Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"	"Tissue RNA - adipose tissue [nTPM]"	"Tissue RNA - adrenal gland [nTPM]"	"Tissue RNA - amygdala [nTPM]"	"Tissue RNA - appendix [nTPM]"	"Tissue RNA - basal ganglia [nTPM]"	"Tissue RNA - bone marrow [nTPM]"	"Tissue RNA - breast [nTPM]"	"Tissue RNA - cerebellum [nTPM]"	"Tissue RNA - cerebral cortex [nTPM]"	"Tissue RNA - cervix [nTPM]"	"Tissue RNA - choroid plexus [nTPM]"	"Tissue RNA - colon [nTPM]"	"Tissue RNA - duodenum [nTPM]"	"Tissue RNA - endometrium 1 [nTPM]"	"Tissue RNA - epididymis [nTPM]"	"Tissue RNA - esophagus [nTPM]"	"Tissue RNA - fallopian tube [nTPM]"	"Tissue RNA - gallbladder [nTPM]"	"Tissue RNA - heart muscle [nTPM]"	"Tissue RNA - hippocampal formation [nTPM]"	"Tissue RNA - hypothalamus [nTPM]"	"Tissue RNA - kidney [nTPM]"	"Tissue RNA - liver [nTPM]"	"Tissue RNA - lung [nTPM]"	"Tissue RNA - lymph node [nTPM]"	"Tissue RNA - medulla oblongata [nTPM]"	"Tissue RNA - midbrain [nTPM]"	"Tissue RNA - ovary [nTPM]"	"Tissue RNA - pancreas [nTPM]"	"Tissue RNA - parathyroid gland [nTPM]"	"Tissue RNA - pituitary gland [nTPM]"	"Tissue RNA - placenta [nTPM]"	"Tissue RNA - pons [nTPM]"	"Tissue RNA - prostate [nTPM]"	"Tissue RNA - rectum [nTPM]"	"Tissue RNA - retina [nTPM]"	"Tissue RNA - salivary gland [nTPM]"	"Tissue RNA - seminal vesicle [nTPM]"	"Tissue RNA - skeletal muscle [nTPM]"	"Tissue RNA - skin 1 [nTPM]"	"Tissue RNA - small intestine [nTPM]"	"Tissue RNA - smooth muscle [nTPM]"	"Tissue RNA - spinal cord [nTPM]"	"Tissue RNA - spleen [nTPM]"	"Tissue RNA - stomach 1 [nTPM]"	"Tissue RNA - testis [nTPM]"	"Tissue RNA - thalamus [nTPM]"	"Tissue RNA - thymus [nTPM]"	"Tissue RNA - thyroid gland [nTPM]"	"Tissue RNA - tongue [nTPM]"	"Tissue RNA - tonsil [nTPM]"	"Tissue RNA - urinary bladder [nTPM]"	"Tissue RNA - vagina [nTPM]"	"Tissue RNA - white matter [nTPM]"	"Cell RNA - A-431 [nTPM]"	"Cell RNA - A549 [nTPM]"	"Cell RNA - AF22 [nTPM]"	"Cell RNA - AN3-CA [nTPM]"	"Cell RNA - ASC diff [nTPM]"	"Cell RNA - ASC TERT1 [nTPM]"	"Cell RNA - BEWO [nTPM]"	"Cell RNA - BJ [nTPM]"	"Cell RNA - BJ hTERT+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]"	"Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]"	"Cell RNA - CACO-2 [nTPM]"	"Cell RNA - CAPAN-2 [nTPM]"	"Cell RNA - Daudi [nTPM]"	"Cell RNA - EFO-21 [nTPM]"	"Cell RNA - fHDF/TERT166 [nTPM]"	"Cell RNA - GAMG [nTPM]"	"Cell RNA - HaCaT [nTPM]"	"Cell RNA - HAP1 [nTPM]"	"Cell RNA - HBEC3-KT [nTPM]"	"Cell RNA - HBF TERT88 [nTPM]"	"Cell RNA - HDLM-2 [nTPM]"	"Cell RNA - HEK 293 [nTPM]"	"Cell RNA - HEL [nTPM]"	"Cell RNA - HeLa [nTPM]"	"Cell RNA - Hep G2 [nTPM]"	"Cell RNA - HHSteC [nTPM]"	"Cell RNA - HL-60 [nTPM]"	"Cell RNA - HMC-1 [nTPM]"	"Cell RNA - HSkMC [nTPM]"	"Cell RNA - hTCEpi [nTPM]"	"Cell RNA - hTEC/SVTERT24-B [nTPM]"	"Cell RNA - hTERT-HME1 [nTPM]"	"Cell RNA - hTERT-RPE1 [nTPM]"	"Cell RNA - HUVEC TERT2 [nTPM]"	"Cell RNA - JURKAT [nTPM]"	"Cell RNA - K-562 [nTPM]"	"Cell RNA - Karpas-707 [nTPM]"	"Cell RNA - LHCN-M2 [nTPM]"	"Cell RNA - MCF7 [nTPM]"	"Cell RNA - MOLT-4 [nTPM]"	"Cell RNA - NB-4 [nTPM]"	"Cell RNA - NTERA-2 [nTPM]"	"Cell RNA - OE19 [nTPM]"	"Cell RNA - PC-3 [nTPM]"	"Cell RNA - REH [nTPM]"	"Cell RNA - RH-30 [nTPM]"	"Cell RNA - RPMI-8226 [nTPM]"	"Cell RNA - RPTEC TERT1 [nTPM]"	"Cell RNA - RT4 [nTPM]"	"Cell RNA - SCLC-21H [nTPM]"	"Cell RNA - SH-SY5Y [nTPM]"	"Cell RNA - SiHa [nTPM]"	"Cell RNA - SK-BR-3 [nTPM]"	"Cell RNA - SK-MEL-30 [nTPM]"	"Cell RNA - SuSa [nTPM]"	"Cell RNA - T-47d [nTPM]"	"Cell RNA - THP-1 [nTPM]"	"Cell RNA - TIME [nTPM]"	"Cell RNA - U-138 MG [nTPM]"	"Cell RNA - U-2 OS [nTPM]"	"Cell RNA - U-2197 [nTPM]"	"Cell RNA - U-251 MG [nTPM]"	"Cell RNA - U-266/70 [nTPM]"	"Cell RNA - U-266/84 [nTPM]"	"Cell RNA - U-698 [nTPM]"	"Cell RNA - U-87 MG [nTPM]"	"Cell RNA - U-937 [nTPM]"	"Cell RNA - WM-115 [nTPM]"	"Blood RNA - basophil [nTPM]"	"Blood RNA - classical monocyte [nTPM]"	"Blood RNA - eosinophil [nTPM]"	"Blood RNA - gdT-cell [nTPM]"	"Blood RNA - intermediate monocyte [nTPM]"	"Blood RNA - MAIT T-cell [nTPM]"	"Blood RNA - memory B-cell [nTPM]"	"Blood RNA - memory CD4 T-cell [nTPM]"	"Blood RNA - memory CD8 T-cell [nTPM]"	"Blood RNA - myeloid DC [nTPM]"	"Blood RNA - naive B-cell [nTPM]"	"Blood RNA - naive CD4 T-cell [nTPM]"	"Blood RNA - naive CD8 T-cell [nTPM]"	"Blood RNA - neutrophil [nTPM]"	"Blood RNA - NK-cell [nTPM]"	"Blood RNA - non-classical monocyte [nTPM]"	"Blood RNA - plasmacytoid DC [nTPM]"	"Blood RNA - T-reg [nTPM]"	"Blood RNA - total PBMC [nTPM]"	"Brain RNA - amygdala [nTPM]"	"Brain RNA - basal ganglia [nTPM]"	"Brain RNA - cerebellum [nTPM]"	"Brain RNA - cerebral cortex [nTPM]"	"Brain RNA - hippocampal formation [nTPM]"	"Brain RNA - hypothalamus [nTPM]"	"Brain RNA - medulla oblongata [nTPM]"	"Brain RNA - midbrain [nTPM]"	"Brain RNA - pons [nTPM]"	"Brain RNA - spinal cord [nTPM]"	"Brain RNA - thalamus [nTPM]"	"Brain RNA - white matter [nTPM]"	"Single Cell Type RNA - Adipocytes [nTPM]"	"Single Cell Type RNA - Alveolar cells type 1 [nTPM]"	"Single Cell Type RNA - Alveolar cells type 2 [nTPM]"	"Single Cell Type RNA - Astrocytes [nTPM]"	"Single Cell Type RNA - B-cells [nTPM]"	"Single Cell Type RNA - Basal keratinocytes [nTPM]"	"Single Cell Type RNA - Basal prostatic cells [nTPM]"	"Single Cell Type RNA - Basal respiratory cells [nTPM]"	"Single Cell Type RNA - Basal squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Bipolar cells [nTPM]"	"Single Cell Type RNA - Breast glandular cells [nTPM]"	"Single Cell Type RNA - Breast myoepithelial cells [nTPM]"	"Single Cell Type RNA - Cardiomyocytes [nTPM]"	"Single Cell Type RNA - Cholangiocytes [nTPM]"	"Single Cell Type RNA - Club cells [nTPM]"	"Single Cell Type RNA - Collecting duct cells [nTPM]"	"Single Cell Type RNA - Cone photoreceptor cells [nTPM]"	"Single Cell Type RNA - Cytotrophoblasts [nTPM]"	"Single Cell Type RNA - dendritic cells [nTPM]"	"Single Cell Type RNA - Distal enterocytes [nTPM]"	"Single Cell Type RNA - Distal tubular cells [nTPM]"	"Single Cell Type RNA - Ductal cells [nTPM]"	"Single Cell Type RNA - Early spermatids [nTPM]"	"Single Cell Type RNA - Endometrial ciliated cells [nTPM]"	"Single Cell Type RNA - Endometrial stromal cells [nTPM]"	"Single Cell Type RNA - Endothelial cells [nTPM]"	"Single Cell Type RNA - Enteroendocrine cells [nTPM]"	"Single Cell Type RNA - Erythroid cells [nTPM]"	"Single Cell Type RNA - Excitatory neurons [nTPM]"	"Single Cell Type RNA - Exocrine glandular cells [nTPM]"	"Single Cell Type RNA - Extravillous trophoblasts [nTPM]"	"Single Cell Type RNA - Fibroblasts [nTPM]"	"Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]"	"Single Cell Type RNA - Glandular and luminal cells [nTPM]"	"Single Cell Type RNA - granulocytes [nTPM]"	"Single Cell Type RNA - Granulosa cells [nTPM]"	"Single Cell Type RNA - Hepatic stellate cells [nTPM]"	"Single Cell Type RNA - Hepatocytes [nTPM]"	"Single Cell Type RNA - Hofbauer cells [nTPM]"	"Single Cell Type RNA - Horizontal cells [nTPM]"	"Single Cell Type RNA - Inhibitory neurons [nTPM]"	"Single Cell Type RNA - Intestinal goblet cells [nTPM]"	"Single Cell Type RNA - Ionocytes [nTPM]"	"Single Cell Type RNA - Kupffer cells [nTPM]"	"Single Cell Type RNA - Langerhans cells [nTPM]"	"Single Cell Type RNA - Late spermatids [nTPM]"	"Single Cell Type RNA - Leydig cells [nTPM]"	"Single Cell Type RNA - Macrophages [nTPM]"	"Single Cell Type RNA - Melanocytes [nTPM]"	"Single Cell Type RNA - Microglial cells [nTPM]"	"Single Cell Type RNA - monocytes [nTPM]"	"Single Cell Type RNA - Muller glia cells [nTPM]"	"Single Cell Type RNA - NK-cells [nTPM]"	"Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]"	"Single Cell Type RNA - Oligodendrocytes [nTPM]"	"Single Cell Type RNA - Pancreatic endocrine cells [nTPM]"	"Single Cell Type RNA - Paneth cells [nTPM]"	"Single Cell Type RNA - Peritubular cells [nTPM]"	"Single Cell Type RNA - Plasma cells [nTPM]"	"Single Cell Type RNA - Prostatic glandular cells [nTPM]"	"Single Cell Type RNA - Proximal enterocytes [nTPM]"	"Single Cell Type RNA - Proximal tubular cells [nTPM]"	"Single Cell Type RNA - Respiratory ciliated cells [nTPM]"	"Single Cell Type RNA - Rod photoreceptor cells [nTPM]"	"Single Cell Type RNA - Sertoli cells [nTPM]"	"Single Cell Type RNA - Skeletal myocytes [nTPM]"	"Single Cell Type RNA - Smooth muscle cells [nTPM]"	"Single Cell Type RNA - Spermatocytes [nTPM]"	"Single Cell Type RNA - Spermatogonia [nTPM]"	"Single Cell Type RNA - Squamous epithelial cells [nTPM]"	"Single Cell Type RNA - Suprabasal keratinocytes [nTPM]"	"Single Cell Type RNA - Syncytiotrophoblasts [nTPM]"	"Single Cell Type RNA - T-cells [nTPM]"	"Single Cell Type RNA - Theca cells [nTPM]"	"Single Cell Type RNA - Undifferentiated cells [nTPM]"	"Single Cell Type RNA - Urothelial cells [nTPM]"
AMER1	"FAM123B, FLJ39827, RP11-403E24.2, WTX"	ENSG00000184675	"APC membrane recruitment protein 1"	Q5JTC6	X	64185117-64205708	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Wnt signaling pathway"		"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"tongue: 15.3"	"Cell type enhanced"	"Detected in many"		"Sertoli cells: 6.6;Theca cells: 6.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in many"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"NTERA-2: 15.6"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA065214, HPA065265"	Approved		Supported	"Nuclear bodies,Vesicles,Plasma membrane"		NA	NA				"Cluster 13: Striated muscle - Muscle contraction"	"Cluster 5: NTERA-2 - Transcription"	"Cluster 10: Non-specific - Unknown function"	"Nuclear bodies"	"Vesicles, Plasma membrane"	"HPA065214: AB_2685435, HPA065265: AB_2685450"	"unprognostic (1.56e-2)"	"unprognostic (8.85e-2)"	"unprognostic (6.86e-2)"	"unprognostic (2.74e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.86e-1)"	"unprognostic (3.57e-2)"	"unprognostic (1.48e-1)"	"unprognostic (8.02e-2)"	"unprognostic (1.75e-1)"	"unprognostic (6.31e-2)"	"unprognostic (3.43e-1)"	"unprognostic (4.69e-4)"	"unprognostic (1.26e-1)"	"unprognostic (1.13e-1)"	"unprognostic (6.19e-2)"	"unprognostic (2.89e-1)"	1.1	1.4	1.6	1.3	1.5	1.2	1.3	1.8	1.6	1.9	0.1	1.5	1.5	1.9	4.0	2.8	2.2	1.0	1.3	1.0	1.6	1.8	2.1	1.2	1.2	1.5	1.4	6.3	2.0	1.6	0.7	0.8	1.5	1.7	1.3	1.3	2.2	2.2	4.1	2.2	1.3	2.8	0.7	1.3	1.6	0.4	1.9	1.6	1.4	15.3	1.6	1.3	1.3	1.0	3.1	2.2	5.8	4.6	2.2	2.1	4.7	1.4	1.2	2.1	1.3	7.3	1.1	5.9	1.8	3.0	1.6	4.3	12.5	4.1	2.0	2.5	2.5	3.7	4.9	4.9	1.6	7.7	0.9	3.0	5.3	1.6	3.2	1.7	1.2	4.6	5.6	5.9	1.1	3.7	5.2	4.0	15.6	4.0	4.4	11.7	9.4	4.3	0.9	1.0	2.6	3.9	3.7	5.0	1.9	4.8	1.6	2.1	0.8	2.5	5.8	6.7	1.9	3.0	2.2	4.4	1.2	8.7	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	1.6	1.5	1.8	1.6	1.0	1.6	1.5	1.4	1.5	0.7	1.9	1.0	0.9	0.0	0.0	1.0	1.5	2.2	0.6	0.9	2.8	5.0	1.7	1.5	2.6	4.3	0.3	0.0	2.1	1.1	3.4	1.1	0.0	1.2	0.1	3.3	2.6	1.5	1.2	0.8	0.8	1.6	0.8	1.8	3.6	2.0	0.0	3.9	1.4	2.6	0.4	0.0	1.3	1.0	0.0	1.0	0.3	0.2	2.5	0.5	1.8	1.0	1.2	0.2	0.0	1.0	0.6	0.7	0.5	4.1	2.4	1.2	0.8	0.8	0.0	1.0	6.6	2.3	4.4	0.0	0.2	3.6	2.6	0.7	0.9	6.4	1.6	0.7
CDKN2A	"ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf"	ENSG00000147889	"Cyclin dependent kinase inhibitor 2A"	"P42771, Q8N726"	9	21967752-21995301	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway"	DNA-binding	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"choroid plexus: 31.7;pituitary gland: 33.7"	"Cell type enhanced"	"Detected in many"		"Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9"	"Cancer enhanced"	"Detected in all"		"cervical cancer: 49.9;ovarian cancer: 57.6"	"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"T-reg: 37.4"	"Group enriched"	"Detected in many"	6	"B-cells: 15.6;T-cells: 37.4"	"Cell line enhanced"	"Detected in many"		"CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7"					"Low region specificity"	"Detected in some"			"CAB000093, CAB000445, CAB018232, HPA047838"	Enhanced		Supported	Nucleoli		NA	NA		18000	"Cluster 4: T-regs - Cell cycle regulation"	"Cluster 26: Pituitary gland - Hormone signaling"	"Cluster 19: HEK293 & PC-3 - Transcription regulation"	"Cluster 16: Pancreatic endocrine cells - Mixed function"	Nucleoli		"CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174"	"unprognostic (3.41e-2)"	"unprognostic (4.51e-2)"	"unprognostic (3.00e-3)"	"prognostic unfavorable (1.82e-7)"	"unprognostic (5.22e-2)"	"prognostic favorable (5.19e-4)"	"prognostic unfavorable (2.17e-4)"	"unprognostic (1.25e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.71e-1)"	"unprognostic (1.56e-2)"	"prognostic unfavorable (5.76e-7)"	"unprognostic (9.41e-2)"	"unprognostic (1.22e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.55e-1)"	3.7	10.1	7.4	1.7	8.3	1.3	3.1	5.9	8.5	1.1	31.7	1.9	0.8	0.7	1.0	7.4	2.2	0.5	0.7	6.7	6.4	0.5	0.7	2.3	2.1	7.4	5.8	0.8	1.5	2.1	33.7	2.6	7.2	2.1	0.7	0.1	1.6	1.6	0.6	0.9	3.6	0.3	6.2	5.5	3.9	14.8	8.0	2.1	1.3	0.0	2.5	2.4	2.3	9.2	11.8	0.0	1.7	82.2	0.8	0.9	39.1	15.9	0.0	111.7	196.0	19.1	289.2	47.1	167.7	9.5	0.0	36.0	34.3	211.0	91.4	212.2	389.7	0.1	311.1	13.6	8.8	22.4	17.3	21.2	0.0	112.2	61.9	236.3	11.7	0.0	0.1	188.4	105.7	0.8	1.9	0.0	2.6	24.2	185.9	0.2	80.2	166.3	23.4	0.0	195.2	14.0	219.9	36.6	318.7	9.4	42.8	0.7	39.5	0.9	2.6	0.3	0.5	84.7	49.6	177.8	0.2	62.9	1.0	1.5	2.1	0.3	9.9	1.3	14.1	11.1	11.4	17.6	0.3	15.6	0.6	6.7	0.5	0.8	4.2	0.0	37.4	3.6	7.4	8.3	5.9	8.5	6.7	6.4	7.4	5.8	7.2	6.2	8.0	9.2	1.6	0.0	0.0	1.0	11.5	1.8	2.3	170.1	0.0	0.6	6.1	10.4	4.2	0.0	145.9	11.0	0.0	27.9	6.2	8.1	0.0	29.7	227.5	36.4	6.7	2.6	70.9	0.0	1.2	26.4	43.8	7.7	0.0	6.2	4.5	4.6	1.4	0.3	7.6	0.0	3.5	6.3	122.1	10.5	4.2	447.9	3.1	2.9	8.8	7.5	16.2	0.9	5.2	4.5	6.6	417.7	12.1	1.9	38.7	35.4	32.8	0.0	221.9	0.1	0.0	1.1	20.8	7.2	6.2	7.2	0.4	9.2	12.7	11.0	3.8	54.4
CTNNB1	"armadillo, beta-catenin, CTNNB"	ENSG00000168036	"Catenin beta 1"	P35222	3	41194741-41260096	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway"	Activator	"Cancer-related genes, Disease variant, Mental retardation"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Syncytiotrophoblasts: 539.5"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000108, CAB001950, HPA029159, HPA029160"	Supported		Enhanced	"Plasma membrane"		NA	NA		2000000	"Cluster 39: Non-specific - mRNA processing"	"Cluster 37: Intestine - Unknown function"	"Cluster 33: SK-MEL-30 - Melanocyte processes"	"Cluster 41: Macrophages - Immune response"	"Plasma membrane"		"CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996"	"unprognostic (2.47e-1)"	"unprognostic (3.48e-2)"	"prognostic favorable (7.54e-4)"	"unprognostic (1.61e-1)"	"unprognostic (9.55e-2)"	"unprognostic (1.05e-2)"	"unprognostic (3.20e-3)"	"unprognostic (2.79e-1)"	"unprognostic (1.57e-1)"	"unprognostic (1.80e-2)"	"unprognostic (1.88e-2)"	"unprognostic (9.05e-2)"	"unprognostic (1.97e-3)"	"unprognostic (1.82e-2)"	"unprognostic (1.17e-1)"	"unprognostic (2.61e-1)"	"unprognostic (9.79e-2)"	130.8	112.2	106.7	98.7	85.3	162.4	194.3	147.8	87.5	179.4	94.7	141.2	136.9	149.4	84.4	113.7	131.0	121.8	109.9	88.1	105.3	106.5	147.9	132.9	81.9	101.3	112.9	173.9	93.3	137.2	84.7	200.0	94.0	132.3	134.5	88.8	110.9	126.3	87.3	99.0	142.9	178.4	104.9	92.5	81.8	59.5	129.4	95.6	140.6	89.9	99.5	158.3	109.3	108.4	161.6	210.0	423.6	242.8	226.9	184.7	333.8	179.6	249.7	288.2	284.3	146.3	224.0	131.7	157.8	314.1	129.0	119.6	315.8	510.0	306.2	123.3	215.7	215.5	261.0	523.7	169.5	121.8	99.1	271.6	226.7	345.5	208.7	235.7	258.1	63.0	153.7	80.3	324.1	161.8	87.3	68.3	397.2	211.0	159.3	64.9	281.9	88.3	177.9	494.8	102.9	172.4	296.2	147.1	809.4	509.8	242.1	248.6	340.8	217.1	163.6	139.3	264.0	50.7	82.7	138.4	221.5	150.5	369.7	4.7	7.3	6.4	9.2	12.3	10.9	7.7	8.6	10.1	11.8	8.0	8.6	9.4	6.6	9.6	12.6	10.0	10.8	5.6	106.7	85.3	147.8	87.5	88.1	105.3	101.3	112.9	94.0	104.9	129.4	108.4	171.7	137.8	179.5	58.1	71.7	213.5	130.1	75.3	116.1	40.7	232.5	168.1	84.7	90.1	119.2	62.5	33.3	318.9	99.0	251.6	35.2	132.2	11.0	90.3	125.9	187.3	93.8	43.8	50.9	78.5	115.6	116.8	53.0	95.5	116.6	137.0	139.2	172.5	115.1	13.5	82.4	145.9	42.7	154.6	228.1	9.5	59.7	161.1	202.7	124.6	98.3	89.2	49.4	70.9	62.9	139.8	249.5	86.9	55.5	128.3	160.3	93.2	96.1	62.0	46.0	175.6	137.3	78.4	40.1	70.9	174.9	539.5	77.0	245.6	189.6	127.9
DAPK1	"DAPK, ROCO3"	ENSG00000196730	"Death associated protein kinase 1"	P53355	9	87497228-87708634	"Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted membrane proteins"	"Apoptosis, Translation regulation"	"Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 139.1;Excitatory neurons: 120.2;Inhibitory neurons: 155.9;Kupffer cells: 85.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"classical monocyte: 6.7;eosinophil: 8.7;intermediate monocyte: 14.0;myeloid DC: 4.8;non-classical monocyte: 15.2;plasmacytoid DC: 6.2"	"Group enriched"	"Detected in many"	56	"dendritic cells: 6.2;granulocytes: 8.7;monocytes: 15.2"	"Cell line enhanced"	"Detected in many"		"HMC-1: 97.6;HUVEC TERT2: 56.3"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB037302, HPA040472, HPA048436"	Approved		Approved	Centrosome		NA	NA			"Cluster 51: Monocytes - Innate immune response"	"Cluster 29: Non-specific - Vesicular transport"	"Cluster 3: HMC-1 - Innate immune response"	"Cluster 8: Neurons & Oligodendrocytes - Synaptic function"	Centrosome		"CAB037302: AB_1078622, HPA040472: AB_2677001, HPA048436: AB_2680390"	"unprognostic (2.55e-1)"	"unprognostic (1.47e-1)"	"prognostic unfavorable (2.48e-5)"	"unprognostic (2.77e-1)"	"unprognostic (1.74e-1)"	"unprognostic (3.47e-2)"	"unprognostic (1.74e-1)"	"unprognostic (1.75e-1)"	"unprognostic (1.88e-2)"	"unprognostic (5.77e-3)"	"unprognostic (2.19e-2)"	"unprognostic (2.77e-3)"	"unprognostic (8.31e-3)"	"unprognostic (8.76e-2)"	"unprognostic (2.40e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.09e-3)"	22.9	5.9	12.1	11.8	16.4	5.4	5.9	2.2	20.5	9.6	12.6	27.1	10.1	7.9	18.8	5.5	15.2	28.0	5.2	22.8	7.6	22.0	27.6	37.5	12.5	7.6	7.6	46.0	29.2	6.7	23.4	27.3	13.8	5.2	9.2	11.5	13.7	8.5	1.8	5.0	14.4	9.4	7.8	22.8	19.5	8.1	8.6	41.8	9.8	2.3	6.8	14.5	3.8	7.5	0.0	47.5	22.5	15.8	0.7	0.3	35.4	3.1	4.4	18.3	20.4	6.8	0.3	0.4	4.7	1.0	0.2	43.9	13.9	1.0	7.9	0.4	11.4	23.4	6.6	23.7	19.5	0.0	97.6	1.4	7.5	3.5	1.4	28.5	56.3	6.5	17.8	9.6	15.4	1.5	7.0	0.0	25.4	44.4	0.0	2.0	19.8	0.1	50.6	47.6	10.2	11.3	0.0	4.6	20.1	32.7	0.0	15.2	0.4	0.1	0.3	0.1	0.1	36.9	8.1	0.0	0.2	6.4	3.0	1.7	6.7	8.7	0.0	14.0	0.0	0.1	0.0	0.0	4.8	0.0	0.0	0.1	2.0	0.1	15.2	6.2	0.0	3.0	12.1	16.4	2.2	20.5	22.8	7.6	7.6	7.6	13.8	7.8	8.6	7.5	8.8	51.3	72.2	139.1	2.7	3.6	0.8	1.2	0.6	19.4	1.3	2.3	2.4	31.5	24.3	22.0	2.1	6.8	9.5	1.1	1.9	33.8	1.8	30.2	7.9	17.3	0.0	12.8	120.2	23.0	19.0	12.3	26.5	58.6	24.1	22.1	68.9	20.8	22.7	18.5	155.9	9.3	0.0	85.7	18.3	3.1	14.9	57.1	12.4	18.7	41.2	14.6	2.1	6.6	4.7	35.8	1.9	13.5	6.2	3.2	9.6	7.0	10.2	2.9	0.0	1.5	3.9	3.4	7.2	1.6	3.1	14.2	2.8	3.4	3.7	14.9
EGFR	"ERBB, ERBB1"	ENSG00000146648	"Epidermal growth factor receptor"	P00533	7	55019017-55211628	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	"Host-virus interaction"	"Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8"	"Cancer enhanced"	"Detected in all"		"glioma: 136.0"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enriched"	"Detected in many"	13	"A-431: 5282.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000035, HPA001200, HPA018530, CAB068186, CAB073534"	Enhanced		Enhanced	"Plasma membrane,Cell Junctions"	"Secreted to blood"	NA	NA	4740000	88000000		"Cluster 31: Skin - Epidermis development"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 50: Fibroblasts - ECM organization"	"Plasma membrane, Cell Junctions"		"CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044"	"unprognostic (2.62e-2)"	"unprognostic (9.56e-3)"	"unprognostic (1.59e-1)"	"unprognostic (7.51e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.27e-2)"	"unprognostic (6.11e-2)"	"unprognostic (4.88e-2)"	"unprognostic (2.85e-2)"	"unprognostic (3.30e-3)"	"unprognostic (1.78e-3)"	"unprognostic (1.04e-1)"	"unprognostic (1.93e-3)"	"unprognostic (6.98e-3)"	"unprognostic (1.72e-1)"	"unprognostic (6.62e-2)"	"prognostic unfavorable (2.04e-5)"	27.9	11.4	12.6	4.0	18.3	0.0	20.0	16.6	9.7	20.4	10.5	12.2	5.7	11.4	10.3	23.5	13.9	9.0	7.1	6.3	10.3	11.6	35.3	14.9	2.5	10.4	19.0	15.1	15.8	3.5	2.9	67.9	8.9	16.2	10.7	10.2	22.1	15.0	10.9	51.0	9.5	9.3	7.5	5.1	11.1	4.2	22.6	12.8	20.6	20.6	8.3	14.7	24.1	6.3	5282.1	61.9	16.5	22.4	102.7	63.5	16.7	47.9	68.7	30.8	23.8	11.5	54.2	2.7	11.4	43.8	130.7	197.1	0.4	230.2	37.1	2.2	3.6	0.1	27.3	3.4	27.0	0.0	0.2	31.2	205.4	74.1	409.9	45.5	4.0	0.0	0.0	0.5	68.0	3.0	0.1	0.1	5.1	21.2	30.4	0.1	9.1	0.2	38.1	52.6	0.8	20.0	42.7	50.6	9.3	16.8	4.9	12.0	15.6	27.1	7.2	215.7	45.8	0.1	4.8	3.1	37.9	1.6	8.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	12.6	18.3	16.6	9.7	6.3	10.3	10.4	19.0	8.9	7.5	22.6	6.3	16.4	96.1	49.9	147.6	1.2	85.8	77.1	101.5	116.1	3.5	12.1	30.4	11.1	47.1	50.6	22.0	6.2	287.9	0.0	45.9	0.0	32.9	4.9	25.9	57.2	12.5	4.2	8.0	1.2	24.3	37.1	91.6	22.4	39.8	0.0	50.6	6.8	79.5	28.3	0.0	107.5	21.6	48.8	7.7	11.6	5.8	128.3	1.9	17.8	40.3	1.6	90.0	0.0	63.3	1.4	54.8	19.9	133.5	0.0	75.4	14.1	13.4	21.7	3.8	78.9	251.2	34.7	2.4	2.5	73.3	89.9	376.8	2.2	41.9	24.9	55.8
ERBB2	"CD340, HER-2, HER2, NEU, NGL"	ENSG00000141736	"Erb-b2 receptor tyrosine kinase 2"	P04626	17	39687914-39730426	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins"	"Transcription, Transcription regulation"	"Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Collecting duct cells: 136.1;Distal enterocytes: 111.0;Proximal enterocytes: 121.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"gdT-cell: 5.0"	"Lineage enriched"	"Detected in many"	4	"T-cells: 5.0"	"Group enriched"	"Detected in many"	41	"OE19: 6565.0;SK-BR-3: 3115.9"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555"	Enhanced		Enhanced	"Plasma membrane,Cytosol"		NA	NA		980000	"Cluster 36: GdT-cells - Adaptive immune response"	"Cluster 7: Kidney - Transmembrane transport"	"Cluster 21: OE19 - Mitochondria"	"Cluster 53: Intestinal epithelial cells - Unknown function"	"Plasma membrane"	Cytosol	"CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500"	"unprognostic (1.97e-1)"	"unprognostic (6.60e-3)"	"unprognostic (6.21e-2)"	"prognostic unfavorable (8.99e-8)"	"unprognostic (2.96e-2)"	"unprognostic (1.40e-2)"	"unprognostic (1.97e-2)"	"unprognostic (9.04e-2)"	"unprognostic (1.79e-2)"	"unprognostic (1.20e-3)"	"prognostic unfavorable (9.17e-4)"	"unprognostic (3.92e-1)"	"prognostic favorable (2.41e-14)"	"unprognostic (9.29e-2)"	"unprognostic (1.40e-1)"	"unprognostic (3.75e-2)"	"unprognostic (1.96e-1)"	13.0	5.4	16.1	12.1	20.5	1.6	56.0	14.3	13.1	37.6	23.3	68.2	63.6	25.2	26.6	102.4	64.2	31.0	57.0	13.3	16.0	73.5	31.1	36.2	4.8	22.4	22.7	23.9	37.6	81.7	17.3	27.0	17.1	55.6	48.5	8.1	68.7	50.5	20.7	91.0	67.3	25.0	18.5	6.9	49.7	11.7	15.4	7.4	56.5	15.0	28.0	40.0	52.9	16.4	38.7	45.7	50.4	31.7	59.3	41.2	67.7	27.2	44.9	58.6	48.9	34.4	102.7	2.9	54.6	62.7	31.5	117.6	2.8	61.2	26.9	5.2	38.6	1.8	36.0	56.3	35.3	0.9	1.0	41.0	56.6	36.2	21.9	56.2	24.4	1.9	6.2	2.4	43.3	59.4	7.1	3.0	90.7	6565.0	11.7	3.9	20.5	5.4	58.9	118.9	9.4	2.6	51.5	3115.9	16.9	62.2	88.1	2.2	2.9	30.2	37.7	37.7	17.6	5.3	3.3	3.6	3.0	0.9	98.5	1.1	0.2	0.4	5.0	0.1	0.3	0.6	0.2	1.4	0.2	0.6	0.5	1.4	1.2	0.4	0.1	0.1	0.2	1.7	16.1	20.5	14.3	13.1	13.3	16.0	22.4	22.7	17.1	18.5	15.4	16.4	3.9	41.7	40.1	12.7	2.2	14.0	19.0	37.1	17.6	4.6	62.7	34.9	20.7	32.9	43.8	136.1	12.5	12.0	5.1	111.0	7.9	30.9	0.3	48.7	13.9	6.1	15.6	1.3	0.9	25.5	84.8	15.7	53.5	61.3	0.0	20.3	11.7	10.7	4.0	6.7	1.0	47.5	42.7	2.2	3.1	1.0	18.3	1.7	10.6	1.0	1.2	24.1	26.8	2.0	1.0	32.5	54.8	23.0	1.1	34.9	121.7	19.5	42.0	5.8	0.0	13.1	12.7	6.8	5.7	43.5	18.9	22.7	2.8	4.4	75.4	31.3
FGFR3	"ACH, CD333, CEK2, JTK4"	ENSG00000068078	"Fibroblast growth factor receptor 3"	P22607	4	1793293-1808872	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"	Apoptosis	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 148.3;esophagus: 139.7;skin 1: 271.5"	"Cell type enhanced"	"Detected in many"		"Astrocytes: 410.4;Basal keratinocytes: 103.8;Cholangiocytes: 91.5;Suprabasal keratinocytes: 88.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"CACO-2: 48.2;HaCaT: 34.9;Hep G2: 80.6;NTERA-2: 36.1;RT4: 64.1"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004231, HPA067204"	Enhanced		Supported	"Endoplasmic reticulum"	"Secreted - unknown location"	NA	NA		2500000		"Cluster 27: Brain & Skin - Unknown function"	"Cluster 37: Hep G2 - Hepatocyte cell processes"	"Cluster 64: Astrocytes - Nervous system maintenance"	"Endoplasmic reticulum"		"CAB004231: AB_627596, HPA067204: AB_2685804"	"unprognostic (1.34e-1)"	"unprognostic (5.29e-3)"	"unprognostic (1.49e-1)"	"prognostic unfavorable (3.77e-4)"	"unprognostic (5.90e-2)"	"unprognostic (1.24e-3)"	"unprognostic (7.22e-2)"	"unprognostic (2.54e-1)"	"unprognostic (1.99e-1)"	"unprognostic (2.17e-1)"	"unprognostic (1.38e-1)"	"unprognostic (2.88e-2)"	"unprognostic (1.30e-1)"	"unprognostic (9.11e-3)"	"unprognostic (1.98e-1)"	"unprognostic (4.74e-2)"	"unprognostic (1.97e-1)"	1.6	1.6	118.0	1.5	140.6	1.4	5.5	115.6	104.0	23.7	37.4	12.2	19.5	1.5	2.8	139.7	2.2	7.9	4.8	100.8	107.6	39.3	40.7	7.4	0.4	144.7	129.2	0.5	76.4	0.2	16.1	9.3	109.8	13.8	5.2	0.2	20.2	15.0	1.3	271.5	14.7	0.4	108.9	4.0	7.8	17.6	148.3	1.7	1.5	0.9	11.1	23.1	60.9	81.2	0.0	3.8	19.5	5.6	0.0	0.3	22.1	2.4	0.3	0.8	0.4	48.2	1.0	0.0	17.8	0.7	0.7	34.9	5.5	0.3	0.3	0.2	19.3	14.2	3.9	80.6	0.1	0.0	0.6	0.0	10.9	0.2	0.1	0.1	0.1	2.3	16.7	0.1	0.0	23.9	0.8	0.5	36.1	19.5	0.1	1.2	1.0	0.3	2.8	64.1	5.7	1.6	1.9	4.0	0.0	22.2	20.4	2.5	1.0	0.0	2.1	0.5	1.6	0.1	0.0	0.0	0.2	1.7	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	118.0	140.6	115.6	104.0	100.8	107.6	144.7	129.2	109.8	108.9	148.3	81.2	2.2	0.0	32.5	410.4	1.1	103.8	4.1	29.8	23.9	0.0	4.8	1.5	3.1	91.5	37.6	14.7	0.0	0.5	1.6	36.1	0.0	5.0	7.9	3.0	1.7	3.4	4.2	0.0	0.5	0.7	12.0	3.2	3.6	4.0	0.0	0.1	16.1	30.4	0.6	0.0	1.3	20.7	4.1	1.2	6.5	1.3	0.6	0.6	12.4	14.0	0.6	0.1	0.0	34.2	2.2	0.4	18.0	0.4	0.0	4.2	21.2	9.9	9.8	0.6	0.0	0.7	2.9	0.4	25.9	55.0	88.7	0.8	0.7	0.1	17.0	12.8
FH		ENSG00000091483	"Fumarate hydratase"	P07954	1	241497603-241519755	"Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"DNA damage, DNA repair, Tricarboxylic acid cycle"	Lyase	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"liver: 276.4"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 173.5;Early spermatids: 226.0;Syncytiotrophoblasts: 166.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017785, HPA025770, HPA025948, HPA027341"	Enhanced	Supported	Enhanced	Mitochondria		NA	NA		1800000	"Cluster 44: Non-specific - Transcription"	"Cluster 8: Non-specific - Mitochondria"	"Cluster 25: RPMI-8226 - Immune response"	"Cluster 39: Non-specific - Basic cellular processes"	Mitochondria		"CAB017785: , HPA025770: AB_10599603, HPA025948: AB_10602177, HPA027341: AB_10601222"	"unprognostic (1.03e-2)"	"unprognostic (3.82e-2)"	"unprognostic (9.46e-3)"	"unprognostic (2.18e-1)"	"unprognostic (2.10e-1)"	"unprognostic (2.07e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.55e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.85e-2)"	"unprognostic (1.27e-2)"	"unprognostic (1.09e-1)"	"prognostic favorable (2.76e-7)"	"unprognostic (1.05e-1)"	"unprognostic (1.05e-1)"	"unprognostic (4.41e-2)"	"unprognostic (1.24e-2)"	43.4	75.2	30.4	31.0	33.3	31.4	37.3	33.5	42.0	28.9	43.9	66.8	68.2	36.9	26.1	51.1	27.9	23.7	179.0	33.9	33.1	101.8	276.4	26.4	30.0	31.8	31.0	24.9	38.1	95.0	31.1	32.1	32.1	33.5	69.0	58.8	42.0	38.4	213.4	40.3	59.1	42.0	32.4	30.1	53.6	44.4	32.7	31.3	34.6	229.3	40.4	37.5	33.7	33.0	129.2	105.6	97.9	89.0	93.9	110.0	154.9	155.7	121.1	171.6	107.1	152.2	78.0	81.1	100.3	119.9	75.0	178.4	151.7	115.8	148.4	93.5	48.9	76.3	102.2	131.4	84.1	180.2	66.7	80.2	70.7	96.6	108.0	60.2	107.2	175.8	236.3	101.7	126.9	64.3	156.6	120.1	104.5	186.2	223.6	127.4	107.2	365.7	167.4	107.6	125.4	108.4	131.1	153.3	104.0	67.2	117.1	120.9	106.5	76.6	98.9	137.0	264.0	90.3	103.7	97.3	85.7	203.5	112.6	11.9	22.8	4.9	16.1	33.3	21.0	27.2	18.8	15.1	46.7	25.1	22.3	21.1	1.3	18.3	29.1	23.1	23.8	16.7	30.4	33.3	33.5	42.0	33.9	33.1	31.8	31.0	32.1	32.4	32.7	33.0	17.1	38.5	30.2	9.4	25.0	20.0	24.6	69.5	17.1	24.7	19.9	17.5	173.5	35.8	40.0	23.9	14.6	101.6	13.7	44.0	78.2	60.4	226.0	25.4	23.5	18.6	18.0	37.7	12.7	45.0	58.7	25.5	26.5	25.4	19.0	24.9	13.6	80.4	50.7	35.3	14.9	40.6	48.8	18.5	14.4	37.4	23.9	23.9	24.9	8.4	27.9	35.0	10.3	8.0	14.4	29.4	35.7	26.7	41.3	19.0	66.1	86.0	29.2	39.1	39.5	27.7	67.9	84.7	47.1	32.1	18.6	166.1	14.9	48.4	74.2	22.8
FLCN	"BHD, DENND8B, MGC17998, MGC23445"	ENSG00000154803	Folliculin	Q8NFG4	17	17212212-17237188	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Cone photoreceptor cells: 79.2;Erythroid cells: 81.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB015158, HPA028760"	Supported		Supported	"Plasma membrane,Cytosol"		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 72: Non-specific - Transcription"	"Cluster 18: U-2197 - ECM organization"	"Cluster 6: Erythroid cells - Oxygen transport"	Cytosol	"Plasma membrane"	"CAB015158: AB_2231645, HPA028760: AB_10601323"	"unprognostic (1.99e-1)"	"unprognostic (1.77e-1)"	"unprognostic (1.53e-2)"	"unprognostic (1.74e-1)"	"unprognostic (3.85e-2)"	"unprognostic (3.69e-1)"	"unprognostic (3.73e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.58e-2)"	"unprognostic (3.90e-1)"	"prognostic favorable (4.49e-4)"	"unprognostic (6.45e-3)"	"unprognostic (2.55e-3)"	"unprognostic (1.92e-1)"	"unprognostic (9.71e-2)"	"unprognostic (2.62e-2)"	"unprognostic (1.65e-1)"	21.8	19.0	19.0	10.7	25.9	17.7	18.9	27.3	31.6	42.5	18.3	43.7	23.3	37.0	14.5	13.8	25.2	17.0	29.2	31.9	14.0	15.3	28.9	26.8	12.4	21.3	15.2	35.3	15.2	13.1	28.6	13.1	22.0	27.1	10.2	7.2	16.4	13.7	42.7	19.3	26.8	14.5	14.0	29.2	22.4	21.0	19.3	8.6	23.8	18.4	8.0	28.2	25.5	28.3	12.0	30.4	11.5	14.9	36.4	20.6	15.8	11.8	19.1	18.0	24.3	24.3	10.4	6.3	13.8	14.0	40.2	14.4	14.0	7.3	9.3	10.9	12.2	12.4	9.1	13.9	33.6	4.9	33.5	30.3	24.0	27.6	20.8	16.4	14.8	9.2	17.7	16.4	17.6	17.5	8.3	8.4	11.2	17.8	8.1	16.9	52.7	7.3	11.0	14.1	13.6	8.8	11.6	7.5	19.3	70.7	11.1	8.8	15.7	40.6	16.6	56.5	14.1	7.7	7.4	5.7	26.0	10.8	16.6	2.4	2.8	1.6	1.6	3.7	2.2	3.6	1.9	1.4	1.4	3.2	2.1	1.9	6.0	2.8	1.4	1.4	2.9	1.8	19.0	25.9	27.3	31.6	31.9	14.0	21.3	15.2	22.0	14.0	19.3	28.3	8.4	25.6	12.6	17.0	9.2	18.4	12.7	5.7	2.8	20.7	13.2	6.5	23.7	14.3	6.2	7.3	79.2	10.9	5.3	25.0	1.9	12.3	14.5	16.8	11.3	12.5	25.7	81.7	31.3	8.3	7.4	20.6	9.7	15.2	1.3	10.3	27.8	24.1	16.6	47.1	23.7	11.0	16.2	21.6	19.2	20.4	28.0	13.2	10.6	18.7	12.2	13.3	6.2	17.1	32.4	9.8	15.6	20.3	4.4	11.6	36.8	6.1	9.1	18.5	19.7	24.8	11.1	6.3	10.8	5.3	18.2	33.8	10.0	16.3	12.6	13.0
HRAS	HRAS1	ENSG00000174775	"HRas proto-oncogene, GTPase"	P01112	11	532242-537287	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"		Hydrolase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Suprabasal keratinocytes: 145.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"non-classical monocyte: 4.0"	"Low lineage specificity"	"Detected in many"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002015, HPA049830, HPA070222"	Approved		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 27: Non-specific - Gene expression"	"Cluster 27: Brain & Skin - Unknown function"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 22: Epithelial cell types - Mixed function"	"Nucleoplasm, Cytosol"		"CAB002015: , HPA049830: AB_2680903, HPA070222: "	"unprognostic (3.06e-2)"	"unprognostic (2.98e-2)"	"unprognostic (7.01e-2)"	"unprognostic (3.08e-3)"	"unprognostic (3.49e-3)"	"unprognostic (3.87e-1)"	"prognostic unfavorable (2.32e-4)"	"unprognostic (1.07e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.88e-3)"	"unprognostic (9.85e-2)"	"unprognostic (2.81e-1)"	"unprognostic (1.85e-1)"	"unprognostic (1.80e-1)"	"unprognostic (1.58e-2)"	"unprognostic (1.38e-1)"	28.1	24.6	64.6	3.5	67.2	2.9	27.0	62.1	86.8	30.4	58.3	34.3	2.8	23.6	12.5	80.1	18.9	3.6	56.8	64.4	64.6	33.8	21.8	27.1	4.3	65.6	65.3	20.0	20.5	13.1	38.2	9.0	66.9	38.3	6.9	10.2	27.3	12.3	59.0	69.9	19.5	8.9	64.2	20.6	24.2	16.5	64.8	9.2	20.5	25.2	10.2	34.5	44.2	65.4	59.0	105.6	44.2	25.6	22.2	17.5	39.6	49.9	25.1	64.5	29.5	62.4	29.7	20.4	10.9	63.2	60.7	43.7	46.0	114.1	19.3	19.5	108.4	6.6	43.7	56.1	38.5	13.9	12.0	28.3	118.0	42.0	51.5	19.6	31.5	34.3	29.7	32.3	40.9	110.6	34.0	50.5	26.5	39.9	94.5	31.6	40.7	18.2	47.0	33.2	87.6	43.7	25.5	55.4	17.9	31.5	43.3	14.8	35.4	47.3	44.7	16.4	39.7	20.3	17.7	15.4	39.1	17.0	38.3	0.0	0.5	0.6	0.8	0.7	0.4	0.3	0.9	0.8	0.7	2.0	0.9	0.3	0.0	0.1	4.0	0.9	1.5	0.2	64.6	67.2	62.1	86.8	64.4	64.6	65.6	65.3	66.9	64.2	64.8	65.4	51.3	12.8	10.7	9.1	18.0	131.2	101.7	25.4	82.0	46.0	38.8	75.7	25.2	22.8	11.2	35.0	18.8	78.8	21.5	72.2	74.3	35.2	1.6	36.1	28.6	32.0	29.3	11.2	9.8	37.4	63.4	25.9	33.6	34.1	2.5	26.8	22.9	17.4	39.9	48.8	10.6	26.5	4.1	11.7	38.4	7.9	17.1	21.3	64.0	10.3	12.8	50.8	11.3	4.0	12.3	48.2	30.9	23.0	26.5	61.2	30.8	54.6	20.0	37.6	32.9	20.3	40.3	5.4	21.4	118.1	145.9	78.1	22.0	18.8	26.2	106.4
MET	"DFNB97, HGFR, RCCP2"	ENSG00000105976	"MET proto-oncogene, receptor tyrosine kinase"	P08581	7	116672196-116798377	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"liver: 42.9"	"Cell type enhanced"	"Detected in many"		"Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6"	"Low cancer specificity"	"Detected in all"			"Group enriched"	"Detected in many"	5	"cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in many"		"A-431: 203.8;CAPAN-2: 219.0"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB005282, CAB018577, HPA055607"	Approved		Approved	"Plasma membrane,Cytosol"	"Secreted to blood"	NA	NA	179000000	100000000		"Cluster 86: Liver & Placenta - Transport via ER"	"Cluster 42: Epithelial cell lines - Epithelial cell function"	"Cluster 44: Endometrium - Transcription"	"Plasma membrane, Cytosol"		"CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860"	"unprognostic (1.60e-2)"	"unprognostic (7.71e-2)"	"unprognostic (2.53e-2)"	"unprognostic (1.58e-1)"	"unprognostic (3.57e-3)"	"prognostic unfavorable (6.75e-4)"	"unprognostic (1.68e-1)"	"unprognostic (3.22e-2)"	"unprognostic (3.81e-2)"	"unprognostic (2.52e-2)"	"prognostic unfavorable (1.21e-7)"	"unprognostic (1.86e-1)"	"unprognostic (1.25e-1)"	"unprognostic (5.53e-2)"	"unprognostic (8.88e-2)"	"unprognostic (2.01e-2)"	"unprognostic (2.20e-1)"	10.3	0.8	0.1	3.4	0.6	7.4	8.9	0.1	7.5	13.1	9.6	9.7	6.5	6.4	2.5	6.1	4.7	11.9	6.2	6.6	0.8	20.1	42.9	20.3	2.3	1.1	2.5	0.8	6.6	0.8	3.8	26.4	4.9	6.7	9.3	3.9	8.7	11.2	14.3	7.7	8.2	5.7	0.3	6.0	15.4	0.5	0.5	3.7	17.6	11.0	3.2	18.4	4.4	7.8	203.8	115.3	0.1	0.6	8.6	8.7	7.9	113.7	48.2	60.3	51.1	25.0	219.0	8.4	179.0	72.1	163.3	51.8	19.7	110.0	123.7	0.3	23.4	0.1	112.5	21.4	1.5	0.3	0.2	11.4	42.4	40.6	129.1	109.4	42.4	0.2	4.5	0.8	114.1	5.0	0.1	0.1	17.3	32.9	113.0	0.2	95.3	0.2	105.8	24.0	16.5	0.0	45.4	15.4	44.9	19.8	0.4	0.9	72.3	89.7	30.6	46.7	88.9	2.5	19.1	1.5	99.3	0.3	12.9	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.1	0.6	0.1	7.5	6.6	0.8	1.1	2.5	4.9	0.3	0.5	7.8	32.6	28.9	103.6	0.3	1.0	39.0	70.5	58.1	38.1	6.7	6.5	6.9	12.3	11.5	99.8	31.3	0.0	76.0	0.4	20.5	0.0	38.5	0.0	52.5	11.6	20.1	7.2	0.0	2.6	46.9	7.5	7.4	32.6	161.4	0.0	0.0	3.9	30.5	7.0	0.0	1.0	20.5	18.3	1.3	2.2	0.1	0.6	4.4	3.6	1.9	1.0	7.6	0.0	0.5	7.7	93.9	5.5	0.0	0.4	149.3	11.2	15.6	34.5	0.3	0.0	37.8	5.2	0.0	0.6	7.9	17.8	21.8	1.2	0.0	16.4	128.6
RASSF1	"123F2, NORE2A, RDA32, REH3P21"	ENSG00000068028	"Ras association domain family member 1"	Q9NS23	3	50329782-50340980	"Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins"	"Cell cycle"		"Tumor suppressor"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"dendritic cells: 116.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 252.6"	"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA040735	Approved					NA	Yes			"Cluster 46: Basophils - DNA binding"	"Cluster 82: Adipose tissue - ECM organization"	"Cluster 24: NB-4 - Immune response"	"Cluster 63: NK-cells & T-cells - Immune response"			"HPA040735: AB_10671692"	"unprognostic (5.02e-2)"	"prognostic favorable (2.64e-4)"	"unprognostic (3.05e-1)"	"unprognostic (2.95e-2)"	"unprognostic (1.00e-3)"	"prognostic favorable (2.60e-4)"	"prognostic unfavorable (9.77e-4)"	"unprognostic (3.80e-2)"	"unprognostic (2.11e-1)"	"unprognostic (1.07e-2)"	"unprognostic (1.54e-1)"	"unprognostic (3.47e-2)"	"prognostic unfavorable (8.58e-5)"	"unprognostic (4.27e-2)"	"unprognostic (2.29e-1)"	"unprognostic (1.11e-1)"	"unprognostic (9.71e-2)"	50.1	18.9	19.2	23.2	19.5	84.3	46.0	19.6	20.1	44.1	18.1	28.4	15.6	29.7	11.1	26.2	35.4	21.5	47.7	18.4	19.2	39.0	24.7	61.2	39.5	20.8	20.0	31.2	35.3	7.5	22.2	25.8	20.4	31.6	11.6	6.1	30.2	11.8	28.5	38.9	39.6	18.1	20.7	72.3	31.7	38.5	20.4	16.3	29.7	14.3	25.5	32.3	37.4	22.1	37.4	15.1	11.1	18.5	25.0	33.8	16.2	62.5	40.9	52.6	41.8	34.7	27.3	18.0	9.4	67.3	23.6	19.6	23.3	26.1	28.3	44.6	15.2	61.8	51.9	18.4	28.6	61.2	65.2	26.1	18.1	52.0	18.4	15.4	23.7	21.8	26.2	40.7	24.1	13.1	23.3	81.9	14.7	31.2	44.9	19.0	11.4	41.4	15.7	10.8	13.0	23.9	55.6	37.2	41.5	11.2	22.3	59.2	22.9	36.1	27.2	52.0	31.3	16.5	11.7	39.4	20.3	75.6	66.1	252.6	23.3	79.5	77.0	41.5	48.3	44.3	24.6	55.3	24.9	33.6	15.7	37.7	18.4	64.6	59.1	18.5	27.5	42.0	19.2	19.5	19.6	20.1	18.4	19.2	20.8	20.0	20.4	20.7	20.4	22.1	76.6	16.0	8.1	4.6	50.7	73.8	36.3	22.6	34.1	11.6	32.7	22.9	14.3	12.8	14.4	1.8	14.6	27.5	116.1	12.2	5.9	23.1	2.4	16.5	16.3	47.4	16.7	33.2	3.8	26.5	28.1	29.1	27.0	17.6	57.1	9.0	26.0	4.3	38.6	3.3	3.8	19.4	22.4	27.7	43.8	10.4	19.0	28.7	90.7	9.4	23.2	6.1	93.7	2.0	6.0	40.9	17.4	14.7	63.8	24.7	12.1	10.2	7.7	10.1	26.3	19.3	50.4	33.1	11.0	19.2	50.2	16.6	67.2	9.0	15.2	21.3
RB1	"OSRC, PPP1R130, RB"	ENSG00000139687	"RB transcriptional corepressor 1"	P06400	13	48303744-48599436	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Langerhans cells: 198.9"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in many"		"MOLT-4: 187.2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000095, CAB016687, HPA050082"	Supported		Supported	Nucleoplasm		NA	NA			"Cluster 23: Antigen presenting cells - Antigen presentation"	"Cluster 16: Immune cells - Immune response"	"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response"	"Cluster 41: Macrophages - Immune response"	Nucleoplasm		"CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008"	"unprognostic (4.24e-3)"	"unprognostic (1.00e-1)"	"unprognostic (3.62e-2)"	"unprognostic (4.67e-2)"	"unprognostic (2.04e-2)"	"unprognostic (3.86e-1)"	"unprognostic (4.69e-2)"	"unprognostic (7.08e-2)"	"unprognostic (1.59e-1)"	"prognostic unfavorable (6.92e-4)"	"unprognostic (4.06e-2)"	"unprognostic (9.40e-2)"	"unprognostic (4.67e-2)"	"unprognostic (1.79e-1)"	"unprognostic (9.99e-2)"	"unprognostic (2.31e-1)"	"unprognostic (1.70e-1)"	20.7	18.7	8.9	22.8	9.7	19.3	17.8	12.0	13.0	18.8	10.9	15.1	14.6	15.7	21.2	21.9	13.1	17.3	17.8	8.5	10.9	18.4	14.5	18.1	30.7	13.9	10.3	11.5	9.2	20.5	6.5	24.9	13.4	15.1	17.1	12.5	16.9	15.9	19.0	23.6	15.6	18.3	11.6	24.8	16.3	12.9	9.3	34.2	22.4	21.2	30.1	19.8	10.6	15.1	29.1	15.8	40.9	44.2	19.8	22.8	18.5	56.6	45.9	57.4	48.3	13.4	49.8	37.3	12.8	37.4	31.7	39.6	53.7	44.8	86.6	53.0	20.8	68.5	29.4	22.7	21.1	59.5	62.0	12.9	27.0	37.3	47.1	47.8	40.1	90.1	23.4	29.6	66.4	13.7	187.2	29.8	20.0	65.6	17.3	79.8	41.1	43.0	59.6	27.6	2.0	41.8	55.1	27.3	46.2	36.2	29.8	76.3	32.1	35.3	23.3	43.7	51.2	13.1	3.9	0.4	18.8	36.7	48.9	23.8	14.9	8.8	6.9	19.9	5.6	30.2	5.7	6.9	15.2	29.4	4.8	5.6	20.6	5.9	20.9	16.9	7.4	7.1	8.9	9.7	12.0	13.0	8.5	10.9	13.9	10.3	13.4	11.6	9.3	15.1	59.2	3.2	19.6	75.4	97.3	28.4	23.3	27.6	63.2	17.3	26.9	21.0	18.3	14.3	19.2	31.3	29.2	7.1	50.1	17.8	15.6	19.3	28.1	40.1	36.2	46.4	17.5	50.7	99.5	11.9	9.6	22.2	29.0	40.4	12.0	25.9	35.7	17.3	77.4	18.5	98.9	20.0	8.2	105.3	198.9	13.9	26.1	104.2	26.6	152.7	93.7	20.4	22.6	101.0	98.3	17.4	10.7	28.6	69.9	24.0	15.7	23.6	25.3	19.6	19.7	28.5	32.3	33.0	21.3	72.1	38.2	4.4	38.3	21.2	16.6	18.0
TFE3	"bHLHe33, TFEA"	ENSG00000068323	"Transcription factor binding to IGHM enhancer 3"	P19532	X	49028726-49043410	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Adaptive immunity, Immunity, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 12.5"	"Group enriched"	"Detected in many"	4	"granulocytes: 12.5;monocytes: 6.3"	"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA023881	Approved		Approved	Nucleoplasm,Cytosol		NA	NA			"Cluster 8: Neutrophils - Inflammatory response"	"Cluster 57: Non-specific - Angiogenesis"	"Cluster 30: Epithelial cell lines - Translation"	"Cluster 41: Macrophages - Immune response"	"Nucleoplasm, Cytosol"		"HPA023881: AB_1857931"	"unprognostic (2.68e-2)"	"unprognostic (2.89e-3)"	"unprognostic (2.40e-2)"	"unprognostic (5.36e-2)"	"unprognostic (2.71e-2)"	"unprognostic (1.81e-1)"	"prognostic unfavorable (6.03e-5)"	"unprognostic (2.40e-1)"	"unprognostic (1.26e-1)"	"unprognostic (4.32e-2)"	"unprognostic (5.41e-2)"	"unprognostic (1.16e-1)"	"prognostic unfavorable (2.19e-8)"	"unprognostic (1.93e-1)"	"unprognostic (8.77e-2)"	"unprognostic (4.19e-2)"	"unprognostic (6.25e-1)"	31.3	23.6	27.8	16.8	27.3	24.1	22.9	25.8	26.9	24.1	23.3	23.6	10.8	24.7	21.1	15.6	26.2	18.5	17.2	25.7	29.4	15.1	12.6	29.2	11.8	37.2	30.9	25.8	12.4	25.1	18.4	20.8	28.7	17.2	11.5	14.8	13.4	28.3	17.0	20.5	14.7	24.7	27.5	22.5	16.8	5.9	32.2	10.7	20.0	14.0	13.2	25.0	20.5	25.6	32.8	41.5	14.6	44.6	48.6	45.1	12.5	40.6	55.8	49.7	38.2	23.3	26.8	10.2	18.0	65.7	48.6	25.5	25.4	40.2	44.8	24.4	11.8	8.3	39.6	26.2	69.0	10.0	28.3	38.5	32.3	64.4	50.1	47.8	26.3	8.4	19.8	55.9	49.2	20.6	7.5	17.2	36.3	11.0	34.1	11.9	22.2	26.6	43.1	18.0	12.4	12.4	44.8	19.0	17.9	52.5	27.6	15.0	48.5	47.1	48.7	48.0	27.3	30.1	29.7	8.0	56.1	14.0	33.2	0.0	4.8	1.8	0.6	4.7	1.1	0.5	0.9	0.5	2.2	1.0	0.6	0.5	12.5	0.4	6.3	0.5	1.3	2.6	27.8	27.3	25.8	26.9	25.7	29.4	37.2	30.9	28.7	27.5	32.2	25.6	13.8	16.0	8.8	13.7	9.8	19.8	19.7	11.2	30.1	6.8	10.9	9.4	8.1	15.7	11.8	20.2	4.2	16.0	4.4	14.3	9.8	17.7	0.7	10.9	15.3	17.5	12.5	5.2	7.5	15.8	9.4	20.2	14.3	14.8	5.7	12.0	10.8	15.0	22.3	18.5	7.2	8.2	0.0	21.7	29.4	2.2	27.4	20.5	8.8	11.2	15.5	12.0	4.1	6.0	7.7	21.4	13.7	24.5	12.9	20.2	10.6	12.1	7.0	5.6	13.1	18.5	14.3	2.2	0.8	18.9	22.0	37.1	8.6	13.9	7.5	19.6
TP53	"LFS1, p53"	ENSG00000141510	"Tumor protein p53"	P04637	17	7661779-7687538	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters"	"Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation"	"Activator, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cell line specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876, CAB079965"	Enhanced		Supported	Nucleoplasm,Mitochondria,Cytosol		Yes	No			"Cluster 39: Non-specific - mRNA processing"	"Cluster 3: T-cells - Adaptive immune response"	"Cluster 14: REH - Unknown function"	"Cluster 32: Non-specific - Translation"	Nucleoplasm	"Mitochondria, Cytosol"	"CAB002973: AB_2206626, CAB039238: , CAB039239: , CAB072876: AB_2665731, CAB079965: , HPA051244: AB_2681403, HPA063532: "	"unprognostic (2.29e-2)"	"unprognostic (8.83e-3)"	"unprognostic (1.26e-2)"	"prognostic favorable (1.35e-4)"	"unprognostic (9.95e-2)"	"unprognostic (4.00e-2)"	"unprognostic (2.79e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.75e-2)"	"unprognostic (2.55e-1)"	"unprognostic (1.30e-1)"	"prognostic unfavorable (5.01e-4)"	"unprognostic (1.86e-3)"	"unprognostic (7.89e-3)"	"unprognostic (8.05e-2)"	"unprognostic (2.74e-1)"	"unprognostic (1.08e-1)"	19.3	13.8	10.4	27.1	12.6	19.6	22.5	10.4	16.5	19.9	10.3	29.0	18.9	24.5	12.8	28.8	31.3	13.2	11.1	10.1	11.4	14.9	16.5	15.1	34.6	18.7	13.6	27.3	18.3	9.4	7.3	23.5	12.5	17.7	27.5	4.1	18.9	15.3	12.3	37.4	20.4	24.6	12.6	31.1	22.6	10.4	12.3	47.2	17.4	6.1	45.4	20.8	19.9	13.3	81.5	145.3	81.1	57.3	37.3	43.9	82.8	28.4	66.1	78.5	100.2	4.2	40.6	190.5	126.9	58.7	77.6	174.9	119.7	80.4	72.8	42.7	76.5	77.6	76.8	70.9	111.5	1.6	37.0	55.7	93.0	38.9	106.5	45.6	79.4	24.7	3.8	6.9	41.5	145.1	130.0	96.3	80.2	10.4	2.4	252.2	56.1	66.2	59.4	87.3	46.0	80.5	94.1	62.6	24.3	39.4	109.2	7.4	100.7	91.6	30.2	1.0	48.3	47.6	37.9	82.5	23.6	9.7	80.1	1.2	21.2	3.4	13.0	21.7	15.9	21.5	13.3	14.6	30.3	19.1	13.7	15.4	2.4	17.5	19.3	27.3	17.3	14.7	10.4	12.6	10.4	16.5	10.1	11.4	18.7	13.6	12.5	12.6	12.3	13.3	21.1	9.6	12.8	16.3	26.0	28.7	14.5	24.6	24.5	2.6	36.1	30.4	2.5	18.6	15.4	20.2	0.0	36.9	24.7	16.9	9.8	24.8	12.8	11.5	29.0	24.5	30.7	21.7	2.1	18.1	39.6	17.0	11.2	19.5	1.3	31.7	22.1	18.0	24.2	0.0	3.2	43.0	18.3	27.8	20.1	3.8	23.0	19.3	12.4	7.5	31.9	4.9	25.7	9.0	8.0	15.8	16.4	17.0	7.8	15.7	10.3	10.1	8.8	2.6	13.1	25.9	20.6	0.5	4.9	28.7	32.8	22.4	16.5	27.4	54.1	11.5
VHL	VHL1	ENSG00000134086	"Von Hippel-Lindau tumor suppressor"	P40337	3	10141778-10153667	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Ubl conjugation pathway"		"Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Cell line enhanced"	"Detected in all"		"BEWO: 146.5"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA031631, HPA031632, HPA068954"	Approved		Enhanced	Nucleoplasm,Cytosol		NA	NA			"Cluster 17: Basophils - Unknown function"	"Cluster 66: Lymphoid tissue - Immune response regulation"	"Cluster 28: BEWO - Transcription regulation"	"Cluster 57: B-cells - Immune response"	Nucleoplasm	Cytosol	"HPA031631: AB_2673968, HPA031632: AB_2673969, HPA068954: "	"prognostic unfavorable (9.02e-5)"	"unprognostic (1.10e-1)"	"unprognostic (4.46e-3)"	"unprognostic (1.52e-1)"	"unprognostic (1.10e-1)"	"unprognostic (1.33e-1)"	"prognostic unfavorable (1.32e-5)"	"unprognostic (3.55e-1)"	"unprognostic (3.03e-2)"	"unprognostic (4.36e-2)"	"unprognostic (5.82e-3)"	"unprognostic (1.81e-2)"	"unprognostic (2.51e-1)"	"prognostic favorable (7.84e-4)"	"unprognostic (1.46e-1)"	"unprognostic (2.92e-2)"	"unprognostic (1.28e-3)"	14.0	13.7	11.5	21.1	11.0	27.9	14.7	13.6	12.1	11.8	6.7	14.8	15.7	14.1	9.8	12.3	13.4	11.5	7.9	11.8	14.9	12.6	14.1	11.8	29.6	9.4	9.4	12.6	12.7	11.7	9.0	14.1	9.3	14.0	15.7	8.9	14.5	10.2	11.4	14.2	17.2	12.8	9.6	22.5	16.0	13.4	16.6	23.4	15.8	7.7	29.7	12.5	10.9	12.5	19.5	18.2	39.9	24.6	36.0	27.7	146.5	16.8	24.0	21.1	24.5	21.5	23.7	67.9	22.2	23.0	29.9	16.4	37.2	23.6	25.7	33.0	33.7	52.7	30.5	30.6	34.3	47.3	41.3	28.1	26.3	28.0	35.1	28.4	24.6	42.5	48.3	50.3	21.1	35.0	45.5	40.9	26.7	21.1	23.4	57.3	34.6	34.6	25.5	48.7	15.0	49.4	35.0	18.7	21.0	23.9	37.0	59.1	21.3	20.8	27.7	19.6	26.8	35.7	78.1	105.6	23.2	55.3	19.4	4.6	3.2	2.3	2.6	2.2	1.9	2.5	1.8	2.2	2.0	3.3	1.7	1.8	5.6	3.0	2.0	2.3	1.7	1.2	11.5	11.0	13.6	12.1	11.8	14.9	9.4	9.4	9.3	9.6	16.6	12.5	12.4	12.8	12.5	9.1	38.7	14.7	17.8	14.3	24.5	14.7	10.7	6.1	6.1	20.0	9.6	16.5	18.8	16.8	21.9	10.7	7.9	11.8	9.6	13.1	26.1	14.8	14.4	30.5	15.9	5.1	18.7	12.8	20.9	19.9	5.1	18.4	18.9	14.3	14.9	18.5	14.2	11.3	16.2	27.1	45.8	7.3	14.0	32.3	12.4	7.5	31.9	9.1	28.8	12.1	14.9	10.7	11.7	11.3	33.3	23.8	12.3	9.5	9.7	15.3	6.6	17.4	11.9	15.4	24.0	26.7	20.5	17.2	23.5	21.4	10.2	25.9
WT1	"AWT1, GUD, NPHS4, WAGR, WIT-2"	ENSG00000184937	"WT1 transcription factor"	P19544	11	32387775-32435564	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, RNA-binding"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"endometrium 1: 67.6;fallopian tube: 52.3;ovary: 45.8"	"Cell type enhanced"	"Detected in some"		"Collecting duct cells: 20.2;Endometrial stromal cells: 70.1;Endothelial cells: 16.3;Granulosa cells: 9.3;Late spermatids: 9.3"	"Cancer enriched"	"Detected in many"	14	"ovarian cancer: 55.2"	"Not detected"	"Not detected"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cell line enhanced"	"Detected in some"		"HEL: 20.7;HMC-1: 29.9;K-562: 19.6;NB-4: 37.2;THP-1: 19.6"	"Not detected"	"Not detected"			"Not detected"	"Not detected"			"CAB000327, HPA035717, HPA053848"	Enhanced		Enhanced	Nucleoplasm		NA	NA				"Cluster 89: Fibroblasts - ECM organization"	"Cluster 1: K-562 - Erythropoiesis"	"Cluster 36: Stromal cells - Cell proliferation"	Nucleoplasm		"CAB000327: AB_2304486, HPA035717: AB_2674748, HPA053848: AB_2682279"	"unprognostic (3.09e-3)"	"unprognostic (9.97e-4)"	"unprognostic (3.32e-1)"	"unprognostic (8.24e-3)"	"unprognostic (5.20e-2)"	"unprognostic (1.98e-3)"	"unprognostic (2.94e-2)"	"unprognostic (1.59e-2)"	"unprognostic (1.23e-2)"	"unprognostic (4.15e-2)"	"unprognostic (1.86e-2)"	"unprognostic (1.36e-1)"	"unprognostic (1.31e-10)"	"unprognostic (2.65e-3)"	"unprognostic (1.87e-1)"	"unprognostic (1.96e-3)"	"unprognostic (1.30e-2)"	26.5	0.2	0.0	0.5	0.1	0.0	0.1	0.0	0.1	18.4	0.0	0.7	0.0	67.6	5.3	0.0	52.3	1.3	4.5	0.1	0.0	16.3	0.1	0.8	0.0	0.2	0.1	45.8	0.1	0.0	0.0	1.3	0.0	0.7	0.0	0.0	0.0	2.9	0.0	0.0	0.1	33.1	0.0	19.0	0.2	24.2	0.0	0.0	0.0	0.0	0.0	0.2	8.4	0.0	0.0	3.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	6.9	0.0	0.0	0.1	0.0	0.0	0.0	8.1	0.0	0.0	0.0	8.4	20.7	0.0	1.2	4.7	10.8	29.9	0.0	0.0	3.4	0.0	0.0	0.0	0.7	19.6	0.0	2.0	0.0	11.2	37.2	0.8	0.0	6.3	1.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	2.9	2.1	19.6	0.2	0.0	3.3	0.0	0.3	0.0	0.0	0.0	0.0	0.9	0.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.1	0.1	0.0	0.2	0.1	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	1.6	0.0	0.0	20.2	0.0	1.0	0.0	0.0	0.0	0.0	3.6	2.2	70.1	16.3	0.0	0.0	0.1	0.0	0.5	7.3	0.0	1.4	0.0	9.3	1.4	0.0	0.3	0.0	0.1	0.0	0.0	0.0	0.0	9.3	8.4	0.7	0.0	0.0	0.0	0.0	0.0	0.0	0.1	0.0	0.0	1.2	0.0	0.1	0.0	2.3	0.0	0.0	6.6	0.0	2.0	4.5	1.0	0.0	0.0	0.8	0.5	0.4	0.0	0.1