[{"Gene":"BRAF","Gene synonym":["BRAF1"],"Ensembl":"ENSG00000157764","Gene description":"B-Raf proto-oncogene, serine\/threonine kinase","Uniprot":["P15056"],"Chromosome":"7","Position":"140719327-140924929","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Deafness","Disease variant","Ectodermal dysplasia","FDA approved drug targets","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"252.3","Inhibitory neurons":"242.4","Oligodendrocyte precursor cells":"206.1","Oligodendrocytes":"202.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001328","CAB004552","HPA071048"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004552":"AB_626760","HPA001328":"AB_1078296","HPA071048":"AB_2686336"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"5.8","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"7.7","Tissue RNA - bone marrow [nTPM]":"15.9","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"8.7","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"5.4","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"9.9","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"9.8","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"17.0","Tissue RNA - salivary gland [nTPM]":"7.2","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"13.7","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"6.4","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"6.3","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"9.4","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"12.3","Cell RNA - BJ [nTPM]":"6.8","Cell RNA - BJ hTERT+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.6","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"8.4","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"5.5","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"9.8","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"7.1","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"11.7","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"7.9","Cell RNA - hTCEpi [nTPM]":"6.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"8.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.6","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"11.3","Cell RNA - Karpas-707 [nTPM]":"19.1","Cell RNA - LHCN-M2 [nTPM]":"9.8","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"10.1","Cell RNA - RH-30 [nTPM]":"6.5","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"5.3","Cell RNA - RT4 [nTPM]":"11.9","Cell RNA - SCLC-21H [nTPM]":"8.9","Cell RNA - SH-SY5Y [nTPM]":"7.3","Cell RNA - SiHa [nTPM]":"7.9","Cell RNA - SK-BR-3 [nTPM]":"4.9","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"7.5","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"9.7","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"12.9","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"21.6","Cell RNA - U-266\/84 [nTPM]":"12.9","Cell RNA - U-698 [nTPM]":"16.7","Cell RNA - U-87 MG [nTPM]":"9.7","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"6.6","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"4.1","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"7.7","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"8.7","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"43.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.7","Single Cell Type RNA - Astrocytes [nTPM]":"151.1","Single Cell Type RNA - B-cells [nTPM]":"58.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - dendritic cells [nTPM]":"73.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.3","Single Cell Type RNA - Early spermatids [nTPM]":"68.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.4","Single Cell Type RNA - Endothelial cells [nTPM]":"23.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"252.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.2","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"45.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"9.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"242.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.6","Single Cell Type RNA - Langerhans cells [nTPM]":"37.1","Single Cell Type RNA - Late spermatids [nTPM]":"36.5","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"30.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"126.5","Single Cell Type RNA - monocytes [nTPM]":"14.6","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"206.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"202.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.4","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"48.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.7","Single Cell Type RNA - Spermatocytes [nTPM]":"43.8","Single Cell Type RNA - Spermatogonia [nTPM]":"26.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - T-cells [nTPM]":"41.4","Single Cell Type RNA - Theca cells [nTPM]":"30.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.7","Single Cell Type RNA - Urothelial cells [nTPM]":"33.4"},{"Gene":"CASR","Gene synonym":["FHH","GPRC2A","HHC","HHC1","NSHPT"],"Ensembl":"ENSG00000036828","Gene description":"Calcium sensing receptor","Uniprot":["P41180"],"Chromosome":"3","Position":"122183668-122291629","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"parathyroid gland":"654.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"25.6","Alveolar cells type 2":"20.2","Cholangiocytes":"27.1","Distal tubular cells":"13.7","Enteroendocrine cells":"11.5","Granulosa cells":"20.7","Respiratory ciliated cells":"15.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"pancreatic cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039686","HPA050335"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039686":"AB_10673536","HPA050335":"AB_2681092"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"22.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"654.4","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CCDC6","Gene synonym":["D10S170","H4","PTC","TPC","TST1"],"Ensembl":"ENSG00000108091","Gene description":"Coiled-coil domain containing 6","Uniprot":["Q16204"],"Chromosome":"10","Position":"59788747-59906556","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019049","HPA019051"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019049":"AB_1846163","HPA019051":"AB_1846164"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"21.1","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"23.4","Tissue RNA - bone marrow [nTPM]":"16.8","Tissue RNA - breast [nTPM]":"22.4","Tissue RNA - cerebellum [nTPM]":"10.2","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"23.4","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"23.5","Tissue RNA - duodenum [nTPM]":"22.8","Tissue RNA - endometrium 1 [nTPM]":"24.9","Tissue RNA - epididymis [nTPM]":"16.7","Tissue RNA - esophagus [nTPM]":"34.1","Tissue RNA - fallopian tube [nTPM]":"25.3","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"24.9","Tissue RNA - hypothalamus [nTPM]":"21.4","Tissue RNA - kidney [nTPM]":"21.2","Tissue RNA - liver [nTPM]":"12.1","Tissue RNA - lung [nTPM]":"17.3","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"25.2","Tissue RNA - parathyroid gland [nTPM]":"17.9","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"19.4","Tissue RNA - rectum [nTPM]":"19.8","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"29.0","Tissue RNA - seminal vesicle [nTPM]":"14.3","Tissue RNA - skeletal muscle [nTPM]":"17.3","Tissue RNA - skin 1 [nTPM]":"28.6","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"30.8","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"18.6","Tissue RNA - testis [nTPM]":"11.4","Tissue RNA - thalamus [nTPM]":"20.8","Tissue RNA - thymus [nTPM]":"12.1","Tissue RNA - thyroid gland [nTPM]":"18.3","Tissue RNA - tongue [nTPM]":"12.2","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"17.3","Tissue RNA - vagina [nTPM]":"23.1","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"42.9","Cell RNA - A549 [nTPM]":"38.0","Cell RNA - AF22 [nTPM]":"18.7","Cell RNA - AN3-CA [nTPM]":"41.9","Cell RNA - ASC diff [nTPM]":"27.8","Cell RNA - ASC TERT1 [nTPM]":"41.6","Cell RNA - BEWO [nTPM]":"37.9","Cell RNA - BJ [nTPM]":"20.6","Cell RNA - BJ hTERT+ [nTPM]":"27.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.7","Cell RNA - CACO-2 [nTPM]":"74.4","Cell RNA - CAPAN-2 [nTPM]":"81.8","Cell RNA - Daudi [nTPM]":"36.5","Cell RNA - EFO-21 [nTPM]":"30.2","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"11.7","Cell RNA - HaCaT [nTPM]":"61.7","Cell RNA - HAP1 [nTPM]":"37.7","Cell RNA - HBEC3-KT [nTPM]":"37.5","Cell RNA - HBF TERT88 [nTPM]":"30.0","Cell RNA - HDLM-2 [nTPM]":"55.1","Cell RNA - HEK 293 [nTPM]":"18.7","Cell RNA - HEL [nTPM]":"29.8","Cell RNA - HeLa [nTPM]":"29.1","Cell RNA - Hep G2 [nTPM]":"45.5","Cell RNA - HHSteC [nTPM]":"33.5","Cell RNA - HL-60 [nTPM]":"34.5","Cell RNA - HMC-1 [nTPM]":"26.9","Cell RNA - HSkMC [nTPM]":"30.3","Cell RNA - hTCEpi [nTPM]":"48.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.7","Cell RNA - hTERT-HME1 [nTPM]":"81.8","Cell RNA - hTERT-RPE1 [nTPM]":"28.3","Cell RNA - HUVEC TERT2 [nTPM]":"30.2","Cell RNA - JURKAT [nTPM]":"20.4","Cell RNA - K-562 [nTPM]":"22.6","Cell RNA - Karpas-707 [nTPM]":"22.7","Cell RNA - LHCN-M2 [nTPM]":"26.6","Cell RNA - MCF7 [nTPM]":"57.6","Cell RNA - MOLT-4 [nTPM]":"14.5","Cell RNA - NB-4 [nTPM]":"19.8","Cell RNA - NTERA-2 [nTPM]":"29.9","Cell RNA - OE19 [nTPM]":"40.1","Cell RNA - PC-3 [nTPM]":"25.6","Cell RNA - REH [nTPM]":"19.2","Cell RNA - RH-30 [nTPM]":"30.5","Cell RNA - RPMI-8226 [nTPM]":"23.0","Cell RNA - RPTEC TERT1 [nTPM]":"33.9","Cell RNA - RT4 [nTPM]":"36.2","Cell RNA - SCLC-21H [nTPM]":"19.0","Cell RNA - SH-SY5Y [nTPM]":"16.6","Cell RNA - SiHa [nTPM]":"26.1","Cell RNA - SK-BR-3 [nTPM]":"107.8","Cell RNA - SK-MEL-30 [nTPM]":"23.1","Cell RNA - SuSa [nTPM]":"24.1","Cell RNA - T-47d [nTPM]":"68.7","Cell RNA - THP-1 [nTPM]":"18.4","Cell RNA - TIME [nTPM]":"31.1","Cell RNA - U-138 MG [nTPM]":"18.8","Cell RNA - U-2 OS [nTPM]":"33.9","Cell RNA - U-2197 [nTPM]":"29.3","Cell RNA - U-251 MG [nTPM]":"34.9","Cell RNA - U-266\/70 [nTPM]":"12.0","Cell RNA - U-266\/84 [nTPM]":"14.9","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"29.6","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"5.0","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"21.1","Brain RNA - basal ganglia [nTPM]":"23.4","Brain RNA - cerebellum [nTPM]":"10.2","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"24.9","Brain RNA - hypothalamus [nTPM]":"21.4","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"20.8","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.9","Single Cell Type RNA - Astrocytes [nTPM]":"45.1","Single Cell Type RNA - B-cells [nTPM]":"41.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"95.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"70.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"51.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"46.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.8","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"50.2","Single Cell Type RNA - Early spermatids [nTPM]":"27.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"105.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.6","Single Cell Type RNA - Endothelial cells [nTPM]":"22.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.0","Single Cell Type RNA - Erythroid cells [nTPM]":"25.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"83.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"65.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.8","Single Cell Type RNA - Fibroblasts [nTPM]":"27.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"134.5","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"45.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.9","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"40.7","Single Cell Type RNA - Langerhans cells [nTPM]":"35.3","Single Cell Type RNA - Late spermatids [nTPM]":"80.6","Single Cell Type RNA - Leydig cells [nTPM]":"24.5","Single Cell Type RNA - Macrophages [nTPM]":"36.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"23.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.5","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.2","Single Cell Type RNA - Paneth cells [nTPM]":"25.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"26.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"52.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"22.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"92.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"32.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.3","Single Cell Type RNA - Urothelial cells [nTPM]":"46.1"},{"Gene":"CDC73","Gene synonym":["C1orf28","FIHP","HRPT1","HRPT2","parafibromin"],"Ensembl":"ENSG00000134371","Gene description":"Cell division cycle 73","Uniprot":["Q6P1J9"],"Chromosome":"1","Position":"193121983-193254815","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002326","CAB016359","HPA069324"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016359":"AB_628102","HPA002326":null,"HPA069324":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"10.7","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"5.6","Tissue RNA - endometrium 1 [nTPM]":"10.3","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"9.6","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"7.2","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"9.0","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"12.2","Tissue RNA - skin 1 [nTPM]":"7.0","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"10.3","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"13.1","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"16.6","Cell RNA - AN3-CA [nTPM]":"11.5","Cell RNA - ASC diff [nTPM]":"18.3","Cell RNA - ASC TERT1 [nTPM]":"18.9","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.4","Cell RNA - CACO-2 [nTPM]":"6.5","Cell RNA - CAPAN-2 [nTPM]":"12.3","Cell RNA - Daudi [nTPM]":"10.5","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"20.4","Cell RNA - GAMG [nTPM]":"8.8","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"14.9","Cell RNA - HBF TERT88 [nTPM]":"24.7","Cell RNA - HDLM-2 [nTPM]":"6.1","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"7.2","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"16.0","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"13.7","Cell RNA - hTCEpi [nTPM]":"16.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.9","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"20.6","Cell RNA - HUVEC TERT2 [nTPM]":"17.8","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"8.1","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"28.8","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"21.9","Cell RNA - PC-3 [nTPM]":"2.5","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"15.0","Cell RNA - RPTEC TERT1 [nTPM]":"26.6","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"12.3","Cell RNA - SiHa [nTPM]":"8.6","Cell RNA - SK-BR-3 [nTPM]":"26.8","Cell RNA - SK-MEL-30 [nTPM]":"22.3","Cell RNA - SuSa [nTPM]":"21.0","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"12.6","Cell RNA - U-266\/70 [nTPM]":"12.2","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"7.6","Cell RNA - U-87 MG [nTPM]":"11.9","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"30.1","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"7.2","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"44.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.4","Single Cell Type RNA - Astrocytes [nTPM]":"54.5","Single Cell Type RNA - B-cells [nTPM]":"44.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Bipolar cells [nTPM]":"30.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"27.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.0","Single Cell Type RNA - dendritic cells [nTPM]":"48.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"19.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.6","Single Cell Type RNA - Endothelial cells [nTPM]":"38.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.0","Single Cell Type RNA - Fibroblasts [nTPM]":"39.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.8","Single Cell Type RNA - granulocytes [nTPM]":"41.1","Single Cell Type RNA - Granulosa cells [nTPM]":"17.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"27.4","Single Cell Type RNA - Langerhans cells [nTPM]":"49.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"38.3","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"46.0","Single Cell Type RNA - Muller glia cells [nTPM]":"35.2","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"112.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.5","Single Cell Type RNA - Paneth cells [nTPM]":"16.9","Single Cell Type RNA - Peritubular cells [nTPM]":"36.1","Single Cell Type RNA - Plasma cells [nTPM]":"50.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.3","Single Cell Type RNA - Spermatocytes [nTPM]":"55.6","Single Cell Type RNA - Spermatogonia [nTPM]":"33.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"44.4","Single Cell Type RNA - Theca cells [nTPM]":"30.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"27.9"},{"Gene":"CDH1","Gene synonym":["CD324","UVO","uvomorulin"],"Ensembl":"ENSG00000039068","Gene description":"Cadherin 1","Uniprot":["P12830"],"Chromosome":"16","Position":"68737292-68835537","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"197.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"451.6","Glandular and luminal cells":"321.0","Pancreatic endocrine cells":"264.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"myeloid DC":"1.7","plasmacytoid DC":"4.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"4.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"683.3","CACO-2":"241.9","CAPAN-2":"328.1","HaCaT":"318.7","hTCEpi":"217.2","MCF7":"199.6","OE19":"207.2","RT4":"237.7","T-47d":"209.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000087","HPA004812","CAB028364","CAB072855","CAB072856","CAB072857"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000087":"AB_2533003","CAB028364":"AB_2076812","CAB072855":"AB_2665698","CAB072856":"AB_2665699","CAB072857":"AB_2665700","HPA004812":"AB_1078369"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"64.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"30.0","Tissue RNA - choroid plexus [nTPM]":"19.3","Tissue RNA - colon [nTPM]":"127.5","Tissue RNA - duodenum [nTPM]":"133.9","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"39.5","Tissue RNA - esophagus [nTPM]":"76.9","Tissue RNA - fallopian tube [nTPM]":"51.5","Tissue RNA - gallbladder [nTPM]":"45.7","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"39.8","Tissue RNA - liver [nTPM]":"97.2","Tissue RNA - lung [nTPM]":"36.8","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"84.0","Tissue RNA - parathyroid gland [nTPM]":"197.8","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"60.9","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"91.7","Tissue RNA - rectum [nTPM]":"131.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"71.9","Tissue RNA - seminal vesicle [nTPM]":"41.7","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"107.7","Tissue RNA - small intestine [nTPM]":"127.9","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"104.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"20.1","Tissue RNA - thyroid gland [nTPM]":"162.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"29.0","Tissue RNA - urinary bladder [nTPM]":"58.2","Tissue RNA - vagina [nTPM]":"38.1","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"147.0","Cell RNA - A549 [nTPM]":"14.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"683.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"241.9","Cell RNA - CAPAN-2 [nTPM]":"328.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"318.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"156.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"28.6","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"48.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"217.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"199.6","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"207.2","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"53.9","Cell RNA - RT4 [nTPM]":"237.7","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"58.9","Cell RNA - SuSa [nTPM]":"91.8","Cell RNA - T-47d [nTPM]":"209.2","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"4.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"131.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"69.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"94.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"130.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"73.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"137.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"83.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"128.7","Single Cell Type RNA - Club cells [nTPM]":"95.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"163.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"117.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"451.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"129.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"159.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"86.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"113.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.6","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"132.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"321.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"63.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"208.3","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"13.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"264.6","Single Cell Type RNA - Paneth cells [nTPM]":"204.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"195.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"159.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"118.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"100.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"131.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.5","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.8","Single Cell Type RNA - Urothelial cells [nTPM]":"251.5"},{"Gene":"CDKN1B","Gene synonym":["KIP1","P27KIP1"],"Ensembl":"ENSG00000111276","Gene description":"Cyclin dependent kinase inhibitor 1B","Uniprot":["P46527"],"Chromosome":"12","Position":"12715058-12722369","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Protein kinase inhibitor"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"182.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003691","CAB021888","HPA059086"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB003691":"AB_425362","CAB021888":null,"HPA059086":"AB_2683900"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.15e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Tissue RNA - adipose tissue [nTPM]":"53.4","Tissue RNA - adrenal gland [nTPM]":"44.7","Tissue RNA - amygdala [nTPM]":"53.6","Tissue RNA - appendix [nTPM]":"40.1","Tissue RNA - basal ganglia [nTPM]":"70.6","Tissue RNA - bone marrow [nTPM]":"68.1","Tissue RNA - breast [nTPM]":"50.2","Tissue RNA - cerebellum [nTPM]":"73.4","Tissue RNA - cerebral cortex [nTPM]":"81.3","Tissue RNA - cervix [nTPM]":"55.3","Tissue RNA - choroid plexus [nTPM]":"43.1","Tissue RNA - colon [nTPM]":"43.9","Tissue RNA - duodenum [nTPM]":"44.5","Tissue RNA - endometrium 1 [nTPM]":"41.0","Tissue RNA - epididymis [nTPM]":"24.5","Tissue RNA - esophagus [nTPM]":"29.1","Tissue RNA - fallopian tube [nTPM]":"47.3","Tissue RNA - gallbladder [nTPM]":"24.6","Tissue RNA - heart muscle [nTPM]":"32.9","Tissue RNA - hippocampal formation [nTPM]":"47.9","Tissue RNA - hypothalamus [nTPM]":"58.9","Tissue RNA - kidney [nTPM]":"30.2","Tissue RNA - liver [nTPM]":"35.2","Tissue RNA - lung [nTPM]":"38.9","Tissue RNA - lymph node [nTPM]":"55.3","Tissue RNA - medulla oblongata [nTPM]":"58.6","Tissue RNA - midbrain [nTPM]":"58.3","Tissue RNA - ovary [nTPM]":"66.1","Tissue RNA - pancreas [nTPM]":"23.9","Tissue RNA - parathyroid gland [nTPM]":"34.4","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"41.0","Tissue RNA - pons [nTPM]":"61.2","Tissue RNA - prostate [nTPM]":"35.9","Tissue RNA - rectum [nTPM]":"32.5","Tissue RNA - retina [nTPM]":"55.3","Tissue RNA - salivary gland [nTPM]":"36.3","Tissue RNA - seminal vesicle [nTPM]":"33.4","Tissue RNA - skeletal muscle [nTPM]":"81.4","Tissue RNA - skin 1 [nTPM]":"45.4","Tissue RNA - small intestine [nTPM]":"40.7","Tissue RNA - smooth muscle [nTPM]":"24.8","Tissue RNA - spinal cord [nTPM]":"55.1","Tissue RNA - spleen [nTPM]":"55.1","Tissue RNA - stomach 1 [nTPM]":"30.0","Tissue RNA - testis [nTPM]":"25.8","Tissue RNA - thalamus [nTPM]":"58.3","Tissue RNA - thymus [nTPM]":"71.8","Tissue RNA - thyroid gland [nTPM]":"33.7","Tissue RNA - tongue [nTPM]":"63.4","Tissue RNA - tonsil [nTPM]":"39.9","Tissue RNA - urinary bladder [nTPM]":"32.0","Tissue RNA - vagina [nTPM]":"44.5","Tissue RNA - white matter [nTPM]":"91.2","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"16.6","Cell RNA - AF22 [nTPM]":"94.5","Cell RNA - AN3-CA [nTPM]":"16.6","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"18.0","Cell RNA - BEWO [nTPM]":"46.1","Cell RNA - BJ [nTPM]":"31.5","Cell RNA - BJ hTERT+ [nTPM]":"53.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.4","Cell RNA - CACO-2 [nTPM]":"47.7","Cell RNA - CAPAN-2 [nTPM]":"40.4","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"12.5","Cell RNA - fHDF\/TERT166 [nTPM]":"19.6","Cell RNA - GAMG [nTPM]":"16.6","Cell RNA - HaCaT [nTPM]":"34.2","Cell RNA - HAP1 [nTPM]":"44.9","Cell RNA - HBEC3-KT [nTPM]":"16.7","Cell RNA - HBF TERT88 [nTPM]":"41.1","Cell RNA - HDLM-2 [nTPM]":"62.4","Cell RNA - HEK 293 [nTPM]":"31.5","Cell RNA - HEL [nTPM]":"28.8","Cell RNA - HeLa [nTPM]":"46.5","Cell RNA - Hep G2 [nTPM]":"53.2","Cell RNA - HHSteC [nTPM]":"42.5","Cell RNA - HL-60 [nTPM]":"24.5","Cell RNA - HMC-1 [nTPM]":"18.6","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"35.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"44.0","Cell RNA - hTERT-RPE1 [nTPM]":"107.8","Cell RNA - HUVEC TERT2 [nTPM]":"27.8","Cell RNA - JURKAT [nTPM]":"54.5","Cell RNA - K-562 [nTPM]":"31.5","Cell RNA - Karpas-707 [nTPM]":"101.6","Cell RNA - LHCN-M2 [nTPM]":"16.6","Cell RNA - MCF7 [nTPM]":"45.9","Cell RNA - MOLT-4 [nTPM]":"32.7","Cell RNA - NB-4 [nTPM]":"35.3","Cell RNA - NTERA-2 [nTPM]":"38.0","Cell RNA - OE19 [nTPM]":"32.1","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"25.2","Cell RNA - RH-30 [nTPM]":"30.9","Cell RNA - RPMI-8226 [nTPM]":"63.1","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"38.6","Cell RNA - SCLC-21H [nTPM]":"35.6","Cell RNA - SH-SY5Y [nTPM]":"58.4","Cell RNA - SiHa [nTPM]":"48.9","Cell RNA - SK-BR-3 [nTPM]":"34.8","Cell RNA - SK-MEL-30 [nTPM]":"65.8","Cell RNA - SuSa [nTPM]":"33.7","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"54.6","Cell RNA - TIME [nTPM]":"19.1","Cell RNA - U-138 MG [nTPM]":"22.6","Cell RNA - U-2 OS [nTPM]":"34.9","Cell RNA - U-2197 [nTPM]":"20.7","Cell RNA - U-251 MG [nTPM]":"33.3","Cell RNA - U-266\/70 [nTPM]":"86.1","Cell RNA - U-266\/84 [nTPM]":"59.4","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"28.2","Cell RNA - U-937 [nTPM]":"36.6","Cell RNA - WM-115 [nTPM]":"22.5","Blood RNA - basophil [nTPM]":"6.2","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"8.6","Blood RNA - gdT-cell [nTPM]":"5.9","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"6.1","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"7.2","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"5.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.1","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"7.3","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"12.3","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"53.6","Brain RNA - basal ganglia [nTPM]":"70.6","Brain RNA - cerebellum [nTPM]":"73.4","Brain RNA - cerebral cortex [nTPM]":"81.3","Brain RNA - hippocampal formation [nTPM]":"47.9","Brain RNA - hypothalamus [nTPM]":"58.9","Brain RNA - medulla oblongata [nTPM]":"58.6","Brain RNA - midbrain [nTPM]":"58.3","Brain RNA - pons [nTPM]":"61.2","Brain RNA - spinal cord [nTPM]":"55.1","Brain RNA - thalamus [nTPM]":"58.3","Brain RNA - white matter [nTPM]":"91.2","Single Cell Type RNA - Adipocytes [nTPM]":"64.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"126.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"115.5","Single Cell Type RNA - Bipolar cells [nTPM]":"45.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"27.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.9","Single Cell Type RNA - dendritic cells [nTPM]":"92.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.8","Single Cell Type RNA - Early spermatids [nTPM]":"70.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.8","Single Cell Type RNA - Endothelial cells [nTPM]":"51.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.7","Single Cell Type RNA - Erythroid cells [nTPM]":"70.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.6","Single Cell Type RNA - Fibroblasts [nTPM]":"39.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.3","Single Cell Type RNA - granulocytes [nTPM]":"31.0","Single Cell Type RNA - Granulosa cells [nTPM]":"21.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.2","Single Cell Type RNA - Hepatocytes [nTPM]":"30.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.4","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"55.3","Single Cell Type RNA - Langerhans cells [nTPM]":"66.0","Single Cell Type RNA - Late spermatids [nTPM]":"67.7","Single Cell Type RNA - Leydig cells [nTPM]":"55.9","Single Cell Type RNA - Macrophages [nTPM]":"65.1","Single Cell Type RNA - Melanocytes [nTPM]":"74.7","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"31.6","Single Cell Type RNA - Muller glia cells [nTPM]":"182.9","Single Cell Type RNA - NK-cells [nTPM]":"60.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.3","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"121.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.4","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.7","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"102.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"52.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.0","Single Cell Type RNA - T-cells [nTPM]":"166.1","Single Cell Type RNA - Theca cells [nTPM]":"20.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.9","Single Cell Type RNA - Urothelial cells [nTPM]":"22.7"},{"Gene":"CDKN1C","Gene synonym":["BWCR","BWS","KIP2","P57"],"Ensembl":"ENSG00000129757","Gene description":"Cyclin dependent kinase inhibitor 1C","Uniprot":["P49918"],"Chromosome":"11","Position":"2883213-2885775","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Protein kinase inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"206.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"575.3","Extravillous trophoblasts":"1531.7","Syncytiotrophoblasts":"2241.2","Theca cells":"781.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"intermediate monocyte":"155.1","non-classical monocyte":"376.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"monocytes":"376.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"12.0","HeLa":"12.8","RPMI-8226":"18.7","SH-SY5Y":"33.0","SiHa":"25.2","SK-MEL-30":"15.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002924"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA002924":"AB_1079548"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Tissue RNA - adipose tissue [nTPM]":"127.4","Tissue RNA - adrenal gland [nTPM]":"182.9","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"38.0","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"92.5","Tissue RNA - cerebellum [nTPM]":"43.3","Tissue RNA - cerebral cortex [nTPM]":"18.7","Tissue RNA - cervix [nTPM]":"73.7","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"48.1","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"70.6","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"29.9","Tissue RNA - fallopian tube [nTPM]":"70.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"82.6","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"18.8","Tissue RNA - kidney [nTPM]":"149.5","Tissue RNA - liver [nTPM]":"8.3","Tissue RNA - lung [nTPM]":"34.5","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"55.1","Tissue RNA - midbrain [nTPM]":"33.5","Tissue RNA - ovary [nTPM]":"206.4","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"27.8","Tissue RNA - placenta [nTPM]":"28.1","Tissue RNA - pons [nTPM]":"45.0","Tissue RNA - prostate [nTPM]":"33.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"21.7","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"60.3","Tissue RNA - skin 1 [nTPM]":"26.6","Tissue RNA - small intestine [nTPM]":"25.0","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"31.8","Tissue RNA - spleen [nTPM]":"20.6","Tissue RNA - stomach 1 [nTPM]":"54.1","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"34.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"75.0","Tissue RNA - vagina [nTPM]":"49.4","Tissue RNA - white matter [nTPM]":"95.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"5.6","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"12.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"4.0","Cell RNA - REH [nTPM]":"2.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"18.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.5","Cell RNA - SH-SY5Y [nTPM]":"33.0","Cell RNA - SiHa [nTPM]":"25.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"15.2","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.8","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"155.1","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"26.9","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"376.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"38.0","Brain RNA - cerebellum [nTPM]":"43.3","Brain RNA - cerebral cortex [nTPM]":"18.7","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"18.8","Brain RNA - medulla oblongata [nTPM]":"55.1","Brain RNA - midbrain [nTPM]":"33.5","Brain RNA - pons [nTPM]":"45.0","Brain RNA - spinal cord [nTPM]":"31.8","Brain RNA - thalamus [nTPM]":"34.3","Brain RNA - white matter [nTPM]":"95.3","Single Cell Type RNA - Adipocytes [nTPM]":"357.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"11.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"81.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"11.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"150.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"575.3","Single Cell Type RNA - dendritic cells [nTPM]":"46.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"176.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.5","Single Cell Type RNA - Endothelial cells [nTPM]":"100.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"106.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1531.7","Single Cell Type RNA - Fibroblasts [nTPM]":"141.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"56.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"31.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"91.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.5","Single Cell Type RNA - Langerhans cells [nTPM]":"23.2","Single Cell Type RNA - Late spermatids [nTPM]":"276.4","Single Cell Type RNA - Leydig cells [nTPM]":"74.3","Single Cell Type RNA - Macrophages [nTPM]":"54.9","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"14.1","Single Cell Type RNA - Muller glia cells [nTPM]":"68.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.3","Single Cell Type RNA - Paneth cells [nTPM]":"4.2","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"64.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"78.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"238.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"71.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2241.2","Single Cell Type RNA - T-cells [nTPM]":"25.1","Single Cell Type RNA - Theca cells [nTPM]":"781.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.2","Single Cell Type RNA - Urothelial cells [nTPM]":"71.8"},{"Gene":"CTNNB1","Gene synonym":["armadillo","beta-catenin","CTNNB"],"Ensembl":"ENSG00000168036","Gene description":"Catenin beta 1","Uniprot":["P35222"],"Chromosome":"3","Position":"41194741-41260096","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"539.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000108","CAB001950","HPA029159","HPA029160"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000108":null,"CAB001950":null,"HPA029159":"AB_10599619","HPA029160":"AB_10600996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"130.8","Tissue RNA - adrenal gland [nTPM]":"112.2","Tissue RNA - amygdala [nTPM]":"106.7","Tissue RNA - appendix [nTPM]":"98.7","Tissue RNA - basal ganglia [nTPM]":"85.3","Tissue RNA - bone marrow [nTPM]":"162.4","Tissue RNA - breast [nTPM]":"194.3","Tissue RNA - cerebellum [nTPM]":"147.8","Tissue RNA - cerebral cortex [nTPM]":"87.5","Tissue RNA - cervix [nTPM]":"179.4","Tissue RNA - choroid plexus [nTPM]":"94.7","Tissue RNA - colon [nTPM]":"141.2","Tissue RNA - duodenum [nTPM]":"136.9","Tissue RNA - endometrium 1 [nTPM]":"149.4","Tissue RNA - epididymis [nTPM]":"84.4","Tissue RNA - esophagus [nTPM]":"113.7","Tissue RNA - fallopian tube [nTPM]":"131.0","Tissue RNA - gallbladder [nTPM]":"121.8","Tissue RNA - heart muscle [nTPM]":"109.9","Tissue RNA - hippocampal formation [nTPM]":"88.1","Tissue RNA - hypothalamus [nTPM]":"105.3","Tissue RNA - kidney [nTPM]":"106.5","Tissue RNA - liver [nTPM]":"147.9","Tissue RNA - lung [nTPM]":"132.9","Tissue RNA - lymph node [nTPM]":"81.9","Tissue RNA - medulla oblongata [nTPM]":"101.3","Tissue RNA - midbrain [nTPM]":"112.9","Tissue RNA - ovary [nTPM]":"173.9","Tissue RNA - pancreas [nTPM]":"93.3","Tissue RNA - parathyroid gland [nTPM]":"137.2","Tissue RNA - pituitary gland [nTPM]":"84.7","Tissue RNA - placenta [nTPM]":"200.0","Tissue RNA - pons [nTPM]":"94.0","Tissue RNA - prostate [nTPM]":"132.3","Tissue RNA - rectum [nTPM]":"134.5","Tissue RNA - retina [nTPM]":"88.8","Tissue RNA - salivary gland [nTPM]":"110.9","Tissue RNA - seminal vesicle [nTPM]":"126.3","Tissue RNA - skeletal muscle [nTPM]":"87.3","Tissue RNA - skin 1 [nTPM]":"99.0","Tissue RNA - small intestine [nTPM]":"142.9","Tissue RNA - smooth muscle [nTPM]":"178.4","Tissue RNA - spinal cord [nTPM]":"104.9","Tissue RNA - spleen [nTPM]":"92.5","Tissue RNA - stomach 1 [nTPM]":"81.8","Tissue RNA - testis [nTPM]":"59.5","Tissue RNA - thalamus [nTPM]":"129.4","Tissue RNA - thymus [nTPM]":"95.6","Tissue RNA - thyroid gland [nTPM]":"140.6","Tissue RNA - tongue [nTPM]":"89.9","Tissue RNA - tonsil [nTPM]":"99.5","Tissue RNA - urinary bladder [nTPM]":"158.3","Tissue RNA - vagina [nTPM]":"109.3","Tissue RNA - white matter [nTPM]":"108.4","Cell RNA - A-431 [nTPM]":"161.6","Cell RNA - A549 [nTPM]":"210.0","Cell RNA - AF22 [nTPM]":"423.6","Cell RNA - AN3-CA [nTPM]":"242.8","Cell RNA - ASC diff [nTPM]":"226.9","Cell RNA - ASC TERT1 [nTPM]":"184.7","Cell RNA - BEWO [nTPM]":"333.8","Cell RNA - BJ [nTPM]":"179.6","Cell RNA - BJ hTERT+ [nTPM]":"249.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"288.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"284.3","Cell RNA - CACO-2 [nTPM]":"146.3","Cell RNA - CAPAN-2 [nTPM]":"224.0","Cell RNA - Daudi [nTPM]":"131.7","Cell RNA - EFO-21 [nTPM]":"157.8","Cell RNA - fHDF\/TERT166 [nTPM]":"314.1","Cell RNA - GAMG [nTPM]":"129.0","Cell RNA - HaCaT [nTPM]":"119.6","Cell RNA - HAP1 [nTPM]":"315.8","Cell RNA - HBEC3-KT [nTPM]":"510.0","Cell RNA - HBF TERT88 [nTPM]":"306.2","Cell RNA - HDLM-2 [nTPM]":"123.3","Cell RNA - HEK 293 [nTPM]":"215.7","Cell RNA - HEL [nTPM]":"215.5","Cell RNA - HeLa [nTPM]":"261.0","Cell RNA - Hep G2 [nTPM]":"523.7","Cell RNA - HHSteC [nTPM]":"169.5","Cell RNA - HL-60 [nTPM]":"121.8","Cell RNA - HMC-1 [nTPM]":"99.1","Cell RNA - HSkMC [nTPM]":"271.6","Cell RNA - hTCEpi [nTPM]":"226.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"345.5","Cell RNA - hTERT-HME1 [nTPM]":"208.7","Cell RNA - hTERT-RPE1 [nTPM]":"235.7","Cell RNA - HUVEC TERT2 [nTPM]":"258.1","Cell RNA - JURKAT [nTPM]":"63.0","Cell RNA - K-562 [nTPM]":"153.7","Cell RNA - Karpas-707 [nTPM]":"80.3","Cell RNA - LHCN-M2 [nTPM]":"324.1","Cell RNA - MCF7 [nTPM]":"161.8","Cell RNA - MOLT-4 [nTPM]":"87.3","Cell RNA - NB-4 [nTPM]":"68.3","Cell RNA - NTERA-2 [nTPM]":"397.2","Cell RNA - OE19 [nTPM]":"211.0","Cell RNA - PC-3 [nTPM]":"159.3","Cell RNA - REH [nTPM]":"64.9","Cell RNA - RH-30 [nTPM]":"281.9","Cell RNA - RPMI-8226 [nTPM]":"88.3","Cell RNA - RPTEC TERT1 [nTPM]":"177.9","Cell RNA - RT4 [nTPM]":"494.8","Cell RNA - SCLC-21H [nTPM]":"102.9","Cell RNA - SH-SY5Y [nTPM]":"172.4","Cell RNA - SiHa [nTPM]":"296.2","Cell RNA - SK-BR-3 [nTPM]":"147.1","Cell RNA - SK-MEL-30 [nTPM]":"809.4","Cell RNA - SuSa [nTPM]":"509.8","Cell RNA - T-47d [nTPM]":"242.1","Cell RNA - THP-1 [nTPM]":"248.6","Cell RNA - TIME [nTPM]":"340.8","Cell RNA - U-138 MG [nTPM]":"217.1","Cell RNA - U-2 OS [nTPM]":"163.6","Cell RNA - U-2197 [nTPM]":"139.3","Cell RNA - U-251 MG [nTPM]":"264.0","Cell RNA - U-266\/70 [nTPM]":"50.7","Cell RNA - U-266\/84 [nTPM]":"82.7","Cell RNA - U-698 [nTPM]":"138.4","Cell RNA - U-87 MG [nTPM]":"221.5","Cell RNA - U-937 [nTPM]":"150.5","Cell RNA - WM-115 [nTPM]":"369.7","Blood RNA - basophil [nTPM]":"4.7","Blood RNA - classical monocyte [nTPM]":"7.3","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"9.2","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"10.9","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.6","Blood RNA - memory CD8 T-cell [nTPM]":"10.1","Blood RNA - myeloid DC [nTPM]":"11.8","Blood RNA - naive B-cell [nTPM]":"8.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.6","Blood RNA - naive CD8 T-cell [nTPM]":"9.4","Blood RNA - neutrophil [nTPM]":"6.6","Blood RNA - NK-cell [nTPM]":"9.6","Blood RNA - non-classical monocyte [nTPM]":"12.6","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"10.8","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"106.7","Brain RNA - basal ganglia [nTPM]":"85.3","Brain RNA - cerebellum [nTPM]":"147.8","Brain RNA - cerebral cortex [nTPM]":"87.5","Brain RNA - hippocampal formation [nTPM]":"88.1","Brain RNA - hypothalamus [nTPM]":"105.3","Brain RNA - medulla oblongata [nTPM]":"101.3","Brain RNA - midbrain [nTPM]":"112.9","Brain RNA - pons [nTPM]":"94.0","Brain RNA - spinal cord [nTPM]":"104.9","Brain RNA - thalamus [nTPM]":"129.4","Brain RNA - white matter [nTPM]":"108.4","Single Cell Type RNA - Adipocytes [nTPM]":"171.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"137.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"179.5","Single Cell Type RNA - Astrocytes [nTPM]":"58.1","Single Cell Type RNA - B-cells [nTPM]":"71.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"213.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"130.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"116.1","Single Cell Type RNA - Bipolar cells [nTPM]":"40.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"232.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"168.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"84.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"119.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"318.9","Single Cell Type RNA - dendritic cells [nTPM]":"99.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"251.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"132.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"90.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"125.9","Single Cell Type RNA - Endothelial cells [nTPM]":"187.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"93.8","Single Cell Type RNA - Erythroid cells [nTPM]":"43.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"78.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"115.6","Single Cell Type RNA - Fibroblasts [nTPM]":"116.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.5","Single Cell Type RNA - granulocytes [nTPM]":"116.6","Single Cell Type RNA - Granulosa cells [nTPM]":"137.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"139.2","Single Cell Type RNA - Hepatocytes [nTPM]":"172.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"115.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"145.9","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"154.6","Single Cell Type RNA - Langerhans cells [nTPM]":"228.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"59.7","Single Cell Type RNA - Macrophages [nTPM]":"161.1","Single Cell Type RNA - Melanocytes [nTPM]":"202.7","Single Cell Type RNA - Microglial cells [nTPM]":"124.6","Single Cell Type RNA - monocytes [nTPM]":"98.3","Single Cell Type RNA - Muller glia cells [nTPM]":"89.2","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"70.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"139.8","Single Cell Type RNA - Paneth cells [nTPM]":"249.5","Single Cell Type RNA - Peritubular cells [nTPM]":"86.9","Single Cell Type RNA - Plasma cells [nTPM]":"55.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"128.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"160.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"93.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"96.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"175.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"137.3","Single Cell Type RNA - Spermatocytes [nTPM]":"78.4","Single Cell Type RNA - Spermatogonia [nTPM]":"40.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"70.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"174.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"539.5","Single Cell Type RNA - T-cells [nTPM]":"77.0","Single Cell Type RNA - Theca cells [nTPM]":"245.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"189.6","Single Cell Type RNA - Urothelial cells [nTPM]":"127.9"},{"Gene":"EPAS1","Gene synonym":["bHLHe73","HIF2A","HLF","MOP2","PASD2"],"Ensembl":"ENSG00000116016","Gene description":"Endothelial PAS domain protein 1","Uniprot":["Q99814"],"Chromosome":"2","Position":"46293667-46386697","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Angiogenesis","Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Congenital erythrocytosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"412.0","placenta":"445.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"831.5","Endothelial cells":"425.8","Hepatic stellate cells":"538.7","Syncytiotrophoblasts":"349.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"basophil":"20.6","eosinophil":"8.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"granulocytes":"20.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"267.3","BJ hTERT+":"266.7","HHSteC":"326.3","RT4":"339.8","TIME":"337.8","U-138 MG":"284.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031200","HPA069697"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031200":"AB_2673785","HPA069697":"AB_2732139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"296.0","Tissue RNA - adrenal gland [nTPM]":"52.1","Tissue RNA - amygdala [nTPM]":"53.4","Tissue RNA - appendix [nTPM]":"66.1","Tissue RNA - basal ganglia [nTPM]":"48.6","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"166.7","Tissue RNA - cerebellum [nTPM]":"44.6","Tissue RNA - cerebral cortex [nTPM]":"47.7","Tissue RNA - cervix [nTPM]":"72.9","Tissue RNA - choroid plexus [nTPM]":"139.1","Tissue RNA - colon [nTPM]":"57.1","Tissue RNA - duodenum [nTPM]":"46.3","Tissue RNA - endometrium 1 [nTPM]":"87.9","Tissue RNA - epididymis [nTPM]":"26.0","Tissue RNA - esophagus [nTPM]":"72.7","Tissue RNA - fallopian tube [nTPM]":"80.1","Tissue RNA - gallbladder [nTPM]":"83.2","Tissue RNA - heart muscle [nTPM]":"122.1","Tissue RNA - hippocampal formation [nTPM]":"39.2","Tissue RNA - hypothalamus [nTPM]":"44.7","Tissue RNA - kidney [nTPM]":"89.5","Tissue RNA - liver [nTPM]":"110.1","Tissue RNA - lung [nTPM]":"412.0","Tissue RNA - lymph node [nTPM]":"47.9","Tissue RNA - medulla oblongata [nTPM]":"60.5","Tissue RNA - midbrain [nTPM]":"54.2","Tissue RNA - ovary [nTPM]":"34.5","Tissue RNA - pancreas [nTPM]":"59.6","Tissue RNA - parathyroid gland [nTPM]":"79.4","Tissue RNA - pituitary gland [nTPM]":"25.9","Tissue RNA - placenta [nTPM]":"445.6","Tissue RNA - pons [nTPM]":"60.2","Tissue RNA - prostate [nTPM]":"51.8","Tissue RNA - rectum [nTPM]":"42.6","Tissue RNA - retina [nTPM]":"53.6","Tissue RNA - salivary gland [nTPM]":"40.0","Tissue RNA - seminal vesicle [nTPM]":"66.3","Tissue RNA - skeletal muscle [nTPM]":"80.5","Tissue RNA - skin 1 [nTPM]":"42.9","Tissue RNA - small intestine [nTPM]":"50.9","Tissue RNA - smooth muscle [nTPM]":"71.7","Tissue RNA - spinal cord [nTPM]":"45.6","Tissue RNA - spleen [nTPM]":"84.6","Tissue RNA - stomach 1 [nTPM]":"42.8","Tissue RNA - testis [nTPM]":"20.0","Tissue RNA - thalamus [nTPM]":"75.4","Tissue RNA - thymus [nTPM]":"17.9","Tissue RNA - thyroid gland [nTPM]":"138.1","Tissue RNA - tongue [nTPM]":"153.6","Tissue RNA - tonsil [nTPM]":"40.3","Tissue RNA - urinary bladder [nTPM]":"94.9","Tissue RNA - vagina [nTPM]":"47.8","Tissue RNA - white matter [nTPM]":"44.6","Cell RNA - A-431 [nTPM]":"32.2","Cell RNA - A549 [nTPM]":"33.5","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"2.5","Cell RNA - ASC diff [nTPM]":"153.8","Cell RNA - ASC TERT1 [nTPM]":"98.6","Cell RNA - BEWO [nTPM]":"267.3","Cell RNA - BJ [nTPM]":"98.7","Cell RNA - BJ hTERT+ [nTPM]":"266.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.1","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"5.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"23.8","Cell RNA - fHDF\/TERT166 [nTPM]":"188.5","Cell RNA - GAMG [nTPM]":"55.2","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"79.0","Cell RNA - HBF TERT88 [nTPM]":"41.3","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"10.3","Cell RNA - Hep G2 [nTPM]":"71.8","Cell RNA - HHSteC [nTPM]":"326.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"19.8","Cell RNA - HSkMC [nTPM]":"145.0","Cell RNA - hTCEpi [nTPM]":"106.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.7","Cell RNA - hTERT-HME1 [nTPM]":"75.8","Cell RNA - hTERT-RPE1 [nTPM]":"41.0","Cell RNA - HUVEC TERT2 [nTPM]":"193.1","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"34.2","Cell RNA - MCF7 [nTPM]":"27.8","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"22.4","Cell RNA - PC-3 [nTPM]":"18.5","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"10.5","Cell RNA - RPTEC TERT1 [nTPM]":"34.5","Cell RNA - RT4 [nTPM]":"339.8","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"68.5","Cell RNA - SiHa [nTPM]":"77.4","Cell RNA - SK-BR-3 [nTPM]":"175.5","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"68.3","Cell RNA - T-47d [nTPM]":"11.7","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"337.8","Cell RNA - U-138 MG [nTPM]":"284.0","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"38.3","Cell RNA - U-251 MG [nTPM]":"8.4","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"207.4","Cell RNA - U-937 [nTPM]":"5.4","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"20.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"8.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"53.4","Brain RNA - basal ganglia [nTPM]":"48.6","Brain RNA - cerebellum [nTPM]":"44.6","Brain RNA - cerebral cortex [nTPM]":"47.7","Brain RNA - hippocampal formation [nTPM]":"39.2","Brain RNA - hypothalamus [nTPM]":"44.7","Brain RNA - medulla oblongata [nTPM]":"60.5","Brain RNA - midbrain [nTPM]":"54.2","Brain RNA - pons [nTPM]":"60.2","Brain RNA - spinal cord [nTPM]":"45.6","Brain RNA - thalamus [nTPM]":"75.4","Brain RNA - white matter [nTPM]":"44.6","Single Cell Type RNA - Adipocytes [nTPM]":"831.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"151.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"48.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"69.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"108.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"79.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"124.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"126.2","Single Cell Type RNA - dendritic cells [nTPM]":"6.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"112.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.7","Single Cell Type RNA - Endothelial cells [nTPM]":"425.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"299.9","Single Cell Type RNA - Fibroblasts [nTPM]":"76.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"67.6","Single Cell Type RNA - granulocytes [nTPM]":"41.2","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"538.7","Single Cell Type RNA - Hepatocytes [nTPM]":"78.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"55.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"60.9","Single Cell Type RNA - Langerhans cells [nTPM]":"30.3","Single Cell Type RNA - Late spermatids [nTPM]":"52.7","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"21.4","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"155.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"95.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.1","Single Cell Type RNA - Paneth cells [nTPM]":"53.7","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.3","Single Cell Type RNA - Sertoli cells [nTPM]":"282.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"250.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"65.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"349.7","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.6","Single Cell Type RNA - Urothelial cells [nTPM]":"85.7"},{"Gene":"FH","Gene synonym":[],"Ensembl":"ENSG00000091483","Gene description":"Fumarate hydratase","Uniprot":["P07954"],"Chromosome":"1","Position":"241497603-241519755","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Tricarboxylic acid cycle"],"Molecular function":["Lyase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"276.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"173.5","Early spermatids":"226.0","Syncytiotrophoblasts":"166.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017785","HPA025770","HPA025948","HPA027341"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB017785":null,"HPA025770":"AB_10599603","HPA025948":"AB_10602177","HPA027341":"AB_10601222"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.4","Tissue RNA - adrenal gland [nTPM]":"75.2","Tissue RNA - amygdala [nTPM]":"30.4","Tissue RNA - appendix [nTPM]":"31.0","Tissue RNA - basal ganglia [nTPM]":"33.3","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"37.3","Tissue RNA - cerebellum [nTPM]":"33.5","Tissue RNA - cerebral cortex [nTPM]":"42.0","Tissue RNA - cervix [nTPM]":"28.9","Tissue RNA - choroid plexus [nTPM]":"43.9","Tissue RNA - colon [nTPM]":"66.8","Tissue RNA - duodenum [nTPM]":"68.2","Tissue RNA - endometrium 1 [nTPM]":"36.9","Tissue RNA - epididymis [nTPM]":"26.1","Tissue RNA - esophagus [nTPM]":"51.1","Tissue RNA - fallopian tube [nTPM]":"27.9","Tissue RNA - gallbladder [nTPM]":"23.7","Tissue RNA - heart muscle [nTPM]":"179.0","Tissue RNA - hippocampal formation [nTPM]":"33.9","Tissue RNA - hypothalamus [nTPM]":"33.1","Tissue RNA - kidney [nTPM]":"101.8","Tissue RNA - liver [nTPM]":"276.4","Tissue RNA - lung [nTPM]":"26.4","Tissue RNA - lymph node [nTPM]":"30.0","Tissue RNA - medulla oblongata [nTPM]":"31.8","Tissue RNA - midbrain [nTPM]":"31.0","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"38.1","Tissue RNA - parathyroid gland [nTPM]":"95.0","Tissue RNA - pituitary gland [nTPM]":"31.1","Tissue RNA - placenta [nTPM]":"32.1","Tissue RNA - pons [nTPM]":"32.1","Tissue RNA - prostate [nTPM]":"33.5","Tissue RNA - rectum [nTPM]":"69.0","Tissue RNA - retina [nTPM]":"58.8","Tissue RNA - salivary gland [nTPM]":"42.0","Tissue RNA - seminal vesicle [nTPM]":"38.4","Tissue RNA - skeletal muscle [nTPM]":"213.4","Tissue RNA - skin 1 [nTPM]":"40.3","Tissue RNA - small intestine [nTPM]":"59.1","Tissue RNA - smooth muscle [nTPM]":"42.0","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"30.1","Tissue RNA - stomach 1 [nTPM]":"53.6","Tissue RNA - testis [nTPM]":"44.4","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"31.3","Tissue RNA - thyroid gland [nTPM]":"34.6","Tissue RNA - tongue [nTPM]":"229.3","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"33.7","Tissue RNA - white matter [nTPM]":"33.0","Cell RNA - A-431 [nTPM]":"129.2","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"97.9","Cell RNA - AN3-CA [nTPM]":"89.0","Cell RNA - ASC diff [nTPM]":"93.9","Cell RNA - ASC TERT1 [nTPM]":"110.0","Cell RNA - BEWO [nTPM]":"154.9","Cell RNA - BJ [nTPM]":"155.7","Cell RNA - BJ hTERT+ [nTPM]":"121.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"171.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.1","Cell RNA - CACO-2 [nTPM]":"152.2","Cell RNA - CAPAN-2 [nTPM]":"78.0","Cell RNA - Daudi [nTPM]":"81.1","Cell RNA - EFO-21 [nTPM]":"100.3","Cell RNA - fHDF\/TERT166 [nTPM]":"119.9","Cell RNA - GAMG [nTPM]":"75.0","Cell RNA - HaCaT [nTPM]":"178.4","Cell RNA - HAP1 [nTPM]":"151.7","Cell RNA - HBEC3-KT [nTPM]":"115.8","Cell RNA - HBF TERT88 [nTPM]":"148.4","Cell RNA - HDLM-2 [nTPM]":"93.5","Cell RNA - HEK 293 [nTPM]":"48.9","Cell RNA - HEL [nTPM]":"76.3","Cell RNA - HeLa [nTPM]":"102.2","Cell RNA - Hep G2 [nTPM]":"131.4","Cell RNA - HHSteC [nTPM]":"84.1","Cell RNA - HL-60 [nTPM]":"180.2","Cell RNA - HMC-1 [nTPM]":"66.7","Cell RNA - HSkMC [nTPM]":"80.2","Cell RNA - hTCEpi [nTPM]":"70.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"96.6","Cell RNA - hTERT-HME1 [nTPM]":"108.0","Cell RNA - hTERT-RPE1 [nTPM]":"60.2","Cell RNA - HUVEC TERT2 [nTPM]":"107.2","Cell RNA - JURKAT [nTPM]":"175.8","Cell RNA - K-562 [nTPM]":"236.3","Cell RNA - Karpas-707 [nTPM]":"101.7","Cell RNA - LHCN-M2 [nTPM]":"126.9","Cell RNA - MCF7 [nTPM]":"64.3","Cell RNA - MOLT-4 [nTPM]":"156.6","Cell RNA - NB-4 [nTPM]":"120.1","Cell RNA - NTERA-2 [nTPM]":"104.5","Cell RNA - OE19 [nTPM]":"186.2","Cell RNA - PC-3 [nTPM]":"223.6","Cell RNA - REH [nTPM]":"127.4","Cell RNA - RH-30 [nTPM]":"107.2","Cell RNA - RPMI-8226 [nTPM]":"365.7","Cell RNA - RPTEC TERT1 [nTPM]":"167.4","Cell RNA - RT4 [nTPM]":"107.6","Cell RNA - SCLC-21H [nTPM]":"125.4","Cell RNA - SH-SY5Y [nTPM]":"108.4","Cell RNA - SiHa [nTPM]":"131.1","Cell RNA - SK-BR-3 [nTPM]":"153.3","Cell RNA - SK-MEL-30 [nTPM]":"104.0","Cell RNA - SuSa [nTPM]":"67.2","Cell RNA - T-47d [nTPM]":"117.1","Cell RNA - THP-1 [nTPM]":"120.9","Cell RNA - TIME [nTPM]":"106.5","Cell RNA - U-138 MG [nTPM]":"76.6","Cell RNA - U-2 OS [nTPM]":"98.9","Cell RNA - U-2197 [nTPM]":"137.0","Cell RNA - U-251 MG [nTPM]":"264.0","Cell RNA - U-266\/70 [nTPM]":"90.3","Cell RNA - U-266\/84 [nTPM]":"103.7","Cell RNA - U-698 [nTPM]":"97.3","Cell RNA - U-87 MG [nTPM]":"85.7","Cell RNA - U-937 [nTPM]":"203.5","Cell RNA - WM-115 [nTPM]":"112.6","Blood RNA - basophil [nTPM]":"11.9","Blood RNA - classical monocyte [nTPM]":"22.8","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"16.1","Blood RNA - intermediate monocyte [nTPM]":"33.3","Blood RNA - MAIT T-cell [nTPM]":"21.0","Blood RNA - memory B-cell [nTPM]":"27.2","Blood RNA - memory CD4 T-cell [nTPM]":"18.8","Blood RNA - memory CD8 T-cell [nTPM]":"15.1","Blood RNA - myeloid DC [nTPM]":"46.7","Blood RNA - naive B-cell [nTPM]":"25.1","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"21.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"18.3","Blood RNA - non-classical monocyte [nTPM]":"29.1","Blood RNA - plasmacytoid DC [nTPM]":"23.1","Blood RNA - T-reg [nTPM]":"23.8","Blood RNA - total PBMC [nTPM]":"16.7","Brain RNA - amygdala [nTPM]":"30.4","Brain RNA - basal ganglia [nTPM]":"33.3","Brain RNA - cerebellum [nTPM]":"33.5","Brain RNA - cerebral cortex [nTPM]":"42.0","Brain RNA - hippocampal formation [nTPM]":"33.9","Brain RNA - hypothalamus [nTPM]":"33.1","Brain RNA - medulla oblongata [nTPM]":"31.8","Brain RNA - midbrain [nTPM]":"31.0","Brain RNA - pons [nTPM]":"32.1","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"33.0","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"25.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"173.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"40.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.6","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"78.2","Single Cell Type RNA - Ductal cells [nTPM]":"60.4","Single Cell Type RNA - Early spermatids [nTPM]":"226.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"37.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.7","Single Cell Type RNA - Fibroblasts [nTPM]":"25.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"80.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.7","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"37.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"27.9","Single Cell Type RNA - Muller glia cells [nTPM]":"35.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"35.7","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"41.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"67.9","Single Cell Type RNA - Spermatocytes [nTPM]":"84.7","Single Cell Type RNA - Spermatogonia [nTPM]":"47.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"166.1","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"48.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"74.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.8"},{"Gene":"GNAI2","Gene synonym":["GIP","GNAI2B"],"Ensembl":"ENSG00000114353","Gene description":"G protein subunit alpha i2","Uniprot":["P04899"],"Chromosome":"3","Position":"50226292-50259362","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"656.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007704"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA007704":"AB_1849230"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"210.2","Tissue RNA - adrenal gland [nTPM]":"100.3","Tissue RNA - amygdala [nTPM]":"155.2","Tissue RNA - appendix [nTPM]":"217.9","Tissue RNA - basal ganglia [nTPM]":"167.3","Tissue RNA - bone marrow [nTPM]":"367.1","Tissue RNA - breast [nTPM]":"152.8","Tissue RNA - cerebellum [nTPM]":"166.3","Tissue RNA - cerebral cortex [nTPM]":"181.6","Tissue RNA - cervix [nTPM]":"146.0","Tissue RNA - choroid plexus [nTPM]":"120.2","Tissue RNA - colon [nTPM]":"142.1","Tissue RNA - duodenum [nTPM]":"69.9","Tissue RNA - endometrium 1 [nTPM]":"141.7","Tissue RNA - epididymis [nTPM]":"66.9","Tissue RNA - esophagus [nTPM]":"124.4","Tissue RNA - fallopian tube [nTPM]":"136.9","Tissue RNA - gallbladder [nTPM]":"152.5","Tissue RNA - heart muscle [nTPM]":"157.1","Tissue RNA - hippocampal formation [nTPM]":"144.3","Tissue RNA - hypothalamus [nTPM]":"184.6","Tissue RNA - kidney [nTPM]":"79.4","Tissue RNA - liver [nTPM]":"126.5","Tissue RNA - lung [nTPM]":"214.5","Tissue RNA - lymph node [nTPM]":"251.3","Tissue RNA - medulla oblongata [nTPM]":"199.8","Tissue RNA - midbrain [nTPM]":"170.2","Tissue RNA - ovary [nTPM]":"147.7","Tissue RNA - pancreas [nTPM]":"64.1","Tissue RNA - parathyroid gland [nTPM]":"66.9","Tissue RNA - pituitary gland [nTPM]":"99.2","Tissue RNA - placenta [nTPM]":"241.8","Tissue RNA - pons [nTPM]":"194.8","Tissue RNA - prostate [nTPM]":"103.6","Tissue RNA - rectum [nTPM]":"64.3","Tissue RNA - retina [nTPM]":"35.6","Tissue RNA - salivary gland [nTPM]":"71.9","Tissue RNA - seminal vesicle [nTPM]":"156.9","Tissue RNA - skeletal muscle [nTPM]":"69.3","Tissue RNA - skin 1 [nTPM]":"87.0","Tissue RNA - small intestine [nTPM]":"103.0","Tissue RNA - smooth muscle [nTPM]":"154.0","Tissue RNA - spinal cord [nTPM]":"173.6","Tissue RNA - spleen [nTPM]":"262.1","Tissue RNA - stomach 1 [nTPM]":"73.6","Tissue RNA - testis [nTPM]":"69.6","Tissue RNA - thalamus [nTPM]":"173.3","Tissue RNA - thymus [nTPM]":"160.3","Tissue RNA - thyroid gland [nTPM]":"101.3","Tissue RNA - tongue [nTPM]":"89.4","Tissue RNA - tonsil [nTPM]":"170.4","Tissue RNA - urinary bladder [nTPM]":"169.7","Tissue RNA - vagina [nTPM]":"108.4","Tissue RNA - white matter [nTPM]":"193.2","Cell RNA - A-431 [nTPM]":"128.2","Cell RNA - A549 [nTPM]":"63.0","Cell RNA - AF22 [nTPM]":"186.3","Cell RNA - AN3-CA [nTPM]":"197.6","Cell RNA - ASC diff [nTPM]":"220.7","Cell RNA - ASC TERT1 [nTPM]":"277.5","Cell RNA - BEWO [nTPM]":"35.5","Cell RNA - BJ [nTPM]":"271.1","Cell RNA - BJ hTERT+ [nTPM]":"399.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"354.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"361.1","Cell RNA - CACO-2 [nTPM]":"70.4","Cell RNA - CAPAN-2 [nTPM]":"173.2","Cell RNA - Daudi [nTPM]":"149.1","Cell RNA - EFO-21 [nTPM]":"119.2","Cell RNA - fHDF\/TERT166 [nTPM]":"567.0","Cell RNA - GAMG [nTPM]":"193.4","Cell RNA - HaCaT [nTPM]":"100.1","Cell RNA - HAP1 [nTPM]":"132.8","Cell RNA - HBEC3-KT [nTPM]":"350.3","Cell RNA - HBF TERT88 [nTPM]":"222.8","Cell RNA - HDLM-2 [nTPM]":"331.2","Cell RNA - HEK 293 [nTPM]":"50.9","Cell RNA - HEL [nTPM]":"364.8","Cell RNA - HeLa [nTPM]":"158.0","Cell RNA - Hep G2 [nTPM]":"110.2","Cell RNA - HHSteC [nTPM]":"219.8","Cell RNA - HL-60 [nTPM]":"329.2","Cell RNA - HMC-1 [nTPM]":"479.8","Cell RNA - HSkMC [nTPM]":"270.3","Cell RNA - hTCEpi [nTPM]":"152.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"319.1","Cell RNA - hTERT-HME1 [nTPM]":"129.8","Cell RNA - hTERT-RPE1 [nTPM]":"289.6","Cell RNA - HUVEC TERT2 [nTPM]":"837.8","Cell RNA - JURKAT [nTPM]":"124.1","Cell RNA - K-562 [nTPM]":"26.1","Cell RNA - Karpas-707 [nTPM]":"307.1","Cell RNA - LHCN-M2 [nTPM]":"357.5","Cell RNA - MCF7 [nTPM]":"155.7","Cell RNA - MOLT-4 [nTPM]":"313.6","Cell RNA - NB-4 [nTPM]":"433.0","Cell RNA - NTERA-2 [nTPM]":"109.7","Cell RNA - OE19 [nTPM]":"59.0","Cell RNA - PC-3 [nTPM]":"302.4","Cell RNA - REH [nTPM]":"185.0","Cell RNA - RH-30 [nTPM]":"89.8","Cell RNA - RPMI-8226 [nTPM]":"219.7","Cell RNA - RPTEC TERT1 [nTPM]":"232.6","Cell RNA - RT4 [nTPM]":"130.9","Cell RNA - SCLC-21H [nTPM]":"48.4","Cell RNA - SH-SY5Y [nTPM]":"86.1","Cell RNA - SiHa [nTPM]":"189.5","Cell RNA - SK-BR-3 [nTPM]":"57.1","Cell RNA - SK-MEL-30 [nTPM]":"124.4","Cell RNA - SuSa [nTPM]":"150.4","Cell RNA - T-47d [nTPM]":"94.3","Cell RNA - THP-1 [nTPM]":"346.1","Cell RNA - TIME [nTPM]":"792.3","Cell RNA - U-138 MG [nTPM]":"330.9","Cell RNA - U-2 OS [nTPM]":"187.5","Cell RNA - U-2197 [nTPM]":"309.2","Cell RNA - U-251 MG [nTPM]":"274.7","Cell RNA - U-266\/70 [nTPM]":"199.4","Cell RNA - U-266\/84 [nTPM]":"278.3","Cell RNA - U-698 [nTPM]":"127.0","Cell RNA - U-87 MG [nTPM]":"373.6","Cell RNA - U-937 [nTPM]":"466.9","Cell RNA - WM-115 [nTPM]":"398.1","Blood RNA - basophil [nTPM]":"16.6","Blood RNA - classical monocyte [nTPM]":"59.3","Blood RNA - eosinophil [nTPM]":"113.7","Blood RNA - gdT-cell [nTPM]":"33.7","Blood RNA - intermediate monocyte [nTPM]":"80.9","Blood RNA - MAIT T-cell [nTPM]":"20.2","Blood RNA - memory B-cell [nTPM]":"28.8","Blood RNA - memory CD4 T-cell [nTPM]":"26.8","Blood RNA - memory CD8 T-cell [nTPM]":"34.3","Blood RNA - myeloid DC [nTPM]":"57.3","Blood RNA - naive B-cell [nTPM]":"26.1","Blood RNA - naive CD4 T-cell [nTPM]":"20.2","Blood RNA - naive CD8 T-cell [nTPM]":"25.8","Blood RNA - neutrophil [nTPM]":"145.2","Blood RNA - NK-cell [nTPM]":"23.5","Blood RNA - non-classical monocyte [nTPM]":"74.5","Blood RNA - plasmacytoid DC [nTPM]":"47.2","Blood RNA - T-reg [nTPM]":"34.0","Blood RNA - total PBMC [nTPM]":"27.3","Brain RNA - amygdala [nTPM]":"155.2","Brain RNA - basal ganglia [nTPM]":"167.3","Brain RNA - cerebellum [nTPM]":"166.3","Brain RNA - cerebral cortex [nTPM]":"181.6","Brain RNA - hippocampal formation [nTPM]":"144.3","Brain RNA - hypothalamus [nTPM]":"184.6","Brain RNA - medulla oblongata [nTPM]":"199.8","Brain RNA - midbrain [nTPM]":"170.2","Brain RNA - pons [nTPM]":"194.8","Brain RNA - spinal cord [nTPM]":"173.6","Brain RNA - thalamus [nTPM]":"173.3","Brain RNA - white matter [nTPM]":"193.2","Single Cell Type RNA - Adipocytes [nTPM]":"656.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.1","Single Cell Type RNA - Astrocytes [nTPM]":"25.1","Single Cell Type RNA - B-cells [nTPM]":"119.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"29.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"83.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"55.8","Single Cell Type RNA - Club cells [nTPM]":"26.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"79.5","Single Cell Type RNA - dendritic cells [nTPM]":"311.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"124.3","Single Cell Type RNA - Early spermatids [nTPM]":"203.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"57.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"115.7","Single Cell Type RNA - Endothelial cells [nTPM]":"340.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"92.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"60.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.4","Single Cell Type RNA - Fibroblasts [nTPM]":"101.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.8","Single Cell Type RNA - granulocytes [nTPM]":"89.9","Single Cell Type RNA - Granulosa cells [nTPM]":"150.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"221.3","Single Cell Type RNA - Hepatocytes [nTPM]":"79.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"336.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"342.7","Single Cell Type RNA - Langerhans cells [nTPM]":"291.7","Single Cell Type RNA - Late spermatids [nTPM]":"302.0","Single Cell Type RNA - Leydig cells [nTPM]":"90.7","Single Cell Type RNA - Macrophages [nTPM]":"386.1","Single Cell Type RNA - Melanocytes [nTPM]":"83.6","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"356.6","Single Cell Type RNA - Muller glia cells [nTPM]":"292.6","Single Cell Type RNA - NK-cells [nTPM]":"151.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"160.3","Single Cell Type RNA - Paneth cells [nTPM]":"40.9","Single Cell Type RNA - Peritubular cells [nTPM]":"95.5","Single Cell Type RNA - Plasma cells [nTPM]":"104.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.9","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"85.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"163.1","Single Cell Type RNA - Spermatocytes [nTPM]":"16.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"62.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"116.4","Single Cell Type RNA - T-cells [nTPM]":"164.9","Single Cell Type RNA - Theca cells [nTPM]":"156.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.5","Single Cell Type RNA - Urothelial cells [nTPM]":"70.1"},{"Gene":"HRAS","Gene synonym":["HRAS1"],"Ensembl":"ENSG00000174775","Gene description":"HRas proto-oncogene, GTPase","Uniprot":["P01112"],"Chromosome":"11","Position":"532242-537287","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"145.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"4.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002015","HPA049830","HPA070222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002015":null,"HPA049830":"AB_2680903","HPA070222":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.1","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"64.6","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"67.2","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"27.0","Tissue RNA - cerebellum [nTPM]":"62.1","Tissue RNA - cerebral cortex [nTPM]":"86.8","Tissue RNA - cervix [nTPM]":"30.4","Tissue RNA - choroid plexus [nTPM]":"58.3","Tissue RNA - colon [nTPM]":"34.3","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"80.1","Tissue RNA - fallopian tube [nTPM]":"18.9","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"56.8","Tissue RNA - hippocampal formation [nTPM]":"64.4","Tissue RNA - hypothalamus [nTPM]":"64.6","Tissue RNA - kidney [nTPM]":"33.8","Tissue RNA - liver [nTPM]":"21.8","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"65.6","Tissue RNA - midbrain [nTPM]":"65.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"20.5","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"38.2","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"66.9","Tissue RNA - prostate [nTPM]":"38.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"27.3","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"59.0","Tissue RNA - skin 1 [nTPM]":"69.9","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"64.2","Tissue RNA - spleen [nTPM]":"20.6","Tissue RNA - stomach 1 [nTPM]":"24.2","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"64.8","Tissue RNA - thymus [nTPM]":"9.2","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"25.2","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"34.5","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"65.4","Cell RNA - A-431 [nTPM]":"59.0","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"44.2","Cell RNA - AN3-CA [nTPM]":"25.6","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"39.6","Cell RNA - BJ [nTPM]":"49.9","Cell RNA - BJ hTERT+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.5","Cell RNA - CACO-2 [nTPM]":"62.4","Cell RNA - CAPAN-2 [nTPM]":"29.7","Cell RNA - Daudi [nTPM]":"20.4","Cell RNA - EFO-21 [nTPM]":"10.9","Cell RNA - fHDF\/TERT166 [nTPM]":"63.2","Cell RNA - GAMG [nTPM]":"60.7","Cell RNA - HaCaT [nTPM]":"43.7","Cell RNA - HAP1 [nTPM]":"46.0","Cell RNA - HBEC3-KT [nTPM]":"114.1","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"19.5","Cell RNA - HEK 293 [nTPM]":"108.4","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"43.7","Cell RNA - Hep G2 [nTPM]":"56.1","Cell RNA - HHSteC [nTPM]":"38.5","Cell RNA - HL-60 [nTPM]":"13.9","Cell RNA - HMC-1 [nTPM]":"12.0","Cell RNA - HSkMC [nTPM]":"28.3","Cell RNA - hTCEpi [nTPM]":"118.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.0","Cell RNA - hTERT-HME1 [nTPM]":"51.5","Cell RNA - hTERT-RPE1 [nTPM]":"19.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.5","Cell RNA - JURKAT [nTPM]":"34.3","Cell RNA - K-562 [nTPM]":"29.7","Cell RNA - Karpas-707 [nTPM]":"32.3","Cell RNA - LHCN-M2 [nTPM]":"40.9","Cell RNA - MCF7 [nTPM]":"110.6","Cell RNA - MOLT-4 [nTPM]":"34.0","Cell RNA - NB-4 [nTPM]":"50.5","Cell RNA - NTERA-2 [nTPM]":"26.5","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"94.5","Cell RNA - REH [nTPM]":"31.6","Cell RNA - RH-30 [nTPM]":"40.7","Cell RNA - RPMI-8226 [nTPM]":"18.2","Cell RNA - RPTEC TERT1 [nTPM]":"47.0","Cell RNA - RT4 [nTPM]":"33.2","Cell RNA - SCLC-21H [nTPM]":"87.6","Cell RNA - SH-SY5Y [nTPM]":"43.7","Cell RNA - SiHa [nTPM]":"25.5","Cell RNA - SK-BR-3 [nTPM]":"55.4","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"43.3","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"35.4","Cell RNA - U-138 MG [nTPM]":"47.3","Cell RNA - U-2 OS [nTPM]":"44.7","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"39.7","Cell RNA - U-266\/70 [nTPM]":"20.3","Cell RNA - U-266\/84 [nTPM]":"17.7","Cell RNA - U-698 [nTPM]":"15.4","Cell RNA - U-87 MG [nTPM]":"39.1","Cell RNA - U-937 [nTPM]":"17.0","Cell RNA - WM-115 [nTPM]":"38.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"64.6","Brain RNA - basal ganglia [nTPM]":"67.2","Brain RNA - cerebellum [nTPM]":"62.1","Brain RNA - cerebral cortex [nTPM]":"86.8","Brain RNA - hippocampal formation [nTPM]":"64.4","Brain RNA - hypothalamus [nTPM]":"64.6","Brain RNA - medulla oblongata [nTPM]":"65.6","Brain RNA - midbrain [nTPM]":"65.3","Brain RNA - pons [nTPM]":"66.9","Brain RNA - spinal cord [nTPM]":"64.2","Brain RNA - thalamus [nTPM]":"64.8","Brain RNA - white matter [nTPM]":"65.4","Single Cell Type RNA - Adipocytes [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.7","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"18.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"131.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"101.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.0","Single Cell Type RNA - Bipolar cells [nTPM]":"46.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"75.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"72.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"35.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.6","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.3","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.4","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"26.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"17.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.9","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"38.4","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"21.3","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"50.8","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.9","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"21.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"118.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"145.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"78.1","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"18.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.2","Single Cell Type RNA - Urothelial cells [nTPM]":"106.4"},{"Gene":"IGF2","Gene synonym":["C11orf43","FLJ44734","IGF-II"],"Ensembl":"ENSG00000167244","Gene description":"Insulin like growth factor 2","Uniprot":["P01344"],"Chromosome":"11","Position":"2129112-2141238","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Osteogenesis"],"Molecular function":["Growth factor","Hormone","Mitogen"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"placenta":"2749.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1104.3","Extravillous trophoblasts":"3196.3","Leydig cells":"3007.5","Peritubular cells":"643.9","Syncytiotrophoblasts":"1612.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"86.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"862.0","Hep G2":"600.5","LHCN-M2":"333.7","RH-30":"408.5","SH-SY5Y":"495.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007556","HPA007993"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":609000000,"Blood concentration - Conc. blood MS [pg\/L]":"1200000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA007556":"AB_2667860","HPA007993":"AB_1851474"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"99.7","Tissue RNA - adrenal gland [nTPM]":"58.4","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"32.6","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"41.8","Tissue RNA - cerebellum [nTPM]":"12.6","Tissue RNA - cerebral cortex [nTPM]":"86.0","Tissue RNA - cervix [nTPM]":"75.5","Tissue RNA - choroid plexus [nTPM]":"236.8","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"75.2","Tissue RNA - epididymis [nTPM]":"52.7","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"128.4","Tissue RNA - gallbladder [nTPM]":"34.8","Tissue RNA - heart muscle [nTPM]":"91.7","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"7.1","Tissue RNA - kidney [nTPM]":"31.8","Tissue RNA - liver [nTPM]":"305.9","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"20.2","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"117.8","Tissue RNA - pancreas [nTPM]":"37.5","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"25.4","Tissue RNA - placenta [nTPM]":"2749.2","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"11.6","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"82.1","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"14.7","Tissue RNA - spinal cord [nTPM]":"13.0","Tissue RNA - spleen [nTPM]":"14.4","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"23.7","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"12.4","Tissue RNA - tongue [nTPM]":"114.0","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"24.2","Tissue RNA - vagina [nTPM]":"23.6","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"112.8","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"862.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"7.0","Cell RNA - HBF TERT88 [nTPM]":"7.9","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"600.5","Cell RNA - HHSteC [nTPM]":"143.4","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"174.7","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"333.7","Cell RNA - MCF7 [nTPM]":"2.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"408.5","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"32.7","Cell RNA - SH-SY5Y [nTPM]":"495.6","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"83.0","Cell RNA - T-47d [nTPM]":"4.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"20.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"32.6","Brain RNA - cerebellum [nTPM]":"12.6","Brain RNA - cerebral cortex [nTPM]":"86.0","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"7.1","Brain RNA - medulla oblongata [nTPM]":"20.2","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"13.0","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"40.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1104.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"498.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3196.3","Single Cell Type RNA - Fibroblasts [nTPM]":"334.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"171.4","Single Cell Type RNA - Hepatocytes [nTPM]":"494.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"218.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"91.1","Single Cell Type RNA - Leydig cells [nTPM]":"3007.5","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"643.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1612.9","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"KRAS","Gene synonym":["KRAS1","KRAS2"],"Ensembl":"ENSG00000133703","Gene description":"KRAS proto-oncogene, GTPase","Uniprot":["P01116"],"Chromosome":"12","Position":"25205246-25250936","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Deafness","Disease variant","Ectodermal dysplasia","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049830"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"12.2","Tissue RNA - bone marrow [nTPM]":"27.8","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"22.0","Tissue RNA - duodenum [nTPM]":"14.0","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"12.0","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"15.3","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"8.7","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"23.0","Tissue RNA - retina [nTPM]":"22.7","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"7.6","Tissue RNA - skin 1 [nTPM]":"13.6","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"20.3","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"12.9","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"17.4","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"14.1","Cell RNA - ASC TERT1 [nTPM]":"19.9","Cell RNA - BEWO [nTPM]":"68.9","Cell RNA - BJ [nTPM]":"17.3","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.9","Cell RNA - CACO-2 [nTPM]":"51.5","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"38.7","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"32.0","Cell RNA - GAMG [nTPM]":"23.4","Cell RNA - HaCaT [nTPM]":"18.6","Cell RNA - HAP1 [nTPM]":"44.9","Cell RNA - HBEC3-KT [nTPM]":"17.3","Cell RNA - HBF TERT88 [nTPM]":"34.3","Cell RNA - HDLM-2 [nTPM]":"26.7","Cell RNA - HEK 293 [nTPM]":"15.0","Cell RNA - HEL [nTPM]":"37.6","Cell RNA - HeLa [nTPM]":"17.6","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"15.8","Cell RNA - HL-60 [nTPM]":"32.8","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"25.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"20.2","Cell RNA - hTERT-RPE1 [nTPM]":"33.6","Cell RNA - HUVEC TERT2 [nTPM]":"27.1","Cell RNA - JURKAT [nTPM]":"28.7","Cell RNA - K-562 [nTPM]":"28.0","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"27.6","Cell RNA - MCF7 [nTPM]":"14.1","Cell RNA - MOLT-4 [nTPM]":"46.8","Cell RNA - NB-4 [nTPM]":"56.6","Cell RNA - NTERA-2 [nTPM]":"87.6","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"43.4","Cell RNA - RH-30 [nTPM]":"39.9","Cell RNA - RPMI-8226 [nTPM]":"59.9","Cell RNA - RPTEC TERT1 [nTPM]":"27.2","Cell RNA - RT4 [nTPM]":"22.4","Cell RNA - SCLC-21H [nTPM]":"11.2","Cell RNA - SH-SY5Y [nTPM]":"32.4","Cell RNA - SiHa [nTPM]":"20.5","Cell RNA - SK-BR-3 [nTPM]":"24.9","Cell RNA - SK-MEL-30 [nTPM]":"21.8","Cell RNA - SuSa [nTPM]":"97.4","Cell RNA - T-47d [nTPM]":"28.9","Cell RNA - THP-1 [nTPM]":"26.9","Cell RNA - TIME [nTPM]":"28.1","Cell RNA - U-138 MG [nTPM]":"18.7","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"38.2","Cell RNA - U-251 MG [nTPM]":"22.0","Cell RNA - U-266\/70 [nTPM]":"16.4","Cell RNA - U-266\/84 [nTPM]":"28.5","Cell RNA - U-698 [nTPM]":"41.9","Cell RNA - U-87 MG [nTPM]":"15.4","Cell RNA - U-937 [nTPM]":"20.0","Cell RNA - WM-115 [nTPM]":"15.0","Blood RNA - basophil [nTPM]":"31.2","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"13.7","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"16.4","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"10.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"13.1","Blood RNA - myeloid DC [nTPM]":"7.9","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"13.8","Blood RNA - naive CD8 T-cell [nTPM]":"12.4","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"11.2","Blood RNA - non-classical monocyte [nTPM]":"22.4","Blood RNA - plasmacytoid DC [nTPM]":"7.8","Blood RNA - T-reg [nTPM]":"7.6","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"12.2","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"12.0","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"8.7","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"12.9","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"90.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"96.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.3","Single Cell Type RNA - Bipolar cells [nTPM]":"63.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"53.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"94.2","Single Cell Type RNA - dendritic cells [nTPM]":"66.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"161.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"77.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.8","Single Cell Type RNA - Endothelial cells [nTPM]":"77.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"78.8","Single Cell Type RNA - Erythroid cells [nTPM]":"60.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"91.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.4","Single Cell Type RNA - Fibroblasts [nTPM]":"50.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"98.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.4","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"26.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"77.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.5","Single Cell Type RNA - Horizontal cells [nTPM]":"92.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.9","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"53.9","Single Cell Type RNA - Langerhans cells [nTPM]":"83.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"40.7","Single Cell Type RNA - Macrophages [nTPM]":"75.3","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"82.9","Single Cell Type RNA - Muller glia cells [nTPM]":"41.7","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"114.2","Single Cell Type RNA - Paneth cells [nTPM]":"104.7","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"85.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"130.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"63.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.2","Single Cell Type RNA - Spermatocytes [nTPM]":"53.0","Single Cell Type RNA - Spermatogonia [nTPM]":"40.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"93.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"155.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"139.1","Single Cell Type RNA - T-cells [nTPM]":"83.0","Single Cell Type RNA - Theca cells [nTPM]":"36.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"96.7","Single Cell Type RNA - Urothelial cells [nTPM]":"176.9"},{"Gene":"MAX","Gene synonym":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"Ensembl":"ENSG00000125952","Gene description":"MYC associated factor X","Uniprot":["P61244"],"Chromosome":"14","Position":"65006174-65102695","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"390.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000328","HPA003474"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"CAB000328":"AB_2281783","HPA003474":"AB_1079317"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.1","Tissue RNA - adrenal gland [nTPM]":"36.3","Tissue RNA - amygdala [nTPM]":"57.4","Tissue RNA - appendix [nTPM]":"43.5","Tissue RNA - basal ganglia [nTPM]":"63.2","Tissue RNA - bone marrow [nTPM]":"105.1","Tissue RNA - breast [nTPM]":"41.2","Tissue RNA - cerebellum [nTPM]":"74.6","Tissue RNA - cerebral cortex [nTPM]":"62.9","Tissue RNA - cervix [nTPM]":"61.0","Tissue RNA - choroid plexus [nTPM]":"44.8","Tissue RNA - colon [nTPM]":"51.1","Tissue RNA - duodenum [nTPM]":"41.3","Tissue RNA - endometrium 1 [nTPM]":"51.1","Tissue RNA - epididymis [nTPM]":"29.2","Tissue RNA - esophagus [nTPM]":"75.8","Tissue RNA - fallopian tube [nTPM]":"67.2","Tissue RNA - gallbladder [nTPM]":"36.2","Tissue RNA - heart muscle [nTPM]":"52.8","Tissue RNA - hippocampal formation [nTPM]":"55.0","Tissue RNA - hypothalamus [nTPM]":"59.4","Tissue RNA - kidney [nTPM]":"39.5","Tissue RNA - liver [nTPM]":"36.8","Tissue RNA - lung [nTPM]":"51.6","Tissue RNA - lymph node [nTPM]":"63.7","Tissue RNA - medulla oblongata [nTPM]":"65.5","Tissue RNA - midbrain [nTPM]":"61.8","Tissue RNA - ovary [nTPM]":"56.2","Tissue RNA - pancreas [nTPM]":"29.3","Tissue RNA - parathyroid gland [nTPM]":"31.3","Tissue RNA - pituitary gland [nTPM]":"32.5","Tissue RNA - placenta [nTPM]":"39.8","Tissue RNA - pons [nTPM]":"65.0","Tissue RNA - prostate [nTPM]":"52.2","Tissue RNA - rectum [nTPM]":"31.8","Tissue RNA - retina [nTPM]":"23.6","Tissue RNA - salivary gland [nTPM]":"43.5","Tissue RNA - seminal vesicle [nTPM]":"38.7","Tissue RNA - skeletal muscle [nTPM]":"43.8","Tissue RNA - skin 1 [nTPM]":"55.3","Tissue RNA - small intestine [nTPM]":"51.7","Tissue RNA - smooth muscle [nTPM]":"39.5","Tissue RNA - spinal cord [nTPM]":"59.4","Tissue RNA - spleen [nTPM]":"66.3","Tissue RNA - stomach 1 [nTPM]":"39.4","Tissue RNA - testis [nTPM]":"21.5","Tissue RNA - thalamus [nTPM]":"62.1","Tissue RNA - thymus [nTPM]":"63.7","Tissue RNA - thyroid gland [nTPM]":"42.7","Tissue RNA - tongue [nTPM]":"54.0","Tissue RNA - tonsil [nTPM]":"55.1","Tissue RNA - urinary bladder [nTPM]":"51.3","Tissue RNA - vagina [nTPM]":"68.7","Tissue RNA - white matter [nTPM]":"65.3","Cell RNA - A-431 [nTPM]":"117.1","Cell RNA - A549 [nTPM]":"40.4","Cell RNA - AF22 [nTPM]":"27.8","Cell RNA - AN3-CA [nTPM]":"44.6","Cell RNA - ASC diff [nTPM]":"73.4","Cell RNA - ASC TERT1 [nTPM]":"58.0","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"39.9","Cell RNA - BJ hTERT+ [nTPM]":"62.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.4","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"86.7","Cell RNA - Daudi [nTPM]":"88.1","Cell RNA - EFO-21 [nTPM]":"33.1","Cell RNA - fHDF\/TERT166 [nTPM]":"48.8","Cell RNA - GAMG [nTPM]":"45.0","Cell RNA - HaCaT [nTPM]":"60.4","Cell RNA - HAP1 [nTPM]":"63.4","Cell RNA - HBEC3-KT [nTPM]":"52.7","Cell RNA - HBF TERT88 [nTPM]":"37.3","Cell RNA - HDLM-2 [nTPM]":"84.5","Cell RNA - HEK 293 [nTPM]":"40.5","Cell RNA - HEL [nTPM]":"143.4","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"32.0","Cell RNA - HHSteC [nTPM]":"90.9","Cell RNA - HL-60 [nTPM]":"56.2","Cell RNA - HMC-1 [nTPM]":"390.3","Cell RNA - HSkMC [nTPM]":"67.6","Cell RNA - hTCEpi [nTPM]":"43.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.7","Cell RNA - hTERT-HME1 [nTPM]":"54.9","Cell RNA - hTERT-RPE1 [nTPM]":"71.9","Cell RNA - HUVEC TERT2 [nTPM]":"54.9","Cell RNA - JURKAT [nTPM]":"71.8","Cell RNA - K-562 [nTPM]":"66.8","Cell RNA - Karpas-707 [nTPM]":"42.4","Cell RNA - LHCN-M2 [nTPM]":"53.1","Cell RNA - MCF7 [nTPM]":"63.9","Cell RNA - MOLT-4 [nTPM]":"140.1","Cell RNA - NB-4 [nTPM]":"217.6","Cell RNA - NTERA-2 [nTPM]":"36.3","Cell RNA - OE19 [nTPM]":"71.3","Cell RNA - PC-3 [nTPM]":"70.6","Cell RNA - REH [nTPM]":"75.2","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"47.3","Cell RNA - RPTEC TERT1 [nTPM]":"49.2","Cell RNA - RT4 [nTPM]":"38.8","Cell RNA - SCLC-21H [nTPM]":"61.8","Cell RNA - SH-SY5Y [nTPM]":"38.2","Cell RNA - SiHa [nTPM]":"49.6","Cell RNA - SK-BR-3 [nTPM]":"60.6","Cell RNA - SK-MEL-30 [nTPM]":"60.4","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"58.0","Cell RNA - THP-1 [nTPM]":"71.6","Cell RNA - TIME [nTPM]":"69.7","Cell RNA - U-138 MG [nTPM]":"47.8","Cell RNA - U-2 OS [nTPM]":"55.8","Cell RNA - U-2197 [nTPM]":"42.0","Cell RNA - U-251 MG [nTPM]":"33.6","Cell RNA - U-266\/70 [nTPM]":"50.7","Cell RNA - U-266\/84 [nTPM]":"43.6","Cell RNA - U-698 [nTPM]":"61.7","Cell RNA - U-87 MG [nTPM]":"56.9","Cell RNA - U-937 [nTPM]":"56.1","Cell RNA - WM-115 [nTPM]":"46.0","Blood RNA - basophil [nTPM]":"667.6","Blood RNA - classical monocyte [nTPM]":"141.9","Blood RNA - eosinophil [nTPM]":"540.8","Blood RNA - gdT-cell [nTPM]":"125.7","Blood RNA - intermediate monocyte [nTPM]":"126.4","Blood RNA - MAIT T-cell [nTPM]":"140.1","Blood RNA - memory B-cell [nTPM]":"115.7","Blood RNA - memory CD4 T-cell [nTPM]":"147.5","Blood RNA - memory CD8 T-cell [nTPM]":"130.5","Blood RNA - myeloid DC [nTPM]":"119.9","Blood RNA - naive B-cell [nTPM]":"114.9","Blood RNA - naive CD4 T-cell [nTPM]":"151.1","Blood RNA - naive CD8 T-cell [nTPM]":"127.9","Blood RNA - neutrophil [nTPM]":"305.1","Blood RNA - NK-cell [nTPM]":"126.9","Blood RNA - non-classical monocyte [nTPM]":"120.3","Blood RNA - plasmacytoid DC [nTPM]":"114.6","Blood RNA - T-reg [nTPM]":"194.0","Blood RNA - total PBMC [nTPM]":"314.2","Brain RNA - amygdala [nTPM]":"57.4","Brain RNA - basal ganglia [nTPM]":"63.2","Brain RNA - cerebellum [nTPM]":"74.6","Brain RNA - cerebral cortex [nTPM]":"62.9","Brain RNA - hippocampal formation [nTPM]":"55.0","Brain RNA - hypothalamus [nTPM]":"59.4","Brain RNA - medulla oblongata [nTPM]":"65.5","Brain RNA - midbrain [nTPM]":"61.8","Brain RNA - pons [nTPM]":"65.0","Brain RNA - spinal cord [nTPM]":"59.4","Brain RNA - thalamus [nTPM]":"62.1","Brain RNA - white matter [nTPM]":"65.3","Single Cell Type RNA - Adipocytes [nTPM]":"45.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"31.0","Single Cell Type RNA - B-cells [nTPM]":"74.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"170.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"126.3","Single Cell Type RNA - Bipolar cells [nTPM]":"28.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"42.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.4","Single Cell Type RNA - dendritic cells [nTPM]":"79.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"116.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"38.8","Single Cell Type RNA - Early spermatids [nTPM]":"45.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.6","Single Cell Type RNA - Endothelial cells [nTPM]":"59.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.3","Single Cell Type RNA - Erythroid cells [nTPM]":"40.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.4","Single Cell Type RNA - Fibroblasts [nTPM]":"46.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.0","Single Cell Type RNA - granulocytes [nTPM]":"62.8","Single Cell Type RNA - Granulosa cells [nTPM]":"38.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"71.0","Single Cell Type RNA - Hepatocytes [nTPM]":"23.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"59.9","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.7","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"81.8","Single Cell Type RNA - Langerhans cells [nTPM]":"66.7","Single Cell Type RNA - Late spermatids [nTPM]":"115.6","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"147.2","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"67.1","Single Cell Type RNA - Muller glia cells [nTPM]":"47.3","Single Cell Type RNA - NK-cells [nTPM]":"69.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.6","Single Cell Type RNA - Paneth cells [nTPM]":"96.7","Single Cell Type RNA - Peritubular cells [nTPM]":"60.2","Single Cell Type RNA - Plasma cells [nTPM]":"58.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"80.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"100.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.9","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"76.3","Single Cell Type RNA - Spermatocytes [nTPM]":"43.2","Single Cell Type RNA - Spermatogonia [nTPM]":"28.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"84.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"180.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"54.0","Single Cell Type RNA - T-cells [nTPM]":"83.9","Single Cell Type RNA - Theca cells [nTPM]":"25.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.7","Single Cell Type RNA - Urothelial cells [nTPM]":"76.2"},{"Gene":"MC2R","Gene synonym":["ACTHR"],"Ensembl":"ENSG00000185231","Gene description":"Melanocortin 2 receptor","Uniprot":["Q01718"],"Chromosome":"18","Position":"13882044-13915707","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"33","RNA tissue specific nTPM":{"adrenal gland":"57.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079148"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079148":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"57.9","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MEN1","Gene synonym":[],"Ensembl":"ENSG00000133895","Gene description":"Menin 1","Uniprot":["O00255"],"Chromosome":"11","Position":"64803510-64811294","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030342"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030342":"AB_10610138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"24.2","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"19.3","Tissue RNA - choroid plexus [nTPM]":"13.0","Tissue RNA - colon [nTPM]":"16.8","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"8.1","Tissue RNA - esophagus [nTPM]":"23.9","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"12.7","Tissue RNA - kidney [nTPM]":"19.4","Tissue RNA - liver [nTPM]":"30.3","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"21.7","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"24.0","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"25.5","Tissue RNA - stomach 1 [nTPM]":"20.6","Tissue RNA - testis [nTPM]":"16.3","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"24.5","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"18.7","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"30.8","Cell RNA - A549 [nTPM]":"33.7","Cell RNA - AF22 [nTPM]":"22.4","Cell RNA - AN3-CA [nTPM]":"37.7","Cell RNA - ASC diff [nTPM]":"30.4","Cell RNA - ASC TERT1 [nTPM]":"17.4","Cell RNA - BEWO [nTPM]":"24.8","Cell RNA - BJ [nTPM]":"19.2","Cell RNA - BJ hTERT+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.2","Cell RNA - CACO-2 [nTPM]":"19.0","Cell RNA - CAPAN-2 [nTPM]":"25.5","Cell RNA - Daudi [nTPM]":"43.6","Cell RNA - EFO-21 [nTPM]":"33.8","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"29.8","Cell RNA - HaCaT [nTPM]":"39.0","Cell RNA - HAP1 [nTPM]":"36.4","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"30.5","Cell RNA - HEK 293 [nTPM]":"48.1","Cell RNA - HEL [nTPM]":"35.6","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"30.9","Cell RNA - HHSteC [nTPM]":"27.2","Cell RNA - HL-60 [nTPM]":"23.6","Cell RNA - HMC-1 [nTPM]":"22.8","Cell RNA - HSkMC [nTPM]":"19.2","Cell RNA - hTCEpi [nTPM]":"18.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.8","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.5","Cell RNA - HUVEC TERT2 [nTPM]":"33.7","Cell RNA - JURKAT [nTPM]":"49.3","Cell RNA - K-562 [nTPM]":"51.5","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"54.2","Cell RNA - MOLT-4 [nTPM]":"60.3","Cell RNA - NB-4 [nTPM]":"29.3","Cell RNA - NTERA-2 [nTPM]":"36.7","Cell RNA - OE19 [nTPM]":"30.3","Cell RNA - PC-3 [nTPM]":"54.7","Cell RNA - REH [nTPM]":"45.1","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"23.2","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"33.6","Cell RNA - SH-SY5Y [nTPM]":"28.9","Cell RNA - SiHa [nTPM]":"26.0","Cell RNA - SK-BR-3 [nTPM]":"36.9","Cell RNA - SK-MEL-30 [nTPM]":"27.9","Cell RNA - SuSa [nTPM]":"16.5","Cell RNA - T-47d [nTPM]":"56.6","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"17.4","Cell RNA - U-138 MG [nTPM]":"23.5","Cell RNA - U-2 OS [nTPM]":"28.8","Cell RNA - U-2197 [nTPM]":"36.5","Cell RNA - U-251 MG [nTPM]":"16.7","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"22.1","Cell RNA - U-87 MG [nTPM]":"25.5","Cell RNA - U-937 [nTPM]":"16.2","Cell RNA - WM-115 [nTPM]":"21.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"12.7","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"10.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"14.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"NCOA4","Gene synonym":["ARA70","DKFZp762E1112","ELE1","PTC3","RFG"],"Ensembl":"ENSG00000266412","Gene description":"Nuclear receptor coactivator 4","Uniprot":["Q13772"],"Chromosome":"10","Position":"46005088-46030623","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"476.2","Macrophages":"316.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"251.9","granulocytes":"839.6","monocytes":"363.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051260","HPA065208"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA051260":"AB_2681412","HPA065208":"AB_2685432"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Tissue RNA - adipose tissue [nTPM]":"117.1","Tissue RNA - adrenal gland [nTPM]":"67.8","Tissue RNA - amygdala [nTPM]":"45.6","Tissue RNA - appendix [nTPM]":"91.5","Tissue RNA - basal ganglia [nTPM]":"52.5","Tissue RNA - bone marrow [nTPM]":"189.5","Tissue RNA - breast [nTPM]":"96.9","Tissue RNA - cerebellum [nTPM]":"56.1","Tissue RNA - cerebral cortex [nTPM]":"50.9","Tissue RNA - cervix [nTPM]":"85.1","Tissue RNA - choroid plexus [nTPM]":"50.7","Tissue RNA - colon [nTPM]":"110.3","Tissue RNA - duodenum [nTPM]":"249.7","Tissue RNA - endometrium 1 [nTPM]":"70.2","Tissue RNA - epididymis [nTPM]":"74.6","Tissue RNA - esophagus [nTPM]":"110.3","Tissue RNA - fallopian tube [nTPM]":"62.6","Tissue RNA - gallbladder [nTPM]":"87.8","Tissue RNA - heart muscle [nTPM]":"156.8","Tissue RNA - hippocampal formation [nTPM]":"40.6","Tissue RNA - hypothalamus [nTPM]":"55.8","Tissue RNA - kidney [nTPM]":"159.7","Tissue RNA - liver [nTPM]":"372.9","Tissue RNA - lung [nTPM]":"108.3","Tissue RNA - lymph node [nTPM]":"102.6","Tissue RNA - medulla oblongata [nTPM]":"52.4","Tissue RNA - midbrain [nTPM]":"53.5","Tissue RNA - ovary [nTPM]":"65.5","Tissue RNA - pancreas [nTPM]":"64.6","Tissue RNA - parathyroid gland [nTPM]":"97.9","Tissue RNA - pituitary gland [nTPM]":"25.2","Tissue RNA - placenta [nTPM]":"131.3","Tissue RNA - pons [nTPM]":"53.6","Tissue RNA - prostate [nTPM]":"132.2","Tissue RNA - rectum [nTPM]":"115.7","Tissue RNA - retina [nTPM]":"33.7","Tissue RNA - salivary gland [nTPM]":"79.2","Tissue RNA - seminal vesicle [nTPM]":"78.7","Tissue RNA - skeletal muscle [nTPM]":"163.5","Tissue RNA - skin 1 [nTPM]":"71.1","Tissue RNA - small intestine [nTPM]":"155.9","Tissue RNA - smooth muscle [nTPM]":"98.3","Tissue RNA - spinal cord [nTPM]":"52.6","Tissue RNA - spleen [nTPM]":"148.1","Tissue RNA - stomach 1 [nTPM]":"90.3","Tissue RNA - testis [nTPM]":"43.6","Tissue RNA - thalamus [nTPM]":"51.6","Tissue RNA - thymus [nTPM]":"124.4","Tissue RNA - thyroid gland [nTPM]":"87.0","Tissue RNA - tongue [nTPM]":"193.6","Tissue RNA - tonsil [nTPM]":"150.3","Tissue RNA - urinary bladder [nTPM]":"104.6","Tissue RNA - vagina [nTPM]":"46.8","Tissue RNA - white matter [nTPM]":"60.0","Cell RNA - A-431 [nTPM]":"142.7","Cell RNA - A549 [nTPM]":"58.5","Cell RNA - AF22 [nTPM]":"68.0","Cell RNA - AN3-CA [nTPM]":"70.4","Cell RNA - ASC diff [nTPM]":"176.9","Cell RNA - ASC TERT1 [nTPM]":"159.4","Cell RNA - BEWO [nTPM]":"170.3","Cell RNA - BJ [nTPM]":"128.3","Cell RNA - BJ hTERT+ [nTPM]":"204.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"122.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.6","Cell RNA - CACO-2 [nTPM]":"91.0","Cell RNA - CAPAN-2 [nTPM]":"102.3","Cell RNA - Daudi [nTPM]":"161.2","Cell RNA - EFO-21 [nTPM]":"149.2","Cell RNA - fHDF\/TERT166 [nTPM]":"211.2","Cell RNA - GAMG [nTPM]":"69.1","Cell RNA - HaCaT [nTPM]":"141.8","Cell RNA - HAP1 [nTPM]":"72.6","Cell RNA - HBEC3-KT [nTPM]":"142.3","Cell RNA - HBF TERT88 [nTPM]":"137.1","Cell RNA - HDLM-2 [nTPM]":"114.4","Cell RNA - HEK 293 [nTPM]":"74.1","Cell RNA - HEL [nTPM]":"108.4","Cell RNA - HeLa [nTPM]":"74.3","Cell RNA - Hep G2 [nTPM]":"263.5","Cell RNA - HHSteC [nTPM]":"124.0","Cell RNA - HL-60 [nTPM]":"279.9","Cell RNA - HMC-1 [nTPM]":"229.7","Cell RNA - HSkMC [nTPM]":"156.1","Cell RNA - hTCEpi [nTPM]":"139.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"104.2","Cell RNA - hTERT-HME1 [nTPM]":"175.7","Cell RNA - hTERT-RPE1 [nTPM]":"131.6","Cell RNA - HUVEC TERT2 [nTPM]":"185.5","Cell RNA - JURKAT [nTPM]":"79.5","Cell RNA - K-562 [nTPM]":"119.7","Cell RNA - Karpas-707 [nTPM]":"93.5","Cell RNA - LHCN-M2 [nTPM]":"171.9","Cell RNA - MCF7 [nTPM]":"64.0","Cell RNA - MOLT-4 [nTPM]":"136.1","Cell RNA - NB-4 [nTPM]":"104.3","Cell RNA - NTERA-2 [nTPM]":"41.4","Cell RNA - OE19 [nTPM]":"110.2","Cell RNA - PC-3 [nTPM]":"34.8","Cell RNA - REH [nTPM]":"79.5","Cell RNA - RH-30 [nTPM]":"99.3","Cell RNA - RPMI-8226 [nTPM]":"96.7","Cell RNA - RPTEC TERT1 [nTPM]":"148.9","Cell RNA - RT4 [nTPM]":"119.4","Cell RNA - SCLC-21H [nTPM]":"68.2","Cell RNA - SH-SY5Y [nTPM]":"46.1","Cell RNA - SiHa [nTPM]":"128.9","Cell RNA - SK-BR-3 [nTPM]":"146.2","Cell RNA - SK-MEL-30 [nTPM]":"131.5","Cell RNA - SuSa [nTPM]":"133.5","Cell RNA - T-47d [nTPM]":"105.7","Cell RNA - THP-1 [nTPM]":"135.3","Cell RNA - TIME [nTPM]":"171.6","Cell RNA - U-138 MG [nTPM]":"75.8","Cell RNA - U-2 OS [nTPM]":"89.9","Cell RNA - U-2197 [nTPM]":"81.3","Cell RNA - U-251 MG [nTPM]":"87.5","Cell RNA - U-266\/70 [nTPM]":"69.3","Cell RNA - U-266\/84 [nTPM]":"79.1","Cell RNA - U-698 [nTPM]":"156.9","Cell RNA - U-87 MG [nTPM]":"94.6","Cell RNA - U-937 [nTPM]":"231.2","Cell RNA - WM-115 [nTPM]":"41.2","Blood RNA - basophil [nTPM]":"692.1","Blood RNA - classical monocyte [nTPM]":"363.6","Blood RNA - eosinophil [nTPM]":"611.8","Blood RNA - gdT-cell [nTPM]":"78.9","Blood RNA - intermediate monocyte [nTPM]":"223.6","Blood RNA - MAIT T-cell [nTPM]":"86.2","Blood RNA - memory B-cell [nTPM]":"57.6","Blood RNA - memory CD4 T-cell [nTPM]":"73.3","Blood RNA - memory CD8 T-cell [nTPM]":"74.9","Blood RNA - myeloid DC [nTPM]":"251.9","Blood RNA - naive B-cell [nTPM]":"53.8","Blood RNA - naive CD4 T-cell [nTPM]":"78.2","Blood RNA - naive CD8 T-cell [nTPM]":"66.4","Blood RNA - neutrophil [nTPM]":"839.6","Blood RNA - NK-cell [nTPM]":"119.0","Blood RNA - non-classical monocyte [nTPM]":"275.3","Blood RNA - plasmacytoid DC [nTPM]":"77.4","Blood RNA - T-reg [nTPM]":"92.8","Blood RNA - total PBMC [nTPM]":"559.4","Brain RNA - amygdala [nTPM]":"45.6","Brain RNA - basal ganglia [nTPM]":"52.5","Brain RNA - cerebellum [nTPM]":"56.1","Brain RNA - cerebral cortex [nTPM]":"50.9","Brain RNA - hippocampal formation [nTPM]":"40.6","Brain RNA - hypothalamus [nTPM]":"55.8","Brain RNA - medulla oblongata [nTPM]":"52.4","Brain RNA - midbrain [nTPM]":"53.5","Brain RNA - pons [nTPM]":"53.6","Brain RNA - spinal cord [nTPM]":"52.6","Brain RNA - thalamus [nTPM]":"51.6","Brain RNA - white matter [nTPM]":"60.0","Single Cell Type RNA - Adipocytes [nTPM]":"44.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"95.2","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"44.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"49.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"126.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Bipolar cells [nTPM]":"14.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"161.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"96.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"104.7","Single Cell Type RNA - dendritic cells [nTPM]":"58.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"108.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"45.3","Single Cell Type RNA - Early spermatids [nTPM]":"105.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.7","Single Cell Type RNA - Endothelial cells [nTPM]":"52.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.9","Single Cell Type RNA - Erythroid cells [nTPM]":"476.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"107.2","Single Cell Type RNA - Fibroblasts [nTPM]":"45.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"56.9","Single Cell Type RNA - granulocytes [nTPM]":"195.2","Single Cell Type RNA - Granulosa cells [nTPM]":"28.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.3","Single Cell Type RNA - Hepatocytes [nTPM]":"166.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"181.4","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.4","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"254.5","Single Cell Type RNA - Langerhans cells [nTPM]":"74.2","Single Cell Type RNA - Late spermatids [nTPM]":"72.4","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"316.1","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"158.4","Single Cell Type RNA - Muller glia cells [nTPM]":"38.2","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.8","Single Cell Type RNA - Paneth cells [nTPM]":"63.9","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"37.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"62.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"162.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"128.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.5","Single Cell Type RNA - Spermatogonia [nTPM]":"16.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"71.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"158.2","Single Cell Type RNA - T-cells [nTPM]":"41.3","Single Cell Type RNA - Theca cells [nTPM]":"60.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"71.3","Single Cell Type RNA - Urothelial cells [nTPM]":"52.0"},{"Gene":"NF1","Gene synonym":[],"Ensembl":"ENSG00000196712","Gene description":"Neurofibromin 1","Uniprot":["P21359"],"Chromosome":"17","Position":"31094927-31382116","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"254.0","Excitatory neurons":"325.3","Inhibitory neurons":"412.5","Oligodendrocyte precursor cells":"428.2","Oligodendrocytes":"317.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045502"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA045502":"AB_2679352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"12.2","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"9.0","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"11.3","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"10.4","Tissue RNA - parathyroid gland [nTPM]":"15.9","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"8.8","Tissue RNA - retina [nTPM]":"20.9","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"9.5","Tissue RNA - skeletal muscle [nTPM]":"8.1","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"19.5","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"15.8","Cell RNA - A549 [nTPM]":"20.3","Cell RNA - AF22 [nTPM]":"24.2","Cell RNA - AN3-CA [nTPM]":"13.1","Cell RNA - ASC diff [nTPM]":"20.1","Cell RNA - ASC TERT1 [nTPM]":"25.8","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.8","Cell RNA - CACO-2 [nTPM]":"18.4","Cell RNA - CAPAN-2 [nTPM]":"10.5","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.1","Cell RNA - GAMG [nTPM]":"22.9","Cell RNA - HaCaT [nTPM]":"26.8","Cell RNA - HAP1 [nTPM]":"22.2","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"32.6","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"13.4","Cell RNA - HeLa [nTPM]":"18.8","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"14.2","Cell RNA - HL-60 [nTPM]":"24.4","Cell RNA - HMC-1 [nTPM]":"10.6","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"11.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.8","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"9.5","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"19.8","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"18.8","Cell RNA - MCF7 [nTPM]":"12.4","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"36.8","Cell RNA - RPMI-8226 [nTPM]":"12.3","Cell RNA - RPTEC TERT1 [nTPM]":"14.7","Cell RNA - RT4 [nTPM]":"22.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"25.4","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"25.0","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"14.1","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"18.8","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"13.2","Cell RNA - U-266\/84 [nTPM]":"6.9","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"10.0","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"12.2","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"30.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.1","Single Cell Type RNA - Astrocytes [nTPM]":"254.0","Single Cell Type RNA - B-cells [nTPM]":"18.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"62.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"29.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"137.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.5","Single Cell Type RNA - dendritic cells [nTPM]":"23.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"210.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"325.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"39.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.8","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"44.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"35.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.5","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"412.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.3","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"27.6","Single Cell Type RNA - Langerhans cells [nTPM]":"34.1","Single Cell Type RNA - Late spermatids [nTPM]":"94.6","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"28.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"215.5","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"47.5","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"428.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"317.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.3","Single Cell Type RNA - Paneth cells [nTPM]":"43.0","Single Cell Type RNA - Peritubular cells [nTPM]":"50.4","Single Cell Type RNA - Plasma cells [nTPM]":"30.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.3","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"28.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.3","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"36.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.4","Single Cell Type RNA - Urothelial cells [nTPM]":"64.5"},{"Gene":"NRAS","Gene synonym":["N-ras"],"Ensembl":"ENSG00000213281","Gene description":"NRAS proto-oncogene, GTPase","Uniprot":["P01111"],"Chromosome":"1","Position":"114704469-114716771","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010157","HPA049830","CAB079912"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010157":"AB_632073","CAB079912":"AB_2784586","HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.0","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"25.7","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"58.5","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"27.8","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"12.4","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"24.9","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"30.4","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"28.3","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"11.4","Tissue RNA - rectum [nTPM]":"26.6","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"21.8","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"39.0","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"93.7","Cell RNA - A549 [nTPM]":"24.9","Cell RNA - AF22 [nTPM]":"65.2","Cell RNA - AN3-CA [nTPM]":"24.9","Cell RNA - ASC diff [nTPM]":"26.4","Cell RNA - ASC TERT1 [nTPM]":"56.3","Cell RNA - BEWO [nTPM]":"46.5","Cell RNA - BJ [nTPM]":"43.5","Cell RNA - BJ hTERT+ [nTPM]":"48.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.0","Cell RNA - CACO-2 [nTPM]":"50.4","Cell RNA - CAPAN-2 [nTPM]":"33.9","Cell RNA - Daudi [nTPM]":"70.4","Cell RNA - EFO-21 [nTPM]":"56.3","Cell RNA - fHDF\/TERT166 [nTPM]":"58.9","Cell RNA - GAMG [nTPM]":"55.4","Cell RNA - HaCaT [nTPM]":"26.0","Cell RNA - HAP1 [nTPM]":"88.2","Cell RNA - HBEC3-KT [nTPM]":"70.6","Cell RNA - HBF TERT88 [nTPM]":"113.4","Cell RNA - HDLM-2 [nTPM]":"96.5","Cell RNA - HEK 293 [nTPM]":"34.2","Cell RNA - HEL [nTPM]":"47.8","Cell RNA - HeLa [nTPM]":"34.5","Cell RNA - Hep G2 [nTPM]":"60.2","Cell RNA - HHSteC [nTPM]":"52.3","Cell RNA - HL-60 [nTPM]":"120.0","Cell RNA - HMC-1 [nTPM]":"71.0","Cell RNA - HSkMC [nTPM]":"51.1","Cell RNA - hTCEpi [nTPM]":"56.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.5","Cell RNA - hTERT-HME1 [nTPM]":"66.2","Cell RNA - hTERT-RPE1 [nTPM]":"25.0","Cell RNA - HUVEC TERT2 [nTPM]":"102.8","Cell RNA - JURKAT [nTPM]":"54.6","Cell RNA - K-562 [nTPM]":"77.3","Cell RNA - Karpas-707 [nTPM]":"78.5","Cell RNA - LHCN-M2 [nTPM]":"71.0","Cell RNA - MCF7 [nTPM]":"248.9","Cell RNA - MOLT-4 [nTPM]":"83.5","Cell RNA - NB-4 [nTPM]":"46.4","Cell RNA - NTERA-2 [nTPM]":"111.0","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"62.9","Cell RNA - RH-30 [nTPM]":"116.0","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"70.6","Cell RNA - RT4 [nTPM]":"49.5","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"59.0","Cell RNA - SiHa [nTPM]":"44.7","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"107.1","Cell RNA - SuSa [nTPM]":"75.4","Cell RNA - T-47d [nTPM]":"31.9","Cell RNA - THP-1 [nTPM]":"96.2","Cell RNA - TIME [nTPM]":"79.2","Cell RNA - U-138 MG [nTPM]":"43.3","Cell RNA - U-2 OS [nTPM]":"82.2","Cell RNA - U-2197 [nTPM]":"81.5","Cell RNA - U-251 MG [nTPM]":"90.3","Cell RNA - U-266\/70 [nTPM]":"137.7","Cell RNA - U-266\/84 [nTPM]":"101.6","Cell RNA - U-698 [nTPM]":"81.6","Cell RNA - U-87 MG [nTPM]":"86.4","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"159.0","Blood RNA - basophil [nTPM]":"38.7","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"12.6","Blood RNA - gdT-cell [nTPM]":"11.7","Blood RNA - intermediate monocyte [nTPM]":"19.2","Blood RNA - MAIT T-cell [nTPM]":"10.5","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"12.9","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"15.5","Blood RNA - non-classical monocyte [nTPM]":"17.6","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"25.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - dendritic cells [nTPM]":"27.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.6","Single Cell Type RNA - Erythroid cells [nTPM]":"31.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.4","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.0","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"22.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"29.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.1","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"44.9","Single Cell Type RNA - Langerhans cells [nTPM]":"30.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"30.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"41.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.4","Single Cell Type RNA - Paneth cells [nTPM]":"32.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"39.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"21.9","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.8","Single Cell Type RNA - Urothelial cells [nTPM]":"40.2"},{"Gene":"NTRK1","Gene synonym":["MTC","TRK","TRKA"],"Ensembl":"ENSG00000198400","Gene description":"Neurotrophic receptor tyrosine kinase 1","Uniprot":["P04629"],"Chromosome":"1","Position":"156815640-156881850","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"7.0","brain":"21.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Bipolar cells":"22.8","granulocytes":"55.9","Horizontal cells":"57.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"7.6","medulla oblongata":"19.8","pons":"21.7"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"116","RNA blood cell specific nTPM":{"basophil":"94.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"768","RNA blood lineage specific nTPM":{"granulocytes":"94.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HMC-1":"82.1"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"8.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"4.1"},"Antibody":["CAB004606","HPA035799","HPA076570"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"79000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004606":"AB_628397","HPA035799":"AB_2674788","HPA076570":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"21.7","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"11.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"14.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"82.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"4.4","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"2.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"94.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"21.7","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"55.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PAX8","Gene synonym":[],"Ensembl":"ENSG00000125618","Gene description":"Paired box 8","Uniprot":["Q06710"],"Chromosome":"2","Position":"113215997-113278921","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"kidney":"267.9","thyroid gland":"565.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"246.5","Endometrial ciliated cells":"114.0","Glandular and luminal cells":"228.2","Proximal tubular cells":"128.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"endometrial cancer":"60.6","ovarian cancer":"63.5","renal cancer":"33.2","thyroid cancer":"122.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"EFO-21":"79.7","GAMG":"50.0","RPTEC TERT1":"193.2"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"pons and medulla":"5.5"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030062","CAB055097","CAB061888","HPA064554"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB055097":"AB_2236705","CAB061888":"AB_10895719","HPA030062":"AB_10603982","HPA064554":"AB_2685283"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"1.8","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"32.9","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"37.5","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"267.9","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"26.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"565.5","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"9.4","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"8.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"1.7","Cell RNA - EFO-21 [nTPM]":"79.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"50.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"3.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"9.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"6.2","Cell RNA - LHCN-M2 [nTPM]":"2.5","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"193.2","Cell RNA - RT4 [nTPM]":"14.4","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"10.4","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"2.7","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"7.2","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"11.9","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"246.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"114.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"228.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"128.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"PPARG","Gene synonym":["NR1C3","PPARG1","PPARG2","PPARgamma"],"Ensembl":"ENSG00000132170","Gene description":"Peroxisome proliferator activated receptor gamma","Uniprot":["P37231"],"Chromosome":"3","Position":"12287368-12434356","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Nuclear receptors","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"165.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"284.1","Extravillous trophoblasts":"217.8","Granulosa cells":"232.9","Urothelial cells":"239.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"33.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"198.7","ASC TERT1":"113.7","BEWO":"247.5","CAPAN-2":"111.6","HSkMC":"118.9","PC-3":"112.0","RT4":"157.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004282","HPA051239","HPA063663"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB004282":"AB_628115","HPA051239":"AB_2681400","HPA063663":"AB_2685081"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.52e-5"},"Tissue RNA - adipose tissue [nTPM]":"165.1","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"74.3","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"48.7","Tissue RNA - duodenum [nTPM]":"23.6","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"6.2","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"14.6","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"14.3","Tissue RNA - liver [nTPM]":"17.1","Tissue RNA - lung [nTPM]":"28.5","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"14.5","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"43.6","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"40.6","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"15.1","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"8.1","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"67.7","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"44.0","Cell RNA - A549 [nTPM]":"38.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"198.7","Cell RNA - ASC TERT1 [nTPM]":"113.7","Cell RNA - BEWO [nTPM]":"247.5","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"7.8","Cell RNA - CAPAN-2 [nTPM]":"111.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"72.9","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"14.4","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"106.4","Cell RNA - HEK 293 [nTPM]":"20.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"51.8","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"118.9","Cell RNA - hTCEpi [nTPM]":"9.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.8","Cell RNA - hTERT-HME1 [nTPM]":"37.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"8.3","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"99.2","Cell RNA - PC-3 [nTPM]":"112.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"30.6","Cell RNA - RT4 [nTPM]":"157.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"18.8","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"6.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"34.2","Cell RNA - TIME [nTPM]":"35.0","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"4.6","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"3.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"284.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"110.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"93.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"217.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"83.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.8","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"232.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"19.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"19.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.3","Single Cell Type RNA - Paneth cells [nTPM]":"84.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"22.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.9","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"239.6"},{"Gene":"RET","Gene synonym":["CDHF12","CDHR16","HSCR1","MEN2A","MEN2B","MTC1","PTC","RET51"],"Ensembl":"ENSG00000165731","Gene description":"Ret proto-oncogene","Uniprot":["P07949"],"Chromosome":"10","Position":"43077064-43130351","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Hirschsprung disease","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"20.8","brain":"27.3","parathyroid gland":"31.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"79.1","Ionocytes":"26.4","Skeletal myocytes":"23.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"74.6","NB-4":"42.2","SH-SY5Y":"329.3","THP-1":"95.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"53.3","spinal cord":"19.4"},"Antibody":["CAB002581","HPA008356","HPA008495"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB002581":"AB_563673","HPA008356":"AB_1847232","HPA008495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"27.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"31.8","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"7.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"74.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"42.2","Cell RNA - NTERA-2 [nTPM]":"7.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"329.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"95.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"27.3","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"SDHB","Gene synonym":["SDH","SDH1"],"Ensembl":"ENSG00000117118","Gene description":"Succinate dehydrogenase complex iron sulfur subunit B","Uniprot":["P21912"],"Chromosome":"1","Position":"17018722-17054032","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"491.5","tongue":"580.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"405.5","Proximal tubular cells":"449.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002868","CAB009822","CAB068233","CAB068234","CAB068235"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7900","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB009822":"AB_2183458","CAB068233":"AB_2665638","CAB068234":"AB_2665639","CAB068235":"AB_2665640","HPA002868":"AB_1079889"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"85.8","Tissue RNA - adrenal gland [nTPM]":"95.7","Tissue RNA - amygdala [nTPM]":"68.0","Tissue RNA - appendix [nTPM]":"59.0","Tissue RNA - basal ganglia [nTPM]":"72.2","Tissue RNA - bone marrow [nTPM]":"94.6","Tissue RNA - breast [nTPM]":"68.7","Tissue RNA - cerebellum [nTPM]":"80.6","Tissue RNA - cerebral cortex [nTPM]":"84.3","Tissue RNA - cervix [nTPM]":"56.8","Tissue RNA - choroid plexus [nTPM]":"81.1","Tissue RNA - colon [nTPM]":"134.3","Tissue RNA - duodenum [nTPM]":"163.0","Tissue RNA - endometrium 1 [nTPM]":"56.0","Tissue RNA - epididymis [nTPM]":"71.0","Tissue RNA - esophagus [nTPM]":"77.4","Tissue RNA - fallopian tube [nTPM]":"59.8","Tissue RNA - gallbladder [nTPM]":"48.0","Tissue RNA - heart muscle [nTPM]":"302.8","Tissue RNA - hippocampal formation [nTPM]":"69.9","Tissue RNA - hypothalamus [nTPM]":"76.9","Tissue RNA - kidney [nTPM]":"228.0","Tissue RNA - liver [nTPM]":"336.1","Tissue RNA - lung [nTPM]":"56.1","Tissue RNA - lymph node [nTPM]":"75.3","Tissue RNA - medulla oblongata [nTPM]":"74.8","Tissue RNA - midbrain [nTPM]":"71.4","Tissue RNA - ovary [nTPM]":"44.4","Tissue RNA - pancreas [nTPM]":"80.3","Tissue RNA - parathyroid gland [nTPM]":"144.3","Tissue RNA - pituitary gland [nTPM]":"42.8","Tissue RNA - placenta [nTPM]":"57.6","Tissue RNA - pons [nTPM]":"73.8","Tissue RNA - prostate [nTPM]":"55.7","Tissue RNA - rectum [nTPM]":"132.4","Tissue RNA - retina [nTPM]":"62.9","Tissue RNA - salivary gland [nTPM]":"74.0","Tissue RNA - seminal vesicle [nTPM]":"60.5","Tissue RNA - skeletal muscle [nTPM]":"491.5","Tissue RNA - skin 1 [nTPM]":"55.6","Tissue RNA - small intestine [nTPM]":"121.9","Tissue RNA - smooth muscle [nTPM]":"70.4","Tissue RNA - spinal cord [nTPM]":"73.9","Tissue RNA - spleen [nTPM]":"60.5","Tissue RNA - stomach 1 [nTPM]":"92.8","Tissue RNA - testis [nTPM]":"64.4","Tissue RNA - thalamus [nTPM]":"74.9","Tissue RNA - thymus [nTPM]":"62.7","Tissue RNA - thyroid gland [nTPM]":"64.3","Tissue RNA - tongue [nTPM]":"580.6","Tissue RNA - tonsil [nTPM]":"84.2","Tissue RNA - urinary bladder [nTPM]":"71.3","Tissue RNA - vagina [nTPM]":"52.0","Tissue RNA - white matter [nTPM]":"78.9","Cell RNA - A-431 [nTPM]":"157.3","Cell RNA - A549 [nTPM]":"152.7","Cell RNA - AF22 [nTPM]":"72.2","Cell RNA - AN3-CA [nTPM]":"107.8","Cell RNA - ASC diff [nTPM]":"141.6","Cell RNA - ASC TERT1 [nTPM]":"135.2","Cell RNA - BEWO [nTPM]":"95.9","Cell RNA - BJ [nTPM]":"122.4","Cell RNA - BJ hTERT+ [nTPM]":"145.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"254.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"227.7","Cell RNA - CACO-2 [nTPM]":"216.8","Cell RNA - CAPAN-2 [nTPM]":"183.1","Cell RNA - Daudi [nTPM]":"206.8","Cell RNA - EFO-21 [nTPM]":"159.3","Cell RNA - fHDF\/TERT166 [nTPM]":"156.4","Cell RNA - GAMG [nTPM]":"176.1","Cell RNA - HaCaT [nTPM]":"180.1","Cell RNA - HAP1 [nTPM]":"290.7","Cell RNA - HBEC3-KT [nTPM]":"226.8","Cell RNA - HBF TERT88 [nTPM]":"284.8","Cell RNA - HDLM-2 [nTPM]":"128.7","Cell RNA - HEK 293 [nTPM]":"280.6","Cell RNA - HEL [nTPM]":"183.4","Cell RNA - HeLa [nTPM]":"149.2","Cell RNA - Hep G2 [nTPM]":"168.2","Cell RNA - HHSteC [nTPM]":"172.8","Cell RNA - HL-60 [nTPM]":"276.0","Cell RNA - HMC-1 [nTPM]":"135.6","Cell RNA - HSkMC [nTPM]":"140.4","Cell RNA - hTCEpi [nTPM]":"154.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"224.5","Cell RNA - hTERT-HME1 [nTPM]":"370.1","Cell RNA - hTERT-RPE1 [nTPM]":"138.7","Cell RNA - HUVEC TERT2 [nTPM]":"183.6","Cell RNA - JURKAT [nTPM]":"176.5","Cell RNA - K-562 [nTPM]":"165.2","Cell RNA - Karpas-707 [nTPM]":"236.9","Cell RNA - LHCN-M2 [nTPM]":"179.6","Cell RNA - MCF7 [nTPM]":"129.5","Cell RNA - MOLT-4 [nTPM]":"182.4","Cell RNA - NB-4 [nTPM]":"175.1","Cell RNA - NTERA-2 [nTPM]":"70.4","Cell RNA - OE19 [nTPM]":"224.6","Cell RNA - PC-3 [nTPM]":"302.6","Cell RNA - REH [nTPM]":"146.1","Cell RNA - RH-30 [nTPM]":"142.5","Cell RNA - RPMI-8226 [nTPM]":"265.4","Cell RNA - RPTEC TERT1 [nTPM]":"252.4","Cell RNA - RT4 [nTPM]":"88.7","Cell RNA - SCLC-21H [nTPM]":"157.5","Cell RNA - SH-SY5Y [nTPM]":"86.0","Cell RNA - SiHa [nTPM]":"172.3","Cell RNA - SK-BR-3 [nTPM]":"216.3","Cell RNA - SK-MEL-30 [nTPM]":"392.3","Cell RNA - SuSa [nTPM]":"76.4","Cell RNA - T-47d [nTPM]":"131.1","Cell RNA - THP-1 [nTPM]":"169.1","Cell RNA - TIME [nTPM]":"94.9","Cell RNA - U-138 MG [nTPM]":"115.8","Cell RNA - U-2 OS [nTPM]":"131.0","Cell RNA - U-2197 [nTPM]":"206.4","Cell RNA - U-251 MG [nTPM]":"176.0","Cell RNA - U-266\/70 [nTPM]":"98.9","Cell RNA - U-266\/84 [nTPM]":"133.3","Cell RNA - U-698 [nTPM]":"198.6","Cell RNA - U-87 MG [nTPM]":"170.4","Cell RNA - U-937 [nTPM]":"438.5","Cell RNA - WM-115 [nTPM]":"128.3","Blood RNA - basophil [nTPM]":"68.7","Blood RNA - classical monocyte [nTPM]":"149.8","Blood RNA - eosinophil [nTPM]":"149.5","Blood RNA - gdT-cell [nTPM]":"71.4","Blood RNA - intermediate monocyte [nTPM]":"206.5","Blood RNA - MAIT T-cell [nTPM]":"70.7","Blood RNA - memory B-cell [nTPM]":"89.9","Blood RNA - memory CD4 T-cell [nTPM]":"81.0","Blood RNA - memory CD8 T-cell [nTPM]":"77.5","Blood RNA - myeloid DC [nTPM]":"186.8","Blood RNA - naive B-cell [nTPM]":"81.1","Blood RNA - naive CD4 T-cell [nTPM]":"73.5","Blood RNA - naive CD8 T-cell [nTPM]":"74.8","Blood RNA - neutrophil [nTPM]":"174.3","Blood RNA - NK-cell [nTPM]":"85.3","Blood RNA - non-classical monocyte [nTPM]":"185.7","Blood RNA - plasmacytoid DC [nTPM]":"89.3","Blood RNA - T-reg [nTPM]":"113.8","Blood RNA - total PBMC [nTPM]":"116.1","Brain RNA - amygdala [nTPM]":"68.0","Brain RNA - basal ganglia [nTPM]":"72.2","Brain RNA - cerebellum [nTPM]":"80.6","Brain RNA - cerebral cortex [nTPM]":"84.3","Brain RNA - hippocampal formation [nTPM]":"69.9","Brain RNA - hypothalamus [nTPM]":"76.9","Brain RNA - medulla oblongata [nTPM]":"74.8","Brain RNA - midbrain [nTPM]":"71.4","Brain RNA - pons [nTPM]":"73.8","Brain RNA - spinal cord [nTPM]":"73.9","Brain RNA - thalamus [nTPM]":"74.9","Brain RNA - white matter [nTPM]":"78.9","Single Cell Type RNA - Adipocytes [nTPM]":"48.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.4","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"57.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"199.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.5","Single Cell Type RNA - Bipolar cells [nTPM]":"31.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"405.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"101.5","Single Cell Type RNA - Club cells [nTPM]":"97.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"107.1","Single Cell Type RNA - dendritic cells [nTPM]":"48.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"176.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"354.1","Single Cell Type RNA - Ductal cells [nTPM]":"134.3","Single Cell Type RNA - Early spermatids [nTPM]":"220.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.2","Single Cell Type RNA - Endothelial cells [nTPM]":"54.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"48.6","Single Cell Type RNA - Erythroid cells [nTPM]":"77.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"149.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"142.2","Single Cell Type RNA - Fibroblasts [nTPM]":"62.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.5","Single Cell Type RNA - granulocytes [nTPM]":"66.6","Single Cell Type RNA - Granulosa cells [nTPM]":"39.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.8","Single Cell Type RNA - Hepatocytes [nTPM]":"226.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"177.4","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.1","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"88.7","Single Cell Type RNA - Langerhans cells [nTPM]":"67.9","Single Cell Type RNA - Late spermatids [nTPM]":"30.5","Single Cell Type RNA - Leydig cells [nTPM]":"57.8","Single Cell Type RNA - Macrophages [nTPM]":"78.4","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"123.1","Single Cell Type RNA - Muller glia cells [nTPM]":"78.3","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"111.5","Single Cell Type RNA - Paneth cells [nTPM]":"218.3","Single Cell Type RNA - Peritubular cells [nTPM]":"67.7","Single Cell Type RNA - Plasma cells [nTPM]":"62.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"300.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"449.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"79.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"191.6","Single Cell Type RNA - Spermatocytes [nTPM]":"148.9","Single Cell Type RNA - Spermatogonia [nTPM]":"71.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"121.8","Single Cell Type RNA - T-cells [nTPM]":"46.8","Single Cell Type RNA - Theca cells [nTPM]":"69.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"162.0","Single Cell Type RNA - Urothelial cells [nTPM]":"110.9"},{"Gene":"SDHC","Gene synonym":["CYB560","cybL","PGL3"],"Ensembl":"ENSG00000143252","Gene description":"Succinate dehydrogenase complex subunit C","Uniprot":["Q99643"],"Chromosome":"1","Position":"161314381-161363206","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"776.7","Proximal tubular cells":"916.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"128.9","Tissue RNA - adrenal gland [nTPM]":"143.7","Tissue RNA - amygdala [nTPM]":"73.7","Tissue RNA - appendix [nTPM]":"64.1","Tissue RNA - basal ganglia [nTPM]":"79.7","Tissue RNA - bone marrow [nTPM]":"60.5","Tissue RNA - breast [nTPM]":"100.3","Tissue RNA - cerebellum [nTPM]":"84.5","Tissue RNA - cerebral cortex [nTPM]":"85.1","Tissue RNA - cervix [nTPM]":"78.7","Tissue RNA - choroid plexus [nTPM]":"92.9","Tissue RNA - colon [nTPM]":"118.9","Tissue RNA - duodenum [nTPM]":"127.8","Tissue RNA - endometrium 1 [nTPM]":"70.9","Tissue RNA - epididymis [nTPM]":"76.0","Tissue RNA - esophagus [nTPM]":"109.7","Tissue RNA - fallopian tube [nTPM]":"98.6","Tissue RNA - gallbladder [nTPM]":"63.3","Tissue RNA - heart muscle [nTPM]":"154.1","Tissue RNA - hippocampal formation [nTPM]":"68.4","Tissue RNA - hypothalamus [nTPM]":"83.4","Tissue RNA - kidney [nTPM]":"285.7","Tissue RNA - liver [nTPM]":"319.4","Tissue RNA - lung [nTPM]":"65.5","Tissue RNA - lymph node [nTPM]":"74.7","Tissue RNA - medulla oblongata [nTPM]":"78.8","Tissue RNA - midbrain [nTPM]":"79.1","Tissue RNA - ovary [nTPM]":"69.2","Tissue RNA - pancreas [nTPM]":"62.5","Tissue RNA - parathyroid gland [nTPM]":"173.6","Tissue RNA - pituitary gland [nTPM]":"52.4","Tissue RNA - placenta [nTPM]":"73.1","Tissue RNA - pons [nTPM]":"76.7","Tissue RNA - prostate [nTPM]":"77.3","Tissue RNA - rectum [nTPM]":"132.2","Tissue RNA - retina [nTPM]":"84.3","Tissue RNA - salivary gland [nTPM]":"74.8","Tissue RNA - seminal vesicle [nTPM]":"84.7","Tissue RNA - skeletal muscle [nTPM]":"277.4","Tissue RNA - skin 1 [nTPM]":"69.8","Tissue RNA - small intestine [nTPM]":"101.4","Tissue RNA - smooth muscle [nTPM]":"101.4","Tissue RNA - spinal cord [nTPM]":"85.1","Tissue RNA - spleen [nTPM]":"62.8","Tissue RNA - stomach 1 [nTPM]":"89.9","Tissue RNA - testis [nTPM]":"52.7","Tissue RNA - thalamus [nTPM]":"84.8","Tissue RNA - thymus [nTPM]":"93.1","Tissue RNA - thyroid gland [nTPM]":"89.5","Tissue RNA - tongue [nTPM]":"288.4","Tissue RNA - tonsil [nTPM]":"105.1","Tissue RNA - urinary bladder [nTPM]":"88.4","Tissue RNA - vagina [nTPM]":"61.3","Tissue RNA - white matter [nTPM]":"85.6","Cell RNA - A-431 [nTPM]":"161.1","Cell RNA - A549 [nTPM]":"129.7","Cell RNA - AF22 [nTPM]":"157.5","Cell RNA - AN3-CA [nTPM]":"147.7","Cell RNA - ASC diff [nTPM]":"248.3","Cell RNA - ASC TERT1 [nTPM]":"213.3","Cell RNA - BEWO [nTPM]":"196.3","Cell RNA - BJ [nTPM]":"150.9","Cell RNA - BJ hTERT+ [nTPM]":"190.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"180.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"137.3","Cell RNA - CACO-2 [nTPM]":"185.4","Cell RNA - CAPAN-2 [nTPM]":"208.7","Cell RNA - Daudi [nTPM]":"53.7","Cell RNA - EFO-21 [nTPM]":"190.6","Cell RNA - fHDF\/TERT166 [nTPM]":"214.8","Cell RNA - GAMG [nTPM]":"121.6","Cell RNA - HaCaT [nTPM]":"178.5","Cell RNA - HAP1 [nTPM]":"244.3","Cell RNA - HBEC3-KT [nTPM]":"214.2","Cell RNA - HBF TERT88 [nTPM]":"193.2","Cell RNA - HDLM-2 [nTPM]":"185.6","Cell RNA - HEK 293 [nTPM]":"205.6","Cell RNA - HEL [nTPM]":"110.2","Cell RNA - HeLa [nTPM]":"106.6","Cell RNA - Hep G2 [nTPM]":"196.7","Cell RNA - HHSteC [nTPM]":"126.9","Cell RNA - HL-60 [nTPM]":"193.8","Cell RNA - HMC-1 [nTPM]":"109.1","Cell RNA - HSkMC [nTPM]":"211.5","Cell RNA - hTCEpi [nTPM]":"181.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"174.3","Cell RNA - hTERT-HME1 [nTPM]":"119.4","Cell RNA - hTERT-RPE1 [nTPM]":"167.9","Cell RNA - HUVEC TERT2 [nTPM]":"177.5","Cell RNA - JURKAT [nTPM]":"164.0","Cell RNA - K-562 [nTPM]":"178.9","Cell RNA - Karpas-707 [nTPM]":"43.8","Cell RNA - LHCN-M2 [nTPM]":"266.3","Cell RNA - MCF7 [nTPM]":"167.0","Cell RNA - MOLT-4 [nTPM]":"152.4","Cell RNA - NB-4 [nTPM]":"112.5","Cell RNA - NTERA-2 [nTPM]":"145.4","Cell RNA - OE19 [nTPM]":"376.3","Cell RNA - PC-3 [nTPM]":"123.7","Cell RNA - REH [nTPM]":"131.6","Cell RNA - RH-30 [nTPM]":"151.0","Cell RNA - RPMI-8226 [nTPM]":"217.1","Cell RNA - RPTEC TERT1 [nTPM]":"330.3","Cell RNA - RT4 [nTPM]":"167.8","Cell RNA - SCLC-21H [nTPM]":"118.3","Cell RNA - SH-SY5Y [nTPM]":"180.7","Cell RNA - SiHa [nTPM]":"211.0","Cell RNA - SK-BR-3 [nTPM]":"385.1","Cell RNA - SK-MEL-30 [nTPM]":"225.4","Cell RNA - SuSa [nTPM]":"207.9","Cell RNA - T-47d [nTPM]":"342.1","Cell RNA - THP-1 [nTPM]":"259.3","Cell RNA - TIME [nTPM]":"133.5","Cell RNA - U-138 MG [nTPM]":"103.7","Cell RNA - U-2 OS [nTPM]":"125.1","Cell RNA - U-2197 [nTPM]":"127.9","Cell RNA - U-251 MG [nTPM]":"147.3","Cell RNA - U-266\/70 [nTPM]":"173.3","Cell RNA - U-266\/84 [nTPM]":"287.8","Cell RNA - U-698 [nTPM]":"269.4","Cell RNA - U-87 MG [nTPM]":"140.3","Cell RNA - U-937 [nTPM]":"139.2","Cell RNA - WM-115 [nTPM]":"193.6","Blood RNA - basophil [nTPM]":"88.6","Blood RNA - classical monocyte [nTPM]":"111.0","Blood RNA - eosinophil [nTPM]":"65.7","Blood RNA - gdT-cell [nTPM]":"76.6","Blood RNA - intermediate monocyte [nTPM]":"99.6","Blood RNA - MAIT T-cell [nTPM]":"79.6","Blood RNA - memory B-cell [nTPM]":"68.6","Blood RNA - memory CD4 T-cell [nTPM]":"66.2","Blood RNA - memory CD8 T-cell [nTPM]":"75.4","Blood RNA - myeloid DC [nTPM]":"136.1","Blood RNA - naive B-cell [nTPM]":"65.7","Blood RNA - naive CD4 T-cell [nTPM]":"71.2","Blood RNA - naive CD8 T-cell [nTPM]":"71.0","Blood RNA - neutrophil [nTPM]":"52.0","Blood RNA - NK-cell [nTPM]":"66.9","Blood RNA - non-classical monocyte [nTPM]":"87.5","Blood RNA - plasmacytoid DC [nTPM]":"100.6","Blood RNA - T-reg [nTPM]":"78.3","Blood RNA - total PBMC [nTPM]":"130.0","Brain RNA - amygdala [nTPM]":"73.7","Brain RNA - basal ganglia [nTPM]":"79.7","Brain RNA - cerebellum [nTPM]":"84.5","Brain RNA - cerebral cortex [nTPM]":"85.1","Brain RNA - hippocampal formation [nTPM]":"68.4","Brain RNA - hypothalamus [nTPM]":"83.4","Brain RNA - medulla oblongata [nTPM]":"78.8","Brain RNA - midbrain [nTPM]":"79.1","Brain RNA - pons [nTPM]":"76.7","Brain RNA - spinal cord [nTPM]":"85.1","Brain RNA - thalamus [nTPM]":"84.8","Brain RNA - white matter [nTPM]":"85.6","Single Cell Type RNA - Adipocytes [nTPM]":"50.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.4","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"70.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"61.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"151.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"342.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"59.7","Single Cell Type RNA - Bipolar cells [nTPM]":"74.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"94.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"131.5","Single Cell Type RNA - Club cells [nTPM]":"163.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"150.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"248.0","Single Cell Type RNA - dendritic cells [nTPM]":"65.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"95.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"776.7","Single Cell Type RNA - Ductal cells [nTPM]":"218.4","Single Cell Type RNA - Early spermatids [nTPM]":"18.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"87.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.8","Single Cell Type RNA - Endothelial cells [nTPM]":"80.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.8","Single Cell Type RNA - Erythroid cells [nTPM]":"81.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"145.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"248.5","Single Cell Type RNA - Fibroblasts [nTPM]":"79.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.6","Single Cell Type RNA - granulocytes [nTPM]":"58.3","Single Cell Type RNA - Granulosa cells [nTPM]":"66.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"83.2","Single Cell Type RNA - Hepatocytes [nTPM]":"249.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"237.3","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.4","Single Cell Type RNA - Ionocytes [nTPM]":"215.7","Single Cell Type RNA - Kupffer cells [nTPM]":"100.6","Single Cell Type RNA - Langerhans cells [nTPM]":"74.4","Single Cell Type RNA - Late spermatids [nTPM]":"34.7","Single Cell Type RNA - Leydig cells [nTPM]":"102.9","Single Cell Type RNA - Macrophages [nTPM]":"94.6","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"176.1","Single Cell Type RNA - Muller glia cells [nTPM]":"107.8","Single Cell Type RNA - NK-cells [nTPM]":"107.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"142.7","Single Cell Type RNA - Paneth cells [nTPM]":"89.5","Single Cell Type RNA - Peritubular cells [nTPM]":"109.1","Single Cell Type RNA - Plasma cells [nTPM]":"71.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"916.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"177.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.4","Single Cell Type RNA - Spermatocytes [nTPM]":"115.3","Single Cell Type RNA - Spermatogonia [nTPM]":"114.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"111.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"76.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"307.6","Single Cell Type RNA - T-cells [nTPM]":"72.0","Single Cell Type RNA - Theca cells [nTPM]":"215.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.2","Single Cell Type RNA - Urothelial cells [nTPM]":"155.0"},{"Gene":"SDHD","Gene synonym":["cybS","PGL","PGL1"],"Ensembl":"ENSG00000204370","Gene description":"Succinate dehydrogenase complex subunit D","Uniprot":["O14521"],"Chromosome":"11","Position":"112086824-112120016","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"530.2","Proximal tubular cells":"449.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045727":"AB_10963114"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.99e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"117.5","Tissue RNA - adrenal gland [nTPM]":"95.7","Tissue RNA - amygdala [nTPM]":"60.0","Tissue RNA - appendix [nTPM]":"84.5","Tissue RNA - basal ganglia [nTPM]":"63.1","Tissue RNA - bone marrow [nTPM]":"72.9","Tissue RNA - breast [nTPM]":"102.6","Tissue RNA - cerebellum [nTPM]":"68.6","Tissue RNA - cerebral cortex [nTPM]":"76.3","Tissue RNA - cervix [nTPM]":"92.5","Tissue RNA - choroid plexus [nTPM]":"65.1","Tissue RNA - colon [nTPM]":"185.2","Tissue RNA - duodenum [nTPM]":"208.1","Tissue RNA - endometrium 1 [nTPM]":"88.2","Tissue RNA - epididymis [nTPM]":"96.7","Tissue RNA - esophagus [nTPM]":"126.7","Tissue RNA - fallopian tube [nTPM]":"92.6","Tissue RNA - gallbladder [nTPM]":"85.6","Tissue RNA - heart muscle [nTPM]":"254.7","Tissue RNA - hippocampal formation [nTPM]":"60.1","Tissue RNA - hypothalamus [nTPM]":"65.4","Tissue RNA - kidney [nTPM]":"319.9","Tissue RNA - liver [nTPM]":"391.8","Tissue RNA - lung [nTPM]":"79.3","Tissue RNA - lymph node [nTPM]":"131.7","Tissue RNA - medulla oblongata [nTPM]":"63.4","Tissue RNA - midbrain [nTPM]":"62.5","Tissue RNA - ovary [nTPM]":"91.6","Tissue RNA - pancreas [nTPM]":"77.8","Tissue RNA - parathyroid gland [nTPM]":"152.4","Tissue RNA - pituitary gland [nTPM]":"37.0","Tissue RNA - placenta [nTPM]":"95.0","Tissue RNA - pons [nTPM]":"63.2","Tissue RNA - prostate [nTPM]":"87.9","Tissue RNA - rectum [nTPM]":"190.8","Tissue RNA - retina [nTPM]":"37.4","Tissue RNA - salivary gland [nTPM]":"112.6","Tissue RNA - seminal vesicle [nTPM]":"100.9","Tissue RNA - skeletal muscle [nTPM]":"354.7","Tissue RNA - skin 1 [nTPM]":"64.3","Tissue RNA - small intestine [nTPM]":"175.6","Tissue RNA - smooth muscle [nTPM]":"98.1","Tissue RNA - spinal cord [nTPM]":"64.7","Tissue RNA - spleen [nTPM]":"85.1","Tissue RNA - stomach 1 [nTPM]":"101.1","Tissue RNA - testis [nTPM]":"34.1","Tissue RNA - thalamus [nTPM]":"63.7","Tissue RNA - thymus [nTPM]":"102.5","Tissue RNA - thyroid gland [nTPM]":"136.8","Tissue RNA - tongue [nTPM]":"449.6","Tissue RNA - tonsil [nTPM]":"124.8","Tissue RNA - urinary bladder [nTPM]":"117.9","Tissue RNA - vagina [nTPM]":"76.4","Tissue RNA - white matter [nTPM]":"68.2","Cell RNA - A-431 [nTPM]":"84.0","Cell RNA - A549 [nTPM]":"67.3","Cell RNA - AF22 [nTPM]":"58.1","Cell RNA - AN3-CA [nTPM]":"89.4","Cell RNA - ASC diff [nTPM]":"212.0","Cell RNA - ASC TERT1 [nTPM]":"170.7","Cell RNA - BEWO [nTPM]":"97.3","Cell RNA - BJ [nTPM]":"97.5","Cell RNA - BJ hTERT+ [nTPM]":"147.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"106.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"132.2","Cell RNA - CACO-2 [nTPM]":"244.8","Cell RNA - CAPAN-2 [nTPM]":"222.1","Cell RNA - Daudi [nTPM]":"155.5","Cell RNA - EFO-21 [nTPM]":"288.4","Cell RNA - fHDF\/TERT166 [nTPM]":"131.0","Cell RNA - GAMG [nTPM]":"156.1","Cell RNA - HaCaT [nTPM]":"203.5","Cell RNA - HAP1 [nTPM]":"175.4","Cell RNA - HBEC3-KT [nTPM]":"139.8","Cell RNA - HBF TERT88 [nTPM]":"129.8","Cell RNA - HDLM-2 [nTPM]":"129.9","Cell RNA - HEK 293 [nTPM]":"92.4","Cell RNA - HEL [nTPM]":"142.8","Cell RNA - HeLa [nTPM]":"51.9","Cell RNA - Hep G2 [nTPM]":"140.1","Cell RNA - HHSteC [nTPM]":"165.6","Cell RNA - HL-60 [nTPM]":"222.4","Cell RNA - HMC-1 [nTPM]":"107.5","Cell RNA - HSkMC [nTPM]":"189.6","Cell RNA - hTCEpi [nTPM]":"160.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"110.5","Cell RNA - hTERT-HME1 [nTPM]":"189.1","Cell RNA - hTERT-RPE1 [nTPM]":"124.6","Cell RNA - HUVEC TERT2 [nTPM]":"153.0","Cell RNA - JURKAT [nTPM]":"109.6","Cell RNA - K-562 [nTPM]":"156.0","Cell RNA - Karpas-707 [nTPM]":"208.7","Cell RNA - LHCN-M2 [nTPM]":"135.0","Cell RNA - MCF7 [nTPM]":"95.2","Cell RNA - MOLT-4 [nTPM]":"143.9","Cell RNA - NB-4 [nTPM]":"215.0","Cell RNA - NTERA-2 [nTPM]":"77.4","Cell RNA - OE19 [nTPM]":"333.8","Cell RNA - PC-3 [nTPM]":"211.6","Cell RNA - REH [nTPM]":"126.2","Cell RNA - RH-30 [nTPM]":"145.8","Cell RNA - RPMI-8226 [nTPM]":"294.4","Cell RNA - RPTEC TERT1 [nTPM]":"221.6","Cell RNA - RT4 [nTPM]":"175.2","Cell RNA - SCLC-21H [nTPM]":"83.5","Cell RNA - SH-SY5Y [nTPM]":"55.8","Cell RNA - SiHa [nTPM]":"135.3","Cell RNA - SK-BR-3 [nTPM]":"194.8","Cell RNA - SK-MEL-30 [nTPM]":"107.0","Cell RNA - SuSa [nTPM]":"81.8","Cell RNA - T-47d [nTPM]":"198.9","Cell RNA - THP-1 [nTPM]":"164.2","Cell RNA - TIME [nTPM]":"108.0","Cell RNA - U-138 MG [nTPM]":"103.8","Cell RNA - U-2 OS [nTPM]":"132.3","Cell RNA - U-2197 [nTPM]":"114.7","Cell RNA - U-251 MG [nTPM]":"95.0","Cell RNA - U-266\/70 [nTPM]":"59.1","Cell RNA - U-266\/84 [nTPM]":"73.2","Cell RNA - U-698 [nTPM]":"270.7","Cell RNA - U-87 MG [nTPM]":"58.8","Cell RNA - U-937 [nTPM]":"297.0","Cell RNA - WM-115 [nTPM]":"100.5","Blood RNA - basophil [nTPM]":"233.7","Blood RNA - classical monocyte [nTPM]":"293.3","Blood RNA - eosinophil [nTPM]":"208.8","Blood RNA - gdT-cell [nTPM]":"158.4","Blood RNA - intermediate monocyte [nTPM]":"390.1","Blood RNA - MAIT T-cell [nTPM]":"173.1","Blood RNA - memory B-cell [nTPM]":"235.2","Blood RNA - memory CD4 T-cell [nTPM]":"170.8","Blood RNA - memory CD8 T-cell [nTPM]":"168.8","Blood RNA - myeloid DC [nTPM]":"308.7","Blood RNA - naive B-cell [nTPM]":"198.1","Blood RNA - naive CD4 T-cell [nTPM]":"204.3","Blood RNA - naive CD8 T-cell [nTPM]":"191.8","Blood RNA - neutrophil [nTPM]":"257.5","Blood RNA - NK-cell [nTPM]":"207.9","Blood RNA - non-classical monocyte [nTPM]":"322.9","Blood RNA - plasmacytoid DC [nTPM]":"151.7","Blood RNA - T-reg [nTPM]":"189.9","Blood RNA - total PBMC [nTPM]":"348.9","Brain RNA - amygdala [nTPM]":"60.0","Brain RNA - basal ganglia [nTPM]":"63.1","Brain RNA - cerebellum [nTPM]":"68.6","Brain RNA - cerebral cortex [nTPM]":"76.3","Brain RNA - hippocampal formation [nTPM]":"60.1","Brain RNA - hypothalamus [nTPM]":"65.4","Brain RNA - medulla oblongata [nTPM]":"63.4","Brain RNA - midbrain [nTPM]":"62.5","Brain RNA - pons [nTPM]":"63.2","Brain RNA - spinal cord [nTPM]":"64.7","Brain RNA - thalamus [nTPM]":"63.7","Brain RNA - white matter [nTPM]":"68.2","Single Cell Type RNA - Adipocytes [nTPM]":"104.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"78.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"81.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"102.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"262.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"78.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"216.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"120.1","Single Cell Type RNA - Club cells [nTPM]":"108.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"90.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"154.3","Single Cell Type RNA - dendritic cells [nTPM]":"55.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"203.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"530.2","Single Cell Type RNA - Ductal cells [nTPM]":"82.9","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.6","Single Cell Type RNA - Endothelial cells [nTPM]":"76.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.4","Single Cell Type RNA - Erythroid cells [nTPM]":"70.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"124.1","Single Cell Type RNA - Fibroblasts [nTPM]":"104.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"75.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.2","Single Cell Type RNA - granulocytes [nTPM]":"65.9","Single Cell Type RNA - Granulosa cells [nTPM]":"32.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"76.8","Single Cell Type RNA - Hepatocytes [nTPM]":"169.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"162.9","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"129.1","Single Cell Type RNA - Ionocytes [nTPM]":"154.6","Single Cell Type RNA - Kupffer cells [nTPM]":"97.1","Single Cell Type RNA - Langerhans cells [nTPM]":"74.4","Single Cell Type RNA - Late spermatids [nTPM]":"37.0","Single Cell Type RNA - Leydig cells [nTPM]":"104.1","Single Cell Type RNA - Macrophages [nTPM]":"94.2","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"118.6","Single Cell Type RNA - Muller glia cells [nTPM]":"52.9","Single Cell Type RNA - NK-cells [nTPM]":"75.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.1","Single Cell Type RNA - Paneth cells [nTPM]":"134.2","Single Cell Type RNA - Peritubular cells [nTPM]":"99.6","Single Cell Type RNA - Plasma cells [nTPM]":"80.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"253.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"449.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"60.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.9","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"78.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"110.7","Single Cell Type RNA - Spermatocytes [nTPM]":"70.4","Single Cell Type RNA - Spermatogonia [nTPM]":"55.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"127.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"179.0","Single Cell Type RNA - T-cells [nTPM]":"71.4","Single Cell Type RNA - Theca cells [nTPM]":"86.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"176.0","Single Cell Type RNA - Urothelial cells [nTPM]":"98.6"},{"Gene":"TFG","Gene synonym":["FLJ36137","SPG57","TF6"],"Ensembl":"ENSG00000114354","Gene description":"Trafficking from ER to golgi regulator","Uniprot":["Q92734"],"Chromosome":"3","Position":"100709295-100748964","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019473","HPA052206"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019473":"AB_1857936","HPA052206":"AB_2681760"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"62.2","Tissue RNA - adrenal gland [nTPM]":"73.0","Tissue RNA - amygdala [nTPM]":"40.7","Tissue RNA - appendix [nTPM]":"37.2","Tissue RNA - basal ganglia [nTPM]":"40.4","Tissue RNA - bone marrow [nTPM]":"37.4","Tissue RNA - breast [nTPM]":"52.4","Tissue RNA - cerebellum [nTPM]":"43.5","Tissue RNA - cerebral cortex [nTPM]":"46.4","Tissue RNA - cervix [nTPM]":"53.9","Tissue RNA - choroid plexus [nTPM]":"46.7","Tissue RNA - colon [nTPM]":"63.8","Tissue RNA - duodenum [nTPM]":"89.8","Tissue RNA - endometrium 1 [nTPM]":"52.0","Tissue RNA - epididymis [nTPM]":"78.5","Tissue RNA - esophagus [nTPM]":"85.7","Tissue RNA - fallopian tube [nTPM]":"51.2","Tissue RNA - gallbladder [nTPM]":"56.4","Tissue RNA - heart muscle [nTPM]":"82.6","Tissue RNA - hippocampal formation [nTPM]":"41.3","Tissue RNA - hypothalamus [nTPM]":"45.4","Tissue RNA - kidney [nTPM]":"71.9","Tissue RNA - liver [nTPM]":"113.9","Tissue RNA - lung [nTPM]":"55.6","Tissue RNA - lymph node [nTPM]":"29.4","Tissue RNA - medulla oblongata [nTPM]":"44.2","Tissue RNA - midbrain [nTPM]":"43.2","Tissue RNA - ovary [nTPM]":"48.2","Tissue RNA - pancreas [nTPM]":"66.7","Tissue RNA - parathyroid gland [nTPM]":"89.0","Tissue RNA - pituitary gland [nTPM]":"64.1","Tissue RNA - placenta [nTPM]":"79.2","Tissue RNA - pons [nTPM]":"44.4","Tissue RNA - prostate [nTPM]":"47.9","Tissue RNA - rectum [nTPM]":"69.6","Tissue RNA - retina [nTPM]":"40.9","Tissue RNA - salivary gland [nTPM]":"60.6","Tissue RNA - seminal vesicle [nTPM]":"61.3","Tissue RNA - skeletal muscle [nTPM]":"75.5","Tissue RNA - skin 1 [nTPM]":"58.9","Tissue RNA - small intestine [nTPM]":"76.6","Tissue RNA - smooth muscle [nTPM]":"66.5","Tissue RNA - spinal cord [nTPM]":"43.2","Tissue RNA - spleen [nTPM]":"42.6","Tissue RNA - stomach 1 [nTPM]":"54.4","Tissue RNA - testis [nTPM]":"47.7","Tissue RNA - thalamus [nTPM]":"42.3","Tissue RNA - thymus [nTPM]":"40.6","Tissue RNA - thyroid gland [nTPM]":"64.1","Tissue RNA - tongue [nTPM]":"58.2","Tissue RNA - tonsil [nTPM]":"54.9","Tissue RNA - urinary bladder [nTPM]":"61.6","Tissue RNA - vagina [nTPM]":"57.3","Tissue RNA - white matter [nTPM]":"44.4","Cell RNA - A-431 [nTPM]":"203.8","Cell RNA - A549 [nTPM]":"107.5","Cell RNA - AF22 [nTPM]":"126.7","Cell RNA - AN3-CA [nTPM]":"79.0","Cell RNA - ASC diff [nTPM]":"160.1","Cell RNA - ASC TERT1 [nTPM]":"176.4","Cell RNA - BEWO [nTPM]":"163.9","Cell RNA - BJ [nTPM]":"141.1","Cell RNA - BJ hTERT+ [nTPM]":"190.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"182.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"213.0","Cell RNA - CACO-2 [nTPM]":"136.0","Cell RNA - CAPAN-2 [nTPM]":"96.1","Cell RNA - Daudi [nTPM]":"24.7","Cell RNA - EFO-21 [nTPM]":"103.3","Cell RNA - fHDF\/TERT166 [nTPM]":"180.4","Cell RNA - GAMG [nTPM]":"141.3","Cell RNA - HaCaT [nTPM]":"143.1","Cell RNA - HAP1 [nTPM]":"143.4","Cell RNA - HBEC3-KT [nTPM]":"161.5","Cell RNA - HBF TERT88 [nTPM]":"216.2","Cell RNA - HDLM-2 [nTPM]":"123.8","Cell RNA - HEK 293 [nTPM]":"87.4","Cell RNA - HEL [nTPM]":"99.7","Cell RNA - HeLa [nTPM]":"69.3","Cell RNA - Hep G2 [nTPM]":"130.0","Cell RNA - HHSteC [nTPM]":"183.3","Cell RNA - HL-60 [nTPM]":"70.2","Cell RNA - HMC-1 [nTPM]":"51.8","Cell RNA - HSkMC [nTPM]":"149.3","Cell RNA - hTCEpi [nTPM]":"216.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.4","Cell RNA - hTERT-HME1 [nTPM]":"190.8","Cell RNA - hTERT-RPE1 [nTPM]":"165.1","Cell RNA - HUVEC TERT2 [nTPM]":"165.5","Cell RNA - JURKAT [nTPM]":"44.5","Cell RNA - K-562 [nTPM]":"73.1","Cell RNA - Karpas-707 [nTPM]":"63.5","Cell RNA - LHCN-M2 [nTPM]":"191.9","Cell RNA - MCF7 [nTPM]":"143.9","Cell RNA - MOLT-4 [nTPM]":"63.3","Cell RNA - NB-4 [nTPM]":"56.7","Cell RNA - NTERA-2 [nTPM]":"122.5","Cell RNA - OE19 [nTPM]":"193.8","Cell RNA - PC-3 [nTPM]":"169.3","Cell RNA - REH [nTPM]":"55.5","Cell RNA - RH-30 [nTPM]":"77.8","Cell RNA - RPMI-8226 [nTPM]":"89.0","Cell RNA - RPTEC TERT1 [nTPM]":"226.5","Cell RNA - RT4 [nTPM]":"125.9","Cell RNA - SCLC-21H [nTPM]":"96.4","Cell RNA - SH-SY5Y [nTPM]":"93.1","Cell RNA - SiHa [nTPM]":"95.0","Cell RNA - SK-BR-3 [nTPM]":"118.2","Cell RNA - SK-MEL-30 [nTPM]":"175.8","Cell RNA - SuSa [nTPM]":"103.4","Cell RNA - T-47d [nTPM]":"141.7","Cell RNA - THP-1 [nTPM]":"103.1","Cell RNA - TIME [nTPM]":"113.1","Cell RNA - U-138 MG [nTPM]":"103.0","Cell RNA - U-2 OS [nTPM]":"130.8","Cell RNA - U-2197 [nTPM]":"48.4","Cell RNA - U-251 MG [nTPM]":"104.4","Cell RNA - U-266\/70 [nTPM]":"56.2","Cell RNA - U-266\/84 [nTPM]":"65.8","Cell RNA - U-698 [nTPM]":"92.1","Cell RNA - U-87 MG [nTPM]":"171.2","Cell RNA - U-937 [nTPM]":"79.7","Cell RNA - WM-115 [nTPM]":"130.7","Blood RNA - basophil [nTPM]":"84.3","Blood RNA - classical monocyte [nTPM]":"43.6","Blood RNA - eosinophil [nTPM]":"42.8","Blood RNA - gdT-cell [nTPM]":"30.8","Blood RNA - intermediate monocyte [nTPM]":"45.2","Blood RNA - MAIT T-cell [nTPM]":"37.4","Blood RNA - memory B-cell [nTPM]":"37.4","Blood RNA - memory CD4 T-cell [nTPM]":"31.6","Blood RNA - memory CD8 T-cell [nTPM]":"34.5","Blood RNA - myeloid DC [nTPM]":"43.1","Blood RNA - naive B-cell [nTPM]":"35.9","Blood RNA - naive CD4 T-cell [nTPM]":"29.4","Blood RNA - naive CD8 T-cell [nTPM]":"29.7","Blood RNA - neutrophil [nTPM]":"26.1","Blood RNA - NK-cell [nTPM]":"43.1","Blood RNA - non-classical monocyte [nTPM]":"44.8","Blood RNA - plasmacytoid DC [nTPM]":"29.3","Blood RNA - T-reg [nTPM]":"41.0","Blood RNA - total PBMC [nTPM]":"37.0","Brain RNA - amygdala [nTPM]":"40.7","Brain RNA - basal ganglia [nTPM]":"40.4","Brain RNA - cerebellum [nTPM]":"43.5","Brain RNA - cerebral cortex [nTPM]":"46.4","Brain RNA - hippocampal formation [nTPM]":"41.3","Brain RNA - hypothalamus [nTPM]":"45.4","Brain RNA - medulla oblongata [nTPM]":"44.2","Brain RNA - midbrain [nTPM]":"43.2","Brain RNA - pons [nTPM]":"44.4","Brain RNA - spinal cord [nTPM]":"43.2","Brain RNA - thalamus [nTPM]":"42.3","Brain RNA - white matter [nTPM]":"44.4","Single Cell Type RNA - Adipocytes [nTPM]":"67.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.9","Single Cell Type RNA - Astrocytes [nTPM]":"46.4","Single Cell Type RNA - B-cells [nTPM]":"43.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"136.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"183.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"69.4","Single Cell Type RNA - Bipolar cells [nTPM]":"46.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"83.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"93.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"211.6","Single Cell Type RNA - dendritic cells [nTPM]":"43.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"111.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"137.0","Single Cell Type RNA - Ductal cells [nTPM]":"190.3","Single Cell Type RNA - Early spermatids [nTPM]":"101.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"70.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.4","Single Cell Type RNA - Endothelial cells [nTPM]":"70.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.6","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"107.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"201.5","Single Cell Type RNA - Fibroblasts [nTPM]":"97.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"79.0","Single Cell Type RNA - granulocytes [nTPM]":"76.8","Single Cell Type RNA - Granulosa cells [nTPM]":"62.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"68.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.2","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"128.5","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"27.3","Single Cell Type RNA - Langerhans cells [nTPM]":"84.9","Single Cell Type RNA - Late spermatids [nTPM]":"45.5","Single Cell Type RNA - Leydig cells [nTPM]":"70.8","Single Cell Type RNA - Macrophages [nTPM]":"43.6","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"98.5","Single Cell Type RNA - Muller glia cells [nTPM]":"88.0","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"55.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"130.5","Single Cell Type RNA - Paneth cells [nTPM]":"91.0","Single Cell Type RNA - Peritubular cells [nTPM]":"74.1","Single Cell Type RNA - Plasma cells [nTPM]":"75.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"133.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"202.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"106.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"63.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"87.2","Single Cell Type RNA - Spermatocytes [nTPM]":"79.2","Single Cell Type RNA - Spermatogonia [nTPM]":"51.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"118.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"284.4","Single Cell Type RNA - T-cells [nTPM]":"43.2","Single Cell Type RNA - Theca cells [nTPM]":"90.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"97.2","Single Cell Type RNA - Urothelial cells [nTPM]":"123.0"},{"Gene":"TMEM127","Gene synonym":["FLJ20507","FLJ22257"],"Ensembl":"ENSG00000135956","Gene description":"Transmembrane protein 127","Uniprot":["O75204"],"Chromosome":"2","Position":"96248514-96265997","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"88.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.3","Tissue RNA - adrenal gland [nTPM]":"34.6","Tissue RNA - amygdala [nTPM]":"25.9","Tissue RNA - appendix [nTPM]":"28.5","Tissue RNA - basal ganglia [nTPM]":"24.6","Tissue RNA - bone marrow [nTPM]":"53.0","Tissue RNA - breast [nTPM]":"25.6","Tissue RNA - cerebellum [nTPM]":"20.1","Tissue RNA - cerebral cortex [nTPM]":"30.6","Tissue RNA - cervix [nTPM]":"30.7","Tissue RNA - choroid plexus [nTPM]":"15.7","Tissue RNA - colon [nTPM]":"34.4","Tissue RNA - duodenum [nTPM]":"32.6","Tissue RNA - endometrium 1 [nTPM]":"30.0","Tissue RNA - epididymis [nTPM]":"21.4","Tissue RNA - esophagus [nTPM]":"40.0","Tissue RNA - fallopian tube [nTPM]":"25.2","Tissue RNA - gallbladder [nTPM]":"32.3","Tissue RNA - heart muscle [nTPM]":"67.8","Tissue RNA - hippocampal formation [nTPM]":"26.7","Tissue RNA - hypothalamus [nTPM]":"23.6","Tissue RNA - kidney [nTPM]":"29.5","Tissue RNA - liver [nTPM]":"35.4","Tissue RNA - lung [nTPM]":"31.6","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"24.5","Tissue RNA - midbrain [nTPM]":"26.3","Tissue RNA - ovary [nTPM]":"31.9","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"73.1","Tissue RNA - pituitary gland [nTPM]":"29.4","Tissue RNA - placenta [nTPM]":"26.8","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"26.1","Tissue RNA - rectum [nTPM]":"30.5","Tissue RNA - retina [nTPM]":"27.6","Tissue RNA - salivary gland [nTPM]":"39.7","Tissue RNA - seminal vesicle [nTPM]":"42.4","Tissue RNA - skeletal muscle [nTPM]":"25.9","Tissue RNA - skin 1 [nTPM]":"33.0","Tissue RNA - small intestine [nTPM]":"34.7","Tissue RNA - smooth muscle [nTPM]":"35.1","Tissue RNA - spinal cord [nTPM]":"21.1","Tissue RNA - spleen [nTPM]":"34.7","Tissue RNA - stomach 1 [nTPM]":"27.8","Tissue RNA - testis [nTPM]":"10.2","Tissue RNA - thalamus [nTPM]":"29.7","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"26.2","Tissue RNA - tongue [nTPM]":"30.6","Tissue RNA - tonsil [nTPM]":"25.4","Tissue RNA - urinary bladder [nTPM]":"38.6","Tissue RNA - vagina [nTPM]":"27.8","Tissue RNA - white matter [nTPM]":"21.9","Cell RNA - A-431 [nTPM]":"28.8","Cell RNA - A549 [nTPM]":"38.0","Cell RNA - AF22 [nTPM]":"19.9","Cell RNA - AN3-CA [nTPM]":"30.7","Cell RNA - ASC diff [nTPM]":"86.0","Cell RNA - ASC TERT1 [nTPM]":"43.3","Cell RNA - BEWO [nTPM]":"36.7","Cell RNA - BJ [nTPM]":"36.9","Cell RNA - BJ hTERT+ [nTPM]":"65.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.2","Cell RNA - CACO-2 [nTPM]":"37.9","Cell RNA - CAPAN-2 [nTPM]":"40.0","Cell RNA - Daudi [nTPM]":"17.9","Cell RNA - EFO-21 [nTPM]":"52.8","Cell RNA - fHDF\/TERT166 [nTPM]":"73.3","Cell RNA - GAMG [nTPM]":"67.8","Cell RNA - HaCaT [nTPM]":"45.1","Cell RNA - HAP1 [nTPM]":"23.1","Cell RNA - HBEC3-KT [nTPM]":"34.2","Cell RNA - HBF TERT88 [nTPM]":"26.8","Cell RNA - HDLM-2 [nTPM]":"36.1","Cell RNA - HEK 293 [nTPM]":"17.8","Cell RNA - HEL [nTPM]":"31.2","Cell RNA - HeLa [nTPM]":"17.6","Cell RNA - Hep G2 [nTPM]":"37.5","Cell RNA - HHSteC [nTPM]":"55.4","Cell RNA - HL-60 [nTPM]":"26.7","Cell RNA - HMC-1 [nTPM]":"54.0","Cell RNA - HSkMC [nTPM]":"52.7","Cell RNA - hTCEpi [nTPM]":"48.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.0","Cell RNA - hTERT-HME1 [nTPM]":"35.3","Cell RNA - hTERT-RPE1 [nTPM]":"51.4","Cell RNA - HUVEC TERT2 [nTPM]":"44.5","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"19.5","Cell RNA - Karpas-707 [nTPM]":"37.6","Cell RNA - LHCN-M2 [nTPM]":"39.8","Cell RNA - MCF7 [nTPM]":"32.8","Cell RNA - MOLT-4 [nTPM]":"17.6","Cell RNA - NB-4 [nTPM]":"16.8","Cell RNA - NTERA-2 [nTPM]":"27.3","Cell RNA - OE19 [nTPM]":"33.9","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"16.4","Cell RNA - RH-30 [nTPM]":"25.0","Cell RNA - RPMI-8226 [nTPM]":"26.9","Cell RNA - RPTEC TERT1 [nTPM]":"42.9","Cell RNA - RT4 [nTPM]":"48.7","Cell RNA - SCLC-21H [nTPM]":"22.3","Cell RNA - SH-SY5Y [nTPM]":"23.4","Cell RNA - SiHa [nTPM]":"27.1","Cell RNA - SK-BR-3 [nTPM]":"63.8","Cell RNA - SK-MEL-30 [nTPM]":"31.3","Cell RNA - SuSa [nTPM]":"40.2","Cell RNA - T-47d [nTPM]":"23.6","Cell RNA - THP-1 [nTPM]":"28.2","Cell RNA - TIME [nTPM]":"52.5","Cell RNA - U-138 MG [nTPM]":"63.9","Cell RNA - U-2 OS [nTPM]":"36.2","Cell RNA - U-2197 [nTPM]":"55.9","Cell RNA - U-251 MG [nTPM]":"25.8","Cell RNA - U-266\/70 [nTPM]":"28.2","Cell RNA - U-266\/84 [nTPM]":"29.6","Cell RNA - U-698 [nTPM]":"14.1","Cell RNA - U-87 MG [nTPM]":"42.6","Cell RNA - U-937 [nTPM]":"30.9","Cell RNA - WM-115 [nTPM]":"34.7","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"8.2","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"6.6","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"4.3","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"14.3","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"5.3","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"25.9","Brain RNA - basal ganglia [nTPM]":"24.6","Brain RNA - cerebellum [nTPM]":"20.1","Brain RNA - cerebral cortex [nTPM]":"30.6","Brain RNA - hippocampal formation [nTPM]":"26.7","Brain RNA - hypothalamus [nTPM]":"23.6","Brain RNA - medulla oblongata [nTPM]":"24.5","Brain RNA - midbrain [nTPM]":"26.3","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"21.1","Brain RNA - thalamus [nTPM]":"29.7","Brain RNA - white matter [nTPM]":"21.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.3","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - dendritic cells [nTPM]":"19.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"88.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"29.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.1","Single Cell Type RNA - Endothelial cells [nTPM]":"23.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.1","Single Cell Type RNA - Fibroblasts [nTPM]":"16.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.8","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"35.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.7","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"59.8","Single Cell Type RNA - Langerhans cells [nTPM]":"33.2","Single Cell Type RNA - Late spermatids [nTPM]":"5.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"34.0","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"41.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.0","Single Cell Type RNA - Paneth cells [nTPM]":"35.1","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.4","Single Cell Type RNA - Spermatocytes [nTPM]":"9.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - T-cells [nTPM]":"14.3","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"34.1"},{"Gene":"TP53","Gene synonym":["LFS1","p53"],"Ensembl":"ENSG00000141510","Gene description":"Tumor protein p53","Uniprot":["P04637"],"Chromosome":"17","Position":"7661779-7687538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Host-virus interaction","Necrosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002973","CAB039238","CAB039239","HPA051244","HPA063532","CAB072876","CAB079965"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"CAB002973":"AB_2206626","CAB039238":null,"CAB039239":null,"CAB072876":"AB_2665731","CAB079965":null,"HPA051244":"AB_2681403","HPA063532":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.3","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"22.5","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"29.0","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"24.5","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"28.8","Tissue RNA - fallopian tube [nTPM]":"31.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"27.3","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"37.4","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"24.6","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"31.1","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"45.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"81.5","Cell RNA - A549 [nTPM]":"145.3","Cell RNA - AF22 [nTPM]":"81.1","Cell RNA - AN3-CA [nTPM]":"57.3","Cell RNA - ASC diff [nTPM]":"37.3","Cell RNA - ASC TERT1 [nTPM]":"43.9","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.2","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"40.6","Cell RNA - Daudi [nTPM]":"190.5","Cell RNA - EFO-21 [nTPM]":"126.9","Cell RNA - fHDF\/TERT166 [nTPM]":"58.7","Cell RNA - GAMG [nTPM]":"77.6","Cell RNA - HaCaT [nTPM]":"174.9","Cell RNA - HAP1 [nTPM]":"119.7","Cell RNA - HBEC3-KT [nTPM]":"80.4","Cell RNA - HBF TERT88 [nTPM]":"72.8","Cell RNA - HDLM-2 [nTPM]":"42.7","Cell RNA - HEK 293 [nTPM]":"76.5","Cell RNA - HEL [nTPM]":"77.6","Cell RNA - HeLa [nTPM]":"76.8","Cell RNA - Hep G2 [nTPM]":"70.9","Cell RNA - HHSteC [nTPM]":"111.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"37.0","Cell RNA - HSkMC [nTPM]":"55.7","Cell RNA - hTCEpi [nTPM]":"93.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.9","Cell RNA - hTERT-HME1 [nTPM]":"106.5","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"145.1","Cell RNA - MOLT-4 [nTPM]":"130.0","Cell RNA - NB-4 [nTPM]":"96.3","Cell RNA - NTERA-2 [nTPM]":"80.2","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"252.2","Cell RNA - RH-30 [nTPM]":"56.1","Cell RNA - RPMI-8226 [nTPM]":"66.2","Cell RNA - RPTEC TERT1 [nTPM]":"59.4","Cell RNA - RT4 [nTPM]":"87.3","Cell RNA - SCLC-21H [nTPM]":"46.0","Cell RNA - SH-SY5Y [nTPM]":"80.5","Cell RNA - SiHa [nTPM]":"94.1","Cell RNA - SK-BR-3 [nTPM]":"62.6","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"39.4","Cell RNA - T-47d [nTPM]":"109.2","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"100.7","Cell RNA - U-138 MG [nTPM]":"91.6","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"48.3","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"37.9","Cell RNA - U-698 [nTPM]":"82.5","Cell RNA - U-87 MG [nTPM]":"23.6","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"80.1","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"21.7","Blood RNA - MAIT T-cell [nTPM]":"15.9","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"30.3","Blood RNA - naive B-cell [nTPM]":"19.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"27.3","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"27.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"TPM3","Gene synonym":["NEM1","TRK"],"Ensembl":"ENSG00000143549","Gene description":"Tropomyosin 3","Uniprot":["P06753"],"Chromosome":"1","Position":"154155304-154194648","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Muscle protein"],"Disease involvement":["Cancer-related genes","Disease variant","Nemaline myopathy","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"skeletal muscle":"8905.8","tongue":"6106.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000261","HPA009066","HPA047089","HPA053624"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000261":"AB_1080339","HPA009066":"AB_1080342","HPA047089":"AB_2679928","HPA053624":"AB_2682210"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.73e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"140.7","Tissue RNA - adrenal gland [nTPM]":"103.2","Tissue RNA - amygdala [nTPM]":"95.0","Tissue RNA - appendix [nTPM]":"233.2","Tissue RNA - basal ganglia [nTPM]":"104.1","Tissue RNA - bone marrow [nTPM]":"590.1","Tissue RNA - breast [nTPM]":"97.1","Tissue RNA - cerebellum [nTPM]":"83.3","Tissue RNA - cerebral cortex [nTPM]":"116.2","Tissue RNA - cervix [nTPM]":"94.9","Tissue RNA - choroid plexus [nTPM]":"73.3","Tissue RNA - colon [nTPM]":"199.0","Tissue RNA - duodenum [nTPM]":"163.5","Tissue RNA - endometrium 1 [nTPM]":"69.6","Tissue RNA - epididymis [nTPM]":"73.4","Tissue RNA - esophagus [nTPM]":"287.4","Tissue RNA - fallopian tube [nTPM]":"100.6","Tissue RNA - gallbladder [nTPM]":"136.1","Tissue RNA - heart muscle [nTPM]":"318.5","Tissue RNA - hippocampal formation [nTPM]":"104.8","Tissue RNA - hypothalamus [nTPM]":"101.5","Tissue RNA - kidney [nTPM]":"81.5","Tissue RNA - liver [nTPM]":"114.4","Tissue RNA - lung [nTPM]":"178.7","Tissue RNA - lymph node [nTPM]":"287.3","Tissue RNA - medulla oblongata [nTPM]":"96.6","Tissue RNA - midbrain [nTPM]":"101.4","Tissue RNA - ovary [nTPM]":"45.4","Tissue RNA - pancreas [nTPM]":"265.9","Tissue RNA - parathyroid gland [nTPM]":"91.7","Tissue RNA - pituitary gland [nTPM]":"19.6","Tissue RNA - placenta [nTPM]":"141.1","Tissue RNA - pons [nTPM]":"101.6","Tissue RNA - prostate [nTPM]":"122.3","Tissue RNA - rectum [nTPM]":"201.5","Tissue RNA - retina [nTPM]":"60.3","Tissue RNA - salivary gland [nTPM]":"101.5","Tissue RNA - seminal vesicle [nTPM]":"56.0","Tissue RNA - skeletal muscle [nTPM]":"8905.8","Tissue RNA - skin 1 [nTPM]":"103.0","Tissue RNA - small intestine [nTPM]":"167.8","Tissue RNA - smooth muscle [nTPM]":"111.6","Tissue RNA - spinal cord [nTPM]":"94.6","Tissue RNA - spleen [nTPM]":"208.9","Tissue RNA - stomach 1 [nTPM]":"152.8","Tissue RNA - testis [nTPM]":"64.8","Tissue RNA - thalamus [nTPM]":"93.8","Tissue RNA - thymus [nTPM]":"203.0","Tissue RNA - thyroid gland [nTPM]":"88.8","Tissue RNA - tongue [nTPM]":"6106.5","Tissue RNA - tonsil [nTPM]":"287.2","Tissue RNA - urinary bladder [nTPM]":"183.2","Tissue RNA - vagina [nTPM]":"29.7","Tissue RNA - white matter [nTPM]":"98.2","Cell RNA - A-431 [nTPM]":"529.4","Cell RNA - A549 [nTPM]":"332.8","Cell RNA - AF22 [nTPM]":"306.1","Cell RNA - AN3-CA [nTPM]":"225.4","Cell RNA - ASC diff [nTPM]":"262.1","Cell RNA - ASC TERT1 [nTPM]":"341.1","Cell RNA - BEWO [nTPM]":"317.9","Cell RNA - BJ [nTPM]":"439.0","Cell RNA - BJ hTERT+ [nTPM]":"419.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"597.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"437.7","Cell RNA - CACO-2 [nTPM]":"596.1","Cell RNA - CAPAN-2 [nTPM]":"513.9","Cell RNA - Daudi [nTPM]":"414.6","Cell RNA - EFO-21 [nTPM]":"366.9","Cell RNA - fHDF\/TERT166 [nTPM]":"500.2","Cell RNA - GAMG [nTPM]":"206.4","Cell RNA - HaCaT [nTPM]":"472.1","Cell RNA - HAP1 [nTPM]":"320.0","Cell RNA - HBEC3-KT [nTPM]":"468.7","Cell RNA - HBF TERT88 [nTPM]":"485.8","Cell RNA - HDLM-2 [nTPM]":"315.7","Cell RNA - HEK 293 [nTPM]":"171.9","Cell RNA - HEL [nTPM]":"537.6","Cell RNA - HeLa [nTPM]":"234.1","Cell RNA - Hep G2 [nTPM]":"311.7","Cell RNA - HHSteC [nTPM]":"200.9","Cell RNA - HL-60 [nTPM]":"728.2","Cell RNA - HMC-1 [nTPM]":"627.5","Cell RNA - HSkMC [nTPM]":"260.0","Cell RNA - hTCEpi [nTPM]":"246.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"515.8","Cell RNA - hTERT-HME1 [nTPM]":"355.1","Cell RNA - hTERT-RPE1 [nTPM]":"224.9","Cell RNA - HUVEC TERT2 [nTPM]":"929.4","Cell RNA - JURKAT [nTPM]":"269.0","Cell RNA - K-562 [nTPM]":"411.8","Cell RNA - Karpas-707 [nTPM]":"429.7","Cell RNA - LHCN-M2 [nTPM]":"710.0","Cell RNA - MCF7 [nTPM]":"342.2","Cell RNA - MOLT-4 [nTPM]":"582.0","Cell RNA - NB-4 [nTPM]":"683.1","Cell RNA - NTERA-2 [nTPM]":"714.2","Cell RNA - OE19 [nTPM]":"775.9","Cell RNA - PC-3 [nTPM]":"515.9","Cell RNA - REH [nTPM]":"510.0","Cell RNA - RH-30 [nTPM]":"233.2","Cell RNA - RPMI-8226 [nTPM]":"574.9","Cell RNA - RPTEC TERT1 [nTPM]":"405.6","Cell RNA - RT4 [nTPM]":"387.4","Cell RNA - SCLC-21H [nTPM]":"234.4","Cell RNA - SH-SY5Y [nTPM]":"409.4","Cell RNA - SiHa [nTPM]":"360.0","Cell RNA - SK-BR-3 [nTPM]":"443.7","Cell RNA - SK-MEL-30 [nTPM]":"419.2","Cell RNA - SuSa [nTPM]":"303.9","Cell RNA - T-47d [nTPM]":"645.0","Cell RNA - THP-1 [nTPM]":"788.9","Cell RNA - TIME [nTPM]":"758.8","Cell RNA - U-138 MG [nTPM]":"558.8","Cell RNA - U-2 OS [nTPM]":"353.9","Cell RNA - U-2197 [nTPM]":"497.3","Cell RNA - U-251 MG [nTPM]":"711.1","Cell RNA - U-266\/70 [nTPM]":"332.4","Cell RNA - U-266\/84 [nTPM]":"623.0","Cell RNA - U-698 [nTPM]":"516.2","Cell RNA - U-87 MG [nTPM]":"490.7","Cell RNA - U-937 [nTPM]":"514.7","Cell RNA - WM-115 [nTPM]":"860.0","Blood RNA - basophil [nTPM]":"932.1","Blood RNA - classical monocyte [nTPM]":"743.2","Blood RNA - eosinophil [nTPM]":"1729.3","Blood RNA - gdT-cell [nTPM]":"547.2","Blood RNA - intermediate monocyte [nTPM]":"945.6","Blood RNA - MAIT T-cell [nTPM]":"480.1","Blood RNA - memory B-cell [nTPM]":"395.2","Blood RNA - memory CD4 T-cell [nTPM]":"464.0","Blood RNA - memory CD8 T-cell [nTPM]":"504.4","Blood RNA - myeloid DC [nTPM]":"792.6","Blood RNA - naive B-cell [nTPM]":"324.5","Blood RNA - naive CD4 T-cell [nTPM]":"347.2","Blood RNA - naive CD8 T-cell [nTPM]":"442.6","Blood RNA - neutrophil [nTPM]":"824.3","Blood RNA - NK-cell [nTPM]":"386.4","Blood RNA - non-classical monocyte [nTPM]":"1104.4","Blood RNA - plasmacytoid DC [nTPM]":"392.9","Blood RNA - T-reg [nTPM]":"551.5","Blood RNA - total PBMC [nTPM]":"2029.4","Brain RNA - amygdala [nTPM]":"95.0","Brain RNA - basal ganglia [nTPM]":"104.1","Brain RNA - cerebellum [nTPM]":"83.3","Brain RNA - cerebral cortex [nTPM]":"116.2","Brain RNA - hippocampal formation [nTPM]":"104.8","Brain RNA - hypothalamus [nTPM]":"101.5","Brain RNA - medulla oblongata [nTPM]":"96.6","Brain RNA - midbrain [nTPM]":"101.4","Brain RNA - pons [nTPM]":"101.6","Brain RNA - spinal cord [nTPM]":"94.6","Brain RNA - thalamus [nTPM]":"93.8","Brain RNA - white matter [nTPM]":"98.2","Single Cell Type RNA - Adipocytes [nTPM]":"346.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"621.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"343.2","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"318.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"149.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"227.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"169.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"127.5","Single Cell Type RNA - Bipolar cells [nTPM]":"84.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"135.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"88.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"85.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"125.8","Single Cell Type RNA - Club cells [nTPM]":"275.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"97.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"127.3","Single Cell Type RNA - dendritic cells [nTPM]":"475.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"494.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"105.7","Single Cell Type RNA - Ductal cells [nTPM]":"292.1","Single Cell Type RNA - Early spermatids [nTPM]":"72.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"353.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"191.1","Single Cell Type RNA - Endothelial cells [nTPM]":"395.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"141.0","Single Cell Type RNA - Erythroid cells [nTPM]":"189.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"65.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"347.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"331.0","Single Cell Type RNA - Fibroblasts [nTPM]":"170.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"245.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"474.2","Single Cell Type RNA - granulocytes [nTPM]":"531.3","Single Cell Type RNA - Granulosa cells [nTPM]":"119.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"200.3","Single Cell Type RNA - Hepatocytes [nTPM]":"110.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"559.1","Single Cell Type RNA - Horizontal cells [nTPM]":"304.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"291.2","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"355.6","Single Cell Type RNA - Langerhans cells [nTPM]":"504.7","Single Cell Type RNA - Late spermatids [nTPM]":"182.3","Single Cell Type RNA - Leydig cells [nTPM]":"46.6","Single Cell Type RNA - Macrophages [nTPM]":"648.3","Single Cell Type RNA - Melanocytes [nTPM]":"152.9","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"704.0","Single Cell Type RNA - Muller glia cells [nTPM]":"54.5","Single Cell Type RNA - NK-cells [nTPM]":"466.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"530.4","Single Cell Type RNA - Paneth cells [nTPM]":"363.9","Single Cell Type RNA - Peritubular cells [nTPM]":"29.7","Single Cell Type RNA - Plasma cells [nTPM]":"218.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"204.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"220.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"179.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"230.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"155.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"128.5","Single Cell Type RNA - Spermatocytes [nTPM]":"38.6","Single Cell Type RNA - Spermatogonia [nTPM]":"67.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"223.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"143.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"101.9","Single Cell Type RNA - T-cells [nTPM]":"422.6","Single Cell Type RNA - Theca cells [nTPM]":"119.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"302.1","Single Cell Type RNA - Urothelial cells [nTPM]":"324.6"},{"Gene":"TPR","Gene synonym":[],"Ensembl":"ENSG00000047410","Gene description":"Translocated promoter region, nuclear basket protein","Uniprot":["P12270"],"Chromosome":"1","Position":"186311652-186375693","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Mitosis","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"772.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019661","HPA019663","HPA024336"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019661":"AB_1858215","HPA019663":"AB_1858216","HPA024336":"AB_1858217"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.71e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"14.5","Tissue RNA - amygdala [nTPM]":"12.2","Tissue RNA - appendix [nTPM]":"23.4","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"28.9","Tissue RNA - breast [nTPM]":"19.7","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"17.6","Tissue RNA - choroid plexus [nTPM]":"18.4","Tissue RNA - colon [nTPM]":"17.6","Tissue RNA - duodenum [nTPM]":"15.5","Tissue RNA - endometrium 1 [nTPM]":"20.3","Tissue RNA - epididymis [nTPM]":"19.7","Tissue RNA - esophagus [nTPM]":"14.8","Tissue RNA - fallopian tube [nTPM]":"15.0","Tissue RNA - gallbladder [nTPM]":"16.1","Tissue RNA - heart muscle [nTPM]":"17.1","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"12.9","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"15.4","Tissue RNA - lung [nTPM]":"18.0","Tissue RNA - lymph node [nTPM]":"26.0","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"23.1","Tissue RNA - pancreas [nTPM]":"15.5","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"26.7","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"17.2","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"15.8","Tissue RNA - seminal vesicle [nTPM]":"17.6","Tissue RNA - skeletal muscle [nTPM]":"20.4","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"19.3","Tissue RNA - smooth muscle [nTPM]":"17.6","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"22.9","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"43.8","Tissue RNA - thalamus [nTPM]":"13.3","Tissue RNA - thymus [nTPM]":"31.0","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"22.3","Tissue RNA - tonsil [nTPM]":"26.0","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"55.9","Cell RNA - A549 [nTPM]":"46.7","Cell RNA - AF22 [nTPM]":"68.2","Cell RNA - AN3-CA [nTPM]":"39.8","Cell RNA - ASC diff [nTPM]":"53.4","Cell RNA - ASC TERT1 [nTPM]":"47.4","Cell RNA - BEWO [nTPM]":"73.2","Cell RNA - BJ [nTPM]":"62.0","Cell RNA - BJ hTERT+ [nTPM]":"41.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.4","Cell RNA - CACO-2 [nTPM]":"70.5","Cell RNA - CAPAN-2 [nTPM]":"45.9","Cell RNA - Daudi [nTPM]":"64.0","Cell RNA - EFO-21 [nTPM]":"47.1","Cell RNA - fHDF\/TERT166 [nTPM]":"42.1","Cell RNA - GAMG [nTPM]":"29.4","Cell RNA - HaCaT [nTPM]":"70.9","Cell RNA - HAP1 [nTPM]":"51.9","Cell RNA - HBEC3-KT [nTPM]":"42.4","Cell RNA - HBF TERT88 [nTPM]":"52.1","Cell RNA - HDLM-2 [nTPM]":"51.8","Cell RNA - HEK 293 [nTPM]":"58.6","Cell RNA - HEL [nTPM]":"86.8","Cell RNA - HeLa [nTPM]":"78.3","Cell RNA - Hep G2 [nTPM]":"49.7","Cell RNA - HHSteC [nTPM]":"28.7","Cell RNA - HL-60 [nTPM]":"93.1","Cell RNA - HMC-1 [nTPM]":"53.5","Cell RNA - HSkMC [nTPM]":"36.4","Cell RNA - hTCEpi [nTPM]":"25.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.4","Cell RNA - hTERT-HME1 [nTPM]":"49.4","Cell RNA - hTERT-RPE1 [nTPM]":"39.3","Cell RNA - HUVEC TERT2 [nTPM]":"51.3","Cell RNA - JURKAT [nTPM]":"36.5","Cell RNA - K-562 [nTPM]":"106.0","Cell RNA - Karpas-707 [nTPM]":"57.3","Cell RNA - LHCN-M2 [nTPM]":"45.8","Cell RNA - MCF7 [nTPM]":"47.5","Cell RNA - MOLT-4 [nTPM]":"46.2","Cell RNA - NB-4 [nTPM]":"24.5","Cell RNA - NTERA-2 [nTPM]":"76.1","Cell RNA - OE19 [nTPM]":"49.9","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"54.3","Cell RNA - RH-30 [nTPM]":"54.3","Cell RNA - RPMI-8226 [nTPM]":"56.5","Cell RNA - RPTEC TERT1 [nTPM]":"34.8","Cell RNA - RT4 [nTPM]":"65.0","Cell RNA - SCLC-21H [nTPM]":"37.7","Cell RNA - SH-SY5Y [nTPM]":"59.5","Cell RNA - SiHa [nTPM]":"72.9","Cell RNA - SK-BR-3 [nTPM]":"47.1","Cell RNA - SK-MEL-30 [nTPM]":"37.6","Cell RNA - SuSa [nTPM]":"92.5","Cell RNA - T-47d [nTPM]":"53.1","Cell RNA - THP-1 [nTPM]":"58.0","Cell RNA - TIME [nTPM]":"73.0","Cell RNA - U-138 MG [nTPM]":"42.5","Cell RNA - U-2 OS [nTPM]":"40.6","Cell RNA - U-2197 [nTPM]":"47.7","Cell RNA - U-251 MG [nTPM]":"76.6","Cell RNA - U-266\/70 [nTPM]":"63.2","Cell RNA - U-266\/84 [nTPM]":"77.6","Cell RNA - U-698 [nTPM]":"57.0","Cell RNA - U-87 MG [nTPM]":"27.5","Cell RNA - U-937 [nTPM]":"45.8","Cell RNA - WM-115 [nTPM]":"38.7","Blood RNA - basophil [nTPM]":"121.4","Blood RNA - classical monocyte [nTPM]":"34.1","Blood RNA - eosinophil [nTPM]":"69.0","Blood RNA - gdT-cell [nTPM]":"43.8","Blood RNA - intermediate monocyte [nTPM]":"30.0","Blood RNA - MAIT T-cell [nTPM]":"37.7","Blood RNA - memory B-cell [nTPM]":"48.9","Blood RNA - memory CD4 T-cell [nTPM]":"38.6","Blood RNA - memory CD8 T-cell [nTPM]":"36.8","Blood RNA - myeloid DC [nTPM]":"20.6","Blood RNA - naive B-cell [nTPM]":"55.4","Blood RNA - naive CD4 T-cell [nTPM]":"47.3","Blood RNA - naive CD8 T-cell [nTPM]":"32.8","Blood RNA - neutrophil [nTPM]":"145.7","Blood RNA - NK-cell [nTPM]":"33.0","Blood RNA - non-classical monocyte [nTPM]":"50.4","Blood RNA - plasmacytoid DC [nTPM]":"58.7","Blood RNA - T-reg [nTPM]":"49.1","Blood RNA - total PBMC [nTPM]":"17.3","Brain RNA - amygdala [nTPM]":"12.2","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"12.9","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"13.3","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"126.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"218.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"119.6","Single Cell Type RNA - Astrocytes [nTPM]":"43.1","Single Cell Type RNA - B-cells [nTPM]":"122.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"101.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"98.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"114.9","Single Cell Type RNA - Bipolar cells [nTPM]":"89.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"79.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"180.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"110.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"136.9","Single Cell Type RNA - dendritic cells [nTPM]":"136.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"51.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"107.1","Single Cell Type RNA - Early spermatids [nTPM]":"199.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"129.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"151.7","Single Cell Type RNA - Endothelial cells [nTPM]":"123.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.7","Single Cell Type RNA - Erythroid cells [nTPM]":"102.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"99.9","Single Cell Type RNA - Fibroblasts [nTPM]":"126.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"134.4","Single Cell Type RNA - granulocytes [nTPM]":"81.0","Single Cell Type RNA - Granulosa cells [nTPM]":"134.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.6","Single Cell Type RNA - Hepatocytes [nTPM]":"40.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.8","Single Cell Type RNA - Horizontal cells [nTPM]":"99.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"61.9","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"64.2","Single Cell Type RNA - Langerhans cells [nTPM]":"79.3","Single Cell Type RNA - Late spermatids [nTPM]":"50.4","Single Cell Type RNA - Leydig cells [nTPM]":"125.6","Single Cell Type RNA - Macrophages [nTPM]":"92.6","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"137.3","Single Cell Type RNA - Muller glia cells [nTPM]":"101.1","Single Cell Type RNA - NK-cells [nTPM]":"139.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"90.1","Single Cell Type RNA - Paneth cells [nTPM]":"56.7","Single Cell Type RNA - Peritubular cells [nTPM]":"117.4","Single Cell Type RNA - Plasma cells [nTPM]":"113.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"95.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"120.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.4","Single Cell Type RNA - Sertoli cells [nTPM]":"131.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"172.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"152.1","Single Cell Type RNA - Spermatocytes [nTPM]":"772.9","Single Cell Type RNA - Spermatogonia [nTPM]":"250.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"85.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"99.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"150.8","Single Cell Type RNA - T-cells [nTPM]":"145.8","Single Cell Type RNA - Theca cells [nTPM]":"160.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.7","Single Cell Type RNA - Urothelial cells [nTPM]":"96.0"},{"Gene":"VHL","Gene synonym":["VHL1"],"Ensembl":"ENSG00000134086","Gene description":"Von Hippel-Lindau tumor suppressor","Uniprot":["P40337"],"Chromosome":"3","Position":"10141778-10153667","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Congenital erythrocytosis","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"146.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031631","HPA031632","HPA068954"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031631":"AB_2673968","HPA031632":"AB_2673969","HPA068954":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.84e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"21.1","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"27.9","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"15.7","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"11.8","Tissue RNA - lymph node [nTPM]":"29.6","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"15.7","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"10.2","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"12.8","Tissue RNA - spinal cord [nTPM]":"9.6","Tissue RNA - spleen [nTPM]":"22.5","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"12.5","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"19.5","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"39.9","Cell RNA - AN3-CA [nTPM]":"24.6","Cell RNA - ASC diff [nTPM]":"36.0","Cell RNA - ASC TERT1 [nTPM]":"27.7","Cell RNA - BEWO [nTPM]":"146.5","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"24.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.5","Cell RNA - CACO-2 [nTPM]":"21.5","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"67.9","Cell RNA - EFO-21 [nTPM]":"22.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.0","Cell RNA - GAMG [nTPM]":"29.9","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"37.2","Cell RNA - HBEC3-KT [nTPM]":"23.6","Cell RNA - HBF TERT88 [nTPM]":"25.7","Cell RNA - HDLM-2 [nTPM]":"33.0","Cell RNA - HEK 293 [nTPM]":"33.7","Cell RNA - HEL [nTPM]":"52.7","Cell RNA - HeLa [nTPM]":"30.5","Cell RNA - Hep G2 [nTPM]":"30.6","Cell RNA - HHSteC [nTPM]":"34.3","Cell RNA - HL-60 [nTPM]":"47.3","Cell RNA - HMC-1 [nTPM]":"41.3","Cell RNA - HSkMC [nTPM]":"28.1","Cell RNA - hTCEpi [nTPM]":"26.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.0","Cell RNA - hTERT-HME1 [nTPM]":"35.1","Cell RNA - hTERT-RPE1 [nTPM]":"28.4","Cell RNA - HUVEC TERT2 [nTPM]":"24.6","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"48.3","Cell RNA - Karpas-707 [nTPM]":"50.3","Cell RNA - LHCN-M2 [nTPM]":"21.1","Cell RNA - MCF7 [nTPM]":"35.0","Cell RNA - MOLT-4 [nTPM]":"45.5","Cell RNA - NB-4 [nTPM]":"40.9","Cell RNA - NTERA-2 [nTPM]":"26.7","Cell RNA - OE19 [nTPM]":"21.1","Cell RNA - PC-3 [nTPM]":"23.4","Cell RNA - REH [nTPM]":"57.3","Cell RNA - RH-30 [nTPM]":"34.6","Cell RNA - RPMI-8226 [nTPM]":"34.6","Cell RNA - RPTEC TERT1 [nTPM]":"25.5","Cell RNA - RT4 [nTPM]":"48.7","Cell RNA - SCLC-21H [nTPM]":"15.0","Cell RNA - SH-SY5Y [nTPM]":"49.4","Cell RNA - SiHa [nTPM]":"35.0","Cell RNA - SK-BR-3 [nTPM]":"18.7","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"37.0","Cell RNA - THP-1 [nTPM]":"59.1","Cell RNA - TIME [nTPM]":"21.3","Cell RNA - U-138 MG [nTPM]":"20.8","Cell RNA - U-2 OS [nTPM]":"27.7","Cell RNA - U-2197 [nTPM]":"19.6","Cell RNA - U-251 MG [nTPM]":"26.8","Cell RNA - U-266\/70 [nTPM]":"35.7","Cell RNA - U-266\/84 [nTPM]":"78.1","Cell RNA - U-698 [nTPM]":"105.6","Cell RNA - U-87 MG [nTPM]":"23.2","Cell RNA - U-937 [nTPM]":"55.3","Cell RNA - WM-115 [nTPM]":"19.4","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"9.6","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"38.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.1","Single Cell Type RNA - Endothelial cells [nTPM]":"14.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"18.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"14.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.1","Single Cell Type RNA - Langerhans cells [nTPM]":"45.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"32.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"15.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.2","Single Cell Type RNA - T-cells [nTPM]":"23.5","Single Cell Type RNA - Theca cells [nTPM]":"21.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"25.9"}]