: AB_2630373, HPA051005: AB_2681306" "unprognostic (1.50e-1)" "unprognostic (3.74e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (3.95e-5)" "unprognostic (4.27e-2)" "unprognostic (3.02e-1)" "unprognostic (2.98e-2)" "unprognostic (5.75e-2)" "unprognostic (5.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (1.52e-4)" "unprognostic (1.58e-1)" "unprognostic (1.97e-1)" "unprognostic (4.72e-2)" "unprognostic (1.87e-2)" 5.3 158.3 15.9 0.2 28.9 2.1 8.4 17.3 16.3 7.6 7.4 4.2 0.5 4.4 1.4 3.0 9.0 0.3 22.6 9.9 17.0 3.7 0.5 8.9 0.3 17.3 22.7 3.0 1.7 7.4 30.7 3.2 20.0 8.5 0.0 0.1 3.2 21.3 21.1 3.1 7.2 0.2 10.8 2.1 6.9 4.5 25.7 0.1 1.8 17.5 0.0 6.5 5.9 11.7 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.9 5.3 0.2 0.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 24.1 4.5 0.5 0.1 0.1 0.0 0.3 0.0 0.0 6.4 5.8 0.1 2.3 0.2 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 15.9 28.9 17.3 16.3 9.9 17.0 17.3 22.7 20.0 10.8 25.7 11.7 3.1 0.0 0.0 1.0 0.5 0.5 0.7 0.0 0.0 0.3 20.1 15.1 13.4 1.5 0.0 5.5 0.0 0.1 1.1 0.1 1.9 0.0 0.7 24.0 2.6 5.0 3.0 16.6 0.5 0.0 0.9 1.1 0.0 9.0 0.0 0.7 27.5 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 1.5 2.1 0.2 0.0 1.0 0.0 3.5 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.2 0.1 0.1 0.0 0.5 0.0 48.0 0.8 1.0 2.3 0.0 0.4 0.0 11.0 0.0 0.3 1.8 POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418018 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 51.3;Spermatogonia: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004375, HPA046524" Supported Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004375: AB_675487, HPA046524: AB_2679684" "unprognostic (2.45e-1)" "unprognostic (7.02e-3)" "unprognostic (1.59e-1)" "unprognostic (4.35e-2)" "unprognostic (2.55e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.87e-6)" "unprognostic (4.12e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (5.08e-1)" "unprognostic (3.92e-3)" "unprognostic (4.01e-3)" "unprognostic (1.28e-2)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "unprognostic (3.70e-2)" 5.6 5.1 3.2 9.2 3.7 26.3 6.3 4.5 3.8 7.6 2.5 8.9 5.4 8.4 0.4 10.7 6.5 2.1 5.8 2.7 2.7 6.5 6.4 9.5 11.2 5.1 3.7 7.1 7.9 2.3 4.7 5.9 4.1 6.1 2.2 1.9 7.4 2.6 5.6 9.2 10.1 2.3 3.5 12.8 6.2 13.3 4.1 11.0 9.8 1.5 5.2 5.9 7.7 4.4 52.1 77.9 27.9 22.4 3.0 2.8 45.6 34.0 9.6 30.0 34.9 42.4 39.2 84.6 19.4 7.1 13.9 45.1 27.4 25.1 6.8 64.4 145.0 66.1 73.0 54.6 3.7 67.0 57.7 6.4 7.1 26.1 6.5 6.0 14.2 58.2 77.4 54.3 9.1 40.6 92.2 110.6 48.7 25.3 55.4 105.4 62.2 67.7 7.4 44.9 39.3 38.6 33.0 35.9 8.8 10.1 21.1 50.7 17.4 21.4 70.7 22.0 56.5 60.0 91.3 76.3 21.2 66.9 20.8 1.3 4.3 1.5 4.3 5.6 4.0 6.0 4.0 3.5 3.9 5.4 4.0 3.9 0.6 4.2 6.9 7.1 3.1 4.0 3.2 3.7 4.5 3.8 2.7 2.7 5.1 3.7 4.1 3.5 4.1 4.4 3.5 3.2 3.9 0.7 8.7 6.4 2.3 3.5 3.4 4.0 4.3 5.3 3.4 2.8 3.8 3.7 6.2 19.2 3.8 12.2 0.0 4.8 1.9 2.8 1.6 3.4 7.2 15.2 1.2 4.0 15.0 4.1 3.1 3.0 0.0 9.5 1.1 2.2 15.1 0.0 0.9 7.4 0.0 5.7 5.3 1.9 3.1 5.8 5.4 1.0 4.8 1.2 6.2 1.5 2.2 4.7 51.3 5.3 10.6 2.8 6.3 2.8 3.0 4.3 0.0 3.5 4.0 11.5 25.6 5.5 5.3 7.7 5.4 3.4 14.3 1.3 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687376 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 46.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA058210: AB_2683639, HPA067385: AB_2685830" "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.0 2.9 0.2 6.1 0.2 24.7 6.0 4.1 1.1 6.4 0.3 7.3 6.5 5.4 2.1 7.0 6.2 3.1 4.3 1.6 0.0 3.0 8.6 5.0 7.2 0.3 0.1 7.8 6.5 2.6 2.7 5.3 0.3 6.4 6.3 2.4 6.1 3.3 7.5 13.2 8.5 3.7 0.1 16.2 8.0 16.2 0.5 15.7 4.7 3.0 7.1 6.1 6.2 0.3 25.3 33.3 48.7 22.0 10.2 7.6 39.9 26.0 11.7 30.3 21.8 38.3 14.5 28.7 10.2 14.1 11.6 33.6 35.4 16.7 18.8 13.3 41.2 45.4 45.7 15.2 1.9 37.2 24.9 5.5 6.0 31.8 10.5 8.1 10.8 35.1 53.4 15.7 14.9 33.3 61.8 46.8 36.9 9.3 18.5 48.0 27.6 13.0 6.9 40.8 40.6 22.0 30.0 22.7 4.7 23.4 35.0 19.1 9.9 26.5 24.7 20.6 25.9 20.3 14.5 44.8 14.7 26.3 19.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 4.1 1.1 1.6 0.0 0.3 0.1 0.3 0.1 0.5 0.3 3.2 0.0 6.7 7.5 4.0 5.7 3.8 3.0 4.0 8.7 7.8 6.7 6.9 1.5 1.6 1.8 0.0 8.8 5.6 18.8 0.0 2.3 8.2 3.2 3.8 4.9 7.2 14.9 13.6 3.3 10.8 5.1 11.2 6.8 2.5 16.2 8.9 10.5 13.2 0.0 7.6 9.1 2.0 6.9 5.4 9.7 6.8 2.9 5.4 4.7 1.6 2.6 2.1 3.5 2.9 2.6 6.0 3.4 6.3 4.0 4.1 1.0 1.9 6.1 26.3 7.0 6.1 46.6 18.2 5.8 7.7 4.0 5.8 2.9 10.9 2.8 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favorable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.1 0.2 0.0 1.6 0.1 6.0 0.4 1.0 0.2 0.2 0.0 1.2 1.2 0.2 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 2.0 0.0 0.3 0.0 0.0 1.4 0.9 0.4 0.0 0.8 0.5 2.2 0.0 4.5 0.0 0.0 2.3 0.3 0.5 0.0 18.2 12.1 10.2 7.2 0.9 1.2 9.2 8.5 3.2 9.7 12.9 9.8 6.6 21.5 3.7 4.6 11.7 14.0 12.2 5.4 16.4 6.3 6.7 13.8 8.0 6.1 0.1 15.1 12.1 0.2 0.4 8.9 5.4 1.7 4.9 7.9 9.3 15.9 10.3 7.1 13.7 8.8 9.7 5.5 5.9 11.4 12.2 7.6 3.1 10.3 5.5 5.0 9.8 5.2 3.4 8.8 4.8 14.8 3.8 8.6 11.2 3.4 11.1 8.0 6.9 21.8 4.1 11.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.6 0.7 0.9 0.5 0.6 0.0 0.9 0.6 0.6 1.6 0.0 2.0 0.0 0.0 3.1 0.6 1.6 0.0 0.1 0.4 0.9 1.0 0.5 0.0 16.4 9.5 0.0 3.3 1.2 4.6 1.0 0.0 12.6 0.0 0.2 2.3 0.0 7.8 1.6 2.0 1.3 1.2 0.7 0.3 1.7 0.0 1.0 0.6 0.4 0.0 1.5 1.3 0.2 1.2 0.0 12.2 0.5 0.2 0.1 2.4 0.2 0.0 0.1 1.0 6.8 3.4 4.9 0.1 0.3 1.8 0.9 3.2 0.8 POMC "ACTH, CLIP, LPH, MSH, NPP, POC" ENSG00000115138 Proopiomelanocortin P01189 2 25160853-25168903 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Endorphin, Hormone" "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 903 "pituitary gland: 34360.0" "Cell type enhanced" "Detected in many" "Early spermatids: 119.8;Late spermatids: 352.6;Spermatocytes: 83.0" "Cancer enriched" "Detected in many" 6 "testis cancer: 18.5" "Group enriched" "Detected in all" 6 "hypothalamus: 38.0;thalamus: 13.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;THP-1: 2.1" "Region enriched" "Detected in all" 7 "hypothalamus: 44.0" "Region enriched" "Detected in all" 5 "hypothalamus: 88.1" "CAB002762, HPA046135, HPA063644, CAB079881" Enhanced "Secreted to blood" NA NA 380000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "CAB002762: , CAB079881: , HPA046135: AB_2679552, HPA063644: AB_2685071" "unprognostic (8.02e-2)" "unprognostic (1.47e-2)" "unprognostic (4.78e-2)" "unprognostic (1.96e-3)" "unprognostic (3.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.30e-2)" "unprognostic (8.74e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.70e-4)" "unprognostic (8.02e-2)" "unprognostic (4.29e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (3.84e-2)" 6.1 19.1 2.7 1.2 2.8 1.1 3.5 3.2 4.4 3.0 2.2 6.9 0.4 3.1 0.3 13.7 2.2 0.2 12.1 2.3 38.0 4.9 12.9 3.5 1.1 4.5 3.3 5.0 22.6 0.1 34360.0 1.2 3.7 5.0 0.0 0.2 5.8 0.3 5.7 35.7 4.8 0.1 4.0 11.1 15.5 25.7 13.1 1.2 8.4 5.2 0.4 2.5 3.7 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 12.6 8.6 11.5 13.2 9.1 16.8 8.8 11.3 15.9 17.4 11.6 12.6 3.8 18.2 8.0 27.9 10.5 9.7 2.7 2.8 3.2 4.4 2.3 38.0 4.5 3.3 3.7 4.0 13.1 3.5 22.3 0.0 2.2 1.0 16.1 4.5 2.2 6.9 2.2 2.6 6.1 6.7 2.5 2.8 2.5 0.0 0.0 0.5 24.4 0.2 15.6 7.8 119.8 0.6 4.9 11.6 0.0 28.8 0.3 17.3 6.0 5.2 4.6 0.6 7.0 9.7 15.4 2.0 34.5 6.7 0.6 0.0 6.1 10.9 7.9 352.6 4.7 17.2 17.8 1.9 8.5 11.5 15.5 0.0 0.3 10.1 1.1 13.2 17.8 4.1 0.1 3.9 0.7 7.5 13.1 4.6 3.8 83.0 27.3 1.6 5.5 0.4 14.9 12.9 0.6 3.8 PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324532 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "liver: 531.8" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 440.0" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" NA NA 96000000000 17000000000 "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favorable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" 0.0 4.1 0.6 0.0 0.5 0.0 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.5 0.6 0.2 531.8 0.1 0.0 0.5 0.5 0.6 0.1 0.0 0.8 0.0 0.5 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.3 0.6 5.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.6 0.5 0.6 0.5 0.5 0.5 0.3 0.6 0.6 0.0 0.0 1.5 7.2 1.1 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.6 18.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.4 3.0 13.5 0.2 0.2 0.0 0.2 0.0 0.3 0.0 0.1 8.9 440.0 0.0 0.0 0.2 0.2 0.0 13.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 1.6 0.5 0.4 0.2 0.0 0.1 0.0 0.6 0.5 0.3 0.1 POSTN "OSF-2, periostin, PN" ENSG00000133110 Periostin Q15063 13 37562583-37598844 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 207.2;stomach 1: 174.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 295.7;Breast myoepithelial cells: 158.1;Endothelial cells: 134.6;Fibroblasts: 191.5;Smooth muscle cells: 151.5" "Cancer enhanced" "Detected in all" "breast cancer: 231.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTEC/SVTERT24-B: 490.2;SuSa: 440.5;U-138 MG: 619.3;U-2197: 427.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 87.9" HPA012306 Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to extracellular matrix" NA NA 660000000 "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Nucleoplasm "HPA012306: AB_1854827" "unprognostic (7.73e-2)" "unprognostic (1.44e-3)" "unprognostic (2.19e-2)" "unprognostic (2.57e-2)" "unprognostic (4.73e-2)" "unprognostic (2.22e-2)" "unprognostic (4.19e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (3.05e-3)" "unprognostic (7.10e-2)" "unprognostic (1.32e-2)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.83e-7)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (8.32e-3)" 71.4 5.2 4.5 23.8 0.1 0.3 84.0 0.0 4.4 20.3 2.9 61.3 5.1 53.2 13.0 20.5 83.5 64.3 83.2 3.0 0.0 28.1 13.0 45.1 12.8 0.9 0.0 3.6 2.2 21.6 2.4 60.9 2.0 16.1 84.9 0.0 17.7 44.8 10.6 207.2 15.0 66.6 0.0 1.1 174.6 3.4 0.1 5.8 19.1 29.9 3.9 91.4 10.7 0.4 0.0 0.0 71.0 1.6 85.0 51.0 0.2 23.1 0.0 5.5 0.7 0.0 1.4 0.1 0.0 18.7 0.1 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.0 14.2 0.2 0.1 90.8 0.0 490.2 1.9 15.9 0.7 0.0 0.0 0.0 11.8 0.0 0.3 0.4 4.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.4 0.2 0.1 0.6 0.0 440.5 0.9 0.0 0.0 619.3 0.3 427.2 3.4 0.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.0 4.4 3.0 0.0 0.9 0.0 2.0 0.0 0.1 0.4 46.7 6.4 10.6 0.7 0.3 295.7 1.3 51.5 0.0 0.0 2.9 158.1 22.8 0.0 18.7 0.0 0.0 2.5 1.0 0.0 0.0 0.0 0.5 0.5 9.8 134.6 0.0 0.0 1.5 0.0 0.2 191.5 0.0 0.3 3.8 0.0 22.5 0.6 3.7 0.0 36.8 0.0 24.4 0.0 27.0 1.1 6.5 0.8 30.2 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.7 0.4 0.4 0.0 0.0 5.6 0.0 0.0 0.7 151.5 1.3 0.9 0.2 48.4 3.4 2.3 49.3 0.0 0.3 POT1 "DKFZp586D211, hPot1" ENSG00000128513 "Protection of telomeres 1" Q9NUX5 7 124822386-124929983 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 41.5;Oligodendrocytes: 66.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068538 Supported Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA068538: AB_2686001" "unprognostic (1.39e-3)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (5.71e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.38e-3)" "unprognostic (7.88e-2)" "unprognostic (2.26e-2)" "unprognostic (1.51e-1)" "unprognostic (2.48e-2)" "unprognostic (9.89e-2)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.75e-2)" "unprognostic (4.77e-3)" "unprognostic (7.42e-2)" 5.6 5.7 3.2 5.7 3.8 4.1 10.4 3.7 3.6 7.9 4.0 5.6 4.5 9.5 6.1 4.5 8.1 6.0 6.2 3.2 4.2 9.7 9.9 6.1 8.8 3.9 3.4 10.1 5.3 9.8 6.4 6.9 4.1 7.1 6.4 9.9 3.9 6.7 3.2 4.1 4.2 7.2 3.8 8.1 5.8 13.8 3.2 13.0 12.9 4.4 9.6 7.7 4.5 6.1 24.0 6.9 14.0 9.9 9.2 16.2 10.3 12.1 14.9 14.3 19.7 7.3 25.9 24.4 8.5 11.1 23.6 9.5 14.8 15.0 21.7 21.4 17.5 18.9 10.3 3.2 15.4 22.6 12.4 13.1 13.6 12.8 21.8 14.5 16.6 10.1 38.1 51.9 15.0 4.1 29.8 12.5 17.4 13.2 14.1 19.1 14.0 27.5 9.9 9.8 13.9 16.6 18.7 19.8 15.6 20.3 8.0 12.3 8.4 14.3 5.5 19.1 17.1 23.2 27.0 39.8 20.4 23.6 22.7 0.6 2.2 1.0 2.3 2.3 4.3 3.2 2.6 3.0 2.5 2.5 4.3 3.0 0.4 3.7 1.8 2.2 2.8 1.9 3.2 3.8 3.7 3.6 3.2 4.2 3.9 3.4 4.1 3.8 3.2 6.1 9.7 6.4 4.1 36.9 10.1 4.6 6.7 5.5 13.1 9.2 7.1 7.1 8.8 8.6 3.6 12.9 10.4 7.0 8.0 1.5 19.6 5.0 19.3 4.3 6.9 7.1 9.0 16.0 34.7 4.5 8.0 6.9 8.2 4.2 3.8 9.4 7.1 10.5 6.3 8.4 41.5 4.0 2.0 10.9 7.0 8.3 8.7 8.7 16.0 24.4 5.6 12.6 4.1 37.2 66.8 3.8 1.7 4.5 7.6 2.8 0.8 11.2 4.9 10.0 0.0 5.4 6.3 35.2 14.4 7.6 2.6 4.5 8.5 4.8 4.9 3.5 POTEF "A26C1B, POTE2alpha, POTEACTIN" ENSG00000196604 "POTE ankyrin domain family member F" A5A3E0 2 130073535-130129222 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 1.6;testis: 1.7" "Cell type enhanced" "Detected in some" "Melanocytes: 1.8;NK-cells: 1.0;Smooth muscle cells: 1.3;Spermatocytes: 2.2;Spermatogonia: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;BEWO: 2.0;CACO-2: 2.3;MCF7: 1.8;U-2 OS: 5.6;U-266/70: 2.7" "HPA041264, HPA041271, HPA043260" Uncertain NA NA 1900000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (8.13e-3)" "unprognostic (1.44e-2)" "unprognostic (2.90e-2)" "unprognostic (1.16e-1)" "unprognostic (3.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.50e-1)" "unprognostic (1.02e-1)" "unprognostic (4.48e-1)" "unprognostic (1.05e-2)" "unprognostic (9.35e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 2.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.1 2.7 0.8 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 1.6 0.1 0.2 0.0 0.0 0.2 1.6 0.9 0.5 0.5 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.3 2.2 1.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 POU2AF1 "BOB1, OBF1" ENSG00000110777 "POU class 2 homeobox associating factor 1" Q16633 11 111352255-111455630 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 119.4;stomach 1: 40.1" "Cell type enriched" "Detected in many" 4 "Plasma cells: 566.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 33.5;naive B-cell: 24.0" "Lineage enriched" "Detected in many" 9 "B-cells: 33.5" "Group enriched" "Detected in many" 4 "Daudi: 307.2;Karpas-707: 339.3;U-266/70: 326.6;U-266/84: 159.9;U-698: 610.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011193 Enhanced NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB011193: AB_532299" "prognostic favorable (1.68e-4)" "prognostic favorable (1.63e-4)" "unprognostic (1.04e-2)" "unprognostic (5.50e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.59e-4)" "unprognostic (2.09e-1)" "unprognostic (3.63e-3)" "unprognostic (7.15e-2)" "unprognostic (2.52e-2)" "unprognostic (1.34e-1)" "unprognostic (4.81e-2)" "unprognostic (8.51e-8)" "unprognostic (2.35e-1)" "unprognostic (3.90e-1)" "unprognostic (7.14e-3)" "unprognostic (1.23e-1)" 1.9 1.2 6.4 49.0 4.9 8.1 5.6 4.2 7.0 1.7 20.3 15.7 22.2 1.5 1.3 2.9 1.3 4.7 1.4 5.4 3.6 1.4 1.4 3.3 99.3 6.2 6.1 1.1 0.6 0.3 0.1 2.8 7.2 1.8 13.4 6.5 12.9 1.9 1.8 1.1 38.6 1.2 2.7 79.5 40.1 1.6 5.4 9.6 2.8 0.3 119.4 9.3 1.9 7.3 0.9 0.9 0.3 0.4 5.6 5.2 1.0 0.2 0.1 0.1 0.1 1.1 0.3 307.2 0.7 0.3 0.2 0.8 0.9 0.4 0.1 0.9 0.2 0.5 1.0 1.1 0.1 0.6 1.7 0.2 0.3 0.3 0.6 0.5 0.3 3.4 11.8 339.3 0.3 0.8 1.5 1.6 0.4 0.5 0.5 65.3 0.7 83.0 0.2 0.8 0.6 6.1 0.7 0.3 0.2 2.4 1.3 0.9 2.7 0.5 3.1 0.6 0.5 326.6 159.9 610.8 0.4 0.7 0.5 3.8 0.2 0.6 0.3 0.2 0.2 33.5 0.5 0.2 0.1 24.0 0.4 0.2 1.6 0.5 0.4 0.3 1.2 1.2 6.4 4.9 4.2 7.0 5.4 3.6 6.2 6.1 7.2 2.7 5.4 7.3 0.0 0.0 3.6 0.3 131.3 0.3 7.1 12.3 0.0 0.0 0.0 0.9 1.9 10.0 20.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 8.4 24.9 0.6 0.2 3.0 6.6 0.1 5.7 0.0 0.8 4.6 0.5 0.0 0.1 0.7 2.4 0.1 0.0 0.1 0.7 2.0 0.6 0.4 10.9 0.3 0.8 8.8 1.0 0.3 0.0 1.0 0.0 4.6 0.4 1.2 0.4 566.8 1.2 0.0 0.4 65.0 0.0 0.0 0.1 1.0 6.3 1.8 0.8 0.0 0.0 4.2 0.0 0.8 8.4 POU2F2 "OCT2, OTF2" ENSG00000028277 "POU class 2 homeobox 2" P09086 19 42086110-42196585 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.1" "Cell type enhanced" "Detected in many" "B-cells: 225.5;Kupffer cells: 119.6;Langerhans cells: 104.4;Macrophages: 105.0;monocytes: 137.6;Plasma cells: 96.7;Spermatocytes: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 94.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 52.3;Daudi: 113.0;hTEC/SVTERT24-B: 42.7;U-266/70: 75.5;U-266/84: 80.2;U-698: 88.4;U-87 MG: 41.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002513, HPA049056, HPA062096, HPA064404, HPA073998" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB002513: AB_442118, HPA049056: AB_2732550, HPA062096: AB_2684681, HPA064404: AB_2685259, HPA073998: " "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-2)" "unprognostic (8.89e-2)" "unprognostic (6.77e-2)" "unprognostic (1.44e-2)" "unprognostic (1.62e-2)" "unprognostic (3.34e-1)" "unprognostic (8.39e-2)" "unprognostic (2.09e-1)" "unprognostic (1.52e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (7.57e-11)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (2.61e-2)" "unprognostic (1.54e-1)" 2.6 2.8 6.1 28.0 5.9 8.4 1.7 15.5 10.6 1.1 3.8 4.3 3.1 1.2 1.5 2.0 1.6 3.4 0.8 5.8 15.4 1.4 2.0 3.8 52.1 8.0 9.1 0.8 1.7 0.3 2.0 3.8 9.4 3.0 3.0 1.9 2.6 3.1 1.1 1.4 14.0 2.9 5.8 27.5 5.0 9.2 14.0 6.5 1.5 0.5 48.3 7.1 1.2 6.7 0.9 1.5 1.8 0.1 0.0 2.9 0.5 8.2 52.3 5.1 10.0 0.5 1.4 113.0 2.8 2.9 0.9 1.0 0.6 8.6 23.2 0.3 0.5 2.7 0.3 0.1 0.6 1.1 2.2 2.2 1.6 42.7 2.8 0.4 3.2 2.4 1.3 25.4 1.1 0.8 0.3 6.1 0.4 0.2 0.6 1.3 0.2 0.4 0.2 0.5 1.8 0.8 0.4 0.7 0.8 0.7 0.1 14.1 3.9 22.0 2.3 0.2 1.1 75.5 80.2 88.4 41.3 2.8 3.1 2.6 28.3 0.5 3.1 51.5 2.7 29.3 4.4 4.0 20.9 33.0 2.3 3.3 4.3 1.7 94.9 3.4 7.2 14.4 6.1 5.9 15.5 10.6 5.8 15.4 8.0 9.1 9.4 5.8 14.0 6.7 2.7 0.0 7.0 0.7 225.5 7.8 8.3 14.1 4.6 63.5 7.2 7.6 3.7 2.8 3.2 0.0 6.2 0.9 29.3 2.8 0.0 1.4 15.2 4.0 1.1 7.3 9.5 10.7 19.7 2.8 0.8 2.7 1.5 8.5 6.3 0.5 4.2 1.1 49.5 1.7 10.0 1.6 4.1 119.6 104.4 9.8 0.9 105.0 8.8 32.8 137.6 1.9 37.0 4.5 1.0 3.5 0.1 0.4 96.7 3.8 2.8 0.4 2.4 6.6 0.0 1.7 5.0 75.1 28.8 13.3 8.8 3.7 31.7 0.6 1.0 5.0 POU5F1 "MGC22487, OCT3, Oct4, OTF3" ENSG00000204531 "POU class 5 homeobox 1" Q01860 6 31164337-31180731 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.9;Glandular and luminal cells: 67.8" "Cancer enriched" "Detected in many" 34 "testis cancer: 355.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 51 "SuSa: 287.4" "Not detected" "Not detected" "CAB025600, CAB026380, HPA058267, CAB079773" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB025600: , CAB026380: , CAB079773: AB_2687916, HPA058267: AB_2683659" "unprognostic (3.25e-2)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-2)" "unprognostic (2.11e-2)" "unprognostic (2.62e-2)" "unprognostic (2.27e-1)" "unprognostic (2.59e-1)" "unprognostic (9.27e-2)" "unprognostic (2.27e-2)" "unprognostic (4.79e-2)" "unprognostic (1.19e-3)" "unprognostic (1.38e-1)" "unprognostic (1.35e-1)" "unprognostic (3.86e-2)" "prognostic favorable (2.04e-5)" 1.1 0.3 1.2 1.0 1.0 1.5 1.2 1.5 1.2 6.3 0.4 4.9 4.3 2.3 2.4 1.8 7.1 2.1 3.3 1.0 0.7 16.5 8.0 3.7 1.0 1.3 0.8 0.5 13.0 0.0 0.3 0.2 1.1 7.6 1.1 0.7 0.8 2.4 1.0 2.2 8.0 0.3 0.2 2.0 10.1 1.3 1.3 0.2 0.9 0.3 0.3 10.2 2.0 1.9 3.6 1.8 0.4 0.7 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 1.3 0.3 5.6 0.1 0.4 2.9 0.7 3.1 0.0 0.6 1.4 0.6 3.3 2.5 0.2 0.9 0.8 0.3 0.6 0.3 0.9 0.2 0.0 0.7 0.1 1.0 1.0 0.2 0.3 1.0 2.9 0.6 0.1 0.8 0.6 0.7 4.8 3.8 0.6 0.1 1.0 0.2 0.3 287.4 0.6 0.4 0.0 0.7 0.5 1.8 0.3 1.3 1.3 1.6 0.5 1.3 0.5 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.2 0.1 0.3 0.0 0.1 1.2 1.0 1.5 1.2 1.0 0.7 1.3 0.8 1.1 0.2 1.3 1.9 1.0 0.0 1.1 0.0 0.9 5.2 2.7 5.3 2.8 0.5 0.7 0.8 0.4 10.0 2.3 9.2 2.1 0.0 0.1 9.2 0.0 6.7 0.0 27.9 5.9 1.2 1.2 0.0 0.2 6.6 0.1 0.7 11.2 67.8 0.0 0.1 0.4 2.4 0.1 0.0 0.1 6.4 2.0 0.0 1.5 0.2 0.0 0.7 1.8 1.0 0.7 0.1 1.0 0.5 0.1 12.6 12.5 0.7 0.2 5.6 10.1 2.0 1.6 1.0 0.0 1.4 1.2 0.1 0.8 0.8 3.8 0.1 0.8 0.0 4.1 4.3 PPA2 FLJ20459 ENSG00000138777 "Inorganic pyrophosphatase 2" Q9H2U2 4 105369077-105474067 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Approved Mitochondria NA NA 150000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA030888: AB_2673646, HPA031671: AB_10603986, HPA031672: AB_2673988" "prognostic unfavorable (2.98e-4)" "unprognostic (5.64e-2)" "prognostic favorable (6.60e-4)" "unprognostic (9.26e-3)" "unprognostic (2.93e-2)" "unprognostic (5.10e-2)" "unprognostic (1.15e-1)" "unprognostic (2.44e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "unprognostic (9.54e-2)" "prognostic favorable (1.27e-11)" "unprognostic (3.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" 7.4 12.8 23.8 9.0 24.6 22.0 12.0 24.3 53.7 7.4 29.5 17.4 14.2 7.4 12.5 10.8 8.4 8.0 27.5 23.7 26.3 20.7 14.8 7.5 8.3 24.4 24.3 5.8 11.8 11.7 7.7 7.4 24.5 13.3 14.0 13.6 13.8 5.7 27.6 12.2 13.8 6.8 24.0 9.9 12.6 6.3 25.4 7.0 11.5 35.5 8.7 8.1 6.7 26.6 20.6 8.5 18.5 32.3 11.3 9.1 12.9 10.2 15.7 14.6 9.9 22.2 30.4 15.6 14.5 9.7 11.3 9.5 39.2 18.7 17.0 23.6 11.8 13.5 13.7 19.9 9.3 36.7 13.6 9.7 19.6 9.9 7.9 15.4 14.6 28.4 22.3 22.0 12.5 26.2 32.5 26.6 13.9 42.4 28.3 28.2 10.9 17.9 49.7 14.7 17.8 10.7 7.8 48.9 19.0 10.7 24.8 32.1 6.9 9.2 19.2 8.9 20.0 19.0 27.3 18.4 17.5 18.6 14.1 27.0 20.9 15.4 21.0 30.1 18.6 28.5 21.7 23.7 49.9 22.6 21.1 23.9 9.5 36.4 26.4 25.9 23.4 23.5 23.8 24.6 24.3 53.7 23.7 26.3 24.4 24.3 24.5 24.0 25.4 26.6 26.7 9.6 67.3 86.2 37.6 50.0 82.4 205.0 38.1 29.7 64.8 40.9 63.3 45.8 126.2 33.1 16.7 119.0 25.9 73.3 264.1 114.0 113.7 42.3 35.3 36.3 65.7 70.2 138.2 120.1 98.5 31.1 37.2 42.3 45.6 26.4 24.3 64.2 83.5 21.9 134.6 104.6 142.4 42.9 86.1 126.4 27.7 47.1 76.5 74.9 50.5 39.2 30.9 169.9 145.7 65.0 90.4 32.4 41.9 68.1 112.2 285.4 90.7 22.6 39.5 46.3 43.6 50.8 10.8 59.1 57.7 84.7 34.3 72.1 138.0 94.6 PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSG00000132170 "Peroxisome proliferator activated receptor gamma" P37231 3 12287368-12434356 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 165.1" "Cell type enhanced" "Detected in many" "Adipocytes: 284.1;Extravillous trophoblasts: 217.8;Granulosa cells: 232.9;Urothelial cells: 239.6" "Cancer enhanced" "Detected in all" "urothelial cancer: 33.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 198.7;ASC TERT1: 113.7;BEWO: 247.5;CAPAN-2: 111.6;HSkMC: 118.9;PC-3: 112.0;RT4: 157.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB004282, HPA051239, HPA063663" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "CAB004282: AB_628115, HPA051239: AB_2681400, HPA063663: AB_2685081" "unprognostic (7.35e-3)" "unprognostic (3.27e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-2)" "unprognostic (2.41e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (3.41e-5)" "unprognostic (9.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.59e-8)" "unprognostic (1.51e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-3)" "prognostic favorable (5.52e-5)" 165.1 3.9 4.0 8.7 3.0 3.0 74.3 3.2 4.7 9.7 0.6 48.7 23.6 7.0 1.2 6.2 7.0 10.5 14.6 4.0 2.7 14.3 17.1 28.5 4.9 3.7 3.5 14.5 2.8 7.9 0.5 43.6 3.4 5.5 40.6 1.0 5.7 1.7 5.2 6.2 15.1 8.7 3.2 12.0 35.5 6.9 3.5 4.1 13.2 8.1 2.1 67.7 9.1 5.0 44.0 38.6 0.0 0.2 198.7 113.7 247.5 3.7 44.7 5.4 2.1 7.8 111.6 0.0 0.1 4.0 72.9 17.3 14.4 0.7 1.0 106.4 20.3 0.0 8.1 10.3 51.8 0.2 0.1 118.9 9.7 9.8 37.5 20.6 0.7 1.0 0.0 0.0 8.3 11.0 0.1 0.8 0.7 99.2 112.0 0.0 0.0 0.2 30.6 157.5 0.1 1.2 18.8 6.7 2.2 6.7 0.0 34.2 35.0 7.8 10.6 4.6 0.2 0.0 0.1 0.3 3.2 0.5 1.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 3.0 3.2 4.7 4.0 2.7 3.7 3.5 3.4 3.2 3.5 5.0 284.1 3.2 7.2 1.6 0.6 1.0 50.5 0.4 4.6 0.9 1.9 2.8 9.2 1.5 2.5 5.5 0.0 110.4 1.8 93.4 1.9 1.1 4.9 5.2 1.4 26.1 8.4 0.0 39.3 0.7 217.8 12.3 83.1 20.8 8.9 232.9 25.7 3.4 49.9 0.0 74.1 21.3 0.0 19.4 4.8 2.2 4.1 19.1 3.6 38.4 1.8 0.6 0.0 6.6 1.2 17.3 84.1 0.0 1.6 42.1 17.0 14.3 1.5 0.2 13.1 1.9 31.3 10.9 22.8 4.6 1.1 88.9 2.2 0.8 24.5 239.6 PPARGC1A "PGC-1alpha, PGC1, PGC1A, PPARGC1" ENSG00000109819 "PPARG coactivator 1 alpha" Q9UBK2 4 23755041-23904089 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Activator, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.6" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1098.2;Inhibitory neurons: 1704.4;Oligodendrocyte precursor cells: 890.2" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "A-431: 88.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063136 Supported Nucleoplasm NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA063136: AB_2684948" "unprognostic (1.08e-1)" "unprognostic (7.47e-2)" "unprognostic (6.85e-3)" "unprognostic (2.28e-6)" "unprognostic (5.00e-2)" "unprognostic (1.15e-1)" "prognostic favorable (3.35e-6)" "unprognostic (3.04e-1)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (6.77e-2)" "unprognostic (4.58e-2)" "prognostic favorable (1.49e-14)" "unprognostic (3.62e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.07e-3)" 2.3 2.9 4.2 0.6 3.2 0.0 1.6 7.6 13.0 3.3 33.9 7.4 7.6 0.9 1.5 3.3 1.5 2.6 36.3 3.1 10.7 29.0 44.6 3.1 0.2 4.1 4.1 1.2 3.8 38.5 4.8 0.1 2.6 3.3 9.1 4.2 29.3 3.0 29.5 8.2 6.6 1.9 2.4 0.8 4.3 4.5 7.2 2.3 17.7 37.2 0.4 1.1 1.0 4.1 88.6 0.0 1.6 0.0 2.6 0.0 0.0 0.0 1.9 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.8 0.0 4.5 10.7 0.0 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.4 7.6 0.0 0.0 0.7 0.0 12.3 0.1 4.0 0.2 2.8 0.0 3.5 4.2 0.5 1.4 0.0 0.7 0.7 0.0 1.6 8.1 0.1 0.1 1.6 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.2 7.6 13.0 3.1 10.7 4.1 4.1 2.6 2.4 7.2 4.1 2.5 19.2 2.6 240.6 0.9 0.9 4.1 7.4 1.2 7.0 2.7 1.5 90.9 47.1 6.3 36.8 39.6 0.0 0.0 36.0 52.8 12.0 78.3 7.2 1.3 0.8 26.7 0.0 1098.2 0.0 0.0 2.4 4.1 9.7 1.3 0.2 1.1 88.8 0.0 0.0 1704.4 17.0 38.7 2.5 0.3 69.7 0.9 0.6 7.2 24.4 0.1 6.4 0.0 890.2 28.8 0.6 7.3 2.2 1.8 1.4 32.0 26.8 4.8 1.9 0.0 37.1 5.1 0.8 0.6 2.6 1.1 0.0 1.0 1.9 21.9 1.5 PPFIBP1 "hSGT2, hSgt2p, L2, SGT2" ENSG00000110841 "PPFIA binding protein 1" Q86W92 12 27523431-27695564 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 201.3;Endothelial cells: 189.5;Excitatory neurons: 206.1;Oligodendrocytes: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001924, HPA071162" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001924: AB_1079665, HPA071162: " "unprognostic (5.27e-2)" "unprognostic (5.71e-2)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.73e-2)" "unprognostic (6.94e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.11e-4)" "unprognostic (7.33e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.92e-2)" "prognostic favorable (5.11e-7)" "unprognostic (8.54e-2)" "unprognostic (7.54e-2)" "unprognostic (2.64e-1)" "unprognostic (4.09e-2)" 32.4 27.0 22.5 13.7 33.6 3.3 37.9 0.3 29.5 24.0 18.3 25.0 11.9 27.7 11.4 28.6 26.6 20.1 77.0 29.0 10.0 36.3 26.7 39.6 9.3 7.0 14.9 85.2 21.3 17.1 19.6 60.2 11.2 24.7 18.2 5.1 21.6 29.3 25.9 30.4 15.0 31.3 5.9 29.9 25.5 11.9 31.6 18.5 39.0 44.3 10.5 24.4 29.5 22.9 18.8 37.1 29.7 25.5 48.4 133.3 52.9 67.0 75.2 38.6 55.4 98.0 55.9 14.2 75.6 135.7 51.5 46.0 16.3 61.0 69.1 32.3 9.0 31.3 28.3 14.6 21.0 9.8 16.9 104.8 41.3 112.1 114.0 75.2 134.0 18.9 16.7 13.9 138.5 14.4 9.1 2.8 53.4 26.8 28.5 14.6 74.0 5.5 56.6 41.0 2.4 12.1 33.4 17.6 91.3 206.5 22.7 14.3 131.3 107.7 36.0 59.8 68.8 0.2 0.4 1.2 119.7 13.7 173.7 0.9 0.2 0.1 0.3 0.0 0.6 0.3 0.5 0.3 0.3 2.7 0.5 0.5 0.6 0.1 0.1 0.9 0.8 0.2 22.5 33.6 0.3 29.5 29.0 10.0 7.0 14.9 11.2 5.9 31.6 22.9 201.3 99.3 19.8 7.5 9.4 41.0 76.5 42.8 68.3 15.5 19.6 40.3 164.0 10.0 18.3 80.9 4.2 37.2 2.5 8.0 11.7 42.2 3.5 40.2 12.7 189.5 18.6 8.6 206.1 24.8 23.2 74.6 46.9 73.3 3.8 132.8 157.8 14.0 8.9 45.4 68.4 15.9 10.2 16.7 30.9 5.4 21.1 6.2 62.2 174.3 3.1 6.3 0.0 116.6 202.9 33.9 19.7 42.2 4.6 45.0 8.6 48.7 9.0 1.8 19.7 71.7 78.9 2.4 8.6 48.2 27.6 91.9 5.9 25.4 12.5 84.5 PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600183-60666280 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022277, HPA061848" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA022277: AB_1858839, HPA061848: " "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "prognostic favorable (3.52e-4)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (5.50e-2)" "unprognostic (1.70e-2)" "unprognostic (6.07e-2)" "unprognostic (2.52e-3)" "unprognostic (3.46e-2)" "unprognostic (1.95e-3)" "unprognostic (7.33e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (1.98e-1)" 4.4 2.4 2.7 2.2 5.2 5.9 3.9 14.8 4.6 4.5 5.0 3.1 2.9 4.3 2.9 3.5 3.7 3.1 2.9 3.3 3.4 2.8 2.8 3.6 2.7 4.0 3.5 6.3 3.3 2.3 2.4 5.9 4.7 3.1 3.5 6.4 3.1 2.2 4.0 2.9 2.7 3.0 3.4 3.8 2.7 5.5 3.7 4.4 2.9 3.1 2.3 2.8 4.0 9.1 3.8 6.9 7.5 6.4 5.0 3.1 10.7 5.8 3.6 3.4 4.9 7.1 2.0 9.9 4.5 3.7 1.3 3.4 4.9 2.2 4.6 1.9 11.1 7.4 6.7 8.1 4.2 2.9 5.3 2.7 3.6 5.1 3.0 2.8 7.9 4.1 5.4 4.0 3.7 34.4 8.1 4.4 3.5 3.4 5.2 9.5 9.6 6.6 3.1 4.2 10.5 7.4 7.1 2.4 1.6 8.0 2.8 3.9 5.7 4.7 12.5 3.5 3.3 6.7 7.7 7.3 1.7 2.9 3.8 9.9 16.1 18.0 7.6 12.5 6.8 8.9 6.3 7.0 16.0 6.2 6.8 7.0 24.7 8.6 8.1 7.0 10.6 9.8 2.7 5.2 14.8 4.6 3.3 3.4 4.0 3.5 4.7 3.4 3.7 9.1 40.9 32.1 7.7 15.0 23.1 21.0 6.2 3.3 52.3 13.1 14.2 9.8 6.3 8.6 4.6 5.5 4.2 17.6 19.4 15.0 3.9 6.6 68.9 14.0 15.5 25.2 14.4 14.1 19.6 6.6 6.4 14.7 10.2 15.6 1.3 7.2 23.6 4.2 8.8 3.3 20.8 11.4 6.1 21.4 19.2 12.8 13.7 16.1 3.6 28.1 12.3 7.0 6.2 20.6 38.6 5.4 10.2 7.5 24.5 7.8 8.7 5.1 3.6 10.4 0.0 12.1 14.0 43.8 15.0 34.4 18.0 38.6 18.1 6.0 11.5 7.7 PPP1R15A GADD34 ENSG00000087074 "Protein phosphatase 1 regulatory subunit 15A" O75807 19 48872421-48876058 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 575.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 340.1" "Group enriched" "Detected in all" 5 "dendritic cells: 114.6;granulocytes: 340.1" "Cell line enhanced" "Detected in all" "HHSteC: 282.8;hTERT-HME1: 493.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018395, HPA020240" Approved Uncertain Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles "CAB018395: AB_2237473, HPA020240: AB_1849404" "unprognostic (2.43e-3)" "unprognostic (3.21e-1)" "unprognostic (7.75e-2)" "unprognostic (1.17e-3)" "unprognostic (2.22e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (5.46e-2)" "unprognostic (2.66e-2)" "unprognostic (7.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.22e-1)" "unprognostic (6.43e-3)" "unprognostic (1.49e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" 199.1 84.7 33.3 49.5 37.4 575.6 97.7 45.9 54.1 99.5 66.9 78.9 36.0 70.1 11.3 98.3 147.4 82.0 185.6 34.8 36.2 95.0 85.1 226.7 33.1 44.8 32.7 101.2 33.4 23.1 65.0 74.8 42.9 60.5 45.5 10.9 41.6 38.6 88.5 191.5 58.8 101.8 29.4 69.0 90.7 23.3 38.7 52.0 69.4 60.6 20.2 110.6 108.4 46.9 55.8 23.7 24.9 20.5 71.2 40.4 39.3 95.1 148.0 106.5 95.9 36.5 27.6 19.1 25.0 69.0 145.5 39.4 9.3 49.7 79.8 10.7 14.4 86.4 14.4 18.1 282.8 20.2 119.2 55.1 135.5 147.0 493.7 48.0 56.3 21.5 118.2 155.6 69.5 6.1 11.1 27.9 6.2 100.3 42.3 12.6 23.1 6.5 22.3 63.8 14.2 24.3 49.2 33.2 230.2 26.0 11.9 36.1 60.6 126.3 31.8 89.3 58.5 82.8 72.1 17.9 46.2 13.7 154.8 161.8 49.4 91.3 22.5 31.1 19.6 36.7 22.2 18.7 35.9 29.7 12.3 11.0 340.1 13.8 37.6 114.6 31.5 36.9 33.3 37.4 45.9 54.1 34.8 36.2 44.8 32.7 42.9 29.4 38.7 46.9 499.1 288.4 225.1 2.3 387.2 482.2 989.5 232.0 730.1 25.0 294.3 220.7 173.3 127.2 204.3 12.9 35.5 104.8 290.3 435.6 3.9 224.0 4.6 619.6 427.4 370.4 170.9 213.5 4.1 94.5 219.0 466.3 430.7 1063.2 708.1 53.3 150.0 14.4 195.0 35.3 4.1 354.1 140.4 146.7 904.4 5.1 58.7 615.3 396.6 9.4 105.1 50.5 20.6 1.0 2.0 233.4 421.8 23.0 477.1 731.5 348.7 9.0 246.2 27.7 85.5 483.5 612.1 7.0 9.5 573.1 431.0 288.4 427.9 102.8 321.8 733.9 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PPP6C PP6 ENSG00000119414 "Protein phosphatase 6 catalytic subunit" O00743 9 125146573-125189939 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050940 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "HPA050940: AB_2681283" "unprognostic (6.45e-2)" "unprognostic (4.01e-3)" "unprognostic (7.12e-2)" "unprognostic (5.36e-2)" "unprognostic (2.78e-2)" "unprognostic (2.92e-2)" "unprognostic (2.57e-3)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (2.44e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.50e-6)" "unprognostic (1.54e-2)" "unprognostic (3.51e-1)" "unprognostic (1.12e-2)" "unprognostic (1.12e-1)" 32.8 25.2 20.9 24.4 22.6 42.2 29.9 22.1 27.0 22.8 18.1 28.4 20.4 19.7 23.7 25.0 18.5 18.6 21.6 21.7 22.0 32.6 25.1 24.0 30.8 21.1 20.4 19.6 27.7 32.6 14.7 19.5 21.6 20.2 30.9 17.5 26.1 19.7 69.9 23.5 22.5 21.8 21.8 27.6 20.9 28.1 20.7 38.9 31.5 53.5 36.2 22.9 18.7 26.9 32.6 23.4 41.6 39.3 43.6 36.2 41.8 33.7 36.5 48.7 40.4 37.6 33.5 46.5 25.5 45.6 41.3 64.7 56.8 36.7 56.2 42.0 27.3 38.3 33.5 33.6 35.7 67.6 50.8 30.0 49.2 40.1 38.1 37.5 46.2 52.6 45.7 52.2 53.3 48.6 64.0 42.5 38.8 90.4 42.8 51.5 62.7 62.2 42.1 32.3 42.8 42.3 60.3 47.8 41.0 35.0 74.0 42.0 45.3 29.7 28.4 58.4 45.5 57.5 112.4 62.3 40.1 43.5 49.4 61.7 21.8 35.9 22.4 28.6 27.2 26.8 28.2 25.3 24.0 20.2 27.6 26.5 50.9 23.7 33.6 17.2 38.9 25.8 20.9 22.6 22.1 27.0 21.7 22.0 21.1 20.4 21.6 21.8 20.7 26.9 39.8 41.7 37.8 20.5 62.6 77.4 55.5 64.0 60.3 14.0 42.5 28.3 37.9 31.5 43.1 27.6 8.4 45.7 43.7 47.5 56.7 46.3 130.5 22.7 21.5 44.8 47.9 60.2 35.3 55.2 57.5 37.2 34.1 24.7 45.0 20.4 48.5 41.7 52.3 15.2 30.0 43.0 67.1 61.2 60.9 83.3 29.8 51.8 44.4 32.8 60.0 29.2 40.2 22.6 35.8 48.2 37.4 36.1 82.7 47.2 43.7 79.1 34.3 12.5 52.6 28.7 46.1 124.8 48.3 76.8 87.5 87.2 57.1 23.2 43.9 59.8 PPY PNP ENSG00000108849 "Pancreatic polypeptide" P01298 17 43940804-43942476 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "pancreas: 174.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 40.5;Langerhans cells: 10.0;Pancreatic endocrine cells: 33.3" "Cancer enriched" "Detected in some" 132 "pancreatic cancer: 630.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 1.2" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.2" "Cell line enhanced" "Detected in some" "BEWO: 3.7;EFO-21: 3.2;U-2 OS: 3.9" "CAB016735, HPA032122" Enhanced "Secreted to blood" NA NA 70300 44000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB016735: , HPA032122: AB_2674164" "unprognostic (5.12e-3)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.65e-2)" "unprognostic (7.56e-3)" "unprognostic (8.13e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.42e-1)" 0.1 0.3 0.0 0.2 0.0 2.1 0.0 0.0 0.1 0.0 0.0 2.5 1.1 0.3 4.2 0.0 0.1 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.0 174.4 6.9 0.0 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.0 6.7 0.6 0.0 0.0 0.1 0.9 0.3 0.0 0.5 1.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.7 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.5 0.0 3.9 0.4 0.5 0.0 0.3 0.9 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.1 0.0 0.0 40.5 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 10.0 2.8 0.0 0.6 1.8 0.0 0.2 0.0 0.0 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.5 0.0 0.0 0.3 0.0 PRCC RCCP1 ENSG00000143294 "Proline rich mitotic checkpoint control factor" Q92733 1 156750610-156800815 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017151, HPA019463, HPA019481" Supported Enhanced "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" "CAB017151: , HPA019463: AB_1855672, HPA019481: AB_1855673" "unprognostic (6.12e-2)" "unprognostic (2.68e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (5.55e-4)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (3.03e-1)" "unprognostic (9.16e-2)" "unprognostic (3.27e-3)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "prognostic unfavorable (8.99e-15)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.02e-2)" 31.9 31.8 43.4 29.7 45.2 41.9 31.4 44.5 50.4 32.4 42.3 36.6 27.0 34.5 23.1 39.7 29.7 23.0 37.6 45.7 42.0 36.7 34.2 29.6 36.3 43.3 42.8 30.9 29.0 34.7 28.1 29.0 43.7 33.5 22.5 26.6 30.4 24.1 63.4 43.2 30.9 27.3 41.3 37.4 31.8 27.0 43.3 37.5 31.0 34.4 30.7 32.6 32.2 46.9 79.1 67.3 51.6 59.5 42.5 33.8 89.8 53.8 52.8 59.3 50.8 106.2 65.0 80.6 90.4 43.1 34.1 80.3 74.7 57.0 45.3 101.6 97.4 59.1 47.4 68.4 52.5 81.9 66.6 48.1 64.7 51.5 46.6 45.7 55.2 52.5 99.7 72.1 41.8 140.2 94.1 94.6 124.9 108.9 82.0 81.6 45.7 108.7 62.5 74.0 91.6 163.4 57.0 140.6 92.4 84.4 102.7 129.8 51.1 59.3 61.9 66.0 89.6 184.6 298.5 124.1 58.7 52.2 56.1 46.9 28.6 57.4 27.5 29.9 26.5 24.0 24.7 30.0 32.5 27.6 24.0 25.2 27.7 30.2 37.1 38.9 27.1 26.0 43.4 45.2 44.5 50.4 45.7 42.0 43.3 42.8 43.7 41.3 43.3 46.9 22.2 9.6 16.4 12.7 32.0 52.4 38.2 52.1 46.1 19.8 31.1 24.4 13.0 18.6 29.4 20.2 22.9 63.1 36.0 27.2 21.5 39.4 13.5 21.4 21.9 30.2 34.3 16.6 15.9 32.2 63.4 28.7 24.5 23.2 17.1 28.9 25.4 16.0 44.0 28.6 14.4 26.9 40.7 22.6 27.4 10.4 30.4 28.4 21.4 9.4 44.9 16.9 30.9 18.1 25.4 35.5 34.2 28.6 48.8 43.8 29.8 29.9 21.5 19.8 32.9 32.2 29.2 43.3 46.2 39.6 51.3 101.1 30.3 32.4 29.4 39.2 PRDM1 "BLIMP1, PRDI-BF1" ENSG00000057657 "PR/SET domain 1" O75626 6 105993463-106109939 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Innate immunity, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 55.2" "Cell type enhanced" "Detected in many" "dendritic cells: 199.8;Langerhans cells: 199.2;Plasma cells: 786.9;T-cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;gdT-cell: 22.1;MAIT T-cell: 34.0;memory CD4 T-cell: 20.5;memory CD8 T-cell: 20.2;naive CD8 T-cell: 11.3;neutrophil: 12.5;T-reg: 29.4" "Group enriched" "Detected in many" 5 "granulocytes: 12.5;T-cells: 34.0" "Cell line enhanced" "Detected in many" "Karpas-707: 212.1;RPMI-8226: 42.4;U-266/70: 81.5;U-266/84: 57.0" "Region enriched" "Detected in single" 6 "olfactory bulb: 3.6" "Low region specificity" "Detected in many" "HPA030033, HPA075427" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoli Nucleoplasm "HPA030033: AB_10601050, HPA075427: " "unprognostic (9.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (4.03e-1)" "unprognostic (3.77e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-2)" "unprognostic (7.56e-2)" "prognostic unfavorable (9.81e-5)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (2.45e-3)" "unprognostic (7.90e-2)" 6.6 2.1 1.6 20.0 1.6 20.3 6.8 5.5 1.8 15.7 3.1 15.2 9.2 17.2 1.3 55.2 5.5 12.7 1.7 1.5 2.8 2.5 4.5 10.1 15.9 3.2 1.8 4.9 1.9 2.5 1.4 5.1 2.7 3.4 17.2 1.3 9.3 2.4 4.3 9.1 12.6 5.5 2.4 13.6 15.2 1.2 2.9 4.2 9.0 2.2 27.8 19.6 20.2 3.4 1.4 0.5 1.1 0.0 1.6 2.1 0.2 7.2 23.3 2.3 3.7 1.4 9.2 2.0 0.4 13.8 0.3 0.5 0.0 3.6 2.5 21.7 0.1 0.4 4.9 0.0 3.6 0.8 1.6 2.3 11.6 3.3 9.7 0.7 2.9 1.0 1.4 212.1 0.4 0.0 0.1 0.5 0.8 1.4 0.0 0.5 0.0 42.4 2.1 0.3 0.0 0.3 1.0 0.9 0.0 1.6 1.0 2.4 1.5 3.1 1.8 2.1 7.2 81.5 57.0 4.9 5.1 1.3 2.1 2.4 0.8 11.1 22.1 1.2 34.0 2.5 20.5 20.2 0.5 1.0 1.8 11.3 12.5 4.7 0.3 0.4 29.4 2.6 1.6 1.6 5.5 1.8 1.5 2.8 3.2 1.8 2.7 2.4 2.9 3.4 93.1 0.0 5.1 0.3 42.1 19.5 8.6 15.0 3.4 0.6 2.8 3.4 1.5 0.0 19.1 3.7 52.1 0.7 199.8 129.8 0.0 0.3 0.9 15.9 101.0 41.1 1.8 6.1 1.8 0.2 0.7 18.5 19.4 62.6 3.8 9.9 6.4 2.5 19.8 0.0 19.2 15.0 10.2 38.0 199.2 0.3 0.0 64.5 37.4 23.4 30.4 0.5 89.6 0.5 0.1 7.8 103.7 1.2 786.9 4.0 3.2 0.3 13.0 1.1 0.0 5.3 30.1 0.5 2.3 43.9 41.5 0.7 184.3 1.6 8.7 91.9 PRDM13 PFM10 ENSG00000112238 "PR/SET domain 13" Q9H4Q3 6 99606774-99615578 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bipolar cells: 4.8;Horizontal cells: 1.7;Spermatogonia: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.8;HMC-1: 1.1;JURKAT: 2.7;RPMI-8226: 2.0;SCLC-21H: 2.3;U-266/70: 2.7;U-266/84: 1.4;WM-115: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA070592 Uncertain NA NA "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA070592: AB_2686283" "unprognostic (4.09e-1)" "unprognostic (1.68e-2)" "unprognostic (4.30e-1)" "unprognostic (3.65e-1)" "unprognostic (1.55e-1)" "unprognostic (3.16e-2)" "unprognostic (1.24e-2)" "unprognostic (2.93e-1)" "unprognostic (1.86e-2)" "unprognostic (7.54e-2)" "unprognostic (1.29e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 2.3 0.0 1.1 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.7 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.6 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRDM16 "KIAA1675, KMT8F, MEL1, MGC166915, PFM13" ENSG00000142611 "PR/SET domain 16" Q9HAZ2 1 3069168-3438621 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 16.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 173.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "NK-cell: 2.4" "Lineage enriched" "Detected in single" 16 "NK-cells: 2.4" "Cell line enhanced" "Detected in some" "HEK 293: 1.8;HHSteC: 2.0;hTERT-RPE1: 6.7;MCF7: 1.6;OE19: 3.5" "Region enriched" "Detected in many" 5 "basal ganglia: 15.7" "Low region specificity" "Detected in many" "HPA050343, HPA060467" Supported Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA050343: AB_2681099, HPA060467: AB_2684287" "unprognostic (2.44e-1)" "unprognostic (1.44e-1)" "unprognostic (5.31e-4)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "unprognostic (3.95e-2)" "unprognostic (9.15e-3)" "unprognostic (5.68e-4)" "unprognostic (2.58e-1)" "unprognostic (2.07e-2)" "unprognostic (5.21e-2)" "unprognostic (1.71e-1)" "unprognostic (7.80e-6)" "unprognostic (2.14e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (4.06e-2)" 1.6 0.2 3.7 0.5 4.8 0.0 1.1 0.1 4.1 1.3 16.2 1.1 7.4 1.0 2.1 0.3 1.4 1.1 5.4 2.8 0.6 6.8 0.2 2.5 0.5 0.5 1.7 1.5 5.8 0.9 0.6 0.1 0.9 0.7 0.2 0.0 0.4 2.2 0.4 0.5 2.6 0.2 0.0 2.1 9.3 0.7 4.1 0.1 8.0 0.6 0.3 0.9 1.1 1.5 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.3 0.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.1 1.8 0.0 0.0 0.3 2.0 0.0 0.7 0.0 0.0 0.0 0.0 6.7 0.0 0.1 0.0 0.0 0.0 1.6 0.1 0.0 0.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 3.7 4.8 0.1 4.1 2.8 0.6 0.5 1.7 0.9 0.0 4.1 1.5 4.5 35.3 10.5 173.7 0.1 0.6 0.3 2.1 0.6 0.1 0.2 0.3 5.2 22.8 6.3 7.3 0.0 0.0 0.1 0.2 5.9 10.0 0.3 0.2 0.0 2.1 5.4 0.8 1.2 4.9 4.2 0.6 30.5 0.4 0.0 0.3 0.0 0.0 0.0 1.7 1.0 0.9 0.0 0.0 0.4 0.2 1.5 0.1 0.0 14.0 0.0 1.4 0.0 6.6 1.8 7.1 0.8 1.9 0.1 0.8 0.5 0.2 1.9 0.3 0.0 3.3 9.0 0.3 1.8 0.2 0.0 0.0 0.4 0.0 1.5 0.2 PRDX2 "MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA" ENSG00000167815 "Peroxiredoxin 2" P32119 19 12796820-12801800 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1316.7;Erythroid cells: 3153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008713 Approved NA NA 800000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" "CAB008713: AB_1620974" "unprognostic (1.12e-1)" "unprognostic (1.98e-3)" "unprognostic (8.58e-2)" "unprognostic (4.40e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (2.44e-1)" "unprognostic (2.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.26e-2)" "unprognostic (9.18e-2)" "prognostic favorable (5.66e-11)" "unprognostic (7.01e-3)" "unprognostic (2.15e-1)" "unprognostic (3.51e-2)" "unprognostic (1.41e-1)" 199.0 622.0 350.8 88.3 366.6 686.7 159.7 408.2 461.5 167.8 365.6 208.1 251.7 178.8 144.5 271.8 153.5 133.9 704.0 369.6 400.0 287.7 310.2 109.1 118.3 407.5 380.4 218.2 201.7 454.5 314.6 87.8 408.2 175.3 141.5 207.1 200.1 124.4 722.9 260.7 201.1 127.0 357.0 118.1 226.6 32.8 399.1 181.3 156.3 847.9 129.2 163.6 171.6 355.5 420.4 1.1 553.9 721.3 79.5 54.2 408.4 189.0 188.0 253.9 143.4 438.1 102.8 122.7 430.9 185.0 30.2 389.5 354.7 309.7 72.9 528.5 561.4 222.6 537.4 665.1 212.4 0.7 1.4 233.6 140.5 191.1 93.0 327.6 238.8 255.3 485.7 187.0 98.7 763.3 500.1 190.2 409.1 289.6 789.4 485.8 0.7 593.0 343.1 450.0 683.8 538.5 449.5 454.9 153.7 100.7 408.0 318.0 105.7 188.2 156.9 526.7 417.7 226.3 242.1 573.5 178.9 75.5 43.8 35.4 170.0 85.6 436.1 129.4 460.6 375.2 589.8 446.2 211.6 288.5 594.7 460.9 22.4 213.2 148.0 124.5 697.4 686.6 350.8 366.6 408.2 461.5 369.6 400.0 407.5 380.4 408.2 357.0 399.1 355.5 192.2 22.4 36.7 39.5 117.5 221.3 255.6 877.7 187.2 317.9 271.2 322.2 37.1 265.9 347.7 279.6 100.1 692.8 83.5 367.4 1316.7 329.5 3.1 138.6 218.5 130.3 333.7 3153.4 31.8 167.2 558.8 204.3 214.6 197.7 47.0 466.0 137.8 489.7 234.0 215.4 50.8 360.7 754.8 63.8 128.8 13.0 293.9 58.7 281.1 23.4 61.4 531.2 56.7 41.7 29.1 179.6 250.6 321.2 263.4 169.3 765.6 1097.9 152.7 373.2 157.8 142.4 273.2 4.8 7.7 368.5 229.4 508.4 144.4 816.6 475.7 243.1 PRDX4 AOE37-2 ENSG00000123131 "Peroxiredoxin 4" Q13162 X 23664262-23686397 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 1212.0" "Cell type enhanced" "Detected in all" "Late spermatids: 1007.4;Plasma cells: 810.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008659, CAB027389, CAB047362, HPA067039" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 4400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Cytosol "CAB008659: AB_1620984, CAB027389: , CAB047362: , HPA067039: " "unprognostic (3.82e-2)" "unprognostic (6.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.06e-3)" "unprognostic (1.64e-1)" "unprognostic (1.65e-2)" "unprognostic (1.29e-3)" "unprognostic (1.08e-1)" "unprognostic (8.32e-2)" "unprognostic (3.75e-2)" "unprognostic (2.97e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (7.44e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-1)" "unprognostic (4.10e-2)" 85.7 84.6 25.2 53.9 27.4 34.3 74.9 28.7 36.6 82.3 40.2 72.7 64.0 68.1 19.5 62.5 66.1 64.7 108.6 24.7 28.7 41.8 277.2 47.1 58.7 30.6 26.8 81.2 1212.0 69.2 93.8 96.2 29.6 59.9 78.8 30.2 124.9 63.2 43.7 47.8 51.3 62.9 29.7 71.9 93.5 121.4 27.5 26.5 49.5 25.4 67.1 68.9 55.7 36.8 176.4 238.2 94.5 191.1 523.9 266.6 138.0 229.6 249.2 204.9 297.5 251.4 214.3 150.0 106.1 299.0 233.6 206.5 279.8 142.6 193.8 92.5 551.5 105.8 187.8 322.1 215.9 138.4 96.9 283.6 182.6 197.7 193.5 213.8 262.0 48.4 209.7 535.4 192.8 262.3 70.3 214.5 339.8 329.5 344.9 97.2 244.3 861.2 181.0 60.5 143.8 121.7 212.6 248.6 174.9 504.1 263.1 174.4 172.7 145.1 95.1 378.4 176.1 173.8 228.6 161.5 259.9 177.0 211.9 5.9 65.6 6.9 53.8 107.8 67.4 89.9 68.1 57.1 101.6 56.0 48.4 49.7 4.8 83.8 137.8 71.3 74.6 69.8 25.2 27.4 28.7 36.6 24.7 28.7 30.6 26.8 29.6 29.7 27.5 36.8 143.8 57.7 68.2 5.5 132.8 59.8 88.6 277.2 62.0 16.7 98.8 119.0 50.7 107.2 124.0 49.7 8.4 328.7 17.9 34.0 9.8 270.4 402.0 66.5 117.4 96.2 58.7 60.6 2.4 358.8 531.6 162.1 65.2 117.6 43.1 206.7 92.1 539.5 173.4 11.8 3.3 151.6 187.2 54.2 55.1 1007.4 252.5 47.1 199.3 1.9 75.2 55.0 27.8 8.5 7.3 241.4 44.1 144.0 810.1 174.6 61.2 54.2 89.9 21.7 144.7 79.2 185.3 258.2 251.7 83.3 52.1 258.6 42.0 311.8 115.7 73.1 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in some" "dendritic cells: 542.1;NK-cells: 1231.7;T-cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8" "Group enriched" "Detected in all" 50 "NK-cells: 656.8;T-cells: 900.4" "Cell line enriched" "Detected in some" 11 "HDLM-2: 240.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" NA NA 2100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" 5.0 2.0 0.7 7.6 0.7 28.6 2.7 0.7 1.3 1.3 1.3 2.2 2.3 3.5 1.1 1.9 1.9 4.2 2.2 0.6 0.6 1.7 6.3 16.5 20.3 1.4 0.7 1.0 1.0 0.5 0.9 2.7 1.0 1.5 1.4 0.0 2.3 1.2 2.6 0.9 5.2 2.0 1.3 49.4 4.7 0.6 1.0 5.8 2.6 1.5 4.9 3.8 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 240.1 0.0 1.4 0.0 7.4 0.0 0.3 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 5.2 1.9 0.9 900.4 1.7 628.8 4.0 125.8 499.1 2.0 3.5 52.1 313.0 15.4 656.8 2.6 2.9 108.8 587.5 0.7 0.7 0.7 1.3 0.6 0.6 1.4 0.7 1.0 1.3 1.0 1.0 3.1 3.2 13.6 0.0 4.4 0.4 0.1 0.0 0.6 0.0 0.5 0.5 0.8 1.5 2.5 0.0 0.0 0.2 542.1 0.1 0.0 0.3 0.0 0.2 0.3 1.9 0.0 19.0 0.0 0.0 0.1 2.1 7.7 0.4 8.8 0.0 10.8 2.7 0.1 0.0 0.0 0.0 0.0 7.8 2.3 0.0 0.0 5.7 0.0 1.9 7.4 0.0 1231.7 0.0 0.1 0.0 0.0 0.0 88.5 0.1 0.1 1.6 1.5 0.0 0.0 1.1 0.8 0.0 0.0 0.5 0.9 0.7 265.4 0.0 0.1 0.0 PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 310.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 116.8;Theca cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010361, HPA071185" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "Cytokinetic bridge" "CAB010361: AB_2268772, HPA071185: AB_2686356" "unprognostic (1.08e-1)" "prognostic favorable (6.28e-6)" "unprognostic (2.09e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (1.38e-2)" "unprognostic (2.95e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (7.01e-2)" "unprognostic (3.41e-1)" "prognostic favorable (6.47e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.66e-2)" "unprognostic (6.14e-3)" 62.7 126.5 46.6 27.6 47.6 18.9 53.9 39.9 64.2 53.2 29.5 59.0 20.9 56.9 28.5 41.8 53.7 14.2 204.8 49.2 53.3 35.4 78.4 46.1 15.9 56.8 54.5 94.1 34.0 21.6 71.2 17.3 55.3 41.2 13.0 25.2 42.3 20.8 310.9 42.3 36.3 21.8 40.7 71.6 40.2 57.2 50.3 18.2 39.6 122.1 13.4 50.6 44.2 46.6 37.5 16.3 40.3 74.4 36.2 30.8 9.9 30.5 23.6 32.7 27.5 21.6 15.0 13.8 26.2 49.2 22.9 25.4 26.7 26.6 32.3 23.1 17.7 27.7 20.6 24.4 36.8 21.9 33.5 33.8 18.1 30.0 11.1 26.6 29.7 19.0 29.1 47.3 36.7 48.1 46.3 31.9 21.5 38.7 45.0 38.0 47.8 36.7 41.7 13.5 36.5 24.2 34.2 31.3 23.8 18.1 37.2 26.5 37.7 71.7 20.3 100.7 39.6 31.9 24.9 23.6 49.6 28.0 32.7 0.1 1.5 0.2 0.8 2.7 0.3 0.8 0.3 0.5 1.1 0.5 0.5 0.7 3.2 0.4 2.5 0.6 0.3 0.6 46.6 47.6 39.9 64.2 49.2 53.3 56.8 54.5 55.3 40.7 50.3 46.6 39.5 6.4 3.4 9.4 7.0 8.8 6.8 6.4 2.2 42.2 19.2 19.0 116.8 22.8 4.7 14.7 27.1 6.9 9.0 24.6 7.9 12.4 32.4 11.7 22.9 26.7 17.5 2.5 16.9 19.1 5.7 22.6 8.6 12.9 0.0 15.9 26.4 39.7 34.5 3.3 21.6 11.8 2.0 49.4 50.8 15.7 49.0 37.1 14.2 9.4 37.8 26.1 9.2 10.1 10.7 15.6 11.6 51.9 3.3 6.4 20.7 11.8 7.0 23.9 19.7 23.3 23.5 26.4 6.9 10.1 11.2 8.1 10.0 100.6 14.4 6.6 PRKAR1A "CNC1, PRKAR1, TSE1" ENSG00000108946 "Protein kinase cAMP-dependent type I regulatory subunit alpha" P10644 17 68511780-68551319 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 606.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019378, HPA049979" Approved Approved Cytosol NA NA 1800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "CAB019378: , HPA049979: AB_2680980" "unprognostic (8.69e-2)" "unprognostic (6.97e-2)" "unprognostic (5.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.68e-1)" "unprognostic (4.39e-2)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (5.55e-2)" "unprognostic (8.56e-3)" "unprognostic (6.26e-2)" "unprognostic (6.92e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" 125.9 158.2 72.0 124.1 83.2 57.1 118.4 76.7 119.1 151.2 97.3 70.0 51.7 145.5 122.3 98.5 141.3 125.2 430.0 89.0 102.1 164.3 150.8 163.7 111.4 85.6 91.8 202.8 63.1 300.2 88.0 164.3 105.0 114.5 79.1 132.2 169.7 137.6 250.6 63.8 58.7 132.1 71.7 121.7 86.9 130.8 91.8 109.4 173.6 147.4 103.6 136.4 67.6 93.5 95.5 180.0 225.9 136.1 294.6 331.7 33.9 125.7 257.9 192.2 168.6 70.5 125.5 96.3 84.3 276.7 196.8 77.2 168.8 204.2 273.8 65.8 60.4 149.1 154.0 233.0 213.0 115.8 160.2 239.1 207.4 222.3 185.9 215.0 324.6 80.8 68.5 147.2 236.4 181.0 128.2 60.9 83.9 97.7 121.4 88.1 373.6 106.7 292.4 204.3 81.8 110.3 115.4 207.6 496.8 208.5 162.8 161.1 232.2 269.4 127.6 123.3 119.0 121.6 93.5 142.4 163.0 107.8 171.8 149.6 108.3 189.4 48.6 101.0 48.8 42.8 35.9 43.6 105.9 32.3 32.1 35.9 208.2 76.1 120.9 34.7 50.9 113.5 72.0 83.2 76.7 119.1 89.0 102.1 85.6 91.8 105.0 71.7 91.8 93.5 134.1 147.4 263.4 38.5 126.0 142.8 100.1 136.8 116.7 99.6 106.8 65.4 606.2 81.5 156.4 252.0 66.7 77.4 127.4 58.1 178.1 80.7 407.9 142.9 116.4 131.8 136.9 52.5 76.1 52.0 86.8 163.2 78.5 110.3 185.0 78.2 158.1 120.7 146.1 139.7 78.4 53.3 136.3 176.2 171.1 93.7 133.6 151.1 192.1 46.9 142.3 125.1 78.2 57.3 76.3 74.6 51.5 190.7 95.6 85.3 27.1 210.1 307.7 59.9 85.5 123.2 210.9 219.8 54.2 122.4 131.7 82.5 117.3 184.0 43.9 112.8 PRKCA "PKCA, PKCα" ENSG00000154229 "Protein kinase C alpha" P17252 17 66302613-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.8" "Cell type enhanced" "Detected in many" "Astrocytes: 564.8;Excitatory neurons: 247.6;Inhibitory neurons: 400.0;Microglial cells: 281.1;Oligodendrocyte precursor cells: 849.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 157.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" NA NA 190000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 3.1 21.1 37.0 6.9 35.0 1.8 2.3 20.8 51.4 7.5 11.8 18.5 11.9 11.7 4.8 3.2 4.6 7.5 4.4 76.8 32.8 12.8 7.3 4.5 4.9 37.3 36.1 15.7 5.1 0.9 6.3 5.0 25.3 13.0 8.6 30.1 2.3 16.9 5.8 3.0 10.6 10.7 30.1 6.5 8.4 2.6 36.9 3.1 3.2 4.3 4.6 8.9 5.6 27.3 7.3 38.0 7.7 7.8 18.2 46.0 1.0 40.8 26.4 28.8 24.3 4.5 4.6 9.6 10.9 65.9 48.1 0.9 3.9 4.8 61.9 16.4 9.3 0.0 22.2 20.2 24.9 12.2 62.8 20.2 1.8 36.0 30.5 41.8 25.0 45.6 25.8 0.2 44.8 2.3 24.9 7.4 3.1 18.9 20.2 4.5 56.5 0.2 10.2 6.4 4.6 25.6 13.5 7.7 0.4 8.0 0.8 17.0 75.1 49.6 28.6 31.4 25.8 0.1 0.0 1.2 157.6 0.1 25.1 0.0 0.2 0.0 0.1 0.2 0.5 0.0 0.8 0.4 0.3 0.0 1.2 0.7 0.0 0.0 1.1 0.4 0.1 0.3 37.0 35.0 20.8 51.4 76.8 32.8 37.3 36.1 25.3 30.1 36.9 27.3 10.0 0.0 8.4 564.8 5.7 10.6 15.0 10.3 13.6 198.3 7.9 11.2 9.8 45.8 7.2 40.5 2.1 4.1 24.6 27.1 7.9 16.1 3.2 5.5 40.1 5.6 8.4 5.7 247.6 6.8 3.4 17.5 23.9 6.3 20.3 39.9 27.8 14.7 25.4 10.1 400.0 38.4 2.0 11.9 7.6 3.0 53.4 20.9 10.6 281.1 6.8 34.3 12.3 849.0 198.3 8.8 21.0 48.5 11.8 12.8 27.0 21.3 7.0 77.1 26.3 6.5 41.4 1.3 3.9 6.1 10.4 15.2 36.9 47.1 26.4 17.2 PRKCB "PKCβ, PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835983-24220611 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.0;lymphoid tissue: 47.2" "Cell type enhanced" "Detected in many" "B-cells: 185.1;Bipolar cells: 208.6;Excitatory neurons: 877.7;Inhibitory neurons: 320.2;Kupffer cells: 221.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 95 "amygdala: 28.9;basal ganglia: 53.9;cerebral cortex: 84.0;hippocampal formation: 35.3;white matter: 36.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 161.8;HMC-1: 154.8;K-562: 234.9;THP-1: 72.7;U-937: 64.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol NA NA 380000 "Cluster 6: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: AB_2680357, HPA054203: AB_2682416" "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.4 1.6 28.9 30.8 53.9 32.1 1.5 0.5 84.0 4.2 0.0 9.7 5.9 3.8 0.6 3.5 3.8 4.4 1.1 35.3 0.0 2.8 4.2 7.8 47.1 0.0 0.0 0.6 1.0 0.2 1.4 2.7 0.0 7.3 5.1 18.2 1.5 10.2 0.8 5.5 19.4 7.2 0.0 46.2 5.7 8.4 0.0 47.2 4.5 1.0 40.0 8.7 1.7 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 1.0 0.0 0.3 0.5 0.5 0.0 0.0 0.0 3.2 161.8 7.5 0.0 0.0 23.6 154.8 0.0 0.7 0.0 0.0 0.0 0.0 27.3 234.9 0.6 0.0 0.0 52.1 51.4 1.5 0.0 0.0 49.0 0.4 9.5 0.5 14.1 27.2 0.0 0.2 0.2 2.4 0.8 0.0 72.7 1.1 0.0 0.3 0.1 0.0 4.1 0.0 1.4 0.2 64.4 0.3 39.3 13.3 27.8 24.8 20.0 11.5 44.2 15.9 29.9 11.3 40.0 13.0 32.0 39.1 39.9 28.6 33.8 12.7 15.5 28.9 53.9 0.5 84.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 36.6 1.1 3.2 4.9 21.5 185.1 6.0 4.1 0.1 0.6 208.6 0.9 0.8 2.0 2.8 1.8 1.8 2.1 0.2 166.3 1.4 0.0 0.0 26.5 0.1 0.1 4.1 0.0 26.3 877.7 0.2 0.3 1.7 1.5 0.1 71.5 1.9 11.4 3.1 50.5 79.1 320.2 1.5 0.0 221.9 20.5 11.7 0.0 100.9 3.6 110.5 154.4 10.8 120.5 102.1 132.5 0.0 9.6 0.4 61.8 1.0 6.7 0.8 1.6 9.9 0.0 4.4 1.6 3.4 3.6 0.5 14.3 0.8 68.1 0.2 3.8 4.5 PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 57.0;granulocytes: 52.9;monocytes: 73.7" "Cell line enhanced" "Detected in all" "SK-BR-3: 267.7;THP-1: 194.0" "Group enriched" "Detected in all" 5 "basal ganglia: 121.4;thalamus: 334.6" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 30000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" 46.1 59.7 10.4 45.4 11.1 90.3 28.9 4.4 11.7 25.9 7.3 43.5 54.8 9.1 39.1 32.7 42.3 32.8 19.6 12.8 11.0 25.6 8.8 44.3 46.8 9.9 8.5 13.6 33.2 20.7 8.2 20.5 7.5 39.3 41.5 2.2 25.9 31.9 6.8 34.0 55.7 16.2 9.5 54.2 65.1 20.8 9.0 16.3 41.8 9.2 62.1 44.2 23.2 12.3 33.5 14.4 5.2 8.7 35.9 21.6 46.2 20.4 25.7 24.5 23.7 34.4 31.9 86.5 8.3 45.6 42.9 14.5 34.1 49.8 20.6 75.2 23.6 50.1 18.3 32.0 23.6 64.8 103.4 17.1 35.8 25.6 23.2 21.8 22.4 9.3 9.7 11.8 36.1 85.0 7.0 81.0 13.0 51.5 23.0 7.6 13.6 20.6 25.5 72.8 8.3 6.5 15.4 267.7 39.6 24.0 22.6 194.0 31.5 11.7 14.4 15.4 19.2 18.1 33.6 45.9 27.6 116.4 22.6 51.8 73.7 50.1 3.6 71.3 2.2 6.2 2.1 2.5 57.0 8.2 2.2 2.0 52.9 6.9 47.7 16.3 2.6 24.1 10.4 11.1 4.4 11.7 12.8 11.0 9.9 8.5 7.5 9.5 9.0 12.3 4.3 3.2 23.5 2.0 25.7 29.2 26.3 8.0 23.9 0.3 11.8 4.3 6.4 14.3 16.1 14.7 0.0 3.1 24.7 61.8 3.9 8.9 34.5 18.5 4.4 2.7 26.5 5.2 3.4 10.7 16.0 6.7 54.0 17.8 5.7 8.9 3.3 2.3 44.8 1.7 4.2 37.1 4.1 47.4 43.0 75.6 9.0 41.5 10.6 20.6 44.9 2.0 8.2 1.0 0.5 13.2 55.4 6.8 25.8 19.7 64.5 13.1 16.5 0.2 6.6 6.5 12.1 23.1 3.7 23.9 27.8 8.8 10.0 10.4 23.0 34.6 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 128.4;Microglial cells: 267.9;NK-cells: 229.6;T-cells: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Cell line enhanced" "Detected in many" "BEWO: 81.8;HUVEC TERT2: 108.7;MOLT-4: 75.8;RT4: 46.4;TIME: 72.0" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 26.6 7.8 21.1 21.9 30.2 24.2 21.9 12.4 15.7 20.6 9.5 8.9 9.5 14.5 10.9 30.0 13.6 19.7 19.2 13.2 13.9 14.5 10.3 35.3 55.2 19.3 21.7 5.9 8.4 14.2 15.0 32.5 19.4 15.8 8.8 3.1 28.3 11.4 14.2 23.7 16.6 18.1 18.6 38.5 9.6 7.5 29.9 65.8 21.1 18.1 38.5 25.3 21.7 15.5 18.1 6.3 0.8 4.9 2.8 0.6 81.8 0.3 1.5 0.8 0.8 1.9 10.5 0.3 12.4 0.1 1.6 12.3 0.6 13.5 1.4 2.2 7.9 0.1 2.0 0.7 1.2 0.0 2.4 2.2 13.8 0.7 9.4 1.2 108.7 35.4 0.2 0.4 6.2 32.7 75.8 0.7 1.4 12.9 8.4 6.3 3.2 0.2 0.2 46.4 3.2 5.1 2.1 16.2 10.2 14.5 15.9 1.4 72.0 2.1 14.0 2.1 0.9 1.4 0.2 0.6 3.1 1.1 3.6 0.8 3.0 2.4 116.5 1.9 91.3 2.2 88.0 137.0 9.2 1.4 106.9 105.5 5.9 117.1 1.1 3.0 79.8 84.0 21.1 30.2 12.4 15.7 13.2 13.9 19.3 21.7 19.4 18.6 29.9 15.5 59.7 6.4 11.4 2.0 6.6 18.7 16.4 8.3 15.9 0.4 15.0 9.3 9.0 10.0 15.5 0.0 0.0 27.6 128.4 0.6 3.9 6.0 32.6 10.3 2.1 70.8 11.9 18.1 1.7 6.8 21.2 5.0 7.1 20.9 1.3 15.4 68.9 2.0 6.0 0.0 3.1 2.7 2.0 14.4 6.9 6.0 1.8 15.4 16.0 267.9 8.9 7.0 229.6 4.5 1.8 5.4 4.3 6.8 26.6 14.7 4.6 1.2 9.2 0.5 0.0 4.4 5.2 0.1 2.4 18.1 26.7 48.3 130.5 1.6 1.3 26.0 PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222424-170305977 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Cytokinetic bridge" "HPA026574: AB_1855428, HPA038635: AB_2676124" "unprognostic (2.26e-1)" "unprognostic (6.75e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (3.93e-6)" "unprognostic (1.59e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.52e-1)" "unprognostic (7.10e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (5.32e-3)" "prognostic favorable (3.10e-4)" "unprognostic (1.16e-1)" "unprognostic (2.65e-1)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" 6.7 5.0 2.0 6.9 2.4 2.6 10.4 2.0 3.2 12.7 0.3 12.4 11.6 11.0 8.2 15.1 15.9 11.4 6.9 3.4 1.1 13.5 7.3 16.6 4.6 0.4 0.2 13.6 7.0 13.0 3.1 10.9 0.5 17.3 13.1 6.2 17.5 12.7 6.2 6.9 10.8 11.0 0.2 5.2 34.5 12.5 0.9 10.9 24.5 9.8 10.4 16.1 6.2 1.1 81.6 20.2 20.0 21.6 17.3 23.9 32.2 20.4 29.9 26.4 28.3 29.7 38.6 24.7 65.3 28.8 36.4 37.3 37.9 40.0 44.8 18.2 23.5 22.9 24.3 16.6 27.9 20.9 10.0 21.8 27.5 22.6 35.1 42.8 20.9 13.3 25.8 19.8 27.4 28.0 30.5 8.5 42.3 86.4 22.1 21.8 30.7 41.2 42.3 24.4 31.5 25.8 44.1 57.7 20.0 29.5 63.0 14.5 22.4 27.5 21.1 26.0 34.3 33.9 34.9 35.2 19.8 16.4 11.0 0.0 0.6 0.4 1.1 0.6 1.7 0.9 1.5 2.0 0.8 1.2 1.6 0.9 0.3 2.6 0.5 0.8 1.1 0.7 2.0 2.4 2.0 3.2 3.4 1.1 0.4 0.2 0.5 0.2 0.9 1.1 17.6 73.7 82.1 23.2 5.8 57.1 49.5 39.8 30.7 16.4 29.0 19.7 16.2 24.3 45.3 49.7 14.6 30.2 15.0 29.0 25.4 16.5 8.4 42.0 29.7 20.5 29.3 10.5 77.2 22.0 26.6 32.2 59.7 72.3 8.8 20.4 17.5 17.7 10.0 15.2 55.2 28.3 50.8 18.6 26.8 6.8 23.3 11.6 17.8 22.5 12.7 8.8 6.2 33.2 33.5 55.2 18.6 28.6 29.4 99.4 18.7 20.4 31.9 9.4 19.7 23.7 18.7 15.8 20.6 38.5 63.6 20.7 14.8 14.3 28.5 80.1 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 33.6;skeletal muscle: 124.5;tongue: 112.6" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;dendritic cells: 22.4;NK-cells: 32.0;Oligodendrocyte precursor cells: 24.6;Oligodendrocytes: 75.2;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.0;MAIT T-cell: 18.0;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.5;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.7" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.7" "Cell line enhanced" "Detected in many" "HEL: 57.8;JURKAT: 40.0;MOLT-4: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.8 0.7 5.3 5.2 8.5 5.7 0.9 6.1 6.3 1.6 12.1 1.4 1.5 2.5 8.3 2.2 3.9 1.5 0.3 5.5 8.2 10.9 1.0 5.3 12.3 6.5 8.6 1.3 3.4 0.7 0.8 0.2 6.4 1.8 1.7 1.5 1.4 1.1 124.5 0.3 3.3 0.7 5.5 5.0 2.1 1.1 7.2 33.6 14.9 112.6 9.4 2.2 0.6 9.8 0.1 5.3 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.2 0.4 3.4 0.3 0.0 0.0 0.0 0.0 3.3 6.0 0.0 0.0 3.9 57.8 0.0 0.4 0.7 2.8 0.6 0.3 3.5 0.1 0.2 0.0 0.5 40.0 12.8 0.1 0.0 0.0 43.9 8.0 5.8 0.5 0.0 8.5 1.3 0.0 11.6 2.9 0.4 2.1 0.0 0.0 0.0 3.4 0.0 5.8 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 2.4 0.1 0.3 23.0 0.4 18.0 0.1 24.5 24.5 0.2 0.0 19.1 17.9 1.6 13.3 0.0 0.0 39.7 10.5 5.3 8.5 6.1 6.3 5.5 8.2 6.5 8.6 6.4 5.5 7.2 9.8 0.2 3.2 7.0 22.9 0.8 0.0 0.3 0.3 0.6 1.6 0.3 0.3 0.4 0.0 0.7 1.8 0.0 0.0 22.4 0.0 7.9 0.3 2.1 0.5 1.2 0.2 1.8 8.0 13.7 0.8 0.1 0.7 1.5 3.0 1.3 8.2 1.1 0.0 0.5 0.0 14.7 0.5 0.0 1.3 0.5 5.6 0.0 1.7 0.0 7.5 0.8 1.2 32.0 24.6 75.2 0.1 0.1 0.0 10.2 0.2 0.0 0.3 0.9 0.4 0.0 4.2 0.4 1.0 2.2 0.5 0.0 0.0 31.7 0.3 0.4 0.1 PRKDC "DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic subunit" P78527 8 47773111-47960178 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, Ribosome biogenesis" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm NA NA 250000 "Cluster 6: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB005167: AB_2172845, HPA035174: AB_2674504" "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 17.3 16.8 8.6 14.1 10.7 19.2 16.1 9.8 11.9 18.2 10.8 16.2 7.0 20.1 8.0 24.0 18.3 7.4 16.7 10.6 9.3 14.8 14.0 14.8 17.9 10.4 10.0 19.8 18.0 14.0 16.3 10.9 9.8 13.5 11.6 23.8 16.0 9.2 26.4 19.8 17.2 12.1 10.6 18.8 16.6 18.3 9.6 27.8 13.4 15.0 17.1 18.7 17.5 14.3 123.5 103.4 98.4 93.9 59.9 63.0 41.6 51.2 49.9 70.3 68.9 68.0 39.6 117.1 43.1 63.3 52.3 68.5 131.3 70.2 109.3 26.3 81.8 230.2 92.1 83.7 25.8 88.6 46.0 45.9 22.5 111.3 115.3 27.1 73.4 79.5 156.6 48.0 78.8 57.7 125.8 72.3 108.6 85.6 31.2 60.8 77.3 41.2 35.5 104.4 49.2 62.5 158.1 50.6 51.1 60.2 72.6 60.1 86.2 91.5 78.0 73.0 104.2 41.3 56.7 162.8 51.7 97.9 75.6 11.4 8.1 4.1 8.7 6.8 11.0 13.1 10.8 9.2 6.5 16.7 11.2 10.3 7.7 12.8 13.7 15.3 8.3 2.9 8.6 10.7 9.8 11.9 10.6 9.3 10.4 10.0 9.8 10.6 9.6 14.3 73.4 38.5 36.1 56.8 67.9 38.4 48.3 59.7 77.4 103.4 63.1 64.0 82.1 22.8 44.1 42.3 125.1 61.1 81.9 17.5 17.6 41.9 29.0 66.0 166.5 59.7 25.8 147.6 85.5 36.0 60.6 73.2 55.0 72.6 45.6 105.1 32.5 41.2 35.9 104.3 77.1 31.2 38.7 45.5 20.1 15.5 56.8 54.6 19.6 61.8 63.6 73.1 57.7 82.0 76.0 34.9 16.6 69.6 69.3 57.1 13.2 23.5 50.1 111.6 52.6 91.2 69.3 100.7 106.3 85.3 40.6 33.0 71.0 143.2 55.2 36.4 PRL ENSG00000172179 Prolactin P01236 6 22287244-22302826 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Lactation Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1022 "pituitary gland: 37505.3" "Group enriched" "Detected in some" 5 "Early spermatids: 13.8;Late spermatids: 28.4;Rod photoreceptor cells: 14.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 31.0;SCLC-21H: 8.9;U-937: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB023353, HPA042416, HPA062017" Enhanced "Secreted to blood" NA NA 53900000 7200000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "CAB023353: AB_617369, HPA042416: AB_2677987, HPA062017: AB_2684660" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (5.89e-3)" "unprognostic (4.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.11e-4)" "unprognostic (4.54e-1)" "unprognostic (1.57e-1)" "unprognostic (3.79e-2)" "unprognostic (4.29e-5)" "unprognostic (2.20e-1)" 3.2 11.2 0.3 1.4 0.0 0.0 1.2 0.6 0.1 0.8 0.1 2.7 0.1 11.5 0.0 11.7 1.6 0.1 4.6 0.0 0.2 2.4 9.6 2.1 0.0 0.9 0.7 4.0 5.5 0.0 37505.3 36.6 1.1 2.3 0.0 33.7 3.6 0.0 2.4 7.7 2.5 2.2 0.0 4.0 19.3 4.0 1.0 4.0 14.2 0.0 0.0 0.4 1.6 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.1 0.4 0.0 0.2 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.2 0.9 0.7 1.1 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.0 13.8 0.1 3.5 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.3 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 2.5 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 PRPF8 "hPrp8, Prp8, PRPC8, RP13, SNRNP220" ENSG00000174231 "Pre-mRNA processing factor 8" Q6P2Q9 17 1650629-1684867 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 252.3;Rod photoreceptor cells: 293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009941, CAB015457" Supported Enhanced Nucleoplasm NA NA 120000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB009941: AB_2171185, CAB015457: AB_831685" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-2)" "unprognostic (3.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.94e-2)" "unprognostic (6.58e-2)" "unprognostic (1.56e-1)" "unprognostic (4.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (2.45e-3)" "unprognostic (2.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" 78.5 128.7 82.6 45.7 85.0 70.5 78.6 93.2 121.3 98.5 98.7 93.5 33.0 94.5 44.1 85.3 94.2 30.8 100.9 84.4 84.0 78.2 91.2 84.2 52.8 83.6 82.1 131.6 78.3 82.7 130.4 44.7 86.2 89.7 44.5 115.6 78.1 49.1 146.7 92.6 84.2 51.7 80.9 98.2 80.5 100.1 81.5 83.9 89.0 80.1 61.6 96.9 84.3 88.0 104.0 240.7 149.0 116.1 120.8 90.4 107.9 78.2 109.5 160.3 122.4 208.2 50.0 150.0 73.2 150.5 113.4 152.9 356.3 139.5 181.6 99.4 170.0 124.3 187.1 161.0 73.5 145.4 138.9 86.0 91.2 194.8 146.7 84.5 146.1 106.2 121.1 126.6 117.9 112.7 114.4 117.4 97.0 97.7 74.4 218.4 82.3 80.7 63.1 121.1 71.0 103.8 145.0 61.5 69.3 121.6 87.4 91.3 122.1 91.7 78.3 130.2 176.1 46.6 46.7 101.9 81.6 108.1 121.6 23.1 8.9 10.1 19.1 14.4 23.6 17.5 17.7 20.9 15.7 18.3 16.7 20.0 9.0 14.2 21.7 25.2 23.2 11.2 82.6 85.0 93.2 121.3 84.4 84.0 83.6 82.1 86.2 80.9 81.5 88.0 45.7 60.9 84.3 24.5 72.8 30.1 30.0 42.5 56.9 128.0 31.8 34.4 39.4 42.9 53.9 47.8 252.3 43.3 66.6 42.9 7.9 35.5 11.8 45.4 38.8 46.3 36.5 73.0 23.6 40.9 26.7 48.3 56.1 40.3 52.6 55.9 37.9 38.7 39.8 72.3 29.3 40.2 32.6 40.1 26.5 11.2 73.3 42.6 19.6 19.7 48.3 55.9 46.4 21.6 19.0 42.7 36.5 52.3 70.0 31.4 48.7 18.3 51.3 293.2 72.3 65.4 44.8 100.4 99.1 57.3 27.8 39.5 62.8 50.2 50.3 31.5 PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 351.7;Endometrial stromal cells: 158.6;Fibroblasts: 180.2;Late spermatids: 390.0;Leydig cells: 256.3;Oligodendrocyte precursor cells: 288.5;Smooth muscle cells: 206.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 367.0;ASC TERT1: 290.5;BJ: 109.7;BJ hTERT+: 213.2;HSkMC: 150.6;U-138 MG: 146.0;U-2197: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" 96.3 10.2 14.5 17.7 15.2 0.0 42.9 15.4 13.4 92.0 5.4 5.6 1.1 68.6 20.3 20.1 42.3 34.1 44.2 12.6 26.2 2.3 0.4 21.7 34.6 17.4 18.5 28.2 3.8 7.5 4.9 6.3 16.8 33.5 5.7 0.1 38.5 75.6 51.7 24.1 3.6 52.4 7.9 1.9 3.4 14.2 16.5 18.7 41.6 73.9 36.3 33.0 58.8 15.0 0.0 0.0 2.1 0.0 367.0 290.5 0.1 109.7 213.2 15.0 14.8 0.0 0.1 0.1 0.0 90.2 0.0 0.0 18.5 0.0 4.7 0.0 0.2 0.0 1.6 0.0 1.2 0.0 0.0 150.6 0.0 73.4 0.4 25.7 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.0 0.0 0.1 146.0 2.6 140.4 16.9 0.0 0.0 0.0 77.3 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 15.2 15.4 13.4 12.6 26.2 17.4 18.5 16.8 7.9 16.5 15.0 49.8 0.0 0.5 114.3 0.3 16.3 0.6 0.1 4.0 0.0 1.3 10.2 29.8 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.2 351.7 4.9 158.6 11.4 0.0 0.0 17.4 0.2 0.1 180.2 0.5 3.5 0.0 0.6 0.0 0.0 0.8 0.0 5.5 0.0 0.0 0.0 27.9 390.0 256.3 2.8 14.2 124.6 0.0 0.5 0.0 288.5 0.9 0.7 0.0 104.6 0.4 1.7 0.0 0.1 0.0 0.2 52.6 59.1 206.5 15.4 1.9 1.2 11.8 0.1 2.3 0.6 0.0 1.2 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1923 "pancreas: 341429.7" "Cell type enriched" "Detected in some" 28 "Exocrine glandular cells: 57138.3" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "OE19: 10.6;RPMI-8226: 4.5;U-2 OS: 2.8" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 100000000000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavorable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.12e-1)" 45.2 9.9 0.0 4.7 0.0 0.0 25.7 0.0 0.0 19.9 0.0 11.2 54.5 8.9 0.8 15.2 5.6 0.0 51.0 0.0 0.0 9.6 29.7 6.4 6.5 0.0 0.0 177.5 341429.7 0.1 10.3 13.9 0.0 15.2 0.0 0.0 44.2 4.2 8.9 12.1 12.7 0.0 0.0 13.4 77.1 6.9 0.0 0.0 6.4 0.0 0.0 4.7 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 100.7 0.0 0.1 0.0 3.6 0.0 0.0 0.0 57138.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 119.4 0.6 0.0 0.0 0.0 1985.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.2 0.2 PSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 3019.3" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 5332.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 22.4;HeLa: 45.7;OE19: 17.6;RT4: 61.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 38.2" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" 4.8 0.4 0.5 0.5 0.6 0.2 1.9 0.3 0.9 67.8 0.2 7.8 4.0 0.4 0.6 334.0 7.9 10.0 0.4 0.6 0.2 5.8 0.7 6.3 0.1 0.5 0.3 0.6 3.2 0.0 0.6 2.4 0.4 230.6 4.8 0.0 23.5 1.9 0.3 11.1 2.5 0.1 0.2 0.4 3019.3 1.4 0.5 0.4 0.4 0.0 15.0 629.0 167.7 0.5 10.7 0.7 0.0 0.0 2.1 6.8 10.6 4.9 1.1 2.1 1.8 0.1 22.4 0.0 0.4 0.4 8.1 2.1 0.0 0.4 1.3 0.6 0.0 0.0 45.7 0.0 0.1 0.0 1.5 6.0 7.8 4.6 0.0 0.6 0.0 0.0 0.0 0.0 1.7 5.8 1.7 0.6 1.2 17.6 1.2 0.7 0.0 0.9 1.0 61.7 0.2 0.5 5.1 15.6 3.5 0.3 0.2 0.2 1.0 1.5 1.7 2.7 0.0 1.9 0.1 0.0 2.9 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.9 0.6 0.2 0.5 0.3 0.4 0.2 0.5 0.5 0.2 3.2 1.5 1.6 7.7 0.9 26.0 120.0 0.0 0.0 3.9 2.7 1.2 71.4 894.2 1.8 0.0 2.3 0.0 1.9 7.9 3.2 0.3 1.3 0.1 1.1 275.1 0.0 0.3 1.2 5.0 3.3 5332.3 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 12.9 179.0 0.6 1.0 0.4 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 57.1 0.2 0.0 13.4 238.7 0.3 0.4 994.9 0.0 0.0 0.0 48.9 0.0 0.5 13.1 1.3 28.5 4.6 0.0 0.9 1241.5 PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Oligodendrocytes: 395.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: AB_2685853" "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favorable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" 25.1 22.6 44.3 26.5 80.7 39.6 28.2 62.4 56.0 28.1 48.9 49.5 50.2 25.3 26.9 35.2 22.9 31.7 18.0 47.4 51.6 35.5 31.9 32.1 22.4 73.0 63.8 22.0 22.9 35.1 11.6 43.1 71.5 24.3 46.3 23.4 22.9 23.4 18.4 38.2 49.0 27.1 55.7 22.6 31.0 32.5 60.8 26.2 36.9 23.3 30.7 35.0 19.2 119.1 37.1 55.9 50.6 20.0 68.9 49.9 46.7 52.5 60.1 52.6 66.7 69.9 88.9 23.7 34.1 50.5 43.0 94.9 43.2 40.1 57.3 54.6 26.7 27.1 35.1 34.4 63.8 27.7 50.7 50.4 71.9 44.3 54.4 48.5 43.2 26.2 31.0 46.6 50.0 72.8 21.0 35.7 22.0 64.5 40.4 26.4 42.7 30.2 73.7 76.5 28.1 38.3 57.4 53.0 47.1 45.4 66.3 60.7 45.7 53.1 43.5 44.1 25.3 30.3 47.9 23.7 44.9 32.8 33.3 126.8 94.5 96.3 23.1 106.0 22.6 23.1 22.3 19.0 83.4 31.8 20.7 20.1 129.3 42.8 125.0 43.6 37.0 70.3 44.3 80.7 62.4 56.0 47.4 51.6 73.0 63.8 71.5 55.7 60.8 119.1 22.2 28.9 30.5 35.9 25.8 28.6 24.6 24.7 12.0 17.1 25.0 17.7 12.5 15.7 30.2 23.9 39.6 27.1 30.7 79.1 5.9 27.1 22.9 26.3 26.4 22.3 16.2 12.0 38.9 26.7 29.2 23.7 32.1 47.4 18.3 29.6 15.7 24.6 30.5 13.5 40.2 39.5 24.4 50.5 40.8 12.9 16.4 52.3 16.0 39.4 51.8 13.8 14.4 48.7 395.8 38.2 58.8 15.4 23.6 38.8 76.2 13.0 29.0 28.0 26.3 20.0 19.0 40.2 14.4 20.4 33.0 49.9 21.6 18.6 41.3 51.5 PSIP1 "DFS70, LEDGF, p52, p75, PSIP2" ENSG00000164985 "PC4 and SFRS1 interacting protein 1" O75475 9 15464066-15510995 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 279.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 860.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013718, HPA019697" Enhanced Enhanced Nucleoplasm NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB013718: , HPA019697: AB_1852779" "unprognostic (8.54e-2)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.23e-1)" "unprognostic (2.89e-3)" "unprognostic (5.10e-2)" "unprognostic (5.93e-2)" "unprognostic (2.53e-2)" "unprognostic (6.49e-3)" "unprognostic (5.49e-2)" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.99e-1)" "unprognostic (7.14e-2)" "unprognostic (1.39e-1)" 32.9 40.9 67.8 46.9 72.1 62.0 27.4 83.9 89.1 45.8 52.6 40.8 23.1 57.5 36.0 26.2 42.9 30.8 34.4 71.5 79.2 32.6 22.3 32.8 80.7 65.2 66.4 86.0 17.1 30.3 52.2 39.5 64.4 36.3 30.9 154.4 19.1 41.0 38.6 26.0 34.4 43.2 65.1 54.7 28.5 81.6 68.1 129.7 37.1 29.5 69.3 31.2 32.3 72.2 117.5 76.5 254.7 187.4 54.0 65.2 56.7 138.3 98.1 121.7 143.6 32.1 59.5 248.1 31.4 73.5 68.2 32.0 160.1 75.0 174.9 164.8 96.6 860.4 194.9 60.8 65.1 101.7 91.7 54.8 21.0 102.1 74.4 121.0 108.0 115.2 144.4 134.1 80.2 42.8 211.5 250.9 395.2 2.7 117.2 194.7 138.8 50.7 68.3 40.5 161.1 176.7 123.7 54.0 67.1 157.5 54.5 134.9 76.7 88.0 88.6 66.7 133.2 57.1 85.3 221.8 70.2 100.8 51.6 13.7 2.6 5.4 6.1 2.0 7.7 11.0 12.5 8.8 3.0 17.5 18.7 11.6 8.4 9.5 5.7 3.1 12.9 2.4 67.8 72.1 83.9 89.1 71.5 79.2 65.2 66.4 64.4 65.1 68.1 72.2 93.7 54.5 31.9 27.4 98.1 31.9 49.1 8.1 48.9 231.0 22.0 35.6 57.8 31.5 23.1 47.8 66.7 122.7 82.1 24.7 62.6 9.5 95.5 92.9 62.5 84.8 38.1 160.1 73.4 8.5 76.2 74.8 23.0 35.1 15.2 104.2 65.3 18.0 32.1 138.0 76.9 34.1 2.0 36.5 45.9 58.5 125.9 45.8 40.9 20.6 47.9 162.2 83.4 49.8 67.6 3.6 20.6 134.3 60.4 19.6 14.1 54.5 42.1 279.1 124.9 85.2 89.8 217.9 243.8 34.5 21.2 41.3 111.6 68.6 45.8 20.3 PSMD4 "AF, AF-1, Rpn10, S5A" ENSG00000159352 "Proteasome 26S subunit, non-ATPase 4" P55036 1 151254709-151267479 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038807, HPA039252, CAB047300" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 69000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB047300: , HPA038807: AB_2676217, HPA039252: AB_10673418" "unprognostic (3.83e-2)" "unprognostic (7.89e-2)" "unprognostic (6.86e-3)" "unprognostic (1.70e-1)" "unprognostic (2.63e-1)" "unprognostic (2.89e-2)" "unprognostic (1.79e-3)" "unprognostic (2.16e-1)" "unprognostic (2.81e-1)" "unprognostic (2.61e-2)" "unprognostic (7.57e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (6.66e-10)" "unprognostic (9.80e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (3.91e-1)" 108.8 118.0 198.8 77.8 203.8 89.4 97.9 203.0 288.1 88.7 195.2 136.9 68.9 99.5 114.3 115.5 91.0 58.2 191.2 202.8 205.8 110.2 170.5 81.7 95.7 208.5 215.3 85.8 114.0 91.6 79.4 91.1 209.3 91.3 82.1 64.5 83.9 86.4 404.1 103.3 91.3 91.0 204.2 109.6 115.4 152.0 203.7 114.3 76.7 188.0 114.0 118.6 88.2 203.4 251.4 294.8 213.4 175.2 227.4 167.0 231.9 166.0 202.1 258.6 205.1 388.3 278.2 202.2 396.2 235.4 178.7 255.4 277.1 250.6 219.6 331.9 236.6 197.8 256.2 396.6 250.8 234.7 220.5 182.5 204.2 296.3 271.4 193.3 229.5 222.4 313.6 247.9 220.2 723.5 217.4 276.7 406.0 384.3 293.4 181.6 207.7 364.7 252.7 210.6 166.7 283.8 184.5 266.3 222.7 313.0 278.9 452.3 203.4 128.1 201.2 159.2 288.2 295.1 397.7 430.3 212.6 218.1 238.7 439.4 439.0 713.9 247.3 478.1 281.2 399.0 287.4 274.4 398.4 426.1 261.0 258.1 580.2 351.2 502.3 240.3 476.6 651.0 198.8 203.8 203.0 288.1 202.8 205.8 208.5 215.3 209.3 204.2 203.7 203.4 90.1 57.7 62.9 15.7 78.5 88.6 111.9 249.0 58.1 50.9 60.9 69.3 245.2 82.9 125.0 60.7 27.1 328.6 74.0 104.1 168.3 177.3 279.1 91.5 63.0 95.8 84.2 107.3 25.3 186.9 234.1 88.5 46.9 59.1 83.6 88.8 83.2 116.0 184.5 33.7 24.2 94.1 156.6 104.0 98.0 243.2 105.3 90.3 104.9 11.2 256.6 91.9 115.4 16.1 23.2 172.2 129.1 98.6 67.0 121.4 168.6 206.6 148.3 54.6 118.3 79.0 221.1 234.8 83.5 66.7 86.5 414.6 77.7 105.6 114.5 107.2 PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.7" "Cell type enhanced" "Detected in many" "Late spermatids: 237.5;Leydig cells: 191.0;Peritubular cells: 444.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 6.1" "Lineage enriched" "Detected in single" 9 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "NTERA-2: 29.6;WM-115: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "CAB013717: , HPA075072: AB_2686733" "unprognostic (1.46e-1)" "unprognostic (1.06e-1)" "unprognostic (3.16e-1)" "unprognostic (1.79e-2)" "unprognostic (3.22e-2)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" "unprognostic (3.54e-3)" "unprognostic (2.63e-1)" "unprognostic (8.66e-3)" "unprognostic (1.52e-2)" "unprognostic (2.82e-1)" "unprognostic (1.13e-6)" "unprognostic (8.63e-2)" "unprognostic (4.40e-2)" "unprognostic (2.76e-1)" "unprognostic (2.82e-1)" 3.0 3.5 9.5 4.0 11.6 0.7 2.8 24.6 5.6 26.7 2.7 11.3 8.1 15.6 2.7 2.9 7.1 8.1 2.9 4.7 17.8 4.6 2.2 5.5 2.2 16.0 12.7 5.0 6.4 2.5 2.1 3.8 8.0 6.8 12.3 8.3 7.5 4.0 3.0 3.2 11.6 2.4 7.0 3.3 12.5 14.5 24.0 2.1 4.7 4.8 3.0 7.2 2.9 4.5 10.1 4.7 20.3 12.9 3.0 5.0 11.4 1.9 1.7 2.2 1.4 4.9 4.8 8.0 3.3 3.8 4.4 22.3 11.7 1.6 1.4 7.9 7.8 0.0 4.8 2.3 2.7 0.2 4.2 4.7 2.4 2.2 1.4 4.3 4.2 3.5 7.3 9.1 1.0 1.9 0.1 3.2 29.6 7.2 1.8 0.0 15.5 4.2 1.6 1.5 13.8 7.0 7.1 6.8 2.9 18.8 1.8 2.1 1.1 2.6 12.9 13.6 1.5 18.0 16.8 5.3 3.8 3.9 71.0 0.0 0.0 0.0 6.1 0.0 3.3 0.7 1.1 2.5 0.0 0.2 1.9 2.2 0.0 0.3 0.0 0.0 1.2 1.7 9.5 11.6 24.6 5.6 4.7 17.8 16.0 12.7 8.0 7.0 24.0 4.5 6.0 0.0 6.4 49.0 3.0 4.0 2.7 3.0 4.6 20.3 3.5 4.6 5.9 25.8 2.7 0.0 41.7 3.0 11.8 2.0 5.9 3.5 88.4 12.2 89.8 5.4 21.7 0.4 15.2 4.2 1.9 27.2 1.1 11.0 1.3 2.6 6.4 2.9 0.8 20.2 10.7 11.0 4.1 0.9 1.2 237.5 191.0 1.4 12.4 4.7 0.8 55.6 54.6 39.7 20.5 2.4 3.1 444.5 3.1 4.9 3.1 1.6 5.5 13.4 39.5 4.8 9.4 4.4 35.5 3.0 4.4 1.4 6.5 71.7 4.7 1.4 PTCH2 ENSG00000117425 "Patched 2" Q9Y6C5 1 44819844-44843253 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "ovary: 24.6;parathyroid gland: 59.1;salivary gland: 75.2;testis: 25.6" "Cell type enhanced" "Detected in many" "Leydig cells: 107.8;Peritubular cells: 68.1;Plasma cells: 67.1;Theca cells: 138.7" "Cancer enhanced" "Detected in many" "testis cancer: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046839 Supported "Nucleoli,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoli "HPA046839: " "unprognostic (6.54e-5)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (3.65e-3)" "unprognostic (3.89e-1)" "unprognostic (7.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (8.67e-2)" "prognostic favorable (5.74e-5)" "unprognostic (2.92e-1)" "unprognostic (5.74e-6)" "unprognostic (1.55e-2)" "unprognostic (4.86e-2)" "unprognostic (6.31e-2)" "unprognostic (6.81e-2)" 4.2 3.1 6.1 0.8 3.5 9.4 3.4 6.8 6.8 5.1 3.6 3.6 1.0 6.4 1.6 0.9 4.3 2.5 1.3 3.1 4.4 1.3 1.3 1.0 2.3 2.9 4.8 24.6 1.0 59.1 9.9 0.3 2.0 3.0 0.9 3.6 75.2 1.3 2.0 3.6 1.8 1.2 1.6 2.4 2.0 25.6 6.5 0.8 4.6 0.8 0.7 3.1 3.4 4.8 0.2 0.3 1.0 2.5 0.8 0.9 1.0 0.8 1.6 0.5 0.4 0.2 0.4 1.1 0.4 0.4 0.5 0.0 1.1 0.0 0.2 2.1 1.9 0.6 1.0 0.8 0.3 0.7 1.1 0.3 0.4 1.0 0.1 1.7 0.1 1.0 0.7 1.1 0.0 0.5 1.4 2.1 0.3 0.1 0.4 1.0 0.2 0.5 0.2 0.0 1.5 0.6 0.3 0.4 0.8 0.5 0.2 1.2 0.1 0.2 0.5 1.3 0.5 1.9 11.6 3.2 0.6 3.0 0.4 2.5 1.9 0.1 0.5 0.9 1.0 1.0 0.6 0.6 1.2 1.4 0.7 0.6 0.6 0.9 0.9 3.6 0.3 0.2 6.1 3.5 6.8 6.8 3.1 4.4 2.9 4.8 2.0 1.6 6.5 4.8 2.8 0.0 1.1 14.0 13.4 0.5 0.7 1.0 0.6 0.8 4.8 8.0 1.0 7.2 1.0 1.8 2.1 2.4 6.8 7.8 0.0 5.5 2.3 9.3 13.5 2.7 11.5 1.3 23.7 1.8 1.6 14.3 28.1 8.5 0.0 4.4 0.7 7.9 6.7 8.4 27.3 4.9 2.0 24.5 2.2 8.0 107.8 17.3 0.0 5.6 3.9 2.4 2.1 9.5 2.6 2.1 2.5 68.1 67.1 0.8 13.6 0.2 1.7 1.2 13.1 5.4 5.6 5.0 3.6 0.6 1.6 2.3 7.5 138.7 5.5 0.2 PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87863625-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004076, HPA031335" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB004076: AB_390810, HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" 64.0 25.4 17.8 18.6 19.3 12.9 47.6 34.5 23.4 54.8 15.6 28.1 12.9 27.4 18.6 28.3 35.2 15.6 29.7 20.4 18.4 22.6 39.2 39.5 21.4 16.6 17.8 28.0 33.2 11.9 17.3 30.5 16.4 26.3 14.6 30.0 19.6 16.5 23.7 25.9 24.5 22.2 14.5 40.0 25.6 28.2 19.7 31.8 26.1 14.0 16.5 28.1 38.4 17.6 23.5 10.8 12.3 11.2 28.5 19.7 10.9 12.5 28.0 14.5 20.4 10.9 28.0 28.1 8.0 20.9 8.3 14.1 16.6 14.3 22.8 14.1 4.7 9.3 28.5 13.8 30.1 31.9 15.3 13.5 38.7 18.0 23.7 60.3 20.8 17.7 7.0 72.6 13.5 18.1 17.8 56.3 4.6 19.9 0.0 27.6 6.4 20.8 22.9 13.4 4.5 19.9 16.6 7.9 23.0 9.7 21.9 45.2 17.9 44.6 10.8 18.3 10.1 23.9 32.9 30.7 14.6 29.2 2.9 21.3 14.2 25.8 6.8 21.8 7.2 7.9 7.2 6.6 10.3 6.8 8.3 8.3 60.5 8.9 15.6 8.2 7.0 4.5 17.8 19.3 34.5 23.4 20.4 18.4 16.6 17.8 16.4 14.5 19.7 17.6 67.2 35.3 63.3 83.6 48.3 56.1 57.4 31.5 47.3 113.0 49.4 41.9 46.5 57.2 31.2 29.5 39.6 25.8 64.4 57.7 33.2 24.7 70.1 40.0 114.5 56.0 31.2 52.0 141.0 30.0 62.2 79.3 39.8 33.6 25.4 39.6 53.9 64.1 35.0 45.4 132.4 44.7 12.2 206.1 97.2 92.1 56.8 105.2 62.2 196.8 101.5 61.6 44.3 139.2 95.7 30.6 39.7 54.5 39.3 45.1 50.1 38.0 31.2 61.2 92.1 66.4 170.7 33.5 25.4 45.2 60.1 57.3 46.3 44.7 46.1 64.0 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.9" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1" "Cell line enhanced" "Detected in many" "ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" 12.8 2.9 3.1 10.5 3.2 9.0 6.7 4.2 4.8 5.8 5.5 108.3 10.8 6.1 2.2 67.3 43.2 9.6 12.6 7.4 5.5 9.3 3.0 11.3 4.6 6.5 5.2 2.0 1.8 2.0 4.8 2.2 6.3 21.1 24.2 0.7 4.3 6.1 2.1 152.5 17.7 16.1 6.7 8.0 20.5 0.9 7.0 2.2 3.2 4.0 11.6 175.0 15.9 11.9 0.3 0.5 0.4 0.0 113.7 89.5 0.0 115.2 156.0 1.0 1.1 0.0 0.2 4.2 5.4 19.7 0.3 7.1 0.4 10.5 0.9 0.0 0.2 73.6 0.6 0.0 32.9 5.2 298.4 46.1 1.2 5.7 0.3 0.0 42.3 0.1 0.1 0.3 2.3 0.0 0.2 6.6 1.6 0.0 0.5 0.3 1.4 8.6 14.7 0.0 0.5 0.6 0.6 9.5 0.2 0.5 0.3 8.4 1.0 0.7 0.6 1.7 0.1 0.3 0.2 0.0 0.4 31.6 0.3 28.9 12.1 23.3 0.0 13.1 0.0 2.4 0.0 0.0 20.0 3.5 0.1 0.0 5.2 2.8 10.2 1.4 0.2 21.9 3.1 3.2 4.2 4.8 7.4 5.5 6.5 5.2 6.3 6.7 7.0 11.9 0.9 0.0 6.6 0.0 5.9 9.9 2.6 7.7 0.0 0.1 1.1 1.4 1.6 4.3 2.2 42.3 0.0 0.1 0.2 0.1 0.0 0.6 0.1 109.9 10.4 24.7 1.8 18.7 0.8 0.5 0.3 10.7 2.0 191.9 208.0 0.1 61.8 0.8 26.1 0.0 0.5 0.6 4.1 15.5 20.7 0.3 1.5 55.3 3.6 16.9 11.7 0.0 7.2 1.0 0.1 0.6 0.6 0.0 0.3 2.8 0.0 0.0 0.8 0.1 0.0 1.4 3.6 0.0 0.2 18.2 58.7 0.4 3.4 0.1 1.0 0.8 PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680922 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.7;seminal vesicle: 127.4;urinary bladder: 162.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 342.9;Fibroblasts: 270.7;granulocytes: 347.6;Langerhans cells: 305.6;Macrophages: 173.1;Urothelial cells: 151.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 16 "granulocytes: 11.7" "Cell line enriched" "Detected in many" 4 "BJ hTERT+: 405.5" "Region enhanced" "Detected in many" "hippocampal formation: 15.1" "Low region specificity" "Detected in many" "CAB000113, HPA001335" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "CAB000113: , HPA001335: AB_1079712" "unprognostic (1.36e-3)" "unprognostic (9.97e-3)" "unprognostic (3.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (9.50e-2)" "unprognostic (9.03e-3)" "unprognostic (2.81e-1)" "unprognostic (3.24e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (8.04e-3)" "unprognostic (4.38e-2)" "unprognostic (8.89e-2)" "unprognostic (3.74e-2)" 17.0 7.9 1.4 13.9 2.5 116.7 3.0 1.1 4.1 62.2 2.7 14.9 2.6 8.9 0.7 6.9 5.1 31.6 11.7 1.9 1.4 10.2 8.0 34.3 8.9 2.0 1.6 2.6 2.2 5.6 3.1 8.4 1.5 25.0 9.9 0.3 1.2 127.4 0.4 1.6 3.6 12.2 1.9 2.8 14.8 0.2 1.8 5.2 3.2 6.5 0.6 162.5 2.2 2.6 0.0 21.8 0.1 0.0 2.5 2.1 0.0 93.4 405.5 0.6 3.6 15.0 17.2 0.0 0.0 0.1 2.5 12.2 0.0 7.6 1.3 0.0 0.0 0.8 2.2 0.0 13.2 0.0 0.2 0.8 2.7 11.3 28.7 1.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 5.5 1.5 0.0 1.0 0.0 0.9 2.7 0.0 0.1 1.5 19.3 0.6 13.5 0.6 0.2 0.0 0.0 27.7 0.4 2.3 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 11.7 0.0 0.4 0.0 0.0 0.0 1.4 2.5 1.1 4.1 1.9 1.4 2.0 1.6 1.5 1.9 1.8 2.6 5.2 342.9 77.7 0.0 7.4 118.8 59.1 72.8 12.5 0.0 2.6 12.8 2.5 0.0 79.7 0.0 0.0 0.2 4.2 0.3 0.0 0.8 0.2 50.0 9.9 31.1 1.2 3.6 3.8 0.2 0.3 270.7 2.0 98.9 347.6 3.8 13.6 0.2 12.1 0.0 1.0 1.0 8.2 21.0 305.6 0.0 0.0 173.1 35.6 3.7 3.4 0.1 0.0 0.0 0.1 4.9 0.1 0.0 2.0 122.6 0.2 0.3 13.1 0.3 0.0 1.8 12.8 0.1 0.4 3.3 28.4 0.5 10.8 3.7 1.2 151.6 PTH PTH1 ENSG00000152266 "Parathyroid hormone" P01270 11 13492054-13496181 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 245 "parathyroid gland: 50184.7" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 1.0;Oligodendrocyte precursor cells: 1.0;Oligodendrocytes: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000072, CAB023409, CAB026363, HPA048540" Enhanced "Secreted to blood" NA NA 28000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB000072: , CAB023409: AB_619175, CAB026363: , HPA048540: AB_2680435" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 50184.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.2 205.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 280.4;parathyroid gland: 383.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 672.0;Extravillous trophoblasts: 416.0;Horizontal cells: 526.6;Muller glia cells: 548.5;Oligodendrocyte precursor cells: 322.7;Squamous epithelial cells: 439.9" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "AF22: 1717.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 167000 1400000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" 26.2 18.2 212.9 4.1 206.4 0.1 82.3 217.0 280.4 100.0 182.0 31.4 5.4 76.8 55.3 78.2 19.2 55.9 87.7 209.6 205.2 38.4 8.5 18.4 7.4 220.3 200.5 19.0 8.4 383.5 126.1 36.2 196.3 116.1 21.6 63.4 37.4 52.5 2.2 9.1 10.1 54.0 204.2 40.4 15.7 53.8 207.6 21.4 18.9 18.8 11.4 24.8 65.1 209.1 1.2 0.0 1717.6 21.2 0.4 0.9 140.6 45.3 134.3 25.1 34.3 0.4 0.2 0.0 0.2 60.0 15.6 1.0 0.0 0.0 18.9 0.0 1.4 0.0 0.0 0.0 7.7 0.0 0.5 1.9 0.0 16.6 0.2 24.6 0.0 0.0 0.0 8.2 7.0 0.0 0.0 0.6 133.5 0.0 1.1 0.1 2.8 0.4 0.7 0.0 8.0 116.5 0.0 0.0 0.2 24.1 0.2 0.2 0.0 37.4 32.9 1.8 99.4 0.7 0.0 0.0 119.7 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.9 206.4 217.0 280.4 209.6 205.2 220.3 200.5 196.3 204.2 207.6 209.1 10.1 0.0 0.0 303.3 1.3 23.2 1.7 85.0 209.5 27.7 244.6 117.3 14.6 2.8 20.9 1.8 6.2 220.0 2.2 0.0 9.8 1.1 24.5 53.4 672.0 32.0 0.0 0.0 4.9 0.0 416.0 248.8 0.5 24.6 0.0 1.1 7.1 0.3 20.4 526.6 18.1 0.0 0.0 0.3 20.6 14.0 172.7 4.0 44.4 102.1 0.0 548.5 0.0 322.7 218.4 0.3 0.0 185.5 2.5 18.6 0.0 7.5 7.2 32.3 59.2 3.0 91.4 4.0 2.4 439.9 13.9 193.3 4.4 144.7 0.0 2.2 PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 74000 "Cluster 6: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Nucleoli rim" "Actin filaments, Cytosol" "CAB005377: AB_632401" "unprognostic (2.18e-3)" "unprognostic (1.73e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "unprognostic (4.25e-2)" "unprognostic (3.55e-2)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (8.85e-2)" "unprognostic (3.75e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.62e-2)" "unprognostic (1.80e-2)" 62.9 36.6 74.6 34.7 91.7 46.3 37.6 72.7 115.7 37.9 38.4 32.5 27.6 37.8 28.7 38.9 24.3 29.4 68.7 66.1 85.6 39.7 53.0 34.4 35.6 79.0 84.1 26.2 31.6 53.4 16.1 38.0 85.7 35.2 30.6 51.8 25.9 42.4 75.1 32.1 26.1 45.7 83.4 26.7 30.4 18.2 81.7 35.5 46.8 64.0 32.5 40.1 23.5 106.3 116.9 107.6 77.0 73.4 109.7 106.1 92.7 136.4 148.2 105.5 78.5 107.7 43.4 124.5 69.4 127.4 66.7 68.1 100.1 121.6 173.8 93.1 85.0 181.5 102.6 59.8 109.2 145.8 108.0 86.6 119.6 113.6 159.8 101.3 88.7 92.0 140.2 41.3 103.3 83.2 101.0 69.7 94.1 112.3 73.4 102.4 114.6 70.5 97.3 126.7 53.3 66.1 133.7 99.8 85.2 77.6 114.8 97.8 108.1 122.9 110.0 74.2 121.8 79.4 141.6 120.2 102.2 99.7 117.7 32.2 11.7 16.8 14.8 10.2 14.0 18.1 13.3 12.4 13.6 20.8 15.3 11.9 10.7 12.6 13.7 18.3 10.9 7.2 74.6 91.7 72.7 115.7 66.1 85.6 79.0 84.1 85.7 83.4 81.7 106.3 49.0 60.9 68.2 27.7 25.8 25.6 39.9 25.3 20.5 29.9 40.5 32.4 131.6 24.3 41.8 36.8 16.7 23.5 34.2 25.4 33.2 37.5 63.1 31.3 92.6 46.2 13.1 21.7 67.6 42.8 25.3 35.8 21.9 40.9 28.4 33.1 26.0 101.5 26.8 13.5 54.7 22.0 18.3 33.3 21.6 28.5 51.6 31.8 14.2 40.3 31.1 59.8 29.9 32.6 73.0 59.3 19.6 79.7 37.0 73.4 16.6 39.8 23.5 22.2 32.9 58.2 49.2 7.1 6.6 37.5 27.4 35.2 31.7 30.5 22.2 66.8 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 117.6;RT4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 14.0 6.7 9.9 3.0 16.6 0.3 11.7 8.1 10.8 18.8 22.4 5.2 0.8 13.1 25.5 22.2 13.0 7.7 6.1 14.2 10.6 26.6 1.4 22.9 5.2 16.7 13.1 28.7 4.9 17.5 16.8 3.3 10.5 11.0 2.4 124.3 6.6 10.6 1.0 55.9 2.6 7.9 8.2 4.0 4.1 15.8 13.8 7.6 20.8 5.0 11.5 20.7 22.7 20.4 13.8 6.8 117.6 11.5 48.2 41.9 0.0 25.0 51.0 9.4 11.7 0.1 6.8 0.0 5.3 28.0 3.3 44.4 20.6 37.9 18.0 0.3 15.1 11.4 14.6 0.0 5.9 20.5 0.1 27.2 11.8 6.8 22.4 19.7 0.0 0.0 0.0 19.2 0.0 6.2 1.8 7.4 26.5 0.0 5.1 4.1 0.0 0.0 35.6 57.2 6.8 9.8 7.4 16.4 13.3 18.8 9.6 0.7 0.0 9.1 6.9 0.2 3.3 19.8 0.0 0.0 9.5 0.0 4.0 0.0 0.1 0.0 0.1 1.3 0.9 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 9.9 16.6 8.1 10.8 14.2 10.6 16.7 13.1 10.5 8.2 13.8 20.4 5.3 48.1 223.1 165.2 0.6 109.4 25.6 26.3 79.1 11.6 11.2 8.9 1.8 11.5 52.0 47.8 91.8 0.2 0.3 0.1 3.9 5.0 23.2 16.9 49.4 3.7 4.8 0.8 67.0 3.7 0.1 28.8 4.1 7.7 5.1 7.5 3.6 0.1 0.3 1.7 39.3 1.1 8.2 1.4 10.6 20.8 45.7 4.5 19.6 51.5 0.5 20.3 0.0 75.4 200.2 6.2 2.7 32.7 3.0 16.0 0.1 10.9 27.3 179.0 13.1 10.1 20.8 25.4 20.5 97.8 99.4 0.3 6.6 14.0 0.7 52.5 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 208.6;lymphoid tissue: 329.9" "Cell type enhanced" "Detected in many" "B-cells: 525.2;dendritic cells: 1026.4;Macrophages: 534.1;monocytes: 554.9;NK-cells: 769.3;Plasma cells: 474.2;T-cells: 1049.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 209.9;HEL: 118.0;HL-60: 108.1;JURKAT: 266.4;MOLT-4: 161.1;THP-1: 87.0;U-266/70: 93.7;U-266/84: 91.2;U-698: 123.4;U-937: 94.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 24000000 "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 32.8 11.6 3.8 248.5 3.3 208.6 13.9 4.4 4.3 14.9 6.9 26.4 27.4 11.3 5.6 15.1 8.4 45.7 7.3 3.5 5.6 7.0 29.6 68.6 329.9 12.9 8.6 5.7 5.6 4.0 2.9 23.5 11.5 11.6 30.5 2.0 13.8 6.6 4.6 5.7 42.9 25.3 7.9 202.5 37.9 5.5 6.9 306.9 7.0 7.6 251.2 62.1 5.2 14.7 0.4 0.0 0.2 0.2 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.1 209.9 0.3 0.7 0.2 0.3 0.0 0.2 0.4 0.6 0.0 118.0 0.2 0.1 0.0 108.1 0.7 0.0 0.0 0.3 0.0 0.4 0.5 266.4 2.4 3.3 0.3 0.1 161.1 65.0 0.5 0.2 0.2 4.6 0.4 0.3 0.1 0.1 1.2 1.8 0.1 0.4 0.5 0.2 0.3 87.0 1.3 0.0 0.8 0.8 0.4 93.7 91.2 123.4 0.1 94.5 0.4 226.1 480.0 521.4 634.4 885.8 541.8 249.0 437.0 618.1 385.8 245.8 489.8 494.1 844.3 506.9 1015.8 57.4 508.6 1340.6 3.8 3.3 4.4 4.3 3.5 5.6 12.9 8.6 11.5 7.9 6.9 14.7 12.6 44.8 62.3 0.7 525.2 15.8 0.9 0.0 4.0 0.3 6.0 9.3 4.6 5.7 14.2 1.8 0.0 0.6 1026.4 1.0 0.0 0.7 2.4 2.3 2.3 15.1 1.2 58.8 0.7 0.0 0.9 17.2 46.9 2.7 246.5 0.1 14.6 6.9 96.0 0.0 1.7 0.4 0.0 334.9 214.5 3.5 1.2 534.1 21.4 201.4 554.9 0.1 769.3 2.5 0.7 0.1 0.8 0.0 474.2 1.1 0.1 2.5 11.7 0.2 6.6 7.4 6.7 0.3 0.6 1.8 15.2 0.8 1049.1 5.4 0.9 0.8 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 889.9;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 10.7 4.2 13.4 9.7 20.6 0.2 25.6 16.7 18.6 13.5 8.6 27.3 32.8 12.1 8.2 9.7 14.9 32.5 12.4 15.9 14.5 14.9 29.6 19.4 6.9 16.8 16.7 15.1 26.2 10.2 7.0 21.8 17.8 18.9 27.6 4.6 15.3 19.0 5.9 12.2 28.5 15.9 14.5 7.9 30.5 2.2 16.4 10.2 11.7 9.9 8.7 20.9 12.3 29.8 17.3 16.7 10.9 1.0 24.9 31.9 11.0 43.6 86.3 18.4 16.6 28.8 15.0 0.1 13.4 40.7 50.8 49.0 10.2 35.9 26.7 50.3 19.4 0.3 23.6 45.7 29.7 0.0 1.7 23.9 35.4 35.9 49.6 50.8 54.0 14.7 0.0 1.1 49.3 33.6 26.6 0.1 11.9 34.5 22.6 94.8 21.7 3.1 51.1 33.4 43.8 0.1 45.2 55.6 2.7 12.4 14.6 1.1 86.9 30.0 18.4 54.8 42.2 0.7 6.0 0.0 38.1 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 13.4 20.6 16.7 18.6 15.9 14.5 16.8 16.7 17.8 14.5 16.4 29.8 39.2 25.6 33.5 155.7 17.5 63.5 88.1 45.2 60.3 7.3 56.6 26.5 22.2 101.5 44.1 18.4 4.2 24.8 0.8 75.2 0.0 63.2 4.6 30.6 11.5 46.6 43.9 0.0 889.9 61.3 4.1 28.6 77.5 77.5 1.3 13.4 11.4 40.9 6.4 10.1 55.3 44.2 8.2 1.6 8.8 2.7 17.1 2.2 17.8 200.5 1.7 5.1 0.0 313.1 1278.1 124.2 53.8 18.0 1.0 115.8 68.7 13.4 25.9 0.7 59.2 20.1 41.5 11.3 8.9 27.0 38.1 26.8 3.4 14.1 56.6 157.0 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 193.6;Inhibitory neurons: 231.1;Oligodendrocyte precursor cells: 126.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.9;NTERA-2: 5.8;SH-SY5Y: 6.1;THP-1: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 1.8 0.8 8.7 3.0 9.4 0.2 0.8 0.0 10.3 1.3 0.1 10.4 1.7 4.8 1.4 0.4 1.0 1.2 0.5 9.8 8.9 36.3 1.3 6.8 3.1 2.2 3.3 0.4 0.4 0.3 2.4 4.4 5.3 0.5 26.8 7.5 0.5 0.8 0.3 0.4 2.0 6.6 0.9 3.4 0.8 0.5 9.5 1.2 0.3 0.5 3.2 1.5 0.4 2.9 0.0 0.1 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.5 1.3 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.8 1.2 0.0 0.0 0.0 0.0 0.1 0.2 1.5 6.1 0.9 0.0 0.1 0.1 0.1 2.7 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.0 0.1 1.2 0.0 6.0 0.0 0.0 12.3 0.0 8.9 1.7 0.4 8.5 8.6 2.8 1.2 0.1 0.1 12.7 10.9 1.4 3.2 8.7 9.4 0.0 10.3 9.8 8.9 2.2 3.3 5.3 0.9 9.5 2.9 0.2 0.0 0.5 7.5 7.0 0.3 1.3 0.5 0.0 25.2 0.0 0.1 0.7 0.0 1.8 16.5 0.0 0.2 4.0 3.9 0.0 0.4 0.0 0.8 0.2 1.1 3.6 0.0 193.6 0.0 0.2 0.9 0.0 0.6 0.0 0.0 1.1 0.2 26.1 25.2 231.1 8.3 0.0 21.1 10.6 0.6 0.6 10.5 0.0 17.8 13.8 0.6 1.0 126.7 6.3 0.1 9.8 0.4 1.0 0.1 0.1 0.2 0.0 4.8 0.0 2.1 0.7 0.6 1.1 0.1 0.4 0.3 1.0 0.1 22.4 0.8 PTPRT "KIAA0283, RPTPrho" ENSG00000196090 "Protein tyrosine phosphatase receptor type T" O14522 20 42072752-43189970 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.9;fallopian tube: 10.8" "Group enriched" "Detected in some" 14 "Excitatory neurons: 500.7;Inhibitory neurons: 700.2;Oligodendrocyte precursor cells: 418.7" "Group enriched" "Detected in many" 5 "breast cancer: 5.1;prostate cancer: 1.9" "Region enhanced" "Detected in many" "cerebral cortex: 23.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017336, CAB069423" Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB069423: AB_1622602, HPA017336: AB_1855943" "unprognostic (7.17e-3)" "unprognostic (1.02e-1)" "unprognostic (5.61e-3)" "unprognostic (1.08e-2)" "unprognostic (5.95e-2)" "unprognostic (3.71e-2)" "unprognostic (1.97e-1)" "unprognostic (1.31e-2)" "unprognostic (6.93e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-6)" "unprognostic (3.16e-1)" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.17e-1)" 0.1 0.2 10.1 0.1 10.7 0.0 2.7 0.0 23.9 0.6 0.0 0.1 0.5 0.0 0.2 0.0 10.8 0.1 0.2 7.4 0.0 0.1 0.2 1.0 0.4 0.1 0.0 0.0 0.4 0.0 3.0 2.8 0.0 0.2 0.0 3.6 1.0 2.6 0.0 0.4 0.3 0.0 0.0 0.1 0.8 1.6 0.0 6.3 0.0 0.1 0.4 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 10.7 0.0 23.9 7.4 0.0 0.1 0.0 0.0 0.0 0.0 5.0 0.4 0.0 1.1 13.1 0.0 0.9 0.0 0.0 0.0 36.2 2.6 6.9 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 3.2 0.1 0.2 0.0 0.0 500.7 0.0 0.0 1.2 0.0 0.2 0.0 3.3 6.4 0.2 0.2 5.0 700.2 0.0 0.0 0.3 0.3 12.6 0.0 0.1 0.0 8.4 0.0 10.3 0.0 418.7 8.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 18.5 2.1 0.0 0.5 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 PTTG1 "EAP1, HPTTG, PTTG, securin, TUTR1" ENSG00000164611 "PTTG1 regulator of sister chromatid separation, securin" O95997 5 160421855-160428739 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.1;lymphoid tissue: 144.9;testis: 175.6" "Cell type enhanced" "Detected in many" "Early spermatids: 770.5;Erythroid cells: 415.9;Langerhans cells: 412.3;Spermatocytes: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 218.0" "Lineage enriched" "Detected in all" 7 "T-cells: 218.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008373, HPA008890, HPA045034" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "CAB008373: AB_592493, HPA008890: AB_1079717, HPA045034: AB_2679192" "unprognostic (6.48e-2)" "unprognostic (1.03e-2)" "unprognostic (1.40e-3)" "unprognostic (4.46e-3)" "unprognostic (5.81e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (7.50e-3)" "unprognostic (5.24e-2)" "unprognostic (3.47e-2)" "unprognostic (2.13e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.23e-2)" "unprognostic (3.35e-2)" 3.7 3.5 4.2 25.2 5.3 160.1 10.9 4.1 11.5 9.6 4.0 33.9 24.6 4.8 9.6 59.7 5.0 6.1 3.5 8.1 6.6 3.0 5.3 8.7 81.5 3.9 4.8 1.8 1.5 2.3 4.3 21.2 4.2 3.1 44.1 2.4 10.3 2.7 2.5 36.0 24.1 19.2 4.0 18.6 11.8 175.6 5.3 127.0 79.3 1.3 144.9 12.5 19.9 4.7 345.4 178.2 385.8 279.5 64.4 63.3 120.8 177.5 406.1 463.4 503.5 341.1 294.9 373.3 154.7 204.2 527.5 176.1 243.5 496.1 661.2 428.3 220.3 196.7 241.8 208.6 13.0 181.5 165.6 29.6 81.5 315.4 189.5 139.9 333.4 243.3 160.7 282.3 485.4 162.3 220.7 446.1 197.5 279.3 251.4 199.4 452.4 320.7 239.6 82.6 241.0 151.3 258.6 156.3 535.6 309.3 319.9 195.7 144.8 208.3 275.9 164.9 531.3 239.2 235.6 432.3 225.9 310.4 379.6 9.7 3.2 10.3 25.5 8.7 9.6 30.9 52.3 60.6 23.9 23.5 12.7 31.4 3.0 14.6 5.8 22.6 218.0 19.8 4.2 5.3 4.1 11.5 8.1 6.6 3.9 4.8 4.2 4.0 5.3 4.7 11.8 6.4 21.5 0.0 40.0 247.9 64.5 163.6 142.3 3.4 15.8 40.5 4.0 4.3 31.1 5.5 0.0 125.4 38.3 17.7 3.9 5.8 770.5 22.7 9.3 20.6 6.0 415.9 1.3 5.3 196.2 35.6 28.1 16.7 37.5 66.2 18.5 7.1 87.5 0.0 1.6 39.2 126.1 36.3 412.3 105.1 11.1 39.1 87.2 0.0 24.7 3.5 6.2 0.0 0.6 3.0 10.7 7.9 91.4 54.1 9.0 2.0 17.1 1.0 6.6 18.6 43.2 708.0 57.3 232.0 156.1 31.9 73.7 16.8 70.3 50.3 PURA "PUR-ALPHA, PUR1, PURALPHA" ENSG00000185129 "Purine rich element binding protein A" Q00577 5 140107777-140125619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Horizontal cells: 220.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 260000 "Cluster 15: NK-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "unprognostic (2.69e-1)" "unprognostic (1.23e-1)" "unprognostic (2.36e-1)" "unprognostic (3.72e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-1)" "unprognostic (1.43e-1)" "unprognostic (1.09e-1)" "unprognostic (2.41e-1)" "unprognostic (2.33e-1)" "unprognostic (3.04e-1)" "unprognostic (9.28e-2)" "prognostic favorable (4.77e-5)" "unprognostic (2.75e-1)" "unprognostic (4.24e-1)" "unprognostic (8.98e-2)" "unprognostic (2.09e-1)" 7.6 9.0 29.6 8.1 19.3 2.5 5.2 11.3 18.6 8.5 0.0 6.4 10.0 6.9 5.5 5.7 5.6 5.6 8.4 14.4 22.7 12.2 8.6 6.8 6.0 24.2 21.4 10.1 7.2 13.5 4.8 8.1 23.6 9.5 4.4 12.6 9.7 8.0 9.6 7.3 9.0 5.6 24.0 9.8 9.4 5.2 26.7 5.8 11.7 8.2 5.7 5.9 4.8 25.8 15.1 9.2 3.7 21.5 9.3 13.4 20.1 32.5 13.4 15.0 11.7 19.2 15.5 15.8 25.2 12.7 10.0 13.4 8.9 18.6 12.7 25.7 28.0 11.8 13.1 6.7 5.8 9.6 19.0 6.2 8.9 14.1 8.5 9.7 4.3 11.3 11.1 16.4 7.7 18.6 15.3 12.1 4.7 5.0 23.3 15.4 14.6 11.3 9.4 11.9 11.7 12.1 16.5 19.1 18.7 3.6 17.2 9.2 15.2 26.8 19.5 9.5 23.4 26.0 13.5 16.8 12.7 10.5 22.7 6.4 1.8 3.4 2.8 1.2 2.1 3.0 3.1 3.2 1.6 3.7 2.7 3.4 0.9 5.2 1.5 2.5 2.9 1.0 29.6 19.3 11.3 18.6 14.4 22.7 24.2 21.4 23.6 24.0 26.7 25.8 82.2 51.3 43.3 28.4 43.5 34.3 48.5 15.0 54.1 162.0 58.5 62.2 76.2 62.9 21.7 77.3 125.1 47.2 53.6 48.8 13.7 22.2 25.4 46.2 66.4 71.2 62.9 27.8 45.3 25.4 44.4 57.5 49.5 40.8 25.4 35.9 77.4 62.1 26.4 220.4 46.0 47.9 12.2 32.3 26.2 10.0 76.4 29.2 37.4 34.7 27.0 95.1 49.4 27.2 43.4 26.4 33.9 102.0 43.5 61.7 57.6 48.9 22.5 106.7 72.3 99.8 76.7 38.6 38.7 39.7 45.5 43.4 49.9 52.7 44.0 48.8 PZP CPAMD6 ENSG00000126838 "PZP alpha-2-macroglobulin like" P20742 12 9148840-9208395 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 81.6" "Group enriched" "Detected in some" 4 "Early spermatids: 26.2;Hepatocytes: 26.4;Late spermatids: 11.0;Oligodendrocyte precursor cells: 8.5;Respiratory ciliated cells: 24.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0;liver cancer: 0.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 9 "HeLa: 5.7;SiHa: 2.5" "HPA041403, HPA041471" Supported "Secreted to blood" NA NA 15000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA041403: AB_10804003, HPA041471: AB_10795636" "unprognostic (8.48e-3)" "unprognostic (1.12e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-4)" "unprognostic (4.79e-1)" "unprognostic (3.50e-2)" "unprognostic (2.04e-4)" "unprognostic (4.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (9.71e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-5)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (9.81e-3)" 0.2 0.0 0.4 0.0 1.3 0.1 0.2 0.9 0.6 0.2 0.6 0.0 0.0 1.3 0.1 0.0 1.2 0.0 0.7 0.9 0.6 0.2 81.6 0.8 0.0 2.3 6.7 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 0.6 0.0 2.3 1.0 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.1 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.9 0.6 0.9 0.6 2.3 6.7 3.9 0.9 1.0 1.3 1.9 3.2 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.8 0.0 0.0 1.6 0.0 2.7 0.0 2.1 0.0 1.4 0.0 0.0 0.0 26.2 4.7 0.2 2.1 0.0 0.0 3.7 0.0 0.0 0.1 0.0 1.7 0.0 0.0 1.8 26.4 0.0 0.0 2.9 0.0 0.0 0.3 0.0 11.0 0.0 0.2 0.0 2.8 0.0 0.0 2.1 8.5 4.6 0.0 0.0 0.4 0.7 0.0 0.0 0.0 24.7 0.6 0.0 0.3 0.4 0.5 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 QKI QK3 ENSG00000112531 "QKI, KH domain containing RNA binding" Q96PU8 6 163414000-163578592 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Translation regulation, Transport" "Developmental protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 628.6" "Cell type enhanced" "Detected in many" "Astrocytes: 1140.0;Microglial cells: 713.0;Oligodendrocyte precursor cells: 1421.0;Oligodendrocytes: 4573.8" "Cancer enriched" "Detected in all" 6 "glioma: 42.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 250.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019123, CAB022602" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB022602: , HPA019123: AB_1855980" "unprognostic (2.42e-1)" "unprognostic (5.81e-2)" "unprognostic (1.31e-1)" "unprognostic (1.06e-2)" "unprognostic (8.57e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.34e-1)" "unprognostic (7.06e-2)" "unprognostic (1.76e-3)" "unprognostic (1.08e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.16e-1)" "unprognostic (3.86e-1)" "unprognostic (4.09e-2)" 76.3 24.2 208.2 36.8 437.7 69.7 27.8 355.8 207.9 29.2 2.5 22.2 7.9 28.4 8.7 34.4 25.3 33.8 149.3 211.1 301.1 22.7 41.1 55.9 27.4 431.2 367.9 38.2 16.0 15.0 6.9 53.0 451.4 15.3 16.7 26.9 15.3 22.3 157.0 18.6 11.9 46.3 304.5 39.8 12.1 47.3 365.7 28.5 22.1 222.1 25.3 38.2 16.4 628.6 17.8 72.0 250.8 83.7 74.3 81.9 58.4 46.8 109.0 74.5 89.4 49.3 15.8 21.3 38.6 117.2 50.8 25.9 134.4 48.4 120.2 43.7 43.3 83.4 38.4 55.3 90.4 44.8 24.9 96.8 19.5 80.0 125.8 72.4 104.4 30.9 124.3 48.2 48.6 32.8 30.1 9.5 32.4 17.3 36.0 45.9 156.5 42.3 40.5 54.4 5.2 28.7 49.9 26.7 19.2 101.2 10.5 71.8 107.2 51.3 42.7 55.9 86.1 30.9 40.9 26.3 44.2 38.7 122.8 3.6 7.1 3.4 1.8 4.7 3.0 1.2 1.3 1.6 3.7 1.2 1.1 2.0 9.2 6.3 5.1 6.2 1.0 1.1 208.2 437.7 355.8 207.9 211.1 301.1 431.2 367.9 451.4 304.5 365.7 628.6 180.6 150.6 51.5 1140.0 35.4 153.7 34.1 25.3 43.9 60.4 42.8 47.2 355.5 37.1 30.5 20.2 58.4 51.1 77.7 0.2 21.5 21.8 53.0 60.7 156.7 130.0 0.0 40.4 58.4 12.0 51.3 92.2 10.2 71.1 60.9 64.8 131.0 72.9 86.8 32.0 471.4 0.0 14.2 221.9 188.0 102.5 86.6 165.7 113.8 713.0 107.9 113.5 32.0 1421.0 4573.8 19.8 0.1 98.6 34.4 46.5 0.0 33.2 23.7 31.5 46.0 197.7 83.5 46.1 19.7 47.4 136.1 55.1 32.2 69.9 0.2 46.4 RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" 27.9 32.3 18.0 5.3 18.9 7.0 19.5 21.3 22.6 29.6 7.6 35.1 9.0 31.3 5.5 12.3 27.5 7.4 31.4 21.7 14.0 151.1 37.3 25.2 5.8 14.4 15.8 33.8 47.4 15.9 41.5 6.5 15.2 29.9 3.1 6.1 19.3 7.8 52.2 19.5 27.5 7.1 12.7 26.4 22.2 34.6 16.8 5.3 24.8 15.8 3.2 31.7 19.9 19.0 5.9 14.9 14.6 11.9 20.2 13.2 10.0 10.6 11.6 10.7 7.6 11.5 3.0 15.3 11.0 18.7 8.9 5.5 8.9 13.4 3.9 10.8 14.9 7.9 14.8 31.7 20.9 9.5 8.6 12.7 8.8 11.6 9.9 11.7 17.3 10.7 3.5 6.0 14.4 22.5 10.2 15.9 11.7 5.0 6.8 22.8 10.8 4.6 11.3 4.0 13.8 12.0 11.5 13.6 7.5 5.0 7.6 13.9 29.9 14.8 8.8 13.6 7.0 6.9 6.7 18.8 6.5 5.8 11.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 18.0 18.9 21.3 22.6 21.7 14.0 14.4 15.8 15.2 12.7 16.8 19.0 9.4 3.2 1.7 36.9 3.8 3.7 0.7 1.1 2.2 7.7 3.5 4.3 12.4 7.2 4.3 5.5 6.2 1.0 5.7 5.9 27.4 1.6 1.2 6.4 8.7 7.1 3.0 1.7 73.5 1.2 0.2 5.5 2.0 13.1 1.3 8.4 17.9 15.9 0.8 21.9 60.3 3.0 0.0 3.7 1.6 2.6 0.6 4.7 0.0 19.7 0.6 7.2 2.1 46.8 40.7 1.4 3.9 1.9 3.4 0.9 8.1 384.2 3.1 7.6 6.6 5.3 5.4 4.0 2.8 0.3 2.3 0.8 4.4 6.1 5.9 0.3 RAB18 ENSG00000099246 "RAB18, member RAS oncogene family" Q9NP72 10 27504174-27542239 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Protein transport, Transport" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025928 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 30: Mammary glandular cells - Lactation" "HPA025928: AB_1855997" "unprognostic (9.45e-3)" "unprognostic (7.71e-2)" "unprognostic (2.95e-1)" "unprognostic (6.71e-2)" "unprognostic (3.37e-2)" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (1.17e-1)" "unprognostic (3.64e-1)" "unprognostic (1.27e-2)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (1.71e-3)" "unprognostic (9.55e-2)" "unprognostic (1.01e-1)" "unprognostic (1.39e-1)" "unprognostic (8.48e-2)" 40.8 55.5 26.3 29.0 26.8 88.9 50.7 28.9 32.1 32.3 26.5 34.3 33.5 30.5 41.0 44.5 25.4 26.7 48.0 26.4 33.4 47.5 52.3 30.0 26.2 28.5 30.2 30.8 31.5 53.2 20.4 36.7 31.8 41.2 35.2 70.6 28.0 34.1 51.2 35.7 30.9 37.4 30.9 30.0 32.0 34.3 30.1 34.9 41.1 50.5 32.9 39.7 31.0 33.5 68.1 47.5 56.8 41.0 94.1 53.3 37.9 102.6 47.0 87.6 83.4 46.2 44.6 27.7 42.7 88.8 44.2 44.9 37.4 65.6 72.0 42.3 34.1 39.2 44.2 59.3 68.0 16.9 45.4 70.5 122.2 55.0 31.4 62.3 68.5 25.7 22.6 55.2 75.0 44.1 37.8 11.6 24.8 38.7 22.1 27.3 93.8 33.7 83.5 37.6 30.5 36.9 50.6 57.1 67.5 59.6 115.6 35.0 68.5 40.0 49.9 76.8 60.1 24.0 47.5 34.7 68.6 97.6 22.6 212.9 54.4 137.4 41.7 50.7 91.5 25.6 35.7 45.1 40.6 26.5 30.1 35.9 193.2 45.2 60.9 26.7 42.7 49.8 26.3 26.8 28.9 32.1 26.4 33.4 28.5 30.2 31.8 30.9 30.1 33.5 50.3 73.7 44.5 37.5 51.4 186.0 105.3 145.9 68.9 74.1 131.7 51.2 131.4 48.6 92.9 90.1 41.7 90.5 64.9 82.3 213.2 105.0 46.7 46.7 55.4 62.1 65.4 41.2 53.9 90.4 114.9 78.7 31.6 51.8 34.9 63.6 62.8 85.1 84.5 48.8 51.2 47.5 152.5 81.0 83.4 33.8 63.0 62.4 99.6 42.2 115.6 117.6 53.5 43.7 54.8 120.5 57.8 69.2 51.3 127.6 73.1 208.6 72.8 91.0 26.3 45.9 76.9 138.7 81.0 80.7 199.0 149.1 60.9 79.1 40.9 132.6 RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Paneth cells: 249.6;Squamous epithelial cells: 300.6;Undifferentiated cells: 244.6;Urothelial cells: 232.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "BEWO: 120.9;CAPAN-2: 119.9;MCF7: 171.5;OE19: 392.3;RT4: 153.4;SK-BR-3: 243.3;T-47d: 227.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010872, CAB033645" Enhanced Uncertain "Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions, Cytosol" "CAB033645: AB_1128883, HPA010872: AB_1079729" "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" 0.6 0.1 0.1 10.2 0.1 0.1 52.0 0.3 0.3 76.2 0.0 86.2 72.9 7.3 37.5 423.3 47.5 26.4 0.1 0.0 0.0 41.6 1.7 39.2 0.4 0.1 0.1 0.4 57.1 68.9 27.5 12.4 0.1 36.3 78.1 0.0 105.3 28.4 0.9 210.0 65.6 3.7 0.2 0.2 80.9 0.3 0.1 10.1 50.6 0.0 44.0 69.9 148.2 0.3 93.3 0.0 0.0 0.0 0.0 0.0 120.9 0.0 0.0 0.0 0.0 90.4 119.9 0.0 0.1 0.0 0.0 109.5 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 105.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 171.5 0.0 0.4 4.8 392.3 0.0 0.1 0.0 0.3 0.0 153.4 13.3 0.0 0.0 243.3 0.3 21.1 227.9 0.4 0.0 0.2 0.2 0.0 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 1.2 28.9 41.0 0.0 1.5 55.1 102.9 113.9 74.0 0.0 121.4 137.7 0.1 94.4 98.7 86.5 0.0 102.1 2.3 197.8 166.3 170.4 0.0 58.6 6.4 2.6 85.4 0.0 0.1 150.3 30.0 2.3 96.4 66.2 5.7 0.0 0.0 0.4 7.3 0.0 0.1 208.5 89.5 0.0 5.8 0.0 0.3 2.1 21.4 0.0 3.6 0.0 0.0 0.0 0.1 197.3 249.6 0.0 0.3 114.0 195.9 35.5 66.3 0.0 0.0 0.0 6.8 0.2 1.1 300.6 154.7 80.3 2.7 0.0 244.6 232.3 RAB40A "Rar-2, RAR2A" ENSG00000172476 "RAB40A, member RAS oncogene family" Q8WXH6 X 103499130-103519489 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 8.0" "Group enriched" "Detected in some" 5 "Astrocytes: 4.9;Excitatory neurons: 7.4;Inhibitory neurons: 7.3;Microglial cells: 5.6;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 3.3;Peritubular cells: 6.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.3;NTERA-2: 3.7" HPA076172 Uncertain Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA076172: " "unprognostic (3.49e-1)" "unprognostic (6.01e-2)" "unprognostic (4.33e-2)" "unprognostic (4.49e-3)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-1)" "unprognostic (4.05e-1)" "unprognostic (3.82e-2)" "unprognostic (4.43e-1)" "unprognostic (7.36e-4)" "unprognostic (7.85e-3)" "unprognostic (9.39e-5)" "unprognostic (1.43e-1)" "unprognostic (1.11e-3)" 2.0 1.2 1.0 0.2 3.1 0.1 0.9 0.7 1.4 3.0 6.4 0.6 0.4 4.5 8.0 7.1 2.3 0.5 0.7 1.6 1.2 1.3 0.3 1.3 0.2 0.8 0.3 4.6 0.5 0.2 2.4 0.6 0.3 3.5 0.3 1.3 0.4 2.1 0.2 0.5 0.5 0.9 0.0 0.6 0.8 3.8 1.1 0.1 0.7 0.2 0.1 2.3 1.5 1.0 0.2 0.9 3.3 0.1 0.7 0.9 1.6 1.0 0.2 0.1 0.3 0.7 0.5 0.8 1.2 0.2 1.0 0.0 0.2 0.0 0.1 0.0 2.0 0.2 1.8 0.2 0.3 0.0 0.1 0.7 0.1 0.3 0.2 1.2 0.2 0.3 1.2 0.5 0.3 0.2 0.2 0.1 3.7 0.0 0.5 0.0 0.2 0.0 0.0 0.3 1.4 1.7 0.3 0.0 0.7 0.9 0.0 0.1 1.7 1.3 0.8 2.1 0.9 0.6 0.4 0.6 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.1 0.7 1.4 1.6 1.2 0.8 0.3 0.3 0.0 1.1 1.0 0.3 0.0 0.0 4.9 0.0 0.0 0.7 0.1 0.0 0.2 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.6 0.1 0.0 0.0 7.4 0.0 0.2 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 7.3 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 5.6 0.0 0.2 0.0 6.6 3.3 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004549: AB_628192, HPA019669: AB_1856019, HPA024235: AB_1856020, HPA024691: AB_1856021" "unprognostic (3.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-1)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.25e-2)" "unprognostic (3.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (7.73e-2)" "prognostic favorable (6.43e-4)" "unprognostic (1.14e-1)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (9.00e-3)" 30.1 23.6 39.1 23.2 45.8 17.1 43.9 41.0 49.3 22.2 32.0 21.1 16.5 26.8 25.1 18.5 16.7 21.7 32.4 37.9 46.7 23.5 32.8 19.5 33.5 43.1 44.8 21.7 18.0 48.0 19.7 30.8 44.2 31.0 20.7 58.2 22.7 21.8 68.5 16.3 18.9 27.5 43.5 28.3 24.0 18.8 43.7 37.3 25.8 52.4 40.3 23.1 15.2 50.7 45.5 57.5 59.6 33.3 60.9 60.5 31.2 58.3 44.5 61.8 58.5 51.4 19.7 98.3 46.0 61.2 35.0 35.9 87.8 50.0 86.4 60.7 75.0 60.9 73.1 39.4 56.4 41.3 37.9 47.2 33.3 59.6 76.5 37.7 54.4 49.9 52.3 48.3 54.2 32.7 66.1 30.4 26.8 25.8 24.9 61.2 70.8 32.4 30.6 43.1 25.3 39.4 52.4 52.8 49.5 52.3 95.9 17.2 46.9 53.1 24.2 52.6 69.6 26.9 31.0 52.4 41.2 62.3 37.5 14.9 21.1 22.4 25.0 22.7 21.9 80.4 19.5 24.0 22.6 96.7 24.6 21.5 30.4 22.6 50.9 35.0 20.0 16.6 39.1 45.8 41.0 49.3 37.9 46.7 43.1 44.8 44.2 43.5 43.7 50.7 36.4 35.3 45.1 57.5 53.8 24.0 30.1 17.0 25.6 51.5 87.3 46.0 91.1 14.3 32.9 18.4 39.6 39.7 47.2 18.6 41.1 30.4 7.6 19.8 55.5 37.9 16.3 58.3 123.7 23.8 35.0 38.5 23.4 25.3 12.6 47.0 34.2 31.7 89.8 35.3 115.9 17.1 30.5 32.1 38.2 6.0 33.8 36.5 30.2 90.9 32.8 89.7 63.8 78.4 114.1 28.3 65.5 28.2 28.2 52.8 16.5 38.1 19.0 52.5 26.3 34.3 47.7 82.2 75.7 25.5 20.3 25.9 34.4 61.2 18.9 33.6 RAC1 "p21-Rac1, Rac-1, TC-25" ENSG00000136238 "Rac family small GTPase 1" P63000 7 6374527-6403967 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 1980.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035994, HPA047820" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 3900000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Nucleoli "CAB035994: , HPA047820: AB_2680167" "unprognostic (8.66e-3)" "unprognostic (2.47e-1)" "unprognostic (4.00e-1)" "unprognostic (2.40e-2)" "unprognostic (1.88e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (1.74e-5)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.63e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.95e-1)" "unprognostic (2.11e-2)" "unprognostic (4.13e-2)" "unprognostic (8.72e-3)" 157.4 108.0 237.0 96.8 250.4 94.5 146.4 242.4 290.7 154.8 206.5 190.5 167.4 150.7 149.9 316.9 145.1 125.9 129.4 240.2 240.6 150.5 136.2 147.5 96.4 249.4 244.8 135.8 92.2 151.1 77.5 180.2 249.2 122.8 199.6 52.2 137.9 145.0 179.5 189.2 161.9 179.3 260.2 96.6 160.6 51.6 241.1 115.3 127.2 141.1 169.6 205.3 188.6 262.9 519.9 230.9 233.0 255.1 270.1 341.8 138.6 284.9 348.0 371.6 375.8 227.3 474.8 145.5 179.7 400.9 384.2 359.4 251.5 345.9 471.9 68.3 207.8 146.6 171.7 166.5 323.7 134.0 114.6 229.7 302.8 268.4 297.6 281.7 333.4 141.3 266.2 111.7 406.4 377.3 74.0 312.4 419.1 261.9 272.3 129.2 236.9 214.6 481.7 322.7 175.8 295.9 201.7 726.1 241.4 264.7 409.6 396.3 341.8 242.4 364.3 300.7 334.5 84.1 99.5 135.4 223.9 250.9 470.6 31.0 117.3 63.0 23.8 83.0 15.1 46.8 26.8 30.9 112.8 49.9 33.0 21.8 168.6 26.1 83.5 64.5 46.1 47.0 237.0 250.4 242.4 290.7 240.2 240.6 249.4 244.8 249.2 260.2 241.1 262.9 755.4 147.4 123.6 28.7 155.9 934.1 981.6 232.1 429.2 90.4 485.3 593.8 200.6 484.7 164.8 356.8 25.0 802.8 224.1 920.9 536.1 183.5 77.6 388.7 362.9 641.2 336.7 313.3 43.3 174.2 1064.1 415.9 305.3 422.8 130.9 325.4 580.8 367.1 832.0 146.4 35.3 632.9 179.0 811.3 1066.7 58.8 476.3 705.7 458.9 66.5 607.2 341.1 191.6 23.1 56.7 299.1 754.4 472.8 212.2 1495.5 816.4 832.0 214.1 64.2 479.9 346.6 466.6 216.6 373.1 774.5 1148.6 845.4 180.0 353.6 573.7 1980.7 RAD21 "hHR21, KIAA0078, SCC1" ENSG00000164754 "RAD21 cohesin complex component" O60216 8 116845934-116874776 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020044, CAB022065, HPA073277" Supported Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB022065: , HPA020044: AB_1856035, HPA073277: " "unprognostic (7.85e-2)" "unprognostic (4.92e-1)" "unprognostic (3.05e-1)" "unprognostic (5.43e-3)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.86e-3)" "unprognostic (8.99e-2)" "unprognostic (8.80e-2)" "unprognostic (5.58e-3)" "unprognostic (3.56e-2)" "unprognostic (4.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" 75.4 80.5 62.9 74.0 74.5 206.0 71.9 74.7 75.7 50.5 56.7 73.1 57.3 67.6 54.6 71.2 50.6 49.4 89.8 58.1 74.3 68.2 64.7 67.9 122.8 70.0 69.3 67.8 41.9 82.3 33.8 90.1 75.2 57.5 82.5 114.2 56.9 65.0 76.6 54.0 60.4 60.2 71.9 75.5 56.4 88.7 67.2 177.2 80.9 95.5 119.5 59.7 44.5 97.1 301.6 143.9 277.3 156.7 136.5 117.0 124.2 202.1 191.4 220.8 202.4 119.8 275.2 438.6 109.4 146.0 117.4 162.4 238.5 132.1 257.6 589.1 153.1 447.6 167.2 153.7 85.5 145.7 253.1 100.2 106.0 129.4 156.0 146.1 176.4 625.8 183.6 595.6 193.1 181.1 665.4 86.2 163.6 385.4 179.2 241.8 201.5 223.4 133.5 173.3 348.2 179.1 212.2 569.4 140.6 144.5 238.3 178.5 128.5 154.6 223.5 164.4 217.1 313.3 383.9 391.9 132.8 206.7 189.7 35.3 7.9 28.0 17.4 8.7 17.5 14.4 20.3 20.6 9.0 12.8 20.8 20.6 29.7 14.3 12.7 7.6 43.7 11.4 62.9 74.5 74.7 75.7 58.1 74.3 70.0 69.3 75.2 71.9 67.2 97.1 115.7 256.4 157.1 24.5 111.2 95.6 77.5 62.5 78.0 75.4 65.8 53.0 155.2 51.5 101.0 55.2 31.3 142.4 118.1 90.4 43.0 54.0 258.0 67.0 86.7 97.0 84.4 249.8 39.3 44.9 157.0 89.4 57.1 88.2 153.5 112.9 75.0 72.1 67.9 67.3 48.1 72.7 69.2 93.1 100.0 424.9 116.5 93.4 69.4 45.9 110.8 112.5 77.2 41.2 58.3 63.5 66.3 106.5 124.0 100.0 35.7 59.4 70.5 67.9 72.3 88.6 85.3 33.2 88.6 103.7 100.4 113.7 134.1 85.5 94.1 95.5 RAD23A "HHR23A, MGC111083" ENSG00000179262 "RAD23 homolog A, nucleotide excision repair protein" P54725 19 12945855-12953642 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 984.0;tongue: 447.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 901.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026418, HPA053901, HPA057003, HPA065599" Approved Supported Nucleoplasm,Cytosol NA NA 3400000 "Cluster 27: Non-specific - Gene expression" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Cytosol "HPA026418: AB_2732430, HPA053901: AB_2682300, HPA057003: AB_2683309, HPA065599: AB_2685516" "unprognostic (2.09e-1)" "unprognostic (1.58e-3)" "unprognostic (1.23e-3)" "unprognostic (7.90e-3)" "unprognostic (1.45e-1)" "unprognostic (1.48e-1)" "unprognostic (3.78e-3)" "unprognostic (3.57e-3)" "unprognostic (3.13e-1)" "unprognostic (3.12e-3)" "unprognostic (1.09e-1)" "unprognostic (4.08e-2)" "unprognostic (2.09e-3)" "unprognostic (2.32e-3)" "unprognostic (9.99e-2)" "unprognostic (8.56e-2)" "unprognostic (6.59e-3)" 79.2 63.4 77.8 49.4 79.8 85.8 71.0 78.1 95.7 59.2 71.0 91.6 48.4 65.0 31.2 70.0 64.1 38.2 132.4 80.5 79.8 54.1 70.4 66.4 55.9 80.5 76.7 56.2 76.7 66.1 47.7 55.5 80.1 57.5 35.8 24.5 68.0 52.5 984.0 72.6 52.8 54.8 77.0 54.5 66.4 48.7 79.4 53.0 54.9 447.9 44.0 78.5 57.1 82.0 138.0 52.6 55.7 57.4 91.5 104.1 94.7 66.1 130.2 152.6 137.2 59.8 95.3 117.3 150.0 99.4 104.4 102.7 78.0 137.7 55.9 170.0 109.8 47.2 57.3 58.3 181.7 102.1 130.7 107.9 199.6 110.1 208.9 89.7 105.4 188.0 124.1 102.1 138.2 139.8 126.6 124.2 76.5 124.6 135.6 65.4 59.4 189.6 118.9 53.8 104.3 81.8 75.4 129.1 145.8 40.2 100.4 173.7 82.5 214.9 57.4 263.3 203.9 148.2 133.8 86.0 177.9 193.3 183.2 31.3 76.3 64.9 81.1 102.4 87.3 77.5 66.8 69.1 68.3 73.5 63.3 73.4 9.2 79.1 105.3 86.0 82.0 69.1 77.8 79.8 78.1 95.7 80.5 79.8 80.5 76.7 80.1 77.0 79.4 82.0 120.2 86.6 56.2 11.8 127.6 120.4 176.8 165.2 122.3 51.7 110.3 121.3 59.5 108.7 108.4 55.2 20.9 212.0 99.6 95.7 166.3 179.5 193.1 74.3 76.9 120.4 87.3 901.4 22.0 191.0 240.1 101.4 101.9 74.1 111.5 77.7 86.4 96.2 175.3 52.2 22.9 138.5 136.3 88.3 170.3 44.1 118.4 119.6 142.3 12.2 182.5 73.9 94.7 15.6 25.8 184.1 119.0 114.0 159.0 351.3 139.9 163.3 91.1 56.1 111.7 138.3 129.3 263.6 179.6 153.3 146.5 244.8 113.0 117.8 154.8 211.1 RAD23B "HHR23B, HR23B, P58" ENSG00000119318 "RAD23 homolog B, nucleotide excision repair protein" P54727 9 107283137-107332192 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 420.5;Late spermatids: 1201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029718, HPA029720, CAB033868" Enhanced Supported Nucleoplasm,Cytosol No No 5900000 "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB033868: AB_1128418, HPA029718: AB_10600116, HPA029720: AB_10601008" "unprognostic (3.95e-3)" "unprognostic (1.01e-2)" "unprognostic (2.28e-2)" "unprognostic (8.14e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (2.94e-1)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.34e-1)" "unprognostic (3.72e-1)" "unprognostic (3.31e-2)" "unprognostic (1.20e-1)" "unprognostic (2.94e-3)" "unprognostic (2.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" 73.8 47.8 26.6 44.4 27.0 82.8 48.5 40.4 37.4 42.8 22.0 47.7 41.9 41.9 68.8 63.6 40.9 34.1 48.7 29.0 29.2 44.4 140.8 39.3 39.4 26.9 27.0 37.8 64.5 50.4 30.5 77.7 26.3 48.2 47.7 42.1 38.4 43.5 153.0 64.7 40.6 55.0 22.5 36.2 41.5 59.4 27.7 58.4 42.6 123.5 49.9 67.5 42.8 30.7 132.9 114.9 158.6 102.9 107.5 166.6 179.9 200.6 162.3 172.8 116.9 190.1 140.5 184.8 79.3 218.6 156.4 181.2 221.0 175.9 172.9 126.4 73.0 96.2 112.0 147.6 140.3 174.2 79.3 141.1 161.3 165.3 248.0 136.0 124.3 79.6 158.3 133.6 159.5 215.0 169.6 88.3 170.5 231.2 133.0 125.3 209.6 87.8 149.8 122.1 144.9 98.2 138.8 193.1 125.8 237.5 197.7 70.5 114.3 129.0 127.0 161.6 152.5 91.9 181.2 98.5 138.0 101.7 138.0 0.9 1.1 1.1 1.9 1.2 2.1 1.8 1.1 1.6 1.0 2.1 1.7 1.5 2.9 2.3 0.8 1.1 2.2 0.6 26.6 27.0 40.4 37.4 29.0 29.2 26.9 27.0 26.3 22.5 27.7 30.7 49.7 44.8 40.4 32.3 54.7 195.5 148.1 40.5 79.1 40.5 65.3 36.6 117.4 68.6 42.2 35.0 27.1 269.7 37.1 82.9 50.9 89.2 420.5 69.8 80.8 68.7 101.0 76.1 54.9 77.4 259.7 79.3 60.6 90.8 36.2 83.0 55.6 209.9 99.5 50.5 47.2 83.8 38.7 65.6 131.1 1201.4 75.5 70.7 74.7 38.4 83.7 40.4 39.1 50.3 54.1 81.0 50.5 87.3 89.3 146.0 51.2 95.9 47.6 43.9 78.9 71.6 88.5 45.3 74.7 126.9 240.9 291.8 50.5 91.1 74.9 141.2 RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.7;testis: 24.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Extravillous trophoblasts: 67.2;Spermatocytes: 53.6;Spermatogonia: 24.8;Syncytiotrophoblasts: 25.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010381, HPA039310" Enhanced Supported "Nucleoli rim,Cytosol" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoli rim" Cytosol "CAB010381: AB_2253533, HPA039310: AB_2676434" "prognostic unfavorable (7.94e-4)" "unprognostic (7.20e-3)" "unprognostic (1.22e-1)" "unprognostic (2.72e-2)" "unprognostic (8.23e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (2.53e-3)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (9.59e-2)" "unprognostic (1.94e-2)" 0.9 0.6 0.4 5.5 0.5 10.5 1.9 1.7 0.7 1.0 0.6 8.3 3.2 1.2 0.4 4.2 0.7 1.3 0.6 0.4 0.5 0.5 1.3 1.1 11.0 0.4 0.3 0.6 1.4 0.5 0.2 6.8 0.5 0.8 9.1 0.3 1.0 0.3 1.0 3.1 4.1 2.4 0.1 2.4 1.8 24.3 0.3 15.7 0.6 0.5 13.3 1.7 1.5 0.5 33.8 16.1 33.4 16.3 4.4 7.8 31.1 54.9 16.5 43.3 43.8 35.4 22.1 20.4 26.8 20.9 18.9 67.7 56.6 22.1 42.3 39.0 22.2 47.7 28.2 30.4 0.4 37.9 28.5 1.7 2.9 30.0 13.5 6.4 22.5 48.5 59.6 55.8 36.6 28.5 54.4 43.6 35.2 69.2 19.0 61.0 49.0 30.7 15.4 45.3 15.4 27.0 23.6 41.4 8.5 39.2 27.0 39.4 9.9 32.8 22.2 48.7 27.2 12.0 65.1 59.8 16.3 78.0 33.5 1.3 0.6 1.7 2.4 1.3 0.6 1.7 2.5 3.2 1.0 1.1 0.6 1.2 1.2 1.8 1.4 0.9 5.9 1.2 0.4 0.5 1.7 0.7 0.4 0.5 0.4 0.3 0.5 0.1 0.3 0.5 0.0 0.0 0.0 0.3 1.9 3.6 1.5 2.0 0.0 0.8 0.1 0.0 0.9 0.0 1.0 0.0 0.0 35.3 1.4 3.0 0.0 0.0 5.7 0.2 0.2 1.0 0.0 16.0 1.6 0.0 67.2 1.3 2.0 0.2 0.0 0.6 2.2 0.2 12.7 0.0 1.2 5.3 2.0 1.6 1.7 5.3 0.6 0.5 0.0 1.0 0.3 0.3 2.1 0.5 0.6 0.1 5.0 0.7 8.2 0.9 1.0 0.0 0.1 0.0 0.0 0.5 0.9 53.6 24.8 3.9 1.6 25.3 1.2 0.1 8.0 2.1 RAD51B "hREC2, R51H2, RAD51L1, REC2" ENSG00000182185 "RAD51 paralog B" O15315 14 67819779-68730218 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Astrocytes: 150.8;Microglial cells: 263.3;Oligodendrocyte precursor cells: 157.3;Oligodendrocytes: 375.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB016191, HPA051869" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Nucleoplasm "CAB016191: AB_2238209, HPA051869: AB_2681644" "unprognostic (9.10e-3)" "unprognostic (5.45e-2)" "unprognostic (4.92e-1)" "unprognostic (6.65e-2)" "unprognostic (2.38e-2)" "unprognostic (4.85e-2)" "unprognostic (6.42e-3)" "unprognostic (2.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (6.80e-3)" "unprognostic (1.47e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-1)" "unprognostic (2.49e-2)" "unprognostic (6.79e-2)" "unprognostic (8.13e-3)" 3.1 2.3 3.0 2.9 5.7 7.3 5.5 3.8 3.3 5.8 5.8 3.0 1.1 4.4 9.0 3.7 3.9 4.3 1.7 3.4 3.7 2.7 2.1 2.7 4.8 5.7 4.7 6.3 2.1 4.9 2.0 4.1 5.7 2.5 2.6 3.0 13.1 2.3 1.2 4.2 2.4 4.4 4.3 2.6 2.6 1.8 5.0 5.9 2.5 1.2 4.3 3.6 4.5 7.3 15.3 5.9 6.5 3.9 5.9 10.0 4.0 7.6 5.8 8.2 10.5 4.2 20.1 18.6 4.8 4.7 9.4 13.4 4.1 12.1 11.1 8.4 4.2 8.9 5.4 3.3 3.2 7.6 8.6 5.1 9.0 9.4 9.9 3.8 7.4 13.5 7.3 8.4 6.7 11.9 14.9 2.7 3.8 14.6 5.9 16.6 7.7 6.8 6.3 4.3 4.4 2.9 6.0 2.2 13.1 7.6 10.1 6.8 2.0 9.9 9.6 7.8 6.3 4.0 4.4 14.9 5.5 13.1 5.7 17.4 5.7 5.7 8.1 4.8 6.6 14.2 7.6 8.6 6.5 11.8 9.4 8.9 0.7 8.5 4.7 6.4 9.4 4.5 3.0 5.7 3.8 3.3 3.4 3.7 5.7 4.7 5.7 4.3 5.0 7.3 5.1 0.0 1.1 150.8 13.3 6.6 5.1 6.4 5.7 1.8 8.4 5.1 1.6 0.0 4.0 1.8 8.4 5.4 3.5 1.1 3.9 1.9 3.0 5.3 3.7 4.5 4.8 4.6 21.5 1.4 6.7 4.2 3.1 3.6 4.5 6.8 1.8 0.8 6.5 1.7 22.0 3.8 2.0 3.4 3.5 1.9 3.7 4.2 8.8 263.3 6.8 5.8 3.1 157.3 375.2 1.0 0.6 4.5 8.9 2.4 2.7 1.8 8.4 6.0 0.0 3.6 7.0 6.2 3.2 5.6 7.0 4.0 7.0 4.4 1.8 4.6 RAD51D "HsTRAD, R51H3, RAD51L3, Trad" ENSG00000185379 "RAD51 paralog D" O75771 17 35092221-35121522 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 116.5;Late spermatids: 217.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.41e-2)" "unprognostic (3.32e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.37e-5)" "unprognostic (7.29e-2)" "unprognostic (9.59e-2)" "unprognostic (1.24e-3)" "unprognostic (1.14e-1)" "unprognostic (3.50e-2)" "unprognostic (1.73e-2)" "prognostic favorable (3.35e-6)" "unprognostic (2.34e-2)" "prognostic unfavorable (7.20e-9)" "unprognostic (7.34e-2)" "unprognostic (2.04e-1)" "unprognostic (1.73e-2)" "unprognostic (2.22e-2)" 5.7 3.9 7.3 4.2 7.8 5.0 5.4 7.1 8.9 6.5 6.6 5.5 4.5 6.3 2.8 3.9 4.8 3.8 4.4 7.7 7.3 4.9 4.3 4.6 6.0 7.4 7.6 6.6 4.9 3.7 4.1 4.8 6.8 5.0 3.7 1.8 3.5 4.6 2.8 3.3 4.6 6.0 6.8 6.5 3.9 5.7 8.0 7.9 5.8 4.7 5.9 6.0 5.2 8.2 10.0 17.4 4.4 9.0 4.1 6.7 6.1 19.1 9.8 14.2 13.4 10.4 10.9 22.4 12.5 10.8 9.3 13.5 9.8 5.8 8.3 12.4 10.8 11.2 11.6 6.6 8.5 22.3 19.7 8.6 5.8 13.5 8.9 6.8 10.5 17.8 14.7 30.7 12.1 10.8 28.0 11.2 6.3 8.8 8.2 20.9 11.1 14.3 5.4 10.2 6.7 6.7 10.3 5.2 12.1 11.1 10.7 14.7 8.6 7.0 8.5 10.5 16.0 6.0 10.7 13.2 10.2 15.5 12.4 3.5 3.6 4.0 7.9 3.5 6.0 7.2 5.0 7.1 4.0 6.7 4.7 6.0 0.7 9.2 5.1 6.5 5.1 3.9 7.3 7.8 7.1 8.9 7.7 7.3 7.4 7.6 6.8 6.8 8.0 8.2 9.1 0.0 4.8 0.0 8.5 2.3 4.7 1.6 1.8 10.4 5.6 5.6 3.3 4.3 1.5 3.7 10.4 10.8 10.9 3.2 1.9 6.4 116.5 3.3 6.6 8.7 1.2 11.1 0.0 6.8 11.0 7.0 4.6 4.0 6.3 17.7 11.4 4.7 11.0 8.4 0.0 5.0 2.0 5.7 3.1 217.6 9.6 5.8 1.8 0.0 11.0 8.0 28.8 0.0 0.0 7.0 5.7 6.8 8.7 3.7 5.3 8.5 0.8 4.2 0.0 10.7 7.8 7.9 12.6 5.4 1.4 2.9 11.1 14.0 6.3 3.0 RAD52 ENSG00000002016 "RAD52 homolog, DNA repair protein" P43351 12 911736-990053 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 34.9;Excitatory neurons: 38.0;Inhibitory neurons: 48.8;Microglial cells: 23.4;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028957 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "Plasma membrane" "HPA028957: AB_2672842" "unprognostic (4.53e-1)" "unprognostic (8.08e-3)" "unprognostic (4.68e-2)" "unprognostic (5.27e-2)" "unprognostic (7.37e-2)" "unprognostic (1.42e-2)" "unprognostic (1.82e-3)" "unprognostic (1.88e-1)" "unprognostic (2.80e-2)" "unprognostic (8.43e-2)" "unprognostic (1.03e-2)" "unprognostic (3.27e-1)" "prognostic unfavorable (2.22e-6)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (3.74e-2)" 4.9 4.7 5.9 5.0 8.2 3.6 6.0 7.8 8.4 8.8 5.1 7.2 5.8 7.3 8.4 4.7 6.6 4.2 4.7 7.1 7.0 7.6 6.4 4.0 6.3 7.2 7.3 10.8 6.6 4.9 5.2 5.4 7.6 6.2 7.0 6.8 4.4 6.0 12.3 9.8 6.6 6.1 5.3 6.0 5.5 4.4 7.8 7.0 8.3 6.8 5.9 6.1 5.8 13.7 4.0 15.2 11.6 13.8 12.1 9.7 12.7 7.9 7.5 9.0 8.7 14.8 14.3 12.8 2.4 8.2 7.4 12.0 9.4 5.4 7.7 17.7 8.2 14.6 16.2 10.0 7.0 15.6 4.2 5.5 9.4 9.1 28.3 17.6 7.4 12.4 9.8 7.5 8.6 8.7 10.8 15.7 15.4 10.0 9.9 10.8 11.6 4.8 9.4 7.1 4.3 5.0 10.3 10.8 6.0 16.8 10.2 7.5 7.4 12.3 14.6 9.8 8.6 2.7 4.6 13.5 6.3 6.9 4.5 7.0 2.1 1.5 2.9 1.9 3.5 2.9 3.0 2.5 2.7 4.0 3.3 3.2 2.0 2.6 2.5 6.0 2.9 1.0 5.9 8.2 7.8 8.4 7.1 7.0 7.2 7.3 7.6 5.3 7.8 13.7 2.5 3.2 5.9 34.9 3.4 1.8 1.4 1.7 4.0 4.2 2.7 2.7 3.6 2.8 3.2 3.7 2.1 4.8 4.5 5.9 1.9 2.3 4.0 2.3 4.5 3.4 1.8 4.2 38.0 1.6 2.8 3.3 5.1 2.6 5.7 4.5 0.7 2.6 2.5 3.3 48.8 2.0 0.0 1.0 2.9 7.5 0.6 2.6 0.0 23.4 2.8 1.4 1.0 30.2 54.5 0.9 3.4 0.7 2.3 1.6 3.9 1.8 1.7 2.6 6.6 4.2 3.9 4.0 4.7 1.9 1.0 2.1 2.6 2.2 3.3 0.8 RAD54B RDH54 ENSG00000197275 "RAD54 homolog B" Q9Y620 8 94371960-94475115 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.0" "Cell type enhanced" "Detected in many" "Astrocytes: 29.0;Cone photoreceptor cells: 27.1;Excitatory neurons: 45.8;Inhibitory neurons: 19.0;Oligodendrocyte precursor cells: 39.7;Oligodendrocytes: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.9" "Group enriched" "Detected in many" 10 "B-cells: 1.0;T-cells: 1.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA007087 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA007087: AB_1856040" "unprognostic (1.68e-3)" "unprognostic (2.51e-1)" "unprognostic (2.31e-2)" "unprognostic (8.84e-3)" "unprognostic (4.15e-2)" "unprognostic (1.44e-1)" "unprognostic (5.56e-8)" "unprognostic (1.96e-2)" "unprognostic (1.77e-2)" "unprognostic (5.39e-2)" "unprognostic (2.30e-2)" "unprognostic (2.64e-1)" "unprognostic (2.04e-12)" "unprognostic (5.86e-2)" "unprognostic (5.23e-1)" "unprognostic (9.08e-2)" "unprognostic (6.68e-5)" 0.6 0.7 1.3 1.7 2.0 2.0 1.9 2.1 2.1 2.4 1.7 1.5 1.4 1.1 2.1 1.4 5.0 0.7 0.6 1.2 1.6 0.8 1.4 0.7 2.7 1.6 1.9 1.0 0.8 0.7 1.2 1.4 1.6 1.6 2.1 7.0 0.8 2.0 0.3 1.8 1.2 1.1 1.3 0.9 1.5 3.6 1.7 4.2 1.1 0.3 3.0 1.2 0.9 1.6 20.5 15.7 20.9 11.2 1.6 2.5 11.0 16.2 8.9 22.7 23.1 8.1 14.8 14.5 25.3 4.3 11.7 12.7 18.7 7.7 24.6 17.5 11.9 23.2 8.1 7.7 1.5 8.4 8.5 0.8 1.8 11.7 14.9 4.5 8.3 14.7 16.6 8.9 24.6 10.6 28.5 5.7 13.5 23.4 14.4 7.1 21.3 8.7 8.9 9.8 12.0 8.0 11.6 2.8 9.7 17.9 14.9 6.1 5.8 14.8 7.6 16.7 18.1 4.5 12.2 7.8 7.7 15.9 15.4 0.0 0.0 0.0 0.5 0.0 1.9 0.7 0.9 0.4 0.0 1.0 0.8 1.1 0.0 0.1 0.1 0.0 0.6 0.3 1.3 2.0 2.1 2.1 1.2 1.6 1.6 1.9 1.6 1.3 1.7 1.6 0.5 0.0 0.5 29.0 1.7 0.4 0.9 1.7 1.2 9.1 1.1 1.1 1.8 1.5 0.6 3.7 27.1 2.0 0.5 0.7 1.9 0.8 0.3 11.5 1.6 1.3 1.2 3.8 45.8 0.8 3.2 1.3 3.1 5.6 0.0 3.3 3.3 2.0 1.5 0.0 19.0 1.1 0.0 0.6 0.6 0.4 3.4 0.9 0.0 9.4 0.6 4.4 1.0 39.7 25.9 0.7 0.4 2.2 3.9 0.4 0.2 1.4 3.3 17.5 0.0 1.0 1.7 9.4 13.1 3.7 0.6 0.3 2.6 3.0 2.3 0.7 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664125 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 175.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002639, HPA002640, CAB019291" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "CAB019291: , HPA002639: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 42.4 34.2 36.7 33.8 37.9 77.4 39.2 42.6 37.4 47.6 40.4 46.8 40.5 45.6 34.0 55.5 43.2 31.0 89.6 36.9 35.8 46.7 68.9 44.7 36.3 38.3 36.9 52.0 50.6 63.6 28.3 39.1 37.0 41.9 42.0 37.4 39.6 38.0 194.9 56.0 43.4 45.5 36.7 48.3 55.5 26.8 38.1 52.8 48.8 122.5 47.7 46.1 46.2 39.8 49.9 57.9 85.5 66.6 74.3 59.6 168.0 73.9 129.1 100.1 112.5 46.6 41.3 52.7 34.6 120.1 51.6 31.9 93.4 67.5 103.8 91.4 70.2 72.0 69.4 42.9 74.2 70.1 64.7 55.3 67.8 102.3 82.0 67.6 73.1 78.2 52.6 136.0 98.3 88.6 91.1 47.8 86.5 64.0 76.4 72.6 75.7 66.4 60.9 76.9 26.1 56.2 61.1 59.8 40.9 66.1 99.1 91.5 51.1 65.6 62.5 55.7 85.0 103.3 178.4 112.3 57.2 80.4 73.9 40.4 32.7 62.5 22.3 32.6 22.5 19.5 21.9 22.3 30.3 20.4 21.9 22.8 175.1 29.8 34.2 13.5 28.3 28.2 36.7 37.9 42.6 37.4 36.9 35.8 38.3 36.9 37.0 36.7 38.1 39.8 28.5 22.4 37.6 47.7 36.1 34.4 35.2 22.1 27.9 56.7 27.5 22.6 29.0 35.8 25.7 27.6 66.7 40.0 41.5 31.3 13.7 25.6 8.8 33.2 37.1 32.7 29.3 46.7 46.1 37.0 46.8 32.3 27.5 43.8 34.2 78.7 36.0 41.2 28.6 43.7 52.9 31.0 30.5 39.3 43.4 4.6 39.1 34.7 26.6 44.0 49.5 31.9 51.5 65.4 64.0 35.5 29.9 41.3 43.3 46.9 47.3 20.1 31.2 81.9 32.9 56.2 39.1 28.3 33.6 31.8 43.5 62.3 40.8 35.6 31.2 47.1 RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785809 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA 160000 "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear membrane" "Nucleoplasm, Vesicles" "CAB034063: AB_2176784, HPA018437: AB_2620151, HPA023960: AB_2671385, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (1.28e-2)" "unprognostic (9.30e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.23e-1)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (8.74e-2)" "unprognostic (3.08e-1)" "unprognostic (3.40e-2)" "unprognostic (2.53e-1)" 20.3 24.3 8.6 16.3 11.6 42.1 19.7 14.4 17.1 18.1 20.3 15.6 13.4 17.7 20.5 14.3 14.6 13.7 14.9 11.8 9.4 18.1 17.4 14.0 18.6 9.2 8.1 24.4 20.2 30.1 21.5 16.5 9.5 20.9 15.2 26.5 16.4 17.2 30.3 17.2 13.4 15.2 8.6 15.0 17.6 21.3 8.2 23.3 28.4 23.6 18.0 16.9 12.1 12.2 40.5 24.2 34.1 31.0 38.7 34.5 32.9 35.5 28.0 28.7 25.1 60.7 18.9 63.2 26.8 37.2 35.3 33.1 58.9 36.9 41.5 38.9 28.5 65.9 30.3 43.2 22.5 77.9 21.3 29.1 27.5 44.9 34.7 28.3 44.5 27.1 71.9 34.0 38.4 22.3 34.8 31.6 43.0 20.3 28.7 32.3 52.3 30.7 25.3 49.6 49.4 22.6 31.5 26.7 34.7 20.4 17.2 35.4 53.5 29.8 39.6 21.2 40.2 27.9 44.4 55.8 23.1 34.4 23.5 5.4 2.6 2.7 3.7 1.7 4.1 2.7 3.0 3.4 2.2 2.7 2.9 3.3 3.9 2.2 3.6 2.6 2.7 1.4 8.6 11.6 14.4 17.1 11.8 9.4 9.2 8.1 9.5 8.6 8.2 12.2 54.5 76.9 85.3 48.6 91.5 55.7 34.5 39.1 61.5 51.2 34.1 25.8 103.9 38.6 63.0 58.8 73.0 28.8 96.1 28.9 1.9 34.7 77.3 83.6 65.3 55.7 106.4 50.5 125.5 50.9 17.5 56.5 68.3 142.1 84.9 52.2 31.4 56.6 47.9 32.0 92.2 59.5 44.7 44.9 80.7 32.9 38.5 114.0 48.0 55.3 57.0 20.0 34.0 44.2 80.0 41.5 29.9 56.1 118.4 44.1 28.8 15.6 67.0 40.5 46.0 56.9 59.0 78.3 65.4 53.3 67.8 40.6 104.8 25.3 38.3 38.7 RANBP3 ENSG00000031823 "RAN binding protein 3" Q9H6Z4 19 5916139-5978142 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043375, HPA043389" Enhanced Enhanced Nucleoplasm NA NA 17000 "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA043375: AB_10959889, HPA043389: AB_10963696" "unprognostic (1.81e-1)" "unprognostic (1.18e-3)" "unprognostic (3.61e-1)" "prognostic favorable (1.22e-5)" "unprognostic (4.24e-2)" "unprognostic (1.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.08e-1)" "prognostic favorable (4.14e-4)" "unprognostic (2.27e-1)" "unprognostic (3.80e-2)" "unprognostic (2.91e-1)" "unprognostic (5.15e-2)" "prognostic favorable (8.14e-4)" "unprognostic (1.06e-2)" 25.1 40.3 30.0 24.0 30.6 21.5 24.7 30.4 33.7 30.5 25.0 43.1 22.2 35.1 10.6 26.6 29.0 17.8 35.3 30.0 30.3 24.6 24.4 25.2 26.5 33.0 34.9 28.2 29.6 20.7 32.0 16.7 31.7 32.2 12.1 19.3 25.6 22.9 36.6 29.2 27.6 19.0 30.5 30.1 32.0 44.7 31.5 26.2 25.8 21.3 17.9 36.6 27.9 31.1 73.8 50.4 42.3 47.6 31.2 31.3 30.0 45.9 43.1 52.7 56.7 64.9 25.4 69.0 50.4 35.8 33.1 44.8 38.2 44.8 32.0 71.0 62.3 37.1 38.8 77.6 33.7 54.9 52.2 30.9 30.4 33.0 37.3 24.5 38.9 37.0 68.4 63.6 30.3 30.7 91.8 26.6 77.6 31.8 64.3 67.0 40.6 63.3 34.3 56.3 46.4 52.1 41.1 42.9 41.1 24.7 32.7 41.0 40.6 44.2 32.2 78.2 68.4 65.4 72.1 59.2 55.9 68.0 55.6 14.5 23.1 29.2 23.2 23.2 24.1 17.6 22.7 23.5 23.4 24.5 19.5 25.8 26.0 17.9 24.3 22.3 32.1 24.5 30.0 30.6 30.4 33.7 30.0 30.3 33.0 34.9 31.7 30.5 31.5 31.1 14.0 25.6 26.6 9.8 18.4 12.2 20.5 27.1 9.6 16.7 12.0 10.2 16.4 18.6 19.9 7.3 25.0 29.2 18.6 16.9 43.0 28.8 59.5 14.3 12.6 19.2 13.2 8.6 9.4 20.8 29.5 17.1 17.3 15.4 17.7 14.1 9.3 10.8 25.0 23.5 11.7 20.2 32.6 14.9 16.8 73.3 16.8 16.5 21.4 8.4 31.5 21.9 25.7 13.6 17.5 22.7 11.4 24.8 21.7 18.8 20.2 21.0 21.4 20.8 19.7 13.5 15.8 86.8 40.8 10.4 11.8 35.4 20.6 19.1 15.1 23.0 RAP1GDS1 SmgGDS ENSG00000138698 "Rap1 GTPase-GDP dissociation stimulator 1" P52306 4 98261384-98443858 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.4" "Cell type enhanced" "Detected in many" "Early spermatids: 434.9;Inhibitory neurons: 176.3;Late spermatids: 245.3;Oligodendrocytes: 357.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019060 Approved Supported Cytosol NA NA 62000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA019060: AB_1856068" "unprognostic (8.12e-2)" "unprognostic (1.50e-1)" "unprognostic (2.69e-3)" "unprognostic (1.66e-1)" "unprognostic (9.11e-2)" "unprognostic (1.35e-2)" "unprognostic (1.57e-3)" "unprognostic (3.44e-1)" "unprognostic (6.31e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (4.60e-1)" "prognostic favorable (2.00e-4)" "unprognostic (7.11e-2)" "unprognostic (3.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" 15.6 12.6 49.3 18.8 54.9 14.3 17.4 56.3 56.7 11.7 25.2 16.5 10.0 12.2 11.2 18.5 9.6 11.6 9.6 48.3 54.1 16.5 21.1 14.0 23.4 59.5 62.6 10.8 19.1 10.3 16.1 13.2 67.6 10.3 18.6 65.7 12.5 15.1 5.8 14.4 14.3 22.1 51.9 18.0 11.2 22.6 64.4 32.4 17.6 5.7 24.4 19.0 12.9 72.4 50.8 30.4 37.8 32.8 47.6 56.4 14.2 86.7 48.6 51.1 40.0 22.7 66.5 61.0 26.3 65.9 24.3 27.8 47.0 80.5 68.7 60.4 17.1 37.0 35.6 29.6 93.8 64.1 25.2 65.7 47.8 45.3 69.5 42.3 67.9 61.9 25.7 51.6 128.3 27.7 104.9 31.3 13.9 43.0 19.0 41.5 22.4 20.8 51.7 40.8 55.0 32.5 36.2 81.2 48.9 20.6 18.5 41.5 67.2 52.7 36.8 23.9 51.7 16.5 30.1 51.1 43.9 47.3 69.7 32.8 17.4 10.4 23.3 24.9 24.2 23.9 24.4 23.5 27.9 17.1 12.3 19.5 2.5 37.0 28.5 60.6 41.2 14.8 49.3 54.9 56.3 56.7 48.3 54.1 59.5 62.6 67.6 51.9 64.4 72.4 17.6 16.0 12.2 88.8 34.7 13.9 10.8 11.7 22.8 48.2 17.1 12.2 11.1 14.3 14.7 16.5 50.1 6.8 45.7 9.7 23.5 17.7 434.9 7.4 16.2 15.7 20.9 19.8 146.4 20.9 16.5 11.5 16.8 11.2 15.2 19.8 13.9 18.5 23.8 15.2 176.3 13.0 12.2 33.4 27.6 245.3 9.3 24.7 17.8 89.0 32.6 16.9 34.0 110.6 357.6 23.4 14.6 10.9 30.4 16.3 14.5 20.4 7.6 77.5 0.0 12.7 17.2 16.7 36.5 26.8 16.8 4.5 34.3 19.8 18.4 15.1 RARA "NR1B1, RAR" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 221.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: AB_2683666, HPA071548: " "unprognostic (8.05e-3)" "unprognostic (1.89e-1)" "unprognostic (9.48e-3)" "prognostic favorable (2.60e-4)" "unprognostic (8.67e-3)" "unprognostic (4.87e-3)" "unprognostic (2.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.45e-1)" "unprognostic (3.54e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.29e-3)" "unprognostic (1.59e-2)" "unprognostic (5.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" 47.6 21.1 3.2 28.3 4.4 59.6 37.2 7.2 16.5 43.7 5.1 31.0 28.4 32.2 10.7 14.9 40.7 41.3 40.8 7.0 5.7 24.1 42.3 58.4 16.4 5.3 2.7 40.8 14.7 11.3 30.6 25.7 2.8 29.8 13.2 18.3 20.6 21.3 62.6 24.8 32.2 28.6 1.8 41.7 22.9 28.8 4.9 10.0 26.9 17.4 11.8 30.3 30.2 4.3 18.0 41.9 11.8 20.5 23.4 35.9 12.5 14.9 21.8 21.5 13.6 28.6 15.1 9.6 22.7 33.2 18.9 51.1 14.2 33.9 12.0 77.5 21.4 26.6 21.2 29.8 37.0 9.4 81.3 48.2 10.0 22.7 29.2 75.8 30.9 8.4 17.6 20.2 23.7 221.5 6.4 34.2 10.7 16.2 13.3 12.9 71.3 37.0 12.2 14.4 5.4 40.5 31.0 124.8 42.1 11.7 119.1 36.6 35.8 25.3 45.3 44.2 15.4 48.7 16.9 8.3 38.4 18.7 77.1 26.3 8.9 34.6 3.2 14.6 5.1 2.0 3.6 3.8 12.4 1.7 1.5 2.8 52.6 5.9 19.5 3.8 3.1 5.0 3.2 4.4 7.2 16.5 7.0 5.7 5.3 2.7 2.8 1.8 4.9 4.3 35.6 3.2 7.0 2.3 43.4 19.5 25.6 8.4 18.8 23.2 35.4 17.5 3.8 10.0 5.5 7.3 6.2 2.2 36.9 41.2 13.7 16.7 60.5 20.7 22.0 28.4 9.6 5.7 5.4 19.2 5.8 28.5 10.7 18.4 35.5 13.9 26.0 28.8 12.3 3.3 2.6 13.1 6.1 45.4 65.5 66.2 41.7 56.9 28.4 2.8 26.1 11.8 6.2 4.0 0.3 22.0 33.1 23.0 21.0 13.4 70.9 17.7 4.9 10.2 32.9 42.1 26.7 3.6 7.6 7.1 18.9 5.2 31.7 6.5 16.5 19.3 RARB "HAP, NR1B2, RRB2" ENSG00000077092 "Retinoic acid receptor beta" P10826 3 25174332-25597932 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Microphthalmia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 41.4;Excitatory neurons: 66.8;Inhibitory neurons: 92.6;Microglial cells: 29.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 13.7;HEK 293: 16.0;hTERT-RPE1: 82.3;WM-115: 36.5" "Region enriched" "Detected in all" 9 "basal ganglia: 109.2" "CAB002617, HPA004174" Enhanced Enhanced Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB002617: , HPA004174: AB_1079744" "unprognostic (2.04e-2)" "unprognostic (3.53e-2)" "unprognostic (1.93e-1)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.72e-2)" "unprognostic (1.30e-2)" "unprognostic (2.70e-2)" "unprognostic (2.43e-1)" "unprognostic (4.71e-2)" "unprognostic (1.62e-1)" "unprognostic (2.86e-1)" "prognostic favorable (3.43e-5)" "unprognostic (9.24e-3)" "unprognostic (2.28e-1)" "unprognostic (9.99e-2)" "unprognostic (6.56e-3)" 4.1 7.0 3.5 2.6 15.0 0.0 6.9 2.2 6.6 9.3 7.2 6.0 1.7 7.4 6.7 7.9 6.0 5.3 14.0 3.5 1.4 15.1 6.5 5.3 6.7 3.4 1.7 11.5 1.3 6.0 7.5 14.4 0.9 12.5 2.2 13.6 13.1 11.2 2.4 1.1 2.0 5.9 1.4 4.9 3.9 0.6 2.4 1.2 9.1 5.3 4.2 7.2 6.1 3.7 0.0 1.9 1.2 6.4 13.7 3.6 0.0 1.6 0.8 0.0 0.6 0.3 0.1 0.1 0.2 2.5 0.3 0.4 0.0 0.3 0.0 0.1 16.0 0.1 0.1 1.1 0.3 0.2 0.1 7.1 0.0 0.0 0.0 82.3 13.4 0.1 0.1 5.6 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.6 8.3 0.0 0.2 0.1 9.1 0.0 0.1 0.0 1.1 0.1 2.1 7.0 0.2 0.0 0.1 5.6 0.2 36.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 15.0 2.2 6.6 3.5 1.4 3.4 1.7 0.9 1.4 2.4 3.7 2.4 0.0 0.5 41.4 0.3 0.1 18.0 6.4 1.8 4.5 1.7 7.5 12.0 12.8 14.9 11.0 25.0 0.2 0.8 0.0 0.0 1.6 1.5 8.3 4.2 10.5 0.0 0.0 66.8 0.9 0.1 6.8 7.7 3.0 0.0 0.1 22.1 2.1 0.4 5.0 92.6 0.0 2.0 1.9 0.4 1.2 0.0 0.3 0.0 29.0 0.0 24.8 0.0 19.6 2.9 1.4 0.0 0.0 0.2 10.2 0.6 0.6 9.2 6.3 0.0 2.9 9.7 0.2 1.0 6.6 0.1 0.3 0.5 0.2 0.2 9.7 RARG "NR1B3, RARC" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.6;skin 1: 121.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 42.7;Squamous epithelial cells: 69.9;Suprabasal keratinocytes: 55.8;Urothelial cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.8" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 101.0;MCF7: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA053883: AB_2682292" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (6.11e-2)" "prognostic unfavorable (3.68e-6)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (1.08e-2)" "unprognostic (3.54e-3)" "unprognostic (7.21e-3)" "unprognostic (3.78e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (5.41e-3)" "unprognostic (1.98e-2)" "unprognostic (5.94e-3)" "unprognostic (7.41e-2)" 17.4 16.2 10.2 5.7 9.7 3.7 19.4 13.0 10.9 55.0 10.8 22.7 2.5 23.3 6.0 141.6 27.2 15.7 17.3 9.7 9.5 12.5 3.2 15.2 5.9 10.3 10.0 20.5 8.5 7.2 8.7 9.5 9.3 26.9 7.8 3.9 30.6 16.2 6.9 121.4 10.4 13.0 10.0 10.2 14.5 4.8 9.5 5.1 22.6 10.6 22.5 26.2 69.3 10.0 22.8 24.7 5.5 50.9 55.0 46.8 1.7 23.2 50.0 29.7 23.3 8.3 101.0 0.5 12.5 93.6 16.2 74.3 18.4 44.6 7.4 5.7 9.4 3.3 18.6 7.4 23.2 0.0 9.1 34.8 63.9 28.5 6.4 74.7 12.7 4.6 0.8 9.8 11.9 110.3 1.3 1.1 16.3 30.4 42.7 7.3 1.9 18.1 8.9 37.1 4.4 22.9 47.0 50.6 32.1 6.8 43.9 1.4 13.8 35.4 16.5 23.6 1.5 4.2 2.6 1.8 43.4 3.8 51.3 1.8 3.1 0.9 7.4 0.9 18.8 2.0 6.5 5.4 6.7 0.6 5.2 4.7 0.0 2.3 0.0 0.6 1.8 4.0 10.2 9.7 13.0 10.9 9.7 9.5 10.3 10.0 9.3 10.0 9.5 10.0 10.7 3.2 7.0 21.2 2.5 34.2 24.1 21.6 42.7 0.5 18.0 15.6 3.7 11.5 11.1 3.7 2.1 7.5 6.2 3.2 0.0 10.5 0.1 3.6 14.4 11.0 1.8 0.8 2.5 5.1 1.2 19.6 13.7 3.4 1.3 0.3 20.3 0.1 2.7 0.0 3.0 2.1 12.2 4.1 13.3 0.5 5.3 4.9 8.8 6.5 1.8 3.6 5.2 7.1 0.7 14.3 4.4 5.3 3.0 19.2 0.2 0.5 3.9 5.2 6.6 9.5 22.0 0.8 5.6 69.9 55.8 1.8 7.2 0.4 5.5 45.7 RASA1 "CM-AVM, GAP, p120, p120GAP, p120RASGAP, RASA" ENSG00000145715 "RAS p21 protein activator 1" P20936 5 87267883-87391931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 96.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 196.7;Excitatory neurons: 192.1;Inhibitory neurons: 234.7;Oligodendrocyte precursor cells: 165.4;Oligodendrocytes: 220.1;Syncytiotrophoblasts: 487.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007789, HPA036393, HPA064556" Enhanced NA NA 12000 "Cluster 15: NK-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB007789: AB_598183, HPA036393: AB_2675097, HPA064556: AB_2685285" "unprognostic (1.57e-1)" "unprognostic (7.63e-2)" "unprognostic (1.88e-3)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "unprognostic (1.38e-2)" "unprognostic (6.88e-2)" "unprognostic (8.38e-3)" "unprognostic (2.23e-1)" "unprognostic (1.07e-2)" "unprognostic (4.12e-3)" "unprognostic (1.03e-1)" "unprognostic (3.98e-2)" "unprognostic (1.59e-2)" "unprognostic (5.39e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-3)" 16.4 14.6 12.3 15.1 14.5 13.9 18.6 21.8 15.6 17.4 9.9 14.7 12.4 21.1 20.3 16.7 15.6 16.2 12.9 15.6 12.5 15.2 12.4 15.0 19.7 9.6 13.2 25.8 13.3 24.8 11.5 96.8 12.7 14.1 17.5 34.6 15.4 15.3 9.5 18.6 13.8 15.5 9.5 19.1 13.7 26.7 11.2 25.3 24.4 15.7 18.1 17.0 12.6 15.5 31.7 16.1 31.0 20.6 26.5 37.3 23.5 47.5 32.0 30.3 49.2 13.0 82.9 20.7 11.1 54.9 33.8 15.4 14.0 40.7 95.0 19.9 11.1 15.6 15.3 13.7 25.3 12.7 18.6 21.0 27.1 84.1 48.5 51.5 42.5 11.8 8.8 44.4 109.3 20.5 14.7 21.8 16.6 6.9 29.5 17.5 66.4 30.0 29.0 27.7 18.2 20.1 18.4 24.4 29.6 29.4 21.7 20.4 61.3 38.3 17.6 21.1 60.0 16.0 15.6 20.5 55.1 25.3 27.3 2.1 0.6 0.9 0.9 1.2 1.6 0.7 1.2 1.0 0.5 1.1 1.0 0.9 0.8 3.9 1.2 0.6 1.8 0.5 12.3 14.5 21.8 15.6 15.6 12.5 9.6 13.2 12.7 9.5 11.2 15.5 18.6 12.8 15.8 86.5 13.9 14.9 6.7 12.5 16.5 35.7 18.5 11.4 6.4 7.2 15.2 16.5 29.2 196.7 11.5 12.5 5.9 10.4 7.7 15.7 18.3 20.2 16.2 12.8 192.1 7.8 53.7 16.2 18.3 16.5 8.8 22.1 18.2 11.7 47.8 32.0 234.7 12.9 12.2 27.1 9.5 4.8 14.0 21.2 14.2 128.4 13.6 12.6 7.2 165.4 220.1 23.4 14.8 13.5 15.9 11.9 10.7 11.2 19.1 18.6 0.0 21.6 15.0 33.9 20.0 17.7 17.5 487.5 17.7 16.4 13.8 11.2 RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303744-48599436 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 187.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Supported Nucleoplasm NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008" "unprognostic (4.24e-3)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-2)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "unprognostic (7.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.92e-4)" "unprognostic (4.06e-2)" "unprognostic (9.40e-2)" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (9.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" 20.7 18.7 8.9 22.8 9.7 19.3 17.8 12.0 13.0 18.8 10.9 15.1 14.6 15.7 21.2 21.9 13.1 17.3 17.8 8.5 10.9 18.4 14.5 18.1 30.7 13.9 10.3 11.5 9.2 20.5 6.5 24.9 13.4 15.1 17.1 12.5 16.9 15.9 19.0 23.6 15.6 18.3 11.6 24.8 16.3 12.9 9.3 34.2 22.4 21.2 30.1 19.8 10.6 15.1 29.1 15.8 40.9 44.2 19.8 22.8 18.5 56.6 45.9 57.4 48.3 13.4 49.8 37.3 12.8 37.4 31.7 39.6 53.7 44.8 86.6 53.0 20.8 68.5 29.4 22.7 21.1 59.5 62.0 12.9 27.0 37.3 47.1 47.8 40.1 90.1 23.4 29.6 66.4 13.7 187.2 29.8 20.0 65.6 17.3 79.8 41.1 43.0 59.6 27.6 2.0 41.8 55.1 27.3 46.2 36.2 29.8 76.3 32.1 35.3 23.3 43.7 51.2 13.1 3.9 0.4 18.8 36.7 48.9 23.8 14.9 8.8 6.9 19.9 5.6 30.2 5.7 6.9 15.2 29.4 4.8 5.6 20.6 5.9 20.9 16.9 7.4 7.1 8.9 9.7 12.0 13.0 8.5 10.9 13.9 10.3 13.4 11.6 9.3 15.1 59.2 3.2 19.6 75.4 97.3 28.4 23.3 27.6 63.2 17.3 26.9 21.0 18.3 14.3 19.2 31.3 29.2 7.1 50.1 17.8 15.6 19.3 28.1 40.1 36.2 46.4 17.5 50.7 99.5 11.9 9.6 22.2 29.0 40.4 12.0 25.9 35.7 17.3 77.4 18.5 98.9 20.0 8.2 105.3 198.9 13.9 26.1 104.2 26.6 152.7 93.7 20.4 22.6 101.0 98.3 17.4 10.7 28.6 69.9 24.0 15.7 23.6 25.3 19.6 19.7 28.5 32.3 33.0 21.3 72.1 38.2 4.4 38.3 21.2 16.6 18.0 RBBP4 "lin-53, NURF55, RbAp48" ENSG00000162521 "RB binding protein 4, chromatin remodeling factor" Q09028 1 32651142-32686211 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006264, HPA060710, HPA060724" Supported Enhanced Nucleoplasm NA NA 150000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB006264: AB_425651, HPA060710: AB_2684347, HPA060724: AB_2684350" "unprognostic (1.18e-3)" "unprognostic (1.79e-3)" "unprognostic (2.96e-3)" "unprognostic (1.82e-2)" "prognostic favorable (9.23e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (1.89e-6)" "unprognostic (1.24e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (1.57e-2)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" "unprognostic (1.36e-3)" "unprognostic (3.05e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.88e-2)" 32.0 38.8 19.9 33.5 21.8 34.8 38.5 24.7 21.1 40.3 21.5 33.3 27.0 42.4 35.1 32.1 45.5 25.3 31.7 18.7 21.8 31.9 30.6 28.8 62.9 21.4 21.1 46.9 38.5 34.0 31.1 34.6 23.0 30.0 45.9 56.2 38.3 30.7 42.9 33.2 35.7 42.1 22.9 32.7 37.1 75.5 21.3 58.0 45.8 21.1 91.5 35.2 31.2 30.1 68.8 59.1 166.2 120.1 49.9 47.4 66.7 55.3 44.9 103.0 99.7 85.5 135.6 206.9 54.8 61.4 62.7 42.9 184.7 53.6 110.0 80.9 88.3 194.3 112.0 111.9 72.3 183.9 79.9 52.2 66.8 78.1 50.3 83.6 77.2 139.8 138.0 142.1 89.0 48.0 239.4 57.6 185.4 67.0 67.8 228.3 173.8 181.0 72.4 143.4 156.7 94.7 122.1 41.9 83.8 161.3 71.9 83.3 64.3 63.8 61.6 80.4 70.2 113.4 128.0 229.5 75.2 146.9 99.3 79.1 99.9 68.5 74.4 99.8 77.4 79.6 69.8 75.2 115.0 60.1 61.2 67.3 24.8 87.7 95.4 95.7 77.9 151.8 19.9 21.8 24.7 21.1 18.7 21.8 21.4 21.1 23.0 22.9 21.3 30.1 61.6 41.7 53.7 32.3 115.8 71.5 68.3 76.8 120.1 106.1 105.2 57.3 22.2 77.2 59.1 73.5 143.9 129.2 132.0 55.4 84.1 84.7 26.3 51.2 89.0 65.7 97.1 201.4 38.0 58.3 87.6 81.3 70.3 71.6 49.4 93.3 64.6 76.5 80.6 106.0 41.5 83.9 79.3 78.8 74.3 17.5 79.6 80.8 49.8 22.5 90.7 77.4 91.6 44.2 49.7 76.1 42.1 88.4 201.8 59.5 44.3 65.9 50.5 109.2 98.6 47.6 76.9 154.2 88.8 132.5 77.4 85.5 95.4 79.5 86.9 58.7 RBL1 "cp107, p107, PRB1" ENSG00000080839 "RB transcriptional corepressor like 1" P28749 20 36996349-37095997 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.3;Inhibitory neurons: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054962, HPA056525" Enhanced Enhanced Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA054962: AB_2682652, HPA056525: AB_2683165" "unprognostic (1.97e-1)" "unprognostic (2.47e-2)" "unprognostic (1.30e-2)" "unprognostic (3.70e-3)" "unprognostic (2.13e-1)" "unprognostic (1.51e-1)" "unprognostic (6.25e-5)" "unprognostic (6.91e-2)" "unprognostic (7.19e-3)" "unprognostic (1.20e-1)" "unprognostic (4.49e-3)" "unprognostic (3.23e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (3.15e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-2)" "unprognostic (1.26e-1)" 2.0 1.6 1.2 4.8 2.6 14.5 2.8 8.3 1.8 2.3 0.7 2.8 2.4 2.8 1.3 2.9 1.9 2.0 1.8 1.0 1.9 1.6 1.4 2.2 7.3 2.0 1.9 4.4 2.4 2.6 1.1 3.4 2.2 2.0 3.5 4.0 1.5 1.4 6.9 3.1 2.5 2.8 1.4 3.4 2.7 3.1 2.0 8.8 2.7 7.9 6.7 2.0 2.2 3.4 24.8 15.8 19.4 13.1 4.9 6.4 12.4 28.2 12.6 23.9 24.6 16.8 13.5 27.5 7.9 11.8 14.0 23.8 17.5 18.2 39.7 9.7 9.4 27.2 18.1 14.3 3.0 35.3 18.2 3.0 2.5 31.6 11.1 4.0 13.6 17.9 20.1 25.8 13.7 10.5 33.1 11.7 5.7 12.5 15.3 21.3 57.7 20.9 5.5 12.2 4.6 11.5 30.8 17.6 8.2 6.2 11.3 25.3 9.1 42.0 15.9 38.9 24.8 8.6 16.4 27.7 30.2 24.4 21.1 0.9 0.7 1.4 2.7 0.8 2.3 3.0 3.0 2.5 1.3 2.1 3.2 2.7 0.3 2.2 1.2 3.0 4.5 0.9 1.2 2.6 8.3 1.8 1.0 1.9 2.0 1.9 2.2 1.4 2.0 3.4 3.5 6.4 11.0 10.4 8.7 2.4 1.5 1.7 4.0 5.9 2.5 1.7 2.9 1.5 6.1 0.0 2.1 5.9 6.5 1.8 0.0 1.8 1.5 2.2 4.3 3.3 1.2 23.3 14.7 1.1 5.1 4.6 2.6 2.9 8.8 9.0 2.2 1.4 4.5 3.3 22.8 1.9 0.0 3.0 3.2 0.6 2.1 6.8 1.8 6.5 4.7 3.1 7.2 19.6 18.5 0.9 3.6 3.0 14.1 0.8 1.0 0.7 0.9 12.2 6.6 8.5 4.1 17.5 8.7 5.3 1.3 3.8 11.7 6.4 3.5 0.9 RBL2 "p130, Rb2" ENSG00000103479 "RB transcriptional corepressor like 2" Q08999 16 53433977-53491648 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 468.3;Late spermatids: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016547, HPA019703" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Cytosol" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli rim, Mitotic chromosome" Cytosol "CAB016547: AB_785011, HPA019703: AB_1856106" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (4.00e-2)" "unprognostic (1.26e-1)" "unprognostic (6.88e-2)" "unprognostic (6.43e-2)" "unprognostic (5.03e-2)" "unprognostic (2.46e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-1)" "unprognostic (4.70e-1)" "unprognostic (8.12e-2)" "prognostic favorable (3.57e-5)" "unprognostic (9.57e-3)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (7.51e-2)" 32.5 25.4 11.1 32.3 13.6 19.1 31.7 12.5 10.4 33.5 14.8 26.6 23.3 32.2 20.2 25.0 31.8 27.7 25.6 8.7 10.5 39.2 59.5 38.9 49.7 12.3 12.0 37.8 39.0 62.7 17.7 19.3 13.0 42.9 29.3 23.1 34.2 39.9 32.4 26.3 26.1 30.7 11.7 41.0 32.6 48.4 11.4 66.6 40.2 37.7 51.2 30.9 28.9 16.9 25.9 18.1 20.7 20.6 61.2 57.9 9.4 17.8 26.4 23.1 7.9 10.1 30.9 39.0 28.4 32.8 22.3 29.6 17.9 30.1 36.0 12.5 22.4 15.9 14.7 22.0 27.3 23.4 49.0 35.6 34.0 15.3 22.4 43.0 36.3 39.6 12.7 23.2 26.6 7.1 48.6 22.0 7.8 30.8 15.0 33.6 41.8 46.1 25.4 25.3 16.9 14.3 42.2 17.2 19.1 16.8 22.7 30.0 28.3 27.5 14.3 24.1 13.7 35.7 22.9 42.4 34.4 28.2 19.0 53.9 22.5 56.5 53.4 16.2 60.5 22.5 59.7 62.8 21.7 22.0 85.5 75.3 41.8 74.4 28.8 13.1 48.2 76.2 11.1 13.6 12.5 10.4 8.7 10.5 12.3 12.0 13.0 11.7 11.4 16.9 37.9 41.7 101.1 51.2 49.5 23.1 30.1 15.3 40.9 27.8 27.0 15.5 13.5 45.8 32.5 27.6 20.9 6.0 77.0 26.3 17.6 13.4 468.3 38.9 25.8 31.4 19.8 26.5 55.1 10.2 13.0 35.8 24.5 45.9 55.1 27.9 40.7 46.1 11.2 35.3 54.1 30.0 34.6 43.6 23.7 209.1 42.0 35.4 10.6 58.1 44.9 38.3 79.3 63.3 85.7 10.8 19.0 42.9 48.7 31.4 29.2 25.3 38.3 22.5 39.5 36.2 26.1 161.4 61.3 33.7 27.6 4.1 118.9 25.2 21.7 35.6 RBM10 "DXS8237E, GPATC9, GPATCH9, KIAA0122, S1-1, ZRANB5" ENSG00000182872 "RNA binding motif protein 10" P98175 X 47145221-47186813 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034972, HPA057372" Approved Enhanced "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" "HPA034972: AB_10602919, HPA057372: AB_2683421" "unprognostic (9.07e-2)" "prognostic favorable (6.71e-4)" "unprognostic (7.83e-2)" "unprognostic (1.61e-2)" "unprognostic (1.86e-1)" "unprognostic (3.04e-2)" "unprognostic (4.47e-3)" "unprognostic (8.11e-2)" "unprognostic (9.86e-3)" "unprognostic (1.76e-1)" "prognostic favorable (2.86e-6)" "unprognostic (1.18e-1)" "unprognostic (6.23e-3)" "unprognostic (3.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.40e-2)" "unprognostic (1.20e-3)" 23.7 31.1 28.5 19.9 28.8 32.5 23.9 32.6 36.4 33.3 26.6 28.8 18.1 29.5 12.4 34.2 31.5 12.1 30.8 28.5 28.4 30.0 32.2 23.9 25.1 28.2 27.9 40.6 32.2 15.9 38.0 17.3 28.3 33.8 11.3 14.8 23.6 15.6 26.5 27.1 27.8 12.5 26.6 33.9 26.4 12.8 29.3 23.6 33.1 12.4 15.9 28.3 29.9 31.9 50.1 52.5 48.9 58.8 25.7 21.0 57.3 36.8 21.4 37.2 35.8 46.4 39.8 60.1 22.0 25.6 47.5 47.7 64.9 46.1 20.4 61.6 59.0 45.1 65.1 48.8 37.5 46.0 52.1 27.7 22.0 61.2 49.8 26.5 40.4 56.5 38.3 47.0 23.0 74.9 84.8 78.2 81.9 37.1 58.0 74.0 41.0 62.2 27.7 42.9 58.6 44.5 56.0 41.6 35.6 29.3 50.9 45.7 35.8 43.7 54.9 47.8 39.5 48.4 42.9 49.5 38.8 32.8 62.3 13.5 8.1 11.4 12.7 10.7 12.0 11.2 10.2 10.8 9.2 11.1 10.0 9.7 7.5 9.9 15.8 10.7 12.7 9.3 28.5 28.8 32.6 36.4 28.5 28.4 28.2 27.9 28.3 26.6 29.3 31.9 17.4 41.7 36.9 22.5 21.6 11.1 22.4 15.0 22.8 26.7 16.5 16.8 36.6 21.5 28.8 9.2 14.6 34.2 21.3 32.2 11.7 20.5 1.3 23.6 20.1 19.6 35.8 14.9 14.8 17.7 28.5 20.2 31.6 31.5 24.1 29.1 16.8 23.3 19.7 21.9 15.4 31.5 10.2 14.2 10.0 2.7 18.0 15.4 16.0 8.4 19.9 14.7 20.6 15.1 18.1 19.8 20.8 25.6 22.5 18.7 23.1 14.3 28.8 27.0 0.0 21.4 21.8 10.7 8.7 23.4 10.5 46.1 23.8 19.7 34.2 18.1 RBM15 "OTT, OTT1" ENSG00000162775 "RNA binding motif protein 15" Q96T37 1 110338506-110346681 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015201, HPA019824, HPA049642" Supported Enhanced Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB015201: , HPA019824: AB_1856113, HPA049642: AB_2680839" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (9.39e-2)" "unprognostic (7.57e-3)" "unprognostic (2.43e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (1.13e-1)" "unprognostic (1.84e-2)" "unprognostic (4.91e-2)" "unprognostic (9.67e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.37e-4)" "prognostic favorable (7.97e-4)" "unprognostic (2.88e-1)" "unprognostic (2.46e-2)" "unprognostic (2.12e-1)" 4.7 4.0 3.3 7.0 4.0 44.7 4.2 10.9 4.1 3.2 4.5 4.3 5.3 3.4 3.4 3.2 3.8 4.2 4.6 4.5 2.5 3.2 7.2 4.2 11.3 3.1 3.0 5.9 4.3 3.7 1.6 5.0 3.3 3.6 3.8 4.9 4.6 2.6 7.0 2.9 4.8 3.6 2.7 7.2 5.4 8.6 3.4 8.6 4.6 6.6 9.6 4.5 2.2 5.6 11.8 12.7 11.2 11.6 7.0 7.2 17.6 6.2 8.1 9.5 12.4 15.7 10.6 22.4 9.7 7.0 7.8 16.4 17.6 15.5 13.9 23.4 16.3 18.1 21.0 11.4 9.6 19.9 18.4 6.6 10.5 13.2 12.3 5.0 10.2 16.6 26.1 38.0 9.6 12.1 18.0 15.4 24.0 10.4 7.1 21.1 17.0 15.3 7.8 11.8 13.4 6.8 13.5 16.7 13.1 11.9 11.6 23.5 7.2 9.1 16.2 9.9 11.4 28.8 15.9 48.0 13.6 19.7 11.4 6.3 3.9 5.6 3.7 3.4 5.3 6.1 4.2 3.3 2.8 5.1 3.5 4.3 5.4 3.1 3.9 2.7 4.5 3.3 3.3 4.0 10.9 4.1 4.5 2.5 3.1 3.0 3.3 2.7 3.4 5.6 9.1 6.4 3.7 21.5 18.3 33.1 9.3 7.3 6.2 5.7 10.8 5.0 12.3 5.7 4.8 3.7 14.6 8.7 12.8 9.1 0.0 4.1 9.6 15.9 14.5 8.4 9.6 10.7 30.0 3.5 7.9 8.1 10.2 18.8 28.6 10.6 11.0 18.5 6.5 0.0 26.2 8.4 0.0 6.8 11.4 6.7 4.1 7.7 8.8 39.4 6.1 3.9 7.2 29.1 31.2 4.3 3.9 5.3 15.5 9.6 8.8 4.5 10.6 7.3 0.0 11.2 12.4 30.6 13.9 9.4 33.8 4.7 14.3 6.5 9.9 8.6 RBM6 "3G2, DEF-3, DEF3, g16, NY-LU-12" ENSG00000004534 "RNA binding motif protein 6" P78332 3 49940007-50100045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026272, HPA027164" Enhanced Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 72: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Cytoplasmic bodies" "HPA026272: AB_1847592, HPA027164: AB_1847593" "unprognostic (3.81e-3)" "unprognostic (2.13e-1)" "unprognostic (3.52e-2)" "unprognostic (2.40e-2)" "unprognostic (4.53e-2)" "unprognostic (2.88e-2)" "unprognostic (1.40e-2)" "unprognostic (7.97e-3)" "unprognostic (8.84e-3)" "unprognostic (5.09e-2)" "prognostic favorable (1.41e-4)" "unprognostic (4.31e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (7.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.45e-1)" "prognostic favorable (5.13e-5)" 65.2 75.5 51.4 43.7 50.5 45.8 58.3 56.9 96.4 108.2 53.0 81.5 43.4 70.0 34.5 51.7 81.7 27.6 74.3 51.0 54.8 74.3 78.1 64.7 59.8 53.6 51.0 96.2 89.7 36.7 72.8 30.3 50.0 98.2 39.5 64.3 50.3 36.0 44.0 54.3 78.0 42.2 48.1 103.5 69.3 66.1 53.1 48.6 74.9 25.7 50.1 67.2 68.5 51.7 28.6 18.0 73.0 48.1 70.8 38.4 25.9 47.8 41.0 40.8 42.7 31.0 31.4 147.2 27.0 47.0 41.1 23.6 61.2 40.9 51.3 57.3 23.2 68.6 46.1 41.3 40.0 71.3 69.4 36.0 50.5 45.7 50.9 76.4 52.2 37.0 57.0 36.0 39.3 26.9 66.8 106.0 57.9 34.7 32.0 26.1 31.0 38.0 40.4 57.0 28.8 51.6 43.7 31.0 30.9 62.9 25.3 55.7 48.8 41.2 48.0 33.3 48.6 49.7 123.7 84.9 23.7 58.6 40.6 16.4 8.5 5.2 13.3 4.6 11.2 12.3 9.3 8.2 8.8 11.5 9.3 10.2 5.6 7.2 8.8 9.6 7.0 6.1 51.4 50.5 56.9 96.4 51.0 54.8 53.6 51.0 50.0 48.1 53.1 51.7 76.0 57.7 75.2 172.4 87.4 54.0 43.0 34.2 67.7 120.1 43.5 33.8 35.7 40.0 45.9 62.5 102.2 38.2 91.9 46.4 11.7 33.4 31.9 51.2 69.5 57.2 47.3 51.9 195.6 28.0 33.0 53.9 64.7 46.3 43.0 93.0 45.7 36.0 27.8 92.5 216.8 44.5 36.7 56.1 82.2 25.2 65.6 50.1 60.5 161.1 66.1 43.4 62.8 154.3 177.9 34.3 32.4 60.5 106.9 51.2 60.9 17.7 49.1 145.7 46.0 55.6 63.7 135.3 56.7 46.7 45.3 36.3 66.4 66.3 39.5 35.2 RBMX "hnRNP-G, HNRNPG, RNMX" ENSG00000147274 "RNA binding motif protein X-linked" P38159 X 136848004-136880764 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Cancer-related genes, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057707 Supported Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA057707: AB_2683508" "unprognostic (1.53e-1)" "unprognostic (1.52e-3)" "unprognostic (2.12e-3)" "unprognostic (1.14e-2)" "unprognostic (2.62e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.16e-6)" "unprognostic (5.59e-2)" "unprognostic (1.05e-2)" "unprognostic (1.68e-2)" "unprognostic (4.87e-2)" "unprognostic (2.32e-2)" "unprognostic (2.94e-2)" "unprognostic (1.57e-1)" "unprognostic (7.65e-2)" "unprognostic (6.27e-2)" "unprognostic (4.64e-3)" 81.0 57.0 35.7 80.8 39.3 172.5 119.7 40.5 39.7 108.8 36.9 82.9 77.8 142.0 85.9 64.5 116.5 68.2 72.2 33.9 36.2 77.7 66.5 71.8 117.8 40.7 36.4 242.9 86.8 76.6 48.9 80.4 40.8 83.9 101.6 82.0 68.5 82.1 126.2 69.6 75.5 118.2 38.8 89.1 71.8 34.8 35.1 210.8 92.5 103.9 145.6 89.1 77.9 51.9 235.0 250.2 448.6 201.0 109.6 184.3 261.2 227.7 246.3 308.4 324.6 268.8 228.3 422.9 229.2 163.9 193.3 152.9 481.9 238.3 353.6 184.2 226.8 324.6 240.9 289.9 95.9 358.0 285.6 152.5 113.1 240.6 333.6 236.3 252.7 392.0 296.6 210.3 254.4 297.9 526.3 240.5 285.7 248.1 207.0 430.9 300.2 262.0 229.6 275.2 260.8 281.7 181.9 162.4 213.8 263.6 186.8 237.7 161.7 173.5 188.0 121.7 294.8 149.2 214.9 444.3 123.9 256.7 242.6 131.6 158.5 90.6 142.1 192.8 199.7 194.5 184.8 170.4 175.6 187.4 231.9 192.5 25.3 173.9 178.9 106.4 203.9 302.6 35.7 39.3 40.5 39.7 33.9 36.2 40.7 36.4 40.8 38.8 35.1 51.9 112.1 112.2 139.0 55.2 223.0 151.9 209.0 151.6 128.1 112.4 229.8 208.0 100.5 153.0 167.3 88.3 95.9 187.2 200.3 80.1 154.6 157.2 10.9 83.5 147.4 130.5 202.9 195.7 33.2 148.8 269.4 156.6 75.4 84.3 268.8 212.7 204.5 119.3 117.0 92.5 41.2 170.9 81.4 223.2 112.2 10.5 171.8 109.0 96.0 27.2 176.9 99.4 157.6 57.3 56.5 108.0 99.1 133.2 124.0 108.2 140.0 120.3 123.3 137.9 92.1 159.7 161.6 33.8 81.2 94.6 122.3 111.5 195.5 135.0 216.4 157.4 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" O94761 8 144511288-144517845 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;testis: 22.4" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.5;Spermatogonia: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB017800: , HPA025821: AB_1856168" "unprognostic (5.92e-2)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (9.17e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.12e-2)" "unprognostic (4.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" 1.7 1.8 3.0 5.8 3.7 25.4 2.0 7.7 7.0 2.9 0.1 4.7 6.0 2.5 0.4 13.3 2.1 2.1 1.8 2.6 1.6 2.5 2.7 2.3 6.8 6.9 2.3 2.7 3.1 0.7 3.1 2.5 7.4 8.6 1.6 1.5 5.8 0.8 2.5 10.1 5.2 1.0 1.7 6.5 3.2 22.4 4.1 7.4 3.4 0.5 2.5 2.5 3.1 3.6 33.7 58.8 27.0 57.1 1.6 2.6 47.1 33.2 5.9 24.2 20.2 58.4 48.4 22.8 21.5 5.6 14.2 40.1 18.0 14.2 6.6 40.3 68.6 82.4 118.5 44.3 0.5 21.2 65.7 3.3 2.1 27.1 5.5 3.4 6.8 45.4 83.3 28.9 8.5 104.1 77.3 56.9 18.8 27.8 69.5 80.0 21.2 37.9 6.7 35.8 52.9 32.0 45.2 37.3 12.1 7.4 45.5 45.7 9.2 38.9 117.4 47.3 62.6 16.0 18.1 39.3 22.4 64.6 39.9 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.7 7.7 7.0 2.6 1.6 6.9 2.3 7.4 1.7 4.1 3.6 0.7 0.0 0.0 2.0 2.2 1.5 0.7 0.9 1.2 2.7 3.7 2.7 1.8 1.5 0.5 0.0 4.2 3.9 1.0 5.9 0.0 0.5 3.9 2.1 0.9 0.7 0.0 6.1 2.0 0.4 8.1 1.8 4.6 2.0 0.0 8.8 0.0 0.7 3.6 0.0 1.6 4.1 0.0 0.6 1.1 7.4 1.2 1.0 0.0 0.0 0.3 0.3 1.0 0.0 0.8 0.3 0.2 1.5 9.1 0.7 0.7 0.5 0.7 1.7 0.0 1.4 1.2 23.5 20.6 6.6 1.0 1.5 1.2 0.5 7.0 0.7 REL "c-Rel, I-Rel" ENSG00000162924 "REL proto-oncogene, NF-kB subunit" Q04864 2 60881521-60931612 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.4" "Cell type enhanced" "Detected in all" "Langerhans cells: 2061.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 61.2;U-698: 109.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004404 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "CAB004404: AB_670194" "unprognostic (2.77e-1)" "unprognostic (2.05e-2)" "unprognostic (8.26e-2)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (4.41e-2)" "unprognostic (1.11e-1)" "unprognostic (7.15e-2)" "unprognostic (2.15e-1)" "unprognostic (5.87e-2)" "unprognostic (4.38e-2)" "unprognostic (4.37e-1)" "unprognostic (2.82e-2)" "unprognostic (2.91e-2)" "unprognostic (3.53e-1)" "unprognostic (3.85e-1)" "unprognostic (3.66e-2)" 4.8 4.5 2.2 14.1 1.8 37.4 5.5 8.6 4.2 4.6 0.4 4.6 4.7 5.7 2.7 6.0 3.2 8.2 2.2 2.1 2.9 3.4 7.3 6.7 15.8 3.0 1.7 5.0 5.0 6.2 1.9 5.5 2.3 4.1 4.9 9.8 4.6 2.7 2.4 8.3 5.2 3.5 0.5 11.1 5.8 3.5 2.4 9.2 4.1 2.5 16.3 13.1 3.3 3.4 7.2 3.8 3.4 4.5 2.7 2.6 7.3 2.5 3.2 1.8 2.1 3.2 6.0 61.2 6.4 2.2 4.6 7.7 5.3 3.9 4.0 7.0 5.0 6.3 6.5 3.5 1.5 13.3 7.1 2.3 10.1 4.6 7.0 3.0 4.8 6.6 7.6 4.3 1.7 4.0 9.1 5.6 4.2 5.0 1.8 12.0 8.8 2.7 2.8 24.5 3.3 3.5 6.4 7.9 2.3 5.0 4.6 5.5 5.6 5.0 6.0 3.5 3.8 5.4 2.8 109.7 3.0 10.9 2.7 3.4 4.1 2.6 2.8 4.5 2.0 5.9 1.5 2.2 3.5 7.9 1.0 2.1 5.0 2.9 5.7 3.1 1.9 2.3 2.2 1.8 8.6 4.2 2.1 2.9 3.0 1.7 2.3 0.5 2.4 3.4 67.5 320.5 325.8 8.1 430.2 517.6 123.3 69.4 194.6 82.0 95.3 58.5 5.0 48.6 165.0 51.5 85.5 29.0 469.7 59.0 3.9 31.7 4.2 150.5 79.5 103.5 42.5 37.0 16.3 29.4 58.5 97.3 96.4 300.1 412.1 82.4 30.0 19.1 51.7 58.9 16.7 49.1 46.8 141.5 2061.4 3.4 15.5 463.9 135.2 42.2 451.1 21.3 145.2 8.5 9.2 35.1 46.6 23.7 119.5 99.7 34.3 7.7 153.1 56.2 13.1 65.9 73.9 51.5 38.4 158.0 463.1 77.6 303.7 21.3 50.1 260.6 RELA "NFKB3, p65" ENSG00000173039 "RELA proto-oncogene, NF-kB subunit" Q04206 11 65653597-65663090 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004264, CAB005030, HPA063461" Supported Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB004264: AB_628017, CAB005030: AB_562171, HPA063461: AB_2685016" "unprognostic (9.17e-2)" "unprognostic (1.79e-1)" "unprognostic (2.04e-1)" "unprognostic (3.22e-1)" "unprognostic (7.67e-2)" "unprognostic (5.39e-2)" "prognostic unfavorable (9.18e-4)" "unprognostic (1.30e-3)" "unprognostic (1.69e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (5.66e-4)" "unprognostic (2.78e-1)" "unprognostic (1.46e-1)" "unprognostic (9.81e-2)" "unprognostic (2.53e-1)" 67.3 42.8 27.4 38.5 29.9 79.7 63.1 28.7 35.0 61.7 26.9 63.3 31.3 61.0 23.0 60.8 62.3 34.7 49.4 27.3 29.6 50.0 66.6 70.3 39.7 35.5 30.0 65.3 49.0 25.9 32.3 27.8 31.8 55.6 23.8 9.8 54.4 35.4 74.9 66.1 49.1 39.8 29.1 59.7 56.8 24.1 31.4 30.3 45.0 26.9 36.7 60.3 59.4 33.4 66.9 68.4 31.4 45.2 49.1 49.6 32.2 52.9 65.6 62.3 49.9 33.0 71.1 53.0 85.5 75.4 72.0 63.9 36.8 66.6 35.5 62.1 53.2 57.5 50.1 47.5 56.7 43.8 78.8 55.4 65.3 70.4 79.2 58.9 76.6 43.7 56.6 61.4 48.5 90.3 74.1 38.5 20.9 43.6 64.6 61.5 29.6 80.6 50.7 60.9 26.6 59.5 47.1 72.7 72.4 22.2 82.3 29.4 100.3 65.8 55.3 103.3 50.9 86.0 80.5 53.6 71.7 30.8 65.4 12.5 14.0 18.6 22.7 17.1 25.5 17.3 19.8 22.4 15.4 14.0 18.4 20.0 21.2 25.2 15.4 15.3 21.4 16.5 27.4 29.9 28.7 35.0 27.3 29.6 35.5 30.0 31.8 29.1 31.4 33.4 43.2 32.1 25.5 9.1 33.9 47.3 54.4 41.3 33.0 9.4 31.6 27.9 23.1 17.2 30.9 11.0 8.4 24.0 40.7 30.9 29.4 41.4 5.1 32.8 25.7 43.9 19.7 19.0 5.5 45.1 24.8 30.1 33.1 50.0 44.3 26.2 32.9 20.3 24.3 15.2 5.9 25.0 32.6 24.9 40.4 7.7 28.9 28.0 32.0 10.3 35.2 14.5 28.8 7.5 13.8 65.4 20.8 26.4 30.7 66.8 22.2 17.4 23.4 9.5 13.1 30.5 34.7 14.3 20.3 29.2 43.2 43.6 37.9 21.0 21.6 75.1 RELB REL-B ENSG00000104856 "RELB proto-oncogene, NF-kB subunit" Q01201 19 45001449-45038198 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 108.5;monocytes: 112.5;Plasma cells: 108.8;Prostatic glandular cells: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 61.9;HDLM-2: 79.5;U-698: 67.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB007753, HPA040506" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB007753: AB_562340, HPA040506: AB_2677011" "prognostic favorable (1.55e-4)" "unprognostic (1.20e-1)" "unprognostic (7.13e-2)" "unprognostic (5.52e-2)" "unprognostic (1.12e-2)" "unprognostic (3.41e-2)" "unprognostic (1.71e-2)" "unprognostic (4.30e-2)" "unprognostic (5.81e-3)" "unprognostic (1.02e-3)" "unprognostic (6.01e-2)" "unprognostic (6.48e-2)" "prognostic unfavorable (2.99e-6)" "unprognostic (2.68e-2)" "unprognostic (4.69e-2)" "unprognostic (2.09e-1)" "unprognostic (2.20e-2)" 17.2 13.1 3.5 18.7 2.9 40.1 12.6 2.9 4.4 9.1 3.1 13.3 10.8 14.1 0.8 8.7 9.2 7.4 12.7 3.1 3.4 21.3 13.0 23.0 19.2 4.9 3.5 6.4 16.5 2.1 4.0 4.8 4.1 15.3 3.9 0.2 12.1 5.2 14.0 16.5 17.7 4.9 3.6 29.1 12.0 4.3 4.6 9.2 10.0 1.4 15.6 13.8 8.1 4.1 22.2 13.0 1.3 5.7 2.8 9.1 4.5 3.9 27.5 5.9 9.6 4.5 23.6 61.9 11.0 6.4 20.8 9.8 0.5 9.0 5.1 79.5 2.0 2.2 0.8 2.5 23.8 4.9 35.3 15.0 3.7 12.3 14.4 5.4 3.9 1.7 0.5 39.2 2.1 5.3 1.1 14.9 2.0 6.3 2.4 4.8 3.2 7.7 10.0 33.7 0.1 2.0 4.1 11.4 11.6 1.4 4.0 11.8 12.6 14.4 7.1 5.3 14.4 49.0 31.2 67.0 15.6 1.7 8.1 0.0 5.1 2.5 1.4 3.4 2.0 9.2 2.2 1.9 3.8 8.0 1.7 0.8 15.2 2.1 2.8 4.1 1.1 2.0 3.5 2.9 2.9 4.4 3.1 3.4 4.9 3.5 4.1 3.6 4.6 4.1 16.4 6.4 12.4 2.3 64.4 37.9 108.5 20.3 40.9 0.0 17.6 11.3 1.8 24.3 15.7 3.7 0.0 4.2 35.0 53.0 9.8 33.1 5.2 15.1 15.2 30.8 22.8 22.5 3.0 31.5 7.3 35.4 65.2 29.1 50.9 3.8 5.0 3.5 18.4 3.3 1.7 33.3 8.2 15.1 74.9 3.4 4.7 44.7 24.9 3.7 112.5 0.8 7.2 1.5 2.5 37.4 90.3 2.6 108.8 145.3 48.0 19.4 7.4 0.3 6.6 28.9 27.3 1.1 1.7 27.7 31.8 9.9 53.8 4.1 16.8 89.7 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 RHEB RHEB2 ENSG00000106615 "Ras homolog, mTORC1 binding" Q15382 7 151466012-151520120 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 724.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019436 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "CAB019436: AB_2178777" "unprognostic (2.22e-2)" "unprognostic (2.29e-2)" "unprognostic (2.25e-2)" "unprognostic (9.47e-2)" "unprognostic (2.65e-2)" "unprognostic (3.08e-3)" "prognostic unfavorable (9.08e-5)" "unprognostic (9.37e-2)" "unprognostic (4.76e-3)" "unprognostic (9.76e-3)" "unprognostic (1.85e-3)" "unprognostic (3.67e-2)" "unprognostic (2.36e-3)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.91e-1)" "unprognostic (3.15e-1)" 118.6 136.8 124.2 62.0 127.4 108.1 100.9 124.3 173.8 77.1 108.4 130.2 52.9 116.2 160.1 73.0 90.2 56.3 134.4 136.9 133.0 103.7 98.4 93.1 44.3 124.5 129.1 87.0 86.5 81.6 84.3 104.9 130.2 83.0 60.5 106.8 72.4 97.0 193.5 66.9 62.6 114.5 121.5 63.6 85.2 47.3 130.2 71.8 98.9 160.8 47.6 117.2 76.8 125.3 335.9 100.3 173.3 165.7 211.5 172.3 131.3 241.7 211.1 198.0 240.4 145.0 354.0 86.4 370.3 215.2 517.4 111.6 126.3 116.8 255.5 91.7 96.9 73.7 113.2 109.5 329.6 137.7 115.2 132.7 183.1 158.1 211.1 207.7 155.2 128.6 231.7 387.1 276.5 216.7 196.0 195.7 285.7 241.5 145.0 94.1 152.6 173.9 233.1 118.4 166.3 208.6 245.4 235.0 283.0 167.7 88.0 169.9 171.0 156.1 65.5 271.9 395.5 145.2 212.2 123.8 376.9 252.7 432.0 39.5 34.1 47.0 24.8 30.5 41.0 23.6 34.2 31.5 26.7 23.9 24.5 30.5 33.9 36.5 34.4 47.0 37.3 39.6 124.2 127.4 124.3 173.8 136.9 133.0 124.5 129.1 130.2 121.5 130.2 125.3 230.5 60.9 45.8 72.5 87.3 398.2 611.3 272.9 114.4 72.8 187.7 179.2 102.0 81.5 169.0 108.5 18.8 207.0 111.9 126.2 416.7 211.7 53.4 107.7 102.6 168.8 98.2 122.9 64.7 213.3 384.1 179.0 40.8 160.8 106.1 95.0 103.9 137.6 233.9 121.1 49.6 76.3 290.9 111.1 384.6 33.2 112.2 174.5 318.4 29.0 114.3 473.6 65.9 30.2 30.6 271.5 109.2 151.6 119.9 620.3 87.8 296.6 85.0 68.7 124.9 149.4 312.2 355.1 173.4 144.7 405.6 421.1 110.4 86.9 79.7 724.9 RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 452.4 315.0 234.6 357.9 258.6 473.4 360.0 257.1 274.1 310.4 237.4 351.9 274.6 293.8 298.6 362.6 269.2 267.1 269.6 220.8 271.2 286.9 274.5 430.9 396.3 282.9 245.8 297.2 225.3 269.4 164.3 396.8 287.2 244.5 369.3 113.3 238.0 315.6 331.0 281.3 281.0 416.9 259.3 329.1 292.1 154.1 257.5 387.7 326.3 298.5 454.9 358.2 273.6 292.5 470.4 406.1 500.9 512.7 569.9 858.9 370.8 930.1 735.7 790.3 722.4 347.6 527.4 721.8 251.6 1404.1 448.8 259.5 560.4 630.6 817.6 505.7 323.3 678.8 488.0 416.0 604.2 647.9 472.8 668.2 437.8 643.2 508.1 799.7 1038.0 391.9 361.1 437.9 967.5 254.3 717.3 739.0 441.4 548.2 497.1 325.5 451.4 610.5 701.9 559.6 167.7 387.3 599.0 464.5 495.4 499.4 301.7 819.6 972.1 558.4 483.2 737.2 725.7 388.0 775.6 754.8 567.9 691.6 678.3 716.9 1105.5 1160.5 480.1 1358.8 423.8 432.7 415.6 479.6 806.9 379.3 314.5 397.1 1282.7 440.9 1398.1 645.5 554.9 1884.8 234.6 258.6 257.1 274.1 220.8 271.2 282.9 245.8 287.2 259.3 257.5 292.5 502.8 387.8 265.2 20.5 374.6 270.9 260.0 236.1 251.6 47.1 239.4 223.1 141.1 178.7 220.9 180.3 6.2 355.8 373.1 447.2 340.4 339.5 48.2 174.2 243.7 413.8 234.4 319.3 26.1 347.8 709.8 386.2 313.9 201.0 257.3 141.6 312.7 173.2 760.0 82.4 27.0 344.9 191.2 771.9 495.8 55.6 335.2 683.7 327.3 52.5 710.0 219.9 389.3 24.6 51.4 398.0 354.6 407.7 375.7 334.1 341.3 350.8 201.1 40.8 276.1 354.1 450.1 264.4 253.6 390.8 279.6 525.2 359.5 299.1 347.7 371.4 RHOB "ARH6, ARHB, MST081, RHOH6" ENSG00000143878 "Ras homolog family member B" P62745 2 20447074-20449440 "Cancer-related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Protein transport, Transport" "Developmental protein" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1272.8;Basal squamous epithelial cells: 1327.7;Hepatocytes: 1360.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 5.6;eosinophil: 18.0;intermediate monocyte: 11.4;neutrophil: 21.5;non-classical monocyte: 13.3" "Group enriched" "Detected in many" 13 "granulocytes: 21.5;monocytes: 13.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 297.9;RPTEC TERT1: 462.9;SK-BR-3: 561.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (9.66e-3)" "unprognostic (5.57e-3)" "unprognostic (8.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.85e-1)" "unprognostic (9.16e-3)" "unprognostic (5.41e-3)" "unprognostic (4.91e-2)" "unprognostic (1.04e-2)" "unprognostic (3.22e-2)" "unprognostic (3.29e-1)" "unprognostic (2.13e-2)" "prognostic favorable (4.23e-4)" "unprognostic (5.71e-2)" "unprognostic (2.56e-1)" "unprognostic (3.01e-2)" "unprognostic (2.49e-2)" 592.1 538.8 216.9 94.7 331.1 71.9 459.9 309.1 207.4 495.7 106.2 657.1 40.4 370.7 67.0 166.4 599.0 166.4 354.7 181.8 260.8 173.7 642.3 386.6 43.7 356.0 315.0 437.3 111.5 34.4 135.2 170.3 317.1 342.9 81.0 27.5 136.0 219.7 366.7 391.8 203.4 260.8 328.1 115.7 438.5 52.9 286.8 52.4 171.1 153.4 13.1 490.0 353.6 356.2 29.0 42.5 79.9 19.4 202.3 48.1 112.7 133.5 48.2 58.0 19.6 27.2 32.9 0.1 13.8 68.2 113.8 16.4 1.3 27.4 20.5 33.5 86.8 1.5 118.4 224.4 52.7 0.4 86.0 88.7 93.3 34.6 45.5 55.8 297.9 0.2 8.6 51.1 35.6 78.0 1.4 10.9 35.4 45.3 17.7 7.5 35.8 52.4 462.9 66.6 64.7 39.7 27.9 561.2 81.7 224.2 98.6 7.3 178.8 25.8 61.2 10.8 51.7 96.4 15.3 0.5 6.6 0.4 24.3 5.6 2.5 18.0 0.6 11.4 0.1 0.2 0.0 0.4 1.3 0.2 0.0 0.1 21.5 0.9 13.3 0.1 0.1 1.1 216.9 331.1 309.1 207.4 181.8 260.8 356.0 315.0 317.1 328.1 286.8 356.2 1272.8 48.1 101.9 238.3 118.7 73.9 281.4 53.0 1327.7 20.4 465.1 460.4 118.6 700.6 70.6 77.3 2.1 114.2 66.8 655.2 64.6 296.4 6.0 346.3 283.8 409.6 561.2 33.7 17.3 119.9 134.5 621.3 670.7 364.6 24.7 390.9 376.6 1360.8 190.1 33.7 18.2 496.4 73.2 418.1 136.4 20.9 270.6 473.4 96.0 43.1 31.6 344.8 5.2 32.6 91.9 200.8 318.8 197.5 191.6 212.1 203.1 289.0 89.1 19.3 927.0 542.5 800.5 6.5 22.5 701.2 90.5 270.1 62.5 244.6 340.7 85.2 RHOC "ARH9, ARHC" ENSG00000155366 "Ras homolog family member C" P08134 1 112701127-112707434 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1020.9;Pancreatic endocrine cells: 1304.7;Paneth cells: 945.4;Proximal enterocytes: 952.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1396.1" "Lineage enriched" "Detected in all" 4 "monocytes: 1396.1" "Cell line enhanced" "Detected in all" "WM-115: 2444.5" HPA051461 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA051461: AB_2681493" "unprognostic (2.31e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.93e-1)" "unprognostic (8.34e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.68e-4)" "unprognostic (2.08e-2)" "unprognostic (9.90e-2)" "unprognostic (1.40e-2)" "unprognostic (6.79e-3)" "unprognostic (3.95e-2)" "prognostic unfavorable (3.65e-5)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" "unprognostic (3.08e-2)" "unprognostic (2.51e-3)" 265.2 201.7 183.2 122.7 184.1 20.8 239.2 177.4 207.7 204.7 169.7 297.2 293.2 254.7 312.7 105.1 200.5 185.9 333.8 176.1 209.5 304.7 144.7 278.8 55.3 209.2 192.0 189.1 120.1 643.1 110.0 226.9 194.8 232.1 250.5 87.6 149.3 282.7 85.8 165.7 311.4 253.0 192.8 231.6 150.2 93.9 204.6 88.8 160.8 119.9 50.5 218.8 179.8 180.3 774.3 314.4 178.1 203.7 334.3 571.7 204.7 672.2 825.1 476.1 402.8 253.8 236.1 10.6 281.8 1000.8 221.5 217.5 136.2 630.2 456.9 181.7 83.9 89.1 201.2 202.9 559.5 14.3 394.1 687.8 421.1 804.3 535.4 543.3 1286.4 108.3 180.5 157.1 876.7 410.2 38.7 72.4 49.5 300.7 567.0 65.7 208.7 34.8 572.1 212.8 8.3 79.6 346.2 218.5 436.6 348.5 482.0 66.6 1113.9 651.1 459.7 905.9 505.9 99.8 90.4 33.0 739.2 59.1 2444.5 1.7 68.8 1.8 216.7 805.0 144.6 49.5 41.6 87.5 244.1 65.9 10.1 65.9 18.2 346.9 1396.1 185.7 51.3 315.6 183.2 184.1 177.4 207.7 176.1 209.5 209.2 192.0 194.8 192.8 204.6 180.3 576.7 16.0 33.3 10.4 28.2 184.4 308.2 443.8 63.2 2.2 224.6 231.8 84.4 92.9 180.1 239.1 4.2 328.5 118.2 1020.9 164.4 755.7 13.2 73.0 132.3 424.6 84.9 21.0 0.2 839.7 495.0 181.4 62.2 102.4 62.7 75.5 335.2 50.3 162.4 6.7 0.2 248.7 166.8 92.7 290.7 39.2 150.1 146.3 245.5 11.2 299.1 550.3 289.4 11.1 1.1 1304.7 945.4 206.9 12.6 380.2 952.7 705.3 71.1 15.3 216.9 95.3 292.6 13.6 42.0 54.8 168.6 258.6 108.8 205.5 209.6 422.0 RHOH "ARHH, TTF" ENSG00000168421 "Ras homolog family member H" Q15669 4 40191053-40246967 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.9;lymphoid tissue: 98.2" "Cell type enhanced" "Detected in many" "B-cells: 273.0;dendritic cells: 90.5;granulocytes: 141.8;NK-cells: 64.9;Plasma cells: 183.1;T-cells: 223.6" "Cancer enhanced" "Detected in many" "breast cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 126.3;HMC-1: 92.5;JURKAT: 123.7;MOLT-4: 179.4;U-266/70: 65.5;U-266/84: 56.8;U-698: 116.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030345, HPA061314" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Vesicles" "HPA030345: AB_10601607, HPA061314: " "unprognostic (4.00e-2)" "unprognostic (1.83e-4)" "unprognostic (1.24e-2)" "unprognostic (2.22e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-3)" "unprognostic (1.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.30e-2)" "unprognostic (4.30e-2)" "unprognostic (9.07e-2)" "unprognostic (1.38e-1)" "unprognostic (3.31e-6)" "unprognostic (2.96e-1)" "unprognostic (3.91e-2)" "unprognostic (4.46e-2)" "unprognostic (2.44e-2)" 2.2 0.9 0.7 36.4 0.6 62.9 13.2 0.5 0.8 2.9 0.6 6.3 4.8 1.6 0.9 2.9 1.5 6.4 0.7 0.6 0.8 1.2 2.7 5.7 86.0 1.1 1.3 0.9 1.4 0.4 0.7 0.9 0.9 2.7 5.6 0.0 3.9 0.9 0.6 1.2 20.6 1.5 1.0 42.6 8.2 0.7 0.8 98.2 1.8 0.3 85.2 10.6 1.6 1.0 0.2 0.4 0.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 126.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 2.6 0.0 18.8 0.1 0.0 0.0 21.1 92.5 1.5 0.0 0.0 0.0 0.1 0.1 123.7 1.4 1.2 0.0 0.0 179.4 13.3 2.3 0.0 0.4 19.1 0.3 4.3 0.0 0.0 0.1 0.1 0.3 0.8 0.2 0.1 5.7 0.5 0.5 0.0 0.5 0.1 0.2 65.5 56.8 116.3 0.1 4.4 0.1 210.3 1.1 168.7 112.2 0.8 99.3 164.3 176.9 151.1 1.9 212.1 274.3 220.5 8.4 74.2 1.2 26.1 268.4 124.1 0.7 0.6 0.5 0.8 0.6 0.8 1.1 1.3 0.9 1.0 0.8 1.0 2.9 3.2 9.9 0.3 273.0 7.1 1.4 0.3 1.8 0.0 11.1 6.7 1.1 1.5 2.9 0.0 0.0 0.1 90.5 0.3 0.0 0.1 0.6 0.6 0.5 2.3 0.0 23.4 0.3 0.0 0.2 3.6 9.7 1.0 141.8 0.0 1.8 0.2 2.2 0.0 0.3 0.4 0.0 4.4 16.2 0.7 0.0 28.4 56.9 8.4 11.3 0.0 64.9 0.5 0.1 0.0 0.1 0.0 183.1 1.4 0.0 0.4 1.0 0.0 0.0 2.0 2.0 0.3 0.2 0.3 7.0 0.3 223.6 0.1 0.3 2.0 RIT1 "MGC125864, MGC125865, RIBB, RIT, ROC1" ENSG00000143622 "Ras like without CAAX 1" Q92963 1 155897808-155911404 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 80.7" "Cell type enhanced" "Detected in all" "Langerhans cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053249 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "HPA053249: AB_2682089" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (7.27e-2)" "unprognostic (3.66e-2)" "unprognostic (1.35e-2)" "unprognostic (3.11e-2)" "prognostic unfavorable (8.64e-6)" "unprognostic (3.80e-2)" "unprognostic (4.99e-2)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (2.19e-2)" "unprognostic (9.22e-3)" "unprognostic (4.82e-2)" "unprognostic (3.74e-1)" "unprognostic (1.51e-1)" "unprognostic (2.33e-3)" 19.8 13.8 10.7 22.9 12.1 80.7 13.3 12.0 13.0 16.6 12.1 14.0 12.7 14.8 15.4 37.3 10.8 18.5 15.7 10.3 11.8 25.1 12.2 22.7 18.3 13.5 12.7 12.8 13.8 16.5 11.0 23.0 13.3 13.8 14.3 16.0 14.4 18.0 10.8 12.8 12.5 21.3 11.6 21.7 19.7 12.2 12.8 21.5 13.4 16.5 23.6 23.6 21.9 13.3 21.0 22.9 42.3 21.7 21.5 26.6 12.0 37.2 37.4 35.2 35.4 24.1 40.0 9.6 50.0 43.9 25.3 24.7 32.0 18.5 29.4 12.9 16.4 21.0 24.4 15.6 55.7 22.5 37.9 37.1 22.5 40.9 27.4 47.7 48.7 19.7 21.0 26.3 54.3 27.3 30.7 14.9 23.0 36.2 13.9 24.0 33.3 19.6 29.9 44.2 19.7 30.7 27.1 51.1 34.8 76.9 37.3 29.4 62.5 31.7 22.3 27.3 30.7 31.1 30.9 38.8 33.9 22.8 43.0 22.8 41.0 46.9 19.5 25.5 15.6 16.9 16.8 18.5 31.1 17.1 20.2 18.1 106.3 28.8 29.3 12.5 23.8 30.0 10.7 12.1 12.0 13.0 10.3 11.8 13.5 12.7 13.3 11.6 12.8 13.3 45.8 48.1 23.9 12.4 22.4 28.9 36.5 43.7 21.6 8.1 17.4 12.3 14.2 8.6 40.4 18.4 10.4 14.5 41.8 14.1 21.5 39.4 10.4 20.4 25.7 50.5 12.6 16.4 5.1 23.4 16.8 20.8 13.3 32.5 14.0 15.2 24.7 7.0 50.7 6.7 5.3 11.5 42.7 45.6 107.9 10.3 7.2 62.6 33.8 11.2 79.2 25.9 16.5 8.5 8.1 28.3 15.4 15.8 13.4 48.8 15.4 70.6 21.9 11.9 26.3 18.2 26.1 12.7 23.2 26.0 30.7 33.5 32.7 20.7 10.0 79.2 RMC1 "C18orf8, HsT2591, MIC1, WDR98" ENSG00000141452 "Regulator of MON1-CCZ1" Q96DM3 18 23503470-23531822 "Cancer-related genes, Predicted intracellular proteins" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 14.5;Proximal tubular cells: 19.9;Syncytiotrophoblasts: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043589 Uncertain Uncertain Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA043589: AB_2678568" "unprognostic (6.45e-2)" "unprognostic (6.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.51e-3)" "unprognostic (8.16e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-1)" "unprognostic (3.03e-1)" "unprognostic (3.76e-1)" "unprognostic (1.25e-1)" "unprognostic (3.04e-2)" "unprognostic (4.13e-2)" 12.8 9.8 4.9 11.2 6.0 27.4 11.2 5.5 7.3 10.9 8.5 11.1 16.7 11.2 9.3 11.7 10.6 10.3 8.8 6.2 6.6 13.0 19.1 14.4 21.3 5.3 4.8 9.6 11.7 11.4 16.6 8.5 5.7 9.3 10.9 25.4 12.2 10.6 13.4 12.5 17.1 10.6 5.1 15.6 14.6 17.2 5.3 15.8 9.8 7.4 19.1 14.8 10.5 7.2 13.9 13.9 10.3 18.1 23.0 16.6 13.5 21.5 22.8 28.2 33.6 12.9 8.1 20.8 17.5 18.7 40.9 26.6 27.1 12.0 24.8 21.6 15.4 10.2 8.7 13.1 30.1 27.7 36.0 14.9 18.6 35.2 19.8 16.2 16.9 17.7 16.7 21.9 18.8 18.1 23.8 13.0 5.6 19.7 21.4 18.3 15.4 20.4 14.7 13.0 13.8 17.9 28.1 13.7 18.2 14.2 10.5 17.6 16.2 23.6 6.0 9.8 18.6 34.1 27.4 23.6 24.5 18.7 18.4 50.5 16.4 37.7 23.8 31.0 24.5 32.5 20.7 23.3 20.0 29.5 14.0 17.2 15.2 32.9 44.5 44.5 30.5 18.7 4.9 6.0 5.5 7.3 6.2 6.6 5.3 4.8 5.7 5.1 5.3 7.2 9.1 9.6 13.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.6 5.8 0.0 0.0 3.7 7.3 0.0 10.7 13.4 0.0 5.9 11.6 0.0 11.4 5.9 2.9 0.0 0.0 0.0 12.1 7.6 3.4 0.0 14.5 3.8 8.7 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.8 0.0 0.0 0.0 0.0 11.3 0.0 0.0 1.9 0.0 0.0 19.9 1.5 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 19.2 6.3 8.3 0.0 0.0 RMI2 "BLAP18, C16orf75, MGC24665" ENSG00000175643 "RecQ mediated genome instability 2" Q96E14 16 11249619-11381662 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.8;Erythroid cells: 38.5;Extravillous trophoblasts: 34.1;Peritubular cells: 42.5;Spermatocytes: 36.6;Spermatogonia: 51.8;Syncytiotrophoblasts: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 4.2" "Group enriched" "Detected in many" 6 "B-cells: 4.2;T-cells: 1.4" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040995 Uncertain Supported "Nuclear speckles,Cytosol" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" Cytosol "HPA040995: AB_10795531" "unprognostic (2.76e-1)" "prognostic favorable (5.69e-5)" "unprognostic (1.17e-1)" "unprognostic (3.09e-3)" "unprognostic (1.69e-2)" "unprognostic (1.80e-3)" "prognostic unfavorable (2.77e-5)" "unprognostic (3.98e-1)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.44e-3)" "unprognostic (3.89e-1)" "unprognostic (2.18e-1)" "unprognostic (5.50e-2)" "unprognostic (3.68e-2)" "unprognostic (3.60e-3)" "unprognostic (1.03e-1)" 1.4 1.5 2.2 12.3 2.0 9.9 5.1 1.0 2.2 4.8 0.9 12.5 7.5 2.9 3.9 10.8 2.1 2.2 1.6 2.3 1.3 3.4 4.3 1.9 31.4 1.2 1.3 3.0 1.8 1.3 0.6 19.3 1.2 3.2 14.4 0.5 2.4 2.1 0.9 10.2 8.8 2.3 1.0 3.5 7.0 14.0 1.4 36.8 1.5 0.6 34.9 4.5 4.4 1.8 60.3 39.5 75.2 32.6 3.3 15.8 33.0 35.9 26.8 31.6 51.8 15.4 69.2 83.8 29.1 15.8 35.3 34.4 32.4 32.5 50.5 16.6 30.5 45.3 22.6 102.5 1.3 17.6 19.5 3.7 6.1 14.5 13.3 12.3 17.4 36.2 65.3 63.2 16.5 70.3 60.9 83.1 64.1 82.6 15.7 73.1 81.1 89.3 18.7 38.0 44.1 35.0 28.5 47.4 26.1 43.5 80.4 25.8 5.6 25.1 23.3 49.3 5.0 18.1 30.9 99.3 23.3 57.4 47.2 0.0 0.0 0.4 0.3 0.0 0.0 4.2 0.1 0.0 0.2 1.1 0.8 0.3 0.1 0.1 0.0 0.2 1.4 0.1 2.2 2.0 1.0 2.2 2.3 1.3 1.2 1.3 1.2 1.0 1.4 1.8 1.3 0.0 0.5 0.0 4.5 6.8 5.4 1.4 6.2 0.2 3.4 3.2 1.0 4.3 1.6 7.3 0.0 123.8 0.5 3.3 5.9 2.6 3.0 0.8 2.1 2.8 2.4 38.5 0.0 0.5 34.1 6.4 4.1 2.2 0.0 19.7 1.1 1.1 18.5 0.0 0.0 7.7 0.0 0.8 6.5 5.9 15.8 3.7 3.6 0.0 1.1 0.2 1.0 0.0 0.0 1.0 4.0 42.5 2.4 2.1 1.3 0.4 0.1 0.6 32.9 0.0 2.2 36.6 51.8 11.3 5.4 47.7 1.9 6.5 10.3 7.5 RNF213 "ALO17, C17orf27, KIAA1554, KIAA1618, MYMY2, NET57" ENSG00000173821 "Ring finger protein 213" Q63HN8 17 80260866-80398786 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Ubl conjugation pathway" "Hydrolase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 396.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 90.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003347, HPA026790" Approved Supported Cytosol NA NA 3500 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA003347: AB_1079204, HPA026790: AB_10602296" "unprognostic (8.98e-2)" "unprognostic (1.60e-1)" "unprognostic (8.97e-3)" "prognostic unfavorable (4.65e-5)" "unprognostic (7.39e-2)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.85e-1)" "unprognostic (1.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-3)" "unprognostic (8.92e-2)" "unprognostic (1.13e-2)" "unprognostic (1.40e-1)" "unprognostic (4.56e-2)" 7.4 9.9 6.8 18.6 12.9 25.6 7.0 9.0 11.3 8.0 13.0 9.0 8.7 7.8 8.7 7.1 8.6 10.7 6.5 5.1 6.9 10.5 6.2 13.2 17.9 23.5 11.4 9.0 7.8 34.2 6.6 10.0 18.3 7.1 7.8 12.0 10.8 6.8 6.6 8.8 10.6 9.1 13.8 18.7 11.1 3.4 16.5 20.2 11.0 7.6 14.5 11.0 7.1 17.3 40.1 69.7 6.9 4.9 24.4 37.0 5.1 9.9 21.4 43.7 37.1 7.5 18.1 2.6 8.3 20.8 46.6 22.7 9.3 12.9 14.7 90.8 4.3 6.3 29.9 13.3 10.5 6.7 6.2 20.5 8.6 24.6 10.6 13.7 34.3 28.3 11.8 14.5 16.5 9.7 26.7 2.8 5.1 7.5 16.0 18.0 15.9 3.1 12.1 34.1 6.6 9.2 24.1 50.3 17.3 15.3 11.6 8.2 44.5 24.2 19.0 14.4 10.3 6.3 6.3 7.0 18.2 7.6 8.9 19.5 20.8 10.4 26.2 18.5 17.5 15.3 18.6 21.6 5.4 15.5 14.6 18.2 84.5 26.1 17.1 32.0 15.4 4.8 6.8 12.9 9.0 11.3 5.1 6.9 23.5 11.4 18.3 13.8 16.5 17.3 76.1 89.8 56.9 56.8 89.9 35.8 37.2 39.2 43.3 21.2 59.9 41.7 32.6 75.8 50.3 101.2 50.1 21.0 240.8 117.4 13.7 120.3 1.4 58.7 58.9 90.7 46.0 30.3 23.6 162.4 31.5 50.8 158.0 93.4 46.7 140.7 74.3 56.4 98.0 23.5 15.5 68.2 32.6 136.5 94.9 3.7 60.9 128.9 30.2 87.1 194.6 26.1 396.5 32.2 70.4 166.1 76.2 51.6 167.6 100.8 116.3 92.2 66.2 68.5 65.7 52.3 53.7 1.4 8.2 43.0 34.4 21.8 211.6 84.7 54.9 66.5 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.7;Intestinal goblet cells: 41.6;Undifferentiated cells: 63.6" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 41.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.0;CACO-2: 24.7;Hep G2: 49.4;OE19: 54.7" HPA008079 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.2 10.9 1.7 2.0 3.1 0.7 5.5 9.6 2.7 2.6 1.5 13.4 22.7 1.7 4.4 10.4 4.8 2.7 2.7 2.0 1.3 6.1 9.1 3.6 0.4 1.8 3.4 0.9 8.2 5.2 4.3 4.8 1.9 9.4 19.3 1.2 9.3 4.8 0.3 11.3 16.9 0.6 1.4 0.5 5.8 3.4 2.3 3.7 1.9 0.0 1.5 2.1 5.2 1.4 1.1 17.0 2.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 24.7 8.2 0.0 8.5 0.0 1.9 4.6 0.6 6.8 0.0 8.6 11.3 1.9 0.8 49.4 0.0 0.2 0.1 0.0 13.4 0.0 2.1 0.0 0.0 0.2 0.2 0.4 0.0 0.2 0.1 0.2 0.4 54.7 1.0 0.3 0.0 2.2 5.9 9.0 1.6 0.1 1.6 0.7 0.5 5.4 2.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.4 0.1 0.3 0.0 3.8 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.2 0.0 1.7 3.1 9.6 2.7 2.0 1.3 1.8 3.4 1.9 1.4 2.3 1.4 0.3 3.2 8.9 29.0 2.5 9.6 17.5 14.1 67.7 2.5 17.3 13.6 4.0 17.2 5.8 18.4 2.1 26.0 2.2 33.0 15.6 5.3 1.2 14.6 1.1 1.8 15.5 0.8 1.8 2.7 3.1 0.7 9.7 12.7 0.0 7.2 0.7 11.9 2.6 5.0 1.3 41.6 12.2 0.8 0.9 1.5 0.3 1.3 14.2 4.7 2.8 12.0 10.3 0.0 0.7 6.2 21.1 0.4 1.0 9.9 28.7 2.9 5.6 2.8 0.0 0.5 1.1 1.0 0.8 28.4 6.1 5.9 3.1 0.4 63.6 6.3 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 58.6;lung: 31.7" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 78.5" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "GAMG: 19.3;HSkMC: 10.1;hTCEpi: 21.7;LHCN-M2: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.0 58.6 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.1 31.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 2.2 0.4 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.1 21.7 0.2 1.9 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.0 0.0 3.1 1.7 0.2 2.1 0.0 0.0 0.0 1.9 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.0 78.5 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.8 0.0 3.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.3 1.8 0.2 0.0 0.0 0.0 17.8 0.0 0.0 0.2 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 RPA2 ENSG00000117748 "Replication protein A2" P15927 1 27891524-27914746 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 162.3;Spermatogonia: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016538, HPA026306, HPA026309" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "CAB016538: AB_670974, HPA026306: AB_10598913, HPA026309: AB_10601572" "unprognostic (2.59e-1)" "prognostic favorable (4.33e-4)" "unprognostic (8.98e-2)" "unprognostic (6.89e-2)" "unprognostic (1.04e-1)" "prognostic favorable (8.12e-4)" "unprognostic (4.29e-3)" "unprognostic (2.03e-2)" "unprognostic (8.62e-3)" "unprognostic (1.68e-1)" "unprognostic (1.58e-2)" "unprognostic (2.31e-1)" "unprognostic (3.59e-2)" "unprognostic (9.13e-2)" "unprognostic (2.30e-1)" "unprognostic (2.18e-3)" "unprognostic (2.82e-2)" 28.4 25.0 33.3 39.7 35.1 40.7 43.8 33.4 42.4 32.0 37.4 26.6 18.5 33.7 43.4 32.3 49.1 30.6 39.2 34.5 36.1 32.4 31.8 28.7 75.1 33.7 33.2 52.0 21.0 40.7 31.3 30.2 33.9 28.7 30.2 43.8 24.0 31.3 72.3 40.3 26.1 30.7 36.7 42.3 25.6 63.7 34.0 53.4 52.9 63.2 67.6 30.3 24.9 36.7 60.9 57.4 86.4 68.5 59.3 52.8 57.2 106.1 70.3 130.0 113.5 80.2 72.7 148.9 69.4 41.1 48.4 55.8 126.5 60.3 122.4 121.0 126.0 174.3 73.0 71.3 30.9 229.7 115.1 24.6 33.2 123.8 62.3 40.3 59.1 133.1 196.2 127.1 75.7 63.6 163.9 105.1 181.7 115.1 122.0 115.0 128.7 74.2 49.1 65.2 78.3 75.8 123.3 47.3 100.7 68.1 50.9 71.8 36.6 32.2 73.0 186.2 76.3 105.8 251.0 135.8 81.4 213.5 64.3 322.3 97.4 290.0 279.7 80.0 304.4 272.5 252.9 257.4 112.1 232.0 287.4 282.7 100.1 294.1 106.5 172.3 255.5 435.5 33.3 35.1 33.4 42.4 34.5 36.1 33.7 33.2 33.9 36.7 34.0 36.7 26.5 22.4 15.7 10.4 64.0 21.0 28.5 47.1 16.5 28.4 25.7 27.8 29.0 24.3 30.4 22.0 2.1 95.2 77.8 10.1 35.2 35.0 49.0 14.6 18.8 27.9 13.8 39.1 8.8 20.6 67.3 34.8 7.1 15.1 60.9 33.3 26.4 16.6 51.9 8.4 8.4 14.0 71.2 31.5 27.6 22.6 41.3 34.1 37.4 7.5 86.7 100.0 95.8 9.5 14.3 29.5 10.4 46.3 32.6 19.3 11.2 23.6 28.8 34.5 32.9 48.0 24.7 162.3 183.5 20.6 22.4 55.7 59.9 33.9 19.3 20.1 RPGR "COD1, CORDX1, CRD, RP15, RP3" ENSG00000156313 "Retinitis pigmentosa GTPase regulator" Q92834 X 38269163-38327544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Cancer-related genes, Ciliopathy, Cone-rod dystrophy, Deafness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 146.1;Hepatic stellate cells: 121.7;Respiratory ciliated cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 14.6" "Cell line enhanced" "Detected in many" "HL-60: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001593, HPA073455" Approved Supported "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "HPA001593: AB_1079835, HPA073455: AB_2686603" "unprognostic (3.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.04e-2)" "unprognostic (1.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.94e-2)" "unprognostic (3.46e-2)" "unprognostic (6.32e-2)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-6)" "unprognostic (1.93e-1)" "unprognostic (7.59e-2)" "unprognostic (8.96e-3)" "unprognostic (1.61e-3)" 19.2 5.7 4.7 4.4 4.6 12.2 16.8 5.2 5.5 10.2 15.5 9.1 3.0 11.6 2.5 5.5 15.0 5.5 9.8 4.6 6.3 6.2 3.7 14.8 3.7 7.6 7.0 6.2 7.5 2.6 32.9 3.7 5.8 6.9 3.6 12.1 5.2 2.6 12.1 6.0 9.4 4.5 6.6 5.1 6.8 8.1 5.3 4.7 9.7 3.7 3.2 8.7 8.2 5.4 4.7 6.0 3.4 3.2 3.6 5.2 2.7 5.8 6.5 4.1 4.8 2.7 2.6 7.1 1.8 3.9 3.4 4.4 4.1 1.8 5.6 7.5 7.9 2.5 2.7 5.5 3.3 31.8 5.8 8.0 2.4 8.7 9.2 1.6 18.9 7.5 3.3 0.0 5.7 1.5 9.1 17.7 8.7 2.9 7.5 6.8 11.7 6.4 3.6 3.0 2.7 5.2 6.4 2.6 7.2 5.1 1.7 5.4 22.4 4.5 8.0 10.7 7.2 1.9 3.9 6.0 10.6 6.1 6.2 1.3 2.6 5.9 1.3 2.4 2.9 1.9 1.5 1.8 2.6 1.5 2.2 1.8 14.6 1.7 2.0 1.8 1.9 1.8 4.7 4.6 5.2 5.5 4.6 6.3 7.6 7.0 5.8 6.6 5.3 5.4 75.2 16.0 32.6 21.2 21.8 7.9 13.5 6.6 7.4 29.5 8.8 8.8 8.0 8.6 18.0 1.8 62.6 5.8 14.0 12.6 3.9 15.3 51.4 146.1 30.4 61.3 17.4 5.5 21.8 8.6 9.5 11.8 9.2 21.0 20.3 73.5 121.7 9.7 7.8 35.3 20.0 13.5 10.2 16.2 8.4 9.1 7.8 14.5 5.4 18.7 15.5 9.4 14.4 9.0 17.1 9.9 8.9 4.5 11.0 10.2 5.0 3.1 119.2 85.7 0.0 23.1 12.9 24.9 25.3 4.8 5.8 8.2 17.2 6.6 8.9 11.2 RPL10 "DXS648, DXS648E, FLJ23544, L10, NOV, QM" ENSG00000147403 "Ribosomal protein L10" P27635 X 154389955-154409168 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Developmental protein, Ribonucleoprotein, Ribosomal protein" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB010339, HPA011311" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 520000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "CAB010339: AB_2181277, HPA011311: AB_1856431" "unprognostic (2.46e-3)" "unprognostic (3.57e-2)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.25e-2)" "unprognostic (2.06e-1)" "unprognostic (6.11e-2)" "unprognostic (9.01e-3)" "unprognostic (1.91e-1)" "unprognostic (2.21e-1)" "unprognostic (5.39e-2)" "unprognostic (3.37e-1)" "prognostic unfavorable (7.67e-6)" "unprognostic (6.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.65e-2)" "unprognostic (5.68e-2)" 3787.4 2419.1 1394.0 2169.7 1436.7 4648.6 4838.0 1413.7 1627.7 4522.8 1418.2 3090.4 1960.7 3234.2 2327.8 3175.9 4434.1 1996.7 2795.8 1340.4 1450.2 2318.6 2457.5 2593.7 4447.8 1490.4 1395.4 7892.2 8248.7 1574.9 1262.1 1879.3 1495.2 2998.1 2852.0 605.3 3991.5 2220.8 4760.6 4580.4 2644.6 2899.6 1535.3 3002.5 3262.2 372.8 1456.6 3691.0 2499.0 3882.7 5285.1 3395.7 3633.5 1537.6 5771.5 2604.6 2556.3 1973.1 5665.6 10627.4 2257.6 2147.4 4944.5 4036.4 5092.8 2323.7 2507.2 11250.6 5101.5 3609.5 4017.7 2175.5 5072.8 5166.9 3441.7 2507.6 4032.6 1534.4 1719.4 2591.8 6623.5 3314.4 2163.5 8104.7 8023.2 2435.8 7540.7 6953.8 6482.3 4734.1 2197.3 3482.7 4027.7 2869.8 3643.7 3212.1 2023.6 5617.9 4482.1 4301.7 2425.2 6334.8 4477.5 2015.0 2043.5 3397.3 526.0 4516.0 6630.0 2442.8 1643.7 4541.0 3144.3 1405.7 2655.1 3210.9 4865.5 8226.6 6458.7 11466.6 2139.0 4722.1 1803.6 2544.3 4388.3 622.1 4542.5 3596.8 7775.4 8121.0 7534.8 5653.3 4873.3 7698.6 8993.4 6990.0 410.0 5161.3 3275.5 5417.4 5907.4 18184.4 1394.0 1436.7 1413.7 1627.7 1340.4 1450.2 1490.4 1395.4 1495.2 1535.3 1456.6 1537.6 5788.7 1791.6 2556.0 46.7 10527.8 12070.0 13158.5 11320.6 8610.2 480.8 13969.8 18711.5 332.5 4499.5 4867.7 2039.7 248.1 6871.3 8329.8 1997.2 6751.9 4614.2 76.2 2214.5 6544.8 5970.8 2893.6 4044.6 45.3 13505.4 10754.4 5761.0 3039.8 3854.9 2982.2 5292.3 6493.4 4196.6 7070.4 269.2 50.7 6837.3 3196.2 8756.2 13887.5 284.8 8462.7 6722.9 8167.8 49.6 10601.8 1879.6 6844.6 56.3 89.0 7721.0 5174.6 3567.3 7282.8 12796.7 5976.0 8673.5 1751.3 859.1 2991.1 7996.0 6645.8 94.6 354.5 9576.3 14556.9 7562.7 9597.3 5236.0 6657.3 13414.3 RPL22 "EAP, L22" ENSG00000116251 "Ribosomal protein L22" P35268 1 6185020-6209389 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Heparin-binding, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA068294 Approved Nucleoplasm,Nucleoli NA NA 860000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Nucleoli Nucleoplasm "HPA068294: AB_2732781" "unprognostic (3.16e-3)" "unprognostic (1.28e-1)" "unprognostic (3.13e-1)" "unprognostic (3.62e-2)" "unprognostic (2.27e-2)" "unprognostic (1.09e-1)" "unprognostic (1.29e-3)" "unprognostic (4.40e-2)" "unprognostic (7.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.48e-1)" "unprognostic (4.24e-2)" "unprognostic (1.46e-3)" "unprognostic (3.83e-1)" "unprognostic (3.88e-2)" "unprognostic (2.46e-1)" "unprognostic (1.98e-1)" 579.0 489.0 252.3 511.9 262.0 1064.4 599.4 258.1 400.1 716.0 257.9 573.4 475.0 513.3 313.9 621.7 590.5 220.4 390.9 243.7 261.0 473.0 480.3 396.9 659.8 256.3 250.3 1096.7 690.5 312.2 331.9 308.3 259.9 487.3 320.3 316.6 589.4 218.3 912.3 686.8 461.4 247.4 263.7 501.7 500.7 137.8 255.5 484.9 400.4 398.8 509.7 551.5 600.5 274.7 1443.4 400.8 836.4 858.6 576.1 897.0 659.0 1224.2 488.1 440.4 372.9 802.5 1213.4 2217.7 981.3 458.1 304.2 810.7 636.9 638.2 576.9 1093.6 1033.3 2159.0 948.8 1016.3 569.4 2893.0 828.4 799.9 516.3 393.5 808.6 907.3 560.1 610.3 1817.3 1301.1 512.9 634.7 1274.0 2340.3 522.1 953.0 880.1 1207.4 1731.8 1731.8 656.1 490.4 1149.9 1051.9 996.9 2846.8 2387.4 721.1 918.2 2247.5 1380.1 623.1 689.2 833.9 1170.4 1037.2 1544.9 3289.7 413.0 2911.2 395.5 109.0 297.7 71.2 268.2 270.0 474.9 547.1 502.6 373.2 451.6 500.6 679.0 560.8 22.0 337.5 227.9 472.2 416.3 664.1 252.3 262.0 258.1 400.1 243.7 261.0 256.3 250.3 259.9 263.7 255.5 274.7 1090.2 445.5 731.5 5.9 2372.5 1821.1 2035.3 1455.3 2241.2 217.6 1764.0 2190.8 277.9 1225.3 883.4 584.9 131.3 1816.1 1450.8 669.0 1905.6 1332.1 442.9 736.9 1377.2 1104.5 912.5 1508.9 15.3 1823.0 2751.0 1022.5 940.9 944.1 921.5 1256.6 1457.4 1491.7 1504.9 141.3 14.2 2032.2 449.6 1997.8 2098.8 320.1 2027.4 1440.8 1076.1 14.0 2435.3 890.1 1442.9 8.0 10.7 1575.3 1413.5 1234.1 1218.7 1837.3 1182.5 2505.6 437.3 390.8 775.7 1773.9 1169.1 358.6 473.0 2759.8 1935.8 1851.9 1791.5 1289.9 2231.0 2084.3 RPL27 L27 ENSG00000131469 "Ribosomal protein L27" P61353 17 42998273-43002959 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cancer-related genes, Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA002649 Approved Enhanced Nucleoplasm,Nucleoli NA NA 170000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Nucleoli Nucleoplasm "HPA002649: AB_1079840" "unprognostic (8.53e-3)" "unprognostic (7.15e-2)" "unprognostic (3.97e-2)" "unprognostic (2.81e-2)" "unprognostic (4.99e-2)" "unprognostic (4.31e-2)" "unprognostic (1.91e-3)" "unprognostic (7.32e-2)" "unprognostic (9.17e-2)" "unprognostic (1.19e-1)" "unprognostic (5.12e-2)" "unprognostic (3.86e-1)" "prognostic unfavorable (7.80e-8)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" 1871.8 1549.8 1111.3 1009.9 1116.5 2929.2 1962.9 1098.5 1512.7 2052.8 1111.9 1884.1 802.3 1550.5 994.9 1984.2 1652.8 740.8 1495.4 1092.8 1126.1 1276.4 1316.9 1278.5 1999.4 1122.6 1109.6 2598.8 2232.2 850.4 894.8 951.0 1119.0 1483.8 894.1 394.5 1530.7 749.8 2544.6 2726.6 1467.8 854.4 1124.4 1802.0 1559.6 409.4 1127.1 1682.4 1067.7 1510.1 1378.5 1650.9 1820.8 1132.8 2288.0 2867.0 1701.7 2480.6 2983.9 4422.4 2741.5 2594.6 2162.4 2777.2 1979.1 4107.0 1751.0 4309.7 2143.3 2087.9 1477.4 1948.8 2000.9 3363.7 2670.5 1996.4 4741.8 1694.3 2147.4 4431.8 3669.4 4908.1 1698.9 4175.7 2847.4 1867.0 2381.3 2795.0 2356.9 2241.9 3237.8 2584.2 2618.6 2253.4 4127.7 4153.0 2577.8 2634.0 1821.4 2841.1 4775.1 4927.8 2374.2 3092.9 1909.6 2094.8 1016.8 1982.1 4341.5 2299.8 3341.2 5076.5 2617.1 2021.7 1988.7 2497.2 3885.7 2219.6 4004.7 4327.4 1816.5 3030.7 2107.7 1007.1 1762.8 553.5 1773.1 1633.6 2518.3 3055.1 2633.3 2095.8 2115.1 2792.7 2987.8 2673.6 358.7 2155.7 1284.9 2726.2 2059.6 4601.4 1111.3 1116.5 1098.5 1512.7 1092.8 1126.1 1122.6 1109.6 1119.0 1124.4 1127.1 1132.8 770.3 734.0 1103.9 11.1 2217.2 2530.2 2296.2 1759.2 941.8 138.9 1779.8 1725.0 725.8 1302.6 1175.0 518.6 89.6 2093.8 1873.8 948.5 1496.7 1822.6 435.6 524.0 1202.0 1245.7 912.0 1291.4 9.9 3028.9 3551.3 1025.1 510.7 660.9 991.3 983.7 1689.1 1859.0 2118.7 65.6 10.7 2016.4 671.4 2560.1 2977.0 1070.0 2434.3 1522.8 1426.5 22.5 3232.7 722.9 2669.4 7.5 16.3 2450.0 1585.4 1279.6 957.2 2462.7 1301.2 2383.0 574.6 230.6 867.8 1669.6 1874.7 384.8 476.4 1644.1 3371.3 2184.8 1833.0 1266.3 2175.4 2628.2 RPL5 "L5, PPP1R135, uL18" ENSG00000122406 "Ribosomal protein L5" P46777 1 92832013-92841924 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Cancer-related genes, Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA043717, HPA054444" Approved Supported "Nucleoli,Nucleoli rim,Endoplasmic reticulum,Cytosol" NA NA 430000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoli, Nucleoli rim" "HPA043717: AB_10964719, HPA054444: AB_2732584" "unprognostic (5.81e-3)" "unprognostic (3.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (9.44e-3)" "unprognostic (1.96e-1)" "unprognostic (1.03e-3)" "unprognostic (9.95e-2)" "unprognostic (8.68e-2)" "unprognostic (1.23e-1)" "unprognostic (3.98e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (6.81e-5)" "unprognostic (2.26e-2)" "unprognostic (3.12e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-1)" 1236.3 1035.1 515.2 786.9 538.3 1743.3 1798.7 522.4 778.1 1690.1 510.7 1412.8 798.0 1295.2 1388.7 1185.6 1420.7 647.6 890.3 487.5 544.8 858.2 794.9 794.7 1435.7 527.8 511.9 3356.4 2236.0 695.4 869.5 736.1 541.3 1103.1 982.0 346.6 1189.5 847.1 1115.8 1320.8 960.1 962.1 549.0 899.0 1135.5 374.3 528.7 1351.4 1179.5 830.7 1438.8 1309.6 1274.2 552.5 2211.5 924.6 1611.4 1369.2 2045.7 4096.6 2577.6 1283.0 1703.7 1560.0 1108.9 2467.5 933.6 4112.3 2002.9 1451.6 1477.1 1370.3 1871.2 2405.7 1976.3 1314.2 2557.4 2142.3 1402.4 2303.5 2447.2 3322.0 864.6 3382.6 3711.3 1390.4 3027.2 2813.9 2191.6 2129.9 2706.3 2106.7 1814.5 1247.7 2665.7 3741.2 2497.9 1659.1 1724.1 2407.7 3118.5 2702.2 1912.0 1798.7 1367.2 1632.0 836.3 2298.6 3961.6 1316.4 1268.8 4480.6 1345.5 781.6 1429.6 1498.4 2357.4 1290.8 1314.5 2793.5 531.3 2814.4 544.2 234.9 665.6 101.3 758.7 619.1 1520.2 1320.3 1385.5 1151.0 1138.3 1105.7 1729.8 1570.9 56.7 1005.7 552.2 942.7 1140.0 2356.3 515.2 538.3 522.4 778.1 487.5 544.8 527.8 511.9 541.3 549.0 528.7 552.5 1586.8 653.9 1042.2 29.7 3056.7 2843.0 4383.1 2206.0 3168.8 339.6 3182.0 5498.6 375.2 1522.7 1266.7 412.0 89.6 2557.1 2009.8 595.2 1993.7 1697.1 1438.3 840.8 2334.8 1567.8 1236.6 1980.6 35.0 2708.5 4211.6 1464.3 978.1 1009.8 1041.9 2287.9 1546.3 1087.2 1452.5 146.4 33.8 1986.9 720.2 1758.7 2200.6 1189.4 2829.9 1536.8 1406.9 35.6 2171.5 806.3 1969.1 27.2 37.7 1851.6 1567.8 2156.4 2067.8 3935.4 1225.7 2454.6 571.0 298.8 1051.8 2546.2 2122.7 682.8 501.7 3198.9 2893.0 2613.1 2318.2 2797.0 2572.8 3991.1 RPN1 OST1 ENSG00000163902 "Ribophorin I" P04843 3 128619969-128681075 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 424.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009748, HPA026828, HPA051520" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 730000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" Cytosol "CAB009748: AB_2182230, HPA026828: AB_10610418, HPA051520: AB_2681521" "unprognostic (4.83e-2)" "unprognostic (5.92e-2)" "unprognostic (1.10e-1)" "unprognostic (7.67e-2)" "unprognostic (2.36e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.71e-1)" "unprognostic (2.43e-1)" "unprognostic (2.28e-2)" "unprognostic (4.58e-3)" "unprognostic (2.87e-1)" "unprognostic (7.68e-2)" "unprognostic (7.86e-2)" "unprognostic (1.52e-2)" "unprognostic (1.44e-1)" "unprognostic (9.74e-2)" 97.9 88.3 56.7 94.5 65.5 97.1 105.5 69.0 63.3 142.0 96.2 124.0 97.1 92.0 352.4 76.6 124.8 90.5 82.6 56.1 71.4 119.5 226.3 112.7 76.8 72.7 65.8 80.8 118.8 143.8 83.7 139.8 69.4 100.2 134.3 46.9 120.4 113.9 89.2 63.5 94.5 111.6 66.7 85.2 115.0 90.9 68.1 86.0 177.7 77.7 102.4 117.2 64.0 77.9 358.5 190.9 156.2 289.8 412.7 273.1 351.3 300.0 393.2 391.4 452.1 399.4 328.2 221.9 274.8 437.3 363.2 349.7 255.4 268.2 374.7 158.8 160.3 392.7 127.9 332.3 454.3 322.5 198.2 229.5 307.3 258.4 377.5 260.9 308.6 164.2 164.2 289.6 260.4 327.8 179.7 353.0 198.1 476.6 170.2 193.6 209.4 540.6 272.7 212.0 238.6 137.4 246.3 253.6 313.6 199.0 271.0 329.0 203.2 200.9 154.7 297.0 226.9 306.1 259.9 234.4 329.4 235.9 296.9 178.0 171.6 137.6 129.3 147.0 154.7 91.5 104.7 117.7 159.5 60.7 63.8 99.3 233.2 90.3 159.3 192.4 114.2 250.8 56.7 65.5 69.0 63.3 56.1 71.4 72.7 65.8 69.4 66.7 68.1 77.9 82.9 60.9 74.1 13.1 72.4 49.5 83.6 102.8 55.2 13.0 53.7 26.9 42.4 51.5 91.6 112.2 8.4 113.7 59.1 126.0 15.6 111.5 19.1 85.3 73.9 72.4 43.3 63.5 11.7 93.3 199.1 91.7 113.2 126.8 43.7 40.2 96.0 180.0 135.7 20.2 16.3 158.4 73.2 154.1 70.8 29.5 94.1 87.6 58.7 11.2 77.0 30.3 39.1 18.1 21.3 104.0 83.1 64.3 424.1 93.3 109.1 90.7 110.2 13.2 46.0 43.9 53.7 65.9 62.6 67.0 53.4 156.7 65.8 54.0 130.2 78.9 RPS15 "MGC111130, RIG, S15" ENSG00000115268 "Ribosomal protein S15" P62841 19 1438358-1440495 "Cancer-related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054510, HPA057793" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 460000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA054510: AB_2682510, HPA057793: AB_2683528" "unprognostic (4.47e-3)" "unprognostic (1.30e-1)" "unprognostic (6.58e-2)" "unprognostic (1.08e-3)" "unprognostic (5.98e-2)" "unprognostic (2.05e-1)" "unprognostic (4.33e-3)" "unprognostic (4.42e-2)" "unprognostic (2.58e-1)" "unprognostic (2.73e-2)" "unprognostic (3.28e-2)" "unprognostic (5.00e-2)" "unprognostic (1.44e-3)" "unprognostic (5.21e-2)" "unprognostic (5.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.61e-2)" 1492.7 1253.1 1112.3 594.4 1143.2 1201.0 1547.4 1088.6 1395.0 1699.5 1028.4 1466.7 565.2 1205.7 337.6 1872.1 1415.6 166.3 1222.6 1051.4 1084.5 1226.1 1106.2 1025.6 705.7 1119.1 1079.2 2717.3 2330.8 409.2 1315.7 346.3 1114.3 1664.9 298.2 234.6 1381.1 396.4 1841.8 2676.2 1250.1 283.0 1143.2 1523.9 1350.1 477.9 1143.5 649.3 1103.0 594.2 600.6 1316.7 1721.5 1162.3 1863.6 1949.4 837.1 1144.5 771.7 1118.2 1433.0 948.7 754.2 1116.7 871.3 3150.8 639.1 2285.2 829.1 618.8 394.6 1156.9 825.1 1177.6 426.5 1914.8 4301.3 748.4 1695.6 3041.6 811.7 1925.8 1374.1 1376.2 1406.1 757.0 737.2 1077.8 988.8 2049.0 1550.5 3197.1 703.7 3284.2 1608.3 2585.9 1887.0 1480.4 2481.0 1646.7 996.2 3053.8 1040.3 2026.5 1343.5 1589.3 801.9 1364.7 2927.8 442.0 1044.2 2555.0 1017.1 939.2 1077.7 1889.0 2131.4 2749.8 2994.2 2300.7 930.5 1737.0 1099.9 1348.7 2387.0 1017.0 2368.1 2005.8 3279.4 5335.9 3615.4 2988.4 3232.2 4867.3 4338.2 3612.2 457.2 2451.1 1592.7 2680.6 3662.4 7245.4 1112.3 1143.2 1088.6 1395.0 1051.4 1084.5 1119.1 1079.2 1114.3 1143.2 1143.5 1162.3 2203.3 910.2 1539.7 53.8 4976.8 9160.6 6537.1 4454.9 5021.3 436.1 7563.8 10700.9 365.8 2203.3 2335.6 1533.8 175.2 3985.2 3071.1 1757.4 3887.6 2275.1 984.8 1187.0 2584.3 2724.2 1811.8 2836.0 34.2 5298.7 6326.9 2621.6 1808.4 1631.3 1777.8 3650.4 3121.2 3161.6 3741.9 153.1 40.3 4148.0 1395.6 4863.0 7853.2 3297.3 3973.6 3101.3 4637.0 35.6 4562.7 1951.5 3042.3 20.1 73.6 3575.5 3343.2 2100.7 3087.8 6046.3 4380.3 5701.1 1076.4 622.3 1341.1 3160.4 2955.8 681.9 901.2 5781.9 12628.8 3849.3 4291.2 2492.1 4237.1 6173.2 RPS2 "LLREP3, S2" ENSG00000140988 "Ribosomal protein S2" P15880 16 1962058-1964841 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055133 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA 320000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA055133: AB_2682708" "unprognostic (2.98e-2)" "unprognostic (2.44e-1)" "unprognostic (8.43e-2)" "unprognostic (3.49e-2)" "unprognostic (4.15e-2)" "unprognostic (4.39e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (7.43e-2)" "unprognostic (3.17e-1)" "unprognostic (7.23e-2)" "unprognostic (2.00e-2)" "unprognostic (3.33e-1)" "prognostic unfavorable (3.04e-7)" "unprognostic (1.61e-1)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.47e-1)" 1690.3 1371.4 724.2 1077.5 741.5 2753.6 1803.0 715.7 944.0 1873.9 730.0 1509.2 957.5 1382.0 615.7 2558.8 1584.3 696.4 1237.7 712.7 742.4 1051.6 1423.2 1204.2 1914.1 797.8 741.9 3256.7 4556.8 388.1 972.5 832.6 777.7 1473.5 762.9 148.1 1477.9 636.9 2367.2 2781.5 1482.9 616.5 775.9 1849.7 1599.6 419.7 767.4 1570.4 1025.2 1558.8 1602.3 1750.8 1810.5 777.2 2258.0 3020.8 1716.3 5571.2 2433.0 5946.5 3093.8 1506.8 3381.7 3653.7 2581.3 5415.0 1451.8 4124.7 2329.8 2599.8 1226.5 2625.3 2553.6 4786.8 1372.0 2720.7 4959.5 1437.5 3382.8 4939.7 6019.8 3263.4 2174.4 8105.2 6715.4 3155.0 5057.6 3734.5 3606.2 3601.3 3014.4 2244.9 2591.9 9854.0 4110.2 5683.0 5591.7 2742.4 2706.1 4981.3 2846.5 4915.9 3411.9 1993.3 3154.5 2856.4 1465.0 4355.3 3538.6 1481.8 2933.7 5612.6 1757.9 1961.2 2605.3 499.3 3123.2 908.6 1554.7 5464.5 1056.9 2809.3 2532.6 74.1 438.2 239.9 562.4 545.5 932.7 1765.0 1096.6 864.3 805.8 1525.5 1366.1 1034.5 88.0 667.8 449.4 803.5 844.5 749.9 724.2 741.5 715.7 944.0 712.7 742.4 797.8 741.9 777.7 775.9 767.4 777.2 1261.2 519.2 1240.7 8.8 5674.4 11938.0 10835.5 3903.6 3510.9 362.3 12291.0 12660.6 252.4 2427.7 2182.1 910.4 187.7 8328.8 4158.8 1406.9 3212.6 4491.8 298.5 1154.3 4108.9 4082.2 2111.6 4032.5 13.2 11401.9 14898.5 2987.2 1703.4 1777.4 1021.9 4053.7 3477.4 2195.6 6029.4 277.6 15.7 4569.6 1627.6 5640.5 9869.6 489.7 4210.7 3709.4 5115.6 15.9 6772.9 965.3 3821.9 13.0 25.5 5585.7 2941.4 1575.6 3202.3 9790.4 2044.2 2439.2 906.1 477.8 1255.6 4193.6 3603.8 388.8 1997.9 5900.2 15069.3 8184.0 4718.2 6863.0 6345.9 11758.5 RPS3 "FLJ26283, FLJ27450, MGC87870, S3" ENSG00000149273 "Ribosomal protein S3" P23396 11 75399515-75422280 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Lyase, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA063339 Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA 560000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA063339: AB_2684990" "unprognostic (3.62e-2)" "unprognostic (6.94e-3)" "unprognostic (2.64e-1)" "unprognostic (1.44e-2)" "unprognostic (5.55e-2)" "unprognostic (1.08e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (2.69e-1)" "unprognostic (5.75e-2)" "unprognostic (3.27e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.92e-6)" "unprognostic (3.22e-1)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (2.19e-1)" 1139.4 747.7 431.1 955.9 446.8 2080.0 1950.0 427.3 575.6 1529.6 427.4 1220.4 946.0 1060.9 708.7 1669.8 1270.5 556.5 734.1 417.1 441.6 672.3 631.7 846.0 1663.4 446.6 430.8 2914.0 1761.9 356.4 660.5 760.6 442.8 929.1 919.3 352.7 1049.9 662.1 1125.5 1783.9 1128.2 739.8 444.4 1346.4 1082.2 287.7 435.1 1403.5 717.1 749.0 1360.4 1054.9 1384.5 446.9 1899.8 1145.7 1595.6 1767.5 1970.0 3482.1 2060.8 1763.7 2256.3 2289.4 1481.2 3331.6 2196.8 6547.1 2108.6 1598.8 1261.5 2672.3 2085.6 3290.7 2093.8 1749.1 1618.9 2688.6 1042.6 1490.2 2931.1 4398.6 1690.0 4124.1 4397.7 1568.8 4323.1 2684.0 3055.0 2876.5 2736.9 1809.7 2089.7 2071.2 2660.9 2112.4 2007.4 6591.3 1342.5 2482.3 5580.2 4834.0 2275.9 1551.8 1366.7 1933.6 1299.3 3050.2 1897.1 1535.9 3123.3 3289.9 2470.7 1099.6 1822.9 1515.3 1627.3 1647.2 2198.0 7283.3 660.4 2409.4 1138.1 430.3 770.8 245.5 1405.7 515.5 1924.9 1602.2 1823.1 1489.0 1099.3 1454.0 2102.1 1633.9 174.3 1142.6 512.4 960.4 1283.7 4244.2 431.1 446.8 427.3 575.6 417.1 441.6 446.6 430.8 442.8 444.4 435.1 446.9 1993.9 932.7 1604.3 18.6 4790.5 6297.7 7369.7 5554.5 4497.7 423.9 6945.0 9521.7 418.9 2088.9 2555.7 726.4 133.5 6188.6 4009.1 1694.4 2183.4 2376.0 430.9 939.2 3054.9 2780.8 2067.1 3428.9 28.3 5373.2 9079.0 2364.6 1651.9 1363.9 1641.6 4246.7 2916.7 1369.0 3662.5 132.9 32.6 4425.4 1621.5 3089.2 4666.7 968.5 3755.0 2393.1 2835.3 38.4 3626.4 957.1 4120.5 19.6 47.5 3805.0 3535.7 1803.2 2848.0 5827.8 2969.4 2226.4 797.6 505.5 1117.5 3204.8 3221.9 449.3 618.6 5734.6 7842.8 5867.5 4904.4 4865.2 5657.1 7206.9 RPS6KA1 "HU-1, MAPKAPK1, p90Rsk, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.1;monocytes: 81.2;NK-cells: 88.6;Proximal enterocytes: 93.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 77.6;U-937: 86.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol Nucleoplasm "CAB003852: AB_289590, HPA007981: AB_1079850" "unprognostic (1.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-3)" "prognostic favorable (7.20e-7)" "unprognostic (7.35e-2)" "unprognostic (3.69e-1)" "unprognostic (6.93e-3)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.84e-4)" "prognostic favorable (4.58e-4)" "unprognostic (4.77e-2)" "unprognostic (7.61e-2)" "prognostic favorable (8.33e-4)" 7.4 17.0 7.8 17.5 9.1 23.8 8.3 9.2 9.3 6.0 11.2 37.9 33.1 3.0 1.2 16.9 7.9 5.5 3.8 7.9 9.1 26.2 10.5 33.7 20.2 10.8 9.5 1.9 19.4 12.5 13.4 4.0 10.1 17.2 20.7 1.4 21.5 4.5 1.7 17.8 51.4 3.6 9.4 47.1 20.6 5.4 10.4 11.4 24.5 1.9 20.7 9.0 9.6 11.6 27.1 9.3 7.5 9.9 0.4 0.1 9.9 2.2 4.2 11.0 10.6 10.8 21.9 50.2 11.9 1.3 13.3 31.0 16.9 61.0 7.8 41.8 11.0 55.3 21.6 19.5 3.4 65.8 77.6 1.8 22.1 10.1 18.0 5.0 4.9 19.7 9.6 17.7 0.6 15.0 2.4 64.3 19.1 52.2 29.2 34.8 9.5 22.0 31.7 7.3 10.7 4.4 18.7 17.5 8.4 7.8 11.2 55.5 3.2 0.5 13.9 1.8 9.2 10.9 14.0 27.5 6.5 86.8 10.8 37.6 57.9 131.2 24.2 52.1 20.3 14.2 17.9 21.6 68.8 15.7 11.3 15.8 108.2 26.4 58.4 26.9 19.0 65.2 7.8 9.1 9.2 9.3 7.9 9.1 10.8 9.5 10.1 9.4 10.4 11.6 2.8 16.0 25.0 0.0 23.7 18.6 8.1 19.9 16.5 1.5 12.0 10.4 1.3 11.5 7.7 9.2 4.2 1.6 53.9 91.1 7.9 16.3 1.9 19.9 2.2 6.9 16.3 29.5 1.4 18.7 17.5 1.8 18.3 20.7 31.8 3.3 7.9 3.4 47.5 0.0 2.6 41.6 12.2 53.0 14.2 1.4 0.0 44.1 1.8 12.2 81.2 0.6 88.6 1.0 12.3 28.1 41.9 0.0 14.2 18.8 93.3 17.2 13.6 1.8 6.6 0.8 2.7 1.6 3.4 10.9 11.6 4.1 36.3 2.0 43.6 9.1 RPS6KA3 "CLS, HU-3, MRX19, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 236.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytosol" "CAB003853: AB_562343, CAB013520: AB_2533378, HPA003221: AB_1853553" "unprognostic (1.87e-2)" "unprognostic (1.03e-1)" "unprognostic (1.80e-2)" "unprognostic (4.26e-2)" "unprognostic (3.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-3)" "unprognostic (1.02e-1)" "unprognostic (1.57e-1)" "unprognostic (5.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (4.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.09e-1)" "unprognostic (2.22e-1)" 21.1 18.8 6.9 33.7 10.2 16.2 14.8 12.7 12.8 16.1 8.5 32.8 24.1 17.5 8.5 18.7 15.1 26.9 21.1 8.7 9.4 19.5 45.0 32.3 31.3 8.4 10.0 10.6 17.2 59.4 5.9 19.5 8.5 19.9 31.8 15.7 13.2 18.0 51.8 15.0 27.6 27.8 8.7 29.2 21.1 5.5 10.6 32.9 21.2 40.3 32.6 34.2 8.5 8.0 44.9 77.0 28.4 14.8 27.1 47.3 8.6 38.0 57.4 27.8 37.7 87.7 56.2 29.3 12.8 40.0 40.5 30.9 32.8 32.2 51.1 24.8 26.1 34.6 46.2 236.8 27.7 67.8 34.2 30.3 25.1 43.5 54.4 24.3 101.9 30.4 23.1 81.0 29.4 21.2 44.2 20.7 20.6 57.8 45.9 23.3 60.0 33.8 23.9 36.9 13.1 12.8 51.1 15.3 54.4 35.3 0.1 20.0 57.3 30.1 20.8 96.3 21.7 64.3 42.1 32.1 56.9 33.1 72.6 11.9 3.8 7.9 4.7 5.3 8.3 2.4 5.4 5.2 5.6 3.2 3.7 4.5 5.8 6.6 6.0 6.7 2.9 2.2 6.9 10.2 12.7 12.8 8.7 9.4 8.4 10.0 8.5 8.7 10.6 8.0 60.6 44.8 67.5 31.6 34.8 54.4 37.0 21.2 10.2 37.8 20.4 10.8 22.9 34.3 41.1 16.5 22.9 4.0 70.0 63.5 3.9 26.3 0.4 10.8 24.0 61.1 25.0 19.1 142.2 30.5 6.7 31.6 24.5 26.1 44.3 8.3 34.6 65.4 22.6 13.5 108.4 59.1 28.5 40.8 104.3 1.5 13.1 62.6 37.4 126.5 53.7 27.5 46.4 116.6 27.0 37.4 57.9 21.1 25.5 56.6 33.5 25.1 23.3 9.7 19.7 41.5 21.3 6.4 8.7 13.8 55.5 3.6 66.0 14.2 61.1 63.8 RSBN1L "FLJ42526, FLJ45813, MGC71764" ENSG00000187257 "Round spermatid basic protein 1 like" Q6PCB5 7 77696459-77783022 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 349.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 60.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020406, HPA020413" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane" "HPA020406: AB_1856488, HPA020413: AB_2253910" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.72e-1)" "unprognostic (1.34e-1)" "unprognostic (3.62e-2)" "unprognostic (2.43e-2)" "prognostic favorable (3.74e-4)" "unprognostic (1.27e-2)" "unprognostic (3.78e-2)" "unprognostic (1.25e-1)" "unprognostic (9.02e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-3)" "unprognostic (1.53e-3)" 7.3 6.4 8.7 11.5 9.1 8.2 12.1 19.0 12.1 10.3 10.2 11.3 9.0 12.5 10.3 10.8 9.5 7.3 5.6 8.5 10.5 9.1 11.3 10.5 16.1 8.2 9.0 14.5 11.2 10.3 6.9 9.9 8.6 10.3 11.7 30.2 9.6 11.4 8.2 7.8 10.4 11.0 9.0 15.0 11.0 26.3 8.6 18.3 16.5 7.6 15.0 9.6 8.2 11.6 15.8 11.9 19.6 34.5 13.4 17.0 9.5 11.5 12.4 16.0 18.2 14.9 27.6 32.4 4.4 12.0 20.2 13.4 26.8 15.0 22.8 17.7 14.4 25.8 18.4 14.7 11.3 32.1 23.3 12.2 10.7 14.7 16.0 12.1 13.5 21.2 35.7 33.0 16.8 18.2 27.7 32.1 14.0 20.3 10.6 28.3 19.6 34.2 10.0 20.5 22.9 24.0 17.5 31.4 12.6 19.9 19.2 16.9 12.9 23.9 21.9 14.5 17.7 14.7 16.7 51.6 11.4 29.2 16.0 21.6 7.4 13.5 9.5 5.8 7.3 11.0 8.4 7.1 4.4 13.5 7.8 8.6 60.6 6.4 6.7 13.9 9.3 2.6 8.7 9.1 19.0 12.1 8.5 10.5 8.2 9.0 8.6 9.0 8.6 11.6 53.6 57.7 60.3 27.1 85.0 78.8 102.1 76.1 88.8 246.8 52.1 57.3 22.1 61.5 84.4 55.2 235.6 52.7 101.5 77.1 39.2 38.1 271.3 55.5 63.3 60.8 77.5 47.7 44.3 50.4 34.1 55.6 51.5 45.6 70.3 51.3 49.2 56.5 43.7 158.2 47.5 104.6 57.0 48.1 69.0 85.2 101.5 46.4 64.0 34.7 59.0 83.2 132.8 53.8 50.1 35.1 62.7 119.6 74.6 56.7 49.6 28.4 72.0 349.9 72.3 44.2 73.0 108.0 156.7 56.2 75.3 38.7 90.2 61.7 79.1 84.0 RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 75.3;Inhibitory neurons: 86.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;U-266/70: 4.2" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" 0.2 0.0 2.8 0.7 4.4 0.1 0.0 1.3 16.2 3.4 2.6 13.9 3.4 0.0 1.7 5.9 0.0 3.2 0.2 6.6 13.2 0.0 0.4 7.1 0.0 2.6 23.0 0.3 0.0 0.0 2.9 17.3 2.0 8.7 7.8 0.3 0.0 2.3 0.0 0.0 4.6 0.3 2.1 0.0 7.6 0.7 3.5 0.0 0.0 0.0 0.0 1.7 0.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.4 1.3 16.2 6.6 13.2 2.6 23.0 2.0 2.1 3.5 6.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.3 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 86.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 4.7 0.0 0.0 0.0 4.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.7 0.0 0.0 1.0 0.0 0.2 0.0 0.0 RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 51.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 18.5;Endothelial cells: 42.4;Fibroblasts: 73.0;Hepatic stellate cells: 26.4;Inhibitory neurons: 17.8;Leydig cells: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 21.9;BJ hTERT+: 3.6;hTERT-RPE1: 6.3;U-138 MG: 4.6;U-87 MG: 4.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 21.2" HPA029957 Uncertain "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 33: Fibroblasts - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" 30.9 15.1 2.1 16.1 2.4 0.0 12.4 3.3 4.9 13.8 0.0 7.4 2.2 51.4 28.4 5.4 25.3 11.1 0.9 8.5 1.5 4.0 6.5 5.1 3.7 1.6 1.4 3.6 1.6 0.1 3.1 35.4 0.3 6.3 6.6 0.1 5.4 20.0 39.8 2.8 10.3 48.1 0.0 1.8 13.3 1.0 1.0 2.4 3.6 5.0 1.4 8.6 7.1 0.9 0.0 21.9 0.0 0.0 1.0 0.0 0.0 0.0 3.6 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 6.3 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 4.6 1.8 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 3.3 4.9 8.5 1.5 1.6 1.4 0.3 0.0 1.0 0.9 3.6 0.0 0.0 0.7 0.1 0.9 0.1 0.0 0.6 1.5 0.2 0.9 0.5 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.4 12.3 0.3 18.5 42.4 0.0 0.0 5.9 0.0 1.1 73.0 5.1 0.3 0.0 0.0 26.4 0.4 1.6 0.0 17.8 0.0 0.0 1.0 0.8 2.2 27.4 0.4 1.8 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.2 6.6 2.1 3.5 0.1 0.4 0.4 0.1 1.6 0.1 0.1 0.0 0.2 RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 175.5;Glandular and luminal cells: 155.8;Microglial cells: 195.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 23.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 251.3;HMC-1: 145.3;JURKAT: 226.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: AB_2675733" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" 14.8 3.8 2.9 20.3 2.1 45.5 27.1 2.6 4.0 15.3 5.1 6.7 5.1 3.3 3.1 9.2 4.7 16.0 6.3 2.8 3.2 4.6 7.0 22.4 11.3 6.0 4.3 6.3 4.0 1.5 5.1 8.5 6.5 13.5 6.5 0.3 39.2 3.5 18.9 11.6 6.8 9.2 4.9 10.2 16.9 3.8 9.1 28.2 4.8 1.4 9.9 20.8 12.8 7.9 50.9 3.8 0.1 0.3 12.5 16.0 32.0 28.1 28.4 15.3 11.6 2.5 37.7 24.9 1.8 24.9 25.5 45.0 3.0 33.6 21.4 38.7 3.8 251.3 10.1 11.6 22.9 29.4 145.3 30.9 19.8 46.6 45.6 21.2 8.8 226.3 17.3 14.1 32.7 10.7 119.3 46.5 2.2 27.4 14.5 119.2 84.6 15.3 20.7 19.9 1.4 0.0 28.9 7.2 10.5 6.8 14.7 67.8 37.0 25.1 32.4 37.8 42.8 46.4 20.7 23.3 31.2 63.4 37.4 23.9 3.1 7.1 3.4 1.4 3.2 4.1 3.0 3.2 0.9 3.6 4.5 3.7 3.4 1.5 4.7 3.4 4.5 2.2 2.9 2.1 2.6 4.0 2.8 3.2 6.0 4.3 6.5 4.9 9.1 7.9 6.2 54.5 35.4 1.6 27.0 41.6 52.7 61.2 54.7 2.3 175.5 94.6 3.2 28.6 60.8 20.2 0.0 2.1 39.5 18.7 1.9 39.7 19.4 89.6 21.5 9.2 6.0 47.3 3.5 28.1 21.4 49.2 84.6 155.8 17.7 29.2 4.6 5.4 68.4 0.0 3.2 12.4 28.5 77.0 122.5 27.1 4.7 84.4 28.4 195.8 42.2 0.5 39.1 1.5 1.6 101.0 15.8 4.5 27.7 43.6 8.3 1.6 78.6 0.8 0.0 111.3 51.2 29.0 28.0 53.7 20.2 2.5 41.6 2.7 17.0 75.3 RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 196.9;Hepatic stellate cells: 124.2;Inhibitory neurons: 326.3;Oligodendrocyte precursor cells: 262.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 19.6;fHDF/TERT166: 16.5;HEL: 35.9;HSkMC: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" 7.0 2.8 9.4 2.1 13.2 0.2 5.1 93.1 8.7 8.4 0.0 6.5 1.2 7.4 3.6 2.5 4.7 5.0 8.2 13.1 2.3 1.4 0.6 3.8 1.3 1.4 12.8 4.7 1.0 1.0 3.0 5.8 4.6 2.5 2.4 5.2 3.1 2.4 3.9 2.4 2.5 6.5 4.2 1.9 2.7 3.6 3.6 0.5 3.7 4.8 1.1 3.8 3.9 1.2 0.0 0.0 0.4 1.9 5.0 7.2 0.0 7.6 11.6 5.0 7.6 0.0 0.0 19.6 0.0 16.5 0.0 0.0 4.0 0.5 3.3 0.0 3.2 35.9 0.0 0.0 1.9 0.0 0.0 13.6 0.0 8.4 0.4 0.0 10.8 0.0 0.1 0.0 1.3 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 6.0 0.0 0.0 0.0 7.8 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.8 0.0 6.3 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 13.2 93.1 8.7 13.1 2.3 1.4 12.8 4.6 4.2 3.6 1.2 44.9 0.0 1.1 90.8 0.1 6.2 0.2 0.0 0.6 142.1 1.2 5.1 46.0 0.0 0.6 0.0 16.7 1.1 0.5 0.2 1.9 0.0 2.6 1.1 65.8 64.3 47.7 2.7 196.9 0.2 0.3 77.7 0.5 1.1 1.3 2.1 124.2 1.5 1.9 35.3 326.3 0.6 0.0 4.1 9.4 7.5 96.3 1.2 10.6 103.0 0.0 3.9 0.0 262.4 17.3 0.2 0.0 98.9 0.0 0.3 0.0 0.1 0.0 7.2 65.7 24.4 43.1 3.3 16.8 0.9 4.8 1.1 1.1 20.7 0.0 0.1 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 218.9;Kupffer cells: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.5" "Group enriched" "Detected in many" 5 "granulocytes: 19.5;monocytes: 12.9" "Cell line enhanced" "Detected in many" "HaCaT: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 40.5 22.7 33.5 14.5 36.4 18.9 11.2 25.5 29.4 12.2 16.9 16.6 25.8 13.5 8.7 28.5 16.5 13.6 19.4 27.1 30.2 16.0 32.9 18.8 8.2 32.9 31.3 21.7 25.4 45.1 3.5 14.5 30.8 15.6 10.0 5.4 21.7 17.1 106.5 88.1 28.0 11.1 30.4 25.1 14.7 7.9 42.7 6.0 17.6 51.9 7.6 16.2 8.2 22.6 19.6 36.4 14.7 21.9 42.8 19.1 66.7 14.1 16.1 9.6 6.5 20.7 28.0 0.0 25.8 22.5 15.1 105.5 7.7 32.8 2.9 26.3 7.2 0.1 47.5 30.0 20.4 18.8 4.8 29.0 52.1 11.5 10.6 12.9 12.8 1.6 26.0 1.1 8.7 61.8 1.1 59.5 17.5 63.4 16.9 7.4 30.3 36.7 12.2 64.3 17.2 10.5 37.3 46.9 10.6 7.1 44.9 78.8 16.5 16.2 23.4 17.4 9.7 1.7 0.2 0.4 11.6 33.9 12.7 1.3 8.1 6.6 1.4 12.9 0.2 0.3 0.9 1.0 3.2 0.1 0.2 1.2 19.5 2.2 11.2 0.7 1.2 3.2 33.5 36.4 25.5 29.4 27.1 30.2 32.9 31.3 30.8 30.4 42.7 22.6 32.1 32.1 22.9 36.2 4.6 34.5 16.5 21.1 12.5 6.0 16.7 14.4 38.8 72.9 26.2 9.2 25.0 30.1 11.0 72.3 1.9 13.9 4.3 19.8 16.6 28.9 9.6 30.9 9.1 14.1 29.5 23.7 17.9 17.4 1.3 21.3 71.0 218.9 31.9 33.7 17.6 21.2 10.2 134.2 30.0 18.8 32.3 50.4 12.4 10.3 80.4 36.5 14.4 29.1 6.0 15.9 32.4 21.1 7.4 17.7 55.6 19.9 34.4 19.9 19.7 34.6 30.6 0.9 9.4 34.4 46.9 23.9 12.6 15.5 27.5 32.8 RXRB "H-2RIIBP, NR2B2, RCoR-1" ENSG00000204231 "Retinoid X receptor beta" P28702 6 33193588-33200665 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.0;RH-30: 14.4;RT4: 12.1;T-47d: 16.1;U-266/70: 11.1;U-266/84: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002003, HPA063653" Supported Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB002003: , HPA063653: AB_2685076" "unprognostic (3.51e-1)" "unprognostic (8.46e-2)" "unprognostic (1.94e-1)" "unprognostic (2.22e-2)" "unprognostic (2.00e-2)" "unprognostic (4.71e-3)" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.67e-3)" "unprognostic (8.13e-3)" "unprognostic (9.53e-3)" "unprognostic (8.30e-2)" "unprognostic (1.55e-1)" "unprognostic (6.38e-2)" "unprognostic (8.53e-3)" 26.8 29.1 1.5 2.0 1.5 2.3 27.1 1.6 5.7 33.9 1.4 34.4 3.9 31.9 7.4 27.0 31.4 3.3 31.4 1.5 2.6 29.5 34.4 27.2 1.4 1.5 1.7 32.9 32.3 0.0 33.0 2.5 1.5 32.8 1.6 3.2 27.0 3.3 42.5 26.3 28.6 9.6 1.6 38.3 28.3 20.0 1.6 2.8 37.7 12.3 9.1 30.6 29.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 10.0 0.0 10.4 7.1 0.0 11.0 4.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 8.9 0.0 0.0 0.5 3.2 0.0 0.0 0.1 14.4 0.0 8.0 12.1 0.0 7.4 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 4.8 0.0 0.0 11.1 11.8 9.2 0.0 0.0 0.0 2.3 0.4 1.7 1.1 0.3 0.8 1.0 1.3 1.3 0.6 0.3 1.1 0.8 0.7 0.8 0.6 0.6 1.1 0.3 1.5 1.5 1.6 5.7 1.5 2.6 1.5 1.7 1.5 1.6 1.6 1.7 21.2 41.7 13.3 14.4 19.2 17.3 14.9 8.9 18.2 25.2 22.4 18.9 16.1 15.7 14.7 5.5 20.9 23.6 26.3 21.8 25.4 19.9 2.7 10.6 14.7 18.2 22.0 8.6 14.9 16.2 17.9 18.3 23.0 11.9 10.2 22.5 14.3 15.9 15.8 18.5 12.9 21.8 16.2 14.7 9.2 8.6 16.1 12.2 16.0 10.3 18.8 16.6 33.0 14.1 15.2 13.6 20.2 16.1 12.0 16.3 23.2 14.1 10.8 20.4 26.3 19.3 20.0 17.7 12.5 16.8 18.8 28.7 19.4 18.7 24.5 12.7 RXRG NR2B3 ENSG00000143171 "Retinoid X receptor gamma" P48443 1 165400922-165445355 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;pituitary gland: 29.9;retina: 24.3;skeletal muscle: 49.7" "Group enriched" "Detected in some" 4 "Astrocytes: 13.4;Cone photoreceptor cells: 25.0;Melanocytes: 28.4;Muller glia cells: 16.8;Sertoli cells: 13.1;Skeletal myocytes: 35.9" "Group enriched" "Detected in many" 13 "melanoma: 25.7;thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 39.4" "Region enriched" "Detected in many" 5 "basal ganglia: 100.2" "Low region specificity" "Detected in many" "CAB002615, HPA012933" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB002615: , HPA012933: AB_2732406" "unprognostic (2.29e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.66e-1)" "unprognostic (4.29e-2)" "unprognostic (6.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.13e-2)" "unprognostic (6.86e-2)" "unprognostic (2.95e-2)" "unprognostic (5.41e-3)" "unprognostic (2.52e-2)" "unprognostic (6.12e-3)" "unprognostic (1.18e-1)" "prognostic favorable (9.40e-5)" "unprognostic (5.03e-2)" 2.4 3.2 14.6 0.4 16.6 0.0 1.0 11.7 17.4 3.0 11.7 4.1 0.7 1.1 0.7 1.0 2.8 0.6 5.3 12.4 21.5 0.2 0.3 2.8 0.3 25.6 14.8 1.0 2.1 0.1 29.9 0.7 22.2 1.1 2.0 24.3 1.2 1.4 49.7 2.3 1.6 1.2 13.6 0.4 1.4 1.0 32.1 0.1 0.7 7.6 0.0 1.6 2.1 15.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 39.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 16.6 11.7 17.4 12.4 21.5 25.6 14.8 22.2 13.6 32.1 15.6 0.9 0.0 0.0 13.4 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 2.8 5.0 0.0 28.4 0.0 0.0 16.8 0.0 1.0 1.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.5 13.1 35.9 3.4 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 S100A1 "S100-alpha, S100A" ENSG00000160678 "S100 calcium binding protein A1" P23297 1 153627926-153632039 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 3076.8;skeletal muscle: 3060.2;tongue: 4911.5" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 1848.3" "Group enriched" "Detected in all" 5 "melanoma: 210.5;ovarian cancer: 110.1;thyroid cancer: 123.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Hep G2: 325.8;SK-MEL-30: 1130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002599, HPA006462" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 290000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nucleoplasm, Golgi apparatus" "CAB002599: AB_2315307, HPA006462: AB_1079857" "unprognostic (6.13e-2)" "unprognostic (7.60e-2)" "unprognostic (5.96e-5)" "prognostic unfavorable (1.12e-4)" "unprognostic (1.19e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (2.34e-3)" "unprognostic (6.83e-3)" "unprognostic (5.22e-1)" "unprognostic (5.04e-3)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.68e-1)" "unprognostic (4.56e-2)" "unprognostic (2.70e-3)" "unprognostic (9.74e-4)" 179.7 8.3 811.3 6.5 898.6 2.3 77.2 851.4 952.4 2.9 643.9 14.5 11.1 4.2 1.0 81.0 41.8 4.9 3076.8 779.4 813.6 194.9 4.5 3.9 5.1 907.6 894.8 2.0 16.8 160.9 54.6 18.1 871.2 29.0 1.2 36.5 622.1 9.3 3060.2 23.0 6.9 1.6 847.7 4.2 23.1 5.9 882.9 9.4 167.9 4911.5 4.0 4.3 2.9 967.6 6.0 3.4 3.9 33.7 0.5 0.2 2.9 7.7 0.2 0.6 0.2 6.6 3.4 3.7 137.7 0.6 2.7 10.3 0.3 0.4 0.0 4.2 3.3 8.2 5.4 325.8 0.4 3.0 2.3 0.7 0.0 0.0 0.1 7.9 0.0 1.5 27.2 3.7 0.1 10.6 1.2 4.9 1.8 4.3 2.6 22.5 3.3 8.0 6.0 12.1 6.1 1.9 3.5 10.6 1130.2 11.1 32.8 16.2 2.7 3.3 2.8 3.0 3.8 6.1 5.7 6.2 2.5 6.2 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 811.3 898.6 851.4 952.4 779.4 813.6 907.6 894.8 871.2 847.7 882.9 967.6 4.3 0.0 0.0 59.4 9.5 9.7 1.2 0.4 1.8 1.1 369.9 354.1 74.4 8.6 0.2 154.5 2.1 1.1 5.9 1.1 162.4 0.9 0.6 90.5 17.3 5.3 1.8 0.0 0.3 3.7 1.9 6.0 0.0 193.3 0.0 0.0 7.9 4.7 199.1 0.0 0.3 3.7 0.0 0.6 3.5 2.2 6.5 15.6 341.5 2.8 0.0 163.5 0.0 2.0 45.8 1.9 0.6 9.1 0.0 1.8 0.9 1848.3 0.2 2.7 0.0 67.0 4.2 3.8 2.8 1.0 2.3 3.4 8.2 2.3 1.8 0.7 S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3574.5;kidney: 1380.0;urinary bladder: 1097.4" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 11464.4;Basal prostatic cells: 4796.7;Basal respiratory cells: 10600.9;Basal squamous epithelial cells: 4741.9;Club cells: 3331.1;Prostatic glandular cells: 9446.4;Squamous epithelial cells: 9013.7;Suprabasal keratinocytes: 3626.5;Urothelial cells: 5382.7" "Cancer enhanced" "Detected in all" "cervical cancer: 848.8;head and neck cancer: 1229.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.1" "Group enriched" "Detected in many" 5 "HBEC3-KT: 21286.9;RT4: 8382.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 27000 "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: AB_2684767" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (1.57e-2)" "unprognostic (1.42e-3)" "unprognostic (1.98e-1)" "unprognostic (3.20e-1)" "unprognostic (4.21e-4)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.52e-2)" "unprognostic (8.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" 4.0 2.1 2.5 4.1 2.7 1.0 17.3 2.4 3.6 279.9 2.0 3.1 0.8 2.5 16.1 3574.5 5.6 1.8 3.9 2.3 3.2 1380.0 1.7 12.0 0.5 4.1 3.0 1.9 2.1 0.1 5.4 0.8 3.0 48.1 1.6 0.4 377.1 16.9 3.3 429.6 1.6 1.9 3.0 1.5 3.6 2.8 3.4 6.3 11.9 1.4 416.1 1097.4 747.3 3.5 827.0 9.3 1.1 0.9 10.8 4.2 1.2 10.4 11.5 9.0 7.8 2.1 26.8 1.2 418.3 17.8 18.3 2001.4 1.3 21286.9 9.9 5.4 3.7 3.8 56.2 5.0 4.5 0.7 1.9 8.8 2777.8 24.1 3135.5 21.7 13.2 0.0 0.8 1.5 47.7 3.4 0.2 0.2 2.2 22.3 155.4 1.3 497.9 2.1 502.4 8382.8 16.5 0.5 34.9 5.8 9.0 5.9 3.2 5.7 6.0 12.5 692.6 92.4 280.6 1.9 2.4 4.7 26.5 1.8 24.2 10.1 0.4 0.0 2.3 0.0 1.4 0.4 1.6 1.3 0.3 0.0 0.4 0.3 4.3 0.0 0.5 2.2 1.6 0.7 2.5 2.7 2.4 3.6 2.3 3.2 4.1 3.0 3.0 3.0 3.4 3.5 1.4 9.6 17.3 2.6 1.0 11464.4 4796.7 10600.9 4741.9 0.0 22.2 35.4 2.9 1.5 3331.1 218.8 0.0 0.7 0.8 3.2 1226.7 24.8 4.5 16.3 2.5 108.2 1.8 3.0 0.1 27.6 1.0 130.8 1.5 24.5 17.1 1.2 0.4 0.1 1.8 0.0 0.0 1.6 789.4 0.8 676.4 8.1 0.6 18.0 759.5 0.0 5.3 1.1 0.0 2.0 0.1 668.7 2.5 0.7 25.9 9446.4 0.8 11.8 560.8 0.1 0.0 5.5 207.0 0.6 3.0 9013.7 3626.5 0.3 37.8 8.9 2.0 5382.7 S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 2708.8;Langerhans cells: 5952.7;Macrophages: 2786.0;monocytes: 3172.6;NK-cells: 2130.8;Skeletal myocytes: 2034.0;T-cells: 2111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 2614.3;ASC diff: 3300.1;BJ hTERT+: 6738.6;fHDF/TERT166: 4819.1;RPMI-8226: 2700.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.6" "CAB002618, HPA007486, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 9600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007486: , HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" 982.3 77.1 25.5 353.9 26.2 1090.8 561.9 27.5 53.1 566.3 32.0 301.7 91.7 177.8 124.5 224.0 217.6 167.6 268.5 24.7 27.4 247.0 64.3 874.2 221.0 31.7 26.4 51.0 53.8 18.1 24.8 182.9 29.8 223.7 331.5 10.0 245.4 155.8 163.0 371.5 234.3 297.7 27.8 443.0 133.3 32.2 33.7 112.6 191.9 424.6 315.4 391.6 455.2 34.1 11.8 2614.3 13.2 77.0 3300.1 2410.9 3.7 1664.4 6738.6 32.1 148.4 20.0 180.3 0.8 299.7 4819.1 3.5 65.3 8.8 20.9 23.6 405.2 2.3 1186.8 529.0 59.4 4.3 106.9 1924.6 364.2 21.5 62.2 13.0 4.9 2.6 0.7 9.9 4.2 2468.1 10.6 3.8 1273.9 7.2 189.7 1050.4 64.1 3.7 2700.2 103.5 71.3 108.5 11.6 24.9 1286.6 9.4 412.5 77.1 1493.7 3.1 8.5 13.7 2159.5 9.3 82.8 647.5 14.3 6.1 1367.9 127.2 2789.7 13536.2 1408.0 5800.5 9099.6 6077.0 761.6 5167.7 4700.0 9268.4 282.5 882.4 2641.3 12129.7 837.1 11862.4 1626.0 7406.7 24075.8 25.5 26.2 27.5 53.1 24.7 27.4 31.7 26.4 29.8 27.8 33.7 34.1 226.0 490.4 398.4 0.0 266.1 772.9 19.5 159.0 93.9 0.7 44.9 65.9 14.9 35.8 273.8 893.8 0.0 52.4 1345.4 8.9 111.6 21.9 7.3 53.0 473.0 209.1 4.8 730.9 0.0 23.5 255.5 1378.8 54.0 41.9 1395.8 0.6 96.4 18.6 1966.1 45.4 0.0 10.0 345.8 2708.8 5952.7 24.0 235.8 2786.0 1193.5 12.2 3172.6 3.6 2130.8 0.0 0.1 35.7 17.0 45.9 266.5 12.9 3.2 19.7 154.9 2.3 151.2 2034.0 1309.6 1.9 5.5 77.6 694.0 53.4 2111.1 32.5 11.3 73.1 S100A6 "2A9, CABP, CACY, PRA" ENSG00000197956 "S100 calcium binding protein A6" P06703 1 153534599-153536244 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 37545.1;Urothelial cells: 17431.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 17071.6;RPTEC TERT1: 20988.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002601, HPA007575, CAB040549, CAB047354" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 7000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "CAB002601: , CAB040549: , CAB047354: , HPA007575: AB_1079859" "unprognostic (8.80e-3)" "unprognostic (6.96e-2)" "unprognostic (2.31e-1)" "unprognostic (2.47e-2)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (1.27e-1)" "unprognostic (3.51e-1)" "unprognostic (6.86e-3)" "unprognostic (1.66e-1)" "unprognostic (3.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.88e-1)" "unprognostic (1.46e-2)" "prognostic favorable (7.56e-4)" 1873.9 666.6 435.5 1129.7 452.5 2003.6 1499.2 456.2 549.9 2306.1 425.9 2872.2 1504.1 1058.4 404.8 1300.4 879.9 1485.5 1046.0 425.8 593.7 2326.6 91.9 2216.9 365.1 520.2 488.9 556.8 204.2 68.4 311.2 709.2 489.1 827.7 2252.2 36.6 1123.5 1169.3 478.1 858.6 1367.0 965.1 488.8 519.1 1586.3 170.1 573.3 191.6 970.0 1010.8 504.8 3867.5 1276.0 530.4 3666.6 4412.8 4.3 330.6 7597.2 10482.0 9.3 4560.1 13403.9 2582.7 3352.7 273.3 8022.5 4.5 1319.7 7774.8 2078.7 1589.3 80.7 7340.5 1322.0 1340.0 1.6 731.2 2579.1 255.8 2730.2 28.1 458.7 4550.0 6406.8 2638.7 4734.2 3259.1 6078.3 0.7 3.2 12.3 7052.7 589.4 11.4 292.3 9.6 17071.6 7563.4 5.5 463.0 1250.1 20988.4 3918.8 1019.8 142.6 6251.9 6380.9 4628.4 3.7 835.3 1095.9 7473.3 2228.2 489.8 4463.8 7452.6 8.8 11.9 15.5 8619.0 728.4 4773.0 5517.3 6053.2 2413.8 1806.1 3258.0 1983.1 937.8 1664.9 1773.1 4240.8 583.7 1037.2 1378.3 9637.7 297.4 3066.5 2145.0 2217.6 8320.4 435.5 452.5 456.2 549.9 425.8 593.7 520.2 488.9 489.1 488.8 573.3 530.4 1177.8 4708.3 2663.1 17.6 343.0 1488.3 6868.7 7856.4 2416.5 4.9 1494.4 1445.2 326.6 1474.1 7013.9 8165.9 0.0 1368.2 999.9 8832.0 7446.5 6206.3 21.3 1148.6 3473.2 1801.5 2035.6 637.5 14.7 9903.1 2440.0 4102.1 2276.3 814.3 1817.4 126.3 946.3 21.6 2430.3 58.9 7.1 6823.9 5706.7 2853.5 7378.0 115.0 3013.4 3110.9 3070.0 30.0 6073.8 168.0 926.9 7.5 23.0 37545.1 9094.3 1143.8 346.6 9900.7 8570.5 224.3 4962.3 8.7 131.5 3234.0 2978.8 28.7 13.2 1718.7 997.6 1573.4 1283.0 5881.5 3218.9 17431.0 S100A7 "PSOR1, S100A7c" ENSG00000143556 "S100 calcium binding protein A7" P31151 1 153457744-153460651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 1065.7;lymphoid tissue: 1239.6;skin 1: 346.5;vagina: 1020.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 59.3;Club cells: 70.4;Ionocytes: 18.3;Suprabasal keratinocytes: 89.6;Syncytiotrophoblasts: 26.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 1201.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 7.2;SK-BR-3: 16.9" "CAB001453, HPA006997, CAB033766" Enhanced Uncertain Cytosol "Secreted in other tissues" NA NA 14000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB001453: AB_564004, CAB033766: AB_2269963, HPA006997: AB_1079860" "unprognostic (3.28e-1)" "unprognostic (9.85e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-2)" "unprognostic (3.17e-1)" "unprognostic (2.94e-2)" "unprognostic (1.03e-2)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (2.99e-1)" "unprognostic (5.41e-2)" "unprognostic (1.21e-2)" 1.0 0.2 0.9 0.0 0.8 0.8 15.6 1.4 2.1 174.8 0.7 0.3 0.0 1.2 27.6 1065.7 0.3 0.2 0.5 0.8 0.8 0.1 0.5 0.4 0.2 0.9 0.8 0.5 0.4 0.0 0.2 0.2 0.8 0.5 0.0 0.0 55.5 0.2 0.4 346.5 0.2 1.4 0.8 0.3 0.4 0.3 0.7 12.4 0.2 0.0 1239.6 1.2 1020.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 7.2 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.7 16.9 0.0 0.9 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 1.4 2.1 0.8 0.8 0.9 0.8 0.8 0.8 0.7 1.1 0.0 0.0 0.0 0.0 0.0 11.7 0.2 59.3 0.0 0.0 1.1 0.0 0.0 0.0 70.4 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 1.9 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 6.3 0.0 0.0 0.0 4.7 0.2 0.2 3.8 89.6 26.4 0.1 8.4 0.6 0.4 S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 4126.5;Kupffer cells: 6348.0;Macrophages: 3758.3;monocytes: 6932.6;Squamous epithelial cells: 8480.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in some" 24 "hTCEpi: 241.8;SK-BR-3: 719.0;THP-1: 400.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" 582.3 54.3 41.7 1245.8 45.6 35382.0 70.0 43.4 88.0 5650.6 45.5 55.2 15.4 23.1 5.5 24565.6 236.1 99.0 121.1 40.9 42.7 103.0 176.7 1061.7 29.5 47.7 44.8 25.8 52.0 9.6 41.7 205.8 50.7 43.1 14.7 5.6 3988.2 5.0 48.5 267.3 47.7 430.2 44.2 3239.5 93.8 16.2 45.5 281.3 48.8 174.8 8952.6 561.9 11166.4 46.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.0 1.3 0.0 0.3 12.4 0.0 18.7 0.0 0.1 0.0 3.5 0.0 0.0 0.0 5.6 0.1 0.0 241.8 0.0 7.5 0.0 0.0 0.0 9.6 1.2 0.0 0.9 0.4 1.5 0.3 0.0 0.0 0.4 5.8 1.0 0.0 0.0 0.4 0.5 3.6 719.0 0.0 0.0 4.7 400.6 10.6 0.0 0.2 0.9 0.1 0.2 1.3 2.7 0.3 13.9 0.0 848.0 26833.7 3023.7 33.4 1999.2 49.2 57.2 21.8 18.2 4686.1 23.5 21.6 23.3 52973.6 27.1 493.1 188.1 37.1 24979.9 41.7 45.6 43.4 88.0 40.9 42.7 47.7 44.8 50.7 44.2 45.5 46.2 1.1 224.4 489.8 0.0 77.2 19.6 3.5 4126.5 50.7 0.0 13.2 3.9 10.0 70.1 817.0 14.7 0.0 5.8 67.1 0.3 0.0 1.0 210.7 0.5 0.6 33.1 0.0 143.5 0.0 0.9 8.5 61.3 1.1 0.5 227.1 0.1 76.1 54.6 417.5 0.0 0.0 0.2 207.5 6348.0 5.1 172.4 4.1 3758.3 0.0 0.0 6932.6 0.0 289.4 0.0 0.0 1.4 0.0 1.5 26.1 0.9 0.0 25.0 162.8 0.0 0.0 7.7 32.3 2.1 1.0 8480.1 113.2 6.7 91.4 0.0 0.0 31.3 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 S100B S100beta ENSG00000160307 "S100 calcium binding protein B" P04271 21 46598604-46605208 "Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 1499.3;choroid plexus: 781.0" "Cell type enhanced" "Detected in many" "Astrocytes: 126.3;Breast myoepithelial cells: 124.8;Granulosa cells: 261.7;Langerhans cells: 206.8;Melanocytes: 99.6;Oligodendrocytes: 332.1" "Group enriched" "Detected in all" 58 "glioma: 463.5;melanoma: 495.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 360.9" "Lineage enriched" "Detected in all" 6 "T-cells: 360.9" "Group enriched" "Detected in some" 7 "SK-MEL-30: 547.1;WM-115: 992.8" "CAB000073, HPA015768, CAB078196" Enhanced Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 300000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "CAB000073: AB_10013383, CAB078196: AB_2665776, HPA015768: AB_1856538" "unprognostic (5.67e-3)" "unprognostic (6.39e-3)" "unprognostic (2.08e-3)" "unprognostic (2.08e-2)" "unprognostic (4.54e-3)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.68e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.57e-3)" "unprognostic (6.70e-2)" "unprognostic (4.41e-7)" "unprognostic (3.55e-2)" "unprognostic (7.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" 151.1 25.7 877.1 10.5 1072.5 2.3 87.0 1254.5 1191.2 28.6 781.0 121.0 7.4 2.4 12.1 14.6 6.9 14.3 28.1 858.4 989.0 3.6 3.2 6.4 21.4 1491.0 1054.2 5.6 5.0 0.3 44.7 0.8 1359.0 29.3 14.2 14.1 19.3 26.2 3.6 15.8 36.3 6.8 1162.2 26.2 23.6 2.4 998.8 18.4 5.2 6.4 20.3 15.9 26.9 1499.3 0.5 0.0 110.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.9 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 15.9 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 2.5 0.0 0.0 547.1 0.0 0.1 0.5 0.0 0.3 0.3 0.0 3.2 0.0 0.3 0.0 1.4 6.7 992.8 0.1 0.5 0.2 360.9 9.5 103.3 0.2 1.0 67.6 16.3 1.4 3.2 153.1 3.2 58.7 10.1 3.9 0.0 63.6 877.1 1072.5 1254.5 1191.2 858.4 989.0 1491.0 1054.2 1359.0 1162.2 998.8 1499.3 4.5 3.2 4.8 126.3 4.6 16.8 0.7 0.0 17.6 1.3 41.2 124.8 6.0 0.0 0.0 0.0 0.0 0.0 14.7 0.1 0.0 0.1 0.4 0.1 0.1 2.7 0.0 2.7 0.9 0.0 0.1 4.4 0.5 0.2 0.0 261.7 4.6 0.4 9.3 0.0 1.4 0.0 0.0 38.6 206.8 1.7 5.6 37.0 99.6 9.4 33.3 25.7 63.8 83.4 332.1 0.1 0.0 0.0 2.2 0.1 0.0 0.1 0.0 4.7 0.0 5.6 7.8 0.1 0.1 0.7 12.6 0.1 37.9 0.0 0.2 0.4 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 SACS "ARSACS, DKFZp686B15167, DNAJC29, KIAA0730, PPP1R138, SPAX6" ENSG00000151835 "Sacsin molecular chaperone" Q9NZJ4 13 23328826-23433740 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5;Excitatory neurons: 86.3;Inhibitory neurons: 108.2;Oligodendrocyte precursor cells: 76.4;Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017714 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB017714: " "unprognostic (1.22e-1)" "unprognostic (2.18e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.26e-2)" "unprognostic (1.66e-1)" "unprognostic (2.05e-3)" "unprognostic (2.59e-2)" "unprognostic (2.49e-1)" "unprognostic (4.14e-2)" "unprognostic (5.05e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.21e-6)" "unprognostic (2.84e-1)" "unprognostic (4.06e-2)" "unprognostic (3.67e-2)" "unprognostic (7.65e-4)" 4.8 4.4 4.7 4.0 10.0 5.6 4.3 7.2 16.1 4.8 0.0 8.0 0.9 6.2 2.7 3.7 5.8 2.2 8.7 7.6 3.0 3.2 2.2 4.8 4.3 8.4 5.2 4.7 4.8 15.2 6.8 1.3 9.4 7.6 1.5 4.6 6.6 2.3 14.0 2.4 5.0 4.9 2.0 8.5 5.1 6.8 10.3 4.2 2.6 13.1 3.6 9.9 4.4 11.4 8.1 10.5 21.3 6.5 6.5 24.3 3.1 18.1 23.2 6.9 5.7 5.0 4.2 5.5 7.4 38.8 9.0 1.6 30.7 10.8 22.5 12.9 12.6 20.7 8.1 7.4 4.8 38.1 7.9 7.8 2.5 44.3 21.2 9.7 23.1 17.0 12.1 2.6 31.6 3.8 13.6 14.6 17.5 2.8 8.2 16.0 38.7 16.7 12.0 0.9 15.4 14.8 10.0 3.6 7.8 9.7 1.9 10.0 49.8 21.1 17.4 11.5 34.6 5.0 5.7 13.3 10.1 13.2 18.7 0.0 0.1 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.4 0.7 0.2 0.3 0.0 0.3 0.0 0.3 0.7 0.1 4.7 10.0 7.2 16.1 7.6 3.0 8.4 5.2 9.4 2.0 10.3 11.4 10.3 0.0 1.3 70.5 14.5 6.1 5.4 2.0 6.8 16.5 8.2 8.0 21.3 1.5 1.4 1.8 0.0 0.4 15.3 0.2 0.0 9.0 13.1 5.6 28.1 11.6 1.2 9.7 86.3 10.4 1.5 17.4 3.1 3.3 2.5 18.8 3.6 0.7 3.4 25.2 108.2 0.4 2.0 4.9 19.4 11.6 4.1 8.1 8.8 19.7 3.9 13.6 6.2 76.4 111.0 16.7 0.2 5.3 12.9 8.1 0.0 1.3 1.2 5.3 13.1 45.6 20.9 20.5 9.5 5.3 5.1 0.0 18.1 20.0 0.8 2.9 SALL4 "dJ1112F19.1, ZNF797" ENSG00000101115 "Spalt like transcription factor 4" Q9UJQ4 20 51782331-51802521 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.9;thyroid gland: 5.8" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 26.9" "Cancer enriched" "Detected in many" 11 "testis cancer: 22.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "NK-cell: 2.5" "Lineage enriched" "Detected in single" 9 "NK-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 25.0;AN3-CA: 17.5;BEWO: 33.2;NTERA-2: 60.2;SiHa: 15.6;SuSa: 39.7" "Not detected" "Not detected" "HPA015291, HPA015791" Enhanced Enhanced Nucleoplasm Yes No "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA015291: AB_1856548, HPA015791: AB_1856547" "unprognostic (1.30e-1)" "unprognostic (2.35e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-3)" "unprognostic (3.55e-2)" "unprognostic (7.43e-2)" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (9.23e-2)" "unprognostic (2.50e-2)" "unprognostic (2.39e-2)" "unprognostic (2.42e-8)" "unprognostic (5.90e-3)" "unprognostic (1.82e-1)" "unprognostic (5.00e-5)" "unprognostic (7.41e-2)" 0.2 0.3 0.2 0.2 0.2 0.8 0.2 0.4 0.2 0.2 0.3 0.2 0.1 0.2 0.4 0.2 0.2 0.0 0.1 0.2 0.4 0.8 1.6 0.2 0.1 0.2 0.3 0.1 2.1 2.0 0.5 0.2 0.2 2.4 0.2 0.5 0.9 0.2 0.1 0.2 0.4 0.1 0.2 0.5 0.2 3.9 0.3 0.0 5.8 0.0 0.1 0.4 0.1 0.4 0.0 1.7 25.0 17.5 0.0 0.1 33.2 0.0 0.2 0.1 0.3 9.0 0.2 0.0 0.3 0.3 0.3 4.3 0.2 0.1 0.3 0.4 0.0 0.0 7.0 0.4 0.1 0.0 1.9 0.7 0.5 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.0 1.8 0.0 0.1 60.2 0.2 0.4 2.3 0.0 0.0 0.0 0.5 5.7 3.1 15.6 0.1 1.5 39.7 0.1 1.0 0.0 0.9 3.3 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.2 0.2 0.4 0.2 0.3 0.2 0.2 0.3 0.4 0.1 0.0 2.0 1.6 0.0 0.0 1.1 0.1 0.0 0.4 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 3.6 0.0 0.2 0.1 0.2 1.2 0.0 4.1 0.2 0.0 0.4 0.0 0.4 0.0 0.2 0.0 0.6 0.2 26.9 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.2 1.0 2.0 2.0 0.2 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.4 0.0 0.2 0.2 0.7 5.5 0.0 0.0 0.0 0.0 0.1 0.0 1.2 SART1 "Ara1, HAF, SNRNP110, Snu66" ENSG00000175467 "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP" O43290 11 65961728-65980137 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Allergen, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031188, HPA031189, HPA031190" Supported Enhanced "Nuclear speckles,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Golgi apparatus" "HPA031188: AB_10600092, HPA031189: AB_10601854, HPA031190: AB_10602289" "unprognostic (2.93e-2)" "unprognostic (1.13e-2)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "unprognostic (6.99e-2)" "unprognostic (2.52e-3)" "unprognostic (8.15e-2)" "unprognostic (8.97e-2)" "unprognostic (2.10e-1)" "unprognostic (2.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" 24.6 18.3 15.5 18.3 16.8 41.6 23.1 15.4 17.4 29.2 14.7 26.0 15.6 29.1 8.0 22.7 25.6 8.6 23.2 14.9 16.1 20.4 21.8 22.9 20.3 16.6 16.2 29.2 25.8 11.7 21.4 14.0 15.9 21.7 7.7 8.0 22.2 14.4 38.1 32.0 24.3 10.9 14.6 32.7 24.8 23.5 15.7 20.9 23.5 13.0 13.3 26.2 24.6 17.9 50.4 60.8 27.2 36.8 26.1 20.7 40.8 37.5 27.2 43.8 28.6 44.2 34.3 56.9 42.4 33.8 52.9 48.7 34.6 35.6 22.0 45.8 33.5 65.6 43.6 41.4 39.0 57.4 52.7 26.2 26.4 40.8 36.3 17.4 27.6 42.3 42.2 39.8 25.6 92.6 74.0 83.5 45.7 27.3 55.9 80.8 39.0 60.7 18.4 33.7 30.5 43.0 35.6 37.2 45.5 12.6 41.7 47.0 40.6 54.5 53.0 53.9 54.1 59.6 49.4 48.3 45.0 28.8 47.0 1.4 2.8 8.1 4.3 3.5 3.6 3.9 4.8 4.4 3.6 3.5 3.5 3.9 4.1 2.8 2.0 3.2 5.4 1.8 15.5 16.8 15.4 17.4 14.9 16.1 16.6 16.2 15.9 14.6 15.7 17.9 17.5 6.4 9.1 7.8 27.8 22.7 24.0 12.2 17.6 19.2 12.2 9.1 9.4 21.5 11.3 16.5 10.4 34.1 27.2 30.5 5.9 23.7 9.0 14.2 16.3 19.8 12.5 32.8 5.1 29.3 31.9 17.6 21.9 16.8 32.4 21.8 21.0 15.6 29.4 16.8 4.8 26.5 16.2 22.5 23.6 8.7 37.0 22.9 17.8 6.5 35.7 23.8 34.0 7.1 7.8 26.3 20.1 33.1 31.2 20.5 28.3 18.5 17.5 26.0 32.9 27.6 34.9 26.7 29.7 18.3 21.7 45.3 28.4 15.5 27.5 18.2 SBDS "CGI-97, FLJ10917, SDS, SWDS" ENSG00000126524 "SBDS ribosome maturation factor" Q9Y3A5 7 66987680-66995587 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2042.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028891 Approved Supported Nucleoplasm,Cytosol NA NA 190000 "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA028891: AB_10601500" "prognostic unfavorable (1.49e-4)" "unprognostic (1.87e-2)" "unprognostic (5.73e-2)" "unprognostic (1.71e-3)" "unprognostic (8.06e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.07e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (6.99e-2)" "unprognostic (7.84e-3)" "unprognostic (4.59e-1)" "unprognostic (1.04e-2)" "unprognostic (9.38e-3)" "unprognostic (1.83e-1)" "unprognostic (2.30e-1)" "unprognostic (5.06e-3)" 139.1 107.5 136.1 57.9 152.1 157.2 113.7 151.2 168.3 97.3 115.8 143.6 127.8 117.2 83.3 128.6 99.2 84.9 238.0 133.1 148.4 117.8 126.8 113.8 43.8 156.2 142.3 90.1 89.3 145.0 87.4 106.2 155.0 107.9 111.6 90.3 80.7 122.6 374.0 92.0 114.2 128.2 152.6 57.3 104.6 60.9 143.4 38.8 107.0 263.3 52.5 113.9 90.7 169.7 168.3 68.9 59.9 54.6 212.7 157.9 67.0 281.4 225.4 206.1 157.1 143.1 83.0 62.2 209.7 253.5 136.3 80.1 101.7 164.3 219.4 59.8 136.4 31.1 125.9 86.6 188.9 78.1 40.8 144.0 215.1 157.0 269.8 105.9 129.2 39.7 227.2 65.0 324.2 100.0 41.8 112.4 67.2 227.3 165.9 31.3 132.6 129.3 218.1 73.6 91.7 63.7 142.3 235.5 194.3 131.0 176.2 64.8 176.4 276.5 96.7 142.5 205.4 40.6 51.4 141.0 95.7 125.5 157.4 75.5 33.2 61.4 64.7 37.7 81.7 62.8 82.7 75.2 33.4 59.9 104.4 85.7 13.0 51.8 35.1 45.4 80.2 62.2 136.1 152.1 151.2 168.3 133.1 148.4 156.2 142.3 155.0 152.6 143.4 169.7 169.9 304.5 128.0 10.7 101.6 464.2 466.2 213.2 145.7 73.7 118.5 154.0 286.6 108.7 160.3 92.0 12.5 130.5 98.0 270.9 262.2 177.4 583.0 93.0 131.2 153.2 101.9 51.3 12.5 165.7 232.1 197.7 96.8 128.2 150.0 29.7 138.5 102.1 107.0 58.9 15.3 221.9 142.4 47.2 238.1 2042.9 127.1 74.8 256.1 11.2 66.5 161.9 30.9 7.5 36.0 300.0 242.2 168.5 117.5 267.2 359.3 264.6 75.6 56.8 164.3 512.9 266.2 86.3 47.9 129.9 430.0 398.5 144.5 132.2 165.4 318.5 SCGB1A1 "CC10, CC16, CCSP, UGB" ENSG00000149021 "Secretoglobin family 1A member 1" P11684 11 62405103-62423195 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Phospholipase A2 inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lung: 3079.0" "Cell type enriched" "Detected in some" 4 "Club cells: 43564.7" "Cancer enriched" "Detected in many" 8 "lung cancer: 215.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 71 "HaCaT: 1977.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025686, HPA031828" Enhanced "Secreted in other tissues" NA NA 13000000 "Cluster 19: Lung - Lung function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025686: , HPA031828: AB_2674061" "unprognostic (2.40e-3)" "unprognostic (1.55e-2)" "unprognostic (5.46e-2)" "unprognostic (2.70e-2)" "unprognostic (4.69e-3)" "unprognostic (2.12e-2)" "unprognostic (1.23e-2)" "unprognostic (2.31e-2)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" 1.1 2.0 0.6 0.9 0.7 0.1 0.3 1.3 1.1 0.6 0.3 0.2 0.4 0.2 0.7 11.0 334.2 0.2 0.6 0.5 0.6 0.2 0.4 3079.0 0.2 0.6 0.9 2.0 1.9 0.0 2.4 1.7 0.5 85.1 0.0 0.2 0.5 0.9 0.3 0.3 1.6 0.0 0.5 7.2 4.3 0.2 1.0 2.8 0.4 0.0 5.9 0.2 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 1977.1 0.0 0.3 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.3 27.9 0.0 0.0 0.0 0.0 0.1 0.2 0.8 0.0 1.1 0.0 0.0 0.6 1.4 0.4 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.1 0.4 0.0 0.0 1.0 2.0 0.0 1.0 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.3 1.1 0.5 0.6 0.6 0.9 0.5 0.5 1.0 0.5 0.0 1125.0 2573.3 0.0 0.0 0.0 71.4 3938.5 0.0 0.0 0.0 0.0 0.0 0.0 43564.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 113.5 0.0 0.0 0.1 0.0 0.0 304.5 0.0 0.5 691.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4534.8 0.0 0.0 0.7 0.0 128.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.8 0.0 0.0 0.0 134.7 0.0 0.0 9997.0 0.0 0.0 0.0 850.3 0.0 0.0 3.9 0.0 0.0 83.7 0.0 0.0 800.2 SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1227.2;cervix: 4002.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3242.1;Glandular and luminal cells: 3417.9" "Group enriched" "Detected in many" 6 "breast cancer: 625.1;endometrial cancer: 226.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 10.4" HPA035318 Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "HPA035318: AB_10610421" "unprognostic (8.76e-2)" "unprognostic (2.14e-1)" "prognostic favorable (3.46e-6)" "unprognostic (2.39e-2)" "unprognostic (5.89e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "prognostic favorable (8.03e-6)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" 12.9 4.9 4.1 0.0 4.0 0.0 1227.2 3.2 5.4 4002.8 13.8 0.3 0.1 89.0 355.8 10.1 110.3 0.1 3.1 3.5 4.4 10.1 0.2 0.1 0.1 4.7 5.7 1.1 4.5 0.5 5.2 0.2 4.2 8.6 0.2 1.8 69.2 2.9 7.2 342.4 0.4 0.0 3.5 0.0 0.3 0.2 4.3 0.4 0.6 6.0 0.0 0.2 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.1 0.0 1.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.0 3.2 5.4 3.5 4.4 4.7 5.7 4.2 3.5 4.3 4.6 2.1 0.0 0.0 0.0 1.6 27.4 4.8 0.0 0.0 0.5 647.8 251.6 10.9 0.0 0.0 7.3 0.0 0.0 5.3 0.0 23.5 0.3 0.0 3242.1 409.9 12.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 3417.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 15.0 823.6 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 46.1 0.0 0.9 0.0 0.2 8.6 0.0 0.0 0.0 7.0 0.1 20.0 0.0 0.0 1.1 SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 2021.0;epididymis: 1372.0" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2506.4;Glandular and luminal cells: 2597.0" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 8.6" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" 0.2 0.0 0.0 0.2 0.0 0.0 57.8 0.0 0.0 2021.0 0.1 12.7 1.3 118.8 1372.0 4.2 238.4 13.4 0.2 0.1 0.4 1.9 0.1 2.4 0.0 3.5 1.4 0.7 17.2 1.1 5.1 0.1 0.8 6.8 16.3 0.0 29.6 15.6 0.0 8.6 1.0 2.2 0.5 0.0 45.9 0.0 1.1 2.7 5.8 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 1.6 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.5 1.4 0.8 0.5 1.1 0.2 0.6 0.0 4.8 0.0 0.4 0.1 3.8 4.8 0.0 0.0 123.6 71.0 0.0 48.6 10.1 16.5 0.0 0.2 1.6 9.7 3.9 6.6 0.0 2506.4 397.7 7.6 37.1 0.0 0.0 5.3 0.0 3.8 26.5 2597.0 0.0 0.3 0.0 0.1 4.9 0.0 0.0 59.9 10.2 0.3 0.0 0.0 0.0 14.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 15.3 10.8 0.0 0.0 27.0 0.7 0.1 109.3 0.0 0.0 0.0 8.5 0.0 0.0 1.7 0.4 0.0 13.7 0.1 7.0 16.6 SCGB2A2 "MGB1, MGC71974, PSBP1, UGB2" ENSG00000110484 "Secretoglobin family 2A member 2" Q13296 11 62270158-62273160 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "breast: 2805.9;skin 1: 708.1" "Group enriched" "Detected in some" 11 "Breast glandular cells: 2119.6;Breast myoepithelial cells: 1028.8;Melanocytes: 1762.7" "Cancer enriched" "Detected in many" 23 "breast cancer: 823.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 124 "SK-BR-3: 18.0" CAB026270 Enhanced "Secreted in female reproductive system" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "CAB026270: AB_912980" "unprognostic (2.38e-1)" "unprognostic (7.28e-2)" "prognostic favorable (9.57e-8)" "unprognostic (4.17e-1)" "unprognostic (3.75e-1)" 34.4 0.2 0.0 0.0 0.0 0.0 2805.9 0.0 0.0 309.2 0.0 0.4 0.0 4.1 0.0 76.6 0.1 0.0 4.0 0.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 1.6 1.3 0.0 0.2 0.0 0.0 159.3 0.1 1.8 708.1 0.2 0.0 0.0 0.2 0.3 1.1 0.0 2.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.6 49.6 0.3 0.0 0.0 0.0 2119.6 1028.8 0.1 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 1.4 41.9 21.6 11.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 141.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 3.2 1762.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 10.9 0.0 9.2 0.0 0.0 0.0 SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 491.6;liver: 484.7;skin 1: 447.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 267.4;Hepatocytes: 603.1;Squamous epithelial cells: 246.6;Syncytiotrophoblasts: 250.8;Urothelial cells: 492.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 7 "midbrain: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 482.2;hTCEpi: 436.6;U-251 MG: 470.0;U-266/70: 467.4;U-266/84: 1069.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" NA NA 63100000 3100000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 22: Epithelial cell types - Mixed function" "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" 2.4 17.4 0.7 17.2 0.2 1.2 23.8 2.3 0.8 127.2 0.7 61.8 75.8 2.2 19.9 491.6 10.5 77.1 0.6 0.3 2.0 99.5 484.7 59.6 7.3 0.6 17.3 1.6 16.6 5.4 2.0 32.6 0.8 56.3 33.3 0.7 85.8 25.9 1.6 447.4 53.6 2.2 0.2 20.1 87.3 3.3 2.5 5.1 18.3 0.0 43.2 104.8 242.1 0.1 252.6 137.6 42.7 108.1 11.6 1.6 134.9 68.7 65.4 62.7 52.8 29.5 148.9 0.3 24.8 48.8 34.8 241.4 19.0 482.2 41.8 1.3 12.5 0.0 12.2 150.2 10.3 11.0 1.0 6.4 436.6 56.5 132.9 87.2 6.9 0.0 6.4 94.7 34.0 149.6 0.6 2.6 38.7 189.6 263.1 5.3 15.7 189.9 80.5 370.0 12.4 99.7 51.9 342.4 15.2 17.1 34.5 2.8 10.7 246.9 78.6 9.2 470.0 467.4 1069.8 1.0 74.5 0.6 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 2.3 0.8 0.3 2.0 0.6 17.3 0.8 0.2 2.5 0.1 0.4 93.0 99.0 0.0 33.0 113.9 189.1 162.8 81.4 0.6 29.9 26.7 0.9 267.4 161.8 42.3 0.0 3.8 0.7 147.2 31.3 61.3 0.1 16.6 5.0 3.5 10.8 13.5 0.3 21.8 46.3 5.0 55.0 22.9 6.3 7.5 7.5 603.1 2.3 21.9 0.2 73.1 50.8 10.6 11.9 0.3 0.6 2.5 21.4 0.0 0.6 0.3 0.0 1.0 0.0 111.4 78.0 1.2 165.1 78.0 106.5 88.5 43.4 0.4 0.0 0.1 15.0 1.0 14.0 246.6 229.0 250.8 4.0 0.1 85.1 492.8 SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 515.9;Pancreatic endocrine cells: 476.4;Suprabasal keratinocytes: 472.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 512.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 320000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" 68.0 73.1 90.3 26.3 116.8 10.1 113.1 90.2 120.7 53.0 68.5 102.6 37.8 53.0 11.8 124.3 76.6 72.2 65.9 66.4 90.2 166.9 410.9 168.3 9.8 120.5 127.8 26.3 90.3 34.7 43.2 27.3 95.4 53.0 62.6 35.1 103.7 45.9 101.5 190.4 42.4 53.8 89.9 32.3 140.1 47.1 151.9 8.2 51.1 35.4 35.2 124.7 68.7 71.4 162.1 20.7 11.1 0.8 269.2 164.3 474.4 201.5 273.0 222.9 158.6 242.7 400.0 0.2 88.1 255.4 224.5 203.1 8.2 512.2 269.0 46.7 7.4 4.9 15.8 95.8 292.4 1.0 8.2 223.1 336.5 92.4 223.2 123.3 29.9 3.7 8.2 0.5 130.5 159.9 0.2 14.2 20.4 139.9 63.1 0.3 99.7 0.6 367.7 211.7 4.3 15.6 277.2 169.4 51.4 125.2 123.1 9.7 56.4 169.4 141.4 17.3 131.8 8.5 6.7 0.7 266.2 16.4 103.2 1.5 1.6 0.4 0.7 0.6 2.1 0.3 2.0 0.8 1.5 0.3 0.4 0.5 0.8 0.7 0.6 1.4 4.4 0.7 90.3 116.8 90.2 120.7 66.4 90.2 120.5 127.8 95.4 89.9 151.9 71.4 21.9 291.7 391.2 106.7 3.8 373.7 322.2 352.8 75.1 14.5 208.8 90.6 59.3 245.9 218.4 189.4 12.5 38.9 7.8 174.3 64.6 296.0 1.2 116.6 20.8 16.0 55.1 7.4 0.2 515.9 230.0 43.0 170.7 179.0 13.9 10.8 11.4 260.6 18.8 0.0 0.3 131.9 160.7 19.3 106.0 3.8 4.1 39.5 76.5 5.6 33.0 10.0 0.0 3.5 1.8 476.4 121.7 5.3 2.1 284.2 59.0 153.8 178.6 23.6 0.0 34.9 33.5 1.8 2.5 170.9 472.8 67.5 16.8 3.2 90.7 423.9 SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218241-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 601.0;skeletal muscle: 479.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria No No 360000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavorable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favorable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" 70.6 148.0 60.5 29.6 62.7 38.4 65.8 78.7 71.3 50.2 63.2 131.9 148.9 53.2 27.3 67.1 50.3 33.9 601.0 60.8 73.4 139.1 276.8 54.3 43.1 74.1 62.7 65.8 71.5 122.9 44.8 28.8 75.7 46.3 82.1 42.7 66.8 35.6 479.0 58.9 116.8 36.1 61.7 66.4 115.6 56.4 71.7 41.8 49.6 224.8 36.5 63.2 56.3 63.7 88.4 154.2 54.8 95.0 96.9 68.5 154.1 63.3 81.8 107.2 108.4 163.9 115.9 108.3 218.6 70.2 92.1 111.8 102.4 129.7 66.3 241.9 98.9 50.1 390.8 224.1 60.0 69.5 70.7 70.6 84.3 83.6 33.7 93.6 123.9 83.5 84.6 83.1 48.7 155.8 93.9 206.9 19.3 101.4 193.5 119.0 84.6 223.2 245.4 122.7 62.3 35.4 332.5 205.5 90.7 36.1 115.0 93.2 91.1 80.3 82.1 48.2 52.5 93.0 40.9 79.8 81.6 99.9 52.5 66.6 70.8 88.1 95.2 85.7 86.8 79.5 92.5 94.5 93.3 73.3 89.2 85.0 14.1 85.5 74.7 59.5 149.3 111.3 60.5 62.7 78.7 71.3 60.8 73.4 74.1 62.7 75.7 61.7 71.7 63.7 29.4 35.3 71.1 20.2 50.9 61.2 81.4 105.8 31.3 51.0 24.6 17.0 272.6 64.3 78.5 75.4 102.2 109.6 39.3 169.7 142.8 94.7 58.7 39.1 30.1 39.1 47.5 56.8 34.4 44.9 102.8 49.4 47.9 48.5 43.7 64.8 47.5 167.0 67.5 101.0 39.9 96.3 105.8 41.0 55.0 28.8 68.3 38.8 90.7 12.2 60.2 50.7 52.5 19.1 37.9 54.2 100.1 55.7 67.5 37.0 274.4 190.7 75.2 87.2 78.9 33.2 51.7 96.9 54.3 40.9 35.9 154.7 56.7 85.0 160.1 88.2 SDHAF2 "C11orf79, FLJ20487, PGL2, SDH5" ENSG00000167985 "Succinate dehydrogenase complex assembly factor 2" Q9NX18 11 61430042-61446733 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039464, HPA039732" Supported Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Mitochondria, Cytosol" Nucleoli "HPA039464: AB_10962146, HPA039732: AB_10962868" "unprognostic (5.31e-2)" "unprognostic (1.12e-2)" "unprognostic (3.13e-1)" "unprognostic (1.30e-2)" "unprognostic (1.40e-1)" "unprognostic (6.71e-2)" "unprognostic (1.98e-3)" "unprognostic (9.06e-2)" "unprognostic (2.17e-1)" "unprognostic (2.09e-3)" "unprognostic (4.21e-3)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (1.45e-1)" "unprognostic (4.48e-2)" 27.5 37.1 36.2 26.4 37.4 45.6 28.9 37.9 38.2 23.8 37.4 27.2 24.7 23.8 34.8 28.8 28.7 25.5 40.4 35.9 40.2 36.5 46.4 23.8 39.9 37.9 37.6 26.9 24.0 32.9 41.0 24.9 37.9 29.0 29.1 23.4 26.3 20.9 38.9 26.3 27.0 26.9 37.7 34.7 27.6 22.1 38.0 38.0 28.6 44.7 41.6 32.8 21.7 39.2 45.0 58.4 36.5 25.1 57.2 52.2 27.0 33.3 58.0 48.9 41.8 52.8 46.8 42.3 58.4 55.6 62.8 45.4 45.4 51.4 56.6 60.4 39.7 33.2 35.5 71.9 52.8 41.4 48.1 55.6 58.7 50.2 45.8 35.3 80.8 43.5 42.2 50.9 63.5 86.0 49.2 89.3 56.1 47.0 78.6 45.9 45.9 76.6 63.7 57.9 36.9 40.6 46.9 53.5 99.0 38.5 83.0 40.2 53.3 45.0 32.7 54.3 37.5 31.2 51.2 54.7 43.4 37.3 46.0 125.3 68.8 126.6 82.5 64.5 103.1 89.7 93.0 91.7 55.9 84.8 101.5 97.5 97.9 97.9 53.3 63.3 126.7 78.6 36.2 37.4 37.9 38.2 35.9 40.2 37.9 37.6 37.9 37.7 38.0 39.2 32.8 35.3 33.2 11.1 28.9 20.6 34.6 53.7 10.2 14.0 27.9 35.1 22.3 14.3 33.5 29.5 6.2 77.0 41.9 29.5 54.8 55.3 15.8 19.3 21.7 36.5 34.2 30.3 13.2 60.3 51.4 28.4 16.8 19.0 32.3 22.2 42.5 42.3 52.7 15.2 13.3 31.4 59.0 36.5 22.8 17.8 31.4 29.7 44.4 8.4 66.4 49.4 69.0 16.6 18.1 62.9 34.9 30.9 16.3 30.8 34.0 51.9 31.5 19.7 32.9 17.3 27.2 23.1 25.8 10.9 22.4 99.6 41.5 45.1 27.6 38.8 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SDHC "CYB560, cybL, PGL3" ENSG00000143252 "Succinate dehydrogenase complex subunit C" Q99643 1 161314381-161363206 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 776.7;Proximal tubular cells: 916.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.48e-2)" "unprognostic (6.88e-2)" "unprognostic (6.38e-3)" "unprognostic (1.86e-2)" "unprognostic (1.90e-2)" "unprognostic (5.02e-2)" "unprognostic (7.08e-2)" "unprognostic (2.33e-1)" "unprognostic (7.38e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.20e-4)" "unprognostic (9.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.19e-3)" "unprognostic (3.77e-1)" 128.9 143.7 73.7 64.1 79.7 60.5 100.3 84.5 85.1 78.7 92.9 118.9 127.8 70.9 76.0 109.7 98.6 63.3 154.1 68.4 83.4 285.7 319.4 65.5 74.7 78.8 79.1 69.2 62.5 173.6 52.4 73.1 76.7 77.3 132.2 84.3 74.8 84.7 277.4 69.8 101.4 101.4 85.1 62.8 89.9 52.7 84.8 93.1 89.5 288.4 105.1 88.4 61.3 85.6 161.1 129.7 157.5 147.7 248.3 213.3 196.3 150.9 190.3 180.3 137.3 185.4 208.7 53.7 190.6 214.8 121.6 178.5 244.3 214.2 193.2 185.6 205.6 110.2 106.6 196.7 126.9 193.8 109.1 211.5 181.7 174.3 119.4 167.9 177.5 164.0 178.9 43.8 266.3 167.0 152.4 112.5 145.4 376.3 123.7 131.6 151.0 217.1 330.3 167.8 118.3 180.7 211.0 385.1 225.4 207.9 342.1 259.3 133.5 103.7 125.1 127.9 147.3 173.3 287.8 269.4 140.3 139.2 193.6 88.6 111.0 65.7 76.6 99.6 79.6 68.6 66.2 75.4 136.1 65.7 71.2 71.0 52.0 66.9 87.5 100.6 78.3 130.0 73.7 79.7 84.5 85.1 68.4 83.4 78.8 79.1 76.7 85.1 84.8 85.6 50.9 44.8 59.4 14.7 70.1 61.8 151.2 342.6 59.7 74.9 81.4 58.3 94.0 131.5 163.5 150.8 64.6 248.0 65.5 95.9 776.7 218.4 18.6 87.1 63.8 80.7 66.8 81.4 19.3 145.2 248.5 79.8 79.5 62.6 58.3 66.6 83.2 249.1 237.3 72.3 27.4 103.4 215.7 100.6 74.4 34.7 102.9 94.6 129.9 9.4 176.1 107.8 107.1 17.6 24.5 142.7 89.5 109.1 71.9 100.2 139.1 916.5 177.9 69.3 52.6 74.5 94.4 115.3 114.4 111.2 76.4 307.6 72.0 215.7 154.2 155.0 SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 530.2;Proximal tubular cells: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" 117.5 95.7 60.0 84.5 63.1 72.9 102.6 68.6 76.3 92.5 65.1 185.2 208.1 88.2 96.7 126.7 92.6 85.6 254.7 60.1 65.4 319.9 391.8 79.3 131.7 63.4 62.5 91.6 77.8 152.4 37.0 95.0 63.2 87.9 190.8 37.4 112.6 100.9 354.7 64.3 175.6 98.1 64.7 85.1 101.1 34.1 63.7 102.5 136.8 449.6 124.8 117.9 76.4 68.2 84.0 67.3 58.1 89.4 212.0 170.7 97.3 97.5 147.6 106.8 132.2 244.8 222.1 155.5 288.4 131.0 156.1 203.5 175.4 139.8 129.8 129.9 92.4 142.8 51.9 140.1 165.6 222.4 107.5 189.6 160.2 110.5 189.1 124.6 153.0 109.6 156.0 208.7 135.0 95.2 143.9 215.0 77.4 333.8 211.6 126.2 145.8 294.4 221.6 175.2 83.5 55.8 135.3 194.8 107.0 81.8 198.9 164.2 108.0 103.8 132.3 114.7 95.0 59.1 73.2 270.7 58.8 297.0 100.5 233.7 293.3 208.8 158.4 390.1 173.1 235.2 170.8 168.8 308.7 198.1 204.3 191.8 257.5 207.9 322.9 151.7 189.9 348.9 60.0 63.1 68.6 76.3 60.1 65.4 63.4 62.5 63.2 64.7 63.7 68.2 104.3 80.1 51.1 12.4 78.0 81.6 102.2 262.2 83.6 12.2 61.0 78.4 216.5 120.1 108.1 90.1 8.4 154.3 55.2 203.8 530.2 82.9 9.9 41.6 67.6 76.4 50.4 70.2 9.6 58.9 124.1 104.6 75.4 41.2 65.9 32.3 76.8 169.7 162.9 11.8 11.2 129.1 154.6 97.1 74.4 37.0 104.1 94.2 76.5 9.4 118.6 52.9 75.2 8.0 9.7 54.1 134.2 99.6 80.9 61.6 253.1 449.9 60.5 18.9 92.1 78.3 110.7 70.4 55.8 127.1 74.4 179.0 71.4 86.2 176.0 98.6 SELE "CD62E, ELAM, ELAM1, ESEL" ENSG00000007908 "Selectin E" P16581 1 169722640-169764705 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 56.1" "Cell type enriched" "Detected in some" 4 "Endothelial cells: 379.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HUVEC TERT2: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" CAB002143 Enhanced NA NA 8140000 180000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002143: AB_563608" "unprognostic (2.39e-1)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.09e-2)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (1.59e-1)" "unprognostic (2.94e-1)" "unprognostic (3.63e-1)" "unprognostic (3.88e-1)" "unprognostic (9.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.56e-2)" "unprognostic (8.13e-3)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.55e-1)" 29.6 5.5 1.2 12.6 0.8 0.5 12.0 0.5 1.7 4.1 4.1 4.2 0.7 5.3 0.5 4.0 23.8 10.7 8.0 0.8 1.6 7.6 6.9 10.3 3.0 1.8 1.2 3.3 1.2 12.5 4.0 1.4 1.7 27.7 2.6 0.3 3.1 3.8 0.8 5.5 2.3 18.7 1.3 0.0 5.2 2.4 2.9 8.4 13.8 1.0 3.6 56.1 5.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.5 1.7 0.8 1.6 1.8 1.2 1.7 1.3 2.9 1.1 34.6 0.0 3.8 0.0 0.0 46.1 1.1 0.0 1.2 0.0 0.5 0.3 4.0 1.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.3 379.5 0.0 0.0 0.1 0.0 0.0 12.7 0.0 0.2 1.3 0.0 3.9 8.5 0.0 0.0 0.0 0.0 0.0 0.0 81.9 3.0 0.0 0.9 46.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.3 4.1 0.2 0.0 1.2 47.7 0.0 3.4 0.1 0.1 2.5 SELL "CD62L, hLHRc, LAM-1, LAM1, Leu-8, LNHR, LSEL, Lyam-1, LYAM1, PLNHR" ENSG00000188404 "Selectin L" P14151 1 169690665-169711702 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 150.4;lymphoid tissue: 231.4" "Group enriched" "Detected in many" 5 "B-cells: 221.4;dendritic cells: 206.0;Kupffer cells: 68.9;Macrophages: 86.3;monocytes: 208.7;NK-cells: 110.2;T-cells: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 11.2;JURKAT: 29.4;MOLT-4: 21.2;U-266/70: 38.8;U-698: 19.4;U-937: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002144, HPA051972" Enhanced Uncertain Cytosol NA NA 4700000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002144: AB_563862, HPA051972: AB_2797242" "prognostic favorable (3.76e-4)" "prognostic favorable (2.25e-4)" "unprognostic (1.52e-2)" "unprognostic (2.89e-2)" "unprognostic (7.87e-3)" "prognostic favorable (6.43e-4)" "unprognostic (1.39e-3)" "unprognostic (3.43e-1)" "unprognostic (2.70e-3)" "prognostic favorable (3.14e-4)" "unprognostic (1.42e-1)" "unprognostic (4.21e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (4.76e-2)" "unprognostic (8.71e-3)" "unprognostic (9.57e-2)" "unprognostic (1.01e-1)" 29.3 2.3 2.8 118.8 4.5 150.4 2.6 8.4 6.2 3.7 2.7 6.8 3.2 2.6 1.7 5.5 4.7 24.1 3.1 3.2 4.0 3.0 12.1 19.4 231.4 7.4 4.5 1.0 3.7 28.0 13.9 11.2 6.1 3.7 7.1 1.0 3.8 1.9 3.4 0.6 17.0 14.5 6.4 166.8 5.6 1.1 3.9 132.2 2.8 13.6 202.0 37.9 1.4 8.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.2 0.2 0.7 0.0 0.3 11.2 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 7.7 1.3 0.5 0.0 0.0 0.0 0.0 1.8 29.4 0.1 1.4 0.0 1.8 21.2 0.3 0.1 0.4 0.3 7.8 0.2 0.7 6.1 0.3 0.0 0.0 0.0 1.4 0.0 0.8 0.0 0.0 0.0 0.6 0.2 0.0 0.0 38.8 0.0 19.4 2.0 11.1 0.3 3688.4 992.6 1696.7 284.3 211.6 78.1 613.0 528.9 294.2 756.3 734.4 1169.2 683.6 4201.4 2551.1 93.1 622.9 1011.2 2052.5 2.8 4.5 8.4 6.2 3.2 4.0 7.4 4.5 6.1 6.4 3.9 8.0 1.8 9.6 13.7 0.7 221.4 0.4 0.3 0.0 0.6 0.1 0.5 0.3 0.6 2.8 1.8 11.0 0.0 13.9 206.0 0.1 0.0 0.2 0.0 0.1 0.0 3.4 0.0 25.2 0.2 0.0 0.6 3.3 2.6 0.1 10.1 0.5 3.9 1.1 5.6 0.0 0.1 0.1 0.0 68.9 2.7 0.2 0.6 86.3 1.8 1.0 208.7 2.5 110.2 0.0 0.8 0.1 0.0 0.0 25.8 0.0 0.0 0.9 1.5 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.1 28.5 104.9 0.5 0.0 0.6 SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 14.7;Endothelial cells: 51.8;Hepatic stellate cells: 33.9;Macrophages: 10.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 8.3;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.3;T-cells: 8.8" "Group enriched" "Detected in some" 38 "EFO-21: 36.0;HEL: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" 11.3 2.3 0.2 11.9 0.6 2.2 10.6 0.0 0.6 8.9 3.7 3.3 5.1 6.4 4.1 5.1 6.7 9.5 6.7 0.3 0.0 5.6 2.5 12.6 7.0 0.2 0.2 1.8 1.2 3.1 2.2 6.3 0.2 6.1 4.1 0.0 2.7 5.7 1.0 3.6 4.8 14.2 0.1 1.0 2.8 0.7 0.7 2.6 4.0 1.8 12.6 14.4 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.4 0.6 0.0 0.2 0.0 1.1 0.5 0.2 0.0 0.1 0.2 0.1 2.1 0.3 0.0 0.1 8.8 7.8 0.2 0.6 0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.1 0.7 0.2 14.7 0.0 3.6 0.3 0.4 3.7 0.1 0.0 0.6 0.0 0.2 0.1 1.9 1.5 0.0 1.8 0.0 2.6 0.1 0.0 0.0 0.0 2.0 0.1 0.1 51.8 0.0 5.2 0.5 0.2 0.0 1.5 0.0 0.0 0.0 0.0 33.9 0.4 0.2 0.0 0.2 0.0 0.0 1.5 3.6 0.1 0.3 10.1 3.6 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.1 3.4 4.1 0.5 0.0 0.0 0.3 SEMA3B "LUCA-1, SemA, sema5, SEMAA, semaV" ENSG00000012171 "Semaphorin 3B" Q13214 3 50267558-50277546 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 174.5;brain: 184.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.5;Distal enterocytes: 129.1;Gastric mucus-secreting cells: 208.0;Oligodendrocytes: 157.8;Proximal enterocytes: 336.4;Syncytiotrophoblasts: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 73.7;Hep G2: 105.7;SK-BR-3: 54.5;WM-115: 173.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 27.9" HPA030651 Uncertain "Secreted in other tissues" NA NA 790000 "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" "HPA030651: AB_10602224" "prognostic favorable (1.27e-4)" "unprognostic (6.48e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (4.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.28e-1)" "unprognostic (1.85e-2)" "unprognostic (4.27e-1)" "unprognostic (7.99e-2)" "unprognostic (7.78e-2)" "unprognostic (3.89e-1)" "unprognostic (8.87e-3)" "unprognostic (1.69e-2)" 33.6 174.5 50.2 9.0 124.4 0.2 17.3 87.7 78.2 46.2 35.2 53.6 41.3 45.7 2.2 9.1 37.0 10.0 40.3 53.1 66.4 70.9 6.1 49.2 0.3 125.7 101.9 24.5 41.4 10.6 10.4 35.3 98.6 34.0 10.5 2.0 12.7 20.6 7.4 7.9 62.8 14.2 76.2 5.1 56.8 14.8 110.4 0.6 24.2 8.7 0.3 19.6 32.3 184.2 12.7 8.2 0.8 8.0 0.6 1.0 2.0 16.3 22.3 4.7 7.9 5.5 29.7 0.0 14.3 15.3 0.0 1.8 0.4 26.2 1.8 0.2 0.7 0.0 73.7 105.7 16.8 0.0 0.8 5.1 0.5 5.4 4.1 19.9 0.0 0.1 0.2 2.2 0.8 22.4 0.0 0.7 1.1 23.4 4.5 0.3 1.2 0.6 7.4 1.4 1.0 3.8 4.2 54.5 9.2 2.4 3.6 0.1 0.5 1.3 15.4 4.3 5.3 4.4 0.2 0.2 7.9 0.2 173.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.2 124.4 87.7 78.2 53.1 66.4 125.7 101.9 98.6 76.2 110.4 184.2 6.5 163.5 18.6 45.1 1.8 0.0 8.3 0.0 6.2 3.7 19.3 8.5 14.5 44.3 18.6 64.4 0.0 3.6 1.2 129.1 1.9 38.3 11.2 29.8 11.6 6.1 10.3 0.0 0.6 23.1 1.0 35.3 208.0 73.1 11.4 11.4 5.7 1.2 1.9 0.0 0.8 45.7 0.0 1.6 0.0 21.4 4.1 2.8 0.0 12.2 0.7 17.3 0.0 3.0 157.8 32.5 79.9 3.0 0.6 14.1 336.4 40.4 5.1 1.6 6.6 19.0 7.5 6.6 11.4 2.0 0.0 111.6 2.4 0.2 31.5 32.7 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 45 "liver: 34022.4" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 42919.3" "Cancer enriched" "Detected in all" 10 "liver cancer: 3850.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2482.1;intermediate monocyte: 3411.9;neutrophil: 2823.2;non-classical monocyte: 4518.8" "Group enriched" "Detected in all" 5 "granulocytes: 2823.2;monocytes: 4518.8" "Cell line enriched" "Detected in many" 10 "Hep G2: 4769.1" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "cerebellum: 130.6" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 2070000000000 140000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB013211: , CAB016648: AB_1611888, CAB073396: , HPA000927: AB_1844761, HPA001292: AB_1844762" "prognostic favorable (1.61e-5)" "unprognostic (3.37e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.50e-3)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.96e-1)" 49.1 9.7 7.3 225.0 7.1 157.1 100.6 9.1 21.3 105.7 11.1 151.0 278.6 42.3 5.3 10.1 22.4 352.3 12.5 7.3 11.1 621.2 34022.4 570.7 37.0 20.9 14.4 5.4 201.0 5.2 9.1 26.6 15.8 12.6 178.8 2.6 33.6 140.5 3.7 8.2 760.9 75.7 12.2 313.6 282.5 3.0 16.2 15.0 23.0 11.9 25.2 55.8 9.1 16.9 25.9 0.3 0.0 0.5 1.0 0.0 1.5 0.6 1.7 0.6 1.1 187.8 500.8 2.6 15.6 0.0 1.4 1.9 0.0 10.9 1.2 70.1 0.0 4.3 2.0 4769.1 0.3 16.8 2.3 4.1 5.4 0.3 18.5 1.9 0.0 0.0 3.2 0.4 0.0 0.8 1.1 12.1 2.0 5.5 8.0 1.9 16.7 2.4 300.8 3.0 0.6 1.3 6.4 1.6 1.4 0.4 262.1 2.7 1.6 2.1 59.4 1.9 7.1 3.3 1.8 7.0 4.4 41.8 0.6 10.6 2482.1 634.3 5.5 3411.9 6.8 7.7 3.6 4.1 683.6 3.6 4.3 3.6 2823.2 5.3 4518.8 14.9 4.5 2770.7 7.3 7.1 9.1 21.3 7.3 11.1 20.9 14.4 15.8 12.2 16.2 16.9 2.2 35.3 285.9 0.0 137.4 2.3 1.0 36.3 0.0 0.2 100.8 31.5 5.3 4520.9 165.5 150.8 0.0 1.6 3.9 52.0 68.4 3787.9 0.2 70.0 2.8 57.0 12.1 1227.4 0.0 225.8 4.5 3.6 36.2 51.3 1.3 0.1 938.8 42919.3 167.6 0.0 0.0 742.4 30.5 1454.0 74.1 1.1 0.0 413.3 1.8 1.0 291.7 0.3 9.2 0.0 0.0 2161.6 137.0 0.0 1.5 6.8 5270.0 745.9 108.3 0.2 0.0 0.6 17.4 0.0 0.2 0.6 1.7 6.4 75.5 0.0 83.2 6.7 SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 9176.5;pancreas: 4910.2" "Cell type enhanced" "Detected in some" "Ductal cells: 20.9;Exocrine glandular cells: 33.0;Fibroblasts: 68.6;Late spermatids: 12.2;Pancreatic endocrine cells: 18.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "Hep G2: 449.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" NA NA 697000000000 94000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" 91.8 58.0 100.4 43.4 116.5 2.1 371.0 117.7 293.8 368.8 110.3 79.5 11.7 44.9 11.5 42.5 116.6 146.0 311.7 103.6 320.0 215.5 9176.5 169.9 5.0 196.3 183.1 181.5 4910.2 1.0 271.2 14.6 138.3 580.5 13.3 131.5 1505.8 54.9 177.8 55.7 91.6 83.1 141.4 31.7 290.5 66.9 176.3 2.6 72.6 38.9 6.4 207.4 70.4 173.0 0.2 0.5 0.0 0.3 0.2 0.8 0.3 0.1 0.1 0.0 0.0 1.2 4.9 0.6 4.5 0.0 3.3 0.9 0.0 4.4 0.0 2.7 0.0 1.0 0.2 449.9 56.9 1.9 0.7 52.0 63.9 0.0 2.5 5.4 0.0 0.0 0.3 0.2 0.0 17.1 0.5 0.5 0.8 1.6 0.0 0.6 2.2 0.2 3.8 0.2 0.1 0.0 1.8 2.5 65.6 0.4 2.4 0.0 0.6 0.0 8.5 0.1 19.4 1.1 2.0 2.1 0.4 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 116.5 117.7 293.8 103.6 320.0 196.3 183.1 138.3 141.4 176.3 173.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.5 1.8 0.0 5.6 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 20.9 3.7 0.2 0.1 0.3 0.0 0.0 0.0 33.0 0.0 68.6 9.7 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.3 0.0 0.0 1.0 0.2 0.0 0.0 0.0 18.7 0.0 0.4 0.3 0.5 0.0 0.1 1.5 0.0 0.0 1.7 0.8 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 400.4;Endometrial ciliated cells: 175.2;Glandular and luminal cells: 345.3;Hepatocytes: 198.2;Late spermatids: 277.8;Peritubular cells: 144.4" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" 5.1 484.5 1.8 3.3 2.4 0.0 19.6 2.2 1.7 29.6 3.0 5.3 5.5 31.8 1.2 0.8 26.3 160.5 19.0 1.6 7.2 151.4 785.6 1.0 3.6 3.5 3.8 30.1 173.9 0.2 3.2 0.1 5.3 6.8 1.9 14.0 9.4 153.3 46.4 3.3 3.6 2.1 1.7 112.2 12.1 432.4 2.8 0.9 4.1 152.6 4.7 2.3 4.0 3.7 0.8 0.1 2.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 12.0 12.2 0.0 8.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 261.3 0.3 0.4 0.0 1.7 0.3 0.1 0.0 2.3 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.5 0.2 3.9 0.1 0.4 17.4 0.2 0.1 7.9 0.9 0.1 0.0 0.5 0.0 0.6 0.4 1.5 0.2 0.1 0.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 2.2 1.7 1.6 7.2 3.5 3.8 5.3 1.7 2.8 3.7 0.9 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.2 18.9 14.1 0.8 400.4 0.1 33.1 2.1 0.0 0.1 0.0 64.6 103.2 78.7 175.2 19.7 40.3 0.0 2.7 0.0 122.2 0.0 18.2 0.5 345.3 0.0 78.2 2.5 198.2 0.0 8.4 0.0 0.0 0.0 3.2 0.7 277.8 57.2 1.9 0.0 0.0 0.6 5.4 0.0 0.0 0.2 18.3 0.0 144.4 0.0 0.1 0.0 7.5 0.0 1.4 6.6 11.6 1.5 11.1 2.9 0.0 0.6 0.3 1.8 58.7 0.0 0.1 SERPINB13 "headpin, HUR7, hurpin, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 56.6;esophagus: 180.4;vagina: 135.0" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 58.8;Club cells: 54.8;Squamous epithelial cells: 148.6" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 129 "HaCaT: 198.9;hTCEpi: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 56.6 0.0 0.0 0.0 0.0 0.0 180.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 35.7 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 22.9 3.3 135.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 1.7 1.9 58.8 13.1 0.0 0.0 0.1 0.1 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 8.5 0.0 0.0 0.0 1.0 0.0 0.0 148.6 1.3 0.5 0.0 0.0 0.0 19.9 SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.9;Suprabasal keratinocytes: 1053.6;Syncytiotrophoblasts: 439.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cell line enhanced" "Detected in many" "GAMG: 282.7;HaCaT: 699.1;U-138 MG: 807.0;U-2197: 1243.9" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" 21.0 0.3 0.0 8.6 0.0 36.5 8.7 0.0 1.3 21.0 0.0 0.5 0.1 0.7 0.0 239.1 8.4 0.7 1.0 0.0 0.2 0.2 0.3 2.8 0.0 0.0 0.1 0.3 1.1 0.2 0.1 50.1 0.0 0.2 0.0 0.0 31.2 0.0 0.3 89.2 0.1 1.7 0.0 0.3 0.8 0.0 1.1 2.6 0.1 0.2 81.2 6.6 45.4 0.0 1.4 0.0 0.0 0.8 1.3 0.6 0.2 169.2 179.2 6.0 13.1 0.9 0.4 0.2 0.0 6.1 282.7 699.1 0.0 143.7 118.6 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.5 1.5 13.9 81.7 37.0 1.8 0.6 0.0 0.6 0.4 2.8 0.0 0.2 0.4 0.3 0.2 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 1.1 0.0 0.6 0.7 15.7 13.9 807.0 0.4 1243.9 0.0 0.2 0.1 0.0 21.6 1.8 96.7 22.0 4.9 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.5 0.0 0.2 2243.9 4.1 82.1 0.0 0.0 0.6 0.1 0.7 0.0 153.4 0.0 0.0 6.2 0.1 0.0 0.0 92.6 0.0 0.1 0.1 5.5 0.0 0.0 0.0 7.1 1.7 11.0 0.0 0.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 26.4 2.9 86.4 0.0 0.0 73.1 94.3 0.0 3.9 0.0 0.0 0.0 0.0 167.2 0.0 0.0 1.0 18.9 0.0 0.0 94.5 0.0 0.0 0.3 14.8 0.0 0.0 94.7 1053.6 439.3 2.5 0.0 0.0 52.0 SERPINB3 "HsT1196, SCC, SCCA1, T4-A" ENSG00000057149 "Serpin family B member 3" P29508 18 63655197-63661893 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 418.5;esophagus: 809.7;vagina: 669.6" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 6903.4;Club cells: 6726.1" "Group enriched" "Detected in many" 4 "cervical cancer: 186.5;head and neck cancer: 69.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.9;HaCaT: 6.5;HBEC3-KT: 1.6;SiHa: 4.1;U-2197: 8.2" "CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992" Enhanced Approved "Plasma membrane,Cytosol" NA NA 9100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB018772: AB_2285759, CAB036006: , CAB036007: , HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (2.95e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (4.19e-3)" 0.1 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 418.5 0.0 0.1 0.0 3.2 0.0 809.7 0.2 0.2 0.4 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.0 7.6 0.0 0.0 100.0 0.0 0.1 42.9 0.1 0.0 0.0 0.1 0.5 1.9 0.0 4.8 0.1 0.0 19.6 73.8 669.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.1 6.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 35.2 6903.4 2.2 0.0 0.0 0.0 0.0 0.0 6726.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 31.4 0.1 0.2 0.5 0.0 0.0 0.0 8.9 0.0 3.0 0.0 0.9 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 986.7 0.0 0.0 55.4 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.4 0.0 60.2 0.0 0.2 447.6 0.0 0.0 0.0 178.1 1.0 0.3 413.5 0.0 0.3 0.8 0.0 0.0 265.9 SERPINB4 "LEUPIN, PI11, SCCA-2, SCCA1, SCCA2" ENSG00000206073 "Serpin family B member 4" P48594 18 63637259-63644256 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 78.6;esophagus: 93.3;vagina: 150.9" "Cell type enriched" "Detected in some" 4 "Basal respiratory cells: 3577.0" "Group enriched" "Detected in many" 5 "cervical cancer: 104.1;head and neck cancer: 29.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.2;HSkMC: 1.1;SiHa: 1.7;U-2197: 6.1" "HPA048341, HPA049988, HPA055992" Supported NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (8.81e-3)" "unprognostic (9.43e-2)" "unprognostic (8.96e-3)" "unprognostic (4.38e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (2.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.27e-2)" 0.1 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 78.6 0.0 0.0 0.0 0.6 0.0 93.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 0.0 23.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.0 0.0 4.5 21.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 3577.0 0.0 0.0 0.0 0.0 0.0 0.0 825.8 0.0 0.0 0.0 0.0 0.0 0.0 23.9 1.4 0.1 0.1 0.2 0.0 0.0 0.0 21.7 0.2 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 97.6 0.0 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 32.4 0.0 0.3 53.0 0.0 0.0 0.0 10.7 0.1 0.0 14.8 0.0 0.8 0.0 0.0 0.0 60.5 SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 418.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 165.1;Fibroblasts: 162.1;Pancreatic endocrine cells: 231.8;Smooth muscle cells: 239.3;Syncytiotrophoblasts: 651.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 20 "NK-cells: 9.5" "Cell line enhanced" "Detected in many" "BJ: 3483.8;HUVEC TERT2: 4014.7;LHCN-M2: 3874.5;TIME: 10032.6;U-138 MG: 4609.6;U-251 MG: 4256.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA050039, CAB068501" Uncertain Approved Cytosol "Secreted to blood" No No 142000000 13000000 "Cluster 22: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB068501: AB_1642775, HPA050039: AB_2680997" "unprognostic (5.02e-2)" "prognostic unfavorable (5.01e-4)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.10e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (2.84e-5)" "unprognostic (6.80e-3)" "prognostic unfavorable (4.41e-6)" "unprognostic (2.33e-1)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.88e-8)" "prognostic unfavorable (3.27e-6)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.51e-4)" 215.5 75.3 3.1 91.6 3.4 1.7 56.2 5.2 12.8 62.1 5.0 31.7 7.4 31.1 1.0 16.4 41.3 360.3 136.0 3.9 6.6 166.2 345.8 260.2 21.3 6.4 3.7 105.6 135.1 11.8 12.3 418.0 4.5 37.8 5.4 4.9 10.6 8.0 17.8 21.2 13.1 74.3 4.8 13.8 30.3 5.5 12.7 6.7 59.5 4.3 3.5 359.9 19.2 6.0 77.3 64.4 1.2 5.1 766.6 1511.0 89.3 3483.8 654.6 1717.6 1487.4 9.4 5.5 2.7 812.6 1117.9 2367.3 18.1 0.4 269.4 1756.2 4.3 0.7 1.1 5.2 61.4 1532.6 0.2 3.8 596.1 106.9 2641.4 1374.8 928.5 4014.7 0.2 6.4 2.5 3874.5 0.4 0.6 2.2 18.2 1.3 41.7 0.6 6.1 4.8 5.1 30.3 1.0 0.8 286.3 77.2 8.3 410.9 3.3 9.9 10032.6 4609.6 204.0 1593.8 4256.0 0.6 2.9 4.2 1150.5 2.4 45.9 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 9.5 0.0 0.3 0.0 0.8 3.1 3.4 5.2 12.8 3.9 6.6 6.4 3.7 4.5 4.8 12.7 6.0 35.8 0.0 7.7 0.0 1.1 40.0 43.7 97.4 14.2 0.3 0.3 2.3 2.5 4.3 11.0 5.5 0.0 56.0 1.0 0.4 0.0 65.1 0.0 4.7 53.8 165.1 5.3 0.0 0.5 4.5 75.1 162.1 0.5 3.2 10.2 12.4 40.4 112.3 15.9 0.0 0.3 0.2 8.2 4.6 9.6 1.1 17.7 11.1 7.2 5.6 1.1 0.7 0.0 0.0 0.0 231.8 0.0 12.0 3.6 9.7 0.1 0.0 8.2 0.3 39.5 55.4 239.3 0.0 0.1 9.0 24.7 651.7 2.3 2.1 0.5 8.1 SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1875.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 697.8;Cytotrophoblasts: 795.6;Fibroblasts: 951.9;Hepatocytes: 765.0;Leydig cells: 1818.0;Peritubular cells: 1045.7" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enhanced" "Detected in many" "hippocampal formation: 85.4" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1454.4" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1454.4" "Group enriched" "Detected in many" 4 "ASC diff: 1232.0;ASC TERT1: 956.3;Hep G2: 606.0;HHSteC: 410.6;HSkMC: 1313.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" NA NA 9290000000 44000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" 535.5 57.5 5.7 124.2 9.6 11.9 490.2 17.9 28.0 558.7 1875.2 131.3 41.9 358.2 90.2 109.3 557.4 559.7 376.5 85.4 1.1 35.1 974.8 158.9 133.5 0.1 5.1 408.3 207.6 11.2 62.4 311.6 1.3 202.8 52.0 61.4 124.6 105.8 434.8 162.9 131.7 221.7 2.8 133.2 124.7 277.7 25.4 106.2 193.1 465.5 117.7 323.4 273.5 7.0 0.5 3.7 2.8 2.0 1232.0 956.3 20.4 56.8 49.8 0.6 0.0 9.7 0.5 2.3 1.9 71.8 0.3 3.2 86.0 4.4 0.0 0.6 46.0 1.0 1.2 606.0 410.6 1.1 1.1 1313.4 6.9 0.9 1.1 11.4 0.6 4.2 117.5 0.4 63.2 0.2 7.0 7.2 30.7 0.3 1.0 2.9 219.9 1.6 0.1 6.0 1.9 42.2 0.7 0.7 57.0 3.4 6.7 184.2 2.0 0.5 17.6 14.1 1.2 0.7 2.4 28.1 1.7 0.6 0.8 0.1 12.0 1.1 0.6 4.4 0.4 9.0 0.7 0.9 79.8 5.2 2.0 5.5 1.7 1.3 0.2 1454.4 0.8 14.2 5.7 9.6 17.9 28.0 85.4 1.1 0.1 5.1 1.3 2.8 25.4 7.0 59.0 3.2 10.4 0.3 10.8 95.0 238.0 697.8 27.9 59.3 6.7 71.2 12.1 11.5 167.7 1.8 223.1 795.6 226.1 0.0 0.0 0.3 11.2 12.5 372.4 26.2 0.0 19.2 5.3 24.5 98.7 951.9 11.2 6.7 22.9 1.7 28.2 765.0 151.6 3.3 2.6 0.0 366.2 60.4 262.6 53.0 1818.0 79.0 108.5 9.4 79.0 11.6 1.0 0.5 2.0 6.8 0.1 1045.7 7.0 155.5 0.2 27.3 105.5 39.1 19.7 193.3 202.8 12.7 8.7 4.5 78.6 534.8 14.3 10.2 0.3 47.7 SET "2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA" ENSG00000119335 "SET nuclear proto-oncogene" Q01105 9 128683424-128696400 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005232, HPA063683" Supported Enhanced "Nucleoplasm,Lipid droplets" NA NA 880000 "Cluster 49: Eosinophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Lipid droplets" "CAB005232: AB_2185634, HPA063683: AB_2685088" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (2.31e-1)" "unprognostic (3.77e-1)" "unprognostic (7.15e-2)" "unprognostic (4.37e-3)" "prognostic unfavorable (9.41e-7)" "unprognostic (2.00e-2)" "unprognostic (1.88e-2)" "unprognostic (3.62e-1)" "unprognostic (3.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (7.57e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (1.54e-2)" 124.9 122.7 125.2 195.6 134.6 261.8 174.2 115.9 137.6 147.7 111.0 160.1 125.5 174.7 88.0 196.3 154.9 149.1 152.7 109.1 115.3 155.5 159.8 129.3 308.5 120.3 126.1 190.6 175.3 143.3 78.6 206.2 126.9 135.8 169.7 142.4 139.4 134.9 182.5 154.1 132.2 164.6 141.1 170.4 139.8 105.3 124.2 286.8 211.2 134.5 300.4 220.8 122.9 147.6 579.4 644.4 908.7 723.6 265.2 412.2 835.7 465.8 511.8 656.9 449.9 892.0 688.8 1483.4 383.1 482.8 513.6 1053.0 1358.8 700.1 745.2 681.2 577.8 855.2 968.5 734.5 591.3 1581.1 535.5 346.7 535.7 561.6 1114.6 526.1 626.1 781.8 1692.1 583.3 545.4 974.2 1333.9 580.0 1521.8 876.7 678.6 1198.7 1128.2 1198.7 506.5 640.5 921.0 576.5 1024.4 679.0 560.5 641.6 847.6 483.9 604.4 770.6 576.9 481.4 784.1 455.0 1417.0 1737.1 367.1 824.8 753.1 165.1 207.3 182.0 224.0 235.4 277.6 287.4 253.0 240.4 215.1 258.0 241.0 286.1 141.4 329.2 199.5 271.6 223.1 335.1 125.2 134.6 115.9 137.6 109.1 115.3 120.3 126.1 126.9 141.1 124.2 147.6 249.9 121.8 145.0 25.1 337.1 673.6 507.5 134.0 352.8 187.6 372.3 250.6 204.2 238.8 134.0 196.8 43.8 316.7 365.9 136.8 389.4 254.6 43.5 318.3 502.1 266.9 256.1 355.6 41.7 218.7 504.0 194.8 126.9 438.5 132.3 308.3 193.1 198.5 239.4 124.5 40.2 261.8 93.6 264.0 436.5 33.6 164.1 249.0 327.3 22.5 274.3 240.6 211.2 38.2 36.6 294.5 132.5 173.4 356.2 647.6 106.7 338.6 87.0 132.5 131.5 323.9 297.0 124.6 259.7 448.0 702.1 314.5 292.3 238.9 342.8 580.9 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SETD2 "FLJ23184, HIF-1, HYPB, KIAA1732, KMT3A" ENSG00000181555 "SET domain containing 2, histone lysine methyltransferase" Q9BYW2 3 47016429-47164113 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Differentiation, DNA damage, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042451 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" Cytosol "HPA042451: AB_10806239" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (6.08e-2)" "unprognostic (1.01e-1)" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.19e-2)" "unprognostic (2.45e-1)" "unprognostic (7.84e-2)" "prognostic favorable (7.99e-6)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (8.79e-2)" "unprognostic (5.43e-2)" 9.9 6.5 8.2 10.7 10.5 23.8 10.3 24.1 8.3 12.6 10.8 9.7 9.1 13.3 6.1 9.8 11.0 8.5 7.2 6.2 6.7 10.8 10.0 9.4 13.5 8.3 8.5 15.3 13.3 16.2 2.2 11.4 8.4 10.2 11.0 10.6 9.6 9.7 11.1 9.0 10.3 11.9 8.1 11.4 10.7 13.1 7.9 19.2 15.5 14.5 13.3 9.8 4.0 12.8 21.1 13.2 25.4 14.5 15.3 18.9 11.3 17.9 17.0 20.8 19.9 15.4 13.8 43.5 11.6 25.5 20.0 12.4 29.5 17.6 27.6 27.5 12.2 47.3 24.8 12.4 11.7 34.1 26.5 15.2 17.3 20.7 24.6 15.3 20.1 22.8 29.9 16.6 17.8 9.5 26.7 8.5 20.6 9.4 15.4 17.5 25.6 23.2 12.4 26.6 10.9 17.6 29.5 11.8 12.0 17.2 12.9 27.5 26.7 24.6 18.1 21.5 29.9 22.0 25.4 43.7 14.2 19.6 14.6 1.3 1.2 2.9 2.0 1.1 1.1 2.2 1.2 1.6 1.4 2.5 1.7 1.6 3.3 3.6 1.1 1.5 0.6 0.6 8.2 10.5 24.1 8.3 6.2 6.7 8.3 8.5 8.4 8.1 7.9 12.8 50.5 48.1 58.8 115.9 58.3 33.3 22.6 15.6 54.1 40.5 31.0 29.1 67.2 27.1 53.2 11.0 41.7 20.3 58.2 32.6 11.7 20.9 26.1 62.8 63.0 41.2 22.1 38.9 131.4 22.4 12.7 39.2 56.6 66.2 58.8 68.9 23.6 29.8 16.8 26.9 129.4 28.2 14.2 28.8 26.5 35.1 30.4 42.7 17.8 148.9 37.9 22.7 43.3 113.1 143.2 23.7 22.3 33.1 54.0 31.2 24.6 11.5 49.7 39.9 13.1 56.1 42.6 71.0 29.3 60.2 35.7 18.5 65.3 57.1 29.5 34.7 SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated histone lysine methyltransferase 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "U-698: 341.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "HPA018142: AB_1856757, HPA058484: AB_2683731" "unprognostic (1.07e-1)" "unprognostic (4.08e-1)" "unprognostic (8.02e-2)" "unprognostic (2.24e-3)" "unprognostic (1.65e-2)" "unprognostic (9.57e-2)" "prognostic unfavorable (8.88e-4)" "unprognostic (6.03e-2)" "unprognostic (9.94e-3)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (6.65e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" 13.5 11.3 7.1 15.2 8.2 18.1 16.7 12.8 8.9 14.4 8.7 13.4 12.5 18.1 13.1 11.8 15.3 11.5 8.2 6.7 7.9 11.7 11.5 13.4 19.6 8.2 7.6 19.4 13.3 15.7 8.6 17.7 7.6 11.4 15.5 14.2 12.3 12.2 16.4 14.4 13.7 16.5 6.0 19.9 13.4 25.1 8.4 21.6 15.5 11.7 20.3 13.1 12.7 10.3 22.9 26.3 37.1 24.6 17.5 23.2 61.7 18.6 21.2 26.2 22.2 17.9 31.1 44.9 24.9 20.7 10.4 28.1 35.0 20.0 20.7 21.8 43.3 25.5 27.3 20.8 24.7 45.3 23.2 30.5 22.0 21.8 34.8 26.6 31.2 28.3 43.4 35.6 18.9 44.1 31.6 26.4 51.1 32.1 20.6 36.3 24.3 33.4 20.1 25.9 27.1 49.1 28.4 32.9 22.5 44.5 35.7 60.4 21.2 15.3 15.7 17.0 26.3 36.6 42.3 341.6 15.7 15.7 15.1 6.9 8.3 5.7 5.8 11.6 6.1 6.1 5.3 6.6 9.7 8.3 5.7 5.9 4.8 6.3 8.5 6.5 3.5 4.3 7.1 8.2 12.8 8.9 6.7 7.9 8.2 7.6 7.6 6.0 8.4 10.3 8.5 6.4 14.0 15.3 15.3 5.5 9.3 6.6 10.2 11.0 9.8 10.7 5.5 10.0 7.8 7.3 18.8 13.9 8.8 6.6 3.9 7.6 26.1 10.8 13.3 8.3 3.6 9.2 19.6 5.7 8.5 9.1 10.2 10.7 7.6 17.9 11.4 8.1 9.9 6.7 19.4 9.7 12.2 17.2 5.1 31.0 10.2 13.9 1.8 23.4 14.4 6.2 14.4 15.6 23.5 8.1 9.5 9.8 8.9 8.2 7.6 6.4 11.0 10.4 6.6 10.2 10.3 24.4 15.9 10.9 5.1 10.0 10.2 14.6 10.7 7.8 SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 94000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA050275: AB_2681071" "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" 183.8 173.9 101.7 132.7 112.4 304.8 180.7 120.5 126.1 222.8 136.8 170.9 110.4 195.8 200.0 136.8 183.8 123.2 135.7 98.2 100.8 135.4 168.5 162.8 203.0 105.7 101.9 226.5 200.7 154.9 147.8 165.3 111.0 163.2 147.3 138.4 180.4 133.2 172.4 156.5 231.6 116.5 107.5 287.8 169.2 91.4 104.9 221.9 167.8 144.8 199.3 154.4 167.1 135.8 134.9 105.4 288.6 155.9 222.8 219.2 237.8 172.6 196.7 163.2 205.9 233.0 147.2 247.5 116.6 193.1 165.8 133.7 273.4 151.2 271.8 196.5 154.8 237.5 257.4 294.3 155.4 270.1 198.6 232.1 163.0 175.9 209.3 278.6 205.9 171.0 210.2 174.0 192.3 134.2 251.1 285.6 231.4 167.5 163.8 234.4 197.9 182.9 245.8 286.4 154.2 186.7 174.7 118.2 139.2 345.1 115.2 242.5 186.8 126.9 109.4 123.3 145.8 168.7 238.8 342.0 123.7 174.8 146.5 49.8 50.4 57.5 54.5 51.7 55.4 46.1 46.2 50.9 60.5 44.1 48.7 49.2 60.8 56.7 52.5 37.5 71.3 56.2 101.7 112.4 120.5 126.1 98.2 100.8 105.7 101.9 111.0 107.5 104.9 135.8 175.6 179.5 222.9 92.4 187.4 119.0 172.0 127.1 125.7 103.4 96.4 83.3 129.2 72.9 194.0 92.0 73.0 116.8 224.1 90.1 56.7 104.8 9.2 123.9 191.0 143.1 110.5 109.0 55.5 94.8 102.3 151.6 132.0 179.0 246.9 171.1 107.1 74.4 100.6 94.2 59.7 108.1 89.5 124.7 144.1 20.6 120.2 166.1 76.5 75.9 163.9 111.1 116.4 87.0 121.1 112.0 68.3 104.6 195.6 103.8 84.2 70.5 221.5 98.5 118.3 159.5 227.9 104.6 100.5 94.3 118.8 142.7 216.2 119.4 91.4 156.1 SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2461.5;skin 1: 1219.1;vagina: 692.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7750.0;Basal prostatic cells: 2119.7;Squamous epithelial cells: 3587.1;Suprabasal keratinocytes: 10714.0;Urothelial cells: 2780.0" "Cancer enhanced" "Detected in all" "cervical cancer: 1510.8;head and neck cancer: 2526.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cell line enhanced" "Detected in many" "A-431: 770.8;HaCaT: 1181.6;HBEC3-KT: 1819.0;hTCEpi: 1196.7" "Low region specificity" "Detected in many" "CAB006268, HPA011105, CAB040552" Enhanced Supported Cytosol "Secreted in other tissues" NA Yes 29000000 "Cluster 34: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Cytosol "CAB006268: AB_425459, CAB040552: , HPA011105: AB_1844339" "unprognostic (5.70e-2)" "unprognostic (1.26e-1)" "unprognostic (8.37e-2)" "prognostic favorable (1.92e-4)" "unprognostic (1.26e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (1.71e-2)" "unprognostic (2.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (7.45e-6)" "unprognostic (7.90e-3)" "unprognostic (3.25e-1)" "unprognostic (8.12e-2)" "unprognostic (2.06e-2)" 3.1 0.8 1.9 11.6 1.8 2.0 29.1 1.8 9.5 350.2 0.4 95.4 48.8 8.0 0.7 2461.5 2.2 21.4 1.3 1.9 1.6 16.0 3.7 56.1 0.2 9.0 4.4 0.9 2.2 0.1 2.7 1.6 4.3 77.2 32.5 0.6 332.8 3.2 5.0 1219.1 40.8 3.3 1.2 0.9 66.6 0.7 5.2 22.1 2.0 0.1 147.9 167.6 692.0 2.3 770.8 126.9 0.1 1.1 0.3 0.1 37.2 0.5 0.0 0.1 0.3 46.6 393.6 6.7 32.2 0.2 0.6 1181.6 0.3 1819.0 0.0 183.4 5.4 0.9 119.6 138.4 0.1 0.4 1.4 0.4 1196.7 0.6 310.1 0.2 0.2 0.7 1.8 4.5 0.1 163.8 0.7 0.3 2.3 132.6 208.7 0.5 0.4 43.1 281.3 173.9 0.7 0.7 181.2 31.9 1.8 2.9 83.6 1.5 0.5 0.5 337.2 0.3 4.9 1.0 5.8 3.8 1.5 0.7 0.7 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 1.8 1.8 9.5 1.9 1.6 9.0 4.4 4.3 1.2 5.2 2.3 1.6 179.5 162.2 0.0 5.0 7750.0 2119.7 1374.7 1714.2 0.0 72.6 119.9 0.8 24.3 285.6 16.5 0.0 18.6 0.7 972.0 3.9 48.8 0.0 138.0 20.1 45.3 67.4 0.0 0.0 76.2 59.9 46.2 221.2 251.8 32.3 0.0 0.4 4.5 1.9 0.0 0.1 140.7 114.0 0.6 479.7 0.0 0.0 9.7 533.6 0.0 1.0 0.0 0.0 0.0 0.1 524.8 933.0 0.0 21.2 1030.2 318.5 0.6 158.2 0.0 0.0 0.7 55.2 0.0 0.6 3587.1 10714.0 6.0 23.4 0.1 292.4 2780.0 SFPQ "PPP1R140, PSF" ENSG00000116560 "Splicing factor proline and glutamine rich" P23246 1 35176378-35193145 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009886, HPA047513, HPA054689" Enhanced Enhanced Nucleoplasm NA NA 640000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB009886: AB_2186937, HPA047513: AB_2680073, HPA054689: AB_2682574" "prognostic favorable (9.56e-5)" "unprognostic (1.01e-1)" "unprognostic (1.02e-3)" "unprognostic (1.99e-1)" "unprognostic (5.53e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (7.91e-13)" "unprognostic (3.10e-1)" "unprognostic (4.00e-3)" "unprognostic (3.85e-2)" "unprognostic (2.20e-2)" "unprognostic (8.03e-3)" "unprognostic (1.25e-3)" "unprognostic (1.16e-2)" "unprognostic (3.97e-3)" "unprognostic (3.07e-1)" "unprognostic (3.77e-3)" 62.9 46.7 25.1 62.1 26.0 215.1 53.2 38.5 32.3 54.0 23.4 46.9 44.6 60.2 51.0 59.8 54.6 39.9 43.8 24.8 30.7 48.8 50.6 40.8 76.4 30.2 27.2 74.4 52.8 44.9 34.4 51.8 25.2 49.8 54.4 47.4 52.8 35.6 63.9 60.0 47.6 52.9 23.0 54.1 48.0 45.8 24.9 85.5 44.8 27.4 94.5 58.1 52.5 44.6 180.5 147.3 251.1 142.9 60.5 90.0 234.7 96.1 97.1 160.4 116.3 161.5 126.4 325.6 130.1 111.8 100.6 160.4 276.1 188.3 217.0 175.2 183.0 245.5 156.2 193.6 81.5 258.2 140.1 72.4 71.7 139.4 67.3 70.9 142.3 169.1 282.6 150.9 158.3 156.8 304.2 220.1 299.7 107.8 140.7 304.5 170.4 213.6 156.2 214.4 180.1 200.3 138.6 106.3 147.1 174.4 125.0 181.7 152.3 127.7 188.3 84.7 208.9 171.2 156.5 327.6 91.1 168.6 185.9 2.6 4.1 3.0 4.7 5.8 5.4 4.1 4.6 3.8 3.8 4.5 4.3 4.8 2.1 3.4 4.7 7.3 5.6 2.3 25.1 26.0 38.5 32.3 24.8 30.7 30.2 27.2 25.2 23.0 24.9 44.6 286.7 169.9 237.7 149.8 317.4 357.5 239.3 80.6 234.5 230.0 231.6 191.0 149.6 82.9 146.2 110.3 191.8 206.5 339.0 149.7 82.2 120.1 126.8 230.1 318.9 222.2 219.6 198.9 127.3 138.4 222.9 255.8 267.6 333.1 155.8 450.5 123.5 109.1 141.4 171.6 143.4 189.5 59.0 129.4 216.9 361.9 142.9 258.5 140.5 104.9 146.2 152.6 127.7 248.8 183.1 162.0 126.7 116.6 291.8 159.9 94.8 87.6 114.8 223.6 52.6 530.6 259.2 199.1 171.9 287.9 327.3 305.5 313.7 223.7 220.0 167.7 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169246-134318112 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1007.1" "Cell type enhanced" "Detected in many" "Langerhans cells: 1238.4;Proximal enterocytes: 789.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 43.4;eosinophil: 170.2;neutrophil: 91.6" "Group enriched" "Detected in all" 8 "granulocytes: 170.2;monocytes: 43.4" "Cell line enhanced" "Detected in many" "HHSteC: 298.1;RPTEC TERT1: 469.5;SK-MEL-30: 319.7;TIME: 373.9;U-266/84: 358.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: AB_2681407" "unprognostic (2.05e-2)" "prognostic favorable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" 147.5 121.5 35.8 47.4 57.3 68.9 83.2 40.0 51.4 61.1 96.9 68.4 51.4 37.0 9.5 108.4 36.5 170.0 35.8 41.2 42.7 105.2 99.3 81.8 33.6 64.5 44.9 125.8 177.1 1007.1 12.0 70.6 49.6 47.6 39.0 14.1 70.8 60.3 50.2 75.7 282.5 48.4 35.8 21.5 104.2 30.4 53.6 39.7 56.7 33.9 78.1 141.3 96.7 94.0 4.1 6.9 4.2 0.4 51.7 12.9 5.9 76.7 159.4 98.4 79.8 12.2 10.6 13.1 11.3 79.8 48.0 2.5 6.8 12.2 72.0 0.5 3.1 0.6 175.7 9.2 298.1 0.7 6.8 77.3 75.4 96.7 124.3 39.3 167.1 2.3 25.6 192.8 35.6 0.6 1.1 3.0 4.8 20.3 8.3 2.4 8.9 1.5 469.5 1.4 2.2 18.6 241.7 0.7 319.7 43.2 0.5 2.1 373.9 28.8 12.3 176.9 17.1 36.2 358.5 40.3 26.7 12.0 39.5 2.2 43.4 170.2 0.7 24.4 1.6 1.9 1.3 0.8 14.1 1.4 1.6 2.0 91.6 3.6 14.5 0.9 2.5 12.6 35.8 57.3 40.0 51.4 41.2 42.7 64.5 44.9 49.6 35.8 53.6 94.0 346.2 38.5 177.8 34.0 68.0 183.3 133.7 277.3 329.0 12.0 87.1 112.0 28.4 88.6 168.6 68.0 35.5 41.0 27.0 132.2 21.5 81.3 9.6 145.8 73.1 232.1 10.7 14.7 68.2 171.2 33.6 88.8 206.4 483.4 271.8 33.9 353.4 21.9 284.2 0.0 225.7 65.1 91.6 181.3 1238.4 7.7 15.2 492.5 268.6 58.1 29.6 4.6 2.1 270.9 377.7 36.2 123.9 15.8 92.4 51.0 789.1 124.3 61.5 29.3 13.1 43.5 102.9 38.1 10.2 348.1 116.2 579.8 46.9 48.9 36.3 123.8 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 22.2 10.9 10.2 21.9 6.8 60.7 13.3 3.5 9.3 8.6 8.5 11.4 8.1 8.5 3.3 7.7 8.1 18.6 23.4 5.8 6.5 14.3 17.4 20.5 21.0 12.0 7.3 5.5 10.2 5.8 8.0 24.4 10.0 7.3 13.5 3.7 5.3 5.9 9.6 4.1 12.5 13.6 10.1 37.1 7.1 9.5 12.1 10.5 11.1 9.5 15.8 15.7 6.0 14.7 9.2 5.5 7.0 7.3 23.9 35.5 4.8 29.2 79.5 21.9 23.3 8.4 5.2 15.6 20.3 44.6 73.6 1.7 5.5 16.9 35.2 13.3 2.7 53.2 2.6 6.2 23.3 23.5 122.2 21.2 3.8 140.7 12.7 48.4 119.1 12.8 38.9 6.1 80.2 3.2 9.7 46.7 11.0 2.4 21.0 9.5 15.9 10.2 10.5 3.7 4.6 4.9 5.4 0.6 42.2 6.2 3.5 33.4 93.0 20.0 11.3 17.4 48.1 13.9 15.8 17.6 211.6 16.6 165.3 0.9 3.5 1.2 1.2 8.4 1.0 1.5 1.1 1.3 4.8 0.5 0.7 1.0 3.0 1.8 6.6 4.9 0.4 1.8 10.2 6.8 3.5 9.3 5.8 6.5 12.0 7.3 10.0 10.1 12.1 14.7 26.8 3.2 22.0 2.6 26.2 6.8 1.5 4.2 1.2 4.6 4.3 3.8 17.5 4.3 4.3 1.8 2.1 0.4 40.6 15.0 1.9 3.6 13.1 1.0 2.2 39.2 3.5 11.2 11.0 9.0 1.4 8.1 0.5 1.2 38.6 0.8 46.1 11.1 40.4 3.3 7.3 3.0 6.1 113.6 130.9 5.3 2.8 84.1 16.0 38.4 67.1 1.1 18.6 11.1 9.0 7.2 5.9 4.1 4.9 3.0 0.8 1.5 3.5 3.4 0.0 4.0 12.7 12.5 4.5 0.7 4.1 1.0 12.1 4.4 3.2 1.2 SH3GL1 "CNSA1, EEN, MGC111371, SH3D2B, SH3P8" ENSG00000141985 "SH3 domain containing GRB2 like 1, endophilin A2" Q99961 19 4360370-4400547 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021485 Approved Enhanced Cytosol NA NA 390000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA021485: AB_1856816" "unprognostic (1.32e-1)" "prognostic favorable (1.50e-4)" "unprognostic (6.85e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.84e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.36e-8)" "unprognostic (5.48e-3)" "unprognostic (2.45e-1)" "unprognostic (1.02e-3)" "unprognostic (4.10e-2)" 61.1 64.7 25.0 29.4 28.8 54.4 50.0 32.8 38.1 69.8 24.2 41.3 40.9 45.1 8.2 175.8 43.9 25.4 37.6 34.4 20.5 39.2 57.4 43.8 22.8 24.8 22.5 49.0 41.8 10.8 46.8 38.9 23.8 48.8 9.2 7.0 51.8 24.0 21.2 119.8 43.7 20.8 21.1 46.8 35.9 28.1 24.7 16.8 37.1 10.1 19.8 53.0 91.6 28.0 111.3 49.2 50.0 66.8 57.4 89.0 92.2 94.2 80.3 82.2 81.1 77.4 56.8 24.9 39.0 94.1 39.8 89.5 35.6 103.7 21.9 33.1 59.8 30.0 66.5 102.7 82.6 27.2 32.6 75.0 70.9 69.4 42.4 40.6 97.8 23.7 78.9 55.1 67.1 92.6 26.5 28.4 126.0 40.4 54.3 20.8 69.8 43.6 65.8 96.4 49.1 75.7 83.3 81.9 59.3 23.5 56.5 42.5 149.3 78.6 57.1 166.7 97.2 34.8 23.2 26.7 112.9 70.0 110.4 0.8 2.3 3.1 2.7 1.1 2.6 3.7 4.0 3.9 3.0 2.7 2.2 2.5 5.6 2.3 3.4 3.8 4.1 2.3 25.0 28.8 32.8 38.1 34.4 20.5 24.8 22.5 23.8 21.1 24.7 28.0 31.6 9.6 21.5 11.8 15.2 60.8 41.0 43.2 19.4 17.1 17.1 15.7 3.6 11.5 25.1 9.2 6.2 41.2 14.7 23.6 13.7 32.1 7.2 17.9 33.8 30.7 10.2 30.7 23.4 29.3 153.7 37.5 19.9 29.5 9.5 23.4 32.9 27.3 51.5 10.1 14.0 18.6 20.3 19.4 51.8 6.7 32.6 22.3 23.2 14.0 14.7 20.3 15.5 12.5 10.3 50.4 17.0 24.0 16.4 38.0 61.6 22.9 15.4 8.7 13.1 17.2 29.3 15.7 11.5 36.8 85.8 44.2 15.1 50.1 19.8 67.1 SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 63.4" "Cell type enhanced" "Detected in some" "Early spermatids: 51.6;Late spermatids: 124.5;Proximal enterocytes: 31.1" "Cancer enriched" "Detected in some" 28 "liver cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.4;Hep G2: 3.0;HSkMC: 4.3" "Not detected" "Not detected" "Secreted to blood" NA NA 9100000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.35e-3)" "unprognostic (6.47e-2)" "unprognostic (5.65e-2)" "unprognostic (2.35e-1)" "unprognostic (8.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.50e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.32e-3)" "unprognostic (3.58e-3)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (7.83e-3)" "unprognostic (4.35e-1)" "unprognostic (5.50e-3)" "unprognostic (1.06e-1)" 0.7 1.3 1.8 0.0 1.8 0.1 0.4 1.7 2.0 0.7 1.9 0.3 5.3 0.5 0.9 0.2 0.6 0.3 0.6 1.9 1.8 3.5 63.4 0.3 0.1 1.8 1.8 0.7 0.4 0.5 0.7 0.3 1.9 0.5 0.2 0.9 0.2 0.4 0.8 0.1 7.1 0.2 1.7 0.4 0.3 12.4 1.7 0.2 0.8 0.7 0.1 0.3 0.2 1.8 0.1 2.4 2.4 0.3 4.4 2.0 0.1 0.6 0.9 0.9 0.5 0.9 0.3 0.0 0.5 0.8 1.2 0.3 0.1 0.1 0.5 0.1 0.3 0.0 0.6 3.0 1.4 0.0 0.1 4.3 0.3 1.6 0.8 0.8 0.1 0.0 0.2 0.1 0.2 0.5 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.3 0.3 0.3 0.1 0.3 1.8 0.0 0.2 0.8 0.4 0.0 0.8 0.4 0.0 0.0 0.2 0.3 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.7 2.0 1.9 1.8 1.8 1.8 1.9 1.7 1.7 1.8 0.2 0.0 0.0 0.7 0.5 0.0 0.3 0.1 0.0 0.4 0.5 0.6 0.5 0.0 0.2 0.0 0.0 0.4 0.0 0.2 5.9 0.5 51.6 0.4 0.6 0.1 0.0 0.0 1.0 0.2 0.1 0.4 0.0 0.2 0.0 0.6 1.1 13.8 0.3 0.0 0.9 1.3 2.0 0.8 0.0 124.5 0.9 0.5 0.0 0.0 0.0 2.4 0.0 0.5 0.6 0.1 1.3 0.7 0.0 0.3 31.1 12.8 0.4 1.3 6.6 0.2 0.3 7.2 0.8 0.0 0.0 0.3 0.1 1.1 0.5 0.3 SIN3A "DKFZP434K2235, KIAA0700" ENSG00000169375 "SIN3 transcription regulator family member A" Q96ST3 15 75369379-75455842 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004506, HPA047213, HPA062123" Enhanced Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB004506: AB_2187766, HPA047213: AB_2679984, HPA062123: AB_2684689" "unprognostic (1.94e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-1)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (8.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.17e-3)" "unprognostic (7.33e-2)" "unprognostic (2.19e-1)" "unprognostic (1.33e-1)" "unprognostic (3.52e-1)" 19.2 12.4 10.0 19.8 10.9 42.5 18.0 21.0 11.7 21.0 12.5 19.6 13.8 25.6 16.6 19.1 24.3 17.4 14.8 9.6 13.3 15.1 16.0 18.0 25.9 11.7 12.0 30.0 15.3 22.5 12.1 20.1 10.3 19.7 16.1 24.1 16.6 20.7 16.6 21.5 16.3 19.6 8.3 22.1 16.5 29.6 14.0 43.2 27.2 18.7 26.3 20.2 16.7 10.8 31.2 63.6 55.5 36.7 27.0 28.4 32.1 22.9 35.3 33.0 35.2 35.2 41.2 67.8 23.3 34.0 45.0 54.5 81.2 34.4 35.9 55.0 42.1 64.0 46.2 27.9 20.5 61.4 52.5 34.7 26.1 38.5 39.8 34.0 30.0 47.5 51.5 73.2 27.0 36.2 60.7 39.1 54.2 41.3 26.3 60.5 73.3 41.8 23.6 56.4 43.7 43.7 56.6 25.0 31.0 53.0 38.1 47.9 26.4 40.6 54.5 27.2 34.3 49.8 85.0 70.8 24.2 61.2 23.2 2.9 4.2 5.9 6.3 3.8 9.6 7.0 8.1 8.1 5.2 7.7 8.2 7.2 7.3 8.1 7.4 3.5 7.7 5.7 10.0 10.9 21.0 11.7 9.6 13.3 11.7 12.0 10.3 8.3 14.0 10.8 26.0 35.3 32.4 13.7 35.8 39.4 23.6 21.2 60.9 19.7 36.5 25.4 13.4 17.2 30.5 27.6 31.3 23.5 29.0 17.8 5.9 15.1 10.1 35.7 30.8 32.1 17.3 24.4 19.2 12.8 11.1 24.4 15.3 42.1 29.9 30.1 26.0 17.4 13.2 20.2 18.3 19.0 10.2 21.3 31.7 5.8 23.0 19.5 10.6 27.2 18.8 16.8 24.7 16.6 24.1 14.1 14.0 20.3 33.1 29.8 13.7 9.2 33.4 33.8 13.1 34.7 24.7 42.1 42.7 37.5 53.1 21.9 34.6 21.2 19.2 19.4 SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 302.1;tongue: 218.2" "Cell type enhanced" "Detected in all" "Early spermatids: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004573, HPA011165" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" Nucleoplasm "CAB004573: AB_2188600, HPA011165: AB_1856900" "unprognostic (2.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (7.20e-7)" "unprognostic (3.75e-3)" "unprognostic (1.28e-2)" "unprognostic (2.85e-2)" "unprognostic (2.44e-3)" "unprognostic (2.73e-1)" "unprognostic (4.83e-2)" "unprognostic (2.97e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (3.60e-2)" "unprognostic (1.19e-1)" "unprognostic (8.73e-2)" "unprognostic (1.70e-1)" 43.2 44.0 101.6 11.5 137.5 17.4 39.7 141.1 123.0 41.5 79.4 49.2 12.6 37.2 10.4 42.5 37.2 15.0 76.9 100.7 111.2 35.9 51.5 38.2 13.7 151.0 129.6 49.0 33.4 18.2 31.2 10.5 144.7 32.7 10.2 11.9 41.5 14.9 302.1 48.8 32.4 18.3 121.3 40.1 41.4 43.5 127.6 13.1 34.5 218.2 13.0 41.3 37.8 173.5 16.1 9.8 8.4 20.6 46.7 31.8 5.8 11.3 20.2 17.8 22.7 17.1 10.2 5.4 23.7 21.3 13.2 8.3 14.6 25.1 10.9 25.2 15.6 10.1 10.9 10.9 33.0 7.0 22.4 33.5 29.7 14.4 16.9 21.4 31.9 17.7 10.1 42.0 28.2 8.9 15.4 6.2 1.2 27.6 13.6 19.9 22.8 15.3 14.8 14.9 20.7 9.0 12.9 17.8 13.0 7.0 8.0 19.2 28.9 24.0 5.1 37.2 17.0 16.9 8.8 12.6 18.1 19.0 22.0 48.9 54.7 59.8 44.9 69.1 28.5 24.9 21.9 31.0 42.9 28.9 14.3 23.6 42.7 36.5 56.7 44.0 33.1 51.9 101.6 137.5 141.1 123.0 100.7 111.2 151.0 129.6 144.7 121.3 127.6 173.5 39.5 16.0 19.4 26.1 21.0 51.6 30.3 35.1 35.3 29.7 28.8 29.7 42.1 14.3 27.2 12.9 35.5 36.5 90.8 28.4 37.2 29.0 173.0 24.7 15.4 31.1 17.5 27.1 31.2 17.6 15.2 30.3 44.9 26.5 25.4 29.5 28.5 19.7 66.3 30.3 27.2 24.1 97.6 38.3 51.7 74.8 31.1 37.1 46.2 11.2 20.0 22.6 85.5 76.4 110.8 26.5 23.9 41.0 39.7 14.9 54.0 38.8 30.1 28.2 19.7 113.5 27.9 15.3 7.2 30.1 60.1 42.3 45.8 31.3 18.2 21.5 SIRT4 SIR2L4 ENSG00000089163 "Sirtuin 4" Q9Y6E7 12 120302316-120313249 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "DNA damage" Transferase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029691, HPA029692" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA029691: AB_10600118, HPA029692: AB_10611520" "unprognostic (2.62e-2)" "unprognostic (7.08e-2)" "unprognostic (4.46e-3)" "unprognostic (1.09e-1)" "unprognostic (1.51e-1)" "unprognostic (2.35e-2)" "unprognostic (2.37e-2)" "unprognostic (4.53e-2)" "unprognostic (1.25e-1)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (1.54e-1)" "prognostic favorable (1.75e-4)" "unprognostic (4.97e-2)" "unprognostic (2.11e-1)" "unprognostic (9.74e-3)" "unprognostic (2.31e-1)" 0.9 3.9 2.9 1.0 2.6 0.3 1.1 3.7 3.2 1.9 3.1 2.8 3.5 2.0 0.8 1.4 1.4 1.2 4.5 2.8 2.5 3.2 3.9 1.6 1.4 2.8 2.5 2.5 1.9 2.8 0.9 0.9 2.8 1.3 1.0 3.7 3.0 1.5 9.8 3.1 1.6 1.8 2.3 1.5 2.2 6.2 2.6 2.2 1.8 7.2 1.0 1.5 1.3 2.9 0.6 1.4 1.9 0.9 5.9 1.9 0.9 1.4 1.6 1.1 2.9 1.5 0.9 1.0 1.6 0.8 1.5 0.3 1.9 0.7 1.9 2.0 2.5 0.0 0.3 1.2 1.4 1.1 0.5 1.7 1.6 0.6 0.4 3.2 1.5 2.8 2.0 0.1 1.7 0.8 1.9 1.6 1.1 0.4 1.1 2.3 3.5 1.0 1.6 0.1 1.9 1.6 1.0 0.1 0.9 3.2 2.3 0.4 0.2 0.9 1.5 0.8 0.3 2.3 2.1 0.3 0.9 0.6 1.4 6.7 1.4 0.2 3.8 0.6 5.8 2.7 2.5 3.1 0.8 3.5 4.4 3.9 0.0 2.5 0.1 3.8 0.2 1.2 2.9 2.6 3.7 3.2 2.8 2.5 2.8 2.5 2.8 2.3 2.6 2.9 1.3 6.4 2.0 3.6 2.3 0.4 0.8 0.6 1.2 0.8 1.3 2.4 4.5 0.0 2.4 0.0 2.1 1.2 2.2 0.1 7.9 1.7 29.7 1.2 1.5 0.4 0.0 0.8 5.5 1.1 1.0 1.2 1.1 1.0 0.0 2.8 0.4 1.4 0.7 5.0 7.0 0.9 0.0 0.0 0.6 4.0 1.2 0.4 0.0 1.0 0.0 1.8 0.0 3.5 2.5 0.6 2.9 2.2 0.7 0.4 4.5 6.1 0.4 2.9 0.0 1.1 1.5 6.3 0.9 1.5 1.4 0.8 1.3 6.3 0.9 0.1 SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 47.8;salivary gland: 51.1;skeletal muscle: 119.4;tongue: 46.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.7;Basal respiratory cells: 30.8;Club cells: 33.9;Ionocytes: 30.5;Prostatic glandular cells: 27.4;Respiratory ciliated cells: 67.1;Skeletal myocytes: 77.3;Spermatogonia: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 36.3;LHCN-M2: 142.2;RH-30: 71.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Nucleoli "CAB058690: AB_2665581, HPA001893: AB_1079991" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (5.09e-2)" "prognostic unfavorable (8.92e-6)" "unprognostic (1.33e-2)" "unprognostic (1.44e-2)" "unprognostic (2.04e-3)" "prognostic favorable (3.94e-4)" "unprognostic (1.40e-1)" "unprognostic (9.15e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (3.06e-8)" "unprognostic (8.61e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" 5.5 0.4 0.3 0.0 0.5 0.0 1.9 0.5 1.2 15.2 1.0 0.0 0.0 0.0 0.4 1.1 0.8 0.5 0.0 0.3 0.3 0.0 0.0 1.5 0.5 0.3 0.4 0.2 0.3 47.8 19.8 0.0 0.4 13.2 0.0 0.0 51.1 0.2 119.4 0.3 0.0 0.0 0.3 0.0 0.4 1.7 0.5 9.7 1.9 46.3 0.2 1.6 0.8 0.4 15.2 3.5 0.6 28.1 17.0 20.6 0.4 4.1 10.6 4.9 4.0 0.0 8.2 0.0 2.2 0.6 2.1 4.4 10.3 6.4 2.1 0.0 17.1 2.0 1.9 6.8 0.0 0.0 0.2 15.6 4.9 2.3 0.7 36.3 0.3 1.6 5.8 0.0 142.2 2.8 0.0 0.5 0.0 0.0 8.9 0.0 71.9 0.0 5.9 16.3 2.5 0.3 5.0 0.3 6.1 0.5 3.3 0.4 13.9 6.7 5.4 7.9 6.5 0.5 0.1 0.0 1.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.2 0.3 0.3 0.3 0.4 0.4 0.3 0.5 0.4 0.8 3.2 1.5 0.0 0.0 0.1 30.7 30.8 0.6 0.0 1.0 0.8 0.9 0.0 33.9 1.8 0.0 0.2 0.0 0.1 1.9 0.0 0.2 1.1 0.1 1.6 0.0 0.0 0.0 0.8 0.4 5.7 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.5 0.0 0.0 0.6 0.0 0.3 0.0 1.9 0.0 0.8 0.0 1.0 0.1 0.2 0.0 1.2 0.0 27.4 0.0 0.1 67.1 0.2 0.0 77.3 5.1 0.0 25.0 0.1 0.1 0.3 0.1 0.1 0.0 18.3 SKP2 "FBL1, FBXL1, p45" ENSG00000145604 "S-phase kinase associated protein 2" Q13309 5 36151989-36196849 "Cancer-related genes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 37.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.4;Extravillous trophoblasts: 227.3;Syncytiotrophoblasts: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 274.7;RH-30: 286.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013491, CAB013533, HPA051196, HPA054633" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "CAB013491: AB_2533074, CAB013533: , HPA051196: AB_2681383, HPA054633: AB_2682550" "unprognostic (2.32e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" "unprognostic (5.74e-2)" "unprognostic (9.56e-2)" "unprognostic (1.52e-2)" "unprognostic (1.21e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.72e-7)" "prognostic favorable (8.57e-4)" "unprognostic (5.06e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (4.77e-15)" "unprognostic (2.50e-2)" "unprognostic (3.73e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-1)" 4.9 4.0 3.6 5.8 3.9 11.4 4.9 4.7 4.5 5.9 3.9 6.1 6.3 4.7 4.3 8.3 5.1 2.9 2.5 3.9 3.1 2.3 9.8 4.2 7.9 3.7 3.5 5.2 3.8 2.5 4.0 37.9 3.9 4.0 6.1 4.6 4.0 3.7 2.2 5.7 6.5 4.1 3.9 5.9 4.0 2.6 3.7 12.3 3.1 1.6 8.3 4.7 5.6 5.4 25.4 14.8 35.6 54.3 15.5 20.1 274.7 31.2 25.7 89.5 48.7 83.3 22.8 43.3 10.6 20.0 13.3 28.3 53.3 46.7 71.0 19.2 46.7 23.9 51.4 47.1 6.1 44.8 11.4 18.1 12.2 16.9 8.5 7.7 24.2 40.2 37.9 9.1 31.9 16.4 58.9 26.8 51.5 23.8 24.2 53.7 286.7 28.3 7.2 28.1 45.5 46.8 94.3 27.4 14.1 32.2 22.7 33.3 8.0 31.4 36.1 13.5 24.5 12.4 13.1 50.8 15.2 61.3 21.9 9.2 6.6 13.4 4.2 6.1 6.9 5.2 4.7 4.5 14.0 6.0 6.4 4.6 1.1 6.2 3.2 3.5 4.8 4.7 3.6 3.9 4.7 4.5 3.9 3.1 3.7 3.5 3.9 3.9 3.7 5.4 4.4 22.4 8.9 11.8 8.7 3.7 2.4 7.1 12.0 8.2 3.6 4.2 1.3 1.5 1.7 1.8 10.4 134.4 7.4 2.4 1.9 2.4 0.7 5.2 6.5 6.5 3.0 14.1 22.4 2.9 227.3 11.6 7.1 2.4 2.5 20.9 1.8 11.9 35.0 0.0 13.1 6.0 4.1 9.3 3.1 0.3 4.1 5.3 1.8 12.2 7.6 2.5 9.2 11.6 29.5 2.6 3.4 6.4 10.9 1.0 3.2 1.4 6.2 6.8 0.0 11.5 4.1 1.4 6.4 19.8 4.0 83.9 5.6 11.8 9.6 1.2 SLC19A1 "FOLT, RFC1" ENSG00000173638 "Solute carrier family 19 member 1" P41440 21 45493572-45573365 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 82.6" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 158.0;Syncytiotrophoblasts: 362.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 102.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 102.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024802 Approved Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA024802: AB_10602892" "unprognostic (4.31e-3)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.23e-2)" "unprognostic (2.02e-1)" "unprognostic (3.11e-1)" "unprognostic (3.04e-2)" "unprognostic (7.34e-2)" "unprognostic (2.87e-3)" "unprognostic (4.04e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.07e-10)" "unprognostic (1.44e-1)" "unprognostic (2.31e-1)" "unprognostic (7.97e-5)" "unprognostic (3.10e-1)" 7.7 9.4 8.2 5.7 4.0 8.1 5.9 5.6 12.4 10.0 82.6 6.8 22.5 6.4 0.9 3.2 6.9 1.9 4.2 11.8 2.7 8.0 20.9 15.7 4.2 5.3 5.2 11.8 6.9 0.8 5.4 13.6 6.0 5.8 0.8 2.3 3.3 0.8 2.6 3.9 7.9 1.1 3.0 15.1 7.4 4.6 6.6 2.2 13.8 0.5 0.7 4.3 5.2 4.1 28.9 23.7 4.9 19.4 1.5 2.1 40.2 12.5 1.9 11.1 7.0 55.1 26.1 26.8 24.9 2.8 9.1 14.1 9.0 8.5 2.7 25.2 51.2 54.7 12.4 38.8 6.1 37.2 8.5 2.7 6.3 11.6 3.3 3.3 9.1 27.3 67.6 11.8 3.5 29.3 49.6 29.9 28.5 11.2 30.0 66.5 5.4 79.2 4.6 16.9 29.7 26.7 14.9 23.5 11.2 6.7 18.4 41.4 10.7 14.6 18.8 4.3 21.1 4.8 18.5 23.5 6.7 56.4 11.9 1.6 18.5 24.1 0.9 16.3 2.8 2.5 1.4 2.0 13.4 0.8 2.0 1.5 102.9 1.1 10.8 4.1 3.2 7.9 8.2 4.0 5.6 12.4 11.8 2.7 5.3 5.2 6.0 3.0 6.6 4.1 1.4 48.1 6.3 13.7 2.9 2.4 2.0 2.6 1.8 23.6 3.9 3.4 2.5 1.5 6.2 0.0 0.0 158.0 0.5 8.2 0.0 8.0 3.7 2.2 5.8 3.4 0.0 6.7 3.4 4.9 21.5 3.7 4.1 4.5 1.3 12.7 1.1 16.2 27.3 8.4 4.0 4.1 8.2 11.1 5.0 6.6 6.5 8.6 3.6 23.4 8.3 5.7 0.0 2.0 1.7 7.6 5.4 11.3 9.4 4.6 20.5 2.4 0.9 3.6 0.0 3.3 4.1 1.5 4.8 1.8 1.6 362.4 2.6 5.1 8.5 0.9 SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1735.2;Microglial cells: 332.6;Muller glia cells: 472.6;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 249.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 50.0;CACO-2: 112.6;HaCaT: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" 30.7 16.4 500.4 7.4 544.2 3.3 17.7 549.4 776.8 8.7 400.6 3.0 0.5 1.6 1.1 10.5 6.0 8.0 45.4 514.6 502.5 2.2 3.8 10.2 17.4 477.6 510.1 12.6 5.0 2.2 18.1 20.3 502.4 3.2 1.1 221.1 4.7 4.7 14.1 6.0 3.2 4.1 495.4 9.3 2.2 1.2 532.8 3.6 3.4 9.2 5.4 7.0 5.3 494.9 1.3 0.2 50.0 5.3 5.9 14.3 37.7 0.3 0.0 2.4 4.9 112.6 5.6 0.0 27.8 2.3 1.0 71.4 16.9 9.1 2.2 1.8 33.0 0.0 0.5 0.0 2.5 1.3 0.6 26.9 34.5 14.4 5.3 1.8 0.0 1.1 0.0 0.2 8.7 0.2 0.1 0.1 6.0 0.1 5.9 0.0 0.5 0.0 0.1 3.1 4.7 0.0 5.1 14.6 2.1 24.4 0.2 3.1 0.0 6.2 10.3 0.1 20.7 0.0 0.0 0.3 21.7 37.7 12.6 0.0 1.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 500.4 544.2 549.4 776.8 514.6 502.5 477.6 510.1 502.4 495.4 532.8 494.9 1.1 3.2 0.5 1735.2 0.7 10.7 14.3 19.0 83.1 7.1 3.7 3.4 36.0 0.0 3.1 0.0 2.1 32.9 0.1 0.0 0.0 0.8 0.7 16.3 1.2 8.9 0.0 0.8 2.6 0.0 15.9 7.8 2.0 11.7 0.0 0.2 1.1 0.5 41.2 3.3 4.7 0.0 0.0 77.6 5.9 4.1 4.4 59.6 7.2 332.6 3.3 472.6 0.0 237.7 249.0 0.3 0.0 0.0 0.7 5.2 0.0 0.0 5.3 19.1 6.6 2.6 3.1 0.3 0.3 32.7 7.1 9.2 1.0 20.7 0.0 3.6 SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1120.4" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 2328.4" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036055 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" 1.1 0.0 0.0 19.7 0.0 0.0 59.5 0.2 0.1 0.3 0.0 1120.4 576.9 0.9 15.3 0.5 0.8 17.8 0.0 0.0 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.1 878.8 0.1 0.0 129.9 0.0 0.1 118.5 15.0 0.0 0.0 1.3 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 165.9 4.2 0.0 0.3 0.0 0.0 0.0 51.4 41.7 0.3 34.3 0.0 0.0 0.0 0.0 0.0 2328.4 0.0 0.0 6.4 1.8 0.1 0.3 14.3 0.0 110.2 0.0 0.0 0.1 0.0 0.2 26.7 0.2 0.0 0.1 0.0 0.0 114.3 32.5 0.0 0.0 0.0 0.6 0.3 0.1 0.0 89.9 0.0 0.0 0.0 101.6 182.1 0.0 503.4 0.0 0.0 0.3 388.9 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 0.0 86.0 0.1 SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 98.7;skin 1: 79.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 833.8;Erythroid cells: 520.4;Extravillous trophoblasts: 536.4;Syncytiotrophoblasts: 2482.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 241.0;CACO-2: 219.9;Hep G2: 157.4" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" No No 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "CAB002759: , HPA031345: AB_2673835, HPA058494: AB_2683734" "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavorable (3.65e-8)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.05e-4)" 6.9 3.6 24.1 2.5 26.1 41.6 7.8 33.7 27.7 28.6 43.6 6.1 0.4 5.1 1.4 54.1 8.2 1.7 10.0 20.6 28.5 14.2 1.7 3.3 1.0 31.9 29.3 5.5 2.1 4.5 4.8 98.7 34.5 6.0 1.0 24.6 17.6 5.1 2.0 79.8 4.6 0.4 24.7 7.5 8.4 2.1 41.2 1.0 3.0 1.5 2.1 19.3 54.2 29.4 60.5 52.9 66.3 6.2 3.5 1.2 241.0 47.8 36.9 15.5 27.8 219.9 96.3 22.2 138.9 6.0 26.5 43.6 12.5 52.3 14.8 16.4 10.3 29.8 20.9 157.4 12.9 16.8 8.1 3.3 21.3 18.3 20.5 96.7 2.9 12.8 81.2 1.5 11.7 46.6 7.4 11.7 35.1 22.1 17.9 8.4 20.6 23.3 21.7 17.9 27.0 23.8 47.7 95.6 11.0 70.0 3.8 16.9 14.9 25.6 28.6 6.1 83.8 5.3 6.5 11.5 57.1 8.2 25.5 0.5 0.1 1.2 10.6 0.3 8.5 10.9 5.1 6.7 3.7 8.3 3.8 4.8 0.2 4.3 0.1 18.4 6.2 4.0 24.1 26.1 33.7 27.7 20.6 28.5 31.9 29.3 34.5 24.7 41.2 29.4 3.1 0.0 1.8 12.7 25.4 286.1 48.8 286.3 66.0 15.8 41.4 21.8 26.7 20.0 159.3 27.6 66.7 833.8 33.5 53.1 5.9 53.2 4.0 112.1 46.0 100.5 18.4 520.4 2.8 11.7 536.4 25.9 11.7 118.9 6.3 6.8 2.2 2.1 84.8 5.0 3.2 22.4 65.1 1.6 34.2 0.3 7.8 5.0 21.4 71.2 36.0 350.1 18.6 8.0 9.9 120.3 51.9 14.7 11.6 31.2 1.9 2.2 118.1 32.1 0.0 9.8 32.1 0.1 2.4 99.1 238.3 2482.5 20.8 5.5 11.8 105.8 SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 477.5;Alveolar cells type 2: 1315.9;Club cells: 179.9;Glandular and luminal cells: 241.3;Respiratory ciliated cells: 217.0" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 82 "BEWO: 32.2;EFO-21: 121.0;RPTEC TERT1: 86.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" 0.4 0.8 0.0 0.3 0.0 0.0 19.1 2.1 0.2 66.6 6.9 0.1 16.4 34.6 0.1 1.5 69.8 9.0 0.2 0.1 0.0 16.7 1.2 753.0 0.1 0.0 0.0 1.3 7.3 0.0 2.1 4.8 0.1 1.0 0.0 0.5 90.2 16.8 0.1 2.6 4.3 0.2 0.0 0.7 2.5 2.7 0.3 2.1 33.6 0.0 7.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 32.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 121.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.1 0.0 0.2 0.1 0.1 86.8 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 477.5 1315.9 0.0 0.1 0.0 0.1 79.1 0.0 0.0 41.5 7.5 0.8 34.3 179.9 20.2 0.0 1.4 0.0 0.0 5.9 72.2 5.4 78.6 30.3 2.5 0.0 0.0 0.1 8.5 0.0 2.6 0.0 241.3 29.0 0.0 0.0 0.0 0.2 0.0 0.1 1.2 26.4 0.0 0.0 20.8 1.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 2.5 0.0 0.0 11.8 13.6 3.4 217.0 0.0 0.0 0.0 5.8 2.1 0.1 0.0 0.0 0.3 4.8 0.0 1.8 4.0 SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 780.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 1441.0;SiHa: 1287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" 103.3 105.6 130.5 46.7 138.0 122.0 108.9 140.1 160.4 101.6 115.6 60.6 51.5 97.2 65.3 112.9 94.0 35.8 52.0 123.1 133.3 171.2 71.9 117.8 34.9 138.4 132.6 93.0 109.7 189.7 65.3 55.4 134.0 100.8 23.1 22.8 110.6 41.9 122.3 127.1 79.7 33.8 135.8 77.4 90.2 65.1 154.5 30.1 110.2 26.0 28.8 77.7 95.1 130.6 155.5 675.7 60.2 213.2 89.7 69.7 596.7 267.5 106.2 154.0 126.3 643.3 293.0 173.9 290.5 185.4 284.5 540.0 123.1 588.9 84.3 319.3 114.0 117.5 422.4 299.2 825.7 136.0 169.4 144.9 1441.0 175.3 528.8 46.2 83.6 380.7 232.9 347.4 95.1 792.6 149.8 181.3 106.9 222.5 214.2 153.8 92.7 341.8 113.9 84.0 112.5 53.5 1287.0 499.6 948.5 121.2 161.5 182.6 146.2 138.3 200.0 204.4 195.5 436.0 556.1 561.2 135.0 225.1 418.0 37.8 149.0 49.7 117.9 147.4 157.7 58.3 107.3 122.1 88.6 72.1 90.1 97.2 31.2 90.3 123.9 304.7 112.5 186.3 130.5 138.0 140.1 160.4 123.1 133.3 138.4 132.6 134.0 135.8 154.5 130.6 97.8 48.1 37.3 91.1 78.8 218.1 244.2 321.7 399.5 58.4 124.2 120.8 13.4 30.0 141.1 49.7 66.7 222.5 136.2 109.6 33.2 161.9 31.5 122.0 96.3 149.2 84.3 117.7 16.9 151.1 143.7 102.9 71.4 179.7 84.3 43.2 99.2 27.0 202.9 53.8 25.1 60.4 223.8 54.1 140.9 28.9 30.4 141.5 224.1 29.0 104.7 188.4 40.2 21.1 11.3 130.6 58.7 30.5 140.9 156.9 120.7 227.4 63.4 61.2 6.6 71.8 114.6 21.3 31.9 160.7 150.6 780.7 118.1 52.4 60.7 194.9 SLC44A3 "CTL3, MGC45474" ENSG00000143036 "Solute carrier family 44 member 3" Q8N4M1 1 94820342-94895246 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.8" "Lineage enriched" "Detected in single" 18 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "OE19: 35.9;RPTEC TERT1: 101.4;RT4: 69.5" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in all" HPA047433 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047433: AB_2680046" "unprognostic (8.06e-2)" "unprognostic (7.65e-2)" "unprognostic (4.63e-3)" "unprognostic (3.57e-2)" "unprognostic (1.53e-2)" "unprognostic (2.37e-1)" "unprognostic (1.14e-1)" "unprognostic (4.03e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-1)" "unprognostic (5.78e-2)" "unprognostic (2.44e-2)" "prognostic favorable (7.63e-5)" "unprognostic (9.09e-2)" "unprognostic (8.28e-2)" "unprognostic (5.95e-2)" "unprognostic (3.31e-3)" 2.2 8.8 15.7 6.2 15.3 0.1 8.1 17.9 16.9 8.8 14.0 31.5 26.1 7.2 6.6 9.4 8.0 10.9 3.9 14.8 17.0 29.3 6.3 10.3 0.8 20.7 16.4 1.7 27.0 5.2 15.0 3.4 16.4 10.8 35.4 4.3 23.4 7.7 0.2 6.0 28.0 2.8 17.6 0.9 29.3 2.5 15.7 4.9 5.2 0.6 2.2 22.1 6.5 18.3 23.4 3.2 0.8 0.0 2.5 3.2 15.9 0.4 3.4 0.8 3.7 21.4 5.8 0.0 15.4 0.4 6.9 7.7 3.5 5.5 1.4 0.0 4.1 0.0 1.2 1.7 1.1 0.0 0.0 9.9 5.1 1.6 0.0 6.3 0.4 0.0 0.0 0.0 1.4 3.4 0.0 0.3 1.0 35.9 0.8 1.8 0.7 1.3 101.4 69.5 10.4 17.0 1.0 10.8 7.8 7.3 6.2 0.7 0.0 0.5 3.5 1.5 0.2 0.0 0.0 0.0 2.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 15.3 17.9 16.9 14.8 17.0 20.7 16.4 16.4 17.6 15.7 18.3 0.4 25.6 6.7 26.1 0.6 3.1 27.8 14.6 4.0 0.7 15.6 8.3 5.7 37.1 22.7 12.9 0.0 15.9 0.1 18.2 15.6 33.4 32.5 12.8 3.2 1.3 16.3 0.0 1.4 27.8 0.8 3.8 16.3 22.5 1.3 5.3 0.7 2.1 1.3 0.0 4.6 32.2 20.3 0.3 0.4 5.3 5.0 0.8 5.4 2.8 1.0 17.0 0.0 5.5 2.0 38.3 36.5 10.9 0.0 12.9 22.8 38.6 11.4 0.2 0.0 9.6 3.4 0.1 0.2 10.2 3.8 6.7 0.8 4.1 42.8 30.3 SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "prostate: 306.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 19.9;granulocytes: 119.2;Oligodendrocytes: 47.1;Prostatic glandular cells: 67.2" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.5" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.5" "Cell line enriched" "Detected in many" 29 "HMC-1: 834.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" 1.4 3.6 6.7 3.2 19.5 0.8 1.6 17.6 13.4 3.7 1.9 4.8 4.6 1.7 0.5 1.6 2.1 3.8 1.5 8.0 10.3 2.1 11.2 3.4 2.7 25.1 17.3 2.7 0.8 0.3 4.7 0.5 21.8 306.4 3.2 0.1 2.8 0.6 5.6 1.5 4.8 1.0 12.6 12.4 16.8 1.4 16.6 0.5 1.0 2.3 0.8 2.8 1.1 44.7 9.7 3.0 2.8 2.7 0.0 0.1 2.2 1.3 0.3 3.3 2.7 7.1 18.0 2.7 4.6 0.3 3.0 3.5 1.6 3.3 0.5 3.9 2.9 29.0 0.6 2.0 1.9 5.0 834.2 0.3 1.1 2.3 0.0 2.2 9.4 4.5 4.9 1.7 1.4 2.3 0.8 8.5 12.2 16.7 10.7 1.0 4.1 1.5 3.7 13.7 1.2 2.9 1.5 20.6 3.9 2.3 4.7 1.4 9.6 1.4 9.5 3.5 7.1 0.4 0.6 0.4 1.8 1.5 7.1 40.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 19.5 17.6 13.4 8.0 10.3 25.1 17.3 21.8 12.6 16.6 44.7 0.2 0.0 3.2 1.0 4.0 0.0 1.0 0.6 0.0 0.4 1.5 1.8 2.0 2.8 1.0 1.8 0.0 0.5 0.1 5.7 0.0 1.7 0.2 1.9 0.2 1.7 0.0 3.4 0.2 0.5 0.1 0.7 19.9 0.2 119.2 0.2 0.7 6.6 1.9 0.0 0.3 6.9 2.0 1.0 0.3 0.4 1.8 2.0 0.0 0.0 0.6 0.1 0.0 2.0 47.1 3.9 8.0 1.5 0.3 67.2 0.9 1.8 3.2 0.1 6.6 0.1 0.8 0.0 2.6 0.4 0.1 0.0 0.9 0.2 6.7 0.9 SLC4A5 NBC4 ENSG00000188687 "Solute carrier family 4 member 5" Q9BY07 2 74216242-74343414 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Sodium transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 73.4;retina: 42.0;thyroid gland: 26.7" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 168.2" "Cancer enriched" "Detected in single" 11 "thyroid cancer: 3.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 4.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "U-266/70: 8.8" "Group enriched" "Detected in many" 5 "basal ganglia: 1.6;hippocampal formation: 5.2;pons and medulla: 6.5;thalamus: 3.5" "Low region specificity" "Detected in many" HPA036621 Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA036621: AB_10696779" "unprognostic (1.30e-1)" "unprognostic (3.78e-2)" "unprognostic (2.75e-2)" "unprognostic (1.83e-4)" "unprognostic (3.38e-1)" "unprognostic (2.36e-2)" "unprognostic (2.56e-3)" "unprognostic (5.37e-4)" "unprognostic (1.39e-1)" "unprognostic (2.55e-1)" "unprognostic (1.55e-3)" "unprognostic (3.24e-2)" "unprognostic (1.72e-5)" "unprognostic (1.57e-1)" "unprognostic (1.06e-2)" "unprognostic (8.47e-2)" "unprognostic (9.27e-4)" 1.6 0.7 3.3 1.1 5.2 2.3 1.4 12.5 4.6 1.3 73.4 1.2 0.7 1.4 2.3 0.9 2.1 1.0 1.4 6.1 4.1 1.0 1.0 2.6 1.8 5.3 4.8 1.6 1.5 12.4 2.4 0.6 4.8 1.2 0.7 42.0 1.7 1.3 1.8 5.0 1.0 1.5 2.8 1.3 0.9 16.1 5.3 1.0 26.7 1.5 0.8 1.1 1.1 8.5 0.3 0.5 0.9 0.9 0.9 1.6 0.9 0.2 0.9 0.5 0.7 0.3 0.7 1.5 0.2 0.0 0.3 0.1 1.0 0.1 0.2 1.2 0.6 2.2 0.7 0.5 0.1 0.5 1.3 0.4 1.3 0.0 0.2 0.5 0.3 1.0 0.5 1.5 0.2 3.5 0.3 1.5 0.4 0.5 0.3 0.8 0.7 0.0 0.2 0.6 0.6 1.2 0.3 1.1 1.6 0.7 0.8 1.5 0.0 0.9 1.6 0.9 0.3 8.8 1.4 1.0 0.6 0.8 0.2 4.3 0.3 0.3 0.6 0.3 0.4 0.7 1.0 0.9 0.3 0.9 0.8 1.0 1.9 0.7 0.1 2.5 1.2 0.2 3.3 5.2 12.5 4.6 6.1 4.1 5.3 4.8 4.8 2.8 5.3 8.5 1.1 3.2 10.8 16.0 0.5 0.6 0.6 0.3 0.0 13.9 0.6 0.5 0.4 1.5 2.6 0.0 35.5 0.1 3.3 0.3 0.0 0.4 0.6 1.0 0.7 0.9 0.0 0.4 7.3 0.6 0.0 0.8 0.0 0.8 0.0 1.1 0.7 0.0 0.1 168.2 10.6 0.5 0.0 0.0 0.4 0.6 1.2 0.4 1.8 4.7 0.1 3.3 2.1 4.0 31.1 0.5 0.3 0.4 0.1 0.6 0.3 0.1 4.1 40.4 0.0 2.5 1.1 1.7 1.3 0.0 0.4 0.0 0.6 0.3 0.2 0.7 SLPI "ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4" ENSG00000124107 "Secretory leukocyte peptidase inhibitor" P03973 20 45252239-45254564 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 27919.2;salivary gland: 14140.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 4134.5;Basal respiratory cells: 18759.4;Club cells: 20435.8;Respiratory ciliated cells: 8096.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 79 "neutrophil: 321.8" "Lineage enriched" "Detected in many" 79 "granulocytes: 321.8" "Cell line enhanced" "Detected in many" "EFO-21: 1719.5;hTCEpi: 2037.1;OE19: 767.9;SiHa: 622.1;THP-1: 531.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002303, HPA027774" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 26400000 9600000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "CAB002303: AB_564008, HPA027774: AB_10602405" "unprognostic (2.31e-2)" "unprognostic (3.07e-1)" "unprognostic (3.10e-2)" "unprognostic (2.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.16e-2)" "unprognostic (9.98e-2)" "unprognostic (2.90e-1)" "unprognostic (3.23e-1)" "unprognostic (1.83e-3)" "unprognostic (4.01e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (6.91e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-1)" "unprognostic (8.81e-2)" "unprognostic (8.31e-2)" 259.4 13.8 4.1 70.8 4.3 353.5 306.7 5.0 22.5 27919.2 28.9 97.8 4.5 107.1 16.5 1372.7 714.2 294.7 68.4 4.5 4.8 382.6 268.0 1181.7 2.0 5.6 5.5 11.5 36.1 5.5 470.2 8.3 5.5 112.6 106.7 0.6 14140.1 2946.3 599.9 272.4 19.9 14.0 4.8 22.5 154.7 28.1 10.4 47.7 30.4 51.5 215.8 226.6 685.3 4.8 4.9 19.4 0.0 0.3 0.2 0.0 1.1 0.1 0.0 0.1 0.0 1.5 318.7 0.9 1719.5 0.2 23.9 132.8 0.0 64.1 0.0 8.6 0.3 0.3 227.1 0.2 326.4 0.5 1.0 8.8 2037.1 0.1 134.0 0.0 0.2 0.0 0.2 0.3 0.0 0.4 0.4 24.4 0.4 767.9 120.1 0.6 0.7 0.1 355.5 14.6 0.3 0.0 622.1 131.4 1.8 0.4 2.8 531.8 0.3 0.4 8.5 1.2 1.1 1.2 9.7 6.1 0.0 33.0 0.5 3.6 0.9 0.4 0.1 3.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 321.8 0.0 4.0 0.0 0.0 7.9 4.1 4.3 5.0 22.5 4.5 4.8 5.6 5.5 5.5 4.8 10.4 4.8 6.3 1807.7 4134.5 0.3 5.4 100.7 1330.7 18759.4 2.2 0.0 594.2 607.6 3.9 1609.9 20435.8 3428.2 0.0 2.3 10.1 225.8 0.0 407.5 381.6 632.0 170.7 43.3 200.2 18.7 0.0 258.9 1.2 326.0 193.7 1398.8 77.0 0.0 15.7 508.5 6.8 0.0 0.0 74.7 2616.3 8.5 73.3 69.8 25.4 27.1 39.2 0.0 5.3 0.0 0.0 1.0 0.1 901.6 370.3 0.0 1.3 1289.4 2.7 3.4 8096.4 0.0 0.0 8.6 971.2 1.8 1.8 347.3 138.9 2.1 29.5 0.0 224.5 3338.5 SMAD1 "JV4-1, MADH1, MADR1" ENSG00000170365 "SMAD family member 1" Q15797 4 145481194-145559176 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 195.9;Endothelial cells: 76.3;Late spermatids: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 46.2;non-classical monocyte: 22.2" "Group enriched" "Detected in many" 5 "granulocytes: 46.2;monocytes: 22.2" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005389 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB005389: AB_656608" "unprognostic (8.20e-2)" "unprognostic (1.63e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.74e-1)" "unprognostic (6.85e-2)" "unprognostic (1.70e-1)" "unprognostic (6.02e-2)" "unprognostic (2.30e-1)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (4.68e-2)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" "unprognostic (5.88e-2)" "unprognostic (1.14e-3)" "unprognostic (3.15e-2)" 19.6 5.3 16.7 10.9 21.9 5.8 15.9 15.3 18.2 20.4 6.9 20.4 15.4 29.0 32.7 16.3 24.4 17.1 13.1 13.2 16.6 12.6 20.2 12.3 17.6 14.6 18.3 11.7 13.3 29.1 6.0 11.4 14.5 12.5 20.8 6.5 12.9 17.2 20.7 24.4 15.7 30.4 13.6 14.0 10.6 13.9 16.4 18.3 17.4 17.8 13.7 17.9 8.9 13.6 9.6 12.6 23.5 27.3 8.7 12.8 11.5 13.9 32.6 22.0 16.4 6.2 34.0 9.8 8.0 31.8 9.7 14.1 26.6 30.2 12.8 0.0 13.5 0.0 10.0 13.1 23.2 15.8 2.4 17.6 35.2 11.8 22.9 17.9 110.7 20.7 11.1 0.4 27.0 9.6 24.4 0.3 21.8 15.3 14.6 47.0 21.1 28.5 25.9 17.1 35.3 17.6 18.8 40.3 9.6 14.1 14.0 0.2 32.4 10.5 14.5 11.3 8.6 31.1 0.0 56.1 16.7 0.3 11.1 46.2 3.6 1.5 0.0 9.4 0.0 0.0 0.6 0.0 6.8 0.1 0.3 0.0 0.0 2.4 22.2 0.0 1.3 1.3 16.7 21.9 15.3 18.2 13.2 16.6 14.6 18.3 14.5 13.6 16.4 13.6 62.9 9.6 10.9 54.9 0.1 11.5 17.5 22.0 45.5 6.6 8.6 9.3 3.6 12.8 16.3 14.7 14.6 5.2 0.8 13.2 7.9 12.6 195.9 19.5 12.1 76.3 9.1 8.4 47.7 18.5 2.7 11.5 12.2 24.8 0.0 10.0 10.4 12.0 2.5 10.1 43.2 10.4 28.5 6.5 2.7 80.7 4.4 4.5 1.8 26.2 3.2 5.3 0.0 66.9 22.0 12.0 10.2 5.7 0.3 17.5 6.6 11.5 12.7 5.9 0.0 19.0 10.6 8.3 16.8 19.9 12.6 2.2 1.2 6.9 8.8 17.2 SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli, Cytosol" "CAB025507: , CAB073546: , HPA067203: AB_2685803" "unprognostic (1.55e-1)" "unprognostic (2.49e-1)" "unprognostic (1.43e-2)" "unprognostic (9.82e-3)" "unprognostic (9.88e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.91e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-3)" "unprognostic (6.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.20e-3)" "unprognostic (2.68e-1)" "unprognostic (6.13e-2)" "unprognostic (3.20e-2)" "unprognostic (6.28e-2)" 48.6 52.6 38.0 38.6 42.4 37.5 46.5 46.2 36.7 43.2 35.6 47.5 36.7 38.6 41.0 55.0 46.8 39.6 53.8 32.9 48.6 43.3 35.6 46.7 44.5 50.2 43.2 52.5 40.4 44.6 20.3 42.7 51.9 36.4 48.7 70.5 36.7 44.8 57.4 34.0 37.4 47.9 47.8 47.5 45.2 51.5 42.4 72.4 75.7 55.5 55.2 53.8 31.1 59.4 81.1 113.7 68.0 66.2 106.1 128.5 77.4 86.1 102.7 87.9 101.8 43.8 75.6 124.8 60.3 110.0 123.0 86.6 77.2 96.1 116.9 136.4 39.3 106.4 164.4 71.9 123.2 149.6 104.1 95.8 121.4 75.5 172.9 102.1 98.6 99.7 50.3 101.6 109.6 52.7 103.4 71.6 33.6 4.4 26.7 74.4 98.9 85.9 197.8 137.2 62.8 73.3 103.7 70.1 85.7 65.8 53.5 97.7 111.4 129.5 74.2 35.6 63.6 99.0 102.7 108.3 89.6 99.9 97.1 58.8 33.6 38.7 23.8 38.5 29.8 16.7 32.3 29.9 32.8 13.9 35.3 27.6 34.1 38.6 33.0 23.3 40.5 31.6 38.0 42.4 46.2 36.7 32.9 48.6 50.2 43.2 51.9 47.8 42.4 59.4 55.0 44.8 36.1 55.8 36.3 54.4 44.1 38.3 54.1 48.0 44.2 30.2 49.2 41.5 45.5 77.3 212.7 48.2 53.0 42.8 39.2 36.5 68.1 58.6 53.0 53.1 51.0 36.4 63.4 43.5 40.3 40.5 44.4 68.1 21.5 80.0 56.4 29.6 43.9 35.3 50.5 46.1 38.7 57.3 41.8 131.9 41.7 48.7 51.6 104.9 63.9 44.8 72.1 96.0 130.0 44.0 31.6 53.4 34.5 66.1 37.9 39.5 41.8 88.1 32.9 53.5 39.6 37.2 39.4 59.2 61.8 69.5 47.4 41.7 42.3 77.2 SMAD3 "HsT17436, JV15-2, MADH3" ENSG00000166949 "SMAD family member 3" P84022 15 67063763-67195173 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 162.5;Prostatic glandular cells: 149.3;Urothelial cells: 276.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008094, HPA046386, HPA067203, CAB069409" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB008094: AB_2302271, CAB069409: AB_1622941, HPA046386: AB_2679647, HPA067203: AB_2685803" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (1.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-2)" "unprognostic (8.40e-3)" "unprognostic (1.80e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (2.93e-1)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (5.97e-2)" 30.0 6.3 17.9 15.8 22.4 18.8 22.2 6.8 16.1 32.2 31.5 15.4 17.7 20.3 13.6 51.9 23.3 21.2 28.1 16.1 9.3 35.7 19.8 21.4 16.8 17.0 9.0 30.7 18.2 10.5 14.5 16.8 9.3 24.4 12.9 6.2 17.2 13.8 55.0 29.1 21.6 21.1 10.9 15.4 22.2 3.9 12.9 19.6 30.2 39.0 25.7 43.6 31.5 8.5 49.3 157.0 30.6 13.9 50.8 115.9 22.5 27.6 114.0 37.8 30.7 33.7 125.3 16.5 36.6 79.4 169.8 111.3 31.2 116.9 38.1 13.1 11.9 1.8 43.4 26.2 38.2 6.6 2.7 106.5 26.7 33.2 27.7 83.2 128.2 5.2 40.3 40.8 47.1 24.2 1.5 26.0 17.7 26.1 50.5 1.6 9.1 5.9 25.2 149.4 0.8 10.3 36.6 19.5 32.5 59.2 5.3 30.2 109.4 50.4 47.1 36.5 31.7 16.5 5.0 21.0 45.8 7.0 45.9 0.0 1.0 2.3 3.2 0.9 3.3 1.2 3.6 3.4 1.0 2.8 1.6 1.4 0.0 0.3 0.9 1.5 1.9 1.1 17.9 22.4 6.8 16.1 16.1 9.3 17.0 9.0 9.3 10.9 12.9 8.5 18.2 48.1 19.9 28.4 33.9 89.0 90.2 70.6 53.5 10.8 13.3 10.5 12.2 17.2 49.6 36.8 6.2 1.1 19.7 48.2 3.9 61.9 1.0 23.6 30.2 26.6 3.5 9.1 63.2 50.7 4.2 42.6 28.5 75.2 24.1 162.5 11.4 12.6 10.7 0.0 6.9 13.0 24.4 6.2 40.8 5.7 26.8 18.8 21.4 67.5 9.7 8.5 20.6 140.2 1.3 99.7 49.2 20.7 10.6 149.3 34.2 14.0 52.2 0.6 26.3 28.9 27.5 0.6 2.3 70.3 48.9 1.6 21.6 18.8 16.6 276.2 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favorable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 16.4 11.8 9.0 10.9 10.3 10.6 17.2 21.7 10.5 18.5 11.2 14.9 11.9 20.6 9.8 15.7 16.3 12.8 14.1 11.7 10.0 16.1 19.1 13.1 12.7 9.0 8.2 24.0 21.4 19.9 11.3 18.9 9.4 21.8 14.3 18.3 14.0 18.0 24.9 14.6 12.1 18.9 8.0 13.9 15.2 14.2 11.9 17.7 21.4 24.9 14.5 13.5 13.1 13.8 16.4 22.5 59.4 16.6 23.9 36.6 31.4 27.7 32.2 39.4 49.6 13.0 3.8 25.9 7.8 25.6 19.6 24.9 33.6 13.2 40.7 19.3 14.8 20.6 20.5 15.9 23.7 34.8 13.1 16.6 21.9 19.1 27.8 37.0 28.7 14.0 21.9 25.8 23.5 9.0 18.8 10.0 31.2 9.1 14.3 23.3 30.6 26.9 18.2 7.4 34.4 20.3 27.0 5.0 18.8 24.8 13.3 19.4 20.0 34.5 13.3 8.8 19.7 30.6 28.6 26.2 21.2 12.8 22.6 0.3 0.6 0.6 1.0 0.4 1.1 0.7 1.0 0.8 1.2 0.9 1.2 1.5 1.0 1.0 0.4 1.0 1.4 0.5 9.0 10.3 21.7 10.5 11.7 10.0 9.0 8.2 9.4 8.0 11.9 13.8 32.5 22.4 29.1 55.2 21.0 25.6 20.9 15.1 18.8 17.1 27.3 20.4 38.8 24.3 19.3 22.0 20.9 20.7 24.0 22.7 11.7 16.9 10.6 30.4 36.6 26.2 39.6 12.4 37.0 12.5 20.6 30.3 28.5 35.2 4.5 132.4 28.5 44.1 15.1 15.2 39.0 32.1 16.2 28.5 20.9 16.2 33.2 21.1 28.4 49.6 16.9 20.4 17.5 41.2 72.5 20.1 21.0 30.5 24.8 36.3 26.7 22.6 22.4 20.0 26.3 32.2 34.2 17.2 18.8 20.9 27.3 12.6 20.1 22.1 24.5 29.7 SMARCA4 "BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2" ENSG00000127616 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" P51532 19 10960932-11079426 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase, Repressor, RNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 372.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004208, HPA048340" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Nucleoli fibrillar center, Nucleoli rim" "CAB004208: AB_626762, HPA048340: " "unprognostic (2.68e-1)" "unprognostic (4.85e-2)" "unprognostic (1.71e-1)" "unprognostic (3.43e-3)" "unprognostic (1.40e-1)" "unprognostic (6.33e-3)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.19e-2)" "unprognostic (7.29e-2)" "unprognostic (1.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-2)" "unprognostic (6.80e-3)" "unprognostic (6.83e-3)" "unprognostic (5.44e-2)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 13.8 16.2 14.4 22.6 14.3 31.8 13.0 15.3 23.7 16.1 13.2 18.1 19.9 14.5 9.5 32.9 20.8 13.3 16.2 15.4 9.6 15.7 8.6 17.9 27.0 10.4 10.4 14.9 18.3 22.9 11.1 20.2 11.0 17.7 12.9 19.7 25.9 15.6 23.7 28.1 17.2 14.5 3.9 19.5 20.4 30.2 11.8 43.1 20.6 13.9 23.7 17.4 14.7 19.3 92.5 5.0 157.2 149.8 30.3 25.4 68.9 62.7 37.2 74.6 54.9 126.9 4.0 215.4 94.2 54.9 3.0 65.9 123.6 77.5 40.8 89.5 93.3 171.3 76.5 149.6 45.7 125.5 82.0 43.1 36.7 63.1 64.5 33.3 67.5 92.0 156.7 78.3 59.2 188.0 210.0 107.5 159.9 45.1 134.7 220.6 99.5 111.7 47.9 114.8 177.8 161.7 66.6 84.4 73.5 50.1 71.9 93.3 90.9 110.3 57.3 102.5 104.9 160.6 192.2 209.1 62.6 118.5 96.0 5.7 5.8 6.4 9.3 6.9 8.2 5.3 6.8 7.9 6.1 6.8 7.6 7.5 3.4 8.5 10.8 7.9 6.4 4.7 14.4 14.3 15.3 23.7 15.4 9.6 10.4 10.4 11.0 3.9 11.8 19.3 25.4 67.3 72.6 27.4 28.5 37.0 43.7 43.8 24.5 91.3 42.2 28.4 372.9 40.0 62.7 44.1 70.9 65.9 21.2 60.1 41.1 79.8 53.0 58.8 49.2 58.3 63.2 41.8 32.2 61.4 57.3 43.8 50.0 63.5 30.4 75.3 28.5 21.9 42.3 101.0 39.6 47.7 57.0 23.8 21.5 37.6 26.1 30.4 16.0 14.0 43.8 36.1 23.7 32.6 28.1 76.4 41.8 13.5 37.6 66.0 29.8 27.6 62.5 69.1 13.1 45.1 66.4 99.4 86.0 52.2 51.7 61.0 30.4 68.1 60.5 50.1 SMARCB1 "BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838009 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165" "unprognostic (2.15e-1)" "unprognostic (5.62e-2)" "unprognostic (6.60e-3)" "unprognostic (1.63e-2)" "unprognostic (4.01e-3)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.52e-4)" "unprognostic (4.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.10e-2)" "unprognostic (4.43e-3)" "prognostic favorable (1.14e-6)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (7.04e-2)" 35.9 46.4 2.3 6.9 2.5 3.3 40.3 4.1 10.0 51.5 2.7 40.9 8.1 51.4 0.4 51.0 40.4 2.2 44.0 2.3 2.3 47.0 36.9 32.3 5.8 4.3 2.7 63.1 43.9 1.2 48.0 1.2 2.7 36.6 1.1 25.3 44.1 0.6 48.1 50.1 51.7 0.6 2.2 51.7 40.4 68.3 2.3 3.5 41.3 1.8 1.5 37.5 40.9 2.9 2.4 1.6 28.2 2.6 2.7 0.7 5.8 9.2 2.7 2.7 4.3 3.4 2.6 24.2 7.9 1.2 2.9 4.4 6.9 4.6 4.5 4.1 10.5 20.1 3.2 2.1 3.0 21.7 5.6 1.6 3.4 3.2 6.9 1.4 1.4 3.0 5.6 12.9 1.7 6.1 17.6 5.0 8.6 7.2 5.7 11.0 23.1 10.8 2.3 4.5 13.4 10.1 2.2 0.6 17.9 14.8 2.2 3.3 2.2 2.4 9.8 3.8 2.7 13.8 14.3 17.7 1.8 11.3 6.8 7.1 12.8 6.4 4.4 13.4 6.4 24.4 5.5 5.7 12.0 9.2 4.5 3.0 1.1 9.8 16.8 13.3 10.4 8.1 2.3 2.5 4.1 10.0 2.3 2.3 4.3 2.7 2.7 2.2 2.3 2.9 33.6 6.4 8.6 17.0 120.2 50.2 73.3 85.1 51.2 55.4 42.9 49.1 6.1 47.1 37.4 47.8 20.9 120.6 61.8 36.6 84.1 94.6 42.6 40.9 54.9 37.4 71.8 57.8 14.1 77.1 228.1 46.2 41.8 41.1 34.8 112.2 41.0 20.3 76.1 67.3 18.4 54.6 99.7 23.0 41.7 18.9 35.8 36.5 56.9 15.9 51.2 92.4 45.3 17.1 18.1 74.7 53.1 32.0 139.6 74.4 41.9 86.4 28.5 49.6 19.7 47.7 62.8 138.9 163.3 64.5 53.0 160.1 42.0 96.8 65.4 65.1 SMARCD1 "BAF60A, CRACD1, Rsc6p" ENSG00000066117 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" Q96GM5 12 50085200-50100707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Chromatin regulator" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004101 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA004101: AB_1080026" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "prognostic unfavorable (2.53e-8)" "unprognostic (3.62e-2)" "unprognostic (1.44e-1)" "unprognostic (4.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-3)" "unprognostic (2.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.38e-1)" "unprognostic (5.04e-2)" 25.8 28.1 25.2 23.2 27.6 44.0 24.9 24.4 27.0 23.5 20.8 22.0 23.2 27.9 27.1 27.5 23.8 17.9 18.3 26.3 23.8 25.3 19.0 23.9 35.0 25.7 25.7 26.4 22.5 47.3 19.7 28.9 25.3 23.2 27.2 25.1 24.3 21.8 16.9 24.3 27.8 28.8 24.8 31.3 20.5 23.8 25.8 57.2 26.8 16.1 47.6 23.5 21.7 27.6 28.4 47.6 134.8 75.8 41.1 38.9 68.1 35.1 62.0 100.3 58.2 130.0 42.1 109.4 51.0 67.2 44.4 35.4 112.9 91.5 87.3 84.4 87.0 107.2 49.4 75.8 49.3 95.0 41.1 40.2 60.2 59.8 107.4 66.1 119.5 114.0 93.1 64.8 50.6 67.7 137.6 54.0 166.0 43.2 76.6 165.5 34.9 96.0 57.3 66.1 71.4 121.3 73.1 35.2 139.3 100.4 79.4 78.7 70.4 50.1 56.0 31.7 69.9 91.6 88.2 95.4 40.6 37.7 56.9 3.4 1.2 2.2 2.9 1.2 2.9 3.6 1.6 2.0 1.8 2.7 1.0 3.3 0.5 1.7 1.9 3.5 2.7 1.2 25.2 27.6 24.4 27.0 26.3 23.8 25.7 25.7 25.3 24.8 25.8 27.6 29.7 0.0 9.6 11.1 42.9 16.6 22.3 17.7 42.7 33.7 33.2 30.2 6.5 15.7 20.5 27.6 20.9 21.1 39.6 21.6 52.8 32.8 4.3 20.0 36.9 30.1 31.1 25.7 9.3 29.0 19.4 17.8 14.8 30.5 16.5 40.0 17.5 15.1 17.3 26.9 10.5 18.2 10.2 14.4 13.1 9.1 16.4 16.8 17.8 7.5 27.1 26.5 29.9 11.1 17.1 36.8 14.8 16.1 28.9 28.8 19.5 47.9 9.4 28.8 32.9 31.6 28.2 28.4 36.5 31.3 19.6 11.1 30.0 26.8 19.1 15.9 SMARCE1 BAF57 ENSG00000073584 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1" Q969G3 17 40624962-40648654 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" Neurogenesis "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003916, CAB037318" Supported Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB037318: AB_476780, HPA003916: AB_1857279" "unprognostic (7.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.09e-2)" "unprognostic (8.06e-3)" "unprognostic (1.87e-1)" "unprognostic (2.55e-2)" "unprognostic (4.48e-1)" "unprognostic (1.25e-2)" "unprognostic (2.20e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-2)" "unprognostic (2.04e-1)" "unprognostic (9.80e-2)" "unprognostic (5.93e-2)" "unprognostic (7.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-2)" 39.4 22.2 10.5 37.8 11.9 43.2 35.6 10.6 13.3 45.9 14.3 40.2 38.9 56.2 28.3 43.6 39.0 41.4 40.1 9.2 11.7 31.2 31.5 36.1 49.6 13.7 10.7 58.6 35.4 38.3 13.3 48.4 13.2 34.2 38.5 17.5 33.6 42.1 42.5 27.7 39.3 57.4 11.7 40.5 30.9 31.5 11.2 76.1 40.8 44.7 54.2 46.8 26.2 16.5 86.5 139.6 169.1 126.5 87.7 125.5 82.8 105.9 145.4 122.1 91.0 92.7 72.7 135.9 149.6 145.3 81.0 114.5 106.1 112.3 145.1 128.3 138.0 97.2 73.4 165.2 87.8 179.8 94.5 109.3 87.6 97.7 140.6 122.1 133.4 106.5 144.2 52.2 118.2 96.5 331.6 37.1 95.4 70.8 68.6 183.3 190.2 103.7 147.5 144.9 134.6 130.0 94.5 269.4 86.6 181.5 161.5 111.4 109.7 98.1 107.6 89.7 132.6 97.7 122.8 204.5 100.0 80.9 154.9 106.3 64.4 88.2 91.7 67.8 95.0 99.8 82.4 96.1 77.9 112.3 68.3 79.3 26.5 124.7 82.2 80.3 114.7 112.2 10.5 11.9 10.6 13.3 9.2 11.7 13.7 10.7 13.2 11.7 11.2 16.5 41.4 48.1 45.1 13.1 67.5 38.1 43.0 69.5 65.4 75.8 19.7 20.2 53.0 38.6 61.5 20.2 16.7 101.8 68.7 38.7 15.6 41.5 27.1 34.9 47.0 60.4 96.5 84.1 17.1 32.3 75.7 72.4 44.9 32.1 74.0 41.3 62.8 44.0 51.6 82.4 18.8 53.5 65.1 42.9 39.6 11.8 90.4 30.9 24.9 19.7 63.2 63.3 105.0 26.7 32.7 35.7 46.7 82.4 44.2 36.5 52.8 30.5 59.3 37.1 39.5 62.7 57.0 49.7 50.9 63.3 40.1 114.8 53.8 35.3 62.5 34.3 SMC1A "DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb" ENSG00000072501 "Structural maintenance of chromosomes 1A" Q14683 X 53374149-53422728 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005499, CAB025404" Supported Enhanced Nucleoplasm NA NA 33000 "Cluster 27: Non-specific - Gene expression" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB025404: , HPA005499: AB_1080028" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (4.00e-2)" "unprognostic (5.76e-2)" "unprognostic (1.04e-1)" "unprognostic (9.89e-2)" "unprognostic (1.29e-3)" "unprognostic (1.89e-1)" "unprognostic (9.80e-3)" "unprognostic (9.49e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-2)" "unprognostic (2.58e-1)" "unprognostic (4.18e-3)" "unprognostic (6.28e-2)" "unprognostic (2.89e-1)" "unprognostic (9.39e-2)" 16.6 11.8 8.7 28.4 11.7 30.3 17.2 15.0 9.5 13.8 9.6 20.0 18.6 21.0 8.0 17.1 16.7 11.5 15.6 7.8 9.5 16.3 18.8 16.0 34.4 10.2 10.7 19.1 14.4 25.8 6.3 18.2 10.7 14.0 18.4 21.0 15.1 13.0 17.9 18.1 15.9 22.9 8.7 20.1 15.7 7.8 11.3 58.1 16.8 18.8 29.9 15.5 12.4 13.9 110.0 115.1 92.4 76.1 32.4 35.4 51.5 68.0 37.0 76.4 59.4 71.6 60.5 115.8 54.1 40.7 105.2 78.9 162.9 92.6 85.1 91.7 176.0 94.3 133.9 51.1 15.4 134.9 120.9 20.6 23.3 86.0 52.8 19.4 67.5 68.7 144.7 64.7 58.6 69.2 122.0 40.8 139.9 47.8 55.6 117.2 165.5 100.1 34.4 69.4 92.8 83.5 176.9 84.4 33.5 122.8 87.9 54.0 45.7 63.3 68.0 65.1 62.2 45.8 77.9 91.9 39.1 152.1 64.1 2.7 6.8 4.5 7.3 8.5 7.6 5.4 5.8 6.7 8.4 5.8 5.2 6.3 2.7 4.6 12.4 4.6 5.7 6.7 8.7 11.7 15.0 9.5 7.8 9.5 10.2 10.7 10.7 8.7 11.3 13.9 40.7 44.8 39.9 16.0 45.6 24.1 37.0 27.7 28.5 46.6 30.7 27.4 63.5 27.1 47.4 20.2 27.1 43.2 57.7 49.6 7.9 31.6 10.5 46.5 62.6 41.7 19.9 70.7 12.0 27.1 61.4 37.2 29.0 44.0 35.4 42.7 18.9 54.1 47.6 60.6 14.2 43.5 22.4 41.1 27.6 7.6 37.9 51.5 23.2 24.4 55.2 38.1 59.8 16.6 30.2 33.1 23.6 36.1 61.2 40.7 29.0 24.6 47.1 48.4 39.5 49.5 71.0 54.5 51.2 39.8 24.4 48.4 47.9 34.0 51.4 32.0 SMC3 "BAM, bamacan, CSPG6, HCAP, SMC3L1" ENSG00000108055 "Structural maintenance of chromosomes 3" Q9UQE7 10 110567695-110606048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Spermatocytes: 994.2;Spermatogonia: 799.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043206 Approved Supported Nucleoplasm NA NA 630000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "HPA043206: AB_2678362" "unprognostic (3.40e-1)" "unprognostic (1.73e-2)" "unprognostic (9.05e-2)" "unprognostic (3.00e-2)" "unprognostic (3.73e-2)" "unprognostic (8.89e-3)" "unprognostic (9.74e-3)" "unprognostic (8.06e-2)" "unprognostic (5.31e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (1.17e-2)" "unprognostic (8.73e-3)" "unprognostic (7.22e-2)" "unprognostic (5.18e-2)" "unprognostic (7.95e-2)" "unprognostic (1.32e-1)" 19.5 13.3 9.0 18.7 10.9 43.9 19.1 18.5 11.7 18.5 11.7 18.3 15.5 20.3 15.7 19.2 16.5 11.1 12.9 8.6 10.2 14.0 15.3 14.5 25.2 10.2 9.4 25.7 19.6 20.0 14.2 20.7 10.4 14.0 16.7 27.6 16.2 15.2 21.1 20.6 19.4 16.9 9.6 18.6 14.7 38.1 9.5 39.2 16.5 14.1 24.3 15.5 17.8 12.7 73.1 44.5 95.4 67.8 30.7 26.3 40.9 57.7 56.7 51.9 50.7 56.4 59.7 94.2 24.5 38.6 40.0 56.5 68.7 35.0 78.6 77.3 60.1 76.5 56.2 51.2 30.8 109.8 56.6 21.1 28.0 57.4 89.5 48.5 38.8 31.7 61.7 70.4 45.4 38.1 85.2 58.3 66.1 38.6 35.1 71.1 171.5 51.4 32.4 31.7 53.7 61.8 62.0 17.7 48.6 61.8 28.5 53.1 40.1 41.6 65.5 47.6 84.4 40.9 38.8 99.6 37.5 103.9 34.8 20.7 6.1 15.8 9.6 8.4 12.1 11.0 11.3 10.6 6.8 11.0 11.3 11.2 6.5 12.6 7.6 8.7 14.5 6.2 9.0 10.9 18.5 11.7 8.6 10.2 10.2 9.4 10.4 9.6 9.5 12.7 74.9 80.1 62.0 16.6 73.5 60.5 53.2 64.1 34.7 81.3 44.3 49.9 64.5 47.1 64.4 55.2 75.0 119.6 94.3 29.8 25.4 96.9 56.9 52.0 65.0 74.9 40.7 104.6 26.2 45.6 111.4 66.0 20.9 49.0 56.3 124.9 40.4 31.9 59.1 60.6 29.2 40.7 54.9 37.9 42.5 34.6 115.2 49.8 37.4 19.7 96.1 54.9 98.9 33.2 43.4 53.0 70.1 114.0 65.0 44.7 70.7 30.3 68.3 78.9 184.1 102.0 110.6 994.2 799.1 48.1 64.5 49.1 80.9 112.7 51.9 37.5 SMO "FZD11, SMOH" ENSG00000128602 "Smoothened, frizzled class receptor" Q99835 7 129188633-129213545 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 27.4;Granulosa cells: 13.0;Leydig cells: 20.8;Muller glia cells: 16.6;Peritubular cells: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 45.3;AN3-CA: 84.9;NTERA-2: 64.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011446 Approved NA NA "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "CAB011446: " "unprognostic (2.48e-2)" "unprognostic (2.69e-2)" "unprognostic (7.09e-2)" "unprognostic (1.10e-1)" "unprognostic (8.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.38e-3)" "unprognostic (1.59e-1)" "unprognostic (1.17e-2)" "unprognostic (8.74e-3)" "unprognostic (1.62e-1)" "unprognostic (5.15e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-1)" "unprognostic (2.61e-2)" 5.2 6.0 9.4 2.6 10.8 0.4 5.5 9.9 9.6 27.4 18.4 9.6 2.5 19.2 18.6 12.0 14.5 8.4 8.0 8.9 10.0 19.0 23.9 3.6 2.2 12.4 12.4 28.3 6.3 16.1 19.2 2.6 9.9 20.0 2.1 2.0 11.5 12.3 3.7 17.1 5.7 8.1 11.8 2.8 6.3 5.6 11.4 4.4 9.1 3.7 2.0 9.0 16.7 9.7 1.6 18.2 45.3 84.9 1.1 0.2 14.3 5.2 6.7 10.1 5.8 13.8 0.1 0.0 13.9 10.4 22.8 28.3 27.4 1.5 3.9 0.0 23.0 9.4 0.0 22.5 5.5 0.4 0.0 16.2 11.0 3.3 0.0 19.9 5.8 24.9 1.5 0.0 3.1 0.0 24.4 0.1 64.2 0.0 5.3 35.1 19.7 0.0 5.2 0.0 1.3 30.2 0.0 0.0 12.3 16.8 11.1 5.8 0.0 0.7 14.1 17.6 10.1 0.6 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 10.8 9.9 9.6 8.9 10.0 12.4 12.4 9.9 11.8 11.4 9.7 0.4 0.0 0.0 27.4 0.2 1.9 2.3 3.9 2.8 0.7 3.3 5.2 1.4 2.8 3.8 11.0 0.0 0.3 0.4 0.0 1.9 3.4 0.4 1.0 8.6 0.6 0.0 0.0 1.4 1.1 0.3 7.6 0.0 1.3 0.0 13.0 1.4 8.4 4.2 0.0 0.8 0.1 2.0 1.6 1.8 1.3 20.8 1.0 0.0 3.7 0.6 16.6 0.0 4.5 0.5 1.3 0.1 21.8 0.0 2.7 0.0 3.9 0.7 0.4 6.6 3.5 3.9 0.0 2.0 3.3 2.8 0.5 0.1 6.9 0.6 0.7 SMYD3 "KMT3E, ZMYND1, ZNFN3A1" ENSG00000185420 "SET and MYND domain containing 3" Q9H7B4 1 245749342-246507312 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 406.1;Excitatory neurons: 725.6;Inhibitory neurons: 788.3;Microglial cells: 277.3;Oligodendrocyte precursor cells: 372.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 402.2;K-562: 162.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012229, HPA045821, HPA054352" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB012229: , HPA045821: AB_2679461, HPA054352: AB_2682458" "unprognostic (7.00e-3)" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (6.18e-3)" "unprognostic (3.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.25e-3)" "unprognostic (1.72e-3)" "unprognostic (4.53e-2)" "unprognostic (1.57e-1)" "unprognostic (1.71e-1)" "unprognostic (2.10e-1)" "unprognostic (3.78e-5)" "unprognostic (9.03e-3)" "unprognostic (2.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.58e-1)" 7.9 12.1 9.5 5.0 9.6 9.7 11.1 16.4 9.6 9.1 5.8 7.5 5.0 7.1 22.1 6.4 10.3 8.2 6.7 10.4 10.2 9.4 6.0 9.8 7.7 7.0 10.3 8.2 7.8 9.5 9.2 5.3 9.8 6.8 8.8 7.0 6.6 5.4 11.6 8.0 6.0 6.7 4.4 5.7 7.3 8.7 11.6 10.8 16.0 9.8 7.7 10.1 5.9 6.8 20.8 12.6 17.8 15.4 19.9 27.1 17.3 28.7 21.4 33.4 74.4 16.2 23.7 33.5 22.6 27.0 20.8 13.2 16.3 32.1 111.3 17.7 16.4 20.0 17.9 19.5 37.3 20.1 402.2 73.5 7.6 44.3 28.5 25.3 23.1 23.5 162.0 11.5 33.0 7.0 38.8 38.8 15.9 29.1 19.5 35.5 21.3 48.9 24.5 29.3 41.9 19.8 13.5 2.0 26.4 19.3 16.5 33.8 17.6 15.9 11.0 11.4 34.8 57.0 16.7 17.3 30.5 27.3 18.8 13.1 4.6 11.5 12.9 4.1 13.7 14.2 13.7 16.4 8.0 15.8 15.1 16.1 3.2 27.5 4.6 5.0 16.2 12.1 9.5 9.6 16.4 9.6 10.4 10.2 7.0 10.3 9.8 4.4 11.6 6.8 14.2 6.4 30.7 406.1 16.2 12.2 14.7 26.5 13.1 7.7 8.7 9.3 9.1 4.3 18.9 12.9 22.9 8.1 15.8 5.1 15.6 22.3 54.8 24.9 14.3 12.7 25.1 6.3 725.6 31.1 42.6 15.9 9.2 13.6 110.9 25.7 12.5 4.9 12.3 10.1 788.3 7.9 26.4 4.1 10.2 110.9 11.1 6.0 12.4 277.3 3.7 7.6 16.5 372.4 136.5 24.0 3.7 17.3 19.9 4.8 4.0 19.3 36.9 13.2 0.0 12.1 20.7 19.6 27.5 12.0 11.5 7.3 18.3 46.3 8.8 10.0 SND1 "p100, TDRD11" ENSG00000197157 "Staphylococcal nuclease and tudor domain containing 1" Q7KZF4 7 127652194-128092609 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Endonuclease, Hydrolase, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 255.0;Syncytiotrophoblasts: 267.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002529, HPA002632, CAB019323" Enhanced Enhanced Cytosol NA NA 1800000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB019323: , HPA002529: AB_1857317, HPA002632: AB_1857316" "unprognostic (2.06e-1)" "unprognostic (8.27e-3)" "unprognostic (2.21e-1)" "prognostic favorable (1.95e-4)" "unprognostic (5.10e-3)" "unprognostic (6.83e-2)" "unprognostic (1.17e-2)" "unprognostic (2.91e-2)" "unprognostic (4.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (2.30e-1)" "unprognostic (1.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.42e-2)" "unprognostic (2.26e-3)" 48.5 52.5 19.1 57.8 22.6 65.8 56.7 25.3 21.4 76.9 41.0 51.3 54.2 67.2 90.6 47.7 65.1 37.3 45.3 19.9 33.3 33.9 67.5 46.7 53.0 29.7 29.4 87.3 179.0 50.8 52.7 86.7 29.9 59.0 49.4 32.1 102.2 57.7 41.9 43.7 45.3 66.5 26.2 45.8 65.7 38.5 25.4 67.5 66.0 40.0 65.3 50.0 41.8 33.5 160.0 141.8 106.3 193.5 156.6 162.7 145.3 183.5 214.8 163.8 182.5 184.6 134.6 210.6 90.4 225.7 137.8 130.4 150.7 198.1 158.6 116.1 127.2 116.1 153.0 177.9 284.2 181.9 109.6 241.3 216.3 140.0 232.3 185.7 206.2 85.1 131.3 204.9 165.0 118.6 199.5 135.6 119.5 159.7 173.6 136.8 94.6 476.1 128.1 110.5 133.0 143.7 132.8 606.6 217.5 157.8 76.2 127.2 207.3 132.3 86.4 243.3 144.7 250.1 101.1 217.0 265.6 153.6 245.2 49.7 86.4 17.1 67.0 76.6 78.0 70.1 50.0 54.0 87.4 44.6 34.9 39.8 6.2 59.7 66.1 92.9 43.4 92.9 19.1 22.6 25.3 21.4 19.9 33.3 29.7 29.4 29.9 26.2 25.4 33.5 20.3 16.0 44.7 60.4 56.7 19.6 24.7 32.9 22.2 17.1 41.0 28.6 29.2 35.8 28.9 29.5 20.9 255.0 44.3 28.8 17.6 62.8 20.1 21.9 51.9 30.3 73.1 47.5 128.0 96.7 106.1 40.7 54.6 39.5 34.9 54.4 25.0 49.8 81.9 30.3 116.0 59.4 18.3 52.8 36.7 68.1 45.7 50.8 33.8 78.7 72.5 16.7 32.0 84.9 89.9 58.6 29.8 41.3 124.6 42.8 38.2 33.1 19.0 32.7 32.9 27.0 34.4 23.4 28.0 37.6 27.4 267.6 37.2 74.0 58.3 27.0 SNX25 SBBI31 ENSG00000109762 "Sorting nexin 25" Q9H3E2 4 185204237-185370185 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 128.9;Astrocytes: 50.6;Excitatory neurons: 57.7;Inhibitory neurons: 60.7;Oligodendrocyte precursor cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036928 Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA036928: AB_10669720" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (4.29e-3)" "unprognostic (8.89e-2)" "unprognostic (5.63e-2)" "unprognostic (1.43e-2)" "unprognostic (6.41e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-2)" "unprognostic (4.03e-3)" "unprognostic (1.87e-1)" "unprognostic (3.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (8.55e-3)" 7.6 8.0 7.0 7.3 8.4 2.0 9.5 17.3 7.9 6.0 23.9 12.3 3.5 6.9 6.3 7.1 9.7 8.5 8.7 7.5 8.9 11.3 9.1 29.1 11.5 9.6 10.0 7.4 10.0 13.3 10.5 11.8 9.7 14.9 6.7 25.5 6.7 8.6 10.2 6.2 7.9 7.0 8.1 9.5 6.2 12.7 8.8 2.9 16.7 8.6 12.9 7.2 5.4 7.3 11.9 6.2 7.8 11.0 20.5 15.0 11.5 35.6 17.1 17.9 14.9 5.3 8.1 33.6 3.8 26.0 12.4 4.6 8.9 7.8 20.0 55.9 14.5 5.7 7.5 12.8 11.9 3.8 8.0 10.4 8.3 15.6 8.6 36.0 15.7 6.3 12.0 33.3 23.9 3.5 1.5 6.9 6.3 1.6 5.9 4.9 9.0 8.6 43.0 4.5 16.5 11.9 7.4 2.0 30.3 10.8 4.2 4.9 30.0 10.2 6.5 9.8 15.7 29.3 12.8 7.1 16.7 2.8 12.9 0.0 0.0 0.0 0.1 0.0 0.3 0.7 0.3 0.4 0.0 1.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 7.0 8.4 17.3 7.9 7.5 8.9 9.6 10.0 9.7 8.1 8.8 7.3 9.5 25.6 128.9 50.6 12.6 4.8 4.2 2.3 4.6 15.9 7.0 3.4 6.8 0.0 7.3 5.5 31.3 4.8 5.5 5.4 0.0 4.8 5.9 11.5 8.1 9.6 0.0 0.0 57.7 2.6 4.9 4.9 5.1 10.3 1.3 3.9 12.5 8.8 2.0 6.7 60.7 4.0 2.0 3.2 2.5 4.8 9.6 2.2 21.4 32.8 0.6 5.6 3.1 55.3 21.4 3.9 1.6 9.8 11.3 9.4 5.6 2.3 6.7 15.7 0.0 4.8 5.7 9.0 16.2 2.3 6.1 5.6 7.0 10.3 3.3 5.5 SOCS1 "Cish1, JAB, SOCS-1, SSI-1, TIP3" ENSG00000185338 "Suppressor of cytokine signaling 1" O15524 16 11254408-11256204 "Cancer-related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 102.5;dendritic cells: 191.9;T-cells: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 13.6" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "HDLM-2: 107.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010355, HPA074108" Approved Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Cytoplasmic bodies" "CAB010355: AB_2193144, HPA074108: AB_2686661" "unprognostic (4.50e-3)" "unprognostic (3.30e-2)" "unprognostic (1.24e-1)" "unprognostic (1.66e-2)" "unprognostic (1.25e-2)" "prognostic favorable (1.10e-4)" "unprognostic (1.71e-2)" "unprognostic (4.09e-3)" "unprognostic (5.31e-3)" "unprognostic (4.82e-2)" "unprognostic (1.17e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (1.08e-6)" "unprognostic (1.56e-1)" "unprognostic (5.68e-2)" "unprognostic (6.08e-2)" "unprognostic (1.67e-1)" 10.7 4.2 0.9 14.3 1.0 9.9 6.9 5.8 1.1 15.6 0.7 5.0 2.0 5.9 1.1 5.4 4.6 2.3 5.1 0.9 1.3 23.2 26.9 9.7 13.5 2.5 1.2 9.4 3.1 0.7 14.8 3.8 2.7 6.3 0.9 0.1 4.9 1.7 2.1 7.4 12.4 1.0 1.9 18.6 8.0 7.6 2.6 9.8 4.4 0.5 10.2 6.6 7.0 1.0 2.8 0.5 1.1 0.2 3.3 0.5 4.0 2.2 15.7 1.0 1.3 0.7 0.5 6.3 4.7 1.0 2.9 1.1 0.4 0.2 0.2 107.8 0.8 1.7 0.0 8.6 1.4 0.0 18.5 1.4 0.3 2.2 0.2 0.4 0.3 0.6 14.4 1.8 0.1 2.5 7.2 4.0 11.4 0.2 1.7 0.7 0.7 0.7 1.2 0.5 1.5 0.2 0.5 3.7 1.2 3.1 0.0 0.9 0.1 1.3 6.4 0.9 1.5 0.4 0.6 10.0 2.6 0.8 1.3 13.6 0.1 10.2 2.1 0.0 1.9 1.5 2.4 2.6 0.0 5.3 2.6 2.3 0.3 6.1 0.1 1.3 2.8 0.4 0.9 1.0 5.8 1.1 0.9 1.3 2.5 1.2 2.7 1.9 2.6 1.0 102.5 0.0 4.4 1.6 67.7 12.2 17.4 1.9 8.6 1.9 33.8 55.5 10.3 2.8 0.7 51.5 6.2 24.1 191.9 30.6 23.5 18.4 64.8 18.1 19.9 14.3 26.0 8.4 0.0 8.5 4.8 61.5 26.0 36.9 52.8 4.9 8.2 3.4 4.5 0.0 0.2 17.7 8.2 5.8 25.7 24.7 7.2 33.8 30.2 1.0 14.2 6.7 24.7 0.5 0.0 5.0 20.2 41.8 89.0 7.4 19.0 9.2 2.5 4.8 0.0 30.2 34.2 0.8 8.3 10.1 6.8 57.7 161.5 23.0 11.8 11.6 SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659666-31668931 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1645.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 3357.9;Proximal tubular cells: 3285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 44900000 50000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Plasma membrane, Cytosol" "CAB008670: AB_1623312, HPA001401: AB_1080132" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (4.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.39e-1)" "unprognostic (9.59e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (5.28e-2)" "unprognostic (9.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (3.26e-2)" 257.6 597.1 558.0 118.4 577.4 166.4 233.5 605.2 805.1 206.6 586.6 251.0 360.3 179.5 228.4 221.1 197.1 206.0 477.3 575.1 619.9 483.2 1645.6 153.9 169.6 619.8 604.6 302.1 117.1 210.6 236.7 155.8 653.1 203.9 180.5 248.6 160.5 204.2 428.0 152.1 266.7 136.6 588.1 147.5 210.4 132.1 585.8 165.7 197.4 355.9 151.7 232.1 220.6 634.7 526.8 451.4 309.2 312.8 407.3 282.1 257.8 430.2 258.0 291.3 217.4 593.6 326.0 628.2 441.2 405.8 517.7 186.1 453.3 320.6 239.9 463.3 540.0 1008.2 579.5 866.3 267.4 451.7 363.1 294.8 240.6 406.5 225.2 327.9 331.2 469.0 704.4 773.2 357.4 860.0 489.0 454.5 466.1 830.0 475.4 413.0 622.0 981.4 579.4 320.5 335.9 281.4 805.1 419.4 438.3 279.2 484.3 393.4 387.4 222.9 489.2 304.7 322.0 583.4 1374.2 741.8 455.7 654.3 301.9 204.2 159.7 194.0 313.4 234.0 365.3 427.1 509.2 402.4 212.8 310.1 521.8 412.1 37.8 241.4 465.4 240.6 746.0 474.5 558.0 577.4 605.2 805.1 575.1 619.9 619.8 604.6 653.1 588.1 585.8 634.7 319.8 294.9 175.1 38.2 248.1 491.4 672.7 479.2 319.8 226.6 264.1 352.9 721.0 527.6 294.7 391.8 47.9 703.4 250.2 703.5 1631.7 426.3 277.0 410.7 241.2 261.0 288.4 898.8 39.7 807.3 574.9 365.8 198.8 216.3 220.0 278.9 318.1 3357.9 363.3 282.7 45.5 402.7 366.2 220.0 318.5 952.2 521.9 224.2 419.8 29.0 313.1 598.5 239.0 28.6 68.7 322.8 600.9 528.1 178.2 567.0 1158.3 3285.9 638.3 216.5 440.4 313.6 404.5 211.7 506.3 379.9 349.8 725.9 423.1 470.3 593.6 497.7 SOD2 GClnc1 ENSG00000112096 "Superoxide dismutase 2" P04179 6 159669069-159762529 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 1083.7;skeletal muscle: 3230.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2508.2;Prostatic glandular cells: 3524.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 4470.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 4470.5" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1611.9;GAMG: 614.3;HSkMC: 688.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001814, CAB002013" Supported Enhanced Mitochondria NA NA 55000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "CAB002013: , HPA001814: AB_1080134" "unprognostic (2.47e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-1)" "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "unprognostic (1.69e-1)" "unprognostic (1.49e-1)" "unprognostic (3.10e-2)" "unprognostic (1.37e-1)" "unprognostic (6.67e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (8.12e-2)" "unprognostic (4.14e-2)" "unprognostic (5.99e-2)" "unprognostic (1.82e-1)" 324.8 245.9 66.8 522.8 43.2 1083.7 169.0 37.8 125.8 92.6 99.7 126.4 60.5 105.4 7.2 136.5 118.5 121.8 178.5 37.0 101.0 252.4 459.8 266.5 64.8 250.0 96.1 55.8 212.3 69.1 42.7 62.9 192.9 130.8 37.9 25.1 328.8 43.9 3230.1 90.0 83.7 108.4 62.5 81.4 120.4 39.6 153.1 38.2 67.2 312.6 65.0 514.9 97.9 85.4 35.8 46.3 37.3 85.1 229.0 378.7 20.5 52.7 1611.9 57.7 131.1 91.3 19.4 70.7 144.5 54.1 614.3 58.9 39.1 42.5 42.4 71.2 87.2 74.5 71.8 152.3 169.5 74.0 31.9 688.9 68.5 180.9 133.6 40.7 30.0 44.9 106.7 82.2 55.4 37.6 60.3 46.6 63.3 41.5 55.4 79.6 50.3 63.9 106.2 56.6 71.5 29.5 105.1 52.4 21.4 14.1 33.1 33.7 30.4 168.6 62.1 92.5 87.9 37.8 100.2 86.5 186.7 57.4 23.6 146.3 364.4 181.1 38.8 273.9 43.4 43.4 54.9 38.5 105.2 38.3 45.0 36.9 4470.5 19.1 445.3 14.8 87.9 340.0 66.8 43.2 37.8 125.8 37.0 101.0 250.0 96.1 192.9 62.5 153.1 85.4 303.2 201.9 746.1 13.4 99.0 684.7 1144.9 2508.2 114.4 45.6 150.2 96.6 0.0 287.4 613.3 237.3 45.9 18.3 43.8 153.9 86.1 1400.2 318.2 281.7 649.8 593.0 79.6 101.2 31.1 1389.7 51.2 1098.4 103.5 1080.1 112.3 23.1 58.9 395.0 292.0 32.0 30.1 92.7 339.7 333.3 1425.8 111.5 58.1 1031.2 521.2 15.9 339.9 50.4 35.0 8.5 12.2 581.6 111.3 65.1 101.2 3524.0 128.6 530.1 269.6 61.8 39.5 1164.0 407.3 91.7 51.4 258.7 681.8 27.2 119.4 38.3 148.1 1195.7 SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38981549-39124345 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 226.6;Inhibitory neurons: 224.0;Microglial cells: 161.1;Oligodendrocyte precursor cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 134.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005396 Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB005396: AB_2270724" "unprognostic (6.68e-2)" "unprognostic (2.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.14e-3)" "unprognostic (4.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.74e-3)" "unprognostic (4.55e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-3)" "unprognostic (7.61e-2)" "unprognostic (5.59e-2)" "unprognostic (1.33e-2)" 17.5 8.4 8.2 14.8 10.2 10.8 9.8 14.1 10.3 13.1 6.8 11.0 14.7 14.3 10.3 12.3 11.2 13.5 9.5 9.7 10.8 11.0 11.9 11.0 16.9 9.5 10.2 20.1 9.1 17.1 0.1 17.0 9.5 13.4 12.9 13.2 9.0 12.2 13.7 9.4 15.6 13.8 6.7 12.5 11.5 10.3 8.7 15.4 15.1 16.4 17.8 13.5 0.1 10.6 24.8 15.1 22.8 16.2 29.1 35.0 23.8 15.3 18.7 12.0 11.4 16.3 14.6 35.8 10.3 20.1 18.5 14.4 26.9 13.9 22.1 36.3 11.9 55.5 12.8 22.0 11.8 17.9 134.9 21.6 20.5 16.3 15.8 19.5 18.9 8.1 23.9 16.4 15.4 13.5 19.4 15.8 14.3 30.4 10.4 21.5 20.5 10.5 12.1 19.8 22.0 22.0 18.3 32.3 18.2 18.5 10.4 9.3 21.5 19.8 16.0 15.7 15.4 19.3 20.9 18.4 15.8 17.3 12.0 0.0 0.5 1.4 1.3 0.7 1.9 1.6 1.3 1.4 0.4 1.0 1.5 1.4 0.6 2.7 0.9 0.6 0.9 0.4 8.2 10.2 14.1 10.3 9.7 10.8 9.5 10.2 9.5 6.7 8.7 10.6 72.3 16.0 31.2 120.5 20.9 20.8 15.5 10.9 19.9 19.0 18.4 16.9 33.9 18.6 17.8 9.2 10.4 10.2 27.6 19.5 1.9 11.0 64.9 30.0 36.6 43.2 12.0 12.8 226.6 11.9 8.4 22.9 21.4 34.0 3.8 30.0 12.8 18.6 10.3 8.4 224.0 16.9 26.4 19.1 13.2 11.4 22.7 19.9 7.2 161.1 19.6 15.1 26.8 173.4 125.2 14.2 14.6 21.8 37.5 25.3 28.0 12.8 20.4 11.2 6.6 27.1 22.7 11.3 7.0 17.1 25.3 10.4 33.2 18.4 17.0 28.4 SOX1 ENSG00000182968 "SRY-box transcription factor 1" O00570 13 112067149-112071706 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "brain: 14.8" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 4.0;Melanocytes: 3.6;Spermatogonia: 2.4" "Group enriched" "Detected in some" 6 "colorectal cancer: 0.9;glioma: 2.3;melanoma: 2.0" "Region enhanced" "Detected in all" "thalamus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 29.3" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.12e-1)" "unprognostic (4.95e-2)" "unprognostic (1.71e-3)" "unprognostic (6.03e-2)" "unprognostic (6.41e-2)" "unprognostic (4.85e-1)" "unprognostic (5.93e-2)" 0.0 0.0 2.1 0.0 3.7 0.0 0.0 1.3 2.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.3 0.0 0.0 0.0 0.0 1.8 4.1 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.8 14.8 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 3.7 1.3 2.7 1.6 5.3 1.8 4.1 2.1 1.2 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.1" "Group enriched" "Detected in many" 8 "Adipocytes: 464.9;Endometrial ciliated cells: 377.3;Endothelial cells: 171.5;Glandular and luminal cells: 520.0" "Group enriched" "Detected in many" 4 "endometrial cancer: 122.8;ovarian cancer: 96.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "EFO-21: 108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB025594: , HPA068399: AB_2685981" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favorable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" 49.1 1.6 2.9 1.4 2.3 0.0 32.6 2.6 3.3 20.4 1.4 8.3 0.7 18.8 1.2 3.6 23.0 7.7 19.1 2.1 2.2 5.6 1.3 9.9 0.7 2.9 2.5 4.2 1.9 0.8 2.3 5.7 2.7 6.0 0.8 0.1 3.9 1.1 10.3 5.1 5.0 4.3 2.5 13.2 5.7 3.4 2.8 0.4 5.8 5.8 0.4 8.4 9.4 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 2.6 3.3 2.1 2.2 2.9 2.5 2.7 2.5 2.8 2.6 464.9 0.0 0.0 0.0 0.2 13.9 0.3 0.0 0.0 0.1 0.7 1.3 2.1 1.5 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 2.6 377.3 44.5 171.5 0.0 2.7 0.0 0.2 0.1 7.7 0.0 520.0 0.0 0.0 46.8 0.1 0.1 0.0 0.0 0.0 0.0 0.9 16.6 1.8 2.5 3.5 19.6 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 7.3 5.1 3.2 6.4 0.3 13.5 0.0 4.5 0.2 0.0 3.7 SOX2 ENSG00000181449 "SRY-box transcription factor 2" P48431 3 181711925-181714436 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.2;esophagus: 24.5" "Group enriched" "Detected in some" 6 "Basal squamous epithelial cells: 362.0;Muller glia cells: 383.5;Squamous epithelial cells: 229.1" "Cancer enhanced" "Detected in many" "glioma: 136.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 277.0;HAP1: 118.6;NTERA-2: 226.2;U-251 MG: 54.0" "Low region specificity" "Detected in all" "HPA045725, HPA062851, HPA071379, CAB079745" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB079745: , HPA045725: AB_2679431, HPA062851: , HPA071379: " "unprognostic (1.80e-2)" "unprognostic (3.18e-3)" "unprognostic (5.69e-2)" "unprognostic (6.96e-2)" "unprognostic (2.74e-3)" "unprognostic (1.60e-1)" "unprognostic (1.79e-2)" "unprognostic (4.48e-3)" "unprognostic (1.71e-1)" "unprognostic (4.38e-3)" "unprognostic (1.83e-1)" "unprognostic (7.68e-2)" "unprognostic (3.81e-9)" "unprognostic (1.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.12e-2)" 0.3 0.9 58.0 0.5 58.5 0.0 0.2 47.1 56.6 2.1 8.6 5.5 0.4 0.1 0.2 24.5 3.1 0.2 0.5 46.5 59.0 0.0 0.1 1.8 0.0 50.5 58.9 0.3 0.1 0.0 13.6 0.0 45.2 2.5 0.4 15.0 18.4 0.3 0.1 0.6 1.4 0.2 59.8 0.0 7.9 1.9 59.2 0.4 0.1 0.1 5.3 1.3 4.8 62.2 0.1 9.0 277.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.3 0.0 0.1 0.0 0.2 0.7 118.6 3.2 0.0 0.1 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 226.2 12.4 0.5 0.0 0.6 0.0 31.0 0.4 0.5 1.2 0.0 0.0 0.1 45.7 1.7 0.1 0.0 0.0 4.2 0.0 54.0 0.0 0.0 0.0 0.2 0.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.0 58.5 47.1 56.6 46.5 59.0 50.5 58.9 45.2 59.8 59.2 62.2 0.2 0.0 6.0 0.0 0.0 0.3 35.5 28.5 362.0 4.9 0.2 0.4 0.5 0.0 48.4 3.7 0.0 0.2 0.0 1.1 0.0 0.0 0.9 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.1 1.6 19.4 0.0 1.3 0.2 0.7 0.1 0.1 0.0 0.0 0.5 38.7 0.0 0.4 0.4 0.6 0.8 3.6 0.0 0.0 383.5 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 0.0 0.1 52.8 13.1 0.0 0.2 1.6 3.9 0.4 229.1 0.4 0.3 0.6 0.2 0.0 7.5 SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.7;salivary gland: 80.1" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Basal squamous epithelial cells: 166.8;Breast glandular cells: 141.0;Cholangiocytes: 190.1;Gastric mucus-secreting cells: 144.8;Muller glia cells: 141.3;Squamous epithelial cells: 273.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 78.1;Hep G2: 97.0;OE19: 74.3;U-251 MG: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB022456: , CAB068240: AB_2665670, HPA001758: AB_1080067" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (4.47e-3)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (7.96e-3)" "unprognostic (4.32e-3)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.92e-3)" "unprognostic (1.21e-1)" "unprognostic (3.26e-3)" "unprognostic (2.77e-3)" "unprognostic (1.15e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-2)" 3.1 2.2 54.7 4.4 50.4 0.1 28.0 42.3 58.5 7.4 46.8 17.1 19.7 2.9 0.9 13.7 7.5 13.0 15.8 50.6 49.3 12.7 3.5 3.1 1.1 73.7 72.2 0.3 38.4 0.1 10.3 0.3 48.8 24.8 17.8 15.0 80.1 10.9 2.7 23.3 15.1 1.2 56.9 0.2 40.5 30.7 51.4 0.5 20.2 1.2 4.4 1.9 6.4 49.0 31.1 19.2 38.9 78.1 3.9 1.1 0.1 4.8 4.2 8.2 4.4 27.0 40.8 0.0 2.9 1.1 43.8 31.3 0.0 18.6 7.5 0.0 2.5 0.0 4.2 97.0 0.3 0.0 0.1 0.7 1.6 9.5 9.0 47.0 0.0 0.0 0.0 0.1 11.7 0.4 0.0 0.1 1.5 74.3 29.1 0.0 31.4 0.4 35.2 2.0 1.9 1.9 4.0 4.7 0.1 21.0 16.7 0.2 0.0 15.8 42.0 8.5 66.5 0.0 0.0 0.1 11.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.4 42.3 58.5 50.6 49.3 73.7 72.2 48.8 56.9 51.4 49.0 1.1 12.8 5.6 160.0 1.9 55.4 88.2 28.9 166.8 3.0 141.0 108.2 13.6 190.1 21.1 36.8 0.0 0.3 2.8 52.1 7.9 55.3 5.1 18.4 0.9 3.2 59.7 0.0 3.1 46.7 0.0 26.0 144.8 21.7 4.5 1.9 0.0 3.4 0.2 0.0 1.5 99.0 24.4 0.0 3.4 14.5 4.4 2.3 12.4 9.4 1.0 141.3 0.0 4.5 11.1 40.8 39.1 0.4 2.8 81.1 17.7 61.0 36.4 6.8 6.6 59.9 14.5 10.2 3.1 273.5 17.8 0.1 2.8 0.1 103.8 77.2 SP1 ENSG00000185591 "Sp1 transcription factor" P08047 12 53380176-53416446 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000330, HPA001853, HPA012292" Supported Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 52: Non-specific - Ribosome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB000330: AB_2171049, HPA001853: AB_1080069, HPA012292: AB_1857394" "unprognostic (1.12e-1)" "unprognostic (8.52e-3)" "unprognostic (6.11e-2)" "unprognostic (1.24e-1)" "unprognostic (2.03e-1)" "unprognostic (4.64e-3)" "unprognostic (1.08e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-1)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (6.38e-2)" "unprognostic (5.14e-2)" "unprognostic (4.05e-2)" "unprognostic (1.37e-1)" "unprognostic (4.77e-2)" "unprognostic (2.12e-2)" 23.6 18.6 10.7 23.1 15.1 29.9 26.2 20.3 12.5 23.7 11.6 24.8 30.9 29.8 21.0 38.6 25.5 25.6 13.4 10.6 11.7 20.7 17.0 22.8 24.2 16.4 14.0 29.8 18.6 22.1 10.7 23.7 16.2 20.8 29.8 20.4 27.5 22.0 25.2 40.1 31.2 26.4 13.0 28.0 28.6 19.4 13.5 36.7 19.6 25.8 30.2 24.2 25.3 17.6 34.2 31.3 40.5 31.2 34.7 39.4 32.1 23.1 29.0 27.2 26.9 27.9 70.3 43.9 29.3 27.1 18.3 49.2 43.6 32.9 33.0 31.3 23.8 38.5 48.2 18.3 24.3 39.4 33.1 40.3 36.4 27.0 53.9 55.1 31.0 35.5 37.6 63.8 23.1 50.2 53.9 31.9 22.4 28.0 25.0 37.8 38.5 28.5 25.7 57.8 21.0 30.5 47.7 42.9 26.8 33.5 52.3 42.6 29.5 35.3 30.3 26.4 25.3 21.3 25.4 42.5 26.3 29.9 28.2 3.1 2.6 1.6 1.3 1.7 1.6 1.4 1.3 1.3 1.5 1.5 1.4 1.5 6.9 1.0 1.9 1.8 1.1 1.0 10.7 15.1 20.3 12.5 10.6 11.7 16.4 14.0 16.2 13.0 13.5 17.6 29.7 22.4 15.0 13.1 18.5 23.8 19.9 22.4 33.6 10.6 28.3 19.4 8.2 24.3 26.8 31.3 8.4 16.2 16.6 55.8 5.9 16.1 64.1 21.8 23.4 24.7 12.6 25.2 7.7 13.8 16.3 21.5 23.9 34.7 6.3 17.2 28.2 28.4 18.2 16.8 7.2 29.8 6.1 38.6 16.1 50.3 27.4 24.5 8.8 16.9 42.2 22.7 18.6 12.5 20.4 18.8 21.0 25.9 12.0 35.4 34.8 20.8 23.9 10.8 13.1 31.4 21.0 29.4 22.1 44.2 31.3 21.3 14.8 11.7 26.2 47.7 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4430.9;Endothelial cells: 2372.1;Peritubular cells: 2523.5;Sertoli cells: 4674.1;Skeletal myocytes: 2379.0;Smooth muscle cells: 2781.9" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 24.9;SuSa: 31.4;U-266/70: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Enhanced "Secreted in other tissues" NA NA 630000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" 755.6 129.5 664.6 124.5 810.9 0.5 532.1 612.4 1058.4 732.7 580.4 624.3 125.1 1244.5 443.8 308.1 754.5 487.9 600.2 744.6 723.5 72.5 25.0 481.1 99.1 655.7 730.9 286.8 91.8 128.0 197.8 315.4 663.4 584.2 187.5 95.2 228.3 999.2 244.8 130.2 280.1 1191.2 774.7 157.9 347.7 97.5 694.8 103.2 369.9 594.7 100.0 488.0 466.4 681.2 0.7 0.0 24.9 0.3 0.2 0.1 2.6 0.1 0.1 0.0 0.0 0.0 0.1 0.4 1.8 0.0 0.0 1.4 2.4 0.0 0.0 1.7 0.0 0.3 1.1 0.4 1.1 0.3 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.5 0.2 3.5 0.6 0.0 0.0 0.3 0.4 1.2 0.0 0.1 0.8 1.6 0.1 0.2 0.1 31.4 0.4 0.5 0.0 0.2 0.3 1.5 0.2 9.1 1.4 0.6 3.4 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 664.6 810.9 612.4 1058.4 744.6 723.5 655.7 730.9 663.4 774.7 694.8 681.2 4430.9 12.8 56.4 1155.7 6.2 46.3 187.2 0.6 59.7 10.7 24.4 251.6 334.2 4.3 43.3 7.3 2.1 2.2 8.6 0.0 13.7 0.8 11.8 34.9 935.8 2372.1 0.0 32.0 382.3 0.4 3.2 1413.1 6.1 46.7 7.6 1.4 899.5 9.1 9.2 3.3 450.1 0.0 0.0 5.3 55.2 47.0 659.5 31.6 56.9 261.4 0.0 179.4 0.0 210.6 53.8 0.1 0.0 2523.5 25.2 50.4 0.0 24.6 7.4 34.4 4674.1 2379.0 2781.9 5.7 7.9 56.8 39.9 2.5 26.9 38.8 0.0 124.2 SPATA6 "FLJ10007, SRF-1, SRF1" ENSG00000132122 "Spermatogenesis associated 6" Q9NWH7 1 48295373-48472208 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 50.1" "Group enriched" "Detected in many" 5 "Early spermatids: 1475.4;Late spermatids: 4697.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.9" "Group enriched" "Detected in many" 4 "granulocytes: 3.6;monocytes: 5.9" "Cell line enhanced" "Detected in many" "AN3-CA: 12.9;ASC TERT1: 20.9;HSkMC: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028234 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA028234: AB_2672532" "unprognostic (1.36e-2)" "unprognostic (2.96e-2)" "unprognostic (3.38e-2)" "unprognostic (2.87e-2)" "unprognostic (3.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.77e-2)" "unprognostic (4.69e-3)" "unprognostic (2.40e-2)" "unprognostic (2.61e-2)" "unprognostic (8.41e-2)" "unprognostic (6.50e-2)" "unprognostic (3.41e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (7.89e-2)" "unprognostic (5.71e-3)" 6.0 8.1 6.2 2.0 9.7 1.0 7.2 6.9 6.4 7.8 7.2 5.2 2.7 5.8 6.1 3.4 15.3 4.9 4.4 5.9 8.0 6.1 1.7 5.9 2.2 8.6 8.5 8.9 4.6 10.6 8.6 4.7 8.6 5.4 3.9 13.3 6.3 7.4 1.7 4.4 3.3 4.4 7.3 3.7 6.7 50.1 9.6 3.2 9.5 3.7 1.6 6.0 6.3 11.9 0.2 1.2 11.6 12.9 10.5 20.9 1.6 1.3 4.9 0.9 0.8 0.1 0.8 0.0 0.7 2.1 6.1 0.3 0.9 2.9 0.8 0.9 1.6 0.1 0.5 0.6 2.2 0.0 0.8 15.0 2.2 1.9 0.7 6.3 4.7 1.8 0.1 0.0 4.9 0.4 0.1 0.2 4.9 0.9 1.2 3.7 0.0 1.1 7.1 2.0 2.8 6.3 4.8 0.4 11.3 9.5 2.8 0.7 1.4 1.7 1.7 2.7 1.9 0.0 0.0 0.0 7.0 0.1 7.7 0.0 1.2 3.6 0.0 2.8 0.0 0.1 0.2 0.0 1.1 0.0 0.4 0.3 0.1 0.2 5.9 0.5 0.0 0.5 6.2 9.7 6.9 6.4 5.9 8.0 8.6 8.5 8.6 7.3 9.6 11.9 14.8 3.2 10.0 151.8 2.0 5.6 16.7 6.4 9.1 17.0 13.1 19.9 3.5 28.6 12.5 16.5 45.9 0.4 5.1 3.9 17.6 8.9 1475.4 77.3 18.9 10.5 9.6 2.1 43.9 10.2 0.6 29.8 35.2 9.0 16.5 5.0 16.1 2.4 5.1 32.0 35.0 5.7 12.2 17.9 9.2 4697.2 36.7 14.9 19.6 68.4 10.5 23.4 3.1 563.5 341.6 4.5 3.8 25.2 2.0 6.2 3.4 10.3 67.3 45.7 19.7 47.5 14.7 110.5 23.8 6.7 5.3 0.3 1.6 11.5 5.7 9.7 SPEN "KIAA0929, MINT, RBM15C, SHARP" ENSG00000065526 "Spen family transcriptional repressor" Q96T58 1 15836095-15940456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015825, HPA050257" Supported Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA015825: AB_1856823, HPA050257: AB_2681065" "unprognostic (3.91e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (3.06e-2)" "unprognostic (6.93e-3)" "unprognostic (2.26e-1)" "unprognostic (4.26e-2)" "unprognostic (4.88e-3)" "unprognostic (1.71e-1)" "unprognostic (5.98e-2)" "unprognostic (1.06e-3)" "unprognostic (1.49e-1)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (1.83e-1)" 15.3 8.6 11.3 11.5 14.6 23.2 14.0 22.6 12.9 13.3 4.8 12.0 8.8 14.4 8.5 13.3 15.5 8.0 10.8 10.4 14.6 9.6 11.0 14.8 12.9 14.2 12.4 21.3 17.5 16.4 10.7 11.8 11.4 11.1 9.1 15.1 12.8 9.9 20.5 17.3 13.4 9.8 8.0 12.7 11.0 10.3 12.6 16.6 15.6 19.8 13.3 13.0 13.6 20.7 25.4 20.9 26.1 19.6 25.0 15.2 13.8 12.9 16.6 13.5 11.4 19.3 19.5 35.6 15.0 25.1 15.9 36.0 24.0 22.6 21.4 32.1 68.5 44.6 20.5 12.4 11.3 37.1 20.8 11.2 15.9 20.2 28.9 12.9 15.5 26.5 47.1 35.9 11.1 14.0 30.7 14.7 11.6 14.4 15.9 29.5 25.1 21.9 7.5 22.4 20.5 19.9 36.2 17.4 14.8 11.6 6.5 18.4 28.9 12.8 15.5 24.4 18.5 21.5 15.0 39.6 12.2 29.2 17.9 7.4 1.9 1.6 1.4 1.7 0.9 1.3 1.1 1.0 0.5 3.0 0.9 1.0 8.5 1.1 1.3 2.8 0.9 0.5 11.3 14.6 22.6 12.9 10.4 14.6 14.2 12.4 11.4 8.0 12.6 20.7 55.7 80.1 85.3 68.9 69.4 104.6 44.9 18.3 90.5 67.1 35.0 27.9 52.6 30.0 43.2 5.5 52.1 12.2 52.8 44.4 3.9 18.5 7.0 90.4 67.4 51.6 31.7 47.1 57.2 17.6 15.0 45.9 41.8 146.5 62.6 34.3 20.0 32.6 15.2 95.9 66.0 27.4 8.2 34.6 69.6 4.9 27.4 53.2 21.4 64.6 56.3 28.3 68.0 51.8 88.7 23.6 34.6 35.7 74.5 46.7 16.8 7.5 29.4 53.2 19.7 85.7 56.6 59.5 45.9 89.8 101.6 15.7 52.3 33.1 32.8 56.3 SPINK1 "PCTT, PSTI, Spink3, TATI" ENSG00000164266 "Serine peptidase inhibitor Kazal type 1" P00995 5 147824572-147831671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "pancreas: 53063.4" "Group enriched" "Detected in many" 9 "Exocrine glandular cells: 50621.7;Pancreatic endocrine cells: 16750.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 513.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "CACO-2: 417.2;RT4: 1139.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026366, HPA027498" Enhanced "Secreted to digestive system" NA NA 8000000 "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB026366: , HPA027498: AB_10603115" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (9.96e-3)" "unprognostic (3.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.79e-4)" "unprognostic (8.34e-3)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "unprognostic (1.88e-1)" "unprognostic (3.82e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.44e-7)" "unprognostic (7.98e-2)" "unprognostic (2.07e-1)" "prognostic favorable (2.15e-5)" 8.8 1.5 0.1 36.4 0.1 6.8 4.1 0.3 1.2 3.1 0.3 428.2 394.4 5.5 0.8 2.9 1.3 111.9 12.0 0.2 0.2 142.5 491.8 2.7 2.7 0.1 0.1 25.6 53063.4 0.0 1.9 3.2 0.2 4.4 441.3 0.6 12.8 1.4 1.2 21.1 403.9 14.1 0.0 2.5 1475.2 0.9 0.3 0.4 1.0 0.0 0.3 995.6 10.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.2 0.0 0.0 417.2 0.3 0.1 6.8 0.0 0.8 0.9 2.2 0.0 0.0 3.9 0.0 0.0 0.0 107.0 0.3 0.0 3.9 0.0 2.1 0.0 3.0 5.8 0.0 0.0 0.0 0.3 0.0 0.3 0.8 1.3 2.1 138.9 0.8 0.8 0.0 2.5 0.0 1139.0 0.5 1.7 0.0 0.2 0.1 5.4 0.1 0.0 0.0 0.1 13.7 1.1 3.8 2.2 5.9 3.0 16.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 1.2 0.2 0.2 0.1 0.1 0.2 0.0 0.3 0.6 0.0 0.0 3.6 0.0 9.7 0.0 15.1 0.3 0.0 0.0 5.5 0.8 0.1 1451.2 11.1 377.0 0.0 0.0 0.0 280.8 86.1 1286.7 0.1 0.3 0.4 9.4 517.2 18.7 1.0 50621.7 0.1 1.9 1580.5 5.0 4.5 2.0 39.3 3385.8 0.1 0.0 0.2 2087.4 0.0 30.9 0.0 0.2 0.0 13.7 0.0 0.0 269.8 0.0 0.0 0.0 0.1 16750.7 563.8 0.0 1.3 173.5 1457.1 1.6 0.7 0.0 0.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 1365.3 649.1 SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1254.0;Distal enterocytes: 477.6;Proximal enterocytes: 514.5;Syncytiotrophoblasts: 1673.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 323.2;HaCaT: 377.6;hTCEpi: 264.0;RT4: 308.2;SK-BR-3: 558.8;T-47d: 267.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" 2.8 0.7 0.9 16.4 1.5 1.4 34.7 5.0 1.3 42.8 6.4 108.7 159.9 13.2 78.9 255.5 33.6 38.0 1.3 0.9 2.0 79.9 3.5 47.6 6.4 2.8 3.2 2.4 69.2 132.9 31.4 144.9 2.2 52.3 89.2 0.4 162.7 31.4 0.6 148.9 138.2 4.3 1.7 6.9 88.3 1.8 3.2 9.9 34.7 0.4 45.5 57.1 90.1 2.3 124.8 1.0 0.0 0.9 0.1 0.0 323.2 2.3 3.0 4.0 2.4 195.3 202.4 0.3 141.2 0.4 3.6 377.6 30.8 181.9 2.4 1.0 10.6 5.6 3.3 10.8 2.2 21.9 93.9 0.3 264.0 3.9 16.5 3.4 14.7 12.1 2.7 1.1 0.2 96.5 0.9 16.6 37.4 207.6 17.7 12.6 0.0 24.9 179.3 308.2 79.8 3.9 9.3 558.8 15.7 56.9 267.7 16.1 0.0 0.2 2.0 1.2 0.5 1.2 24.5 0.8 0.8 16.3 1.1 0.0 19.7 14.3 0.4 15.9 0.8 8.4 3.0 1.4 32.4 6.0 1.1 0.3 25.9 5.5 18.1 4.0 0.5 7.6 0.9 1.5 5.0 1.3 0.9 2.0 2.8 3.2 2.2 1.7 3.2 2.3 0.8 57.7 14.7 0.0 7.6 76.0 96.7 220.0 55.8 0.1 96.2 63.5 0.5 105.8 207.3 134.3 0.0 1254.0 1.4 477.6 25.4 429.4 0.8 63.3 14.2 6.9 147.3 4.8 0.5 255.1 105.1 10.4 106.5 155.6 10.2 1.9 0.4 0.5 135.4 0.0 0.5 169.4 221.8 10.0 23.8 1.1 3.7 19.8 14.2 0.0 68.6 0.0 0.0 0.0 0.0 309.8 375.2 0.0 2.1 135.7 514.5 44.2 46.6 0.3 0.0 0.1 12.6 0.6 5.9 93.2 87.9 1673.8 6.6 0.1 182.7 222.3 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 SPOP "BTBD32, TEF2" ENSG00000121067 "Speckle type BTB/POZ protein" O43791 17 49598884-49678163 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (8.83e-2)" "unprognostic (3.23e-1)" "unprognostic (2.15e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (1.89e-2)" "unprognostic (7.20e-2)" "unprognostic (1.17e-2)" "unprognostic (1.51e-2)" "unprognostic (1.24e-3)" "unprognostic (7.67e-2)" "unprognostic (2.81e-1)" "unprognostic (3.45e-2)" "unprognostic (1.10e-2)" "unprognostic (3.29e-1)" 32.3 26.8 33.4 28.7 37.6 13.6 30.2 49.8 39.8 45.7 35.9 92.2 27.4 50.1 35.8 56.9 42.2 29.8 41.0 36.1 37.3 29.5 37.1 33.1 38.9 33.1 34.0 40.9 25.1 30.9 22.7 32.5 34.6 64.8 39.2 38.2 32.8 81.7 57.2 26.5 34.0 77.8 31.8 32.8 35.0 17.0 38.4 43.6 35.2 52.4 42.8 46.7 30.6 42.8 33.7 30.9 40.9 18.3 49.0 51.8 28.0 44.1 47.6 57.6 62.8 71.1 36.8 56.4 84.2 41.3 38.5 29.2 49.3 29.1 68.8 111.4 57.6 70.6 38.9 47.8 54.6 45.9 50.3 39.0 41.4 42.9 46.2 43.1 60.9 39.6 73.3 54.2 42.4 33.3 79.2 44.0 11.4 80.9 46.3 48.8 64.5 79.9 32.9 21.0 65.2 26.7 29.7 14.1 37.2 22.5 54.2 45.8 55.4 65.9 41.0 49.9 39.5 52.3 51.7 50.6 37.6 41.0 32.9 145.3 71.2 93.0 61.3 68.7 59.8 76.4 66.0 68.9 91.8 80.2 98.2 78.9 107.9 74.9 88.8 67.9 63.9 92.4 33.4 37.6 49.8 39.8 36.1 37.3 33.1 34.0 34.6 31.8 38.4 42.8 54.5 48.1 41.6 80.6 59.2 42.8 36.2 26.7 34.7 72.7 44.5 38.7 51.6 35.8 30.4 29.5 43.8 23.3 47.3 25.9 29.4 36.5 24.4 30.3 38.8 57.5 51.5 53.2 50.5 28.2 23.3 55.9 18.8 28.4 31.0 39.2 66.8 47.3 38.5 75.7 50.1 46.2 30.5 62.2 59.4 8.9 56.2 49.0 39.2 45.9 67.7 100.2 33.0 54.3 49.3 25.6 30.5 73.4 61.4 30.6 40.1 29.6 32.4 58.7 72.3 37.1 59.2 36.6 45.8 28.2 43.9 36.1 46.7 50.1 33.3 22.8 SPP1 "BNSP, BSPI, ETA-1, OPN" ENSG00000118785 "Secreted phosphoprotein 1" P10451 4 87975650-87983426 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Biomineralization, Cell adhesion" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 2424.4;kidney: 3587.6;placenta: 2791.9" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 60702.5" "Group enriched" "Detected in all" 4 "glioma: 1690.9;renal cancer: 1385.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "neutrophil: 24.8" "Lineage enriched" "Detected in single" 249 "granulocytes: 24.8" "Cell line enhanced" "Detected in many" "EFO-21: 4825.8;Hep G2: 2469.7;RPTEC TERT1: 10348.3" "Region enhanced" "Detected in all" "pons and medulla: 316.8" "Low region specificity" "Detected in all" "HPA027540, HPA027541" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" NA NA 114000000 73000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "HPA027540: AB_10600222, HPA027541: AB_10601446" "unprognostic (4.74e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.13e-3)" "unprognostic (2.04e-1)" "unprognostic (2.31e-2)" "unprognostic (6.96e-3)" "prognostic unfavorable (2.84e-6)" "unprognostic (2.46e-3)" "unprognostic (7.86e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (4.31e-2)" "unprognostic (2.55e-1)" "unprognostic (7.19e-2)" "unprognostic (1.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.63e-2)" 113.1 24.4 276.0 59.5 490.3 1.0 70.2 652.0 736.4 27.5 265.0 44.9 9.5 131.2 9.8 4.8 52.8 2424.4 37.0 301.6 417.1 3587.6 35.6 18.8 9.1 813.2 645.3 9.9 292.0 19.2 20.6 2791.9 781.8 15.7 7.6 745.5 88.7 22.1 16.0 2.7 14.4 38.3 472.6 9.2 11.0 11.7 633.1 8.4 8.3 0.4 5.7 25.0 6.0 855.0 2.2 144.0 19.1 1.1 0.0 0.2 0.3 5.6 4.4 1.4 9.1 0.6 0.2 0.2 4825.8 2.3 371.5 1.4 0.0 0.0 3.1 11.2 0.0 0.0 1.8 2469.7 0.3 6.8 5.1 0.5 0.3 34.9 0.1 118.8 4.2 0.2 0.1 10.8 1.3 0.2 1.2 21.3 227.5 0.3 0.0 2.4 0.5 1189.8 10348.3 1.8 1.1 0.9 0.3 0.8 339.1 441.9 0.5 5.2 0.3 11.5 27.1 0.4 25.8 0.9 7.9 13.9 436.3 1.1 457.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 276.0 490.3 652.0 736.4 301.6 417.1 813.2 645.3 781.8 472.6 633.1 855.0 35.7 3.2 4.7 5.2 34.0 1.5 5.2 0.1 1.2 46.6 1767.7 22.4 17.9 1584.2 0.3 2183.1 27.1 335.6 6.9 0.0 1003.7 7273.8 0.1 61.2 25.2 367.9 0.0 2.7 1.4 71.7 294.5 48.9 0.0 154.2 0.0 1.7 5.7 5.0 60702.5 785.7 9.9 0.0 0.0 57.4 7.7 1.0 0.9 247.7 1.8 99.3 69.2 3862.9 0.0 4.5 532.1 215.4 0.0 0.0 0.1 0.4 0.0 5594.0 1.6 169.7 0.0 0.9 21.6 0.5 0.2 1.1 1.0 667.8 30.0 0.4 0.0 9.9 SPRR1B "GADD33, SPRR1" ENSG00000169469 "Small proline rich protein 1B" P22528 1 153031203-153032900 "Cancer-related genes, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1386.5;esophagus: 2237.9;vagina: 1775.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 100.1;Club cells: 167.8;Pancreatic endocrine cells: 67.1;Suprabasal keratinocytes: 380.9;Urothelial cells: 94.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 1812.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "hTCEpi: 364.3" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.73e-1)" "unprognostic (2.39e-1)" "unprognostic (5.59e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (7.66e-5)" "unprognostic (2.22e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (7.64e-5)" "unprognostic (5.71e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.28e-4)" 0.9 0.6 0.0 0.0 0.0 0.3 6.9 0.0 0.0 1386.5 0.0 0.4 0.0 0.6 0.2 2237.9 0.7 16.9 1.0 0.0 0.0 0.5 1.3 0.5 0.0 0.0 0.0 0.8 1.4 0.0 0.9 0.1 0.0 0.6 0.0 0.0 735.5 0.0 1.4 542.0 0.6 0.5 0.0 0.5 1.6 0.4 0.0 7.5 0.6 0.0 447.7 10.7 1775.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.6 0.0 0.0 0.0 39.5 0.0 5.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 364.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.0 2.4 100.1 0.0 0.0 0.0 0.0 0.0 0.0 167.8 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.7 0.0 8.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 67.1 2.2 0.0 0.0 0.6 0.0 0.0 10.7 0.0 0.0 0.0 5.8 0.0 0.0 14.9 380.9 0.3 0.3 0.0 0.0 94.7 SPRR3 ENSG00000163209 "Small proline rich protein 3" Q9UBC9 1 153001747-153003856 "Cancer-related genes, Predicted intracellular proteins" Keratinization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 4257.2;esophagus: 19480.4;vagina: 6062.0" "Cell type enriched" "Detected in some" 11 "Squamous epithelial cells: 987.1" "Group enriched" "Detected in many" 4 "cervical cancer: 206.3;head and neck cancer: 423.4;stomach cancer: 113.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.5;CAPAN-2: 5.8;hTCEpi: 9.7;OE19: 4.4;RT4: 12.6;TIME: 3.4" "Not detected" "Not detected" HPA044467 Enhanced NA NA 5200 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA044467: AB_2678952" "unprognostic (2.78e-2)" "unprognostic (3.54e-1)" "unprognostic (8.77e-2)" "unprognostic (7.50e-3)" "unprognostic (9.67e-3)" "unprognostic (2.36e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (9.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.58e-2)" 4.0 3.5 0.0 0.1 0.0 0.0 3.0 0.0 0.0 4257.2 0.0 2.6 0.1 3.5 0.0 19480.4 3.4 38.1 7.4 0.0 0.0 2.6 5.8 1.7 0.0 0.0 0.0 4.4 8.8 0.0 11.0 0.7 0.0 3.4 0.1 0.0 3157.9 0.0 5.0 7.5 4.2 1.7 0.0 3.4 15.2 2.1 0.0 1.4 2.3 0.0 2399.3 65.1 6062.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 3.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.3 0.0 0.0 0.0 4.4 0.0 0.0 1.1 0.0 0.0 12.6 0.0 0.0 0.3 2.7 0.0 0.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 1.5 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 4.0 7.4 0.0 0.0 0.0 0.1 0.0 41.3 0.0 0.0 5.9 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 4.2 1.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.3 0.0 0.0 0.0 0.4 0.0 0.1 2.1 0.0 0.0 0.0 1.0 0.0 0.0 987.1 0.0 7.5 0.4 0.1 0.0 89.6 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 42.0;Gastric mucus-secreting cells: 43.8;Langerhans cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;monocytes: 2.4" "Cell line enhanced" "Detected in many" "A549: 110.8;HBEC3-KT: 102.6;RT4: 106.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA 3200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cell Junctions" "Nucleoplasm, Cytosol" "CAB004023: AB_2106059, HPA030875: AB_2673640" "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.63e-4)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favorable (5.22e-5)" 9.7 25.3 5.7 13.3 5.2 8.4 10.1 0.4 6.2 25.1 1.5 30.3 39.8 31.9 3.2 26.1 23.8 27.9 8.8 6.4 5.5 21.4 4.3 16.1 6.3 2.6 3.4 23.6 30.8 11.1 15.9 8.1 2.2 30.8 17.1 5.5 11.8 27.4 2.4 13.0 38.8 17.2 1.7 14.2 39.9 25.2 5.0 6.1 9.8 1.5 8.1 35.6 24.6 3.0 24.6 110.8 24.9 22.6 9.3 14.7 51.6 22.0 18.9 26.3 16.6 41.9 21.5 0.7 13.4 40.2 29.9 43.5 15.1 102.6 10.3 0.1 13.7 6.2 3.9 65.9 22.0 0.3 9.3 15.7 34.2 17.3 22.8 29.4 24.3 14.2 0.6 0.2 4.4 16.7 6.0 0.8 11.7 67.3 98.8 26.5 6.6 0.7 11.0 106.3 23.1 83.6 25.0 34.5 27.2 19.1 31.1 9.0 35.8 31.4 20.9 11.7 20.1 0.3 0.8 0.3 22.1 0.1 24.0 0.0 1.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 2.3 1.4 0.0 1.0 5.7 5.2 0.4 6.2 6.4 5.5 2.6 3.4 2.2 1.7 5.0 3.0 1.0 3.2 1.7 3.3 4.1 8.2 12.5 9.5 10.8 6.5 6.2 7.5 2.2 18.6 4.7 12.9 2.1 2.3 4.9 42.0 1.9 12.2 1.8 6.4 10.7 1.4 16.8 0.4 9.5 18.7 8.3 7.2 43.8 12.4 0.0 14.8 1.1 1.6 5.7 3.3 9.1 29.2 8.2 9.4 46.3 3.3 10.8 22.8 1.8 9.4 9.7 4.4 1.0 9.0 0.6 39.1 19.2 17.3 4.3 18.0 36.7 9.3 5.6 5.2 13.1 1.8 6.7 0.3 1.1 11.2 9.1 2.3 1.0 2.9 16.9 36.6 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 1.5 2.0 4.7 1.9 5.3 2.2 11.0 7.4 8.8 3.9 0.1 2.4 4.1 1.7 3.0 11.0 1.7 1.7 1.0 5.5 3.2 4.6 29.0 1.9 2.3 6.0 3.3 2.5 2.3 1.4 1.1 1.0 6.3 1.5 2.3 3.8 2.7 1.1 1.3 13.6 4.1 1.6 1.8 1.4 2.5 1.5 6.9 1.6 1.3 0.7 4.1 1.1 6.6 8.3 5.2 6.1 8.0 6.7 7.6 7.3 3.5 5.7 4.5 5.7 3.5 6.0 5.3 7.1 8.1 8.7 9.1 9.8 6.6 4.0 6.0 4.3 2.6 2.2 15.3 3.7 3.4 3.3 1.8 5.4 11.3 4.1 3.2 4.2 2.9 2.7 3.7 6.2 7.5 7.1 1.4 3.6 4.5 4.1 4.7 5.1 5.8 2.0 7.6 5.4 14.0 6.4 18.2 7.6 5.8 6.1 2.6 0.9 5.8 8.6 3.4 14.2 7.6 2.3 3.6 2.6 7.2 3.6 8.0 3.5 1.3 0.5 0.3 1.0 0.2 0.5 0.3 0.5 1.6 0.6 0.2 0.3 0.7 0.5 1.1 0.7 0.4 0.5 4.7 5.3 7.4 8.8 5.5 3.2 6.0 3.3 6.3 1.8 6.9 8.3 3.7 3.2 2.7 7.8 11.9 18.5 6.7 19.0 67.2 5.0 14.5 9.1 2.6 11.5 12.8 5.5 4.2 0.9 5.0 8.3 7.9 9.8 8.1 2.6 4.3 3.2 2.4 4.4 15.5 4.7 7.4 4.7 16.3 3.2 1.3 6.0 4.6 103.4 13.0 6.7 14.9 7.2 52.9 19.4 11.6 2.6 3.4 11.6 7.2 6.5 50.7 5.1 10.3 9.0 7.6 6.7 10.4 7.9 7.2 9.4 24.9 23.4 10.4 3.8 0.0 3.7 6.1 3.4 4.4 139.2 30.4 0.8 5.9 5.2 12.0 10.2 SRD5A2 ENSG00000277893 "Steroid 5 alpha-reductase 2" P31213 2 31522480-31580938 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 23.5;fallopian tube: 20.4;liver: 60.8;prostate: 16.8;seminal vesicle: 18.0" "Group enriched" "Detected in some" 5 "Early spermatids: 71.7;Endometrial ciliated cells: 29.6;Hepatocytes: 20.0;Late spermatids: 59.9" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.1;liver cancer: 4.2;prostate cancer: 3.2" "Region enriched" "Detected in single" 11 "midbrain: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.75e-3)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-3)" "unprognostic (5.92e-3)" "unprognostic (3.37e-2)" "unprognostic (2.79e-3)" "unprognostic (6.56e-2)" "unprognostic (9.10e-2)" "unprognostic (1.39e-2)" "unprognostic (3.06e-2)" "unprognostic (9.79e-3)" "unprognostic (6.61e-6)" "unprognostic (4.37e-2)" "unprognostic (2.04e-1)" "unprognostic (3.85e-1)" "unprognostic (3.48e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 23.5 0.0 20.4 0.0 0.0 0.0 0.0 0.3 60.8 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.1 0.0 18.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.2 0.0 0.0 0.0 1.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.7 29.6 0.2 0.2 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.5 0.0 0.0 0.4 20.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 59.9 0.6 0.1 0.0 3.7 0.0 0.0 0.0 0.5 0.9 0.1 0.0 1.2 0.0 0.7 0.0 0.3 7.3 0.0 0.0 0.0 0.2 1.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 8.6 SRSF2 "PR264, SC-35, SC35, SFRS2, SFRS2A" ENSG00000161547 "Serine and arginine rich splicing factor 2" Q01130 17 76734115-76737333 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049905 Supported Approved Nucleoplasm,Cytosol NA NA 180000 "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA049905: AB_2680945" "unprognostic (2.50e-1)" "unprognostic (2.16e-3)" "unprognostic (2.73e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "prognostic unfavorable (3.53e-8)" "unprognostic (1.19e-1)" "unprognostic (7.79e-3)" "unprognostic (7.03e-3)" "unprognostic (1.92e-1)" "unprognostic (1.07e-3)" "prognostic unfavorable (1.05e-7)" "unprognostic (3.85e-2)" "unprognostic (8.05e-2)" "unprognostic (1.95e-1)" "prognostic favorable (9.87e-4)" 106.0 106.8 27.8 95.5 29.6 184.7 92.1 29.9 34.0 83.6 37.7 100.3 86.2 88.9 64.0 129.5 89.5 42.1 78.5 29.2 32.9 83.0 115.2 95.4 111.6 30.8 28.5 85.6 88.3 48.4 81.9 66.0 30.3 78.0 71.6 53.4 90.6 52.3 91.7 96.5 113.2 49.0 31.3 121.6 94.4 49.5 30.0 94.2 102.1 36.0 100.2 80.0 94.3 36.0 318.7 239.8 289.5 207.5 70.9 58.5 300.5 197.3 146.8 225.4 207.0 257.2 216.8 478.0 143.3 188.7 164.3 279.9 293.3 229.0 230.2 202.3 489.3 357.9 246.6 311.9 79.3 404.4 210.6 65.2 51.1 186.2 54.0 91.1 179.9 212.0 373.4 209.6 183.7 251.0 460.0 440.9 339.5 186.4 340.2 455.0 310.6 360.5 156.5 225.2 247.7 350.8 227.1 196.3 120.4 154.0 238.8 301.6 187.9 206.9 271.3 139.4 330.0 278.2 219.2 552.9 187.3 318.9 177.1 2.5 40.9 10.0 26.0 53.3 26.0 23.5 17.7 26.7 67.0 19.6 20.1 19.4 4.4 35.6 33.6 49.2 24.0 33.0 27.8 29.6 29.9 34.0 29.2 32.9 30.8 28.5 30.3 31.3 30.0 36.0 271.3 118.6 105.6 57.5 396.7 460.8 439.7 205.9 540.1 151.9 291.7 277.9 86.2 148.7 141.5 88.3 91.8 339.4 548.0 233.1 156.5 199.1 203.6 176.8 181.9 204.3 266.3 366.6 51.1 157.3 579.7 233.9 196.7 257.4 218.4 241.7 116.7 125.1 251.3 99.3 55.4 246.9 132.2 143.7 480.4 162.0 159.1 273.5 282.8 63.7 226.9 153.3 196.7 55.8 87.9 189.0 288.7 127.5 492.0 384.8 250.5 128.7 97.4 188.9 118.3 286.8 242.1 272.3 296.8 489.5 443.4 316.0 469.1 185.4 329.4 459.4 SRSF3 "SFRS3, SRp20" ENSG00000112081 "Serine and arginine rich splicing factor 3" P84103 6 36594353-36605600 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012986, HPA056981" Supported Supported Nucleoplasm NA NA 1600000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB012986: AB_2533150, HPA056981: AB_2683299" "unprognostic (3.25e-1)" "unprognostic (1.08e-3)" "prognostic favorable (2.56e-4)" "unprognostic (8.19e-2)" "unprognostic (2.06e-2)" "unprognostic (2.77e-2)" "prognostic unfavorable (6.22e-5)" "unprognostic (2.92e-2)" "prognostic unfavorable (1.95e-4)" "prognostic favorable (1.37e-4)" "unprognostic (9.61e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (9.88e-2)" "unprognostic (3.33e-2)" "unprognostic (8.33e-2)" "unprognostic (1.06e-2)" 97.2 62.5 39.2 93.5 40.9 172.3 90.2 43.6 44.0 72.6 42.4 89.6 54.0 76.1 62.5 97.8 78.0 40.5 70.2 40.1 43.8 83.3 75.3 68.8 118.9 40.0 40.6 84.0 58.0 62.3 49.2 74.6 41.6 58.6 95.2 45.2 57.8 64.6 76.0 66.4 73.2 89.9 43.1 67.2 74.9 59.9 44.0 164.3 60.7 48.5 147.9 97.7 72.0 45.5 357.2 232.3 401.4 308.9 151.9 117.9 247.2 248.4 206.5 408.6 312.2 275.1 248.2 593.4 174.3 273.3 266.8 275.1 533.1 395.4 433.2 279.3 327.3 357.0 175.5 312.3 184.9 485.2 289.6 105.8 131.6 267.4 295.6 130.3 315.2 354.4 438.7 244.1 300.8 277.4 601.0 457.0 424.5 414.5 241.5 527.3 384.2 355.9 292.2 291.1 308.7 291.8 276.1 267.4 385.4 284.9 271.2 513.1 207.9 208.1 303.9 211.0 380.1 238.6 381.4 822.9 178.4 443.7 295.5 85.6 179.0 57.9 145.8 176.6 166.0 129.0 136.8 154.7 350.7 113.5 136.1 140.8 17.1 190.5 125.1 206.8 184.2 305.6 39.2 40.9 43.6 44.0 40.1 43.8 40.0 40.6 41.6 43.1 44.0 45.5 648.3 201.9 238.6 47.3 337.6 469.6 425.1 308.4 225.9 146.2 371.3 388.4 227.9 198.8 258.0 125.0 54.2 495.6 574.3 245.3 363.9 357.3 176.1 216.0 295.7 346.9 332.9 345.9 24.0 324.9 816.9 373.6 226.8 251.1 396.8 275.2 243.8 182.7 359.3 99.3 23.8 409.9 191.2 262.9 559.3 321.2 211.9 356.5 334.4 45.9 366.3 368.8 334.8 38.2 51.1 290.1 301.9 172.3 256.3 401.7 259.2 274.7 164.8 154.5 203.8 497.3 448.2 374.2 290.8 312.2 445.8 526.1 415.2 184.1 427.4 285.1 SS18 "SSXT, SYT" ENSG00000141380 "SS18 subunit of BAF chromatin remodeling complex" Q15532 18 26016253-26091217 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055741, HPA059539" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "HPA055741: AB_2682901, HPA059539: AB_2684055" "unprognostic (2.03e-2)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.95e-2)" "unprognostic (3.39e-1)" "unprognostic (8.74e-2)" "unprognostic (4.59e-2)" "unprognostic (1.53e-2)" "unprognostic (1.63e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (2.47e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (1.40e-2)" "unprognostic (1.30e-1)" 29.5 46.2 21.2 27.7 24.9 23.0 33.2 23.6 22.6 32.1 26.3 28.4 18.0 32.2 39.4 34.5 33.2 29.8 29.4 21.8 23.6 36.8 41.9 26.8 35.9 25.5 24.7 47.7 23.8 52.0 30.5 36.9 24.5 35.0 23.4 24.7 29.7 31.2 11.6 41.2 27.7 31.8 23.8 28.5 26.8 25.9 22.4 33.6 45.4 17.5 38.6 38.3 31.2 29.1 52.4 37.2 90.8 43.9 69.0 65.1 45.8 62.9 57.6 55.1 53.6 24.5 43.1 90.6 49.1 75.0 49.0 67.1 50.1 62.0 67.5 58.4 23.3 45.4 56.2 39.8 55.6 69.8 66.5 81.4 71.3 68.6 74.3 53.7 43.7 26.6 34.2 45.0 76.3 53.1 28.5 39.9 17.3 51.6 35.7 33.0 70.2 44.2 57.6 60.7 38.1 57.7 96.0 43.8 27.0 64.6 45.5 40.9 51.4 114.1 22.6 26.8 63.9 80.9 58.3 64.0 53.9 47.8 62.2 27.1 13.5 19.4 16.4 19.7 19.2 17.7 15.6 17.1 15.2 15.0 16.2 18.6 5.7 24.6 20.2 8.5 18.2 16.3 21.2 24.9 23.6 22.6 21.8 23.6 25.5 24.7 24.5 23.8 22.4 29.1 28.8 28.9 23.7 43.8 45.9 8.9 27.8 13.9 40.9 28.8 29.4 26.4 16.0 22.8 18.1 23.9 16.7 70.0 34.0 25.2 21.5 30.3 52.7 44.8 31.5 27.9 24.7 26.1 50.7 26.0 48.8 30.4 22.4 32.3 36.8 60.2 22.1 34.5 27.6 87.5 42.7 25.7 6.1 25.5 10.9 51.4 33.2 22.6 5.4 65.6 19.7 51.1 22.6 90.5 118.0 34.8 15.7 41.0 42.0 24.8 19.1 24.9 30.5 29.8 39.5 23.4 31.3 29.3 20.3 37.2 13.2 85.1 34.0 30.7 16.9 24.7 SS18L1 "CREST, KIAA0693" ENSG00000184402 "SS18L1 subunit of BAF chromatin remodeling complex" O75177 20 62143769-62182514 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011827, HPA059046" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "CAB011827: AB_778216, HPA059046: AB_2683888" "unprognostic (4.12e-2)" "unprognostic (5.82e-2)" "unprognostic (1.54e-1)" "unprognostic (3.03e-2)" "unprognostic (6.57e-2)" "prognostic favorable (8.00e-5)" "unprognostic (1.39e-1)" "prognostic favorable (3.74e-4)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" "unprognostic (2.47e-3)" "unprognostic (6.43e-2)" "unprognostic (2.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (9.94e-3)" 7.7 8.8 11.3 6.6 10.1 6.6 7.8 26.1 13.9 10.3 7.5 8.2 7.7 8.0 8.4 10.9 9.2 5.0 8.3 9.7 9.7 10.5 37.8 9.7 6.4 12.2 9.5 10.6 12.1 6.4 11.9 7.1 11.6 9.0 6.1 10.7 8.5 5.4 13.3 19.8 8.4 5.6 6.7 10.1 9.2 8.9 11.1 6.5 9.1 9.4 5.8 8.5 10.1 18.9 11.1 12.5 17.7 16.3 7.6 8.8 12.9 10.3 3.9 16.6 8.0 44.1 10.2 6.6 13.3 5.8 8.6 27.9 10.5 9.8 15.2 4.5 6.9 29.6 30.9 23.5 5.7 11.2 25.6 5.5 20.5 8.4 7.0 9.7 7.5 11.3 20.3 12.8 9.6 13.2 16.7 17.2 7.3 11.0 13.7 18.5 23.1 7.8 12.5 13.9 33.4 18.6 17.7 22.4 15.6 11.3 20.8 17.6 9.3 31.8 19.0 12.0 14.6 13.8 13.2 5.6 15.9 10.6 10.9 0.0 0.4 0.1 0.3 0.3 0.2 0.1 0.2 0.3 0.3 1.2 0.6 0.2 0.6 0.4 0.7 0.2 0.2 0.1 11.3 10.1 26.1 13.9 9.7 9.7 12.2 9.5 11.6 6.7 11.1 18.9 9.7 9.6 7.0 19.6 5.2 16.4 4.8 8.9 17.1 17.9 10.8 8.8 10.3 2.8 11.4 7.3 22.9 5.6 6.7 7.1 3.9 5.0 10.8 11.9 8.1 9.7 14.3 4.8 29.5 2.7 3.3 8.9 7.7 12.8 1.3 10.8 8.6 40.4 4.8 15.2 32.8 6.6 14.2 10.4 12.7 20.8 7.5 7.4 12.4 20.6 10.0 4.4 4.1 8.5 25.5 8.2 7.3 3.4 7.4 9.5 8.3 9.1 9.0 16.5 6.6 11.1 7.7 4.6 10.2 10.6 17.5 7.7 6.0 10.6 7.1 6.9 SST SMST ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 449.5;intestine: 386.6;pancreas: 479.4;stomach 1: 418.0" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 1404.1;Intestinal goblet cells: 460.2" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 449.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 22.4;U-2 OS: 44.7;U-251 MG: 7.6;U-698: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" 5.5 43.0 59.9 4.6 52.1 4.2 0.5 1.3 67.8 0.6 2.5 31.8 386.6 0.7 0.1 1.6 0.4 1.1 1.3 30.6 449.5 6.2 0.3 0.3 1.5 96.9 48.1 2.4 479.4 0.0 9.3 0.1 50.3 1.3 23.8 6.3 0.1 21.6 0.1 8.9 133.3 2.8 137.8 0.2 418.0 0.2 117.2 1.1 1.0 0.0 0.0 7.3 1.8 18.7 0.0 0.0 0.8 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 44.7 0.4 7.6 0.0 2.9 11.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.9 52.1 1.3 67.8 30.6 449.5 96.9 48.1 50.3 137.8 117.2 18.7 0.0 0.0 0.0 9.1 0.5 0.0 0.0 3.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 5.5 0.0 0.1 0.0 4.3 0.0 0.0 0.3 0.3 0.5 0.1 1404.1 0.0 1.7 0.0 0.2 0.7 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 146.2 460.2 215.7 0.0 0.0 0.1 0.0 0.0 0.0 9.4 3.6 0.0 0.0 3.0 9.1 0.0 0.6 0.0 0.0 0.0 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.9 13.8 0.2 SSX1 CT5.1 ENSG00000126752 "SSX family member 1" Q16384 X 48255392-48267444 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 6.8" "Group enriched" "Detected in some" 4 "Spermatocytes: 24.2;Spermatogonia: 30.2" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Daudi: 66.1;Karpas-707: 90.5;U-2197: 22.7" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " "unprognostic (2.25e-1)" "unprognostic (3.51e-3)" "unprognostic (2.36e-1)" "unprognostic (4.32e-3)" "unprognostic (3.38e-1)" "unprognostic (5.41e-2)" "unprognostic (6.94e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 90.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 22.7 0.1 0.0 4.8 0.1 5.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 24.2 30.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSX2 "CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX" ENSG00000241476 "SSX family member 2" Q16385 X 52696896-52707189 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 15.0" "Cell type enriched" "Detected in single" 4 "Spermatogonia: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSX2B CT5.2b ENSG00000268447 "SSX family member 2B" Q16385 X 52751132-52790305 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 29.9" "Cell type enriched" "Detected in single" 9 "Spermatogonia: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.7;PC-3: 2.5;T-47d: 1.0;U-2197: 1.5" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 29.9 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.5 0.0 0.2 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.4 0.2 0.7 0.9 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSX4 CT5.4 ENSG00000268009 "SSX family member 4" O60224 X 48383516-48393347 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 2.2;Karpas-707: 5.4;U-266/70: 4.5;U-266/84: 3.3" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Nucleoplasm, Nucleoli" "HPA045683: AB_2679418, HPA071685: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.4 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 489.4;Paneth cells: 327.2;Proximal enterocytes: 251.9;Undifferentiated cells: 216.9;Urothelial cells: 286.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.0" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.0" "Cell line enhanced" "Detected in many" "CACO-2: 224.2;CAPAN-2: 443.0;HaCaT: 311.4;OE19: 240.4;RPMI-8226: 301.2;SK-BR-3: 203.1;T-47d: 308.3;U-698: 218.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 4.3 3.9 0.8 26.7 1.2 4.3 17.7 1.8 2.9 18.6 1.2 124.7 130.7 5.7 21.8 104.5 37.1 32.6 0.9 0.9 1.1 43.2 6.3 18.5 11.9 1.8 1.7 0.6 59.2 36.5 19.1 15.1 3.1 23.1 60.1 0.0 58.7 23.6 0.3 50.2 144.8 5.4 1.1 9.1 64.9 1.0 10.0 10.5 28.6 0.0 20.9 34.8 42.5 2.7 167.2 0.2 0.0 0.6 0.0 0.0 86.4 0.0 0.0 0.0 0.0 224.2 443.0 163.6 16.7 0.0 0.1 311.4 0.0 99.3 0.0 0.1 0.2 0.1 0.1 0.9 0.0 22.0 0.8 0.0 49.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 128.5 0.3 1.1 1.7 240.4 0.9 0.2 0.0 301.2 28.8 134.2 17.8 0.4 1.5 203.1 0.4 1.6 308.3 32.0 0.1 0.4 2.7 0.7 0.7 0.2 0.3 218.5 0.3 50.4 0.5 0.0 3.6 3.4 0.0 2.2 0.1 5.0 0.0 0.0 6.2 3.6 0.0 0.0 0.5 0.0 0.3 25.0 0.0 1.2 0.8 1.2 1.8 2.9 0.9 1.1 1.8 1.7 3.1 1.1 10.0 2.7 0.2 32.1 28.6 0.0 18.2 40.9 51.5 45.2 26.2 0.0 36.5 21.5 1.2 77.2 61.6 62.5 0.0 45.6 26.1 489.4 3.9 115.8 37.8 43.9 5.7 1.7 123.4 0.8 1.0 91.8 14.6 3.2 112.1 79.6 11.4 0.2 0.4 2.1 58.1 0.0 0.4 201.0 148.5 22.7 13.2 13.9 1.8 28.0 7.2 0.0 13.6 0.0 1.0 0.0 0.1 153.4 327.2 0.7 5.9 108.7 251.9 10.0 76.4 0.0 6.6 0.0 4.9 0.2 0.3 61.3 43.9 39.7 2.9 0.0 216.9 286.8 STAG2 "SA-2, SA2, SCC3B" ENSG00000101972 "Stromal antigen 2" Q8N3U4 X 123960212-124422664 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002857 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA002857: AB_1079861" "unprognostic (1.62e-1)" "unprognostic (1.01e-2)" "unprognostic (6.75e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-2)" "unprognostic (2.70e-2)" "unprognostic (3.77e-2)" "unprognostic (9.67e-3)" "unprognostic (4.68e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-1)" "unprognostic (3.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.81e-1)" "unprognostic (2.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.97e-1)" 27.9 22.9 20.7 34.2 26.3 72.8 41.5 32.6 24.1 33.3 30.4 28.8 23.8 35.7 28.3 26.8 30.1 25.2 21.5 18.0 22.6 33.7 28.5 28.6 45.0 26.2 21.9 46.0 31.7 51.9 12.0 35.8 27.8 29.8 28.2 45.5 26.5 29.6 23.3 26.1 26.5 25.8 24.2 37.4 28.5 8.0 21.2 81.4 49.3 36.0 44.3 28.4 17.6 39.6 62.6 56.9 84.5 53.0 34.9 52.3 54.4 58.0 61.8 58.5 73.2 53.8 65.1 115.0 79.6 52.3 65.5 55.6 173.6 48.8 82.5 81.9 74.7 106.6 110.8 35.7 35.6 140.7 80.0 42.2 46.4 69.5 111.4 50.2 49.7 114.2 105.4 118.9 43.1 67.8 180.6 62.9 44.5 55.8 84.4 125.9 112.0 96.1 44.9 117.3 75.7 60.6 131.2 47.7 66.9 59.2 28.9 62.2 61.5 0.3 31.1 69.4 66.6 50.9 82.2 141.6 36.8 84.3 60.3 28.2 15.2 28.0 15.0 18.9 17.8 15.0 15.6 14.6 19.1 19.0 21.3 17.5 44.5 18.8 23.1 16.5 13.5 10.0 20.7 26.3 32.6 24.1 18.0 22.6 26.2 21.9 27.8 24.2 21.2 39.6 71.1 64.1 56.6 42.4 80.9 56.2 61.5 31.5 72.3 51.0 58.0 48.4 44.9 37.1 50.6 44.1 60.5 32.2 113.4 42.9 21.5 42.3 1.1 65.1 70.4 62.3 58.1 77.0 41.8 38.2 32.7 64.5 39.8 79.3 58.1 53.6 59.3 42.2 36.0 45.4 51.9 35.0 28.5 71.4 65.0 4.2 65.9 89.9 33.8 70.3 91.4 61.2 97.9 69.4 114.0 54.9 29.3 69.2 73.8 81.4 28.0 35.7 51.4 62.9 65.7 104.0 60.3 14.8 15.4 51.0 56.1 71.4 87.2 49.5 38.9 83.6 STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 260.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-2)" "unprognostic (8.92e-3)" "unprognostic (2.09e-2)" "unprognostic (2.94e-1)" "prognostic unfavorable (3.60e-5)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (6.25e-3)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (1.33e-1)" "unprognostic (5.22e-2)" "unprognostic (8.51e-3)" "unprognostic (3.00e-2)" 24.8 33.4 18.3 18.8 29.1 25.4 23.4 21.6 18.9 22.3 14.9 21.5 24.1 20.4 2.7 24.1 21.5 17.2 16.3 17.9 15.4 18.9 25.8 28.8 22.3 21.1 21.3 21.3 26.5 15.2 24.0 17.1 19.0 20.1 5.2 3.2 21.2 11.3 23.9 27.0 26.7 9.2 18.7 33.1 26.5 26.2 22.5 14.8 21.4 9.5 8.8 21.0 20.1 18.5 29.3 47.6 18.6 33.5 19.9 22.9 31.2 23.1 24.9 27.1 24.3 24.0 47.6 25.2 47.7 17.8 30.8 55.4 11.3 21.0 6.3 36.2 34.5 15.2 18.8 30.1 25.9 29.6 35.5 24.5 19.0 29.8 12.6 19.0 23.4 36.4 41.0 27.4 23.5 24.7 32.2 25.6 22.2 15.3 20.6 28.5 31.4 40.1 15.0 35.7 24.9 29.1 16.1 260.8 64.0 10.8 34.1 41.7 26.3 43.2 29.5 46.5 43.6 27.5 37.8 18.7 36.2 36.8 45.1 23.7 36.3 54.4 42.7 35.5 30.7 20.8 29.6 32.7 38.3 26.1 29.1 27.8 63.6 39.6 29.3 18.7 38.5 33.8 18.3 29.1 21.6 18.9 17.9 15.4 21.1 21.3 19.0 18.7 22.5 18.5 45.8 3.2 7.5 31.0 23.2 16.6 13.0 23.4 14.2 12.6 19.9 14.6 3.4 18.6 14.8 11.0 37.5 28.5 32.9 21.0 9.8 26.5 2.7 9.7 11.7 35.8 27.5 11.1 17.3 35.4 37.2 16.2 29.6 11.0 19.0 22.2 45.0 11.9 49.8 18.5 14.8 11.6 14.2 49.0 18.5 5.3 17.1 27.7 5.4 9.4 18.5 15.8 29.9 12.1 30.2 35.9 22.9 13.2 24.3 20.2 41.5 10.3 8.3 13.2 13.1 21.8 14.4 9.3 16.2 15.9 16.9 40.0 35.2 18.6 15.1 20.1 STAT3 APRF ENSG00000168610 "Signal transducer and activator of transcription 3" P40763 17 42313324-42388540 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Diabetes mellitus, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001671, CAB003859, HPA058603, CAB068241, CAB068242" Supported Supported Nucleoplasm,Cytosol NA NA 55000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "CAB003859: AB_347629, CAB068241: AB_2665663, CAB068242: AB_2665662, HPA001671: AB_1080102, HPA058603: AB_2683772" "unprognostic (1.83e-2)" "unprognostic (2.42e-1)" "unprognostic (9.23e-3)" "unprognostic (2.91e-1)" "unprognostic (5.59e-3)" "unprognostic (1.78e-2)" "unprognostic (8.26e-2)" "unprognostic (1.51e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-1)" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (6.47e-3)" "unprognostic (7.75e-3)" "unprognostic (2.21e-2)" "unprognostic (7.63e-2)" "unprognostic (1.61e-1)" 105.6 68.1 32.4 78.5 34.5 63.2 84.4 38.7 30.2 62.6 32.4 76.9 45.9 71.6 28.2 81.6 74.0 71.7 101.2 28.6 44.6 77.2 143.1 106.0 55.3 48.4 40.7 65.4 67.3 35.3 53.3 55.6 43.4 62.9 46.5 29.9 63.5 48.2 123.9 66.8 68.1 72.1 43.9 68.0 62.3 24.6 43.0 50.5 61.9 92.1 65.2 88.6 64.3 43.1 61.5 116.0 47.4 48.2 103.7 97.6 35.4 66.5 89.7 59.6 58.3 30.3 55.8 18.5 68.2 71.2 90.3 89.2 45.8 72.6 47.7 160.6 31.4 131.2 60.4 62.4 77.3 31.8 79.0 152.1 69.8 47.4 68.9 62.2 81.1 33.4 80.1 56.4 40.1 43.8 118.7 31.3 28.5 63.4 0.0 26.6 133.8 28.1 91.3 77.2 45.2 29.8 81.4 184.9 29.2 57.2 100.5 49.1 68.7 88.9 44.9 54.8 56.5 82.9 75.3 16.4 56.1 32.8 41.6 121.1 78.4 100.0 79.5 79.9 64.4 40.2 57.5 62.6 54.3 36.6 58.7 56.5 262.6 58.3 80.8 29.3 47.9 124.5 32.4 34.5 38.7 30.2 28.6 44.6 48.4 40.7 43.4 43.9 43.0 43.1 216.0 93.0 173.7 46.0 111.6 129.5 105.3 76.8 138.3 92.6 147.1 113.0 59.7 54.3 103.2 134.3 281.5 25.2 115.1 148.9 17.6 83.2 33.5 129.3 187.0 164.7 124.0 54.3 24.2 96.8 38.2 154.0 109.1 153.9 142.0 86.3 115.3 115.7 69.1 25.2 35.8 97.8 69.2 71.0 121.7 13.7 71.7 111.7 72.9 51.5 94.1 131.3 78.2 30.7 41.7 82.9 94.5 60.9 104.6 147.9 206.4 46.3 88.5 406.7 65.7 189.5 169.7 31.5 15.3 93.4 160.1 31.2 170.2 102.3 117.5 90.6 STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;testis: 29.2" "Cell type enhanced" "Detected in many" "dendritic cells: 139.0;Early spermatids: 275.1;Excitatory neurons: 85.9;Late spermatids: 66.0;NK-cells: 108.1;Plasma cells: 83.8;T-cells: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.6;T-cells: 121.2" "Cell line enhanced" "Detected in some" "Karpas-707: 58.8;U-266/70: 32.9;U-266/84: 12.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA001860, CAB013108" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB013108: , HPA001860: AB_1080104" "unprognostic (3.90e-5)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (6.45e-4)" "unprognostic (3.77e-2)" "unprognostic (4.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (2.65e-1)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" 4.7 4.0 3.4 11.5 4.4 15.7 3.0 0.1 10.4 1.6 0.1 2.8 4.5 1.9 2.6 1.4 1.6 5.1 23.0 3.8 3.6 4.5 9.5 7.8 18.0 2.1 1.7 1.5 2.2 1.2 15.0 2.6 2.0 1.8 3.4 2.1 2.2 1.3 1.2 1.1 6.9 1.4 0.6 15.5 4.4 29.2 3.4 9.0 2.4 1.0 10.4 5.9 1.8 4.5 0.1 1.7 1.1 0.0 0.0 3.6 0.3 0.6 2.2 0.6 2.2 0.4 0.8 0.0 0.2 2.8 1.6 0.9 0.0 4.7 1.2 0.0 0.8 1.3 0.0 0.0 0.6 0.0 0.1 1.5 2.3 1.1 0.5 0.1 0.0 6.0 0.0 58.8 0.2 0.0 3.5 0.0 0.3 0.0 0.9 0.0 0.0 4.3 0.2 0.1 0.1 1.2 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.1 1.6 0.0 32.9 12.8 0.0 1.2 0.0 0.1 15.7 0.4 0.1 121.2 0.8 107.3 1.8 71.6 101.2 0.6 1.0 68.1 95.8 2.8 76.6 0.8 9.3 28.1 55.3 3.4 4.4 0.1 10.4 3.8 3.6 2.1 1.7 2.0 0.6 3.4 4.5 2.9 3.2 4.2 2.6 14.5 1.3 0.6 2.9 0.0 0.9 0.9 1.1 20.3 4.3 0.6 1.8 8.4 0.4 139.0 0.5 0.0 0.6 275.1 1.1 0.5 1.2 0.0 10.5 85.9 0.2 2.9 2.9 8.6 0.7 1.3 0.8 1.1 1.1 1.1 0.0 59.4 0.3 0.0 6.3 10.6 66.0 0.3 14.4 5.4 7.5 6.3 0.0 108.1 6.0 2.4 0.1 0.3 0.4 83.8 1.0 0.0 0.8 2.4 0.2 0.0 0.6 3.7 8.3 1.2 0.4 1.7 0.5 137.4 0.1 0.3 0.7 STAT5A "MGF, STAT5" ENSG00000126561 "Signal transducer and activator of transcription 5A" P42229 17 42287547-42311943 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Lactation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 78.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 101.0;HEL: 153.5;HMC-1: 85.2;K-562: 262.4;MOLT-4: 163.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003860, HPA027873, HPA042128, HPA049883, HPA051156" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Cytosol" "CAB003860: AB_562347, HPA027873: AB_10603893, HPA042128: AB_2677864, HPA049883: AB_2680931, HPA051156: AB_2681366" "prognostic favorable (5.87e-4)" "unprognostic (3.09e-3)" "unprognostic (2.31e-2)" "unprognostic (1.76e-1)" "unprognostic (1.43e-1)" "unprognostic (3.41e-3)" "unprognostic (2.15e-1)" "unprognostic (6.22e-2)" "unprognostic (3.33e-1)" "unprognostic (6.82e-3)" "unprognostic (2.76e-1)" "unprognostic (2.11e-1)" "unprognostic (3.85e-2)" "unprognostic (5.74e-2)" "unprognostic (1.90e-2)" "unprognostic (1.98e-1)" "unprognostic (5.49e-3)" 78.9 40.6 4.3 28.9 5.7 52.1 48.8 5.3 4.8 19.1 5.4 24.0 8.6 17.8 5.7 9.9 19.0 13.9 13.9 3.6 7.5 13.9 8.1 23.3 37.5 8.0 7.6 22.5 12.2 2.4 10.5 7.3 7.4 15.4 9.1 1.2 15.7 13.7 23.8 18.4 22.4 14.3 6.7 29.8 14.0 4.9 7.7 24.4 13.3 13.8 27.1 24.1 15.4 8.6 3.9 4.9 0.5 0.0 35.7 17.5 0.4 2.1 8.6 4.0 2.3 0.0 3.7 0.3 9.0 8.5 0.2 0.3 0.8 0.3 1.1 101.0 0.0 153.5 9.3 1.3 15.5 13.5 85.2 36.8 2.1 1.7 2.0 0.0 12.3 2.0 262.4 0.1 2.3 0.1 163.5 64.7 1.4 2.5 0.0 4.5 1.1 13.8 1.1 2.6 0.3 0.0 10.0 3.9 17.8 0.9 2.5 13.9 7.2 8.0 2.6 3.9 0.1 0.2 0.1 0.0 1.0 25.4 2.5 9.8 15.1 7.9 10.3 18.6 14.4 8.2 18.3 15.2 18.7 6.6 18.0 15.0 18.3 17.4 24.9 6.6 14.5 12.9 4.3 5.7 5.3 4.8 3.6 7.5 8.0 7.6 7.4 6.7 7.7 8.6 14.0 0.0 10.6 2.6 18.7 7.4 3.8 4.5 5.7 2.9 35.8 24.5 29.6 5.7 3.4 5.5 0.0 1.2 17.7 5.5 5.9 5.0 0.4 7.2 5.2 21.2 0.0 33.2 0.2 13.6 2.9 15.3 5.1 11.9 22.8 6.8 6.1 3.3 21.4 0.0 1.3 4.2 0.0 24.5 41.3 3.5 32.6 31.8 8.8 5.6 41.0 3.9 8.2 2.5 5.0 9.6 8.1 41.0 12.5 12.2 1.8 14.4 8.4 0.7 6.6 13.7 10.2 0.0 0.9 4.4 7.7 1.4 29.2 7.7 6.5 7.0 STAT5B ENSG00000173757 "Signal transducer and activator of transcription 5B" P51692 17 42199177-42276707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 100.5;Late spermatids: 188.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 121.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004298, CAB005418, HPA042128, HPA049883, HPA051156" Approved Approved Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "CAB004298: AB_2197067, CAB005418: AB_632445, HPA042128: AB_2677864, HPA049883: AB_2680931, HPA051156: AB_2681366" "unprognostic (1.49e-1)" "unprognostic (3.60e-2)" "unprognostic (4.06e-2)" "prognostic favorable (9.37e-4)" "unprognostic (2.68e-1)" "unprognostic (4.29e-1)" "unprognostic (2.23e-1)" "unprognostic (1.03e-1)" "unprognostic (3.06e-2)" "unprognostic (7.98e-2)" "prognostic favorable (1.63e-4)" "unprognostic (1.36e-1)" "prognostic favorable (2.39e-5)" "unprognostic (9.19e-2)" "unprognostic (2.95e-1)" "unprognostic (1.54e-1)" "unprognostic (2.13e-1)" 45.9 45.7 26.4 35.1 26.5 42.4 36.7 33.4 29.0 43.6 24.6 45.3 14.8 59.1 19.3 19.2 50.8 23.6 24.5 23.5 42.9 24.3 24.4 32.5 43.6 32.8 33.9 55.9 22.8 21.1 40.8 31.5 32.9 29.2 17.0 18.7 22.8 34.2 73.3 25.3 30.7 42.7 27.4 42.3 27.6 23.5 49.9 37.6 22.7 46.5 34.7 43.4 31.5 26.1 15.0 22.9 33.3 9.0 40.6 20.4 15.9 15.0 26.5 21.0 18.2 10.1 12.3 48.1 21.8 17.2 41.3 18.7 19.9 13.0 16.6 121.8 23.0 47.1 44.5 15.6 22.3 20.9 72.7 25.1 19.6 15.9 19.9 18.0 33.6 31.9 86.5 10.1 8.8 14.6 99.2 54.9 8.3 34.3 0.2 42.0 20.9 16.8 13.3 23.5 24.5 14.4 27.3 34.4 21.2 7.4 24.3 24.3 26.0 29.2 10.2 15.2 21.2 19.8 9.8 23.9 11.6 21.7 15.5 11.5 3.3 5.9 6.6 3.0 7.1 2.9 9.3 7.6 2.9 2.9 6.5 5.5 22.5 4.2 3.7 2.1 8.4 4.7 26.4 26.5 33.4 29.0 23.5 42.9 32.8 33.9 32.9 27.4 49.9 26.1 30.2 6.4 19.5 41.8 12.9 8.9 5.7 4.5 2.8 21.2 25.1 22.7 20.7 5.7 7.8 3.7 20.9 8.0 31.2 8.4 5.9 8.2 100.5 10.1 22.4 26.0 10.2 12.4 23.7 11.8 6.1 18.8 13.3 15.0 16.4 16.1 20.0 11.2 9.4 10.1 61.2 6.1 8.2 13.3 17.1 188.5 47.2 16.9 10.6 51.5 23.7 9.5 26.8 69.4 60.8 12.2 6.2 74.4 13.6 11.9 7.9 9.8 6.3 13.3 39.5 20.0 23.0 4.3 7.3 5.9 9.8 12.7 34.4 15.5 7.5 7.7 STAT6 "D12S1644, IL-4-STAT" ENSG00000166888 "Signal transducer and activator of transcription 6" P42226 12 57095408-57132139 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001861 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol Nucleoplasm "HPA001861: AB_1080106" "unprognostic (3.43e-3)" "unprognostic (1.87e-1)" "unprognostic (1.37e-1)" "prognostic favorable (1.69e-4)" "unprognostic (4.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.22e-1)" "unprognostic (6.70e-2)" "unprognostic (1.88e-2)" "unprognostic (3.65e-1)" "unprognostic (5.39e-2)" "unprognostic (1.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.55e-1)" "prognostic favorable (7.76e-4)" "prognostic favorable (1.14e-4)" 76.0 84.0 22.5 68.1 24.2 40.1 67.6 19.0 25.4 85.4 29.7 91.3 79.0 81.9 49.0 93.3 82.4 66.2 50.2 22.3 21.3 68.8 75.2 83.4 78.3 22.6 20.6 93.3 48.8 52.9 18.9 45.0 22.2 81.5 71.1 3.5 70.1 68.6 14.3 108.2 99.0 80.5 21.4 111.3 78.5 15.0 24.4 81.7 57.5 20.5 91.9 96.8 81.7 22.8 60.2 55.2 13.8 24.3 153.2 138.4 39.7 53.5 103.3 49.5 37.7 26.8 78.8 145.8 78.1 106.4 0.2 82.0 18.7 89.2 38.1 70.5 4.4 32.0 57.5 32.8 93.0 39.0 97.5 213.5 75.1 67.3 55.9 145.4 91.8 45.7 23.3 19.2 69.5 21.3 44.9 41.5 20.3 81.1 12.6 50.4 1.3 49.6 95.6 92.9 0.3 1.2 46.7 35.3 45.6 19.1 53.4 90.8 68.2 0.6 30.7 51.9 0.4 0.1 1.0 35.4 48.6 39.2 67.3 12.6 19.6 11.1 6.9 19.1 6.9 8.0 6.3 6.2 14.1 6.4 5.4 5.7 34.4 6.0 15.0 6.3 6.7 26.8 22.5 24.2 19.0 25.4 22.3 21.3 22.6 20.6 22.2 21.4 24.4 22.8 27.6 48.1 60.8 5.5 45.1 29.8 44.3 33.4 31.3 1.8 23.8 21.2 15.1 27.1 43.3 49.7 0.0 2.0 38.4 80.4 15.6 38.2 8.0 35.8 33.1 32.0 33.0 26.3 13.1 36.1 10.2 36.9 80.0 51.9 58.2 27.6 38.9 41.0 36.4 0.0 1.3 40.3 24.4 73.2 51.7 17.9 59.4 54.5 21.4 26.2 66.9 3.4 42.2 0.5 1.1 45.1 63.4 50.8 10.6 49.2 80.0 27.9 53.1 1.0 26.3 20.9 31.7 1.0 1.4 37.1 32.8 6.3 31.2 29.2 42.9 62.0 STEAP1 "PRSS24, STEAP" ENSG00000164647 "STEAP family member 1" Q9UHE8 7 90154456-90164829 "Cancer-related genes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 83.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 140.5;Club cells: 72.6;Prostatic glandular cells: 85.1;Theca cells: 64.4;Urothelial cells: 54.0" "Cancer enriched" "Detected in all" 6 "prostate cancer: 94.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.1;CAPAN-2: 135.2;U-138 MG: 169.2" "Low region specificity" "Detected in many" HPA030985 Uncertain NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA030985: AB_2673686" "unprognostic (2.88e-3)" "unprognostic (2.29e-1)" "unprognostic (1.19e-1)" "unprognostic (3.21e-3)" "unprognostic (9.20e-3)" "unprognostic (2.03e-1)" "unprognostic (1.33e-2)" "unprognostic (6.74e-3)" "unprognostic (6.36e-2)" "unprognostic (6.45e-3)" "unprognostic (8.31e-3)" "unprognostic (3.79e-1)" "unprognostic (2.60e-2)" "unprognostic (4.39e-2)" "unprognostic (2.42e-1)" "unprognostic (6.09e-2)" "unprognostic (1.38e-1)" 32.9 2.2 1.0 32.9 1.4 0.0 18.5 0.8 2.3 9.6 1.4 18.1 5.2 4.2 0.8 12.6 10.7 16.4 7.2 1.3 1.0 6.6 27.6 14.2 0.3 1.3 0.8 6.0 6.0 0.3 3.7 0.7 1.0 83.8 13.7 0.7 15.1 2.1 1.3 4.6 7.8 26.9 0.8 2.5 13.9 4.2 1.0 0.9 5.0 2.5 4.6 34.5 5.8 1.1 26.9 52.5 3.3 9.8 105.1 89.5 0.9 17.8 20.5 2.4 2.7 38.8 135.2 0.3 0.9 28.9 43.5 5.3 22.0 22.6 5.1 0.0 7.6 0.1 0.5 13.0 4.3 0.0 0.1 59.7 3.7 68.0 37.4 16.6 92.6 7.3 1.2 74.0 29.6 0.4 0.0 0.9 15.7 1.3 23.2 0.1 0.0 0.3 20.8 5.5 0.0 1.2 6.4 0.2 12.1 1.9 29.4 0.4 50.8 169.2 8.0 83.9 22.8 14.0 0.5 0.1 83.4 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.8 2.3 1.3 1.0 1.3 0.8 1.0 0.8 1.0 1.1 1.8 0.0 0.5 2.3 0.3 4.2 41.9 140.5 7.4 0.1 12.8 11.4 0.8 5.7 72.6 1.8 0.0 0.0 0.6 7.0 0.0 3.4 0.4 1.3 4.9 4.5 7.2 0.0 5.3 38.6 0.1 25.2 10.7 4.6 0.0 10.5 1.8 33.1 0.5 0.0 1.7 4.3 24.4 0.8 5.4 1.1 0.9 1.3 7.2 0.0 0.0 10.5 0.0 1.5 1.3 44.4 20.5 1.5 1.3 85.1 2.5 14.7 13.1 0.3 6.6 6.0 26.9 17.1 36.9 12.2 2.3 0.3 0.4 64.4 16.6 54.0 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 154.9;Late spermatids: 338.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "CAB016231: AB_627890, CAB022105: , HPA017254: AB_1852924, HPA067481: AB_2685847" "unprognostic (8.60e-2)" "unprognostic (1.68e-1)" "unprognostic (5.00e-2)" "prognostic favorable (3.69e-5)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (9.11e-3)" "unprognostic (3.19e-1)" "unprognostic (9.08e-2)" "unprognostic (1.26e-1)" "unprognostic (1.95e-3)" "unprognostic (7.70e-3)" "unprognostic (3.54e-2)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.12e-3)" 32.1 44.2 18.8 18.2 15.5 34.1 32.3 24.8 23.5 35.4 24.7 38.7 25.6 33.6 5.5 39.7 34.9 11.8 48.4 18.3 14.7 36.4 45.5 30.5 20.5 19.2 19.4 37.9 34.2 16.1 36.8 12.6 15.2 39.3 7.7 5.7 29.7 16.1 108.2 40.2 37.7 9.6 16.3 48.3 38.1 102.4 17.6 15.0 34.3 27.7 12.9 34.4 35.0 14.9 50.0 25.8 19.9 35.9 18.6 17.0 35.5 24.0 27.7 25.1 25.4 22.5 37.1 31.9 24.8 27.8 11.2 32.3 20.1 41.9 8.2 60.2 37.8 34.8 1.7 26.4 38.1 36.6 53.5 30.5 28.9 19.4 29.2 22.3 25.2 28.1 63.1 51.1 13.9 39.3 31.9 27.7 33.0 19.6 25.1 50.0 20.0 36.1 21.1 39.7 39.8 26.6 0.0 19.7 24.2 11.4 30.3 55.2 33.7 24.6 25.0 45.2 38.7 85.3 38.1 25.7 22.6 48.1 25.5 1.7 3.3 3.9 0.4 5.5 0.3 2.3 0.8 1.4 1.6 0.7 0.7 0.6 9.9 1.4 5.7 0.8 0.6 0.5 18.8 15.5 24.8 23.5 18.3 14.7 19.2 19.4 15.2 16.3 17.6 14.9 24.5 6.4 13.7 12.7 10.5 16.7 7.4 9.5 9.6 25.5 22.0 18.4 13.7 15.7 9.0 23.9 18.8 7.5 20.1 44.4 7.9 9.4 154.9 18.0 18.1 15.7 15.0 27.3 7.9 14.0 5.3 13.2 21.9 17.8 2.5 80.3 15.4 31.6 15.2 18.5 8.5 33.1 6.1 18.3 26.4 338.7 24.5 20.7 16.0 11.2 20.4 21.2 9.2 9.0 6.5 16.7 29.3 20.7 10.2 15.1 27.5 11.0 9.3 21.0 13.1 21.5 23.7 85.5 20.1 14.6 15.5 8.8 16.6 45.2 35.4 12.6 STK19 "D6S60, G11, RP1" ENSG00000204344 "Serine/threonine kinase 19" P49842 6 31971091-31982821 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 4 "Proximal tubular cells: 348.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 1.4;HEL: 1.5;HL-60: 1.6;REH: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031511, HPA068559" Uncertain Supported "Nuclear speckles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 72: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA031511: AB_2673915, HPA068559: AB_2686004" "unprognostic (1.65e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-1)" "unprognostic (1.86e-1)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (1.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.40e-1)" "unprognostic (4.10e-1)" 1.5 3.6 0.1 0.2 0.1 0.0 1.3 0.4 0.9 2.1 0.0 2.5 0.0 1.4 0.3 1.9 1.0 0.1 1.2 0.0 0.0 1.5 2.2 1.3 0.0 0.0 0.0 1.1 1.1 0.2 1.4 0.4 0.1 2.1 0.0 0.2 0.9 0.1 1.3 2.5 0.7 0.0 0.0 1.2 1.3 1.5 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.4 0.0 0.1 0.0 0.4 1.1 0.7 0.0 0.3 0.1 0.2 0.4 0.0 0.7 0.6 0.3 0.5 0.0 0.6 0.0 0.2 0.3 1.4 0.4 1.5 0.3 0.0 0.5 1.6 0.0 0.6 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.1 0.4 0.0 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.9 0.0 0.7 0.2 0.0 0.0 1.1 0.0 0.1 0.3 0.2 0.6 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.3 0.4 0.4 0.0 0.1 0.1 0.1 0.4 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 21.2 9.6 21.5 13.7 16.4 13.0 14.0 23.0 13.6 11.8 26.6 27.6 8.1 18.6 24.6 22.0 20.9 37.2 22.4 13.8 39.2 26.3 85.8 27.8 31.8 20.6 19.3 4.6 8.7 28.3 20.0 23.3 19.4 20.7 9.5 20.1 14.3 21.1 19.3 10.1 8.0 17.3 18.3 8.8 10.0 76.0 20.2 18.3 17.8 11.2 12.5 30.2 13.4 4.5 6.5 23.6 16.4 18.4 11.9 13.2 15.0 348.9 41.8 21.9 32.9 19.6 21.1 39.5 21.0 17.9 18.2 49.7 19.8 45.1 13.1 11.8 STMN1 "C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN" ENSG00000117632 "Stathmin 1" P16949 1 25884181-25906991 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 951.6;lymphoid tissue: 1343.2" "Cell type enhanced" "Detected in all" "Late spermatids: 2537.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 424.6" "Group enriched" "Detected in all" 5 "dendritic cells: 424.6;T-cells: 143.3" "Cell line enhanced" "Detected in all" "MOLT-4: 3270.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010107, HPA068438" Enhanced Approved Cytosol NA NA 320000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB010107: AB_628297, HPA068438: " "unprognostic (6.30e-2)" "unprognostic (2.40e-3)" "unprognostic (5.31e-2)" "unprognostic (7.94e-2)" "unprognostic (1.89e-1)" "unprognostic (5.02e-2)" "prognostic unfavorable (9.90e-7)" "unprognostic (9.45e-2)" "unprognostic (1.39e-2)" "unprognostic (1.61e-2)" "unprognostic (1.78e-1)" "unprognostic (3.33e-3)" "unprognostic (1.02e-2)" "unprognostic (1.68e-1)" "unprognostic (4.46e-2)" "unprognostic (1.05e-1)" "unprognostic (3.00e-2)" 56.4 69.1 526.8 103.8 568.0 260.5 60.6 514.2 951.6 57.7 333.6 93.2 70.5 129.8 40.7 115.9 45.2 51.1 56.0 573.2 568.2 77.7 35.8 60.7 253.2 560.1 516.8 172.4 23.2 43.8 103.5 120.1 552.4 31.7 110.6 304.7 43.4 32.7 29.5 56.3 89.1 100.0 537.1 72.8 54.5 387.0 531.7 1343.2 33.6 29.9 246.0 58.9 76.0 791.9 1026.8 226.1 2191.0 882.5 128.9 126.0 225.7 776.3 609.7 1081.9 1037.9 157.2 1018.3 1260.3 426.3 572.0 425.8 304.6 618.6 450.9 1616.1 390.4 310.9 786.0 363.3 547.6 51.9 994.6 529.3 77.0 65.6 439.6 496.8 405.5 833.6 1594.4 1074.4 1203.0 1429.6 268.0 3270.7 1441.5 1350.8 615.1 302.8 1907.9 1709.2 740.7 536.9 91.7 1479.2 1282.3 710.0 348.3 638.4 695.8 500.7 1240.1 406.2 721.8 853.6 634.3 664.8 702.5 1212.0 1535.8 357.7 1904.8 798.2 13.4 4.1 23.5 53.9 8.6 32.2 37.0 47.8 68.2 23.2 45.6 77.8 71.6 1.9 56.3 4.5 424.6 143.3 57.2 526.8 568.0 514.2 951.6 573.2 568.2 560.1 516.8 552.4 537.1 531.7 791.9 257.3 41.7 31.6 32.7 125.1 201.6 148.9 350.0 577.7 454.6 91.0 175.1 77.2 31.5 100.0 174.7 64.6 439.3 261.7 35.1 226.9 148.9 917.2 92.8 100.3 196.3 250.8 505.7 109.5 20.1 604.1 134.9 121.3 141.1 262.0 712.4 109.2 15.4 530.1 195.2 73.0 100.9 567.6 87.3 287.0 2537.2 44.7 130.0 268.6 32.8 32.1 252.4 84.5 38.2 217.4 59.0 69.3 47.0 261.7 63.5 21.0 221.4 59.1 183.6 39.5 68.0 267.6 873.0 260.8 423.9 90.4 130.4 224.9 66.5 177.1 95.7 STRAP "MAWD, pt-wd, UNRIP" ENSG00000023734 "Serine/threonine kinase receptor associated protein" Q9Y3F4 12 15882387-15903478 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027320, HPA055557, HPA073876" Approved Enhanced Cytosol NA NA 200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA027320: AB_1857614, HPA055557: AB_2682849, HPA073876: AB_2686639" "unprognostic (4.64e-3)" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (1.42e-2)" "unprognostic (2.88e-1)" "unprognostic (4.05e-3)" "prognostic unfavorable (6.83e-6)" "unprognostic (1.69e-2)" "unprognostic (3.71e-1)" "unprognostic (2.15e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (3.60e-3)" "unprognostic (5.93e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (9.07e-4)" "prognostic unfavorable (5.10e-4)" 70.4 70.2 48.1 54.7 52.5 51.8 49.8 44.4 63.7 51.8 41.4 55.5 46.2 52.2 50.5 60.9 44.4 46.9 93.1 54.8 65.3 84.9 80.3 46.8 54.9 49.9 54.5 40.3 72.0 83.9 58.4 64.6 61.6 49.3 52.8 85.5 48.8 48.7 135.9 44.1 44.9 68.8 47.6 40.3 48.5 50.3 59.0 66.5 77.7 114.6 57.2 70.4 41.3 50.9 195.6 226.2 209.7 179.8 182.3 180.6 280.5 227.9 158.2 200.8 186.4 325.9 167.2 215.6 110.6 233.5 199.3 138.0 254.6 251.0 293.2 291.3 206.1 218.6 163.8 144.7 298.8 258.2 102.0 176.9 209.7 224.6 248.6 221.6 237.9 139.6 170.9 63.9 264.3 137.3 215.6 122.6 743.6 124.8 145.8 162.4 289.7 124.5 232.5 197.8 134.8 228.8 184.7 125.5 258.7 415.8 235.5 135.9 201.3 149.0 177.0 160.3 284.7 73.0 106.1 351.5 183.7 140.1 193.9 74.2 73.9 65.8 66.3 87.4 75.1 76.1 67.8 64.2 92.5 66.7 65.8 70.0 33.7 64.3 80.5 56.8 92.2 84.5 48.1 52.5 44.4 63.7 54.8 65.3 49.9 54.5 61.6 47.6 59.0 50.9 111.7 38.5 45.2 19.9 111.2 243.4 177.6 131.5 116.7 90.1 87.8 65.9 104.0 51.5 84.8 66.2 35.5 154.3 121.2 41.5 275.9 171.1 44.3 63.2 82.1 100.3 106.2 103.7 42.8 137.2 201.2 109.7 61.7 78.6 46.3 112.1 71.7 82.1 108.8 60.6 43.4 59.7 128.1 86.2 143.8 86.2 69.9 89.4 128.1 22.5 99.2 207.9 93.7 24.1 33.9 144.2 66.1 102.0 119.5 218.3 56.0 228.5 58.9 100.9 78.9 96.4 139.0 168.1 80.4 115.6 227.9 295.1 111.3 135.2 95.6 192.5 STRN "PPP2R6A, STRN1" ENSG00000115808 Striatin O43815 2 36837698-36966536 "Cancer-related genes, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017286 Approved Approved Nucleoplasm,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Nucleoplasm "HPA017286: AB_1857618" "unprognostic (1.65e-1)" "unprognostic (1.65e-1)" "unprognostic (3.57e-3)" "unprognostic (2.23e-2)" "unprognostic (3.25e-1)" "unprognostic (1.53e-1)" "unprognostic (1.63e-3)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" "unprognostic (2.42e-1)" "unprognostic (1.77e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.13e-1)" "unprognostic (6.43e-2)" "unprognostic (2.11e-1)" "unprognostic (3.43e-2)" 8.4 4.7 5.3 9.4 16.7 14.9 8.6 11.9 9.0 8.6 0.6 9.1 8.1 6.2 3.8 21.2 5.3 6.8 21.2 5.5 10.2 8.4 7.5 7.8 7.7 13.0 11.6 7.7 5.6 7.3 2.4 10.1 13.1 5.5 10.7 10.1 10.7 5.0 11.6 11.2 8.6 7.7 9.8 8.1 9.0 8.0 14.2 13.3 6.2 11.5 12.6 8.4 10.1 24.7 38.3 19.0 25.2 10.4 13.3 18.0 24.6 14.8 14.2 14.5 13.3 19.4 12.2 24.7 11.8 19.7 20.6 17.6 21.4 17.0 17.9 27.9 16.0 40.2 16.4 10.3 12.1 24.9 21.8 11.4 12.9 23.2 18.3 10.7 18.6 10.0 30.4 19.2 18.2 11.1 24.7 7.4 19.8 15.7 9.4 15.9 38.5 11.2 9.7 31.0 4.5 15.1 22.4 16.9 13.6 13.7 12.2 9.2 24.9 25.4 25.4 16.0 20.1 19.5 31.0 21.6 13.2 23.2 18.2 1.3 0.2 0.4 0.5 0.4 0.2 0.4 0.4 0.3 0.1 0.2 0.2 0.2 1.0 0.2 0.4 0.2 0.1 0.1 5.3 16.7 11.9 9.0 5.5 10.2 13.0 11.6 13.1 9.8 14.2 24.7 26.5 9.6 10.0 38.8 18.8 20.6 12.3 11.3 21.6 12.7 16.0 9.4 55.4 8.6 17.4 23.9 20.9 8.0 22.8 25.0 9.8 10.5 1.9 14.2 14.3 19.4 11.4 26.5 65.3 8.4 10.3 13.6 20.4 26.2 5.1 16.0 16.4 7.9 8.8 18.5 55.2 17.8 10.2 20.7 10.0 2.1 9.6 18.0 8.8 47.8 20.3 10.1 35.0 55.3 294.0 16.8 14.1 12.4 14.3 19.3 13.0 8.5 8.2 16.9 0.0 13.6 16.5 15.2 19.2 31.4 33.2 16.3 19.4 17.7 16.0 39.4 STT3A "ITM1, MGC9042, STT3-A, TMC" ENSG00000134910 "STT3 oligosaccharyltransferase complex catalytic subunit A" P46977 11 125591712-125625215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 391.8" "Cell type enhanced" "Detected in all" "Plasma cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030735 Approved NA NA 23000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" "HPA030735: AB_10603342" "unprognostic (8.25e-3)" "unprognostic (5.45e-2)" "unprognostic (3.02e-2)" "prognostic favorable (1.32e-4)" "unprognostic (5.10e-2)" "unprognostic (1.72e-2)" "prognostic unfavorable (3.57e-4)" "unprognostic (8.40e-2)" "unprognostic (4.80e-2)" "unprognostic (1.16e-2)" "unprognostic (8.96e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.60e-2)" "unprognostic (6.38e-2)" "unprognostic (1.28e-1)" "unprognostic (1.82e-2)" 38.5 39.2 14.6 44.6 17.7 31.8 55.8 17.9 16.9 84.9 29.8 54.0 42.2 60.8 140.4 30.2 56.3 39.5 38.5 15.0 20.1 45.8 69.0 39.0 32.9 19.4 18.4 68.0 69.0 391.8 29.0 63.8 19.6 56.2 59.5 40.0 80.1 77.2 18.4 31.6 42.1 58.9 17.5 34.4 51.4 44.5 17.5 34.8 83.9 24.4 48.8 50.4 33.3 23.1 113.1 99.5 123.7 173.6 230.1 176.4 133.8 198.5 238.5 158.6 196.6 304.2 294.3 143.6 236.2 297.3 222.4 202.7 173.5 176.2 208.5 114.8 90.0 341.0 63.7 215.1 254.4 208.4 153.6 138.4 125.8 219.5 424.5 186.1 182.2 63.9 147.1 210.6 205.4 82.7 84.4 65.6 78.6 221.8 106.0 98.9 107.1 221.5 173.7 170.1 77.5 66.2 142.9 229.3 72.5 144.9 267.8 148.1 164.5 227.7 82.0 97.6 159.7 66.3 82.4 109.6 87.4 206.3 184.7 96.2 46.7 36.6 56.1 45.4 77.9 42.8 53.7 52.0 65.2 32.1 37.1 44.4 15.7 52.8 41.8 158.3 44.0 47.5 14.6 17.7 17.9 16.9 15.0 20.1 19.4 18.4 19.6 17.5 17.5 23.1 17.4 28.9 25.0 6.8 20.8 16.2 14.3 40.3 12.5 11.6 15.2 9.8 23.3 27.1 29.1 16.5 20.9 45.4 21.7 16.1 1.9 30.1 10.6 22.9 51.0 17.3 15.6 19.6 7.6 27.2 73.4 33.0 26.0 57.0 17.1 29.0 32.2 38.5 30.7 1.7 8.9 37.3 20.3 23.6 31.9 5.4 21.5 17.3 24.9 9.4 12.6 13.2 11.3 11.6 10.9 28.6 12.2 18.8 91.9 19.3 15.6 13.6 23.6 15.1 19.7 23.1 32.8 33.5 13.1 21.9 14.8 45.6 14.6 22.3 26.9 13.9 STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839266 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 152.2;Endometrial ciliated cells: 86.4;Late spermatids: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" 17.7 11.0 11.2 9.1 11.7 6.4 12.0 12.3 13.4 15.1 24.7 21.2 4.2 14.3 9.8 6.0 16.3 9.9 17.0 12.2 12.1 14.4 13.3 17.8 8.6 15.5 12.3 15.3 10.9 5.9 14.6 13.2 14.5 8.4 6.8 16.7 5.0 10.6 6.7 5.1 11.4 17.2 13.0 12.4 11.4 17.0 11.8 6.9 12.4 7.9 6.2 14.5 10.7 16.3 9.6 18.3 26.8 22.4 27.8 63.2 2.8 44.2 35.8 50.8 35.7 5.5 6.6 11.7 6.6 50.5 16.4 2.8 24.4 6.6 54.9 18.7 9.2 6.4 15.9 15.7 30.6 9.2 15.5 23.4 8.3 24.9 20.1 48.2 27.6 12.7 25.7 11.2 46.2 5.6 13.3 10.6 17.9 2.9 28.2 13.7 18.9 7.0 28.7 2.1 24.3 25.4 20.4 1.8 18.1 23.4 6.1 6.4 36.5 30.1 20.3 33.1 19.6 8.1 6.7 7.9 35.0 10.8 24.4 1.0 0.4 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.3 0.3 0.6 0.6 0.4 0.2 0.2 0.3 0.4 0.2 11.2 11.7 12.3 13.4 12.2 12.1 15.5 12.3 14.5 13.0 11.8 16.3 35.3 22.4 14.8 20.5 6.2 3.4 1.2 2.1 3.4 5.6 2.1 3.0 17.2 11.5 6.9 29.5 0.0 1.8 12.3 0.4 9.8 19.1 152.2 86.4 40.0 22.4 6.7 32.4 33.6 7.4 7.1 26.5 2.6 7.6 1.3 10.9 17.9 19.0 11.5 0.0 17.6 0.7 2.0 11.5 12.3 114.4 28.0 15.1 14.2 23.4 10.3 12.3 6.2 15.1 24.3 14.5 0.1 24.5 10.2 2.0 0.1 17.6 33.9 31.4 13.1 26.1 29.6 42.0 34.2 1.7 1.4 0.8 14.2 11.7 0.6 0.5 SUFU "PRO1280, SUFUH, SUFUXL" ENSG00000107882 "SUFU negative regulator of hedgehog signaling" Q9UMX1 10 102503972-102633535 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ciliopathy, Disease variant, Joubert syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 129.2;Late spermatids: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008700 Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA008700: AB_1080125" "unprognostic (1.55e-1)" "unprognostic (4.00e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-1)" "unprognostic (4.69e-2)" "unprognostic (5.68e-2)" "unprognostic (3.69e-2)" "unprognostic (5.99e-2)" "unprognostic (1.64e-1)" "unprognostic (3.15e-3)" "unprognostic (9.60e-2)" "unprognostic (2.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-2)" "unprognostic (3.82e-3)" 6.6 7.2 8.8 7.1 8.5 2.0 6.1 8.9 8.0 8.6 5.5 6.8 3.9 7.4 4.9 9.2 7.1 6.6 6.3 7.8 7.3 6.1 6.2 5.8 7.2 8.3 8.2 8.9 4.1 11.1 4.3 7.4 7.8 8.5 4.4 4.6 7.1 5.2 8.6 14.4 5.7 7.3 6.7 7.4 4.6 11.5 8.0 7.8 3.4 7.3 8.1 8.8 9.2 7.3 8.7 9.1 14.4 20.8 14.5 12.1 7.0 8.8 17.0 12.5 11.3 8.5 6.3 8.9 24.5 9.9 5.0 6.0 17.8 9.8 8.2 5.5 13.8 21.2 5.2 8.0 6.9 7.7 14.6 13.9 7.5 9.3 7.5 22.9 16.3 8.5 4.8 7.9 7.8 7.2 14.8 11.6 4.1 5.6 6.7 15.8 15.5 4.7 8.3 12.8 4.8 7.8 7.0 6.4 8.1 13.1 14.2 5.0 18.1 5.5 7.8 6.0 9.8 6.4 4.5 6.4 6.9 14.9 3.8 2.0 2.0 2.9 1.0 2.4 0.8 0.9 1.2 1.1 1.9 0.8 0.8 1.0 0.4 1.1 2.5 1.1 0.8 1.4 8.8 8.5 8.9 8.0 7.8 7.3 8.3 8.2 7.8 6.7 8.0 7.3 3.3 0.0 3.7 28.7 4.9 3.1 2.1 2.9 6.8 4.2 3.5 3.0 4.0 1.5 4.6 3.7 8.4 7.8 3.1 3.5 1.9 4.4 129.2 4.5 6.2 5.1 1.2 2.5 25.9 3.0 3.5 6.0 4.6 8.5 3.8 3.8 10.8 5.4 12.4 1.7 22.2 2.2 0.0 9.4 6.3 115.9 5.0 8.7 0.0 32.8 7.8 2.7 4.1 17.6 16.8 4.1 1.3 6.8 4.0 2.0 5.7 5.8 5.7 4.8 0.0 3.0 4.5 8.7 5.3 8.9 6.5 7.0 7.1 7.6 3.0 1.3 SULT1E1 "EST, STE" ENSG00000109193 "Sulfotransferase family 1E member 1" P49888 4 69841212-69860145 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.5;liver: 37.2;skin 1: 19.3;vagina: 30.4" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 65.8;Glandular and luminal cells: 35.1;Hepatocytes: 51.4;Paneth cells: 66.3;Proximal enterocytes: 21.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HHSteC: 71.1;HSkMC: 32.3;hTCEpi: 27.3;HUVEC TERT2: 20.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 7.8" "HPA028213, HPA028728, CAB047344" Enhanced Uncertain "Nuclear membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Nuclear membrane, Cytosol" "CAB047344: , HPA028213: AB_10599848, HPA028728: AB_10601894" "unprognostic (5.60e-2)" "prognostic favorable (4.06e-4)" "unprognostic (2.48e-1)" "unprognostic (1.07e-3)" "unprognostic (2.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.70e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (3.22e-3)" "unprognostic (8.62e-2)" "unprognostic (6.48e-5)" "unprognostic (2.48e-1)" "unprognostic (4.11e-2)" "unprognostic (5.55e-2)" 0.1 14.5 0.1 0.0 0.1 0.1 0.1 0.1 0.2 13.5 4.1 0.2 27.5 0.3 1.0 0.8 0.2 0.2 0.0 0.1 0.0 0.3 37.2 2.3 0.0 0.1 0.1 0.0 0.2 0.0 0.6 0.1 0.1 0.7 0.1 0.0 6.6 0.4 0.0 19.3 27.3 0.1 0.0 0.0 2.1 0.1 0.1 0.5 0.0 0.0 1.5 0.7 30.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 71.1 0.0 0.0 32.3 27.3 0.0 0.9 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 11.9 1.0 8.7 0.0 0.0 0.1 0.0 0.1 1.5 2.8 1.8 0.0 0.2 0.0 0.2 0.0 0.0 0.0 65.8 1.3 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.0 35.1 0.0 0.0 2.5 51.4 0.3 0.0 0.0 4.7 0.0 0.8 0.7 0.0 0.3 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 66.3 0.0 0.0 0.0 21.5 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 3.4 1.5 0.1 0.0 13.8 0.2 SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim, Nuclear bodies" "HPA057436: AB_2683439" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (7.31e-2)" "unprognostic (2.66e-3)" "unprognostic (8.05e-2)" "unprognostic (7.27e-2)" "unprognostic (3.06e-2)" "unprognostic (6.29e-2)" "unprognostic (8.70e-2)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (1.31e-1)" 12.3 11.8 6.3 18.8 6.3 45.4 15.0 11.1 8.5 11.6 6.8 14.9 16.0 15.2 12.0 14.0 11.0 12.0 10.3 5.4 5.8 16.4 18.1 12.6 33.0 5.4 5.9 11.4 11.5 19.8 6.6 18.7 5.6 13.3 16.4 26.5 10.5 12.2 8.1 13.0 15.3 14.7 5.2 18.4 15.2 27.4 6.1 38.5 18.3 11.0 30.0 15.6 9.0 7.1 46.5 40.4 37.2 42.9 21.1 26.8 38.2 44.2 38.8 53.0 63.7 30.9 25.5 100.7 33.2 27.7 45.4 40.1 56.0 25.5 85.7 35.8 54.0 69.9 32.9 22.3 24.8 111.5 68.7 18.7 28.1 53.1 40.4 32.1 33.1 47.3 68.8 135.6 46.2 16.2 133.3 64.4 21.3 32.4 24.4 78.5 95.3 81.9 31.1 44.6 47.5 37.1 71.3 22.7 43.3 25.8 66.0 91.5 24.7 41.9 38.0 50.8 69.3 73.5 98.4 122.5 30.7 67.4 38.7 0.6 0.7 1.6 1.4 1.1 1.1 2.4 1.6 1.6 0.6 1.8 1.5 2.1 1.6 1.8 0.7 1.9 1.8 0.4 6.3 6.3 11.1 8.5 5.4 5.8 5.4 5.9 5.6 5.2 6.1 7.1 44.5 41.7 45.8 43.1 50.1 58.5 50.2 21.8 31.9 77.6 54.2 36.8 32.3 27.1 32.6 35.0 108.4 61.5 65.2 24.0 17.6 28.3 16.2 52.8 55.8 45.1 29.4 93.6 71.6 21.9 53.1 35.1 31.1 54.2 15.8 41.4 38.2 42.3 32.9 62.2 69.5 31.8 10.2 42.1 58.2 13.9 26.8 47.3 24.9 45.0 73.1 45.7 38.1 75.4 71.3 27.8 15.4 25.6 66.2 62.8 21.5 26.6 29.6 80.9 13.1 47.2 38.4 121.7 128.9 48.6 71.7 69.5 52.5 52.8 35.6 66.7 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.3;Hofbauer cells: 73.1;Kupffer cells: 96.7;Macrophages: 95.2;Microglial cells: 114.3;monocytes: 92.5;Plasma cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 125.8;HEL: 72.8;HL-60: 101.6;HMC-1: 64.1;REH: 84.4;THP-1: 76.8;U-698: 58.8;U-937: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.4 4.6 4.1 42.5 4.1 50.9 6.8 4.5 4.9 7.7 4.2 20.1 30.8 4.1 16.1 17.5 17.0 12.9 2.9 3.8 5.0 11.2 4.5 20.6 61.8 7.1 5.8 1.7 9.1 87.6 2.4 12.0 7.0 3.8 20.5 0.7 8.4 4.2 1.0 9.9 36.3 9.3 6.6 40.3 19.1 6.9 7.1 49.7 25.6 2.4 73.8 17.5 8.3 9.8 22.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 14.3 125.8 3.5 0.0 4.2 19.1 2.7 10.2 0.0 0.0 17.0 72.8 0.0 0.0 0.0 101.6 64.1 0.0 14.0 0.0 1.4 0.0 0.0 15.5 2.0 9.9 0.0 15.4 0.1 44.4 0.7 47.0 0.0 84.4 0.1 34.6 2.6 18.6 6.4 5.7 0.1 8.7 0.1 0.3 7.9 76.8 0.2 0.0 0.4 0.1 0.1 0.2 0.0 58.8 0.0 70.3 0.0 5.3 77.3 83.5 0.3 64.0 0.3 74.5 0.2 0.2 85.1 58.4 0.2 0.1 112.1 30.0 60.2 63.2 0.1 44.6 4.1 4.1 4.5 4.9 3.8 5.0 7.1 5.8 7.0 6.6 7.1 9.8 0.5 12.8 20.2 0.0 91.3 3.4 3.7 8.7 12.0 1.4 6.3 2.8 1.6 14.3 12.8 14.7 0.0 1.3 70.4 16.5 15.6 15.0 7.1 10.7 1.0 2.1 10.3 37.9 0.4 12.5 2.6 2.1 22.4 12.6 43.6 0.0 3.3 1.0 73.1 0.0 0.7 24.4 0.0 96.7 28.8 6.2 0.6 95.2 12.4 114.3 92.5 0.0 62.8 1.5 0.5 18.2 25.1 0.0 83.1 2.5 31.4 0.4 10.4 0.2 6.6 0.7 2.3 0.8 0.7 30.4 5.7 1.4 8.3 0.0 31.1 8.0 SYNE1 "8B, ARCA1, C6orf98, CPG2, dJ45H2.2, enaptin, KIAA0796, MYNE1, Nesp1, Nesprin-1, SCAR8, SYNE-1B" ENSG00000131018 "Spectrin repeat containing nuclear envelope protein 1" Q8NF91 6 152121684-152637801 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" Actin-binding "Cancer-related genes, Disease variant, Emery-Dreifuss muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.5;choroid plexus: 182.9" "Cell type enhanced" "Detected in many" "Astrocytes: 550.1;Bipolar cells: 332.1;Excitatory neurons: 494.6;Inhibitory neurons: 482.6;Microglial cells: 315.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 56.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 56.8" "Cell line enhanced" "Detected in many" "U-2 OS: 29.8;U-266/70: 29.1" "Low region specificity" "Detected in all" HPA019113 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 72000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Nuclear membrane" "HPA019113: AB_1857707" "unprognostic (9.99e-2)" "unprognostic (1.91e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-1)" "unprognostic (2.28e-1)" "unprognostic (9.58e-3)" "unprognostic (1.11e-1)" "unprognostic (3.55e-3)" "unprognostic (1.58e-1)" "unprognostic (9.85e-2)" "unprognostic (8.87e-3)" "unprognostic (2.70e-1)" "unprognostic (4.14e-3)" "unprognostic (5.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" 15.4 17.8 60.2 7.5 68.8 53.6 14.4 152.5 70.2 18.9 182.9 17.2 2.3 19.1 23.7 5.6 26.4 7.9 32.3 92.4 58.1 34.7 14.6 31.3 17.1 55.0 58.8 44.5 20.6 23.6 56.8 4.4 55.6 17.0 6.2 66.3 5.0 12.6 28.0 19.6 11.4 13.1 38.3 32.9 21.6 17.6 55.4 23.9 44.7 16.5 13.4 16.3 12.9 51.5 0.2 5.8 3.7 4.4 5.7 12.1 1.5 14.7 6.9 3.4 6.0 1.3 0.2 13.5 0.7 7.5 11.2 0.3 1.6 3.8 3.5 11.6 4.0 5.2 4.1 4.0 12.8 1.1 2.7 7.9 0.8 7.5 14.9 9.2 6.8 6.9 0.0 14.2 9.2 0.7 2.4 0.2 0.9 1.3 2.2 2.9 8.1 3.5 15.7 0.2 2.6 3.9 2.7 0.8 9.8 3.7 0.8 0.5 9.0 16.3 29.8 5.9 7.6 29.1 12.5 23.3 8.8 2.9 4.6 10.2 2.3 56.8 11.8 1.8 7.9 6.9 10.3 13.4 1.8 8.2 9.7 10.9 1.6 9.9 3.9 1.5 13.2 3.5 60.2 68.8 152.5 70.2 92.4 58.1 55.0 58.8 55.6 38.3 55.4 51.5 139.7 166.7 215.2 550.1 29.1 12.7 5.4 3.0 3.4 332.1 4.9 9.7 117.2 7.2 53.1 44.1 200.1 0.9 132.9 0.4 3.9 24.0 11.5 132.0 118.2 127.5 3.0 11.6 494.6 7.7 14.2 79.6 7.7 17.8 15.2 13.1 90.0 21.8 8.0 138.0 482.6 11.5 2.0 10.1 15.0 12.6 33.2 16.0 16.0 315.7 12.8 27.3 210.1 256.4 108.6 4.2 0.1 39.9 79.6 5.1 0.0 17.8 146.7 145.5 26.3 145.8 85.6 3.9 5.7 2.2 9.7 1.2 74.7 62.2 0.4 2.2 TAF1 "BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250" ENSG00000147133 "TATA-box binding protein associated factor 1" P21675 X 71366264-71532374 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dystonia, Mental retardation, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA001075, CAB016283" Supported Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB016283: AB_671202, HPA001075: AB_1080179" "unprognostic (2.95e-2)" "unprognostic (1.77e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-2)" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "prognostic favorable (6.54e-4)" "unprognostic (2.68e-2)" "unprognostic (3.43e-2)" "unprognostic (2.03e-1)" "unprognostic (5.59e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (1.14e-2)" "unprognostic (1.41e-1)" "unprognostic (1.82e-2)" "unprognostic (2.56e-2)" 10.9 8.6 10.3 11.4 12.7 12.8 12.3 13.7 11.1 11.1 10.2 10.0 6.6 13.8 12.9 7.5 11.1 7.8 7.0 9.3 14.1 7.5 7.8 9.1 14.1 11.5 11.3 14.4 9.8 12.2 8.4 10.0 10.9 10.0 10.0 27.3 7.7 10.1 10.5 13.3 9.3 10.9 8.2 15.4 10.6 7.2 12.5 14.8 12.7 10.3 12.4 9.2 8.6 16.8 18.6 15.9 18.2 12.4 14.6 23.2 11.0 13.3 12.1 13.7 11.1 12.3 11.3 17.6 11.5 14.9 12.3 17.5 24.1 11.0 17.0 11.2 21.9 20.1 22.1 13.1 11.1 39.7 19.4 14.1 11.3 14.2 27.2 12.8 14.7 13.2 28.2 41.1 14.4 14.5 22.4 25.4 20.9 23.5 20.8 19.8 35.8 21.6 11.1 25.0 9.0 14.5 37.7 13.6 18.7 14.3 9.6 22.9 18.6 16.5 14.2 13.4 9.7 17.5 17.4 21.4 9.0 33.2 12.5 1.6 1.4 0.7 1.4 0.9 1.3 1.0 1.4 1.4 1.5 1.5 1.6 1.8 1.8 1.5 1.6 1.4 1.0 0.7 10.3 12.7 13.7 11.1 9.3 14.1 11.5 11.3 10.9 8.2 12.5 16.8 26.7 32.1 26.7 44.7 21.2 11.9 8.9 10.4 18.2 37.5 12.5 13.3 17.2 10.0 23.9 3.7 81.3 8.6 21.5 7.8 1.9 6.3 2.5 17.0 23.4 24.6 11.4 28.6 54.3 7.0 5.9 17.6 12.2 18.9 23.4 23.9 18.9 12.6 8.8 16.8 52.2 14.6 6.1 16.2 20.0 2.6 22.1 20.4 5.4 47.8 23.9 17.0 29.9 49.3 79.1 7.6 13.3 22.2 18.7 11.2 13.4 5.2 14.8 67.9 0.0 27.4 18.0 9.3 10.7 17.8 17.3 5.7 23.8 25.9 13.6 9.6 TAF15 "hTAFII68, Npl3, RBP56, TAF2N" ENSG00000270647 "TATA-box binding protein associated factor 15" Q92804 17 35713791-35864615 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052059, HPA063647" Supported Enhanced Nucleoplasm NA NA 44000 "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA052059: AB_2681711, HPA063647: AB_2685072" "unprognostic (1.26e-1)" "unprognostic (2.66e-3)" "unprognostic (1.10e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (8.48e-3)" "unprognostic (4.75e-2)" "unprognostic (8.06e-3)" "unprognostic (2.08e-2)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (1.79e-2)" "unprognostic (1.39e-2)" "unprognostic (5.41e-2)" "unprognostic (3.35e-2)" "unprognostic (2.99e-1)" 62.0 74.8 56.2 74.5 54.4 69.2 57.3 52.9 68.4 74.3 55.2 71.9 56.4 69.9 40.9 102.7 61.6 33.4 80.2 52.0 61.1 63.8 82.1 57.2 90.0 56.3 56.9 66.0 74.0 54.4 71.3 48.2 55.8 63.0 48.6 54.2 65.8 38.2 130.2 80.0 78.6 38.0 54.3 76.4 76.6 87.8 56.1 95.5 58.5 38.3 75.2 74.6 72.1 57.0 216.8 347.3 190.2 191.2 149.6 88.5 108.3 247.9 79.1 109.7 107.0 244.5 151.1 440.1 166.9 145.2 122.2 239.6 254.0 232.8 166.0 112.9 187.1 250.6 264.3 261.1 145.3 401.1 168.4 135.7 143.6 155.3 266.0 137.0 140.1 238.5 233.3 188.9 148.1 270.4 442.0 96.0 117.0 205.9 40.2 255.7 279.6 164.7 149.3 399.1 130.1 136.6 299.6 97.8 98.3 231.0 224.5 144.9 214.1 86.1 178.3 115.8 310.1 165.6 198.4 303.4 173.7 190.1 134.1 1.4 1.0 1.2 1.7 1.4 2.0 1.0 1.0 1.2 0.7 1.2 0.9 1.2 0.9 2.0 1.5 1.0 1.5 0.9 56.2 54.4 52.9 68.4 52.0 61.1 56.3 56.9 55.8 54.3 56.1 57.0 38.1 16.0 55.1 90.4 71.4 36.1 59.7 57.9 93.9 57.8 29.3 31.0 41.6 40.0 57.0 60.7 41.7 82.1 63.1 38.4 3.9 42.7 7.5 51.4 55.0 52.6 49.1 75.3 108.4 29.6 50.8 36.9 66.3 53.8 55.8 32.4 36.8 60.7 43.1 60.6 111.7 52.2 46.8 44.0 32.9 10.4 30.7 49.0 33.8 78.7 56.0 75.1 54.6 100.0 124.2 29.2 29.4 40.6 53.2 43.4 50.3 31.6 47.2 45.4 46.0 48.0 51.7 84.9 74.7 115.3 37.2 78.0 78.8 55.6 58.5 44.8 TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 9628.1;intestine: 11712.2" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 2508.6;Peritubular cells: 2306.4;Sertoli cells: 2866.2;Smooth muscle cells: 4563.9" "Cancer enhanced" "Detected in all" "prostate cancer: 279.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 41.6;non-classical monocyte: 63.1" "Lineage enriched" "Detected in many" 12 "monocytes: 63.1" "Cell line enhanced" "Detected in all" "BJ: 1913.4;BJ hTERT+ SV40 Large T+: 1641.8;CACO-2: 1531.4;EFO-21: 2145.6;fHDF/TERT166: 2094.4;hTERT-RPE1: 1499.7;LHCN-M2: 1377.1;U-138 MG: 1598.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467" Enhanced Approved Microtubules,Mitochondria,Cytosol No No 6300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Mitochondria" Cytosol "CAB001447: AB_564012, HPA019467: AB_1857245" "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-1)" "unprognostic (6.58e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (9.58e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-3)" 2235.7 512.7 118.5 963.9 144.4 12.1 1680.5 126.1 215.9 3611.3 172.5 11712.2 451.2 9628.1 693.9 1954.6 4610.6 893.8 1583.5 119.6 120.4 774.5 302.8 1258.6 245.5 137.0 127.0 1643.4 218.6 65.3 254.6 348.0 129.2 4624.1 1154.6 22.9 461.8 6383.6 356.4 619.8 1948.4 7108.7 127.2 532.0 3148.4 202.5 138.2 52.2 723.2 152.4 59.9 5521.7 2331.2 130.0 17.5 5.5 293.3 8.2 140.0 123.8 226.7 1913.4 788.1 1641.8 609.0 1531.4 28.4 3.2 2145.6 2094.4 1.7 46.1 4.4 16.8 543.3 6.8 4.4 5.0 66.9 130.2 708.7 1.7 5.2 304.6 57.5 267.1 36.1 1499.7 3.3 4.5 3.3 6.7 1377.1 4.5 1.7 15.8 84.6 18.8 2.1 2.7 23.1 12.0 4.4 25.8 1.9 9.6 29.9 11.0 1.5 807.6 9.2 5.1 182.0 1598.8 276.9 14.4 86.6 8.9 8.8 21.7 9.1 7.7 6.2 1.8 2.7 0.1 0.3 41.6 0.5 3.6 0.1 0.0 3.2 5.1 0.2 0.1 0.3 0.0 63.1 1.6 0.5 2.1 118.5 144.4 126.1 215.9 119.6 120.4 137.0 127.0 129.2 127.2 138.2 130.0 264.8 38.5 6.1 4.6 10.3 63.9 453.4 248.6 10.8 9.9 74.0 2508.6 1.3 4.3 22.5 40.5 18.8 57.0 8.6 3.1 0.0 577.8 3.3 14.6 455.5 260.3 3.0 2.7 4.5 74.5 35.3 464.4 41.3 12.8 1.3 32.4 639.7 8.9 41.5 1.7 6.5 18.3 24.4 23.1 91.8 23.9 48.4 33.8 96.0 37.5 8.1 4.9 2.1 3.0 11.9 38.4 4.5 2306.4 3.2 414.0 12.1 2.2 23.0 9.9 2866.2 177.6 4563.9 6.0 13.7 8.6 60.9 32.2 15.1 8.3 3.1 62.0 TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 153.7;HMC-1: 70.6;HUVEC TERT2: 31.2;JURKAT: 60.0;K-562: 48.9;MOLT-4: 26.3;TIME: 34.4" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" 7.5 2.5 4.9 1.0 4.5 29.4 6.3 4.7 4.4 2.9 3.0 2.1 0.8 2.9 0.6 1.8 3.5 2.3 5.9 4.6 4.6 4.4 1.5 13.0 1.4 6.5 7.1 1.2 0.9 0.9 1.7 6.9 6.8 2.1 1.3 0.2 1.1 0.8 2.1 1.7 3.1 2.7 6.9 7.1 1.8 0.9 6.4 0.4 5.4 2.5 0.7 2.4 2.5 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.2 0.1 153.7 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 0.0 0.0 31.2 60.0 48.9 0.1 0.0 0.0 26.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.1 34.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.5 4.9 4.5 4.7 4.4 4.6 4.6 6.5 7.1 6.8 6.9 6.4 6.8 23.9 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.5 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.1 18.1 0.0 151.5 0.0 0.0 0.3 0.6 0.0 0.0 36.8 0.0 26.7 0.1 10.6 0.0 0.1 0.0 0.0 1.6 1.5 18.2 0.0 4.8 1.8 29.0 0.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 1.3 0.4 0.1 1.0 0.0 2.0 0.0 0.0 0.0 TAL2 bHLHa19 ENSG00000186051 "TAL bHLH transcription factor 2" Q16559 9 105662457-105663124 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 13.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Distal tubular cells: 7.9;Enteroendocrine cells: 3.5;Muller glia cells: 2.7;Proximal tubular cells: 2.3" "Group enriched" "Detected in some" 4 "renal cancer: 1.6;testis cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 6.9;naive B-cell: 7.3" "Lineage enriched" "Detected in many" 4 "B-cells: 7.3" "Cell line enhanced" "Detected in some" "CACO-2: 2.1;HAP1: 2.9;K-562: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA030886 Uncertain Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA030886: AB_10601596" "unprognostic (3.89e-2)" "unprognostic (1.45e-1)" "unprognostic (8.51e-2)" "unprognostic (5.54e-2)" "unprognostic (2.24e-1)" "unprognostic (9.06e-2)" "unprognostic (4.98e-2)" "unprognostic (1.03e-1)" "unprognostic (2.70e-3)" "unprognostic (2.63e-1)" "unprognostic (7.00e-4)" "unprognostic (2.84e-2)" "prognostic favorable (2.69e-4)" "unprognostic (2.70e-2)" "unprognostic (1.24e-1)" "unprognostic (1.29e-1)" "unprognostic (7.39e-2)" 0.1 0.2 0.4 0.1 0.5 0.0 0.1 0.3 0.9 0.2 1.3 0.1 0.0 0.1 0.6 0.1 0.2 0.0 0.2 0.5 0.5 3.0 0.2 0.1 0.2 0.5 0.6 0.3 0.1 0.0 0.4 0.1 0.6 0.1 0.1 0.5 0.1 0.1 13.7 0.1 0.1 0.0 0.4 0.2 0.1 0.3 0.4 0.1 0.1 2.4 0.3 0.1 0.1 0.7 0.0 0.4 1.5 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.2 2.1 0.1 0.0 0.1 0.0 0.4 0.0 2.9 0.0 0.1 0.4 0.3 0.7 0.0 0.0 0.1 0.3 1.1 0.1 0.3 0.1 0.1 0.1 0.0 0.5 8.2 0.2 0.2 0.2 0.5 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.7 0.1 0.1 0.1 0.0 0.2 1.3 0.3 0.2 0.4 0.4 0.6 0.6 1.2 0.0 0.1 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.4 0.5 0.3 0.9 0.5 0.5 0.5 0.6 0.6 0.4 0.4 0.7 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.0 0.4 0.1 0.2 0.0 0.0 0.0 4.2 0.0 0.1 0.0 7.9 0.1 0.1 0.0 0.2 0.0 3.5 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.2 0.0 0.4 0.1 0.0 0.0 2.3 0.0 1.0 0.0 0.8 0.1 0.6 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TAP1 "ABCB2, D6S114E, PSF1, RING4" ENSG00000168394 "Transporter 1, ATP binding cassette subfamily B member" Q03518 6 32845209-32853816 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 126.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009516, HPA072354" Approved Approved "Endoplasmic reticulum,Centriolar satellite" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Centriolar satellite" "CAB009516: AB_2303048, HPA072354: AB_2686513" "unprognostic (3.59e-2)" "unprognostic (1.06e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (6.16e-3)" "unprognostic (2.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (3.02e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (6.58e-5)" "unprognostic (2.07e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-2)" "unprognostic (2.21e-2)" 28.4 24.9 16.1 50.1 16.2 13.7 20.7 15.8 20.3 21.6 16.2 30.3 36.0 20.5 2.5 31.6 17.8 12.7 25.4 14.7 16.2 21.8 19.3 52.7 50.0 24.0 16.1 12.1 14.5 7.0 11.6 12.1 21.2 21.9 12.5 1.7 25.9 7.0 16.3 51.2 42.6 11.5 18.6 73.0 33.4 11.5 19.4 25.5 17.0 7.4 21.3 23.9 24.4 17.4 22.9 13.7 0.1 16.1 8.8 11.4 126.2 8.1 34.3 59.3 86.5 2.0 27.3 41.8 25.0 12.6 48.9 45.8 4.5 20.6 5.3 81.0 6.1 26.5 4.1 10.8 42.3 0.1 17.5 15.0 17.9 17.1 10.4 8.6 15.4 8.4 1.9 55.0 10.6 10.5 17.7 27.4 0.8 3.1 11.1 47.6 5.2 32.8 25.0 10.5 0.2 1.2 6.7 38.0 33.4 1.7 30.9 37.4 9.7 21.5 8.1 53.1 11.4 59.9 82.6 12.6 16.6 16.6 16.4 176.8 99.5 270.1 155.8 101.6 133.8 137.3 125.2 153.7 95.0 107.5 120.9 124.6 295.6 132.9 94.6 94.8 213.8 221.2 16.1 16.2 15.8 20.3 14.7 16.2 24.0 16.1 21.2 18.6 19.4 17.4 72.1 25.6 24.0 9.1 62.1 74.7 47.1 54.5 27.3 4.8 21.5 15.9 7.3 24.3 33.1 5.5 0.0 5.6 108.0 78.8 5.9 81.6 0.5 31.3 39.3 63.6 16.8 12.6 1.1 75.3 95.0 26.9 42.8 77.9 26.6 13.8 27.1 11.1 45.9 15.2 1.9 55.9 57.0 31.9 90.6 0.3 13.1 43.9 23.2 16.9 115.9 25.1 149.3 12.1 3.6 91.3 38.8 10.5 84.8 70.2 84.6 6.9 29.4 2.8 6.6 18.1 27.8 1.0 1.3 20.4 76.4 4.8 92.3 18.2 54.5 52.1 TBC1D12 KIAA0608 ENSG00000108239 "TBC1 domain family member 12" O60347 10 94402541-94536332 "Cancer-related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.1" "Cell type enhanced" "Detected in many" "Microglial cells: 110.5;Oligodendrocytes: 397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038277, HPA038645" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "HPA038277: AB_10672584, HPA038645: AB_10672650" "unprognostic (7.23e-3)" "unprognostic (1.58e-2)" "prognostic favorable (1.79e-5)" "unprognostic (7.83e-2)" "unprognostic (1.76e-1)" "unprognostic (4.91e-2)" "unprognostic (1.21e-2)" "unprognostic (7.34e-2)" "unprognostic (6.56e-2)" "unprognostic (9.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.59e-1)" "unprognostic (2.27e-2)" "unprognostic (9.43e-2)" "unprognostic (3.71e-1)" "unprognostic (1.29e-1)" "unprognostic (1.12e-1)" 5.8 3.6 13.5 3.1 26.5 1.1 5.6 28.3 16.0 4.6 8.2 6.1 4.5 4.1 2.8 3.3 3.8 3.6 3.8 12.4 17.8 4.0 3.7 4.7 2.5 40.2 26.7 3.9 4.6 13.3 2.6 5.7 35.8 4.1 6.8 7.0 3.2 4.3 4.1 4.9 5.1 4.3 25.1 4.9 3.6 8.4 23.0 1.3 3.3 4.1 2.6 4.6 4.1 46.1 7.3 3.2 4.1 6.1 5.6 6.8 5.4 4.6 9.5 5.1 4.7 12.8 3.1 0.0 2.7 6.8 4.9 4.0 4.9 3.4 6.5 0.0 5.7 2.3 2.9 4.1 4.2 0.0 1.8 4.6 4.3 5.3 6.9 8.6 5.5 0.0 3.4 7.4 8.2 4.0 0.0 0.0 1.3 5.2 3.3 0.0 5.3 3.9 4.6 3.2 1.7 4.1 4.6 4.0 3.9 3.7 8.6 4.4 5.4 3.5 4.8 5.7 3.7 5.1 5.3 0.0 3.5 0.0 1.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 26.5 28.3 16.0 12.4 17.8 40.2 26.7 35.8 25.1 23.0 46.1 11.0 9.6 5.3 34.9 7.6 19.5 6.5 2.9 10.8 17.5 10.6 9.1 6.5 4.3 4.3 9.2 10.4 19.4 0.6 18.1 0.0 5.8 22.6 7.6 9.5 13.7 8.4 5.2 46.8 5.1 13.4 23.8 13.7 10.3 5.7 3.5 8.9 4.8 19.1 8.4 66.7 8.7 4.1 23.6 25.9 9.2 8.4 20.9 16.0 110.5 11.7 8.9 1.0 60.8 397.2 7.6 13.2 10.5 12.0 11.7 11.7 5.9 4.0 28.0 13.1 11.7 12.0 64.3 13.5 11.4 19.2 24.4 1.5 6.3 11.8 10.3 TBL1XR1 "C21, DC42, FLJ12894, IRA1, TBLR1" ENSG00000177565 "TBL1X receptor 1" Q9BZK7 3 177019340-177228000 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 280.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019182 Supported Approved Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA019182: AB_1857800" "unprognostic (4.11e-2)" "unprognostic (3.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.27e-3)" "prognostic favorable (5.16e-5)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.08e-7)" "unprognostic (3.75e-1)" "unprognostic (4.84e-2)" "unprognostic (3.04e-1)" "unprognostic (3.13e-3)" "unprognostic (2.50e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (5.83e-2)" "unprognostic (1.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" 18.8 20.3 7.2 24.4 12.7 30.2 21.7 13.9 11.8 24.9 8.5 31.0 24.6 16.9 9.2 21.2 22.4 23.2 32.6 16.0 3.3 22.3 24.5 19.6 31.3 8.1 8.5 20.9 12.1 27.3 2.9 21.0 4.9 25.6 24.4 42.7 16.1 14.8 12.9 17.1 18.7 19.4 8.6 22.9 22.3 19.1 8.4 45.5 47.1 25.3 36.3 25.3 10.3 15.0 96.8 41.2 61.1 39.7 56.2 65.8 44.2 26.1 52.3 30.3 36.3 48.9 76.2 98.9 132.9 43.6 58.4 61.2 42.9 63.2 58.7 97.5 14.5 56.2 66.8 30.3 49.7 91.0 29.6 95.3 35.9 37.3 90.6 53.8 48.5 68.5 44.8 189.9 42.8 31.0 81.7 14.0 38.1 59.8 32.2 53.9 72.6 124.6 33.1 119.5 24.8 38.7 43.3 35.9 49.8 37.3 113.0 74.3 60.5 48.9 35.3 28.8 65.6 89.8 117.6 280.7 32.9 66.2 56.1 14.3 3.7 3.8 5.6 6.2 5.9 7.5 6.9 7.3 4.6 7.3 5.9 7.4 12.9 7.4 5.5 12.4 8.3 5.3 7.2 12.7 13.9 11.8 16.0 3.3 8.1 8.5 4.9 8.6 8.4 15.0 55.1 73.7 60.7 128.0 56.5 91.5 55.1 90.6 62.0 113.6 69.2 42.2 101.9 47.1 80.3 104.8 125.1 28.9 70.0 84.7 29.4 52.2 7.4 90.9 59.0 65.5 85.3 60.4 228.9 43.8 35.1 81.8 44.4 134.5 25.3 65.9 48.5 66.6 37.8 116.1 167.6 72.6 59.0 91.1 75.0 9.0 64.0 69.4 65.8 184.6 55.8 47.6 41.2 241.8 269.4 66.7 43.7 73.0 75.1 144.9 41.5 67.3 83.9 81.6 46.0 76.3 54.4 12.9 61.4 88.1 111.8 27.5 66.0 41.6 84.6 83.6 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 178.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 613.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favorable (3.28e-4)" 13.3 178.4 5.1 2.5 4.7 0.0 34.1 3.9 5.7 37.5 2.9 7.4 37.6 32.8 44.6 2.8 24.0 4.5 13.2 3.8 14.9 12.9 31.3 32.8 1.4 4.6 4.4 44.2 2.9 1.0 12.9 41.3 4.8 80.4 3.7 1.8 18.9 53.2 10.4 14.9 30.3 10.0 3.8 7.0 6.0 1.3 6.6 1.3 50.0 16.5 1.7 53.9 34.2 3.7 2.4 18.2 0.0 0.0 26.1 35.6 40.1 103.0 97.3 39.0 38.3 16.3 4.4 0.0 1.6 18.0 2.4 4.7 8.4 3.6 47.7 0.0 12.3 0.0 4.8 48.1 8.4 0.0 0.0 16.0 2.4 13.1 26.8 0.0 0.5 0.0 3.8 0.0 3.4 1.6 0.0 0.5 0.2 53.0 5.4 0.0 0.0 2.6 0.0 129.3 6.6 19.4 14.6 6.6 3.6 44.6 5.1 0.2 0.0 11.9 7.7 6.8 33.9 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.7 3.9 5.7 3.8 14.9 4.6 4.4 4.8 3.8 6.6 3.7 48.9 0.0 1.9 0.3 1.8 9.8 85.2 5.8 7.4 14.3 110.3 80.5 12.5 0.0 1.1 35.0 4.2 60.7 0.7 12.0 0.0 0.6 1.5 3.3 144.7 38.6 4.9 0.0 0.0 0.0 7.0 41.3 5.1 3.8 0.0 3.9 1.1 40.2 6.1 1.7 0.0 23.9 4.1 0.9 4.6 2.8 5.3 2.9 3.6 14.0 0.0 1.9 0.0 0.0 0.0 0.3 22.4 6.0 0.0 72.4 37.9 0.1 0.4 2.0 39.5 27.2 58.2 0.1 3.8 3.2 9.8 613.9 2.0 112.0 12.1 69.1 TCEA1 "GTF2S, SII, TCEA, TF2S, TFIIS" ENSG00000187735 "Transcription elongation factor A1" P23193 8 53966552-54022456 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043786 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA043786: AB_10959468" "unprognostic (5.35e-2)" "unprognostic (9.90e-2)" "unprognostic (2.39e-1)" "unprognostic (2.11e-3)" "unprognostic (3.34e-2)" "unprognostic (1.17e-1)" "unprognostic (3.72e-2)" "unprognostic (1.77e-1)" "unprognostic (4.14e-2)" "unprognostic (1.00e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.75e-5)" "unprognostic (3.80e-3)" "unprognostic (1.10e-1)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" 52.7 46.0 44.1 56.5 47.5 81.2 62.2 44.7 58.3 55.3 42.5 49.7 47.1 55.6 45.8 53.9 52.4 42.6 35.9 42.0 46.0 59.8 90.4 46.7 98.3 47.2 44.6 61.9 68.4 80.0 28.2 49.3 47.0 59.0 50.7 49.0 56.5 54.2 42.0 49.8 46.9 52.4 47.5 49.5 52.2 36.8 44.2 72.4 124.2 41.7 112.6 54.6 41.4 55.1 161.3 157.9 138.1 145.7 99.3 121.8 100.9 122.1 147.3 143.5 160.2 91.4 131.0 392.5 136.9 147.0 152.5 120.9 182.3 116.6 212.9 225.0 88.5 293.6 71.5 139.5 309.7 116.8 122.7 88.5 308.1 137.4 606.2 121.3 128.2 132.9 191.1 334.0 135.5 75.6 245.8 83.3 229.1 265.0 47.1 185.1 48.2 72.5 204.0 107.0 129.9 95.5 101.9 91.0 356.3 132.2 129.6 132.6 110.6 106.1 96.3 120.6 114.5 201.1 134.4 260.9 184.9 133.2 152.1 82.3 64.1 78.7 103.9 63.1 98.3 213.8 107.0 96.7 81.8 174.1 93.9 99.3 23.1 97.5 60.6 116.7 153.0 73.5 44.1 47.5 44.7 58.3 42.0 46.0 47.2 44.6 47.0 47.5 44.2 55.1 94.7 89.8 106.2 24.2 253.2 135.5 128.3 98.9 257.2 77.0 129.2 124.3 23.9 82.9 109.4 99.3 89.6 115.5 143.8 61.0 168.3 121.0 86.4 126.9 145.4 92.5 87.2 330.7 17.7 109.9 125.1 118.8 111.6 124.4 98.7 75.7 66.4 160.7 87.7 57.2 20.1 96.6 118.0 89.5 134.2 191.0 134.8 124.2 117.4 17.8 132.5 166.0 170.0 22.1 29.7 121.1 71.6 132.8 341.1 146.0 72.2 207.6 110.6 104.5 78.9 102.6 130.4 94.9 103.1 237.2 150.6 112.1 154.8 108.5 88.1 148.6 TCF12 "bHLHb20, HEB, HsT17266, HTF4, p64" ENSG00000140262 "Transcription factor 12" Q99081 15 56918623-57299281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 319.8;Microglial cells: 440.3;Oligodendrocyte precursor cells: 618.3;Oligodendrocytes: 1512.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004432, HPA065827" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear speckles" "CAB004432: AB_671267, HPA065827: AB_2685564" "unprognostic (1.19e-1)" "unprognostic (1.11e-1)" "unprognostic (8.26e-2)" "unprognostic (1.65e-1)" "unprognostic (2.07e-3)" "unprognostic (1.11e-1)" "unprognostic (6.63e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (7.83e-2)" "unprognostic (7.26e-3)" "unprognostic (5.57e-3)" "prognostic unfavorable (5.24e-5)" "unprognostic (2.03e-1)" "unprognostic (2.93e-1)" "unprognostic (3.15e-2)" "unprognostic (1.41e-1)" 26.1 21.5 29.2 23.4 45.5 21.2 29.5 37.1 34.0 75.6 17.2 26.7 28.4 47.9 24.3 26.6 46.3 37.1 21.8 30.5 32.6 28.4 25.0 28.9 26.0 43.1 39.3 43.3 19.7 44.0 11.5 33.4 38.3 32.0 30.3 29.4 23.3 28.3 20.5 21.3 28.4 44.1 34.5 25.0 25.5 27.4 35.5 133.0 29.0 26.6 28.1 31.2 22.4 55.7 25.4 50.8 204.5 70.6 90.0 79.0 36.1 52.2 89.6 45.1 58.9 34.0 20.3 35.5 42.3 78.3 33.4 30.4 84.3 37.3 56.7 47.5 29.8 71.7 52.7 40.4 62.4 46.1 36.1 69.4 66.2 42.9 112.2 60.1 81.0 163.0 81.7 46.8 61.8 9.5 109.4 25.0 57.5 26.4 20.9 143.2 234.9 33.9 61.5 53.1 43.6 121.2 58.7 21.0 52.0 65.3 33.6 93.9 63.2 75.5 57.5 32.2 78.2 24.6 49.7 59.4 40.8 86.3 90.9 27.4 13.8 11.3 17.4 17.9 14.3 13.4 14.0 16.5 20.0 14.7 16.2 14.8 1.5 16.8 26.3 8.4 23.0 14.1 29.2 45.5 37.1 34.0 30.5 32.6 43.1 39.3 38.3 34.5 35.5 55.7 35.5 54.5 19.6 212.9 37.7 26.6 20.6 14.2 44.9 13.8 24.0 20.4 19.3 14.3 21.2 16.5 35.5 10.4 20.6 17.0 13.7 16.0 23.7 25.9 148.0 38.2 9.0 34.9 117.7 11.8 15.5 42.3 52.0 33.3 23.4 26.9 25.7 18.2 27.5 13.5 319.8 16.8 10.2 38.1 30.0 19.9 25.7 33.0 14.2 440.3 17.4 29.0 18.6 618.3 1512.7 15.9 18.4 34.6 29.1 23.4 20.0 15.3 15.9 23.3 46.0 39.9 36.5 22.2 15.0 33.6 33.8 13.0 28.4 16.5 20.1 18.2 TCF3 "bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, p75, VDIR" ENSG00000071564 "Transcription factor 3" P15923 19 1609290-1652615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 467.3;U-698: 597.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018351, HPA049808, HPA062476" Approved Enhanced Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "CAB018351: AB_675504, HPA049808: AB_2680892, HPA062476: AB_2684775" "unprognostic (8.82e-2)" "unprognostic (4.74e-2)" "unprognostic (1.26e-2)" "unprognostic (1.25e-1)" "unprognostic (1.91e-2)" "unprognostic (8.25e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.07e-2)" "unprognostic (7.99e-2)" "unprognostic (2.35e-1)" "unprognostic (2.42e-1)" "unprognostic (9.29e-3)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.87e-3)" "unprognostic (1.88e-1)" "unprognostic (3.07e-1)" "unprognostic (8.05e-2)" 23.8 17.9 20.7 49.2 20.0 72.8 26.1 18.1 22.7 33.4 21.9 32.3 35.5 29.6 16.2 28.2 25.5 19.8 22.8 19.1 17.8 27.2 18.9 25.9 86.6 22.0 19.3 35.1 28.4 10.2 26.2 17.9 20.4 27.3 18.7 11.0 26.4 12.0 19.5 32.9 48.0 14.4 18.3 62.5 27.3 74.8 20.3 68.4 31.6 12.5 61.0 27.4 27.4 21.8 83.6 48.6 146.4 139.8 18.6 49.6 50.4 51.9 48.0 67.8 60.6 89.8 68.7 421.7 53.5 50.1 12.7 98.4 87.9 69.2 42.8 253.7 52.4 43.2 71.2 115.2 44.8 105.7 56.8 34.0 75.1 52.4 39.2 64.0 82.5 176.1 163.8 146.6 46.0 158.2 301.1 107.8 187.1 65.1 49.2 467.3 61.7 104.3 46.5 78.5 119.3 175.7 50.1 55.9 70.8 53.0 63.8 191.7 103.2 87.1 90.5 116.0 94.1 353.5 173.5 597.2 63.1 140.3 80.1 3.3 1.2 1.0 3.6 1.5 3.6 10.0 2.1 3.1 2.8 10.6 2.8 4.3 0.4 2.8 3.2 12.9 2.2 1.7 20.7 20.0 18.1 22.7 19.1 17.8 22.0 19.3 20.4 18.3 20.3 21.8 17.3 6.4 9.1 14.7 33.9 13.9 5.3 10.0 4.6 12.3 16.6 16.1 10.7 4.3 10.8 1.8 27.1 4.3 26.5 14.7 1.9 11.4 8.6 9.9 20.4 13.5 16.2 32.2 3.9 6.9 8.9 12.3 14.8 16.6 7.0 27.8 9.7 4.8 7.7 5.0 5.6 16.5 16.2 8.9 12.3 5.2 13.7 9.4 10.6 6.5 8.1 9.2 10.3 3.0 7.3 17.6 13.3 10.1 31.1 13.0 16.4 6.3 2.9 13.8 19.7 8.2 16.9 5.5 46.2 9.0 13.2 2.9 12.5 10.4 20.1 8.5 TCF7 TCF-1 ENSG00000081059 "Transcription factor 7" P36402 5 134114681-134151865 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "lymphoid tissue: 604.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 73.0;T-cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 28.8;memory CD4 T-cell: 49.7;memory CD8 T-cell: 29.0;naive CD4 T-cell: 97.2;naive CD8 T-cell: 62.3;NK-cell: 43.0" "Group enriched" "Detected in many" 20 "NK-cells: 43.0;T-cells: 97.2" "Cell line enriched" "Detected in many" 6 "MOLT-4: 1324.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019403, HPA058863, HPA070505" Enhanced Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "CAB019403: AB_2199302, HPA058863: AB_2683837, HPA070505: AB_2686275" "unprognostic (3.63e-3)" "unprognostic (1.98e-3)" "unprognostic (1.03e-1)" "unprognostic (5.08e-3)" "unprognostic (1.70e-1)" "unprognostic (6.74e-2)" "unprognostic (1.12e-1)" "unprognostic (6.38e-2)" "unprognostic (2.31e-1)" "unprognostic (1.65e-1)" "unprognostic (5.35e-2)" "unprognostic (2.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.50e-2)" "unprognostic (2.33e-2)" "unprognostic (1.90e-1)" "unprognostic (4.10e-2)" 4.1 5.3 2.0 56.4 1.8 16.4 4.0 1.8 1.9 3.2 21.3 5.8 16.0 3.9 41.5 3.5 43.1 6.2 2.4 3.1 1.5 4.0 5.8 5.6 94.4 5.9 2.7 1.8 9.4 2.1 6.4 3.5 2.2 5.0 6.8 1.5 8.0 3.5 1.4 4.3 20.4 1.8 3.8 34.6 11.0 3.4 2.1 604.3 6.3 1.0 70.0 9.8 2.0 2.6 0.2 7.8 8.2 29.2 3.9 16.2 11.4 2.2 4.4 0.7 0.8 61.6 19.3 0.4 14.0 13.4 32.3 1.0 13.1 3.1 0.6 3.0 12.2 0.2 7.4 46.4 0.4 0.4 1.6 1.1 0.1 12.6 0.7 5.7 1.8 218.2 7.9 0.3 1.3 0.7 1324.2 1.4 9.0 19.2 10.4 1.6 0.0 1.4 3.0 1.4 3.4 25.1 6.0 1.8 1.6 6.4 1.6 7.3 1.9 81.2 0.5 37.0 2.8 1.3 0.1 0.4 42.7 0.5 4.1 2.2 0.3 3.2 12.3 0.2 28.8 3.5 49.7 29.0 0.2 1.4 97.2 62.3 1.9 43.0 0.2 0.5 6.5 21.8 2.0 1.8 1.8 1.9 3.1 1.5 5.9 2.7 2.2 3.8 2.1 2.6 6.0 3.2 1.9 4.6 27.3 15.7 27.9 6.9 2.8 28.6 14.5 14.9 3.1 10.0 2.9 3.7 73.0 21.6 47.4 18.4 0.0 6.1 3.8 57.6 30.4 9.6 12.6 5.3 2.4 9.9 30.5 11.7 6.6 35.8 20.3 12.1 6.8 3.0 7.1 10.1 2.0 17.0 6.1 9.7 20.0 2.3 6.2 8.7 10.6 1.0 17.1 12.4 41.2 3.5 4.1 23.6 18.5 4.5 9.3 24.6 50.8 1.4 2.5 58.4 0.0 61.4 16.1 4.0 11.0 3.3 11.4 30.0 108.3 8.6 24.1 14.9 TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 244.9" "Cell type enhanced" "Detected in many" "Astrocytes: 264.8;Distal enterocytes: 260.0;Extravillous trophoblasts: 231.4;Paneth cells: 211.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 244.9" "Group enriched" "Detected in many" 10 "intermediate monocyte: 28.9;non-classical monocyte: 86.6" "Lineage enriched" "Detected in many" 14 "monocytes: 86.6" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 5 "midbrain: 146.8;pons: 97.8;thalamus: 164.3" "CAB013535, HPA038800" Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: AB_2533167, HPA038800: " "unprognostic (1.79e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.31e-2)" "unprognostic (4.59e-3)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-2)" "unprognostic (5.09e-1)" "unprognostic (7.10e-2)" "unprognostic (6.10e-3)" "unprognostic (3.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (7.36e-3)" 28.1 9.4 47.4 8.6 6.3 7.6 25.0 0.2 12.1 18.9 1.0 22.9 20.4 25.1 6.7 9.9 18.1 9.4 11.3 4.3 46.9 9.9 22.4 13.9 5.4 5.1 98.0 22.9 12.4 11.1 9.6 17.7 1.7 12.3 21.3 4.6 14.5 13.1 8.4 17.2 19.3 16.4 1.6 22.2 23.3 7.6 244.9 5.8 12.9 6.9 3.7 13.8 14.3 3.2 15.0 37.8 40.7 39.6 20.8 13.7 48.5 10.3 20.0 7.1 8.5 24.9 45.3 0.1 11.3 19.4 9.6 10.5 14.0 17.6 9.1 1.7 13.1 10.4 25.2 23.6 22.0 4.2 3.7 24.4 6.3 11.0 18.2 29.7 12.0 8.8 11.0 0.7 8.2 28.0 6.7 2.5 29.2 16.6 21.6 19.0 29.8 6.9 15.2 20.4 0.8 12.4 15.7 15.4 17.0 31.5 10.0 2.2 27.9 6.8 18.7 16.9 21.3 2.6 0.3 0.4 6.5 8.7 14.9 0.4 4.5 0.4 1.5 28.9 0.9 0.0 0.4 1.2 4.1 0.0 0.4 0.6 6.0 0.0 86.6 0.2 0.0 3.5 47.4 6.3 0.2 12.1 4.3 46.9 5.1 98.0 1.7 1.6 244.9 3.2 62.0 22.4 26.5 264.8 3.3 42.6 27.3 35.8 64.9 2.8 53.0 54.9 13.6 52.9 35.5 40.5 6.2 44.2 9.1 260.0 11.7 39.3 8.8 40.1 140.6 46.1 19.8 4.8 35.1 43.6 231.4 90.8 90.2 64.2 0.0 37.6 52.8 74.2 17.5 5.0 16.6 87.7 16.2 99.9 20.6 5.0 59.0 54.6 32.0 107.7 22.4 34.4 5.2 192.5 34.9 59.0 211.1 48.5 6.0 38.4 75.3 16.2 26.8 6.1 92.1 37.3 51.3 9.4 28.9 61.1 39.8 28.5 6.7 13.1 73.9 49.0 TCL1A TCL1 ENSG00000100721 "TCL1 family AKT coactivator A" P56279 14 95709947-95714196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 267.6" "Group enriched" "Detected in some" 4 "B-cells: 282.5;dendritic cells: 210.3" "Cancer enriched" "Detected in many" 18 "testis cancer: 64.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 296 "memory B-cell: 874.7;naive B-cell: 2160.3;plasmacytoid DC: 1099.9" "Group enriched" "Detected in all" 350 "B-cells: 2160.3;dendritic cells: 1099.9" "Group enriched" "Detected in some" 142 "Daudi: 459.4;REH: 599.4;U-698: 616.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004045, HPA016604" Enhanced Enhanced "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB004045: AB_2179419, HPA016604: AB_1857859" "unprognostic (1.27e-3)" "unprognostic (3.12e-4)" "unprognostic (2.61e-4)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (4.75e-4)" "unprognostic (7.70e-2)" "unprognostic (9.67e-3)" "unprognostic (1.03e-1)" "unprognostic (3.35e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-2)" "unprognostic (2.64e-2)" "unprognostic (1.87e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (4.55e-1)" 1.0 0.1 0.1 34.4 0.1 20.3 0.2 0.1 0.1 0.1 0.0 2.4 0.8 0.8 0.6 0.5 0.1 3.6 0.6 0.1 0.1 0.4 0.4 1.0 267.6 0.1 0.1 0.1 0.3 0.0 0.0 0.8 0.2 0.3 2.0 0.0 4.0 0.0 0.1 0.4 14.2 0.3 0.0 56.7 3.4 7.7 0.1 19.1 1.1 0.0 216.0 2.7 0.1 0.3 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 459.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.6 0.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 599.4 0.3 0.8 0.0 0.0 0.2 0.2 0.4 0.7 0.1 0.3 0.1 1.0 1.0 0.2 2.8 0.6 0.2 0.5 3.9 616.2 0.2 0.1 0.1 4.6 1.4 1.8 0.5 0.5 1.3 874.7 0.9 0.4 2.2 2160.3 1.5 0.5 3.3 1.3 1.6 1099.9 1.2 92.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 1.3 0.0 282.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 210.3 0.6 0.0 0.0 0.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.2 0.0 0.3 0.0 0.9 0.6 2.8 0.0 0.0 2.7 0.0 3.1 0.0 0.0 0.0 0.2 0.4 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 28.7 60.2 0.0 0.0 0.0 2.7 0.0 0.3 0.0 TCP11L2 MGC40368 ENSG00000166046 "T-complex 11 like 2" Q8N4U5 12 106301929-106347003 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 98.8;choroid plexus: 79.4" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 67.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.0" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039483, HPA042188" Uncertain Supported "Nuclear speckles" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "HPA039483: AB_10795291, HPA042188: AB_10794415" "unprognostic (1.41e-1)" "unprognostic (3.17e-1)" "unprognostic (1.24e-1)" "unprognostic (8.15e-2)" "unprognostic (1.97e-1)" "prognostic favorable (9.52e-4)" "unprognostic (3.87e-3)" "unprognostic (2.43e-1)" "unprognostic (2.11e-1)" "unprognostic (9.05e-3)" "unprognostic (5.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-2)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (5.02e-2)" "unprognostic (3.67e-1)" 11.5 8.8 16.4 7.9 43.0 30.3 10.3 32.6 24.5 9.2 79.4 7.7 7.5 10.0 4.2 22.9 13.1 9.5 22.6 12.9 22.4 6.7 6.5 16.7 10.2 46.6 33.2 9.0 6.0 10.2 4.8 14.5 43.3 6.7 9.0 10.3 12.1 6.5 17.9 13.9 9.8 8.2 28.4 11.7 12.1 10.6 30.8 13.6 11.6 23.0 16.8 8.5 9.3 98.8 3.3 8.1 1.1 2.3 10.6 12.2 5.0 2.1 10.2 1.3 3.2 1.3 4.3 1.1 3.2 8.1 3.0 15.2 1.0 4.5 2.3 1.7 3.3 0.7 3.4 5.1 10.4 0.3 2.1 15.4 10.2 1.6 7.6 25.1 7.5 5.9 2.0 1.5 1.9 2.4 2.0 1.7 1.4 4.4 5.0 1.0 0.3 3.8 10.1 15.2 5.0 3.6 5.5 1.7 6.0 8.4 4.6 0.3 5.7 1.9 1.6 2.9 0.5 10.0 0.8 3.8 5.3 0.3 1.0 29.6 6.9 11.0 4.8 3.1 3.6 12.4 9.9 5.4 1.7 10.6 12.2 8.3 67.0 4.3 5.3 1.2 12.3 3.8 16.4 43.0 32.6 24.5 12.9 22.4 46.6 33.2 43.3 28.4 30.8 98.8 12.6 12.8 14.4 15.0 23.1 1.1 3.4 4.4 5.7 8.1 3.5 5.5 10.5 0.0 8.6 3.7 22.9 1.5 13.4 4.2 1.9 3.6 6.3 28.6 7.3 12.1 4.2 33.7 7.7 2.6 0.8 10.5 11.2 20.5 2.5 4.3 6.1 1.5 1.2 21.9 23.9 5.0 2.0 3.1 2.0 4.5 5.9 5.2 3.6 12.2 8.0 3.1 10.3 9.0 111.0 3.7 4.8 2.6 9.9 4.0 5.9 1.2 16.7 13.4 13.1 11.8 7.2 4.3 3.0 6.3 2.6 15.1 12.4 8.0 1.2 8.7 TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late spermatids: 89.0;Spermatocytes: 103.7" "Cancer enhanced" "Detected in many" "testis cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.0;TIME: 1.4" "Not detected" "Not detected" HPA054327 Approved Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA054327: AB_2682452" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.33e-3)" "unprognostic (9.69e-3)" "unprognostic (5.80e-3)" "unprognostic (2.99e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (8.04e-5)" "unprognostic (1.62e-1)" 11.1 4.5 3.7 0.5 3.7 0.1 6.8 3.1 3.7 5.1 3.3 2.8 0.7 4.2 2.3 2.4 6.5 1.6 7.6 3.3 3.2 3.5 4.5 8.1 0.8 3.2 3.5 10.1 0.9 0.9 2.6 1.7 3.3 3.9 1.3 0.1 1.8 1.2 1.9 2.3 3.5 1.8 3.2 8.9 1.9 55.6 3.7 0.5 11.0 1.4 0.4 3.9 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.7 3.1 3.7 3.3 3.2 3.2 3.5 3.3 3.2 3.7 3.1 10.0 3.2 6.7 4.9 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.5 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.8 0.0 0.1 8.2 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 1.3 0.7 6.1 0.4 0.4 0.0 0.5 0.0 0.0 4.0 2.1 89.0 2.5 1.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 103.7 16.5 0.1 0.3 0.0 0.0 0.1 0.0 0.0 TDRD6 "bA446F17.4, CT41.2, NY-CO-45, SPATA36" ENSG00000180113 "Tudor domain containing 6" O60522 6 46687875-46704319 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.3" "Group enriched" "Detected in many" 4 "Early spermatids: 224.8;Spermatocytes: 82.7" "Cancer enhanced" "Detected in some" "prostate cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075923, HPA077353" Enhanced Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" Vesicles "HPA075923: , HPA077353: " "unprognostic (2.01e-1)" "unprognostic (7.41e-3)" "unprognostic (7.25e-3)" "unprognostic (3.88e-2)" "unprognostic (3.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (7.97e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-3)" "unprognostic (2.20e-1)" "unprognostic (2.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.00e-1)" "unprognostic (2.16e-2)" "unprognostic (4.38e-3)" 0.7 1.7 3.3 3.0 5.1 0.2 0.8 7.8 5.4 1.2 1.8 1.0 0.7 0.9 3.4 0.6 0.8 2.2 1.6 4.1 2.6 2.1 2.5 0.7 4.0 3.9 3.2 1.1 1.1 0.4 3.0 1.6 4.1 2.0 0.3 8.9 1.3 0.6 2.3 3.5 0.7 0.4 2.7 2.5 0.8 30.3 3.7 0.0 5.6 0.1 0.1 1.1 0.8 4.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.1 7.8 5.4 4.1 2.6 3.9 3.2 4.1 2.7 3.7 4.0 0.8 9.6 0.5 3.9 0.0 0.5 0.4 0.1 1.2 11.3 0.4 0.8 3.4 0.0 3.8 7.3 6.2 0.0 0.0 0.0 1.9 0.3 224.8 1.0 2.2 1.2 4.2 0.0 13.6 0.2 0.0 1.0 0.0 0.7 0.0 0.4 0.7 3.0 0.1 5.0 14.7 0.3 0.0 0.3 0.0 33.8 4.1 0.5 3.6 6.5 0.0 1.1 0.0 14.6 17.8 0.1 0.0 4.5 0.0 0.6 0.4 0.4 0.2 7.5 13.1 3.0 0.5 82.7 34.7 0.0 1.6 0.0 0.0 1.4 0.5 0.2 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TENT5C "FAM46C, FLJ20202" ENSG00000183508 "Terminal nucleotidyltransferase 5C" Q5VWP2 1 117606048-117628389 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Nucleotidyltransferase, RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 89.1" "Cell type enhanced" "Detected in some" "B-cells: 41.8;Breast glandular cells: 34.0;Breast myoepithelial cells: 43.2;dendritic cells: 104.5;Plasma cells: 47.7;T-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 29.3" "Group enriched" "Detected in many" 17 "B-cells: 13.3;granulocytes: 29.3;T-cells: 13.7" "Cell line enhanced" "Detected in many" "Karpas-707: 296.2;RPMI-8226: 185.5;U-266/70: 81.7;U-266/84: 72.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054049 Uncertain Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA054049: AB_2682356" "unprognostic (3.76e-2)" "unprognostic (3.85e-3)" "unprognostic (3.24e-3)" "prognostic favorable (3.75e-5)" "unprognostic (1.17e-1)" "unprognostic (1.55e-3)" "unprognostic (3.29e-1)" "unprognostic (2.88e-2)" "unprognostic (5.75e-2)" "unprognostic (1.36e-3)" "unprognostic (9.41e-3)" "unprognostic (3.91e-2)" "prognostic favorable (2.77e-5)" "unprognostic (6.26e-2)" "unprognostic (3.16e-2)" "unprognostic (3.08e-2)" "unprognostic (1.10e-2)" 2.8 2.4 0.9 17.0 1.0 89.1 11.6 1.1 1.6 10.9 27.4 23.8 16.0 3.2 19.1 3.6 4.8 7.8 6.9 1.4 0.9 7.5 10.3 10.5 18.8 1.6 1.6 9.0 46.8 11.2 2.6 3.8 1.1 6.6 24.8 0.1 25.8 4.1 29.4 1.2 13.0 2.9 1.9 21.7 30.2 43.5 1.0 6.2 14.3 10.9 37.3 14.1 1.9 1.3 0.2 0.1 0.1 1.3 0.1 0.0 1.3 0.6 26.9 0.5 0.2 1.7 0.2 4.9 0.3 0.8 0.3 0.3 0.1 0.5 0.2 17.6 1.6 37.9 0.2 0.0 0.1 22.4 46.8 0.0 0.1 0.4 0.0 0.1 0.1 10.0 5.2 296.2 0.0 3.8 0.1 22.8 3.8 4.5 2.4 0.1 0.1 185.5 0.3 3.7 2.2 0.2 1.7 2.4 1.8 0.6 1.9 0.2 0.5 0.3 2.1 0.1 0.4 81.7 72.8 1.9 1.7 8.1 2.4 29.3 0.0 15.9 3.4 0.0 3.1 13.3 3.3 4.4 0.1 10.4 0.4 1.9 1.6 1.1 0.0 0.3 13.7 2.9 0.9 1.0 1.1 1.6 1.4 0.9 1.6 1.6 1.1 1.9 1.0 1.3 17.0 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 34.0 43.2 0.0 0.0 0.0 1.8 0.0 1.9 104.5 0.0 11.7 0.8 0.0 8.3 5.4 2.9 0.0 0.0 0.0 5.2 2.2 3.2 0.0 13.7 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 47.7 0.0 0.0 9.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 2.2 48.4 1.0 0.0 0.0 TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Intestinal goblet cells: 1.0;Plasma cells: 2.8;Spermatocytes: 1.5;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 438.0;fHDF/TERT166: 429.4;HBEC3-KT: 929.2;hTEC/SVTERT24-B: 560.1;LHCN-M2: 252.2;TIME: 799.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: AB_2682554, HPA065897: AB_2685576" "unprognostic (1.21e-2)" "unprognostic (2.88e-2)" "unprognostic (1.24e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-3)" "unprognostic (6.42e-3)" "unprognostic (1.85e-2)" "unprognostic (2.21e-1)" "unprognostic (6.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.59e-1)" "unprognostic (9.16e-4)" "unprognostic (8.84e-11)" "unprognostic (1.92e-1)" "unprognostic (2.15e-1)" "unprognostic (3.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 213.2 438.0 3.2 0.0 173.9 31.7 59.4 0.3 0.1 3.0 0.2 429.4 0.1 0.1 1.0 929.2 29.1 0.0 1.7 0.1 0.0 0.4 0.1 0.5 1.2 0.0 22.9 560.1 6.8 1.3 1.5 1.8 2.9 0.2 252.2 0.4 0.2 9.4 2.9 0.1 1.3 2.1 0.0 5.4 23.9 0.5 0.2 2.1 0.1 0.0 0.2 0.0 0.1 0.3 799.9 0.0 0.0 0.0 0.0 0.9 0.5 0.7 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 TET1 "bA119F7.1, CXXC6, KIAA1676, LCX" ENSG00000138336 "Tet methylcytosine dioxygenase 1" Q8NFU7 10 68560337-68694487 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9" "Cell type enhanced" "Detected in many" "Astrocytes: 54.5;Extravillous trophoblasts: 79.9;Oligodendrocyte precursor cells: 44.7;Oligodendrocytes: 45.3;Theca cells: 43.7" "Cancer enriched" "Detected in some" 15 "testis cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;HAP1: 20.4;K-562: 12.0;NTERA-2: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019032, HPA057273" Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane" "HPA019032: AB_1847363, HPA057273: AB_2683391" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "unprognostic (9.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (8.15e-2)" "unprognostic (3.60e-3)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (7.90e-3)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-3)" "unprognostic (2.88e-4)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (9.52e-3)" 0.4 0.2 0.6 0.2 1.2 0.3 0.4 4.9 0.7 0.7 0.8 0.4 0.1 0.9 0.6 0.2 0.5 0.3 0.3 0.3 0.9 0.3 0.2 0.2 0.3 0.9 1.3 0.8 0.2 0.7 0.3 1.2 1.1 0.6 0.3 1.5 1.0 0.3 0.9 0.3 0.2 0.5 1.0 0.3 0.4 0.2 1.1 2.0 0.5 0.3 0.3 0.2 0.4 2.2 0.7 0.8 8.0 9.0 0.8 0.7 17.7 0.4 1.0 0.7 1.2 5.5 0.3 0.0 0.3 0.8 0.1 0.0 20.4 0.0 0.8 0.3 3.3 2.1 0.0 4.9 1.2 1.9 1.0 1.0 0.1 0.5 0.1 1.6 0.1 3.5 12.0 1.4 0.7 0.6 3.3 1.4 11.9 0.0 1.1 3.2 2.5 0.2 0.4 0.8 2.2 3.5 0.4 0.5 1.6 7.9 1.0 1.5 0.3 0.7 1.6 0.0 0.6 0.5 0.6 3.2 0.2 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.2 0.5 0.0 0.6 1.2 4.9 0.7 0.3 0.9 0.9 1.3 1.1 1.0 1.1 2.2 6.3 3.2 6.2 54.5 2.5 1.1 1.8 0.4 5.2 2.5 7.0 9.5 7.2 1.5 2.6 0.0 10.4 21.0 3.0 0.2 0.0 2.7 0.8 3.6 34.2 4.8 13.8 2.5 15.6 0.4 79.9 15.4 1.5 2.9 0.0 13.6 5.7 2.5 3.9 35.3 20.6 0.3 4.1 0.0 0.3 1.7 25.7 0.8 1.8 12.2 0.4 16.1 5.2 44.7 45.3 0.6 0.0 20.7 7.3 1.4 0.0 0.9 0.8 12.5 6.6 21.9 10.7 0.5 1.5 0.8 1.1 27.9 2.6 43.7 0.6 0.4 TET2 "FLJ20032, KIAA1546" ENSG00000168769 "Tet methylcytosine dioxygenase 2" Q6N021 4 105145875-105279816 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 55.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043135 Supported Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA043135: AB_10794177" "unprognostic (6.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.69e-2)" "unprognostic (9.42e-2)" "unprognostic (4.15e-2)" "unprognostic (5.88e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-3)" "unprognostic (1.15e-2)" "unprognostic (1.57e-2)" "unprognostic (5.77e-2)" "unprognostic (7.29e-2)" "unprognostic (2.70e-3)" "unprognostic (6.10e-2)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.84e-2)" 4.3 3.1 2.9 10.1 4.4 22.4 5.4 2.5 2.7 6.3 5.8 5.2 6.1 7.2 6.0 7.7 4.9 5.0 3.3 2.1 4.6 4.1 4.2 5.4 5.6 5.3 4.4 4.3 3.7 4.6 1.8 10.2 5.3 4.4 5.9 6.6 4.7 3.3 2.8 11.0 6.0 5.7 2.9 7.2 5.3 1.3 4.1 5.4 4.2 5.2 7.0 5.5 4.5 5.6 5.1 3.1 10.9 11.1 2.1 3.7 4.2 3.1 4.8 4.8 4.7 3.1 6.4 0.5 4.0 4.0 2.1 4.9 9.3 6.1 5.3 6.7 2.9 7.0 6.5 1.6 4.9 15.5 11.8 3.8 7.9 4.5 5.6 8.6 6.4 4.1 7.7 13.6 4.4 3.1 2.5 4.7 2.5 6.2 2.2 8.4 4.7 1.0 4.7 9.4 7.5 5.9 4.2 9.1 0.8 5.9 4.5 11.8 9.1 7.8 6.7 2.1 5.3 9.5 6.8 6.8 4.8 3.8 7.2 30.1 13.6 14.7 3.9 10.4 1.6 5.3 2.3 2.2 10.2 6.3 1.9 2.9 55.5 5.9 13.6 8.9 3.1 3.3 2.9 4.4 2.5 2.7 2.1 4.6 5.3 4.4 5.3 2.9 4.1 5.6 24.5 25.6 29.1 58.8 28.3 14.4 11.0 14.2 12.5 22.8 15.6 13.6 27.9 5.7 23.9 9.2 16.7 23.1 34.1 19.0 7.9 7.0 0.4 22.1 38.3 20.3 23.3 10.9 48.4 7.5 5.7 18.0 21.4 33.2 27.8 15.5 13.6 8.5 14.5 35.3 89.7 15.8 32.6 48.8 93.3 0.9 8.1 98.3 5.4 90.9 48.1 5.8 34.0 112.6 128.3 8.2 18.7 7.2 22.5 12.1 16.3 2.8 22.3 24.3 13.1 47.0 21.7 0.2 1.3 28.4 35.9 34.2 18.9 24.7 14.0 27.5 TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "liver: 7525.8;retina: 2433.0" "Group enriched" "Detected in many" 9 "Hepatocytes: 7205.2;Muller glia cells: 12965.3" "Cancer enriched" "Detected in many" 42 "liver cancer: 783.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 48 "Hep G2: 780.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" NA NA 19800000000000 98000000000 "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "CAB009538: AB_793365, HPA001527: AB_1080357, HPA005692: AB_1080354" "prognostic favorable (4.05e-4)" "unprognostic (2.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.50e-1)" "unprognostic (8.99e-2)" "unprognostic (5.18e-2)" "unprognostic (6.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (2.35e-13)" "unprognostic (2.17e-3)" "unprognostic (5.49e-2)" "unprognostic (3.47e-3)" "unprognostic (9.70e-2)" 80.9 1.2 186.3 1.0 412.5 2.4 13.3 591.8 274.2 2.0 58.9 2.3 0.9 1.7 1.4 11.0 1.4 1.9 12.1 173.7 287.7 3.4 7525.8 1.9 1.3 786.9 385.4 2.1 4.6 2.2 4.4 1.3 628.2 5.4 1.2 2433.0 55.8 1.8 2.1 4.2 1.6 1.5 484.9 2.9 1.9 14.3 398.1 1.2 2.2 2.7 3.0 1.2 2.8 862.1 1.9 1.4 1.8 1.2 5.5 3.4 0.9 1.9 2.0 1.0 0.8 3.4 1.5 1.7 1.6 1.8 1.2 2.1 1.3 1.8 1.5 1.1 0.7 16.3 2.7 780.9 1.3 4.6 2.7 2.4 3.8 1.0 1.7 1.8 2.2 0.9 6.4 2.1 2.6 1.3 1.1 1.2 1.2 1.2 1.8 1.5 2.9 1.2 1.1 3.1 1.9 1.4 2.4 2.6 7.0 1.3 1.9 1.3 2.9 2.4 1.5 1.6 1.1 1.7 3.0 1.4 2.0 1.5 1.6 0.6 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 186.3 412.5 591.8 274.2 173.7 287.7 786.9 385.4 628.2 484.9 398.1 862.1 0.7 16.0 32.4 36.2 11.4 1.0 5.6 0.6 0.0 101.3 5.3 4.3 2.7 117.2 22.9 0.0 91.8 0.2 0.2 0.1 1.9 0.7 5.4 0.8 1.0 16.7 0.0 56.2 34.2 1.1 0.3 3.9 0.0 0.6 17.7 1.3 87.4 7205.2 0.1 47.1 34.7 0.0 0.0 124.7 0.3 3.8 0.3 4.7 0.0 9.4 0.6 12965.3 0.0 45.2 1077.2 1.1 0.0 0.4 0.0 18.7 0.0 0.5 22.1 400.4 0.0 11.6 0.4 0.5 0.4 3.6 0.0 0.3 7.8 0.5 0.0 3.0 TFAP2B AP2-B ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 33.3;retina: 14.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 145.7;Bipolar cells: 76.4;Horizontal cells: 437.4;Melanocytes: 106.7" "Cancer enriched" "Detected in some" 8 "breast cancer: 12.1" "Group enriched" "Detected in many" 6 "cerebellum: 3.5;medulla oblongata: 3.9;midbrain: 9.0;pons: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 109.6;SH-SY5Y: 208.1" "Region enhanced" "Detected in many" "cerebellum: 10.0" "Low region specificity" "Detected in many" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA034683: AB_10670966, HPA062942: AB_2684909" "unprognostic (2.02e-1)" "unprognostic (2.29e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-4)" "unprognostic (9.76e-2)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.57e-1)" "unprognostic (6.58e-6)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (7.17e-3)" 0.1 3.4 0.0 0.0 0.0 0.0 8.2 3.5 0.1 0.1 0.0 0.1 0.0 0.0 33.3 3.9 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 3.9 9.0 0.0 0.0 0.0 0.6 0.2 10.2 0.0 0.0 14.8 6.4 0.7 0.0 8.6 0.0 0.0 0.6 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 109.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 35.5 0.1 0.2 208.1 0.0 0.8 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.1 3.9 9.0 10.2 0.6 1.1 0.2 0.2 0.0 0.0 0.0 0.0 11.7 0.0 0.0 145.7 76.4 43.0 29.7 0.9 0.0 0.0 51.5 8.4 14.9 0.1 0.0 54.8 0.0 17.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 437.4 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.5 106.7 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.7 0.0 11.8 0.0 0.0 0.3 1.9 0.6 31.1 4.3 4.9 0.2 0.0 0.0 0.0 TFDP1 "DILC, Dp-1, DP1, DRTF1" ENSG00000198176 "Transcription factor Dp-1" Q14186 13 113584721-113641473 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 164.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 344.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 31.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 31.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033605, HPA044754, HPA068909, HPA077304" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "Nuclear membrane, Cytosol" "CAB033605: AB_783105, HPA044754: AB_2679074, HPA068909: AB_2686056, HPA077304: " "unprognostic (4.28e-2)" "unprognostic (9.50e-3)" "unprognostic (1.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.01e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (5.50e-3)" "unprognostic (1.68e-2)" "unprognostic (3.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.43e-2)" "prognostic favorable (7.57e-4)" "prognostic favorable (6.17e-4)" "unprognostic (2.30e-1)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" 28.2 23.5 24.3 38.6 24.0 164.0 27.2 24.5 24.4 33.5 32.5 37.8 30.5 27.6 19.4 50.1 32.8 24.6 34.3 24.1 22.8 23.2 25.9 21.8 67.1 27.5 24.4 19.3 18.4 28.5 21.3 40.6 25.3 26.1 42.4 20.2 26.1 30.8 58.2 42.8 32.3 34.3 26.6 30.8 31.3 49.6 26.8 53.4 33.1 59.0 68.3 37.5 30.1 25.7 343.2 82.5 104.4 89.5 138.4 122.7 118.5 187.8 168.7 238.1 218.6 173.3 155.9 314.6 61.3 181.3 130.3 160.3 183.0 167.1 232.2 215.9 212.8 184.4 129.2 109.8 86.8 468.3 155.7 102.1 147.3 151.3 87.4 85.0 162.7 116.2 154.1 82.6 215.5 117.7 207.0 181.4 96.6 322.7 105.0 138.9 93.0 181.1 91.3 129.1 268.2 79.3 84.8 228.8 58.7 75.1 157.9 371.7 114.4 77.2 122.9 165.6 210.8 69.5 92.4 326.4 171.9 285.2 133.2 31.9 3.0 4.6 3.1 3.8 3.4 4.4 4.1 3.7 5.9 3.6 6.3 3.2 3.8 2.3 5.5 3.0 5.3 2.5 24.3 24.0 24.5 24.4 24.1 22.8 27.5 24.4 25.3 26.6 26.8 25.7 21.4 9.6 15.8 12.7 38.8 59.8 32.1 16.1 33.6 10.3 45.6 35.2 26.6 28.6 14.7 29.5 14.6 83.2 33.8 29.8 80.3 12.3 5.5 34.4 28.2 25.8 40.2 344.3 22.5 11.9 128.0 30.8 38.7 31.0 21.0 23.3 34.6 58.7 49.2 6.7 19.5 36.1 12.2 49.1 51.2 10.7 28.6 41.1 35.6 5.6 24.8 14.7 16.5 9.5 10.2 19.0 24.2 28.2 67.3 35.7 29.4 66.5 21.0 22.5 6.6 20.0 32.7 76.7 52.7 74.6 60.0 66.6 32.1 30.3 47.4 35.8 TFDP2 Dp-2 ENSG00000114126 "Transcription factor Dp-2" Q14188 3 141944428-142149544 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 169.7" "Cell type enhanced" "Detected in all" "Early spermatids: 986.1;Late spermatids: 397.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 216.4;MOLT-4: 423.3;REH: 222.7;U-698: 366.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018396, HPA070399" Supported Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes No "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Vesicles, Mitotic spindle" "CAB018396: AB_2287284, HPA070399: " "unprognostic (1.35e-2)" "prognostic favorable (6.32e-4)" "unprognostic (8.08e-3)" "unprognostic (2.90e-2)" "unprognostic (4.69e-2)" "unprognostic (1.18e-1)" "unprognostic (1.14e-3)" "unprognostic (2.60e-3)" "unprognostic (5.42e-2)" "unprognostic (1.46e-1)" "unprognostic (5.04e-2)" "unprognostic (2.04e-1)" "prognostic favorable (9.84e-4)" "unprognostic (6.04e-2)" "unprognostic (3.91e-2)" "unprognostic (2.45e-1)" "unprognostic (1.08e-1)" 18.8 15.1 7.8 9.2 8.9 50.3 18.9 21.2 12.7 12.1 8.2 14.8 22.7 15.3 15.9 13.7 14.7 19.4 26.0 9.0 7.0 29.5 17.3 11.8 10.5 12.5 10.6 23.3 12.4 16.7 13.0 28.4 12.4 19.4 14.0 13.2 12.3 13.7 28.5 11.9 21.3 14.4 7.4 9.5 12.4 69.9 8.2 169.7 21.6 21.3 10.6 11.2 10.2 10.0 32.8 14.7 61.6 49.4 20.3 21.9 134.0 16.3 18.8 25.5 40.2 19.2 32.2 115.8 73.7 18.7 44.6 19.5 15.8 31.2 35.8 46.9 28.5 140.4 21.5 26.0 19.6 43.1 47.8 20.6 22.8 27.8 26.9 23.5 18.3 216.4 53.5 6.8 44.3 25.4 423.3 16.1 49.6 17.2 20.0 222.7 42.2 27.0 29.4 16.5 26.9 25.0 54.5 19.5 29.0 45.3 46.7 21.9 12.0 24.2 21.9 19.8 20.7 20.7 20.5 366.5 19.4 11.4 11.6 69.3 4.0 48.0 28.0 6.9 10.9 14.7 12.8 14.9 9.8 18.7 18.6 22.2 4.4 37.4 10.0 33.7 12.8 12.5 7.8 8.9 21.2 12.7 9.0 7.0 12.5 10.6 12.4 7.4 8.2 10.0 29.7 32.1 30.6 64.0 24.2 25.1 52.1 30.4 43.3 33.0 45.1 36.8 87.6 45.8 30.7 47.8 33.3 235.4 98.5 23.1 93.9 36.8 986.1 63.9 51.1 26.8 38.6 171.9 194.6 26.4 125.2 44.0 15.8 35.8 33.5 84.8 27.8 39.8 27.8 37.0 166.7 27.1 40.7 13.5 15.4 397.5 77.0 27.0 5.4 51.5 14.9 26.1 128.8 61.9 116.6 27.2 25.7 75.2 25.2 36.3 87.5 98.4 43.1 34.5 26.3 96.7 38.6 75.4 75.6 31.3 20.0 99.2 42.9 72.4 42.0 36.0 TFE3 "bHLHe33, TFEA" ENSG00000068323 "Transcription factor binding to IGHM enhancer 3" P19532 X 49028726-49043410 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.5" "Group enriched" "Detected in many" 4 "granulocytes: 12.5;monocytes: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023881 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA023881: AB_1857931" "unprognostic (2.68e-2)" "unprognostic (2.89e-3)" "unprognostic (2.40e-2)" "unprognostic (5.36e-2)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (6.03e-5)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "unprognostic (4.32e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.19e-8)" "unprognostic (1.93e-1)" "unprognostic (8.77e-2)" "unprognostic (4.19e-2)" "unprognostic (6.25e-1)" 31.3 23.6 27.8 16.8 27.3 24.1 22.9 25.8 26.9 24.1 23.3 23.6 10.8 24.7 21.1 15.6 26.2 18.5 17.2 25.7 29.4 15.1 12.6 29.2 11.8 37.2 30.9 25.8 12.4 25.1 18.4 20.8 28.7 17.2 11.5 14.8 13.4 28.3 17.0 20.5 14.7 24.7 27.5 22.5 16.8 5.9 32.2 10.7 20.0 14.0 13.2 25.0 20.5 25.6 32.8 41.5 14.6 44.6 48.6 45.1 12.5 40.6 55.8 49.7 38.2 23.3 26.8 10.2 18.0 65.7 48.6 25.5 25.4 40.2 44.8 24.4 11.8 8.3 39.6 26.2 69.0 10.0 28.3 38.5 32.3 64.4 50.1 47.8 26.3 8.4 19.8 55.9 49.2 20.6 7.5 17.2 36.3 11.0 34.1 11.9 22.2 26.6 43.1 18.0 12.4 12.4 44.8 19.0 17.9 52.5 27.6 15.0 48.5 47.1 48.7 48.0 27.3 30.1 29.7 8.0 56.1 14.0 33.2 0.0 4.8 1.8 0.6 4.7 1.1 0.5 0.9 0.5 2.2 1.0 0.6 0.5 12.5 0.4 6.3 0.5 1.3 2.6 27.8 27.3 25.8 26.9 25.7 29.4 37.2 30.9 28.7 27.5 32.2 25.6 13.8 16.0 8.8 13.7 9.8 19.8 19.7 11.2 30.1 6.8 10.9 9.4 8.1 15.7 11.8 20.2 4.2 16.0 4.4 14.3 9.8 17.7 0.7 10.9 15.3 17.5 12.5 5.2 7.5 15.8 9.4 20.2 14.3 14.8 5.7 12.0 10.8 15.0 22.3 18.5 7.2 8.2 0.0 21.7 29.4 2.2 27.4 20.5 8.8 11.2 15.5 12.0 4.1 6.0 7.7 21.4 13.7 24.5 12.9 20.2 10.6 12.1 7.0 5.6 13.1 18.5 14.3 2.2 0.8 18.9 22.0 37.1 8.6 13.9 7.5 19.6 TFEB "bHLHe35, TCFEB" ENSG00000112561 "Transcription factor EB" P19484 6 41683978-41736259 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Autophagy, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 89.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 97.4;Syncytiotrophoblasts: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 16.1;eosinophil: 16.9;intermediate monocyte: 16.3;memory B-cell: 34.2;myeloid DC: 14.7;naive B-cell: 22.6;neutrophil: 47.4;non-classical monocyte: 14.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 60.3;Daudi: 35.8;OE19: 53.1;U-698: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067082 Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Cytosol "HPA067082: " "unprognostic (3.63e-3)" "unprognostic (1.51e-3)" "unprognostic (1.75e-2)" "unprognostic (4.48e-3)" "unprognostic (1.95e-1)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (4.22e-3)" "unprognostic (1.39e-2)" "unprognostic (4.13e-2)" "prognostic favorable (4.77e-4)" "unprognostic (2.12e-2)" "prognostic favorable (1.06e-5)" "unprognostic (1.44e-1)" "unprognostic (3.51e-2)" "unprognostic (2.46e-1)" "unprognostic (1.31e-2)" 14.3 10.7 18.3 16.7 29.9 8.3 15.0 24.0 23.5 13.4 9.6 25.7 5.8 11.1 1.5 14.8 12.8 7.7 37.1 18.1 19.7 26.7 11.6 18.2 26.1 30.9 27.7 6.5 12.9 17.8 31.3 14.5 25.8 23.4 4.3 2.2 21.2 7.0 89.9 17.9 34.6 5.7 22.5 57.2 14.4 2.6 25.4 5.0 22.9 41.5 17.2 19.6 15.6 39.9 3.5 3.2 0.6 12.3 3.8 2.5 60.3 5.3 6.9 3.4 2.7 6.9 2.7 35.8 6.8 3.5 2.9 8.7 2.4 4.9 1.0 28.3 4.1 0.1 8.8 12.8 6.8 1.0 4.3 0.7 9.8 4.9 2.6 6.9 4.1 3.3 4.1 7.4 1.0 1.8 2.3 1.2 0.1 53.1 1.6 24.3 0.1 5.0 7.5 2.6 12.8 4.3 4.7 10.5 1.0 3.4 2.3 19.5 7.1 1.5 3.1 0.1 3.0 15.7 2.3 42.1 2.6 15.3 0.9 0.3 16.1 16.9 3.8 16.3 0.9 34.2 1.5 1.8 14.7 22.6 0.4 1.5 47.4 1.7 14.1 2.9 0.6 8.7 18.3 29.9 24.0 23.5 18.1 19.7 30.9 27.7 25.8 22.5 25.4 39.9 14.5 9.6 9.3 10.1 36.7 14.1 8.2 14.8 5.2 6.1 5.7 5.6 19.2 10.0 6.0 12.9 12.5 50.7 13.8 16.3 21.5 3.7 1.1 11.4 2.6 12.2 13.2 3.2 6.3 6.9 8.3 6.9 6.1 8.0 1.3 0.5 6.4 4.2 26.8 26.9 7.9 10.2 26.4 22.8 13.3 4.2 3.4 19.6 0.0 17.8 20.0 18.4 22.6 11.1 97.4 10.6 18.0 10.9 16.0 7.1 14.1 3.7 7.4 5.2 6.6 13.1 7.8 0.9 1.0 6.4 14.5 120.4 9.1 0.8 8.8 6.3 TFF1 "BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2" ENSG00000160182 "Trefoil factor 1" P04155 21 42362282-42366535 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "stomach 1: 7973.0" "Group enriched" "Detected in many" 9 "Gastric mucus-secreting cells: 12908.9;Pancreatic endocrine cells: 14603.3" "Group enriched" "Detected in many" 10 "breast cancer: 402.1;colorectal cancer: 268.3;pancreatic cancer: 805.7;stomach cancer: 744.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "MCF7: 13512.4;OE19: 5337.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002170, HPA003425" Enhanced "Secreted to digestive system" NA NA 950000 "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB002170: AB_563985, HPA003425: AB_1848260" "prognostic favorable (5.00e-4)" "unprognostic (8.81e-3)" "unprognostic (9.82e-2)" "prognostic favorable (5.67e-4)" "unprognostic (2.42e-1)" "unprognostic (1.72e-3)" "unprognostic (8.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" "unprognostic (6.62e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (7.72e-3)" "unprognostic (1.07e-1)" 2.3 0.3 0.0 20.3 0.0 0.0 26.7 0.0 0.0 9.7 0.0 114.7 34.8 0.2 0.0 18.3 0.9 167.2 0.6 0.0 0.0 0.9 0.8 1.3 0.2 0.0 0.0 0.2 10.7 0.0 0.2 1.1 0.0 25.0 108.4 0.0 32.4 0.7 0.2 0.1 68.4 4.8 0.0 3.1 7973.0 0.1 0.0 0.2 5.3 0.0 0.2 30.6 2.2 0.0 0.0 42.7 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 16.2 5.7 0.0 1.1 0.0 1.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 13512.4 4.6 0.5 5.5 5337.9 223.4 1.7 0.0 0.2 0.0 1.4 0.3 0.2 0.0 5.0 0.0 1.3 5.0 0.1 0.0 0.0 3.5 0.1 0.0 3.6 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 18.7 0.0 6.1 5.9 0.0 0.0 432.7 197.2 0.0 564.7 12.1 35.0 0.0 0.1 3.1 601.9 0.0 245.7 0.0 1.8 0.2 3.5 430.2 0.0 0.0 821.8 3.1 5.1 12908.9 2.9 13.4 0.0 0.0 1.6 0.2 0.0 0.0 1395.6 111.9 0.0 0.0 0.0 0.0 9.2 0.0 0.0 10.3 0.0 0.0 0.0 0.0 14603.3 500.9 0.0 40.6 432.4 78.0 0.0 2.8 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 8.9 0.0 80.0 232.6 TFF2 SML1 ENSG00000160181 "Trefoil factor 2" Q03403 21 42346357-42350997 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 6852.1" "Group enriched" "Detected in some" 5 "Cholangiocytes: 2057.4;Gastric mucus-secreting cells: 7217.7" "Group enriched" "Detected in many" 11 "pancreatic cancer: 320.9;stomach cancer: 244.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.4;Karpas-707: 20.0;OE19: 55.4;PC-3: 145.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025834, HPA036705" Enhanced "Secreted to digestive system" NA NA 890000 "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB025834: , HPA036705: AB_2675263" "unprognostic (3.95e-2)" "unprognostic (9.87e-2)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.89e-2)" "unprognostic (5.55e-2)" "unprognostic (1.27e-9)" "unprognostic (1.99e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (5.26e-3)" 1.4 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.8 0.0 6.5 1424.4 0.1 0.0 3.4 1.2 105.4 0.2 0.0 0.0 0.3 4.0 1.0 0.0 0.0 0.0 0.0 17.2 0.0 0.2 1.0 0.0 0.1 4.2 0.0 2.9 0.0 0.1 0.1 0.5 0.2 0.0 2.7 6852.1 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 35.4 0.0 0.2 0.0 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 2.9 0.0 2.6 55.4 145.2 1.1 0.0 8.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.1 0.0 0.0 2.7 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.0 0.0 0.0 0.0 3.6 0.5 0.2 2057.4 0.0 0.0 0.0 0.0 0.0 3.4 0.0 104.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 93.8 0.2 1.3 7217.7 0.0 0.0 0.5 0.0 6.1 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 2.9 5.4 0.0 0.6 0.0 0.0 0.0 0.0 833.8 5.5 0.0 11.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.0 0.0 0.1 11.8 TFF3 "HITF, ITF" ENSG00000160180 "Trefoil factor 3" Q07654 21 42311667-42315651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 305.8;intestine: 355.3;salivary gland: 340.2;thyroid gland: 416.7" "Cell type enriched" "Detected in many" 10 "Intestinal goblet cells: 33890.3" "Cancer enhanced" "Detected in all" "colorectal cancer: 765.0" "Region enriched" "Detected in single" 6 "midbrain: 1.9" "Immune cell enriched" "Detected in single" 9 "eosinophil: 1.8" "Lineage enriched" "Detected in single" 18 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "MCF7: 58.7;OE19: 126.6;T-47d: 27.8;TIME: 105.0" "CAB020681, HPA035464" Enhanced Approved Nucleoplasm,Nucleoli "Secreted to blood" No NA 151000000 6500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Nucleoli "CAB020681: , HPA035464: AB_2674636" "unprognostic (2.84e-2)" "unprognostic (3.61e-3)" "unprognostic (1.07e-1)" "prognostic favorable (5.60e-6)" "unprognostic (1.28e-1)" "unprognostic (2.35e-2)" "unprognostic (2.13e-1)" "unprognostic (5.03e-2)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (3.71e-1)" "unprognostic (6.90e-2)" "unprognostic (4.31e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" "unprognostic (3.86e-2)" 11.5 5.9 0.1 27.8 0.1 2.2 26.3 0.3 0.2 305.8 0.1 355.3 208.0 2.8 0.5 22.7 49.8 82.8 3.5 0.1 0.1 5.7 6.6 9.9 3.5 0.1 1.9 3.5 6.1 0.0 1.3 0.1 0.2 9.8 305.8 0.1 340.2 1.6 0.9 6.7 290.6 8.4 0.1 23.1 7.4 0.5 0.2 1.8 416.7 1.7 0.9 3.6 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 58.7 0.0 0.7 0.1 126.6 12.1 0.0 9.0 0.3 0.1 0.0 16.1 0.1 0.0 1.7 0.0 0.0 27.8 0.0 105.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 1.9 0.2 0.1 0.2 0.1 36.9 16.0 25.3 0.0 15.4 41.6 15.1 196.3 3.4 0.1 804.5 444.7 21.6 919.3 595.9 22.0 0.0 0.6 3.4 2188.7 0.0 9.4 0.5 29.3 1.4 322.8 770.9 0.0 0.0 67.8 0.7 21.5 71.4 11.4 59.2 2.0 170.3 5.8 2.1 5.0 0.0 33890.3 3263.2 3.4 42.4 9.0 2.5 2.8 96.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 1855.5 7.9 6.1 73.0 2788.7 0.1 453.2 0.1 0.0 1.1 28.2 1.0 0.3 4.3 38.6 0.8 14.9 0.6 1376.3 107.7 TFG "FLJ36137, SPG57, TF6" ENSG00000114354 "Trafficking from ER to golgi regulator" Q92734 3 100709295-100748964 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019473, HPA052206" Approved Supported Vesicles,Cytosol No No 320000 "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles Cytosol "HPA019473: AB_1857936, HPA052206: AB_2681760" "unprognostic (1.14e-1)" "unprognostic (3.58e-2)" "unprognostic (1.46e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (3.31e-3)" "unprognostic (1.42e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (4.58e-3)" "unprognostic (3.72e-2)" "unprognostic (2.82e-1)" "unprognostic (8.55e-2)" "unprognostic (3.33e-1)" "unprognostic (8.45e-2)" 62.2 73.0 40.7 37.2 40.4 37.4 52.4 43.5 46.4 53.9 46.7 63.8 89.8 52.0 78.5 85.7 51.2 56.4 82.6 41.3 45.4 71.9 113.9 55.6 29.4 44.2 43.2 48.2 66.7 89.0 64.1 79.2 44.4 47.9 69.6 40.9 60.6 61.3 75.5 58.9 76.6 66.5 43.2 42.6 54.4 47.7 42.3 40.6 64.1 58.2 54.9 61.6 57.3 44.4 203.8 107.5 126.7 79.0 160.1 176.4 163.9 141.1 190.4 182.5 213.0 136.0 96.1 24.7 103.3 180.4 141.3 143.1 143.4 161.5 216.2 123.8 87.4 99.7 69.3 130.0 183.3 70.2 51.8 149.3 216.6 108.4 190.8 165.1 165.5 44.5 73.1 63.5 191.9 143.9 63.3 56.7 122.5 193.8 169.3 55.5 77.8 89.0 226.5 125.9 96.4 93.1 95.0 118.2 175.8 103.4 141.7 103.1 113.1 103.0 130.8 48.4 104.4 56.2 65.8 92.1 171.2 79.7 130.7 84.3 43.6 42.8 30.8 45.2 37.4 37.4 31.6 34.5 43.1 35.9 29.4 29.7 26.1 43.1 44.8 29.3 41.0 37.0 40.7 40.4 43.5 46.4 41.3 45.4 44.2 43.2 44.4 43.2 42.3 44.4 67.9 60.9 36.9 46.4 43.3 136.6 105.9 183.6 69.4 46.8 58.0 50.2 83.5 48.6 93.1 36.8 25.0 211.6 43.1 111.8 137.0 190.3 101.5 70.8 70.4 70.2 52.6 27.1 54.8 107.7 201.5 97.8 47.4 79.0 76.8 62.9 53.9 68.4 86.2 57.2 59.2 128.5 122.1 27.3 84.9 45.5 70.8 43.6 64.0 38.4 98.5 88.0 28.8 49.3 55.0 130.5 91.0 74.1 75.8 133.5 202.5 106.4 63.9 60.3 39.5 81.3 87.2 79.2 51.5 68.0 118.9 284.4 43.2 90.0 97.2 123.0 TFRC "CD71, p90, TFR1" ENSG00000072274 "Transferrin receptor" P02786 3 196027183-196082096 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 254.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 556.4;Syncytiotrophoblasts: 502.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 860.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000153, HPA028598" Enhanced Supported Endosomes,Lysosomes "Secreted to blood" NA NA 1310000000 38000000 "Cluster 27: Non-specific - Gene expression" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Endosomes, Lysosomes" "CAB000153: AB_2533029, HPA028598: AB_10601599" "unprognostic (2.95e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" "unprognostic (6.75e-2)" "unprognostic (7.88e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.92e-2)" "unprognostic (3.30e-3)" "unprognostic (4.35e-2)" "unprognostic (1.34e-2)" "unprognostic (1.14e-2)" "unprognostic (3.63e-3)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (2.96e-4)" "unprognostic (2.62e-2)" 44.6 28.7 21.6 63.4 18.3 254.5 20.2 18.5 32.3 31.3 15.7 77.2 35.9 23.8 11.1 36.0 25.9 24.9 31.0 21.9 19.0 26.4 27.8 78.0 23.0 24.2 19.9 93.9 15.9 44.8 13.1 103.2 26.3 13.2 55.6 47.3 15.7 13.4 76.2 21.8 32.1 31.5 20.8 15.5 21.4 21.6 25.3 22.0 20.1 68.7 28.1 68.5 17.4 20.7 175.3 155.0 69.8 142.1 151.7 87.3 438.7 242.5 183.7 168.1 276.3 384.6 156.6 178.5 446.3 91.0 363.5 261.8 243.3 81.1 204.2 860.4 82.4 677.4 120.2 179.2 119.4 561.8 130.4 99.1 78.6 144.5 129.0 47.8 56.9 95.6 287.3 164.1 132.8 161.7 185.8 116.8 214.9 228.6 314.0 97.3 103.9 214.1 148.3 435.3 159.3 65.9 234.4 613.9 55.2 115.9 595.0 115.8 72.5 198.4 159.7 175.3 369.7 46.3 387.8 276.7 232.3 149.2 122.3 0.0 1.6 2.2 2.2 7.3 1.4 5.1 2.4 1.5 3.5 3.1 2.1 1.7 0.2 1.9 13.2 7.1 6.4 2.1 21.6 18.3 18.5 32.3 21.9 19.0 24.2 19.9 26.3 20.8 25.3 20.7 25.4 44.8 32.1 43.1 46.6 60.3 37.2 33.6 21.1 53.1 37.1 34.9 103.0 41.5 38.8 20.2 148.0 122.5 53.2 156.6 0.0 49.4 3.5 35.3 20.3 23.6 56.1 556.4 24.7 41.8 25.3 32.4 77.5 56.1 23.4 40.2 8.6 93.2 73.4 13.5 28.3 67.8 22.4 37.1 77.6 5.3 11.5 161.7 17.8 44.0 49.4 22.0 9.2 11.6 8.2 52.0 50.8 8.6 42.1 25.6 48.3 13.1 32.1 44.4 26.3 36.3 29.3 23.8 18.2 51.3 35.8 502.7 42.6 16.6 103.5 23.7 TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 9329.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 5.5;Cardiomyocytes: 3.0;Early spermatids: 2.3;Late spermatids: 2.2;Microglial cells: 1.9;Proximal tubular cells: 4.0" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;HSkMC: 2.4;Karpas-707: 5.6;PC-3: 2.8;U-266/70: 2.0;U-266/84: 1.8" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in some" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" 1.6 3.2 3.0 0.5 0.4 7.8 1.4 0.2 1.9 1.2 1.5 1.8 0.0 1.8 1.0 2.0 0.4 8.6 13.6 1.7 0.2 2.9 3.6 4.2 12.0 0.4 0.5 1.2 8.0 2.7 1.2 0.2 0.5 3.6 0.1 0.1 3.9 1.8 2.8 6.3 1.7 0.1 0.2 1.9 2.2 2.9 0.5 0.4 9329.0 0.0 0.6 0.6 1.7 0.5 0.0 0.0 0.0 0.0 0.5 0.7 0.3 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.4 1.7 0.6 0.0 0.5 0.0 0.7 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 2.0 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.1 0.1 3.0 0.4 0.2 1.9 1.7 0.2 0.4 0.5 0.5 0.2 0.5 0.5 0.3 0.0 0.6 0.3 0.2 0.0 5.5 0.1 0.0 0.0 0.1 0.1 3.0 0.0 1.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.3 0.3 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.4 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.5 0.1 0.1 0.0 0.4 0.1 0.5 0.0 4.0 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.0 0.6 0.0 0.2 1.1 0.0 1.2 TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 59.3;Pancreatic endocrine cells: 74.5;Urothelial cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.3;eosinophil: 23.8;neutrophil: 23.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 23.8" "Cell line enhanced" "Detected in many" "A-431: 72.5;CAPAN-2: 82.5;HBEC3-KT: 72.3;OE19: 54.6;RPTEC TERT1: 72.6;U-87 MG: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" No No 57900 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" 2.2 0.5 9.2 5.0 16.8 1.6 6.9 15.0 12.2 6.1 5.2 10.7 8.5 1.3 2.9 25.5 6.1 14.1 0.7 10.4 11.7 13.4 4.5 3.9 4.1 21.0 15.8 0.1 7.5 3.0 0.5 1.9 18.5 2.4 7.9 7.4 6.4 1.2 0.1 12.2 10.0 1.4 16.6 5.8 8.5 2.5 13.2 1.0 8.1 0.3 9.0 10.0 12.8 27.3 72.5 11.3 0.1 0.2 0.0 0.0 0.0 11.0 0.0 0.3 0.1 0.2 82.5 0.0 43.2 0.4 11.2 37.1 0.6 72.3 0.1 0.1 1.6 0.0 1.8 6.0 0.0 0.9 0.1 0.0 29.1 0.1 27.8 3.4 0.0 5.6 0.0 0.4 0.0 2.6 0.1 1.4 1.1 54.6 22.9 0.0 0.5 19.8 72.6 27.2 0.6 0.1 5.8 0.0 0.1 0.2 9.8 0.7 0.6 0.3 4.9 0.1 15.7 0.4 0.6 0.1 69.0 2.4 25.6 11.3 0.8 23.8 1.7 0.2 4.4 0.0 1.0 1.0 1.0 0.0 0.5 0.4 23.8 0.3 0.0 0.0 0.0 0.7 9.2 16.8 15.0 12.2 10.4 11.7 21.0 15.8 18.5 16.6 13.2 27.3 0.4 6.4 2.7 0.3 0.2 16.2 12.3 16.9 10.8 1.4 9.8 12.1 2.3 24.3 21.8 25.8 0.0 0.0 2.2 19.8 1.9 37.3 21.3 8.1 0.7 1.7 1.2 0.0 0.8 10.0 0.0 0.6 13.7 10.5 5.7 0.0 0.0 3.0 3.9 0.0 3.6 6.2 12.2 3.2 2.4 1.9 0.3 4.1 0.0 6.5 18.2 7.9 2.1 59.3 36.1 74.5 9.0 0.0 0.7 16.8 21.1 6.6 20.4 0.7 0.0 0.1 1.1 0.6 0.2 12.2 24.9 0.0 1.9 0.0 5.6 63.6 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.9;Hepatic stellate cells: 322.7;Leydig cells: 146.3;Skeletal myocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 35.2" "Group enriched" "Detected in many" 18 "NK-cells: 16.6;T-cells: 35.2" "Cell line enhanced" "Detected in many" "ASC diff: 227.2;ASC TERT1: 108.4;RT4: 57.1;U-2197: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" NA NA 50000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB018971: , HPA008257: AB_1080258" "unprognostic (7.57e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (9.39e-3)" "prognostic favorable (4.84e-4)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "prognostic favorable (4.99e-4)" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.08e-2)" 66.3 35.2 6.9 9.2 6.8 5.0 62.1 7.6 8.0 56.6 20.4 28.8 8.2 33.9 24.2 28.5 36.6 20.0 16.2 7.6 6.7 28.2 16.6 27.3 7.2 6.0 10.1 81.5 12.3 5.9 7.1 58.5 7.8 16.4 12.5 1.5 35.0 32.7 12.8 25.0 19.7 27.4 7.9 40.0 18.1 11.0 8.0 7.7 13.2 29.4 4.2 47.3 28.6 7.8 9.9 9.4 14.1 2.4 227.2 108.4 44.6 7.1 35.3 8.1 9.9 4.4 1.4 0.1 1.7 13.0 6.4 1.4 3.6 1.0 6.2 34.1 7.6 0.0 11.1 41.2 5.0 0.3 0.1 26.3 4.7 17.8 4.0 1.3 4.2 0.0 23.6 0.7 2.4 0.2 0.1 0.1 5.9 4.6 3.2 0.5 4.8 2.1 3.2 57.1 0.7 0.0 3.4 0.2 20.4 5.8 1.2 3.7 12.7 13.5 3.5 78.0 1.7 34.8 3.3 0.0 2.8 1.9 1.7 1.2 0.0 0.0 35.2 0.2 19.4 0.0 8.7 19.2 0.0 0.0 2.7 12.7 0.6 16.6 1.4 1.2 4.5 8.1 6.9 6.8 7.6 8.0 7.6 6.7 6.0 10.1 7.8 7.9 8.0 7.8 77.6 9.6 9.7 58.8 3.1 37.6 10.0 2.3 44.3 0.3 38.2 60.1 20.7 30.0 4.2 31.3 2.1 27.5 66.7 0.5 3.9 2.0 54.3 11.2 32.8 90.5 24.0 10.7 7.7 5.1 12.0 143.9 5.1 8.1 2.5 20.5 322.7 21.0 11.8 0.0 34.0 1.9 8.2 23.2 29.4 29.8 146.3 5.2 35.6 82.4 0.7 1.2 62.8 7.5 0.9 3.3 0.4 74.4 21.3 8.5 1.4 20.9 8.3 0.2 13.1 187.2 36.5 0.8 2.2 17.2 34.1 58.0 36.9 92.2 3.7 8.0 TGIF1 "HPE4, TGIF" ENSG00000177426 "TGFB induced factor homeobox 1" Q15583 18 3411608-3459978 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 783.4;Basal respiratory cells: 419.8;Basal squamous epithelial cells: 483.2;Urothelial cells: 426.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062160 Supported Nucleoplasm NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA062160: AB_2684701" "unprognostic (1.11e-2)" "unprognostic (5.20e-2)" "unprognostic (2.40e-1)" "unprognostic (1.97e-1)" "unprognostic (3.57e-3)" "unprognostic (3.10e-2)" "unprognostic (2.75e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (9.60e-2)" "unprognostic (1.12e-2)" "unprognostic (9.81e-2)" "unprognostic (4.60e-1)" "unprognostic (7.07e-2)" "unprognostic (2.48e-3)" 51.2 40.1 21.7 43.3 20.8 41.5 57.6 22.4 25.7 68.9 30.2 51.5 31.6 51.2 133.7 46.7 74.7 65.3 29.8 20.2 29.3 74.0 61.5 47.6 26.4 29.8 27.3 67.3 46.9 26.9 22.0 63.8 25.7 54.6 65.7 8.0 56.5 56.1 34.4 60.2 37.8 37.4 27.5 35.5 49.1 25.9 25.7 40.0 66.7 26.9 27.0 112.1 40.0 28.4 33.6 148.5 92.7 29.3 90.0 121.7 235.7 63.1 236.6 49.9 62.1 61.0 142.6 1.9 20.9 49.8 165.7 33.7 35.0 73.8 61.6 13.9 16.8 4.3 73.2 110.5 178.8 47.6 38.3 89.5 291.7 89.7 233.7 131.3 104.4 22.3 36.0 0.4 95.6 65.8 31.1 58.8 240.8 119.0 34.8 32.8 43.2 10.3 198.1 156.7 27.1 26.5 166.2 123.0 92.5 151.3 28.1 43.7 49.6 77.5 65.6 92.7 41.1 5.0 0.6 15.7 78.5 18.6 98.2 65.4 42.8 7.6 62.9 16.6 67.8 46.5 52.5 61.9 35.1 32.2 37.1 43.5 19.8 21.5 16.7 3.3 32.1 36.3 21.7 20.8 22.4 25.7 20.2 29.3 29.8 27.3 25.7 27.5 25.7 28.4 41.0 35.3 40.2 8.1 106.5 359.6 783.4 419.8 483.2 0.0 114.1 72.1 5.6 100.1 128.3 123.2 0.0 161.6 60.1 30.0 49.0 117.1 41.5 167.2 58.5 66.6 46.4 25.7 2.7 75.0 220.9 102.8 79.0 240.2 68.0 71.5 29.3 35.7 71.8 1.7 0.6 99.4 136.3 44.9 221.1 9.7 28.6 126.8 76.5 7.5 71.9 6.7 11.3 4.0 1.7 106.0 53.0 15.4 15.1 308.1 24.9 113.1 93.3 0.1 32.9 90.9 86.6 7.9 15.4 223.9 257.1 150.4 103.7 8.0 91.8 426.2 TGM4 TGP ENSG00000163810 "Transglutaminase 4" P49221 3 44874608-44914990 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 377 "prostate: 434.4" "Cell type enriched" "Detected in some" 20 "Prostatic glandular cells: 226.6" "Cancer enriched" "Detected in single" 312 "prostate cancer: 75.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.9;hTERT-HME1: 1.3;NB-4: 2.7;RPMI-8226: 2.0;SH-SY5Y: 1.4" "Not detected" "Not detected" "CAB033571, HPA073290" Enhanced NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "CAB033571: AB_2287329, HPA073290: " "unprognostic (4.40e-2)" "unprognostic (4.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.17e-3)" "unprognostic (2.84e-1)" "unprognostic (2.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (2.41e-2)" "unprognostic (1.65e-1)" "unprognostic (8.56e-3)" "unprognostic (5.08e-2)" "unprognostic (1.44e-8)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (3.68e-1)" "unprognostic (6.41e-2)" 0.0 1.1 0.0 0.2 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 434.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.3 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.5 4.2 0.7 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.0 0.5 0.2 0.1 0.0 0.0 5.7 0.8 0.6 0.4 0.0 0.0 0.2 0.0 0.3 1.3 0.0 1.5 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.0 11.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.4 0.0 226.6 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.1 0.3 0.0 0.4 1.0 0.2 0.1 0.2 2.4 TGM7 TGMZ ENSG00000159495 "Transglutaminase 7" Q96PF1 15 43276271-43302255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.6" "Group enriched" "Detected in some" 11 "Early spermatids: 62.0;Late spermatids: 16.7" "Cancer enriched" "Detected in single" 13 "endometrial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 35 "EFO-21: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.5 THBS1 "THBS, THBS-1, TSP, TSP-1, TSP1" ENSG00000137801 "Thrombospondin 1" P07996 15 39581079-39599466 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, Unfolded protein response" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 279.5;Granulosa cells: 228.3;Macrophages: 598.0;Smooth muscle cells: 283.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 15.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2610.2;HUVEC TERT2: 2494.4;LHCN-M2: 1863.4;TIME: 3552.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.6" "CAB033678, HPA059756" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 16000000000 1400000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB033678: AB_793044, HPA059756: AB_2684121" "unprognostic (1.72e-2)" "unprognostic (9.55e-3)" "unprognostic (7.49e-2)" "unprognostic (3.31e-1)" "unprognostic (4.34e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (6.40e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (8.47e-5)" "prognostic unfavorable (8.50e-4)" "unprognostic (1.00e-1)" "unprognostic (9.25e-3)" "unprognostic (1.48e-3)" 364.3 72.5 1.7 394.0 3.7 114.7 95.1 2.1 11.3 66.7 27.3 166.4 24.8 161.3 3.5 49.1 142.6 275.2 98.3 2.2 2.1 70.9 129.4 309.2 32.3 10.8 4.4 76.3 69.1 7.0 26.8 99.0 10.8 89.8 85.6 0.4 137.3 12.0 16.2 35.4 83.5 243.6 0.9 79.8 150.5 2.2 14.3 12.0 34.0 4.3 7.1 396.3 36.2 2.1 171.9 62.7 49.0 17.8 199.4 233.9 0.7 1025.7 861.6 283.6 185.5 185.0 135.7 1.0 348.4 2610.2 54.4 621.0 2.2 516.1 145.0 43.4 0.5 46.6 35.0 46.9 44.4 0.3 13.2 524.9 37.2 237.2 535.1 1123.6 2494.4 1.6 1.5 1.7 1863.4 14.7 0.8 3.6 8.9 17.7 20.3 0.7 125.7 1.3 430.6 472.6 0.6 0.4 300.7 16.4 18.5 60.8 178.6 3.3 3552.9 972.6 221.0 1141.1 1146.6 2.4 1.8 2.0 33.0 0.8 1064.4 0.3 8.7 15.7 0.7 0.8 2.7 0.0 0.4 0.5 0.5 0.1 0.1 0.1 1.5 7.8 0.1 0.4 0.0 10.5 1.7 3.7 2.1 11.3 2.2 2.1 10.8 4.4 10.8 0.9 14.3 2.1 19.0 25.6 19.6 0.7 4.9 95.7 131.2 37.6 181.6 0.1 66.8 69.8 48.7 18.6 19.9 69.9 6.2 1.9 8.2 144.5 0.0 52.1 0.2 64.9 127.7 79.2 3.6 0.0 0.9 127.5 2.5 279.5 15.8 38.2 162.7 228.3 44.6 7.4 6.3 0.0 1.3 46.4 48.8 105.9 97.9 0.3 1.8 598.0 39.2 13.1 5.9 0.1 3.1 0.0 0.1 183.9 55.1 0.4 5.9 79.2 8.5 48.3 11.9 1.5 6.6 59.0 283.8 0.2 0.3 51.8 51.0 2.1 19.5 10.8 67.8 42.1 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 216.7;heart muscle: 167.9;smooth muscle: 251.4;tongue: 214.6" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 493.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.5" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.5" "Cell line enhanced" "Detected in some" "AF22: 3.1;THP-1: 7.0;U-2 OS: 2.8;U-266/70: 2.6" "Region enriched" "Detected in many" 8 "white matter: 85.7" "Region enriched" "Detected in many" 27 "spinal cord: 89.3" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 510000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB004597: AB_628352, HPA042426: AB_2677992" "unprognostic (1.41e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.64e-2)" "unprognostic (9.94e-2)" "unprognostic (8.10e-2)" "unprognostic (5.64e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-3)" "unprognostic (2.74e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.33e-4)" 216.7 1.2 15.4 5.2 19.6 10.6 26.8 13.8 13.0 2.1 5.0 58.1 2.2 26.8 1.6 6.0 2.5 10.4 167.9 12.2 24.5 0.7 0.3 1.3 1.1 22.3 25.3 4.1 22.8 35.7 14.3 0.2 19.9 9.0 8.7 7.5 46.5 5.7 77.2 2.9 3.3 251.4 21.7 0.3 8.6 8.7 28.0 3.6 27.0 214.6 4.0 3.5 5.8 20.0 0.1 0.0 3.1 0.2 0.2 1.3 0.3 0.1 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.2 0.8 0.1 0.1 0.4 0.8 0.1 0.4 0.3 0.0 0.2 1.7 0.0 0.0 0.9 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 2.4 0.0 0.0 0.0 0.9 0.0 0.2 0.0 2.5 0.7 0.0 0.0 0.2 1.3 0.0 7.0 0.0 0.0 2.8 0.2 0.2 2.6 0.1 0.4 1.1 2.2 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 19.6 13.8 13.0 12.2 24.5 22.3 25.3 19.9 21.7 28.0 20.0 57.0 0.0 1.1 37.2 0.7 0.3 0.1 0.2 2.2 1.3 0.8 1.8 9.1 0.0 0.7 3.7 56.3 0.1 0.5 0.0 0.0 0.2 40.8 0.3 0.8 9.4 9.0 0.0 9.7 0.0 0.0 84.2 0.5 0.3 0.0 5.9 0.4 0.2 0.1 1.7 12.7 0.0 0.0 0.0 0.3 7.2 0.9 2.7 1.8 6.5 0.0 2.2 0.0 60.3 24.0 0.0 0.0 43.6 0.3 1.0 0.0 0.8 0.2 1.9 493.0 78.9 116.9 14.5 2.1 0.6 1.0 0.0 2.1 1.2 0.0 0.0 THPO "MGDF, MPLLG, TPO" ENSG00000090534 Thrombopoietin P40225 3 184371935-184381968 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 35.4" "Cell type enhanced" "Detected in some" "Early spermatids: 2.3;Hepatocytes: 12.7;Late spermatids: 4.0;Proximal tubular cells: 9.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 6.0;Hep G2: 15.6;K-562: 2.8;RPMI-8226: 4.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 1070000 "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (5.57e-2)" "unprognostic (3.15e-2)" "unprognostic (1.75e-1)" "unprognostic (2.21e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (1.40e-3)" "unprognostic (4.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.25e-2)" 1.8 2.5 5.2 0.5 3.9 0.0 1.4 4.7 4.8 3.9 2.4 0.7 0.2 3.8 1.3 0.4 2.0 0.4 1.2 4.5 2.8 4.5 35.4 0.8 0.2 3.3 2.9 2.8 1.7 0.1 0.7 0.5 3.0 1.3 0.3 0.0 0.5 0.5 1.9 0.6 0.7 1.5 3.0 1.3 0.9 3.9 2.8 0.0 0.8 0.9 0.1 0.9 1.9 3.6 0.0 0.0 0.0 0.0 0.5 0.0 2.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 15.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.3 0.6 4.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 3.9 4.7 4.8 4.5 2.8 3.3 2.9 3.0 3.0 2.8 3.6 0.1 0.0 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 1.6 0.1 0.0 0.0 2.2 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 12.7 0.6 0.0 1.3 0.0 0.0 0.8 0.0 4.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 1.1 0.8 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 THRA "AR7, EAR-7.1/EAR-7.2, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRA3" ENSG00000126351 "Thyroid hormone receptor alpha" P10827 17 40058290-40093867 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 236.7" "Cell type enhanced" "Detected in many" "Muller glia cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009654, CAB023349" Approved Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB023349: AB_619577, HPA009654: AB_1854603" "unprognostic (2.75e-2)" "unprognostic (2.20e-1)" "unprognostic (6.64e-2)" "unprognostic (4.22e-2)" "unprognostic (8.78e-2)" "unprognostic (1.64e-1)" "unprognostic (3.41e-3)" "prognostic favorable (1.84e-4)" "unprognostic (1.47e-1)" "unprognostic (5.47e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-2)" "prognostic favorable (6.05e-8)" "unprognostic (3.05e-1)" "unprognostic (1.35e-1)" "unprognostic (4.21e-1)" "unprognostic (1.88e-3)" 40.7 43.7 199.1 12.0 236.7 23.0 38.9 159.3 218.3 67.5 108.5 67.2 31.1 49.9 22.0 19.1 57.7 25.8 63.8 189.7 181.8 34.1 10.2 32.2 9.7 162.4 172.1 90.7 31.3 29.9 50.0 17.1 149.4 34.5 18.8 35.4 27.3 35.5 90.7 50.2 36.2 34.6 166.5 13.9 48.0 18.7 183.6 12.8 32.6 52.8 6.3 45.0 45.9 179.9 4.9 37.6 11.5 28.9 77.4 28.2 4.2 19.3 23.0 19.6 18.2 31.5 27.2 5.6 31.3 37.6 8.7 11.4 22.6 11.7 10.6 2.1 21.6 10.4 44.5 13.4 26.0 16.9 11.2 45.1 9.5 18.4 7.1 45.4 26.6 16.7 21.2 5.2 16.5 7.1 22.8 27.4 10.6 24.6 11.8 32.1 22.7 27.6 6.4 3.3 19.5 17.7 14.8 23.3 33.7 17.5 27.3 19.5 18.7 19.4 18.9 17.7 5.9 11.9 9.0 3.4 12.0 19.1 10.6 0.2 0.3 1.9 2.0 0.1 0.8 0.2 0.8 1.2 0.3 0.4 1.4 1.7 1.1 2.1 0.3 0.6 1.0 0.7 199.1 236.7 159.3 218.3 189.7 181.8 162.4 172.1 149.4 166.5 183.6 179.9 32.2 19.2 7.3 27.1 6.2 10.6 28.1 3.3 31.3 76.4 19.6 21.2 45.4 38.6 2.7 33.1 20.9 0.8 16.5 37.9 50.9 12.3 1.1 20.5 29.5 20.8 25.1 17.9 19.1 14.8 1.4 36.8 29.0 12.1 14.0 23.1 24.7 13.8 11.6 62.2 24.2 22.6 6.1 10.6 5.1 2.7 51.6 8.6 19.6 8.4 5.1 95.2 37.0 15.6 26.5 6.9 14.6 49.7 3.9 17.2 58.8 29.9 7.5 22.5 19.7 84.7 44.4 0.3 27.3 14.6 10.4 0.3 18.1 16.3 39.9 13.8 THRB "ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2" ENSG00000151090 "Thyroid hormone receptor beta" P10828 3 24117153-24495756 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 199.2;Cone photoreceptor cells: 164.7;Excitatory neurons: 688.0;Inhibitory neurons: 631.3;Oligodendrocyte precursor cells: 329.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 7.7;basal ganglia: 15.1;cerebral cortex: 17.6;hippocampal formation: 18.5;white matter: 6.7" "Group enriched" "Detected in some" 5 "basophil: 7.2;naive B-cell: 2.2" "Group enriched" "Detected in many" 15 "B-cells: 2.2;granulocytes: 7.2" "Cell line enhanced" "Detected in many" "K-562: 45.6;RT4: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002008, CAB002009, HPA061035" Approved Supported "Nuclear bodies" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies" "CAB002008: , CAB002009: , HPA061035: AB_2684422" "unprognostic (1.82e-1)" "unprognostic (4.22e-1)" "unprognostic (2.83e-1)" "unprognostic (2.20e-6)" "unprognostic (3.37e-1)" "unprognostic (2.66e-2)" "unprognostic (1.93e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-3)" "unprognostic (2.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.46e-8)" "unprognostic (1.32e-3)" "unprognostic (6.75e-2)" "unprognostic (2.73e-2)" "unprognostic (3.34e-2)" 11.1 4.9 7.7 1.7 15.1 1.0 10.0 0.0 17.6 2.8 0.0 11.7 2.5 7.0 1.8 6.4 3.8 2.2 7.7 18.5 2.0 12.1 20.1 5.0 1.5 0.0 0.0 2.3 9.0 7.3 15.7 4.4 0.0 7.5 8.4 20.1 6.2 7.7 23.6 6.8 3.9 7.0 0.0 5.7 8.3 0.7 1.4 3.6 4.4 27.0 1.4 8.9 4.2 6.7 10.3 3.1 0.6 0.1 17.4 8.8 6.7 0.5 2.1 1.5 3.2 6.7 9.7 0.1 2.5 6.8 1.1 15.4 10.8 3.9 1.0 0.0 6.4 0.0 2.5 8.9 0.5 0.0 0.0 16.0 7.3 0.2 1.2 3.5 0.0 0.0 45.6 0.0 1.5 0.6 0.0 0.0 6.5 0.6 3.4 0.0 0.0 0.0 10.0 32.7 1.7 0.6 16.5 8.9 0.2 4.6 9.7 0.0 0.9 3.9 3.0 0.0 1.9 0.1 0.5 0.0 2.7 0.1 0.3 7.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 2.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.2 7.7 15.1 0.0 17.6 18.5 2.0 0.0 0.0 0.0 0.0 1.4 6.7 3.0 3.2 11.4 199.2 3.3 9.9 29.5 13.2 1.8 17.9 24.5 18.7 11.6 8.6 14.1 23.9 164.7 12.4 0.0 39.9 1.9 2.4 2.3 3.4 0.5 6.0 25.2 3.8 688.0 12.5 23.2 13.7 16.3 5.7 0.0 0.3 7.5 37.7 1.7 0.0 631.3 8.1 10.2 11.3 11.7 2.4 0.6 4.6 1.8 97.4 0.2 11.7 0.0 329.2 32.4 10.3 17.5 2.2 0.1 40.1 4.8 8.1 10.3 21.8 6.6 12.0 7.5 0.3 0.7 5.1 23.9 5.5 1.0 0.4 9.8 81.3 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 TIMM17A "TIM17, TIM17A" ENSG00000134375 "Translocase of inner mitochondrial membrane 17A" Q99595 1 201955503-201970664 "Cancer-related genes, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010083 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Mitochondria" "HPA010083: AB_10602899" "prognostic unfavorable (1.98e-5)" "unprognostic (3.28e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "unprognostic (1.80e-3)" "unprognostic (7.58e-2)" "unprognostic (4.15e-2)" "unprognostic (7.45e-2)" "unprognostic (1.64e-2)" "unprognostic (8.54e-3)" "unprognostic (2.02e-2)" "unprognostic (2.01e-1)" "unprognostic (6.45e-3)" "unprognostic (1.21e-1)" "unprognostic (1.44e-2)" "unprognostic (2.81e-1)" 31.4 48.3 29.3 35.4 30.6 36.8 29.3 31.2 35.8 27.4 34.9 35.2 31.4 25.7 41.1 31.9 20.9 19.0 72.2 31.3 32.5 42.2 80.6 23.7 30.9 30.2 30.6 18.5 23.4 55.8 24.8 31.3 31.0 25.0 38.0 33.3 23.0 28.4 86.1 20.9 23.9 35.3 30.5 24.9 29.1 19.7 30.7 30.3 38.2 94.9 35.8 42.8 23.2 29.4 89.1 88.9 78.5 94.9 64.5 67.2 132.5 138.4 98.0 110.5 98.4 104.8 89.7 122.5 49.7 118.6 81.1 69.2 145.3 82.4 118.3 90.4 90.7 67.7 119.1 99.7 66.7 145.5 69.5 78.0 89.8 113.2 93.9 79.5 117.4 75.4 173.1 66.7 131.7 56.9 78.9 78.3 99.6 88.3 47.0 76.5 91.4 152.6 136.2 83.1 118.0 83.2 84.6 213.5 130.7 98.7 118.5 97.0 95.2 73.6 78.7 86.7 146.4 99.9 115.9 102.3 78.4 109.2 84.2 18.5 32.0 29.2 21.7 44.5 28.6 30.3 23.5 28.1 50.1 23.6 22.4 26.2 7.7 29.7 46.7 33.6 37.0 32.2 29.3 30.6 31.2 35.8 31.3 32.5 30.2 30.6 31.0 30.5 30.7 29.4 31.7 38.5 37.2 9.4 54.7 92.2 100.2 123.3 34.1 24.1 43.2 36.2 129.5 37.1 73.0 38.6 35.5 115.2 44.2 38.8 137.0 94.5 69.7 40.1 55.2 46.0 34.0 36.6 18.1 86.0 187.0 55.9 40.2 48.1 55.2 37.9 32.9 168.0 114.8 35.3 17.4 58.1 81.4 44.0 177.7 32.0 33.5 52.8 53.4 4.7 80.4 49.4 26.8 6.6 14.9 109.4 30.4 38.4 98.6 85.0 37.2 131.8 55.8 31.7 26.3 46.6 75.3 42.6 61.5 60.6 98.9 265.6 46.2 62.9 58.3 118.1 TIMP1 "CLGI, EPO, TIMP" ENSG00000102265 "TIMP metallopeptidase inhibitor 1" P01033 X 47582408-47586789 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 2277.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 2325.3;Hepatic stellate cells: 2681.5;Langerhans cells: 2307.7;Leydig cells: 1776.0;Macrophages: 1705.0;Peritubular cells: 1561.7;Smooth muscle cells: 2043.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 3225.4;ASC TERT1: 4323.2;fHDF/TERT166: 2762.5;HSkMC: 2960.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022360, HPA053417" Approved Approved "Golgi apparatus" "Secreted to blood" NA NA 127000000 520000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "CAB022360: , HPA053417: AB_2682142" "unprognostic (5.86e-3)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.68e-2)" "unprognostic (1.81e-2)" "unprognostic (1.07e-3)" "unprognostic (4.99e-2)" "unprognostic (8.24e-3)" "unprognostic (9.12e-3)" "unprognostic (9.69e-2)" "unprognostic (9.10e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (2.90e-11)" "unprognostic (1.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (2.66e-1)" 1043.9 895.8 110.6 1713.4 110.5 122.2 253.0 114.1 329.6 630.5 160.0 228.0 68.3 342.1 237.4 130.8 570.2 1220.1 995.3 113.5 119.9 469.6 458.6 1221.2 150.4 132.9 125.2 820.8 170.1 224.1 510.7 589.3 130.1 749.1 204.0 25.9 518.6 412.7 61.8 132.4 180.0 741.1 118.9 239.9 208.9 267.7 286.5 80.3 340.0 78.9 119.7 2277.2 303.3 115.6 194.7 295.9 150.4 1850.9 3225.4 4323.2 36.4 2079.0 1728.4 632.5 514.0 118.9 360.1 1.8 269.6 2762.5 355.3 187.2 82.9 896.0 394.8 387.0 193.8 204.1 191.7 174.9 2097.2 136.6 2440.9 2960.8 227.7 1951.9 410.1 743.6 292.1 0.7 315.8 142.9 1088.6 343.1 2.5 518.0 166.8 229.8 647.9 2.5 318.3 173.8 1038.8 120.4 2.5 8.6 1243.6 8.2 276.9 277.6 15.3 257.6 284.8 943.7 1012.1 1108.3 206.3 58.8 135.0 7.4 2688.9 322.6 634.2 331.9 488.4 8.3 139.4 853.2 137.8 21.9 224.6 122.9 511.4 10.1 73.0 65.4 504.5 88.4 817.9 15.0 104.0 431.4 110.6 110.5 114.1 329.6 113.5 119.9 132.9 125.2 130.1 118.9 286.5 115.6 145.9 109.0 170.1 6.2 57.5 231.2 591.5 937.3 132.6 25.4 147.8 133.2 22.5 374.6 355.5 132.4 0.0 25.2 59.3 53.6 0.0 538.6 21.6 34.7 511.9 772.1 277.2 102.7 0.4 411.3 280.1 2325.3 53.5 66.7 491.4 163.7 2681.5 345.1 329.7 0.0 0.4 73.0 297.0 741.4 2307.7 86.9 1776.0 1705.0 512.3 6.5 289.0 141.7 73.2 8.5 0.6 802.1 42.4 1561.7 257.4 741.4 1.1 12.9 109.1 8.4 690.2 304.1 2043.5 52.8 10.6 25.8 174.7 45.0 126.5 231.9 50.5 513.7 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1663.5;Fibroblasts: 967.5;Leydig cells: 1398.6;Peritubular cells: 1934.1;Sertoli cells: 2327.1;Smooth muscle cells: 1116.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 502.6;BJ: 1173.0;BJ hTERT+: 514.7;fHDF/TERT166: 1073.7;WM-115: 893.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (4.98e-2)" "unprognostic (1.77e-3)" "unprognostic (1.60e-1)" "unprognostic (8.53e-4)" "unprognostic (1.67e-2)" "unprognostic (1.05e-2)" "unprognostic (7.01e-2)" "unprognostic (3.22e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (1.90e-5)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.66e-3)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (3.11e-2)" 805.5 288.7 71.7 41.4 74.9 1.1 556.9 68.7 72.6 376.1 221.0 190.4 30.5 393.3 230.4 168.1 373.9 153.5 532.8 64.3 79.2 248.0 92.0 625.1 69.5 83.2 86.7 116.2 81.1 139.5 139.1 999.5 76.0 178.8 81.2 31.7 178.7 341.1 128.1 170.3 122.1 379.6 70.3 187.2 152.1 64.1 106.2 41.1 340.1 325.9 28.8 197.4 261.1 59.5 19.6 0.0 16.9 2.7 502.6 280.6 1.0 1173.0 514.7 94.1 110.8 20.5 0.3 0.1 28.1 1073.7 3.6 18.3 3.2 48.4 135.0 0.1 14.3 147.4 23.5 52.4 197.4 0.1 59.7 47.4 120.4 166.9 9.5 3.4 0.0 0.0 0.1 0.9 44.6 1.2 0.4 5.0 2.5 0.0 0.8 0.1 3.4 0.4 2.1 97.0 12.5 16.8 24.1 0.5 322.9 266.6 0.7 1.3 0.0 7.9 25.2 245.9 19.1 0.2 0.4 0.4 232.3 0.2 893.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.7 74.9 68.7 72.6 64.3 79.2 83.2 86.7 76.0 70.3 106.2 59.5 1663.5 365.4 35.9 101.9 5.3 77.4 766.2 49.5 10.2 4.0 31.2 177.2 279.9 14.3 22.2 51.5 4.2 492.2 4.6 0.3 3.9 2.5 14.9 27.9 747.6 677.3 1.8 35.3 26.1 0.7 433.7 967.5 21.4 23.9 89.2 11.4 743.9 102.0 109.2 3.3 15.7 0.0 24.4 39.3 95.0 57.7 1398.6 28.6 76.5 116.2 0.7 146.6 0.0 52.3 0.8 0.9 0.0 1934.1 9.5 159.5 0.0 15.5 8.5 5.5 2327.1 339.2 1116.6 6.2 7.0 14.3 56.4 809.0 21.5 4.8 0.7 163.4 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 237.5" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 44.4 14.9 35.1 11.6 45.3 12.0 30.2 44.5 42.6 16.9 25.7 39.0 54.4 19.8 13.1 45.8 23.8 24.4 35.8 38.0 45.4 44.7 64.8 47.6 9.7 52.6 39.9 37.0 21.9 57.9 5.3 18.4 52.6 24.8 35.1 122.0 37.1 21.9 14.1 35.0 49.6 16.1 55.0 5.7 58.3 32.1 39.9 32.5 44.9 15.1 23.1 55.3 22.3 66.3 237.5 6.4 24.4 25.8 92.9 90.3 108.5 37.3 26.7 54.9 29.0 31.8 106.6 33.0 37.0 20.3 31.4 158.3 33.2 79.3 75.9 115.3 20.7 34.5 22.5 165.2 28.9 13.8 59.1 71.3 65.2 43.1 32.4 19.6 143.6 9.9 19.7 24.7 34.3 36.0 5.5 2.3 49.5 194.5 50.0 23.1 26.9 2.9 192.0 194.2 8.3 14.9 13.3 111.2 3.4 55.7 37.0 7.9 196.3 44.3 48.3 32.4 38.6 23.0 5.2 0.9 48.0 19.6 16.1 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.8 0.1 35.1 45.3 44.5 42.6 38.0 45.4 52.6 39.9 52.6 55.0 39.9 66.3 2.9 44.8 22.8 76.4 2.3 65.1 79.1 26.3 4.6 212.4 4.6 1.3 38.5 40.0 33.1 3.7 35.5 27.9 2.7 74.4 0.0 32.5 3.5 7.1 1.7 36.4 11.5 10.5 10.1 24.3 25.6 15.5 64.2 9.9 5.7 0.2 27.5 104.9 5.6 18.5 13.4 45.0 36.7 14.6 28.9 6.7 29.2 8.2 28.4 22.5 9.0 111.1 1.0 21.6 82.5 44.2 65.8 13.9 5.2 115.4 73.4 1.9 51.3 267.6 0.0 4.9 13.1 19.6 18.0 40.6 64.1 43.2 3.2 0.2 50.3 244.5 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174091-78187233 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Erythroid cells: 108.6;Extravillous trophoblasts: 210.4;Hofbauer cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 34.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in some" "white matter: 3.6" "Low region specificity" "Detected in many" CAB004683 Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (6.87e-4)" "prognostic unfavorable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 3.7 2.7 2.5 20.4 3.4 77.9 5.9 3.6 3.4 5.9 1.3 24.4 18.0 3.0 0.2 27.2 4.9 3.4 2.8 2.7 2.4 11.0 9.2 9.1 34.8 3.4 3.3 1.3 5.6 0.6 0.6 14.8 3.3 3.4 15.7 0.1 6.3 1.5 5.5 14.2 18.3 10.1 2.6 12.4 17.9 3.1 3.8 25.1 2.0 1.6 30.6 5.5 9.0 4.4 443.9 357.7 68.2 92.5 7.6 28.0 47.3 207.6 113.2 323.1 442.3 324.2 178.7 144.1 72.9 131.7 133.9 204.2 63.4 187.1 158.0 51.2 230.4 252.5 119.9 213.3 2.2 107.1 162.9 13.8 7.1 166.1 22.5 22.3 137.9 49.4 156.7 311.9 130.8 352.0 56.0 68.6 36.7 259.1 240.9 152.6 276.4 324.1 90.6 138.5 33.6 94.2 162.0 481.2 59.7 59.4 303.9 156.1 57.8 302.3 305.7 219.9 292.1 132.5 71.4 181.9 149.0 71.9 142.1 0.0 1.1 0.0 1.8 2.1 0.7 5.8 7.9 4.0 3.4 1.7 0.4 2.2 1.8 10.8 1.7 1.1 34.0 5.5 2.5 3.4 3.6 3.4 2.7 2.4 3.4 3.3 3.3 2.6 3.8 4.4 1.6 0.0 2.7 0.0 17.1 28.4 13.3 17.8 2.2 0.0 10.6 9.4 0.9 2.8 8.3 12.9 0.0 92.8 3.6 35.0 7.9 7.7 3.0 9.2 3.3 10.6 5.4 108.6 0.3 11.2 210.4 15.7 19.4 7.0 0.0 15.9 7.5 10.5 65.2 0.0 0.2 32.7 8.2 15.5 19.1 6.8 0.6 10.9 3.6 0.0 5.7 0.0 3.1 0.0 1.0 9.6 7.5 0.7 53.6 4.9 3.1 17.5 5.8 0.0 0.0 1.7 20.1 3.8 16.8 24.7 11.2 51.0 8.7 1.7 60.8 24.0 TLX1 "HOX11, TCL3" ENSG00000107807 "T cell leukemia homeobox 1" P31314 10 101131300-101137789 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "lymphoid tissue: 43.9;salivary gland: 16.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;HEK 293: 2.5;K-562: 13.8;SCLC-21H: 2.2;SH-SY5Y: 3.3;SiHa: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.06e-5)" "unprognostic (1.06e-1)" "unprognostic (1.60e-1)" "unprognostic (5.07e-1)" "unprognostic (1.57e-2)" "unprognostic (2.12e-2)" "unprognostic (2.69e-2)" "unprognostic (2.52e-3)" "unprognostic (1.81e-1)" "unprognostic (2.63e-1)" "unprognostic (3.26e-1)" "unprognostic (3.06e-1)" "unprognostic (7.35e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.1 0.3 0.0 0.1 0.7 0.0 0.1 0.0 16.5 0.0 0.0 0.0 0.8 0.0 0.0 43.9 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 5.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 3.3 2.7 0.0 0.0 0.2 0.1 0.4 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 TLX3 "HOX11L2, RNX" ENSG00000164438 "T cell leukemia homeobox 3" O43711 5 171309248-171312139 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "brain: 9.0" "Cell type enriched" "Detected in some" 6 "Extravillous trophoblasts: 7.7" "Cancer enhanced" "Detected in some" "cervical cancer: 1.7" "Group enriched" "Detected in many" 6 "cerebellum: 9.0;medulla oblongata: 2.3;spinal cord: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 25.9" "Region enriched" "Detected in single" 7 "cerebellum: 2.2" "Region enriched" "Detected in some" 8 "cerebellum: 15.5" "HPA030504, HPA060957, HPA069359" Enhanced Enhanced Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA030504: AB_2732458, HPA060957: AB_2732655, HPA069359: AB_2732130" "unprognostic (3.52e-2)" "unprognostic (2.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (2.76e-2)" "unprognostic (4.48e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.4 0.0 0.0 2.3 0.6 1.0 5.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 TMEM127 "FLJ20507, FLJ22257" ENSG00000135956 "Transmembrane protein 127" O75204 2 96248514-96265997 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.15e-3)" "unprognostic (2.67e-1)" "unprognostic (1.72e-2)" "unprognostic (6.51e-2)" "unprognostic (5.82e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (6.59e-4)" "unprognostic (6.73e-2)" "unprognostic (4.25e-1)" "unprognostic (1.06e-2)" "unprognostic (7.50e-2)" "unprognostic (2.17e-1)" "prognostic favorable (6.69e-5)" "unprognostic (3.59e-1)" "unprognostic (1.52e-1)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" 29.3 34.6 25.9 28.5 24.6 53.0 25.6 20.1 30.6 30.7 15.7 34.4 32.6 30.0 21.4 40.0 25.2 32.3 67.8 26.7 23.6 29.5 35.4 31.6 21.4 24.5 26.3 31.9 28.5 73.1 29.4 26.8 24.5 26.1 30.5 27.6 39.7 42.4 25.9 33.0 34.7 35.1 21.1 34.7 27.8 10.2 29.7 19.1 26.2 30.6 25.4 38.6 27.8 21.9 28.8 38.0 19.9 30.7 86.0 43.3 36.7 36.9 65.9 38.6 35.2 37.9 40.0 17.9 52.8 73.3 67.8 45.1 23.1 34.2 26.8 36.1 17.8 31.2 17.6 37.5 55.4 26.7 54.0 52.7 48.0 48.0 35.3 51.4 44.5 12.1 19.5 37.6 39.8 32.8 17.6 16.8 27.3 33.9 40.4 16.4 25.0 26.9 42.9 48.7 22.3 23.4 27.1 63.8 31.3 40.2 23.6 28.2 52.5 63.9 36.2 55.9 25.8 28.2 29.6 14.1 42.6 30.9 34.7 3.9 6.3 8.2 2.8 6.6 3.0 1.8 2.1 3.0 4.3 1.9 1.6 2.2 14.3 1.5 5.3 2.5 1.6 3.2 25.9 24.6 20.1 30.6 26.7 23.6 24.5 26.3 24.5 21.1 29.7 21.9 24.8 19.2 15.3 7.2 13.4 17.2 16.6 14.5 12.0 22.1 20.0 12.8 39.6 22.8 20.2 27.6 27.1 11.4 19.3 88.2 15.6 29.7 5.2 16.4 15.1 23.1 16.3 9.0 12.9 34.8 13.1 16.7 14.8 28.8 13.9 13.6 29.6 35.7 37.7 21.9 15.7 26.7 12.2 59.8 33.2 5.8 13.7 34.0 16.0 5.6 41.9 7.8 15.5 8.0 6.6 41.0 35.1 17.0 13.0 23.1 43.9 13.3 15.7 16.9 6.6 18.5 19.4 9.1 2.9 12.6 23.3 24.2 14.3 15.9 18.6 34.1 TMF1 "ARA160, TMF" ENSG00000144747 "TATA element modulatory factor 1" P82094 3 69019827-69052339 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 508.1;Late spermatids: 544.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008729 Approved Supported "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA008729: AB_1080310" "unprognostic (2.71e-1)" "unprognostic (2.11e-2)" "unprognostic (8.02e-3)" "unprognostic (7.19e-2)" "unprognostic (2.74e-1)" "unprognostic (6.75e-3)" "unprognostic (6.73e-3)" "unprognostic (1.79e-1)" "unprognostic (4.62e-2)" "unprognostic (2.37e-2)" "unprognostic (1.08e-2)" "unprognostic (2.83e-2)" "unprognostic (1.50e-1)" "unprognostic (1.03e-2)" "unprognostic (1.80e-1)" "unprognostic (3.51e-2)" "unprognostic (1.01e-1)" 10.3 10.6 4.4 14.0 5.2 26.2 14.1 6.2 5.5 13.3 12.3 12.5 12.9 14.8 14.1 11.5 12.9 14.1 9.2 4.3 5.3 12.6 11.0 12.0 16.0 5.3 5.1 12.6 13.6 15.6 9.9 16.5 5.2 14.5 14.2 12.5 17.4 10.3 9.8 9.7 14.8 11.6 5.1 12.8 14.0 19.4 5.4 9.6 20.9 8.3 14.8 13.5 7.9 6.1 19.5 8.3 7.8 7.9 20.7 26.4 17.5 24.6 23.6 16.1 19.2 11.9 14.1 7.4 3.9 25.1 11.3 10.5 10.2 10.8 26.4 14.3 7.6 14.4 11.0 14.1 18.5 16.3 19.7 15.6 17.0 21.4 19.3 17.1 17.5 6.0 8.8 11.8 21.2 11.1 9.5 14.1 6.8 12.3 4.4 7.8 9.9 10.4 21.0 15.4 5.4 8.3 20.2 14.2 15.4 10.4 10.7 19.4 23.1 15.8 6.7 27.9 14.8 13.2 13.6 7.2 24.1 16.6 13.1 4.8 2.4 5.1 3.1 2.0 2.1 2.6 2.8 2.7 2.1 3.1 2.9 2.6 5.3 2.7 3.4 2.4 3.1 1.6 4.4 5.2 6.2 5.5 4.3 5.3 5.3 5.1 5.2 5.1 5.4 6.1 49.2 64.1 78.9 21.9 84.7 37.5 37.6 41.7 39.3 43.4 46.2 35.8 36.9 38.6 86.4 42.3 37.5 39.6 108.4 48.8 15.6 52.4 508.1 150.4 92.8 43.1 55.6 45.0 32.2 56.2 58.7 70.0 54.6 86.2 74.7 51.7 29.3 19.7 28.4 35.3 38.4 61.6 38.7 31.8 54.4 544.8 51.0 55.1 35.6 32.8 66.7 41.5 59.8 36.2 40.9 50.6 40.8 62.1 129.3 64.8 49.4 25.1 200.5 52.1 32.9 62.8 56.8 116.2 39.3 30.6 39.5 80.6 94.5 54.5 38.5 85.7 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TMPRSS3 "DFNB10, DFNB8" ENSG00000160183 "Transmembrane serine protease 3" P57727 21 42371887-42396091 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 23.7;stomach 1: 14.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 17.7;Cholangiocytes: 24.3;Ductal cells: 16.1;Endometrial ciliated cells: 17.1;Gastric mucus-secreting cells: 23.4;Ionocytes: 16.2;Muller glia cells: 20.4;Respiratory ciliated cells: 39.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.1" "Lineage enriched" "Detected in single" 6 "T-cells: 3.1" "Cell line enriched" "Detected in some" 4 "U-266/84: 274.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (8.47e-3)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.85e-1)" "unprognostic (2.45e-3)" "unprognostic (3.97e-2)" "unprognostic (1.43e-1)" "unprognostic (8.17e-2)" "unprognostic (9.62e-2)" "unprognostic (4.81e-2)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.66e-2)" "unprognostic (2.73e-1)" "unprognostic (8.00e-2)" "unprognostic (1.33e-1)" 0.5 0.3 3.8 0.2 4.0 0.1 8.7 4.0 3.7 6.3 2.0 0.2 1.3 0.7 0.0 0.2 23.7 8.6 0.0 3.4 4.1 2.4 0.5 3.4 0.5 4.9 4.7 0.0 3.0 0.0 1.5 0.2 3.7 0.4 0.1 3.9 9.2 0.4 0.1 0.1 1.1 0.0 3.5 0.4 14.5 0.0 4.7 0.9 2.9 0.0 0.4 1.0 0.0 2.7 4.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 32.9 0.0 66.2 26.5 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.6 0.0 14.0 0.0 1.5 3.5 0.0 0.0 1.0 0.4 0.0 0.0 0.0 2.8 1.5 0.0 0.0 33.9 1.6 0.0 0.0 3.2 0.3 0.1 0.0 1.7 0.0 0.2 0.7 274.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 3.1 0.0 1.7 1.8 0.0 0.0 0.3 0.9 0.3 0.0 0.5 0.0 0.8 0.5 3.8 4.0 4.0 3.7 3.4 4.1 4.9 4.7 3.7 3.5 4.7 2.7 0.1 12.8 3.7 2.3 0.4 0.3 2.3 8.1 0.0 0.2 17.7 9.9 0.6 24.3 10.8 7.3 0.0 0.0 0.1 1.4 5.9 16.1 1.4 17.1 0.4 0.2 0.0 2.7 0.0 13.8 0.1 1.3 23.4 5.2 0.0 0.2 0.4 0.0 0.1 0.0 0.0 2.0 16.2 0.0 0.5 0.6 0.3 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.1 11.8 1.4 0.0 0.4 2.4 2.9 0.0 39.8 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.1 2.5 5.0 TNC "DFNA56, HXB, MGC167029, TN" ENSG00000041982 "Tenascin C" P24821 9 115019575-115118257 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 376.2" "Cell type enhanced" "Detected in many" "Astrocytes: 160.3;Basal prostatic cells: 72.1;Basal respiratory cells: 150.6;Basal squamous epithelial cells: 126.3;Prostatic glandular cells: 69.2;Smooth muscle cells: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 798.5;hTEC/SVTERT24-B: 634.4;U-138 MG: 526.0;U-251 MG: 484.5;U-87 MG: 711.8;WM-115: 1253.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004592, HPA004823" Approved "Secreted to extracellular matrix" NA NA 560000000 840000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB004592: AB_628342, HPA004823: AB_1080243" "unprognostic (5.46e-2)" "unprognostic (3.76e-2)" "unprognostic (7.57e-2)" "unprognostic (1.69e-1)" "unprognostic (9.20e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (7.86e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-2)" "unprognostic (1.82e-1)" "unprognostic (4.87e-3)" "unprognostic (1.79e-2)" "unprognostic (1.92e-2)" "unprognostic (7.60e-2)" "unprognostic (1.97e-3)" 61.0 4.7 16.4 170.4 28.5 0.9 41.2 14.0 9.8 43.6 3.0 174.3 16.7 106.8 12.2 23.9 25.5 14.1 32.6 15.6 34.3 82.0 7.7 54.2 39.8 20.3 43.8 5.3 4.8 2.3 7.2 4.0 28.0 39.1 28.3 4.8 19.8 33.3 6.2 25.9 56.5 376.2 15.0 40.8 62.4 4.8 65.4 17.1 13.3 3.2 22.6 96.7 15.9 20.5 25.1 6.0 6.9 1.3 37.5 10.1 0.1 205.7 798.5 425.4 203.6 5.3 55.3 0.0 32.8 291.7 6.9 89.9 0.0 12.0 241.3 0.4 2.2 0.0 4.8 0.0 0.7 0.4 3.9 6.2 1.7 634.4 289.9 42.9 0.1 0.0 0.0 5.2 11.4 0.0 0.1 0.3 65.2 0.9 85.3 0.2 451.9 0.1 373.3 0.1 0.6 5.9 91.4 0.2 19.3 140.9 1.0 1.4 0.1 526.0 88.4 94.2 484.5 14.3 0.4 0.4 711.8 0.6 1253.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 16.4 28.5 14.0 9.8 15.6 34.3 20.3 43.8 28.0 15.0 65.4 20.5 0.7 12.8 43.5 160.3 0.4 12.1 72.1 150.6 126.3 0.1 9.3 33.3 1.4 0.0 14.8 1.8 0.0 1.1 0.3 0.0 0.0 25.8 15.4 6.7 47.8 11.1 0.0 0.0 7.0 4.5 0.6 19.0 0.0 24.9 2.5 0.5 6.1 0.0 1.2 0.0 0.9 0.0 0.0 0.6 4.7 18.4 3.4 0.9 5.4 1.9 0.1 1.3 0.0 4.0 0.8 3.9 0.0 0.4 0.3 69.2 0.0 0.3 3.5 0.2 0.0 1.3 58.9 0.4 0.2 4.8 4.5 1.0 2.6 0.1 0.1 5.8 TNF "DIF, TNF-alpha, TNFA, TNFSF2" ENSG00000232810 "Tumor necrosis factor" P01375 6 31575565-31578336 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 6.5" "Cell type enhanced" "Detected in many" "B-cells: 90.7;dendritic cells: 60.8;Langerhans cells: 72.7;Macrophages: 108.3;T-cells: 100.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 68.0" "Group enriched" "Detected in all" 5 "granulocytes: 20.8;monocytes: 68.0;T-cells: 36.6" "Group enriched" "Detected in some" 8 "HDLM-2: 103.7;NB-4: 214.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB078469 Supported "Secreted to blood" NA NA 10100 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "CAB078469: AB_908070" "unprognostic (1.93e-1)" "unprognostic (1.07e-2)" "unprognostic (3.85e-2)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-2)" "unprognostic (1.67e-1)" "unprognostic (3.46e-1)" "unprognostic (1.19e-2)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-2)" "unprognostic (1.82e-1)" "unprognostic (9.85e-3)" "unprognostic (1.09e-1)" "unprognostic (2.04e-1)" 1.4 0.5 0.0 3.3 0.0 12.7 0.5 0.0 0.1 0.1 0.0 0.9 0.0 1.5 0.0 0.7 0.3 0.6 2.6 0.1 0.0 1.2 0.6 3.6 1.6 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 1.5 2.4 0.2 0.1 6.5 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.8 0.0 0.0 0.0 0.0 103.7 0.0 19.4 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 214.4 0.0 0.0 0.0 9.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 10.1 0.0 23.2 39.5 36.6 7.2 17.2 13.9 7.6 7.0 5.0 5.2 20.8 2.0 68.0 4.3 13.6 14.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 3.0 0.0 90.7 8.4 1.2 12.1 4.6 0.2 17.4 20.4 2.0 2.8 4.0 0.0 2.1 0.9 60.8 0.5 0.0 7.4 0.1 15.5 5.9 10.7 0.0 0.0 0.0 3.3 1.7 2.0 1.5 30.5 12.6 0.0 1.8 0.1 36.5 0.0 0.0 0.4 10.2 14.1 72.7 0.0 0.3 108.3 5.4 1.9 3.4 0.1 2.1 0.0 0.1 14.3 0.0 0.0 10.4 1.7 0.0 0.1 3.0 0.2 0.0 0.6 4.0 0.0 0.0 1.3 4.1 1.1 100.0 0.0 0.4 0.3 TNFAIP2 "B94, EXOC3L3" ENSG00000185215 "TNF alpha induced protein 2" Q03169 14 103121476-103137439 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 277.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 295.5;Langerhans cells: 198.7;monocytes: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 48.4" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "RT4: 785.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB004598, HPA030624" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Cytosol" "Nucleoplasm, Nuclear membrane" "CAB004598: AB_628370, HPA030624: AB_2673552" "unprognostic (5.01e-3)" "unprognostic (4.93e-2)" "unprognostic (1.56e-3)" "unprognostic (8.02e-3)" "unprognostic (3.39e-2)" "unprognostic (2.98e-2)" "unprognostic (5.52e-3)" "unprognostic (5.97e-2)" "unprognostic (1.94e-1)" "unprognostic (7.02e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (4.10e-4)" "prognostic favorable (2.79e-5)" "unprognostic (1.75e-2)" "unprognostic (3.83e-2)" "prognostic favorable (7.17e-5)" 119.9 76.8 9.0 103.6 11.5 106.8 78.4 6.7 12.2 53.8 12.1 39.8 38.0 50.9 6.6 88.3 57.1 102.2 48.3 8.0 9.7 67.7 61.6 142.4 87.4 17.1 10.4 16.9 33.6 66.8 16.6 48.4 16.2 73.6 26.8 1.6 84.0 14.9 35.0 53.3 52.5 24.8 13.6 147.9 37.4 37.1 21.4 39.5 36.8 32.5 80.3 277.5 74.6 16.1 34.7 156.3 1.1 0.6 10.1 45.9 54.5 9.7 43.2 26.4 8.9 1.6 148.7 0.3 120.3 48.5 142.5 104.2 11.6 0.0 11.9 6.1 0.6 15.4 120.0 0.7 19.2 7.7 20.0 17.8 1.6 8.4 0.1 10.5 14.2 7.7 15.5 35.3 3.6 3.4 0.4 11.6 9.7 19.6 13.4 6.8 18.9 24.9 80.8 785.1 1.3 2.3 150.2 52.4 1.9 5.6 83.8 50.4 28.4 5.1 13.5 30.3 31.5 31.4 2.4 0.9 38.1 34.0 16.1 5.9 16.8 9.0 0.1 18.6 0.1 0.1 0.1 0.0 9.4 0.2 0.1 0.1 48.4 0.2 15.0 0.5 0.0 4.5 9.0 11.5 6.7 12.2 8.0 9.7 17.1 10.4 16.2 13.6 21.4 16.1 45.8 0.0 25.1 2.3 8.2 28.3 41.8 295.5 6.8 1.1 24.2 11.4 14.1 51.5 126.1 27.6 0.0 1.2 1.3 1.0 0.0 160.9 36.8 92.4 122.2 47.1 17.3 1.7 2.5 44.7 61.2 123.3 5.6 172.8 33.7 4.5 18.9 8.0 54.1 0.0 5.7 0.3 85.5 151.2 198.7 48.8 8.4 163.3 30.2 25.3 351.9 5.9 5.2 1.0 0.9 122.1 18.3 2.2 11.7 186.0 0.7 14.4 121.5 0.7 19.7 104.9 39.7 2.1 4.6 20.7 33.4 4.8 8.3 1.1 1.9 138.6 TNFAIP3 "A20, OTUD7C" ENSG00000118503 "TNF alpha induced protein 3" P21580 6 137867214-137883312 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Inflammatory response, Ubl conjugation pathway" "DNA-binding, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 519.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 774.9;Endometrial ciliated cells: 605.2;Glandular and luminal cells: 1498.3;Macrophages: 596.6;Suprabasal keratinocytes: 745.7;T-cells: 624.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 106.5;Karpas-707: 161.3;REH: 151.5;U-266/84: 131.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002116 Approved Approved Centrosome,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Centrosome, Cytosol" "HPA002116: AB_1858162" "unprognostic (5.50e-3)" "unprognostic (9.98e-3)" "unprognostic (3.06e-2)" "unprognostic (1.01e-2)" "unprognostic (4.01e-2)" "unprognostic (9.47e-2)" "unprognostic (5.01e-3)" "unprognostic (4.40e-2)" "unprognostic (2.92e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (6.06e-2)" "unprognostic (3.55e-3)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" 57.0 15.6 4.4 114.6 3.8 519.5 23.3 2.9 23.9 27.5 12.0 22.6 21.4 31.3 5.2 26.6 23.4 47.8 23.0 3.2 2.8 13.8 27.4 56.2 76.8 6.1 3.9 73.2 25.8 25.8 7.5 28.9 6.7 17.3 24.7 19.1 16.1 10.3 8.6 50.5 30.7 33.5 6.6 46.1 22.8 8.3 9.5 71.1 11.7 3.8 55.7 171.1 14.6 6.2 32.6 4.8 1.8 2.8 10.1 16.9 7.8 18.8 67.6 4.8 5.7 34.9 8.8 7.3 43.1 20.0 106.5 22.6 1.1 50.4 8.9 46.8 2.2 7.5 19.8 21.1 11.2 10.3 12.8 15.6 7.3 56.4 53.6 5.6 2.9 21.2 17.4 161.3 8.4 1.8 56.2 41.4 1.5 2.1 1.4 151.5 39.4 6.1 14.8 15.1 0.7 0.3 3.6 5.3 16.9 7.0 3.4 11.7 14.8 46.9 6.8 46.0 9.6 48.7 131.4 14.0 16.9 13.1 6.1 7.3 12.6 9.6 19.6 9.3 27.9 7.4 19.4 18.0 14.3 7.8 13.1 10.1 13.6 11.1 5.1 26.2 19.2 14.8 4.4 3.8 2.9 23.9 3.2 2.8 6.1 3.9 6.7 6.6 9.5 6.2 71.8 38.5 76.3 2.0 94.5 774.9 150.2 102.1 384.7 1.1 29.0 42.3 4.6 25.8 53.7 0.0 29.2 8.1 395.5 53.9 1.9 60.0 2.6 605.2 365.9 114.8 11.9 5.2 0.1 26.9 104.8 110.1 111.1 1498.3 255.9 2.3 48.5 13.5 45.7 0.0 0.3 38.6 67.1 125.2 461.8 3.2 6.8 596.6 129.9 8.4 59.1 1.7 14.4 2.0 0.3 30.5 29.5 6.0 331.4 170.2 37.3 3.1 84.3 13.3 6.6 29.0 94.9 2.7 2.2 367.9 745.7 23.1 624.2 14.9 20.9 78.1 TNFRSF10A "Apo2, CD261, DR4, TRAILR-1, TRAILR1" ENSG00000104689 "TNF receptor superfamily member 10a" O00220 8 23190452-23225102 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050958, HPA054475" Approved Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA050958: AB_2681290, HPA054475: AB_2682500" "unprognostic (3.66e-1)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (4.89e-2)" "unprognostic (9.44e-2)" "unprognostic (8.39e-2)" "unprognostic (5.32e-2)" "unprognostic (2.18e-2)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (1.49e-1)" "unprognostic (1.99e-3)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-1)" "unprognostic (2.87e-1)" 5.7 2.3 2.6 9.9 2.5 9.3 5.7 2.2 2.7 4.3 2.2 7.0 6.2 2.9 1.1 8.4 4.1 8.2 3.0 2.0 2.4 3.8 5.3 6.6 13.4 3.4 2.8 0.8 2.4 2.7 0.8 7.1 3.1 2.9 7.1 0.2 4.8 2.5 1.5 4.9 6.5 3.9 2.8 6.8 6.5 0.5 3.4 6.4 3.0 2.8 14.0 10.8 5.8 2.8 18.7 33.0 1.7 0.1 1.2 6.4 0.1 3.8 2.3 1.9 5.2 25.4 31.8 42.9 41.9 2.4 9.1 34.6 29.5 47.2 3.1 10.7 0.2 22.7 20.4 14.7 16.2 12.3 20.7 11.0 38.2 41.1 35.0 5.5 21.9 1.4 35.7 14.9 8.9 14.5 0.4 7.8 22.6 33.0 20.0 0.3 0.0 31.2 24.4 39.5 0.9 1.1 9.3 23.0 0.0 6.9 12.3 9.3 31.3 0.1 0.2 1.8 0.1 17.4 26.7 32.7 0.2 3.9 0.5 2.8 6.1 5.7 5.0 2.6 13.8 15.3 16.1 10.2 6.3 19.1 15.7 9.2 0.6 6.1 2.6 0.0 20.8 6.5 2.6 2.5 2.2 2.7 2.0 2.4 3.4 2.8 3.1 2.8 3.4 2.8 21.5 3.2 8.7 0.7 22.3 23.6 20.7 9.1 21.6 0.2 8.2 7.1 1.1 7.2 15.5 11.0 0.0 0.1 3.1 10.1 0.0 10.1 0.1 8.6 1.9 16.6 2.4 1.3 0.4 4.0 0.4 2.2 10.2 23.9 7.6 0.7 2.9 5.1 3.1 0.0 0.4 7.0 8.2 2.2 12.7 0.0 0.0 8.5 3.6 9.4 4.2 0.0 2.1 1.0 0.5 20.3 7.3 0.0 14.0 11.7 4.5 2.9 5.7 0.0 0.0 0.9 1.1 0.0 0.5 25.6 27.4 0.0 12.8 0.1 9.1 27.4 TNFRSF10B "CD262, DR5, KILLER, TRAIL-R2, TRAILR2, TRICK2A, TRICKB" ENSG00000120889 "TNF receptor superfamily member 10b" O14763 8 23020133-23069031 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023625 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA023625: AB_1847860" "unprognostic (8.43e-3)" "unprognostic (7.43e-3)" "unprognostic (3.04e-2)" "unprognostic (4.94e-3)" "unprognostic (1.13e-1)" "unprognostic (7.74e-2)" "unprognostic (2.15e-1)" "unprognostic (9.51e-3)" "unprognostic (2.70e-1)" "unprognostic (2.82e-2)" "unprognostic (2.30e-3)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (4.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.86e-1)" "unprognostic (5.52e-2)" 20.7 21.8 4.4 17.1 4.0 13.9 16.8 3.7 4.2 10.7 19.5 14.7 22.0 11.1 6.8 10.4 13.5 23.9 14.0 4.8 3.9 15.1 34.7 22.9 14.9 4.7 4.8 17.8 21.9 19.6 6.5 13.6 4.4 12.2 21.7 1.1 13.2 10.7 10.6 6.9 25.0 16.2 4.8 17.4 14.1 5.1 5.9 8.3 16.8 4.8 16.7 31.1 9.5 4.7 39.0 98.4 144.6 46.5 71.7 93.7 143.0 91.2 123.5 50.7 77.6 40.9 39.1 23.1 59.1 52.4 88.4 37.2 39.3 179.7 90.4 22.9 31.2 0.0 43.6 85.4 238.0 9.6 37.5 136.1 164.6 110.5 121.1 131.9 160.4 27.5 16.1 0.2 104.5 12.3 0.8 14.3 37.0 52.6 34.6 21.0 53.5 14.8 100.2 62.7 0.2 24.2 46.4 14.0 51.1 101.6 23.1 9.9 145.3 71.8 36.4 23.2 66.6 27.4 4.7 10.8 74.6 17.8 106.6 3.8 17.8 0.6 1.9 12.6 3.0 4.0 2.4 2.0 15.8 1.9 4.7 1.9 3.6 1.2 17.5 0.0 1.6 7.8 4.4 4.0 3.7 4.2 4.8 3.9 4.7 4.8 4.4 4.8 5.9 4.7 41.8 12.8 35.6 8.1 17.6 31.6 35.0 55.9 34.7 0.8 31.7 26.7 3.7 12.8 36.4 12.9 0.0 4.2 10.4 28.4 3.9 29.1 1.3 42.2 16.8 39.4 0.0 4.0 3.3 26.5 8.8 18.8 60.6 81.9 9.5 17.1 18.9 27.1 9.8 0.0 1.1 20.8 14.2 21.3 69.6 2.3 7.2 33.1 19.6 38.4 15.5 2.6 1.0 15.1 0.6 50.7 22.6 6.8 5.1 37.7 36.4 9.2 18.7 0.3 0.0 15.4 14.3 0.3 2.1 25.3 18.2 4.2 14.3 21.0 26.0 53.1 TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102921-23117445 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.0;lymphoid tissue: 23.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 7.9;Endothelial cells: 5.3;Gastric mucus-secreting cells: 13.7;granulocytes: 8.8;Proximal enterocytes: 6.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 6 "neutrophil: 3195.8" "Lineage enriched" "Detected in many" 120 "granulocytes: 3195.8" "Group enriched" "Detected in many" 5 "BEWO: 108.8;HUVEC TERT2: 91.2" CAB025635 Enhanced NA NA 14600000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 60: Granulocytes - Receptor signaling" "CAB025635: " "unprognostic (2.63e-1)" "unprognostic (4.49e-3)" "unprognostic (7.21e-3)" "unprognostic (2.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-2)" "unprognostic (2.11e-3)" "unprognostic (5.56e-2)" "unprognostic (4.37e-2)" "unprognostic (8.98e-2)" "unprognostic (1.94e-3)" "unprognostic (2.74e-3)" "unprognostic (4.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.54e-2)" 8.3 1.8 1.2 23.8 1.0 21.0 1.0 0.9 2.4 4.1 1.7 2.8 2.0 1.1 0.7 2.2 4.7 12.7 1.6 0.7 1.0 2.6 2.6 7.5 1.6 1.6 1.2 0.5 2.5 1.8 1.1 8.3 1.6 1.8 3.0 0.1 1.1 1.5 0.5 0.4 2.4 3.1 1.4 18.4 2.6 0.8 1.6 2.9 3.6 7.2 1.3 6.9 0.4 1.3 0.7 3.6 1.3 3.4 0.0 0.7 108.8 4.4 0.0 0.3 0.4 0.0 4.1 0.2 1.4 3.9 0.3 0.6 0.2 0.4 0.2 4.4 1.1 0.4 1.1 1.2 11.2 0.5 2.0 12.1 0.8 2.0 0.8 1.6 91.2 0.2 0.0 0.0 0.8 3.2 0.0 2.6 4.2 0.2 0.1 0.2 0.1 0.0 19.4 0.4 0.0 0.2 0.2 0.2 1.0 9.7 14.7 0.6 18.0 1.0 2.3 3.3 0.3 3.4 1.3 0.0 4.9 0.9 1.7 57.8 26.7 511.0 0.1 14.4 0.3 1.4 0.5 0.1 6.0 0.4 0.6 0.3 3195.8 1.4 21.5 0.4 0.4 9.2 1.2 1.0 0.9 2.4 0.7 1.0 1.6 1.2 1.6 1.4 1.6 1.3 1.0 6.4 7.9 0.3 0.2 0.3 0.3 1.5 0.6 0.0 0.1 0.0 0.4 2.8 4.7 3.7 0.0 1.1 0.0 0.3 0.0 0.4 1.0 0.5 0.1 5.3 1.8 0.0 0.1 0.4 0.9 0.8 13.7 0.2 8.8 0.0 1.8 0.0 2.4 0.0 0.0 0.5 0.0 1.6 0.6 0.4 0.0 2.5 0.0 1.0 1.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 6.2 0.0 1.8 0.1 0.0 0.4 0.3 0.6 1.5 0.2 0.1 1.1 0.9 0.3 0.4 0.4 TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 114.4;Endothelial cells: 52.3;Gastric mucus-secreting cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;LHCN-M2: 250.4;WM-115: 238.4" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Actin filaments" "HPA070971: AB_2686330" "unprognostic (1.49e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.69e-1)" "unprognostic (7.06e-2)" "unprognostic (3.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" 10.6 2.3 4.8 5.3 4.8 9.0 4.8 4.5 6.1 3.7 6.1 6.1 4.4 4.7 3.7 2.6 5.9 7.9 6.2 4.4 4.6 12.1 17.6 10.0 3.5 4.9 4.7 7.1 3.5 1.9 2.8 2.9 5.1 4.6 7.3 0.5 2.2 2.9 1.4 2.1 6.9 7.7 5.2 5.0 5.5 3.0 6.1 1.8 3.8 1.0 4.1 3.9 3.1 5.0 15.1 12.7 16.3 9.4 12.2 47.7 0.3 78.2 29.5 5.8 7.9 24.4 12.2 0.0 16.1 47.1 0.0 5.0 13.7 68.6 50.3 0.1 12.1 4.2 7.7 21.2 52.7 2.7 5.3 60.1 75.0 20.6 14.0 71.4 99.5 0.6 0.0 0.1 250.4 0.0 0.0 8.2 13.2 44.1 0.1 3.0 0.1 3.8 19.0 6.8 0.3 0.1 8.4 0.0 0.0 36.1 0.1 9.9 59.4 0.1 0.0 4.7 0.1 0.0 0.0 0.0 63.3 4.0 238.4 2.5 2.1 0.9 0.0 0.8 0.1 1.3 1.9 0.6 2.9 0.4 5.2 2.1 1.4 0.2 1.4 0.0 0.6 1.5 4.8 4.8 4.5 6.1 4.4 4.6 4.9 4.7 5.1 5.2 6.1 5.0 114.4 0.0 9.8 0.3 7.0 5.0 4.1 11.3 14.8 0.0 6.0 12.8 3.5 1.5 10.2 1.8 0.0 0.1 1.2 6.8 0.0 5.7 0.4 6.4 5.8 52.3 1.8 0.0 0.1 2.2 0.3 19.2 83.6 9.5 7.6 1.5 16.1 8.2 2.9 0.0 0.1 5.6 6.1 6.1 9.8 0.1 0.3 13.0 8.8 19.7 3.5 0.3 0.0 0.5 0.1 12.3 3.1 0.4 6.8 4.9 6.8 2.8 6.4 0.2 0.0 11.9 14.3 0.8 2.3 4.5 2.4 0.1 5.9 2.1 6.9 3.7 TNFRSF11B "OCIF, OPG, TR1" ENSG00000164761 "TNF receptor superfamily member 11b" O00300 8 118923557-118951885 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 29.9;thyroid gland: 101.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 134.3;Collecting duct cells: 73.5;Ductal cells: 32.7;Proximal tubular cells: 117.3" "Cancer enhanced" "Detected in all" "renal cancer: 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 40 "dendritic cells: 3.9" "Group enriched" "Detected in many" 4 "BJ: 546.7;BJ hTERT+: 2013.0" "Low region specificity" "Detected in all" CAB034939 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "CAB034939: " "unprognostic (1.39e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (5.27e-2)" "unprognostic (2.33e-2)" "unprognostic (4.27e-3)" "unprognostic (1.10e-3)" "unprognostic (1.21e-3)" "unprognostic (5.50e-2)" "unprognostic (9.94e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (2.43e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.32e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (3.88e-4)" 3.3 3.3 2.6 5.3 3.1 0.0 2.6 2.6 4.1 1.1 3.5 2.5 1.4 10.2 0.5 0.4 1.4 5.8 9.4 2.5 2.7 29.9 14.2 9.4 7.0 5.0 3.0 0.3 1.8 0.5 1.8 4.9 3.3 1.6 3.5 0.3 1.4 1.0 0.4 0.5 2.2 2.6 3.1 2.6 1.2 0.1 3.0 1.3 101.8 0.8 2.9 10.7 0.3 3.8 0.0 0.9 8.6 0.0 27.5 5.3 0.0 546.7 2013.0 25.9 7.2 6.3 1.1 0.0 143.7 302.4 0.0 5.6 0.0 0.0 13.2 0.1 0.0 0.0 23.1 0.0 3.6 0.0 0.0 2.9 0.0 26.7 0.0 10.9 0.3 0.0 0.0 0.0 73.8 13.6 0.0 0.1 0.9 2.6 3.3 0.0 1.0 0.0 23.6 0.0 1.3 0.0 4.8 0.2 0.0 0.3 0.0 0.1 1.2 16.9 8.6 10.1 1.2 0.6 0.0 0.1 2.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 2.6 3.1 2.6 4.1 2.5 2.7 5.0 3.0 3.3 3.1 3.0 3.8 2.1 3.2 0.0 7.2 0.7 2.2 0.6 1.4 0.0 0.2 134.3 4.1 3.8 22.8 1.0 73.5 0.0 0.0 0.2 2.5 9.8 32.7 0.1 0.6 1.4 7.4 9.5 0.0 0.8 1.3 0.2 9.4 0.0 1.7 0.0 0.0 4.6 2.0 0.5 0.0 0.3 9.2 2.0 0.3 3.9 0.3 0.3 1.1 0.0 0.0 8.3 1.2 0.0 3.0 0.3 9.2 0.8 0.0 0.0 6.8 1.1 117.3 0.1 0.1 0.0 0.4 4.3 0.1 0.3 0.0 1.1 0.0 0.4 0.0 2.8 0.3 TNFRSF12A "CD266, FN14, TweakR" ENSG00000006327 "TNF receptor superfamily member 12A" Q9NP84 16 3018445-3022383 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 612.4;Basal prostatic cells: 1315.6;Basal respiratory cells: 622.2;Ductal cells: 938.2;Exocrine glandular cells: 698.4;Pancreatic endocrine cells: 1232.3;Prostatic glandular cells: 757.9;Urothelial cells: 695.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 139.6;neutrophil: 102.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 139.6" "Cell line enhanced" "Detected in many" "U-251 MG: 699.6" HPA007853 Approved Approved "Plasma membrane,Cytosol" NA Yes 370000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA007853: AB_1858463" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "unprognostic (8.90e-2)" "unprognostic (2.60e-1)" "unprognostic (4.06e-3)" "prognostic unfavorable (5.50e-4)" "unprognostic (7.04e-3)" "unprognostic (1.98e-3)" "unprognostic (4.17e-3)" "unprognostic (2.85e-1)" "unprognostic (5.02e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.98e-2)" "unprognostic (6.00e-2)" "unprognostic (2.80e-3)" "unprognostic (2.17e-2)" 42.0 45.9 5.3 27.0 5.2 8.3 24.4 6.1 9.9 12.5 9.4 26.5 37.5 34.8 1.2 17.6 19.0 55.2 108.3 5.6 8.8 133.5 61.0 72.6 2.4 8.2 7.9 8.2 116.3 56.1 59.3 33.0 7.0 33.4 4.5 4.8 48.4 17.1 58.5 18.1 21.6 32.5 7.4 6.7 42.6 5.4 10.4 5.2 37.0 9.3 3.1 73.8 13.9 7.0 217.6 155.6 17.7 31.9 31.0 71.3 109.1 444.3 277.5 316.2 205.5 70.1 336.0 1.5 566.2 270.4 401.3 224.2 4.2 283.4 132.2 8.3 11.2 1.5 52.4 58.4 205.1 3.7 15.2 65.2 196.7 345.1 433.5 298.1 100.9 0.6 24.5 2.4 362.7 394.0 0.6 28.3 85.5 88.7 369.6 1.9 207.1 7.8 355.8 37.6 19.9 7.3 314.7 127.9 255.8 57.7 69.4 5.8 192.2 601.9 303.2 423.8 699.6 6.6 2.9 3.1 190.0 18.9 488.8 12.2 11.4 139.6 6.1 7.3 7.9 0.2 2.8 4.9 14.6 0.2 1.4 2.7 102.9 8.0 4.7 0.6 3.4 4.0 5.3 5.2 6.1 9.9 5.6 8.8 8.2 7.9 7.0 7.4 10.4 7.0 16.9 102.5 37.7 0.3 6.9 612.4 1315.6 622.2 113.3 1.5 139.0 46.7 63.9 195.9 238.7 182.1 2.1 134.6 10.0 74.2 64.6 938.2 1.3 170.5 29.4 47.5 27.3 1.3 0.2 698.4 169.5 155.1 33.1 173.1 59.1 3.0 24.3 20.7 39.7 0.0 0.5 19.9 152.5 5.6 121.4 0.8 6.2 23.0 112.1 1.9 10.8 23.3 4.1 0.0 0.1 1232.3 155.3 6.8 5.3 757.9 52.9 118.0 118.4 5.9 6.6 190.5 228.6 10.9 9.4 35.5 359.7 189.1 25.3 1.3 50.0 695.6 TNFRSF14 "ATAR, CD270, HVEA, HVEM, LIGHTR, TR2" ENSG00000157873 "TNF receptor superfamily member 14" Q92956 1 2555639-2565382 "Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 16.2" "Low region specificity" "Detected in all" "HPA006404, CAB026150, CAB030007" Approved NA NA 110000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 63: NK-cells & T-cells - Immune response" "CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348" "prognostic favorable (4.39e-5)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "prognostic favorable (8.01e-6)" "unprognostic (1.11e-2)" "unprognostic (6.83e-3)" "unprognostic (9.62e-3)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (1.62e-1)" "unprognostic (2.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" "prognostic favorable (7.79e-6)" 37.0 71.8 2.4 6.2 2.2 5.0 34.8 2.2 6.6 52.5 3.9 57.6 16.9 32.9 1.2 26.4 39.9 4.4 23.8 2.7 2.4 57.1 61.8 58.0 10.0 2.6 2.3 33.0 20.4 3.9 24.4 2.8 2.4 50.4 5.5 0.6 35.3 2.3 6.5 22.2 67.5 1.2 2.1 100.7 45.9 7.5 2.7 2.8 29.4 1.0 4.0 33.6 37.3 2.6 0.6 0.3 0.3 8.7 2.3 9.1 2.7 2.5 8.5 4.9 6.5 0.7 6.3 2.4 0.5 7.7 2.8 4.4 0.0 3.2 0.7 11.4 0.0 6.1 0.8 1.0 9.1 3.3 6.8 4.4 2.6 2.6 0.6 4.3 5.8 0.4 1.9 11.9 4.5 0.0 4.4 0.3 0.1 2.4 4.4 2.8 0.0 0.6 0.4 3.7 0.1 0.2 0.0 0.4 16.2 0.0 1.5 0.7 5.9 0.3 1.8 0.8 0.4 8.1 2.2 1.2 0.5 2.7 1.5 2.2 31.4 5.5 40.2 68.2 23.3 42.4 47.2 27.0 23.2 50.1 51.3 39.4 78.4 12.8 50.9 33.2 62.8 39.3 2.4 2.2 2.2 6.6 2.7 2.4 2.6 2.3 2.4 2.1 2.7 2.6 63.7 19.2 38.0 5.5 97.6 16.4 31.2 50.3 23.3 1.5 36.0 33.8 8.3 47.1 51.5 35.0 0.0 1.2 90.9 94.7 3.9 16.8 0.3 19.9 18.4 52.7 36.1 18.7 8.8 32.9 1.5 27.1 77.5 25.8 53.2 8.3 41.4 20.0 88.8 0.0 0.9 78.4 22.4 80.1 59.3 2.6 20.8 91.3 46.2 17.8 106.1 15.9 131.8 2.5 1.3 24.6 115.8 13.9 70.4 29.8 219.6 35.5 34.7 0.7 19.7 9.0 22.0 0.1 0.4 15.6 13.4 1.2 84.4 16.0 101.4 44.3 TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.0;lymphoid tissue: 47.9;stomach 1: 24.4" "Cell type enriched" "Detected in some" 4 "Plasma cells: 449.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 124.9;naive B-cell: 108.5;plasmacytoid DC: 103.3" "Group enriched" "Detected in many" 63 "B-cells: 124.9;dendritic cells: 103.3" "Cell line enhanced" "Detected in some" "Karpas-707: 179.6;RPMI-8226: 296.0;U-266/70: 829.4;U-266/84: 453.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 2000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-5)" "unprognostic (3.41e-2)" "unprognostic (4.00e-3)" "unprognostic (1.41e-2)" "unprognostic (6.47e-2)" "prognostic favorable (1.58e-6)" "unprognostic (9.75e-3)" "unprognostic (5.93e-2)" "unprognostic (2.13e-2)" "unprognostic (7.96e-3)" "unprognostic (2.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.85e-6)" "unprognostic (2.06e-1)" "unprognostic (2.48e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" 0.4 1.1 0.0 14.9 0.3 1.9 14.1 0.4 0.4 1.4 0.0 28.9 29.0 0.5 0.2 1.9 0.6 3.1 0.4 0.2 0.3 0.3 1.0 2.0 31.9 0.3 0.0 0.8 0.5 0.1 0.1 0.1 0.3 0.4 22.1 0.1 15.4 0.9 0.0 0.3 15.2 0.6 0.0 20.3 24.4 2.2 0.3 14.8 0.7 0.1 47.9 9.9 0.3 0.6 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.8 0.3 0.1 0.0 0.0 49.2 0.1 0.3 0.1 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 179.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.6 0.0 296.0 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.1 0.0 0.6 0.0 0.5 0.5 0.0 0.5 829.4 453.4 68.1 0.7 0.2 0.0 1.2 0.4 0.2 0.3 0.1 0.4 124.9 0.2 0.2 0.2 108.5 0.1 0.2 1.8 0.7 0.1 103.3 0.1 12.6 0.0 0.3 0.4 0.4 0.2 0.3 0.3 0.0 0.3 0.0 0.3 0.6 0.0 0.0 0.0 0.0 91.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 10.9 0.0 0.0 0.7 0.0 5.3 0.1 0.0 0.0 0.4 2.0 0.0 0.0 0.4 1.8 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 106.7 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 449.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.7 0.6 0.0 0.6 0.0 6.0 0.0 1.0 0.0 TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 507.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" NA NA 17700 570000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010309: AB_2206639, HPA004102: AB_1846232" "unprognostic (2.19e-2)" "unprognostic (3.76e-2)" "unprognostic (8.14e-2)" "prognostic favorable (8.22e-4)" "unprognostic (3.07e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.50e-1)" "unprognostic (1.41e-3)" "unprognostic (1.00e-1)" "unprognostic (8.05e-2)" "unprognostic (4.78e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (5.14e-3)" "unprognostic (1.74e-1)" 166.5 133.3 33.7 76.7 34.4 42.4 120.0 35.3 38.6 105.0 47.8 114.1 101.5 111.8 23.0 105.6 106.7 88.8 80.6 32.4 40.3 94.5 176.5 130.7 38.1 45.7 40.4 90.6 57.3 53.7 57.3 82.4 39.6 86.9 56.4 3.5 76.0 46.3 91.0 103.7 109.5 97.5 40.4 111.3 84.4 22.6 39.7 39.2 97.4 63.1 36.1 113.2 113.2 37.4 40.2 296.4 40.9 60.2 277.7 282.0 75.7 82.2 143.0 108.2 93.9 34.7 153.6 3.7 28.9 179.3 85.6 107.1 12.9 96.4 74.1 0.8 25.3 20.3 79.2 82.2 245.5 104.4 66.9 291.8 94.4 90.2 131.4 250.4 134.1 42.0 33.7 29.8 126.3 57.1 34.0 100.0 102.1 146.1 87.6 27.9 66.6 32.4 83.7 70.7 0.1 2.1 117.8 60.9 62.5 103.6 16.4 111.4 146.0 84.6 71.7 64.7 78.4 0.1 10.6 12.8 100.5 95.9 107.0 17.1 165.8 93.5 62.2 130.4 60.0 0.5 25.1 51.0 123.7 0.4 22.3 34.0 507.2 9.7 111.5 31.6 26.2 117.3 33.7 34.4 35.3 38.6 32.4 40.3 45.7 40.4 39.6 40.4 39.7 37.4 102.0 51.3 37.1 15.3 4.8 123.0 115.8 127.3 81.4 0.4 50.1 35.9 9.3 67.2 70.8 27.6 0.0 62.0 35.5 204.0 15.6 98.7 1.2 25.5 66.5 111.8 33.6 30.1 4.6 119.4 120.2 109.3 43.8 42.3 7.6 27.6 159.2 145.0 176.4 0.0 1.3 56.8 32.6 146.7 113.4 5.4 102.2 102.4 71.2 32.8 127.1 15.9 104.0 11.1 0.9 116.6 239.4 65.8 4.2 141.2 227.5 96.9 30.8 0.7 124.9 64.1 89.4 1.3 1.1 57.0 134.7 148.6 31.2 21.5 57.4 140.1 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TNFRSF4 "ACT35, CD134, OX40, TXGP1L" ENSG00000186827 "TNF receptor superfamily member 4" P43489 1 1211340-1214153 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 10.3;lymphoid tissue: 13.3" "Cell type enhanced" "Detected in many" "Adipocytes: 112.3;Endothelial cells: 58.0;granulocytes: 67.4;Ionocytes: 40.7;Langerhans cells: 128.1;T-cells: 43.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 9.7;memory CD4 T-cell: 26.6;NK-cell: 14.7;T-reg: 35.3" "Group enriched" "Detected in many" 17 "granulocytes: 9.7;NK-cells: 14.7;T-cells: 35.3" "Group enriched" "Detected in some" 10 "MOLT-4: 6.2;NB-4: 12.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" CAB016128 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB016128: AB_626897" "unprognostic (2.24e-1)" "unprognostic (8.69e-3)" "unprognostic (1.36e-1)" "unprognostic (8.55e-3)" "unprognostic (1.02e-1)" "prognostic favorable (3.50e-6)" "prognostic unfavorable (6.03e-4)" "unprognostic (3.30e-1)" "unprognostic (1.48e-2)" "unprognostic (7.04e-3)" "unprognostic (1.04e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.52e-6)" "unprognostic (1.61e-1)" "unprognostic (5.46e-2)" "unprognostic (2.42e-1)" "unprognostic (5.91e-2)" 10.2 0.5 0.5 6.2 0.1 0.6 6.7 0.6 0.9 1.9 0.2 3.3 1.7 1.1 0.0 1.0 1.2 0.5 10.3 0.5 0.2 4.1 0.7 6.3 6.5 0.3 0.2 0.8 1.2 0.2 1.6 1.8 0.3 3.7 0.2 0.0 1.8 0.7 2.1 1.1 5.2 0.2 0.3 13.3 2.6 0.3 0.5 1.8 4.6 0.4 1.5 1.7 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.2 12.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.3 0.4 0.0 3.0 0.0 26.6 2.8 0.0 0.0 2.3 0.1 0.3 14.7 0.0 1.1 35.3 2.8 0.5 0.1 0.6 0.9 0.5 0.2 0.3 0.2 0.3 0.3 0.5 0.4 112.3 0.0 0.0 0.3 11.1 9.1 0.3 0.9 0.0 0.3 1.0 2.4 1.7 0.0 0.1 0.0 0.0 0.0 25.6 0.0 0.0 0.9 0.0 0.6 3.8 58.0 0.0 2.7 0.7 0.2 0.4 7.7 0.0 0.6 67.4 0.0 13.9 0.4 1.9 0.0 0.1 0.3 40.7 1.9 128.1 0.0 0.3 9.6 10.6 1.0 18.4 0.0 8.2 1.5 0.1 0.0 0.0 0.4 26.2 0.4 0.0 0.2 0.1 0.2 0.0 17.8 2.0 0.0 0.2 0.1 8.4 0.1 43.6 2.5 0.1 0.2 TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.3" "Cell type enhanced" "Detected in some" "Adipocytes: 7.1;Early spermatids: 3.5;Kupffer cells: 5.3;Langerhans cells: 3.3;Late spermatids: 9.8;Macrophages: 5.8;monocytes: 5.1" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 96.6" "Lineage enriched" "Detected in many" 5 "monocytes: 96.6" "Cell line enriched" "Detected in some" 21 "HDLM-2: 552.9" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" 5.3 0.0 0.1 3.1 2.3 0.6 3.5 0.0 0.6 0.2 0.1 0.4 0.0 0.8 0.0 0.2 0.9 0.6 1.9 0.0 0.2 0.3 0.0 0.9 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.7 0.2 0.2 0.1 0.0 0.3 0.1 0.9 0.9 0.7 0.5 0.1 1.4 2.5 1.4 0.7 1.0 0.1 1.2 1.1 0.9 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.4 0.0 0.1 0.8 11.7 0.0 0.0 0.0 0.0 0.0 0.1 552.9 0.1 0.0 0.1 0.0 0.0 10.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.7 26.3 1.5 0.0 0.0 1.5 0.2 21.7 0.0 0.4 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 1.4 1.4 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 17.6 1.0 0.1 59.4 0.3 0.1 0.1 0.0 8.7 0.0 0.0 0.0 18.3 0.0 96.6 2.3 0.8 8.5 0.1 2.3 0.0 0.6 0.0 0.2 0.2 0.1 0.2 0.1 0.7 0.2 7.1 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.1 0.5 2.2 0.0 0.0 0.6 0.0 0.2 1.1 2.6 0.1 0.0 0.1 2.2 0.1 1.5 0.0 0.5 0.0 0.0 5.3 3.3 9.8 0.3 5.8 0.0 1.0 5.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 1.0 0.0 0.1 0.3 0.4 0.2 0.0 0.1 TNFRSF9 "4-1BB, CD137, ILA" ENSG00000049249 "TNF receptor superfamily member 9" Q07011 1 7915871-7943165 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in some" "dendritic cells: 15.0;granulocytes: 63.4;Langerhans cells: 17.5;monocytes: 31.6;T-cells: 29.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "memory CD8 T-cell: 9.4;neutrophil: 7.8;NK-cell: 5.2;T-reg: 18.5" "Group enriched" "Detected in many" 5 "granulocytes: 7.8;NK-cells: 5.2;T-cells: 18.5" "Cell line enriched" "Detected in some" 9 "HDLM-2: 111.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA071425 Approved "Nucleoli,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Nucleoli "HPA071425: AB_2686394" "unprognostic (7.23e-2)" "unprognostic (1.72e-2)" "unprognostic (8.26e-3)" "unprognostic (1.32e-3)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-4)" "unprognostic (9.47e-3)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.69e-8)" "unprognostic (1.64e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (9.55e-2)" 0.5 0.2 0.4 3.9 0.4 2.2 0.2 1.1 0.5 0.2 0.3 0.5 0.5 0.3 0.2 0.6 0.1 1.6 0.2 0.4 0.1 0.2 0.7 0.8 9.0 0.3 0.1 0.2 0.7 0.0 0.0 0.2 0.3 0.3 1.1 0.5 0.3 0.2 0.2 0.5 0.8 0.2 0.0 4.1 0.8 0.2 0.3 3.7 0.2 0.2 9.9 1.9 0.0 1.1 2.5 0.9 0.2 0.2 0.0 0.1 0.1 0.1 0.4 0.5 0.5 3.1 0.5 0.1 1.2 0.1 1.8 0.4 0.0 0.4 1.9 111.5 0.2 0.6 0.5 0.1 1.8 0.0 0.9 0.3 0.7 0.5 0.2 0.4 0.1 0.1 0.4 0.3 0.1 0.2 0.0 0.3 0.1 0.1 0.2 0.1 0.7 0.2 0.3 0.1 0.2 0.2 0.4 0.2 0.0 1.3 0.1 0.3 0.3 0.3 3.2 0.1 0.5 0.2 0.2 0.2 13.0 0.8 0.1 1.5 1.9 0.2 1.7 0.6 0.3 0.3 1.1 9.4 1.4 0.4 0.2 1.7 7.8 5.2 0.1 0.3 18.5 1.4 0.4 0.4 1.1 0.5 0.4 0.1 0.3 0.1 0.3 0.0 0.3 1.1 0.6 0.0 1.7 0.0 1.6 0.3 0.9 0.3 0.6 0.0 0.3 0.5 0.4 0.0 1.9 0.0 0.0 0.0 15.0 0.1 0.0 1.3 0.0 0.6 1.0 0.8 0.0 0.0 0.2 1.1 0.0 1.0 3.6 1.4 63.4 0.0 0.0 0.0 0.8 0.0 0.3 0.2 0.0 0.3 17.5 0.0 0.0 3.6 5.4 0.0 31.6 0.0 1.0 0.0 0.1 2.0 0.1 0.0 9.4 0.5 0.0 0.1 0.0 0.0 0.0 7.7 1.0 0.4 0.1 0.1 0.4 0.0 29.2 0.0 0.5 0.3 TNFSF10 "Apo-2L, CD253, TL2, TRAIL" ENSG00000121858 "TNF superfamily member 10" P50591 3 172505508-172523475 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 732.8;Exocrine glandular cells: 424.6;Proximal tubular cells: 556.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 265.4;classical monocyte: 133.4;intermediate monocyte: 203.5;neutrophil: 257.1;non-classical monocyte: 213.2" "Group enriched" "Detected in all" 5 "granulocytes: 265.4;monocytes: 213.2" "Cell line enhanced" "Detected in many" "BEWO: 73.1;CAPAN-2: 53.7;HaCaT: 51.5;HMC-1: 244.5;RPTEC TERT1: 122.1" "Low region specificity" "Detected in all" HPA054938 Uncertain "Secreted to blood" NA NA 67400 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA054938: AB_2682643" "unprognostic (9.16e-2)" "unprognostic (2.79e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-3)" "unprognostic (2.52e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (1.32e-1)" "unprognostic (6.27e-2)" 51.0 49.9 9.5 55.4 9.8 14.8 84.5 9.8 17.0 37.3 17.3 76.8 100.3 47.1 19.6 66.4 39.1 45.3 31.7 9.0 9.9 145.1 209.0 177.2 54.7 12.0 10.2 27.1 22.2 77.7 10.4 167.9 11.0 86.7 91.4 1.4 127.9 42.7 20.7 54.6 95.2 26.3 11.0 70.9 47.3 4.8 10.3 34.2 29.3 61.7 46.8 70.3 62.4 10.6 12.4 0.6 0.1 0.2 8.2 6.6 73.1 0.0 0.5 3.7 5.9 0.3 53.7 7.9 34.7 0.0 3.2 51.5 0.3 6.3 0.7 19.6 0.2 0.2 1.5 1.1 0.4 14.7 244.5 8.2 8.0 1.3 0.2 0.0 25.6 1.6 0.3 8.7 0.0 0.1 1.9 19.4 0.3 0.2 0.5 2.9 0.2 3.5 122.1 4.6 0.3 0.5 27.2 1.0 0.6 0.4 15.3 8.0 1.1 0.1 0.2 0.1 0.7 9.3 1.1 9.5 0.6 8.0 0.2 265.4 133.4 14.7 10.9 203.5 15.0 16.7 30.4 16.8 49.1 18.2 21.6 8.5 257.1 49.3 213.2 2.9 36.8 73.6 9.5 9.8 9.8 17.0 9.0 9.9 12.0 10.2 11.0 11.0 10.3 10.6 326.5 70.5 114.4 0.0 26.2 22.0 169.5 398.4 69.4 0.3 146.5 97.3 7.9 84.4 281.1 66.2 0.0 6.6 20.7 294.2 45.0 732.8 4.5 60.5 18.2 247.5 48.3 9.7 0.1 424.6 189.4 69.2 44.9 121.0 257.0 2.4 186.7 75.2 23.5 1.7 0.1 111.3 175.0 79.8 23.7 3.8 18.3 70.5 7.2 52.5 160.3 18.7 52.5 0.0 0.1 244.0 216.4 4.9 23.2 82.7 317.0 556.7 114.5 1.5 0.0 6.5 22.3 0.1 0.3 103.1 25.6 10.9 51.8 19.7 74.3 170.1 TNFSF11 "CD254, ODF, OPGL, RANKL, TRANCE" ENSG00000120659 "TNF superfamily member 11" O14788 13 42562736-42608013 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Cytokine, Developmental protein, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.5;liver: 5.2;lymphoid tissue: 15.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 10.8;Breast myoepithelial cells: 5.1;Ductal cells: 6.2;Early spermatids: 8.0;Late spermatids: 15.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "NK-cell: 13.6" "Lineage enriched" "Detected in many" 7 "NK-cells: 13.6" "Cell line enhanced" "Detected in some" "HSkMC: 2.1;NTERA-2: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009193, HPA045142" Enhanced "Secreted to blood" NA NA 17200 "Cluster 15: NK-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 35: Glandular cells - Unknown function" "CAB009193: , HPA045142: AB_2679231" "unprognostic (3.97e-4)" "unprognostic (1.40e-1)" "unprognostic (9.01e-3)" "unprognostic (3.81e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (7.09e-2)" "unprognostic (7.70e-2)" "unprognostic (2.29e-1)" "unprognostic (1.25e-3)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (3.94e-5)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (5.46e-2)" "unprognostic (7.74e-2)" 0.2 0.0 0.0 4.8 0.0 0.2 4.5 0.0 0.1 0.8 0.2 0.9 0.4 0.1 0.0 0.1 0.0 1.4 0.1 0.0 0.1 0.1 5.2 0.1 15.2 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 1.1 0.0 0.1 1.9 0.0 0.0 0.6 0.5 1.3 0.1 1.5 0.0 0.1 5.0 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.0 0.0 10.8 5.1 0.4 1.5 0.2 0.0 0.0 0.0 2.3 0.0 0.0 6.2 8.0 0.5 0.1 0.1 1.2 0.0 0.2 0.2 0.0 0.2 0.0 0.7 0.0 0.3 0.0 1.0 0.0 0.0 0.7 0.9 0.0 0.0 0.4 15.3 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 3.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 0.0 0.3 0.0 1.8 0.0 0.0 0.0 TNFSF13 "APRIL, CD256" ENSG00000161955 "TNF superfamily member 13" O75888 17 7558292-7561608 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 141.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 10.4;Basal squamous epithelial cells: 8.0;Erythroid cells: 5.9;Gastric mucus-secreting cells: 11.2;Macrophages: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 438.1;intermediate monocyte: 420.9" "Group enriched" "Detected in all" 12 "dendritic cells: 283.5;granulocytes: 158.9;monocytes: 438.1" "Cell line enhanced" "Detected in many" "EFO-21: 43.6;RPMI-8226: 39.9;RPTEC TERT1: 110.6;U-937: 44.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004863 Uncertain "Secreted to blood" NA NA 6770000 35000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "HPA004863: AB_1078187" "unprognostic (2.46e-2)" "unprognostic (2.20e-1)" "unprognostic (3.42e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (3.57e-1)" "unprognostic (3.32e-2)" "unprognostic (3.70e-2)" "unprognostic (3.75e-1)" "unprognostic (1.15e-1)" "unprognostic (6.95e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.30e-9)" "unprognostic (4.69e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.38e-2)" 27.7 31.6 39.5 37.7 43.7 48.4 29.5 39.7 47.3 33.5 66.7 45.9 74.7 13.3 19.2 12.5 31.8 54.1 18.0 35.3 37.6 55.6 16.2 100.7 33.1 44.8 43.3 24.8 41.1 18.0 19.7 14.7 41.1 22.6 41.9 13.0 141.9 32.1 5.3 10.5 39.5 24.8 40.0 30.6 54.0 4.6 44.8 14.1 27.0 10.1 24.5 26.0 15.5 38.8 20.8 8.3 2.8 5.5 3.2 1.7 3.4 3.7 2.7 1.5 1.3 4.6 12.8 9.1 43.6 3.8 5.2 13.1 0.1 3.6 1.6 16.2 7.0 5.9 18.2 9.7 6.7 5.1 5.9 3.6 3.6 1.0 5.7 8.8 4.7 6.5 4.6 3.5 1.3 3.1 2.3 16.6 2.7 20.3 6.0 16.5 3.4 39.9 110.6 13.5 5.1 4.9 7.2 18.8 2.5 4.1 25.2 12.4 2.4 4.8 5.8 2.1 8.1 0.8 2.8 2.4 1.9 44.1 9.5 75.2 438.1 158.9 0.9 420.9 0.8 13.7 0.5 0.7 283.5 25.0 2.4 1.5 56.9 7.9 265.4 130.8 0.9 257.1 39.5 43.7 39.7 47.3 35.3 37.6 44.8 43.3 41.1 40.0 44.8 38.8 0.2 6.4 10.4 0.0 2.1 0.0 0.2 0.2 8.0 0.1 0.4 0.1 0.0 0.0 2.0 1.8 0.0 0.0 0.1 1.0 0.0 0.4 0.0 0.2 0.1 0.0 1.2 5.9 0.0 0.2 0.0 2.9 11.2 0.4 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 19.5 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.2 0.7 0.3 1.5 0.2 0.0 0.1 0.2 0.0 0.0 2.6 0.0 0.0 0.8 0.1 0.6 0.2 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNFSF4 "CD252, gp34, OX-40L, TXGP1" ENSG00000117586 "TNF superfamily member 4" P23510 1 173183731-173207331 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins" Cytokine "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Granulosa cells: 37.0;Macrophages: 26.4;monocytes: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 42.0;HHSteC: 17.3;HUVEC TERT2: 81.2;LHCN-M2: 67.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059579 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA059579: AB_2684071" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (4.58e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-2)" "unprognostic (1.74e-1)" "unprognostic (1.13e-3)" "unprognostic (2.13e-1)" "unprognostic (8.65e-2)" "unprognostic (5.17e-2)" "unprognostic (1.26e-2)" "unprognostic (1.18e-1)" "unprognostic (1.11e-7)" "unprognostic (3.73e-3)" "unprognostic (2.66e-1)" "unprognostic (9.49e-2)" "unprognostic (2.98e-2)" 1.2 2.0 1.1 2.3 1.2 0.6 0.6 1.8 1.5 1.0 0.1 1.0 0.3 0.8 0.5 0.6 0.9 1.1 1.0 1.1 0.9 0.8 0.9 1.2 2.2 1.2 1.2 1.1 1.1 0.5 1.5 0.5 1.2 1.4 1.2 1.4 0.4 0.6 0.2 0.3 0.8 0.8 0.8 1.7 0.7 4.0 1.1 3.7 0.4 0.2 1.9 1.5 0.8 1.2 0.1 0.0 0.4 1.2 2.7 14.1 0.2 4.1 0.9 0.2 0.3 0.2 0.1 0.2 0.7 42.0 0.2 0.1 0.1 0.1 0.3 0.7 0.1 0.1 0.4 1.6 17.3 0.3 0.2 6.2 0.3 2.1 0.3 1.3 81.2 1.5 0.1 0.5 67.5 0.0 0.7 0.4 0.3 0.1 0.6 2.0 0.1 0.6 0.6 0.1 0.1 0.6 0.3 0.2 0.9 1.3 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.9 1.4 0.3 0.2 7.7 4.4 0.0 0.1 0.1 0.5 0.0 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.4 0.7 1.7 0.0 1.2 0.4 2.8 1.1 1.2 1.8 1.5 1.1 0.9 1.2 1.2 1.2 0.8 1.1 1.2 0.2 0.0 0.5 8.5 0.8 0.8 0.3 0.4 0.6 0.4 0.2 0.0 1.5 1.5 0.1 1.8 0.0 0.2 2.2 0.9 0.0 0.1 5.8 0.2 0.4 1.0 0.0 0.8 3.6 0.0 0.2 3.7 0.0 0.1 0.0 37.0 0.0 1.2 0.5 0.0 5.2 0.0 0.0 0.6 2.3 2.2 0.3 26.4 1.8 0.0 8.2 1.3 2.1 2.5 4.0 0.3 0.1 1.9 0.4 0.4 0.0 0.2 0.8 0.5 0.0 0.6 3.7 0.3 0.2 0.0 0.6 0.0 2.4 0.7 0.1 0.1 TNFSF8 "CD153, CD30LG" ENSG00000106952 "TNF superfamily member 8" P32971 9 114893343-114930595 "Cancer-related genes, CD markers, Predicted membrane proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.7;lymphoid tissue: 26.9" "Cell type enhanced" "Detected in some" "B-cells: 8.2;dendritic cells: 6.5;Kupffer cells: 6.5;Macrophages: 8.4;Microglial cells: 5.6;monocytes: 5.4;Plasma cells: 9.3;T-cells: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Daudi: 50.9;SuSa: 23.3;U-698: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (8.82e-2)" "unprognostic (6.56e-3)" "unprognostic (7.79e-2)" "unprognostic (6.05e-2)" "unprognostic (2.67e-1)" "unprognostic (5.58e-3)" "unprognostic (5.26e-3)" "unprognostic (1.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.24e-1)" "unprognostic (1.70e-1)" "unprognostic (2.02e-1)" "unprognostic (4.75e-2)" "unprognostic (3.01e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-2)" "unprognostic (1.82e-1)" 3.3 1.4 0.5 13.9 0.7 18.7 2.0 0.5 0.7 1.9 0.9 2.0 0.7 0.8 1.8 1.7 0.8 5.0 0.9 0.4 0.6 0.8 2.2 2.5 23.4 1.1 0.6 0.7 0.8 0.4 0.2 2.8 0.8 0.6 2.4 0.0 0.6 0.6 0.2 0.4 5.1 1.7 0.8 7.4 2.5 0.3 1.5 26.9 0.8 0.4 22.2 5.9 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 40.8 0.0 0.0 0.0 0.0 20.8 0.0 6.0 10.1 19.8 1.8 23.7 14.1 10.7 2.4 26.2 19.6 6.2 1.8 1.4 6.5 9.8 13.0 0.5 0.7 0.5 0.7 0.4 0.6 1.1 0.6 0.8 0.8 1.5 1.4 0.2 0.0 0.0 0.0 8.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.5 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.4 0.1 0.0 0.0 0.5 1.1 0.0 1.3 0.0 0.7 0.1 3.7 0.0 0.1 0.0 0.0 6.5 4.8 0.0 0.0 8.4 0.0 5.6 5.4 0.0 2.1 0.0 0.1 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.6 0.0 29.3 0.0 0.0 0.0 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 99.3;Oligodendrocyte precursor cells: 245.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041954, HPA069561" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Vesicles "HPA041954: AB_10794164, HPA069561: " "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 14.2 10.0 77.1 24.7 64.1 72.2 15.0 40.0 102.9 18.0 11.8 18.5 9.4 13.8 11.1 19.1 17.1 10.5 18.4 75.6 51.4 7.7 10.5 14.1 30.0 77.5 59.8 13.4 12.1 6.1 36.4 12.7 70.1 21.1 6.3 9.3 26.3 11.8 54.8 62.3 16.1 9.2 45.5 27.0 19.7 12.0 57.0 16.0 10.0 16.7 20.1 19.4 19.3 60.6 93.4 16.3 15.4 13.4 15.3 11.5 80.0 17.7 16.7 11.7 9.4 15.6 79.3 25.9 55.1 24.2 17.4 34.1 14.9 22.2 3.5 61.8 15.4 22.0 36.2 10.4 7.9 13.5 10.2 7.8 30.7 11.7 17.9 26.7 13.3 9.2 11.3 30.6 9.4 67.1 5.3 39.7 12.3 24.6 29.1 13.8 15.6 26.0 7.2 51.2 16.2 16.5 9.5 37.6 21.3 11.3 71.4 11.9 18.9 19.1 13.0 11.4 48.6 70.8 9.2 17.0 22.1 38.0 15.4 1.4 1.2 0.3 0.9 1.5 0.4 1.3 0.8 0.4 0.5 2.5 0.5 0.5 2.7 0.4 1.4 1.5 0.1 0.7 77.1 64.1 40.0 102.9 75.6 51.4 77.5 59.8 70.1 45.5 57.0 60.6 9.3 6.4 7.7 44.4 14.6 6.9 8.1 6.0 4.6 30.6 13.0 12.6 16.1 7.2 8.9 0.0 50.1 13.4 11.0 18.0 1.9 4.0 1.0 4.1 5.4 11.1 6.1 12.8 42.7 5.3 3.3 4.6 14.3 4.1 1.3 4.5 11.7 19.2 8.1 99.3 45.3 2.3 6.1 16.0 11.7 1.2 6.5 13.7 5.4 20.6 16.2 5.9 21.6 245.3 25.1 29.5 9.6 6.4 10.7 8.2 0.9 1.6 7.6 20.3 0.0 4.8 5.7 6.4 11.2 11.0 10.5 4.2 12.5 1.7 6.4 19.0 TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 213.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" 34.7 47.8 20.8 17.0 19.4 60.8 32.1 19.9 25.8 43.6 23.6 22.7 29.1 26.6 12.7 76.5 26.8 24.9 43.2 19.8 26.6 32.7 49.0 37.1 15.3 30.2 24.5 21.5 20.2 48.5 37.4 27.7 32.9 23.2 9.8 5.9 60.6 11.7 213.8 74.9 28.4 10.8 19.6 23.9 20.8 25.9 24.8 13.1 26.5 68.6 12.7 19.5 45.0 22.1 15.8 15.3 8.8 14.3 58.3 34.9 42.3 15.5 43.8 28.4 31.1 21.5 14.3 6.2 28.0 45.4 18.3 7.3 8.6 15.6 9.9 18.7 21.3 5.3 17.1 43.8 58.6 10.8 23.6 49.8 19.2 39.6 13.3 18.5 19.8 11.6 10.3 15.3 14.1 13.8 8.2 27.5 7.0 18.9 8.6 14.9 12.3 13.2 10.9 11.3 14.9 12.1 34.1 34.8 34.5 7.3 18.0 16.7 22.0 34.0 29.4 27.3 7.7 18.0 12.4 16.7 45.7 10.5 11.4 18.6 100.9 44.5 19.3 60.7 15.6 13.6 29.5 18.4 48.0 11.0 22.6 15.7 129.1 15.1 66.2 25.9 48.2 63.3 20.8 19.4 19.9 25.8 19.8 26.6 30.2 24.5 32.9 19.6 24.8 22.1 10.1 22.4 36.9 8.8 12.7 12.7 10.3 29.5 7.4 11.1 19.1 11.0 23.2 15.7 33.0 12.9 12.5 64.6 13.8 41.6 27.4 40.9 29.9 32.0 17.8 14.2 16.2 9.7 9.3 38.9 57.1 22.6 15.3 48.0 22.8 10.4 16.1 34.0 60.8 11.8 15.2 18.1 50.8 33.5 35.2 21.4 11.5 45.2 19.6 7.5 34.0 19.5 9.2 6.6 13.2 34.2 21.5 12.8 5.7 11.9 55.3 34.9 24.2 8.2 6.6 16.6 15.4 23.5 5.6 17.3 21.9 170.2 18.2 13.4 15.2 10.7 TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028822-41124487 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 801.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009058, HPA019039" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No Yes 7600 "Cluster 31: Non-specific - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009058: AB_2303554, HPA019039: AB_1858187" "unprognostic (1.46e-1)" "unprognostic (8.65e-2)" "unprognostic (1.33e-2)" "unprognostic (1.92e-3)" "unprognostic (5.05e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.86e-2)" "unprognostic (1.51e-1)" "unprognostic (4.60e-2)" "unprognostic (3.74e-3)" "unprognostic (6.51e-2)" "unprognostic (8.65e-2)" "unprognostic (4.70e-2)" "unprognostic (5.14e-1)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" 37.9 36.7 17.4 49.9 18.6 74.9 27.9 21.8 25.1 26.9 25.3 36.9 42.6 27.9 34.4 36.7 22.4 37.2 19.1 18.0 18.9 39.0 47.5 40.0 59.9 18.5 18.4 24.3 28.6 26.7 22.4 50.2 18.1 31.8 37.3 25.5 26.7 24.2 21.3 26.5 42.6 23.9 18.7 38.5 36.5 18.9 18.8 58.9 37.6 20.2 60.6 42.7 28.8 19.2 105.2 71.7 131.4 108.2 52.2 61.8 129.8 92.6 81.0 105.0 94.8 190.5 127.6 296.4 96.4 48.5 112.3 98.9 159.1 147.2 153.0 64.9 81.6 378.6 54.9 139.0 135.4 165.1 124.0 69.8 76.4 102.4 166.8 94.0 111.5 98.1 167.8 98.7 120.9 233.2 235.3 119.7 106.3 104.1 131.6 197.7 123.1 157.7 121.4 95.2 108.6 75.4 145.4 88.3 95.0 94.2 98.6 146.4 109.9 84.7 71.3 78.8 100.9 62.7 75.6 338.3 113.7 91.1 82.0 12.6 9.9 16.8 6.6 10.3 8.3 10.5 7.3 7.0 9.5 10.1 7.7 6.9 19.1 6.3 13.2 18.8 9.0 5.4 17.4 18.6 21.8 25.1 18.0 18.9 18.5 18.4 18.1 18.7 18.8 19.2 116.9 118.6 201.5 66.0 117.6 245.9 338.0 90.3 153.7 98.2 90.5 75.7 49.7 78.6 170.3 99.3 60.5 192.1 137.1 194.1 74.3 94.4 10.0 151.3 167.4 115.1 91.8 486.5 86.9 65.8 175.4 121.4 84.1 259.2 78.6 119.1 67.1 131.7 99.2 72.3 77.4 126.9 69.2 101.2 109.1 12.8 59.7 151.6 72.9 74.9 95.4 88.0 78.2 87.4 90.7 119.2 169.8 69.6 234.1 162.3 94.1 136.2 68.3 87.0 85.5 135.5 130.8 116.8 54.6 129.4 214.2 801.5 111.5 123.7 117.8 237.7 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TOP3A "TOP3, ZGRF7" ENSG00000177302 "DNA topoisomerase III alpha" Q13472 17 18271428-18315007 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, Disease variant, Dwarfism, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002449 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "CAB002449: AB_564037" "unprognostic (5.49e-2)" "unprognostic (9.04e-2)" "unprognostic (8.99e-2)" "unprognostic (7.24e-3)" "unprognostic (4.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.54e-2)" "unprognostic (2.34e-1)" "unprognostic (2.74e-1)" "prognostic favorable (1.39e-4)" "prognostic unfavorable (4.59e-4)" "unprognostic (5.58e-2)" "unprognostic (8.80e-2)" "unprognostic (3.53e-2)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" 9.4 8.0 1.9 3.3 1.8 5.7 8.6 3.1 2.6 8.6 2.1 7.8 2.3 8.4 1.6 8.6 8.5 2.1 6.0 1.8 1.8 7.0 11.2 7.7 3.6 1.7 1.6 7.5 7.7 2.6 8.9 2.5 1.7 7.7 2.4 2.1 8.1 1.7 10.0 11.3 8.2 2.6 1.4 11.4 7.6 11.7 2.0 4.2 6.7 2.5 3.3 8.5 7.8 2.0 9.3 14.2 9.4 11.1 3.8 4.6 10.9 9.4 4.9 14.2 12.8 22.4 3.4 13.7 6.0 6.5 6.6 11.7 12.6 6.7 11.5 11.6 11.4 13.1 15.2 7.9 4.3 5.8 11.9 2.9 4.6 15.0 8.7 2.9 7.3 11.5 11.3 5.7 6.1 6.4 15.2 5.9 8.7 13.8 6.8 17.4 22.6 14.8 3.2 8.1 7.7 13.6 12.6 8.3 8.4 24.5 16.1 6.5 6.5 10.6 8.1 18.2 15.4 5.8 13.7 10.4 6.6 8.0 10.5 1.1 3.1 3.4 1.8 2.7 1.3 0.7 1.3 1.6 1.3 0.8 1.1 1.2 4.2 2.2 1.5 1.2 1.2 2.0 1.9 1.8 3.1 2.6 1.8 1.8 1.7 1.6 1.7 1.4 2.0 2.0 5.3 6.4 4.8 6.5 9.7 2.0 4.5 4.5 6.8 20.8 6.2 3.9 3.1 5.7 7.4 11.0 39.6 7.4 11.8 4.6 3.9 4.2 7.2 5.0 8.7 6.2 0.0 9.9 16.4 3.7 6.9 6.3 6.6 6.3 5.1 12.1 6.4 7.0 5.4 21.9 17.2 4.2 4.1 12.4 6.3 7.9 8.1 11.6 1.8 12.2 13.9 6.4 15.5 11.6 11.2 3.6 2.8 6.4 12.0 5.8 3.8 2.1 6.5 22.2 13.1 9.3 6.6 26.7 25.5 5.2 3.4 4.4 9.0 13.1 5.9 5.0 TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 32: Non-specific - Translation" Nucleoplasm "Mitochondria, Cytosol" "CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: " "unprognostic (2.29e-2)" "unprognostic (8.83e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.35e-4)" "unprognostic (9.95e-2)" "unprognostic (4.00e-2)" "unprognostic (2.79e-3)" "unprognostic (4.99e-2)" "unprognostic (2.75e-2)" "unprognostic (2.55e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (1.86e-3)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (2.74e-1)" "unprognostic (1.08e-1)" 19.3 13.8 10.4 27.1 12.6 19.6 22.5 10.4 16.5 19.9 10.3 29.0 18.9 24.5 12.8 28.8 31.3 13.2 11.1 10.1 11.4 14.9 16.5 15.1 34.6 18.7 13.6 27.3 18.3 9.4 7.3 23.5 12.5 17.7 27.5 4.1 18.9 15.3 12.3 37.4 20.4 24.6 12.6 31.1 22.6 10.4 12.3 47.2 17.4 6.1 45.4 20.8 19.9 13.3 81.5 145.3 81.1 57.3 37.3 43.9 82.8 28.4 66.1 78.5 100.2 4.2 40.6 190.5 126.9 58.7 77.6 174.9 119.7 80.4 72.8 42.7 76.5 77.6 76.8 70.9 111.5 1.6 37.0 55.7 93.0 38.9 106.5 45.6 79.4 24.7 3.8 6.9 41.5 145.1 130.0 96.3 80.2 10.4 2.4 252.2 56.1 66.2 59.4 87.3 46.0 80.5 94.1 62.6 24.3 39.4 109.2 7.4 100.7 91.6 30.2 1.0 48.3 47.6 37.9 82.5 23.6 9.7 80.1 1.2 21.2 3.4 13.0 21.7 15.9 21.5 13.3 14.6 30.3 19.1 13.7 15.4 2.4 17.5 19.3 27.3 17.3 14.7 10.4 12.6 10.4 16.5 10.1 11.4 18.7 13.6 12.5 12.6 12.3 13.3 21.1 9.6 12.8 16.3 26.0 28.7 14.5 24.6 24.5 2.6 36.1 30.4 2.5 18.6 15.4 20.2 0.0 36.9 24.7 16.9 9.8 24.8 12.8 11.5 29.0 24.5 30.7 21.7 2.1 18.1 39.6 17.0 11.2 19.5 1.3 31.7 22.1 18.0 24.2 0.0 3.2 43.0 18.3 27.8 20.1 3.8 23.0 19.3 12.4 7.5 31.9 4.9 25.7 9.0 8.0 15.8 16.4 17.0 7.8 15.7 10.3 10.1 8.8 2.6 13.1 25.9 20.6 0.5 4.9 28.7 32.8 22.4 16.5 27.4 54.1 11.5 TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004083, HPA008788, HPA022133, CAB079980" Supported Supported "Nucleoplasm,Nuclear bodies,Mitotic chromosome,Vesicles" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "Nucleoplasm, Mitotic chromosome, Vesicles" "CAB004083: AB_10694558, CAB079980: , HPA008788: AB_1078070, HPA022133: AB_1844382" "unprognostic (2.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.85e-2)" "unprognostic (4.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.03e-2)" "unprognostic (3.96e-1)" "unprognostic (2.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.34e-2)" "unprognostic (4.07e-1)" "unprognostic (8.06e-2)" "unprognostic (9.11e-2)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (3.38e-2)" 6.9 11.5 17.4 10.1 16.6 11.5 10.7 19.9 14.5 17.7 21.5 9.7 6.4 16.0 15.9 6.1 14.7 10.7 8.8 15.4 26.3 9.1 4.1 8.3 8.6 13.5 16.7 16.8 7.4 22.3 24.1 12.2 15.7 12.1 10.2 22.0 10.1 12.8 7.2 9.2 6.4 16.3 9.6 8.7 7.6 21.6 23.0 15.3 17.9 11.0 12.6 11.2 8.7 12.1 13.5 22.3 63.8 40.1 25.8 31.9 15.8 22.8 33.8 31.0 39.1 19.4 15.8 14.5 19.2 39.0 66.9 32.4 46.3 27.5 36.8 38.9 15.8 27.1 40.1 11.7 16.8 30.2 37.4 24.9 19.0 41.8 31.2 51.7 37.4 24.2 26.9 12.3 36.5 9.6 23.7 14.1 41.1 24.2 13.9 25.1 23.9 9.3 22.9 31.8 57.3 26.8 33.8 14.3 8.5 48.6 29.9 16.9 27.5 33.7 22.3 27.0 20.5 9.8 22.4 33.0 27.6 14.6 17.5 1.4 0.5 1.0 1.6 0.7 1.3 1.9 1.6 1.6 1.2 1.8 1.8 1.6 0.6 0.9 0.5 1.3 1.4 0.7 17.4 16.6 19.9 14.5 15.4 26.3 13.5 16.7 15.7 9.6 23.0 12.1 11.5 22.4 22.3 53.2 17.8 6.4 10.2 10.0 13.6 32.4 17.4 13.2 14.9 5.7 20.8 29.5 47.9 13.4 11.1 7.4 9.8 14.5 38.8 47.0 44.8 16.8 41.9 8.4 66.2 7.1 11.2 23.9 14.8 26.8 26.6 47.0 15.0 3.3 10.8 47.1 81.9 15.7 12.2 3.8 6.9 17.8 23.6 9.3 1.8 17.8 4.0 11.9 7.2 62.8 50.4 7.5 5.8 17.7 17.1 11.0 2.6 8.8 60.7 51.7 13.1 35.2 20.5 33.1 36.2 14.7 5.3 18.5 17.0 29.9 13.4 8.9 TP53BP2 "53BP2, ASPP2, PPP1R13A" ENSG00000143514 "Tumor protein p53 binding protein 2" Q13625 1 223779893-223845954 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 152.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021603, HPA050429" Supported Enhanced "Cell Junctions,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Cell Junctions, Cytosol" "HPA021603: AB_1844384, HPA050429: AB_2681124" "unprognostic (1.29e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-1)" "unprognostic (1.38e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (7.37e-2)" "unprognostic (2.67e-1)" "unprognostic (7.99e-2)" "unprognostic (5.08e-2)" "unprognostic (1.24e-1)" "unprognostic (2.81e-2)" "unprognostic (1.83e-1)" 11.7 8.5 35.3 12.2 37.2 49.8 9.5 34.7 39.4 11.4 35.6 9.9 8.5 12.6 10.0 16.8 10.1 18.4 12.2 33.0 34.4 9.7 14.9 18.4 12.8 34.9 35.8 13.8 12.0 15.8 7.1 8.9 33.2 8.9 9.9 38.0 12.4 8.1 13.0 13.0 10.0 11.1 33.5 9.3 12.4 11.2 37.4 15.8 20.7 11.2 13.1 16.6 11.7 35.8 32.8 16.2 42.9 27.3 15.0 14.5 27.3 20.6 29.3 29.4 25.1 33.6 19.2 0.0 17.5 17.3 21.3 21.9 33.9 12.3 39.3 62.9 33.2 43.1 15.2 11.5 30.3 36.0 28.9 17.5 13.3 27.2 27.7 22.1 17.7 23.6 55.7 31.7 24.8 9.5 27.5 22.2 37.0 19.7 15.6 36.0 44.7 3.7 26.5 20.4 36.9 47.6 22.8 27.9 29.9 27.9 15.8 48.6 20.7 30.0 21.1 32.7 39.2 15.4 17.3 26.4 18.1 23.9 35.0 4.8 1.2 0.8 0.9 1.3 1.2 0.9 1.1 1.8 1.3 0.8 1.1 0.8 1.4 3.3 1.0 0.8 0.8 1.0 35.3 37.2 34.7 39.4 33.0 34.4 34.9 35.8 33.2 33.5 37.4 35.8 18.2 48.1 22.7 76.4 23.7 17.2 41.6 7.2 21.1 8.1 12.6 8.0 20.3 18.6 28.3 7.3 52.1 10.3 24.2 13.0 1.9 20.4 1.1 45.0 42.2 19.1 14.9 54.3 1.7 10.7 5.9 22.6 21.9 152.0 48.8 14.1 8.6 10.7 9.8 0.0 5.3 8.7 14.2 14.1 44.4 2.4 10.5 41.7 8.8 23.4 9.6 10.0 7.2 27.2 29.0 21.4 7.3 8.6 27.4 30.9 6.7 5.5 15.6 45.5 0.0 41.2 26.3 12.3 20.1 21.1 11.6 4.8 38.8 31.4 10.2 40.6 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 187.6" "Cell type enhanced" "Detected in many" "Ionocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 50.5" "Group enriched" "Detected in many" 5 "B-cells: 50.5;NK-cells: 15.1;T-cells: 22.0" "Cell line enhanced" "Detected in many" "Karpas-707: 252.6;SK-BR-3: 572.5" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 310000 "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Golgi apparatus" "HPA028427: AB_10610561, HPA062167: AB_2684704" "prognostic unfavorable (1.11e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (3.77e-3)" "unprognostic (8.24e-2)" "unprognostic (3.75e-1)" "unprognostic (7.99e-3)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.77e-6)" "unprognostic (2.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (1.70e-2)" 5.4 9.2 34.9 28.4 40.2 8.9 75.9 34.2 69.4 19.6 36.6 117.7 98.9 9.9 56.2 34.9 15.3 31.1 11.7 42.9 35.4 46.5 30.7 19.8 44.0 33.2 37.1 2.4 41.8 27.4 34.3 22.9 36.3 104.8 129.7 187.6 80.7 18.3 8.6 46.9 100.3 10.4 32.8 16.0 84.1 5.2 53.3 15.5 64.5 9.8 56.2 20.9 20.2 48.1 131.8 34.9 1.6 23.0 0.0 0.0 51.7 8.6 12.9 34.7 17.1 18.0 37.4 189.9 45.2 0.8 25.5 52.5 52.7 36.3 24.6 23.8 44.2 26.8 46.9 29.4 0.2 8.6 0.7 0.0 25.2 0.1 12.2 21.6 2.0 128.9 0.4 252.6 0.1 43.6 42.6 39.4 11.7 148.8 86.0 0.3 0.7 122.0 60.7 31.6 64.9 44.1 40.1 572.5 110.7 51.0 55.9 34.2 2.1 0.0 35.2 0.6 30.8 94.1 87.1 155.2 22.5 0.2 2.6 0.6 0.1 5.5 12.7 0.1 22.0 50.5 12.4 11.1 2.5 44.7 8.1 9.3 0.5 15.1 0.1 5.2 9.1 8.3 34.9 40.2 34.2 69.4 42.9 35.4 33.2 37.1 36.3 32.8 53.3 48.1 17.3 44.8 67.8 10.4 133.6 80.7 89.6 83.4 51.2 171.1 105.6 54.2 22.2 82.9 78.1 66.2 118.9 98.9 28.6 230.9 170.2 112.8 20.6 25.2 8.4 26.2 169.9 11.6 85.4 79.6 116.9 6.7 97.3 72.8 1.3 15.3 25.7 40.6 13.1 32.0 53.9 331.9 476.0 14.6 24.2 13.0 1.2 10.8 104.9 37.5 91.2 50.3 60.8 69.9 181.0 79.7 317.5 1.5 270.5 214.4 132.3 135.3 21.4 232.2 0.0 49.6 8.3 1.6 18.2 91.4 124.6 231.2 51.3 0.3 247.1 135.4 TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2470.8;tongue: 2005.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA050924: AB_2681276, HPA053568: AB_2682193" "unprognostic (2.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (4.14e-3)" "unprognostic (7.49e-2)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" 340.4 588.6 446.2 269.7 480.2 334.8 274.5 476.5 541.9 314.1 446.9 425.6 421.0 240.5 220.2 764.4 248.2 216.8 819.8 481.0 462.0 609.0 536.1 308.6 253.9 459.2 460.4 269.9 238.1 496.4 236.8 287.2 467.2 272.1 435.3 625.0 377.6 273.3 2470.8 410.1 404.5 301.5 429.7 291.4 329.0 239.8 503.5 200.3 269.1 2005.8 410.4 363.8 440.6 454.4 1556.8 1350.5 706.1 1094.6 666.5 696.6 1236.3 1097.5 1184.9 1999.1 2407.5 1409.9 823.0 903.4 212.7 1069.7 1042.4 748.8 1671.0 1812.3 2189.4 1196.4 1265.1 1172.0 924.4 926.2 496.8 1351.5 924.0 764.0 739.7 1537.8 1305.0 2816.1 1233.3 451.0 615.0 336.5 1554.5 1130.0 709.6 1119.5 1741.0 1302.3 855.9 413.5 1156.1 930.7 1261.4 1061.1 497.2 830.0 953.3 977.8 542.7 1452.6 224.4 1003.2 778.2 1068.0 914.6 703.1 1631.7 653.4 285.7 1327.8 2153.1 821.2 784.9 1708.8 2304.1 2375.2 824.6 2402.3 845.7 863.3 820.0 808.0 2656.1 800.9 570.5 703.0 934.3 1387.7 2165.7 482.0 1106.3 4679.5 446.2 480.2 476.5 541.9 481.0 462.0 459.2 460.4 467.2 429.7 503.5 454.4 311.5 134.6 204.2 34.6 290.6 684.8 553.8 1756.4 414.9 284.6 294.3 303.3 552.5 391.7 673.0 389.9 110.5 1017.0 278.2 850.3 1508.5 1361.5 203.0 280.8 307.0 352.0 425.5 243.3 38.4 786.5 1824.0 386.5 408.3 343.9 362.8 364.8 276.6 547.3 937.3 297.8 33.7 567.2 1151.5 386.7 750.4 683.5 279.0 482.8 674.1 18.7 1129.8 739.6 312.0 17.1 26.7 1081.5 889.4 263.3 427.9 556.2 1595.9 1642.7 401.2 298.0 197.2 270.5 551.3 14.9 79.0 690.4 615.9 1530.4 352.9 869.2 827.0 652.5 TPM1 "C15orf13, CMH3" ENSG00000140416 "Tropomyosin 1" P09493 15 63042632-63071915 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 10621.0;skeletal muscle: 12678.0;tongue: 5183.6" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 13012.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.7" "Group enriched" "Detected in all" 4 "dendritic cells: 14.1;granulocytes: 48.7;monocytes: 19.2" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 3141.3;SuSa: 3810.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, CAB017698, HPA047089, HPA053624" Supported Approved "Actin filaments,Cytosol" NA NA 120000000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Actin filaments" Cytosol "CAB017698: AB_2272017, HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.00e-2)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (3.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (7.30e-4)" 372.0 103.6 49.8 232.9 53.2 21.6 348.8 52.4 53.9 577.4 59.3 2947.3 289.6 1566.9 250.5 639.0 823.8 288.0 10621.0 53.3 42.2 215.5 94.8 247.1 48.1 42.5 44.3 320.3 383.4 37.5 70.6 206.4 43.7 809.6 523.1 83.9 258.2 1545.5 12678.0 150.7 680.8 1754.9 44.8 134.3 976.5 52.3 50.0 21.1 156.8 5183.6 29.4 1511.0 425.8 42.2 554.5 357.3 418.1 20.9 143.1 89.9 1335.5 1509.1 552.8 905.9 669.2 253.9 107.6 1.7 677.7 1517.1 602.7 295.9 361.8 243.4 597.0 14.5 50.9 81.2 376.3 124.5 403.3 3.8 17.9 125.7 138.0 742.1 198.2 3141.3 243.2 14.7 8.7 20.4 695.3 286.4 25.6 7.1 496.0 129.0 61.1 9.0 146.5 15.8 1308.7 298.8 101.1 71.7 180.9 284.4 65.1 3810.3 204.8 15.3 1095.8 1178.8 572.0 181.6 1094.8 5.9 4.3 7.8 335.9 22.4 842.1 48.7 9.9 4.8 4.0 19.2 3.1 5.5 3.6 4.3 14.1 5.6 4.0 3.6 10.7 1.9 14.3 2.4 6.3 15.6 49.8 53.2 52.4 53.9 53.3 42.2 42.5 44.3 43.7 44.8 50.0 42.2 542.3 57.7 86.3 19.9 12.1 71.9 202.0 344.1 18.2 49.0 450.1 953.1 13012.4 346.0 147.0 318.2 383.7 212.1 20.6 561.3 187.9 2502.6 6.5 147.2 614.4 294.3 267.7 137.0 44.2 1671.1 3094.8 557.1 279.3 211.2 52.0 85.3 175.6 138.1 201.5 52.2 53.2 964.7 183.1 42.5 72.1 27.3 205.0 114.3 81.8 111.5 47.5 47.4 28.8 36.2 6.0 2372.3 623.4 1130.3 8.8 244.3 724.7 361.1 104.2 447.5 1038.7 484.0 1685.9 27.4 82.2 29.4 50.4 103.0 29.0 130.7 385.3 198.2 TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 39012.3;tongue: 16773.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1066.2;Peritubular cells: 2072.1;Sertoli cells: 2222.0;Smooth muscle cells: 2341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 812 "plasmacytoid DC: 398.6" "Lineage enriched" "Detected in single" 920 "dendritic cells: 398.6" "Cell line enhanced" "Detected in many" "BJ: 2309.6;fHDF/TERT166: 1289.0;hTERT-RPE1: 1399.1" "HPA047089, HPA053624" Approved NA NA 140000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (5.56e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (3.34e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-3)" "unprognostic (6.56e-3)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.51e-10)" "unprognostic (1.43e-2)" "unprognostic (8.33e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-2)" 331.1 285.0 88.0 411.0 89.8 16.7 260.8 92.5 117.3 651.3 127.3 3498.4 217.7 1928.1 201.9 1018.0 849.7 442.4 788.5 84.8 81.1 144.0 41.0 283.1 62.2 86.1 79.2 388.4 73.7 24.1 82.6 142.3 80.5 1219.0 238.0 8.0 393.6 1988.7 39012.3 148.5 636.2 2340.8 78.6 140.1 1252.6 82.9 83.3 26.3 138.9 16773.7 21.2 1630.1 454.9 79.8 375.4 291.2 213.9 33.6 335.4 893.3 129.3 2309.6 934.4 983.0 667.9 12.2 24.2 0.4 213.0 1289.0 144.6 9.2 3.7 291.2 457.0 716.2 10.8 9.1 1054.1 11.8 540.2 2.3 102.7 1067.7 44.9 738.8 0.4 1399.1 235.7 25.3 5.6 0.8 1052.1 15.3 2.7 29.1 269.6 1.5 17.0 18.5 391.5 3.0 31.1 7.2 3.8 13.3 470.0 7.9 18.2 273.8 6.8 27.7 30.0 16.5 585.7 11.6 730.6 0.6 2.7 2.9 34.0 6.5 29.2 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.4 0.2 0.0 398.6 0.0 2.1 88.0 89.8 92.5 117.3 84.8 81.1 86.1 79.2 80.5 78.6 83.3 79.8 110.0 3.2 4.1 10.4 5.9 57.1 81.2 274.1 24.5 0.8 29.9 1066.2 619.5 4.3 42.1 7.3 0.0 12.1 116.7 1.4 0.0 21.4 4.3 20.3 488.3 80.3 2.4 4.0 2.5 5.7 104.8 332.6 99.4 18.7 2.5 142.0 181.3 1.4 32.4 1.7 4.6 1.9 48.8 3.1 77.9 32.4 283.0 24.2 67.6 9.4 6.5 11.7 1.0 3.0 0.4 8.4 0.1 2072.1 2.9 169.8 0.4 1.3 23.5 0.9 2222.0 594.8 2341.4 2.5 27.3 6.7 42.8 14.6 16.0 106.7 2.8 28.7 TPM3 "NEM1, TRK" ENSG00000143549 "Tropomyosin 3" P06753 1 154155304-154194648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 13 "skeletal muscle: 8905.8;tongue: 6106.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 170000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Actin filaments" Cytosol "HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.64e-1)" "unprognostic (2.11e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-1)" "unprognostic (2.39e-1)" "unprognostic (2.69e-3)" "prognostic unfavorable (6.73e-6)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.80e-1)" "prognostic favorable (2.39e-5)" "prognostic unfavorable (3.65e-4)" "unprognostic (3.31e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-2)" "unprognostic (1.00e-2)" 140.7 103.2 95.0 233.2 104.1 590.1 97.1 83.3 116.2 94.9 73.3 199.0 163.5 69.6 73.4 287.4 100.6 136.1 318.5 104.8 101.5 81.5 114.4 178.7 287.3 96.6 101.4 45.4 265.9 91.7 19.6 141.1 101.6 122.3 201.5 60.3 101.5 56.0 8905.8 103.0 167.8 111.6 94.6 208.9 152.8 64.8 93.8 203.0 88.8 6106.5 287.2 183.2 29.7 98.2 529.4 332.8 306.1 225.4 262.1 341.1 317.9 439.0 419.1 597.9 437.7 596.1 513.9 414.6 366.9 500.2 206.4 472.1 320.0 468.7 485.8 315.7 171.9 537.6 234.1 311.7 200.9 728.2 627.5 260.0 246.2 515.8 355.1 224.9 929.4 269.0 411.8 429.7 710.0 342.2 582.0 683.1 714.2 775.9 515.9 510.0 233.2 574.9 405.6 387.4 234.4 409.4 360.0 443.7 419.2 303.9 645.0 788.9 758.8 558.8 353.9 497.3 711.1 332.4 623.0 516.2 490.7 514.7 860.0 932.1 743.2 1729.3 547.2 945.6 480.1 395.2 464.0 504.4 792.6 324.5 347.2 442.6 824.3 386.4 1104.4 392.9 551.5 2029.4 95.0 104.1 83.3 116.2 104.8 101.5 96.6 101.4 101.6 94.6 93.8 98.2 346.0 621.8 343.2 17.6 318.6 149.5 227.6 169.5 127.5 84.2 135.4 88.4 85.0 125.8 275.6 97.5 31.3 127.3 475.7 494.5 105.7 292.1 72.3 353.7 191.1 395.7 141.0 189.8 65.7 347.0 331.0 170.4 245.6 474.2 531.3 119.5 200.3 110.6 559.1 304.5 50.5 291.2 93.6 355.6 504.7 182.3 46.6 648.3 152.9 31.9 704.0 54.5 466.5 12.5 30.6 530.4 363.9 29.7 218.2 204.8 220.1 179.8 230.8 62.8 19.7 155.1 128.5 38.6 67.6 223.6 143.3 101.9 422.6 119.2 302.1 324.6 TPM4 ENSG00000167460 "Tropomyosin 4" P67936 19 16067021-16103002 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1297.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 2111.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004685, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 370000000 "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Actin filaments" Cytosol "CAB004685: AB_425723, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.27e-1)" "unprognostic (1.53e-2)" "unprognostic (3.62e-3)" "unprognostic (7.38e-3)" "unprognostic (3.80e-1)" "unprognostic (2.40e-2)" "unprognostic (3.11e-2)" "unprognostic (2.75e-3)" "unprognostic (1.38e-2)" "unprognostic (3.61e-1)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.26e-10)" "unprognostic (3.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" 324.1 109.9 24.7 186.3 26.3 33.8 269.0 42.1 40.4 342.4 23.4 255.0 64.6 455.0 10.6 401.8 310.0 144.8 189.6 23.2 27.0 168.1 54.1 374.1 78.2 30.7 28.7 293.8 77.9 23.6 93.4 170.7 31.9 212.1 39.2 3.6 267.2 140.4 50.3 241.4 153.8 190.4 29.1 244.1 201.4 66.2 36.6 32.4 119.4 19.3 68.5 287.5 333.8 27.8 614.5 275.2 194.7 190.9 701.3 728.2 725.6 1082.9 470.3 356.4 357.7 325.5 473.5 31.1 724.2 492.9 383.9 331.6 72.9 386.7 141.6 503.8 138.8 305.4 270.2 232.3 357.0 52.3 728.3 715.2 94.0 327.6 331.1 353.2 427.2 115.7 46.2 217.9 360.8 290.2 152.4 233.0 227.1 461.2 380.4 201.4 413.2 143.4 87.3 387.9 75.3 315.3 670.4 155.5 298.8 90.6 5.3 60.8 1237.2 954.1 166.8 2111.0 875.3 82.4 167.3 142.5 651.4 144.5 337.0 130.8 81.4 5.9 96.0 93.9 71.4 59.6 69.0 84.3 96.6 53.0 18.6 47.2 82.1 75.2 50.4 76.8 151.0 158.4 24.7 26.3 42.1 40.4 23.2 27.0 30.7 28.7 31.9 29.1 36.6 27.8 389.4 400.6 156.6 9.4 148.6 431.1 1297.2 175.2 273.8 45.9 194.3 189.4 49.1 120.1 297.0 242.8 10.4 263.5 205.6 298.4 13.7 717.1 67.3 159.0 506.6 425.5 94.0 33.4 23.8 571.6 852.9 345.1 303.7 305.0 249.6 170.8 288.8 4.2 336.8 5.0 19.0 215.8 101.7 112.0 368.8 54.8 173.1 433.2 142.3 26.2 249.5 7.5 132.8 13.6 48.5 1017.2 258.8 547.2 310.9 900.2 61.2 29.0 133.1 11.7 335.2 170.0 516.6 29.5 10.1 328.2 343.8 568.9 192.0 222.3 162.7 1025.0 TPR ENSG00000047410 "Translocated promoter region, nuclear basket protein" P12270 1 186311652-186375693 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 772.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019661, HPA019663, HPA024336" Enhanced Enhanced "Nuclear membrane" NA NA 30000000 "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear membrane" "HPA019661: AB_1858215, HPA019663: AB_1858216, HPA024336: AB_1858217" "unprognostic (4.51e-2)" "unprognostic (9.87e-3)" "unprognostic (2.48e-1)" "unprognostic (7.56e-2)" "unprognostic (9.88e-3)" "prognostic favorable (4.71e-4)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.71e-1)" "unprognostic (3.71e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-2)" "unprognostic (3.63e-2)" "unprognostic (1.31e-3)" "unprognostic (3.75e-1)" "unprognostic (4.19e-2)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" 19.8 14.5 12.2 23.4 14.1 28.9 19.7 14.4 10.9 17.6 18.4 17.6 15.5 20.3 19.7 14.8 15.0 16.1 17.1 9.5 12.9 16.0 15.4 18.0 26.0 13.6 12.0 23.1 15.5 34.2 13.4 26.7 13.8 17.2 20.0 19.8 15.8 17.6 20.4 24.2 19.3 17.6 12.2 22.9 19.1 43.8 13.3 31.0 22.7 22.3 26.0 19.6 14.5 15.1 55.9 46.7 68.2 39.8 53.4 47.4 73.2 62.0 41.2 42.8 40.4 70.5 45.9 64.0 47.1 42.1 29.4 70.9 51.9 42.4 52.1 51.8 58.6 86.8 78.3 49.7 28.7 93.1 53.5 36.4 25.0 64.4 49.4 39.3 51.3 36.5 106.0 57.3 45.8 47.5 46.2 24.5 76.1 49.9 16.0 54.3 54.3 56.5 34.8 65.0 37.7 59.5 72.9 47.1 37.6 92.5 53.1 58.0 73.0 42.5 40.6 47.7 76.6 63.2 77.6 57.0 27.5 45.8 38.7 121.4 34.1 69.0 43.8 30.0 37.7 48.9 38.6 36.8 20.6 55.4 47.3 32.8 145.7 33.0 50.4 58.7 49.1 17.3 12.2 14.1 14.4 10.9 9.5 12.9 13.6 12.0 13.8 12.2 13.3 15.1 126.4 218.0 119.6 43.1 122.9 101.2 105.5 98.6 114.9 89.8 65.8 79.8 180.0 54.3 110.0 58.8 79.2 136.9 136.8 51.2 23.5 107.1 199.3 129.1 151.7 123.8 67.7 102.4 42.5 74.7 99.9 126.5 80.5 134.4 81.0 134.2 74.6 40.8 72.8 99.3 42.6 61.9 93.6 64.2 79.3 50.4 125.6 92.6 55.2 39.4 137.3 101.1 139.0 48.2 62.8 90.1 56.7 117.4 113.7 95.1 52.4 27.7 120.9 111.4 131.5 172.5 152.1 772.9 250.4 85.6 99.2 150.8 145.8 160.0 77.7 96.0 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRAF1 EBI6 ENSG00000056558 "TNF receptor associated factor 1" Q13077 9 120902393-120929173 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Langerhans cells: 319.7;monocytes: 316.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 12.9" "Lineage enriched" "Detected in many" 4 "T-cells: 12.9" "Group enriched" "Detected in many" 6 "HDLM-2: 92.5;WM-115: 113.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001852, CAB009593" Enhanced Approved Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "CAB009593: , HPA001852: AB_1080344" "unprognostic (1.45e-3)" "unprognostic (4.51e-2)" "unprognostic (1.21e-2)" "unprognostic (3.17e-3)" "unprognostic (2.32e-2)" "unprognostic (1.48e-3)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (1.02e-2)" "unprognostic (1.39e-1)" "prognostic favorable (2.19e-5)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.42e-5)" "unprognostic (1.85e-3)" "unprognostic (5.70e-3)" "unprognostic (2.64e-1)" "unprognostic (9.87e-3)" 7.0 9.9 8.0 20.8 11.1 8.9 6.7 7.7 9.4 8.6 7.0 8.8 3.5 6.2 4.6 5.7 9.6 7.5 9.0 7.7 8.0 9.5 6.3 9.4 33.5 9.4 9.2 12.1 4.8 2.9 12.4 2.8 8.5 11.8 4.1 10.8 5.2 5.6 2.6 7.4 10.9 3.6 7.2 14.9 8.0 3.1 10.6 15.0 9.1 1.8 23.1 14.8 7.4 14.0 3.2 2.0 0.4 0.1 3.7 9.1 0.0 0.8 5.0 1.4 2.7 0.2 1.7 6.1 1.0 1.0 14.7 1.1 0.5 0.3 1.9 92.5 0.0 0.5 1.5 0.4 2.6 0.2 6.9 4.6 4.8 5.8 4.2 1.8 0.9 1.7 0.2 12.6 0.9 0.3 0.2 2.6 1.2 1.4 0.2 1.5 1.5 12.2 0.5 0.2 1.1 0.1 0.8 0.3 0.3 2.7 0.7 1.1 0.9 1.2 0.8 4.9 16.1 9.3 3.5 3.2 3.0 0.5 113.0 0.0 0.3 0.0 3.8 0.4 6.7 0.3 9.7 8.2 0.4 0.1 3.1 4.5 0.0 1.7 0.3 2.8 12.9 2.1 8.0 11.1 7.7 9.4 7.7 8.0 9.4 9.2 8.5 7.2 10.6 14.0 1.6 6.4 0.0 9.8 9.6 9.7 6.2 1.0 2.8 2.0 2.2 2.4 2.5 4.3 4.0 3.7 18.8 0.0 19.0 0.5 1.9 24.3 0.6 0.8 2.5 5.0 1.8 2.7 1.4 2.0 0.1 7.1 3.1 1.0 36.8 1.3 1.4 1.4 2.7 0.0 2.1 1.1 0.0 3.7 319.7 0.8 1.8 26.0 7.2 3.7 316.7 1.4 4.1 2.5 8.3 15.6 0.3 1.9 10.7 6.7 0.6 1.5 0.3 5.9 0.0 3.6 4.1 1.9 0.4 1.6 10.4 0.0 36.7 3.0 0.8 1.8 TRAF2 "RNF117, TRAP3" ENSG00000127191 "TNF receptor associated factor 2" Q12933 9 136881912-136926607 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004603, HPA009972, HPA010634" Uncertain Enhanced Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB004603: AB_628389, HPA009972: AB_1080350, HPA010634: AB_1080347" "unprognostic (7.77e-2)" "unprognostic (4.54e-3)" "prognostic unfavorable (9.32e-4)" "unprognostic (1.15e-1)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.91e-2)" "unprognostic (7.23e-2)" "unprognostic (4.28e-2)" "unprognostic (7.39e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.80e-3)" "unprognostic (5.52e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-2)" 8.3 7.9 14.9 13.8 16.9 16.1 9.1 20.0 18.8 10.6 13.2 11.1 9.9 8.3 4.1 15.3 8.3 6.0 11.0 15.6 14.3 10.3 15.1 9.6 20.2 17.9 15.7 7.3 8.0 4.8 10.1 8.3 18.2 12.5 5.5 4.2 11.5 8.3 8.5 12.1 12.0 6.2 14.9 16.8 9.6 17.8 15.7 17.8 14.1 5.1 14.7 11.0 11.5 18.1 25.4 76.3 20.2 18.0 5.6 8.8 39.5 20.5 11.1 29.2 19.8 47.5 44.5 31.2 25.8 12.8 39.3 65.0 27.9 33.3 11.8 47.9 22.8 23.6 76.2 30.0 8.3 23.5 23.4 6.6 9.9 23.7 13.4 10.9 13.9 28.5 40.5 34.5 13.2 36.6 38.3 33.6 33.1 57.4 33.9 35.8 31.1 42.7 18.0 19.6 32.9 15.4 25.6 58.9 23.7 22.5 42.4 27.2 15.7 37.8 24.2 24.6 34.8 14.3 25.2 31.2 13.3 19.2 28.5 2.0 4.8 9.1 12.3 5.8 17.8 15.2 13.4 15.6 6.5 12.3 10.7 13.2 4.2 14.0 12.0 14.8 24.0 8.3 14.9 16.9 20.0 18.8 15.6 14.3 17.9 15.7 18.2 14.9 15.7 18.1 7.9 0.0 6.4 7.5 12.5 11.9 14.1 18.1 4.0 6.9 8.3 7.0 7.5 12.8 8.7 5.5 0.0 19.4 7.4 23.3 3.9 19.2 3.2 4.4 4.3 11.0 11.4 9.0 5.6 12.8 28.9 6.9 9.7 6.1 10.2 11.8 4.2 4.1 13.3 18.5 4.5 16.1 6.1 2.2 8.7 4.1 3.4 6.2 14.2 2.8 32.7 4.5 11.3 2.5 5.7 20.8 6.2 7.9 11.3 20.0 15.6 6.3 5.6 9.8 19.7 4.1 7.4 17.5 23.8 5.3 12.8 17.8 13.9 6.5 15.4 10.0 TRAF3 "CAP-1, CD40bp, CRAF1, LAP1, RNF118" ENSG00000131323 "TNF receptor associated factor 3" Q13114 14 102777449-102911500 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Immunity, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002933 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA002933: AB_1080352" "unprognostic (4.06e-2)" "unprognostic (1.75e-2)" "unprognostic (2.08e-2)" "unprognostic (4.49e-3)" "unprognostic (5.25e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (1.31e-1)" "unprognostic (7.24e-2)" "unprognostic (1.16e-1)" "prognostic favorable (2.42e-5)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.71e-1)" "unprognostic (3.13e-2)" "unprognostic (2.12e-1)" 6.6 4.2 8.3 18.8 8.7 20.5 4.8 6.3 14.5 3.9 7.6 7.9 7.7 5.8 2.3 6.6 6.8 6.2 6.3 15.6 12.1 5.4 6.4 7.3 20.9 9.8 9.9 3.3 4.5 7.2 8.4 3.9 9.5 5.0 6.3 4.4 4.8 5.7 5.6 6.8 10.7 6.4 8.1 12.0 6.7 10.7 12.8 9.4 6.1 3.3 15.9 8.8 4.7 8.0 25.3 26.4 14.8 9.7 7.5 11.4 23.4 19.1 19.0 19.1 16.7 13.3 36.7 18.6 22.5 19.2 25.8 14.9 20.4 20.4 19.1 50.2 13.9 18.2 11.7 10.3 12.0 21.4 54.5 11.4 13.9 13.1 18.3 10.9 13.9 27.8 18.2 57.4 11.8 23.6 46.2 12.6 8.0 10.7 19.2 25.5 19.8 11.7 16.8 29.3 38.3 13.8 19.8 14.1 13.0 6.6 13.1 24.2 29.9 18.0 14.8 48.0 27.8 42.2 51.7 36.0 20.5 10.8 21.8 3.3 5.1 1.8 2.9 4.0 2.4 10.0 4.2 2.6 3.6 9.5 3.0 2.1 3.8 2.4 2.5 5.9 3.8 5.0 8.3 8.7 6.3 14.5 15.6 12.1 9.8 9.9 9.5 8.1 12.8 8.0 4.2 6.4 8.9 54.5 43.3 12.2 20.4 20.0 18.2 42.6 9.1 6.9 8.0 10.0 13.8 0.0 6.2 5.3 12.8 14.9 3.9 15.8 9.7 20.2 13.5 8.6 17.4 2.1 108.3 17.8 11.7 11.2 8.6 12.2 8.2 3.5 1.4 5.3 12.9 15.2 63.1 15.8 10.2 8.7 29.5 7.6 1.8 20.3 17.8 23.4 18.1 5.4 8.2 63.8 43.6 22.6 5.9 6.4 42.1 28.8 16.9 8.3 19.2 11.0 0.0 12.2 8.4 14.2 33.2 12.7 12.6 3.4 21.9 1.5 11.3 24.9 TRAF4 "CART1, MLN62, RNF83" ENSG00000076604 "TNF receptor associated factor 4" Q9BUZ4 17 28744005-28750956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Urothelial cells: 346.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 54.0" "Lineage enriched" "Detected in all" 6 "dendritic cells: 54.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009055, HPA021904, HPA052377" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB009055: AB_2209701, HPA021904: , HPA052377: AB_2681804" "unprognostic (1.77e-1)" "unprognostic (9.05e-2)" "unprognostic (1.31e-2)" "unprognostic (2.51e-3)" "unprognostic (1.76e-1)" "unprognostic (7.38e-3)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (7.13e-2)" "unprognostic (7.55e-2)" "unprognostic (1.74e-3)" "unprognostic (6.98e-2)" "unprognostic (9.26e-2)" "unprognostic (2.77e-2)" "unprognostic (5.58e-3)" 10.7 19.4 16.1 11.2 17.8 31.2 19.3 15.6 19.1 10.9 18.4 28.4 47.1 9.1 4.1 28.6 14.4 20.3 5.2 15.5 15.5 45.0 60.1 22.7 18.8 18.6 17.7 12.2 32.1 4.0 14.5 16.4 17.0 31.4 22.2 3.6 46.8 6.9 1.8 15.4 38.7 5.1 15.6 19.0 35.9 15.1 16.3 13.6 29.1 0.8 20.1 36.7 11.8 23.9 41.2 62.7 85.3 41.6 12.0 13.9 131.2 27.3 22.8 28.2 37.2 50.2 50.0 62.5 38.8 29.9 19.0 61.0 39.1 61.5 11.6 20.3 58.5 22.5 111.7 58.3 45.9 10.9 25.0 26.5 59.2 33.2 39.7 25.5 22.2 29.1 60.1 5.4 26.1 67.3 34.6 22.7 65.9 80.2 14.4 52.1 38.8 30.6 80.8 115.7 53.2 61.3 42.0 181.7 84.3 73.4 69.5 17.2 15.0 17.8 37.4 20.3 39.2 8.2 21.3 80.1 14.0 17.8 81.9 5.7 0.5 1.9 1.0 1.1 2.6 9.7 1.8 1.9 2.9 9.3 1.3 1.3 0.2 1.8 0.9 54.0 1.0 1.8 16.1 17.8 15.6 19.1 15.5 15.5 18.6 17.7 17.0 15.6 16.3 23.9 9.3 22.4 28.3 28.4 59.2 137.5 185.0 58.2 122.3 3.4 134.8 100.1 0.4 44.3 66.7 20.2 6.2 107.9 88.3 121.3 43.0 78.5 53.4 102.8 22.8 20.7 84.1 4.8 0.9 109.2 136.8 20.4 83.1 133.7 7.0 10.1 8.9 38.1 13.9 8.4 1.6 81.6 61.1 2.2 71.9 12.1 3.7 16.0 39.2 3.7 7.3 23.0 5.2 37.7 19.8 128.0 125.7 1.5 36.6 219.0 155.7 33.8 68.7 2.3 0.0 9.8 34.9 5.8 22.6 57.7 78.6 124.4 31.5 14.5 93.5 346.4 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 29.1 29.4 16.5 24.4 15.1 35.0 28.2 18.2 23.0 32.1 17.0 38.0 40.0 31.2 11.6 54.6 30.4 22.2 21.3 17.9 14.6 28.1 51.5 33.2 22.9 17.8 15.3 23.5 37.4 14.6 32.1 20.6 14.8 27.0 17.4 8.5 34.7 16.5 30.4 47.7 35.2 18.8 14.2 34.5 35.6 14.8 17.7 19.1 25.6 9.9 18.6 34.5 34.8 14.3 57.7 72.2 40.3 72.5 40.8 76.5 47.4 43.4 53.9 49.9 44.6 88.2 72.1 36.6 50.2 55.4 31.8 65.9 38.1 76.8 18.8 58.3 48.8 52.4 98.5 68.3 53.8 56.3 72.7 76.2 62.8 48.1 62.6 41.0 97.4 70.6 57.1 47.9 48.2 131.1 58.3 65.2 79.7 78.7 34.8 107.4 66.7 74.2 40.2 30.4 80.9 67.2 36.3 68.5 48.6 20.9 78.1 68.2 74.3 60.2 83.9 56.7 48.2 69.2 55.0 48.4 34.4 35.9 47.8 4.0 9.1 7.3 4.5 12.4 4.3 5.5 4.4 4.7 11.2 3.9 3.1 3.8 6.2 2.9 8.9 5.3 6.5 5.3 16.5 15.1 18.2 23.0 17.9 14.6 17.8 15.3 14.8 14.2 17.7 14.3 18.9 0.0 9.2 12.4 18.2 28.8 21.1 34.2 22.8 15.9 31.6 27.9 4.9 21.5 20.8 14.7 6.2 23.5 17.4 56.4 17.6 39.0 5.0 23.6 34.6 26.5 34.0 33.6 8.9 59.0 36.3 19.0 38.7 27.9 9.5 22.1 26.0 32.3 42.2 37.0 8.2 38.7 34.6 41.8 21.3 13.1 24.8 26.8 10.6 8.4 33.9 12.6 6.2 6.6 4.9 53.0 43.6 22.2 24.0 33.8 80.0 29.2 19.7 10.9 6.6 11.9 18.3 8.5 25.3 50.7 32.5 26.7 16.0 29.0 42.5 38.5 TRIM23 "ARD1, ARFD1, RNF46" ENSG00000113595 "Tripartite motif containing 23" P36406 5 65589690-65625975 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039605 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "HPA039605: AB_10673146" "unprognostic (4.06e-1)" "unprognostic (1.07e-1)" "unprognostic (5.11e-2)" "unprognostic (3.63e-1)" "unprognostic (7.96e-2)" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" "unprognostic (5.00e-3)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (3.19e-1)" "unprognostic (3.19e-2)" "unprognostic (1.06e-2)" "unprognostic (2.62e-1)" "unprognostic (6.55e-3)" "unprognostic (2.70e-1)" 8.1 10.8 12.3 6.0 13.8 7.7 8.2 18.1 17.7 9.1 5.2 6.1 3.9 9.2 6.0 7.4 7.0 5.3 11.0 14.5 12.0 8.8 10.8 5.7 7.5 10.8 10.2 13.2 5.4 8.4 4.7 7.1 12.9 11.4 4.3 14.6 5.5 7.6 13.2 6.2 4.6 7.8 12.7 7.6 4.4 10.4 12.0 8.6 10.6 17.5 6.7 6.3 5.2 19.3 8.5 11.8 12.6 18.2 17.9 17.9 9.1 16.7 15.2 13.3 16.4 12.2 8.2 6.7 18.8 11.0 13.8 7.3 11.7 9.4 20.1 6.7 15.0 5.8 15.7 6.6 16.8 3.8 7.2 14.0 8.1 14.9 13.5 12.7 6.4 8.0 6.4 9.2 16.5 7.8 7.4 4.0 6.6 1.5 4.7 6.6 21.9 9.7 7.3 8.6 7.5 10.2 15.9 4.4 13.2 10.3 10.3 4.6 11.0 10.5 11.4 13.2 12.3 11.3 12.2 8.8 12.1 6.6 10.4 19.9 3.5 8.9 4.7 2.8 5.9 3.9 5.1 4.0 3.2 4.7 8.0 6.1 9.2 5.1 4.4 3.5 6.4 3.9 12.3 13.8 18.1 17.7 14.5 12.0 10.8 10.2 12.9 12.7 12.0 19.3 13.8 19.2 7.8 28.1 13.1 6.9 2.3 4.4 7.4 28.2 7.0 7.1 22.3 10.0 6.8 5.5 16.7 3.8 12.5 4.7 5.9 4.9 7.0 9.4 21.3 11.1 6.6 21.0 49.1 3.1 2.6 17.1 5.6 7.6 3.8 19.7 13.9 13.0 3.9 45.4 49.3 4.4 2.0 10.0 3.5 4.2 20.8 7.4 10.6 24.4 6.8 27.2 8.2 39.7 49.7 5.8 4.3 17.0 11.4 9.1 6.0 10.1 11.8 24.8 32.9 16.0 12.9 27.2 16.9 5.0 6.3 7.0 13.1 16.0 3.8 6.9 TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460259-138589996 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "AF22: 146.5;HMC-1: 196.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043495: AB_10962915, HPA061717: AB_2684592" "unprognostic (2.40e-1)" "unprognostic (9.52e-3)" "unprognostic (2.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.94e-4)" "prognostic favorable (6.57e-4)" "unprognostic (4.01e-2)" "unprognostic (8.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (5.54e-2)" "unprognostic (6.34e-2)" 7.5 25.7 6.0 6.9 6.8 10.6 9.1 5.8 7.0 6.4 5.2 8.1 10.0 8.8 8.4 9.0 5.7 5.3 10.4 6.0 7.1 8.0 23.1 11.4 8.0 6.8 6.4 30.0 10.8 14.2 3.8 12.3 6.3 11.7 9.2 12.2 8.3 5.2 13.9 8.6 9.7 7.6 6.2 7.2 11.6 27.3 8.2 17.3 9.1 16.4 7.8 7.5 6.1 9.0 15.0 18.1 146.5 42.7 9.6 8.9 11.4 13.7 14.4 10.5 10.2 28.7 13.6 28.7 13.2 13.2 21.5 7.9 71.9 11.4 15.4 22.1 17.7 63.1 13.1 88.9 13.1 49.8 196.8 7.9 11.8 8.8 13.9 7.3 25.0 15.4 72.6 17.1 12.7 29.2 85.2 44.8 56.3 77.6 16.0 66.5 17.3 24.2 23.6 43.9 30.3 68.8 25.5 22.6 7.5 50.6 15.5 32.3 10.7 12.1 9.9 21.4 19.1 15.6 18.2 47.8 20.1 32.1 18.0 0.3 0.6 1.0 0.5 0.6 0.1 0.2 0.4 0.3 0.5 0.3 0.4 0.5 0.9 0.6 0.3 0.3 0.7 0.2 6.0 6.8 5.8 7.0 6.0 7.1 6.8 6.4 6.3 6.2 8.2 9.0 29.0 51.3 46.9 26.1 9.5 13.9 13.4 13.8 10.8 13.6 14.7 14.4 39.7 20.0 18.8 7.3 16.7 28.4 14.9 12.2 5.9 7.1 70.4 16.7 22.9 18.9 10.1 31.3 27.9 12.4 15.2 16.0 20.4 25.2 40.4 85.2 14.3 31.9 10.3 40.4 46.6 10.9 14.2 9.5 14.9 38.7 14.0 13.8 14.2 21.5 12.2 23.3 9.2 64.3 67.1 9.5 9.5 16.1 13.7 12.2 6.8 10.6 14.5 22.4 13.1 21.5 17.6 72.8 14.7 22.2 11.8 22.2 15.8 34.6 19.4 12.8 TRIM25 "EFP, RNF147, ZNF147" ENSG00000121060 "Tripartite motif containing 25" Q14258 17 56836387-56914080 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Ligase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 23.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 23.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005909 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA005909: AB_1078722" "unprognostic (8.73e-3)" "unprognostic (1.57e-2)" "unprognostic (2.06e-2)" "unprognostic (6.06e-2)" "unprognostic (2.69e-1)" "unprognostic (3.78e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (1.53e-1)" "unprognostic (4.23e-1)" "unprognostic (1.15e-1)" "prognostic favorable (3.36e-4)" "unprognostic (3.23e-1)" "unprognostic (3.11e-2)" "prognostic favorable (9.35e-4)" "unprognostic (5.21e-2)" "unprognostic (5.13e-2)" "unprognostic (7.39e-2)" 16.3 20.7 9.8 19.8 10.4 47.7 13.1 9.5 23.2 14.5 11.1 19.7 19.4 12.1 8.5 20.4 18.2 9.7 11.1 9.0 11.3 11.9 29.8 25.0 17.3 10.3 9.9 14.3 16.7 13.0 10.3 9.5 10.3 9.3 17.3 11.8 15.3 7.4 12.6 29.2 20.2 12.4 11.4 41.6 17.0 9.1 12.1 18.5 10.8 7.6 19.7 12.1 14.6 9.0 77.2 37.4 9.0 30.7 66.6 55.8 0.1 29.6 59.6 69.4 59.3 36.7 41.1 74.6 59.8 28.6 75.4 44.5 44.5 39.9 38.5 64.1 35.0 48.1 29.0 41.0 57.0 58.2 33.2 25.1 65.7 36.2 76.4 32.9 46.7 50.2 12.0 43.8 35.8 51.3 65.6 41.9 5.8 63.3 71.5 46.3 30.2 47.4 40.5 59.7 17.5 16.3 23.3 37.1 69.7 5.8 50.3 46.8 31.3 32.2 23.1 50.1 31.2 24.7 51.1 12.1 31.2 39.4 13.0 4.8 3.0 1.2 1.0 2.5 1.3 2.2 0.9 1.0 3.1 1.7 0.7 1.0 23.5 1.1 1.8 2.2 2.0 1.1 9.8 10.4 9.5 23.2 9.0 11.3 10.3 9.9 10.3 11.4 12.1 9.0 27.3 35.3 19.8 7.5 12.7 18.5 8.5 10.5 13.1 9.9 12.6 11.9 7.5 20.0 16.6 9.2 29.2 5.4 15.1 54.8 0.0 19.1 3.5 44.9 20.0 32.7 18.6 11.1 4.1 21.6 10.7 16.0 32.6 72.5 3.8 23.0 32.2 30.9 14.8 3.3 8.2 28.7 6.1 27.5 24.6 2.1 9.6 29.3 14.2 8.4 28.3 5.7 11.3 12.1 0.3 32.2 54.2 9.4 17.7 21.6 20.0 8.0 18.5 22.2 6.6 13.1 9.2 0.4 0.3 24.5 30.5 15.9 11.5 45.3 25.7 25.4 TRIM27 "RFP, RNF76" ENSG00000204713 "Tripartite motif containing 27" P14373 6 28903002-28923988 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 49.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048684, HPA053408" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA048684: AB_2680493, HPA053408: AB_2682139" "unprognostic (1.57e-1)" "unprognostic (1.48e-2)" "unprognostic (2.36e-1)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (2.56e-1)" "unprognostic (2.00e-3)" "unprognostic (1.17e-2)" "unprognostic (1.01e-2)" "unprognostic (1.12e-3)" "unprognostic (4.76e-3)" "unprognostic (1.16e-2)" "prognostic unfavorable (3.50e-6)" "unprognostic (1.27e-1)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "prognostic favorable (2.71e-4)" 23.8 28.1 1.8 7.2 1.7 1.1 23.3 1.1 2.6 33.0 2.2 23.0 8.7 24.5 0.0 20.5 31.0 0.5 24.3 1.6 1.3 32.7 59.5 26.8 2.2 2.2 2.1 30.8 53.0 0.6 33.8 4.5 1.8 35.1 0.6 0.1 25.8 6.5 21.2 17.6 26.8 2.3 1.5 45.8 27.3 14.4 2.0 0.9 26.3 0.0 1.0 28.7 22.6 2.0 2.4 8.2 1.2 21.7 2.8 6.2 0.3 16.1 0.8 5.1 6.2 6.1 1.7 1.6 1.1 4.8 1.3 17.5 4.0 9.2 0.5 1.3 2.6 20.3 2.5 9.3 4.3 2.0 5.7 0.1 1.0 4.1 1.3 0.6 4.5 5.8 2.1 12.1 1.3 4.9 11.1 0.9 0.0 3.4 13.5 20.1 4.6 49.7 3.9 2.3 4.9 18.7 19.9 11.6 4.1 0.6 11.6 12.2 13.1 6.3 9.3 14.7 5.1 31.7 2.7 17.9 6.8 24.8 20.0 5.2 4.4 2.5 7.0 12.5 11.3 7.0 10.6 5.5 8.5 1.8 4.1 7.6 2.7 6.4 7.0 5.6 5.2 9.9 1.8 1.7 1.1 2.6 1.6 1.3 2.2 2.1 1.8 1.5 2.0 2.0 21.4 16.0 24.8 11.8 32.2 28.4 41.9 27.4 33.6 11.7 32.2 24.6 18.3 24.3 24.0 29.5 16.7 46.4 25.4 15.9 21.5 39.5 12.9 27.1 27.0 32.0 27.6 24.6 13.5 43.4 55.5 25.5 26.5 27.2 21.5 36.9 27.8 42.1 41.1 8.4 13.4 38.5 26.4 28.3 23.5 6.8 23.9 29.0 8.8 16.9 46.5 10.4 29.9 19.1 19.7 48.9 18.7 18.4 51.2 53.3 19.3 27.6 23.9 13.6 19.7 14.8 31.0 8.0 16.1 25.8 19.6 45.6 28.9 43.7 28.3 30.9 TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392790-114511203 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 115.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoplasm "HPA004345: AB_1858287" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "prognostic favorable (6.20e-4)" "unprognostic (1.09e-2)" "unprognostic (8.42e-3)" "prognostic favorable (8.93e-4)" "unprognostic (1.34e-2)" "unprognostic (1.83e-1)" "unprognostic (6.75e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-2)" "unprognostic (4.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" 9.3 8.1 10.1 10.7 11.3 25.4 13.5 18.3 16.9 12.5 8.2 9.5 8.8 15.2 29.8 11.7 9.1 10.9 8.9 11.5 9.9 13.5 12.2 10.9 13.3 8.0 9.1 14.4 12.2 15.3 7.3 16.0 8.2 12.6 10.1 18.8 10.7 11.0 8.8 14.8 8.9 11.8 8.1 12.7 11.2 25.3 9.5 17.8 14.2 10.7 12.8 11.5 9.8 11.3 30.9 16.3 30.1 22.6 12.5 13.1 51.0 15.4 16.3 20.9 22.1 18.5 12.8 32.8 15.5 18.1 13.6 17.4 27.6 18.0 28.6 24.9 16.4 31.6 21.7 21.6 13.8 40.3 25.3 12.5 12.9 24.9 25.2 16.0 17.8 27.3 40.1 22.5 20.2 115.4 40.9 17.0 40.7 11.7 16.3 34.8 45.9 10.8 14.9 47.7 20.8 21.9 29.2 34.7 27.4 19.3 15.8 21.7 20.1 14.5 23.4 33.8 21.7 15.7 15.6 33.4 20.4 23.0 42.0 13.2 1.2 6.1 2.5 1.5 2.2 3.0 2.6 2.7 1.5 1.4 2.0 3.1 3.6 4.1 2.4 3.0 1.6 0.8 10.1 11.3 18.3 16.9 11.5 9.9 8.0 9.1 8.2 8.1 9.5 11.3 31.0 19.2 33.3 70.5 35.4 52.8 28.9 28.6 25.6 75.6 35.9 23.9 29.2 30.0 32.3 55.2 98.0 64.9 53.9 33.3 1.9 21.0 237.3 50.4 37.5 33.2 52.1 37.9 120.7 23.6 34.0 28.7 30.1 90.0 37.4 55.6 40.7 44.3 29.6 26.9 108.5 30.4 30.5 50.3 47.9 97.9 49.0 37.2 19.6 79.6 42.9 31.5 54.6 116.6 101.8 31.4 34.9 36.9 31.6 47.3 26.6 17.3 31.4 58.3 32.9 38.3 32.5 60.0 31.9 31.2 55.4 87.7 42.8 48.1 31.2 55.3 TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 193.3;tongue: 51.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 17.8;Cardiomyocytes: 40.1;Squamous epithelial cells: 39.6;Suprabasal keratinocytes: 28.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 16.4;HDLM-2: 35.0;PC-3: 18.8;TIME: 16.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" 2.1 1.5 1.2 0.4 1.0 0.4 2.1 10.5 3.0 5.5 0.4 1.9 0.3 1.3 3.1 27.0 2.2 0.2 8.5 0.9 1.7 3.9 0.6 2.6 0.4 3.1 2.9 1.5 4.8 2.7 5.5 0.3 2.8 2.8 0.5 1.6 7.3 0.6 193.3 28.7 1.3 0.6 1.3 1.4 2.2 1.3 2.0 0.4 6.3 51.0 2.1 2.2 9.5 1.3 9.0 4.4 0.1 0.5 0.7 0.8 0.2 1.9 0.0 0.7 1.8 0.4 12.0 0.6 6.1 2.6 3.7 16.4 4.8 13.8 0.2 35.0 1.8 0.9 12.2 0.2 2.2 0.0 2.0 0.1 10.5 0.4 6.7 2.7 3.9 1.6 0.5 2.0 0.4 1.3 0.5 0.3 0.0 14.5 18.8 0.4 6.0 1.4 4.9 0.0 0.4 1.1 4.2 0.2 6.5 0.2 1.0 0.4 16.0 0.2 3.4 0.6 6.3 2.8 0.4 1.0 0.5 0.7 1.5 0.0 1.7 0.0 0.4 0.7 0.7 0.1 0.4 0.4 0.3 0.2 0.7 0.5 0.0 0.1 0.5 0.2 0.9 0.3 1.2 1.0 10.5 3.0 0.9 1.7 3.1 2.9 2.8 1.3 2.0 1.3 7.3 0.0 1.1 0.0 1.0 17.8 4.3 11.1 12.0 6.2 0.8 1.5 40.1 0.0 6.3 3.7 0.0 0.1 0.8 5.9 5.9 0.7 0.9 0.2 0.3 4.6 0.0 0.0 1.3 2.4 0.7 4.8 11.2 0.7 0.0 0.1 5.7 0.4 1.1 0.0 3.9 3.3 2.0 6.0 2.8 0.0 0.9 2.9 1.8 0.0 5.7 0.6 1.0 2.0 0.1 5.0 6.5 1.5 0.1 2.5 0.0 1.5 2.9 2.9 13.1 17.3 5.8 1.5 0.4 39.6 28.4 0.0 1.4 0.1 3.4 5.3 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143342-14532128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 205.7;Excitatory neurons: 400.9;Inhibitory neurons: 443.4;Microglial cells: 308.2;Oligodendrocyte precursor cells: 476.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 215.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: AB_2685315" "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 35.3 20.5 31.7 11.6 33.3 5.5 31.8 32.2 38.6 23.4 34.5 36.6 6.8 38.9 15.5 14.5 21.2 18.8 31.9 37.2 33.6 24.9 22.1 25.7 10.2 28.1 28.1 52.8 20.6 9.1 28.9 11.6 26.6 28.2 13.6 10.2 17.4 11.1 20.9 18.7 27.8 19.2 26.4 38.9 22.9 17.2 31.4 13.3 17.0 17.4 10.6 27.1 20.5 27.2 43.7 15.9 37.2 18.0 78.6 101.0 41.3 40.4 49.2 32.6 36.9 10.3 17.4 10.4 28.0 56.6 79.6 13.0 6.5 19.4 66.6 25.8 8.0 5.5 46.1 13.2 40.0 13.9 14.8 47.6 19.9 114.4 36.4 30.3 28.8 6.8 1.4 6.8 78.7 8.3 0.1 9.5 9.3 4.8 13.7 9.9 22.9 34.2 31.6 20.5 17.1 67.5 34.3 9.0 18.9 47.1 5.3 2.0 66.4 61.4 38.3 44.7 48.4 0.3 2.2 12.9 215.1 8.8 14.8 0.1 0.5 0.0 0.0 0.7 0.1 0.7 0.0 0.0 0.5 1.8 0.0 0.0 0.0 1.6 0.6 1.1 0.3 0.1 31.7 33.3 32.2 38.6 37.2 33.6 28.1 28.1 26.6 26.4 31.4 27.2 33.0 19.2 25.9 205.7 16.6 16.4 13.0 15.6 17.1 30.5 21.9 15.0 19.3 10.0 21.0 11.0 14.6 9.7 5.6 24.8 0.0 21.2 2.9 11.7 24.8 28.7 18.0 6.5 400.9 14.2 22.0 38.9 7.7 34.2 17.7 17.2 14.6 17.1 14.2 28.6 443.4 20.6 14.2 15.4 22.1 6.6 78.6 20.2 5.4 308.2 12.1 7.3 2.1 476.5 80.4 38.5 14.9 42.9 29.2 52.8 9.2 5.4 18.3 2.7 6.6 27.5 20.0 3.5 6.2 7.2 13.8 8.2 3.8 11.7 19.4 20.3 TRIP11 "CEV14, GMAP-210, GMAP210, Trip230" ENSG00000100815 "Thyroid hormone receptor interactor 11" Q15643 14 91965991-92040896 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002570, HPA070684" Supported Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoplasm "HPA002570: AB_1078995, HPA070684: AB_2686295" "unprognostic (1.65e-1)" "unprognostic (2.81e-2)" "unprognostic (7.14e-2)" "unprognostic (1.12e-1)" "unprognostic (6.89e-2)" "unprognostic (1.39e-1)" "unprognostic (3.49e-3)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (7.33e-3)" "unprognostic (2.04e-1)" "unprognostic (1.21e-1)" "prognostic favorable (1.78e-6)" "unprognostic (1.78e-1)" "unprognostic (5.08e-1)" "unprognostic (7.74e-2)" "unprognostic (5.55e-2)" 10.4 10.5 4.7 8.6 8.8 7.6 10.5 10.8 7.4 11.6 13.5 10.1 10.4 9.7 6.7 12.1 7.7 10.1 10.6 3.5 5.4 13.5 12.9 8.0 9.4 6.2 7.3 11.0 25.5 19.2 4.8 11.6 6.8 9.6 9.8 10.6 11.0 8.5 11.8 8.9 7.9 10.2 6.2 8.6 15.3 13.6 6.5 11.2 16.7 15.6 11.4 10.4 5.8 10.7 22.8 22.5 14.4 15.2 24.8 38.1 21.8 35.3 27.0 17.1 19.5 13.8 36.0 15.8 25.3 31.3 13.3 29.1 19.1 17.1 37.0 24.1 5.8 17.9 20.4 13.1 18.9 21.2 17.1 14.7 20.4 30.3 25.8 18.9 27.8 8.7 11.9 17.8 27.0 31.7 12.2 5.2 6.6 22.1 16.0 14.8 27.5 8.0 15.3 36.5 10.5 9.5 28.5 16.6 11.0 14.5 36.2 10.5 36.9 19.8 13.8 20.8 16.1 15.7 25.9 14.2 23.2 11.7 25.3 9.3 9.7 20.2 13.9 9.0 13.6 13.0 14.7 13.1 7.9 23.7 14.2 14.9 9.6 14.8 16.1 14.3 14.5 4.3 4.7 8.8 10.8 7.4 3.5 5.4 6.2 7.3 6.8 6.2 6.5 10.7 66.8 54.5 79.8 57.5 32.5 16.6 30.7 31.7 21.6 61.1 39.9 40.0 115.7 34.3 54.0 38.6 73.0 44.2 41.4 29.8 17.6 72.5 13.6 58.2 81.2 53.9 32.2 30.7 58.1 46.2 32.0 51.7 39.8 56.5 37.9 68.7 32.9 37.5 24.4 43.7 74.7 40.4 32.6 25.7 11.2 14.7 62.1 30.4 7.2 51.5 41.6 56.5 47.4 66.9 92.4 44.7 29.5 54.2 26.3 39.0 31.6 23.4 56.4 70.4 59.2 76.6 50.4 105.0 65.8 19.5 17.0 72.5 30.2 79.8 32.9 35.1 TRIP4 "ASC-1, HsT17391, ZC2HC5" ENSG00000103671 "Thyroid hormone receptor interactor 4" Q15650 15 64387748-64455303 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Congenital muscular dystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016605, HPA050666" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nuclear bodies" "HPA016605: AB_1858339, HPA050666: AB_2681211" "unprognostic (1.56e-1)" "unprognostic (1.14e-1)" "unprognostic (2.62e-1)" "unprognostic (4.50e-2)" "unprognostic (5.79e-2)" "unprognostic (1.08e-1)" "unprognostic (7.16e-2)" "unprognostic (3.01e-2)" "unprognostic (4.98e-2)" "unprognostic (2.83e-1)" "unprognostic (1.25e-1)" "unprognostic (2.37e-2)" "prognostic favorable (6.34e-6)" "unprognostic (2.41e-1)" "unprognostic (2.96e-1)" "unprognostic (2.61e-2)" "unprognostic (1.25e-1)" 14.9 12.4 13.6 13.3 14.7 15.3 17.1 14.1 20.6 13.0 14.9 17.1 17.1 13.2 11.6 19.4 14.1 11.0 15.5 13.7 14.0 27.5 14.3 15.0 16.4 14.4 14.2 13.1 16.6 20.0 13.0 16.9 14.8 12.7 19.2 16.8 13.3 12.1 8.9 18.0 17.9 16.5 14.2 16.6 15.6 12.0 14.5 19.8 25.6 9.2 18.7 17.7 14.7 15.6 18.6 27.1 23.3 16.7 18.9 24.6 21.8 19.3 24.7 32.7 31.5 22.8 40.5 13.3 6.3 29.4 26.6 25.7 38.3 22.0 30.9 27.0 10.9 19.4 19.2 24.1 33.5 21.2 35.1 30.9 28.2 25.9 27.0 18.7 28.9 19.2 22.7 16.2 30.4 21.2 13.5 21.3 13.7 32.7 14.4 20.4 17.7 22.2 31.6 35.1 12.6 19.8 17.3 20.7 35.3 43.5 26.2 31.3 25.7 23.2 15.8 15.6 27.7 13.5 25.9 13.5 19.2 21.4 29.6 70.1 22.2 54.3 20.8 29.1 17.7 16.0 19.7 21.2 20.5 16.3 16.6 17.3 30.9 21.2 42.4 16.2 23.3 16.9 13.6 14.7 14.1 20.6 13.7 14.0 14.4 14.2 14.8 14.2 14.5 15.6 12.7 22.4 13.2 15.3 10.0 8.4 9.6 23.3 2.2 11.1 7.6 7.1 10.3 7.2 18.1 12.9 12.5 22.2 20.1 15.3 13.7 25.2 20.4 21.7 10.7 13.2 11.4 9.9 32.5 27.1 26.8 10.2 10.2 16.2 19.6 12.3 10.0 4.4 21.7 15.2 25.8 8.2 24.4 12.9 7.6 3.7 11.8 15.3 14.2 22.5 27.5 10.0 27.8 18.1 30.9 33.6 10.5 12.8 6.5 6.0 13.5 44.6 26.7 17.3 6.6 9.0 15.0 19.3 21.4 5.4 6.3 24.2 14.4 12.1 8.1 7.8 TRO "KIAA1114, MAGE-D3, MAGED3" ENSG00000067445 Trophinin Q12816 X 54920462-54931431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.1" "Cell type enhanced" "Detected in many" "Astrocytes: 9.4;Excitatory neurons: 14.6;Granulosa cells: 12.3;Inhibitory neurons: 20.0;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 9.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 37.1;SH-SY5Y: 33.8;SuSa: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071449 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "Plasma membrane, Cytosol" "HPA071449: " "unprognostic (6.18e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.09e-3)" "unprognostic (2.72e-1)" "unprognostic (5.66e-2)" "unprognostic (1.46e-1)" "unprognostic (4.67e-2)" "unprognostic (3.18e-1)" "prognostic favorable (1.93e-4)" "unprognostic (1.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.67e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (6.86e-2)" 3.9 3.0 13.9 1.3 10.6 1.0 3.7 0.8 23.7 9.5 0.9 3.2 0.9 13.4 6.6 1.6 5.3 4.2 2.4 9.3 17.2 3.9 16.8 2.1 1.6 6.2 5.1 17.5 7.1 5.3 24.4 4.3 6.9 5.5 2.1 6.2 1.5 5.2 31.1 1.2 1.6 8.6 3.4 1.0 2.0 2.6 12.6 4.7 10.1 1.0 1.6 2.5 5.5 13.3 0.0 0.3 37.1 0.1 7.1 9.8 0.0 2.1 13.1 2.0 0.7 0.0 0.0 0.0 5.3 13.8 3.1 0.2 0.3 0.6 1.0 0.1 23.3 18.0 0.0 1.5 2.7 0.0 0.1 22.8 0.0 12.0 0.0 11.8 0.9 9.1 0.0 0.2 14.0 0.0 0.3 0.1 19.6 0.1 0.0 11.3 16.4 0.1 3.5 0.3 25.3 33.8 0.0 0.5 3.1 74.2 0.0 2.2 0.0 15.7 15.9 0.2 2.2 5.8 0.9 0.0 2.3 0.0 13.8 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.2 0.1 0.9 0.0 0.1 13.9 10.6 0.8 23.7 9.3 17.2 6.2 5.1 6.9 3.4 12.6 13.3 0.4 0.0 0.0 9.4 0.3 0.4 1.4 0.8 5.2 4.2 0.5 1.9 1.8 0.0 1.9 3.7 0.0 0.8 0.2 0.0 0.0 1.7 0.4 0.3 7.9 1.9 0.0 0.0 14.6 0.2 0.6 7.0 0.5 0.5 1.3 12.3 0.4 0.0 0.5 8.4 20.0 0.0 0.0 0.0 0.4 0.6 5.9 0.2 0.0 1.0 0.1 2.2 0.0 17.1 9.4 0.2 0.0 3.8 0.1 0.4 0.0 0.4 0.0 0.9 0.0 1.5 3.3 1.2 1.9 0.1 0.1 0.7 0.7 2.9 0.0 0.3 TRRAP "PAF400, TR-AP, Tra1" ENSG00000196367 "Transformation/transcription domain associated protein" Q9Y4A5 7 98877933-99050831 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Autism spectrum disorder, Cancer-related genes, Deafness, Disease variant, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054376 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Golgi apparatus" "HPA054376: AB_2682467" "unprognostic (2.10e-1)" "unprognostic (7.79e-2)" "unprognostic (2.21e-1)" "unprognostic (4.35e-2)" "unprognostic (2.02e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.40e-2)" "unprognostic (2.39e-2)" "unprognostic (3.99e-2)" "unprognostic (9.45e-2)" "unprognostic (7.02e-2)" "unprognostic (2.21e-3)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" 6.0 8.1 3.4 7.4 3.5 11.1 6.2 10.3 3.7 8.3 5.9 7.7 5.3 8.6 3.5 6.8 8.4 4.9 6.8 3.1 2.6 6.2 6.7 7.0 9.3 1.4 2.2 10.9 8.3 10.3 14.0 6.1 1.9 7.1 5.0 7.5 7.1 5.2 7.6 11.2 8.4 6.2 0.6 8.5 7.1 11.0 2.8 15.8 8.8 7.3 8.7 7.3 7.0 5.0 24.0 27.2 27.7 23.4 12.9 13.8 13.7 10.3 13.6 15.8 15.1 21.2 10.3 32.8 15.9 19.1 30.3 12.2 29.1 14.0 17.7 19.2 28.3 20.2 20.3 11.7 9.4 36.9 14.3 12.6 8.0 25.8 21.7 10.9 20.5 29.2 35.4 59.8 14.8 44.0 45.0 13.5 21.1 14.1 16.6 32.7 16.0 25.2 7.7 26.6 21.6 27.1 26.1 16.6 8.4 22.7 8.5 15.7 22.0 21.1 30.6 28.3 24.2 24.7 30.2 47.8 14.9 18.3 21.3 2.8 0.3 0.2 0.5 0.2 0.9 0.6 0.8 0.4 0.3 0.8 0.6 0.6 1.0 0.5 0.3 1.0 0.7 0.1 3.4 3.5 10.3 3.7 3.1 2.6 1.4 2.2 1.9 0.6 2.8 5.0 12.8 16.0 14.2 30.3 16.4 15.8 4.2 8.2 13.1 15.2 13.7 10.0 10.9 5.7 9.4 14.7 27.1 8.9 15.0 7.9 0.0 7.7 3.6 16.6 20.1 11.1 12.6 12.4 43.7 6.5 5.2 11.1 11.2 24.1 5.7 26.5 8.6 11.0 8.0 21.9 45.5 10.4 8.2 10.4 7.4 5.4 8.7 12.3 8.8 29.0 9.8 6.1 6.2 36.7 42.4 8.3 5.8 8.6 25.3 7.6 6.2 5.2 8.3 9.2 0.0 12.8 12.4 14.8 8.4 18.5 21.3 10.9 17.1 12.1 10.1 7.5 TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011568, CAB012481, HPA074132" Supported Enhanced Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB011568: AB_732752, CAB012481: , HPA074132: AB_2686666" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (6.67e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (1.96e-2)" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.01e-4)" "unprognostic (1.84e-2)" "prognostic favorable (7.91e-4)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.35e-1)" "unprognostic (1.16e-1)" 11.8 14.5 6.1 5.2 6.0 9.0 12.2 8.3 6.8 13.7 3.6 13.4 5.1 12.0 6.5 10.1 11.8 5.4 14.0 6.0 5.1 13.1 10.9 11.4 6.3 4.5 5.2 18.2 12.8 7.4 16.2 9.3 4.9 13.1 7.1 8.3 11.4 5.4 14.9 15.8 12.6 7.9 1.1 14.9 12.2 22.8 4.5 6.7 17.3 14.6 8.6 11.4 12.7 4.4 8.3 9.7 13.0 10.7 13.0 12.2 24.2 10.3 17.6 11.5 11.0 16.5 9.5 19.4 4.7 20.9 17.0 21.0 15.4 11.0 11.3 9.4 8.2 6.1 19.9 13.6 15.6 9.4 8.0 13.6 8.2 14.3 17.4 11.1 13.0 16.9 11.1 10.2 12.9 15.4 8.3 7.8 17.8 12.1 7.8 9.9 24.5 11.0 5.0 10.7 6.4 10.0 12.7 7.9 6.2 15.2 14.4 5.5 13.8 18.1 10.8 11.4 7.7 5.7 13.8 18.5 10.3 5.2 8.2 2.1 2.3 2.8 3.2 3.8 3.5 0.9 1.7 2.9 1.7 1.2 2.9 2.6 0.9 3.0 1.8 0.9 3.1 1.5 6.1 6.0 8.3 6.8 6.0 5.1 4.5 5.2 4.9 1.1 4.5 4.4 14.7 22.4 27.2 35.3 10.8 7.5 6.2 5.1 9.6 26.6 11.2 9.5 29.2 7.2 10.3 11.0 37.5 15.1 13.5 7.1 13.7 11.7 45.9 18.0 22.2 12.7 16.8 15.8 53.6 7.2 24.0 14.0 14.3 25.8 8.8 27.4 9.7 5.9 9.2 25.2 59.0 10.0 10.2 7.7 7.9 133.1 15.5 12.8 12.4 19.7 10.8 9.7 7.2 30.7 47.8 12.5 7.9 11.3 12.4 9.0 8.9 7.3 16.2 24.4 19.7 19.5 15.4 22.4 20.0 11.8 8.7 21.1 11.9 23.2 10.6 11.0 TSC2 "LAM, PPP1R160, TSC4, tuberin" ENSG00000103197 "TSC complex subunit 2" P49815 16 2047967-2089491 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "GTPase activation" "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002225, HPA030409, HPA049679" Approved Enhanced Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Cytosol "CAB002225: AB_564043, HPA030409: AB_10602483, HPA049679: AB_2680848" "unprognostic (2.80e-1)" "unprognostic (1.01e-1)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (1.02e-1)" "unprognostic (1.03e-3)" "unprognostic (2.04e-2)" "unprognostic (6.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.94e-2)" "prognostic favorable (5.06e-4)" "unprognostic (4.32e-2)" "unprognostic (3.91e-2)" "unprognostic (2.14e-2)" "unprognostic (2.54e-1)" "unprognostic (1.51e-2)" "unprognostic (8.96e-2)" 12.6 10.0 3.8 10.2 4.6 10.9 12.6 4.5 6.1 16.7 0.9 15.3 12.4 17.4 7.3 12.0 16.0 10.9 12.6 5.9 1.3 9.6 9.0 12.0 7.7 3.1 1.5 18.4 14.8 14.7 16.5 9.2 2.7 12.4 9.1 17.7 21.3 15.6 31.1 14.4 12.8 11.4 0.1 11.4 15.7 16.2 2.6 11.7 18.6 14.5 7.8 14.0 12.8 12.5 13.5 21.4 28.9 32.5 33.7 28.1 24.3 31.7 21.7 23.4 19.7 25.7 25.4 20.5 27.6 26.2 11.0 22.0 17.5 23.1 17.3 15.5 28.5 19.2 39.6 10.7 23.0 24.0 22.4 33.5 14.3 18.9 13.9 27.9 22.3 14.4 19.0 17.7 21.0 27.0 28.9 7.1 29.8 10.1 21.2 45.3 31.6 25.7 9.4 12.1 22.1 41.3 45.2 29.4 15.3 28.2 26.8 17.5 35.5 24.5 16.5 22.0 16.5 39.0 42.7 40.8 10.2 9.7 29.6 3.2 2.7 2.8 3.1 2.1 2.8 1.8 1.9 1.7 2.5 1.8 1.3 2.1 3.5 1.6 1.7 0.6 1.4 2.2 3.8 4.6 4.5 6.1 5.9 1.3 3.1 1.5 2.7 0.1 2.6 12.5 23.8 25.6 18.9 43.8 16.8 9.2 8.1 10.1 14.8 53.8 23.7 20.2 41.8 21.5 15.3 20.2 93.8 13.0 17.3 34.5 3.9 15.2 13.1 47.8 26.3 25.6 32.5 17.4 22.8 14.1 8.0 19.7 44.9 62.1 8.8 49.0 32.2 38.7 11.4 45.4 22.4 26.6 8.2 17.6 9.9 29.3 28.3 13.8 8.8 15.9 12.1 19.0 36.0 18.6 25.7 21.4 17.5 25.9 14.4 9.4 25.4 8.9 17.8 64.7 13.1 17.2 20.4 18.3 37.7 12.9 9.8 9.3 18.8 31.6 28.9 10.6 TSG101 "TSG10, VPS23" ENSG00000074319 "Tumor susceptibility 101" Q99816 11 18468336-18526951 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004283, HPA006161" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoli, Plasma membrane" "CAB004283: AB_671392, HPA006161: AB_1080408" "unprognostic (1.42e-1)" "unprognostic (7.91e-2)" "unprognostic (2.11e-1)" "unprognostic (6.77e-2)" "unprognostic (1.82e-1)" "unprognostic (2.72e-3)" "prognostic unfavorable (3.74e-6)" "unprognostic (5.67e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-2)" "unprognostic (4.15e-3)" "unprognostic (4.27e-2)" "prognostic favorable (5.52e-6)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" 40.4 55.6 41.1 32.2 42.2 60.8 56.6 43.1 50.8 44.8 45.7 49.5 42.8 40.2 56.3 56.7 49.3 36.5 68.2 42.1 44.5 70.1 62.3 43.9 42.9 42.4 42.3 44.6 45.4 61.5 36.5 61.4 42.4 43.1 59.0 43.6 46.4 41.1 77.1 47.2 43.4 42.9 43.9 34.0 45.4 55.5 41.8 45.9 52.4 83.0 57.4 46.9 42.2 46.5 51.3 79.1 73.7 51.1 82.2 85.4 63.7 77.1 103.0 92.2 90.3 54.3 27.5 65.5 49.2 86.4 103.7 77.0 74.0 70.3 102.0 95.4 87.7 41.1 38.6 79.7 106.3 64.6 69.8 75.0 139.9 48.6 131.6 102.2 76.8 68.4 66.9 55.2 112.7 85.7 45.7 66.8 45.1 115.6 81.5 37.0 72.5 54.7 63.6 68.8 52.2 88.6 75.7 61.6 101.1 77.1 59.7 64.8 43.1 63.0 38.0 126.4 59.4 37.2 76.0 56.9 64.5 34.2 80.5 187.8 69.8 155.7 50.4 81.6 52.4 78.5 48.0 54.0 66.1 69.2 51.5 54.9 123.6 57.9 114.3 54.5 84.4 91.1 41.1 42.2 43.1 50.8 42.1 44.5 42.4 42.3 42.4 43.9 41.8 46.5 63.0 64.1 57.5 22.9 44.4 42.6 81.5 159.2 26.7 41.0 39.2 42.2 68.0 42.9 90.4 44.1 25.0 191.9 34.2 85.5 125.2 112.4 48.0 58.4 36.0 54.4 61.6 74.5 29.1 101.3 107.7 48.6 32.6 48.9 44.9 46.2 47.2 36.0 79.6 37.0 28.4 65.0 156.6 45.2 33.6 21.2 56.2 51.6 56.9 26.2 82.3 86.1 54.6 32.2 32.8 132.7 76.2 43.2 47.0 103.0 72.2 126.8 113.4 43.3 46.0 44.7 81.2 177.6 153.7 32.8 48.4 296.1 38.1 91.5 47.8 97.4 TSHR LGR3 ENSG00000165409 "Thyroid stimulating hormone receptor" P16473 14 80954989-81146306 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "thyroid gland: 273.9" "Group enriched" "Detected in some" 4 "Astrocytes: 5.5;Excitatory neurons: 7.0;Inhibitory neurons: 12.3;Microglial cells: 6.5;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 9.5;Plasma cells: 11.7;Skeletal myocytes: 4.1" "Cancer enriched" "Detected in some" 116 "thyroid cancer: 100.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "naive B-cell: 1.7;T-reg: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 1.7;T-cells: 6.9" "Cell line enhanced" "Detected in some" "JURKAT: 58.4;MOLT-4: 23.8;SCLC-21H: 23.0;U-266/70: 11.3" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.3" CAB000473 Approved "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000473: AB_2303782" "unprognostic (3.36e-3)" "unprognostic (1.31e-3)" "unprognostic (1.02e-2)" "unprognostic (4.17e-6)" "unprognostic (3.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (3.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" "unprognostic (7.11e-3)" "unprognostic (5.08e-7)" "unprognostic (1.32e-1)" "unprognostic (7.40e-2)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" 0.5 0.6 1.6 0.8 1.8 1.2 0.8 4.0 2.3 0.2 0.2 0.5 0.3 0.6 0.5 0.2 0.8 0.5 0.3 1.3 0.5 0.3 0.4 0.2 1.9 0.8 0.3 0.3 0.4 0.3 0.2 0.4 0.5 0.5 0.3 2.3 0.6 0.2 0.8 1.1 0.4 0.2 0.1 0.8 0.5 0.7 1.2 20.8 273.9 0.2 0.8 0.3 0.1 1.8 0.4 0.2 0.7 0.4 0.1 0.1 0.3 0.2 0.0 0.0 0.1 0.4 0.5 0.7 0.2 0.1 0.5 0.3 0.3 0.0 0.1 0.3 0.1 0.3 0.8 0.4 0.0 0.2 0.4 0.3 0.1 0.1 0.3 0.1 0.0 58.4 0.3 0.7 0.1 0.4 23.8 0.5 0.4 0.1 0.2 0.8 0.2 0.9 0.0 0.5 23.0 0.4 0.2 0.2 0.3 0.5 0.3 0.1 0.2 0.7 0.5 0.6 0.3 11.3 6.3 0.6 0.3 0.3 0.5 0.5 0.1 0.1 0.1 0.1 0.1 0.6 0.5 0.3 0.1 1.7 0.2 0.1 0.9 0.1 0.2 0.5 6.9 0.1 1.6 1.8 4.0 2.3 1.3 0.5 0.8 0.3 0.5 0.1 1.2 1.8 0.2 0.0 0.5 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.8 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.1 0.2 0.3 1.8 0.0 7.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 6.5 0.0 0.1 0.0 6.6 9.5 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.6 0.0 4.1 1.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TSPAN8 "CO-029, TM4SF3" ENSG00000127324 "Tetraspanin 8" P19075 12 71125085-71441898 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 951.1;stomach 1: 631.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1688.5;Ductal cells: 943.3;Intestinal goblet cells: 886.7;Paneth cells: 2225.8;Proximal enterocytes: 3546.1;Undifferentiated cells: 1583.9" "Group enriched" "Detected in many" 4 "colorectal cancer: 283.9;pancreatic cancer: 156.9;stomach cancer: 194.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "OE19: 2160.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA022273, CAB026009, HPA044337" Enhanced Approved Vesicles NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB026009: , HPA022273: , HPA044337: AB_2678899" "unprognostic (1.64e-1)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.40e-2)" "unprognostic (6.81e-2)" "unprognostic (7.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-3)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.66e-5)" "unprognostic (1.88e-2)" "unprognostic (1.00e-1)" "unprognostic (2.97e-2)" "prognostic favorable (7.36e-5)" 11.1 9.7 1.9 126.9 5.2 0.0 17.0 6.1 7.1 28.6 1.6 951.1 916.0 12.5 11.7 5.5 13.4 208.2 5.5 1.8 3.4 57.6 53.2 23.0 4.6 12.4 4.9 41.8 60.0 0.4 2.5 2.0 10.5 163.9 862.0 0.3 76.4 10.8 63.7 13.6 848.3 39.2 8.5 0.3 631.0 5.8 4.4 1.1 6.5 12.4 3.8 11.0 4.0 14.6 0.0 0.7 0.0 0.0 5.2 0.8 2.8 0.0 0.0 0.0 0.0 48.8 3.1 0.0 0.2 0.0 0.6 6.5 0.0 0.0 0.0 0.2 0.1 0.0 52.2 3.3 0.0 0.0 0.2 0.4 0.3 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.3 0.0 0.2 3.0 0.3 2160.7 173.3 0.2 0.0 4.9 34.1 41.0 4.1 7.7 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.3 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.2 6.1 7.1 1.8 3.4 12.4 4.9 10.5 8.5 4.4 14.6 0.8 0.0 2.2 0.0 6.1 20.8 32.5 14.0 0.6 0.3 8.5 1.8 0.3 346.0 76.7 44.1 0.0 1.2 0.0 1688.5 127.2 943.3 34.5 3.7 4.5 3.8 174.1 0.0 0.1 654.9 0.6 37.3 645.3 44.8 4.5 0.0 2.2 26.0 0.2 0.0 0.1 886.7 16.2 2.2 29.1 17.9 44.1 2.6 64.0 0.0 7.8 10.3 0.0 0.5 14.3 325.0 2225.8 32.0 2.2 376.2 3546.1 2.5 30.2 0.6 0.0 7.7 23.6 0.5 1.0 2.7 13.5 1.1 5.8 10.7 1583.9 46.0 TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS" ENSG00000100300 "Translocator protein" "B1AH88, P30536" 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 690.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1429.2;Pancreatic endocrine cells: 1442.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 516.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (5.29e-3)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (4.02e-3)" "unprognostic (3.95e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.34e-3)" 249.3 164.5 42.3 65.3 46.3 488.7 204.3 50.9 61.1 217.3 45.8 189.7 73.6 91.8 8.7 690.1 108.5 39.4 174.7 39.9 51.0 120.5 81.9 181.5 44.3 61.9 48.8 72.3 93.4 22.4 50.8 30.5 57.4 126.6 33.9 4.2 244.9 28.9 84.0 388.0 116.9 26.6 58.0 206.9 216.9 21.4 59.5 22.2 77.4 27.5 39.9 135.7 355.5 69.0 300.0 143.3 10.2 134.4 54.7 175.3 10.8 216.6 107.0 109.4 115.7 28.8 222.4 0.3 147.8 175.7 52.2 242.2 27.9 171.7 13.9 49.5 111.4 28.9 150.4 10.1 193.4 66.4 145.0 137.5 276.4 65.9 58.2 125.8 262.9 0.2 24.0 53.6 114.2 244.5 1.1 188.5 11.6 154.0 355.7 67.0 0.0 516.2 139.3 173.8 14.0 65.4 103.9 200.4 263.5 0.1 76.3 256.6 269.7 132.6 96.9 135.5 92.9 21.7 4.1 2.7 170.0 218.3 171.4 656.8 1678.5 931.0 314.7 1051.6 247.7 199.2 429.9 309.2 1170.2 266.9 325.9 264.3 1052.3 365.0 713.1 209.0 539.5 1585.6 42.3 46.3 50.9 61.1 39.9 51.0 61.9 48.8 57.4 58.0 59.5 69.0 225.5 160.3 140.0 3.6 88.9 366.8 392.3 1429.2 554.3 2.8 269.3 360.2 92.1 323.1 555.7 206.0 2.1 10.0 140.3 680.7 369.8 578.5 2.4 170.8 143.6 220.4 194.9 239.9 0.3 586.4 284.9 205.1 440.9 309.5 268.6 124.3 187.1 110.5 758.5 3.3 0.8 636.8 478.1 644.7 524.7 11.7 82.6 611.6 723.9 10.3 776.9 180.5 207.0 6.0 20.1 1442.1 705.9 157.6 76.3 526.2 471.9 180.7 283.2 19.4 105.2 108.2 197.8 2.8 4.5 1067.4 536.0 20.0 180.0 30.5 664.1 786.1 TTLL9 "C20orf125, dJ310O13.1" ENSG00000131044 "Tubulin tyrosine ligase like 9" Q3SXZ7 20 31870702-31944963 "Cancer-related genes, Predicted intracellular proteins" Ligase "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.4;choroid plexus: 10.3;epididymis: 2.6;fallopian tube: 6.2;testis: 5.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 20.8;Early spermatids: 39.3;Endometrial ciliated cells: 25.8;Late spermatids: 69.8;Oligodendrocytes: 28.0;Respiratory ciliated cells: 50.2" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041772, HPA055676" Uncertain Uncertain Nucleoplasm,Microtubules NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Microtubules" "HPA041772: AB_10959904, HPA055676: AB_2682881" "unprognostic (8.77e-2)" "unprognostic (8.19e-3)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (4.63e-1)" "unprognostic (1.53e-3)" "unprognostic (1.80e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.59e-1)" "unprognostic (9.05e-3)" "unprognostic (6.17e-2)" "unprognostic (8.35e-3)" "unprognostic (1.84e-1)" "unprognostic (1.70e-1)" "unprognostic (1.25e-3)" "unprognostic (2.23e-2)" 0.1 0.1 2.0 0.0 2.1 0.0 0.2 2.2 2.2 0.9 10.3 0.0 0.0 0.1 2.6 0.0 6.2 0.1 0.0 2.5 2.3 0.7 0.0 1.1 0.1 3.8 4.4 0.1 0.2 0.6 0.9 0.0 3.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 3.0 0.2 0.0 5.0 2.4 0.0 0.6 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.1 2.2 2.2 2.5 2.3 3.8 4.4 3.0 3.0 2.4 2.6 0.2 12.8 20.8 13.1 0.1 0.1 1.1 1.1 0.0 1.8 0.4 0.6 0.9 0.0 8.1 0.0 4.2 0.1 0.1 0.0 0.0 0.2 39.3 25.8 0.7 1.1 0.0 0.0 5.6 0.0 0.0 1.6 0.0 0.8 7.6 0.8 0.4 0.1 0.0 5.0 7.8 0.2 2.0 0.6 0.5 69.8 1.5 3.5 0.0 1.0 0.8 0.4 0.0 15.1 28.0 0.1 0.0 1.2 0.0 0.5 0.0 0.2 50.2 0.8 0.0 0.8 0.7 13.8 1.2 0.0 0.1 0.0 2.7 0.4 0.0 0.4 TTR "CTS, CTS1, HsT2651, PALB" ENSG00000118271 Transthyretin P02766 18 31557009-31598833 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Transport "Hormone, Thyroid hormone" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "choroid plexus: 142023.1" "Cell type enriched" "Detected in many" 30 "Hepatocytes: 23659.3" "Group enriched" "Detected in many" 28 "liver cancer: 928.2;pancreatic cancer: 666.0" "Group enriched" "Detected in all" 7 "cerebellum: 621.7;hippocampal formation: 1730.9;thalamus: 688.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 160.1;EFO-21: 39.6;Hep G2: 249.0;U-2 OS: 57.0" "Group enriched" "Detected in all" 5 "basal ganglia: 1538.3;hippocampal formation: 4891.0;pons and medulla: 5758.5;thalamus: 3400.4" "Region enhanced" "Detected in all" "medulla oblongata: 1381.8" "CAB002517, HPA002550, CAB062567, CAB073406" Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 345000000000 99000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB002517: AB_563965, CAB062567: AB_2665620, CAB073406: , HPA002550: AB_1080419" "unprognostic (6.79e-3)" "unprognostic (3.38e-2)" "unprognostic (4.10e-1)" "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (8.15e-2)" "unprognostic (3.74e-2)" "unprognostic (9.66e-3)" "unprognostic (8.72e-2)" "unprognostic (1.23e-2)" "unprognostic (8.35e-3)" "unprognostic (5.26e-1)" "unprognostic (3.52e-2)" 4.2 0.6 148.5 0.5 56.7 9.6 0.4 621.7 83.7 2.0 142023.1 6.0 14.9 1.3 0.9 2.2 0.8 51.2 2.9 1730.9 37.3 18.4 21288.1 0.8 2.4 106.5 86.0 1.1 1785.1 186.8 6.0 2.7 27.1 1.6 4.5 80.1 1.8 0.4 1.1 15.6 6.8 0.3 12.3 3.8 49.8 2.3 688.2 1.1 1.3 0.0 0.1 2.3 0.6 133.9 1.6 0.4 0.6 0.5 0.8 0.1 1.0 0.8 0.3 0.0 0.0 160.1 0.0 2.9 39.6 0.5 0.6 0.4 0.0 0.3 0.0 5.9 0.8 5.2 1.8 249.0 0.4 11.2 1.0 0.1 0.1 0.1 0.0 0.7 0.0 0.3 2.8 0.4 0.0 0.5 0.4 0.7 0.6 4.5 0.3 0.3 7.4 0.2 0.3 1.6 0.9 1.1 5.8 0.0 0.2 1.7 0.6 0.2 1.7 2.4 57.0 0.5 4.3 1.0 2.6 17.6 0.7 4.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.1 0.0 0.1 0.0 0.0 148.5 56.7 621.7 83.7 1730.9 37.3 106.5 86.0 27.1 12.3 688.2 133.9 0.0 0.0 0.0 0.0 15.1 0.5 0.0 0.0 0.0 144.8 0.0 0.0 1.8 779.2 0.0 5.5 162.6 0.3 0.0 1.5 5.9 3.1 6.8 0.5 0.5 14.1 356.2 192.5 0.0 2.0 3.6 0.7 13.3 0.0 0.0 0.2 192.4 23659.3 2.4 26.9 0.1 19.6 0.0 313.7 0.0 8.7 0.3 1.2 0.0 0.0 0.0 24.9 0.0 0.0 0.0 130.5 5.2 0.0 0.0 0.2 1.3 26.9 0.0 56.0 0.0 0.0 0.3 3.3 1.1 0.0 0.1 4.0 10.9 0.0 1.7 0.0 TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1313.3" "Cell type enhanced" "Detected in all" "Ductal cells: 1162.0;Respiratory ciliated cells: 1173.3;Smooth muscle cells: 1005.3" "Cancer enriched" "Detected in all" 9 "glioma: 942.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1660.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 3100.7;SCLC-21H: 1983.9" "Low region specificity" "Detected in all" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Microtubules "CAB008686: AB_1624202, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (3.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.77e-1)" "unprognostic (1.14e-1)" "unprognostic (4.73e-1)" "unprognostic (1.15e-2)" "unprognostic (2.56e-2)" "unprognostic (2.12e-1)" "unprognostic (3.49e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (9.79e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.07e-2)" "unprognostic (4.27e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-3)" 150.3 133.5 803.3 166.9 990.4 152.0 179.7 1083.4 882.6 185.8 692.7 466.4 54.4 406.3 166.6 140.0 342.0 193.1 156.5 784.4 1066.9 64.9 21.1 214.3 71.7 1209.8 1002.4 172.8 53.5 79.1 163.4 123.9 1136.6 173.4 126.5 259.7 104.7 267.3 37.4 107.9 125.9 865.4 1083.5 84.7 135.6 69.0 987.8 162.7 39.7 94.1 55.9 210.1 117.1 1313.3 3.2 154.4 3100.7 419.3 263.1 613.9 10.5 286.4 325.6 163.2 390.4 9.4 54.8 120.7 322.4 824.7 304.0 6.4 388.0 97.3 120.3 97.0 138.1 41.5 27.6 34.4 54.1 70.2 3.2 359.5 33.8 325.0 31.8 627.1 945.9 237.2 45.0 124.5 888.7 70.3 276.5 59.2 335.0 3.6 112.5 225.4 232.3 14.1 718.9 13.8 1983.9 1150.3 79.1 4.5 106.0 449.9 210.4 97.3 929.1 178.6 108.5 21.2 80.5 41.5 126.9 234.2 93.8 117.2 191.6 503.5 260.5 824.7 159.0 554.9 118.1 158.2 140.0 146.7 314.0 166.9 134.2 125.2 1660.9 89.9 812.8 101.1 172.8 495.5 803.3 990.4 1083.4 882.6 784.4 1066.9 1209.8 1002.4 1136.6 1083.5 987.8 1313.3 296.9 230.8 181.5 49.9 220.8 87.2 250.6 179.3 59.7 233.0 140.0 291.6 187.9 25.8 148.1 64.4 77.2 10.5 202.9 4.5 25.4 1162.0 10.0 414.9 413.6 334.2 785.8 48.0 78.2 16.2 12.8 391.5 63.2 102.4 547.9 695.0 165.6 2.8 452.0 249.0 60.6 15.5 329.6 80.7 277.6 20.7 193.6 204.2 183.2 37.5 616.6 788.9 77.2 73.4 432.6 333.3 12.8 142.6 32.5 60.4 1.5 73.3 1173.3 349.6 164.3 542.7 1005.3 15.4 31.2 20.9 99.3 15.9 266.5 40.6 12.4 95.7 TUSC2 "C3orf11, FUS1, PAP, PDAP2" ENSG00000114383 "Tumor suppressor 2, mitochondrial calcium regulator" O75896 3 50320027-50328251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030116 Approved Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Vesicles "HPA030116: AB_10602253" "unprognostic (1.58e-2)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (8.46e-2)" "unprognostic (2.73e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.53e-3)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.47e-2)" "unprognostic (1.99e-2)" "prognostic favorable (8.70e-7)" "unprognostic (9.22e-3)" "unprognostic (1.98e-1)" "unprognostic (3.15e-1)" "unprognostic (6.34e-3)" 17.7 25.4 53.4 14.9 54.1 12.4 17.0 51.0 56.2 16.3 43.9 25.2 12.8 17.7 28.2 18.9 20.6 11.5 35.4 54.8 55.5 29.2 25.9 18.4 17.1 54.6 56.2 15.8 27.4 34.8 21.5 17.3 55.6 22.1 16.6 36.0 18.4 17.8 50.9 13.8 20.3 13.7 50.5 23.7 26.9 22.6 56.1 20.4 23.1 36.4 20.5 20.5 14.2 50.8 24.7 20.2 27.5 30.1 29.8 15.4 30.1 19.3 26.5 36.3 30.7 35.6 22.0 41.8 21.0 18.3 37.4 15.5 33.9 25.7 31.7 24.8 31.2 20.6 18.6 38.7 26.1 36.7 34.8 16.8 40.7 36.5 18.1 25.5 38.0 32.8 25.4 19.6 21.1 18.8 38.7 46.5 37.6 30.4 28.9 13.3 13.4 34.4 36.9 26.4 14.7 30.3 14.4 25.4 29.9 27.2 24.2 44.3 30.3 10.8 26.6 24.8 40.2 47.6 79.7 29.4 24.2 24.1 17.4 16.7 21.2 34.6 24.0 19.6 24.3 23.0 20.8 25.2 14.2 24.6 23.5 25.2 30.2 22.4 18.1 26.3 25.2 32.3 53.4 54.1 51.0 56.2 54.8 55.5 54.6 56.2 55.6 50.5 56.1 50.8 39.8 12.8 17.0 3.9 41.7 57.5 36.8 60.7 37.0 55.5 61.0 44.2 39.6 55.8 37.9 57.0 22.9 62.9 54.4 46.5 115.4 73.9 123.1 55.6 15.8 39.2 50.4 40.4 12.9 74.1 55.5 24.9 25.0 28.4 29.9 16.4 40.4 72.7 76.6 74.0 11.4 46.1 73.2 46.1 51.1 351.8 27.1 37.7 55.2 5.6 57.6 69.0 59.8 4.0 7.8 74.0 61.0 24.8 45.8 67.8 72.0 178.6 71.5 45.5 13.1 18.0 38.5 54.1 49.2 47.4 91.2 69.6 38.7 28.9 46.1 63.7 TWIST1 "ACS3, bHLHa38, BPES2, BPES3, CRS, CRS1, H-twist, SCS, TWIST" ENSG00000122691 "Twist family bHLH transcription factor 1" Q15672 7 19020991-19117636 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 25.2" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 92.8;Fibroblasts: 73.4;Langerhans cells: 30.3;Smooth muscle cells: 34.4;Theca cells: 29.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "SH-SY5Y: 263.5" "Low region specificity" "Detected in single" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.58e-2)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (3.62e-1)" "unprognostic (1.29e-2)" "unprognostic (9.80e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-2)" "unprognostic (8.51e-3)" "unprognostic (5.91e-2)" "unprognostic (8.99e-3)" "unprognostic (3.69e-1)" "unprognostic (1.29e-9)" "unprognostic (8.55e-3)" "unprognostic (1.54e-1)" "unprognostic (6.83e-3)" "unprognostic (1.97e-2)" 22.1 4.9 2.2 1.3 1.8 0.0 25.2 1.5 2.6 6.4 2.7 2.7 0.0 18.9 0.6 5.9 3.0 7.2 4.5 1.9 1.6 0.8 0.2 0.6 2.4 1.8 2.3 6.4 0.4 0.2 7.1 12.6 2.0 2.7 0.4 0.0 8.1 0.8 1.5 16.0 0.7 5.0 1.8 0.0 5.4 2.7 2.0 0.5 3.7 1.9 1.6 8.3 5.0 2.2 1.6 2.0 8.9 0.0 45.0 18.4 0.2 38.3 17.8 28.9 37.7 0.0 0.0 0.0 4.0 32.0 6.9 0.0 3.7 3.0 19.0 8.5 10.1 0.0 3.9 0.0 26.8 10.0 0.1 44.8 9.9 6.0 15.7 8.6 0.0 0.5 0.0 0.0 31.0 0.0 0.0 0.5 3.9 0.0 15.7 0.0 0.0 0.0 0.0 0.0 15.9 263.5 6.2 0.0 8.2 5.6 0.8 12.4 0.2 35.5 0.1 28.3 6.6 0.0 0.0 0.0 19.4 0.0 45.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.8 1.5 2.6 1.9 1.6 1.8 2.3 2.0 1.8 2.0 2.2 10.3 0.0 0.0 0.7 0.1 12.5 0.2 2.9 1.8 0.0 0.5 3.3 0.9 0.0 0.5 0.0 0.0 0.3 0.1 0.1 1.9 0.0 0.2 11.5 92.8 3.8 0.0 0.0 5.2 0.0 0.2 73.4 0.0 13.3 0.0 2.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 30.3 0.8 2.1 0.9 12.4 7.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.3 0.3 0.0 1.6 34.4 0.5 4.7 0.6 8.5 1.4 2.2 29.9 0.1 0.4 TXLNA DKFZp451J0118 ENSG00000084652 "Taxilin alpha" P40222 1 32179675-32198285 "Cancer-related genes, Predicted intracellular proteins" Exocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045383, HPA072477" Supported Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Nucleoplasm, Centrosome" "HPA045383: AB_10967649, HPA072477: AB_2686525" "prognostic favorable (6.24e-4)" "unprognostic (1.19e-2)" "unprognostic (3.01e-1)" "unprognostic (1.99e-1)" "unprognostic (5.04e-2)" "prognostic favorable (5.53e-4)" "prognostic unfavorable (1.57e-6)" "unprognostic (3.67e-3)" "unprognostic (2.75e-1)" "unprognostic (5.25e-3)" "prognostic favorable (8.69e-5)" "unprognostic (5.06e-2)" "prognostic unfavorable (7.21e-7)" "unprognostic (3.94e-3)" "unprognostic (3.28e-1)" "unprognostic (7.24e-2)" "unprognostic (1.03e-1)" 26.1 35.8 20.6 20.7 22.0 16.5 20.3 20.6 21.3 30.7 27.5 32.2 16.9 35.4 22.7 30.7 30.5 18.7 22.2 20.4 22.8 30.0 45.6 23.1 22.0 25.3 23.6 29.0 29.2 32.5 31.7 16.7 22.1 30.1 17.9 12.6 23.2 21.7 21.8 31.3 24.4 27.8 21.5 28.5 26.5 29.4 23.9 19.3 27.0 14.5 27.0 28.6 24.3 22.7 45.1 37.7 38.5 43.5 48.8 63.8 31.1 62.7 49.6 59.3 56.6 42.4 47.4 51.1 24.9 61.2 19.5 49.5 53.0 41.2 53.7 58.8 41.0 80.8 57.6 55.8 51.7 59.4 61.4 64.3 54.2 62.8 29.6 43.6 47.6 60.8 33.5 51.3 49.2 25.0 43.8 38.1 56.1 32.0 34.3 50.8 58.3 45.1 40.6 56.4 40.1 41.3 65.1 40.8 68.5 46.9 37.8 35.6 49.9 62.3 53.5 83.3 81.1 75.8 63.0 45.7 64.5 79.5 58.9 11.0 8.8 4.6 12.9 9.8 11.0 6.8 8.8 9.7 6.9 7.4 7.6 8.3 1.4 14.2 13.3 14.3 7.0 10.6 20.6 22.0 20.6 21.3 20.4 22.8 25.3 23.6 22.1 21.5 23.9 22.7 26.2 22.4 21.4 13.4 13.4 8.8 11.3 14.1 17.1 16.0 26.4 24.6 9.5 11.5 16.8 14.7 39.6 10.8 18.9 15.0 1.9 17.4 14.4 26.9 44.7 23.6 26.3 12.4 9.7 16.4 14.3 27.7 23.9 27.4 13.3 20.2 16.1 32.2 18.2 26.9 9.6 18.1 12.2 11.0 10.0 16.8 23.9 15.9 5.4 7.5 20.9 13.3 10.3 9.5 12.9 22.4 7.2 20.7 19.8 12.4 8.3 12.7 24.1 26.1 13.1 33.6 25.8 34.3 23.8 21.2 12.1 6.8 15.5 23.2 14.7 7.7 TXNDC8 "bA427L11.2, SPTRX-3, TRX6" ENSG00000204193 "Thioredoxin domain containing 8" Q6A555 9 110303476-110337884 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 101 "testis: 21.9" "Group enriched" "Detected in some" 182 "Early spermatids: 357.8;Late spermatids: 590.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "THP-1: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.50e-1)" "unprognostic (1.13e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 357.8 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 590.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TXNIP "ARRDC6, EST01027, HHCPA78, THIF, VDUP1" ENSG00000265972 "Thioredoxin interacting protein" Q9H3M7 1 145992435-145996579 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 2550.5;NK-cells: 2028.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 951.8;HSkMC: 1276.5;hTCEpi: 664.0;hTERT-RPE1: 781.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031085, HPA053694" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "HPA031085: AB_10601706, HPA053694: AB_2682232" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.92e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (2.51e-1)" "unprognostic (9.23e-2)" "unprognostic (1.20e-1)" "unprognostic (3.65e-2)" "unprognostic (1.19e-1)" "unprognostic (8.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (8.19e-2)" "unprognostic (2.22e-3)" 1542.7 466.8 130.3 566.5 159.9 404.7 1396.7 137.1 158.5 846.0 133.8 965.4 223.3 811.8 381.2 428.7 730.3 395.0 745.2 120.3 136.6 532.6 204.0 841.9 800.8 182.0 144.9 382.9 580.5 634.0 192.3 594.0 185.4 352.4 487.5 14.5 567.0 554.5 1446.1 1060.4 810.7 658.7 157.1 946.4 713.4 106.4 159.2 373.7 556.6 2306.2 1068.8 740.9 638.7 217.3 56.5 0.2 13.0 0.9 291.6 951.8 29.7 66.0 131.3 58.5 79.7 35.3 74.6 15.8 379.6 18.1 9.7 15.0 13.0 124.8 154.8 74.2 7.1 45.7 20.2 32.6 13.8 189.7 91.7 1276.5 664.0 119.0 206.7 781.9 23.2 61.8 184.8 121.2 30.2 76.5 31.9 180.2 36.3 112.5 48.5 28.5 107.8 498.3 151.6 122.8 61.7 99.9 283.1 80.5 239.0 26.2 29.1 266.6 56.5 160.1 10.0 304.2 108.7 169.3 170.7 13.8 39.3 86.6 86.3 1059.6 571.2 1219.2 792.2 551.3 729.8 519.3 668.8 710.4 334.4 542.4 650.2 708.5 1246.6 637.1 496.3 154.8 674.5 1684.4 130.3 159.9 137.1 158.5 120.3 136.6 182.0 144.9 185.4 157.1 159.2 217.3 2550.5 227.6 328.5 26.4 1360.4 70.7 236.9 129.8 413.8 6.5 167.4 111.2 526.0 185.8 184.4 272.2 29.2 5.0 1004.6 578.0 450.0 79.7 8.3 179.8 594.5 740.2 164.2 270.8 0.2 53.8 4.1 666.5 160.5 464.2 377.4 53.6 349.8 114.8 231.9 6.7 0.5 320.9 136.3 845.1 184.9 35.5 654.5 730.8 108.5 36.5 892.0 3.6 2028.9 45.2 55.8 225.7 459.4 447.2 639.6 370.7 79.0 169.3 155.8 3.7 1196.5 452.4 398.7 7.6 63.7 160.1 72.2 10.9 1142.8 303.9 186.9 516.2 TXNRD1 "GRIM-12, Trxr1, TXNR" ENSG00000198431 "Thioredoxin reductase 1" Q16881 12 104215779-104350307 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 459.7;Prostatic glandular cells: 557.4;Urothelial cells: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 1452.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001395, CAB004607, CAB015834, HPA043871" Approved Supported Nucleoplasm NA NA 6100000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB004607: AB_628405, CAB015834: , HPA001395: AB_1858377, HPA043871: AB_2678709" "unprognostic (2.52e-2)" "unprognostic (1.16e-1)" "unprognostic (5.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.18e-2)" "unprognostic (8.80e-2)" 47.1 148.1 22.5 40.6 21.1 64.7 28.0 20.9 22.6 28.0 37.3 50.9 58.4 47.9 21.0 30.7 39.0 55.9 65.8 21.1 29.8 37.9 46.5 63.0 34.4 55.2 26.7 34.1 19.0 33.8 21.2 39.1 33.3 41.0 45.6 20.1 20.8 60.6 67.8 12.4 39.4 51.6 22.9 27.8 52.1 37.8 24.6 42.8 30.4 64.0 34.1 141.6 30.1 25.7 228.4 1032.6 118.1 111.3 553.5 308.0 409.8 412.4 259.3 182.7 186.8 110.5 329.4 169.3 187.0 1452.6 682.1 77.7 235.7 158.6 214.1 82.7 101.8 143.1 765.8 468.0 885.7 226.3 149.9 176.9 159.8 403.7 128.1 557.1 634.0 227.9 200.5 77.5 276.8 109.1 233.4 102.7 114.4 453.0 1053.1 227.3 82.1 146.5 211.2 123.1 182.6 110.6 333.3 519.1 325.2 222.6 123.2 131.4 854.5 89.3 183.7 201.3 341.2 84.8 179.9 254.5 186.8 122.5 538.0 109.4 29.9 69.7 23.6 39.0 26.9 21.3 21.6 23.9 39.5 14.5 19.1 16.7 102.6 24.4 48.4 25.2 19.8 27.6 22.5 21.1 20.9 22.6 21.1 29.8 55.2 26.7 33.3 22.9 24.6 25.7 26.0 64.1 67.5 50.3 27.6 104.0 459.7 41.3 40.9 28.1 19.4 16.3 66.2 32.9 79.3 16.5 22.9 26.1 40.4 93.4 41.1 79.6 45.0 100.9 36.8 116.2 20.4 46.3 48.2 80.7 34.3 90.1 69.8 119.6 53.2 35.2 49.2 68.2 42.0 28.6 56.7 18.8 44.7 43.5 100.5 19.1 68.0 62.2 19.6 49.6 51.9 24.8 26.8 29.1 55.3 197.7 40.5 29.3 28.4 557.4 24.6 37.5 105.5 20.9 0.0 43.4 84.0 14.4 33.8 24.3 72.9 51.3 28.5 98.4 33.0 488.0 TYMP "ECGF1, MNGIE" ENSG00000025708 "Thymidine phosphorylase" P19971 22 50525752-50530032 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Glycosyltransferase, Growth factor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 643.9;Hofbauer cells: 477.4;Macrophages: 561.7;monocytes: 2174.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 135.8;eosinophil: 74.9;intermediate monocyte: 98.4;myeloid DC: 39.5;neutrophil: 114.1;non-classical monocyte: 77.1" "Group enriched" "Detected in all" 10 "dendritic cells: 39.5;granulocytes: 114.1;monocytes: 135.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 40.0;HHSteC: 95.2;Karpas-707: 68.6;U-266/70: 68.6" "Not detected" "Not detected" "HPA000530, HPA001072, CAB002518" Enhanced Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 11000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nuclear bodies, Golgi apparatus" Cytosol "CAB002518: AB_563953, HPA000530: AB_2666017, HPA001072: AB_1080274" "unprognostic (7.02e-3)" "unprognostic (1.00e-1)" "unprognostic (3.61e-1)" "prognostic favorable (4.34e-5)" "unprognostic (7.60e-2)" "unprognostic (1.16e-2)" "unprognostic (2.40e-1)" "unprognostic (7.17e-2)" "unprognostic (4.64e-2)" "unprognostic (1.33e-1)" "unprognostic (3.31e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (3.50e-8)" "unprognostic (1.32e-1)" "unprognostic (4.02e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" 46.8 19.5 6.1 77.7 6.0 22.0 37.9 7.1 7.9 32.2 12.7 20.4 26.1 7.8 0.5 58.5 30.0 7.2 26.7 6.4 8.6 38.2 82.0 63.4 31.5 22.1 18.3 4.0 13.8 4.5 8.8 15.4 15.9 21.0 3.6 0.0 40.0 5.6 10.7 24.5 32.5 9.1 10.9 86.1 31.2 3.0 18.0 15.6 25.4 1.6 15.3 22.9 27.0 12.2 27.0 2.5 0.4 0.8 1.8 2.2 5.1 3.7 0.5 6.1 17.4 0.1 40.0 1.8 4.1 5.8 1.3 21.0 0.2 1.0 0.0 9.0 16.5 1.8 3.9 3.5 95.2 1.3 26.9 4.7 4.6 5.4 0.0 0.1 0.1 0.5 2.8 68.6 0.9 1.9 1.5 9.9 0.6 1.9 9.1 5.7 0.4 35.1 0.3 1.2 0.7 5.6 22.9 17.3 6.5 0.2 4.2 13.8 6.7 0.8 4.7 1.5 1.5 68.6 15.9 5.7 1.9 1.5 1.6 19.5 135.8 74.9 2.0 98.4 1.2 6.7 2.9 1.2 39.5 6.9 1.6 1.3 114.1 9.5 77.1 9.3 3.1 10.1 6.1 6.0 7.1 7.9 6.4 8.6 22.1 18.3 15.9 10.9 18.0 12.2 122.6 12.8 29.0 0.3 122.9 58.5 57.4 169.9 53.5 3.4 101.5 90.8 3.2 50.1 88.6 33.1 4.2 17.2 65.8 154.8 29.4 340.2 2.2 55.7 56.0 55.7 16.8 19.6 0.3 643.9 300.8 81.9 38.7 59.2 53.4 3.0 38.2 93.0 477.4 0.0 0.4 50.2 24.4 371.8 409.4 8.7 5.0 561.7 113.8 4.7 2174.6 2.9 71.1 0.5 0.2 364.0 86.4 1.9 102.1 109.8 214.5 105.1 78.0 6.6 26.3 93.3 62.4 1.5 8.0 71.7 56.7 33.5 62.5 3.7 51.1 76.0 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657653-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.5;lymphoid tissue: 113.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 105.8;Erythroid cells: 189.3;Extravillous trophoblasts: 115.3;Plasma cells: 112.7;Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.1" "Group enriched" "Detected in many" 6 "NK-cells: 6.7;T-cells: 14.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002784, HPA074922" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB002784: , HPA074922: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 4.5 3.1 4.3 24.2 7.5 88.5 6.7 4.1 6.5 4.8 2.7 22.9 10.5 5.1 1.3 14.8 5.6 3.8 2.2 5.0 4.9 6.5 11.8 4.9 36.1 4.9 5.2 2.1 3.6 1.8 1.6 22.3 4.4 3.1 27.1 4.2 3.9 2.0 0.4 6.2 14.8 12.7 4.8 10.6 8.8 34.3 6.1 113.6 2.1 0.4 44.5 8.4 5.5 10.3 102.7 156.6 320.4 154.9 35.1 57.9 159.9 238.9 141.1 251.7 299.9 132.8 80.1 160.0 91.5 129.9 143.2 45.1 225.3 89.7 216.1 152.3 244.9 273.1 135.8 229.4 8.2 564.8 286.5 51.5 20.7 159.6 49.6 48.4 214.4 334.0 222.0 249.6 321.8 118.1 687.7 311.4 114.7 124.3 114.0 446.8 287.0 191.3 95.6 88.9 106.0 175.7 201.4 91.6 61.1 197.3 63.5 253.5 85.0 289.7 569.5 267.3 474.2 305.9 405.2 367.3 75.2 240.6 339.2 0.0 0.0 1.3 1.1 0.1 0.0 1.1 2.8 2.2 1.8 0.0 0.0 0.6 0.7 6.7 0.1 0.3 14.1 2.9 4.3 7.5 4.1 6.5 5.0 4.9 4.9 5.2 4.4 4.8 6.1 10.3 2.1 0.0 2.3 1.6 15.7 14.4 15.9 13.0 27.9 0.5 7.8 11.7 3.6 2.8 6.7 0.0 0.0 105.8 14.5 15.5 1.9 2.3 34.4 5.6 8.4 12.5 1.2 189.3 0.4 0.8 115.3 28.3 14.3 7.4 7.0 76.2 6.8 4.3 71.4 0.0 0.6 20.9 10.2 15.6 19.4 31.9 6.2 10.7 10.6 1.0 3.9 45.0 5.2 0.5 15.6 1.5 8.9 3.8 112.7 5.0 13.8 36.6 1.0 2.4 13.1 1.3 32.6 180.8 30.7 48.0 7.2 27.0 21.3 10.5 54.9 18.7 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;ovary: 49.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.4;Leydig cells: 44.4;Oligodendrocyte precursor cells: 29.1;Oligodendrocytes: 46.8;Peritubular cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 17000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 21.5 3.5 18.2 1.4 30.3 0.8 5.2 17.7 27.1 2.1 0.0 2.3 1.6 4.6 3.5 13.1 11.5 2.5 2.2 27.7 10.7 11.3 0.8 3.3 1.3 20.9 22.6 49.7 9.8 0.9 0.9 5.7 18.6 2.6 0.9 2.6 1.9 6.1 0.9 13.8 2.4 4.4 14.4 5.5 3.2 18.8 15.7 0.4 1.1 1.8 3.7 2.1 4.1 32.0 10.3 6.7 20.7 22.7 18.9 12.8 69.2 14.6 9.3 14.2 13.1 37.7 3.4 0.4 18.3 11.9 19.9 23.7 23.3 3.6 6.5 5.8 15.5 3.2 20.2 18.1 13.3 5.2 0.4 4.1 7.3 10.9 3.6 5.8 10.6 9.8 19.1 4.3 7.9 9.8 2.4 1.0 47.7 16.0 6.7 31.9 18.6 3.8 1.2 19.7 24.6 7.0 13.7 21.6 16.3 29.8 17.8 6.0 8.4 28.0 12.2 21.0 22.5 1.7 3.5 3.1 17.2 33.8 17.2 1.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.2 0.2 1.5 0.3 0.1 0.3 0.1 0.1 18.2 30.3 17.7 27.1 27.7 10.7 20.9 22.6 18.6 14.4 15.7 32.0 3.4 3.2 1.1 17.6 0.9 6.8 8.5 0.4 0.6 2.7 2.2 2.2 2.9 2.8 0.7 3.7 6.2 2.9 1.1 1.3 0.0 3.9 3.6 1.1 13.0 5.4 1.8 0.0 42.4 3.6 10.2 10.5 8.6 1.9 0.0 7.6 9.7 0.4 1.2 0.0 4.6 0.9 0.0 1.9 1.3 5.1 44.4 0.9 8.8 1.0 0.1 8.3 1.0 29.1 46.8 4.6 0.1 47.0 0.3 6.4 1.2 1.2 0.5 4.0 0.0 3.9 4.3 4.0 6.5 4.2 10.9 18.9 0.7 5.8 2.3 5.7 U2AF1 "RN, RNU2AF1, U2AF35, U2AFBP" ENSG00000160201 "U2 small nuclear RNA auxiliary factor 1" Q01081 21 43092956-43107570 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 492.9;Basal respiratory cells: 406.9;Ionocytes: 266.5;Langerhans cells: 374.7;Suprabasal keratinocytes: 433.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 607.7" "Low region specificity" "Detected in all" "HPA044833, HPA052083" Supported Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA044833: AB_10960990, HPA052083: AB_2681720" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (5.98e-2)" "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (8.06e-2)" "unprognostic (2.76e-2)" "unprognostic (4.29e-4)" "unprognostic (4.81e-4)" "unprognostic (3.42e-2)" "unprognostic (2.31e-3)" "unprognostic (8.85e-2)" "unprognostic (2.14e-6)" "unprognostic (1.08e-1)" "unprognostic (1.40e-2)" "unprognostic (1.72e-1)" "unprognostic (1.26e-2)" 62.9 47.6 36.8 31.1 39.9 85.9 58.7 39.8 46.9 57.6 38.0 79.3 25.8 68.9 27.8 64.3 60.8 18.7 43.0 37.7 41.1 42.8 48.0 57.3 45.2 39.3 40.2 69.3 41.8 32.7 60.1 34.6 38.5 48.0 26.8 28.9 49.1 40.8 74.9 47.5 57.2 35.8 38.3 65.4 58.2 54.4 38.8 61.8 62.6 24.8 55.9 60.7 50.7 40.8 101.1 27.7 250.5 71.3 28.7 38.8 248.1 88.2 82.4 105.4 115.3 486.0 59.8 20.8 35.1 54.3 125.6 33.0 161.1 36.3 104.9 114.6 134.0 607.7 61.2 117.9 77.0 264.0 115.2 45.5 90.6 177.1 100.6 43.5 62.8 238.0 105.8 113.4 97.2 324.4 271.1 358.1 287.6 123.4 108.3 485.1 166.9 211.9 99.8 15.4 125.9 77.6 212.6 98.6 147.6 36.5 125.5 147.5 12.1 79.2 59.6 82.0 236.3 191.4 178.3 48.8 80.3 333.6 118.6 211.9 141.0 153.1 101.2 140.4 106.7 140.2 112.7 95.5 150.4 134.2 112.9 109.1 213.1 93.1 196.9 240.7 149.3 188.7 36.8 39.9 39.8 46.9 37.7 41.1 39.3 40.2 38.5 38.3 38.8 40.8 9.5 19.2 18.1 3.9 37.8 492.9 32.5 406.9 86.6 23.9 5.7 2.8 5.0 17.2 153.5 1.8 43.8 19.5 15.3 16.5 1.9 5.2 3.1 4.2 4.4 51.7 18.2 45.0 5.2 6.0 20.7 51.8 44.4 4.2 28.4 3.8 31.8 16.2 23.2 18.5 4.6 17.0 266.5 33.0 374.7 4.1 18.3 30.6 202.7 4.7 19.3 13.0 27.8 3.0 6.2 4.8 17.0 22.6 60.3 31.1 43.2 3.1 107.6 60.7 6.6 39.1 110.7 16.4 18.9 79.8 433.6 23.8 46.6 1.3 20.2 39.1 UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm NA NA 14000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.21e-2)" 98.4 157.9 102.9 98.3 113.2 94.3 98.6 103.4 115.5 127.9 133.9 101.1 71.3 127.1 64.3 155.3 119.3 64.9 117.4 106.2 102.0 131.2 114.7 109.5 105.0 106.9 104.2 136.5 89.0 107.5 135.2 67.4 109.3 103.2 68.5 95.6 119.5 78.9 201.1 119.5 100.4 117.4 94.4 131.9 98.6 98.7 110.0 119.7 160.1 114.1 110.8 101.1 124.8 121.3 269.1 273.2 307.7 471.9 207.4 186.8 135.0 175.1 187.1 248.6 200.5 219.3 201.3 201.6 111.8 357.0 361.5 254.9 392.9 375.7 180.9 163.4 391.7 126.1 295.2 180.0 145.1 215.2 258.8 177.4 193.2 362.7 279.4 176.7 330.2 236.1 138.9 173.7 250.4 343.4 203.3 188.5 329.6 163.2 417.1 233.1 215.3 343.7 198.7 287.0 197.4 148.1 520.8 250.9 116.9 329.9 349.5 130.3 241.6 183.1 210.7 266.4 166.1 117.6 132.8 286.3 189.4 150.8 224.9 31.0 39.7 40.7 39.4 51.1 34.0 39.8 31.8 35.0 43.2 29.9 24.7 31.1 44.8 38.1 49.7 29.3 40.3 39.9 102.9 113.2 103.4 115.5 106.2 102.0 106.9 104.2 109.3 94.4 110.0 121.3 37.2 51.3 34.7 45.1 37.1 33.6 38.6 55.7 26.2 24.9 48.3 39.6 51.4 51.5 50.0 82.8 16.7 46.3 34.2 133.1 35.2 77.5 29.6 84.9 56.3 40.9 57.5 33.2 27.1 90.8 68.7 45.0 74.9 97.5 18.3 60.3 43.5 51.2 60.0 11.8 35.5 78.6 30.5 49.0 37.8 61.6 42.3 51.4 19.6 31.9 57.7 20.7 13.4 32.2 46.5 147.9 74.7 65.8 44.0 55.2 82.2 61.6 56.4 25.1 39.5 38.8 56.6 10.5 34.0 51.3 42.1 71.1 34.6 56.8 68.2 55.4 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2I UBC9 ENSG00000103275 "Ubiquitin conjugating enzyme E2 I" P63279 16 1308880-1327018 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003909, CAB009021, CAB079920" Approved Supported Nucleoplasm,Nucleoli NA NA 130000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "CAB009021: AB_2210610, CAB079920: AB_2809487, HPA003909: AB_1858529" "unprognostic (2.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.55e-2)" "unprognostic (3.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.88e-3)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (7.60e-3)" "unprognostic (3.56e-1)" "unprognostic (7.28e-2)" "unprognostic (9.30e-2)" "unprognostic (1.57e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.15e-3)" 62.5 76.3 42.5 60.3 44.0 81.6 62.0 46.1 49.3 64.7 37.1 63.8 45.1 72.7 48.7 74.2 67.3 34.3 68.2 45.2 45.2 63.4 40.8 53.1 76.0 39.3 42.3 93.1 49.1 72.0 61.6 58.1 40.2 53.4 47.3 31.7 56.4 46.7 58.0 68.0 61.1 53.8 42.2 71.9 52.9 47.6 47.1 110.3 53.2 57.0 89.3 66.6 63.1 42.1 121.3 161.1 269.0 157.7 112.7 135.8 114.4 170.0 121.7 154.3 152.9 191.8 190.1 208.2 137.7 148.1 140.7 142.4 193.2 159.2 197.9 151.2 133.4 130.6 136.6 188.4 178.6 194.9 148.0 127.1 100.7 152.1 180.0 149.0 170.0 169.9 190.3 124.3 148.0 254.4 349.6 193.0 219.0 136.0 118.5 434.0 170.9 238.4 145.7 106.6 150.3 159.8 149.3 164.1 177.7 152.8 167.5 234.4 139.4 149.2 172.6 134.0 155.5 132.1 170.4 423.4 85.3 142.9 164.7 278.7 214.3 327.1 165.9 256.6 200.9 297.8 167.8 170.3 214.7 241.1 148.2 149.6 149.5 202.6 249.5 186.3 196.5 260.9 42.5 44.0 46.1 49.3 45.2 45.2 39.3 42.3 40.2 42.2 47.1 42.1 109.5 51.3 67.0 16.3 172.8 178.6 186.4 275.6 97.3 64.6 101.9 105.7 89.1 84.4 140.9 62.5 50.1 312.8 153.9 77.4 105.7 211.9 64.4 66.6 100.6 118.3 102.3 127.4 17.2 148.2 293.1 134.4 55.5 104.6 109.5 149.7 94.2 43.7 213.5 47.1 16.8 97.1 162.8 104.8 182.1 37.8 129.8 124.8 128.1 15.9 220.2 104.7 209.1 16.6 26.7 212.3 91.8 107.6 144.1 294.8 90.4 117.7 65.7 63.1 78.9 82.1 185.4 139.6 145.7 158.4 206.7 418.1 144.7 134.9 134.7 304.5 UBE2N "MGC8489, UBC13, UbcH-ben" ENSG00000177889 "Ubiquitin conjugating enzyme E2 N" P61088 12 93405673-93441947 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 15 "Early spermatids: 2532.0;Late spermatids: 8141.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044976 Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 1800000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Nucleoli fibrillar center" "HPA044976: AB_2679163" "unprognostic (1.74e-2)" "unprognostic (5.53e-1)" "unprognostic (1.26e-2)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (8.09e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (8.49e-3)" "unprognostic (2.72e-1)" "unprognostic (4.28e-3)" "unprognostic (1.07e-1)" "unprognostic (9.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.48e-1)" "unprognostic (1.30e-3)" 52.4 48.6 46.4 62.1 49.9 69.9 41.6 40.3 51.6 35.8 26.8 55.9 42.5 44.0 38.3 60.4 37.3 33.5 57.6 50.8 53.2 54.4 45.5 38.2 80.0 45.2 43.9 31.3 30.6 40.4 32.6 49.5 52.2 46.0 44.0 50.3 36.0 34.5 83.0 41.3 42.3 42.7 44.3 42.9 41.0 186.9 44.3 79.4 29.0 70.3 73.8 76.4 38.6 44.4 190.3 133.2 221.1 142.6 82.9 81.4 154.5 259.4 135.6 201.0 167.3 239.8 80.0 380.2 57.3 151.1 133.8 147.7 245.2 188.7 189.7 323.3 128.4 258.0 66.6 214.2 106.4 311.9 165.1 86.3 75.2 120.8 148.9 143.1 157.3 146.9 292.8 58.0 210.9 155.3 310.4 286.2 288.9 165.9 189.4 237.3 179.9 186.6 170.1 280.9 214.9 195.6 136.1 158.5 130.0 118.7 207.5 188.0 165.8 135.7 114.6 124.1 189.9 99.5 289.4 324.0 53.5 162.5 170.2 133.7 89.5 101.3 99.3 123.3 116.8 174.0 124.8 124.1 119.6 144.7 109.3 104.9 27.7 106.0 141.7 89.6 198.6 202.5 46.4 49.9 40.3 51.6 50.8 53.2 45.2 43.9 52.2 44.3 44.3 44.4 87.5 38.5 45.8 24.8 151.4 322.2 231.3 219.1 92.2 72.1 84.3 60.5 74.6 60.1 112.2 90.1 27.1 236.0 104.3 76.3 191.7 141.4 2532.0 79.7 79.0 95.3 74.7 75.9 44.6 99.0 226.0 100.9 49.5 96.5 93.8 68.3 55.3 55.3 165.6 87.5 49.0 78.6 187.2 67.8 216.3 8141.3 93.8 97.0 147.7 33.7 152.9 111.9 79.3 38.7 42.1 135.5 83.8 86.1 113.3 218.2 61.2 171.3 88.9 57.6 46.0 101.9 146.2 338.4 227.6 142.2 322.5 284.7 128.2 86.4 94.9 260.3 UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102252273-102412759 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 239.9;Excitatory neurons: 214.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA053688: AB_2682230" "unprognostic (3.79e-3)" "unprognostic (7.44e-3)" "unprognostic (1.25e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (2.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.54e-3)" "unprognostic (8.29e-3)" "unprognostic (3.84e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" 33.0 18.3 16.6 22.4 19.4 36.5 30.9 26.5 24.0 25.6 23.4 33.3 14.9 29.6 23.7 27.5 26.1 17.3 25.8 17.3 16.0 17.5 17.7 29.8 33.6 16.0 16.1 32.2 25.7 30.4 24.4 17.8 15.7 20.0 17.0 45.4 26.1 20.7 50.1 35.6 27.2 17.2 13.7 24.2 25.0 43.9 16.6 43.0 21.0 29.6 28.6 28.2 26.4 18.9 64.5 28.4 53.2 27.5 51.8 52.2 48.9 47.4 41.9 36.6 31.7 28.3 42.1 127.1 39.8 44.5 23.7 38.2 46.2 41.1 51.1 55.3 22.7 106.5 39.7 52.2 46.1 33.7 56.3 60.1 40.4 37.5 64.5 41.5 44.6 35.6 52.3 70.2 34.8 58.0 85.3 40.3 40.1 61.8 31.6 49.3 31.6 60.9 33.5 62.3 39.1 32.5 33.4 31.8 34.3 46.1 51.4 35.1 44.6 38.5 44.9 35.1 33.5 37.3 38.7 129.5 38.0 51.2 32.0 1.8 1.5 2.4 2.4 1.5 2.4 2.1 2.5 2.5 1.8 1.7 2.0 3.0 3.0 1.1 2.7 1.6 3.4 1.0 16.6 19.4 26.5 24.0 17.3 16.0 16.0 16.1 15.7 13.7 16.6 18.9 51.4 25.6 31.7 239.9 44.8 52.3 41.2 26.3 55.8 52.0 37.3 29.6 39.8 8.6 49.9 31.3 68.8 27.7 36.2 20.9 9.8 18.8 38.6 47.5 47.0 40.1 33.4 33.2 214.2 15.0 18.9 43.7 37.8 69.0 29.8 64.3 22.9 19.0 17.0 57.2 191.7 19.5 26.4 31.4 52.6 23.6 39.7 43.7 44.4 129.3 43.5 31.3 26.8 196.6 174.0 21.4 18.3 36.5 65.9 45.2 18.3 9.0 46.5 44.8 13.1 66.3 48.4 59.4 30.2 46.8 61.1 69.6 46.9 30.8 19.5 53.5 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "intestine: 201.2;liver: 322.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 105.0" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HaCaT: 14.0;OE19: 64.5;RT4: 34.7" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.1 0.6 0.2 0.5 0.5 0.2 1.5 0.8 0.1 0.2 3.0 201.2 0.2 0.4 3.5 0.1 1.0 0.2 0.4 0.8 4.0 322.4 0.2 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 2.4 0.9 0.5 0.3 0.1 1.8 79.2 0.1 0.0 0.2 2.4 0.6 0.3 0.1 0.2 0.1 0.3 10.0 0.9 0.6 0.3 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.0 0.0 0.1 5.4 0.3 0.2 2.5 0.1 0.1 14.0 0.0 0.2 0.0 0.2 0.1 0.1 0.6 1.6 0.0 0.5 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.3 0.2 0.6 0.0 0.8 0.1 0.3 0.5 64.5 6.5 0.1 0.1 0.6 0.0 34.7 0.2 0.4 2.6 0.4 0.0 0.2 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.2 0.1 0.7 0.4 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 1.4 0.3 0.1 0.1 0.1 0.0 0.6 0.5 1.5 0.8 0.4 0.8 0.2 0.2 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.1 105.0 0.0 0.0 0.0 0.4 0.0 2.4 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.1 6.9 14.6 2.2 1.5 0.0 0.0 0.4 0.1 0.2 0.1 1.5 0.0 0.0 0.1 0.0 0.7 7.3 UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636454-233773305 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 22.0;intestine: 79.5;stomach 1: 32.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1.8;Gastric mucus-secreting cells: 3.6;Intestinal goblet cells: 1.0;Paneth cells: 1.4;Proximal enterocytes: 3.9;Squamous epithelial cells: 4.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 143 "RT4: 523.3" "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 49.5 79.5 0.1 0.0 14.6 0.0 22.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 36.5 0.0 0.9 0.0 0.0 0.9 53.1 1.9 0.0 0.0 32.7 1.5 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 1.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 523.3 0.0 0.1 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 UGT1A3 UGT1C ENSG00000243135 "UDP glucuronosyltransferase family 1 member A3" P35503 2 233729108-233773299 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 73.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HaCaT: 11.4" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.15e-2)" "unprognostic (9.93e-2)" "unprognostic (2.97e-1)" "unprognostic (4.59e-2)" "unprognostic (1.04e-4)" "unprognostic (8.22e-2)" "unprognostic (2.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 73.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A4 "HUG-BR2, UGT1D" ENSG00000244474 "UDP glucuronosyltransferase family 1 member A4" P22310 2 233718736-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 391.7" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 15.1" "Cancer enriched" "Detected in single" 487 "liver cancer: 24.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (9.89e-3)" "unprognostic (6.77e-5)" "unprognostic (2.59e-1)" "unprognostic (3.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 391.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A9 "HLUGP4, LUGP4, UGT1AI" ENSG00000241119 "UDP glucuronosyltransferase family 1 member A9" O60656 2 233671898-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 370 "kidney: 458.6;liver: 195.6" "Group enriched" "Detected in some" 11 "Hepatocytes: 7.5;Proximal tubular cells: 6.6" "Group enriched" "Detected in some" 157 "liver cancer: 16.1;renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "A549: 1.4;RT4: 1.2" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.46e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (5.04e-5)" "unprognostic (4.26e-2)" "unprognostic (1.60e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 458.6 195.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UHRF1BP1L KIAA0701 ENSG00000111647 "UHRF1 binding protein 1 like" A0JNW5 12 100028455-100142874 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039671, HPA075150" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Cytosol" "HPA039671: AB_10794201, HPA075150: " "unprognostic (4.80e-2)" "unprognostic (3.17e-1)" "unprognostic (2.34e-2)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (7.36e-2)" "unprognostic (8.10e-2)" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (5.43e-2)" "unprognostic (1.88e-2)" "unprognostic (2.53e-1)" "unprognostic (2.94e-3)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-2)" "unprognostic (1.28e-2)" 8.7 10.9 6.2 10.2 7.7 32.9 8.8 11.0 11.5 7.2 9.9 8.3 8.4 7.5 7.0 7.0 6.3 8.9 7.9 13.2 6.2 12.3 24.6 7.7 9.2 4.9 5.4 7.5 3.8 13.6 5.2 9.0 4.8 9.0 7.9 14.6 6.4 8.0 19.8 5.9 7.1 8.8 4.6 9.2 6.0 14.0 3.7 8.4 10.9 14.6 7.0 10.1 5.2 9.2 18.6 19.7 10.8 11.2 16.4 23.1 21.6 28.3 28.4 22.4 16.3 14.8 6.2 16.0 7.2 29.1 13.1 6.9 20.4 9.7 21.5 42.7 10.0 10.7 14.1 17.3 15.1 20.4 16.8 13.1 8.0 27.0 18.6 20.7 16.0 11.0 8.6 16.2 22.1 10.3 13.1 17.5 18.7 6.3 17.7 14.7 19.2 15.7 11.4 32.2 18.3 11.4 21.4 24.5 8.5 9.2 21.9 23.0 12.7 24.6 13.2 21.5 20.1 19.1 35.2 22.3 12.4 15.1 15.2 21.6 11.4 7.8 3.6 12.3 5.3 5.5 4.0 4.1 12.8 4.5 3.4 4.2 33.9 5.9 10.9 7.6 5.2 5.4 6.2 7.7 11.0 11.5 13.2 6.2 4.9 5.4 4.8 4.6 3.7 9.2 10.6 28.9 8.7 27.1 18.2 12.7 17.2 5.0 19.9 11.9 9.3 7.5 15.7 1.5 12.6 9.2 4.2 4.7 15.0 10.9 5.9 6.0 35.1 15.7 23.7 8.6 5.4 9.4 75.2 5.9 8.9 24.7 7.7 9.9 24.1 6.3 5.3 18.5 11.2 15.2 54.2 2.1 4.1 23.3 21.4 5.3 7.2 29.5 10.6 45.0 25.7 8.3 8.2 37.2 29.5 5.9 7.4 7.9 12.5 18.5 8.9 14.9 21.8 12.0 0.0 23.3 15.1 24.1 19.1 14.9 11.6 10.9 15.7 8.3 5.7 11.9 USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.8;kidney: 54.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 190.0;Muller glia cells: 163.6;Paneth cells: 203.0;Proximal enterocytes: 430.7;Proximal tubular cells: 190.3;Undifferentiated cells: 115.7" "Group enriched" "Detected in many" 7 "colorectal cancer: 34.5;pancreatic cancer: 18.8;renal cancer: 29.4;stomach cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 60.6;HeLa: 21.8;OE19: 57.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "CAB013690: , HPA027398: AB_10601775, HPA027492: AB_10601898, HPA028033: AB_10601782" "unprognostic (3.60e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-2)" "unprognostic (9.65e-2)" "prognostic favorable (9.41e-4)" "unprognostic (1.29e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" 0.4 0.3 2.8 5.9 6.8 0.0 0.2 2.8 3.9 0.1 1.5 51.5 97.8 0.1 0.3 0.0 2.9 25.9 0.1 9.0 4.7 54.0 0.6 0.1 0.1 6.1 5.7 0.0 3.9 0.0 6.7 0.0 7.0 0.0 48.3 19.0 0.0 0.3 0.0 0.0 96.5 2.1 4.1 0.0 26.7 0.2 5.9 0.1 1.1 0.0 0.0 0.6 0.1 8.3 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 60.6 8.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 21.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 6.8 2.8 3.9 9.0 4.7 6.1 5.7 7.0 4.1 5.9 8.3 0.0 0.0 0.0 18.3 1.6 0.0 0.1 0.0 0.0 0.7 0.0 1.3 0.6 52.9 0.7 5.5 2.1 0.0 0.0 190.0 21.5 20.5 1.0 1.7 0.0 0.4 64.0 0.0 0.6 27.5 0.0 0.3 53.5 0.0 4.5 0.0 0.0 0.0 0.0 1.7 0.2 92.9 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 163.6 0.0 0.5 36.4 56.0 203.0 0.0 0.2 0.0 430.7 190.3 1.0 4.9 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.8 0.1 115.7 0.1 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116032-5175034 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 19.6;testis: 13.4" "Cell type enhanced" "Detected in many" "Early spermatids: 24.4;Spermatocytes: 26.9" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046969 Uncertain Vesicles NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.4 0.3 0.2 0.2 0.5 0.1 0.7 0.3 0.6 1.4 1.5 0.8 0.0 0.9 0.7 0.2 0.5 0.5 0.4 0.4 0.3 0.6 0.1 0.4 0.3 0.7 0.2 2.6 0.3 0.0 0.6 0.5 0.6 0.6 0.3 2.5 0.5 0.4 19.6 0.6 0.3 0.9 0.2 0.4 0.2 13.4 0.5 0.0 0.9 0.6 0.2 0.3 0.5 0.9 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.4 0.3 0.1 0.1 0.0 0.3 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.3 0.6 0.4 0.3 0.7 0.2 0.6 0.2 0.5 0.9 2.0 6.4 10.8 0.0 0.4 10.8 1.0 1.1 0.0 8.5 4.0 3.8 1.6 5.7 3.5 3.7 12.5 0.6 1.0 0.1 3.9 0.0 24.4 1.1 2.1 3.0 0.0 5.3 1.2 0.0 0.8 1.8 0.0 1.4 0.0 1.2 3.6 3.2 2.7 1.7 1.0 0.0 0.0 5.4 6.4 13.5 1.8 3.1 3.6 2.8 3.2 5.1 0.0 0.0 2.9 0.1 0.1 2.6 0.1 2.1 0.0 3.2 4.0 12.3 6.6 5.9 1.7 26.9 11.5 0.0 10.4 0.7 1.1 0.9 0.2 1.1 USP8 "HumORF8, KIAA0055, SPG59, UBPY" ENSG00000138592 "Ubiquitin specific peptidase 8" P40818 15 50424380-50514421 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050215 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Cytosol "HPA050215: AB_2681054" "unprognostic (5.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.46e-1)" "unprognostic (9.58e-2)" "unprognostic (2.35e-2)" "unprognostic (2.91e-1)" "unprognostic (1.42e-1)" "unprognostic (3.96e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (2.94e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.89e-2)" "unprognostic (1.13e-1)" "unprognostic (3.79e-1)" "unprognostic (1.58e-1)" 20.3 18.8 11.5 21.1 11.0 27.6 19.6 14.4 13.3 20.5 18.1 21.5 26.7 19.1 10.4 20.7 18.5 16.4 15.1 9.1 14.6 27.0 28.1 19.5 19.0 14.1 13.1 19.9 17.4 45.1 10.6 20.3 12.5 17.0 20.8 22.2 19.8 17.2 17.6 14.2 24.4 18.4 11.5 18.7 22.5 32.0 13.6 20.9 25.4 22.7 24.3 20.0 12.6 13.2 30.6 35.8 23.7 41.1 32.3 44.3 31.0 45.7 43.9 35.7 40.4 19.5 17.7 28.8 35.0 43.5 46.6 57.8 28.8 28.3 39.9 27.2 19.3 52.9 31.9 27.3 35.9 34.3 34.4 32.4 36.2 26.0 55.8 37.0 36.3 23.3 28.4 36.8 32.9 45.9 26.6 12.0 28.5 32.6 17.1 24.1 39.1 45.8 29.5 61.3 29.1 23.8 42.5 55.9 57.4 48.9 35.8 36.9 45.0 41.1 24.1 122.7 52.7 28.5 69.8 32.4 30.6 65.6 40.1 114.6 27.7 50.1 21.4 26.1 22.1 37.3 22.9 23.3 22.7 34.3 24.0 21.2 47.9 22.1 35.0 20.5 20.0 16.0 11.5 11.0 14.4 13.3 9.1 14.6 14.1 13.1 12.5 11.5 13.6 13.2 63.5 96.1 130.8 36.2 101.8 28.9 40.7 47.3 35.9 54.5 41.7 40.0 69.8 51.5 72.7 47.8 68.8 59.0 92.7 79.5 25.4 53.7 153.7 91.5 79.7 53.8 53.3 36.8 41.0 51.3 45.4 55.8 58.1 65.6 86.7 48.5 51.0 56.6 45.4 33.7 44.3 68.7 36.7 73.2 38.2 28.4 53.7 77.6 40.9 46.9 85.3 45.5 72.1 34.7 46.1 57.3 58.2 61.7 87.1 51.0 88.9 49.9 114.9 74.2 46.0 108.2 56.2 140.5 54.8 39.6 41.5 105.2 72.6 77.1 64.8 55.3 VAMP3 CEB ENSG00000049245 "Vesicle associated membrane protein 3" Q15836 1 7771296-7781432 "Cancer-related genes, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 260000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.09e-2)" "unprognostic (4.03e-1)" "unprognostic (3.39e-3)" "unprognostic (2.95e-1)" "unprognostic (9.15e-3)" "unprognostic (3.86e-3)" "unprognostic (9.49e-3)" "unprognostic (2.00e-1)" "unprognostic (7.16e-2)" "unprognostic (2.36e-1)" "unprognostic (1.83e-3)" "unprognostic (2.17e-1)" "prognostic favorable (2.36e-4)" "unprognostic (1.02e-1)" "unprognostic (2.85e-1)" "unprognostic (9.52e-2)" "unprognostic (3.30e-2)" 108.3 79.2 81.8 50.1 102.7 113.4 76.8 101.2 102.7 73.9 70.8 67.9 63.4 74.1 66.1 82.1 65.1 64.7 78.6 78.7 91.3 77.0 63.6 91.7 44.0 111.4 102.3 78.2 33.0 74.0 46.8 87.1 111.1 60.2 74.1 26.2 45.7 81.7 89.4 71.0 69.7 85.5 97.2 56.7 60.6 43.8 93.6 37.1 67.9 98.9 52.3 86.4 60.8 123.6 92.3 64.3 67.9 81.4 181.9 204.1 47.7 162.5 183.3 170.8 160.5 70.8 116.1 12.1 89.1 205.8 86.9 78.5 75.2 109.9 218.1 9.6 93.5 59.2 56.8 99.3 118.0 35.4 56.2 167.2 80.7 121.8 98.7 168.4 209.6 26.8 61.9 54.5 241.7 41.2 26.7 31.5 30.0 102.9 111.6 21.9 98.7 37.4 133.7 52.4 18.6 70.8 141.2 68.5 152.2 81.1 69.4 37.3 186.9 152.5 52.3 160.0 79.4 44.7 65.2 35.1 174.7 140.9 122.9 63.7 63.0 63.0 15.9 71.7 16.5 13.8 14.9 14.1 43.1 11.2 11.9 13.0 84.0 19.0 65.0 14.0 20.9 30.2 81.8 102.7 101.2 102.7 78.7 91.3 111.4 102.3 111.1 97.2 93.6 123.6 88.0 48.1 46.1 11.8 18.6 43.6 58.2 38.8 50.1 12.5 30.5 29.1 44.8 37.1 31.8 40.5 4.2 85.6 24.2 60.1 64.6 67.9 24.3 24.7 35.4 88.1 31.2 28.8 9.6 50.5 113.7 46.1 26.5 28.8 58.2 31.1 73.2 37.5 78.0 8.4 9.9 42.8 42.7 78.2 63.3 12.5 32.3 65.9 56.9 8.4 72.0 76.0 27.8 12.5 24.4 89.8 44.5 47.0 21.6 62.0 65.5 100.0 29.4 8.6 46.0 52.2 53.0 61.3 49.3 61.7 51.3 114.5 21.3 53.3 43.0 86.1 VCAM1 CD106 ENSG00000162692 "Vascular cell adhesion molecule 1" P19320 1 100719742-100739045 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 389.3" "Cell type enhanced" "Detected in many" "Ductal cells: 142.6;Hepatic stellate cells: 94.9;Kupffer cells: 561.9;Proximal tubular cells: 188.4;Theca cells: 186.8" "Cancer enriched" "Detected in all" 8 "renal cancer: 89.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HHSteC: 164.7;HSkMC: 111.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000154, HPA034796, HPA069867" Enhanced Approved "Cell Junctions" NA NA 624000000 1300000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Cell Junctions" "CAB000154: , HPA034796: AB_2674333, HPA069867: AB_2686215" "unprognostic (2.96e-1)" "prognostic favorable (3.82e-4)" "unprognostic (1.31e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" "prognostic favorable (7.19e-5)" "unprognostic (1.60e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (1.20e-1)" "unprognostic (3.95e-2)" "unprognostic (8.23e-2)" "unprognostic (1.80e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.55e-2)" 29.1 43.2 4.0 34.7 3.5 8.3 15.0 5.0 4.5 6.7 6.0 15.0 15.4 9.4 2.4 7.7 9.8 29.5 9.4 2.8 7.6 64.3 43.7 18.1 96.3 6.5 6.2 39.5 13.3 18.4 7.0 43.2 7.0 9.7 23.5 1.5 8.7 5.5 3.1 3.6 14.4 11.0 6.0 389.3 14.4 5.4 11.2 24.6 7.3 6.3 75.9 72.7 5.5 5.9 0.0 0.0 0.8 0.3 0.6 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.1 25.7 0.0 0.0 0.0 0.0 164.7 0.2 0.0 111.0 0.0 29.3 0.2 0.0 1.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.5 5.0 4.5 2.8 7.6 6.5 6.2 7.0 6.0 11.2 5.9 9.6 0.0 5.6 0.0 1.7 9.9 0.5 0.4 0.0 0.1 0.9 0.6 1.9 0.0 0.2 3.7 0.0 1.3 1.1 0.0 9.8 142.6 0.3 0.7 14.0 40.3 0.0 2.7 0.0 3.2 1.2 60.1 0.0 0.8 1.3 7.5 94.9 3.2 3.6 0.0 0.0 0.0 0.0 561.9 15.9 0.0 17.1 7.9 1.8 6.5 0.0 4.0 0.0 0.0 0.1 2.3 1.1 7.5 0.9 1.3 0.0 188.4 1.5 0.0 0.0 5.5 19.2 0.1 2.3 0.4 7.4 2.7 10.0 186.8 0.1 0.4 VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 349.4;Muller glia cells: 265.8" "Cancer enhanced" "Detected in all" "renal cancer: 79.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 398.9;U-87 MG: 628.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" NA NA 562000 57000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "CAB005429: AB_2212984, CAB039240: , CAB069907: AB_10001947, HPA069116: AB_2686089" "unprognostic (1.12e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (2.42e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.34e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (1.76e-5)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.73e-4)" 155.8 52.7 17.6 36.5 20.3 45.5 92.4 34.2 28.2 45.2 46.8 32.6 50.9 104.0 10.5 61.3 40.9 80.1 208.3 22.8 25.1 116.9 217.3 94.1 9.3 27.0 38.5 25.0 68.1 105.0 22.3 46.2 26.8 120.3 21.4 229.1 32.1 17.8 221.2 44.2 44.6 57.1 19.6 70.1 63.9 5.3 32.0 5.6 270.9 150.9 9.5 122.3 61.7 24.9 76.5 13.4 12.5 71.8 21.0 32.9 84.2 45.6 81.1 29.7 58.4 43.1 9.9 24.9 35.5 27.7 305.4 30.6 34.0 92.0 52.0 27.4 10.4 19.0 17.8 29.2 220.3 20.8 40.4 58.0 178.6 290.6 286.2 398.9 7.7 21.0 35.7 121.7 109.4 31.3 2.3 28.3 7.9 221.2 19.2 2.3 12.0 60.5 114.8 62.9 22.3 46.8 65.6 44.4 162.0 16.1 17.3 75.1 10.4 122.6 32.9 179.2 76.1 68.8 43.6 49.1 628.6 47.9 43.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 20.3 34.2 28.2 22.8 25.1 27.0 38.5 26.8 19.6 32.0 24.9 63.6 349.4 84.7 121.5 9.8 70.5 51.2 76.8 60.3 37.8 67.0 57.1 164.7 77.2 85.7 22.0 31.3 1.3 11.6 92.9 1.9 54.7 0.0 38.4 59.1 29.0 27.4 21.3 12.1 40.8 6.3 69.7 124.4 121.2 112.0 111.7 17.5 116.0 13.9 180.0 17.0 71.8 12.2 16.2 199.0 0.3 1.8 144.1 28.4 10.3 11.3 265.8 0.0 124.1 1.8 86.0 47.1 3.4 15.9 119.4 61.9 20.5 11.4 43.9 0.0 42.1 79.1 1.1 1.9 82.0 78.3 7.9 11.4 17.4 51.0 137.5 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.9;Muller glia cells: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 209.8 82.0 45.7 12.0 51.3 3.9 151.3 41.8 53.1 103.6 48.2 151.5 12.1 99.9 7.2 50.8 72.5 19.2 253.3 38.7 45.1 84.6 44.0 82.5 14.4 54.8 47.4 82.6 84.9 18.3 104.2 9.8 45.0 92.7 4.7 12.7 57.7 28.5 143.8 77.3 59.5 10.2 44.2 55.9 89.2 17.5 50.6 6.6 83.7 51.5 9.1 118.0 77.5 37.3 15.4 25.9 9.9 28.1 49.7 36.8 12.7 14.7 27.8 13.1 16.0 13.8 31.7 19.8 28.6 14.0 28.8 20.8 15.8 11.5 2.3 20.6 15.1 16.7 33.9 13.3 45.4 4.8 20.1 39.6 12.0 19.6 12.2 33.9 18.4 20.6 20.2 32.5 22.2 31.8 27.4 12.6 7.0 10.9 22.3 32.1 20.5 46.5 11.0 19.5 14.0 46.4 12.4 38.1 57.4 7.6 25.1 5.6 13.0 50.8 30.2 23.1 8.7 90.5 45.5 15.4 41.6 5.3 25.1 0.3 0.2 0.6 0.9 0.0 0.8 3.0 0.8 0.9 0.4 2.4 0.9 1.6 0.0 0.4 0.0 30.5 0.5 0.4 45.7 51.3 41.8 53.1 38.7 45.1 54.8 47.4 45.0 44.2 50.6 37.3 54.1 19.2 32.6 43.8 27.6 12.7 6.7 10.1 2.2 47.9 32.8 65.7 204.9 10.0 7.6 14.7 33.3 9.6 68.3 11.9 39.2 14.8 1.1 24.2 47.7 21.9 53.3 4.4 7.3 12.9 16.8 68.6 5.1 31.6 18.4 62.7 19.6 9.8 51.4 65.6 26.6 12.2 20.3 31.5 21.5 3.5 60.9 50.0 35.6 19.7 17.7 130.6 12.3 29.1 11.8 14.5 7.3 109.1 12.3 11.5 20.3 31.6 8.9 39.6 6.6 47.4 53.7 0.5 1.2 6.4 13.9 8.9 19.0 34.3 12.8 7.5 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VEGFD "FIGF, VEGF-D" ENSG00000165197 "Vascular endothelial growth factor D" O43915 X 15345596-15384413 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 42.7" "Cell type enriched" "Detected in some" 12 "Fibroblasts: 39.8" "Cancer enhanced" "Detected in some" "liver cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.4;ASC TERT1: 2.8;EFO-21: 1.3;HSkMC: 2.8" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 3.5;hippocampal formation: 3.3;white matter: 2.6" "Not detected" "Not detected" HPA027342 Uncertain "Secreted to blood" NA NA 592000 450000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA027342: AB_1848597" "unprognostic (5.90e-2)" "unprognostic (9.79e-3)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-1)" "unprognostic (6.06e-3)" "unprognostic (5.57e-2)" "unprognostic (2.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.59e-5)" "unprognostic (3.08e-2)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (1.75e-2)" 11.4 9.9 1.8 0.7 1.8 0.0 20.3 1.5 2.3 19.2 1.5 5.0 1.2 3.8 4.9 2.7 4.1 2.8 15.5 1.6 2.0 1.7 1.5 42.7 0.4 1.8 1.7 4.4 0.7 2.7 7.0 0.2 2.0 1.5 2.0 0.3 2.3 1.8 17.6 1.2 4.2 3.3 1.3 2.8 5.8 0.6 2.1 0.3 1.5 23.0 1.3 6.0 8.1 2.0 0.0 0.6 0.5 0.9 3.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.3 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.3 2.8 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.3 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 1.5 2.3 1.6 2.0 1.8 1.7 2.0 1.3 2.1 2.0 3.1 3.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 39.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.3 0.3 1.6 0.0 0.0 VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141778-10153667 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 146.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031631, HPA031632, HPA068954" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: " "prognostic unfavorable (9.02e-5)" "unprognostic (1.10e-1)" "unprognostic (4.46e-3)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.55e-1)" "unprognostic (3.03e-2)" "unprognostic (4.36e-2)" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (2.51e-1)" "prognostic favorable (7.84e-4)" "unprognostic (1.46e-1)" "unprognostic (2.92e-2)" "unprognostic (1.28e-3)" 14.0 13.7 11.5 21.1 11.0 27.9 14.7 13.6 12.1 11.8 6.7 14.8 15.7 14.1 9.8 12.3 13.4 11.5 7.9 11.8 14.9 12.6 14.1 11.8 29.6 9.4 9.4 12.6 12.7 11.7 9.0 14.1 9.3 14.0 15.7 8.9 14.5 10.2 11.4 14.2 17.2 12.8 9.6 22.5 16.0 13.4 16.6 23.4 15.8 7.7 29.7 12.5 10.9 12.5 19.5 18.2 39.9 24.6 36.0 27.7 146.5 16.8 24.0 21.1 24.5 21.5 23.7 67.9 22.2 23.0 29.9 16.4 37.2 23.6 25.7 33.0 33.7 52.7 30.5 30.6 34.3 47.3 41.3 28.1 26.3 28.0 35.1 28.4 24.6 42.5 48.3 50.3 21.1 35.0 45.5 40.9 26.7 21.1 23.4 57.3 34.6 34.6 25.5 48.7 15.0 49.4 35.0 18.7 21.0 23.9 37.0 59.1 21.3 20.8 27.7 19.6 26.8 35.7 78.1 105.6 23.2 55.3 19.4 4.6 3.2 2.3 2.6 2.2 1.9 2.5 1.8 2.2 2.0 3.3 1.7 1.8 5.6 3.0 2.0 2.3 1.7 1.2 11.5 11.0 13.6 12.1 11.8 14.9 9.4 9.4 9.3 9.6 16.6 12.5 12.4 12.8 12.5 9.1 38.7 14.7 17.8 14.3 24.5 14.7 10.7 6.1 6.1 20.0 9.6 16.5 18.8 16.8 21.9 10.7 7.9 11.8 9.6 13.1 26.1 14.8 14.4 30.5 15.9 5.1 18.7 12.8 20.9 19.9 5.1 18.4 18.9 14.3 14.9 18.5 14.2 11.3 16.2 27.1 45.8 7.3 14.0 32.3 12.4 7.5 31.9 9.1 28.8 12.1 14.9 10.7 11.7 11.3 33.3 23.8 12.3 9.5 9.7 15.3 6.6 17.4 11.9 15.4 24.0 26.7 20.5 17.2 23.5 21.4 10.2 25.9 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 436.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.8;Enteroendocrine cells: 113.6;Intestinal goblet cells: 143.6;Paneth cells: 216.2;Proximal enterocytes: 558.5;Undifferentiated cells: 161.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in some" 97 "CACO-2: 762.5;Hep G2: 365.3;OE19: 321.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" 0.6 1.1 0.0 10.3 0.1 0.3 0.8 0.3 0.2 0.7 0.0 175.9 395.0 0.5 0.0 0.9 0.7 28.1 1.0 0.0 0.0 25.9 31.4 0.7 0.3 0.0 0.0 1.1 29.4 0.0 1.4 0.3 0.0 1.0 184.0 0.0 0.6 0.4 0.4 1.1 436.3 8.1 0.0 1.2 6.9 2.0 0.0 0.0 0.6 0.0 0.0 0.8 0.9 0.1 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 762.5 0.5 0.1 5.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.3 365.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.1 0.0 1.7 0.8 321.9 0.0 0.0 0.0 1.4 0.0 0.2 0.3 0.7 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.3 0.8 0.4 0.1 0.0 1.8 0.3 0.6 0.5 24.3 0.1 0.0 2.1 0.3 0.8 243.8 3.9 12.3 1.9 1.3 0.9 0.4 113.6 3.2 0.7 42.9 0.2 0.8 6.6 1.6 8.9 0.3 0.7 32.6 0.1 1.7 0.5 143.6 0.0 2.2 1.5 0.5 0.0 5.1 0.0 0.0 0.2 0.5 0.0 0.0 0.3 10.9 216.2 0.0 0.3 0.9 558.5 35.1 0.0 1.2 0.0 1.7 0.7 0.8 0.8 0.6 0.9 0.3 1.5 0.0 161.8 0.3 VIP ENSG00000146469 "Vasoactive intestinal peptide" P01282 6 152750797-152759765 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.2;lymphoid tissue: 155.5" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 80.6;Melanocytes: 28.4" "Group enriched" "Detected in some" 6 "colorectal cancer: 3.7;pancreatic cancer: 4.3;stomach cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 2.7;TIME: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017324, CAB018649, HPA072701, CAB079780" Supported Supported Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 122000 "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB018649: AB_2304501, CAB079780: , HPA017324: AB_1858754, HPA072701: AB_2686550" "unprognostic (9.58e-2)" "unprognostic (2.29e-2)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (3.62e-1)" "unprognostic (2.92e-3)" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (5.90e-2)" 2.7 12.2 5.5 155.5 7.9 0.1 1.9 4.9 10.9 1.8 4.6 72.2 16.6 1.2 0.4 4.3 1.5 3.7 4.3 7.3 28.7 2.5 1.1 3.4 0.4 6.9 40.0 0.8 8.3 0.3 0.8 0.6 7.7 2.7 61.4 1.0 0.5 0.5 1.4 0.4 45.8 41.6 4.8 9.7 22.2 1.0 11.9 0.1 2.3 1.7 0.1 1.6 9.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 7.9 4.9 10.9 7.3 28.7 6.9 40.0 7.7 4.8 11.9 5.9 2.5 0.0 0.0 3.3 0.2 0.4 0.0 0.0 0.0 1.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 80.6 0.0 0.0 0.3 0.0 6.5 0.0 0.0 28.4 4.7 0.0 0.0 0.0 2.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 6039.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 5507.4" "Cancer enriched" "Detected in many" 85 "liver cancer: 2216.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "CACO-2: 1748.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 606000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Vesicles" "CAB016695: AB_1624536, CAB016765: , HPA060933: AB_2684389, HPA068011: " "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.13e-2)" "unprognostic (9.74e-2)" "unprognostic (8.42e-2)" "prognostic favorable (3.74e-4)" "unprognostic (6.20e-2)" "unprognostic (3.97e-1)" "unprognostic (8.95e-2)" "unprognostic (3.24e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.10e-11)" "unprognostic (8.82e-3)" "unprognostic (2.27e-1)" "unprognostic (4.86e-3)" "unprognostic (7.09e-2)" 6.2 98.9 2.4 2.5 2.7 0.3 0.9 5.4 3.7 1.0 0.4 0.9 4.6 1.4 0.9 0.5 2.2 61.2 53.1 2.5 2.8 3.6 6039.5 1.8 4.3 2.1 5.3 1.9 17.7 0.1 3.0 40.6 2.3 1.2 0.3 47.4 0.6 4.3 0.4 0.8 1.3 2.7 1.5 2.9 5.1 10.0 2.2 0.1 0.8 0.5 0.4 4.2 0.7 2.4 0.0 28.4 0.7 0.4 0.2 0.3 7.3 1.8 0.8 0.9 0.9 1748.9 0.1 1.2 0.2 0.2 0.2 0.7 0.0 0.0 0.1 0.2 0.2 1.2 1.1 86.7 2.5 6.1 0.5 0.4 0.0 0.6 0.0 3.9 0.1 0.0 1.6 0.3 0.2 0.7 0.2 0.0 0.8 0.4 0.1 0.4 3.5 0.1 0.3 0.0 1.0 1.4 115.6 8.0 0.2 4.3 0.3 0.0 1.0 0.4 0.3 0.1 0.2 1.0 0.5 1.4 0.5 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 2.4 2.7 5.4 3.7 2.5 2.8 2.1 5.3 2.3 1.5 2.2 2.4 0.1 0.0 1.1 2.0 21.5 0.0 0.0 0.0 0.0 13.0 0.1 0.1 18.1 1162.4 0.0 0.0 77.2 3.7 0.0 0.0 3.9 16.8 0.0 0.0 1.2 7.3 0.0 131.0 0.9 19.7 2.8 48.1 0.0 0.0 0.0 1.8 120.3 5507.4 4.7 38.7 1.0 0.1 0.0 160.3 0.3 0.2 0.0 0.3 0.0 0.0 20.1 6.9 0.0 1.0 0.5 23.5 1.2 1.5 0.0 0.0 0.1 9.5 0.0 38.3 0.0 0.4 1.5 4.2 0.6 0.0 0.0 9.6 9.0 0.7 0.0 0.0 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Cell line enhanced" "Detected in some" "Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 10.2 5.2 6.3 52.2 5.8 58.4 4.4 5.9 8.1 3.3 6.3 6.4 8.0 2.8 3.0 3.5 5.6 6.9 3.5 6.0 8.0 4.4 7.2 19.1 54.2 11.1 8.2 1.8 2.4 1.4 2.9 9.0 8.6 4.2 5.0 0.4 4.9 2.8 1.4 2.8 23.0 6.1 8.0 83.0 7.0 1.9 8.6 42.0 3.5 3.4 36.2 10.3 3.0 10.8 0.8 0.2 0.4 1.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.9 76.5 0.3 0.0 0.3 2.0 0.3 0.2 0.0 44.2 0.4 67.6 0.9 0.0 0.8 34.9 157.0 0.3 0.1 0.1 0.0 0.0 0.0 40.3 0.7 45.7 0.0 7.6 70.8 75.7 0.4 1.1 0.4 61.1 0.3 94.0 0.1 0.0 0.5 0.9 1.0 0.7 0.5 0.2 0.4 68.8 0.5 0.1 0.4 1.2 0.1 83.1 43.6 53.7 0.5 87.4 0.2 3.3 7.6 37.4 4.6 8.4 3.4 3.0 3.5 3.9 5.7 3.3 3.1 3.5 29.2 3.6 9.5 3.1 5.4 4.0 6.3 5.8 5.9 8.1 6.0 8.0 11.1 8.2 8.6 8.0 8.6 10.8 1.5 3.2 14.3 0.7 83.2 2.4 0.2 0.2 2.2 0.2 1.1 1.8 1.1 0.0 0.1 0.0 0.0 0.9 91.7 0.3 1.9 0.4 0.6 0.4 0.4 2.6 1.2 14.1 0.3 0.4 1.1 1.5 5.6 0.3 48.1 0.2 3.9 1.6 111.5 0.0 0.3 0.2 0.0 110.7 54.5 1.1 0.0 118.1 3.6 4.7 88.2 0.2 84.5 0.5 0.0 0.1 0.1 0.0 57.8 0.2 0.1 1.8 1.6 0.2 0.0 1.0 1.3 1.3 1.1 0.8 1.4 1.4 99.3 0.4 0.1 0.2 WASF3 "KIAA0900, SCAR3, WAVE3" ENSG00000132970 "WASP family member 3" Q9UPY6 13 26557683-26688948 "Cancer-related genes, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.0;retina: 56.4" "Cell type enhanced" "Detected in many" "Astrocytes: 161.6;Early spermatids: 104.1;Horizontal cells: 82.4;Inhibitory neurons: 127.5;Oligodendrocyte precursor cells: 69.9" "Cancer enhanced" "Detected in all" "glioma: 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037086, HPA066228" Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "CAB037086: AB_1080585, HPA066228: " "unprognostic (1.42e-1)" "unprognostic (3.65e-2)" "unprognostic (2.25e-1)" "unprognostic (7.57e-2)" "unprognostic (8.23e-2)" "unprognostic (3.34e-1)" "unprognostic (6.19e-2)" "unprognostic (8.37e-2)" "unprognostic (8.98e-2)" "unprognostic (2.99e-1)" "prognostic favorable (2.21e-4)" "unprognostic (8.86e-3)" "unprognostic (2.93e-3)" "unprognostic (6.35e-2)" "unprognostic (2.12e-2)" "unprognostic (2.69e-3)" "unprognostic (9.18e-2)" 19.6 15.9 49.6 2.8 52.4 0.3 14.7 60.0 50.0 9.3 2.6 7.4 1.0 9.1 4.9 3.9 11.2 4.0 8.7 48.9 48.1 6.9 6.9 7.4 2.6 40.2 51.1 20.9 5.2 6.7 8.6 0.5 31.3 9.0 3.1 56.4 6.1 9.3 7.8 4.7 3.8 7.6 28.8 5.1 7.2 13.0 50.3 1.6 17.0 5.0 1.7 7.4 7.6 45.2 0.0 0.2 39.4 0.1 82.8 16.4 3.6 17.6 24.7 26.4 11.7 0.0 3.7 15.3 2.1 39.5 10.2 3.6 10.7 11.4 20.7 0.0 9.9 1.0 0.0 15.0 12.3 5.8 11.2 33.7 10.7 5.6 17.1 5.4 35.2 5.0 0.5 0.1 8.3 3.2 0.0 0.2 10.5 0.6 3.8 0.0 21.5 0.1 2.9 7.3 9.2 18.9 8.6 7.4 11.5 8.4 0.0 0.6 20.1 19.3 7.4 10.1 9.1 0.0 0.0 15.1 9.3 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 52.4 60.0 50.0 48.9 48.1 40.2 51.1 31.3 28.8 50.3 45.2 11.2 25.6 2.0 161.6 0.2 2.2 2.8 1.7 2.8 46.2 4.9 6.5 9.8 4.3 1.9 9.2 33.3 0.1 0.3 0.9 11.7 2.3 104.1 1.3 4.6 8.3 20.4 0.0 49.4 2.7 0.3 15.7 2.0 2.3 14.7 62.8 12.5 8.2 0.3 82.4 127.5 1.3 0.0 1.9 2.7 35.3 14.6 4.3 5.4 30.9 0.7 46.7 1.0 69.9 41.0 2.0 0.0 29.0 0.1 5.1 0.0 3.3 1.2 41.2 6.6 32.0 9.1 7.2 18.7 2.0 1.4 0.0 0.2 5.1 0.5 1.9 WDCP "C2orf44, FLJ21945, MMAP" ENSG00000163026 "WD repeat and coiled coil containing" Q9H6R7 2 24029347-24049575 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 9.2;Distal tubular cells: 7.9;Granulosa cells: 4.3;Theca cells: 4.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041054 Approved Approved Nucleoli,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoli Cytosol "HPA041054: AB_10796566" "unprognostic (1.07e-1)" "unprognostic (3.19e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (5.14e-8)" "unprognostic (7.69e-2)" "unprognostic (9.01e-3)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (5.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (7.76e-2)" "unprognostic (3.00e-1)" 2.6 3.7 3.9 3.8 4.1 1.4 4.4 4.7 4.0 3.5 4.6 4.2 2.5 4.2 3.7 3.2 3.2 2.7 3.4 3.8 4.0 3.5 4.1 2.6 6.6 3.9 4.1 5.4 2.6 5.0 2.3 4.2 4.0 3.6 2.9 6.3 2.9 4.5 6.1 2.9 3.3 3.5 3.9 4.2 3.0 4.9 4.3 7.7 3.1 8.7 7.0 3.6 2.7 4.6 12.3 18.8 20.1 14.0 13.6 10.7 7.2 14.6 7.8 15.1 14.1 17.2 5.6 32.0 6.2 7.5 12.6 8.8 28.7 10.0 15.6 19.4 16.4 19.7 8.5 17.8 9.3 18.0 13.0 6.5 7.6 15.6 7.7 7.8 14.3 18.4 27.5 8.7 15.9 5.6 23.8 10.8 24.3 12.2 14.3 25.7 33.8 12.9 7.1 6.1 15.4 21.3 7.2 7.0 9.1 14.0 5.4 7.9 13.9 12.0 13.1 7.2 13.6 14.4 19.2 45.2 7.7 19.0 9.5 0.0 1.8 1.1 5.2 2.7 5.3 3.3 3.3 3.8 3.1 2.9 4.6 5.0 0.4 3.9 2.0 1.1 5.4 3.3 3.9 4.1 4.7 4.0 3.8 4.0 3.9 4.1 4.0 3.9 4.3 4.6 3.1 3.2 3.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 9.2 0.0 2.9 1.8 0.0 7.9 2.3 0.0 1.5 3.2 1.6 0.0 0.0 0.0 2.0 2.5 1.4 0.0 1.0 0.0 4.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.1 1.0 4.5 0.0 0.0 WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573670-9593457 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 213.9;Glandular and luminal cells: 262.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB004619, HPA068845" Approved Approved Nucleoli No No "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoli "CAB004619: AB_628447, HPA068845: AB_2686048" "unprognostic (6.04e-2)" "unprognostic (1.90e-3)" "unprognostic (1.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-2)" "unprognostic (3.79e-3)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-2)" "unprognostic (3.21e-3)" "unprognostic (3.73e-1)" "prognostic unfavorable (5.19e-4)" "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (2.08e-1)" "unprognostic (3.80e-1)" 12.7 5.6 1.5 14.1 1.3 23.0 46.1 2.4 2.3 21.5 2.8 18.4 10.6 62.6 24.5 46.3 18.6 49.0 43.0 1.2 2.3 16.8 57.8 11.6 24.8 2.8 4.0 10.9 10.1 17.8 8.4 34.6 3.6 21.2 14.4 4.5 17.4 12.7 10.4 57.1 13.5 35.0 2.2 8.1 17.2 31.5 2.0 23.7 26.6 7.2 30.2 53.0 15.4 1.9 43.1 16.4 69.1 38.8 65.2 29.8 125.9 48.8 44.8 29.3 29.8 33.8 53.3 100.7 18.0 27.6 30.8 48.8 49.0 23.3 41.1 33.3 30.7 43.1 30.1 26.2 7.0 66.6 39.7 12.0 25.3 13.8 53.8 34.9 21.6 43.6 64.0 75.8 55.7 13.2 63.5 39.4 97.6 36.9 18.5 57.6 54.5 24.6 28.1 100.0 25.0 31.8 39.9 48.6 29.2 89.3 27.1 32.9 21.7 51.1 35.2 23.0 42.2 14.4 51.1 140.1 23.3 36.5 41.0 0.0 0.0 6.0 1.7 0.0 0.2 8.0 1.7 3.0 0.1 4.7 0.1 1.3 0.1 1.9 0.0 0.1 7.1 0.6 1.5 1.3 2.4 2.3 1.2 2.3 2.8 4.0 3.6 2.2 2.0 1.9 17.2 51.3 33.9 0.0 36.8 176.4 170.4 38.5 213.9 1.8 168.5 67.2 61.1 65.8 53.5 42.3 0.0 94.8 11.2 54.7 13.7 24.9 25.0 160.1 86.2 18.7 61.1 40.4 0.1 13.6 200.1 39.2 52.5 262.4 7.0 28.5 9.7 85.0 17.0 1.7 0.4 65.6 18.3 2.5 21.9 41.7 11.8 10.0 17.8 1.0 2.4 9.9 8.2 2.0 0.1 24.8 38.5 10.9 17.2 82.7 35.9 8.3 62.6 7.1 6.6 180.7 23.7 61.4 44.4 181.4 191.1 137.2 19.0 11.8 55.5 85.5 WFDC2 "dJ461P17.6, EDDM4, HE4, WAP5" ENSG00000101443 "WAP four-disulfide core domain 2" Q14508 20 45469753-45481532 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartic protease inhibitor, Protease inhibitor, Serine protease inhibitor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 5211.9;salivary gland: 1988.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4507.8;Club cells: 6299.8;Collecting duct cells: 1988.1;Endometrial ciliated cells: 3253.3;Glandular and luminal cells: 4817.5;Respiratory ciliated cells: 2935.3;Urothelial cells: 3783.3" "Group enriched" "Detected in all" 4 "endometrial cancer: 1815.6;ovarian cancer: 1086.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "A-431: 115.8;CAPAN-2: 210.6;EFO-21: 171.3;HaCaT: 151.9;RPTEC TERT1: 165.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042302 Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA042302: AB_2677939" "unprognostic (5.75e-2)" "unprognostic (2.23e-1)" "unprognostic (4.37e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (7.19e-3)" "unprognostic (1.94e-1)" "unprognostic (5.49e-3)" "unprognostic (3.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.42e-1)" "unprognostic (1.40e-1)" "prognostic favorable (4.44e-5)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" "unprognostic (3.20e-2)" 16.8 1.6 6.7 11.0 14.1 0.0 81.2 6.6 9.3 5211.9 22.3 163.7 9.6 240.0 941.9 54.9 676.7 166.1 6.0 7.2 7.5 909.9 23.6 144.7 0.9 7.7 9.1 10.4 30.5 81.9 152.4 0.7 7.1 221.7 224.9 6.9 1988.3 825.3 2.0 38.2 60.1 28.9 6.9 0.7 44.1 14.9 7.2 12.3 253.8 0.5 8.8 161.2 25.0 7.3 115.8 0.0 0.3 0.4 0.0 0.1 4.7 0.0 0.0 0.0 0.0 4.9 210.6 0.0 171.3 0.0 0.7 151.9 0.0 0.0 0.0 0.8 1.9 0.0 1.2 0.3 0.0 0.2 0.7 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 6.7 0.3 2.7 18.4 0.6 0.0 0.1 0.0 0.0 165.6 1.3 5.0 1.0 10.6 0.0 1.1 2.0 3.1 0.6 0.0 0.3 2.8 0.6 0.5 0.7 0.6 1.6 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.7 14.1 6.6 9.3 7.2 7.5 7.7 9.1 7.1 6.9 7.2 7.3 2.8 169.9 273.8 2.6 4.2 8.9 1190.9 4507.8 35.3 30.3 340.4 238.5 2.0 94.4 6299.8 1988.1 22.9 1.0 4.3 239.8 221.1 308.2 1.6 3253.3 359.3 21.7 422.7 0.0 4.7 129.2 0.8 23.4 31.6 4817.5 10.1 12.5 3.9 3.3 1.9 0.0 7.6 1764.7 1328.5 0.6 1.1 5.0 36.1 26.8 10.6 1.9 5.7 31.3 0.0 2.0 3.4 179.0 424.6 0.0 0.8 1169.7 1.7 113.9 2935.3 6.1 6.6 1.1 319.1 12.4 11.9 110.2 14.1 0.7 36.8 0.0 318.2 3783.3 WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2736.1" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.2;LHCN-M2: 1.0;NTERA-2: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" 1.3 2.7 22.4 0.3 34.3 0.0 22.9 16.3 44.6 1.6 15.0 0.3 0.0 8.6 23.8 4.7 1.5 0.0 0.5 24.8 35.4 0.7 0.0 117.4 0.1 16.6 16.5 1.2 0.3 0.0 46.5 0.0 16.2 14.2 0.3 599.7 45.1 2.8 0.1 6.6 2.2 0.9 16.5 0.1 1.4 0.7 23.4 0.2 0.0 0.7 0.0 1.7 2.2 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 34.3 16.3 44.6 24.8 35.4 16.6 16.5 16.2 16.5 23.4 18.4 0.0 35.3 197.8 186.1 0.0 12.6 34.5 0.0 2.2 25.0 0.7 13.7 1.6 0.0 26.6 1.8 8.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 4.7 0.0 0.0 0.6 0.0 0.0 27.8 0.5 0.1 7.6 1.0 0.0 0.0 0.0 15.2 46.5 0.0 0.0 0.0 20.4 0.0 0.0 0.8 23.2 12.2 0.0 2736.1 0.0 1.5 0.9 0.0 0.0 0.4 0.2 25.5 0.0 1.2 34.2 80.8 0.0 1.8 1.5 2.5 2.0 0.4 10.5 0.0 1.2 0.0 0.0 0.8 WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 4.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.1;Gastric mucus-secreting cells: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 4.5;cerebral cortex: 2.1" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 29 "T-cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" "Secreted to extracellular matrix" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" 0.0 0.0 0.8 0.5 4.5 1.1 0.0 0.0 2.1 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.1 0.7 0.2 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.3 0.7 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 5.1 0.1 2.0 2.9 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.2 0.5 0.8 4.5 0.0 2.1 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 39.9" "Cell type enhanced" "Detected in some" "Early spermatids: 30.9;Endometrial stromal cells: 33.1;Fibroblasts: 82.5;Late spermatids: 14.7;Spermatocytes: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 11.5" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA020920: AB_1858850" "unprognostic (1.90e-1)" "unprognostic (6.97e-2)" "unprognostic (2.88e-2)" "unprognostic (4.11e-3)" "unprognostic (9.14e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-2)" "unprognostic (2.75e-1)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.36e-2)" "unprognostic (1.41e-1)" "unprognostic (3.43e-1)" "unprognostic (4.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-1)" 1.2 0.0 0.2 0.1 0.4 0.0 0.8 0.1 0.7 3.5 0.3 0.1 0.0 8.6 0.1 0.0 0.8 0.2 0.4 0.4 0.3 0.1 0.5 6.9 0.0 0.1 0.5 0.3 0.1 0.0 0.1 39.9 0.1 3.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.1 0.1 0.9 0.0 0.5 1.5 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.7 0.4 0.3 0.1 0.5 0.1 0.1 1.5 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 1.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 30.9 0.8 33.1 9.8 0.0 0.0 1.4 0.0 3.6 82.5 0.0 0.6 0.0 0.0 10.8 0.6 7.7 0.0 0.5 0.0 0.0 0.8 0.3 14.7 1.5 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 13.6 0.5 0.0 2.7 9.0 0.2 0.0 0.0 0.2 WRN "RECQ3, RECQL2" ENSG00000165392 "WRN RecQ like helicase" Q14191 8 31033788-31176138 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 74.7;Early spermatids: 116.3;Oligodendrocytes: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 3.0 3.6 1.7 3.2 1.7 8.2 4.8 4.1 2.4 3.0 2.6 3.5 1.5 6.4 3.2 2.7 2.9 2.4 1.7 1.6 1.7 2.1 2.5 2.4 2.5 1.8 2.1 5.2 2.6 2.0 2.1 3.6 1.8 3.5 2.9 4.4 3.5 2.6 2.1 4.1 2.5 4.2 1.2 3.1 2.3 3.0 1.9 3.2 3.2 2.2 3.0 2.6 2.3 3.1 4.4 5.9 10.8 5.3 6.7 9.8 5.0 4.7 4.9 6.4 6.6 2.7 1.5 10.0 4.6 4.3 4.4 2.4 6.4 3.8 9.7 3.3 4.3 9.6 4.9 4.4 5.4 8.7 4.3 7.1 3.7 3.6 6.2 3.9 7.7 6.1 14.5 5.0 6.8 2.0 17.5 6.6 7.7 5.1 3.2 7.5 7.5 6.7 2.9 4.4 3.3 5.2 6.9 2.7 3.8 4.9 2.9 5.3 9.1 6.2 3.8 3.1 4.9 1.4 3.0 14.6 5.5 3.8 4.2 0.8 0.2 0.3 0.3 0.1 0.4 0.5 0.5 0.3 0.2 0.5 0.3 0.4 0.3 1.1 0.1 0.1 0.3 0.1 1.7 1.7 4.1 2.4 1.6 1.7 1.8 2.1 1.8 1.2 1.9 3.1 17.5 9.6 10.6 74.7 15.1 13.5 11.7 5.3 18.8 14.5 14.7 10.5 7.5 15.7 8.8 16.5 22.9 7.1 18.0 5.3 1.9 6.7 116.3 15.8 32.3 12.5 2.4 49.2 59.7 9.8 5.7 15.2 21.9 17.1 2.5 18.5 7.1 9.7 5.3 15.2 54.9 13.8 8.2 5.3 6.6 12.8 19.0 7.8 10.6 51.5 6.9 14.3 4.1 61.3 88.6 9.1 4.2 14.3 16.6 15.3 3.9 2.7 10.0 19.8 6.6 20.2 15.3 10.9 19.2 10.1 10.2 5.6 13.0 15.2 7.7 11.0 WT1 "AWT1, GUD, NPHS4, WAGR, WIT-2" ENSG00000184937 "WT1 transcription factor" P19544 11 32387775-32435564 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8" "Cell type enhanced" "Detected in some" "Collecting duct cells: 20.2;Endometrial stromal cells: 70.1;Endothelial cells: 16.3;Granulosa cells: 9.3;Late spermatids: 9.3" "Cancer enriched" "Detected in many" 14 "ovarian cancer: 55.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 20.7;HMC-1: 29.9;K-562: 19.6;NB-4: 37.2;THP-1: 19.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000327, HPA035717, HPA053848" Enhanced Enhanced Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279" "unprognostic (3.09e-3)" "unprognostic (9.97e-4)" "unprognostic (3.32e-1)" "unprognostic (8.24e-3)" "unprognostic (5.20e-2)" "unprognostic (1.98e-3)" "unprognostic (2.94e-2)" "unprognostic (1.59e-2)" "unprognostic (1.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" "unprognostic (1.31e-10)" "unprognostic (2.65e-3)" "unprognostic (1.87e-1)" "unprognostic (1.96e-3)" "unprognostic (1.30e-2)" 26.5 0.2 0.0 0.5 0.1 0.0 0.1 0.0 0.1 18.4 0.0 0.7 0.0 67.6 5.3 0.0 52.3 1.3 4.5 0.1 0.0 16.3 0.1 0.8 0.0 0.2 0.1 45.8 0.1 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 33.1 0.0 19.0 0.2 24.2 0.0 0.0 0.0 0.0 0.0 0.2 8.4 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 8.4 20.7 0.0 1.2 4.7 10.8 29.9 0.0 0.0 3.4 0.0 0.0 0.0 0.7 19.6 0.0 2.0 0.0 11.2 37.2 0.8 0.0 6.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 2.1 19.6 0.2 0.0 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 20.2 0.0 1.0 0.0 0.0 0.0 0.0 3.6 2.2 70.1 16.3 0.0 0.0 0.1 0.0 0.5 7.3 0.0 1.4 0.0 9.3 1.4 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 9.3 8.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.1 0.0 2.3 0.0 0.0 6.6 0.0 2.0 4.5 1.0 0.0 0.0 0.8 0.5 0.4 0.0 0.1 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1159.0" "Cell type enhanced" "Detected in all" "Breast glandular cells: 1756.7;Plasma cells: 2344.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 960.5;SK-BR-3: 870.0;T-47d: 1012.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" 100.3 103.7 23.8 150.1 25.9 247.2 720.6 26.8 27.7 369.7 46.8 203.6 163.7 94.2 150.5 85.2 126.5 120.2 75.8 22.5 32.2 87.7 687.3 151.8 138.3 33.3 33.2 67.5 1159.0 195.1 87.7 107.9 29.0 228.8 196.5 21.1 849.4 152.1 90.1 72.2 140.3 105.5 30.8 213.2 259.9 22.2 33.0 148.2 168.9 48.7 307.8 250.4 52.2 30.8 77.1 50.8 71.4 111.0 132.2 144.2 181.1 130.9 223.2 128.4 168.8 82.5 104.4 290.2 63.0 121.8 75.3 104.5 134.2 64.4 110.4 130.0 84.9 88.3 42.6 356.2 285.9 166.1 80.8 90.7 378.2 85.2 363.7 115.9 104.1 35.0 79.5 355.0 78.6 960.5 23.3 157.0 49.7 594.6 79.0 168.6 78.5 401.5 118.4 105.4 94.7 90.7 79.0 870.0 358.6 94.8 1012.9 188.5 59.8 73.3 69.8 78.5 47.3 598.8 456.8 174.8 98.0 210.0 112.3 185.0 27.1 23.5 73.3 14.1 95.2 38.0 52.4 76.5 23.5 43.8 52.9 43.2 2.1 88.5 10.1 75.0 20.5 38.5 23.8 25.9 26.8 27.7 22.5 32.2 33.3 33.2 29.0 30.8 33.0 30.8 116.4 86.6 195.6 3.6 379.0 210.6 410.2 192.2 47.3 25.4 1756.7 829.4 46.2 205.9 390.1 138.0 131.3 112.8 298.6 171.2 80.3 240.6 30.2 160.1 147.8 107.0 189.7 68.6 8.5 633.3 335.4 220.0 208.0 293.6 99.7 55.1 93.1 654.5 267.9 15.2 11.4 633.0 225.9 130.0 281.5 22.7 95.7 172.3 355.8 18.7 95.0 18.6 385.2 8.0 7.3 328.4 190.5 64.7 2344.9 381.9 247.0 73.2 168.9 53.2 13.1 144.4 179.3 36.8 32.5 86.2 202.0 349.7 206.1 34.8 260.0 355.3 XIAP "API3, BIRC4, hILP, ILP-1" ENSG00000101966 "X-linked inhibitor of apoptosis" P98170 X 123859724-123913976 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway, Wnt signaling pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009203, HPA042428" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009203: AB_2257167, HPA042428: AB_2677993" "prognostic unfavorable (9.21e-4)" "unprognostic (8.43e-2)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (9.41e-2)" "unprognostic (1.95e-2)" "unprognostic (8.51e-2)" "unprognostic (9.17e-2)" "unprognostic (3.90e-2)" "unprognostic (7.50e-2)" "unprognostic (4.41e-2)" "unprognostic (3.15e-3)" "unprognostic (8.21e-3)" "unprognostic (2.26e-1)" "unprognostic (4.99e-2)" "unprognostic (4.65e-2)" 9.2 7.7 6.5 9.2 7.5 8.3 9.7 6.8 7.0 9.6 12.9 12.4 10.1 8.4 10.0 11.5 7.4 8.6 7.8 5.8 8.2 11.8 12.1 8.5 10.4 7.6 8.1 7.5 8.3 18.4 6.3 8.6 7.3 8.5 10.1 21.4 8.6 7.4 10.3 8.8 10.1 7.4 8.5 10.4 10.2 4.2 8.1 8.9 14.9 11.9 8.6 9.6 6.1 10.3 15.8 13.2 10.2 8.8 11.8 15.0 13.3 16.9 12.4 8.9 7.7 5.9 17.9 14.7 24.3 14.4 17.1 5.6 15.3 10.5 16.3 15.5 8.3 9.9 11.1 9.2 14.9 18.1 19.7 10.4 16.0 14.9 19.0 10.2 12.7 10.8 15.9 16.4 17.6 16.5 10.2 8.8 8.4 15.6 10.3 10.8 11.9 15.6 13.4 22.6 6.8 10.0 22.9 13.0 13.5 9.0 8.0 8.7 15.7 0.5 6.0 27.0 18.9 13.8 14.9 15.8 18.3 12.7 11.5 9.3 1.8 2.6 3.3 1.5 3.0 3.1 2.4 3.6 1.0 4.0 2.7 1.9 5.6 2.4 2.9 2.9 1.8 1.5 6.5 7.5 6.8 7.0 5.8 8.2 7.6 8.1 7.3 8.5 8.1 10.3 50.0 80.1 91.6 26.4 42.1 26.6 36.3 35.0 28.5 72.1 29.7 19.9 44.5 44.3 55.2 53.3 95.9 17.9 41.7 122.9 27.4 36.0 2.7 38.4 44.9 55.0 47.4 23.5 30.0 54.0 30.0 38.4 39.8 50.4 60.7 30.9 64.2 85.8 29.0 75.7 34.9 62.2 26.4 43.6 33.0 4.1 42.6 44.2 8.8 29.0 45.8 45.8 55.6 32.6 41.9 65.4 53.5 51.6 39.5 53.0 59.2 59.8 50.6 133.7 65.7 43.6 34.9 15.2 21.0 30.8 35.5 38.0 40.8 30.0 48.0 68.1 XIRP2 CMYA3 ENSG00000163092 "Xin actin binding repeat containing 2" A4UGR9 2 166888480-167259753 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 202.3;skeletal muscle: 1034.1;tongue: 543.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 1907.2" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;HUVEC TERT2: 4.2;U-2197: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034813, HPA074599" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA034813: AB_10602588, HPA074599: " "unprognostic (5.27e-4)" "unprognostic (5.96e-3)" "unprognostic (7.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (2.56e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 202.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.9 0.0 0.0 8.0 0.0 1034.1 1.2 0.1 0.0 0.0 0.5 0.1 3.0 0.0 0.1 0.3 543.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1907.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 10.1 0.0 0.0 1.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 23.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.4 5.8 1.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 XPA "XP1, XPAC" ENSG00000136936 "XPA, DNA damage recognition and repair factor" P23025 9 97674909-97697340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000155, HPA056856" Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Cytokinetic bridge" "CAB000155: , HPA056856: AB_2683258" "unprognostic (8.76e-2)" "unprognostic (1.05e-3)" "unprognostic (1.60e-1)" "unprognostic (2.30e-2)" "unprognostic (4.17e-1)" "unprognostic (1.84e-1)" "unprognostic (5.26e-2)" "unprognostic (2.38e-1)" "unprognostic (3.90e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-3)" "unprognostic (9.55e-3)" "prognostic favorable (4.28e-5)" "unprognostic (2.19e-2)" "unprognostic (1.56e-1)" "unprognostic (3.03e-2)" "unprognostic (1.17e-1)" 15.1 13.4 9.9 9.5 10.3 9.1 13.4 12.0 15.4 13.9 10.8 23.0 15.8 14.0 11.0 14.9 13.1 9.7 9.9 9.7 10.8 18.4 18.8 11.3 14.0 10.2 10.0 13.0 11.8 18.7 9.9 9.7 9.8 14.8 9.9 10.6 12.5 12.7 19.5 12.5 13.1 12.0 9.7 12.5 21.6 5.2 10.7 11.0 23.6 8.6 17.2 15.4 13.5 10.6 35.5 8.2 11.9 14.8 14.3 13.7 8.2 9.4 14.9 16.9 11.4 21.4 28.9 19.9 8.9 10.5 11.3 17.4 9.6 11.4 14.1 13.7 19.2 15.7 17.7 12.0 15.5 18.7 18.2 12.0 12.0 7.9 8.0 11.4 19.1 16.1 22.0 15.2 9.4 11.0 24.4 22.5 8.2 33.5 13.5 24.6 25.4 17.0 27.0 13.7 16.7 16.7 13.4 10.3 12.7 9.0 14.9 11.1 12.0 5.9 14.8 23.4 20.6 26.5 22.7 12.3 14.6 13.2 11.8 12.8 21.6 22.6 25.5 23.0 30.1 34.4 27.9 25.0 23.0 40.5 33.5 29.0 2.6 35.2 29.7 39.8 33.1 19.6 9.9 10.3 12.0 15.4 9.7 10.8 10.2 10.0 9.8 9.7 10.7 10.6 32.4 25.6 37.8 49.0 36.1 17.3 23.3 39.3 31.9 101.4 24.8 31.9 36.2 45.8 39.7 22.0 81.3 32.1 47.2 10.6 121.3 36.3 1.7 22.5 29.1 30.4 22.3 11.1 49.3 38.3 9.7 31.3 22.4 17.2 30.9 28.0 28.2 48.7 36.0 84.1 63.5 24.6 30.5 27.7 20.7 4.0 44.1 24.5 14.2 40.3 49.6 87.0 64.9 74.9 96.0 29.3 19.2 47.4 26.2 18.9 32.1 55.5 28.6 97.5 32.9 38.3 39.4 18.2 17.9 28.5 18.8 14.0 34.9 36.4 24.2 23.5 XPC "RAD4, XPCC" ENSG00000154767 "XPC complex subunit, DNA damage recognition and repair factor" Q01831 3 14145147-14178621 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009932, HPA035707, HPA069673" Supported Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "CAB009932: AB_2241587, HPA035707: AB_2674743, HPA069673: AB_2686167" "unprognostic (7.46e-2)" "unprognostic (2.52e-2)" "unprognostic (4.50e-2)" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (2.54e-2)" "unprognostic (1.97e-1)" "unprognostic (5.65e-2)" "unprognostic (1.50e-1)" "unprognostic (7.13e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "prognostic favorable (4.14e-7)" "unprognostic (1.59e-1)" "unprognostic (7.88e-2)" "unprognostic (7.62e-2)" "prognostic favorable (2.46e-4)" 22.9 17.2 14.3 16.4 17.3 10.2 22.9 15.6 14.6 27.2 15.2 20.1 19.0 24.9 17.6 16.1 25.3 16.6 13.1 12.9 17.3 24.8 24.2 20.7 24.5 16.8 17.4 34.6 21.6 24.0 25.8 15.6 17.4 22.9 15.6 15.2 18.5 23.6 21.3 31.9 24.0 17.5 15.2 24.2 17.4 12.4 16.0 21.2 26.7 9.8 21.7 22.9 20.3 18.3 14.3 33.8 36.7 22.6 51.0 35.8 124.8 33.6 88.7 29.9 22.3 11.8 14.7 46.6 14.5 37.5 14.7 15.6 23.6 49.3 23.6 21.5 24.7 24.9 35.7 21.7 45.0 16.8 42.2 50.1 56.4 39.7 77.4 34.2 34.5 19.0 31.2 22.5 32.5 27.2 17.9 16.3 23.5 20.4 21.2 19.3 17.9 33.7 36.2 36.9 8.8 29.9 36.1 27.2 23.5 54.6 29.9 13.8 57.1 11.2 32.1 18.4 15.4 54.5 46.4 25.4 26.5 19.4 41.6 41.4 20.2 26.8 23.2 16.6 22.7 27.1 26.7 23.5 17.9 25.0 28.3 20.8 73.1 24.3 23.3 17.4 24.7 16.9 14.3 17.3 15.6 14.6 12.9 17.3 16.8 17.4 17.4 15.2 16.0 18.3 26.0 60.9 63.2 16.6 39.9 13.8 20.4 25.5 59.2 35.6 19.0 25.9 11.8 31.5 47.7 16.5 39.6 42.5 38.9 13.4 35.2 19.3 2.3 32.2 44.8 29.9 16.3 20.8 18.0 19.2 20.3 29.2 15.3 25.5 47.4 25.0 22.9 40.5 18.2 26.9 22.0 13.9 20.3 23.9 14.9 2.7 30.7 19.6 8.8 15.0 40.1 24.9 54.6 17.1 27.5 19.5 15.0 28.2 29.1 18.9 32.7 66.1 55.0 51.0 26.3 43.3 27.7 28.7 54.9 21.4 11.1 32.0 42.3 26.3 18.1 10.5 XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010184, HPA042933" Supported Enhanced "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 410000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "CAB010184: AB_2215817, HPA042933: AB_2678229" "unprognostic (7.34e-2)" "unprognostic (7.04e-2)" "unprognostic (6.37e-2)" "unprognostic (1.67e-2)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.84e-1)" "unprognostic (1.99e-3)" "unprognostic (4.43e-1)" "unprognostic (3.53e-3)" "unprognostic (4.90e-2)" "prognostic unfavorable (3.74e-4)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.43e-1)" "unprognostic (5.55e-2)" 33.2 29.8 30.1 48.7 31.4 25.8 39.2 35.7 44.3 37.9 31.6 34.9 24.7 52.5 37.0 35.1 45.9 32.0 36.0 27.9 33.7 30.8 41.7 31.9 65.3 28.9 30.5 58.9 26.2 38.5 22.0 52.1 30.4 34.2 42.0 52.0 19.9 34.9 37.5 34.2 33.2 48.6 30.9 43.4 31.9 54.5 32.8 73.6 38.8 47.2 60.9 38.6 22.4 38.9 169.1 152.9 194.1 135.8 91.4 107.9 145.5 166.6 109.2 192.9 151.8 217.3 114.7 256.0 117.4 127.1 186.3 125.0 307.9 126.5 268.6 151.6 110.7 242.8 136.2 148.4 55.4 234.6 145.4 62.9 103.8 149.4 145.9 126.0 149.5 108.7 285.5 127.7 164.9 97.8 212.6 100.4 213.1 189.9 111.5 175.6 208.0 148.1 103.0 124.9 152.8 77.5 174.2 142.8 87.1 185.6 108.6 110.8 98.9 153.7 178.7 137.2 175.0 102.8 203.2 347.0 96.8 214.0 151.0 3.3 1.4 2.2 1.8 2.2 1.9 1.1 1.0 1.8 2.1 0.7 1.0 1.0 0.6 2.7 1.2 1.6 1.2 1.2 30.1 31.4 35.7 44.3 27.9 33.7 28.9 30.5 30.4 30.9 32.8 38.9 42.0 41.7 43.2 114.3 55.3 52.1 32.1 45.5 78.6 67.5 40.2 38.6 64.5 38.6 38.7 31.3 95.9 54.1 56.6 27.3 13.7 29.7 4.2 58.6 79.7 47.7 45.1 73.2 87.9 26.1 49.3 49.9 42.3 68.6 41.8 100.4 41.4 55.8 57.2 72.3 101.3 34.2 40.7 55.3 58.4 11.9 33.5 63.9 37.4 68.4 64.2 33.4 61.8 83.4 102.5 32.3 20.9 30.9 57.2 55.6 21.0 22.2 56.9 101.7 19.7 50.5 55.7 65.9 91.6 83.3 56.8 30.1 54.5 54.4 46.2 47.7 XRCC1 RCC ENSG00000073050 "X-ray repair cross complementing 1" P18887 19 43543311-43580473 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005427, HPA006717" Supported Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "CAB005427: AB_2215661, HPA006717: AB_1858896" "unprognostic (1.10e-2)" "unprognostic (3.51e-3)" "unprognostic (4.59e-1)" "unprognostic (2.81e-2)" "unprognostic (4.08e-1)" "unprognostic (2.68e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (5.07e-2)" "unprognostic (3.12e-1)" "unprognostic (7.51e-2)" "unprognostic (3.00e-2)" "unprognostic (9.54e-2)" "unprognostic (1.07e-1)" "unprognostic (2.28e-1)" "unprognostic (9.34e-3)" "unprognostic (2.20e-2)" "unprognostic (5.69e-2)" 18.5 16.4 15.3 18.0 15.6 24.4 17.9 18.5 17.1 23.6 13.5 20.4 14.6 23.5 16.2 16.1 23.2 14.4 15.5 14.6 15.6 15.7 10.8 16.2 22.9 15.7 15.2 32.0 19.6 17.6 32.3 16.6 14.0 16.2 11.4 16.7 16.3 15.6 19.5 21.0 15.7 17.3 13.5 20.1 18.5 23.9 16.6 29.0 20.6 15.7 20.9 18.6 18.0 15.6 57.4 51.4 54.4 48.2 23.6 24.6 27.0 28.4 36.0 42.5 46.3 32.0 40.4 44.1 39.1 28.9 39.1 30.0 33.2 36.8 24.7 46.4 33.9 57.5 49.4 36.1 23.2 34.5 42.9 27.3 24.8 53.5 26.4 48.8 37.2 49.1 35.9 42.5 37.3 48.9 57.5 52.5 18.5 44.2 21.3 57.0 35.4 25.8 34.3 44.1 44.5 26.5 41.6 35.3 20.7 26.8 33.9 67.4 23.3 55.7 40.4 16.3 39.9 44.2 44.2 32.0 42.8 28.0 58.7 18.6 13.1 15.6 10.8 11.9 12.3 11.7 13.8 14.6 11.6 10.5 11.3 10.9 15.1 10.4 7.9 9.1 14.5 11.7 15.3 15.6 18.5 17.1 14.6 15.6 15.7 15.2 14.0 13.5 16.6 15.6 10.2 16.0 9.8 5.9 13.4 6.1 7.1 17.5 12.5 12.6 10.2 9.0 7.6 7.2 14.7 7.3 6.2 29.8 12.5 9.1 19.6 15.4 32.2 18.7 13.3 12.2 13.7 15.4 8.2 11.6 19.2 13.3 8.2 13.7 19.7 22.0 11.4 7.1 21.0 5.0 9.2 15.3 10.2 18.0 10.1 19.5 10.2 12.6 14.2 3.7 14.3 8.6 8.2 4.5 8.1 12.2 9.7 12.8 17.7 4.1 9.2 16.9 39.0 12.7 6.6 9.6 17.7 21.4 14.1 10.8 7.1 20.0 14.6 16.4 13.7 4.7 XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676141 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 14.1;Extravillous trophoblasts: 21.2;Granulosa cells: 20.2;Spermatocytes: 31.3;Spermatogonia: 19.1;Syncytiotrophoblasts: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Vesicles" "HPA065153: AB_2685422" "unprognostic (9.31e-3)" "unprognostic (8.25e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (9.10e-2)" "unprognostic (2.52e-2)" "unprognostic (3.36e-5)" "unprognostic (9.98e-3)" "unprognostic (5.82e-3)" "unprognostic (4.04e-3)" "unprognostic (1.06e-3)" "unprognostic (2.43e-2)" "unprognostic (1.55e-15)" "unprognostic (4.52e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-1)" "unprognostic (1.73e-2)" 0.2 0.2 0.9 2.3 0.6 5.3 1.5 1.6 2.8 0.3 0.0 1.1 1.7 1.1 0.9 1.0 0.5 0.4 1.0 0.6 1.9 0.4 0.4 0.5 2.9 0.6 0.6 1.0 0.0 0.6 0.0 2.1 1.4 0.7 1.7 1.9 0.2 0.4 0.1 1.9 1.5 0.5 1.1 1.0 1.0 3.0 1.0 3.6 0.6 0.0 2.5 0.5 0.1 1.9 16.5 10.4 18.3 15.8 1.1 1.8 15.0 11.8 3.9 8.2 10.3 14.7 12.8 24.8 9.5 3.5 13.7 13.7 12.8 7.1 19.3 8.9 17.3 16.8 15.5 10.0 0.3 27.3 9.3 0.9 1.1 15.6 3.6 2.0 3.8 15.5 34.2 22.8 8.3 12.6 32.4 21.2 21.6 10.8 12.9 22.8 19.3 15.3 3.1 10.3 16.7 18.1 11.7 7.6 5.0 11.3 5.4 8.3 4.2 17.2 6.9 13.3 23.0 8.8 14.5 19.0 11.0 20.9 20.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.6 1.6 2.8 0.6 1.9 0.6 0.6 1.4 1.1 1.0 1.9 0.2 0.0 1.1 1.6 1.9 1.3 1.0 1.0 0.0 4.9 0.8 0.4 2.9 0.0 1.4 1.8 0.0 11.2 0.4 0.9 0.0 1.1 11.7 0.9 1.9 1.1 0.0 14.1 2.3 0.2 21.2 2.5 3.1 1.4 0.0 20.2 1.1 0.2 2.4 0.0 2.0 1.7 2.0 0.6 0.8 4.9 0.9 0.8 0.0 0.0 0.6 1.1 3.1 4.5 2.0 0.5 0.1 1.2 6.1 0.6 0.3 0.3 0.1 2.3 0.0 1.9 1.8 31.3 19.1 2.7 1.4 12.6 2.2 1.2 2.3 1.0 XRCC3 ENSG00000126215 "X-ray repair cross complementing 3" O43542 14 103697609-103715504 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 10.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062422, HPA068953" Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA062422: AB_2684757, HPA068953: AB_2686062" "unprognostic (2.52e-2)" "unprognostic (1.81e-3)" "unprognostic (6.75e-2)" "unprognostic (4.01e-2)" "unprognostic (4.29e-1)" "unprognostic (1.83e-1)" "unprognostic (2.53e-4)" "unprognostic (2.93e-2)" "unprognostic (4.67e-2)" "unprognostic (1.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.53e-2)" "unprognostic (3.52e-7)" "unprognostic (1.27e-1)" "unprognostic (1.57e-1)" "unprognostic (8.84e-2)" "unprognostic (3.72e-2)" 9.8 6.0 8.7 8.7 12.5 31.9 9.3 7.2 10.3 13.7 11.9 11.1 6.9 10.4 1.7 13.9 10.9 6.6 8.3 6.6 5.8 7.9 7.7 12.1 15.4 13.6 9.7 12.7 9.8 1.7 8.6 5.2 9.7 13.4 7.5 4.5 12.7 3.3 12.4 39.0 12.6 2.8 7.7 21.3 9.1 13.8 9.7 10.0 10.5 2.5 11.0 9.6 12.4 14.3 32.4 58.4 31.5 38.5 2.8 7.9 57.0 35.5 11.6 48.9 52.3 32.4 50.3 51.8 29.5 7.5 38.4 50.3 34.6 52.4 29.9 31.3 36.1 50.6 31.6 30.4 4.9 45.3 30.8 6.0 5.2 43.2 26.7 10.4 20.2 51.3 31.8 30.4 25.2 70.7 79.6 35.8 26.4 47.1 42.0 63.7 45.7 19.8 10.5 44.2 31.1 25.7 41.3 21.7 14.3 17.4 34.6 35.0 17.5 25.1 28.9 80.0 38.8 26.2 25.8 63.7 15.6 36.9 38.4 0.7 0.5 0.9 1.0 0.9 1.0 1.1 0.8 0.8 0.5 0.9 0.8 0.5 0.3 0.7 0.7 0.4 0.6 1.3 8.7 12.5 7.2 10.3 6.6 5.8 13.6 9.7 9.7 7.7 9.7 14.3 2.2 0.0 0.0 2.6 2.5 1.5 1.9 2.1 1.8 1.7 3.2 3.6 0.2 2.8 2.5 0.0 2.1 10.2 1.8 6.9 1.9 1.5 0.7 1.9 2.2 2.0 1.2 7.4 2.6 1.8 6.1 1.2 0.5 2.0 0.0 4.7 0.4 0.3 4.4 3.3 1.0 7.4 0.0 0.0 2.0 1.8 0.3 1.5 0.0 1.0 1.5 1.7 2.1 1.5 1.4 1.7 2.6 1.2 4.4 1.6 0.7 0.2 1.7 2.3 0.0 2.6 1.2 3.1 5.8 2.8 1.3 3.1 2.0 4.2 8.3 1.2 XRCC4 ENSG00000152422 "X-ray repair cross complementing 4" Q13426 5 83077498-83353787 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 80.8;Pancreatic endocrine cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 61.6" "Low region specificity" "Detected in all" "HPA006801, HPA051538" Supported Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "HPA006801: AB_1858899, HPA051538: AB_2681526" "prognostic unfavorable (1.80e-5)" "unprognostic (3.05e-2)" "unprognostic (5.12e-2)" "unprognostic (3.91e-3)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (1.44e-3)" "unprognostic (2.23e-2)" "unprognostic (2.19e-2)" "unprognostic (5.77e-2)" "unprognostic (2.38e-2)" "unprognostic (8.24e-2)" "unprognostic (4.46e-2)" "unprognostic (1.79e-1)" "unprognostic (1.97e-1)" "unprognostic (2.34e-1)" "unprognostic (6.91e-2)" 4.4 4.2 2.8 6.0 3.1 4.4 6.1 3.1 3.9 3.1 2.5 5.9 7.6 3.5 3.2 3.8 3.9 5.2 7.9 3.2 3.3 7.2 5.4 4.7 8.5 3.2 3.1 2.3 2.5 2.4 2.1 5.4 3.2 3.9 5.7 2.3 3.4 4.3 2.6 3.3 5.1 3.9 3.3 4.8 4.3 8.8 3.0 10.3 4.3 2.4 9.0 5.5 2.9 3.4 15.1 11.7 14.1 12.5 7.8 11.3 13.2 13.7 11.2 14.8 17.3 10.0 21.8 20.9 10.3 11.0 21.2 12.8 9.4 30.7 24.2 10.0 11.8 11.1 8.3 12.4 5.2 12.5 17.2 7.9 14.3 19.3 10.8 15.6 12.4 13.8 8.2 9.8 17.6 12.1 23.1 16.0 7.9 8.8 17.2 19.0 61.6 20.7 14.1 6.8 9.2 11.8 8.9 6.5 18.4 11.8 13.2 19.5 7.8 8.2 17.6 8.9 19.0 7.8 12.3 26.6 14.8 22.2 13.5 17.6 17.3 12.4 5.9 25.8 6.1 9.3 6.2 6.5 13.6 8.8 8.3 6.8 16.5 15.2 25.4 10.1 7.7 9.1 2.8 3.1 3.1 3.9 3.2 3.3 3.2 3.1 3.2 3.3 3.0 3.4 10.4 16.0 5.5 39.8 13.0 5.4 13.2 28.0 5.2 4.7 5.5 5.0 15.3 8.6 19.2 5.5 0.0 17.4 12.9 7.6 15.6 17.4 10.2 14.8 12.6 8.9 0.0 6.3 16.6 28.4 38.9 11.6 11.2 10.0 10.8 11.9 11.4 5.5 19.1 1.7 18.7 7.8 22.4 20.7 12.1 5.9 7.8 20.5 8.8 30.9 25.1 7.8 14.4 53.3 80.8 65.7 6.7 7.2 11.3 4.4 7.2 26.5 16.9 4.5 0.0 4.6 11.9 33.1 25.3 7.1 4.4 11.9 12.6 8.0 6.2 8.2 XRCC5 "KARP-1, KU80, Ku86, KUB2" ENSG00000079246 "X-ray repair cross complementing 5" P13010 2 216107464-216206303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004468, HPA025813, HPA064685" Supported Enhanced Nucleoplasm NA NA 940000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004468: AB_672929, HPA025813: AB_1858901, HPA064685: AB_2685322" "unprognostic (4.23e-2)" "unprognostic (1.75e-1)" "unprognostic (9.07e-3)" "unprognostic (3.44e-3)" "unprognostic (2.44e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (2.10e-7)" "unprognostic (4.42e-3)" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (3.38e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-1)" "unprognostic (2.88e-2)" "unprognostic (3.58e-2)" "unprognostic (6.01e-2)" 79.6 74.0 52.8 102.4 58.4 112.0 114.6 56.0 69.9 96.4 38.1 91.0 82.2 103.3 85.3 96.8 95.8 83.2 77.1 58.1 56.4 100.2 140.6 76.6 127.8 52.4 50.7 104.0 71.7 118.4 61.4 87.1 54.4 84.7 106.6 102.0 71.6 91.3 103.1 91.6 82.3 100.1 59.1 83.9 77.0 69.5 51.0 176.8 129.2 92.7 140.9 131.7 72.7 65.6 234.4 194.9 427.0 230.5 185.5 210.9 256.6 269.9 279.2 307.1 328.5 421.0 225.7 225.6 214.8 239.1 269.2 203.5 425.2 329.5 469.7 215.0 291.0 488.5 282.9 398.0 229.2 437.1 230.0 193.5 172.1 361.2 156.6 218.4 368.0 272.1 314.4 199.7 405.9 225.9 496.7 221.7 498.0 236.0 170.6 429.8 376.7 186.5 331.9 262.6 372.6 314.6 217.8 159.9 201.1 428.5 196.7 325.8 264.2 287.3 241.5 190.6 312.3 240.0 311.4 493.6 223.4 339.5 290.0 253.2 172.7 175.0 153.6 177.1 165.3 121.2 148.1 157.0 168.0 121.6 147.6 149.1 192.7 172.9 217.4 102.1 167.5 330.4 52.8 58.4 56.0 69.9 58.1 56.4 52.4 50.7 54.4 59.1 51.0 65.6 129.0 105.8 126.3 65.6 131.0 113.7 174.0 242.4 90.5 136.7 93.6 87.1 163.0 105.8 190.0 101.2 45.9 210.5 141.6 79.8 97.8 304.3 103.0 147.4 175.4 142.4 133.3 159.4 73.9 235.8 238.8 134.1 74.5 159.1 146.7 140.2 82.8 222.5 157.3 89.2 82.4 90.7 173.0 100.5 85.3 30.0 101.5 130.7 69.4 108.7 310.9 142.0 138.0 93.0 111.4 247.9 70.3 129.4 132.5 137.4 82.8 139.9 160.1 114.0 111.7 142.9 161.3 252.2 179.2 114.7 120.3 165.5 149.7 165.3 112.0 161.2 XRCC6 "D22S671, D22S731, G22P1, KU70, ML8" ENSG00000196419 "X-ray repair cross complementing 6" P12956 22 41621163-41664048 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 579.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004254, HPA047549, HPA062226" Enhanced Enhanced Nucleoplasm No No 700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004254: AB_628453, HPA047549: AB_2680085, HPA062226: AB_2684716" "unprognostic (5.55e-2)" "unprognostic (2.39e-2)" "unprognostic (1.82e-3)" "unprognostic (2.39e-1)" "unprognostic (2.47e-2)" "unprognostic (9.17e-2)" "unprognostic (1.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.89e-2)" "unprognostic (1.33e-1)" "unprognostic (2.06e-3)" "unprognostic (1.22e-1)" "unprognostic (2.28e-1)" "unprognostic (4.77e-2)" "unprognostic (7.95e-2)" 143.7 183.4 84.9 153.4 89.3 218.2 143.3 87.8 100.8 152.1 87.2 159.5 136.8 153.8 111.3 192.1 151.4 105.5 176.1 89.2 94.7 136.9 142.4 133.2 196.6 89.5 86.8 169.8 119.0 156.5 122.6 155.0 92.2 132.7 164.9 115.6 130.8 144.4 273.0 168.3 142.8 161.0 93.5 143.1 138.6 231.2 87.9 224.1 137.8 184.3 222.2 162.6 142.0 96.4 554.6 388.0 527.9 455.5 313.5 279.5 413.8 394.7 464.6 794.9 656.4 570.4 335.7 886.2 319.8 478.1 357.4 400.6 739.2 486.8 803.2 493.4 921.2 478.8 435.2 559.5 281.5 1142.2 520.5 252.7 323.1 501.2 275.0 319.8 505.6 371.6 470.2 360.1 523.1 589.9 589.0 390.6 482.1 1138.4 452.1 660.0 562.3 695.6 440.4 404.4 243.3 174.6 644.1 328.2 455.7 392.9 382.2 439.0 366.2 394.3 546.2 354.0 522.4 354.0 671.9 896.1 369.4 441.3 476.4 146.0 264.3 227.6 243.6 296.5 258.4 256.5 269.5 269.2 324.1 246.9 293.2 262.5 69.2 253.2 307.0 191.7 325.9 600.8 84.9 89.3 87.8 100.8 89.2 94.7 89.5 86.8 92.2 93.5 87.9 96.4 96.6 96.1 142.5 18.6 132.6 124.0 201.0 219.0 83.1 107.1 80.1 83.4 89.4 115.8 160.4 82.8 62.6 422.3 104.9 97.3 166.3 205.4 119.6 86.1 87.0 117.0 98.6 125.4 24.5 182.7 317.2 123.9 73.4 105.9 119.7 156.4 70.3 103.7 170.2 87.5 29.5 114.7 166.8 98.1 116.7 62.9 126.8 110.4 88.9 17.8 182.8 149.7 89.6 26.2 30.5 150.9 106.6 126.7 116.0 112.0 113.7 140.3 112.6 103.6 164.3 102.4 127.4 579.8 314.4 91.5 102.1 362.2 136.9 150.6 166.8 137.5 YBX1 "BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1" ENSG00000065978 "Y-box binding protein 1" P67809 1 42682418-42703805 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2038.9" "Cell type enhanced" "Detected in all" "Early spermatids: 8388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005875, HPA040304, HPA057159" Supported Supported "Endoplasmic reticulum,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Endoplasmic reticulum, Vesicles, Plasma membrane" "CAB005875: AB_2219278, HPA040304: AB_10795364, HPA057159: AB_2683355" "unprognostic (8.59e-2)" "unprognostic (5.16e-2)" "unprognostic (9.27e-3)" "unprognostic (2.68e-3)" "unprognostic (7.76e-2)" "unprognostic (8.03e-3)" "prognostic unfavorable (9.87e-10)" "unprognostic (2.80e-2)" "unprognostic (2.31e-2)" "unprognostic (2.79e-3)" "unprognostic (7.51e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (3.59e-7)" "unprognostic (3.66e-2)" "unprognostic (2.44e-1)" "unprognostic (1.94e-2)" "unprognostic (3.25e-1)" 532.0 254.5 141.7 422.4 155.4 863.9 401.1 153.3 157.7 331.8 154.4 600.2 364.9 406.2 211.3 365.0 337.0 209.8 789.7 140.6 159.4 318.9 309.9 396.3 407.9 175.1 160.2 311.7 266.7 133.8 122.2 242.2 178.8 307.8 378.1 391.8 270.5 219.5 2038.9 295.0 366.1 338.9 152.7 367.1 405.0 783.5 180.8 353.4 282.0 1133.9 382.2 501.5 332.3 173.5 1552.8 761.5 1020.4 1232.7 991.0 908.1 1200.2 971.5 768.9 1116.6 875.8 1034.6 1253.7 1630.6 1157.5 825.2 495.5 870.2 1162.6 1230.5 1103.9 1087.8 1278.0 1596.4 1491.9 1343.8 786.7 2214.4 1320.7 812.6 1092.3 1094.5 1365.7 630.0 950.3 1271.9 1823.0 720.6 1104.0 837.7 2816.5 2464.6 2902.1 755.0 1006.4 1789.6 1972.5 1938.2 1176.7 933.8 1731.6 1298.5 893.7 1294.0 2038.3 1096.8 443.2 5002.2 862.6 945.4 1748.6 1371.1 2209.3 1213.7 1670.6 2004.8 910.4 1750.3 1049.9 15.3 48.4 69.9 42.9 107.1 52.9 69.4 51.8 43.3 77.4 61.2 44.0 45.9 9.0 35.1 124.2 58.6 69.7 34.1 141.7 155.4 153.3 157.7 140.6 159.4 175.1 160.2 178.8 152.7 180.8 173.5 701.7 173.1 230.9 16.3 818.3 1397.7 1265.9 419.7 747.3 247.8 569.7 564.5 1072.3 441.8 355.5 325.5 150.1 753.9 678.4 620.6 1457.6 1013.6 8388.7 363.5 695.5 755.1 587.8 2244.2 16.2 886.6 1998.9 687.6 461.3 427.0 383.1 489.1 483.3 480.1 1708.7 121.1 27.1 930.2 354.0 1656.0 2342.9 3743.4 751.2 1307.6 905.4 19.7 1171.0 463.8 744.6 23.6 32.7 858.2 975.1 806.1 981.0 1935.1 993.3 1169.8 196.2 602.4 466.8 754.8 1083.7 3245.2 425.5 1113.5 1302.5 481.5 635.6 811.4 1257.7 1697.8 YWHAB YWHAA ENSG00000166913 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta" P31946 20 44885702-44908532 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003759, HPA007925, HPA011212" Enhanced Supported Cytosol NA NA 97000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB003759: AB_289588, HPA007925: AB_1844340, HPA011212: AB_1844334" "prognostic unfavorable (9.18e-4)" "unprognostic (1.48e-1)" "unprognostic (9.06e-2)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.80e-1)" "prognostic unfavorable (6.14e-4)" "prognostic unfavorable (1.91e-6)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.92e-2)" "unprognostic (2.01e-1)" "unprognostic (1.53e-2)" "unprognostic (2.35e-1)" "prognostic favorable (2.52e-5)" "unprognostic (6.72e-2)" "unprognostic (2.40e-1)" "unprognostic (6.60e-3)" "unprognostic (8.59e-2)" 133.1 120.6 214.6 140.0 225.1 111.1 106.8 156.3 275.9 103.7 155.9 160.8 128.4 102.0 83.5 148.3 97.6 97.6 105.0 232.0 221.6 155.6 96.7 126.4 174.3 187.5 175.4 81.2 58.1 123.1 48.3 123.2 187.7 99.9 173.5 114.9 83.8 133.4 85.7 129.9 135.3 142.6 174.1 162.3 123.5 56.8 201.5 139.1 118.1 78.6 210.3 153.5 91.6 195.0 306.5 227.8 179.5 173.2 291.0 255.5 238.9 270.8 263.2 327.7 284.6 479.6 336.9 324.2 272.6 361.9 355.5 315.5 256.1 506.0 388.0 124.1 153.1 242.4 180.8 285.8 192.6 396.8 223.6 201.4 370.4 257.2 328.4 223.6 333.5 196.0 265.6 152.6 340.9 363.2 312.1 325.3 169.7 348.9 341.6 240.3 259.5 251.1 352.3 336.6 189.8 202.6 459.9 485.7 331.1 207.7 354.6 376.3 381.2 504.6 259.7 288.8 281.2 100.4 196.9 292.5 369.9 260.8 263.5 105.5 95.2 90.5 71.3 130.8 74.0 71.2 89.3 87.7 102.8 66.5 70.6 86.2 93.4 72.4 155.4 65.9 113.8 71.9 214.6 225.1 156.3 275.9 232.0 221.6 187.5 175.4 187.7 174.1 201.5 195.0 421.4 253.2 289.0 35.6 292.8 276.7 256.0 270.8 195.2 239.9 229.6 199.3 197.1 200.1 236.5 248.3 50.1 358.6 317.2 532.6 230.9 476.1 17.7 183.0 274.2 351.5 298.1 183.4 93.8 489.8 627.7 246.4 192.7 278.5 227.9 262.8 300.9 155.9 410.3 292.7 64.1 388.4 160.7 394.5 329.9 24.2 188.9 418.7 222.3 51.5 543.5 229.0 295.5 25.6 63.0 654.9 429.9 210.3 301.8 419.0 328.9 364.5 206.4 131.5 230.1 173.3 337.8 51.1 171.3 333.3 325.3 531.3 369.3 394.2 382.4 440.5 YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350" Approved Supported Cytosol NA NA 83000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016200: AB_626619, CAB021109: AB_10060396, CAB047350: , HPA008445: AB_1844336" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "prognostic favorable (6.48e-6)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.73e-2)" "unprognostic (4.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.73e-1)" "unprognostic (1.92e-3)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (8.94e-2)" 221.9 198.9 251.8 122.8 264.2 121.3 198.7 266.3 272.8 168.8 195.7 161.1 136.8 155.6 192.7 239.1 188.1 103.7 242.3 260.7 275.4 229.3 211.7 176.9 113.7 271.1 246.8 170.8 154.9 236.9 178.8 198.2 267.1 150.0 168.1 220.8 184.8 121.6 656.7 193.3 129.3 137.3 279.2 101.5 136.9 165.4 262.2 211.0 208.5 441.8 164.5 186.9 179.7 302.7 615.3 565.8 700.2 563.4 376.9 454.7 589.8 382.1 481.5 724.5 571.3 907.5 305.5 524.7 411.9 621.9 439.7 463.1 859.2 745.6 798.7 294.2 930.9 334.1 366.2 409.4 483.4 277.1 311.1 421.6 458.6 619.3 897.0 520.6 729.2 458.5 402.8 337.9 719.7 368.5 445.8 264.1 566.6 596.9 332.7 477.3 255.9 380.4 547.7 365.7 354.2 497.2 531.1 240.3 364.3 439.9 442.3 290.9 467.4 411.9 293.8 453.7 731.4 190.5 329.9 346.6 478.4 387.5 585.4 78.6 137.2 41.2 47.3 153.6 57.8 78.1 67.3 55.1 180.3 59.1 55.7 51.2 49.9 64.1 144.8 133.8 99.7 151.0 251.8 264.2 266.3 272.8 260.7 275.4 271.1 246.8 267.1 279.2 262.2 302.7 363.6 298.1 194.4 83.2 161.1 573.9 457.5 468.4 281.7 153.6 313.6 219.1 473.4 265.9 310.9 371.5 50.1 463.2 128.7 300.7 745.4 460.8 258.0 573.6 414.3 352.6 352.6 244.7 73.4 421.4 709.5 319.4 194.7 502.7 211.5 328.1 262.3 309.0 384.9 111.0 72.4 346.3 376.4 260.9 434.9 434.3 280.8 227.5 425.2 60.0 320.5 357.8 55.6 56.8 112.1 464.8 289.8 294.9 279.5 487.9 272.1 707.8 504.6 173.3 243.3 361.2 524.6 508.7 573.3 333.8 586.6 519.5 130.7 287.2 361.1 474.4 YWHAH YWHA1 ENSG00000128245 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta" Q04917 22 31944522-31957603 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 501.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025918 Uncertain NA NA 42000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "CAB025918: " "unprognostic (3.77e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-2)" "unprognostic (1.86e-2)" "unprognostic (1.13e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.59e-5)" "unprognostic (8.62e-2)" "unprognostic (1.63e-1)" "unprognostic (4.51e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.40e-1)" "unprognostic (1.59e-1)" "unprognostic (5.60e-2)" "unprognostic (7.00e-2)" "unprognostic (6.81e-2)" 104.9 82.7 244.8 87.2 309.8 86.8 76.6 96.2 501.2 54.6 4.6 106.3 64.8 68.7 92.8 60.4 73.1 82.4 78.1 386.6 217.9 77.6 61.4 112.2 68.3 156.7 109.2 53.0 69.6 29.5 64.4 100.0 145.9 57.8 111.1 114.1 59.4 70.9 68.7 65.0 68.9 131.0 74.1 57.9 109.3 16.2 118.1 70.4 62.0 54.8 82.4 89.9 58.3 229.8 344.5 142.4 180.8 91.8 112.7 107.0 97.0 321.9 172.0 208.1 228.6 157.8 124.2 202.8 76.6 329.4 116.6 169.1 208.7 183.7 271.4 177.0 157.7 118.7 108.2 156.8 108.5 391.4 132.8 84.9 113.0 176.9 135.6 137.3 201.3 76.9 171.5 155.6 249.6 148.5 121.0 189.8 185.2 197.1 150.8 173.7 201.2 115.1 216.5 153.1 323.5 104.4 184.2 134.7 124.7 245.9 78.2 119.3 248.4 206.0 190.1 138.2 216.6 80.7 130.5 257.7 137.3 162.0 170.9 11.9 19.8 22.0 7.6 16.8 11.1 12.4 9.4 10.8 22.9 13.0 3.7 4.9 11.6 25.4 18.4 6.2 19.5 14.0 244.8 309.8 96.2 501.2 386.6 217.9 156.7 109.2 145.9 74.1 118.1 229.8 259.0 51.3 21.7 27.1 106.6 334.1 223.5 27.3 125.2 54.8 123.6 79.0 51.2 125.8 26.5 126.9 22.9 171.7 53.0 242.8 232.8 148.0 3.9 180.0 81.1 211.7 75.4 269.8 132.0 160.6 145.4 118.8 139.1 153.0 40.0 33.4 120.3 72.1 245.6 53.8 62.9 125.4 34.6 155.6 269.8 13.7 61.2 397.6 300.6 66.5 102.1 80.1 44.3 22.1 42.0 203.3 115.7 80.9 120.4 240.7 93.4 125.5 52.5 73.7 157.8 55.8 197.1 23.3 35.5 164.1 340.0 34.8 95.2 25.7 116.1 191.8 ZBTB16 "PLZF, ZNF145" ENSG00000109906 "Zinc finger and BTB domain containing 16" Q05516 11 114059711-114256765 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 105.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.8;Inhibitory neurons: 125.9;NK-cells: 119.4;Skeletal myocytes: 163.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 23.3;MAIT T-cell: 39.4;naive B-cell: 11.0;NK-cell: 10.9" "Group enriched" "Detected in many" 5 "B-cells: 11.0;NK-cells: 10.9;T-cells: 39.4" "Cell line enhanced" "Detected in some" "ASC diff: 71.5;ASC TERT1: 38.6;HEL: 40.7;HHSteC: 26.6;HSkMC: 26.7;hTCEpi: 30.6;hTERT-HME1: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001499, CAB004540" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB004540: AB_2218941, HPA001499: AB_1079640" "unprognostic (2.21e-1)" "unprognostic (2.17e-1)" "unprognostic (7.30e-2)" "unprognostic (1.18e-1)" "unprognostic (2.53e-1)" "unprognostic (3.05e-1)" "unprognostic (1.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-4)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.21e-4)" "unprognostic (2.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" 55.8 20.8 5.1 3.4 14.9 7.6 32.3 11.7 24.8 25.9 17.7 20.9 0.9 29.6 4.0 28.1 30.9 13.1 28.1 9.9 8.4 10.6 14.5 27.1 8.8 20.1 8.4 51.4 61.7 34.3 6.4 9.6 15.2 15.1 3.3 2.2 13.3 7.0 88.6 28.5 16.3 15.8 4.9 13.2 18.3 4.0 7.1 6.5 29.3 105.8 2.0 29.4 19.7 18.0 0.0 0.0 13.0 0.0 71.5 38.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 40.7 0.0 0.0 26.6 0.9 0.7 26.7 30.6 0.0 25.6 0.0 4.6 5.5 0.1 0.0 0.8 0.0 2.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 4.2 1.2 23.3 1.2 39.4 0.4 1.2 3.5 0.1 11.0 1.3 0.6 0.3 10.9 1.2 0.0 0.4 5.7 5.1 14.9 11.7 24.8 9.9 8.4 20.1 8.4 15.2 4.9 7.1 18.0 95.3 22.4 7.7 59.1 16.3 11.1 81.7 7.7 8.6 32.6 12.6 16.8 35.1 42.9 7.1 9.2 0.0 0.1 51.2 0.7 1.9 1.9 21.1 1.7 41.3 49.5 7.2 18.1 134.8 0.9 0.2 59.8 1.1 3.8 14.5 38.2 65.7 50.9 0.8 0.0 125.9 3.7 8.2 27.0 5.3 27.7 89.8 32.1 7.2 65.6 7.6 20.2 119.4 45.8 43.4 0.3 0.1 92.2 17.7 38.6 28.8 6.6 6.8 1.9 105.2 163.9 75.3 0.4 9.9 1.8 6.8 0.3 27.8 0.2 3.5 9.4 ZFHX3 "ATBF1, C16orf47, FLJ26184, ZNF927" ENSG00000140836 "Zinc finger homeobox 3" Q15911 16 72782885-73891871 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Myogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 47 "brain: 501.8" "Cell type enhanced" "Detected in all" "Microglial cells: 285.8;Smooth muscle cells: 177.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebral cortex: 501.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059353 Uncertain Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA059353: AB_2683987" "prognostic unfavorable (1.55e-4)" "unprognostic (3.57e-2)" "unprognostic (1.68e-1)" "unprognostic (2.03e-2)" "unprognostic (2.81e-2)" "unprognostic (3.12e-1)" "unprognostic (4.24e-2)" "unprognostic (6.36e-2)" "unprognostic (9.94e-3)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "unprognostic (4.16e-2)" "prognostic favorable (1.37e-5)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.15e-2)" 6.0 4.3 5.9 1.9 5.8 0.9 3.6 2.8 501.8 5.2 7.1 6.0 1.5 4.7 4.0 2.0 3.6 4.2 3.5 68.3 12.1 3.2 3.1 4.3 1.2 72.3 13.7 2.8 4.0 9.7 3.9 6.2 49.5 6.9 2.6 4.5 4.0 6.4 9.9 2.6 2.6 4.1 11.3 3.1 3.6 1.8 12.5 1.3 7.4 10.7 0.7 6.8 3.5 56.5 5.0 9.2 14.7 12.3 5.3 6.7 15.1 3.9 4.3 2.5 2.8 10.6 2.9 2.3 5.5 7.5 3.4 3.5 9.4 4.7 3.4 9.3 2.3 0.4 13.1 15.1 4.9 1.6 3.5 2.5 2.8 7.3 6.5 2.3 4.7 1.0 1.1 0.6 6.3 10.9 0.5 3.1 2.4 2.7 1.5 7.0 4.0 0.8 4.0 8.8 10.9 3.9 6.9 2.1 4.8 6.7 3.0 0.7 10.3 6.0 7.0 6.5 4.9 4.7 1.7 1.6 2.9 1.4 4.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.2 0.0 0.0 5.9 5.8 2.8 501.8 68.3 12.1 72.3 13.7 49.5 11.3 12.5 56.5 13.6 70.5 26.7 109.7 8.6 17.0 55.6 13.1 37.0 122.0 24.5 20.6 23.7 47.1 34.8 47.8 22.9 47.4 5.2 11.0 5.9 23.0 2.6 94.6 33.1 40.3 26.9 7.4 22.0 23.4 19.4 68.8 25.5 154.6 21.0 20.7 44.6 37.5 67.0 23.5 8.7 23.2 22.4 84.2 142.6 2.8 10.5 72.9 21.4 285.8 40.8 13.9 3.1 83.9 18.5 20.7 22.4 19.9 2.2 77.5 6.9 7.4 29.3 34.1 124.9 153.7 177.3 3.7 16.8 29.5 17.2 62.1 7.7 12.4 31.0 43.8 ZFP36L1 "Berg36, BRF1, cMG1, ERF1, RNF162B, TIS11B" ENSG00000185650 "ZFP36 ring finger protein like 1" Q07352 14 68787660-68796253 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA transport, Transport" "Developmental protein, DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1973.2;Squamous epithelial cells: 2019.8;Suprabasal keratinocytes: 3223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 2901.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 2901.2" "Cell line enhanced" "Detected in all" "hTERT-HME1: 462.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001301 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA001301: AB_1080644" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (1.27e-1)" "unprognostic (1.64e-2)" "unprognostic (1.11e-1)" "unprognostic (2.17e-2)" "unprognostic (3.81e-3)" "unprognostic (1.13e-3)" "unprognostic (1.30e-1)" "unprognostic (1.11e-2)" "unprognostic (6.45e-3)" "unprognostic (5.77e-2)" "unprognostic (2.97e-1)" "unprognostic (5.68e-2)" 342.7 107.9 108.1 218.2 108.3 84.0 305.6 118.0 96.1 466.4 91.7 335.1 127.5 423.1 107.7 293.0 303.3 174.9 178.8 98.7 184.1 157.8 260.1 242.7 199.5 207.8 187.5 453.5 225.4 161.7 67.3 315.8 145.0 222.3 104.2 57.5 319.3 201.7 93.1 511.3 151.5 316.0 162.7 178.5 196.9 49.3 142.6 130.1 190.6 89.6 150.4 335.8 467.0 166.8 235.6 211.8 94.7 139.0 234.4 187.2 203.9 96.4 169.6 59.1 72.9 93.9 159.5 58.4 59.5 177.4 85.5 108.4 8.8 313.8 70.0 27.9 13.2 21.5 115.0 68.2 133.8 3.3 24.3 157.6 396.4 69.1 462.1 195.2 119.2 17.1 61.5 113.7 314.4 54.1 9.3 11.1 78.7 105.1 31.7 150.5 127.1 17.8 213.4 155.3 1.0 2.5 113.7 163.4 87.8 131.9 148.3 3.0 254.4 167.3 122.8 139.0 101.0 62.9 32.9 39.9 213.5 1.4 66.9 230.8 240.9 3.9 211.1 244.7 197.2 266.0 168.8 150.3 123.8 461.4 179.3 162.2 2901.2 154.3 176.1 16.2 174.5 257.5 108.1 108.3 118.0 96.1 98.7 184.1 207.8 187.5 145.0 162.7 142.6 166.8 830.2 477.5 415.6 172.7 513.8 1333.5 761.2 830.2 1973.2 4.6 750.7 504.4 84.2 420.4 523.9 364.1 0.0 442.1 276.5 164.4 84.1 575.8 97.0 434.6 479.6 571.0 20.4 87.7 1.5 573.1 476.6 894.3 218.6 656.2 200.8 21.1 292.7 595.6 548.3 0.0 0.7 225.3 215.7 613.9 1272.8 72.2 502.0 670.0 528.3 142.4 499.0 211.9 131.8 63.8 0.9 544.8 138.3 397.2 191.7 657.7 138.4 143.7 314.5 9.2 269.5 562.0 714.4 12.2 13.3 2019.8 3223.6 898.7 405.2 157.1 191.1 817.8 ZFP36L2 "BRF2, ERF2, RNF162C, TIS11D" ENSG00000152518 "ZFP36 ring finger protein like 2" P47974 2 43222402-43226606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Developmental protein, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1727.3;Basal squamous epithelial cells: 2181.9;Plasma cells: 2029.3;Suprabasal keratinocytes: 1549.6;T-cells: 1760.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047428 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA047428: AB_10963428" "unprognostic (2.07e-2)" "unprognostic (1.81e-2)" "unprognostic (9.77e-2)" "unprognostic (6.10e-2)" "unprognostic (9.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-1)" "unprognostic (7.62e-3)" "unprognostic (2.04e-1)" "unprognostic (4.50e-2)" "unprognostic (9.67e-3)" "unprognostic (1.65e-1)" "unprognostic (1.96e-2)" "unprognostic (2.50e-1)" "unprognostic (4.52e-2)" "unprognostic (1.23e-1)" "unprognostic (2.98e-2)" 187.0 110.8 33.0 150.1 39.9 195.2 175.0 41.0 31.9 141.5 36.9 130.3 113.6 101.7 38.7 103.7 121.1 124.1 97.6 28.5 45.6 64.7 91.4 169.7 171.1 109.1 50.3 187.4 78.7 19.9 37.7 31.7 51.9 123.1 132.5 17.0 92.5 63.8 64.9 219.9 171.2 65.2 58.5 120.7 127.2 19.2 51.5 160.9 180.8 42.1 121.9 93.5 133.7 45.7 36.2 17.4 17.0 9.5 208.0 211.4 6.9 51.7 93.1 21.6 16.4 61.0 16.7 26.0 37.9 59.7 12.0 66.9 18.2 89.9 18.3 46.6 38.0 42.0 6.4 65.1 61.8 92.3 35.0 149.8 143.4 22.1 143.2 32.6 38.9 39.1 42.6 100.1 21.4 192.0 109.4 190.8 26.0 113.2 30.1 81.0 12.7 151.7 36.9 51.5 15.0 37.6 9.8 58.9 32.2 23.2 10.0 150.4 18.6 58.3 25.2 49.7 32.1 84.1 25.1 39.0 19.6 227.7 27.5 18.7 42.5 82.1 46.6 35.3 45.8 18.1 46.1 62.8 51.2 22.7 34.1 33.9 61.6 52.7 28.1 22.0 19.5 30.0 33.0 39.9 41.0 31.9 28.5 45.6 109.1 50.3 51.9 58.5 51.5 45.7 540.1 48.1 67.1 91.1 1144.2 1727.3 1232.0 76.3 2181.9 3.7 455.0 420.5 120.8 420.4 72.4 136.1 0.0 12.2 1167.2 470.8 84.1 37.2 2.4 192.4 241.9 371.7 187.8 340.6 0.4 37.0 22.2 635.9 562.7 292.0 138.5 497.7 185.6 146.8 236.5 0.0 0.6 538.1 26.4 436.2 435.2 12.5 311.9 579.7 302.4 97.4 318.5 214.2 620.0 29.7 13.8 41.1 378.8 259.9 2029.3 590.1 319.2 81.4 48.2 30.5 105.2 631.8 246.5 3.4 27.8 534.9 1549.6 17.0 1760.1 342.5 581.4 238.0 ZMYM2 "FIM, MYM, RAMP, ZNF198" ENSG00000121741 "Zinc finger MYM-type containing 2" Q9UBW7 13 19958677-20091829 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 305.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031765 Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Endoplasmic reticulum" "HPA031765: AB_10601927" "unprognostic (2.96e-1)" "unprognostic (3.42e-3)" "unprognostic (1.85e-1)" "unprognostic (1.69e-1)" "unprognostic (7.71e-2)" "unprognostic (2.33e-1)" "unprognostic (2.66e-3)" "unprognostic (1.16e-1)" "unprognostic (6.78e-2)" "unprognostic (5.88e-2)" "unprognostic (4.60e-2)" "unprognostic (2.80e-2)" "unprognostic (6.65e-3)" "unprognostic (2.05e-1)" "unprognostic (8.74e-2)" "unprognostic (1.06e-1)" "prognostic favorable (6.07e-4)" 14.3 17.3 6.2 12.3 9.2 26.5 17.0 6.3 10.4 17.5 10.1 13.8 14.3 15.0 12.4 16.4 14.6 15.9 18.1 6.6 8.4 17.3 14.5 13.2 14.8 6.1 7.1 16.4 16.8 17.7 8.4 14.7 7.3 19.2 13.8 25.4 14.0 16.8 13.7 12.7 12.2 15.2 3.3 14.3 17.2 49.3 8.5 20.9 24.6 20.6 18.8 17.6 9.8 13.1 14.9 13.1 50.2 22.0 21.0 23.2 23.7 15.4 24.2 19.1 23.4 20.4 29.4 35.5 13.6 21.3 18.5 23.8 38.2 16.3 25.7 14.2 10.5 63.5 19.4 10.5 21.4 54.8 18.5 22.5 30.1 15.2 16.0 30.2 33.5 35.8 24.7 24.8 27.4 21.4 51.8 16.4 46.5 45.4 8.2 58.4 54.7 16.7 14.5 21.2 58.3 56.6 29.1 21.0 27.6 33.3 28.1 37.6 19.5 9.6 14.8 12.0 8.1 19.3 16.3 36.4 8.2 12.3 23.4 0.1 2.7 2.2 2.7 3.0 3.4 2.7 3.6 2.7 3.2 2.0 3.7 3.3 3.8 3.0 2.7 3.3 2.8 1.9 6.2 9.2 6.3 10.4 6.6 8.4 6.1 7.1 7.3 3.3 8.5 13.1 40.1 44.8 39.3 140.7 85.3 55.1 47.1 51.4 55.2 112.8 43.8 34.0 36.8 25.8 58.5 51.5 112.6 13.6 71.2 24.4 5.9 23.8 105.8 45.4 53.1 38.5 55.8 32.8 218.4 17.8 15.3 43.0 49.5 59.1 46.3 61.2 42.1 34.4 21.6 72.3 179.5 28.4 44.7 57.5 101.8 174.6 55.9 53.6 33.8 124.6 40.0 34.9 41.2 225.7 305.6 35.3 41.4 41.0 42.1 51.3 27.4 16.1 51.7 106.6 32.9 45.2 38.3 94.9 54.9 55.1 44.6 11.4 68.0 37.3 29.6 82.6 ZNF132 pHZ-12 ENSG00000131849 "Zinc finger protein 132" P52740 19 58432814-58440153 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.0;Cone photoreceptor cells: 4.2;Early spermatids: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA008726 Uncertain Approved "Vesicles,Intermediate filaments" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "Intermediate filaments" "HPA008726: AB_1080664" "unprognostic (4.86e-2)" "unprognostic (2.03e-1)" "unprognostic (6.79e-3)" "unprognostic (3.06e-2)" "unprognostic (8.16e-2)" "unprognostic (4.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.32e-3)" "unprognostic (5.00e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.92e-4)" "unprognostic (4.51e-1)" "prognostic favorable (7.26e-13)" "unprognostic (2.70e-1)" "unprognostic (7.65e-2)" "unprognostic (6.09e-2)" "unprognostic (3.72e-1)" 1.4 2.3 1.8 1.3 1.9 0.3 2.6 4.7 2.7 2.7 4.6 1.7 1.2 1.8 3.5 1.6 3.8 1.3 3.0 1.8 1.9 3.0 0.8 1.8 1.8 1.5 2.3 3.7 1.6 8.9 3.4 1.8 1.6 2.9 1.1 5.0 3.0 3.1 1.9 2.3 1.1 2.1 1.4 2.3 1.5 3.1 1.7 1.6 5.4 1.7 2.2 1.9 1.5 2.7 1.2 1.3 3.4 1.2 3.9 3.3 0.1 2.6 3.2 2.1 2.0 0.1 1.0 3.3 0.2 3.2 2.1 1.3 0.0 3.9 1.5 0.5 5.9 0.6 1.1 0.7 3.4 1.3 2.1 3.5 1.3 3.6 2.3 2.5 2.0 0.5 0.4 0.3 4.1 0.5 0.7 0.1 3.5 0.4 1.2 0.4 0.7 0.9 1.3 1.4 3.0 3.1 1.0 0.9 1.1 3.6 0.2 3.2 2.4 2.1 0.2 0.5 0.5 4.1 0.8 0.0 1.0 0.1 1.4 0.0 0.8 0.8 0.9 1.0 2.2 1.1 1.1 0.5 1.2 1.4 1.7 1.4 0.0 1.2 1.2 1.0 1.1 0.8 1.8 1.9 4.7 2.7 1.8 1.9 1.5 2.3 1.6 1.4 1.7 2.7 0.4 0.0 0.5 1.6 0.6 0.0 0.6 0.5 0.0 1.2 0.4 0.4 4.0 1.5 0.2 0.0 4.2 0.5 0.2 0.1 0.0 0.6 3.7 1.2 1.0 0.8 0.0 1.7 2.0 0.4 0.2 0.7 2.0 0.4 1.3 1.6 0.4 0.9 0.5 3.3 2.3 0.8 0.0 0.3 0.0 0.7 0.6 0.7 0.0 0.0 0.2 1.4 0.0 1.0 2.5 0.1 0.0 0.7 0.5 0.9 0.3 1.5 0.7 1.7 0.0 0.7 0.8 2.5 0.8 0.8 0.3 0.4 0.5 0.8 0.2 0.3 ZNF180 HHZ168 ENSG00000167384 "Zinc finger protein 180" Q9UJW8 19 44474428-44500524 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028979, HPA028980" Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA028979: AB_10600328, HPA028980: AB_10611524" "unprognostic (2.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.34e-3)" "unprognostic (1.37e-2)" "unprognostic (1.82e-1)" "unprognostic (7.13e-3)" "unprognostic (1.73e-1)" "unprognostic (2.16e-2)" "unprognostic (4.09e-3)" "unprognostic (1.33e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-2)" "unprognostic (6.49e-2)" "unprognostic (2.21e-1)" "unprognostic (2.02e-2)" "unprognostic (3.38e-3)" 2.8 2.8 1.7 2.4 1.8 2.7 4.5 2.3 2.2 3.2 2.4 2.9 2.4 3.5 2.6 2.7 4.1 1.6 2.4 1.8 1.8 2.9 3.3 3.0 3.2 1.8 2.0 4.7 3.3 8.1 2.4 2.7 1.9 5.2 3.4 4.7 2.4 3.0 2.6 3.0 3.0 3.2 1.8 3.2 3.1 2.8 1.8 3.9 4.5 2.2 4.0 2.7 2.8 2.2 7.0 2.0 9.1 6.5 2.1 3.9 5.5 4.0 4.3 6.3 7.4 3.6 0.9 0.6 3.1 5.5 4.5 2.2 5.5 8.0 7.8 8.0 3.3 7.7 1.6 2.7 2.0 11.7 4.8 3.8 3.3 3.8 4.8 5.8 4.4 3.4 3.7 5.6 4.4 1.3 6.2 4.1 6.0 6.5 4.4 3.7 4.9 5.2 6.1 11.4 7.5 6.4 7.1 6.8 3.3 5.8 3.6 9.8 3.5 10.8 4.3 1.4 5.7 1.5 5.7 3.2 2.4 5.0 5.6 2.1 1.1 2.3 1.1 0.6 1.6 1.8 1.7 2.0 1.7 1.7 1.9 1.8 0.3 1.7 1.2 0.4 4.6 1.3 1.7 1.8 2.3 2.2 1.8 1.8 1.8 2.0 1.9 1.8 1.8 2.2 3.4 6.4 1.5 4.2 4.3 2.5 2.2 2.4 4.0 6.7 3.2 2.4 4.5 2.8 4.1 1.8 4.2 5.5 4.2 3.5 7.9 4.2 5.8 3.0 4.7 2.8 4.2 8.2 5.7 4.2 4.0 3.5 4.1 2.9 1.3 5.7 5.3 3.7 3.4 1.7 5.8 4.9 6.1 4.6 1.1 1.3 2.8 2.6 5.4 8.4 5.4 6.0 7.2 6.6 9.0 3.9 5.7 4.5 1.7 2.2 4.3 3.5 4.3 4.4 6.6 4.3 3.5 2.7 4.6 2.5 1.3 3.1 4.0 3.5 4.0 1.7 ZNF300 ENSG00000145908 "Zinc finger protein 300" Q96RE9 5 150894392-150904983 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 13.3;Granulosa cells: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 36.1" "Low region specificity" "Detected in all" "HPA028975, HPA051777" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nucleoli, Nucleoli rim, Nuclear bodies" "HPA028975: AB_2672851, HPA051777: AB_2681606" "unprognostic (5.06e-2)" "unprognostic (1.05e-2)" "unprognostic (8.41e-2)" "unprognostic (2.31e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (1.15e-1)" "unprognostic (6.23e-3)" "unprognostic (4.21e-2)" "unprognostic (3.23e-1)" "unprognostic (8.62e-2)" "unprognostic (6.85e-3)" "prognostic unfavorable (3.21e-6)" "unprognostic (3.62e-3)" "unprognostic (2.99e-1)" "unprognostic (3.46e-1)" "unprognostic (1.50e-2)" 3.6 1.0 2.3 2.6 3.2 2.7 4.5 3.8 2.8 6.5 2.3 3.6 2.7 7.4 2.3 5.1 4.4 3.3 3.2 2.3 2.9 7.4 1.2 2.4 3.0 3.0 3.1 10.2 5.5 0.8 2.4 1.5 3.1 5.4 2.7 9.1 2.8 2.3 0.9 4.4 3.8 4.0 2.6 3.9 4.7 6.4 2.9 2.8 6.9 1.5 2.9 4.5 4.9 3.5 2.1 4.7 28.2 0.0 2.4 5.8 0.0 7.1 5.6 6.1 8.7 2.4 3.5 0.0 6.1 5.9 18.3 4.2 0.0 16.2 9.5 0.0 9.3 0.0 36.1 3.9 5.0 0.2 0.1 8.9 5.0 12.7 14.7 8.6 10.4 0.1 0.0 15.1 6.1 0.0 0.0 1.5 27.2 0.0 0.0 0.0 4.1 8.5 4.4 5.3 15.9 26.2 16.7 14.3 9.8 17.1 9.4 0.0 4.6 8.1 3.4 5.9 12.9 0.5 0.2 0.0 0.8 0.1 17.1 0.0 0.1 0.3 0.1 0.4 0.0 0.2 0.2 0.0 0.3 1.3 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 2.3 3.2 3.8 2.8 2.3 2.9 3.0 3.1 3.1 2.6 2.9 3.5 2.0 0.0 0.5 0.3 1.8 1.5 3.1 2.3 7.4 4.0 2.3 1.7 0.6 1.5 2.7 7.3 0.0 0.7 1.9 0.3 1.9 2.5 3.2 1.8 5.3 2.3 3.0 4.0 0.8 1.6 2.2 3.8 13.3 1.9 0.0 11.5 1.8 0.2 0.5 0.0 1.9 1.4 2.0 1.0 1.2 0.9 2.5 0.8 0.0 5.6 1.5 3.3 3.1 5.5 6.7 1.8 0.1 1.2 0.3 2.0 0.6 1.8 0.8 4.3 6.6 4.1 2.8 7.2 3.7 5.9 2.3 0.8 1.2 2.7 1.8 3.0 ZNF331 "RITA, ZNF361, ZNF463" ENSG00000130844 "Zinc finger protein 331" Q9NQX6 19 53519527-53580269 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 284.5;dendritic cells: 298.4;granulocytes: 241.9;Langerhans cells: 245.5;Macrophages: 241.4;T-cells: 303.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 79.7;RT4: 63.4" "Low region specificity" "Detected in all" HPA063157 Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA063157: AB_2684951" "unprognostic (2.19e-1)" "unprognostic (1.79e-1)" "unprognostic (5.18e-2)" "unprognostic (1.55e-2)" "unprognostic (4.24e-1)" "unprognostic (8.16e-2)" "unprognostic (7.62e-3)" "unprognostic (3.25e-2)" "unprognostic (1.84e-2)" "unprognostic (4.40e-2)" "unprognostic (5.68e-3)" "unprognostic (2.69e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (6.74e-2)" 52.6 124.7 14.3 18.5 13.5 46.3 19.2 55.9 25.1 22.6 23.6 14.8 4.8 20.2 10.7 7.5 46.6 22.6 39.0 13.7 21.2 13.7 12.3 43.4 10.3 24.1 23.0 119.4 21.0 17.0 74.7 54.5 17.8 24.3 8.4 41.2 11.0 22.4 18.8 14.4 10.8 14.2 11.6 10.6 15.3 20.0 22.6 12.2 16.6 9.3 8.7 28.8 16.5 14.7 0.2 11.3 22.5 26.0 15.0 10.7 38.3 16.2 13.7 12.0 21.4 11.8 5.7 7.9 4.2 9.4 5.4 6.6 16.4 12.1 21.4 0.1 79.7 11.8 18.8 7.5 10.9 6.8 15.4 12.4 6.9 13.2 4.8 6.2 5.6 13.9 0.5 3.0 11.4 7.6 16.5 15.1 9.5 0.2 15.5 20.2 13.5 9.6 5.9 63.4 14.3 15.7 7.1 18.8 4.5 43.2 4.1 6.7 5.6 17.0 15.1 10.0 11.1 37.7 28.2 17.8 0.2 1.0 13.9 0.8 5.7 8.2 9.6 4.7 15.2 8.9 10.5 9.7 4.3 10.3 15.6 10.2 0.7 6.1 9.8 4.8 11.7 5.9 14.3 13.5 55.9 25.1 13.7 21.2 24.1 23.0 17.8 11.6 22.6 14.7 37.4 19.2 56.2 13.1 284.5 44.7 21.1 10.9 95.6 56.2 28.6 44.7 20.5 35.8 15.2 77.3 29.2 38.2 298.4 1.6 9.8 4.0 125.7 51.0 18.9 36.8 23.4 7.4 36.3 4.0 33.7 96.7 52.5 79.3 241.9 14.5 13.6 3.8 62.1 30.3 39.9 4.8 14.2 46.8 245.5 84.8 24.2 241.4 46.2 15.0 5.9 33.8 11.3 17.6 24.9 2.4 2.7 19.5 141.7 15.9 3.9 4.4 12.4 38.3 0.0 44.0 151.4 39.2 23.5 15.8 50.6 44.5 303.9 14.0 5.2 12.3 ZNF384 "CAGH1A, CIZ, NMP4, NP, TNRC1" ENSG00000126746 "Zinc finger protein 384" Q8TF68 12 6666477-6689572 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004051 Supported Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA004051: AB_1859228" "unprognostic (1.90e-1)" "unprognostic (5.11e-3)" "unprognostic (1.76e-1)" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (3.04e-2)" "unprognostic (1.87e-2)" "unprognostic (9.94e-2)" "unprognostic (1.35e-2)" "unprognostic (2.57e-2)" "unprognostic (3.51e-2)" "unprognostic (4.25e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.22e-1)" "unprognostic (2.06e-1)" "unprognostic (8.13e-2)" 31.4 33.2 21.9 36.2 23.2 59.9 30.7 26.9 26.4 39.8 22.9 35.1 35.1 40.6 25.1 27.9 35.8 26.1 25.9 22.5 23.8 28.9 26.3 28.6 36.0 23.5 22.3 46.3 29.8 34.7 32.6 32.5 22.3 31.9 32.7 30.2 29.9 30.0 36.7 32.1 36.8 37.8 20.8 40.2 30.9 31.7 22.8 46.7 38.4 32.3 37.6 36.7 30.8 25.4 35.4 66.2 79.9 53.7 55.2 38.9 107.1 50.0 46.4 47.3 50.3 73.3 73.6 82.9 18.5 56.4 68.5 46.6 59.8 45.9 53.6 150.8 54.0 94.9 93.0 38.6 38.9 91.2 67.5 43.0 43.6 58.3 90.1 88.9 41.5 57.4 50.6 27.9 52.4 54.8 82.6 58.3 155.0 64.1 28.7 81.0 85.4 32.2 41.9 93.6 24.8 80.4 51.8 68.4 44.1 133.5 18.0 74.5 51.9 51.6 71.4 40.9 59.6 38.5 39.6 149.9 51.0 32.4 60.0 3.7 8.5 15.4 16.4 9.8 13.4 9.7 10.7 13.4 11.5 8.0 10.2 11.6 14.4 17.0 15.3 7.6 14.5 8.3 21.9 23.2 26.9 26.4 22.5 23.8 23.5 22.3 22.3 20.8 22.8 25.4 19.2 0.0 8.7 17.3 12.5 7.9 2.6 4.4 12.0 6.0 11.1 11.9 2.6 10.0 4.7 1.8 10.4 6.7 17.9 16.5 0.0 4.6 4.3 10.2 12.9 10.7 3.6 8.0 10.3 5.0 6.8 8.2 12.8 13.5 5.7 14.7 8.9 8.3 7.0 0.0 10.4 11.8 2.0 16.6 6.0 2.7 8.4 8.6 5.4 6.5 9.9 6.1 7.2 9.0 11.8 6.8 14.4 8.6 11.4 4.8 10.6 4.3 5.6 7.8 0.0 9.3 9.3 7.1 6.5 10.7 9.8 7.3 13.2 9.0 13.4 4.6 ZNF471 "KIAA1396, Z1971, Zfp78" ENSG00000196263 "Zinc finger protein 471" Q9BX82 19 56507850-56530221 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Oligodendrocytes: 32.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HSkMC: 8.5;hTERT-RPE1: 12.6;SuSa: 9.0" "Low region specificity" "Detected in all" HPA066695 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA066695: AB_2685704" "unprognostic (2.89e-2)" "unprognostic (2.79e-4)" "unprognostic (1.58e-1)" "unprognostic (2.90e-2)" "unprognostic (2.22e-1)" "unprognostic (2.42e-3)" "unprognostic (1.45e-1)" "unprognostic (8.44e-2)" "unprognostic (1.01e-2)" "unprognostic (4.14e-2)" "unprognostic (4.47e-4)" "unprognostic (9.36e-2)" "prognostic favorable (2.37e-4)" "unprognostic (3.84e-3)" "unprognostic (1.08e-1)" "unprognostic (7.89e-2)" "unprognostic (3.44e-3)" 5.7 6.3 13.6 2.4 16.1 2.8 7.1 14.0 14.8 10.3 7.4 8.9 1.8 13.3 15.9 4.8 10.5 6.8 5.7 13.4 16.6 5.3 2.4 5.6 3.0 14.8 13.1 22.4 3.6 10.4 8.4 6.2 13.7 8.2 4.5 28.5 6.0 7.5 4.9 9.5 3.2 7.9 9.9 4.4 4.5 8.5 14.7 2.7 9.8 6.3 2.0 7.0 7.6 25.5 0.4 0.5 4.8 0.6 4.1 4.5 0.5 4.5 1.6 2.1 1.8 0.6 0.6 0.6 3.0 5.0 4.0 0.3 0.6 0.4 2.0 1.0 1.8 3.6 1.3 0.5 4.0 1.0 3.1 8.5 1.6 2.6 0.2 12.6 0.2 0.5 1.1 1.3 2.3 0.5 0.4 0.6 1.1 0.3 1.9 0.4 3.1 0.4 3.5 3.7 0.6 2.9 0.4 0.1 0.2 9.0 0.6 0.7 0.7 7.6 3.2 0.6 3.5 1.0 1.1 0.3 0.6 0.5 0.4 1.5 0.4 0.3 0.6 0.3 0.4 0.4 0.5 0.4 0.2 0.9 0.5 0.7 1.8 1.0 0.4 0.5 0.3 0.1 13.6 16.1 14.0 14.8 13.4 16.6 14.8 13.1 13.7 9.9 14.7 25.5 5.7 19.2 18.4 24.8 0.6 0.6 2.4 1.6 2.2 11.2 4.1 4.6 10.9 2.8 7.8 5.5 6.2 1.0 1.7 0.9 3.9 2.1 10.2 8.2 5.9 6.0 1.2 0.4 15.0 1.0 0.4 4.6 1.5 6.7 2.5 8.4 5.0 0.8 0.5 6.7 14.4 0.9 0.0 0.6 0.3 3.6 5.0 1.9 1.8 5.6 0.6 7.9 2.1 20.1 32.3 0.7 0.2 7.2 0.0 2.5 0.5 1.6 11.9 9.5 6.6 7.9 6.7 9.9 8.2 1.6 0.6 0.8 0.9 3.6 1.2 1.6 ZNF483 "KIAA1962, ZKSCAN16, ZSCAN48" ENSG00000173258 "Zinc finger protein 483" Q8TF39 9 111525159-111577844 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 46.5;Excitatory neurons: 118.2;Inhibitory neurons: 122.4;Oligodendrocyte precursor cells: 54.3;Oligodendrocytes: 86.8" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055041 Approved Nucleoli NA NA "Cluster 32: T-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA055041: AB_2682681" "unprognostic (4.33e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" "unprognostic (2.34e-1)" "unprognostic (4.11e-2)" "unprognostic (5.95e-3)" "unprognostic (9.18e-5)" "unprognostic (2.02e-1)" "unprognostic (9.50e-2)" "unprognostic (4.44e-3)" "unprognostic (5.49e-2)" "unprognostic (5.19e-4)" "unprognostic (7.19e-3)" "unprognostic (1.74e-1)" "unprognostic (4.30e-2)" "unprognostic (6.17e-2)" 1.1 6.0 23.0 0.7 23.3 3.6 2.7 42.0 20.6 2.4 0.7 1.6 0.9 5.0 8.3 0.9 3.0 2.2 2.1 20.6 39.4 2.2 0.8 1.6 1.5 3.4 14.6 5.6 1.8 3.9 5.9 0.5 10.3 3.6 0.8 11.7 1.5 3.8 1.4 1.7 1.2 2.3 5.5 2.3 1.4 5.2 32.2 1.0 6.0 0.7 1.1 1.3 1.7 14.8 0.2 2.0 2.1 3.4 0.5 0.5 0.6 0.4 1.0 2.0 1.7 0.2 0.9 0.3 0.3 0.8 1.5 0.7 1.1 0.9 1.2 0.1 1.3 1.0 3.2 2.3 0.6 0.4 0.2 0.8 0.5 1.1 0.5 1.7 1.8 1.4 0.8 0.5 0.5 2.2 0.1 0.4 9.7 1.3 0.7 0.2 2.9 0.3 1.1 0.8 4.8 2.2 1.0 0.5 0.4 2.1 1.2 0.3 0.5 0.6 1.0 1.1 1.5 0.4 1.3 0.2 0.8 0.3 0.3 3.1 0.4 0.3 2.7 0.2 1.6 0.8 1.7 1.3 0.1 1.2 3.3 3.6 1.5 1.1 0.4 0.5 1.1 0.8 23.0 23.3 42.0 20.6 20.6 39.4 3.4 14.6 10.3 5.5 32.2 14.8 1.6 0.0 6.3 33.0 1.4 0.8 6.3 1.5 2.2 46.5 2.0 7.6 4.0 1.5 4.0 7.3 20.9 1.1 3.0 0.2 5.9 1.0 20.3 2.6 1.9 2.0 3.0 0.0 118.2 2.0 0.5 6.1 1.5 3.5 0.0 4.9 1.4 2.1 0.3 35.3 122.4 0.1 0.0 0.9 1.9 8.6 4.7 0.6 1.8 13.1 0.4 19.1 5.2 54.3 86.8 1.0 1.1 10.1 0.2 4.2 0.8 0.2 1.6 26.8 6.6 5.5 3.5 11.0 4.1 0.6 1.4 0.7 2.6 6.3 0.2 3.7 ZNF521 "EHZF, Evi3" ENSG00000198795 "Zinc finger protein 521" Q96K83 18 25061924-25352190 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 95.9" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Microglial cells: 53.4;Oligodendrocyte precursor cells: 221.7;Oligodendrocytes: 104.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 95.9" "Group enriched" "Detected in some" 6 "basophil: 11.4;plasmacytoid DC: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 8.8;granulocytes: 11.4" "Cell line enhanced" "Detected in many" "AF22: 67.6;fHDF/TERT166: 32.7;HUVEC TERT2: 46.9;THP-1: 38.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 49.7" "HPA023056, HPA023849" Enhanced Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA023056: AB_1859315, HPA023849: AB_1859316" "unprognostic (8.80e-3)" "unprognostic (9.68e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (5.43e-2)" "unprognostic (3.73e-3)" "unprognostic (1.52e-3)" "unprognostic (6.17e-2)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (8.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.19e-3)" "unprognostic (1.16e-3)" "unprognostic (2.43e-1)" "unprognostic (2.52e-3)" "unprognostic (7.82e-4)" 13.4 11.9 8.8 3.1 10.5 2.3 11.4 95.9 9.5 10.8 29.9 4.7 1.7 15.3 4.3 3.9 9.0 10.6 9.1 6.0 14.7 3.2 1.2 6.3 3.8 17.4 14.3 20.5 1.2 1.1 7.6 8.6 21.2 2.6 3.6 5.7 9.0 3.0 3.7 6.1 4.4 13.6 12.4 21.0 2.7 3.6 10.8 4.3 6.8 6.0 2.8 5.8 6.8 13.5 0.1 0.0 67.6 0.1 10.6 18.4 0.2 10.0 14.3 3.4 2.1 0.0 0.1 0.0 0.0 32.7 0.0 0.3 0.0 0.0 2.8 0.0 4.0 14.0 0.6 0.5 1.9 0.0 20.2 23.0 0.0 0.3 0.0 0.0 46.9 16.4 0.3 0.1 6.0 0.0 9.2 0.0 4.7 0.0 0.0 0.0 15.2 1.1 0.0 0.0 8.7 5.5 0.8 0.0 0.0 6.1 0.0 38.9 26.9 26.5 2.0 8.0 1.5 0.1 0.0 0.3 10.0 0.0 22.2 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 8.8 0.0 0.1 8.8 10.5 95.9 9.5 6.0 14.7 17.4 14.3 21.2 12.4 10.8 13.5 19.0 0.0 3.0 170.1 0.3 3.7 0.1 0.0 1.2 42.4 8.0 10.9 11.9 0.0 0.6 0.0 2.1 0.1 1.7 0.0 0.0 0.0 2.1 0.5 3.3 28.6 1.2 13.9 16.5 0.0 0.0 21.4 0.0 0.2 13.3 4.7 20.3 0.0 0.1 15.2 22.7 0.1 0.0 0.6 5.5 3.3 9.9 0.9 14.2 53.4 0.1 0.7 0.0 221.7 104.6 0.0 0.0 7.9 0.1 0.2 0.0 4.0 1.5 3.0 0.0 13.7 6.0 0.1 6.1 0.8 4.4 0.1 0.8 17.2 0.0 0.2 ZNF620 MGC50836 ENSG00000177842 "Zinc finger protein 620" Q6ZNG0 3 40477131-40518736 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA031452, HPA059383" Uncertain Approved Centrosome NA NA "Cluster 44: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" Centrosome "HPA031452: AB_10603939, HPA059383: AB_2732636" "unprognostic (1.42e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-2)" "unprognostic (5.62e-2)" "unprognostic (1.86e-1)" "unprognostic (3.04e-3)" "unprognostic (2.15e-2)" "unprognostic (7.73e-2)" "unprognostic (3.78e-2)" "unprognostic (1.71e-2)" "unprognostic (4.09e-2)" "unprognostic (1.21e-5)" "unprognostic (1.28e-1)" "unprognostic (4.78e-1)" "unprognostic (2.61e-2)" "unprognostic (9.19e-4)" 1.4 1.9 2.1 1.0 3.3 3.2 2.0 4.6 2.4 1.3 2.8 1.8 1.7 1.3 1.6 1.1 1.9 1.1 1.7 1.7 2.4 2.4 1.4 2.2 1.3 2.6 2.6 1.5 2.5 2.7 2.5 2.3 2.4 1.8 2.1 4.3 1.0 1.9 2.6 0.7 1.5 1.6 2.2 1.8 2.7 1.1 2.7 1.6 3.4 2.3 1.0 1.4 0.9 3.5 2.4 3.1 8.8 3.3 0.7 0.9 3.6 0.6 1.0 3.8 6.0 9.0 5.2 0.0 2.7 0.5 3.5 0.6 13.3 1.3 3.1 8.0 10.4 6.6 9.8 4.9 1.5 2.4 1.0 0.6 0.9 2.6 1.2 1.0 3.0 0.1 3.5 0.8 0.5 4.5 0.5 2.0 10.4 5.0 2.0 3.6 3.5 1.2 3.9 8.7 10.4 8.0 0.7 6.3 4.2 7.9 8.1 2.4 2.0 0.4 5.8 0.8 2.9 1.3 2.3 0.1 1.4 1.2 1.5 7.7 0.5 1.0 2.1 0.9 2.4 0.4 0.8 2.0 0.5 1.6 1.6 2.2 0.6 3.0 0.3 1.2 3.5 0.9 2.1 3.3 4.6 2.4 1.7 2.4 2.6 2.6 2.4 2.2 2.7 3.5 5.4 6.4 4.1 2.6 1.7 0.5 3.4 1.6 0.6 10.5 3.3 2.9 2.1 4.3 3.2 0.0 4.2 8.5 3.6 2.3 5.9 6.1 0.1 4.3 2.0 5.4 9.0 8.6 1.6 2.9 1.8 2.1 3.1 9.2 7.0 7.8 5.0 2.1 1.4 3.3 2.2 4.2 8.2 1.9 1.2 0.7 0.3 1.6 0.0 0.0 11.0 9.0 7.2 3.0 6.2 2.2 4.8 0.4 0.5 2.8 2.3 3.5 2.1 11.6 0.0 4.5 4.6 7.8 6.7 0.8 0.1 1.9 2.7 5.0 4.3 1.4 ZNF750 "FLJ13841, Zfp750" ENSG00000141579 "Zinc finger protein 750" Q32MQ0 17 82829434-82840022 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 139.0;vagina: 51.7" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 33.3;Squamous epithelial cells: 156.8;Suprabasal keratinocytes: 41.1;Syncytiotrophoblasts: 68.1;Urothelial cells: 51.3" "Cancer enhanced" "Detected in many" "cervical cancer: 20.5;head and neck cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.3;hTCEpi: 7.2;MCF7: 5.4;SK-BR-3: 14.0" "Not detected" "Not detected" "HPA021573, HPA023012" Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA021573: AB_1859438, HPA023012: AB_1859439" "unprognostic (3.46e-3)" "unprognostic (1.94e-2)" "unprognostic (7.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (9.73e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-3)" "unprognostic (1.34e-1)" "unprognostic (4.33e-2)" "unprognostic (6.30e-3)" "unprognostic (1.23e-2)" "unprognostic (5.30e-3)" "unprognostic (3.04e-2)" "unprognostic (5.94e-2)" "unprognostic (2.04e-1)" "unprognostic (4.25e-2)" 0.5 0.1 0.8 0.0 1.2 0.1 5.1 0.5 0.9 25.0 0.0 0.1 0.1 0.2 4.1 96.1 0.6 0.2 0.6 0.6 0.2 0.4 0.1 2.0 0.0 1.0 0.3 0.1 0.2 2.2 2.9 3.9 1.0 3.3 0.0 0.0 33.6 2.7 12.0 139.0 0.1 0.0 0.2 0.1 0.2 0.4 0.6 5.1 3.5 0.0 14.7 4.9 51.7 2.3 0.1 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.3 1.2 1.0 0.0 14.0 0.0 1.7 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.5 0.9 0.6 0.2 1.0 0.3 1.0 0.2 0.6 2.3 0.6 0.0 8.2 0.0 0.0 5.2 14.3 19.6 9.1 0.0 7.4 5.0 0.4 0.0 21.2 0.0 0.0 23.1 0.0 0.0 0.0 0.0 2.4 27.1 3.3 0.9 0.0 0.0 0.4 0.0 1.9 0.3 0.0 33.3 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.0 10.2 0.0 0.3 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 7.6 0.0 0.1 14.2 0.0 0.0 0.1 1.5 0.0 0.2 156.8 41.1 68.1 0.2 0.0 0.0 51.3 ZNF814 ENSG00000204514 "Zinc finger protein 814" B7Z6K7 19 57848731-57889074 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 32.5;U-266/84: 33.4" "HPA043800, HPA053762, HPA072145" Approved Uncertain Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA043800: AB_2678675, HPA053762: AB_2682252, HPA072145: " "unprognostic (3.74e-2)" "unprognostic (1.24e-1)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (6.01e-2)" "unprognostic (2.12e-2)" "unprognostic (1.03e-1)" "unprognostic (4.69e-2)" "unprognostic (6.78e-4)" "unprognostic (5.05e-3)" "unprognostic (2.41e-4)" "unprognostic (1.56e-2)" "unprognostic (4.99e-4)" "unprognostic (3.94e-1)" "unprognostic (2.33e-1)" "unprognostic (1.08e-1)" "unprognostic (1.54e-5)" 6.4 14.5 9.2 4.5 7.8 10.4 8.1 24.8 8.3 5.5 7.3 7.6 6.6 5.2 6.9 5.2 8.5 4.5 12.9 9.2 5.2 14.5 13.4 6.3 8.7 6.3 5.2 7.4 7.2 9.7 14.2 4.9 5.7 12.6 4.8 13.8 8.7 5.5 10.0 9.5 9.2 4.0 1.2 13.0 5.4 11.2 6.6 9.5 14.7 5.7 8.1 6.3 5.4 7.1 1.6 4.0 11.6 16.6 1.2 1.1 3.0 4.1 2.7 4.4 0.6 2.0 1.6 8.9 2.7 3.8 4.5 1.3 0.7 8.8 5.4 1.6 7.9 6.6 7.0 2.4 4.8 7.8 8.2 7.3 7.9 1.6 1.7 7.8 1.1 3.6 1.8 3.6 7.3 1.7 25.2 3.6 32.5 0.9 5.1 3.1 1.3 15.6 3.8 6.2 4.7 11.8 1.4 3.2 6.1 23.5 8.0 2.5 2.5 10.3 3.5 2.4 2.2 10.1 33.4 22.5 2.6 4.3 12.9 4.6 8.2 9.7 5.4 9.7 14.0 37.4 14.2 11.7 11.9 38.7 22.4 18.5 5.4 24.8 6.0 27.9 4.2 7.4 9.2 7.8 24.8 8.3 9.2 5.2 6.3 5.2 5.7 1.2 6.6 7.1 6.2 0.0 1.5 4.6 15.6 6.8 10.5 7.3 4.0 22.7 11.5 9.8 12.9 21.5 10.1 12.9 47.9 13.2 10.8 5.0 17.6 8.0 46.5 13.9 6.6 7.6 4.9 5.9 10.9 1.4 18.6 5.5 6.1 20.4 16.5 12.6 14.6 15.3 13.0 20.2 12.3 8.7 14.2 2.8 7.9 19.5 4.1 6.5 10.6 4.7 5.9 9.4 13.4 7.5 10.1 1.7 17.8 7.2 5.9 8.4 10.5 44.0 8.4 35.9 19.7 5.7 6.6 14.1 10.9 3.5 13.1 11.6 9.2 8.9 22.1 12.6 ZNF844 FLJ14959 ENSG00000223547 "Zinc finger protein 844" Q08AG5 19 12064731-12081565 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/84: 11.7" HPA046982 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA046982: AB_10964399" "unprognostic (2.07e-1)" "unprognostic (1.50e-2)" "unprognostic (1.75e-1)" "unprognostic (8.95e-2)" "unprognostic (2.92e-3)" "unprognostic (9.68e-3)" "unprognostic (1.93e-1)" "unprognostic (1.87e-2)" "unprognostic (1.86e-2)" "unprognostic (5.86e-2)" "unprognostic (2.47e-2)" "unprognostic (6.74e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.99e-1)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (3.63e-2)" 3.4 2.0 3.1 1.8 4.4 3.8 4.6 7.5 3.3 3.9 4.3 4.0 1.8 3.9 3.8 2.9 4.9 1.5 5.3 3.2 3.2 7.0 2.9 2.6 2.0 4.0 3.7 8.5 3.3 7.4 3.2 2.5 3.5 3.7 2.9 11.9 5.1 3.4 3.4 3.6 2.6 2.8 3.2 2.8 3.0 3.7 3.8 1.6 7.7 4.6 1.8 4.2 3.5 6.8 0.0 0.1 1.3 3.4 2.5 1.5 1.3 1.8 0.3 1.6 0.9 3.4 0.6 2.0 2.2 1.7 1.4 1.0 0.0 0.3 1.2 0.1 0.1 4.2 0.3 0.8 2.2 0.2 3.0 1.9 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.3 1.0 0.1 1.6 0.8 1.8 0.0 0.1 0.2 4.5 0.5 0.9 0.1 1.4 1.0 0.0 1.5 0.6 2.4 3.6 0.1 0.1 0.6 1.5 1.9 1.9 3.8 11.7 0.2 0.1 0.2 0.3 3.2 0.5 1.2 0.4 0.8 0.2 0.6 0.2 0.2 0.2 0.6 0.4 0.4 1.9 0.7 0.4 0.2 0.1 0.3 3.1 4.4 7.5 3.3 3.2 3.2 4.0 3.7 3.5 3.2 3.8 6.8 20.0 16.0 11.5 4.2 16.0 2.4 5.6 2.2 10.8 19.2 16.2 16.3 31.5 14.3 11.1 3.7 33.3 4.1 6.8 14.0 5.9 3.9 2.8 9.9 15.5 10.2 14.4 2.1 1.7 3.3 3.4 13.4 17.3 13.5 19.6 11.6 7.5 4.2 6.4 25.2 0.6 8.4 2.0 6.2 4.0 2.8 3.7 9.7 7.2 3.7 3.3 12.5 7.2 7.1 3.6 1.4 7.6 6.8 6.4 6.9 5.9 7.4 7.7 60.6 0.0 31.5 12.6 19.2 8.7 14.0 3.3 5.2 5.8 3.1 6.9 5.4 ZNF91 "HPF7, HTF10" ENSG00000167232 "Zinc finger protein 91" Q05481 19 23304991-23395471 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 434.3;Late spermatids: 630.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.53e-1)" "unprognostic (3.60e-2)" "unprognostic (4.94e-2)" "unprognostic (1.18e-2)" "unprognostic (3.32e-3)" "unprognostic (5.62e-2)" "unprognostic (1.99e-3)" "unprognostic (5.85e-2)" "unprognostic (9.85e-4)" "unprognostic (6.74e-3)" "unprognostic (3.02e-2)" "unprognostic (4.47e-2)" "prognostic favorable (7.58e-4)" "unprognostic (7.38e-3)" "unprognostic (1.09e-1)" "unprognostic (2.21e-2)" "prognostic favorable (3.48e-4)" 3.9 4.9 3.1 4.9 10.1 2.9 9.2 29.2 10.2 6.5 0.0 10.3 12.2 6.8 7.7 5.6 6.4 4.2 5.6 8.5 0.0 7.4 5.5 4.6 7.9 5.0 4.0 9.3 4.3 9.9 6.4 6.6 2.7 7.5 10.6 14.6 6.7 4.5 9.0 6.3 13.5 4.5 0.0 7.0 7.1 3.4 7.4 8.1 10.4 9.6 6.7 5.5 5.6 7.9 5.1 0.8 16.1 7.7 4.6 7.3 8.7 3.6 6.1 9.4 11.6 4.2 5.0 0.2 7.5 4.7 3.5 6.2 12.9 3.9 11.7 0.5 12.3 2.3 4.2 3.1 3.6 0.2 4.0 6.2 7.6 7.5 8.8 8.5 3.3 10.2 8.1 1.1 7.2 3.1 15.5 5.9 11.3 0.1 4.5 11.5 10.2 8.8 5.7 12.9 9.8 7.7 0.3 0.3 4.1 10.9 4.8 9.8 4.7 2.7 1.7 4.4 7.0 0.4 4.3 15.2 0.1 0.4 1.5 4.5 1.8 2.1 5.9 1.5 5.2 5.3 6.9 6.3 2.1 6.9 9.7 7.9 3.7 4.6 3.2 4.9 4.4 3.0 3.1 10.1 29.2 10.2 8.5 0.0 5.0 4.0 2.7 0.0 7.4 7.9 28.7 41.7 43.5 24.5 29.7 10.5 29.5 11.8 20.5 128.9 35.3 32.1 139.0 24.3 24.8 38.6 83.4 17.8 31.1 61.9 37.2 16.2 434.3 22.2 26.7 24.7 36.7 9.2 47.7 13.5 21.0 25.8 27.0 24.1 22.2 60.4 23.9 15.7 11.3 138.0 51.7 45.8 4.1 13.2 12.4 630.5 32.0 15.8 10.6 27.2 10.9 95.9 45.3 46.8 45.2 17.2 47.2 25.9 17.5 27.7 60.7 27.6 26.8 106.9 26.3 37.5 20.8 24.4 31.9 14.8 12.4 81.3 29.7 35.3 45.6 33.6 ZRANB3 "AH2, DKFZP434B1727" ENSG00000121988 "Zinc finger RANBP2-type containing 3" Q5FWF4 2 135136916-135531218 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Astrocytes: 34.9;Excitatory neurons: 69.4;Inhibitory neurons: 46.2;Oligodendrocytes: 67.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035234 Supported Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA035234: AB_2674530" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (1.01e-1)" "unprognostic (2.52e-3)" "unprognostic (4.09e-1)" "unprognostic (1.33e-1)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (3.53e-3)" "unprognostic (1.74e-1)" "unprognostic (3.58e-2)" "unprognostic (4.68e-2)" "unprognostic (2.77e-4)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (2.00e-2)" "unprognostic (9.88e-2)" 0.8 1.4 0.5 0.9 0.7 1.1 0.8 0.2 0.8 1.0 0.2 0.7 0.5 0.9 0.5 0.7 0.9 0.7 0.9 0.6 0.3 0.7 1.1 0.6 0.6 0.1 0.1 1.5 1.3 0.6 1.4 0.5 0.2 0.9 0.4 1.5 0.7 0.5 2.0 0.8 0.6 0.4 0.1 0.8 0.7 3.2 0.3 0.8 1.0 0.6 0.4 0.8 0.8 0.7 0.9 0.9 1.7 1.1 0.8 1.5 1.5 1.3 0.9 0.9 1.1 1.5 0.7 2.8 1.3 1.0 0.6 0.9 2.4 1.1 1.6 2.5 1.8 3.2 0.4 3.5 0.6 2.5 0.6 1.3 1.0 1.3 3.2 1.5 1.3 1.6 3.1 1.3 0.7 1.3 1.5 1.4 1.1 0.8 1.1 1.8 1.3 1.0 1.3 0.6 1.8 2.3 1.1 0.5 0.9 1.6 0.9 1.1 1.0 0.7 0.6 0.4 0.8 1.1 1.4 2.6 1.0 1.7 1.0 0.1 0.1 0.1 0.1 0.0 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.5 0.7 0.2 0.8 0.6 0.3 0.1 0.1 0.2 0.1 0.3 0.7 1.7 3.2 1.5 34.9 7.3 1.3 4.5 4.5 8.0 5.8 2.8 2.3 3.3 2.8 4.3 0.0 8.4 5.7 2.0 0.5 0.0 2.0 16.9 3.2 5.0 1.9 1.8 10.1 69.4 0.9 8.3 4.7 1.5 3.5 0.0 9.1 1.8 8.9 2.5 5.0 46.2 1.2 4.1 0.8 1.5 4.5 3.1 2.3 0.0 26.2 2.9 2.7 2.1 24.6 67.0 1.4 1.7 2.2 4.7 2.1 0.4 4.5 1.6 7.5 0.0 8.3 3.4 14.1 10.3 4.8 2.3 3.8 3.9 10.8 2.6 3.0 ZRSR2 "U2AF1-RS2, U2AF1L2, URP, ZC3H22" ENSG00000169249 "Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2" Q15696 X 15790472-15823260 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (7.96e-4)" "unprognostic (1.54e-2)" "unprognostic (7.31e-2)" "prognostic favorable (8.50e-5)" "unprognostic (8.08e-2)" "unprognostic (1.69e-1)" "unprognostic (6.14e-3)" "unprognostic (5.72e-3)" "unprognostic (8.46e-2)" "unprognostic (3.47e-3)" "unprognostic (6.90e-2)" "unprognostic (2.85e-2)" "prognostic unfavorable (4.87e-5)" "unprognostic (8.14e-2)" "unprognostic (3.04e-1)" "unprognostic (1.65e-2)" "prognostic favorable (2.97e-4)" 15.2 12.1 25.7 17.3 25.1 42.7 16.2 28.8 36.1 24.3 26.5 22.9 11.0 21.3 20.2 13.4 20.2 10.2 17.2 24.4 27.5 16.2 13.3 20.1 29.0 25.9 24.9 22.2 14.3 13.0 24.1 10.8 24.9 18.1 12.5 22.2 13.9 11.9 20.4 15.4 19.8 17.0 23.2 31.8 14.8 5.6 26.0 21.9 17.4 13.1 20.2 18.1 20.1 26.3 14.3 8.9 15.6 14.7 21.9 18.4 6.1 11.4 10.5 10.8 11.0 11.3 11.3 16.1 19.2 10.6 28.3 13.7 15.6 19.9 11.0 12.3 20.0 10.4 22.8 10.1 14.8 24.4 23.9 9.2 17.7 20.0 32.4 21.3 18.9 15.5 17.0 15.3 12.9 17.5 13.0 25.4 20.1 7.5 12.7 15.1 22.0 16.4 12.9 11.0 10.6 11.8 26.7 23.5 17.7 21.4 18.4 13.6 13.2 10.7 7.8 28.7 11.0 12.9 11.7 15.0 8.2 17.0 14.2 38.7 25.7 24.0 17.3 22.6 17.2 34.9 21.6 23.2 15.1 37.2 26.1 18.5 26.9 14.3 22.9 24.6 24.3 10.5 25.7 25.1 28.8 36.1 24.4 27.5 25.9 24.9 24.9 23.2 26.0 26.3 16.7 9.6 17.4 12.1 35.6 11.3 10.2 16.6 12.0 15.3 13.8 12.1 23.9 5.7 17.2 16.5 14.6 6.8 42.3 14.0 23.5 12.8 1.1 27.7 14.3 14.2 16.8 9.9 15.5 14.9 10.2 11.5 4.6 14.1 32.3 9.7 11.0 13.8 19.1 8.4 17.9 16.9 22.4 33.5 19.6 1.6 13.7 25.6 12.4 14.0 30.5 9.6 37.0 10.1 13.7 13.1 8.2 16.6 18.8 7.0 17.3 17.7 23.7 19.5 19.7 13.8 16.2 6.4 8.3 7.8 10.5 7.3 32.2 9.3 13.4 8.0