[{"Gene":"ABL1","Gene synonym":["ABL","c-ABL","JTK7","p150"],"Ensembl":"ENSG00000097007","Gene description":"ABL proto-oncogene 1, non-receptor tyrosine kinase","Uniprot":["P00519"],"Chromosome":"9","Position":"130713016-130887675","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Apoptosis","Autophagy","Cell adhesion","DNA damage","DNA repair","Endocytosis"],"Molecular function":["DNA-binding","Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"71.2","Oligodendrocytes":"116.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002686","HPA027251","HPA027280","HPA028409"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB002686":null,"HPA027251":"AB_1844453","HPA027280":"AB_1844454","HPA028409":"AB_10601011"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.55e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"50.9","Tissue RNA - adrenal gland [nTPM]":"30.7","Tissue RNA - amygdala [nTPM]":"27.4","Tissue RNA - appendix [nTPM]":"25.3","Tissue RNA - basal ganglia [nTPM]":"38.9","Tissue RNA - bone marrow [nTPM]":"23.4","Tissue RNA - breast [nTPM]":"45.8","Tissue RNA - cerebellum [nTPM]":"33.6","Tissue RNA - cerebral cortex [nTPM]":"31.4","Tissue RNA - cervix [nTPM]":"60.5","Tissue RNA - choroid plexus [nTPM]":"40.4","Tissue RNA - colon [nTPM]":"96.4","Tissue RNA - duodenum [nTPM]":"23.1","Tissue RNA - endometrium 1 [nTPM]":"63.0","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"33.8","Tissue RNA - fallopian tube [nTPM]":"55.6","Tissue RNA - gallbladder [nTPM]":"35.7","Tissue RNA - heart muscle [nTPM]":"36.1","Tissue RNA - hippocampal formation [nTPM]":"26.6","Tissue RNA - hypothalamus [nTPM]":"28.3","Tissue RNA - kidney [nTPM]":"23.1","Tissue RNA - liver [nTPM]":"17.5","Tissue RNA - lung [nTPM]":"37.3","Tissue RNA - lymph node [nTPM]":"16.3","Tissue RNA - medulla oblongata [nTPM]":"39.3","Tissue RNA - midbrain [nTPM]":"38.5","Tissue RNA - ovary [nTPM]":"56.0","Tissue RNA - pancreas [nTPM]":"24.9","Tissue RNA - parathyroid gland [nTPM]":"32.5","Tissue RNA - pituitary gland [nTPM]":"34.9","Tissue RNA - placenta [nTPM]":"26.5","Tissue RNA - pons [nTPM]":"35.8","Tissue RNA - prostate [nTPM]":"43.5","Tissue RNA - rectum [nTPM]":"26.7","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"32.4","Tissue RNA - seminal vesicle [nTPM]":"33.6","Tissue RNA - skeletal muscle [nTPM]":"29.4","Tissue RNA - skin 1 [nTPM]":"36.3","Tissue RNA - small intestine [nTPM]":"45.2","Tissue RNA - smooth muscle [nTPM]":"41.2","Tissue RNA - spinal cord [nTPM]":"31.3","Tissue RNA - spleen [nTPM]":"23.3","Tissue RNA - stomach 1 [nTPM]":"51.6","Tissue RNA - testis [nTPM]":"20.1","Tissue RNA - thalamus [nTPM]":"34.9","Tissue RNA - thymus [nTPM]":"22.4","Tissue RNA - thyroid gland [nTPM]":"46.7","Tissue RNA - tongue [nTPM]":"30.8","Tissue RNA - tonsil [nTPM]":"15.4","Tissue RNA - urinary bladder [nTPM]":"79.3","Tissue RNA - vagina [nTPM]":"42.7","Tissue RNA - white matter [nTPM]":"41.3","Cell RNA - A-431 [nTPM]":"22.5","Cell RNA - A549 [nTPM]":"48.3","Cell RNA - AF22 [nTPM]":"53.6","Cell RNA - AN3-CA [nTPM]":"62.9","Cell RNA - ASC diff [nTPM]":"76.5","Cell RNA - ASC TERT1 [nTPM]":"93.3","Cell RNA - BEWO [nTPM]":"18.8","Cell RNA - BJ [nTPM]":"38.8","Cell RNA - BJ hTERT+ [nTPM]":"60.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.1","Cell RNA - CACO-2 [nTPM]":"36.4","Cell RNA - CAPAN-2 [nTPM]":"28.3","Cell RNA - Daudi [nTPM]":"32.3","Cell RNA - EFO-21 [nTPM]":"22.3","Cell RNA - fHDF\/TERT166 [nTPM]":"52.0","Cell RNA - GAMG [nTPM]":"47.6","Cell RNA - HaCaT [nTPM]":"42.5","Cell RNA - HAP1 [nTPM]":"23.5","Cell RNA - HBEC3-KT [nTPM]":"36.0","Cell RNA - HBF TERT88 [nTPM]":"30.7","Cell RNA - HDLM-2 [nTPM]":"20.6","Cell RNA - HEK 293 [nTPM]":"16.3","Cell RNA - HEL [nTPM]":"23.7","Cell RNA - HeLa [nTPM]":"84.1","Cell RNA - Hep G2 [nTPM]":"33.4","Cell RNA - HHSteC [nTPM]":"51.8","Cell RNA - HL-60 [nTPM]":"36.5","Cell RNA - HMC-1 [nTPM]":"32.3","Cell RNA - HSkMC [nTPM]":"68.8","Cell RNA - hTCEpi [nTPM]":"37.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"80.6","Cell RNA - hTERT-HME1 [nTPM]":"50.0","Cell RNA - hTERT-RPE1 [nTPM]":"64.1","Cell RNA - HUVEC TERT2 [nTPM]":"61.0","Cell RNA - JURKAT [nTPM]":"47.9","Cell RNA - K-562 [nTPM]":"135.8","Cell RNA - Karpas-707 [nTPM]":"26.5","Cell RNA - LHCN-M2 [nTPM]":"54.9","Cell RNA - MCF7 [nTPM]":"42.0","Cell RNA - MOLT-4 [nTPM]":"49.2","Cell RNA - NB-4 [nTPM]":"30.5","Cell RNA - NTERA-2 [nTPM]":"57.9","Cell RNA - OE19 [nTPM]":"34.3","Cell RNA - PC-3 [nTPM]":"33.8","Cell RNA - REH [nTPM]":"55.9","Cell RNA - RH-30 [nTPM]":"67.9","Cell RNA - RPMI-8226 [nTPM]":"35.9","Cell RNA - RPTEC TERT1 [nTPM]":"45.0","Cell RNA - RT4 [nTPM]":"25.7","Cell RNA - SCLC-21H [nTPM]":"47.9","Cell RNA - SH-SY5Y [nTPM]":"60.1","Cell RNA - SiHa [nTPM]":"66.1","Cell RNA - SK-BR-3 [nTPM]":"23.5","Cell RNA - SK-MEL-30 [nTPM]":"29.2","Cell RNA - SuSa [nTPM]":"31.0","Cell RNA - T-47d [nTPM]":"46.2","Cell RNA - THP-1 [nTPM]":"33.1","Cell RNA - TIME [nTPM]":"71.1","Cell RNA - U-138 MG [nTPM]":"170.7","Cell RNA - U-2 OS [nTPM]":"44.1","Cell RNA - U-2197 [nTPM]":"66.3","Cell RNA - U-251 MG [nTPM]":"62.6","Cell RNA - U-266\/70 [nTPM]":"8.4","Cell RNA - U-266\/84 [nTPM]":"20.3","Cell RNA - U-698 [nTPM]":"47.9","Cell RNA - U-87 MG [nTPM]":"72.1","Cell RNA - U-937 [nTPM]":"27.6","Cell RNA - WM-115 [nTPM]":"55.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"1.9","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"27.4","Brain RNA - basal ganglia [nTPM]":"38.9","Brain RNA - cerebellum [nTPM]":"33.6","Brain RNA - cerebral cortex [nTPM]":"31.4","Brain RNA - hippocampal formation [nTPM]":"26.6","Brain RNA - hypothalamus [nTPM]":"28.3","Brain RNA - medulla oblongata [nTPM]":"39.3","Brain RNA - midbrain [nTPM]":"38.5","Brain RNA - pons [nTPM]":"35.8","Brain RNA - spinal cord [nTPM]":"31.3","Brain RNA - thalamus [nTPM]":"34.9","Brain RNA - white matter [nTPM]":"41.3","Single Cell Type RNA - Adipocytes [nTPM]":"16.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.6","Single Cell Type RNA - Astrocytes [nTPM]":"54.9","Single Cell Type RNA - B-cells [nTPM]":"4.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Bipolar cells [nTPM]":"8.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"7.2","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.6","Single Cell Type RNA - dendritic cells [nTPM]":"12.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.4","Single Cell Type RNA - Early spermatids [nTPM]":"5.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.7","Single Cell Type RNA - Endothelial cells [nTPM]":"18.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"22.1","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"52.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.3","Single Cell Type RNA - Fibroblasts [nTPM]":"36.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.4","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.3","Single Cell Type RNA - Hepatocytes [nTPM]":"15.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.6","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"63.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"16.4","Single Cell Type RNA - Langerhans cells [nTPM]":"11.7","Single Cell Type RNA - Late spermatids [nTPM]":"8.8","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"71.2","Single Cell Type RNA - monocytes [nTPM]":"6.6","Single Cell Type RNA - Muller glia cells [nTPM]":"19.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"116.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.9","Single Cell Type RNA - Paneth cells [nTPM]":"18.3","Single Cell Type RNA - Peritubular cells [nTPM]":"25.6","Single Cell Type RNA - Plasma cells [nTPM]":"5.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.1","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.8","Single Cell Type RNA - Spermatocytes [nTPM]":"16.9","Single Cell Type RNA - Spermatogonia [nTPM]":"16.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"15.2","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"20.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"21.4","Single Cell Type RNA - Urothelial cells [nTPM]":"7.2"},{"Gene":"AFF1","Gene synonym":["AF-4","AF4","MLLT2","PBM1"],"Ensembl":"ENSG00000172493","Gene description":"AF4\/FMR2 family member 1","Uniprot":["P51825"],"Chromosome":"4","Position":"86935002-87141054","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"225.2","Microglial cells":"202.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA069947"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA069947":"AB_2686219"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.09e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"33.2","Tissue RNA - adrenal gland [nTPM]":"18.0","Tissue RNA - amygdala [nTPM]":"10.7","Tissue RNA - appendix [nTPM]":"18.1","Tissue RNA - basal ganglia [nTPM]":"11.8","Tissue RNA - bone marrow [nTPM]":"35.0","Tissue RNA - breast [nTPM]":"22.8","Tissue RNA - cerebellum [nTPM]":"8.1","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"24.8","Tissue RNA - choroid plexus [nTPM]":"51.4","Tissue RNA - colon [nTPM]":"25.9","Tissue RNA - duodenum [nTPM]":"18.2","Tissue RNA - endometrium 1 [nTPM]":"25.6","Tissue RNA - epididymis [nTPM]":"11.8","Tissue RNA - esophagus [nTPM]":"19.1","Tissue RNA - fallopian tube [nTPM]":"21.4","Tissue RNA - gallbladder [nTPM]":"19.6","Tissue RNA - heart muscle [nTPM]":"19.6","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"32.8","Tissue RNA - liver [nTPM]":"24.8","Tissue RNA - lung [nTPM]":"20.7","Tissue RNA - lymph node [nTPM]":"16.3","Tissue RNA - medulla oblongata [nTPM]":"16.3","Tissue RNA - midbrain [nTPM]":"9.8","Tissue RNA - ovary [nTPM]":"28.8","Tissue RNA - pancreas [nTPM]":"28.2","Tissue RNA - parathyroid gland [nTPM]":"31.8","Tissue RNA - pituitary gland [nTPM]":"12.5","Tissue RNA - placenta [nTPM]":"26.8","Tissue RNA - pons [nTPM]":"11.8","Tissue RNA - prostate [nTPM]":"18.2","Tissue RNA - rectum [nTPM]":"22.5","Tissue RNA - retina [nTPM]":"63.6","Tissue RNA - salivary gland [nTPM]":"24.0","Tissue RNA - seminal vesicle [nTPM]":"22.8","Tissue RNA - skeletal muscle [nTPM]":"55.6","Tissue RNA - skin 1 [nTPM]":"23.4","Tissue RNA - small intestine [nTPM]":"19.4","Tissue RNA - smooth muscle [nTPM]":"31.9","Tissue RNA - spinal cord [nTPM]":"9.1","Tissue RNA - spleen [nTPM]":"19.4","Tissue RNA - stomach 1 [nTPM]":"19.0","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"14.2","Tissue RNA - thymus [nTPM]":"22.8","Tissue RNA - thyroid gland [nTPM]":"54.9","Tissue RNA - tongue [nTPM]":"41.8","Tissue RNA - tonsil [nTPM]":"13.4","Tissue RNA - urinary bladder [nTPM]":"18.5","Tissue RNA - vagina [nTPM]":"19.0","Tissue RNA - white matter [nTPM]":"12.0","Cell RNA - A-431 [nTPM]":"15.3","Cell RNA - A549 [nTPM]":"13.5","Cell RNA - AF22 [nTPM]":"11.3","Cell RNA - AN3-CA [nTPM]":"12.0","Cell RNA - ASC diff [nTPM]":"18.3","Cell RNA - ASC TERT1 [nTPM]":"21.6","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"15.1","Cell RNA - BJ hTERT+ [nTPM]":"22.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.7","Cell RNA - CACO-2 [nTPM]":"14.7","Cell RNA - CAPAN-2 [nTPM]":"27.8","Cell RNA - Daudi [nTPM]":"17.3","Cell RNA - EFO-21 [nTPM]":"20.2","Cell RNA - fHDF\/TERT166 [nTPM]":"18.7","Cell RNA - GAMG [nTPM]":"14.4","Cell RNA - HaCaT [nTPM]":"6.8","Cell RNA - HAP1 [nTPM]":"18.0","Cell RNA - HBEC3-KT [nTPM]":"22.8","Cell RNA - HBF TERT88 [nTPM]":"15.7","Cell RNA - HDLM-2 [nTPM]":"29.8","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"36.0","Cell RNA - HeLa [nTPM]":"38.3","Cell RNA - Hep G2 [nTPM]":"12.3","Cell RNA - HHSteC [nTPM]":"14.1","Cell RNA - HL-60 [nTPM]":"35.0","Cell RNA - HMC-1 [nTPM]":"27.4","Cell RNA - HSkMC [nTPM]":"17.7","Cell RNA - hTCEpi [nTPM]":"16.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.4","Cell RNA - hTERT-HME1 [nTPM]":"17.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.4","Cell RNA - HUVEC TERT2 [nTPM]":"42.1","Cell RNA - JURKAT [nTPM]":"14.1","Cell RNA - K-562 [nTPM]":"22.5","Cell RNA - Karpas-707 [nTPM]":"47.5","Cell RNA - LHCN-M2 [nTPM]":"4.8","Cell RNA - MCF7 [nTPM]":"4.1","Cell RNA - MOLT-4 [nTPM]":"31.6","Cell RNA - NB-4 [nTPM]":"10.1","Cell RNA - NTERA-2 [nTPM]":"15.0","Cell RNA - OE19 [nTPM]":"25.6","Cell RNA - PC-3 [nTPM]":"4.8","Cell RNA - REH [nTPM]":"24.7","Cell RNA - RH-30 [nTPM]":"6.7","Cell RNA - RPMI-8226 [nTPM]":"22.2","Cell RNA - RPTEC TERT1 [nTPM]":"33.1","Cell RNA - RT4 [nTPM]":"14.5","Cell RNA - SCLC-21H [nTPM]":"25.6","Cell RNA - SH-SY5Y [nTPM]":"4.7","Cell RNA - SiHa [nTPM]":"23.1","Cell RNA - SK-BR-3 [nTPM]":"15.0","Cell RNA - SK-MEL-30 [nTPM]":"7.2","Cell RNA - SuSa [nTPM]":"23.5","Cell RNA - T-47d [nTPM]":"9.0","Cell RNA - THP-1 [nTPM]":"28.9","Cell RNA - TIME [nTPM]":"21.3","Cell RNA - U-138 MG [nTPM]":"20.9","Cell RNA - U-2 OS [nTPM]":"18.8","Cell RNA - U-2197 [nTPM]":"12.9","Cell RNA - U-251 MG [nTPM]":"8.5","Cell RNA - U-266\/70 [nTPM]":"41.0","Cell RNA - U-266\/84 [nTPM]":"24.8","Cell RNA - U-698 [nTPM]":"29.6","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"39.5","Cell RNA - WM-115 [nTPM]":"7.7","Blood RNA - basophil [nTPM]":"5.4","Blood RNA - classical monocyte [nTPM]":"7.4","Blood RNA - eosinophil [nTPM]":"17.6","Blood RNA - gdT-cell [nTPM]":"8.8","Blood RNA - intermediate monocyte [nTPM]":"5.4","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"12.0","Blood RNA - memory CD4 T-cell [nTPM]":"11.8","Blood RNA - memory CD8 T-cell [nTPM]":"8.9","Blood RNA - myeloid DC [nTPM]":"8.5","Blood RNA - naive B-cell [nTPM]":"14.5","Blood RNA - naive CD4 T-cell [nTPM]":"6.0","Blood RNA - naive CD8 T-cell [nTPM]":"5.8","Blood RNA - neutrophil [nTPM]":"28.4","Blood RNA - NK-cell [nTPM]":"7.7","Blood RNA - non-classical monocyte [nTPM]":"3.3","Blood RNA - plasmacytoid DC [nTPM]":"20.7","Blood RNA - T-reg [nTPM]":"11.3","Blood RNA - total PBMC [nTPM]":"4.2","Brain RNA - amygdala [nTPM]":"10.7","Brain RNA - basal ganglia [nTPM]":"11.8","Brain RNA - cerebellum [nTPM]":"8.1","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"16.3","Brain RNA - midbrain [nTPM]":"9.8","Brain RNA - pons [nTPM]":"11.8","Brain RNA - spinal cord [nTPM]":"9.1","Brain RNA - thalamus [nTPM]":"14.2","Brain RNA - white matter [nTPM]":"12.0","Single Cell Type RNA - Adipocytes [nTPM]":"88.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"55.6","Single Cell Type RNA - Astrocytes [nTPM]":"125.7","Single Cell Type RNA - B-cells [nTPM]":"29.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"33.6","Single Cell Type RNA - Bipolar cells [nTPM]":"41.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"119.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"28.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"92.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"225.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"29.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.9","Single Cell Type RNA - Early spermatids [nTPM]":"7.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"32.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.1","Single Cell Type RNA - Endothelial cells [nTPM]":"50.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"32.3","Single Cell Type RNA - Erythroid cells [nTPM]":"54.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"69.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.2","Single Cell Type RNA - Fibroblasts [nTPM]":"36.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.2","Single Cell Type RNA - granulocytes [nTPM]":"25.2","Single Cell Type RNA - Granulosa cells [nTPM]":"40.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"65.0","Single Cell Type RNA - Hepatocytes [nTPM]":"34.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.0","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"47.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.8","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"41.7","Single Cell Type RNA - Langerhans cells [nTPM]":"32.8","Single Cell Type RNA - Late spermatids [nTPM]":"9.3","Single Cell Type RNA - Leydig cells [nTPM]":"29.2","Single Cell Type RNA - Macrophages [nTPM]":"34.8","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"202.4","Single Cell Type RNA - monocytes [nTPM]":"16.5","Single Cell Type RNA - Muller glia cells [nTPM]":"21.4","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"74.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"84.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.1","Single Cell Type RNA - Paneth cells [nTPM]":"31.4","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"53.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"21.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"50.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"147.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"11.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"31.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.8","Single Cell Type RNA - T-cells [nTPM]":"26.4","Single Cell Type RNA - Theca cells [nTPM]":"13.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.0","Single Cell Type RNA - Urothelial cells [nTPM]":"15.8"},{"Gene":"AKT1","Gene synonym":["AKT","PKB","PRKBA","RAC","RAC-alpha"],"Ensembl":"ENSG00000142208","Gene description":"AKT serine\/threonine kinase 1","Uniprot":["P31749"],"Chromosome":"14","Position":"104769349-104795751","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins","Transporters"],"Biological process":["Apoptosis","Carbohydrate metabolism","Glucose metabolism","Glycogen biosynthesis","Glycogen metabolism","Neurogenesis","Sugar transport","Translation regulation","Transport"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"61.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"61.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"558.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002891","CAB003765"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Microtubules"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 49: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 30: Mammary glandular cells - Lactation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Microtubules"],"Antibody RRID":{"CAB003765":"AB_562035","HPA002891":"AB_1078123"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.17e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.83e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"71.5","Tissue RNA - adrenal gland [nTPM]":"102.7","Tissue RNA - amygdala [nTPM]":"45.9","Tissue RNA - appendix [nTPM]":"57.7","Tissue RNA - basal ganglia [nTPM]":"45.5","Tissue RNA - bone marrow [nTPM]":"51.2","Tissue RNA - breast [nTPM]":"61.2","Tissue RNA - cerebellum [nTPM]":"43.7","Tissue RNA - cerebral cortex [nTPM]":"53.2","Tissue RNA - cervix [nTPM]":"52.0","Tissue RNA - choroid plexus [nTPM]":"50.4","Tissue RNA - colon [nTPM]":"85.0","Tissue RNA - duodenum [nTPM]":"50.8","Tissue RNA - endometrium 1 [nTPM]":"59.5","Tissue RNA - epididymis [nTPM]":"23.2","Tissue RNA - esophagus [nTPM]":"70.7","Tissue RNA - fallopian tube [nTPM]":"53.7","Tissue RNA - gallbladder [nTPM]":"50.0","Tissue RNA - heart muscle [nTPM]":"105.9","Tissue RNA - hippocampal formation [nTPM]":"45.2","Tissue RNA - hypothalamus [nTPM]":"44.3","Tissue RNA - kidney [nTPM]":"54.3","Tissue RNA - liver [nTPM]":"97.3","Tissue RNA - lung [nTPM]":"69.2","Tissue RNA - lymph node [nTPM]":"51.9","Tissue RNA - medulla oblongata [nTPM]":"50.5","Tissue RNA - midbrain [nTPM]":"45.7","Tissue RNA - ovary [nTPM]":"43.7","Tissue RNA - pancreas [nTPM]":"94.3","Tissue RNA - parathyroid gland [nTPM]":"53.0","Tissue RNA - pituitary gland [nTPM]":"35.9","Tissue RNA - placenta [nTPM]":"55.4","Tissue RNA - pons [nTPM]":"45.0","Tissue RNA - prostate [nTPM]":"67.2","Tissue RNA - rectum [nTPM]":"39.6","Tissue RNA - retina [nTPM]":"25.1","Tissue RNA - salivary gland [nTPM]":"67.7","Tissue RNA - seminal vesicle [nTPM]":"73.0","Tissue RNA - skeletal muscle [nTPM]":"58.1","Tissue RNA - skin 1 [nTPM]":"45.0","Tissue RNA - small intestine [nTPM]":"53.3","Tissue RNA - smooth muscle [nTPM]":"63.4","Tissue RNA - spinal cord [nTPM]":"47.4","Tissue RNA - spleen [nTPM]":"63.7","Tissue RNA - stomach 1 [nTPM]":"77.8","Tissue RNA - testis [nTPM]":"23.9","Tissue RNA - thalamus [nTPM]":"48.0","Tissue RNA - thymus [nTPM]":"52.4","Tissue RNA - thyroid gland [nTPM]":"52.3","Tissue RNA - tongue [nTPM]":"64.9","Tissue RNA - tonsil [nTPM]":"40.3","Tissue RNA - urinary bladder [nTPM]":"72.6","Tissue RNA - vagina [nTPM]":"48.4","Tissue RNA - white matter [nTPM]":"43.3","Cell RNA - A-431 [nTPM]":"77.3","Cell RNA - A549 [nTPM]":"150.5","Cell RNA - AF22 [nTPM]":"124.6","Cell RNA - AN3-CA [nTPM]":"186.9","Cell RNA - ASC diff [nTPM]":"95.2","Cell RNA - ASC TERT1 [nTPM]":"97.7","Cell RNA - BEWO [nTPM]":"136.9","Cell RNA - BJ [nTPM]":"142.3","Cell RNA - BJ hTERT+ [nTPM]":"171.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"204.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"163.6","Cell RNA - CACO-2 [nTPM]":"96.8","Cell RNA - CAPAN-2 [nTPM]":"92.8","Cell RNA - Daudi [nTPM]":"91.2","Cell RNA - EFO-21 [nTPM]":"105.5","Cell RNA - fHDF\/TERT166 [nTPM]":"196.6","Cell RNA - GAMG [nTPM]":"102.8","Cell RNA - HaCaT [nTPM]":"99.4","Cell RNA - HAP1 [nTPM]":"89.5","Cell RNA - HBEC3-KT [nTPM]":"131.9","Cell RNA - HBF TERT88 [nTPM]":"90.1","Cell RNA - HDLM-2 [nTPM]":"214.3","Cell RNA - HEK 293 [nTPM]":"36.2","Cell RNA - HEL [nTPM]":"70.6","Cell RNA - HeLa [nTPM]":"90.4","Cell RNA - Hep G2 [nTPM]":"103.2","Cell RNA - HHSteC [nTPM]":"104.6","Cell RNA - HL-60 [nTPM]":"117.5","Cell RNA - HMC-1 [nTPM]":"178.0","Cell RNA - HSkMC [nTPM]":"140.0","Cell RNA - hTCEpi [nTPM]":"109.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"102.9","Cell RNA - hTERT-HME1 [nTPM]":"68.1","Cell RNA - hTERT-RPE1 [nTPM]":"98.2","Cell RNA - HUVEC TERT2 [nTPM]":"154.4","Cell RNA - JURKAT [nTPM]":"87.5","Cell RNA - K-562 [nTPM]":"62.1","Cell RNA - Karpas-707 [nTPM]":"102.2","Cell RNA - LHCN-M2 [nTPM]":"134.1","Cell RNA - MCF7 [nTPM]":"558.3","Cell RNA - MOLT-4 [nTPM]":"145.3","Cell RNA - NB-4 [nTPM]":"146.8","Cell RNA - NTERA-2 [nTPM]":"32.6","Cell RNA - OE19 [nTPM]":"153.5","Cell RNA - PC-3 [nTPM]":"107.2","Cell RNA - REH [nTPM]":"137.5","Cell RNA - RH-30 [nTPM]":"111.9","Cell RNA - RPMI-8226 [nTPM]":"60.5","Cell RNA - RPTEC TERT1 [nTPM]":"94.8","Cell RNA - RT4 [nTPM]":"189.5","Cell RNA - SCLC-21H [nTPM]":"141.2","Cell RNA - SH-SY5Y [nTPM]":"117.2","Cell RNA - SiHa [nTPM]":"117.3","Cell RNA - SK-BR-3 [nTPM]":"152.2","Cell RNA - SK-MEL-30 [nTPM]":"88.9","Cell RNA - SuSa [nTPM]":"56.8","Cell RNA - T-47d [nTPM]":"195.7","Cell RNA - THP-1 [nTPM]":"170.2","Cell RNA - TIME [nTPM]":"123.5","Cell RNA - U-138 MG [nTPM]":"133.2","Cell RNA - U-2 OS [nTPM]":"63.2","Cell RNA - U-2197 [nTPM]":"192.3","Cell RNA - U-251 MG [nTPM]":"145.1","Cell RNA - U-266\/70 [nTPM]":"105.4","Cell RNA - U-266\/84 [nTPM]":"52.6","Cell RNA - U-698 [nTPM]":"80.7","Cell RNA - U-87 MG [nTPM]":"113.7","Cell RNA - U-937 [nTPM]":"96.7","Cell RNA - WM-115 [nTPM]":"162.0","Blood RNA - basophil [nTPM]":"6.4","Blood RNA - classical monocyte [nTPM]":"9.9","Blood RNA - eosinophil [nTPM]":"61.5","Blood RNA - gdT-cell [nTPM]":"10.0","Blood RNA - intermediate monocyte [nTPM]":"10.3","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"8.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"7.0","Blood RNA - naive B-cell [nTPM]":"7.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"22.6","Blood RNA - NK-cell [nTPM]":"11.0","Blood RNA - non-classical monocyte [nTPM]":"12.4","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"9.0","Blood RNA - total PBMC [nTPM]":"6.3","Brain RNA - amygdala [nTPM]":"45.9","Brain RNA - basal ganglia [nTPM]":"45.5","Brain RNA - cerebellum [nTPM]":"43.7","Brain RNA - cerebral cortex [nTPM]":"53.2","Brain RNA - hippocampal formation [nTPM]":"45.2","Brain RNA - hypothalamus [nTPM]":"44.3","Brain RNA - medulla oblongata [nTPM]":"50.5","Brain RNA - midbrain [nTPM]":"45.7","Brain RNA - pons [nTPM]":"45.0","Brain RNA - spinal cord [nTPM]":"47.4","Brain RNA - thalamus [nTPM]":"48.0","Brain RNA - white matter [nTPM]":"43.3","Single Cell Type RNA - Adipocytes [nTPM]":"45.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"13.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"17.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"26.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"39.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"17.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"54.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"23.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.1","Single Cell Type RNA - Endothelial cells [nTPM]":"27.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.0","Single Cell Type RNA - Erythroid cells [nTPM]":"11.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"35.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"31.8","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"40.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"23.2","Single Cell Type RNA - Hepatocytes [nTPM]":"42.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.2","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"37.3","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"23.3","Single Cell Type RNA - Langerhans cells [nTPM]":"21.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.6","Single Cell Type RNA - Macrophages [nTPM]":"28.0","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"23.1","Single Cell Type RNA - Muller glia cells [nTPM]":"51.2","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"53.3","Single Cell Type RNA - Paneth cells [nTPM]":"22.1","Single Cell Type RNA - Peritubular cells [nTPM]":"30.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.4","Single Cell Type RNA - T-cells [nTPM]":"23.3","Single Cell Type RNA - Theca cells [nTPM]":"34.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.7","Single Cell Type RNA - Urothelial cells [nTPM]":"33.4"},{"Gene":"AKT2","Gene synonym":["PKB\u00c3\u017d\u00c2\u00b2"],"Ensembl":"ENSG00000105221","Gene description":"AKT serine\/threonine kinase 2","Uniprot":["P31751"],"Chromosome":"19","Position":"40230317-40285536","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Apoptosis","Carbohydrate metabolism","Glucose metabolism","Glycogen biosynthesis","Glycogen metabolism","Sugar transport","Translation regulation","Transport"],"Molecular function":["Developmental protein","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004204","HPA064521"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm","Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004204":"AB_626659","HPA064521":"AB_2685278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.74e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Tissue RNA - adipose tissue [nTPM]":"62.8","Tissue RNA - adrenal gland [nTPM]":"40.0","Tissue RNA - amygdala [nTPM]":"31.7","Tissue RNA - appendix [nTPM]":"37.3","Tissue RNA - basal ganglia [nTPM]":"31.3","Tissue RNA - bone marrow [nTPM]":"48.4","Tissue RNA - breast [nTPM]":"38.6","Tissue RNA - cerebellum [nTPM]":"58.3","Tissue RNA - cerebral cortex [nTPM]":"40.0","Tissue RNA - cervix [nTPM]":"49.8","Tissue RNA - choroid plexus [nTPM]":"55.1","Tissue RNA - colon [nTPM]":"42.3","Tissue RNA - duodenum [nTPM]":"24.5","Tissue RNA - endometrium 1 [nTPM]":"43.5","Tissue RNA - epididymis [nTPM]":"49.4","Tissue RNA - esophagus [nTPM]":"42.5","Tissue RNA - fallopian tube [nTPM]":"46.1","Tissue RNA - gallbladder [nTPM]":"25.1","Tissue RNA - heart muscle [nTPM]":"40.8","Tissue RNA - hippocampal formation [nTPM]":"31.5","Tissue RNA - hypothalamus [nTPM]":"24.5","Tissue RNA - kidney [nTPM]":"52.2","Tissue RNA - liver [nTPM]":"59.2","Tissue RNA - lung [nTPM]":"30.7","Tissue RNA - lymph node [nTPM]":"38.1","Tissue RNA - medulla oblongata [nTPM]":"32.0","Tissue RNA - midbrain [nTPM]":"26.0","Tissue RNA - ovary [nTPM]":"53.9","Tissue RNA - pancreas [nTPM]":"41.9","Tissue RNA - parathyroid gland [nTPM]":"58.5","Tissue RNA - pituitary gland [nTPM]":"47.8","Tissue RNA - placenta [nTPM]":"27.6","Tissue RNA - pons [nTPM]":"26.3","Tissue RNA - prostate [nTPM]":"41.2","Tissue RNA - rectum [nTPM]":"23.3","Tissue RNA - retina [nTPM]":"41.2","Tissue RNA - salivary gland [nTPM]":"32.5","Tissue RNA - seminal vesicle [nTPM]":"45.0","Tissue RNA - skeletal muscle [nTPM]":"101.3","Tissue RNA - skin 1 [nTPM]":"39.4","Tissue RNA - small intestine [nTPM]":"35.6","Tissue RNA - smooth muscle [nTPM]":"34.2","Tissue RNA - spinal cord [nTPM]":"22.1","Tissue RNA - spleen [nTPM]":"38.1","Tissue RNA - stomach 1 [nTPM]":"33.1","Tissue RNA - testis [nTPM]":"29.7","Tissue RNA - thalamus [nTPM]":"28.0","Tissue RNA - thymus [nTPM]":"53.4","Tissue RNA - thyroid gland [nTPM]":"100.1","Tissue RNA - tongue [nTPM]":"118.7","Tissue RNA - tonsil [nTPM]":"37.0","Tissue RNA - urinary bladder [nTPM]":"39.8","Tissue RNA - vagina [nTPM]":"41.5","Tissue RNA - white matter [nTPM]":"35.2","Cell RNA - A-431 [nTPM]":"66.2","Cell RNA - A549 [nTPM]":"160.1","Cell RNA - AF22 [nTPM]":"63.1","Cell RNA - AN3-CA [nTPM]":"61.5","Cell RNA - ASC diff [nTPM]":"72.0","Cell RNA - ASC TERT1 [nTPM]":"88.9","Cell RNA - BEWO [nTPM]":"32.5","Cell RNA - BJ [nTPM]":"41.7","Cell RNA - BJ hTERT+ [nTPM]":"63.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"77.9","Cell RNA - CACO-2 [nTPM]":"71.8","Cell RNA - CAPAN-2 [nTPM]":"60.8","Cell RNA - Daudi [nTPM]":"67.4","Cell RNA - EFO-21 [nTPM]":"36.8","Cell RNA - fHDF\/TERT166 [nTPM]":"96.3","Cell RNA - GAMG [nTPM]":"37.2","Cell RNA - HaCaT [nTPM]":"28.2","Cell RNA - HAP1 [nTPM]":"66.8","Cell RNA - HBEC3-KT [nTPM]":"90.0","Cell RNA - HBF TERT88 [nTPM]":"56.1","Cell RNA - HDLM-2 [nTPM]":"62.5","Cell RNA - HEK 293 [nTPM]":"74.3","Cell RNA - HEL [nTPM]":"43.4","Cell RNA - HeLa [nTPM]":"116.5","Cell RNA - Hep G2 [nTPM]":"44.7","Cell RNA - HHSteC [nTPM]":"45.8","Cell RNA - HL-60 [nTPM]":"50.7","Cell RNA - HMC-1 [nTPM]":"50.5","Cell RNA - HSkMC [nTPM]":"82.7","Cell RNA - hTCEpi [nTPM]":"53.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"58.6","Cell RNA - hTERT-HME1 [nTPM]":"56.4","Cell RNA - hTERT-RPE1 [nTPM]":"71.9","Cell RNA - HUVEC TERT2 [nTPM]":"19.0","Cell RNA - JURKAT [nTPM]":"73.0","Cell RNA - K-562 [nTPM]":"57.3","Cell RNA - Karpas-707 [nTPM]":"67.5","Cell RNA - LHCN-M2 [nTPM]":"49.8","Cell RNA - MCF7 [nTPM]":"54.6","Cell RNA - MOLT-4 [nTPM]":"81.1","Cell RNA - NB-4 [nTPM]":"24.7","Cell RNA - NTERA-2 [nTPM]":"31.7","Cell RNA - OE19 [nTPM]":"73.7","Cell RNA - PC-3 [nTPM]":"41.5","Cell RNA - REH [nTPM]":"54.2","Cell RNA - RH-30 [nTPM]":"32.1","Cell RNA - RPMI-8226 [nTPM]":"48.5","Cell RNA - RPTEC TERT1 [nTPM]":"68.3","Cell RNA - RT4 [nTPM]":"105.7","Cell RNA - SCLC-21H [nTPM]":"82.7","Cell RNA - SH-SY5Y [nTPM]":"49.8","Cell RNA - SiHa [nTPM]":"43.3","Cell RNA - SK-BR-3 [nTPM]":"75.0","Cell RNA - SK-MEL-30 [nTPM]":"35.0","Cell RNA - SuSa [nTPM]":"62.5","Cell RNA - T-47d [nTPM]":"59.8","Cell RNA - THP-1 [nTPM]":"64.9","Cell RNA - TIME [nTPM]":"18.8","Cell RNA - U-138 MG [nTPM]":"52.7","Cell RNA - U-2 OS [nTPM]":"51.5","Cell RNA - U-2197 [nTPM]":"47.3","Cell RNA - U-251 MG [nTPM]":"67.6","Cell RNA - U-266\/70 [nTPM]":"61.5","Cell RNA - U-266\/84 [nTPM]":"59.0","Cell RNA - U-698 [nTPM]":"56.4","Cell RNA - U-87 MG [nTPM]":"52.6","Cell RNA - U-937 [nTPM]":"59.7","Cell RNA - WM-115 [nTPM]":"44.3","Blood RNA - basophil [nTPM]":"5.7","Blood RNA - classical monocyte [nTPM]":"2.6","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"2.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"4.0","Blood RNA - NK-cell [nTPM]":"1.7","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"4.9","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"31.7","Brain RNA - basal ganglia [nTPM]":"31.3","Brain RNA - cerebellum [nTPM]":"58.3","Brain RNA - cerebral cortex [nTPM]":"40.0","Brain RNA - hippocampal formation [nTPM]":"31.5","Brain RNA - hypothalamus [nTPM]":"24.5","Brain RNA - medulla oblongata [nTPM]":"32.0","Brain RNA - midbrain [nTPM]":"26.0","Brain RNA - pons [nTPM]":"26.3","Brain RNA - spinal cord [nTPM]":"22.1","Brain RNA - thalamus [nTPM]":"28.0","Brain RNA - white matter [nTPM]":"35.2","Single Cell Type RNA - Adipocytes [nTPM]":"18.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.9","Single Cell Type RNA - Astrocytes [nTPM]":"51.2","Single Cell Type RNA - B-cells [nTPM]":"33.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"20.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"26.2","Single Cell Type RNA - Bipolar cells [nTPM]":"67.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"18.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"31.3","Single Cell Type RNA - dendritic cells [nTPM]":"26.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"19.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.7","Single Cell Type RNA - Endothelial cells [nTPM]":"17.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"30.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.2","Single Cell Type RNA - Fibroblasts [nTPM]":"27.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"44.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"87.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.3","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"25.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.1","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"23.2","Single Cell Type RNA - Langerhans cells [nTPM]":"17.5","Single Cell Type RNA - Late spermatids [nTPM]":"10.5","Single Cell Type RNA - Leydig cells [nTPM]":"42.9","Single Cell Type RNA - Macrophages [nTPM]":"20.0","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"21.7","Single Cell Type RNA - Muller glia cells [nTPM]":"46.2","Single Cell Type RNA - NK-cells [nTPM]":"50.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"40.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.9","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"30.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"97.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"25.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.8","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"31.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.7","Single Cell Type RNA - T-cells [nTPM]":"23.1","Single Cell Type RNA - Theca cells [nTPM]":"56.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"29.4"},{"Gene":"ALK","Gene synonym":["CD246"],"Ensembl":"ENSG00000171094","Gene description":"ALK receptor tyrosine kinase","Uniprot":["Q9UM73"],"Chromosome":"2","Position":"29192774-29921586","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"brain":"10.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Inhibitory neurons":"274.2","Oligodendrocyte precursor cells":"433.8"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"1.0","melanoma":"1.5","ovarian cancer":"0.7","thyroid cancer":"1.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"SH-SY5Y":"31.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010694"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA010694":"AB_1078133"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.7","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"3.9","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.1","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"10.9","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.5","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"4.3","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"31.7","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"5.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"0.7","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"3.9","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"10.9","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"2.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"66.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"42.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"274.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"41.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"433.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"AMER1","Gene synonym":["FAM123B","FLJ39827","RP11-403E24.2","WTX"],"Ensembl":"ENSG00000184675","Gene description":"APC membrane recruitment protein 1","Uniprot":["Q5JTC6"],"Chromosome":"X","Position":"64185117-64205708","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"15.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Sertoli cells":"6.6","Theca cells":"6.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"15.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065214","HPA065265"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Vesicles","Plasma membrane"],"Antibody RRID":{"HPA065214":"AB_2685435","HPA065265":"AB_2685450"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.1","Tissue RNA - adrenal gland [nTPM]":"1.4","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"1.3","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"1.5","Tissue RNA - duodenum [nTPM]":"1.5","Tissue RNA - endometrium 1 [nTPM]":"1.9","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"1.3","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"1.8","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"1.2","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"1.7","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"4.1","Tissue RNA - skin 1 [nTPM]":"2.2","Tissue RNA - small intestine [nTPM]":"1.3","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"1.4","Tissue RNA - tongue [nTPM]":"15.3","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"3.1","Cell RNA - A549 [nTPM]":"2.2","Cell RNA - AF22 [nTPM]":"5.8","Cell RNA - AN3-CA [nTPM]":"4.6","Cell RNA - ASC diff [nTPM]":"2.2","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"4.7","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"1.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"7.3","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"3.0","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"4.3","Cell RNA - HAP1 [nTPM]":"12.5","Cell RNA - HBEC3-KT [nTPM]":"4.1","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"2.5","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"3.7","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"4.9","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"7.7","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"3.0","Cell RNA - hTCEpi [nTPM]":"5.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.6","Cell RNA - hTERT-HME1 [nTPM]":"3.2","Cell RNA - hTERT-RPE1 [nTPM]":"1.7","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"5.6","Cell RNA - Karpas-707 [nTPM]":"5.9","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"3.7","Cell RNA - MOLT-4 [nTPM]":"5.2","Cell RNA - NB-4 [nTPM]":"4.0","Cell RNA - NTERA-2 [nTPM]":"15.6","Cell RNA - OE19 [nTPM]":"4.0","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"11.7","Cell RNA - RH-30 [nTPM]":"9.4","Cell RNA - RPMI-8226 [nTPM]":"4.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.9","Cell RNA - RT4 [nTPM]":"1.0","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"3.9","Cell RNA - SiHa [nTPM]":"3.7","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"1.9","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"2.5","Cell RNA - U-2 OS [nTPM]":"5.8","Cell RNA - U-2197 [nTPM]":"6.7","Cell RNA - U-251 MG [nTPM]":"1.9","Cell RNA - U-266\/70 [nTPM]":"3.0","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"4.4","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"8.7","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"3.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"2.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"6.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"APC","Gene synonym":["DP2","DP2.5","DP3","PPP1R46"],"Ensembl":"ENSG00000134982","Gene description":"APC regulator of WNT signaling pathway","Uniprot":["P25054"],"Chromosome":"5","Position":"112707498-112846239","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"52.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"536.4","Bipolar cells":"196.9","Excitatory neurons":"165.8","Inhibitory neurons":"236.4","Oligodendrocyte precursor cells":"196.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA013349","HPA013362"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 65: Brain - Ion transport","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Golgi apparatus"],"Antibody RRID":{"HPA013349":"AB_1844913","HPA013362":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.9","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"28.4","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"26.0","Tissue RNA - bone marrow [nTPM]":"9.1","Tissue RNA - breast [nTPM]":"5.7","Tissue RNA - cerebellum [nTPM]":"23.1","Tissue RNA - cerebral cortex [nTPM]":"31.0","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"5.6","Tissue RNA - epididymis [nTPM]":"3.3","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"4.9","Tissue RNA - heart muscle [nTPM]":"7.2","Tissue RNA - hippocampal formation [nTPM]":"52.8","Tissue RNA - hypothalamus [nTPM]":"27.4","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"5.7","Tissue RNA - lung [nTPM]":"6.2","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"32.1","Tissue RNA - midbrain [nTPM]":"30.7","Tissue RNA - ovary [nTPM]":"6.6","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"3.9","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"39.0","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"20.0","Tissue RNA - salivary gland [nTPM]":"3.8","Tissue RNA - seminal vesicle [nTPM]":"4.1","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"5.7","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"16.0","Tissue RNA - spleen [nTPM]":"6.1","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"5.1","Tissue RNA - thalamus [nTPM]":"37.9","Tissue RNA - thymus [nTPM]":"8.5","Tissue RNA - thyroid gland [nTPM]":"5.9","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"5.9","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"3.6","Tissue RNA - white matter [nTPM]":"20.9","Cell RNA - A-431 [nTPM]":"11.3","Cell RNA - A549 [nTPM]":"10.1","Cell RNA - AF22 [nTPM]":"16.8","Cell RNA - AN3-CA [nTPM]":"12.2","Cell RNA - ASC diff [nTPM]":"13.4","Cell RNA - ASC TERT1 [nTPM]":"11.3","Cell RNA - BEWO [nTPM]":"6.7","Cell RNA - BJ [nTPM]":"17.9","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.5","Cell RNA - CACO-2 [nTPM]":"8.2","Cell RNA - CAPAN-2 [nTPM]":"8.9","Cell RNA - Daudi [nTPM]":"22.0","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"23.1","Cell RNA - GAMG [nTPM]":"15.5","Cell RNA - HaCaT [nTPM]":"9.0","Cell RNA - HAP1 [nTPM]":"17.4","Cell RNA - HBEC3-KT [nTPM]":"14.6","Cell RNA - HBF TERT88 [nTPM]":"15.9","Cell RNA - HDLM-2 [nTPM]":"13.2","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"14.9","Cell RNA - Hep G2 [nTPM]":"6.2","Cell RNA - HHSteC [nTPM]":"6.6","Cell RNA - HL-60 [nTPM]":"8.4","Cell RNA - HMC-1 [nTPM]":"8.6","Cell RNA - HSkMC [nTPM]":"9.3","Cell RNA - hTCEpi [nTPM]":"9.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.6","Cell RNA - hTERT-HME1 [nTPM]":"10.8","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"13.6","Cell RNA - JURKAT [nTPM]":"10.2","Cell RNA - K-562 [nTPM]":"20.9","Cell RNA - Karpas-707 [nTPM]":"7.2","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"7.8","Cell RNA - MOLT-4 [nTPM]":"9.6","Cell RNA - NB-4 [nTPM]":"4.2","Cell RNA - NTERA-2 [nTPM]":"6.0","Cell RNA - OE19 [nTPM]":"6.1","Cell RNA - PC-3 [nTPM]":"3.6","Cell RNA - REH [nTPM]":"8.1","Cell RNA - RH-30 [nTPM]":"20.8","Cell RNA - RPMI-8226 [nTPM]":"10.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.9","Cell RNA - RT4 [nTPM]":"14.1","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"10.1","Cell RNA - SiHa [nTPM]":"16.9","Cell RNA - SK-BR-3 [nTPM]":"6.5","Cell RNA - SK-MEL-30 [nTPM]":"7.1","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"9.1","Cell RNA - THP-1 [nTPM]":"6.7","Cell RNA - TIME [nTPM]":"22.8","Cell RNA - U-138 MG [nTPM]":"19.6","Cell RNA - U-2 OS [nTPM]":"9.5","Cell RNA - U-2197 [nTPM]":"19.5","Cell RNA - U-251 MG [nTPM]":"13.6","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"9.5","Cell RNA - U-698 [nTPM]":"8.2","Cell RNA - U-87 MG [nTPM]":"10.8","Cell RNA - U-937 [nTPM]":"15.3","Cell RNA - WM-115 [nTPM]":"11.2","Blood RNA - basophil [nTPM]":"11.8","Blood RNA - classical monocyte [nTPM]":"2.5","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"2.9","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.4","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"11.4","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"2.4","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"28.4","Brain RNA - basal ganglia [nTPM]":"26.0","Brain RNA - cerebellum [nTPM]":"23.1","Brain RNA - cerebral cortex [nTPM]":"31.0","Brain RNA - hippocampal formation [nTPM]":"52.8","Brain RNA - hypothalamus [nTPM]":"27.4","Brain RNA - medulla oblongata [nTPM]":"32.1","Brain RNA - midbrain [nTPM]":"30.7","Brain RNA - pons [nTPM]":"39.0","Brain RNA - spinal cord [nTPM]":"16.0","Brain RNA - thalamus [nTPM]":"37.9","Brain RNA - white matter [nTPM]":"20.9","Single Cell Type RNA - Adipocytes [nTPM]":"40.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"23.6","Single Cell Type RNA - Astrocytes [nTPM]":"536.4","Single Cell Type RNA - B-cells [nTPM]":"21.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"196.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"56.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"20.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"66.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.4","Single Cell Type RNA - dendritic cells [nTPM]":"28.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"28.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.7","Single Cell Type RNA - Early spermatids [nTPM]":"10.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"27.6","Single Cell Type RNA - Endothelial cells [nTPM]":"31.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"165.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.7","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"13.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.3","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"236.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.5","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"27.8","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"85.3","Single Cell Type RNA - monocytes [nTPM]":"30.7","Single Cell Type RNA - Muller glia cells [nTPM]":"23.4","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"196.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"150.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.3","Single Cell Type RNA - Paneth cells [nTPM]":"34.7","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"22.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"44.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.2","Single Cell Type RNA - Spermatogonia [nTPM]":"30.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"22.4","Single Cell Type RNA - Theca cells [nTPM]":"27.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.0","Single Cell Type RNA - Urothelial cells [nTPM]":"8.9"},{"Gene":"APC2","Gene synonym":["APCL"],"Ensembl":"ENSG00000115266","Gene description":"APC regulator of WNT signaling pathway 2","Uniprot":["O95996"],"Chromosome":"19","Position":"1446302-1473244","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Disease variant","Lissencephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"brain":"64.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"142.4","Bipolar cells":"50.4","Excitatory neurons":"26.8","Horizontal cells":"45.4","Inhibitory neurons":"27.5","Muller glia cells":"29.4","Oligodendrocyte precursor cells":"28.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"27","RNA cancer specific FPKM":{"glioma":"17.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"7.8","SCLC-21H":"9.3","SH-SY5Y":"31.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA078002"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytokinetic bridge","Midbody","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Cytokinetic bridge","Midbody"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA078002":"AB_2686874"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"41.5","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"27.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"41.4","Tissue RNA - cerebral cortex [nTPM]":"42.4","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.1","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"37.1","Tissue RNA - hypothalamus [nTPM]":"20.8","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"64.5","Tissue RNA - midbrain [nTPM]":"42.3","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"54.9","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"2.7","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.4","Tissue RNA - smooth muscle [nTPM]":"0.1","Tissue RNA - spinal cord [nTPM]":"38.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"54.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"49.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.6","Cell RNA - AF22 [nTPM]":"7.8","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.5","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"9.3","Cell RNA - SH-SY5Y [nTPM]":"31.7","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.5","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"1.7","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"41.5","Brain RNA - basal ganglia [nTPM]":"27.3","Brain RNA - cerebellum [nTPM]":"41.4","Brain RNA - cerebral cortex [nTPM]":"42.4","Brain RNA - hippocampal formation [nTPM]":"37.1","Brain RNA - hypothalamus [nTPM]":"20.8","Brain RNA - medulla oblongata [nTPM]":"64.5","Brain RNA - midbrain [nTPM]":"42.3","Brain RNA - pons [nTPM]":"54.9","Brain RNA - spinal cord [nTPM]":"38.3","Brain RNA - thalamus [nTPM]":"54.6","Brain RNA - white matter [nTPM]":"49.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"142.4","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"50.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"26.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"29.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"17.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"AR","Gene synonym":["AIS","DHTR","HUMARA","NR3C4","SBMA","SMAX1"],"Ensembl":"ENSG00000169083","Gene description":"Androgen receptor","Uniprot":["P10275"],"Chromosome":"X","Position":"67544021-67730619","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Nuclear receptors","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration","Pseudohermaphroditism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"38.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"93.7","Granulosa cells":"104.8","Hepatocytes":"269.2","Leydig cells":"77.9","Peritubular cells":"86.5","Skeletal myocytes":"75.0"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"15.6","prostate cancer":"16.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"13.3","BJ hTERT+":"10.3","HAP1":"14.9","LHCN-M2":"16.1","RH-30":"23.6","T-47d":"10.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000001","HPA004733","CAB065764"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB000001":"AB_2060174","CAB065764":"AB_10620739","HPA004733":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.10e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.77e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.03e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.23e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.7","Tissue RNA - adrenal gland [nTPM]":"1.0","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"8.7","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"23.6","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"18.6","Tissue RNA - epididymis [nTPM]":"16.1","Tissue RNA - esophagus [nTPM]":"1.2","Tissue RNA - fallopian tube [nTPM]":"20.7","Tissue RNA - gallbladder [nTPM]":"2.0","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"3.5","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"38.2","Tissue RNA - lung [nTPM]":"1.5","Tissue RNA - lymph node [nTPM]":"0.3","Tissue RNA - medulla oblongata [nTPM]":"3.5","Tissue RNA - midbrain [nTPM]":"2.6","Tissue RNA - ovary [nTPM]":"14.6","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"16.5","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.4","Tissue RNA - seminal vesicle [nTPM]":"18.2","Tissue RNA - skeletal muscle [nTPM]":"13.9","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"9.5","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"1.3","Tissue RNA - stomach 1 [nTPM]":"1.5","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"2.7","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"13.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"7.3","Cell RNA - BJ hTERT+ [nTPM]":"10.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"14.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.8","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"5.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.8","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"3.9","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"4.6","Cell RNA - Karpas-707 [nTPM]":"2.2","Cell RNA - LHCN-M2 [nTPM]":"16.1","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"5.4","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"23.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"10.9","Cell RNA - THP-1 [nTPM]":"7.6","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"3.5","Brain RNA - medulla oblongata [nTPM]":"3.5","Brain RNA - midbrain [nTPM]":"2.6","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.0","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"93.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"37.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"10.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.5","Single Cell Type RNA - dendritic cells [nTPM]":"14.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"104.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.0","Single Cell Type RNA - Hepatocytes [nTPM]":"269.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"3.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"86.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"75.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"37.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.0"},{"Gene":"ARAF","Gene synonym":["ARAF1"],"Ensembl":"ENSG00000078061","Gene description":"A-Raf proto-oncogene, serine\/threonine kinase","Uniprot":["P10398"],"Chromosome":"X","Position":"47561205-47571908","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA066326"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA066326":"AB_2685659"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.65e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.45e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"37.7","Tissue RNA - adrenal gland [nTPM]":"41.7","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"36.9","Tissue RNA - basal ganglia [nTPM]":"20.8","Tissue RNA - bone marrow [nTPM]":"102.3","Tissue RNA - breast [nTPM]":"36.2","Tissue RNA - cerebellum [nTPM]":"19.2","Tissue RNA - cerebral cortex [nTPM]":"21.1","Tissue RNA - cervix [nTPM]":"34.8","Tissue RNA - choroid plexus [nTPM]":"22.6","Tissue RNA - colon [nTPM]":"40.9","Tissue RNA - duodenum [nTPM]":"37.8","Tissue RNA - endometrium 1 [nTPM]":"36.6","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"32.2","Tissue RNA - fallopian tube [nTPM]":"35.0","Tissue RNA - gallbladder [nTPM]":"32.5","Tissue RNA - heart muscle [nTPM]":"50.8","Tissue RNA - hippocampal formation [nTPM]":"17.1","Tissue RNA - hypothalamus [nTPM]":"18.0","Tissue RNA - kidney [nTPM]":"44.6","Tissue RNA - liver [nTPM]":"55.7","Tissue RNA - lung [nTPM]":"39.4","Tissue RNA - lymph node [nTPM]":"40.4","Tissue RNA - medulla oblongata [nTPM]":"22.8","Tissue RNA - midbrain [nTPM]":"20.5","Tissue RNA - ovary [nTPM]":"39.5","Tissue RNA - pancreas [nTPM]":"59.1","Tissue RNA - parathyroid gland [nTPM]":"51.8","Tissue RNA - pituitary gland [nTPM]":"27.7","Tissue RNA - placenta [nTPM]":"31.3","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"40.9","Tissue RNA - rectum [nTPM]":"33.3","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"45.1","Tissue RNA - seminal vesicle [nTPM]":"34.6","Tissue RNA - skeletal muscle [nTPM]":"136.3","Tissue RNA - skin 1 [nTPM]":"36.0","Tissue RNA - small intestine [nTPM]":"39.7","Tissue RNA - smooth muscle [nTPM]":"31.3","Tissue RNA - spinal cord [nTPM]":"18.8","Tissue RNA - spleen [nTPM]":"46.1","Tissue RNA - stomach 1 [nTPM]":"46.7","Tissue RNA - testis [nTPM]":"12.0","Tissue RNA - thalamus [nTPM]":"21.0","Tissue RNA - thymus [nTPM]":"38.0","Tissue RNA - thyroid gland [nTPM]":"39.4","Tissue RNA - tongue [nTPM]":"85.6","Tissue RNA - tonsil [nTPM]":"31.5","Tissue RNA - urinary bladder [nTPM]":"36.1","Tissue RNA - vagina [nTPM]":"30.8","Tissue RNA - white matter [nTPM]":"20.4","Cell RNA - A-431 [nTPM]":"49.1","Cell RNA - A549 [nTPM]":"69.5","Cell RNA - AF22 [nTPM]":"29.2","Cell RNA - AN3-CA [nTPM]":"46.9","Cell RNA - ASC diff [nTPM]":"43.5","Cell RNA - ASC TERT1 [nTPM]":"34.2","Cell RNA - BEWO [nTPM]":"39.0","Cell RNA - BJ [nTPM]":"40.3","Cell RNA - BJ hTERT+ [nTPM]":"42.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"54.1","Cell RNA - CACO-2 [nTPM]":"57.2","Cell RNA - CAPAN-2 [nTPM]":"58.6","Cell RNA - Daudi [nTPM]":"29.0","Cell RNA - EFO-21 [nTPM]":"32.4","Cell RNA - fHDF\/TERT166 [nTPM]":"54.6","Cell RNA - GAMG [nTPM]":"49.2","Cell RNA - HaCaT [nTPM]":"67.3","Cell RNA - HAP1 [nTPM]":"51.8","Cell RNA - HBEC3-KT [nTPM]":"56.3","Cell RNA - HBF TERT88 [nTPM]":"34.3","Cell RNA - HDLM-2 [nTPM]":"53.5","Cell RNA - HEK 293 [nTPM]":"61.9","Cell RNA - HEL [nTPM]":"29.4","Cell RNA - HeLa [nTPM]":"74.4","Cell RNA - Hep G2 [nTPM]":"30.6","Cell RNA - HHSteC [nTPM]":"61.4","Cell RNA - HL-60 [nTPM]":"58.3","Cell RNA - HMC-1 [nTPM]":"85.1","Cell RNA - HSkMC [nTPM]":"45.0","Cell RNA - hTCEpi [nTPM]":"56.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.2","Cell RNA - hTERT-HME1 [nTPM]":"49.6","Cell RNA - hTERT-RPE1 [nTPM]":"39.2","Cell RNA - HUVEC TERT2 [nTPM]":"45.9","Cell RNA - JURKAT [nTPM]":"36.0","Cell RNA - K-562 [nTPM]":"55.2","Cell RNA - Karpas-707 [nTPM]":"55.7","Cell RNA - LHCN-M2 [nTPM]":"40.5","Cell RNA - MCF7 [nTPM]":"83.3","Cell RNA - MOLT-4 [nTPM]":"42.6","Cell RNA - NB-4 [nTPM]":"64.0","Cell RNA - NTERA-2 [nTPM]":"41.8","Cell RNA - OE19 [nTPM]":"41.2","Cell RNA - PC-3 [nTPM]":"77.8","Cell RNA - REH [nTPM]":"39.2","Cell RNA - RH-30 [nTPM]":"38.0","Cell RNA - RPMI-8226 [nTPM]":"65.5","Cell RNA - RPTEC TERT1 [nTPM]":"34.4","Cell RNA - RT4 [nTPM]":"46.7","Cell RNA - SCLC-21H [nTPM]":"32.8","Cell RNA - SH-SY5Y [nTPM]":"25.0","Cell RNA - SiHa [nTPM]":"43.7","Cell RNA - SK-BR-3 [nTPM]":"39.7","Cell RNA - SK-MEL-30 [nTPM]":"24.5","Cell RNA - SuSa [nTPM]":"47.0","Cell RNA - T-47d [nTPM]":"74.9","Cell RNA - THP-1 [nTPM]":"43.3","Cell RNA - TIME [nTPM]":"44.2","Cell RNA - U-138 MG [nTPM]":"38.0","Cell RNA - U-2 OS [nTPM]":"42.5","Cell RNA - U-2197 [nTPM]":"76.2","Cell RNA - U-251 MG [nTPM]":"41.4","Cell RNA - U-266\/70 [nTPM]":"71.1","Cell RNA - U-266\/84 [nTPM]":"49.2","Cell RNA - U-698 [nTPM]":"22.5","Cell RNA - U-87 MG [nTPM]":"50.8","Cell RNA - U-937 [nTPM]":"65.3","Cell RNA - WM-115 [nTPM]":"31.1","Blood RNA - basophil [nTPM]":"48.3","Blood RNA - classical monocyte [nTPM]":"47.8","Blood RNA - eosinophil [nTPM]":"61.3","Blood RNA - gdT-cell [nTPM]":"44.1","Blood RNA - intermediate monocyte [nTPM]":"57.8","Blood RNA - MAIT T-cell [nTPM]":"40.3","Blood RNA - memory B-cell [nTPM]":"32.6","Blood RNA - memory CD4 T-cell [nTPM]":"38.4","Blood RNA - memory CD8 T-cell [nTPM]":"40.9","Blood RNA - myeloid DC [nTPM]":"55.2","Blood RNA - naive B-cell [nTPM]":"37.3","Blood RNA - naive CD4 T-cell [nTPM]":"33.5","Blood RNA - naive CD8 T-cell [nTPM]":"40.5","Blood RNA - neutrophil [nTPM]":"37.8","Blood RNA - NK-cell [nTPM]":"38.7","Blood RNA - non-classical monocyte [nTPM]":"67.9","Blood RNA - plasmacytoid DC [nTPM]":"40.4","Blood RNA - T-reg [nTPM]":"41.6","Blood RNA - total PBMC [nTPM]":"50.8","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"20.8","Brain RNA - cerebellum [nTPM]":"19.2","Brain RNA - cerebral cortex [nTPM]":"21.1","Brain RNA - hippocampal formation [nTPM]":"17.1","Brain RNA - hypothalamus [nTPM]":"18.0","Brain RNA - medulla oblongata [nTPM]":"22.8","Brain RNA - midbrain [nTPM]":"20.5","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"18.8","Brain RNA - thalamus [nTPM]":"21.0","Brain RNA - white matter [nTPM]":"20.4","Single Cell Type RNA - Adipocytes [nTPM]":"13.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.2","Single Cell Type RNA - Astrocytes [nTPM]":"7.5","Single Cell Type RNA - B-cells [nTPM]":"25.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"25.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"22.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.0","Single Cell Type RNA - dendritic cells [nTPM]":"26.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"43.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"29.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"17.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.8","Single Cell Type RNA - Erythroid cells [nTPM]":"22.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"30.4","Single Cell Type RNA - Fibroblasts [nTPM]":"16.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.6","Single Cell Type RNA - granulocytes [nTPM]":"16.5","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"24.3","Single Cell Type RNA - Hepatocytes [nTPM]":"42.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.9","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"26.4","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.3","Single Cell Type RNA - Leydig cells [nTPM]":"17.4","Single Cell Type RNA - Macrophages [nTPM]":"25.8","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"43.7","Single Cell Type RNA - Muller glia cells [nTPM]":"18.4","Single Cell Type RNA - NK-cells [nTPM]":"32.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.2","Single Cell Type RNA - Paneth cells [nTPM]":"41.5","Single Cell Type RNA - Peritubular cells [nTPM]":"17.7","Single Cell Type RNA - Plasma cells [nTPM]":"27.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"44.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.0","Single Cell Type RNA - Spermatocytes [nTPM]":"8.2","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"44.6","Single Cell Type RNA - T-cells [nTPM]":"26.5","Single Cell Type RNA - Theca cells [nTPM]":"12.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.3","Single Cell Type RNA - Urothelial cells [nTPM]":"24.6"},{"Gene":"AREG","Gene synonym":["AREGB","SDGF"],"Ensembl":"ENSG00000109321","Gene description":"Amphiregulin","Uniprot":["P15514"],"Chromosome":"4","Position":"74445136-74455005","Protein class":["Cancer-related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Cytokine","Growth factor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"129.9","placenta":"328.8","urinary bladder":"145.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"1119.1","Basal prostatic cells":"1254.3","Macrophages":"1271.1","Paneth cells":"909.8","Urothelial cells":"2102.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"67.1"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"11","RNA blood cell specific nTPM":{"basophil":"11.0","eosinophil":"11.8","NK-cell":"3.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"granulocytes":"11.8","NK-cells":"3.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"379.0","HBEC3-KT":"648.1","hTCEpi":"644.0","hTERT-HME1":"1365.7","MCF7":"416.8"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"olfactory bulb":"1.2"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008720","CAB023519"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1520000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB023519":"AB_2060673","HPA008720":"AB_1844978"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.32e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Tissue RNA - adipose tissue [nTPM]":"48.1","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"36.7","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"129.9","Tissue RNA - breast [nTPM]":"61.6","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"19.2","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"18.7","Tissue RNA - duodenum [nTPM]":"3.3","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"43.4","Tissue RNA - fallopian tube [nTPM]":"13.2","Tissue RNA - gallbladder [nTPM]":"74.1","Tissue RNA - heart muscle [nTPM]":"20.5","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"4.0","Tissue RNA - lung [nTPM]":"36.1","Tissue RNA - lymph node [nTPM]":"1.9","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"12.4","Tissue RNA - pancreas [nTPM]":"4.5","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"328.8","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"6.5","Tissue RNA - rectum [nTPM]":"18.9","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"11.7","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"18.4","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"6.5","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"10.0","Tissue RNA - stomach 1 [nTPM]":"20.2","Tissue RNA - testis [nTPM]":"9.3","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"5.4","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"145.6","Tissue RNA - vagina [nTPM]":"13.8","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"107.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.9","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"5.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.9","Cell RNA - CACO-2 [nTPM]":"379.0","Cell RNA - CAPAN-2 [nTPM]":"59.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"17.4","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"648.1","Cell RNA - HBF TERT88 [nTPM]":"6.5","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"2.8","Cell RNA - Hep G2 [nTPM]":"18.0","Cell RNA - HHSteC [nTPM]":"191.9","Cell RNA - HL-60 [nTPM]":"2.3","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"5.9","Cell RNA - hTCEpi [nTPM]":"644.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.8","Cell RNA - hTERT-HME1 [nTPM]":"1365.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"1.6","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"14.4","Cell RNA - MCF7 [nTPM]":"416.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"78.6","Cell RNA - PC-3 [nTPM]":"42.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"36.4","Cell RNA - RT4 [nTPM]":"2.9","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"22.2","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.4","Cell RNA - T-47d [nTPM]":"11.6","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"15.3","Cell RNA - U-2197 [nTPM]":"5.3","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.7","Blood RNA - basophil [nTPM]":"11.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"11.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"3.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"670.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"198.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"301.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"190.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1119.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1254.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"73.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"303.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"801.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"460.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"62.9","Single Cell Type RNA - Club cells [nTPM]":"183.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.8","Single Cell Type RNA - dendritic cells [nTPM]":"836.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"878.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"61.8","Single Cell Type RNA - Early spermatids [nTPM]":"70.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"167.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.3","Single Cell Type RNA - Endothelial cells [nTPM]":"32.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"41.6","Single Cell Type RNA - Erythroid cells [nTPM]":"18.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"80.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"254.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"193.1","Single Cell Type RNA - granulocytes [nTPM]":"680.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"4.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"393.5","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"250.4","Single Cell Type RNA - Langerhans cells [nTPM]":"196.4","Single Cell Type RNA - Late spermatids [nTPM]":"12.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"1271.1","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"497.1","Single Cell Type RNA - Paneth cells [nTPM]":"909.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"352.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"115.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"55.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.2","Single Cell Type RNA - Spermatocytes [nTPM]":"68.3","Single Cell Type RNA - Spermatogonia [nTPM]":"51.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"194.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"342.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"473.6","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"308.9","Single Cell Type RNA - Urothelial cells [nTPM]":"2102.9"},{"Gene":"ARID1A","Gene synonym":["B120","BAF250","BAF250a","C10rf4","C1orf4","P270","SMARCF1"],"Ensembl":"ENSG00000117713","Gene description":"AT-rich interaction domain 1A","Uniprot":["O14497"],"Chromosome":"1","Position":"26693236-26782104","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005456","CAB016334"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016334":"AB_673396","HPA005456":"AB_1078205"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.18e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"16.3","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"22.7","Tissue RNA - basal ganglia [nTPM]":"9.4","Tissue RNA - bone marrow [nTPM]":"37.0","Tissue RNA - breast [nTPM]":"16.4","Tissue RNA - cerebellum [nTPM]":"12.9","Tissue RNA - cerebral cortex [nTPM]":"24.3","Tissue RNA - cervix [nTPM]":"16.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"18.0","Tissue RNA - duodenum [nTPM]":"15.4","Tissue RNA - endometrium 1 [nTPM]":"20.4","Tissue RNA - epididymis [nTPM]":"15.8","Tissue RNA - esophagus [nTPM]":"22.2","Tissue RNA - fallopian tube [nTPM]":"18.3","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"17.4","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"35.8","Tissue RNA - kidney [nTPM]":"13.3","Tissue RNA - liver [nTPM]":"16.8","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"25.8","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"23.2","Tissue RNA - parathyroid gland [nTPM]":"19.3","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"18.6","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"20.1","Tissue RNA - salivary gland [nTPM]":"19.3","Tissue RNA - seminal vesicle [nTPM]":"14.4","Tissue RNA - skeletal muscle [nTPM]":"21.6","Tissue RNA - skin 1 [nTPM]":"20.5","Tissue RNA - small intestine [nTPM]":"20.3","Tissue RNA - smooth muscle [nTPM]":"17.5","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"24.3","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"16.7","Tissue RNA - thalamus [nTPM]":"17.9","Tissue RNA - thymus [nTPM]":"46.4","Tissue RNA - thyroid gland [nTPM]":"22.6","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"23.7","Tissue RNA - urinary bladder [nTPM]":"18.4","Tissue RNA - vagina [nTPM]":"17.8","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"53.2","Cell RNA - A549 [nTPM]":"49.5","Cell RNA - AF22 [nTPM]":"68.6","Cell RNA - AN3-CA [nTPM]":"71.5","Cell RNA - ASC diff [nTPM]":"19.6","Cell RNA - ASC TERT1 [nTPM]":"18.5","Cell RNA - BEWO [nTPM]":"32.3","Cell RNA - BJ [nTPM]":"24.4","Cell RNA - BJ hTERT+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"32.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.0","Cell RNA - CACO-2 [nTPM]":"36.3","Cell RNA - CAPAN-2 [nTPM]":"34.1","Cell RNA - Daudi [nTPM]":"74.3","Cell RNA - EFO-21 [nTPM]":"20.7","Cell RNA - fHDF\/TERT166 [nTPM]":"31.8","Cell RNA - GAMG [nTPM]":"20.7","Cell RNA - HaCaT [nTPM]":"31.6","Cell RNA - HAP1 [nTPM]":"60.3","Cell RNA - HBEC3-KT [nTPM]":"26.9","Cell RNA - HBF TERT88 [nTPM]":"37.9","Cell RNA - HDLM-2 [nTPM]":"92.7","Cell RNA - HEK 293 [nTPM]":"22.6","Cell RNA - HEL [nTPM]":"63.6","Cell RNA - HeLa [nTPM]":"33.0","Cell RNA - Hep G2 [nTPM]":"24.7","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"95.2","Cell RNA - HMC-1 [nTPM]":"19.6","Cell RNA - HSkMC [nTPM]":"21.7","Cell RNA - hTCEpi [nTPM]":"18.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.7","Cell RNA - hTERT-HME1 [nTPM]":"27.5","Cell RNA - hTERT-RPE1 [nTPM]":"18.2","Cell RNA - HUVEC TERT2 [nTPM]":"28.6","Cell RNA - JURKAT [nTPM]":"52.5","Cell RNA - K-562 [nTPM]":"77.7","Cell RNA - Karpas-707 [nTPM]":"81.1","Cell RNA - LHCN-M2 [nTPM]":"21.5","Cell RNA - MCF7 [nTPM]":"25.1","Cell RNA - MOLT-4 [nTPM]":"80.1","Cell RNA - NB-4 [nTPM]":"36.8","Cell RNA - NTERA-2 [nTPM]":"72.4","Cell RNA - OE19 [nTPM]":"34.5","Cell RNA - PC-3 [nTPM]":"22.9","Cell RNA - REH [nTPM]":"82.2","Cell RNA - RH-30 [nTPM]":"45.3","Cell RNA - RPMI-8226 [nTPM]":"42.1","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"35.3","Cell RNA - SCLC-21H [nTPM]":"62.9","Cell RNA - SH-SY5Y [nTPM]":"50.7","Cell RNA - SiHa [nTPM]":"42.7","Cell RNA - SK-BR-3 [nTPM]":"35.7","Cell RNA - SK-MEL-30 [nTPM]":"29.0","Cell RNA - SuSa [nTPM]":"37.8","Cell RNA - T-47d [nTPM]":"10.6","Cell RNA - THP-1 [nTPM]":"53.4","Cell RNA - TIME [nTPM]":"50.6","Cell RNA - U-138 MG [nTPM]":"34.9","Cell RNA - U-2 OS [nTPM]":"33.5","Cell RNA - U-2197 [nTPM]":"32.4","Cell RNA - U-251 MG [nTPM]":"39.9","Cell RNA - U-266\/70 [nTPM]":"38.0","Cell RNA - U-266\/84 [nTPM]":"54.9","Cell RNA - U-698 [nTPM]":"34.1","Cell RNA - U-87 MG [nTPM]":"21.2","Cell RNA - U-937 [nTPM]":"59.8","Cell RNA - WM-115 [nTPM]":"31.5","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"3.3","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"2.4","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"9.4","Brain RNA - cerebellum [nTPM]":"12.9","Brain RNA - cerebral cortex [nTPM]":"24.3","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"35.8","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"17.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"49.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.4","Single Cell Type RNA - Astrocytes [nTPM]":"99.9","Single Cell Type RNA - B-cells [nTPM]":"66.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"90.0","Single Cell Type RNA - Bipolar cells [nTPM]":"68.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"77.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"61.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"33.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"35.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.5","Single Cell Type RNA - dendritic cells [nTPM]":"56.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"46.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"35.3","Single Cell Type RNA - Early spermatids [nTPM]":"23.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"59.3","Single Cell Type RNA - Endothelial cells [nTPM]":"46.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"47.5","Single Cell Type RNA - Erythroid cells [nTPM]":"56.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"47.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.2","Single Cell Type RNA - Fibroblasts [nTPM]":"35.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"35.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.3","Single Cell Type RNA - granulocytes [nTPM]":"61.2","Single Cell Type RNA - Granulosa cells [nTPM]":"68.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.6","Single Cell Type RNA - Hepatocytes [nTPM]":"65.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.0","Single Cell Type RNA - Horizontal cells [nTPM]":"74.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"50.2","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"89.0","Single Cell Type RNA - Langerhans cells [nTPM]":"47.5","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"38.5","Single Cell Type RNA - Macrophages [nTPM]":"73.2","Single Cell Type RNA - Melanocytes [nTPM]":"40.9","Single Cell Type RNA - Microglial cells [nTPM]":"89.9","Single Cell Type RNA - monocytes [nTPM]":"86.4","Single Cell Type RNA - Muller glia cells [nTPM]":"30.8","Single Cell Type RNA - NK-cells [nTPM]":"53.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"116.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.7","Single Cell Type RNA - Paneth cells [nTPM]":"36.4","Single Cell Type RNA - Peritubular cells [nTPM]":"41.8","Single Cell Type RNA - Plasma cells [nTPM]":"48.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"50.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"42.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"38.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"47.3","Single Cell Type RNA - Spermatocytes [nTPM]":"44.1","Single Cell Type RNA - Spermatogonia [nTPM]":"52.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"101.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"94.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"36.7","Single Cell Type RNA - T-cells [nTPM]":"57.0","Single Cell Type RNA - Theca cells [nTPM]":"45.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.1","Single Cell Type RNA - Urothelial cells [nTPM]":"43.2"},{"Gene":"ARID2","Gene synonym":["BAF200","DKFZp686G052","FLJ30619","KIAA1557"],"Ensembl":"ENSG00000189079","Gene description":"AT-rich interaction domain 2","Uniprot":["Q68CP9"],"Chromosome":"12","Position":"45729706-45908040","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"525.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA063044"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 29: Early spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA063044":"AB_2684929"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.02e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.4","Tissue RNA - adrenal gland [nTPM]":"5.2","Tissue RNA - amygdala [nTPM]":"4.6","Tissue RNA - appendix [nTPM]":"6.7","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"12.6","Tissue RNA - breast [nTPM]":"7.5","Tissue RNA - cerebellum [nTPM]":"13.8","Tissue RNA - cerebral cortex [nTPM]":"6.9","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"5.0","Tissue RNA - endometrium 1 [nTPM]":"6.9","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"6.4","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"6.0","Tissue RNA - hippocampal formation [nTPM]":"5.0","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"6.3","Tissue RNA - liver [nTPM]":"5.4","Tissue RNA - lung [nTPM]":"7.8","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"7.8","Tissue RNA - midbrain [nTPM]":"6.4","Tissue RNA - ovary [nTPM]":"8.3","Tissue RNA - pancreas [nTPM]":"7.2","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"6.0","Tissue RNA - retina [nTPM]":"13.2","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"10.0","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"6.0","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"6.2","Tissue RNA - testis [nTPM]":"26.1","Tissue RNA - thalamus [nTPM]":"6.2","Tissue RNA - thymus [nTPM]":"18.7","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"8.9","Tissue RNA - urinary bladder [nTPM]":"6.8","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"9.8","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"14.5","Cell RNA - AF22 [nTPM]":"25.3","Cell RNA - AN3-CA [nTPM]":"11.1","Cell RNA - ASC diff [nTPM]":"10.5","Cell RNA - ASC TERT1 [nTPM]":"7.3","Cell RNA - BEWO [nTPM]":"13.7","Cell RNA - BJ [nTPM]":"7.0","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.9","Cell RNA - CACO-2 [nTPM]":"20.7","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"19.8","Cell RNA - EFO-21 [nTPM]":"12.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.8","Cell RNA - GAMG [nTPM]":"7.0","Cell RNA - HaCaT [nTPM]":"12.1","Cell RNA - HAP1 [nTPM]":"20.6","Cell RNA - HBEC3-KT [nTPM]":"11.8","Cell RNA - HBF TERT88 [nTPM]":"13.6","Cell RNA - HDLM-2 [nTPM]":"8.8","Cell RNA - HEK 293 [nTPM]":"9.8","Cell RNA - HEL [nTPM]":"26.1","Cell RNA - HeLa [nTPM]":"15.9","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"7.2","Cell RNA - HL-60 [nTPM]":"20.7","Cell RNA - HMC-1 [nTPM]":"11.5","Cell RNA - HSkMC [nTPM]":"6.0","Cell RNA - hTCEpi [nTPM]":"8.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.1","Cell RNA - hTERT-HME1 [nTPM]":"19.1","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"10.0","Cell RNA - JURKAT [nTPM]":"29.1","Cell RNA - K-562 [nTPM]":"22.4","Cell RNA - Karpas-707 [nTPM]":"19.9","Cell RNA - LHCN-M2 [nTPM]":"8.6","Cell RNA - MCF7 [nTPM]":"13.4","Cell RNA - MOLT-4 [nTPM]":"29.9","Cell RNA - NB-4 [nTPM]":"14.7","Cell RNA - NTERA-2 [nTPM]":"15.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"22.9","Cell RNA - RH-30 [nTPM]":"18.0","Cell RNA - RPMI-8226 [nTPM]":"19.0","Cell RNA - RPTEC TERT1 [nTPM]":"9.1","Cell RNA - RT4 [nTPM]":"16.9","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"17.4","Cell RNA - SiHa [nTPM]":"11.4","Cell RNA - SK-BR-3 [nTPM]":"13.0","Cell RNA - SK-MEL-30 [nTPM]":"11.1","Cell RNA - SuSa [nTPM]":"14.5","Cell RNA - T-47d [nTPM]":"20.0","Cell RNA - THP-1 [nTPM]":"40.8","Cell RNA - TIME [nTPM]":"11.8","Cell RNA - U-138 MG [nTPM]":"10.3","Cell RNA - U-2 OS [nTPM]":"12.3","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"9.2","Cell RNA - U-266\/70 [nTPM]":"13.2","Cell RNA - U-266\/84 [nTPM]":"11.8","Cell RNA - U-698 [nTPM]":"53.6","Cell RNA - U-87 MG [nTPM]":"7.9","Cell RNA - U-937 [nTPM]":"53.2","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"9.4","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"2.7","Blood RNA - gdT-cell [nTPM]":"2.4","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"3.4","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"2.0","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"4.6","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"13.8","Brain RNA - cerebral cortex [nTPM]":"6.9","Brain RNA - hippocampal formation [nTPM]":"5.0","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"7.8","Brain RNA - midbrain [nTPM]":"6.4","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"6.0","Brain RNA - thalamus [nTPM]":"6.2","Brain RNA - white matter [nTPM]":"9.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"28.4","Single Cell Type RNA - Astrocytes [nTPM]":"110.4","Single Cell Type RNA - B-cells [nTPM]":"30.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"33.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Bipolar cells [nTPM]":"51.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"17.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"68.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.5","Single Cell Type RNA - dendritic cells [nTPM]":"49.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"21.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.2","Single Cell Type RNA - Early spermatids [nTPM]":"525.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.8","Single Cell Type RNA - Endothelial cells [nTPM]":"21.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"35.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"56.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.5","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.7","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"29.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.2","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"60.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.0","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"29.8","Single Cell Type RNA - Langerhans cells [nTPM]":"36.7","Single Cell Type RNA - Late spermatids [nTPM]":"149.3","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"25.6","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"128.4","Single Cell Type RNA - monocytes [nTPM]":"22.4","Single Cell Type RNA - Muller glia cells [nTPM]":"19.9","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"144.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"157.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"18.8","Single Cell Type RNA - Paneth cells [nTPM]":"24.6","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"33.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"66.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.2","Single Cell Type RNA - Spermatocytes [nTPM]":"80.2","Single Cell Type RNA - Spermatogonia [nTPM]":"17.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.4","Single Cell Type RNA - T-cells [nTPM]":"34.8","Single Cell Type RNA - Theca cells [nTPM]":"16.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.9","Single Cell Type RNA - Urothelial cells [nTPM]":"21.0"},{"Gene":"ASXL1","Gene synonym":["KIAA0978"],"Ensembl":"ENSG00000171456","Gene description":"ASXL transcriptional regulator 1","Uniprot":["Q8IXJ9"],"Chromosome":"20","Position":"32358330-32439319","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Repressor"],"Disease involvement":["Cancer-related genes","Craniosynostosis"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA064156"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA064156":"AB_2685200"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.86e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.16e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.6","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"13.4","Tissue RNA - appendix [nTPM]":"18.1","Tissue RNA - basal ganglia [nTPM]":"14.4","Tissue RNA - bone marrow [nTPM]":"36.9","Tissue RNA - breast [nTPM]":"30.5","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"14.4","Tissue RNA - cervix [nTPM]":"30.6","Tissue RNA - choroid plexus [nTPM]":"20.2","Tissue RNA - colon [nTPM]":"31.6","Tissue RNA - duodenum [nTPM]":"12.2","Tissue RNA - endometrium 1 [nTPM]":"26.8","Tissue RNA - epididymis [nTPM]":"15.6","Tissue RNA - esophagus [nTPM]":"17.2","Tissue RNA - fallopian tube [nTPM]":"28.6","Tissue RNA - gallbladder [nTPM]":"13.7","Tissue RNA - heart muscle [nTPM]":"21.8","Tissue RNA - hippocampal formation [nTPM]":"14.1","Tissue RNA - hypothalamus [nTPM]":"15.6","Tissue RNA - kidney [nTPM]":"28.7","Tissue RNA - liver [nTPM]":"32.8","Tissue RNA - lung [nTPM]":"36.0","Tissue RNA - lymph node [nTPM]":"24.0","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"32.3","Tissue RNA - pancreas [nTPM]":"32.9","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"19.2","Tissue RNA - placenta [nTPM]":"17.3","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"24.8","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"19.7","Tissue RNA - salivary gland [nTPM]":"21.0","Tissue RNA - seminal vesicle [nTPM]":"13.3","Tissue RNA - skeletal muscle [nTPM]":"30.1","Tissue RNA - skin 1 [nTPM]":"23.2","Tissue RNA - small intestine [nTPM]":"27.8","Tissue RNA - smooth muscle [nTPM]":"18.4","Tissue RNA - spinal cord [nTPM]":"13.8","Tissue RNA - spleen [nTPM]":"35.0","Tissue RNA - stomach 1 [nTPM]":"24.7","Tissue RNA - testis [nTPM]":"37.2","Tissue RNA - thalamus [nTPM]":"15.1","Tissue RNA - thymus [nTPM]":"27.4","Tissue RNA - thyroid gland [nTPM]":"32.0","Tissue RNA - tongue [nTPM]":"16.4","Tissue RNA - tonsil [nTPM]":"25.0","Tissue RNA - urinary bladder [nTPM]":"26.4","Tissue RNA - vagina [nTPM]":"24.2","Tissue RNA - white matter [nTPM]":"17.1","Cell RNA - A-431 [nTPM]":"59.2","Cell RNA - A549 [nTPM]":"33.6","Cell RNA - AF22 [nTPM]":"52.7","Cell RNA - AN3-CA [nTPM]":"28.2","Cell RNA - ASC diff [nTPM]":"23.6","Cell RNA - ASC TERT1 [nTPM]":"28.6","Cell RNA - BEWO [nTPM]":"45.6","Cell RNA - BJ [nTPM]":"35.4","Cell RNA - BJ hTERT+ [nTPM]":"33.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.6","Cell RNA - CACO-2 [nTPM]":"99.8","Cell RNA - CAPAN-2 [nTPM]":"35.2","Cell RNA - Daudi [nTPM]":"54.4","Cell RNA - EFO-21 [nTPM]":"24.5","Cell RNA - fHDF\/TERT166 [nTPM]":"47.3","Cell RNA - GAMG [nTPM]":"62.2","Cell RNA - HaCaT [nTPM]":"39.5","Cell RNA - HAP1 [nTPM]":"45.3","Cell RNA - HBEC3-KT [nTPM]":"37.8","Cell RNA - HBF TERT88 [nTPM]":"53.2","Cell RNA - HDLM-2 [nTPM]":"70.6","Cell RNA - HEK 293 [nTPM]":"24.1","Cell RNA - HEL [nTPM]":"88.9","Cell RNA - HeLa [nTPM]":"53.6","Cell RNA - Hep G2 [nTPM]":"55.7","Cell RNA - HHSteC [nTPM]":"21.6","Cell RNA - HL-60 [nTPM]":"38.5","Cell RNA - HMC-1 [nTPM]":"36.1","Cell RNA - HSkMC [nTPM]":"32.4","Cell RNA - hTCEpi [nTPM]":"25.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.1","Cell RNA - hTERT-HME1 [nTPM]":"35.6","Cell RNA - hTERT-RPE1 [nTPM]":"33.3","Cell RNA - HUVEC TERT2 [nTPM]":"37.4","Cell RNA - JURKAT [nTPM]":"45.3","Cell RNA - K-562 [nTPM]":"45.2","Cell RNA - Karpas-707 [nTPM]":"29.1","Cell RNA - LHCN-M2 [nTPM]":"31.9","Cell RNA - MCF7 [nTPM]":"18.4","Cell RNA - MOLT-4 [nTPM]":"51.7","Cell RNA - NB-4 [nTPM]":"30.3","Cell RNA - NTERA-2 [nTPM]":"12.9","Cell RNA - OE19 [nTPM]":"27.7","Cell RNA - PC-3 [nTPM]":"38.9","Cell RNA - REH [nTPM]":"30.8","Cell RNA - RH-30 [nTPM]":"62.1","Cell RNA - RPMI-8226 [nTPM]":"24.8","Cell RNA - RPTEC TERT1 [nTPM]":"27.1","Cell RNA - RT4 [nTPM]":"28.4","Cell RNA - SCLC-21H [nTPM]":"23.7","Cell RNA - SH-SY5Y [nTPM]":"38.2","Cell RNA - SiHa [nTPM]":"68.9","Cell RNA - SK-BR-3 [nTPM]":"23.5","Cell RNA - SK-MEL-30 [nTPM]":"31.7","Cell RNA - SuSa [nTPM]":"27.9","Cell RNA - T-47d [nTPM]":"32.7","Cell RNA - THP-1 [nTPM]":"27.0","Cell RNA - TIME [nTPM]":"39.9","Cell RNA - U-138 MG [nTPM]":"69.1","Cell RNA - U-2 OS [nTPM]":"59.4","Cell RNA - U-2197 [nTPM]":"32.3","Cell RNA - U-251 MG [nTPM]":"43.2","Cell RNA - U-266\/70 [nTPM]":"33.9","Cell RNA - U-266\/84 [nTPM]":"38.6","Cell RNA - U-698 [nTPM]":"39.3","Cell RNA - U-87 MG [nTPM]":"34.0","Cell RNA - U-937 [nTPM]":"100.2","Cell RNA - WM-115 [nTPM]":"27.8","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"2.5","Blood RNA - memory B-cell [nTPM]":"4.8","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"3.9","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"3.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.0","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"9.0","Blood RNA - total PBMC [nTPM]":"1.5","Brain RNA - amygdala [nTPM]":"13.4","Brain RNA - basal ganglia [nTPM]":"14.4","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"14.4","Brain RNA - hippocampal formation [nTPM]":"14.1","Brain RNA - hypothalamus [nTPM]":"15.6","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"13.8","Brain RNA - thalamus [nTPM]":"15.1","Brain RNA - white matter [nTPM]":"17.1","Single Cell Type RNA - Adipocytes [nTPM]":"92.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.5","Single Cell Type RNA - Astrocytes [nTPM]":"54.9","Single Cell Type RNA - B-cells [nTPM]":"63.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Bipolar cells [nTPM]":"21.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"52.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"48.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"17.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.0","Single Cell Type RNA - dendritic cells [nTPM]":"55.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"25.4","Single Cell Type RNA - Ductal cells [nTPM]":"13.5","Single Cell Type RNA - Early spermatids [nTPM]":"97.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"80.1","Single Cell Type RNA - Endothelial cells [nTPM]":"65.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"16.5","Single Cell Type RNA - Fibroblasts [nTPM]":"49.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"86.2","Single Cell Type RNA - granulocytes [nTPM]":"18.3","Single Cell Type RNA - Granulosa cells [nTPM]":"57.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.0","Single Cell Type RNA - Hepatocytes [nTPM]":"34.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"21.3","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"80.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.2","Single Cell Type RNA - Langerhans cells [nTPM]":"42.2","Single Cell Type RNA - Late spermatids [nTPM]":"84.9","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"33.5","Single Cell Type RNA - Melanocytes [nTPM]":"78.2","Single Cell Type RNA - Microglial cells [nTPM]":"75.9","Single Cell Type RNA - monocytes [nTPM]":"16.7","Single Cell Type RNA - Muller glia cells [nTPM]":"11.6","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"125.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.7","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"94.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"49.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"29.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"31.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"96.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"62.7","Single Cell Type RNA - Spermatocytes [nTPM]":"31.0","Single Cell Type RNA - Spermatogonia [nTPM]":"16.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"67.2","Single Cell Type RNA - Theca cells [nTPM]":"36.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.5","Single Cell Type RNA - Urothelial cells [nTPM]":"40.5"},{"Gene":"ATF1","Gene synonym":["TREB36"],"Ensembl":"ENSG00000123268","Gene description":"Activating transcription factor 1","Uniprot":["P18846"],"Chromosome":"12","Position":"50763710-50821162","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016222","HPA055069","HPA055406"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016222":"AB_2290030","HPA055069":"AB_2682688","HPA055406":"AB_2682807"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.17e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"21.2","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"15.8","Tissue RNA - basal ganglia [nTPM]":"5.1","Tissue RNA - bone marrow [nTPM]":"14.8","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"14.2","Tissue RNA - cerebral cortex [nTPM]":"7.1","Tissue RNA - cervix [nTPM]":"16.7","Tissue RNA - choroid plexus [nTPM]":"8.2","Tissue RNA - colon [nTPM]":"18.0","Tissue RNA - duodenum [nTPM]":"16.0","Tissue RNA - endometrium 1 [nTPM]":"18.2","Tissue RNA - epididymis [nTPM]":"13.7","Tissue RNA - esophagus [nTPM]":"17.0","Tissue RNA - fallopian tube [nTPM]":"17.8","Tissue RNA - gallbladder [nTPM]":"16.5","Tissue RNA - heart muscle [nTPM]":"14.6","Tissue RNA - hippocampal formation [nTPM]":"4.8","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"17.4","Tissue RNA - liver [nTPM]":"20.8","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"21.5","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"23.1","Tissue RNA - pancreas [nTPM]":"9.1","Tissue RNA - parathyroid gland [nTPM]":"19.8","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"16.7","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"18.6","Tissue RNA - retina [nTPM]":"11.9","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"13.5","Tissue RNA - skeletal muscle [nTPM]":"32.4","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"16.7","Tissue RNA - spinal cord [nTPM]":"5.4","Tissue RNA - spleen [nTPM]":"17.9","Tissue RNA - stomach 1 [nTPM]":"14.3","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"6.6","Tissue RNA - thymus [nTPM]":"29.2","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"23.7","Tissue RNA - tonsil [nTPM]":"21.5","Tissue RNA - urinary bladder [nTPM]":"16.5","Tissue RNA - vagina [nTPM]":"12.9","Tissue RNA - white matter [nTPM]":"6.9","Cell RNA - A-431 [nTPM]":"28.6","Cell RNA - A549 [nTPM]":"20.4","Cell RNA - AF22 [nTPM]":"21.0","Cell RNA - AN3-CA [nTPM]":"21.4","Cell RNA - ASC diff [nTPM]":"29.0","Cell RNA - ASC TERT1 [nTPM]":"30.4","Cell RNA - BEWO [nTPM]":"52.2","Cell RNA - BJ [nTPM]":"29.5","Cell RNA - BJ hTERT+ [nTPM]":"50.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"45.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.8","Cell RNA - CACO-2 [nTPM]":"41.7","Cell RNA - CAPAN-2 [nTPM]":"43.7","Cell RNA - Daudi [nTPM]":"38.7","Cell RNA - EFO-21 [nTPM]":"47.6","Cell RNA - fHDF\/TERT166 [nTPM]":"34.5","Cell RNA - GAMG [nTPM]":"20.0","Cell RNA - HaCaT [nTPM]":"22.8","Cell RNA - HAP1 [nTPM]":"24.9","Cell RNA - HBEC3-KT [nTPM]":"30.6","Cell RNA - HBF TERT88 [nTPM]":"47.6","Cell RNA - HDLM-2 [nTPM]":"39.0","Cell RNA - HEK 293 [nTPM]":"25.8","Cell RNA - HEL [nTPM]":"42.8","Cell RNA - HeLa [nTPM]":"43.1","Cell RNA - Hep G2 [nTPM]":"22.6","Cell RNA - HHSteC [nTPM]":"56.5","Cell RNA - HL-60 [nTPM]":"62.3","Cell RNA - HMC-1 [nTPM]":"39.6","Cell RNA - HSkMC [nTPM]":"33.7","Cell RNA - hTCEpi [nTPM]":"45.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.8","Cell RNA - hTERT-HME1 [nTPM]":"52.8","Cell RNA - hTERT-RPE1 [nTPM]":"47.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.5","Cell RNA - JURKAT [nTPM]":"27.1","Cell RNA - K-562 [nTPM]":"53.2","Cell RNA - Karpas-707 [nTPM]":"36.2","Cell RNA - LHCN-M2 [nTPM]":"33.9","Cell RNA - MCF7 [nTPM]":"42.4","Cell RNA - MOLT-4 [nTPM]":"39.6","Cell RNA - NB-4 [nTPM]":"37.3","Cell RNA - NTERA-2 [nTPM]":"30.0","Cell RNA - OE19 [nTPM]":"33.0","Cell RNA - PC-3 [nTPM]":"32.1","Cell RNA - REH [nTPM]":"37.5","Cell RNA - RH-30 [nTPM]":"32.3","Cell RNA - RPMI-8226 [nTPM]":"45.9","Cell RNA - RPTEC TERT1 [nTPM]":"33.6","Cell RNA - RT4 [nTPM]":"19.5","Cell RNA - SCLC-21H [nTPM]":"27.9","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"61.8","Cell RNA - SK-BR-3 [nTPM]":"26.5","Cell RNA - SK-MEL-30 [nTPM]":"44.7","Cell RNA - SuSa [nTPM]":"28.5","Cell RNA - T-47d [nTPM]":"37.3","Cell RNA - THP-1 [nTPM]":"37.6","Cell RNA - TIME [nTPM]":"16.1","Cell RNA - U-138 MG [nTPM]":"32.1","Cell RNA - U-2 OS [nTPM]":"38.2","Cell RNA - U-2197 [nTPM]":"26.4","Cell RNA - U-251 MG [nTPM]":"24.1","Cell RNA - U-266\/70 [nTPM]":"20.2","Cell RNA - U-266\/84 [nTPM]":"25.8","Cell RNA - U-698 [nTPM]":"63.6","Cell RNA - U-87 MG [nTPM]":"30.9","Cell RNA - U-937 [nTPM]":"33.9","Cell RNA - WM-115 [nTPM]":"15.3","Blood RNA - basophil [nTPM]":"6.6","Blood RNA - classical monocyte [nTPM]":"17.9","Blood RNA - eosinophil [nTPM]":"42.7","Blood RNA - gdT-cell [nTPM]":"20.2","Blood RNA - intermediate monocyte [nTPM]":"18.8","Blood RNA - MAIT T-cell [nTPM]":"23.1","Blood RNA - memory B-cell [nTPM]":"20.2","Blood RNA - memory CD4 T-cell [nTPM]":"21.7","Blood RNA - memory CD8 T-cell [nTPM]":"24.1","Blood RNA - myeloid DC [nTPM]":"21.1","Blood RNA - naive B-cell [nTPM]":"21.7","Blood RNA - naive CD4 T-cell [nTPM]":"26.4","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"11.2","Blood RNA - NK-cell [nTPM]":"20.8","Blood RNA - non-classical monocyte [nTPM]":"12.7","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"28.8","Blood RNA - total PBMC [nTPM]":"19.1","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"5.1","Brain RNA - cerebellum [nTPM]":"14.2","Brain RNA - cerebral cortex [nTPM]":"7.1","Brain RNA - hippocampal formation [nTPM]":"4.8","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"5.4","Brain RNA - thalamus [nTPM]":"6.6","Brain RNA - white matter [nTPM]":"6.9","Single Cell Type RNA - Adipocytes [nTPM]":"25.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.5","Single Cell Type RNA - Astrocytes [nTPM]":"22.2","Single Cell Type RNA - B-cells [nTPM]":"41.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"75.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"12.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"26.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.6","Single Cell Type RNA - dendritic cells [nTPM]":"25.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.9","Single Cell Type RNA - Early spermatids [nTPM]":"9.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.8","Single Cell Type RNA - Endothelial cells [nTPM]":"23.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"46.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"77.1","Single Cell Type RNA - Fibroblasts [nTPM]":"33.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.0","Single Cell Type RNA - granulocytes [nTPM]":"10.1","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"16.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"27.5","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"29.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.7","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"25.2","Single Cell Type RNA - Langerhans cells [nTPM]":"48.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"32.0","Single Cell Type RNA - Macrophages [nTPM]":"24.2","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"24.6","Single Cell Type RNA - Muller glia cells [nTPM]":"14.2","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.8","Single Cell Type RNA - Paneth cells [nTPM]":"17.9","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"34.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"34.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.7","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"10.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"80.6","Single Cell Type RNA - T-cells [nTPM]":"38.4","Single Cell Type RNA - Theca cells [nTPM]":"20.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.8","Single Cell Type RNA - Urothelial cells [nTPM]":"36.9"},{"Gene":"ATM","Gene synonym":["ATA","ATC","ATD","ATDC","TEL1","TELO1"],"Ensembl":"ENSG00000149311","Gene description":"ATM serine\/threonine kinase","Uniprot":["Q13315"],"Chromosome":"11","Position":"108222832-108369102","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Neurodegeneration","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"210.6","NK-cells":"339.8","Oligodendrocytes":"217.6","Rod photoreceptor cells":"200.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-698":"78.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000102","HPA067142"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB000102":null,"HPA067142":"AB_2685789"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.2","Tissue RNA - adrenal gland [nTPM]":"7.4","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"17.5","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"16.2","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"17.0","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"16.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.2","Tissue RNA - endometrium 1 [nTPM]":"10.0","Tissue RNA - epididymis [nTPM]":"9.9","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"7.3","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"5.8","Tissue RNA - liver [nTPM]":"7.8","Tissue RNA - lung [nTPM]":"7.6","Tissue RNA - lymph node [nTPM]":"33.7","Tissue RNA - medulla oblongata [nTPM]":"15.8","Tissue RNA - midbrain [nTPM]":"13.1","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"14.8","Tissue RNA - parathyroid gland [nTPM]":"9.3","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"8.0","Tissue RNA - pons [nTPM]":"17.0","Tissue RNA - prostate [nTPM]":"6.3","Tissue RNA - rectum [nTPM]":"7.0","Tissue RNA - retina [nTPM]":"20.6","Tissue RNA - salivary gland [nTPM]":"11.4","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"4.4","Tissue RNA - skin 1 [nTPM]":"7.5","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"6.9","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"22.2","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"18.2","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"6.0","Tissue RNA - tonsil [nTPM]":"25.9","Tissue RNA - urinary bladder [nTPM]":"7.1","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"28.8","Cell RNA - A-431 [nTPM]":"4.3","Cell RNA - A549 [nTPM]":"6.8","Cell RNA - AF22 [nTPM]":"14.8","Cell RNA - AN3-CA [nTPM]":"7.6","Cell RNA - ASC diff [nTPM]":"20.2","Cell RNA - ASC TERT1 [nTPM]":"29.1","Cell RNA - BEWO [nTPM]":"3.1","Cell RNA - BJ [nTPM]":"10.9","Cell RNA - BJ hTERT+ [nTPM]":"13.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"7.1","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"10.2","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"11.6","Cell RNA - HBEC3-KT [nTPM]":"10.8","Cell RNA - HBF TERT88 [nTPM]":"9.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"5.7","Cell RNA - HEL [nTPM]":"15.2","Cell RNA - HeLa [nTPM]":"8.7","Cell RNA - Hep G2 [nTPM]":"10.2","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"16.4","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"18.3","Cell RNA - hTCEpi [nTPM]":"6.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"21.2","Cell RNA - hTERT-RPE1 [nTPM]":"15.2","Cell RNA - HUVEC TERT2 [nTPM]":"14.1","Cell RNA - JURKAT [nTPM]":"16.5","Cell RNA - K-562 [nTPM]":"12.4","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"14.3","Cell RNA - MCF7 [nTPM]":"3.4","Cell RNA - MOLT-4 [nTPM]":"10.6","Cell RNA - NB-4 [nTPM]":"18.5","Cell RNA - NTERA-2 [nTPM]":"9.8","Cell RNA - OE19 [nTPM]":"8.6","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"9.7","Cell RNA - RH-30 [nTPM]":"9.7","Cell RNA - RPMI-8226 [nTPM]":"24.9","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"7.5","Cell RNA - SCLC-21H [nTPM]":"9.0","Cell RNA - SH-SY5Y [nTPM]":"10.5","Cell RNA - SiHa [nTPM]":"11.1","Cell RNA - SK-BR-3 [nTPM]":"4.7","Cell RNA - SK-MEL-30 [nTPM]":"20.6","Cell RNA - SuSa [nTPM]":"13.2","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"10.1","Cell RNA - TIME [nTPM]":"23.7","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"8.4","Cell RNA - U-2197 [nTPM]":"7.3","Cell RNA - U-251 MG [nTPM]":"9.0","Cell RNA - U-266\/70 [nTPM]":"6.2","Cell RNA - U-266\/84 [nTPM]":"7.0","Cell RNA - U-698 [nTPM]":"78.3","Cell RNA - U-87 MG [nTPM]":"7.0","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"18.8","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"5.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"16.5","Blood RNA - intermediate monocyte [nTPM]":"5.7","Blood RNA - MAIT T-cell [nTPM]":"11.1","Blood RNA - memory B-cell [nTPM]":"11.6","Blood RNA - memory CD4 T-cell [nTPM]":"11.7","Blood RNA - memory CD8 T-cell [nTPM]":"12.5","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"13.0","Blood RNA - naive CD4 T-cell [nTPM]":"21.1","Blood RNA - naive CD8 T-cell [nTPM]":"20.4","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"9.7","Blood RNA - non-classical monocyte [nTPM]":"13.3","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"6.1","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"17.0","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"7.3","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"15.8","Brain RNA - midbrain [nTPM]":"13.1","Brain RNA - pons [nTPM]":"17.0","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"28.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"62.7","Single Cell Type RNA - B-cells [nTPM]":"146.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Bipolar cells [nTPM]":"111.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"19.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"210.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.9","Single Cell Type RNA - dendritic cells [nTPM]":"140.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.9","Single Cell Type RNA - Early spermatids [nTPM]":"19.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"52.1","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.4","Single Cell Type RNA - Erythroid cells [nTPM]":"39.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"70.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.2","Single Cell Type RNA - Fibroblasts [nTPM]":"39.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.9","Single Cell Type RNA - granulocytes [nTPM]":"13.3","Single Cell Type RNA - Granulosa cells [nTPM]":"45.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"23.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.1","Single Cell Type RNA - Horizontal cells [nTPM]":"60.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"96.4","Single Cell Type RNA - Langerhans cells [nTPM]":"34.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"69.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"178.9","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"27.3","Single Cell Type RNA - NK-cells [nTPM]":"339.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"85.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"217.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.6","Single Cell Type RNA - Paneth cells [nTPM]":"7.6","Single Cell Type RNA - Peritubular cells [nTPM]":"27.8","Single Cell Type RNA - Plasma cells [nTPM]":"96.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"9.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"200.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"41.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.2","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"37.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"147.7","Single Cell Type RNA - Theca cells [nTPM]":"52.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"ATR","Gene synonym":["FRP1","MEC1","SCKL","SCKL1"],"Ensembl":"ENSG00000175054","Gene description":"ATR serine\/threonine kinase","Uniprot":["Q13535"],"Chromosome":"3","Position":"142449007-142578733","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"93.0","Inhibitory neurons":"94.4","Microglial cells":"73.1","Oligodendrocyte precursor cells":"65.4","Oligodendrocytes":"71.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054320"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA054320":"AB_2682448"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.90e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.23e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"4.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"3.2","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"3.8","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"2.7","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"3.1","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"3.6","Tissue RNA - lung [nTPM]":"2.9","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"1.5","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"3.1","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"3.0","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"2.9","Tissue RNA - salivary gland [nTPM]":"3.5","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"2.7","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"3.2","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"1.2","Tissue RNA - thymus [nTPM]":"4.9","Tissue RNA - thyroid gland [nTPM]":"5.0","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"4.6","Tissue RNA - urinary bladder [nTPM]":"4.1","Tissue RNA - vagina [nTPM]":"2.7","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"28.6","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"7.1","Cell RNA - AN3-CA [nTPM]":"7.0","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"13.6","Cell RNA - BEWO [nTPM]":"8.8","Cell RNA - BJ [nTPM]":"14.8","Cell RNA - BJ hTERT+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.7","Cell RNA - CACO-2 [nTPM]":"6.4","Cell RNA - CAPAN-2 [nTPM]":"6.8","Cell RNA - Daudi [nTPM]":"19.9","Cell RNA - EFO-21 [nTPM]":"14.6","Cell RNA - fHDF\/TERT166 [nTPM]":"10.1","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"16.1","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"12.8","Cell RNA - HBF TERT88 [nTPM]":"15.0","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"7.9","Cell RNA - HEL [nTPM]":"11.9","Cell RNA - HeLa [nTPM]":"8.2","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"4.2","Cell RNA - HL-60 [nTPM]":"20.5","Cell RNA - HMC-1 [nTPM]":"5.3","Cell RNA - HSkMC [nTPM]":"9.8","Cell RNA - hTCEpi [nTPM]":"4.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.5","Cell RNA - hTERT-HME1 [nTPM]":"10.3","Cell RNA - hTERT-RPE1 [nTPM]":"5.8","Cell RNA - HUVEC TERT2 [nTPM]":"11.6","Cell RNA - JURKAT [nTPM]":"8.7","Cell RNA - K-562 [nTPM]":"8.2","Cell RNA - Karpas-707 [nTPM]":"7.5","Cell RNA - LHCN-M2 [nTPM]":"9.6","Cell RNA - MCF7 [nTPM]":"7.5","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"2.6","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"15.6","Cell RNA - PC-3 [nTPM]":"9.6","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"12.5","Cell RNA - RPMI-8226 [nTPM]":"13.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.3","Cell RNA - RT4 [nTPM]":"11.1","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"5.1","Cell RNA - SiHa [nTPM]":"28.6","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"8.0","Cell RNA - SuSa [nTPM]":"7.8","Cell RNA - T-47d [nTPM]":"12.0","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"14.6","Cell RNA - U-138 MG [nTPM]":"10.5","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"12.3","Cell RNA - U-251 MG [nTPM]":"15.2","Cell RNA - U-266\/70 [nTPM]":"10.8","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"18.5","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"6.5","Cell RNA - WM-115 [nTPM]":"8.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"1.5","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.2","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"11.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"22.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"14.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"37.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.9","Single Cell Type RNA - Early spermatids [nTPM]":"16.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.6","Single Cell Type RNA - Endothelial cells [nTPM]":"10.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"14.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"93.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.6","Single Cell Type RNA - Fibroblasts [nTPM]":"8.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"16.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"7.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"94.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.8","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"8.7","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"12.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"73.1","Single Cell Type RNA - monocytes [nTPM]":"12.0","Single Cell Type RNA - Muller glia cells [nTPM]":"6.0","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"65.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"71.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.4","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"23.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"23.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.8","Single Cell Type RNA - Spermatocytes [nTPM]":"50.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"15.1","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"6.1"},{"Gene":"ATRX","Gene synonym":["JMS","MRX52","RAD54","XH2","XNP"],"Ensembl":"ENSG00000085224","Gene description":"ATRX chromatin remodeler","Uniprot":["P46100"],"Chromosome":"X","Position":"77504880-77786233","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["DNA damage","DNA repair","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Helicase","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001906","CAB009372","HPA064684","CAB068176"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB009372":"AB_2061023","CAB068176":"AB_2665665","HPA001906":"AB_1078249","HPA064684":"AB_2685321"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.69e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.0","Tissue RNA - adrenal gland [nTPM]":"15.9","Tissue RNA - amygdala [nTPM]":"17.3","Tissue RNA - appendix [nTPM]":"17.6","Tissue RNA - basal ganglia [nTPM]":"20.4","Tissue RNA - bone marrow [nTPM]":"29.9","Tissue RNA - breast [nTPM]":"18.1","Tissue RNA - cerebellum [nTPM]":"32.9","Tissue RNA - cerebral cortex [nTPM]":"20.4","Tissue RNA - cervix [nTPM]":"18.0","Tissue RNA - choroid plexus [nTPM]":"21.4","Tissue RNA - colon [nTPM]":"12.7","Tissue RNA - duodenum [nTPM]":"11.2","Tissue RNA - endometrium 1 [nTPM]":"21.2","Tissue RNA - epididymis [nTPM]":"14.8","Tissue RNA - esophagus [nTPM]":"13.3","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"14.7","Tissue RNA - heart muscle [nTPM]":"15.5","Tissue RNA - hippocampal formation [nTPM]":"19.2","Tissue RNA - hypothalamus [nTPM]":"19.8","Tissue RNA - kidney [nTPM]":"16.9","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"13.4","Tissue RNA - lymph node [nTPM]":"22.6","Tissue RNA - medulla oblongata [nTPM]":"15.0","Tissue RNA - midbrain [nTPM]":"20.1","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"13.4","Tissue RNA - parathyroid gland [nTPM]":"23.2","Tissue RNA - pituitary gland [nTPM]":"8.5","Tissue RNA - placenta [nTPM]":"16.6","Tissue RNA - pons [nTPM]":"16.6","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"13.5","Tissue RNA - retina [nTPM]":"26.8","Tissue RNA - salivary gland [nTPM]":"14.0","Tissue RNA - seminal vesicle [nTPM]":"14.8","Tissue RNA - skeletal muscle [nTPM]":"19.1","Tissue RNA - skin 1 [nTPM]":"15.6","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"15.6","Tissue RNA - spinal cord [nTPM]":"16.4","Tissue RNA - spleen [nTPM]":"22.8","Tissue RNA - stomach 1 [nTPM]":"16.5","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"22.6","Tissue RNA - thymus [nTPM]":"25.7","Tissue RNA - thyroid gland [nTPM]":"20.0","Tissue RNA - tongue [nTPM]":"26.9","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"14.1","Tissue RNA - vagina [nTPM]":"9.9","Tissue RNA - white matter [nTPM]":"19.7","Cell RNA - A-431 [nTPM]":"36.0","Cell RNA - A549 [nTPM]":"55.1","Cell RNA - AF22 [nTPM]":"60.1","Cell RNA - AN3-CA [nTPM]":"45.0","Cell RNA - ASC diff [nTPM]":"31.8","Cell RNA - ASC TERT1 [nTPM]":"38.1","Cell RNA - BEWO [nTPM]":"21.2","Cell RNA - BJ [nTPM]":"29.4","Cell RNA - BJ hTERT+ [nTPM]":"27.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.9","Cell RNA - CACO-2 [nTPM]":"19.6","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"48.5","Cell RNA - EFO-21 [nTPM]":"29.9","Cell RNA - fHDF\/TERT166 [nTPM]":"32.5","Cell RNA - GAMG [nTPM]":"39.9","Cell RNA - HaCaT [nTPM]":"30.0","Cell RNA - HAP1 [nTPM]":"44.6","Cell RNA - HBEC3-KT [nTPM]":"18.1","Cell RNA - HBF TERT88 [nTPM]":"37.5","Cell RNA - HDLM-2 [nTPM]":"27.3","Cell RNA - HEK 293 [nTPM]":"30.8","Cell RNA - HEL [nTPM]":"29.3","Cell RNA - HeLa [nTPM]":"67.2","Cell RNA - Hep G2 [nTPM]":"16.2","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"38.4","Cell RNA - HMC-1 [nTPM]":"10.2","Cell RNA - HSkMC [nTPM]":"25.5","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.2","Cell RNA - hTERT-HME1 [nTPM]":"30.4","Cell RNA - hTERT-RPE1 [nTPM]":"29.4","Cell RNA - HUVEC TERT2 [nTPM]":"41.9","Cell RNA - JURKAT [nTPM]":"30.3","Cell RNA - K-562 [nTPM]":"34.9","Cell RNA - Karpas-707 [nTPM]":"53.3","Cell RNA - LHCN-M2 [nTPM]":"29.3","Cell RNA - MCF7 [nTPM]":"27.6","Cell RNA - MOLT-4 [nTPM]":"30.2","Cell RNA - NB-4 [nTPM]":"25.0","Cell RNA - NTERA-2 [nTPM]":"42.0","Cell RNA - OE19 [nTPM]":"17.6","Cell RNA - PC-3 [nTPM]":"42.5","Cell RNA - REH [nTPM]":"48.6","Cell RNA - RH-30 [nTPM]":"76.3","Cell RNA - RPMI-8226 [nTPM]":"26.0","Cell RNA - RPTEC TERT1 [nTPM]":"25.6","Cell RNA - RT4 [nTPM]":"46.4","Cell RNA - SCLC-21H [nTPM]":"33.1","Cell RNA - SH-SY5Y [nTPM]":"55.5","Cell RNA - SiHa [nTPM]":"60.5","Cell RNA - SK-BR-3 [nTPM]":"23.1","Cell RNA - SK-MEL-30 [nTPM]":"21.9","Cell RNA - SuSa [nTPM]":"37.2","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"20.8","Cell RNA - TIME [nTPM]":"55.8","Cell RNA - U-138 MG [nTPM]":"32.8","Cell RNA - U-2 OS [nTPM]":"76.1","Cell RNA - U-2197 [nTPM]":"34.4","Cell RNA - U-251 MG [nTPM]":"21.0","Cell RNA - U-266\/70 [nTPM]":"16.3","Cell RNA - U-266\/84 [nTPM]":"52.9","Cell RNA - U-698 [nTPM]":"42.1","Cell RNA - U-87 MG [nTPM]":"23.0","Cell RNA - U-937 [nTPM]":"30.9","Cell RNA - WM-115 [nTPM]":"27.8","Blood RNA - basophil [nTPM]":"44.0","Blood RNA - classical monocyte [nTPM]":"10.5","Blood RNA - eosinophil [nTPM]":"22.7","Blood RNA - gdT-cell [nTPM]":"26.0","Blood RNA - intermediate monocyte [nTPM]":"13.3","Blood RNA - MAIT T-cell [nTPM]":"25.2","Blood RNA - memory B-cell [nTPM]":"31.2","Blood RNA - memory CD4 T-cell [nTPM]":"24.0","Blood RNA - memory CD8 T-cell [nTPM]":"20.9","Blood RNA - myeloid DC [nTPM]":"8.1","Blood RNA - naive B-cell [nTPM]":"32.4","Blood RNA - naive CD4 T-cell [nTPM]":"24.6","Blood RNA - naive CD8 T-cell [nTPM]":"20.1","Blood RNA - neutrophil [nTPM]":"33.2","Blood RNA - NK-cell [nTPM]":"23.2","Blood RNA - non-classical monocyte [nTPM]":"20.0","Blood RNA - plasmacytoid DC [nTPM]":"20.7","Blood RNA - T-reg [nTPM]":"22.2","Blood RNA - total PBMC [nTPM]":"9.7","Brain RNA - amygdala [nTPM]":"17.3","Brain RNA - basal ganglia [nTPM]":"20.4","Brain RNA - cerebellum [nTPM]":"32.9","Brain RNA - cerebral cortex [nTPM]":"20.4","Brain RNA - hippocampal formation [nTPM]":"19.2","Brain RNA - hypothalamus [nTPM]":"19.8","Brain RNA - medulla oblongata [nTPM]":"15.0","Brain RNA - midbrain [nTPM]":"20.1","Brain RNA - pons [nTPM]":"16.6","Brain RNA - spinal cord [nTPM]":"16.4","Brain RNA - thalamus [nTPM]":"22.6","Brain RNA - white matter [nTPM]":"19.7","Single Cell Type RNA - Adipocytes [nTPM]":"201.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"160.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"230.1","Single Cell Type RNA - Astrocytes [nTPM]":"157.4","Single Cell Type RNA - B-cells [nTPM]":"176.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"92.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"112.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"71.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"114.9","Single Cell Type RNA - Bipolar cells [nTPM]":"220.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"87.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"86.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"277.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"60.1","Single Cell Type RNA - Club cells [nTPM]":"101.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"71.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"212.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"72.2","Single Cell Type RNA - dendritic cells [nTPM]":"176.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"91.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"103.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"195.5","Single Cell Type RNA - Endothelial cells [nTPM]":"162.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"126.8","Single Cell Type RNA - Erythroid cells [nTPM]":"105.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"197.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"83.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.0","Single Cell Type RNA - Fibroblasts [nTPM]":"134.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"114.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"137.3","Single Cell Type RNA - granulocytes [nTPM]":"113.1","Single Cell Type RNA - Granulosa cells [nTPM]":"261.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"97.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"70.9","Single Cell Type RNA - Horizontal cells [nTPM]":"158.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"246.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.0","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"87.0","Single Cell Type RNA - Langerhans cells [nTPM]":"101.6","Single Cell Type RNA - Late spermatids [nTPM]":"12.7","Single Cell Type RNA - Leydig cells [nTPM]":"162.4","Single Cell Type RNA - Macrophages [nTPM]":"113.1","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"195.8","Single Cell Type RNA - monocytes [nTPM]":"149.0","Single Cell Type RNA - Muller glia cells [nTPM]":"112.3","Single Cell Type RNA - NK-cells [nTPM]":"183.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"202.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"237.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"92.0","Single Cell Type RNA - Paneth cells [nTPM]":"47.6","Single Cell Type RNA - Peritubular cells [nTPM]":"208.0","Single Cell Type RNA - Plasma cells [nTPM]":"183.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"120.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"102.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"245.4","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"174.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"160.0","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"52.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"78.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"84.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"59.8","Single Cell Type RNA - T-cells [nTPM]":"158.0","Single Cell Type RNA - Theca cells [nTPM]":"312.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"73.3","Single Cell Type RNA - Urothelial cells [nTPM]":"112.0"},{"Gene":"AXIN1","Gene synonym":["PPP1R49"],"Ensembl":"ENSG00000103126","Gene description":"Axin 1","Uniprot":["O15169"],"Chromosome":"16","Position":"287440-352723","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012987"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":["Nucleoli","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB012987":"AB_2533178"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.64e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.38e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"9.3","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"14.8","Tissue RNA - cerebral cortex [nTPM]":"12.5","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"17.1","Tissue RNA - duodenum [nTPM]":"12.3","Tissue RNA - endometrium 1 [nTPM]":"13.2","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"6.2","Tissue RNA - heart muscle [nTPM]":"11.6","Tissue RNA - hippocampal formation [nTPM]":"10.0","Tissue RNA - hypothalamus [nTPM]":"9.2","Tissue RNA - kidney [nTPM]":"11.6","Tissue RNA - liver [nTPM]":"11.2","Tissue RNA - lung [nTPM]":"13.7","Tissue RNA - lymph node [nTPM]":"10.5","Tissue RNA - medulla oblongata [nTPM]":"10.2","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"13.8","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"7.2","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"12.9","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"2.6","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"6.0","Tissue RNA - skeletal muscle [nTPM]":"21.1","Tissue RNA - skin 1 [nTPM]":"20.1","Tissue RNA - small intestine [nTPM]":"15.0","Tissue RNA - smooth muscle [nTPM]":"5.4","Tissue RNA - spinal cord [nTPM]":"9.2","Tissue RNA - spleen [nTPM]":"15.0","Tissue RNA - stomach 1 [nTPM]":"12.9","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"10.1","Tissue RNA - thymus [nTPM]":"12.5","Tissue RNA - thyroid gland [nTPM]":"11.9","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"6.6","Tissue RNA - urinary bladder [nTPM]":"14.5","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"18.1","Cell RNA - A549 [nTPM]":"25.6","Cell RNA - AF22 [nTPM]":"13.4","Cell RNA - AN3-CA [nTPM]":"23.7","Cell RNA - ASC diff [nTPM]":"9.8","Cell RNA - ASC TERT1 [nTPM]":"9.0","Cell RNA - BEWO [nTPM]":"28.0","Cell RNA - BJ [nTPM]":"11.9","Cell RNA - BJ hTERT+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.8","Cell RNA - CACO-2 [nTPM]":"37.9","Cell RNA - CAPAN-2 [nTPM]":"20.4","Cell RNA - Daudi [nTPM]":"27.7","Cell RNA - EFO-21 [nTPM]":"18.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.3","Cell RNA - GAMG [nTPM]":"19.4","Cell RNA - HaCaT [nTPM]":"25.4","Cell RNA - HAP1 [nTPM]":"21.1","Cell RNA - HBEC3-KT [nTPM]":"18.5","Cell RNA - HBF TERT88 [nTPM]":"7.2","Cell RNA - HDLM-2 [nTPM]":"27.5","Cell RNA - HEK 293 [nTPM]":"34.6","Cell RNA - HEL [nTPM]":"18.0","Cell RNA - HeLa [nTPM]":"21.9","Cell RNA - Hep G2 [nTPM]":"27.6","Cell RNA - HHSteC [nTPM]":"16.6","Cell RNA - HL-60 [nTPM]":"20.9","Cell RNA - HMC-1 [nTPM]":"19.3","Cell RNA - HSkMC [nTPM]":"9.0","Cell RNA - hTCEpi [nTPM]":"31.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.6","Cell RNA - hTERT-HME1 [nTPM]":"20.3","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"19.8","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"7.4","Cell RNA - MCF7 [nTPM]":"48.1","Cell RNA - MOLT-4 [nTPM]":"22.7","Cell RNA - NB-4 [nTPM]":"14.5","Cell RNA - NTERA-2 [nTPM]":"30.6","Cell RNA - OE19 [nTPM]":"21.6","Cell RNA - PC-3 [nTPM]":"15.4","Cell RNA - REH [nTPM]":"42.4","Cell RNA - RH-30 [nTPM]":"12.2","Cell RNA - RPMI-8226 [nTPM]":"38.8","Cell RNA - RPTEC TERT1 [nTPM]":"12.2","Cell RNA - RT4 [nTPM]":"10.5","Cell RNA - SCLC-21H [nTPM]":"30.4","Cell RNA - SH-SY5Y [nTPM]":"18.6","Cell RNA - SiHa [nTPM]":"22.6","Cell RNA - SK-BR-3 [nTPM]":"24.9","Cell RNA - SK-MEL-30 [nTPM]":"38.3","Cell RNA - SuSa [nTPM]":"10.0","Cell RNA - T-47d [nTPM]":"16.5","Cell RNA - THP-1 [nTPM]":"26.1","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"15.9","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"18.5","Cell RNA - U-251 MG [nTPM]":"17.5","Cell RNA - U-266\/70 [nTPM]":"17.3","Cell RNA - U-266\/84 [nTPM]":"18.1","Cell RNA - U-698 [nTPM]":"34.2","Cell RNA - U-87 MG [nTPM]":"7.5","Cell RNA - U-937 [nTPM]":"13.7","Cell RNA - WM-115 [nTPM]":"15.9","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"5.0","Blood RNA - gdT-cell [nTPM]":"8.3","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"7.6","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.4","Blood RNA - neutrophil [nTPM]":"2.7","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"0.6","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"14.8","Brain RNA - cerebral cortex [nTPM]":"12.5","Brain RNA - hippocampal formation [nTPM]":"10.0","Brain RNA - hypothalamus [nTPM]":"9.2","Brain RNA - medulla oblongata [nTPM]":"10.2","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.2","Brain RNA - thalamus [nTPM]":"10.1","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"7.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"4.9","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"4.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"7.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.5","Single Cell Type RNA - dendritic cells [nTPM]":"30.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.4","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"10.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.7","Single Cell Type RNA - Hepatocytes [nTPM]":"5.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"6.2","Single Cell Type RNA - Langerhans cells [nTPM]":"9.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"6.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"4.5","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.0","Single Cell Type RNA - Paneth cells [nTPM]":"12.2","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"7.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.6","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"12.4","Single Cell Type RNA - Theca cells [nTPM]":"5.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.7","Single Cell Type RNA - Urothelial cells [nTPM]":"10.5"},{"Gene":"AXIN2","Gene synonym":["DKFZp781B0869","MGC126582"],"Ensembl":"ENSG00000168646","Gene description":"Axin 2","Uniprot":["Q9Y2T1"],"Chromosome":"17","Position":"65528563-65561648","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"33.7","Extravillous trophoblasts":"102.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"33.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"3.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"27.2","CACO-2":"52.3","Hep G2":"78.8","OE19":"86.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB012283","CAB017783"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB012283":"AB_2290204","CAB017783":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.58e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.7","Tissue RNA - adrenal gland [nTPM]":"10.9","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"5.4","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"5.3","Tissue RNA - cerebellum [nTPM]":"7.9","Tissue RNA - cerebral cortex [nTPM]":"7.9","Tissue RNA - cervix [nTPM]":"17.2","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"12.3","Tissue RNA - duodenum [nTPM]":"7.1","Tissue RNA - endometrium 1 [nTPM]":"23.9","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"19.8","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"9.4","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"3.7","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"17.0","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"15.0","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"18.4","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"14.6","Tissue RNA - retina [nTPM]":"3.4","Tissue RNA - salivary gland [nTPM]":"5.2","Tissue RNA - seminal vesicle [nTPM]":"8.9","Tissue RNA - skeletal muscle [nTPM]":"14.6","Tissue RNA - skin 1 [nTPM]":"14.9","Tissue RNA - small intestine [nTPM]":"7.4","Tissue RNA - smooth muscle [nTPM]":"17.3","Tissue RNA - spinal cord [nTPM]":"7.3","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"13.6","Tissue RNA - testis [nTPM]":"6.7","Tissue RNA - thalamus [nTPM]":"11.0","Tissue RNA - thymus [nTPM]":"17.3","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"11.4","Tissue RNA - vagina [nTPM]":"8.0","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"13.9","Cell RNA - AF22 [nTPM]":"27.2","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"9.6","Cell RNA - ASC TERT1 [nTPM]":"4.1","Cell RNA - BEWO [nTPM]":"12.0","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.7","Cell RNA - CACO-2 [nTPM]":"52.3","Cell RNA - CAPAN-2 [nTPM]":"5.0","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"1.7","Cell RNA - fHDF\/TERT166 [nTPM]":"8.0","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"2.4","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.4","Cell RNA - Hep G2 [nTPM]":"78.8","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"2.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"1.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.4","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"1.4","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"5.3","Cell RNA - OE19 [nTPM]":"86.9","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.6","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"8.4","Cell RNA - SH-SY5Y [nTPM]":"5.5","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"4.8","Cell RNA - SuSa [nTPM]":"20.0","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"6.3","Cell RNA - U-138 MG [nTPM]":"5.3","Cell RNA - U-2 OS [nTPM]":"9.6","Cell RNA - U-2197 [nTPM]":"7.6","Cell RNA - U-251 MG [nTPM]":"1.7","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"3.0","Cell RNA - U-698 [nTPM]":"3.8","Cell RNA - U-87 MG [nTPM]":"2.5","Cell RNA - U-937 [nTPM]":"0.6","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"3.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"2.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"7.9","Brain RNA - cerebral cortex [nTPM]":"7.9","Brain RNA - hippocampal formation [nTPM]":"9.4","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"7.3","Brain RNA - thalamus [nTPM]":"11.0","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.0","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.4","Single Cell Type RNA - Early spermatids [nTPM]":"33.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.1","Single Cell Type RNA - Endothelial cells [nTPM]":"5.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"102.6","Single Cell Type RNA - Fibroblasts [nTPM]":"10.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.8","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"17.5","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"18.9","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.6","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"12.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.2","Single Cell Type RNA - T-cells [nTPM]":"4.6","Single Cell Type RNA - Theca cells [nTPM]":"3.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.8","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"B2M","Gene synonym":[],"Ensembl":"ENSG00000166710","Gene description":"Beta-2-microglobulin","Uniprot":["P61769"],"Chromosome":"15","Position":"44711487-44718851","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","Transporters"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":["Amyloidosis","Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"monocytes":"31919.3","NK-cells":"24726.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002572","HPA006361"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1790000000,"Blood concentration - Conc. blood MS [pg\/L]":"2100000000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":["Golgi apparatus","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB002572":"AB_563434","HPA006361":"AB_1078278"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.63e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.17e-2"},"Tissue RNA - adipose tissue [nTPM]":"3160.2","Tissue RNA - adrenal gland [nTPM]":"3214.7","Tissue RNA - amygdala [nTPM]":"697.6","Tissue RNA - appendix [nTPM]":"5686.5","Tissue RNA - basal ganglia [nTPM]":"705.1","Tissue RNA - bone marrow [nTPM]":"7839.2","Tissue RNA - breast [nTPM]":"2606.9","Tissue RNA - cerebellum [nTPM]":"711.8","Tissue RNA - cerebral cortex [nTPM]":"1145.0","Tissue RNA - cervix [nTPM]":"2539.9","Tissue RNA - choroid plexus [nTPM]":"789.6","Tissue RNA - colon [nTPM]":"5139.0","Tissue RNA - duodenum [nTPM]":"5180.7","Tissue RNA - endometrium 1 [nTPM]":"2192.2","Tissue RNA - epididymis [nTPM]":"1735.6","Tissue RNA - esophagus [nTPM]":"2283.9","Tissue RNA - fallopian tube [nTPM]":"1648.3","Tissue RNA - gallbladder [nTPM]":"4948.8","Tissue RNA - heart muscle [nTPM]":"2327.2","Tissue RNA - hippocampal formation [nTPM]":"651.0","Tissue RNA - hypothalamus [nTPM]":"769.9","Tissue RNA - kidney [nTPM]":"2462.6","Tissue RNA - liver [nTPM]":"6206.2","Tissue RNA - lung [nTPM]":"6159.2","Tissue RNA - lymph node [nTPM]":"9311.8","Tissue RNA - medulla oblongata [nTPM]":"889.5","Tissue RNA - midbrain [nTPM]":"763.2","Tissue RNA - ovary [nTPM]":"1945.7","Tissue RNA - pancreas [nTPM]":"1310.9","Tissue RNA - parathyroid gland [nTPM]":"1940.5","Tissue RNA - pituitary gland [nTPM]":"318.4","Tissue RNA - placenta [nTPM]":"3502.0","Tissue RNA - pons [nTPM]":"815.3","Tissue RNA - prostate [nTPM]":"2345.0","Tissue RNA - rectum [nTPM]":"5593.5","Tissue RNA - retina [nTPM]":"139.3","Tissue RNA - salivary gland [nTPM]":"5657.1","Tissue RNA - seminal vesicle [nTPM]":"1784.5","Tissue RNA - skeletal muscle [nTPM]":"931.7","Tissue RNA - skin 1 [nTPM]":"3015.6","Tissue RNA - small intestine [nTPM]":"5693.3","Tissue RNA - smooth muscle [nTPM]":"2545.3","Tissue RNA - spinal cord [nTPM]":"838.3","Tissue RNA - spleen [nTPM]":"7896.1","Tissue RNA - stomach 1 [nTPM]":"4878.2","Tissue RNA - testis [nTPM]":"615.6","Tissue RNA - thalamus [nTPM]":"771.9","Tissue RNA - thymus [nTPM]":"4217.4","Tissue RNA - thyroid gland [nTPM]":"2340.8","Tissue RNA - tongue [nTPM]":"2026.5","Tissue RNA - tonsil [nTPM]":"5333.4","Tissue RNA - urinary bladder [nTPM]":"5753.1","Tissue RNA - vagina [nTPM]":"549.4","Tissue RNA - white matter [nTPM]":"909.5","Cell RNA - A-431 [nTPM]":"1735.4","Cell RNA - A549 [nTPM]":"378.9","Cell RNA - AF22 [nTPM]":"226.0","Cell RNA - AN3-CA [nTPM]":"633.6","Cell RNA - ASC diff [nTPM]":"4348.7","Cell RNA - ASC TERT1 [nTPM]":"4719.4","Cell RNA - BEWO [nTPM]":"1662.5","Cell RNA - BJ [nTPM]":"2045.5","Cell RNA - BJ hTERT+ [nTPM]":"4961.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3609.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6561.4","Cell RNA - CACO-2 [nTPM]":"425.3","Cell RNA - CAPAN-2 [nTPM]":"5417.9","Cell RNA - Daudi [nTPM]":"554.8","Cell RNA - EFO-21 [nTPM]":"2567.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1948.8","Cell RNA - GAMG [nTPM]":"2410.2","Cell RNA - HaCaT [nTPM]":"2537.0","Cell RNA - HAP1 [nTPM]":"497.2","Cell RNA - HBEC3-KT [nTPM]":"878.7","Cell RNA - HBF TERT88 [nTPM]":"1226.2","Cell RNA - HDLM-2 [nTPM]":"4762.2","Cell RNA - HEK 293 [nTPM]":"435.9","Cell RNA - HEL [nTPM]":"2956.9","Cell RNA - HeLa [nTPM]":"2263.6","Cell RNA - Hep G2 [nTPM]":"600.3","Cell RNA - HHSteC [nTPM]":"3609.3","Cell RNA - HL-60 [nTPM]":"2074.5","Cell RNA - HMC-1 [nTPM]":"3328.6","Cell RNA - HSkMC [nTPM]":"2735.9","Cell RNA - hTCEpi [nTPM]":"609.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1075.7","Cell RNA - hTERT-HME1 [nTPM]":"1044.4","Cell RNA - hTERT-RPE1 [nTPM]":"2442.6","Cell RNA - HUVEC TERT2 [nTPM]":"1884.1","Cell RNA - JURKAT [nTPM]":"965.4","Cell RNA - K-562 [nTPM]":"611.9","Cell RNA - Karpas-707 [nTPM]":"3649.1","Cell RNA - LHCN-M2 [nTPM]":"2195.5","Cell RNA - MCF7 [nTPM]":"476.9","Cell RNA - MOLT-4 [nTPM]":"1518.4","Cell RNA - NB-4 [nTPM]":"3213.8","Cell RNA - NTERA-2 [nTPM]":"206.5","Cell RNA - OE19 [nTPM]":"629.8","Cell RNA - PC-3 [nTPM]":"1014.3","Cell RNA - REH [nTPM]":"2240.2","Cell RNA - RH-30 [nTPM]":"1926.6","Cell RNA - RPMI-8226 [nTPM]":"4789.2","Cell RNA - RPTEC TERT1 [nTPM]":"2425.5","Cell RNA - RT4 [nTPM]":"3486.4","Cell RNA - SCLC-21H [nTPM]":"254.1","Cell RNA - SH-SY5Y [nTPM]":"179.1","Cell RNA - SiHa [nTPM]":"1288.4","Cell RNA - SK-BR-3 [nTPM]":"1571.2","Cell RNA - SK-MEL-30 [nTPM]":"1338.5","Cell RNA - SuSa [nTPM]":"394.3","Cell RNA - T-47d [nTPM]":"655.3","Cell RNA - THP-1 [nTPM]":"6180.6","Cell RNA - TIME [nTPM]":"2548.7","Cell RNA - U-138 MG [nTPM]":"4531.4","Cell RNA - U-2 OS [nTPM]":"676.5","Cell RNA - U-2197 [nTPM]":"5389.2","Cell RNA - U-251 MG [nTPM]":"2193.3","Cell RNA - U-266\/70 [nTPM]":"4771.7","Cell RNA - U-266\/84 [nTPM]":"7118.6","Cell RNA - U-698 [nTPM]":"1683.1","Cell RNA - U-87 MG [nTPM]":"5384.6","Cell RNA - U-937 [nTPM]":"3783.6","Cell RNA - WM-115 [nTPM]":"2567.3","Blood RNA - basophil [nTPM]":"48105.4","Blood RNA - classical monocyte [nTPM]":"18117.1","Blood RNA - eosinophil [nTPM]":"33178.9","Blood RNA - gdT-cell [nTPM]":"20639.1","Blood RNA - intermediate monocyte [nTPM]":"17775.0","Blood RNA - MAIT T-cell [nTPM]":"20836.8","Blood RNA - memory B-cell [nTPM]":"15768.0","Blood RNA - memory CD4 T-cell [nTPM]":"23783.0","Blood RNA - memory CD8 T-cell [nTPM]":"22245.1","Blood RNA - myeloid DC [nTPM]":"9978.8","Blood RNA - naive B-cell [nTPM]":"11988.4","Blood RNA - naive CD4 T-cell [nTPM]":"17122.9","Blood RNA - naive CD8 T-cell [nTPM]":"22791.8","Blood RNA - neutrophil [nTPM]":"50453.6","Blood RNA - NK-cell [nTPM]":"18779.6","Blood RNA - non-classical monocyte [nTPM]":"19034.9","Blood RNA - plasmacytoid DC [nTPM]":"12052.6","Blood RNA - T-reg [nTPM]":"29659.1","Blood RNA - total PBMC [nTPM]":"56957.2","Brain RNA - amygdala [nTPM]":"697.6","Brain RNA - basal ganglia [nTPM]":"705.1","Brain RNA - cerebellum [nTPM]":"711.8","Brain RNA - cerebral cortex [nTPM]":"1145.0","Brain RNA - hippocampal formation [nTPM]":"651.0","Brain RNA - hypothalamus [nTPM]":"769.9","Brain RNA - medulla oblongata [nTPM]":"889.5","Brain RNA - midbrain [nTPM]":"763.2","Brain RNA - pons [nTPM]":"815.3","Brain RNA - spinal cord [nTPM]":"838.3","Brain RNA - thalamus [nTPM]":"771.9","Brain RNA - white matter [nTPM]":"909.5","Single Cell Type RNA - Adipocytes [nTPM]":"12048.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3387.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3505.1","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"8472.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7843.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3197.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8420.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1628.8","Single Cell Type RNA - Bipolar cells [nTPM]":"33.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2399.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2015.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1068.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"3593.1","Single Cell Type RNA - Club cells [nTPM]":"5347.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"2100.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1354.6","Single Cell Type RNA - dendritic cells [nTPM]":"14028.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"8753.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1038.9","Single Cell Type RNA - Ductal cells [nTPM]":"13898.6","Single Cell Type RNA - Early spermatids [nTPM]":"43.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2073.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2414.0","Single Cell Type RNA - Endothelial cells [nTPM]":"8385.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2266.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2087.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9034.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4397.5","Single Cell Type RNA - Fibroblasts [nTPM]":"3691.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1981.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2282.2","Single Cell Type RNA - granulocytes [nTPM]":"3029.5","Single Cell Type RNA - Granulosa cells [nTPM]":"1270.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6835.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3832.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11985.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5982.6","Single Cell Type RNA - Ionocytes [nTPM]":"8701.4","Single Cell Type RNA - Kupffer cells [nTPM]":"12536.8","Single Cell Type RNA - Langerhans cells [nTPM]":"14507.0","Single Cell Type RNA - Late spermatids [nTPM]":"158.8","Single Cell Type RNA - Leydig cells [nTPM]":"3018.0","Single Cell Type RNA - Macrophages [nTPM]":"10687.9","Single Cell Type RNA - Melanocytes [nTPM]":"6744.8","Single Cell Type RNA - Microglial cells [nTPM]":"368.2","Single Cell Type RNA - monocytes [nTPM]":"31919.3","Single Cell Type RNA - Muller glia cells [nTPM]":"322.0","Single Cell Type RNA - NK-cells [nTPM]":"24726.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"95.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"129.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10115.7","Single Cell Type RNA - Paneth cells [nTPM]":"7085.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1688.8","Single Cell Type RNA - Plasma cells [nTPM]":"11026.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5300.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18327.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3122.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8367.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"52.5","Single Cell Type RNA - Sertoli cells [nTPM]":"4016.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2055.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4107.1","Single Cell Type RNA - Spermatocytes [nTPM]":"64.2","Single Cell Type RNA - Spermatogonia [nTPM]":"72.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1541.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8619.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"804.8","Single Cell Type RNA - T-cells [nTPM]":"14266.2","Single Cell Type RNA - Theca cells [nTPM]":"3229.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3063.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8248.6"},{"Gene":"BAX","Gene synonym":["BCL2L4"],"Ensembl":"ENSG00000087088","Gene description":"BCL2 associated X, apoptosis regulator","Uniprot":["Q07812"],"Chromosome":"19","Position":"48954815-48961798","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transporters"],"Biological process":["Apoptosis","Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004206","HPA027878"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1100000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004206":"AB_626729","HPA027878":"AB_10601687"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.70e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.63e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Tissue RNA - adipose tissue [nTPM]":"30.2","Tissue RNA - adrenal gland [nTPM]":"30.4","Tissue RNA - amygdala [nTPM]":"24.4","Tissue RNA - appendix [nTPM]":"59.2","Tissue RNA - basal ganglia [nTPM]":"26.8","Tissue RNA - bone marrow [nTPM]":"65.7","Tissue RNA - breast [nTPM]":"27.2","Tissue RNA - cerebellum [nTPM]":"25.5","Tissue RNA - cerebral cortex [nTPM]":"29.3","Tissue RNA - cervix [nTPM]":"27.6","Tissue RNA - choroid plexus [nTPM]":"23.9","Tissue RNA - colon [nTPM]":"78.1","Tissue RNA - duodenum [nTPM]":"68.2","Tissue RNA - endometrium 1 [nTPM]":"29.9","Tissue RNA - epididymis [nTPM]":"23.2","Tissue RNA - esophagus [nTPM]":"35.8","Tissue RNA - fallopian tube [nTPM]":"33.2","Tissue RNA - gallbladder [nTPM]":"37.6","Tissue RNA - heart muscle [nTPM]":"22.6","Tissue RNA - hippocampal formation [nTPM]":"24.5","Tissue RNA - hypothalamus [nTPM]":"25.5","Tissue RNA - kidney [nTPM]":"31.0","Tissue RNA - liver [nTPM]":"33.4","Tissue RNA - lung [nTPM]":"46.0","Tissue RNA - lymph node [nTPM]":"59.5","Tissue RNA - medulla oblongata [nTPM]":"27.1","Tissue RNA - midbrain [nTPM]":"25.4","Tissue RNA - ovary [nTPM]":"19.6","Tissue RNA - pancreas [nTPM]":"32.7","Tissue RNA - parathyroid gland [nTPM]":"26.1","Tissue RNA - pituitary gland [nTPM]":"15.9","Tissue RNA - placenta [nTPM]":"43.3","Tissue RNA - pons [nTPM]":"27.0","Tissue RNA - prostate [nTPM]":"25.7","Tissue RNA - rectum [nTPM]":"58.8","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"26.5","Tissue RNA - seminal vesicle [nTPM]":"27.0","Tissue RNA - skeletal muscle [nTPM]":"18.1","Tissue RNA - skin 1 [nTPM]":"29.8","Tissue RNA - small intestine [nTPM]":"64.6","Tissue RNA - smooth muscle [nTPM]":"36.3","Tissue RNA - spinal cord [nTPM]":"26.1","Tissue RNA - spleen [nTPM]":"60.0","Tissue RNA - stomach 1 [nTPM]":"43.8","Tissue RNA - testis [nTPM]":"12.4","Tissue RNA - thalamus [nTPM]":"26.3","Tissue RNA - thymus [nTPM]":"83.2","Tissue RNA - thyroid gland [nTPM]":"23.4","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"44.7","Tissue RNA - urinary bladder [nTPM]":"46.7","Tissue RNA - vagina [nTPM]":"26.1","Tissue RNA - white matter [nTPM]":"27.1","Cell RNA - A-431 [nTPM]":"177.4","Cell RNA - A549 [nTPM]":"286.0","Cell RNA - AF22 [nTPM]":"170.1","Cell RNA - AN3-CA [nTPM]":"150.4","Cell RNA - ASC diff [nTPM]":"165.4","Cell RNA - ASC TERT1 [nTPM]":"161.7","Cell RNA - BEWO [nTPM]":"280.2","Cell RNA - BJ [nTPM]":"117.8","Cell RNA - BJ hTERT+ [nTPM]":"233.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"151.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"210.6","Cell RNA - CACO-2 [nTPM]":"76.4","Cell RNA - CAPAN-2 [nTPM]":"168.6","Cell RNA - Daudi [nTPM]":"214.6","Cell RNA - EFO-21 [nTPM]":"53.9","Cell RNA - fHDF\/TERT166 [nTPM]":"181.2","Cell RNA - GAMG [nTPM]":"141.3","Cell RNA - HaCaT [nTPM]":"93.8","Cell RNA - HAP1 [nTPM]":"78.0","Cell RNA - HBEC3-KT [nTPM]":"229.0","Cell RNA - HBF TERT88 [nTPM]":"125.7","Cell RNA - HDLM-2 [nTPM]":"166.6","Cell RNA - HEK 293 [nTPM]":"181.0","Cell RNA - HEL [nTPM]":"91.9","Cell RNA - HeLa [nTPM]":"56.6","Cell RNA - Hep G2 [nTPM]":"288.0","Cell RNA - HHSteC [nTPM]":"265.7","Cell RNA - HL-60 [nTPM]":"96.3","Cell RNA - HMC-1 [nTPM]":"280.9","Cell RNA - HSkMC [nTPM]":"222.3","Cell RNA - hTCEpi [nTPM]":"161.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"126.1","Cell RNA - hTERT-HME1 [nTPM]":"75.5","Cell RNA - hTERT-RPE1 [nTPM]":"183.3","Cell RNA - HUVEC TERT2 [nTPM]":"354.6","Cell RNA - JURKAT [nTPM]":"83.4","Cell RNA - K-562 [nTPM]":"91.4","Cell RNA - Karpas-707 [nTPM]":"86.0","Cell RNA - LHCN-M2 [nTPM]":"264.8","Cell RNA - MCF7 [nTPM]":"123.1","Cell RNA - MOLT-4 [nTPM]":"157.6","Cell RNA - NB-4 [nTPM]":"150.3","Cell RNA - NTERA-2 [nTPM]":"132.8","Cell RNA - OE19 [nTPM]":"171.3","Cell RNA - PC-3 [nTPM]":"82.5","Cell RNA - REH [nTPM]":"109.2","Cell RNA - RH-30 [nTPM]":"113.1","Cell RNA - RPMI-8226 [nTPM]":"82.4","Cell RNA - RPTEC TERT1 [nTPM]":"161.0","Cell RNA - RT4 [nTPM]":"168.4","Cell RNA - SCLC-21H [nTPM]":"97.4","Cell RNA - SH-SY5Y [nTPM]":"114.7","Cell RNA - SiHa [nTPM]":"99.2","Cell RNA - SK-BR-3 [nTPM]":"69.8","Cell RNA - SK-MEL-30 [nTPM]":"57.4","Cell RNA - SuSa [nTPM]":"240.6","Cell RNA - T-47d [nTPM]":"56.2","Cell RNA - THP-1 [nTPM]":"171.2","Cell RNA - TIME [nTPM]":"210.2","Cell RNA - U-138 MG [nTPM]":"194.0","Cell RNA - U-2 OS [nTPM]":"212.1","Cell RNA - U-2197 [nTPM]":"120.1","Cell RNA - U-251 MG [nTPM]":"165.1","Cell RNA - U-266\/70 [nTPM]":"97.9","Cell RNA - U-266\/84 [nTPM]":"136.6","Cell RNA - U-698 [nTPM]":"145.0","Cell RNA - U-87 MG [nTPM]":"118.1","Cell RNA - U-937 [nTPM]":"129.2","Cell RNA - WM-115 [nTPM]":"275.1","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"12.1","Blood RNA - eosinophil [nTPM]":"13.4","Blood RNA - gdT-cell [nTPM]":"6.5","Blood RNA - intermediate monocyte [nTPM]":"18.4","Blood RNA - MAIT T-cell [nTPM]":"4.6","Blood RNA - memory B-cell [nTPM]":"7.3","Blood RNA - memory CD4 T-cell [nTPM]":"3.7","Blood RNA - memory CD8 T-cell [nTPM]":"7.1","Blood RNA - myeloid DC [nTPM]":"12.2","Blood RNA - naive B-cell [nTPM]":"5.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"13.1","Blood RNA - NK-cell [nTPM]":"12.2","Blood RNA - non-classical monocyte [nTPM]":"20.9","Blood RNA - plasmacytoid DC [nTPM]":"12.5","Blood RNA - T-reg [nTPM]":"7.5","Blood RNA - total PBMC [nTPM]":"8.4","Brain RNA - amygdala [nTPM]":"24.4","Brain RNA - basal ganglia [nTPM]":"26.8","Brain RNA - cerebellum [nTPM]":"25.5","Brain RNA - cerebral cortex [nTPM]":"29.3","Brain RNA - hippocampal formation [nTPM]":"24.5","Brain RNA - hypothalamus [nTPM]":"25.5","Brain RNA - medulla oblongata [nTPM]":"27.1","Brain RNA - midbrain [nTPM]":"25.4","Brain RNA - pons [nTPM]":"27.0","Brain RNA - spinal cord [nTPM]":"26.1","Brain RNA - thalamus [nTPM]":"26.3","Brain RNA - white matter [nTPM]":"27.1","Single Cell Type RNA - Adipocytes [nTPM]":"83.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.8","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"164.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"63.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"160.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"101.3","Single Cell Type RNA - Bipolar cells [nTPM]":"19.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"64.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"67.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"78.6","Single Cell Type RNA - Club cells [nTPM]":"98.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"126.0","Single Cell Type RNA - dendritic cells [nTPM]":"130.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"152.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"122.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"65.7","Single Cell Type RNA - Endothelial cells [nTPM]":"83.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"114.0","Single Cell Type RNA - Erythroid cells [nTPM]":"79.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"96.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"157.9","Single Cell Type RNA - Fibroblasts [nTPM]":"57.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"114.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"46.0","Single Cell Type RNA - granulocytes [nTPM]":"43.9","Single Cell Type RNA - Granulosa cells [nTPM]":"151.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"59.3","Single Cell Type RNA - Hepatocytes [nTPM]":"28.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"263.6","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"102.7","Single Cell Type RNA - Ionocytes [nTPM]":"209.5","Single Cell Type RNA - Kupffer cells [nTPM]":"121.8","Single Cell Type RNA - Langerhans cells [nTPM]":"143.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"48.1","Single Cell Type RNA - Macrophages [nTPM]":"148.3","Single Cell Type RNA - Melanocytes [nTPM]":"83.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"295.3","Single Cell Type RNA - Muller glia cells [nTPM]":"43.9","Single Cell Type RNA - NK-cells [nTPM]":"140.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"139.4","Single Cell Type RNA - Paneth cells [nTPM]":"177.0","Single Cell Type RNA - Peritubular cells [nTPM]":"38.4","Single Cell Type RNA - Plasma cells [nTPM]":"96.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"126.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"229.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"227.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"66.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.9","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"259.4","Single Cell Type RNA - Spermatocytes [nTPM]":"20.3","Single Cell Type RNA - Spermatogonia [nTPM]":"38.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"92.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"101.9","Single Cell Type RNA - T-cells [nTPM]":"149.4","Single Cell Type RNA - Theca cells [nTPM]":"175.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"149.7","Single Cell Type RNA - Urothelial cells [nTPM]":"86.7"},{"Gene":"BCL2","Gene synonym":["Bcl-2","PPP1R50"],"Ensembl":"ENSG00000171791","Gene description":"BCL2 apoptosis regulator","Uniprot":["P10415"],"Chromosome":"18","Position":"63123346-63320128","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Apoptosis"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"271.6","Inhibitory neurons":"102.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"18","RNA blood lineage specific nTPM":{"B-cells":"5.4","T-cells":"8.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"44.2","HL-60":"43.7","Karpas-707":"72.9","U-266\/70":"217.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000003","HPA055295"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: T-cells - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB000003":"AB_2064429","HPA055295":"AB_2682776"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.13e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.05e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.78e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.29e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.47e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"10.2","Tissue RNA - basal ganglia [nTPM]":"7.8","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"9.6","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"3.4","Tissue RNA - cervix [nTPM]":"10.7","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"4.4","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"11.8","Tissue RNA - gallbladder [nTPM]":"6.5","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"6.6","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"2.1","Tissue RNA - lung [nTPM]":"3.7","Tissue RNA - lymph node [nTPM]":"14.7","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"7.9","Tissue RNA - ovary [nTPM]":"14.5","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"4.7","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"7.5","Tissue RNA - prostate [nTPM]":"6.4","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"16.5","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"8.1","Tissue RNA - smooth muscle [nTPM]":"6.6","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"17.9","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"8.2","Tissue RNA - thymus [nTPM]":"18.3","Tissue RNA - thyroid gland [nTPM]":"24.0","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"14.6","Tissue RNA - urinary bladder [nTPM]":"5.4","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"5.7","Cell RNA - A-431 [nTPM]":"1.7","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"6.8","Cell RNA - AN3-CA [nTPM]":"5.9","Cell RNA - ASC diff [nTPM]":"6.7","Cell RNA - ASC TERT1 [nTPM]":"1.3","Cell RNA - BEWO [nTPM]":"2.4","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.0","Cell RNA - CACO-2 [nTPM]":"3.5","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"1.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"4.7","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"6.7","Cell RNA - HBEC3-KT [nTPM]":"0.9","Cell RNA - HBF TERT88 [nTPM]":"1.5","Cell RNA - HDLM-2 [nTPM]":"44.2","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.5","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"0.7","Cell RNA - HHSteC [nTPM]":"2.0","Cell RNA - HL-60 [nTPM]":"43.7","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"1.7","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"5.8","Cell RNA - hTERT-RPE1 [nTPM]":"1.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"4.3","Cell RNA - K-562 [nTPM]":"0.8","Cell RNA - Karpas-707 [nTPM]":"72.9","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"9.8","Cell RNA - NB-4 [nTPM]":"10.7","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"39.5","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"26.5","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"8.5","Cell RNA - SCLC-21H [nTPM]":"7.2","Cell RNA - SH-SY5Y [nTPM]":"6.4","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"8.5","Cell RNA - SuSa [nTPM]":"1.4","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"29.9","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"9.9","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.9","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"217.4","Cell RNA - U-266\/84 [nTPM]":"40.1","Cell RNA - U-698 [nTPM]":"2.9","Cell RNA - U-87 MG [nTPM]":"1.9","Cell RNA - U-937 [nTPM]":"24.9","Cell RNA - WM-115 [nTPM]":"6.0","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"7.6","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.3","Blood RNA - memory CD8 T-cell [nTPM]":"3.4","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"3.3","Blood RNA - naive CD8 T-cell [nTPM]":"3.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"8.5","Blood RNA - total PBMC [nTPM]":"1.3","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"7.8","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"3.4","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"6.6","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"7.9","Brain RNA - pons [nTPM]":"7.5","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"8.2","Brain RNA - white matter [nTPM]":"5.7","Single Cell Type RNA - Adipocytes [nTPM]":"7.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"271.6","Single Cell Type RNA - B-cells [nTPM]":"84.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - dendritic cells [nTPM]":"39.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"3.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"3.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"60.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"15.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.9","Single Cell Type RNA - granulocytes [nTPM]":"15.8","Single Cell Type RNA - Granulosa cells [nTPM]":"38.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"102.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.5","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"15.0","Single Cell Type RNA - Langerhans cells [nTPM]":"29.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"29.0","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"88.1","Single Cell Type RNA - monocytes [nTPM]":"19.7","Single Cell Type RNA - Muller glia cells [nTPM]":"18.8","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"76.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"56.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"5.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"50.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"48.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.1","Single Cell Type RNA - T-cells [nTPM]":"76.1","Single Cell Type RNA - Theca cells [nTPM]":"24.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.8","Single Cell Type RNA - Urothelial cells [nTPM]":"76.2"},{"Gene":"BCL6","Gene synonym":["BCL5","BCL6A","LAZ3","ZBTB27","ZNF51"],"Ensembl":"ENSG00000113916","Gene description":"BCL6 transcription repressor","Uniprot":["P41182"],"Chromosome":"3","Position":"187721377-187745725","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Immunity","Inflammatory response","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"485.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"205.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"neutrophil":"269.1","non-classical monocyte":"76.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"269.1","monocytes":"76.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"166.4","HSkMC":"113.9","U-698":"231.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000307","HPA004899","HPA050645"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000307":"AB_2063451","HPA004899":"AB_1078273","HPA050645":"AB_2681199"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.34e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.27e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"143.0","Tissue RNA - adrenal gland [nTPM]":"49.4","Tissue RNA - amygdala [nTPM]":"54.3","Tissue RNA - appendix [nTPM]":"53.9","Tissue RNA - basal ganglia [nTPM]":"53.4","Tissue RNA - bone marrow [nTPM]":"123.7","Tissue RNA - breast [nTPM]":"126.9","Tissue RNA - cerebellum [nTPM]":"85.9","Tissue RNA - cerebral cortex [nTPM]":"57.9","Tissue RNA - cervix [nTPM]":"100.0","Tissue RNA - choroid plexus [nTPM]":"35.0","Tissue RNA - colon [nTPM]":"87.1","Tissue RNA - duodenum [nTPM]":"7.5","Tissue RNA - endometrium 1 [nTPM]":"68.1","Tissue RNA - epididymis [nTPM]":"16.4","Tissue RNA - esophagus [nTPM]":"44.6","Tissue RNA - fallopian tube [nTPM]":"140.7","Tissue RNA - gallbladder [nTPM]":"45.6","Tissue RNA - heart muscle [nTPM]":"72.1","Tissue RNA - hippocampal formation [nTPM]":"50.9","Tissue RNA - hypothalamus [nTPM]":"68.7","Tissue RNA - kidney [nTPM]":"37.0","Tissue RNA - liver [nTPM]":"65.3","Tissue RNA - lung [nTPM]":"110.5","Tissue RNA - lymph node [nTPM]":"56.0","Tissue RNA - medulla oblongata [nTPM]":"104.1","Tissue RNA - midbrain [nTPM]":"69.4","Tissue RNA - ovary [nTPM]":"65.6","Tissue RNA - pancreas [nTPM]":"49.2","Tissue RNA - parathyroid gland [nTPM]":"11.3","Tissue RNA - pituitary gland [nTPM]":"44.8","Tissue RNA - placenta [nTPM]":"15.3","Tissue RNA - pons [nTPM]":"74.2","Tissue RNA - prostate [nTPM]":"57.5","Tissue RNA - rectum [nTPM]":"10.3","Tissue RNA - retina [nTPM]":"34.2","Tissue RNA - salivary gland [nTPM]":"70.3","Tissue RNA - seminal vesicle [nTPM]":"22.2","Tissue RNA - skeletal muscle [nTPM]":"485.9","Tissue RNA - skin 1 [nTPM]":"160.7","Tissue RNA - small intestine [nTPM]":"34.4","Tissue RNA - smooth muscle [nTPM]":"43.0","Tissue RNA - spinal cord [nTPM]":"55.9","Tissue RNA - spleen [nTPM]":"106.3","Tissue RNA - stomach 1 [nTPM]":"58.4","Tissue RNA - testis [nTPM]":"18.6","Tissue RNA - thalamus [nTPM]":"69.0","Tissue RNA - thymus [nTPM]":"43.2","Tissue RNA - thyroid gland [nTPM]":"50.4","Tissue RNA - tongue [nTPM]":"96.6","Tissue RNA - tonsil [nTPM]":"47.7","Tissue RNA - urinary bladder [nTPM]":"90.6","Tissue RNA - vagina [nTPM]":"81.5","Tissue RNA - white matter [nTPM]":"64.1","Cell RNA - A-431 [nTPM]":"5.1","Cell RNA - A549 [nTPM]":"13.8","Cell RNA - AF22 [nTPM]":"14.4","Cell RNA - AN3-CA [nTPM]":"3.2","Cell RNA - ASC diff [nTPM]":"98.1","Cell RNA - ASC TERT1 [nTPM]":"78.0","Cell RNA - BEWO [nTPM]":"14.9","Cell RNA - BJ [nTPM]":"16.5","Cell RNA - BJ hTERT+ [nTPM]":"39.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"19.4","Cell RNA - CACO-2 [nTPM]":"9.4","Cell RNA - CAPAN-2 [nTPM]":"7.6","Cell RNA - Daudi [nTPM]":"166.4","Cell RNA - EFO-21 [nTPM]":"11.5","Cell RNA - fHDF\/TERT166 [nTPM]":"21.0","Cell RNA - GAMG [nTPM]":"11.7","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"4.4","Cell RNA - HBEC3-KT [nTPM]":"10.6","Cell RNA - HBF TERT88 [nTPM]":"15.3","Cell RNA - HDLM-2 [nTPM]":"33.8","Cell RNA - HEK 293 [nTPM]":"5.1","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"6.7","Cell RNA - Hep G2 [nTPM]":"22.5","Cell RNA - HHSteC [nTPM]":"51.5","Cell RNA - HL-60 [nTPM]":"2.1","Cell RNA - HMC-1 [nTPM]":"0.9","Cell RNA - HSkMC [nTPM]":"113.9","Cell RNA - hTCEpi [nTPM]":"68.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"22.7","Cell RNA - hTERT-HME1 [nTPM]":"32.9","Cell RNA - hTERT-RPE1 [nTPM]":"60.1","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"1.6","Cell RNA - Karpas-707 [nTPM]":"27.6","Cell RNA - LHCN-M2 [nTPM]":"18.2","Cell RNA - MCF7 [nTPM]":"5.7","Cell RNA - MOLT-4 [nTPM]":"5.5","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"1.4","Cell RNA - OE19 [nTPM]":"3.0","Cell RNA - PC-3 [nTPM]":"10.3","Cell RNA - REH [nTPM]":"45.4","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"0.8","Cell RNA - RPTEC TERT1 [nTPM]":"13.6","Cell RNA - RT4 [nTPM]":"23.2","Cell RNA - SCLC-21H [nTPM]":"3.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"18.8","Cell RNA - SK-BR-3 [nTPM]":"8.1","Cell RNA - SK-MEL-30 [nTPM]":"11.0","Cell RNA - SuSa [nTPM]":"30.2","Cell RNA - T-47d [nTPM]":"35.3","Cell RNA - THP-1 [nTPM]":"5.9","Cell RNA - TIME [nTPM]":"21.2","Cell RNA - U-138 MG [nTPM]":"43.7","Cell RNA - U-2 OS [nTPM]":"7.1","Cell RNA - U-2197 [nTPM]":"16.6","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"21.2","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"231.6","Cell RNA - U-87 MG [nTPM]":"24.2","Cell RNA - U-937 [nTPM]":"6.0","Cell RNA - WM-115 [nTPM]":"31.7","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"33.0","Blood RNA - eosinophil [nTPM]":"18.9","Blood RNA - gdT-cell [nTPM]":"5.5","Blood RNA - intermediate monocyte [nTPM]":"37.3","Blood RNA - MAIT T-cell [nTPM]":"5.4","Blood RNA - memory B-cell [nTPM]":"6.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"24.6","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"2.3","Blood RNA - neutrophil [nTPM]":"269.1","Blood RNA - NK-cell [nTPM]":"3.9","Blood RNA - non-classical monocyte [nTPM]":"76.4","Blood RNA - plasmacytoid DC [nTPM]":"4.0","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"30.7","Brain RNA - amygdala [nTPM]":"54.3","Brain RNA - basal ganglia [nTPM]":"53.4","Brain RNA - cerebellum [nTPM]":"85.9","Brain RNA - cerebral cortex [nTPM]":"57.9","Brain RNA - hippocampal formation [nTPM]":"50.9","Brain RNA - hypothalamus [nTPM]":"68.7","Brain RNA - medulla oblongata [nTPM]":"104.1","Brain RNA - midbrain [nTPM]":"69.4","Brain RNA - pons [nTPM]":"74.2","Brain RNA - spinal cord [nTPM]":"55.9","Brain RNA - thalamus [nTPM]":"69.0","Brain RNA - white matter [nTPM]":"64.1","Single Cell Type RNA - Adipocytes [nTPM]":"35.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"67.4","Single Cell Type RNA - Astrocytes [nTPM]":"66.0","Single Cell Type RNA - B-cells [nTPM]":"22.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"47.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"205.5","Single Cell Type RNA - Bipolar cells [nTPM]":"10.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"54.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"71.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"28.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"36.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"12.2","Single Cell Type RNA - Early spermatids [nTPM]":"13.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.7","Single Cell Type RNA - Endothelial cells [nTPM]":"25.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"57.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"51.4","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"9.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.0","Single Cell Type RNA - Hepatocytes [nTPM]":"51.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"67.5","Single Cell Type RNA - Langerhans cells [nTPM]":"74.4","Single Cell Type RNA - Late spermatids [nTPM]":"8.6","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"48.1","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"16.8","Single Cell Type RNA - Muller glia cells [nTPM]":"39.1","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"50.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"14.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"27.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"77.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"84.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.1","Single Cell Type RNA - T-cells [nTPM]":"30.0","Single Cell Type RNA - Theca cells [nTPM]":"10.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"2.8","Single Cell Type RNA - Urothelial cells [nTPM]":"29.7"},{"Gene":"BMI1","Gene synonym":["PCGF4","RNF51"],"Ensembl":"ENSG00000168283","Gene description":"BMI1 proto-oncogene, polycomb ring finger","Uniprot":["P35226"],"Chromosome":"10","Position":"22321099-22331484","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Repressor"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"134.0","Late spermatids":"165.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"508.3","U-937":"583.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011120","HPA030471","HPA030472"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Nucleoli","Cytosol"],"Antibody RRID":{"CAB011120":null,"HPA030471":"AB_2673491","HPA030472":"AB_10601090"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.60e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.44e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.73e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.0","Tissue RNA - adrenal gland [nTPM]":"31.1","Tissue RNA - amygdala [nTPM]":"26.6","Tissue RNA - appendix [nTPM]":"25.1","Tissue RNA - basal ganglia [nTPM]":"35.1","Tissue RNA - bone marrow [nTPM]":"21.9","Tissue RNA - breast [nTPM]":"36.0","Tissue RNA - cerebellum [nTPM]":"29.9","Tissue RNA - cerebral cortex [nTPM]":"42.4","Tissue RNA - cervix [nTPM]":"27.6","Tissue RNA - choroid plexus [nTPM]":"28.2","Tissue RNA - colon [nTPM]":"26.2","Tissue RNA - duodenum [nTPM]":"19.7","Tissue RNA - endometrium 1 [nTPM]":"30.7","Tissue RNA - epididymis [nTPM]":"29.7","Tissue RNA - esophagus [nTPM]":"21.9","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"23.9","Tissue RNA - heart muscle [nTPM]":"20.5","Tissue RNA - hippocampal formation [nTPM]":"25.0","Tissue RNA - hypothalamus [nTPM]":"27.8","Tissue RNA - kidney [nTPM]":"26.0","Tissue RNA - liver [nTPM]":"35.6","Tissue RNA - lung [nTPM]":"23.4","Tissue RNA - lymph node [nTPM]":"27.7","Tissue RNA - medulla oblongata [nTPM]":"29.5","Tissue RNA - midbrain [nTPM]":"30.1","Tissue RNA - ovary [nTPM]":"21.7","Tissue RNA - pancreas [nTPM]":"25.7","Tissue RNA - parathyroid gland [nTPM]":"56.9","Tissue RNA - pituitary gland [nTPM]":"25.0","Tissue RNA - placenta [nTPM]":"28.7","Tissue RNA - pons [nTPM]":"31.6","Tissue RNA - prostate [nTPM]":"33.7","Tissue RNA - rectum [nTPM]":"21.5","Tissue RNA - retina [nTPM]":"40.4","Tissue RNA - salivary gland [nTPM]":"19.9","Tissue RNA - seminal vesicle [nTPM]":"26.1","Tissue RNA - skeletal muscle [nTPM]":"44.4","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"20.8","Tissue RNA - smooth muscle [nTPM]":"36.2","Tissue RNA - spinal cord [nTPM]":"29.9","Tissue RNA - spleen [nTPM]":"36.2","Tissue RNA - stomach 1 [nTPM]":"22.5","Tissue RNA - testis [nTPM]":"35.3","Tissue RNA - thalamus [nTPM]":"28.1","Tissue RNA - thymus [nTPM]":"24.9","Tissue RNA - thyroid gland [nTPM]":"23.9","Tissue RNA - tongue [nTPM]":"35.5","Tissue RNA - tonsil [nTPM]":"27.0","Tissue RNA - urinary bladder [nTPM]":"23.8","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"45.4","Cell RNA - A-431 [nTPM]":"74.9","Cell RNA - A549 [nTPM]":"36.1","Cell RNA - AF22 [nTPM]":"41.2","Cell RNA - AN3-CA [nTPM]":"12.7","Cell RNA - ASC diff [nTPM]":"68.9","Cell RNA - ASC TERT1 [nTPM]":"54.6","Cell RNA - BEWO [nTPM]":"40.5","Cell RNA - BJ [nTPM]":"49.7","Cell RNA - BJ hTERT+ [nTPM]":"22.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"37.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.5","Cell RNA - CACO-2 [nTPM]":"37.6","Cell RNA - CAPAN-2 [nTPM]":"93.4","Cell RNA - Daudi [nTPM]":"38.1","Cell RNA - EFO-21 [nTPM]":"32.8","Cell RNA - fHDF\/TERT166 [nTPM]":"45.6","Cell RNA - GAMG [nTPM]":"42.2","Cell RNA - HaCaT [nTPM]":"26.1","Cell RNA - HAP1 [nTPM]":"59.1","Cell RNA - HBEC3-KT [nTPM]":"35.0","Cell RNA - HBF TERT88 [nTPM]":"45.4","Cell RNA - HDLM-2 [nTPM]":"508.3","Cell RNA - HEK 293 [nTPM]":"72.8","Cell RNA - HEL [nTPM]":"104.7","Cell RNA - HeLa [nTPM]":"28.7","Cell RNA - Hep G2 [nTPM]":"42.9","Cell RNA - HHSteC [nTPM]":"41.1","Cell RNA - HL-60 [nTPM]":"39.8","Cell RNA - HMC-1 [nTPM]":"55.7","Cell RNA - HSkMC [nTPM]":"35.5","Cell RNA - hTCEpi [nTPM]":"58.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"41.2","Cell RNA - hTERT-HME1 [nTPM]":"45.3","Cell RNA - hTERT-RPE1 [nTPM]":"47.0","Cell RNA - HUVEC TERT2 [nTPM]":"26.2","Cell RNA - JURKAT [nTPM]":"62.1","Cell RNA - K-562 [nTPM]":"105.4","Cell RNA - Karpas-707 [nTPM]":"63.3","Cell RNA - LHCN-M2 [nTPM]":"48.6","Cell RNA - MCF7 [nTPM]":"30.2","Cell RNA - MOLT-4 [nTPM]":"106.9","Cell RNA - NB-4 [nTPM]":"11.4","Cell RNA - NTERA-2 [nTPM]":"9.3","Cell RNA - OE19 [nTPM]":"36.3","Cell RNA - PC-3 [nTPM]":"83.4","Cell RNA - REH [nTPM]":"79.6","Cell RNA - RH-30 [nTPM]":"57.1","Cell RNA - RPMI-8226 [nTPM]":"37.3","Cell RNA - RPTEC TERT1 [nTPM]":"35.3","Cell RNA - RT4 [nTPM]":"25.2","Cell RNA - SCLC-21H [nTPM]":"33.8","Cell RNA - SH-SY5Y [nTPM]":"66.0","Cell RNA - SiHa [nTPM]":"32.7","Cell RNA - SK-BR-3 [nTPM]":"42.5","Cell RNA - SK-MEL-30 [nTPM]":"57.3","Cell RNA - SuSa [nTPM]":"17.8","Cell RNA - T-47d [nTPM]":"38.5","Cell RNA - THP-1 [nTPM]":"153.8","Cell RNA - TIME [nTPM]":"56.4","Cell RNA - U-138 MG [nTPM]":"41.4","Cell RNA - U-2 OS [nTPM]":"122.6","Cell RNA - U-2197 [nTPM]":"99.6","Cell RNA - U-251 MG [nTPM]":"67.6","Cell RNA - U-266\/70 [nTPM]":"76.1","Cell RNA - U-266\/84 [nTPM]":"110.8","Cell RNA - U-698 [nTPM]":"83.1","Cell RNA - U-87 MG [nTPM]":"59.5","Cell RNA - U-937 [nTPM]":"583.9","Cell RNA - WM-115 [nTPM]":"27.4","Blood RNA - basophil [nTPM]":"15.1","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"2.5","Blood RNA - gdT-cell [nTPM]":"5.2","Blood RNA - intermediate monocyte [nTPM]":"3.0","Blood RNA - MAIT T-cell [nTPM]":"7.0","Blood RNA - memory B-cell [nTPM]":"4.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.3","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"5.2","Blood RNA - non-classical monocyte [nTPM]":"2.1","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"26.6","Brain RNA - basal ganglia [nTPM]":"35.1","Brain RNA - cerebellum [nTPM]":"29.9","Brain RNA - cerebral cortex [nTPM]":"42.4","Brain RNA - hippocampal formation [nTPM]":"25.0","Brain RNA - hypothalamus [nTPM]":"27.8","Brain RNA - medulla oblongata [nTPM]":"29.5","Brain RNA - midbrain [nTPM]":"30.1","Brain RNA - pons [nTPM]":"31.6","Brain RNA - spinal cord [nTPM]":"29.9","Brain RNA - thalamus [nTPM]":"28.1","Brain RNA - white matter [nTPM]":"45.4","Single Cell Type RNA - Adipocytes [nTPM]":"18.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"23.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"20.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"19.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.7","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.3","Single Cell Type RNA - Early spermatids [nTPM]":"134.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.3","Single Cell Type RNA - Endothelial cells [nTPM]":"24.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.2","Single Cell Type RNA - Erythroid cells [nTPM]":"19.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"22.2","Single Cell Type RNA - Fibroblasts [nTPM]":"19.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.8","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"12.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"30.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.9","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.9","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"19.7","Single Cell Type RNA - Langerhans cells [nTPM]":"25.6","Single Cell Type RNA - Late spermatids [nTPM]":"165.1","Single Cell Type RNA - Leydig cells [nTPM]":"36.1","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"17.5","Single Cell Type RNA - Muller glia cells [nTPM]":"13.9","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.9","Single Cell Type RNA - Paneth cells [nTPM]":"7.3","Single Cell Type RNA - Peritubular cells [nTPM]":"36.5","Single Cell Type RNA - Plasma cells [nTPM]":"33.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.2","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.6","Single Cell Type RNA - Spermatocytes [nTPM]":"19.8","Single Cell Type RNA - Spermatogonia [nTPM]":"22.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.7","Single Cell Type RNA - T-cells [nTPM]":"22.4","Single Cell Type RNA - Theca cells [nTPM]":"17.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.3","Single Cell Type RNA - Urothelial cells [nTPM]":"20.4"},{"Gene":"BRAF","Gene synonym":["BRAF1"],"Ensembl":"ENSG00000157764","Gene description":"B-Raf proto-oncogene, serine\/threonine kinase","Uniprot":["P15056"],"Chromosome":"7","Position":"140719327-140924929","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Allosteric enzyme","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Deafness","Disease variant","Ectodermal dysplasia","FDA approved drug targets","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"252.3","Inhibitory neurons":"242.4","Oligodendrocyte precursor cells":"206.1","Oligodendrocytes":"202.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001328","CAB004552","HPA071048"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004552":"AB_626760","HPA001328":"AB_1078296","HPA071048":"AB_2686336"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.66e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.07e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"5.8","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"7.7","Tissue RNA - bone marrow [nTPM]":"15.9","Tissue RNA - breast [nTPM]":"8.8","Tissue RNA - cerebellum [nTPM]":"12.5","Tissue RNA - cerebral cortex [nTPM]":"8.7","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"5.4","Tissue RNA - colon [nTPM]":"8.6","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"8.3","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"7.6","Tissue RNA - hippocampal formation [nTPM]":"8.3","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"7.6","Tissue RNA - liver [nTPM]":"6.6","Tissue RNA - lung [nTPM]":"9.9","Tissue RNA - lymph node [nTPM]":"6.9","Tissue RNA - medulla oblongata [nTPM]":"4.0","Tissue RNA - midbrain [nTPM]":"3.6","Tissue RNA - ovary [nTPM]":"9.8","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"8.2","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"17.0","Tissue RNA - salivary gland [nTPM]":"7.2","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"6.0","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"6.7","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"13.7","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"10.2","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"6.4","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"6.7","Cell RNA - A-431 [nTPM]":"6.3","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"7.7","Cell RNA - AN3-CA [nTPM]":"9.4","Cell RNA - ASC diff [nTPM]":"9.1","Cell RNA - ASC TERT1 [nTPM]":"11.8","Cell RNA - BEWO [nTPM]":"12.3","Cell RNA - BJ [nTPM]":"6.8","Cell RNA - BJ hTERT+ [nTPM]":"7.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"7.6","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"6.7","Cell RNA - Daudi [nTPM]":"10.8","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"8.4","Cell RNA - HaCaT [nTPM]":"3.4","Cell RNA - HAP1 [nTPM]":"6.8","Cell RNA - HBEC3-KT [nTPM]":"5.5","Cell RNA - HBF TERT88 [nTPM]":"10.0","Cell RNA - HDLM-2 [nTPM]":"9.8","Cell RNA - HEK 293 [nTPM]":"5.4","Cell RNA - HEL [nTPM]":"7.1","Cell RNA - HeLa [nTPM]":"5.1","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"7.6","Cell RNA - HL-60 [nTPM]":"11.7","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"7.9","Cell RNA - hTCEpi [nTPM]":"6.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"12.0","Cell RNA - hTERT-RPE1 [nTPM]":"8.2","Cell RNA - HUVEC TERT2 [nTPM]":"6.6","Cell RNA - JURKAT [nTPM]":"7.7","Cell RNA - K-562 [nTPM]":"11.3","Cell RNA - Karpas-707 [nTPM]":"19.1","Cell RNA - LHCN-M2 [nTPM]":"9.8","Cell RNA - MCF7 [nTPM]":"3.3","Cell RNA - MOLT-4 [nTPM]":"15.6","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"10.1","Cell RNA - RH-30 [nTPM]":"6.5","Cell RNA - RPMI-8226 [nTPM]":"8.9","Cell RNA - RPTEC TERT1 [nTPM]":"5.3","Cell RNA - RT4 [nTPM]":"11.9","Cell RNA - SCLC-21H [nTPM]":"8.9","Cell RNA - SH-SY5Y [nTPM]":"7.3","Cell RNA - SiHa [nTPM]":"7.9","Cell RNA - SK-BR-3 [nTPM]":"4.9","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"7.5","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"7.8","Cell RNA - TIME [nTPM]":"9.7","Cell RNA - U-138 MG [nTPM]":"5.9","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"12.9","Cell RNA - U-251 MG [nTPM]":"5.5","Cell RNA - U-266\/70 [nTPM]":"21.6","Cell RNA - U-266\/84 [nTPM]":"12.9","Cell RNA - U-698 [nTPM]":"16.7","Cell RNA - U-87 MG [nTPM]":"9.7","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"6.6","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"4.1","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.9","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"3.5","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"7.7","Brain RNA - cerebellum [nTPM]":"12.5","Brain RNA - cerebral cortex [nTPM]":"8.7","Brain RNA - hippocampal formation [nTPM]":"8.3","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"4.0","Brain RNA - midbrain [nTPM]":"3.6","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.7","Single Cell Type RNA - Adipocytes [nTPM]":"43.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.7","Single Cell Type RNA - Astrocytes [nTPM]":"151.1","Single Cell Type RNA - B-cells [nTPM]":"58.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"29.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"19.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"18.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - dendritic cells [nTPM]":"73.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.3","Single Cell Type RNA - Early spermatids [nTPM]":"68.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.4","Single Cell Type RNA - Endothelial cells [nTPM]":"23.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"14.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"252.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"22.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"69.2","Single Cell Type RNA - granulocytes [nTPM]":"24.7","Single Cell Type RNA - Granulosa cells [nTPM]":"45.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"9.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"242.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.8","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.6","Single Cell Type RNA - Langerhans cells [nTPM]":"37.1","Single Cell Type RNA - Late spermatids [nTPM]":"36.5","Single Cell Type RNA - Leydig cells [nTPM]":"16.4","Single Cell Type RNA - Macrophages [nTPM]":"30.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"126.5","Single Cell Type RNA - monocytes [nTPM]":"14.6","Single Cell Type RNA - Muller glia cells [nTPM]":"11.3","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"206.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"202.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.4","Single Cell Type RNA - Paneth cells [nTPM]":"8.1","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"48.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.7","Single Cell Type RNA - Spermatocytes [nTPM]":"43.8","Single Cell Type RNA - Spermatogonia [nTPM]":"26.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.5","Single Cell Type RNA - T-cells [nTPM]":"41.4","Single Cell Type RNA - Theca cells [nTPM]":"30.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.7","Single Cell Type RNA - Urothelial cells [nTPM]":"33.4"},{"Gene":"BRCA1","Gene synonym":["BRCC1","FANCS","PPP1R53","RNF53"],"Ensembl":"ENSG00000012048","Gene description":"BRCA1 DNA repair associated","Uniprot":["P38398"],"Chromosome":"17","Position":"43044295-43170245","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA recombination","DNA repair","Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Activator","DNA-binding","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"42.5","Granulosa cells":"38.2","Spermatocytes":"105.8","Spermatogonia":"73.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"6.8","classical monocyte":"14.7","intermediate monocyte":"4.7","myeloid DC":"10.9","neutrophil":"11.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"10.9","granulocytes":"11.3","monocytes":"14.7"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001946","HPA004840","HPA034966","HPA057371"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB001946":null,"HPA004840":null,"HPA034966":"AB_10795287","HPA057371":"AB_2732611"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.87e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.07e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"3.1","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"4.2","Tissue RNA - appendix [nTPM]":"7.5","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"13.0","Tissue RNA - breast [nTPM]":"3.6","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"5.2","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"3.7","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"3.0","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"4.1","Tissue RNA - kidney [nTPM]":"2.0","Tissue RNA - liver [nTPM]":"5.6","Tissue RNA - lung [nTPM]":"3.2","Tissue RNA - lymph node [nTPM]":"10.3","Tissue RNA - medulla oblongata [nTPM]":"5.6","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"2.8","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"7.4","Tissue RNA - retina [nTPM]":"8.2","Tissue RNA - salivary gland [nTPM]":"3.2","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"4.2","Tissue RNA - skin 1 [nTPM]":"6.0","Tissue RNA - small intestine [nTPM]":"5.1","Tissue RNA - smooth muscle [nTPM]":"3.9","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"3.9","Tissue RNA - stomach 1 [nTPM]":"3.6","Tissue RNA - testis [nTPM]":"13.0","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"14.5","Tissue RNA - thyroid gland [nTPM]":"7.8","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"2.8","Tissue RNA - vagina [nTPM]":"2.4","Tissue RNA - white matter [nTPM]":"10.8","Cell RNA - A-431 [nTPM]":"44.1","Cell RNA - A549 [nTPM]":"69.1","Cell RNA - AF22 [nTPM]":"37.8","Cell RNA - AN3-CA [nTPM]":"30.1","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"13.4","Cell RNA - BEWO [nTPM]":"36.6","Cell RNA - BJ [nTPM]":"50.6","Cell RNA - BJ hTERT+ [nTPM]":"21.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"41.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.3","Cell RNA - CACO-2 [nTPM]":"42.3","Cell RNA - CAPAN-2 [nTPM]":"33.4","Cell RNA - Daudi [nTPM]":"100.8","Cell RNA - EFO-21 [nTPM]":"9.1","Cell RNA - fHDF\/TERT166 [nTPM]":"19.0","Cell RNA - GAMG [nTPM]":"49.0","Cell RNA - HaCaT [nTPM]":"49.5","Cell RNA - HAP1 [nTPM]":"51.9","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"69.5","Cell RNA - HDLM-2 [nTPM]":"46.9","Cell RNA - HEK 293 [nTPM]":"38.0","Cell RNA - HEL [nTPM]":"48.1","Cell RNA - HeLa [nTPM]":"54.0","Cell RNA - Hep G2 [nTPM]":"37.1","Cell RNA - HHSteC [nTPM]":"1.3","Cell RNA - HL-60 [nTPM]":"86.0","Cell RNA - HMC-1 [nTPM]":"39.9","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"63.1","Cell RNA - hTERT-HME1 [nTPM]":"20.0","Cell RNA - hTERT-RPE1 [nTPM]":"10.6","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"46.6","Cell RNA - K-562 [nTPM]":"73.7","Cell RNA - Karpas-707 [nTPM]":"42.2","Cell RNA - LHCN-M2 [nTPM]":"39.7","Cell RNA - MCF7 [nTPM]":"30.0","Cell RNA - MOLT-4 [nTPM]":"72.0","Cell RNA - NB-4 [nTPM]":"27.8","Cell RNA - NTERA-2 [nTPM]":"20.5","Cell RNA - OE19 [nTPM]":"29.1","Cell RNA - PC-3 [nTPM]":"18.7","Cell RNA - REH [nTPM]":"49.0","Cell RNA - RH-30 [nTPM]":"79.8","Cell RNA - RPMI-8226 [nTPM]":"40.8","Cell RNA - RPTEC TERT1 [nTPM]":"15.4","Cell RNA - RT4 [nTPM]":"42.1","Cell RNA - SCLC-21H [nTPM]":"25.8","Cell RNA - SH-SY5Y [nTPM]":"27.4","Cell RNA - SiHa [nTPM]":"38.8","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"19.4","Cell RNA - SuSa [nTPM]":"25.5","Cell RNA - T-47d [nTPM]":"33.9","Cell RNA - THP-1 [nTPM]":"39.6","Cell RNA - TIME [nTPM]":"13.8","Cell RNA - U-138 MG [nTPM]":"37.2","Cell RNA - U-2 OS [nTPM]":"29.6","Cell RNA - U-2197 [nTPM]":"49.0","Cell RNA - U-251 MG [nTPM]":"53.2","Cell RNA - U-266\/70 [nTPM]":"20.1","Cell RNA - U-266\/84 [nTPM]":"51.2","Cell RNA - U-698 [nTPM]":"75.5","Cell RNA - U-87 MG [nTPM]":"29.6","Cell RNA - U-937 [nTPM]":"49.6","Cell RNA - WM-115 [nTPM]":"39.4","Blood RNA - basophil [nTPM]":"6.8","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"2.2","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"1.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"10.9","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"11.3","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"17.5","Brain RNA - amygdala [nTPM]":"4.2","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"5.2","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"4.1","Brain RNA - medulla oblongata [nTPM]":"5.6","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"10.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.8","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"5.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"10.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.8","Single Cell Type RNA - dendritic cells [nTPM]":"8.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"11.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"4.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"42.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.2","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"38.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.3","Single Cell Type RNA - Hepatocytes [nTPM]":"18.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.1","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"3.9","Single Cell Type RNA - Langerhans cells [nTPM]":"2.8","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"2.5","Single Cell Type RNA - Macrophages [nTPM]":"6.4","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"4.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.7","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"16.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.5","Single Cell Type RNA - Spermatocytes [nTPM]":"105.8","Single Cell Type RNA - Spermatogonia [nTPM]":"73.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"4.7","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"BRCA2","Gene synonym":["BRCC2","FACD","FAD","FAD1","FANCD","FANCD1","XRCC11"],"Ensembl":"ENSG00000139618","Gene description":"BRCA2 DNA repair associated","Uniprot":["P51587"],"Chromosome":"13","Position":"32315086-32400268","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA recombination","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Fanconi anemia","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.8","lymphoid tissue":"3.1","testis":"2.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"115.4","Spermatogonia":"85.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA026815"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA026815":"AB_10602692"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"5.8","Tissue RNA - breast [nTPM]":"0.5","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.2","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"4.7","Cell RNA - A549 [nTPM]":"4.0","Cell RNA - AF22 [nTPM]":"6.0","Cell RNA - AN3-CA [nTPM]":"5.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"1.4","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"10.6","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"15.9","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.1","Cell RNA - GAMG [nTPM]":"7.6","Cell RNA - HaCaT [nTPM]":"6.1","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"2.9","Cell RNA - HBF TERT88 [nTPM]":"10.5","Cell RNA - HDLM-2 [nTPM]":"10.5","Cell RNA - HEK 293 [nTPM]":"3.1","Cell RNA - HEL [nTPM]":"10.3","Cell RNA - HeLa [nTPM]":"2.5","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"15.4","Cell RNA - HMC-1 [nTPM]":"4.9","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.3","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.4","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"8.1","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"5.1","Cell RNA - MOLT-4 [nTPM]":"11.8","Cell RNA - NB-4 [nTPM]":"8.3","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"4.9","Cell RNA - PC-3 [nTPM]":"2.3","Cell RNA - REH [nTPM]":"11.4","Cell RNA - RH-30 [nTPM]":"17.3","Cell RNA - RPMI-8226 [nTPM]":"3.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.4","Cell RNA - RT4 [nTPM]":"5.4","Cell RNA - SCLC-21H [nTPM]":"2.4","Cell RNA - SH-SY5Y [nTPM]":"4.6","Cell RNA - SiHa [nTPM]":"5.9","Cell RNA - SK-BR-3 [nTPM]":"2.4","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"2.9","Cell RNA - THP-1 [nTPM]":"7.3","Cell RNA - TIME [nTPM]":"1.3","Cell RNA - U-138 MG [nTPM]":"6.3","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"7.0","Cell RNA - U-251 MG [nTPM]":"6.7","Cell RNA - U-266\/70 [nTPM]":"2.0","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"8.0","Cell RNA - U-87 MG [nTPM]":"2.7","Cell RNA - U-937 [nTPM]":"5.7","Cell RNA - WM-115 [nTPM]":"5.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"1.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"3.0","Blood RNA - T-reg [nTPM]":"1.1","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"4.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"12.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.1","Single Cell Type RNA - dendritic cells [nTPM]":"10.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"29.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.7","Single Cell Type RNA - Fibroblasts [nTPM]":"5.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"26.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.5","Single Cell Type RNA - Langerhans cells [nTPM]":"11.0","Single Cell Type RNA - Late spermatids [nTPM]":"4.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"14.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"20.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.2","Single Cell Type RNA - Paneth cells [nTPM]":"1.8","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"27.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"115.4","Single Cell Type RNA - Spermatogonia [nTPM]":"85.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.5","Single Cell Type RNA - T-cells [nTPM]":"7.9","Single Cell Type RNA - Theca cells [nTPM]":"4.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.8","Single Cell Type RNA - Urothelial cells [nTPM]":"2.3"},{"Gene":"CADM1","Gene synonym":["BL2","IGSF4","IGSF4A","Necl-2","NECL2","RA175","ST17","SYNCAM","SYNCAM1","TSLC1"],"Ensembl":"ENSG00000182985","Gene description":"Cell adhesion molecule 1","Uniprot":["Q9BY67"],"Chromosome":"11","Position":"115169218-115504957","Protein class":["Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Cell adhesion","Differentiation","Host-virus interaction","Immunity","Spermatogenesis"],"Molecular function":["Developmental protein"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"287.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"464.8","Astrocytes":"980.7","Bipolar cells":"566.6","Muller glia cells":"489.9","Oligodendrocyte precursor cells":"676.5","Oligodendrocytes":"622.8","Rod photoreceptor cells":"759.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"8.0","myeloid DC":"8.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"8.1","T-cells":"8.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"294.7","WM-115":"187.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037266"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"220000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 56: Bipolar cells - Visual perception","Subcellular main location":["Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB037266":"AB_532287"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.32e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.61e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.22e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.1","Tissue RNA - adrenal gland [nTPM]":"29.9","Tissue RNA - amygdala [nTPM]":"46.9","Tissue RNA - appendix [nTPM]":"6.1","Tissue RNA - basal ganglia [nTPM]":"59.2","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"17.0","Tissue RNA - cerebellum [nTPM]":"78.7","Tissue RNA - cerebral cortex [nTPM]":"53.0","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"11.7","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"103.7","Tissue RNA - esophagus [nTPM]":"12.6","Tissue RNA - fallopian tube [nTPM]":"22.6","Tissue RNA - gallbladder [nTPM]":"12.1","Tissue RNA - heart muscle [nTPM]":"25.7","Tissue RNA - hippocampal formation [nTPM]":"47.6","Tissue RNA - hypothalamus [nTPM]":"57.4","Tissue RNA - kidney [nTPM]":"29.1","Tissue RNA - liver [nTPM]":"65.3","Tissue RNA - lung [nTPM]":"72.0","Tissue RNA - lymph node [nTPM]":"14.1","Tissue RNA - medulla oblongata [nTPM]":"41.1","Tissue RNA - midbrain [nTPM]":"40.1","Tissue RNA - ovary [nTPM]":"12.3","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"56.6","Tissue RNA - pituitary gland [nTPM]":"26.0","Tissue RNA - placenta [nTPM]":"37.9","Tissue RNA - pons [nTPM]":"44.6","Tissue RNA - prostate [nTPM]":"15.2","Tissue RNA - rectum [nTPM]":"8.1","Tissue RNA - retina [nTPM]":"287.7","Tissue RNA - salivary gland [nTPM]":"38.0","Tissue RNA - seminal vesicle [nTPM]":"28.0","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"8.6","Tissue RNA - spinal cord [nTPM]":"30.3","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"50.5","Tissue RNA - thalamus [nTPM]":"55.8","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"69.7","Tissue RNA - tongue [nTPM]":"8.1","Tissue RNA - tonsil [nTPM]":"14.6","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"4.8","Tissue RNA - white matter [nTPM]":"38.0","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"23.3","Cell RNA - AF22 [nTPM]":"25.6","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"24.1","Cell RNA - BJ hTERT+ [nTPM]":"41.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"294.7","Cell RNA - CAPAN-2 [nTPM]":"26.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"75.9","Cell RNA - fHDF\/TERT166 [nTPM]":"36.5","Cell RNA - GAMG [nTPM]":"25.2","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"4.8","Cell RNA - HBEC3-KT [nTPM]":"27.4","Cell RNA - HBF TERT88 [nTPM]":"2.0","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"38.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"7.8","Cell RNA - Hep G2 [nTPM]":"114.5","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"56.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"38.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"63.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.5","Cell RNA - HUVEC TERT2 [nTPM]":"1.1","Cell RNA - JURKAT [nTPM]":"17.3","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"2.7","Cell RNA - LHCN-M2 [nTPM]":"4.3","Cell RNA - MCF7 [nTPM]":"19.3","Cell RNA - MOLT-4 [nTPM]":"20.0","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"24.0","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"61.6","Cell RNA - RPTEC TERT1 [nTPM]":"44.8","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"50.2","Cell RNA - SH-SY5Y [nTPM]":"107.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"25.4","Cell RNA - SK-MEL-30 [nTPM]":"21.7","Cell RNA - SuSa [nTPM]":"102.4","Cell RNA - T-47d [nTPM]":"92.4","Cell RNA - THP-1 [nTPM]":"1.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"2.3","Cell RNA - U-2 OS [nTPM]":"44.9","Cell RNA - U-2197 [nTPM]":"23.3","Cell RNA - U-251 MG [nTPM]":"13.0","Cell RNA - U-266\/70 [nTPM]":"64.9","Cell RNA - U-266\/84 [nTPM]":"98.9","Cell RNA - U-698 [nTPM]":"18.7","Cell RNA - U-87 MG [nTPM]":"36.3","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"187.5","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.4","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"2.9","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"8.1","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"46.9","Brain RNA - basal ganglia [nTPM]":"59.2","Brain RNA - cerebellum [nTPM]":"78.7","Brain RNA - cerebral cortex [nTPM]":"53.0","Brain RNA - hippocampal formation [nTPM]":"47.6","Brain RNA - hypothalamus [nTPM]":"57.4","Brain RNA - medulla oblongata [nTPM]":"41.1","Brain RNA - midbrain [nTPM]":"40.1","Brain RNA - pons [nTPM]":"44.6","Brain RNA - spinal cord [nTPM]":"30.3","Brain RNA - thalamus [nTPM]":"55.8","Brain RNA - white matter [nTPM]":"38.0","Single Cell Type RNA - Adipocytes [nTPM]":"14.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"464.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"195.3","Single Cell Type RNA - Astrocytes [nTPM]":"980.7","Single Cell Type RNA - B-cells [nTPM]":"6.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"26.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"566.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"61.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"27.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"350.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"71.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"39.2","Single Cell Type RNA - Early spermatids [nTPM]":"189.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"88.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.0","Single Cell Type RNA - Endothelial cells [nTPM]":"10.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"301.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.0","Single Cell Type RNA - Fibroblasts [nTPM]":"13.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"126.9","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"36.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"45.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"36.8","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"310.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.1","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"8.5","Single Cell Type RNA - Langerhans cells [nTPM]":"20.9","Single Cell Type RNA - Late spermatids [nTPM]":"224.0","Single Cell Type RNA - Leydig cells [nTPM]":"5.9","Single Cell Type RNA - Macrophages [nTPM]":"14.2","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"60.0","Single Cell Type RNA - monocytes [nTPM]":"13.3","Single Cell Type RNA - Muller glia cells [nTPM]":"489.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"676.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"622.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"4.1","Single Cell Type RNA - Plasma cells [nTPM]":"88.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"759.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"55.2","Single Cell Type RNA - Spermatogonia [nTPM]":"23.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - T-cells [nTPM]":"8.1","Single Cell Type RNA - Theca cells [nTPM]":"5.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"13.5"},{"Gene":"CALR","Gene synonym":["cC1qR","CRT","FLJ26680","RO","SSA"],"Ensembl":"ENSG00000179218","Gene description":"Calreticulin","Uniprot":["P27797"],"Chromosome":"19","Position":"12938578-12944489","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chaperone"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1717.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB001513","HPA002242","CAB019952","CAB079775"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB001513":null,"CAB019952":"AB_2069792","CAB079775":"AB_303403","HPA002242":"AB_1078384"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.76e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"295.5","Tissue RNA - adrenal gland [nTPM]":"257.6","Tissue RNA - amygdala [nTPM]":"201.7","Tissue RNA - appendix [nTPM]":"352.9","Tissue RNA - basal ganglia [nTPM]":"213.4","Tissue RNA - bone marrow [nTPM]":"554.9","Tissue RNA - breast [nTPM]":"218.9","Tissue RNA - cerebellum [nTPM]":"238.0","Tissue RNA - cerebral cortex [nTPM]":"213.5","Tissue RNA - cervix [nTPM]":"256.3","Tissue RNA - choroid plexus [nTPM]":"324.0","Tissue RNA - colon [nTPM]":"304.6","Tissue RNA - duodenum [nTPM]":"287.3","Tissue RNA - endometrium 1 [nTPM]":"275.8","Tissue RNA - epididymis [nTPM]":"647.7","Tissue RNA - esophagus [nTPM]":"338.2","Tissue RNA - fallopian tube [nTPM]":"266.7","Tissue RNA - gallbladder [nTPM]":"164.1","Tissue RNA - heart muscle [nTPM]":"303.2","Tissue RNA - hippocampal formation [nTPM]":"203.5","Tissue RNA - hypothalamus [nTPM]":"239.7","Tissue RNA - kidney [nTPM]":"296.9","Tissue RNA - liver [nTPM]":"782.3","Tissue RNA - lung [nTPM]":"308.9","Tissue RNA - lymph node [nTPM]":"230.0","Tissue RNA - medulla oblongata [nTPM]":"260.4","Tissue RNA - midbrain [nTPM]":"230.1","Tissue RNA - ovary [nTPM]":"272.2","Tissue RNA - pancreas [nTPM]":"319.7","Tissue RNA - parathyroid gland [nTPM]":"292.2","Tissue RNA - pituitary gland [nTPM]":"284.5","Tissue RNA - placenta [nTPM]":"403.3","Tissue RNA - pons [nTPM]":"254.5","Tissue RNA - prostate [nTPM]":"277.9","Tissue RNA - rectum [nTPM]":"336.7","Tissue RNA - retina [nTPM]":"96.2","Tissue RNA - salivary gland [nTPM]":"299.3","Tissue RNA - seminal vesicle [nTPM]":"247.2","Tissue RNA - skeletal muscle [nTPM]":"119.8","Tissue RNA - skin 1 [nTPM]":"189.3","Tissue RNA - small intestine [nTPM]":"277.2","Tissue RNA - smooth muscle [nTPM]":"349.7","Tissue RNA - spinal cord [nTPM]":"237.7","Tissue RNA - spleen [nTPM]":"277.3","Tissue RNA - stomach 1 [nTPM]":"300.6","Tissue RNA - testis [nTPM]":"165.2","Tissue RNA - thalamus [nTPM]":"267.3","Tissue RNA - thymus [nTPM]":"245.3","Tissue RNA - thyroid gland [nTPM]":"702.9","Tissue RNA - tongue [nTPM]":"104.7","Tissue RNA - tonsil [nTPM]":"319.4","Tissue RNA - urinary bladder [nTPM]":"252.2","Tissue RNA - vagina [nTPM]":"236.6","Tissue RNA - white matter [nTPM]":"274.2","Cell RNA - A-431 [nTPM]":"1681.4","Cell RNA - A549 [nTPM]":"673.6","Cell RNA - AF22 [nTPM]":"832.5","Cell RNA - AN3-CA [nTPM]":"1984.9","Cell RNA - ASC diff [nTPM]":"1110.8","Cell RNA - ASC TERT1 [nTPM]":"861.5","Cell RNA - BEWO [nTPM]":"724.6","Cell RNA - BJ [nTPM]":"2075.3","Cell RNA - BJ hTERT+ [nTPM]":"1160.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"839.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1280.4","Cell RNA - CACO-2 [nTPM]":"1044.2","Cell RNA - CAPAN-2 [nTPM]":"1353.5","Cell RNA - Daudi [nTPM]":"1087.2","Cell RNA - EFO-21 [nTPM]":"1960.0","Cell RNA - fHDF\/TERT166 [nTPM]":"2528.4","Cell RNA - GAMG [nTPM]":"1064.5","Cell RNA - HaCaT [nTPM]":"672.1","Cell RNA - HAP1 [nTPM]":"906.1","Cell RNA - HBEC3-KT [nTPM]":"1476.5","Cell RNA - HBF TERT88 [nTPM]":"800.7","Cell RNA - HDLM-2 [nTPM]":"730.0","Cell RNA - HEK 293 [nTPM]":"588.1","Cell RNA - HEL [nTPM]":"894.3","Cell RNA - HeLa [nTPM]":"689.0","Cell RNA - Hep G2 [nTPM]":"1619.6","Cell RNA - HHSteC [nTPM]":"2667.5","Cell RNA - HL-60 [nTPM]":"3638.5","Cell RNA - HMC-1 [nTPM]":"1171.8","Cell RNA - HSkMC [nTPM]":"946.8","Cell RNA - hTCEpi [nTPM]":"638.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1222.3","Cell RNA - hTERT-HME1 [nTPM]":"957.7","Cell RNA - hTERT-RPE1 [nTPM]":"1472.5","Cell RNA - HUVEC TERT2 [nTPM]":"1507.8","Cell RNA - JURKAT [nTPM]":"743.1","Cell RNA - K-562 [nTPM]":"814.5","Cell RNA - Karpas-707 [nTPM]":"536.3","Cell RNA - LHCN-M2 [nTPM]":"911.7","Cell RNA - MCF7 [nTPM]":"1222.3","Cell RNA - MOLT-4 [nTPM]":"1040.0","Cell RNA - NB-4 [nTPM]":"2511.9","Cell RNA - NTERA-2 [nTPM]":"808.7","Cell RNA - OE19 [nTPM]":"952.0","Cell RNA - PC-3 [nTPM]":"970.1","Cell RNA - REH [nTPM]":"777.0","Cell RNA - RH-30 [nTPM]":"770.8","Cell RNA - RPMI-8226 [nTPM]":"1329.9","Cell RNA - RPTEC TERT1 [nTPM]":"1138.3","Cell RNA - RT4 [nTPM]":"846.9","Cell RNA - SCLC-21H [nTPM]":"312.4","Cell RNA - SH-SY5Y [nTPM]":"668.4","Cell RNA - SiHa [nTPM]":"1438.7","Cell RNA - SK-BR-3 [nTPM]":"769.8","Cell RNA - SK-MEL-30 [nTPM]":"472.6","Cell RNA - SuSa [nTPM]":"789.9","Cell RNA - T-47d [nTPM]":"1014.4","Cell RNA - THP-1 [nTPM]":"1558.9","Cell RNA - TIME [nTPM]":"1460.6","Cell RNA - U-138 MG [nTPM]":"1113.2","Cell RNA - U-2 OS [nTPM]":"666.2","Cell RNA - U-2197 [nTPM]":"1533.6","Cell RNA - U-251 MG [nTPM]":"938.3","Cell RNA - U-266\/70 [nTPM]":"644.3","Cell RNA - U-266\/84 [nTPM]":"569.7","Cell RNA - U-698 [nTPM]":"985.8","Cell RNA - U-87 MG [nTPM]":"1567.6","Cell RNA - U-937 [nTPM]":"1616.3","Cell RNA - WM-115 [nTPM]":"1258.1","Blood RNA - basophil [nTPM]":"67.5","Blood RNA - classical monocyte [nTPM]":"72.8","Blood RNA - eosinophil [nTPM]":"39.7","Blood RNA - gdT-cell [nTPM]":"172.8","Blood RNA - intermediate monocyte [nTPM]":"147.8","Blood RNA - MAIT T-cell [nTPM]":"119.3","Blood RNA - memory B-cell [nTPM]":"90.0","Blood RNA - memory CD4 T-cell [nTPM]":"99.7","Blood RNA - memory CD8 T-cell [nTPM]":"130.0","Blood RNA - myeloid DC [nTPM]":"76.3","Blood RNA - naive B-cell [nTPM]":"77.5","Blood RNA - naive CD4 T-cell [nTPM]":"73.0","Blood RNA - naive CD8 T-cell [nTPM]":"134.4","Blood RNA - neutrophil [nTPM]":"23.8","Blood RNA - NK-cell [nTPM]":"103.1","Blood RNA - non-classical monocyte [nTPM]":"122.7","Blood RNA - plasmacytoid DC [nTPM]":"215.6","Blood RNA - T-reg [nTPM]":"83.4","Blood RNA - total PBMC [nTPM]":"75.8","Brain RNA - amygdala [nTPM]":"201.7","Brain RNA - basal ganglia [nTPM]":"213.4","Brain RNA - cerebellum [nTPM]":"238.0","Brain RNA - cerebral cortex [nTPM]":"213.5","Brain RNA - hippocampal formation [nTPM]":"203.5","Brain RNA - hypothalamus [nTPM]":"239.7","Brain RNA - medulla oblongata [nTPM]":"260.4","Brain RNA - midbrain [nTPM]":"230.1","Brain RNA - pons [nTPM]":"254.5","Brain RNA - spinal cord [nTPM]":"237.7","Brain RNA - thalamus [nTPM]":"267.3","Brain RNA - white matter [nTPM]":"274.2","Single Cell Type RNA - Adipocytes [nTPM]":"385.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"147.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"160.7","Single Cell Type RNA - Astrocytes [nTPM]":"34.6","Single Cell Type RNA - B-cells [nTPM]":"385.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"261.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"336.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"217.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"221.4","Single Cell Type RNA - Bipolar cells [nTPM]":"76.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"214.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"140.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"163.0","Single Cell Type RNA - Club cells [nTPM]":"175.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"222.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"652.9","Single Cell Type RNA - dendritic cells [nTPM]":"515.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"524.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"64.6","Single Cell Type RNA - Ductal cells [nTPM]":"582.7","Single Cell Type RNA - Early spermatids [nTPM]":"27.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"206.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"364.2","Single Cell Type RNA - Endothelial cells [nTPM]":"305.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"353.6","Single Cell Type RNA - Erythroid cells [nTPM]":"266.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"285.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1717.5","Single Cell Type RNA - Fibroblasts [nTPM]":"422.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"289.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"348.2","Single Cell Type RNA - granulocytes [nTPM]":"207.4","Single Cell Type RNA - Granulosa cells [nTPM]":"341.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"312.7","Single Cell Type RNA - Hepatocytes [nTPM]":"612.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"789.3","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"595.1","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"208.8","Single Cell Type RNA - Langerhans cells [nTPM]":"433.2","Single Cell Type RNA - Late spermatids [nTPM]":"30.6","Single Cell Type RNA - Leydig cells [nTPM]":"318.7","Single Cell Type RNA - Macrophages [nTPM]":"378.4","Single Cell Type RNA - Melanocytes [nTPM]":"213.5","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"229.9","Single Cell Type RNA - Muller glia cells [nTPM]":"316.5","Single Cell Type RNA - NK-cells [nTPM]":"360.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"410.2","Single Cell Type RNA - Paneth cells [nTPM]":"462.8","Single Cell Type RNA - Peritubular cells [nTPM]":"311.1","Single Cell Type RNA - Plasma cells [nTPM]":"1059.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"426.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"377.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"182.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"147.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"167.7","Single Cell Type RNA - Sertoli cells [nTPM]":"203.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"224.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"328.9","Single Cell Type RNA - Spermatocytes [nTPM]":"276.1","Single Cell Type RNA - Spermatogonia [nTPM]":"306.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"245.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"213.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"964.4","Single Cell Type RNA - T-cells [nTPM]":"345.8","Single Cell Type RNA - Theca cells [nTPM]":"399.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"471.4","Single Cell Type RNA - Urothelial cells [nTPM]":"329.6"},{"Gene":"CARD11","Gene synonym":["BIMP3","CARMA1"],"Ensembl":"ENSG00000198286","Gene description":"Caspase recruitment domain family member 11","Uniprot":["Q9BXL7"],"Chromosome":"7","Position":"2906142-3043867","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"47.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"34.9","dendritic cells":"47.2","Microglial cells":"49.6","NK-cells":"28.8","Pancreatic endocrine cells":"24.9","Plasma cells":"26.7","T-cells":"28.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"plasmacytoid DC":"31.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"31.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"122.7","K-562":"50.1","RT4":"91.4","U-698":"108.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052984"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA052984":"AB_2682005"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.68e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.10e-4"},"Tissue RNA - adipose tissue [nTPM]":"1.3","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"21.8","Tissue RNA - basal ganglia [nTPM]":"1.5","Tissue RNA - bone marrow [nTPM]":"18.5","Tissue RNA - breast [nTPM]":"1.2","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"1.5","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"1.0","Tissue RNA - colon [nTPM]":"2.4","Tissue RNA - duodenum [nTPM]":"3.7","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"8.8","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"4.9","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"1.6","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"47.3","Tissue RNA - medulla oblongata [nTPM]":"4.2","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"1.4","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"2.3","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"3.3","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"18.3","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"3.0","Tissue RNA - spleen [nTPM]":"31.5","Tissue RNA - stomach 1 [nTPM]":"7.5","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"14.0","Tissue RNA - thymus [nTPM]":"20.9","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"29.5","Tissue RNA - urinary bladder [nTPM]":"17.1","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"4.6","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"32.4","Cell RNA - CAPAN-2 [nTPM]":"35.5","Cell RNA - Daudi [nTPM]":"122.7","Cell RNA - EFO-21 [nTPM]":"29.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"27.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"42.1","Cell RNA - HEK 293 [nTPM]":"1.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"3.1","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.8","Cell RNA - HUVEC TERT2 [nTPM]":"23.1","Cell RNA - JURKAT [nTPM]":"13.3","Cell RNA - K-562 [nTPM]":"50.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"4.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"44.9","Cell RNA - OE19 [nTPM]":"20.6","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"5.9","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"30.7","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"91.4","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"1.5","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"17.7","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"2.5","Cell RNA - TIME [nTPM]":"15.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"11.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"12.3","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"108.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"7.7","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"5.4","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"5.2","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"6.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.9","Blood RNA - naive CD8 T-cell [nTPM]":"5.3","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"5.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"31.4","Blood RNA - T-reg [nTPM]":"3.5","Blood RNA - total PBMC [nTPM]":"2.9","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"1.5","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"1.5","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"4.9","Brain RNA - medulla oblongata [nTPM]":"4.2","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"3.0","Brain RNA - thalamus [nTPM]":"14.0","Brain RNA - white matter [nTPM]":"4.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"34.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"47.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"8.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"28.6","Single Cell Type RNA - Theca cells [nTPM]":"4.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.1"},{"Gene":"CASR","Gene synonym":["FHH","GPRC2A","HHC","HHC1","NSHPT"],"Ensembl":"ENSG00000036828","Gene description":"Calcium sensing receptor","Uniprot":["P41180"],"Chromosome":"3","Position":"122183668-122291629","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","Epilepsy","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"parathyroid gland":"654.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"25.6","Alveolar cells type 2":"20.2","Cholangiocytes":"27.1","Distal tubular cells":"13.7","Enteroendocrine cells":"11.5","Granulosa cells":"20.7","Respiratory ciliated cells":"15.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific FPKM":{"pancreatic cancer":"5.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA039686","HPA050335"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039686":"AB_10673536","HPA050335":"AB_2681092"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.20e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.7","Tissue RNA - cerebral cortex [nTPM]":"1.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"4.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"22.4","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"0.6","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"9.6","Tissue RNA - parathyroid gland [nTPM]":"654.4","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.8","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.5","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"2.8","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"1.7","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.2","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"1.7","Brain RNA - cerebral cortex [nTPM]":"1.6","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"0.6","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"0.8","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"1.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"27.1","Single Cell Type RNA - Club cells [nTPM]":"5.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"4.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"20.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.9","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CBL","Gene synonym":["c-Cbl","CBL2","RNF55"],"Ensembl":"ENSG00000110395","Gene description":"Cbl proto-oncogene","Uniprot":["P22681"],"Chromosome":"11","Position":"119206298-119313926","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"8.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004350","HPA027956"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"67000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004350":"AB_2244054","HPA027956":"AB_10601094"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.75e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.85e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"5.6","Tissue RNA - appendix [nTPM]":"9.5","Tissue RNA - basal ganglia [nTPM]":"5.7","Tissue RNA - bone marrow [nTPM]":"8.5","Tissue RNA - breast [nTPM]":"5.6","Tissue RNA - cerebellum [nTPM]":"5.3","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"5.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"6.2","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"6.5","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"3.9","Tissue RNA - heart muscle [nTPM]":"4.1","Tissue RNA - hippocampal formation [nTPM]":"5.3","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"2.7","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"10.7","Tissue RNA - medulla oblongata [nTPM]":"5.8","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"3.7","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"6.1","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"6.4","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"4.0","Tissue RNA - rectum [nTPM]":"5.0","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"4.6","Tissue RNA - skeletal muscle [nTPM]":"2.5","Tissue RNA - skin 1 [nTPM]":"5.2","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"5.2","Tissue RNA - testis [nTPM]":"18.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"22.5","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"3.2","Tissue RNA - tonsil [nTPM]":"11.2","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"6.0","Cell RNA - A-431 [nTPM]":"10.7","Cell RNA - A549 [nTPM]":"7.6","Cell RNA - AF22 [nTPM]":"26.6","Cell RNA - AN3-CA [nTPM]":"16.7","Cell RNA - ASC diff [nTPM]":"7.8","Cell RNA - ASC TERT1 [nTPM]":"9.2","Cell RNA - BEWO [nTPM]":"16.0","Cell RNA - BJ [nTPM]":"11.2","Cell RNA - BJ hTERT+ [nTPM]":"11.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.2","Cell RNA - CACO-2 [nTPM]":"16.7","Cell RNA - CAPAN-2 [nTPM]":"12.6","Cell RNA - Daudi [nTPM]":"25.1","Cell RNA - EFO-21 [nTPM]":"10.0","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"21.7","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"18.4","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"22.7","Cell RNA - HDLM-2 [nTPM]":"14.8","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"26.4","Cell RNA - HeLa [nTPM]":"6.2","Cell RNA - Hep G2 [nTPM]":"5.1","Cell RNA - HHSteC [nTPM]":"9.5","Cell RNA - HL-60 [nTPM]":"30.3","Cell RNA - HMC-1 [nTPM]":"27.9","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"10.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.7","Cell RNA - hTERT-HME1 [nTPM]":"28.4","Cell RNA - hTERT-RPE1 [nTPM]":"11.1","Cell RNA - HUVEC TERT2 [nTPM]":"26.3","Cell RNA - JURKAT [nTPM]":"23.7","Cell RNA - K-562 [nTPM]":"21.7","Cell RNA - Karpas-707 [nTPM]":"9.9","Cell RNA - LHCN-M2 [nTPM]":"19.1","Cell RNA - MCF7 [nTPM]":"11.3","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"17.0","Cell RNA - NTERA-2 [nTPM]":"14.0","Cell RNA - OE19 [nTPM]":"9.2","Cell RNA - PC-3 [nTPM]":"8.8","Cell RNA - REH [nTPM]":"17.5","Cell RNA - RH-30 [nTPM]":"13.5","Cell RNA - RPMI-8226 [nTPM]":"4.6","Cell RNA - RPTEC TERT1 [nTPM]":"9.3","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"3.7","Cell RNA - SH-SY5Y [nTPM]":"11.3","Cell RNA - SiHa [nTPM]":"20.9","Cell RNA - SK-BR-3 [nTPM]":"8.8","Cell RNA - SK-MEL-30 [nTPM]":"7.3","Cell RNA - SuSa [nTPM]":"18.1","Cell RNA - T-47d [nTPM]":"9.4","Cell RNA - THP-1 [nTPM]":"24.8","Cell RNA - TIME [nTPM]":"22.8","Cell RNA - U-138 MG [nTPM]":"16.0","Cell RNA - U-2 OS [nTPM]":"11.5","Cell RNA - U-2197 [nTPM]":"11.6","Cell RNA - U-251 MG [nTPM]":"14.7","Cell RNA - U-266\/70 [nTPM]":"3.3","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"19.9","Cell RNA - U-87 MG [nTPM]":"6.7","Cell RNA - U-937 [nTPM]":"25.4","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"2.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"2.8","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.3","Blood RNA - neutrophil [nTPM]":"8.6","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"5.6","Brain RNA - basal ganglia [nTPM]":"5.7","Brain RNA - cerebellum [nTPM]":"5.3","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"5.3","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"5.8","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"6.0","Single Cell Type RNA - Adipocytes [nTPM]":"23.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.3","Single Cell Type RNA - Astrocytes [nTPM]":"23.5","Single Cell Type RNA - B-cells [nTPM]":"23.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Bipolar cells [nTPM]":"14.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"6.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - dendritic cells [nTPM]":"24.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.1","Single Cell Type RNA - Early spermatids [nTPM]":"28.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.6","Single Cell Type RNA - Endothelial cells [nTPM]":"23.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"38.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.5","Single Cell Type RNA - Fibroblasts [nTPM]":"9.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.8","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"20.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"20.0","Single Cell Type RNA - Hepatocytes [nTPM]":"3.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.0","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.9","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"59.1","Single Cell Type RNA - Langerhans cells [nTPM]":"43.2","Single Cell Type RNA - Late spermatids [nTPM]":"42.0","Single Cell Type RNA - Leydig cells [nTPM]":"7.8","Single Cell Type RNA - Macrophages [nTPM]":"41.2","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"46.8","Single Cell Type RNA - Muller glia cells [nTPM]":"13.2","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"11.6","Single Cell Type RNA - Peritubular cells [nTPM]":"12.8","Single Cell Type RNA - Plasma cells [nTPM]":"19.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.7","Single Cell Type RNA - Spermatocytes [nTPM]":"38.0","Single Cell Type RNA - Spermatogonia [nTPM]":"36.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"24.9","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.9"},{"Gene":"CCDC6","Gene synonym":["D10S170","H4","PTC","TPC","TST1"],"Ensembl":"ENSG00000108091","Gene description":"Coiled-coil domain containing 6","Uniprot":["Q16204"],"Chromosome":"10","Position":"59788747-59906556","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019049","HPA019051"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019049":"AB_1846163","HPA019051":"AB_1846164"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.98e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.11e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.95e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.9","Tissue RNA - adrenal gland [nTPM]":"12.2","Tissue RNA - amygdala [nTPM]":"21.1","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"23.4","Tissue RNA - bone marrow [nTPM]":"16.8","Tissue RNA - breast [nTPM]":"22.4","Tissue RNA - cerebellum [nTPM]":"10.2","Tissue RNA - cerebral cortex [nTPM]":"20.0","Tissue RNA - cervix [nTPM]":"23.4","Tissue RNA - choroid plexus [nTPM]":"8.5","Tissue RNA - colon [nTPM]":"23.5","Tissue RNA - duodenum [nTPM]":"22.8","Tissue RNA - endometrium 1 [nTPM]":"24.9","Tissue RNA - epididymis [nTPM]":"16.7","Tissue RNA - esophagus [nTPM]":"34.1","Tissue RNA - fallopian tube [nTPM]":"25.3","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"10.0","Tissue RNA - hippocampal formation [nTPM]":"24.9","Tissue RNA - hypothalamus [nTPM]":"21.4","Tissue RNA - kidney [nTPM]":"21.2","Tissue RNA - liver [nTPM]":"12.1","Tissue RNA - lung [nTPM]":"17.3","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"15.7","Tissue RNA - pancreas [nTPM]":"25.2","Tissue RNA - parathyroid gland [nTPM]":"17.9","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"13.2","Tissue RNA - pons [nTPM]":"17.4","Tissue RNA - prostate [nTPM]":"19.4","Tissue RNA - rectum [nTPM]":"19.8","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"29.0","Tissue RNA - seminal vesicle [nTPM]":"14.3","Tissue RNA - skeletal muscle [nTPM]":"17.3","Tissue RNA - skin 1 [nTPM]":"28.6","Tissue RNA - small intestine [nTPM]":"16.2","Tissue RNA - smooth muscle [nTPM]":"30.8","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"14.7","Tissue RNA - stomach 1 [nTPM]":"18.6","Tissue RNA - testis [nTPM]":"11.4","Tissue RNA - thalamus [nTPM]":"20.8","Tissue RNA - thymus [nTPM]":"12.1","Tissue RNA - thyroid gland [nTPM]":"18.3","Tissue RNA - tongue [nTPM]":"12.2","Tissue RNA - tonsil [nTPM]":"21.6","Tissue RNA - urinary bladder [nTPM]":"17.3","Tissue RNA - vagina [nTPM]":"23.1","Tissue RNA - white matter [nTPM]":"12.6","Cell RNA - A-431 [nTPM]":"42.9","Cell RNA - A549 [nTPM]":"38.0","Cell RNA - AF22 [nTPM]":"18.7","Cell RNA - AN3-CA [nTPM]":"41.9","Cell RNA - ASC diff [nTPM]":"27.8","Cell RNA - ASC TERT1 [nTPM]":"41.6","Cell RNA - BEWO [nTPM]":"37.9","Cell RNA - BJ [nTPM]":"20.6","Cell RNA - BJ hTERT+ [nTPM]":"27.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.7","Cell RNA - CACO-2 [nTPM]":"74.4","Cell RNA - CAPAN-2 [nTPM]":"81.8","Cell RNA - Daudi [nTPM]":"36.5","Cell RNA - EFO-21 [nTPM]":"30.2","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"11.7","Cell RNA - HaCaT [nTPM]":"61.7","Cell RNA - HAP1 [nTPM]":"37.7","Cell RNA - HBEC3-KT [nTPM]":"37.5","Cell RNA - HBF TERT88 [nTPM]":"30.0","Cell RNA - HDLM-2 [nTPM]":"55.1","Cell RNA - HEK 293 [nTPM]":"18.7","Cell RNA - HEL [nTPM]":"29.8","Cell RNA - HeLa [nTPM]":"29.1","Cell RNA - Hep G2 [nTPM]":"45.5","Cell RNA - HHSteC [nTPM]":"33.5","Cell RNA - HL-60 [nTPM]":"34.5","Cell RNA - HMC-1 [nTPM]":"26.9","Cell RNA - HSkMC [nTPM]":"30.3","Cell RNA - hTCEpi [nTPM]":"48.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"33.7","Cell RNA - hTERT-HME1 [nTPM]":"81.8","Cell RNA - hTERT-RPE1 [nTPM]":"28.3","Cell RNA - HUVEC TERT2 [nTPM]":"30.2","Cell RNA - JURKAT [nTPM]":"20.4","Cell RNA - K-562 [nTPM]":"22.6","Cell RNA - Karpas-707 [nTPM]":"22.7","Cell RNA - LHCN-M2 [nTPM]":"26.6","Cell RNA - MCF7 [nTPM]":"57.6","Cell RNA - MOLT-4 [nTPM]":"14.5","Cell RNA - NB-4 [nTPM]":"19.8","Cell RNA - NTERA-2 [nTPM]":"29.9","Cell RNA - OE19 [nTPM]":"40.1","Cell RNA - PC-3 [nTPM]":"25.6","Cell RNA - REH [nTPM]":"19.2","Cell RNA - RH-30 [nTPM]":"30.5","Cell RNA - RPMI-8226 [nTPM]":"23.0","Cell RNA - RPTEC TERT1 [nTPM]":"33.9","Cell RNA - RT4 [nTPM]":"36.2","Cell RNA - SCLC-21H [nTPM]":"19.0","Cell RNA - SH-SY5Y [nTPM]":"16.6","Cell RNA - SiHa [nTPM]":"26.1","Cell RNA - SK-BR-3 [nTPM]":"107.8","Cell RNA - SK-MEL-30 [nTPM]":"23.1","Cell RNA - SuSa [nTPM]":"24.1","Cell RNA - T-47d [nTPM]":"68.7","Cell RNA - THP-1 [nTPM]":"18.4","Cell RNA - TIME [nTPM]":"31.1","Cell RNA - U-138 MG [nTPM]":"18.8","Cell RNA - U-2 OS [nTPM]":"33.9","Cell RNA - U-2197 [nTPM]":"29.3","Cell RNA - U-251 MG [nTPM]":"34.9","Cell RNA - U-266\/70 [nTPM]":"12.0","Cell RNA - U-266\/84 [nTPM]":"14.9","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"29.6","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"11.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"2.3","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"5.0","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"21.1","Brain RNA - basal ganglia [nTPM]":"23.4","Brain RNA - cerebellum [nTPM]":"10.2","Brain RNA - cerebral cortex [nTPM]":"20.0","Brain RNA - hippocampal formation [nTPM]":"24.9","Brain RNA - hypothalamus [nTPM]":"21.4","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"17.4","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"20.8","Brain RNA - white matter [nTPM]":"12.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"99.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.9","Single Cell Type RNA - Astrocytes [nTPM]":"45.1","Single Cell Type RNA - B-cells [nTPM]":"41.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"95.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"70.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"51.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"46.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"37.8","Single Cell Type RNA - dendritic cells [nTPM]":"31.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"50.2","Single Cell Type RNA - Early spermatids [nTPM]":"27.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"105.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.6","Single Cell Type RNA - Endothelial cells [nTPM]":"22.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.0","Single Cell Type RNA - Erythroid cells [nTPM]":"25.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"83.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"65.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.8","Single Cell Type RNA - Fibroblasts [nTPM]":"27.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"134.5","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"45.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.2","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.1","Single Cell Type RNA - Horizontal cells [nTPM]":"16.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.9","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"40.7","Single Cell Type RNA - Langerhans cells [nTPM]":"35.3","Single Cell Type RNA - Late spermatids [nTPM]":"80.6","Single Cell Type RNA - Leydig cells [nTPM]":"24.5","Single Cell Type RNA - Macrophages [nTPM]":"36.4","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"23.0","Single Cell Type RNA - Muller glia cells [nTPM]":"11.5","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"50.2","Single Cell Type RNA - Paneth cells [nTPM]":"25.0","Single Cell Type RNA - Peritubular cells [nTPM]":"19.5","Single Cell Type RNA - Plasma cells [nTPM]":"26.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"52.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"48.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"22.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"92.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.0","Single Cell Type RNA - T-cells [nTPM]":"24.3","Single Cell Type RNA - Theca cells [nTPM]":"32.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.3","Single Cell Type RNA - Urothelial cells [nTPM]":"46.1"},{"Gene":"CCND1","Gene synonym":["BCL1","D11S287E","PRAD1","U21B31"],"Ensembl":"ENSG00000110092","Gene description":"Cyclin D1","Uniprot":["P24385"],"Chromosome":"11","Position":"69641156-69654474","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","DNA damage","Transcription","Transcription regulation"],"Molecular function":["Cyclin","Repressor"],"Disease involvement":["Cancer-related genes","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"499.7","Ductal cells":"504.0","Pancreatic endocrine cells":"622.1","Urothelial cells":"412.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"1.1"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"U-266\/70":"874.2","WM-115":"1239.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000024","HPA027802"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 1: Pancreatic cells - Digestion","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000024":"AB_563678","HPA027802":"AB_2672390"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.51e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.84e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.40e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-1"},"Tissue RNA - adipose tissue [nTPM]":"55.6","Tissue RNA - adrenal gland [nTPM]":"29.2","Tissue RNA - amygdala [nTPM]":"12.1","Tissue RNA - appendix [nTPM]":"10.0","Tissue RNA - basal ganglia [nTPM]":"14.6","Tissue RNA - bone marrow [nTPM]":"1.5","Tissue RNA - breast [nTPM]":"40.2","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"11.9","Tissue RNA - cervix [nTPM]":"17.0","Tissue RNA - choroid plexus [nTPM]":"33.4","Tissue RNA - colon [nTPM]":"19.8","Tissue RNA - duodenum [nTPM]":"22.7","Tissue RNA - endometrium 1 [nTPM]":"14.8","Tissue RNA - epididymis [nTPM]":"27.6","Tissue RNA - esophagus [nTPM]":"72.9","Tissue RNA - fallopian tube [nTPM]":"30.8","Tissue RNA - gallbladder [nTPM]":"19.5","Tissue RNA - heart muscle [nTPM]":"64.9","Tissue RNA - hippocampal formation [nTPM]":"10.8","Tissue RNA - hypothalamus [nTPM]":"14.6","Tissue RNA - kidney [nTPM]":"32.2","Tissue RNA - liver [nTPM]":"107.3","Tissue RNA - lung [nTPM]":"61.1","Tissue RNA - lymph node [nTPM]":"10.5","Tissue RNA - medulla oblongata [nTPM]":"17.5","Tissue RNA - midbrain [nTPM]":"15.5","Tissue RNA - ovary [nTPM]":"4.6","Tissue RNA - pancreas [nTPM]":"86.3","Tissue RNA - parathyroid gland [nTPM]":"82.7","Tissue RNA - pituitary gland [nTPM]":"25.7","Tissue RNA - placenta [nTPM]":"63.7","Tissue RNA - pons [nTPM]":"18.3","Tissue RNA - prostate [nTPM]":"53.3","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"30.4","Tissue RNA - seminal vesicle [nTPM]":"50.4","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"120.3","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"23.3","Tissue RNA - spinal cord [nTPM]":"15.9","Tissue RNA - spleen [nTPM]":"37.2","Tissue RNA - stomach 1 [nTPM]":"52.7","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"21.7","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"45.5","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"19.0","Tissue RNA - urinary bladder [nTPM]":"29.5","Tissue RNA - vagina [nTPM]":"43.9","Tissue RNA - white matter [nTPM]":"24.0","Cell RNA - A-431 [nTPM]":"467.3","Cell RNA - A549 [nTPM]":"183.0","Cell RNA - AF22 [nTPM]":"59.5","Cell RNA - AN3-CA [nTPM]":"1.8","Cell RNA - ASC diff [nTPM]":"178.3","Cell RNA - ASC TERT1 [nTPM]":"186.7","Cell RNA - BEWO [nTPM]":"127.4","Cell RNA - BJ [nTPM]":"717.5","Cell RNA - BJ hTERT+ [nTPM]":"264.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"82.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.6","Cell RNA - CACO-2 [nTPM]":"206.9","Cell RNA - CAPAN-2 [nTPM]":"349.9","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"317.6","Cell RNA - fHDF\/TERT166 [nTPM]":"375.5","Cell RNA - GAMG [nTPM]":"137.2","Cell RNA - HaCaT [nTPM]":"332.1","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"195.2","Cell RNA - HBF TERT88 [nTPM]":"146.0","Cell RNA - HDLM-2 [nTPM]":"1.2","Cell RNA - HEK 293 [nTPM]":"36.5","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"46.7","Cell RNA - Hep G2 [nTPM]":"211.7","Cell RNA - HHSteC [nTPM]":"43.3","Cell RNA - HL-60 [nTPM]":"3.3","Cell RNA - HMC-1 [nTPM]":"6.7","Cell RNA - HSkMC [nTPM]":"106.5","Cell RNA - hTCEpi [nTPM]":"37.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"116.0","Cell RNA - hTERT-HME1 [nTPM]":"44.0","Cell RNA - hTERT-RPE1 [nTPM]":"192.5","Cell RNA - HUVEC TERT2 [nTPM]":"142.1","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"1.3","Cell RNA - LHCN-M2 [nTPM]":"654.2","Cell RNA - MCF7 [nTPM]":"197.1","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"26.6","Cell RNA - NTERA-2 [nTPM]":"109.0","Cell RNA - OE19 [nTPM]":"190.7","Cell RNA - PC-3 [nTPM]":"198.3","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"187.9","Cell RNA - RPMI-8226 [nTPM]":"11.3","Cell RNA - RPTEC TERT1 [nTPM]":"379.4","Cell RNA - RT4 [nTPM]":"282.8","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"231.4","Cell RNA - SiHa [nTPM]":"9.2","Cell RNA - SK-BR-3 [nTPM]":"167.7","Cell RNA - SK-MEL-30 [nTPM]":"458.4","Cell RNA - SuSa [nTPM]":"143.5","Cell RNA - T-47d [nTPM]":"102.6","Cell RNA - THP-1 [nTPM]":"9.5","Cell RNA - TIME [nTPM]":"600.4","Cell RNA - U-138 MG [nTPM]":"399.5","Cell RNA - U-2 OS [nTPM]":"111.0","Cell RNA - U-2197 [nTPM]":"176.1","Cell RNA - U-251 MG [nTPM]":"496.2","Cell RNA - U-266\/70 [nTPM]":"874.2","Cell RNA - U-266\/84 [nTPM]":"559.4","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"341.6","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"1239.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.1","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"12.1","Brain RNA - basal ganglia [nTPM]":"14.6","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"11.9","Brain RNA - hippocampal formation [nTPM]":"10.8","Brain RNA - hypothalamus [nTPM]":"14.6","Brain RNA - medulla oblongata [nTPM]":"17.5","Brain RNA - midbrain [nTPM]":"15.5","Brain RNA - pons [nTPM]":"18.3","Brain RNA - spinal cord [nTPM]":"15.9","Brain RNA - thalamus [nTPM]":"21.7","Brain RNA - white matter [nTPM]":"24.0","Single Cell Type RNA - Adipocytes [nTPM]":"84.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"182.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"115.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"8.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"202.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"234.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"499.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"133.1","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"163.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"140.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"80.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"92.9","Single Cell Type RNA - Club cells [nTPM]":"271.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"125.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - dendritic cells [nTPM]":"2.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"31.3","Single Cell Type RNA - Ductal cells [nTPM]":"504.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"104.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"141.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"56.5","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"142.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.2","Single Cell Type RNA - Fibroblasts [nTPM]":"67.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"127.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"199.5","Single Cell Type RNA - granulocytes [nTPM]":"29.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"98.2","Single Cell Type RNA - Hepatocytes [nTPM]":"165.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"75.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"42.6","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"18.8","Single Cell Type RNA - Langerhans cells [nTPM]":"61.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"23.6","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"2.4","Single Cell Type RNA - Muller glia cells [nTPM]":"79.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"622.1","Single Cell Type RNA - Paneth cells [nTPM]":"118.0","Single Cell Type RNA - Peritubular cells [nTPM]":"57.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"262.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"57.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"85.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"131.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"184.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"23.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"292.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"351.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"8.8","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"82.2","Single Cell Type RNA - Urothelial cells [nTPM]":"412.6"},{"Gene":"CCND2","Gene synonym":[],"Ensembl":"ENSG00000118971","Gene description":"Cyclin D2","Uniprot":["P30279"],"Chromosome":"12","Position":"4269771-4305353","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Cyclin"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"354.3","Granulosa cells":"438.5","Langerhans cells":"255.3","Plasma cells":"371.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"152.4","HBEC3-KT":"136.6","HDLM-2":"238.8","Karpas-707":"287.9","RH-30":"202.7","RPMI-8226":"114.2"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049138","HPA054196"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA049138":"AB_2680650","HPA054196":"AB_2682412"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.82e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.52e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.76e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.0","Tissue RNA - adrenal gland [nTPM]":"52.6","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"20.3","Tissue RNA - breast [nTPM]":"13.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"26.9","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"40.8","Tissue RNA - duodenum [nTPM]":"17.4","Tissue RNA - endometrium 1 [nTPM]":"26.1","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"12.2","Tissue RNA - fallopian tube [nTPM]":"22.1","Tissue RNA - gallbladder [nTPM]":"2.7","Tissue RNA - heart muscle [nTPM]":"51.9","Tissue RNA - hippocampal formation [nTPM]":"14.4","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"9.7","Tissue RNA - liver [nTPM]":"1.9","Tissue RNA - lung [nTPM]":"17.2","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"9.6","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"14.2","Tissue RNA - pancreas [nTPM]":"24.5","Tissue RNA - parathyroid gland [nTPM]":"9.9","Tissue RNA - pituitary gland [nTPM]":"23.5","Tissue RNA - placenta [nTPM]":"12.9","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"20.7","Tissue RNA - rectum [nTPM]":"10.4","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"9.1","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"12.6","Tissue RNA - small intestine [nTPM]":"25.9","Tissue RNA - smooth muscle [nTPM]":"9.8","Tissue RNA - spinal cord [nTPM]":"7.8","Tissue RNA - spleen [nTPM]":"19.7","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"3.2","Tissue RNA - thyroid gland [nTPM]":"20.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"5.1","Tissue RNA - urinary bladder [nTPM]":"26.5","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"152.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"62.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"16.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"136.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"238.8","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"57.0","Cell RNA - HMC-1 [nTPM]":"12.6","Cell RNA - HSkMC [nTPM]":"23.8","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"97.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.8","Cell RNA - K-562 [nTPM]":"17.0","Cell RNA - Karpas-707 [nTPM]":"287.9","Cell RNA - LHCN-M2 [nTPM]":"6.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"52.8","Cell RNA - NTERA-2 [nTPM]":"50.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"202.7","Cell RNA - RPMI-8226 [nTPM]":"114.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"8.1","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"89.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"4.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"39.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"60.7","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"32.3","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"6.6","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"4.7","Blood RNA - gdT-cell [nTPM]":"11.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"17.1","Blood RNA - memory B-cell [nTPM]":"3.1","Blood RNA - memory CD4 T-cell [nTPM]":"16.3","Blood RNA - memory CD8 T-cell [nTPM]":"13.8","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"10.4","Blood RNA - naive CD8 T-cell [nTPM]":"12.1","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"9.4","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"13.6","Blood RNA - total PBMC [nTPM]":"6.8","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"14.4","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"9.6","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"7.8","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"23.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"46.6","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"82.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"106.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"73.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"174.2","Single Cell Type RNA - Bipolar cells [nTPM]":"7.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"354.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"37.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - dendritic cells [nTPM]":"128.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"110.8","Single Cell Type RNA - Endothelial cells [nTPM]":"35.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"64.8","Single Cell Type RNA - Erythroid cells [nTPM]":"37.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"68.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"123.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"55.8","Single Cell Type RNA - Granulosa cells [nTPM]":"438.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.6","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"147.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"11.9","Single Cell Type RNA - Langerhans cells [nTPM]":"255.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.3","Single Cell Type RNA - Leydig cells [nTPM]":"52.5","Single Cell Type RNA - Macrophages [nTPM]":"39.3","Single Cell Type RNA - Melanocytes [nTPM]":"39.2","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"9.8","Single Cell Type RNA - Muller glia cells [nTPM]":"170.0","Single Cell Type RNA - NK-cells [nTPM]":"89.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.7","Single Cell Type RNA - Paneth cells [nTPM]":"49.4","Single Cell Type RNA - Peritubular cells [nTPM]":"124.1","Single Cell Type RNA - Plasma cells [nTPM]":"371.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"112.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"39.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.3","Single Cell Type RNA - T-cells [nTPM]":"122.6","Single Cell Type RNA - Theca cells [nTPM]":"41.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"159.7","Single Cell Type RNA - Urothelial cells [nTPM]":"8.4"},{"Gene":"CCND3","Gene synonym":[],"Ensembl":"ENSG00000112576","Gene description":"Cyclin D3","Uniprot":["P30281"],"Chromosome":"6","Position":"41934934-42050357","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Cyclin"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"256.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"NK-cells":"555.1","Syncytiotrophoblasts":"236.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"696.3","REH":"651.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000116","HPA042871"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000116":null,"HPA042871":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.12e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.08e-6"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Tissue RNA - adipose tissue [nTPM]":"74.3","Tissue RNA - adrenal gland [nTPM]":"137.6","Tissue RNA - amygdala [nTPM]":"84.8","Tissue RNA - appendix [nTPM]":"63.1","Tissue RNA - basal ganglia [nTPM]":"84.6","Tissue RNA - bone marrow [nTPM]":"220.2","Tissue RNA - breast [nTPM]":"64.8","Tissue RNA - cerebellum [nTPM]":"80.0","Tissue RNA - cerebral cortex [nTPM]":"94.5","Tissue RNA - cervix [nTPM]":"36.9","Tissue RNA - choroid plexus [nTPM]":"78.4","Tissue RNA - colon [nTPM]":"45.6","Tissue RNA - duodenum [nTPM]":"40.6","Tissue RNA - endometrium 1 [nTPM]":"35.4","Tissue RNA - epididymis [nTPM]":"15.3","Tissue RNA - esophagus [nTPM]":"39.6","Tissue RNA - fallopian tube [nTPM]":"43.2","Tissue RNA - gallbladder [nTPM]":"34.4","Tissue RNA - heart muscle [nTPM]":"68.1","Tissue RNA - hippocampal formation [nTPM]":"86.2","Tissue RNA - hypothalamus [nTPM]":"88.6","Tissue RNA - kidney [nTPM]":"42.4","Tissue RNA - liver [nTPM]":"22.1","Tissue RNA - lung [nTPM]":"102.5","Tissue RNA - lymph node [nTPM]":"143.3","Tissue RNA - medulla oblongata [nTPM]":"87.4","Tissue RNA - midbrain [nTPM]":"82.5","Tissue RNA - ovary [nTPM]":"36.0","Tissue RNA - pancreas [nTPM]":"31.6","Tissue RNA - parathyroid gland [nTPM]":"23.7","Tissue RNA - pituitary gland [nTPM]":"33.3","Tissue RNA - placenta [nTPM]":"55.4","Tissue RNA - pons [nTPM]":"84.0","Tissue RNA - prostate [nTPM]":"50.4","Tissue RNA - rectum [nTPM]":"27.0","Tissue RNA - retina [nTPM]":"10.3","Tissue RNA - salivary gland [nTPM]":"50.4","Tissue RNA - seminal vesicle [nTPM]":"25.6","Tissue RNA - skeletal muscle [nTPM]":"18.2","Tissue RNA - skin 1 [nTPM]":"52.3","Tissue RNA - small intestine [nTPM]":"78.5","Tissue RNA - smooth muscle [nTPM]":"28.6","Tissue RNA - spinal cord [nTPM]":"79.7","Tissue RNA - spleen [nTPM]":"170.4","Tissue RNA - stomach 1 [nTPM]":"66.1","Tissue RNA - testis [nTPM]":"11.1","Tissue RNA - thalamus [nTPM]":"86.4","Tissue RNA - thymus [nTPM]":"256.6","Tissue RNA - thyroid gland [nTPM]":"58.7","Tissue RNA - tongue [nTPM]":"32.5","Tissue RNA - tonsil [nTPM]":"83.6","Tissue RNA - urinary bladder [nTPM]":"45.4","Tissue RNA - vagina [nTPM]":"44.3","Tissue RNA - white matter [nTPM]":"80.8","Cell RNA - A-431 [nTPM]":"67.7","Cell RNA - A549 [nTPM]":"242.2","Cell RNA - AF22 [nTPM]":"24.6","Cell RNA - AN3-CA [nTPM]":"54.8","Cell RNA - ASC diff [nTPM]":"43.7","Cell RNA - ASC TERT1 [nTPM]":"88.6","Cell RNA - BEWO [nTPM]":"286.1","Cell RNA - BJ [nTPM]":"77.1","Cell RNA - BJ hTERT+ [nTPM]":"43.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"77.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"57.1","Cell RNA - CACO-2 [nTPM]":"45.9","Cell RNA - CAPAN-2 [nTPM]":"29.7","Cell RNA - Daudi [nTPM]":"288.9","Cell RNA - EFO-21 [nTPM]":"127.8","Cell RNA - fHDF\/TERT166 [nTPM]":"51.9","Cell RNA - GAMG [nTPM]":"68.9","Cell RNA - HaCaT [nTPM]":"40.5","Cell RNA - HAP1 [nTPM]":"65.8","Cell RNA - HBEC3-KT [nTPM]":"93.4","Cell RNA - HBF TERT88 [nTPM]":"39.2","Cell RNA - HDLM-2 [nTPM]":"49.2","Cell RNA - HEK 293 [nTPM]":"43.4","Cell RNA - HEL [nTPM]":"458.8","Cell RNA - HeLa [nTPM]":"106.6","Cell RNA - Hep G2 [nTPM]":"37.3","Cell RNA - HHSteC [nTPM]":"94.9","Cell RNA - HL-60 [nTPM]":"75.9","Cell RNA - HMC-1 [nTPM]":"385.2","Cell RNA - HSkMC [nTPM]":"84.7","Cell RNA - hTCEpi [nTPM]":"59.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"76.0","Cell RNA - hTERT-HME1 [nTPM]":"27.9","Cell RNA - hTERT-RPE1 [nTPM]":"23.5","Cell RNA - HUVEC TERT2 [nTPM]":"96.6","Cell RNA - JURKAT [nTPM]":"188.3","Cell RNA - K-562 [nTPM]":"236.7","Cell RNA - Karpas-707 [nTPM]":"27.2","Cell RNA - LHCN-M2 [nTPM]":"111.6","Cell RNA - MCF7 [nTPM]":"92.0","Cell RNA - MOLT-4 [nTPM]":"696.3","Cell RNA - NB-4 [nTPM]":"354.6","Cell RNA - NTERA-2 [nTPM]":"10.9","Cell RNA - OE19 [nTPM]":"202.8","Cell RNA - PC-3 [nTPM]":"51.5","Cell RNA - REH [nTPM]":"651.8","Cell RNA - RH-30 [nTPM]":"96.3","Cell RNA - RPMI-8226 [nTPM]":"32.2","Cell RNA - RPTEC TERT1 [nTPM]":"179.1","Cell RNA - RT4 [nTPM]":"44.9","Cell RNA - SCLC-21H [nTPM]":"83.8","Cell RNA - SH-SY5Y [nTPM]":"21.8","Cell RNA - SiHa [nTPM]":"65.8","Cell RNA - SK-BR-3 [nTPM]":"83.3","Cell RNA - SK-MEL-30 [nTPM]":"38.6","Cell RNA - SuSa [nTPM]":"30.6","Cell RNA - T-47d [nTPM]":"51.5","Cell RNA - THP-1 [nTPM]":"288.4","Cell RNA - TIME [nTPM]":"162.9","Cell RNA - U-138 MG [nTPM]":"86.2","Cell RNA - U-2 OS [nTPM]":"47.9","Cell RNA - U-2197 [nTPM]":"74.7","Cell RNA - U-251 MG [nTPM]":"88.1","Cell RNA - U-266\/70 [nTPM]":"17.9","Cell RNA - U-266\/84 [nTPM]":"15.2","Cell RNA - U-698 [nTPM]":"458.5","Cell RNA - U-87 MG [nTPM]":"50.4","Cell RNA - U-937 [nTPM]":"157.6","Cell RNA - WM-115 [nTPM]":"53.3","Blood RNA - basophil [nTPM]":"1281.3","Blood RNA - classical monocyte [nTPM]":"246.3","Blood RNA - eosinophil [nTPM]":"725.1","Blood RNA - gdT-cell [nTPM]":"390.4","Blood RNA - intermediate monocyte [nTPM]":"294.4","Blood RNA - MAIT T-cell [nTPM]":"276.5","Blood RNA - memory B-cell [nTPM]":"127.1","Blood RNA - memory CD4 T-cell [nTPM]":"266.4","Blood RNA - memory CD8 T-cell [nTPM]":"318.1","Blood RNA - myeloid DC [nTPM]":"343.3","Blood RNA - naive B-cell [nTPM]":"180.8","Blood RNA - naive CD4 T-cell [nTPM]":"306.4","Blood RNA - naive CD8 T-cell [nTPM]":"328.3","Blood RNA - neutrophil [nTPM]":"339.3","Blood RNA - NK-cell [nTPM]":"333.2","Blood RNA - non-classical monocyte [nTPM]":"405.6","Blood RNA - plasmacytoid DC [nTPM]":"221.4","Blood RNA - T-reg [nTPM]":"193.0","Blood RNA - total PBMC [nTPM]":"635.4","Brain RNA - amygdala [nTPM]":"84.8","Brain RNA - basal ganglia [nTPM]":"84.6","Brain RNA - cerebellum [nTPM]":"80.0","Brain RNA - cerebral cortex [nTPM]":"94.5","Brain RNA - hippocampal formation [nTPM]":"86.2","Brain RNA - hypothalamus [nTPM]":"88.6","Brain RNA - medulla oblongata [nTPM]":"87.4","Brain RNA - midbrain [nTPM]":"82.5","Brain RNA - pons [nTPM]":"84.0","Brain RNA - spinal cord [nTPM]":"79.7","Brain RNA - thalamus [nTPM]":"86.4","Brain RNA - white matter [nTPM]":"80.8","Single Cell Type RNA - Adipocytes [nTPM]":"102.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"67.9","Single Cell Type RNA - Astrocytes [nTPM]":"31.0","Single Cell Type RNA - B-cells [nTPM]":"102.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"27.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"95.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"52.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.9","Single Cell Type RNA - Bipolar cells [nTPM]":"19.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"45.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"26.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"27.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"201.0","Single Cell Type RNA - dendritic cells [nTPM]":"227.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"66.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"29.4","Single Cell Type RNA - Ductal cells [nTPM]":"20.3","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"10.8","Single Cell Type RNA - Endothelial cells [nTPM]":"68.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"133.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"82.4","Single Cell Type RNA - Fibroblasts [nTPM]":"32.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.2","Single Cell Type RNA - granulocytes [nTPM]":"26.6","Single Cell Type RNA - Granulosa cells [nTPM]":"7.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"70.6","Single Cell Type RNA - Hepatocytes [nTPM]":"7.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.5","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"115.7","Single Cell Type RNA - Langerhans cells [nTPM]":"51.7","Single Cell Type RNA - Late spermatids [nTPM]":"9.4","Single Cell Type RNA - Leydig cells [nTPM]":"41.3","Single Cell Type RNA - Macrophages [nTPM]":"152.2","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"47.8","Single Cell Type RNA - monocytes [nTPM]":"79.0","Single Cell Type RNA - Muller glia cells [nTPM]":"40.8","Single Cell Type RNA - NK-cells [nTPM]":"555.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.9","Single Cell Type RNA - Paneth cells [nTPM]":"30.5","Single Cell Type RNA - Peritubular cells [nTPM]":"51.9","Single Cell Type RNA - Plasma cells [nTPM]":"48.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"40.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.2","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.9","Single Cell Type RNA - Spermatocytes [nTPM]":"4.3","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"21.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"236.6","Single Cell Type RNA - T-cells [nTPM]":"195.0","Single Cell Type RNA - Theca cells [nTPM]":"141.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.7","Single Cell Type RNA - Urothelial cells [nTPM]":"52.8"},{"Gene":"CCNE1","Gene synonym":["CCNE"],"Ensembl":"ENSG00000105173","Gene description":"Cyclin E1","Uniprot":["P24864"],"Chromosome":"19","Position":"29811991-29824312","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Cyclin"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"35.8","placenta":"30.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"14","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"1756.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"293.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000308","CAB016682","HPA018169"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000308":null,"CAB016682":"AB_1614564","HPA018169":"AB_1847384"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.35e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.89e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.97e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-16"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.2","Tissue RNA - adrenal gland [nTPM]":"5.7","Tissue RNA - amygdala [nTPM]":"1.9","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"35.8","Tissue RNA - breast [nTPM]":"0.8","Tissue RNA - cerebellum [nTPM]":"2.8","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"3.9","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"4.4","Tissue RNA - fallopian tube [nTPM]":"0.9","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"2.3","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.5","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"1.1","Tissue RNA - lymph node [nTPM]":"6.1","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"2.1","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"2.8","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"30.8","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"1.0","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"1.5","Tissue RNA - seminal vesicle [nTPM]":"1.4","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"4.1","Tissue RNA - small intestine [nTPM]":"2.5","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"4.2","Tissue RNA - stomach 1 [nTPM]":"2.1","Tissue RNA - testis [nTPM]":"12.1","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"4.5","Tissue RNA - thyroid gland [nTPM]":"1.6","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"3.0","Tissue RNA - vagina [nTPM]":"1.8","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"15.6","Cell RNA - A549 [nTPM]":"31.8","Cell RNA - AF22 [nTPM]":"24.3","Cell RNA - AN3-CA [nTPM]":"34.0","Cell RNA - ASC diff [nTPM]":"5.2","Cell RNA - ASC TERT1 [nTPM]":"6.0","Cell RNA - BEWO [nTPM]":"293.1","Cell RNA - BJ [nTPM]":"24.7","Cell RNA - BJ hTERT+ [nTPM]":"5.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.2","Cell RNA - CACO-2 [nTPM]":"33.0","Cell RNA - CAPAN-2 [nTPM]":"31.2","Cell RNA - Daudi [nTPM]":"13.3","Cell RNA - EFO-21 [nTPM]":"55.9","Cell RNA - fHDF\/TERT166 [nTPM]":"11.1","Cell RNA - GAMG [nTPM]":"14.0","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"28.8","Cell RNA - HBEC3-KT [nTPM]":"12.8","Cell RNA - HBF TERT88 [nTPM]":"15.2","Cell RNA - HDLM-2 [nTPM]":"41.9","Cell RNA - HEK 293 [nTPM]":"17.7","Cell RNA - HEL [nTPM]":"11.2","Cell RNA - HeLa [nTPM]":"30.0","Cell RNA - Hep G2 [nTPM]":"34.5","Cell RNA - HHSteC [nTPM]":"4.1","Cell RNA - HL-60 [nTPM]":"44.0","Cell RNA - HMC-1 [nTPM]":"28.7","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"7.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.8","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"13.3","Cell RNA - JURKAT [nTPM]":"13.2","Cell RNA - K-562 [nTPM]":"45.6","Cell RNA - Karpas-707 [nTPM]":"5.8","Cell RNA - LHCN-M2 [nTPM]":"16.8","Cell RNA - MCF7 [nTPM]":"24.4","Cell RNA - MOLT-4 [nTPM]":"24.5","Cell RNA - NB-4 [nTPM]":"13.0","Cell RNA - NTERA-2 [nTPM]":"40.1","Cell RNA - OE19 [nTPM]":"36.2","Cell RNA - PC-3 [nTPM]":"7.2","Cell RNA - REH [nTPM]":"36.2","Cell RNA - RH-30 [nTPM]":"28.6","Cell RNA - RPMI-8226 [nTPM]":"10.1","Cell RNA - RPTEC TERT1 [nTPM]":"8.4","Cell RNA - RT4 [nTPM]":"24.6","Cell RNA - SCLC-21H [nTPM]":"20.5","Cell RNA - SH-SY5Y [nTPM]":"17.4","Cell RNA - SiHa [nTPM]":"35.4","Cell RNA - SK-BR-3 [nTPM]":"42.7","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"35.4","Cell RNA - T-47d [nTPM]":"9.5","Cell RNA - THP-1 [nTPM]":"32.7","Cell RNA - TIME [nTPM]":"8.0","Cell RNA - U-138 MG [nTPM]":"25.0","Cell RNA - U-2 OS [nTPM]":"92.8","Cell RNA - U-2197 [nTPM]":"14.9","Cell RNA - U-251 MG [nTPM]":"16.9","Cell RNA - U-266\/70 [nTPM]":"24.1","Cell RNA - U-266\/84 [nTPM]":"18.2","Cell RNA - U-698 [nTPM]":"91.6","Cell RNA - U-87 MG [nTPM]":"13.8","Cell RNA - U-937 [nTPM]":"5.6","Cell RNA - WM-115 [nTPM]":"13.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.9","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.8","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.5","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"2.1","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"4.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"122.4","Single Cell Type RNA - dendritic cells [nTPM]":"3.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"14.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.1","Single Cell Type RNA - Endothelial cells [nTPM]":"1.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"30.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1756.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.4","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.0","Single Cell Type RNA - Langerhans cells [nTPM]":"2.5","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"4.2","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"2.2","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"18.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.4","Single Cell Type RNA - Spermatocytes [nTPM]":"25.0","Single Cell Type RNA - Spermatogonia [nTPM]":"17.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"115.7","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.9","Single Cell Type RNA - Urothelial cells [nTPM]":"3.5"},{"Gene":"CCNE2","Gene synonym":["CYCE2"],"Ensembl":"ENSG00000175305","Gene description":"Cyclin E2","Uniprot":["O96020"],"Chromosome":"8","Position":"94879770-94896678","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Cyclin"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"37.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"33.6","Oligodendrocytes":"34.5","Spermatocytes":"77.7","Spermatogonia":"26.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"5.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"101.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB007825","CAB019374"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB007825":"AB_598148","CAB019374":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.49e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.87e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.77e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"37.0","Tissue RNA - breast [nTPM]":"2.2","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"7.7","Tissue RNA - cervix [nTPM]":"1.7","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"3.6","Tissue RNA - endometrium 1 [nTPM]":"1.8","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"4.7","Tissue RNA - fallopian tube [nTPM]":"0.6","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1.4","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"5.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"9.9","Tissue RNA - midbrain [nTPM]":"8.1","Tissue RNA - ovary [nTPM]":"1.5","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"8.8","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"5.7","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"1.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"5.9","Tissue RNA - small intestine [nTPM]":"4.3","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"7.4","Tissue RNA - spleen [nTPM]":"2.3","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"15.1","Tissue RNA - thyroid gland [nTPM]":"1.7","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"9.6","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"47.2","Cell RNA - A549 [nTPM]":"6.2","Cell RNA - AF22 [nTPM]":"24.0","Cell RNA - AN3-CA [nTPM]":"15.0","Cell RNA - ASC diff [nTPM]":"2.9","Cell RNA - ASC TERT1 [nTPM]":"5.4","Cell RNA - BEWO [nTPM]":"16.5","Cell RNA - BJ [nTPM]":"47.3","Cell RNA - BJ hTERT+ [nTPM]":"16.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.9","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"20.6","Cell RNA - Daudi [nTPM]":"24.5","Cell RNA - EFO-21 [nTPM]":"31.4","Cell RNA - fHDF\/TERT166 [nTPM]":"20.3","Cell RNA - GAMG [nTPM]":"9.1","Cell RNA - HaCaT [nTPM]":"24.4","Cell RNA - HAP1 [nTPM]":"19.4","Cell RNA - HBEC3-KT [nTPM]":"17.5","Cell RNA - HBF TERT88 [nTPM]":"39.5","Cell RNA - HDLM-2 [nTPM]":"17.4","Cell RNA - HEK 293 [nTPM]":"17.5","Cell RNA - HEL [nTPM]":"49.5","Cell RNA - HeLa [nTPM]":"26.6","Cell RNA - Hep G2 [nTPM]":"4.2","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"20.2","Cell RNA - HMC-1 [nTPM]":"29.0","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.4","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"6.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.5","Cell RNA - JURKAT [nTPM]":"30.1","Cell RNA - K-562 [nTPM]":"21.7","Cell RNA - Karpas-707 [nTPM]":"101.5","Cell RNA - LHCN-M2 [nTPM]":"42.5","Cell RNA - MCF7 [nTPM]":"14.2","Cell RNA - MOLT-4 [nTPM]":"77.8","Cell RNA - NB-4 [nTPM]":"9.7","Cell RNA - NTERA-2 [nTPM]":"8.1","Cell RNA - OE19 [nTPM]":"37.4","Cell RNA - PC-3 [nTPM]":"14.1","Cell RNA - REH [nTPM]":"54.1","Cell RNA - RH-30 [nTPM]":"41.7","Cell RNA - RPMI-8226 [nTPM]":"11.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.1","Cell RNA - RT4 [nTPM]":"26.4","Cell RNA - SCLC-21H [nTPM]":"34.8","Cell RNA - SH-SY5Y [nTPM]":"14.5","Cell RNA - SiHa [nTPM]":"31.8","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"5.9","Cell RNA - SuSa [nTPM]":"3.0","Cell RNA - T-47d [nTPM]":"42.0","Cell RNA - THP-1 [nTPM]":"21.2","Cell RNA - TIME [nTPM]":"13.0","Cell RNA - U-138 MG [nTPM]":"30.7","Cell RNA - U-2 OS [nTPM]":"20.2","Cell RNA - U-2197 [nTPM]":"22.9","Cell RNA - U-251 MG [nTPM]":"42.8","Cell RNA - U-266\/70 [nTPM]":"19.1","Cell RNA - U-266\/84 [nTPM]":"21.1","Cell RNA - U-698 [nTPM]":"59.3","Cell RNA - U-87 MG [nTPM]":"24.8","Cell RNA - U-937 [nTPM]":"36.1","Cell RNA - WM-115 [nTPM]":"23.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"5.2","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"7.7","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"5.4","Brain RNA - medulla oblongata [nTPM]":"9.9","Brain RNA - midbrain [nTPM]":"8.1","Brain RNA - pons [nTPM]":"8.8","Brain RNA - spinal cord [nTPM]":"7.4","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"2.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.2","Single Cell Type RNA - dendritic cells [nTPM]":"7.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"6.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.8","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.9","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"34.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"14.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.3","Single Cell Type RNA - Spermatocytes [nTPM]":"77.7","Single Cell Type RNA - Spermatogonia [nTPM]":"26.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"7.5","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.8"},{"Gene":"CD58","Gene synonym":["LFA3"],"Ensembl":"ENSG00000116815","Gene description":"CD58 molecule","Uniprot":["P19256"],"Chromosome":"1","Position":"116514534-116571039","Protein class":["CD markers","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"144.1","Langerhans cells":"195.9","monocytes":"156.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"135.9"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6500000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 26: Respiratory epithelial cells - Mucosal defense","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.20e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.60e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"22.7","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"7.5","Tissue RNA - appendix [nTPM]":"24.8","Tissue RNA - basal ganglia [nTPM]":"8.2","Tissue RNA - bone marrow [nTPM]":"57.9","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"8.0","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"13.6","Tissue RNA - choroid plexus [nTPM]":"10.2","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"28.8","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"16.1","Tissue RNA - esophagus [nTPM]":"25.4","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"34.3","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"8.8","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"12.7","Tissue RNA - lung [nTPM]":"29.1","Tissue RNA - lymph node [nTPM]":"19.0","Tissue RNA - medulla oblongata [nTPM]":"9.2","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"7.0","Tissue RNA - parathyroid gland [nTPM]":"11.9","Tissue RNA - pituitary gland [nTPM]":"6.7","Tissue RNA - placenta [nTPM]":"16.9","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"29.0","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"20.7","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"8.7","Tissue RNA - skin 1 [nTPM]":"20.0","Tissue RNA - small intestine [nTPM]":"29.6","Tissue RNA - smooth muscle [nTPM]":"16.9","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"24.7","Tissue RNA - stomach 1 [nTPM]":"19.0","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"9.7","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"10.8","Tissue RNA - tonsil [nTPM]":"20.3","Tissue RNA - urinary bladder [nTPM]":"29.7","Tissue RNA - vagina [nTPM]":"19.7","Tissue RNA - white matter [nTPM]":"10.2","Cell RNA - A-431 [nTPM]":"36.4","Cell RNA - A549 [nTPM]":"20.5","Cell RNA - AF22 [nTPM]":"14.7","Cell RNA - AN3-CA [nTPM]":"14.2","Cell RNA - ASC diff [nTPM]":"24.4","Cell RNA - ASC TERT1 [nTPM]":"40.7","Cell RNA - BEWO [nTPM]":"9.3","Cell RNA - BJ [nTPM]":"18.2","Cell RNA - BJ hTERT+ [nTPM]":"31.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"30.2","Cell RNA - CACO-2 [nTPM]":"9.2","Cell RNA - CAPAN-2 [nTPM]":"68.4","Cell RNA - Daudi [nTPM]":"6.5","Cell RNA - EFO-21 [nTPM]":"33.2","Cell RNA - fHDF\/TERT166 [nTPM]":"31.8","Cell RNA - GAMG [nTPM]":"36.2","Cell RNA - HaCaT [nTPM]":"45.9","Cell RNA - HAP1 [nTPM]":"11.0","Cell RNA - HBEC3-KT [nTPM]":"31.4","Cell RNA - HBF TERT88 [nTPM]":"32.7","Cell RNA - HDLM-2 [nTPM]":"35.8","Cell RNA - HEK 293 [nTPM]":"12.8","Cell RNA - HEL [nTPM]":"32.8","Cell RNA - HeLa [nTPM]":"36.9","Cell RNA - Hep G2 [nTPM]":"12.9","Cell RNA - HHSteC [nTPM]":"15.5","Cell RNA - HL-60 [nTPM]":"45.8","Cell RNA - HMC-1 [nTPM]":"43.5","Cell RNA - HSkMC [nTPM]":"11.2","Cell RNA - hTCEpi [nTPM]":"41.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.9","Cell RNA - hTERT-HME1 [nTPM]":"23.0","Cell RNA - hTERT-RPE1 [nTPM]":"66.4","Cell RNA - HUVEC TERT2 [nTPM]":"17.9","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"29.4","Cell RNA - Karpas-707 [nTPM]":"135.9","Cell RNA - LHCN-M2 [nTPM]":"19.2","Cell RNA - MCF7 [nTPM]":"64.7","Cell RNA - MOLT-4 [nTPM]":"19.8","Cell RNA - NB-4 [nTPM]":"34.6","Cell RNA - NTERA-2 [nTPM]":"7.3","Cell RNA - OE19 [nTPM]":"53.7","Cell RNA - PC-3 [nTPM]":"22.3","Cell RNA - REH [nTPM]":"38.4","Cell RNA - RH-30 [nTPM]":"49.9","Cell RNA - RPMI-8226 [nTPM]":"8.6","Cell RNA - RPTEC TERT1 [nTPM]":"63.0","Cell RNA - RT4 [nTPM]":"29.4","Cell RNA - SCLC-21H [nTPM]":"4.9","Cell RNA - SH-SY5Y [nTPM]":"10.3","Cell RNA - SiHa [nTPM]":"36.6","Cell RNA - SK-BR-3 [nTPM]":"26.9","Cell RNA - SK-MEL-30 [nTPM]":"108.3","Cell RNA - SuSa [nTPM]":"15.1","Cell RNA - T-47d [nTPM]":"14.0","Cell RNA - THP-1 [nTPM]":"16.8","Cell RNA - TIME [nTPM]":"33.8","Cell RNA - U-138 MG [nTPM]":"22.3","Cell RNA - U-2 OS [nTPM]":"17.1","Cell RNA - U-2197 [nTPM]":"30.3","Cell RNA - U-251 MG [nTPM]":"47.2","Cell RNA - U-266\/70 [nTPM]":"20.6","Cell RNA - U-266\/84 [nTPM]":"39.4","Cell RNA - U-698 [nTPM]":"4.6","Cell RNA - U-87 MG [nTPM]":"51.3","Cell RNA - U-937 [nTPM]":"22.4","Cell RNA - WM-115 [nTPM]":"113.2","Blood RNA - basophil [nTPM]":"133.7","Blood RNA - classical monocyte [nTPM]":"50.6","Blood RNA - eosinophil [nTPM]":"89.8","Blood RNA - gdT-cell [nTPM]":"37.3","Blood RNA - intermediate monocyte [nTPM]":"51.0","Blood RNA - MAIT T-cell [nTPM]":"26.1","Blood RNA - memory B-cell [nTPM]":"20.7","Blood RNA - memory CD4 T-cell [nTPM]":"32.7","Blood RNA - memory CD8 T-cell [nTPM]":"31.7","Blood RNA - myeloid DC [nTPM]":"43.9","Blood RNA - naive B-cell [nTPM]":"9.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.2","Blood RNA - naive CD8 T-cell [nTPM]":"18.2","Blood RNA - neutrophil [nTPM]":"165.7","Blood RNA - NK-cell [nTPM]":"18.5","Blood RNA - non-classical monocyte [nTPM]":"64.4","Blood RNA - plasmacytoid DC [nTPM]":"5.0","Blood RNA - T-reg [nTPM]":"64.3","Blood RNA - total PBMC [nTPM]":"37.4","Brain RNA - amygdala [nTPM]":"7.5","Brain RNA - basal ganglia [nTPM]":"8.2","Brain RNA - cerebellum [nTPM]":"8.0","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"8.8","Brain RNA - medulla oblongata [nTPM]":"9.2","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"10.2","Single Cell Type RNA - Adipocytes [nTPM]":"52.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.5","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"23.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"144.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"28.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"63.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - dendritic cells [nTPM]":"40.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"48.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"39.4","Single Cell Type RNA - Early spermatids [nTPM]":"3.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.1","Single Cell Type RNA - Endothelial cells [nTPM]":"38.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"46.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.6","Single Cell Type RNA - Fibroblasts [nTPM]":"31.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.0","Single Cell Type RNA - granulocytes [nTPM]":"53.0","Single Cell Type RNA - Granulosa cells [nTPM]":"3.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"58.7","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.7","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"33.0","Single Cell Type RNA - Langerhans cells [nTPM]":"195.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"10.5","Single Cell Type RNA - Macrophages [nTPM]":"72.2","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"156.1","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"46.7","Single Cell Type RNA - Paneth cells [nTPM]":"41.7","Single Cell Type RNA - Peritubular cells [nTPM]":"11.7","Single Cell Type RNA - Plasma cells [nTPM]":"24.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"46.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"26.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"2.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"44.7","Single Cell Type RNA - Theca cells [nTPM]":"9.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"42.6"},{"Gene":"CD79A","Gene synonym":["IGA","MB-1"],"Ensembl":"ENSG00000105369","Gene description":"CD79a molecule","Uniprot":["P11912"],"Chromosome":"19","Position":"41877279-41881372","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"152.3","lymphoid tissue":"545.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"B-cells":"1186.4","Plasma cells":"956.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"38","RNA blood cell specific nTPM":{"memory B-cell":"1273.8","naive B-cell":"1457.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"40","RNA blood lineage specific nTPM":{"B-cells":"1457.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"22","RNA cell line specific nTPM":{"Daudi":"1598.7","REH":"491.0","U-698":"1366.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000019","HPA056444"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB000019":"AB_2244527","HPA056444":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.13e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.08e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"213.4","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"47.2","Tissue RNA - breast [nTPM]":"9.5","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"3.6","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"47.3","Tissue RNA - duodenum [nTPM]":"37.9","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"1.4","Tissue RNA - esophagus [nTPM]":"9.9","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"13.0","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"8.9","Tissue RNA - lymph node [nTPM]":"482.4","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"3.7","Tissue RNA - pancreas [nTPM]":"0.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"4.3","Tissue RNA - rectum [nTPM]":"28.9","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"28.5","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"152.3","Tissue RNA - smooth muscle [nTPM]":"2.2","Tissue RNA - spinal cord [nTPM]":"0.6","Tissue RNA - spleen [nTPM]":"286.5","Tissue RNA - stomach 1 [nTPM]":"76.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"0.2","Tissue RNA - thymus [nTPM]":"93.7","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"0.4","Tissue RNA - tonsil [nTPM]":"545.2","Tissue RNA - urinary bladder [nTPM]":"32.3","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"1.1","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"1598.7","Cell RNA - EFO-21 [nTPM]":"1.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.2","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.7","Cell RNA - HEL [nTPM]":"2.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"1.8","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"8.0","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"1.1","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"9.9","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"491.0","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.8","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"1.3","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"4.8","Cell RNA - TIME [nTPM]":"1.6","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"4.3","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.8","Cell RNA - U-266\/70 [nTPM]":"7.8","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"1366.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"52.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"12.4","Blood RNA - classical monocyte [nTPM]":"1.5","Blood RNA - eosinophil [nTPM]":"6.9","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.8","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"1273.8","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"1457.5","Blood RNA - naive CD4 T-cell [nTPM]":"4.9","Blood RNA - naive CD8 T-cell [nTPM]":"26.3","Blood RNA - neutrophil [nTPM]":"4.6","Blood RNA - NK-cell [nTPM]":"2.6","Blood RNA - non-classical monocyte [nTPM]":"4.3","Blood RNA - plasmacytoid DC [nTPM]":"36.3","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"62.7","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.6","Brain RNA - thalamus [nTPM]":"0.2","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1186.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"18.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"10.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"6.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"1.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"138.7","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"181.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"956.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"23.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CD79B","Gene synonym":["B29","IGB"],"Ensembl":"ENSG00000007312","Gene description":"CD79b molecule","Uniprot":["P40259"],"Chromosome":"17","Position":"63928740-63932336","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"266.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"B-cells":"491.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"memory B-cell":"1132.1","naive B-cell":"1505.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"1505.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"1060.0","REH":"350.2","U-698":"1475.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009178","CAB009751","HPA044107"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB009751":"AB_2275844","HPA009178":"AB_1078483","HPA044107":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.35e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"1.7","Tissue RNA - amygdala [nTPM]":"0.9","Tissue RNA - appendix [nTPM]":"70.5","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"54.6","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"7.7","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"1.4","Tissue RNA - epididymis [nTPM]":"1.6","Tissue RNA - esophagus [nTPM]":"2.6","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"12.3","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"4.7","Tissue RNA - liver [nTPM]":"3.4","Tissue RNA - lung [nTPM]":"4.9","Tissue RNA - lymph node [nTPM]":"266.7","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.7","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"25.3","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"2.5","Tissue RNA - rectum [nTPM]":"7.2","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"7.8","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"3.4","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"66.2","Tissue RNA - smooth muscle [nTPM]":"2.6","Tissue RNA - spinal cord [nTPM]":"0.9","Tissue RNA - spleen [nTPM]":"147.7","Tissue RNA - stomach 1 [nTPM]":"10.7","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"27.1","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"208.4","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"1.0","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.6","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1060.0","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.5","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"2.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.6","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"1.2","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"1.2","Cell RNA - Karpas-707 [nTPM]":"56.9","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.6","Cell RNA - NB-4 [nTPM]":"23.0","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"350.2","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"4.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.7","Cell RNA - SuSa [nTPM]":"5.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"1.7","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"3.7","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"51.3","Cell RNA - U-266\/84 [nTPM]":"54.4","Cell RNA - U-698 [nTPM]":"1475.5","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"2.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"6.2","Blood RNA - classical monocyte [nTPM]":"13.0","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"44.9","Blood RNA - intermediate monocyte [nTPM]":"192.2","Blood RNA - MAIT T-cell [nTPM]":"51.3","Blood RNA - memory B-cell [nTPM]":"1132.1","Blood RNA - memory CD4 T-cell [nTPM]":"57.1","Blood RNA - memory CD8 T-cell [nTPM]":"30.1","Blood RNA - myeloid DC [nTPM]":"47.0","Blood RNA - naive B-cell [nTPM]":"1505.8","Blood RNA - naive CD4 T-cell [nTPM]":"38.4","Blood RNA - naive CD8 T-cell [nTPM]":"23.2","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"42.4","Blood RNA - non-classical monocyte [nTPM]":"304.3","Blood RNA - plasmacytoid DC [nTPM]":"6.7","Blood RNA - T-reg [nTPM]":"107.9","Blood RNA - total PBMC [nTPM]":"112.1","Brain RNA - amygdala [nTPM]":"0.9","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"0.9","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"1.0","Single Cell Type RNA - Adipocytes [nTPM]":"24.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"491.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"24.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.0","Single Cell Type RNA - Endothelial cells [nTPM]":"25.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"15.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"51.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"13.4","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"14.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"99.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"27.0","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.8","Single Cell Type RNA - Urothelial cells [nTPM]":"0.2"},{"Gene":"CDC73","Gene synonym":["C1orf28","FIHP","HRPT1","HRPT2","parafibromin"],"Ensembl":"ENSG00000134371","Gene description":"Cell division cycle 73","Uniprot":["Q6P1J9"],"Chromosome":"1","Position":"193121983-193254815","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002326","CAB016359","HPA069324"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016359":"AB_628102","HPA002326":null,"HPA069324":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-3"},"Tissue RNA - adipose tissue [nTPM]":"11.3","Tissue RNA - adrenal gland [nTPM]":"9.5","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"6.9","Tissue RNA - bone marrow [nTPM]":"8.9","Tissue RNA - breast [nTPM]":"10.7","Tissue RNA - cerebellum [nTPM]":"6.1","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"11.1","Tissue RNA - choroid plexus [nTPM]":"4.5","Tissue RNA - colon [nTPM]":"10.2","Tissue RNA - duodenum [nTPM]":"5.6","Tissue RNA - endometrium 1 [nTPM]":"10.3","Tissue RNA - epididymis [nTPM]":"8.5","Tissue RNA - esophagus [nTPM]":"8.4","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"5.9","Tissue RNA - heart muscle [nTPM]":"9.6","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"8.1","Tissue RNA - kidney [nTPM]":"10.4","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"7.2","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"12.9","Tissue RNA - pituitary gland [nTPM]":"5.6","Tissue RNA - placenta [nTPM]":"9.4","Tissue RNA - pons [nTPM]":"7.9","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"9.0","Tissue RNA - retina [nTPM]":"10.1","Tissue RNA - salivary gland [nTPM]":"7.7","Tissue RNA - seminal vesicle [nTPM]":"9.7","Tissue RNA - skeletal muscle [nTPM]":"12.2","Tissue RNA - skin 1 [nTPM]":"7.0","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"10.3","Tissue RNA - spinal cord [nTPM]":"7.9","Tissue RNA - spleen [nTPM]":"8.6","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"6.5","Tissue RNA - thymus [nTPM]":"10.6","Tissue RNA - thyroid gland [nTPM]":"13.1","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"7.9","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"8.3","Cell RNA - A-431 [nTPM]":"9.3","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"16.6","Cell RNA - AN3-CA [nTPM]":"11.5","Cell RNA - ASC diff [nTPM]":"18.3","Cell RNA - ASC TERT1 [nTPM]":"18.9","Cell RNA - BEWO [nTPM]":"4.9","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"16.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.4","Cell RNA - CACO-2 [nTPM]":"6.5","Cell RNA - CAPAN-2 [nTPM]":"12.3","Cell RNA - Daudi [nTPM]":"10.5","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"20.4","Cell RNA - GAMG [nTPM]":"8.8","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"16.8","Cell RNA - HBEC3-KT [nTPM]":"14.9","Cell RNA - HBF TERT88 [nTPM]":"24.7","Cell RNA - HDLM-2 [nTPM]":"6.1","Cell RNA - HEK 293 [nTPM]":"4.1","Cell RNA - HEL [nTPM]":"7.3","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"7.2","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"16.0","Cell RNA - HMC-1 [nTPM]":"11.6","Cell RNA - HSkMC [nTPM]":"13.7","Cell RNA - hTCEpi [nTPM]":"16.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.9","Cell RNA - hTERT-HME1 [nTPM]":"17.7","Cell RNA - hTERT-RPE1 [nTPM]":"20.6","Cell RNA - HUVEC TERT2 [nTPM]":"17.8","Cell RNA - JURKAT [nTPM]":"11.1","Cell RNA - K-562 [nTPM]":"8.1","Cell RNA - Karpas-707 [nTPM]":"14.2","Cell RNA - LHCN-M2 [nTPM]":"28.8","Cell RNA - MCF7 [nTPM]":"3.5","Cell RNA - MOLT-4 [nTPM]":"13.9","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"11.9","Cell RNA - OE19 [nTPM]":"21.9","Cell RNA - PC-3 [nTPM]":"2.5","Cell RNA - REH [nTPM]":"10.6","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"15.0","Cell RNA - RPTEC TERT1 [nTPM]":"26.6","Cell RNA - RT4 [nTPM]":"8.2","Cell RNA - SCLC-21H [nTPM]":"3.9","Cell RNA - SH-SY5Y [nTPM]":"12.3","Cell RNA - SiHa [nTPM]":"8.6","Cell RNA - SK-BR-3 [nTPM]":"26.8","Cell RNA - SK-MEL-30 [nTPM]":"22.3","Cell RNA - SuSa [nTPM]":"21.0","Cell RNA - T-47d [nTPM]":"18.3","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"9.2","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"12.6","Cell RNA - U-266\/70 [nTPM]":"12.2","Cell RNA - U-266\/84 [nTPM]":"7.2","Cell RNA - U-698 [nTPM]":"7.6","Cell RNA - U-87 MG [nTPM]":"11.9","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"30.1","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"1.2","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"1.3","Blood RNA - non-classical monocyte [nTPM]":"0.8","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"6.9","Brain RNA - cerebellum [nTPM]":"6.1","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"8.1","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"7.2","Brain RNA - pons [nTPM]":"7.9","Brain RNA - spinal cord [nTPM]":"7.9","Brain RNA - thalamus [nTPM]":"6.5","Brain RNA - white matter [nTPM]":"8.3","Single Cell Type RNA - Adipocytes [nTPM]":"44.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.4","Single Cell Type RNA - Astrocytes [nTPM]":"54.5","Single Cell Type RNA - B-cells [nTPM]":"44.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"36.5","Single Cell Type RNA - Bipolar cells [nTPM]":"30.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"27.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.0","Single Cell Type RNA - dendritic cells [nTPM]":"48.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"19.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.6","Single Cell Type RNA - Endothelial cells [nTPM]":"38.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.4","Single Cell Type RNA - Erythroid cells [nTPM]":"40.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"42.0","Single Cell Type RNA - Fibroblasts [nTPM]":"39.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.8","Single Cell Type RNA - granulocytes [nTPM]":"41.1","Single Cell Type RNA - Granulosa cells [nTPM]":"17.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"31.6","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"76.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"27.4","Single Cell Type RNA - Langerhans cells [nTPM]":"49.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.5","Single Cell Type RNA - Leydig cells [nTPM]":"33.5","Single Cell Type RNA - Macrophages [nTPM]":"38.3","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"46.0","Single Cell Type RNA - Muller glia cells [nTPM]":"35.2","Single Cell Type RNA - NK-cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"112.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.5","Single Cell Type RNA - Paneth cells [nTPM]":"16.9","Single Cell Type RNA - Peritubular cells [nTPM]":"36.1","Single Cell Type RNA - Plasma cells [nTPM]":"50.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"19.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"36.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.7","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"49.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"48.3","Single Cell Type RNA - Spermatocytes [nTPM]":"55.6","Single Cell Type RNA - Spermatogonia [nTPM]":"33.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"36.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - T-cells [nTPM]":"44.4","Single Cell Type RNA - Theca cells [nTPM]":"30.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"27.9"},{"Gene":"CDH1","Gene synonym":["CD324","UVO","uvomorulin"],"Ensembl":"ENSG00000039068","Gene description":"Cadherin 1","Uniprot":["P12830"],"Chromosome":"16","Position":"68737292-68835537","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"parathyroid gland":"197.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"451.6","Glandular and luminal cells":"321.0","Pancreatic endocrine cells":"264.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"myeloid DC":"1.7","plasmacytoid DC":"4.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"4.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"683.3","CACO-2":"241.9","CAPAN-2":"328.1","HaCaT":"318.7","hTCEpi":"217.2","MCF7":"199.6","OE19":"207.2","RT4":"237.7","T-47d":"209.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000087","HPA004812","CAB028364","CAB072855","CAB072856","CAB072857"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Plasma membrane","Cell Junctions"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000087":"AB_2533003","CAB028364":"AB_2076812","CAB072855":"AB_2665698","CAB072856":"AB_2665699","CAB072857":"AB_2665700","HPA004812":"AB_1078369"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.95e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.04e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.06e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.0","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"1.5","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"2.0","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"64.2","Tissue RNA - cerebellum [nTPM]":"0.6","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"30.0","Tissue RNA - choroid plexus [nTPM]":"19.3","Tissue RNA - colon [nTPM]":"127.5","Tissue RNA - duodenum [nTPM]":"133.9","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"39.5","Tissue RNA - esophagus [nTPM]":"76.9","Tissue RNA - fallopian tube [nTPM]":"51.5","Tissue RNA - gallbladder [nTPM]":"45.7","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"1.3","Tissue RNA - kidney [nTPM]":"39.8","Tissue RNA - liver [nTPM]":"97.2","Tissue RNA - lung [nTPM]":"36.8","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"84.0","Tissue RNA - parathyroid gland [nTPM]":"197.8","Tissue RNA - pituitary gland [nTPM]":"8.0","Tissue RNA - placenta [nTPM]":"60.9","Tissue RNA - pons [nTPM]":"1.3","Tissue RNA - prostate [nTPM]":"91.7","Tissue RNA - rectum [nTPM]":"131.0","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"71.9","Tissue RNA - seminal vesicle [nTPM]":"41.7","Tissue RNA - skeletal muscle [nTPM]":"0.3","Tissue RNA - skin 1 [nTPM]":"107.7","Tissue RNA - small intestine [nTPM]":"127.9","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"104.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"20.1","Tissue RNA - thyroid gland [nTPM]":"162.7","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"29.0","Tissue RNA - urinary bladder [nTPM]":"58.2","Tissue RNA - vagina [nTPM]":"38.1","Tissue RNA - white matter [nTPM]":"2.7","Cell RNA - A-431 [nTPM]":"147.0","Cell RNA - A549 [nTPM]":"14.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"683.3","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"241.9","Cell RNA - CAPAN-2 [nTPM]":"328.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"318.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"156.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"28.6","Cell RNA - HEK 293 [nTPM]":"3.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"48.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"217.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"199.6","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"5.5","Cell RNA - OE19 [nTPM]":"207.2","Cell RNA - PC-3 [nTPM]":"0.8","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"53.9","Cell RNA - RT4 [nTPM]":"237.7","Cell RNA - SCLC-21H [nTPM]":"8.5","Cell RNA - SH-SY5Y [nTPM]":"0.8","Cell RNA - SiHa [nTPM]":"1.4","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"58.9","Cell RNA - SuSa [nTPM]":"91.8","Cell RNA - T-47d [nTPM]":"209.2","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.4","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.7","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"1.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"4.7","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.5","Brain RNA - basal ganglia [nTPM]":"2.0","Brain RNA - cerebellum [nTPM]":"0.6","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"1.3","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"1.3","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"131.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"69.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"1.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"94.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"130.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"73.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"137.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"83.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"128.7","Single Cell Type RNA - Club cells [nTPM]":"95.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"163.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"117.6","Single Cell Type RNA - dendritic cells [nTPM]":"2.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"451.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"129.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"159.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.2","Single Cell Type RNA - Endothelial cells [nTPM]":"4.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"86.7","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"113.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"29.6","Single Cell Type RNA - Fibroblasts [nTPM]":"3.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"132.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"321.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"63.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"208.3","Single Cell Type RNA - Ionocytes [nTPM]":"75.3","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"13.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"3.2","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"3.3","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"264.6","Single Cell Type RNA - Paneth cells [nTPM]":"204.6","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"195.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"159.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"118.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"100.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"131.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.5","Single Cell Type RNA - T-cells [nTPM]":"2.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.8","Single Cell Type RNA - Urothelial cells [nTPM]":"251.5"},{"Gene":"CDH11","Gene synonym":["CAD11","OB"],"Ensembl":"ENSG00000140937","Gene description":"Cadherin 11","Uniprot":["P55287"],"Chromosome":"16","Position":"64943753-65126112","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"178.2","placenta":"122.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"93.0","Endometrial stromal cells":"125.0","Excitatory neurons":"122.2","Fibroblasts":"102.2","Microglial cells":"145.2","Oligodendrocyte precursor cells":"158.3","Oligodendrocytes":"106.3","Theca cells":"160.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"246.5","BJ hTERT+":"139.3","fHDF\/TERT166":"332.3","HSkMC":"217.4","PC-3":"291.2","U-2197":"194.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013072"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4800000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB013072":"AB_2533068"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.75e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-9"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.07e-3"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"8.6","Tissue RNA - amygdala [nTPM]":"12.4","Tissue RNA - appendix [nTPM]":"25.7","Tissue RNA - basal ganglia [nTPM]":"27.9","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"10.7","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"15.8","Tissue RNA - cervix [nTPM]":"57.7","Tissue RNA - choroid plexus [nTPM]":"13.8","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"52.8","Tissue RNA - epididymis [nTPM]":"9.5","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"12.5","Tissue RNA - gallbladder [nTPM]":"58.6","Tissue RNA - heart muscle [nTPM]":"10.2","Tissue RNA - hippocampal formation [nTPM]":"19.2","Tissue RNA - hypothalamus [nTPM]":"21.4","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"45.6","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"17.1","Tissue RNA - midbrain [nTPM]":"24.1","Tissue RNA - ovary [nTPM]":"178.2","Tissue RNA - pancreas [nTPM]":"3.4","Tissue RNA - parathyroid gland [nTPM]":"2.6","Tissue RNA - pituitary gland [nTPM]":"10.4","Tissue RNA - placenta [nTPM]":"122.2","Tissue RNA - pons [nTPM]":"17.3","Tissue RNA - prostate [nTPM]":"20.0","Tissue RNA - rectum [nTPM]":"12.2","Tissue RNA - retina [nTPM]":"14.0","Tissue RNA - salivary gland [nTPM]":"12.7","Tissue RNA - seminal vesicle [nTPM]":"24.3","Tissue RNA - skeletal muscle [nTPM]":"2.6","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"54.3","Tissue RNA - spinal cord [nTPM]":"21.1","Tissue RNA - spleen [nTPM]":"89.3","Tissue RNA - stomach 1 [nTPM]":"11.8","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"13.0","Tissue RNA - urinary bladder [nTPM]":"47.6","Tissue RNA - vagina [nTPM]":"13.6","Tissue RNA - white matter [nTPM]":"21.4","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"51.4","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"35.7","Cell RNA - ASC TERT1 [nTPM]":"77.5","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"246.5","Cell RNA - BJ hTERT+ [nTPM]":"139.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"61.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"34.5","Cell RNA - CACO-2 [nTPM]":"4.6","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"332.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"1.7","Cell RNA - HBF TERT88 [nTPM]":"43.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"29.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"14.4","Cell RNA - HSkMC [nTPM]":"217.4","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"74.7","Cell RNA - hTERT-HME1 [nTPM]":"14.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"17.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"33.1","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"19.2","Cell RNA - OE19 [nTPM]":"37.4","Cell RNA - PC-3 [nTPM]":"291.2","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"38.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"36.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"64.5","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"124.4","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"194.0","Cell RNA - U-251 MG [nTPM]":"70.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"21.5","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"12.4","Brain RNA - basal ganglia [nTPM]":"27.9","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"15.8","Brain RNA - hippocampal formation [nTPM]":"19.2","Brain RNA - hypothalamus [nTPM]":"21.4","Brain RNA - medulla oblongata [nTPM]":"17.1","Brain RNA - midbrain [nTPM]":"24.1","Brain RNA - pons [nTPM]":"17.3","Brain RNA - spinal cord [nTPM]":"21.1","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"21.4","Single Cell Type RNA - Adipocytes [nTPM]":"11.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"93.0","Single Cell Type RNA - B-cells [nTPM]":"0.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"19.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"3.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"125.0","Single Cell Type RNA - Endothelial cells [nTPM]":"17.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"122.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"102.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.7","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"60.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"67.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"6.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.2","Single Cell Type RNA - Leydig cells [nTPM]":"52.5","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"145.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"41.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"158.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"106.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"77.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.7","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"1.1","Single Cell Type RNA - Theca cells [nTPM]":"160.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"CDK4","Gene synonym":["PSK-J3"],"Ensembl":"ENSG00000135446","Gene description":"Cyclin dependent kinase 4","Uniprot":["P11802"],"Chromosome":"12","Position":"57747727-57756013","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"175.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in all","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"HBEC3-KT":"2594.8","LHCN-M2":"2819.4","RH-30":"8902.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006024","CAB013116","CAB069405"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Nuclear membrane","Nucleoli"],"Antibody RRID":{"CAB013116":"AB_2536376","CAB069405":"AB_1613464","HPA006024":"AB_2667497"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.09e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.10e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.15e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Tissue RNA - adipose tissue [nTPM]":"69.7","Tissue RNA - adrenal gland [nTPM]":"87.8","Tissue RNA - amygdala [nTPM]":"35.0","Tissue RNA - appendix [nTPM]":"52.8","Tissue RNA - basal ganglia [nTPM]":"37.9","Tissue RNA - bone marrow [nTPM]":"72.0","Tissue RNA - breast [nTPM]":"76.6","Tissue RNA - cerebellum [nTPM]":"37.7","Tissue RNA - cerebral cortex [nTPM]":"36.9","Tissue RNA - cervix [nTPM]":"84.3","Tissue RNA - choroid plexus [nTPM]":"35.9","Tissue RNA - colon [nTPM]":"62.6","Tissue RNA - duodenum [nTPM]":"40.2","Tissue RNA - endometrium 1 [nTPM]":"97.4","Tissue RNA - epididymis [nTPM]":"64.2","Tissue RNA - esophagus [nTPM]":"57.2","Tissue RNA - fallopian tube [nTPM]":"69.4","Tissue RNA - gallbladder [nTPM]":"57.1","Tissue RNA - heart muscle [nTPM]":"58.9","Tissue RNA - hippocampal formation [nTPM]":"33.6","Tissue RNA - hypothalamus [nTPM]":"37.1","Tissue RNA - kidney [nTPM]":"58.5","Tissue RNA - liver [nTPM]":"51.5","Tissue RNA - lung [nTPM]":"58.0","Tissue RNA - lymph node [nTPM]":"66.8","Tissue RNA - medulla oblongata [nTPM]":"37.1","Tissue RNA - midbrain [nTPM]":"36.9","Tissue RNA - ovary [nTPM]":"97.3","Tissue RNA - pancreas [nTPM]":"70.9","Tissue RNA - parathyroid gland [nTPM]":"63.5","Tissue RNA - pituitary gland [nTPM]":"67.7","Tissue RNA - placenta [nTPM]":"52.4","Tissue RNA - pons [nTPM]":"36.8","Tissue RNA - prostate [nTPM]":"52.7","Tissue RNA - rectum [nTPM]":"63.3","Tissue RNA - retina [nTPM]":"14.5","Tissue RNA - salivary gland [nTPM]":"54.4","Tissue RNA - seminal vesicle [nTPM]":"54.1","Tissue RNA - skeletal muscle [nTPM]":"48.2","Tissue RNA - skin 1 [nTPM]":"58.9","Tissue RNA - small intestine [nTPM]":"47.2","Tissue RNA - smooth muscle [nTPM]":"80.4","Tissue RNA - spinal cord [nTPM]":"37.3","Tissue RNA - spleen [nTPM]":"51.5","Tissue RNA - stomach 1 [nTPM]":"54.8","Tissue RNA - testis [nTPM]":"24.1","Tissue RNA - thalamus [nTPM]":"37.3","Tissue RNA - thymus [nTPM]":"67.6","Tissue RNA - thyroid gland [nTPM]":"66.0","Tissue RNA - tongue [nTPM]":"52.7","Tissue RNA - tonsil [nTPM]":"70.6","Tissue RNA - urinary bladder [nTPM]":"71.6","Tissue RNA - vagina [nTPM]":"60.7","Tissue RNA - white matter [nTPM]":"37.6","Cell RNA - A-431 [nTPM]":"207.1","Cell RNA - A549 [nTPM]":"235.7","Cell RNA - AF22 [nTPM]":"295.7","Cell RNA - AN3-CA [nTPM]":"268.0","Cell RNA - ASC diff [nTPM]":"253.7","Cell RNA - ASC TERT1 [nTPM]":"220.7","Cell RNA - BEWO [nTPM]":"210.4","Cell RNA - BJ [nTPM]":"116.1","Cell RNA - BJ hTERT+ [nTPM]":"347.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"468.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"385.7","Cell RNA - CACO-2 [nTPM]":"338.2","Cell RNA - CAPAN-2 [nTPM]":"189.1","Cell RNA - Daudi [nTPM]":"297.4","Cell RNA - EFO-21 [nTPM]":"200.2","Cell RNA - fHDF\/TERT166 [nTPM]":"173.6","Cell RNA - GAMG [nTPM]":"293.2","Cell RNA - HaCaT [nTPM]":"158.0","Cell RNA - HAP1 [nTPM]":"396.3","Cell RNA - HBEC3-KT [nTPM]":"2594.8","Cell RNA - HBF TERT88 [nTPM]":"354.9","Cell RNA - HDLM-2 [nTPM]":"150.9","Cell RNA - HEK 293 [nTPM]":"209.0","Cell RNA - HEL [nTPM]":"275.4","Cell RNA - HeLa [nTPM]":"149.5","Cell RNA - Hep G2 [nTPM]":"237.9","Cell RNA - HHSteC [nTPM]":"297.0","Cell RNA - HL-60 [nTPM]":"309.7","Cell RNA - HMC-1 [nTPM]":"182.5","Cell RNA - HSkMC [nTPM]":"221.5","Cell RNA - hTCEpi [nTPM]":"180.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"294.2","Cell RNA - hTERT-HME1 [nTPM]":"326.7","Cell RNA - hTERT-RPE1 [nTPM]":"326.4","Cell RNA - HUVEC TERT2 [nTPM]":"304.8","Cell RNA - JURKAT [nTPM]":"280.0","Cell RNA - K-562 [nTPM]":"301.3","Cell RNA - Karpas-707 [nTPM]":"242.7","Cell RNA - LHCN-M2 [nTPM]":"2819.4","Cell RNA - MCF7 [nTPM]":"304.9","Cell RNA - MOLT-4 [nTPM]":"296.7","Cell RNA - NB-4 [nTPM]":"256.5","Cell RNA - NTERA-2 [nTPM]":"347.0","Cell RNA - OE19 [nTPM]":"208.0","Cell RNA - PC-3 [nTPM]":"249.8","Cell RNA - REH [nTPM]":"267.3","Cell RNA - RH-30 [nTPM]":"8902.5","Cell RNA - RPMI-8226 [nTPM]":"272.1","Cell RNA - RPTEC TERT1 [nTPM]":"147.2","Cell RNA - RT4 [nTPM]":"320.6","Cell RNA - SCLC-21H [nTPM]":"271.2","Cell RNA - SH-SY5Y [nTPM]":"251.7","Cell RNA - SiHa [nTPM]":"205.3","Cell RNA - SK-BR-3 [nTPM]":"150.2","Cell RNA - SK-MEL-30 [nTPM]":"310.0","Cell RNA - SuSa [nTPM]":"195.1","Cell RNA - T-47d [nTPM]":"202.8","Cell RNA - THP-1 [nTPM]":"380.7","Cell RNA - TIME [nTPM]":"146.1","Cell RNA - U-138 MG [nTPM]":"233.6","Cell RNA - U-2 OS [nTPM]":"217.0","Cell RNA - U-2197 [nTPM]":"265.8","Cell RNA - U-251 MG [nTPM]":"233.1","Cell RNA - U-266\/70 [nTPM]":"122.2","Cell RNA - U-266\/84 [nTPM]":"206.1","Cell RNA - U-698 [nTPM]":"450.8","Cell RNA - U-87 MG [nTPM]":"214.1","Cell RNA - U-937 [nTPM]":"291.3","Cell RNA - WM-115 [nTPM]":"286.9","Blood RNA - basophil [nTPM]":"9.5","Blood RNA - classical monocyte [nTPM]":"46.5","Blood RNA - eosinophil [nTPM]":"10.3","Blood RNA - gdT-cell [nTPM]":"79.6","Blood RNA - intermediate monocyte [nTPM]":"65.6","Blood RNA - MAIT T-cell [nTPM]":"81.8","Blood RNA - memory B-cell [nTPM]":"93.5","Blood RNA - memory CD4 T-cell [nTPM]":"70.0","Blood RNA - memory CD8 T-cell [nTPM]":"72.5","Blood RNA - myeloid DC [nTPM]":"66.7","Blood RNA - naive B-cell [nTPM]":"90.0","Blood RNA - naive CD4 T-cell [nTPM]":"93.0","Blood RNA - naive CD8 T-cell [nTPM]":"84.4","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"56.6","Blood RNA - non-classical monocyte [nTPM]":"41.9","Blood RNA - plasmacytoid DC [nTPM]":"84.9","Blood RNA - T-reg [nTPM]":"57.0","Blood RNA - total PBMC [nTPM]":"73.6","Brain RNA - amygdala [nTPM]":"35.0","Brain RNA - basal ganglia [nTPM]":"37.9","Brain RNA - cerebellum [nTPM]":"37.7","Brain RNA - cerebral cortex [nTPM]":"36.9","Brain RNA - hippocampal formation [nTPM]":"33.6","Brain RNA - hypothalamus [nTPM]":"37.1","Brain RNA - medulla oblongata [nTPM]":"37.1","Brain RNA - midbrain [nTPM]":"36.9","Brain RNA - pons [nTPM]":"36.8","Brain RNA - spinal cord [nTPM]":"37.3","Brain RNA - thalamus [nTPM]":"37.3","Brain RNA - white matter [nTPM]":"37.6","Single Cell Type RNA - Adipocytes [nTPM]":"47.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.8","Single Cell Type RNA - Astrocytes [nTPM]":"7.8","Single Cell Type RNA - B-cells [nTPM]":"40.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"78.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"83.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"74.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"67.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"82.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"35.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"82.9","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"15.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Ductal cells [nTPM]":"93.1","Single Cell Type RNA - Early spermatids [nTPM]":"13.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"77.7","Single Cell Type RNA - Endothelial cells [nTPM]":"50.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.6","Single Cell Type RNA - Erythroid cells [nTPM]":"98.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"62.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"134.5","Single Cell Type RNA - Fibroblasts [nTPM]":"79.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"22.6","Single Cell Type RNA - granulocytes [nTPM]":"69.1","Single Cell Type RNA - Granulosa cells [nTPM]":"60.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.7","Single Cell Type RNA - Hepatocytes [nTPM]":"35.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"132.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"42.2","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"25.1","Single Cell Type RNA - Langerhans cells [nTPM]":"44.1","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"64.0","Single Cell Type RNA - Macrophages [nTPM]":"31.2","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"41.9","Single Cell Type RNA - Muller glia cells [nTPM]":"51.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.3","Single Cell Type RNA - Paneth cells [nTPM]":"18.9","Single Cell Type RNA - Peritubular cells [nTPM]":"63.2","Single Cell Type RNA - Plasma cells [nTPM]":"57.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"113.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"80.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"61.9","Single Cell Type RNA - Spermatocytes [nTPM]":"32.1","Single Cell Type RNA - Spermatogonia [nTPM]":"48.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"74.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"86.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"46.8","Single Cell Type RNA - T-cells [nTPM]":"32.3","Single Cell Type RNA - Theca cells [nTPM]":"78.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"78.7","Single Cell Type RNA - Urothelial cells [nTPM]":"49.4"},{"Gene":"CDKN1A","Gene synonym":["CAP20","CDKN1","CIP1","P21","p21CIP1","p21Cip1\/Waf1","SDI1","WAF1"],"Ensembl":"ENSG00000124762","Gene description":"Cyclin dependent kinase inhibitor 1A","Uniprot":["P38936"],"Chromosome":"6","Position":"36676460-36687337","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Protein kinase inhibitor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"74.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"B-cells":"20.7","dendritic cells":"21.5","monocytes":"74.5"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"798.5","HSkMC":"586.5","hTCEpi":"775.8","LHCN-M2":"604.2"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"olfactory bulb":"76.0"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000064","HPA005946","CAB069401"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB000064":null,"CAB069401":"AB_1620493","HPA005946":"AB_2667477"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.14e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.05e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.55e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.95e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-2"},"Tissue RNA - adipose tissue [nTPM]":"322.1","Tissue RNA - adrenal gland [nTPM]":"98.1","Tissue RNA - amygdala [nTPM]":"47.0","Tissue RNA - appendix [nTPM]":"62.1","Tissue RNA - basal ganglia [nTPM]":"48.1","Tissue RNA - bone marrow [nTPM]":"72.7","Tissue RNA - breast [nTPM]":"144.2","Tissue RNA - cerebellum [nTPM]":"47.3","Tissue RNA - cerebral cortex [nTPM]":"60.9","Tissue RNA - cervix [nTPM]":"123.3","Tissue RNA - choroid plexus [nTPM]":"85.9","Tissue RNA - colon [nTPM]":"119.0","Tissue RNA - duodenum [nTPM]":"115.2","Tissue RNA - endometrium 1 [nTPM]":"74.4","Tissue RNA - epididymis [nTPM]":"41.0","Tissue RNA - esophagus [nTPM]":"203.2","Tissue RNA - fallopian tube [nTPM]":"213.9","Tissue RNA - gallbladder [nTPM]":"132.6","Tissue RNA - heart muscle [nTPM]":"170.6","Tissue RNA - hippocampal formation [nTPM]":"47.2","Tissue RNA - hypothalamus [nTPM]":"49.5","Tissue RNA - kidney [nTPM]":"149.9","Tissue RNA - liver [nTPM]":"173.4","Tissue RNA - lung [nTPM]":"182.2","Tissue RNA - lymph node [nTPM]":"17.3","Tissue RNA - medulla oblongata [nTPM]":"63.7","Tissue RNA - midbrain [nTPM]":"54.6","Tissue RNA - ovary [nTPM]":"184.9","Tissue RNA - pancreas [nTPM]":"130.5","Tissue RNA - parathyroid gland [nTPM]":"70.1","Tissue RNA - pituitary gland [nTPM]":"104.4","Tissue RNA - placenta [nTPM]":"44.7","Tissue RNA - pons [nTPM]":"53.4","Tissue RNA - prostate [nTPM]":"91.4","Tissue RNA - rectum [nTPM]":"108.2","Tissue RNA - retina [nTPM]":"29.2","Tissue RNA - salivary gland [nTPM]":"79.1","Tissue RNA - seminal vesicle [nTPM]":"29.4","Tissue RNA - skeletal muscle [nTPM]":"241.6","Tissue RNA - skin 1 [nTPM]":"224.4","Tissue RNA - small intestine [nTPM]":"130.0","Tissue RNA - smooth muscle [nTPM]":"114.3","Tissue RNA - spinal cord [nTPM]":"55.0","Tissue RNA - spleen [nTPM]":"34.4","Tissue RNA - stomach 1 [nTPM]":"121.3","Tissue RNA - testis [nTPM]":"47.0","Tissue RNA - thalamus [nTPM]":"50.3","Tissue RNA - thymus [nTPM]":"59.7","Tissue RNA - thyroid gland [nTPM]":"77.5","Tissue RNA - tongue [nTPM]":"26.9","Tissue RNA - tonsil [nTPM]":"21.8","Tissue RNA - urinary bladder [nTPM]":"212.7","Tissue RNA - vagina [nTPM]":"142.3","Tissue RNA - white matter [nTPM]":"53.6","Cell RNA - A-431 [nTPM]":"27.0","Cell RNA - A549 [nTPM]":"108.1","Cell RNA - AF22 [nTPM]":"80.1","Cell RNA - AN3-CA [nTPM]":"2.0","Cell RNA - ASC diff [nTPM]":"273.3","Cell RNA - ASC TERT1 [nTPM]":"490.3","Cell RNA - BEWO [nTPM]":"149.5","Cell RNA - BJ [nTPM]":"435.6","Cell RNA - BJ hTERT+ [nTPM]":"344.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"203.7","Cell RNA - CACO-2 [nTPM]":"9.6","Cell RNA - CAPAN-2 [nTPM]":"25.3","Cell RNA - Daudi [nTPM]":"18.3","Cell RNA - EFO-21 [nTPM]":"15.5","Cell RNA - fHDF\/TERT166 [nTPM]":"267.9","Cell RNA - GAMG [nTPM]":"48.0","Cell RNA - HaCaT [nTPM]":"60.2","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"477.7","Cell RNA - HBF TERT88 [nTPM]":"82.4","Cell RNA - HDLM-2 [nTPM]":"36.2","Cell RNA - HEK 293 [nTPM]":"22.0","Cell RNA - HEL [nTPM]":"3.0","Cell RNA - HeLa [nTPM]":"85.8","Cell RNA - Hep G2 [nTPM]":"137.0","Cell RNA - HHSteC [nTPM]":"798.5","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"127.7","Cell RNA - HSkMC [nTPM]":"586.5","Cell RNA - hTCEpi [nTPM]":"775.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"476.2","Cell RNA - hTERT-HME1 [nTPM]":"147.1","Cell RNA - hTERT-RPE1 [nTPM]":"309.3","Cell RNA - HUVEC TERT2 [nTPM]":"275.3","Cell RNA - JURKAT [nTPM]":"1.4","Cell RNA - K-562 [nTPM]":"5.1","Cell RNA - Karpas-707 [nTPM]":"120.8","Cell RNA - LHCN-M2 [nTPM]":"604.2","Cell RNA - MCF7 [nTPM]":"57.4","Cell RNA - MOLT-4 [nTPM]":"3.9","Cell RNA - NB-4 [nTPM]":"11.3","Cell RNA - NTERA-2 [nTPM]":"10.2","Cell RNA - OE19 [nTPM]":"112.8","Cell RNA - PC-3 [nTPM]":"15.5","Cell RNA - REH [nTPM]":"54.4","Cell RNA - RH-30 [nTPM]":"67.1","Cell RNA - RPMI-8226 [nTPM]":"31.9","Cell RNA - RPTEC TERT1 [nTPM]":"91.2","Cell RNA - RT4 [nTPM]":"201.5","Cell RNA - SCLC-21H [nTPM]":"36.7","Cell RNA - SH-SY5Y [nTPM]":"35.6","Cell RNA - SiHa [nTPM]":"101.3","Cell RNA - SK-BR-3 [nTPM]":"8.4","Cell RNA - SK-MEL-30 [nTPM]":"21.3","Cell RNA - SuSa [nTPM]":"185.2","Cell RNA - T-47d [nTPM]":"32.7","Cell RNA - THP-1 [nTPM]":"111.2","Cell RNA - TIME [nTPM]":"155.8","Cell RNA - U-138 MG [nTPM]":"91.5","Cell RNA - U-2 OS [nTPM]":"86.9","Cell RNA - U-2197 [nTPM]":"6.2","Cell RNA - U-251 MG [nTPM]":"36.4","Cell RNA - U-266\/70 [nTPM]":"202.0","Cell RNA - U-266\/84 [nTPM]":"42.9","Cell RNA - U-698 [nTPM]":"54.5","Cell RNA - U-87 MG [nTPM]":"118.7","Cell RNA - U-937 [nTPM]":"9.9","Cell RNA - WM-115 [nTPM]":"261.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"22.8","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.5","Blood RNA - intermediate monocyte [nTPM]":"52.2","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"20.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"20.0","Blood RNA - naive B-cell [nTPM]":"16.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"4.2","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"74.5","Blood RNA - plasmacytoid DC [nTPM]":"21.5","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"34.2","Brain RNA - amygdala [nTPM]":"47.0","Brain RNA - basal ganglia [nTPM]":"48.1","Brain RNA - cerebellum [nTPM]":"47.3","Brain RNA - cerebral cortex [nTPM]":"60.9","Brain RNA - hippocampal formation [nTPM]":"47.2","Brain RNA - hypothalamus [nTPM]":"49.5","Brain RNA - medulla oblongata [nTPM]":"63.7","Brain RNA - midbrain [nTPM]":"54.6","Brain RNA - pons [nTPM]":"53.4","Brain RNA - spinal cord [nTPM]":"55.0","Brain RNA - thalamus [nTPM]":"50.3","Brain RNA - white matter [nTPM]":"53.6","Single Cell Type RNA - Adipocytes [nTPM]":"571.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"83.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"126.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"440.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"340.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"293.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"512.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"203.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"187.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"151.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"214.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"68.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.1","Single Cell Type RNA - dendritic cells [nTPM]":"56.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"505.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"217.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"227.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.3","Single Cell Type RNA - Endothelial cells [nTPM]":"327.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"175.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"264.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"52.8","Single Cell Type RNA - Fibroblasts [nTPM]":"302.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"150.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"199.2","Single Cell Type RNA - granulocytes [nTPM]":"104.4","Single Cell Type RNA - Granulosa cells [nTPM]":"20.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"71.7","Single Cell Type RNA - Hepatocytes [nTPM]":"68.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"197.1","Single Cell Type RNA - Ionocytes [nTPM]":"156.6","Single Cell Type RNA - Kupffer cells [nTPM]":"62.0","Single Cell Type RNA - Langerhans cells [nTPM]":"556.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"34.5","Single Cell Type RNA - Macrophages [nTPM]":"277.6","Single Cell Type RNA - Melanocytes [nTPM]":"218.7","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"280.6","Single Cell Type RNA - Muller glia cells [nTPM]":"58.4","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"429.9","Single Cell Type RNA - Paneth cells [nTPM]":"466.1","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"376.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"201.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"383.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"215.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"303.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"471.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"620.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"672.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"155.3","Single Cell Type RNA - T-cells [nTPM]":"106.0","Single Cell Type RNA - Theca cells [nTPM]":"10.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"75.8","Single Cell Type RNA - Urothelial cells [nTPM]":"478.0"},{"Gene":"CDKN1B","Gene synonym":["KIP1","P27KIP1"],"Ensembl":"ENSG00000111276","Gene description":"Cyclin dependent kinase inhibitor 1B","Uniprot":["P46527"],"Chromosome":"12","Position":"12715058-12722369","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Protein kinase inhibitor"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Muller glia cells":"182.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003691","CAB021888","HPA059086"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB003691":"AB_425362","CAB021888":null,"HPA059086":"AB_2683900"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.15e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.84e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.25e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.39e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Tissue RNA - adipose tissue [nTPM]":"53.4","Tissue RNA - adrenal gland [nTPM]":"44.7","Tissue RNA - amygdala [nTPM]":"53.6","Tissue RNA - appendix [nTPM]":"40.1","Tissue RNA - basal ganglia [nTPM]":"70.6","Tissue RNA - bone marrow [nTPM]":"68.1","Tissue RNA - breast [nTPM]":"50.2","Tissue RNA - cerebellum [nTPM]":"73.4","Tissue RNA - cerebral cortex [nTPM]":"81.3","Tissue RNA - cervix [nTPM]":"55.3","Tissue RNA - choroid plexus [nTPM]":"43.1","Tissue RNA - colon [nTPM]":"43.9","Tissue RNA - duodenum [nTPM]":"44.5","Tissue RNA - endometrium 1 [nTPM]":"41.0","Tissue RNA - epididymis [nTPM]":"24.5","Tissue RNA - esophagus [nTPM]":"29.1","Tissue RNA - fallopian tube [nTPM]":"47.3","Tissue RNA - gallbladder [nTPM]":"24.6","Tissue RNA - heart muscle [nTPM]":"32.9","Tissue RNA - hippocampal formation [nTPM]":"47.9","Tissue RNA - hypothalamus [nTPM]":"58.9","Tissue RNA - kidney [nTPM]":"30.2","Tissue RNA - liver [nTPM]":"35.2","Tissue RNA - lung [nTPM]":"38.9","Tissue RNA - lymph node [nTPM]":"55.3","Tissue RNA - medulla oblongata [nTPM]":"58.6","Tissue RNA - midbrain [nTPM]":"58.3","Tissue RNA - ovary [nTPM]":"66.1","Tissue RNA - pancreas [nTPM]":"23.9","Tissue RNA - parathyroid gland [nTPM]":"34.4","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"41.0","Tissue RNA - pons [nTPM]":"61.2","Tissue RNA - prostate [nTPM]":"35.9","Tissue RNA - rectum [nTPM]":"32.5","Tissue RNA - retina [nTPM]":"55.3","Tissue RNA - salivary gland [nTPM]":"36.3","Tissue RNA - seminal vesicle [nTPM]":"33.4","Tissue RNA - skeletal muscle [nTPM]":"81.4","Tissue RNA - skin 1 [nTPM]":"45.4","Tissue RNA - small intestine [nTPM]":"40.7","Tissue RNA - smooth muscle [nTPM]":"24.8","Tissue RNA - spinal cord [nTPM]":"55.1","Tissue RNA - spleen [nTPM]":"55.1","Tissue RNA - stomach 1 [nTPM]":"30.0","Tissue RNA - testis [nTPM]":"25.8","Tissue RNA - thalamus [nTPM]":"58.3","Tissue RNA - thymus [nTPM]":"71.8","Tissue RNA - thyroid gland [nTPM]":"33.7","Tissue RNA - tongue [nTPM]":"63.4","Tissue RNA - tonsil [nTPM]":"39.9","Tissue RNA - urinary bladder [nTPM]":"32.0","Tissue RNA - vagina [nTPM]":"44.5","Tissue RNA - white matter [nTPM]":"91.2","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"16.6","Cell RNA - AF22 [nTPM]":"94.5","Cell RNA - AN3-CA [nTPM]":"16.6","Cell RNA - ASC diff [nTPM]":"32.0","Cell RNA - ASC TERT1 [nTPM]":"18.0","Cell RNA - BEWO [nTPM]":"46.1","Cell RNA - BJ [nTPM]":"31.5","Cell RNA - BJ hTERT+ [nTPM]":"53.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.4","Cell RNA - CACO-2 [nTPM]":"47.7","Cell RNA - CAPAN-2 [nTPM]":"40.4","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"12.5","Cell RNA - fHDF\/TERT166 [nTPM]":"19.6","Cell RNA - GAMG [nTPM]":"16.6","Cell RNA - HaCaT [nTPM]":"34.2","Cell RNA - HAP1 [nTPM]":"44.9","Cell RNA - HBEC3-KT [nTPM]":"16.7","Cell RNA - HBF TERT88 [nTPM]":"41.1","Cell RNA - HDLM-2 [nTPM]":"62.4","Cell RNA - HEK 293 [nTPM]":"31.5","Cell RNA - HEL [nTPM]":"28.8","Cell RNA - HeLa [nTPM]":"46.5","Cell RNA - Hep G2 [nTPM]":"53.2","Cell RNA - HHSteC [nTPM]":"42.5","Cell RNA - HL-60 [nTPM]":"24.5","Cell RNA - HMC-1 [nTPM]":"18.6","Cell RNA - HSkMC [nTPM]":"19.8","Cell RNA - hTCEpi [nTPM]":"35.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.2","Cell RNA - hTERT-HME1 [nTPM]":"44.0","Cell RNA - hTERT-RPE1 [nTPM]":"107.8","Cell RNA - HUVEC TERT2 [nTPM]":"27.8","Cell RNA - JURKAT [nTPM]":"54.5","Cell RNA - K-562 [nTPM]":"31.5","Cell RNA - Karpas-707 [nTPM]":"101.6","Cell RNA - LHCN-M2 [nTPM]":"16.6","Cell RNA - MCF7 [nTPM]":"45.9","Cell RNA - MOLT-4 [nTPM]":"32.7","Cell RNA - NB-4 [nTPM]":"35.3","Cell RNA - NTERA-2 [nTPM]":"38.0","Cell RNA - OE19 [nTPM]":"32.1","Cell RNA - PC-3 [nTPM]":"16.8","Cell RNA - REH [nTPM]":"25.2","Cell RNA - RH-30 [nTPM]":"30.9","Cell RNA - RPMI-8226 [nTPM]":"63.1","Cell RNA - RPTEC TERT1 [nTPM]":"22.5","Cell RNA - RT4 [nTPM]":"38.6","Cell RNA - SCLC-21H [nTPM]":"35.6","Cell RNA - SH-SY5Y [nTPM]":"58.4","Cell RNA - SiHa [nTPM]":"48.9","Cell RNA - SK-BR-3 [nTPM]":"34.8","Cell RNA - SK-MEL-30 [nTPM]":"65.8","Cell RNA - SuSa [nTPM]":"33.7","Cell RNA - T-47d [nTPM]":"18.6","Cell RNA - THP-1 [nTPM]":"54.6","Cell RNA - TIME [nTPM]":"19.1","Cell RNA - U-138 MG [nTPM]":"22.6","Cell RNA - U-2 OS [nTPM]":"34.9","Cell RNA - U-2197 [nTPM]":"20.7","Cell RNA - U-251 MG [nTPM]":"33.3","Cell RNA - U-266\/70 [nTPM]":"86.1","Cell RNA - U-266\/84 [nTPM]":"59.4","Cell RNA - U-698 [nTPM]":"33.2","Cell RNA - U-87 MG [nTPM]":"28.2","Cell RNA - U-937 [nTPM]":"36.6","Cell RNA - WM-115 [nTPM]":"22.5","Blood RNA - basophil [nTPM]":"6.2","Blood RNA - classical monocyte [nTPM]":"3.8","Blood RNA - eosinophil [nTPM]":"8.6","Blood RNA - gdT-cell [nTPM]":"5.9","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"6.1","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"7.2","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"5.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.0","Blood RNA - naive CD8 T-cell [nTPM]":"6.1","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"7.3","Blood RNA - non-classical monocyte [nTPM]":"5.5","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"12.3","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"53.6","Brain RNA - basal ganglia [nTPM]":"70.6","Brain RNA - cerebellum [nTPM]":"73.4","Brain RNA - cerebral cortex [nTPM]":"81.3","Brain RNA - hippocampal formation [nTPM]":"47.9","Brain RNA - hypothalamus [nTPM]":"58.9","Brain RNA - medulla oblongata [nTPM]":"58.6","Brain RNA - midbrain [nTPM]":"58.3","Brain RNA - pons [nTPM]":"61.2","Brain RNA - spinal cord [nTPM]":"55.1","Brain RNA - thalamus [nTPM]":"58.3","Brain RNA - white matter [nTPM]":"91.2","Single Cell Type RNA - Adipocytes [nTPM]":"64.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.3","Single Cell Type RNA - Astrocytes [nTPM]":"6.2","Single Cell Type RNA - B-cells [nTPM]":"126.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"115.5","Single Cell Type RNA - Bipolar cells [nTPM]":"45.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"39.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"27.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.9","Single Cell Type RNA - dendritic cells [nTPM]":"92.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"32.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"10.8","Single Cell Type RNA - Early spermatids [nTPM]":"70.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"35.8","Single Cell Type RNA - Endothelial cells [nTPM]":"51.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.7","Single Cell Type RNA - Erythroid cells [nTPM]":"70.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.6","Single Cell Type RNA - Fibroblasts [nTPM]":"39.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.3","Single Cell Type RNA - granulocytes [nTPM]":"31.0","Single Cell Type RNA - Granulosa cells [nTPM]":"21.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.2","Single Cell Type RNA - Hepatocytes [nTPM]":"30.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.8","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"13.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"41.4","Single Cell Type RNA - Ionocytes [nTPM]":"24.4","Single Cell Type RNA - Kupffer cells [nTPM]":"55.3","Single Cell Type RNA - Langerhans cells [nTPM]":"66.0","Single Cell Type RNA - Late spermatids [nTPM]":"67.7","Single Cell Type RNA - Leydig cells [nTPM]":"55.9","Single Cell Type RNA - Macrophages [nTPM]":"65.1","Single Cell Type RNA - Melanocytes [nTPM]":"74.7","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"31.6","Single Cell Type RNA - Muller glia cells [nTPM]":"182.9","Single Cell Type RNA - NK-cells [nTPM]":"60.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.3","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"121.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"33.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.4","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.5","Single Cell Type RNA - Spermatocytes [nTPM]":"7.7","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"102.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"52.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"39.0","Single Cell Type RNA - T-cells [nTPM]":"166.1","Single Cell Type RNA - Theca cells [nTPM]":"20.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"41.9","Single Cell Type RNA - Urothelial cells [nTPM]":"22.7"},{"Gene":"CDKN1C","Gene synonym":["BWCR","BWS","KIP2","P57"],"Ensembl":"ENSG00000129757","Gene description":"Cyclin dependent kinase inhibitor 1C","Uniprot":["P49918"],"Chromosome":"11","Position":"2883213-2885775","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Protein kinase inhibitor"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"206.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"575.3","Extravillous trophoblasts":"1531.7","Syncytiotrophoblasts":"2241.2","Theca cells":"781.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"intermediate monocyte":"155.1","non-classical monocyte":"376.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"14","RNA blood lineage specific nTPM":{"monocytes":"376.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"12.0","HeLa":"12.8","RPMI-8226":"18.7","SH-SY5Y":"33.0","SiHa":"25.2","SK-MEL-30":"15.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002924"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA002924":"AB_1079548"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.79e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.84e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.53e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Tissue RNA - adipose tissue [nTPM]":"127.4","Tissue RNA - adrenal gland [nTPM]":"182.9","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"3.3","Tissue RNA - basal ganglia [nTPM]":"38.0","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"92.5","Tissue RNA - cerebellum [nTPM]":"43.3","Tissue RNA - cerebral cortex [nTPM]":"18.7","Tissue RNA - cervix [nTPM]":"73.7","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"48.1","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"70.6","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"29.9","Tissue RNA - fallopian tube [nTPM]":"70.7","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"82.6","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"18.8","Tissue RNA - kidney [nTPM]":"149.5","Tissue RNA - liver [nTPM]":"8.3","Tissue RNA - lung [nTPM]":"34.5","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"55.1","Tissue RNA - midbrain [nTPM]":"33.5","Tissue RNA - ovary [nTPM]":"206.4","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"27.8","Tissue RNA - placenta [nTPM]":"28.1","Tissue RNA - pons [nTPM]":"45.0","Tissue RNA - prostate [nTPM]":"33.1","Tissue RNA - rectum [nTPM]":"0.2","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"21.7","Tissue RNA - seminal vesicle [nTPM]":"1.5","Tissue RNA - skeletal muscle [nTPM]":"60.3","Tissue RNA - skin 1 [nTPM]":"26.6","Tissue RNA - small intestine [nTPM]":"25.0","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"31.8","Tissue RNA - spleen [nTPM]":"20.6","Tissue RNA - stomach 1 [nTPM]":"54.1","Tissue RNA - testis [nTPM]":"8.6","Tissue RNA - thalamus [nTPM]":"34.3","Tissue RNA - thymus [nTPM]":"0.2","Tissue RNA - thyroid gland [nTPM]":"17.0","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"75.0","Tissue RNA - vagina [nTPM]":"49.4","Tissue RNA - white matter [nTPM]":"95.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"1.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.5","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.3","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"12.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"5.6","Cell RNA - HEK 293 [nTPM]":"1.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"12.8","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.4","Cell RNA - HSkMC [nTPM]":"2.4","Cell RNA - hTCEpi [nTPM]":"1.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"2.7","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"0.5","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"6.0","Cell RNA - NTERA-2 [nTPM]":"10.6","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"4.0","Cell RNA - REH [nTPM]":"2.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"18.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"3.5","Cell RNA - SH-SY5Y [nTPM]":"33.0","Cell RNA - SiHa [nTPM]":"25.2","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"15.2","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"2.8","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.8","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"9.1","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"155.1","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"26.9","Blood RNA - naive B-cell [nTPM]":"0.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"376.4","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"38.0","Brain RNA - cerebellum [nTPM]":"43.3","Brain RNA - cerebral cortex [nTPM]":"18.7","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"18.8","Brain RNA - medulla oblongata [nTPM]":"55.1","Brain RNA - midbrain [nTPM]":"33.5","Brain RNA - pons [nTPM]":"45.0","Brain RNA - spinal cord [nTPM]":"31.8","Brain RNA - thalamus [nTPM]":"34.3","Brain RNA - white matter [nTPM]":"95.3","Single Cell Type RNA - Adipocytes [nTPM]":"357.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.8","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"11.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"81.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.7","Single Cell Type RNA - Bipolar cells [nTPM]":"11.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"150.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"45.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"61.5","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"575.3","Single Cell Type RNA - dendritic cells [nTPM]":"46.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"9.8","Single Cell Type RNA - Early spermatids [nTPM]":"176.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.5","Single Cell Type RNA - Endothelial cells [nTPM]":"100.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"106.5","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1531.7","Single Cell Type RNA - Fibroblasts [nTPM]":"141.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"56.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"31.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"91.0","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.0","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.5","Single Cell Type RNA - Langerhans cells [nTPM]":"23.2","Single Cell Type RNA - Late spermatids [nTPM]":"276.4","Single Cell Type RNA - Leydig cells [nTPM]":"74.3","Single Cell Type RNA - Macrophages [nTPM]":"54.9","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"14.1","Single Cell Type RNA - Muller glia cells [nTPM]":"68.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"65.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.3","Single Cell Type RNA - Paneth cells [nTPM]":"4.2","Single Cell Type RNA - Peritubular cells [nTPM]":"44.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"64.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"78.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.4","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"238.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"71.4","Single Cell Type RNA - Spermatocytes [nTPM]":"2.1","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2241.2","Single Cell Type RNA - T-cells [nTPM]":"25.1","Single Cell Type RNA - Theca cells [nTPM]":"781.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.2","Single Cell Type RNA - Urothelial cells [nTPM]":"71.8"},{"Gene":"CDKN2A","Gene synonym":["ARF","CDK4I","CDKN2","CMM2","INK4","INK4a","MLM","MTS1","p14","p14ARF","p16","p16INK4a","p19","p19Arf"],"Ensembl":"ENSG00000147889","Gene description":"Cyclin dependent kinase inhibitor 2A","Uniprot":["P42771","Q8N726"],"Chromosome":"9","Position":"21967752-21995301","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Cell cycle","rRNA processing","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"31.7","pituitary gland":"33.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"170.1","Club cells":"145.9","Early spermatids":"227.5","Late spermatids":"447.9","Pancreatic endocrine cells":"417.7","Respiratory ciliated cells":"221.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"49.9","ovarian cancer":"57.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"37.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"B-cells":"15.6","T-cells":"37.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CAPAN-2":"289.2","HEK 293":"389.7","HeLa":"311.1","SK-MEL-30":"318.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000093","CAB000445","CAB018232","HPA047838"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"18000","Blood expression cluster":"Cluster 4: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 26: Pituitary gland - Hormone signaling","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"CAB000093":"AB_442119","CAB000445":null,"CAB018232":"AB_785018","HPA047838":"AB_2680174"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.82e-7"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.19e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.17e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"8.3","Tissue RNA - bone marrow [nTPM]":"1.3","Tissue RNA - breast [nTPM]":"3.1","Tissue RNA - cerebellum [nTPM]":"5.9","Tissue RNA - cerebral cortex [nTPM]":"8.5","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"31.7","Tissue RNA - colon [nTPM]":"1.9","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"7.4","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"0.5","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"0.5","Tissue RNA - liver [nTPM]":"0.7","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"2.1","Tissue RNA - medulla oblongata [nTPM]":"7.4","Tissue RNA - midbrain [nTPM]":"5.8","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"33.7","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"7.2","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.7","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.6","Tissue RNA - seminal vesicle [nTPM]":"1.6","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"6.2","Tissue RNA - spleen [nTPM]":"5.5","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"2.5","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"2.3","Tissue RNA - white matter [nTPM]":"9.2","Cell RNA - A-431 [nTPM]":"11.8","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.7","Cell RNA - AN3-CA [nTPM]":"82.2","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.9","Cell RNA - BEWO [nTPM]":"39.1","Cell RNA - BJ [nTPM]":"15.9","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"111.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"196.0","Cell RNA - CACO-2 [nTPM]":"19.1","Cell RNA - CAPAN-2 [nTPM]":"289.2","Cell RNA - Daudi [nTPM]":"47.1","Cell RNA - EFO-21 [nTPM]":"167.7","Cell RNA - fHDF\/TERT166 [nTPM]":"9.5","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"36.0","Cell RNA - HAP1 [nTPM]":"34.3","Cell RNA - HBEC3-KT [nTPM]":"211.0","Cell RNA - HBF TERT88 [nTPM]":"91.4","Cell RNA - HDLM-2 [nTPM]":"212.2","Cell RNA - HEK 293 [nTPM]":"389.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"311.1","Cell RNA - Hep G2 [nTPM]":"13.6","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"22.4","Cell RNA - HMC-1 [nTPM]":"17.3","Cell RNA - HSkMC [nTPM]":"21.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"112.2","Cell RNA - hTERT-HME1 [nTPM]":"61.9","Cell RNA - hTERT-RPE1 [nTPM]":"236.3","Cell RNA - HUVEC TERT2 [nTPM]":"11.7","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"188.4","Cell RNA - LHCN-M2 [nTPM]":"105.7","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"1.9","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.6","Cell RNA - OE19 [nTPM]":"24.2","Cell RNA - PC-3 [nTPM]":"185.9","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"80.2","Cell RNA - RPMI-8226 [nTPM]":"166.3","Cell RNA - RPTEC TERT1 [nTPM]":"23.4","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"195.2","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"219.9","Cell RNA - SK-BR-3 [nTPM]":"36.6","Cell RNA - SK-MEL-30 [nTPM]":"318.7","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"42.8","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"39.5","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"2.6","Cell RNA - U-2197 [nTPM]":"0.3","Cell RNA - U-251 MG [nTPM]":"0.5","Cell RNA - U-266\/70 [nTPM]":"84.7","Cell RNA - U-266\/84 [nTPM]":"49.6","Cell RNA - U-698 [nTPM]":"177.8","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"62.9","Cell RNA - WM-115 [nTPM]":"1.0","Blood RNA - basophil [nTPM]":"1.5","Blood RNA - classical monocyte [nTPM]":"2.1","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"14.1","Blood RNA - memory B-cell [nTPM]":"11.1","Blood RNA - memory CD4 T-cell [nTPM]":"11.4","Blood RNA - memory CD8 T-cell [nTPM]":"17.6","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"15.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.7","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"4.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"37.4","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"8.3","Brain RNA - cerebellum [nTPM]":"5.9","Brain RNA - cerebral cortex [nTPM]":"8.5","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"7.4","Brain RNA - midbrain [nTPM]":"5.8","Brain RNA - pons [nTPM]":"7.2","Brain RNA - spinal cord [nTPM]":"6.2","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"9.2","Single Cell Type RNA - Adipocytes [nTPM]":"1.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"11.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"170.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"145.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.9","Single Cell Type RNA - dendritic cells [nTPM]":"6.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"29.7","Single Cell Type RNA - Early spermatids [nTPM]":"227.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"70.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.8","Single Cell Type RNA - Fibroblasts [nTPM]":"7.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"4.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.3","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"10.5","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"447.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"2.9","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"16.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"417.7","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"1.9","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"35.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"221.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.8","Single Cell Type RNA - Spermatocytes [nTPM]":"7.2","Single Cell Type RNA - Spermatogonia [nTPM]":"6.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.2","Single Cell Type RNA - T-cells [nTPM]":"12.7","Single Cell Type RNA - Theca cells [nTPM]":"11.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.8","Single Cell Type RNA - Urothelial cells [nTPM]":"54.4"},{"Gene":"CDKN2B","Gene synonym":["CDK4I","INK4B","MTS2","P15","p15INK4b","TP15"],"Ensembl":"ENSG00000147883","Gene description":"Cyclin dependent kinase inhibitor 2B","Uniprot":["P42772"],"Chromosome":"9","Position":"22002903-22009305","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"36.2","intestine":"30.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"240.7","Pancreatic endocrine cells":"164.5","Proximal enterocytes":"139.0","Squamous epithelial cells":"142.0","Urothelial cells":"241.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"3.3","intermediate monocyte":"3.3","non-classical monocyte":"9.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"17","RNA blood lineage specific nTPM":{"monocytes":"9.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"38.1","HaCaT":"35.0","HeLa":"33.9","hTERT-RPE1":"60.1","SiHa":"48.0","SK-MEL-30":"35.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000349","HPA052838","HPA063327"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000349":null,"HPA052838":null,"HPA063327":"AB_2684987"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.47e-6"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.49e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.7","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"2.9","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"8.6","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"1.9","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"9.1","Tissue RNA - colon [nTPM]":"22.4","Tissue RNA - duodenum [nTPM]":"21.7","Tissue RNA - endometrium 1 [nTPM]":"3.8","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"36.2","Tissue RNA - fallopian tube [nTPM]":"1.7","Tissue RNA - gallbladder [nTPM]":"2.4","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"1.6","Tissue RNA - hypothalamus [nTPM]":"2.2","Tissue RNA - kidney [nTPM]":"1.2","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"1.1","Tissue RNA - medulla oblongata [nTPM]":"2.7","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.9","Tissue RNA - pancreas [nTPM]":"1.2","Tissue RNA - parathyroid gland [nTPM]":"3.3","Tissue RNA - pituitary gland [nTPM]":"3.5","Tissue RNA - placenta [nTPM]":"2.3","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"3.6","Tissue RNA - rectum [nTPM]":"19.7","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"6.7","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"7.2","Tissue RNA - skin 1 [nTPM]":"12.9","Tissue RNA - small intestine [nTPM]":"30.9","Tissue RNA - smooth muscle [nTPM]":"2.1","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"4.6","Tissue RNA - stomach 1 [nTPM]":"6.0","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"0.8","Tissue RNA - thyroid gland [nTPM]":"1.1","Tissue RNA - tongue [nTPM]":"1.1","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"20.2","Tissue RNA - white matter [nTPM]":"2.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"28.2","Cell RNA - ASC TERT1 [nTPM]":"38.1","Cell RNA - BEWO [nTPM]":"0.7","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"12.6","Cell RNA - CACO-2 [nTPM]":"3.6","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"35.0","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"6.9","Cell RNA - HBF TERT88 [nTPM]":"5.5","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"9.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"33.9","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"14.4","Cell RNA - HL-60 [nTPM]":"1.1","Cell RNA - HMC-1 [nTPM]":"6.1","Cell RNA - HSkMC [nTPM]":"8.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.5","Cell RNA - hTERT-HME1 [nTPM]":"25.8","Cell RNA - hTERT-RPE1 [nTPM]":"60.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"17.1","Cell RNA - LHCN-M2 [nTPM]":"7.3","Cell RNA - MCF7 [nTPM]":"2.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"1.7","Cell RNA - PC-3 [nTPM]":"19.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.4","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"10.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"5.4","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"48.0","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"35.7","Cell RNA - SuSa [nTPM]":"25.8","Cell RNA - T-47d [nTPM]":"3.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.7","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"13.5","Cell RNA - U-266\/84 [nTPM]":"8.4","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"9.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"1.9","Brain RNA - hippocampal formation [nTPM]":"1.6","Brain RNA - hypothalamus [nTPM]":"2.2","Brain RNA - medulla oblongata [nTPM]":"2.7","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"2.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"2.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"37.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"3.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"240.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"57.7","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.5","Single Cell Type RNA - Endothelial cells [nTPM]":"4.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.8","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"30.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"37.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"31.6","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.6","Single Cell Type RNA - Langerhans cells [nTPM]":"3.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"3.2","Single Cell Type RNA - Muller glia cells [nTPM]":"4.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"164.5","Single Cell Type RNA - Paneth cells [nTPM]":"75.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"2.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"65.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.9","Single Cell Type RNA - Spermatocytes [nTPM]":"13.8","Single Cell Type RNA - Spermatogonia [nTPM]":"3.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"142.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"2.9","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.3","Single Cell Type RNA - Urothelial cells [nTPM]":"241.6"},{"Gene":"CDX2","Gene synonym":["CDX3"],"Ensembl":"ENSG00000165556","Gene description":"Caudal type homeobox 2","Uniprot":["Q99626"],"Chromosome":"13","Position":"27960918-27969315","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"intestine":"41.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"287.5","Intestinal goblet cells":"214.5","Paneth cells":"181.7","Proximal enterocytes":"226.9","Undifferentiated cells":"194.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"6","RNA cancer specific FPKM":{"colorectal cancer":"63.7"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"CACO-2":"14.4","CAPAN-2":"4.8","HEK 293":"7.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002221","HPA045669","HPA049580"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 9: Intestine - Unknown function","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB002221":"AB_563649","HPA045669":"AB_2679413","HPA049580":"AB_2680823"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.41e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.11e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-4"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"41.0","Tissue RNA - duodenum [nTPM]":"28.6","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"31.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"35.9","Tissue RNA - smooth muscle [nTPM]":"1.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"14.4","Cell RNA - CAPAN-2 [nTPM]":"4.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"7.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.7","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.6","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.9","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"287.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"28.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"62.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"214.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"6.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"181.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"226.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.4","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"194.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"CEBPA","Gene synonym":["C\/EBP-alpha","CEBP"],"Ensembl":"ENSG00000245848","Gene description":"CCAAT enhancer binding protein alpha","Uniprot":["P49715"],"Chromosome":"19","Position":"33299934-33302534","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"98.7","liver":"194.7","skin 1":"118.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"91.6","Hepatocytes":"106.5","Hofbauer cells":"87.0","Suprabasal keratinocytes":"171.8","Syncytiotrophoblasts":"212.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"70.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"16.0","classical monocyte":"7.1","intermediate monocyte":"12.3","myeloid DC":"5.1","non-classical monocyte":"15.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"15","RNA blood lineage specific nTPM":{"dendritic cells":"5.1","granulocytes":"16.0","monocytes":"15.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"196.9","Hep G2":"110.9","NB-4":"114.1","THP-1":"407.7","U-937":"130.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA052734","HPA065037","HPA067937"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA052734":"AB_2681931","HPA065037":"AB_2685410","HPA067937":"AB_2685927"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.45e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Tissue RNA - adipose tissue [nTPM]":"98.7","Tissue RNA - adrenal gland [nTPM]":"2.9","Tissue RNA - amygdala [nTPM]":"16.2","Tissue RNA - appendix [nTPM]":"5.7","Tissue RNA - basal ganglia [nTPM]":"17.9","Tissue RNA - bone marrow [nTPM]":"22.6","Tissue RNA - breast [nTPM]":"67.7","Tissue RNA - cerebellum [nTPM]":"18.3","Tissue RNA - cerebral cortex [nTPM]":"26.9","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"10.4","Tissue RNA - colon [nTPM]":"21.0","Tissue RNA - duodenum [nTPM]":"21.2","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"0.8","Tissue RNA - esophagus [nTPM]":"20.9","Tissue RNA - fallopian tube [nTPM]":"4.3","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"15.7","Tissue RNA - hypothalamus [nTPM]":"18.8","Tissue RNA - kidney [nTPM]":"3.6","Tissue RNA - liver [nTPM]":"194.7","Tissue RNA - lung [nTPM]":"25.5","Tissue RNA - lymph node [nTPM]":"9.1","Tissue RNA - medulla oblongata [nTPM]":"27.4","Tissue RNA - midbrain [nTPM]":"22.4","Tissue RNA - ovary [nTPM]":"1.3","Tissue RNA - pancreas [nTPM]":"9.7","Tissue RNA - parathyroid gland [nTPM]":"26.8","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"16.0","Tissue RNA - pons [nTPM]":"21.3","Tissue RNA - prostate [nTPM]":"8.8","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"9.8","Tissue RNA - seminal vesicle [nTPM]":"3.4","Tissue RNA - skeletal muscle [nTPM]":"19.1","Tissue RNA - skin 1 [nTPM]":"118.7","Tissue RNA - small intestine [nTPM]":"20.8","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"25.7","Tissue RNA - spleen [nTPM]":"7.7","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"24.5","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"4.5","Tissue RNA - tonsil [nTPM]":"6.3","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"34.8","Cell RNA - A-431 [nTPM]":"2.5","Cell RNA - A549 [nTPM]":"5.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"7.1","Cell RNA - ASC diff [nTPM]":"55.8","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"196.9","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"24.8","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"5.8","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"35.8","Cell RNA - HEK 293 [nTPM]":"7.2","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"110.9","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"36.6","Cell RNA - HMC-1 [nTPM]":"42.1","Cell RNA - HSkMC [nTPM]":"2.2","Cell RNA - hTCEpi [nTPM]":"25.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"114.1","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"61.8","Cell RNA - PC-3 [nTPM]":"2.7","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"17.7","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"1.7","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"6.2","Cell RNA - T-47d [nTPM]":"13.7","Cell RNA - THP-1 [nTPM]":"407.7","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"130.9","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"16.0","Blood RNA - classical monocyte [nTPM]":"7.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"0.7","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"5.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"15.7","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"16.2","Brain RNA - basal ganglia [nTPM]":"17.9","Brain RNA - cerebellum [nTPM]":"18.3","Brain RNA - cerebral cortex [nTPM]":"26.9","Brain RNA - hippocampal formation [nTPM]":"15.7","Brain RNA - hypothalamus [nTPM]":"18.8","Brain RNA - medulla oblongata [nTPM]":"27.4","Brain RNA - midbrain [nTPM]":"22.4","Brain RNA - pons [nTPM]":"21.3","Brain RNA - spinal cord [nTPM]":"25.7","Brain RNA - thalamus [nTPM]":"24.5","Brain RNA - white matter [nTPM]":"34.8","Single Cell Type RNA - Adipocytes [nTPM]":"5.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"37.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"5.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.3","Single Cell Type RNA - dendritic cells [nTPM]":"14.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"91.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.8","Single Cell Type RNA - Endothelial cells [nTPM]":"4.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"5.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"44.3","Single Cell Type RNA - Fibroblasts [nTPM]":"9.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"106.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"87.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"35.0","Single Cell Type RNA - Langerhans cells [nTPM]":"27.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"42.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"28.2","Single Cell Type RNA - Muller glia cells [nTPM]":"8.4","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.9","Single Cell Type RNA - Paneth cells [nTPM]":"30.6","Single Cell Type RNA - Peritubular cells [nTPM]":"1.5","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"42.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"171.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"212.3","Single Cell Type RNA - T-cells [nTPM]":"5.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.5","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"CREBBP","Gene synonym":["CBP","KAT3A","RSTS","RTS"],"Ensembl":"ENSG00000005339","Gene description":"CREB binding protein","Uniprot":["Q92793"],"Chromosome":"16","Position":"3725054-3880713","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004212","HPA055861"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB004212":"AB_626817","HPA055861":"AB_2682948"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.84e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.24e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.23e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.4","Tissue RNA - adrenal gland [nTPM]":"10.6","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"17.1","Tissue RNA - basal ganglia [nTPM]":"5.2","Tissue RNA - bone marrow [nTPM]":"52.9","Tissue RNA - breast [nTPM]":"16.8","Tissue RNA - cerebellum [nTPM]":"25.4","Tissue RNA - cerebral cortex [nTPM]":"11.5","Tissue RNA - cervix [nTPM]":"20.9","Tissue RNA - choroid plexus [nTPM]":"3.7","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"12.5","Tissue RNA - endometrium 1 [nTPM]":"26.5","Tissue RNA - epididymis [nTPM]":"12.4","Tissue RNA - esophagus [nTPM]":"16.5","Tissue RNA - fallopian tube [nTPM]":"22.4","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"14.4","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"14.3","Tissue RNA - lung [nTPM]":"15.9","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"37.3","Tissue RNA - pancreas [nTPM]":"29.7","Tissue RNA - parathyroid gland [nTPM]":"18.5","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"16.9","Tissue RNA - pons [nTPM]":"2.9","Tissue RNA - prostate [nTPM]":"16.1","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"13.8","Tissue RNA - salivary gland [nTPM]":"17.2","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"29.6","Tissue RNA - skin 1 [nTPM]":"21.0","Tissue RNA - small intestine [nTPM]":"16.4","Tissue RNA - smooth muscle [nTPM]":"19.6","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"21.0","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"33.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"29.1","Tissue RNA - thyroid gland [nTPM]":"23.3","Tissue RNA - tongue [nTPM]":"28.9","Tissue RNA - tonsil [nTPM]":"20.7","Tissue RNA - urinary bladder [nTPM]":"16.6","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"12.3","Cell RNA - A549 [nTPM]":"31.0","Cell RNA - AF22 [nTPM]":"39.3","Cell RNA - AN3-CA [nTPM]":"17.4","Cell RNA - ASC diff [nTPM]":"23.5","Cell RNA - ASC TERT1 [nTPM]":"23.1","Cell RNA - BEWO [nTPM]":"20.4","Cell RNA - BJ [nTPM]":"17.4","Cell RNA - BJ hTERT+ [nTPM]":"28.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"29.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"28.2","Cell RNA - CACO-2 [nTPM]":"28.2","Cell RNA - CAPAN-2 [nTPM]":"22.4","Cell RNA - Daudi [nTPM]":"33.7","Cell RNA - EFO-21 [nTPM]":"20.1","Cell RNA - fHDF\/TERT166 [nTPM]":"33.3","Cell RNA - GAMG [nTPM]":"18.7","Cell RNA - HaCaT [nTPM]":"23.2","Cell RNA - HAP1 [nTPM]":"45.7","Cell RNA - HBEC3-KT [nTPM]":"14.2","Cell RNA - HBF TERT88 [nTPM]":"32.9","Cell RNA - HDLM-2 [nTPM]":"57.5","Cell RNA - HEK 293 [nTPM]":"18.5","Cell RNA - HEL [nTPM]":"26.6","Cell RNA - HeLa [nTPM]":"29.2","Cell RNA - Hep G2 [nTPM]":"17.9","Cell RNA - HHSteC [nTPM]":"26.0","Cell RNA - HL-60 [nTPM]":"26.9","Cell RNA - HMC-1 [nTPM]":"36.5","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"14.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.5","Cell RNA - hTERT-HME1 [nTPM]":"38.9","Cell RNA - hTERT-RPE1 [nTPM]":"18.0","Cell RNA - HUVEC TERT2 [nTPM]":"22.3","Cell RNA - JURKAT [nTPM]":"17.0","Cell RNA - K-562 [nTPM]":"30.9","Cell RNA - Karpas-707 [nTPM]":"44.8","Cell RNA - LHCN-M2 [nTPM]":"16.0","Cell RNA - MCF7 [nTPM]":"42.0","Cell RNA - MOLT-4 [nTPM]":"17.9","Cell RNA - NB-4 [nTPM]":"13.0","Cell RNA - NTERA-2 [nTPM]":"32.3","Cell RNA - OE19 [nTPM]":"11.7","Cell RNA - PC-3 [nTPM]":"12.7","Cell RNA - REH [nTPM]":"83.4","Cell RNA - RH-30 [nTPM]":"31.1","Cell RNA - RPMI-8226 [nTPM]":"26.1","Cell RNA - RPTEC TERT1 [nTPM]":"11.2","Cell RNA - RT4 [nTPM]":"16.2","Cell RNA - SCLC-21H [nTPM]":"32.6","Cell RNA - SH-SY5Y [nTPM]":"21.5","Cell RNA - SiHa [nTPM]":"29.5","Cell RNA - SK-BR-3 [nTPM]":"28.7","Cell RNA - SK-MEL-30 [nTPM]":"16.8","Cell RNA - SuSa [nTPM]":"25.3","Cell RNA - T-47d [nTPM]":"25.6","Cell RNA - THP-1 [nTPM]":"25.9","Cell RNA - TIME [nTPM]":"34.7","Cell RNA - U-138 MG [nTPM]":"35.5","Cell RNA - U-2 OS [nTPM]":"35.2","Cell RNA - U-2197 [nTPM]":"18.4","Cell RNA - U-251 MG [nTPM]":"16.0","Cell RNA - U-266\/70 [nTPM]":"20.8","Cell RNA - U-266\/84 [nTPM]":"24.3","Cell RNA - U-698 [nTPM]":"63.7","Cell RNA - U-87 MG [nTPM]":"7.2","Cell RNA - U-937 [nTPM]":"15.8","Cell RNA - WM-115 [nTPM]":"25.6","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.3","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"6.7","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"2.9","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.9","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"5.2","Brain RNA - cerebellum [nTPM]":"25.4","Brain RNA - cerebral cortex [nTPM]":"11.5","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"2.9","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.6","Single Cell Type RNA - Astrocytes [nTPM]":"91.1","Single Cell Type RNA - B-cells [nTPM]":"38.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.3","Single Cell Type RNA - Bipolar cells [nTPM]":"34.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"28.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"17.4","Single Cell Type RNA - dendritic cells [nTPM]":"50.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"20.9","Single Cell Type RNA - Early spermatids [nTPM]":"43.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"20.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"11.3","Single Cell Type RNA - Fibroblasts [nTPM]":"39.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.5","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"53.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"29.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.9","Single Cell Type RNA - Horizontal cells [nTPM]":"28.6","Single Cell Type RNA - Inhibitory neurons [nTPM]":"89.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"25.3","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"44.0","Single Cell Type RNA - Langerhans cells [nTPM]":"42.8","Single Cell Type RNA - Late spermatids [nTPM]":"80.2","Single Cell Type RNA - Leydig cells [nTPM]":"56.5","Single Cell Type RNA - Macrophages [nTPM]":"49.0","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"87.1","Single Cell Type RNA - monocytes [nTPM]":"52.5","Single Cell Type RNA - Muller glia cells [nTPM]":"34.5","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"111.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"101.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"27.5","Single Cell Type RNA - Paneth cells [nTPM]":"19.5","Single Cell Type RNA - Peritubular cells [nTPM]":"51.1","Single Cell Type RNA - Plasma cells [nTPM]":"35.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"17.6","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"75.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"44.9","Single Cell Type RNA - Spermatocytes [nTPM]":"35.1","Single Cell Type RNA - Spermatogonia [nTPM]":"42.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"58.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.8","Single Cell Type RNA - T-cells [nTPM]":"44.2","Single Cell Type RNA - Theca cells [nTPM]":"36.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.6","Single Cell Type RNA - Urothelial cells [nTPM]":"44.2"},{"Gene":"CRLF2","Gene synonym":["CRL2","TSLPR"],"Ensembl":"ENSG00000205755","Gene description":"Cytokine receptor like factor 2","Uniprot":["Q9HC73"],"Chromosome":"X","Position":"1187549-1212723","Protein class":["Cancer-related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1.8","gallbladder":"1.3","lymphoid tissue":"1.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"monocytes":"100.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"thyroid cancer":"1.0"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"plasmacytoid DC":"1.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"13","RNA blood lineage specific nTPM":{"dendritic cells":"1.2"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HMC-1":"16.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 3: Monocytes - Immune response regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.02e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-6"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.1","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.3","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.3","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.3","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.1","Tissue RNA - tonsil [nTPM]":"0.5","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.8","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"2.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"1.7","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"16.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"3.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.9","Cell RNA - U-698 [nTPM]":"3.4","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"20.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"1.1","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.8","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"100.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"CRTC1","Gene synonym":["FLJ14027","KIAA0616","MECT1","TORC1"],"Ensembl":"ENSG00000105662","Gene description":"CREB regulated transcription coactivator 1","Uniprot":["Q6UUV9"],"Chromosome":"19","Position":"18683678-18782333","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"37.4","Horizontal cells":"43.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"203","RNA brain regional specific nTPM":{"amygdala":"14.2","basal ganglia":"11.4","cerebellum":"27.1","cerebral cortex":"24.3","hippocampal formation":"24.5"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA022035","HPA063619"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 35: Non-specific - Unknown function","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":["Plasma membrane","Cytosol"],"Antibody RRID":{"HPA022035":"AB_1847255","HPA063619":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.94e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.62e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.80e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.83e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"14.2","Tissue RNA - appendix [nTPM]":"5.2","Tissue RNA - basal ganglia [nTPM]":"11.4","Tissue RNA - bone marrow [nTPM]":"2.1","Tissue RNA - breast [nTPM]":"8.2","Tissue RNA - cerebellum [nTPM]":"27.1","Tissue RNA - cerebral cortex [nTPM]":"24.3","Tissue RNA - cervix [nTPM]":"11.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"8.9","Tissue RNA - duodenum [nTPM]":"4.0","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"3.4","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"3.2","Tissue RNA - heart muscle [nTPM]":"10.5","Tissue RNA - hippocampal formation [nTPM]":"24.5","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"9.4","Tissue RNA - pancreas [nTPM]":"9.8","Tissue RNA - parathyroid gland [nTPM]":"4.7","Tissue RNA - pituitary gland [nTPM]":"23.7","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"11.6","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"4.4","Tissue RNA - salivary gland [nTPM]":"7.3","Tissue RNA - seminal vesicle [nTPM]":"5.1","Tissue RNA - skeletal muscle [nTPM]":"14.4","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"8.5","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"9.6","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"11.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"3.6","Tissue RNA - thyroid gland [nTPM]":"14.4","Tissue RNA - tongue [nTPM]":"3.6","Tissue RNA - tonsil [nTPM]":"2.2","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"5.2","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"6.7","Cell RNA - AN3-CA [nTPM]":"10.7","Cell RNA - ASC diff [nTPM]":"6.3","Cell RNA - ASC TERT1 [nTPM]":"4.5","Cell RNA - BEWO [nTPM]":"18.6","Cell RNA - BJ [nTPM]":"5.4","Cell RNA - BJ hTERT+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.8","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"6.6","Cell RNA - Daudi [nTPM]":"7.1","Cell RNA - EFO-21 [nTPM]":"11.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.2","Cell RNA - GAMG [nTPM]":"3.9","Cell RNA - HaCaT [nTPM]":"5.5","Cell RNA - HAP1 [nTPM]":"2.1","Cell RNA - HBEC3-KT [nTPM]":"3.5","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"15.1","Cell RNA - HEL [nTPM]":"6.0","Cell RNA - HeLa [nTPM]":"7.8","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"8.3","Cell RNA - HMC-1 [nTPM]":"16.3","Cell RNA - HSkMC [nTPM]":"7.8","Cell RNA - hTCEpi [nTPM]":"2.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.4","Cell RNA - hTERT-HME1 [nTPM]":"1.3","Cell RNA - hTERT-RPE1 [nTPM]":"6.8","Cell RNA - HUVEC TERT2 [nTPM]":"3.1","Cell RNA - JURKAT [nTPM]":"7.2","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"6.3","Cell RNA - LHCN-M2 [nTPM]":"3.0","Cell RNA - MCF7 [nTPM]":"15.2","Cell RNA - MOLT-4 [nTPM]":"5.7","Cell RNA - NB-4 [nTPM]":"10.0","Cell RNA - NTERA-2 [nTPM]":"8.8","Cell RNA - OE19 [nTPM]":"2.7","Cell RNA - PC-3 [nTPM]":"13.1","Cell RNA - REH [nTPM]":"8.7","Cell RNA - RH-30 [nTPM]":"2.9","Cell RNA - RPMI-8226 [nTPM]":"8.1","Cell RNA - RPTEC TERT1 [nTPM]":"3.2","Cell RNA - RT4 [nTPM]":"8.0","Cell RNA - SCLC-21H [nTPM]":"12.1","Cell RNA - SH-SY5Y [nTPM]":"10.7","Cell RNA - SiHa [nTPM]":"6.0","Cell RNA - SK-BR-3 [nTPM]":"5.8","Cell RNA - SK-MEL-30 [nTPM]":"7.0","Cell RNA - SuSa [nTPM]":"2.2","Cell RNA - T-47d [nTPM]":"6.6","Cell RNA - THP-1 [nTPM]":"5.2","Cell RNA - TIME [nTPM]":"5.4","Cell RNA - U-138 MG [nTPM]":"6.0","Cell RNA - U-2 OS [nTPM]":"9.1","Cell RNA - U-2197 [nTPM]":"10.8","Cell RNA - U-251 MG [nTPM]":"6.4","Cell RNA - U-266\/70 [nTPM]":"4.4","Cell RNA - U-266\/84 [nTPM]":"3.6","Cell RNA - U-698 [nTPM]":"4.6","Cell RNA - U-87 MG [nTPM]":"6.9","Cell RNA - U-937 [nTPM]":"8.6","Cell RNA - WM-115 [nTPM]":"4.6","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"14.2","Brain RNA - basal ganglia [nTPM]":"11.4","Brain RNA - cerebellum [nTPM]":"27.1","Brain RNA - cerebral cortex [nTPM]":"24.3","Brain RNA - hippocampal formation [nTPM]":"24.5","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"31.0","Single Cell Type RNA - B-cells [nTPM]":"6.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"29.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"3.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.7","Single Cell Type RNA - dendritic cells [nTPM]":"7.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"4.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.0","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.7","Single Cell Type RNA - Fibroblasts [nTPM]":"7.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"14.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"4.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.8","Single Cell Type RNA - Horizontal cells [nTPM]":"43.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.1","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"6.0","Single Cell Type RNA - Langerhans cells [nTPM]":"4.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"9.3","Single Cell Type RNA - Macrophages [nTPM]":"6.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"14.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.6","Single Cell Type RNA - Spermatocytes [nTPM]":"2.9","Single Cell Type RNA - Spermatogonia [nTPM]":"8.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"5.1","Single Cell Type RNA - Theca cells [nTPM]":"8.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.6"},{"Gene":"CSF1R","Gene synonym":["C-FMS","CD115","CSFR","FMS"],"Ensembl":"ENSG00000182578","Gene description":"Colony stimulating factor 1 receptor","Uniprot":["P07333"],"Chromosome":"5","Position":"150053291-150113372","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Neurodegeneration","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"113.3","placenta":"103.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Extravillous trophoblasts":"103.2","Hofbauer cells":"340.4","Kupffer cells":"291.2","Langerhans cells":"73.4","Macrophages":"196.3","Microglial cells":"134.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"444.6","non-classical monocyte":"646.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"monocytes":"646.9"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"BEWO":"123.0","SK-BR-3":"47.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008970","HPA012323"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB008970":null,"HPA012323":"AB_1848977"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.92e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"51.3","Tissue RNA - adrenal gland [nTPM]":"31.0","Tissue RNA - amygdala [nTPM]":"19.6","Tissue RNA - appendix [nTPM]":"75.1","Tissue RNA - basal ganglia [nTPM]":"17.1","Tissue RNA - bone marrow [nTPM]":"5.6","Tissue RNA - breast [nTPM]":"19.3","Tissue RNA - cerebellum [nTPM]":"20.2","Tissue RNA - cerebral cortex [nTPM]":"21.4","Tissue RNA - cervix [nTPM]":"21.6","Tissue RNA - choroid plexus [nTPM]":"19.3","Tissue RNA - colon [nTPM]":"21.9","Tissue RNA - duodenum [nTPM]":"24.3","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"5.8","Tissue RNA - esophagus [nTPM]":"21.0","Tissue RNA - fallopian tube [nTPM]":"17.2","Tissue RNA - gallbladder [nTPM]":"40.6","Tissue RNA - heart muscle [nTPM]":"16.6","Tissue RNA - hippocampal formation [nTPM]":"19.8","Tissue RNA - hypothalamus [nTPM]":"33.8","Tissue RNA - kidney [nTPM]":"7.1","Tissue RNA - liver [nTPM]":"27.5","Tissue RNA - lung [nTPM]":"36.6","Tissue RNA - lymph node [nTPM]":"54.4","Tissue RNA - medulla oblongata [nTPM]":"41.4","Tissue RNA - midbrain [nTPM]":"35.5","Tissue RNA - ovary [nTPM]":"12.7","Tissue RNA - pancreas [nTPM]":"9.9","Tissue RNA - parathyroid gland [nTPM]":"11.8","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"103.3","Tissue RNA - pons [nTPM]":"40.1","Tissue RNA - prostate [nTPM]":"9.1","Tissue RNA - rectum [nTPM]":"21.5","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"10.1","Tissue RNA - seminal vesicle [nTPM]":"20.8","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"41.9","Tissue RNA - spinal cord [nTPM]":"36.6","Tissue RNA - spleen [nTPM]":"113.3","Tissue RNA - stomach 1 [nTPM]":"21.0","Tissue RNA - testis [nTPM]":"7.0","Tissue RNA - thalamus [nTPM]":"40.6","Tissue RNA - thymus [nTPM]":"14.3","Tissue RNA - thyroid gland [nTPM]":"6.0","Tissue RNA - tongue [nTPM]":"11.8","Tissue RNA - tonsil [nTPM]":"21.7","Tissue RNA - urinary bladder [nTPM]":"42.6","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"67.6","Cell RNA - A-431 [nTPM]":"4.5","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.9","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"123.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"5.9","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.3","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"6.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"6.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"47.8","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"20.7","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.8","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"3.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"6.6","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"138.4","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"444.6","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.4","Blood RNA - myeloid DC [nTPM]":"139.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"21.6","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"646.9","Blood RNA - plasmacytoid DC [nTPM]":"11.1","Blood RNA - T-reg [nTPM]":"0.5","Blood RNA - total PBMC [nTPM]":"132.7","Brain RNA - amygdala [nTPM]":"19.6","Brain RNA - basal ganglia [nTPM]":"17.1","Brain RNA - cerebellum [nTPM]":"20.2","Brain RNA - cerebral cortex [nTPM]":"21.4","Brain RNA - hippocampal formation [nTPM]":"19.8","Brain RNA - hypothalamus [nTPM]":"33.8","Brain RNA - medulla oblongata [nTPM]":"41.4","Brain RNA - midbrain [nTPM]":"35.5","Brain RNA - pons [nTPM]":"40.1","Brain RNA - spinal cord [nTPM]":"36.6","Brain RNA - thalamus [nTPM]":"40.6","Brain RNA - white matter [nTPM]":"67.6","Single Cell Type RNA - Adipocytes [nTPM]":"2.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.2","Single Cell Type RNA - dendritic cells [nTPM]":"2.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"103.2","Single Cell Type RNA - Fibroblasts [nTPM]":"2.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"340.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"291.2","Single Cell Type RNA - Langerhans cells [nTPM]":"73.4","Single Cell Type RNA - Late spermatids [nTPM]":"5.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"196.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"134.9","Single Cell Type RNA - monocytes [nTPM]":"39.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.7","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.4","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"2.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"CSF3R","Gene synonym":["CD114","GCSFR"],"Ensembl":"ENSG00000119535","Gene description":"Colony stimulating factor 3 receptor","Uniprot":["Q99062"],"Chromosome":"1","Position":"36466043-36483278","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"bone marrow":"379.7","lung":"136.7","lymphoid tissue":"375.6","placenta":"105.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"230.8","Cytotrophoblasts":"423.8","Kupffer cells":"177.7","monocytes":"197.6","Syncytiotrophoblasts":"1194.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"neutrophil":"1962.3"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"1962.3"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"18","RNA cell line specific nTPM":{"BEWO":"70.8","NB-4":"20.3","THP-1":"50.3","U-937":"47.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017116","HPA048086"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"150000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB017116":null,"HPA048086":"AB_2680257"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.57e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.72e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.33e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.79e-4"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Tissue RNA - adipose tissue [nTPM]":"36.2","Tissue RNA - adrenal gland [nTPM]":"7.1","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"148.2","Tissue RNA - basal ganglia [nTPM]":"5.6","Tissue RNA - bone marrow [nTPM]":"379.7","Tissue RNA - breast [nTPM]":"13.0","Tissue RNA - cerebellum [nTPM]":"6.7","Tissue RNA - cerebral cortex [nTPM]":"19.0","Tissue RNA - cervix [nTPM]":"5.2","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"3.1","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"5.6","Tissue RNA - fallopian tube [nTPM]":"31.5","Tissue RNA - gallbladder [nTPM]":"15.8","Tissue RNA - heart muscle [nTPM]":"14.6","Tissue RNA - hippocampal formation [nTPM]":"5.5","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"9.7","Tissue RNA - liver [nTPM]":"22.9","Tissue RNA - lung [nTPM]":"136.7","Tissue RNA - lymph node [nTPM]":"7.3","Tissue RNA - medulla oblongata [nTPM]":"10.3","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"3.2","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"1.6","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"105.1","Tissue RNA - pons [nTPM]":"11.4","Tissue RNA - prostate [nTPM]":"7.5","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"3.6","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"9.6","Tissue RNA - spleen [nTPM]":"375.6","Tissue RNA - stomach 1 [nTPM]":"9.9","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"10.7","Tissue RNA - thymus [nTPM]":"5.7","Tissue RNA - thyroid gland [nTPM]":"5.8","Tissue RNA - tongue [nTPM]":"21.7","Tissue RNA - tonsil [nTPM]":"2.7","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"70.8","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.5","Cell RNA - HHSteC [nTPM]":"1.6","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"20.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"50.3","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"47.8","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"280.8","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"56.8","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"97.2","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"1962.3","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"24.1","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"158.4","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"5.6","Brain RNA - cerebellum [nTPM]":"6.7","Brain RNA - cerebral cortex [nTPM]":"19.0","Brain RNA - hippocampal formation [nTPM]":"5.5","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"10.3","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"11.4","Brain RNA - spinal cord [nTPM]":"9.6","Brain RNA - thalamus [nTPM]":"10.7","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"230.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"423.8","Single Cell Type RNA - dendritic cells [nTPM]":"2.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.4","Single Cell Type RNA - Endothelial cells [nTPM]":"4.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"47.3","Single Cell Type RNA - Fibroblasts [nTPM]":"8.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"18.9","Single Cell Type RNA - Granulosa cells [nTPM]":"1.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"64.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"177.7","Single Cell Type RNA - Langerhans cells [nTPM]":"39.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"111.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"77.8","Single Cell Type RNA - monocytes [nTPM]":"197.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1194.8","Single Cell Type RNA - T-cells [nTPM]":"4.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"3.0"},{"Gene":"CTNNB1","Gene synonym":["armadillo","beta-catenin","CTNNB"],"Ensembl":"ENSG00000168036","Gene description":"Catenin beta 1","Uniprot":["P35222"],"Chromosome":"3","Position":"41194741-41260096","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell adhesion","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation","Wnt signaling pathway"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Syncytiotrophoblasts":"539.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000108","CAB001950","HPA029159","HPA029160"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB000108":null,"CAB001950":null,"HPA029159":"AB_10599619","HPA029160":"AB_10600996"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.54e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"130.8","Tissue RNA - adrenal gland [nTPM]":"112.2","Tissue RNA - amygdala [nTPM]":"106.7","Tissue RNA - appendix [nTPM]":"98.7","Tissue RNA - basal ganglia [nTPM]":"85.3","Tissue RNA - bone marrow [nTPM]":"162.4","Tissue RNA - breast [nTPM]":"194.3","Tissue RNA - cerebellum [nTPM]":"147.8","Tissue RNA - cerebral cortex [nTPM]":"87.5","Tissue RNA - cervix [nTPM]":"179.4","Tissue RNA - choroid plexus [nTPM]":"94.7","Tissue RNA - colon [nTPM]":"141.2","Tissue RNA - duodenum [nTPM]":"136.9","Tissue RNA - endometrium 1 [nTPM]":"149.4","Tissue RNA - epididymis [nTPM]":"84.4","Tissue RNA - esophagus [nTPM]":"113.7","Tissue RNA - fallopian tube [nTPM]":"131.0","Tissue RNA - gallbladder [nTPM]":"121.8","Tissue RNA - heart muscle [nTPM]":"109.9","Tissue RNA - hippocampal formation [nTPM]":"88.1","Tissue RNA - hypothalamus [nTPM]":"105.3","Tissue RNA - kidney [nTPM]":"106.5","Tissue RNA - liver [nTPM]":"147.9","Tissue RNA - lung [nTPM]":"132.9","Tissue RNA - lymph node [nTPM]":"81.9","Tissue RNA - medulla oblongata [nTPM]":"101.3","Tissue RNA - midbrain [nTPM]":"112.9","Tissue RNA - ovary [nTPM]":"173.9","Tissue RNA - pancreas [nTPM]":"93.3","Tissue RNA - parathyroid gland [nTPM]":"137.2","Tissue RNA - pituitary gland [nTPM]":"84.7","Tissue RNA - placenta [nTPM]":"200.0","Tissue RNA - pons [nTPM]":"94.0","Tissue RNA - prostate [nTPM]":"132.3","Tissue RNA - rectum [nTPM]":"134.5","Tissue RNA - retina [nTPM]":"88.8","Tissue RNA - salivary gland [nTPM]":"110.9","Tissue RNA - seminal vesicle [nTPM]":"126.3","Tissue RNA - skeletal muscle [nTPM]":"87.3","Tissue RNA - skin 1 [nTPM]":"99.0","Tissue RNA - small intestine [nTPM]":"142.9","Tissue RNA - smooth muscle [nTPM]":"178.4","Tissue RNA - spinal cord [nTPM]":"104.9","Tissue RNA - spleen [nTPM]":"92.5","Tissue RNA - stomach 1 [nTPM]":"81.8","Tissue RNA - testis [nTPM]":"59.5","Tissue RNA - thalamus [nTPM]":"129.4","Tissue RNA - thymus [nTPM]":"95.6","Tissue RNA - thyroid gland [nTPM]":"140.6","Tissue RNA - tongue [nTPM]":"89.9","Tissue RNA - tonsil [nTPM]":"99.5","Tissue RNA - urinary bladder [nTPM]":"158.3","Tissue RNA - vagina [nTPM]":"109.3","Tissue RNA - white matter [nTPM]":"108.4","Cell RNA - A-431 [nTPM]":"161.6","Cell RNA - A549 [nTPM]":"210.0","Cell RNA - AF22 [nTPM]":"423.6","Cell RNA - AN3-CA [nTPM]":"242.8","Cell RNA - ASC diff [nTPM]":"226.9","Cell RNA - ASC TERT1 [nTPM]":"184.7","Cell RNA - BEWO [nTPM]":"333.8","Cell RNA - BJ [nTPM]":"179.6","Cell RNA - BJ hTERT+ [nTPM]":"249.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"288.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"284.3","Cell RNA - CACO-2 [nTPM]":"146.3","Cell RNA - CAPAN-2 [nTPM]":"224.0","Cell RNA - Daudi [nTPM]":"131.7","Cell RNA - EFO-21 [nTPM]":"157.8","Cell RNA - fHDF\/TERT166 [nTPM]":"314.1","Cell RNA - GAMG [nTPM]":"129.0","Cell RNA - HaCaT [nTPM]":"119.6","Cell RNA - HAP1 [nTPM]":"315.8","Cell RNA - HBEC3-KT [nTPM]":"510.0","Cell RNA - HBF TERT88 [nTPM]":"306.2","Cell RNA - HDLM-2 [nTPM]":"123.3","Cell RNA - HEK 293 [nTPM]":"215.7","Cell RNA - HEL [nTPM]":"215.5","Cell RNA - HeLa [nTPM]":"261.0","Cell RNA - Hep G2 [nTPM]":"523.7","Cell RNA - HHSteC [nTPM]":"169.5","Cell RNA - HL-60 [nTPM]":"121.8","Cell RNA - HMC-1 [nTPM]":"99.1","Cell RNA - HSkMC [nTPM]":"271.6","Cell RNA - hTCEpi [nTPM]":"226.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"345.5","Cell RNA - hTERT-HME1 [nTPM]":"208.7","Cell RNA - hTERT-RPE1 [nTPM]":"235.7","Cell RNA - HUVEC TERT2 [nTPM]":"258.1","Cell RNA - JURKAT [nTPM]":"63.0","Cell RNA - K-562 [nTPM]":"153.7","Cell RNA - Karpas-707 [nTPM]":"80.3","Cell RNA - LHCN-M2 [nTPM]":"324.1","Cell RNA - MCF7 [nTPM]":"161.8","Cell RNA - MOLT-4 [nTPM]":"87.3","Cell RNA - NB-4 [nTPM]":"68.3","Cell RNA - NTERA-2 [nTPM]":"397.2","Cell RNA - OE19 [nTPM]":"211.0","Cell RNA - PC-3 [nTPM]":"159.3","Cell RNA - REH [nTPM]":"64.9","Cell RNA - RH-30 [nTPM]":"281.9","Cell RNA - RPMI-8226 [nTPM]":"88.3","Cell RNA - RPTEC TERT1 [nTPM]":"177.9","Cell RNA - RT4 [nTPM]":"494.8","Cell RNA - SCLC-21H [nTPM]":"102.9","Cell RNA - SH-SY5Y [nTPM]":"172.4","Cell RNA - SiHa [nTPM]":"296.2","Cell RNA - SK-BR-3 [nTPM]":"147.1","Cell RNA - SK-MEL-30 [nTPM]":"809.4","Cell RNA - SuSa [nTPM]":"509.8","Cell RNA - T-47d [nTPM]":"242.1","Cell RNA - THP-1 [nTPM]":"248.6","Cell RNA - TIME [nTPM]":"340.8","Cell RNA - U-138 MG [nTPM]":"217.1","Cell RNA - U-2 OS [nTPM]":"163.6","Cell RNA - U-2197 [nTPM]":"139.3","Cell RNA - U-251 MG [nTPM]":"264.0","Cell RNA - U-266\/70 [nTPM]":"50.7","Cell RNA - U-266\/84 [nTPM]":"82.7","Cell RNA - U-698 [nTPM]":"138.4","Cell RNA - U-87 MG [nTPM]":"221.5","Cell RNA - U-937 [nTPM]":"150.5","Cell RNA - WM-115 [nTPM]":"369.7","Blood RNA - basophil [nTPM]":"4.7","Blood RNA - classical monocyte [nTPM]":"7.3","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"9.2","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"10.9","Blood RNA - memory B-cell [nTPM]":"7.7","Blood RNA - memory CD4 T-cell [nTPM]":"8.6","Blood RNA - memory CD8 T-cell [nTPM]":"10.1","Blood RNA - myeloid DC [nTPM]":"11.8","Blood RNA - naive B-cell [nTPM]":"8.0","Blood RNA - naive CD4 T-cell [nTPM]":"8.6","Blood RNA - naive CD8 T-cell [nTPM]":"9.4","Blood RNA - neutrophil [nTPM]":"6.6","Blood RNA - NK-cell [nTPM]":"9.6","Blood RNA - non-classical monocyte [nTPM]":"12.6","Blood RNA - plasmacytoid DC [nTPM]":"10.0","Blood RNA - T-reg [nTPM]":"10.8","Blood RNA - total PBMC [nTPM]":"5.6","Brain RNA - amygdala [nTPM]":"106.7","Brain RNA - basal ganglia [nTPM]":"85.3","Brain RNA - cerebellum [nTPM]":"147.8","Brain RNA - cerebral cortex [nTPM]":"87.5","Brain RNA - hippocampal formation [nTPM]":"88.1","Brain RNA - hypothalamus [nTPM]":"105.3","Brain RNA - medulla oblongata [nTPM]":"101.3","Brain RNA - midbrain [nTPM]":"112.9","Brain RNA - pons [nTPM]":"94.0","Brain RNA - spinal cord [nTPM]":"104.9","Brain RNA - thalamus [nTPM]":"129.4","Brain RNA - white matter [nTPM]":"108.4","Single Cell Type RNA - Adipocytes [nTPM]":"171.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"137.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"179.5","Single Cell Type RNA - Astrocytes [nTPM]":"58.1","Single Cell Type RNA - B-cells [nTPM]":"71.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"213.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"130.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"75.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"116.1","Single Cell Type RNA - Bipolar cells [nTPM]":"40.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"232.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"168.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"84.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"90.1","Single Cell Type RNA - Club cells [nTPM]":"119.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"318.9","Single Cell Type RNA - dendritic cells [nTPM]":"99.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"251.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"35.2","Single Cell Type RNA - Ductal cells [nTPM]":"132.2","Single Cell Type RNA - Early spermatids [nTPM]":"11.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"90.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"125.9","Single Cell Type RNA - Endothelial cells [nTPM]":"187.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"93.8","Single Cell Type RNA - Erythroid cells [nTPM]":"43.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"78.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"115.6","Single Cell Type RNA - Fibroblasts [nTPM]":"116.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"95.5","Single Cell Type RNA - granulocytes [nTPM]":"116.6","Single Cell Type RNA - Granulosa cells [nTPM]":"137.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"139.2","Single Cell Type RNA - Hepatocytes [nTPM]":"172.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"115.1","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"82.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"145.9","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"154.6","Single Cell Type RNA - Langerhans cells [nTPM]":"228.1","Single Cell Type RNA - Late spermatids [nTPM]":"9.5","Single Cell Type RNA - Leydig cells [nTPM]":"59.7","Single Cell Type RNA - Macrophages [nTPM]":"161.1","Single Cell Type RNA - Melanocytes [nTPM]":"202.7","Single Cell Type RNA - Microglial cells [nTPM]":"124.6","Single Cell Type RNA - monocytes [nTPM]":"98.3","Single Cell Type RNA - Muller glia cells [nTPM]":"89.2","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"70.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"139.8","Single Cell Type RNA - Paneth cells [nTPM]":"249.5","Single Cell Type RNA - Peritubular cells [nTPM]":"86.9","Single Cell Type RNA - Plasma cells [nTPM]":"55.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"128.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"160.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"93.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"96.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.0","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"175.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"137.3","Single Cell Type RNA - Spermatocytes [nTPM]":"78.4","Single Cell Type RNA - Spermatogonia [nTPM]":"40.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"70.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"174.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"539.5","Single Cell Type RNA - T-cells [nTPM]":"77.0","Single Cell Type RNA - Theca cells [nTPM]":"245.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"189.6","Single Cell Type RNA - Urothelial cells [nTPM]":"127.9"},{"Gene":"DAPK1","Gene synonym":["DAPK","ROCO3"],"Ensembl":"ENSG00000196730","Gene description":"Death associated protein kinase 1","Uniprot":["P53355"],"Chromosome":"9","Position":"87497228-87708634","Protein class":["Cancer-related genes","Enzymes","Human disease related genes","Metabolic proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Translation regulation"],"Molecular function":["Calmodulin-binding","Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"139.1","Excitatory neurons":"120.2","Inhibitory neurons":"155.9","Kupffer cells":"85.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"classical monocyte":"6.7","eosinophil":"8.7","intermediate monocyte":"14.0","myeloid DC":"4.8","non-classical monocyte":"15.2","plasmacytoid DC":"6.2"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"56","RNA blood lineage specific nTPM":{"dendritic cells":"6.2","granulocytes":"8.7","monocytes":"15.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"97.6","HUVEC TERT2":"56.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB037302","HPA040472","HPA048436"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 29: Non-specific - Vesicular transport","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Centrosome"],"Subcellular additional location":null,"Antibody RRID":{"CAB037302":"AB_1078622","HPA040472":"AB_2677001","HPA048436":"AB_2680390"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.77e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Tissue RNA - adipose tissue [nTPM]":"22.9","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"12.1","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"16.4","Tissue RNA - bone marrow [nTPM]":"5.4","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"20.5","Tissue RNA - cervix [nTPM]":"9.6","Tissue RNA - choroid plexus [nTPM]":"12.6","Tissue RNA - colon [nTPM]":"27.1","Tissue RNA - duodenum [nTPM]":"10.1","Tissue RNA - endometrium 1 [nTPM]":"7.9","Tissue RNA - epididymis [nTPM]":"18.8","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"15.2","Tissue RNA - gallbladder [nTPM]":"28.0","Tissue RNA - heart muscle [nTPM]":"5.2","Tissue RNA - hippocampal formation [nTPM]":"22.8","Tissue RNA - hypothalamus [nTPM]":"7.6","Tissue RNA - kidney [nTPM]":"22.0","Tissue RNA - liver [nTPM]":"27.6","Tissue RNA - lung [nTPM]":"37.5","Tissue RNA - lymph node [nTPM]":"12.5","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"46.0","Tissue RNA - pancreas [nTPM]":"29.2","Tissue RNA - parathyroid gland [nTPM]":"6.7","Tissue RNA - pituitary gland [nTPM]":"23.4","Tissue RNA - placenta [nTPM]":"27.3","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"11.5","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"8.5","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"14.4","Tissue RNA - smooth muscle [nTPM]":"9.4","Tissue RNA - spinal cord [nTPM]":"7.8","Tissue RNA - spleen [nTPM]":"22.8","Tissue RNA - stomach 1 [nTPM]":"19.5","Tissue RNA - testis [nTPM]":"8.1","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"41.8","Tissue RNA - thyroid gland [nTPM]":"9.8","Tissue RNA - tongue [nTPM]":"2.3","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"14.5","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"7.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"47.5","Cell RNA - AF22 [nTPM]":"22.5","Cell RNA - AN3-CA [nTPM]":"15.8","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"4.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.4","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"0.3","Cell RNA - Daudi [nTPM]":"0.4","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"1.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"43.9","Cell RNA - HAP1 [nTPM]":"13.9","Cell RNA - HBEC3-KT [nTPM]":"1.0","Cell RNA - HBF TERT88 [nTPM]":"7.9","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"11.4","Cell RNA - HEL [nTPM]":"23.4","Cell RNA - HeLa [nTPM]":"6.6","Cell RNA - Hep G2 [nTPM]":"23.7","Cell RNA - HHSteC [nTPM]":"19.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"97.6","Cell RNA - HSkMC [nTPM]":"1.4","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.5","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"28.5","Cell RNA - HUVEC TERT2 [nTPM]":"56.3","Cell RNA - JURKAT [nTPM]":"6.5","Cell RNA - K-562 [nTPM]":"17.8","Cell RNA - Karpas-707 [nTPM]":"9.6","Cell RNA - LHCN-M2 [nTPM]":"15.4","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"7.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"25.4","Cell RNA - OE19 [nTPM]":"44.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"2.0","Cell RNA - RH-30 [nTPM]":"19.8","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"50.6","Cell RNA - RT4 [nTPM]":"47.6","Cell RNA - SCLC-21H [nTPM]":"10.2","Cell RNA - SH-SY5Y [nTPM]":"11.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"4.6","Cell RNA - SK-MEL-30 [nTPM]":"20.1","Cell RNA - SuSa [nTPM]":"32.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"15.2","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"36.9","Cell RNA - U-266\/84 [nTPM]":"8.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"6.4","Cell RNA - WM-115 [nTPM]":"3.0","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"6.7","Blood RNA - eosinophil [nTPM]":"8.7","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"14.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"2.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"15.2","Blood RNA - plasmacytoid DC [nTPM]":"6.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"3.0","Brain RNA - amygdala [nTPM]":"12.1","Brain RNA - basal ganglia [nTPM]":"16.4","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"20.5","Brain RNA - hippocampal formation [nTPM]":"22.8","Brain RNA - hypothalamus [nTPM]":"7.6","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"7.8","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"7.5","Single Cell Type RNA - Adipocytes [nTPM]":"8.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"72.2","Single Cell Type RNA - Astrocytes [nTPM]":"139.1","Single Cell Type RNA - B-cells [nTPM]":"2.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"19.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"31.5","Single Cell Type RNA - Club cells [nTPM]":"24.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"9.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"17.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"120.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.0","Single Cell Type RNA - Fibroblasts [nTPM]":"12.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"58.6","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"22.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.9","Single Cell Type RNA - Hepatocytes [nTPM]":"20.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.7","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"155.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"85.7","Single Cell Type RNA - Langerhans cells [nTPM]":"18.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"14.9","Single Cell Type RNA - Macrophages [nTPM]":"57.1","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"41.2","Single Cell Type RNA - Muller glia cells [nTPM]":"14.6","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.8","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"6.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"10.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.4","Single Cell Type RNA - Spermatogonia [nTPM]":"7.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.2","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"3.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"14.9"},{"Gene":"DAXX","Gene synonym":["DAP6"],"Ensembl":"ENSG00000204209","Gene description":"Death domain associated protein","Uniprot":["Q9UER7"],"Chromosome":"6","Position":"33318558-33323016","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chaperone","Chromatin regulator","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Rod photoreceptor cells":"111.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002224","HPA008736","HPA008797","CAB025546","HPA065779"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB002224":"AB_563688","CAB025546":null,"HPA008736":"AB_1078625","HPA008797":"AB_2797218","HPA065779":"AB_2685558"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.90e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.66e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.58e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.32e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Tissue RNA - adipose tissue [nTPM]":"27.5","Tissue RNA - adrenal gland [nTPM]":"33.6","Tissue RNA - amygdala [nTPM]":"6.4","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"6.2","Tissue RNA - bone marrow [nTPM]":"8.1","Tissue RNA - breast [nTPM]":"25.3","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"28.4","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"27.9","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"27.8","Tissue RNA - epididymis [nTPM]":"18.9","Tissue RNA - esophagus [nTPM]":"30.8","Tissue RNA - fallopian tube [nTPM]":"28.6","Tissue RNA - gallbladder [nTPM]":"7.2","Tissue RNA - heart muscle [nTPM]":"22.3","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"5.8","Tissue RNA - kidney [nTPM]":"23.2","Tissue RNA - liver [nTPM]":"25.0","Tissue RNA - lung [nTPM]":"24.0","Tissue RNA - lymph node [nTPM]":"8.7","Tissue RNA - medulla oblongata [nTPM]":"6.9","Tissue RNA - midbrain [nTPM]":"5.9","Tissue RNA - ovary [nTPM]":"23.8","Tissue RNA - pancreas [nTPM]":"23.1","Tissue RNA - parathyroid gland [nTPM]":"19.3","Tissue RNA - pituitary gland [nTPM]":"22.1","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"25.1","Tissue RNA - rectum [nTPM]":"10.8","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"24.2","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"35.4","Tissue RNA - skin 1 [nTPM]":"28.8","Tissue RNA - small intestine [nTPM]":"30.4","Tissue RNA - smooth muscle [nTPM]":"10.6","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"44.3","Tissue RNA - stomach 1 [nTPM]":"25.0","Tissue RNA - testis [nTPM]":"36.7","Tissue RNA - thalamus [nTPM]":"6.7","Tissue RNA - thymus [nTPM]":"23.5","Tissue RNA - thyroid gland [nTPM]":"24.2","Tissue RNA - tongue [nTPM]":"12.5","Tissue RNA - tonsil [nTPM]":"27.3","Tissue RNA - urinary bladder [nTPM]":"27.2","Tissue RNA - vagina [nTPM]":"25.9","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"20.8","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"38.0","Cell RNA - AN3-CA [nTPM]":"15.6","Cell RNA - ASC diff [nTPM]":"16.0","Cell RNA - ASC TERT1 [nTPM]":"16.0","Cell RNA - BEWO [nTPM]":"30.1","Cell RNA - BJ [nTPM]":"27.4","Cell RNA - BJ hTERT+ [nTPM]":"76.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"61.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"43.6","Cell RNA - CACO-2 [nTPM]":"1.6","Cell RNA - CAPAN-2 [nTPM]":"11.8","Cell RNA - Daudi [nTPM]":"58.5","Cell RNA - EFO-21 [nTPM]":"14.8","Cell RNA - fHDF\/TERT166 [nTPM]":"33.3","Cell RNA - GAMG [nTPM]":"65.5","Cell RNA - HaCaT [nTPM]":"11.8","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"46.1","Cell RNA - HBF TERT88 [nTPM]":"62.5","Cell RNA - HDLM-2 [nTPM]":"29.9","Cell RNA - HEK 293 [nTPM]":"39.6","Cell RNA - HEL [nTPM]":"52.0","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"39.9","Cell RNA - HHSteC [nTPM]":"26.5","Cell RNA - HL-60 [nTPM]":"37.0","Cell RNA - HMC-1 [nTPM]":"17.0","Cell RNA - HSkMC [nTPM]":"27.0","Cell RNA - hTCEpi [nTPM]":"32.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"25.8","Cell RNA - hTERT-HME1 [nTPM]":"31.0","Cell RNA - hTERT-RPE1 [nTPM]":"22.7","Cell RNA - HUVEC TERT2 [nTPM]":"15.5","Cell RNA - JURKAT [nTPM]":"16.2","Cell RNA - K-562 [nTPM]":"39.1","Cell RNA - Karpas-707 [nTPM]":"21.2","Cell RNA - LHCN-M2 [nTPM]":"32.1","Cell RNA - MCF7 [nTPM]":"23.2","Cell RNA - MOLT-4 [nTPM]":"29.7","Cell RNA - NB-4 [nTPM]":"54.1","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"9.1","Cell RNA - REH [nTPM]":"35.2","Cell RNA - RH-30 [nTPM]":"5.6","Cell RNA - RPMI-8226 [nTPM]":"41.8","Cell RNA - RPTEC TERT1 [nTPM]":"11.7","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"49.7","Cell RNA - SH-SY5Y [nTPM]":"20.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"22.7","Cell RNA - SuSa [nTPM]":"14.8","Cell RNA - T-47d [nTPM]":"17.5","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"22.9","Cell RNA - U-138 MG [nTPM]":"26.3","Cell RNA - U-2 OS [nTPM]":"29.1","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"35.4","Cell RNA - U-266\/84 [nTPM]":"58.3","Cell RNA - U-698 [nTPM]":"66.4","Cell RNA - U-87 MG [nTPM]":"23.3","Cell RNA - U-937 [nTPM]":"23.0","Cell RNA - WM-115 [nTPM]":"27.7","Blood RNA - basophil [nTPM]":"24.1","Blood RNA - classical monocyte [nTPM]":"22.5","Blood RNA - eosinophil [nTPM]":"47.3","Blood RNA - gdT-cell [nTPM]":"55.6","Blood RNA - intermediate monocyte [nTPM]":"28.9","Blood RNA - MAIT T-cell [nTPM]":"54.9","Blood RNA - memory B-cell [nTPM]":"58.8","Blood RNA - memory CD4 T-cell [nTPM]":"48.3","Blood RNA - memory CD8 T-cell [nTPM]":"61.3","Blood RNA - myeloid DC [nTPM]":"28.2","Blood RNA - naive B-cell [nTPM]":"56.8","Blood RNA - naive CD4 T-cell [nTPM]":"44.5","Blood RNA - naive CD8 T-cell [nTPM]":"49.6","Blood RNA - neutrophil [nTPM]":"22.9","Blood RNA - NK-cell [nTPM]":"62.9","Blood RNA - non-classical monocyte [nTPM]":"35.1","Blood RNA - plasmacytoid DC [nTPM]":"27.0","Blood RNA - T-reg [nTPM]":"59.0","Blood RNA - total PBMC [nTPM]":"70.5","Brain RNA - amygdala [nTPM]":"6.4","Brain RNA - basal ganglia [nTPM]":"6.2","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"5.8","Brain RNA - medulla oblongata [nTPM]":"6.9","Brain RNA - midbrain [nTPM]":"5.9","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"6.7","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"18.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"22.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.2","Single Cell Type RNA - B-cells [nTPM]":"45.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"58.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"36.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"48.3","Single Cell Type RNA - Bipolar cells [nTPM]":"19.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"25.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"27.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - dendritic cells [nTPM]":"41.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"38.5","Single Cell Type RNA - Early spermatids [nTPM]":"15.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.8","Single Cell Type RNA - Endothelial cells [nTPM]":"23.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"35.9","Single Cell Type RNA - Fibroblasts [nTPM]":"25.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"16.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"23.6","Single Cell Type RNA - granulocytes [nTPM]":"37.9","Single Cell Type RNA - Granulosa cells [nTPM]":"12.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.4","Single Cell Type RNA - Hepatocytes [nTPM]":"14.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.3","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"17.2","Single Cell Type RNA - Langerhans cells [nTPM]":"42.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.7","Single Cell Type RNA - Macrophages [nTPM]":"19.7","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"48.8","Single Cell Type RNA - Muller glia cells [nTPM]":"29.9","Single Cell Type RNA - NK-cells [nTPM]":"52.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"45.4","Single Cell Type RNA - Paneth cells [nTPM]":"21.8","Single Cell Type RNA - Peritubular cells [nTPM]":"23.3","Single Cell Type RNA - Plasma cells [nTPM]":"38.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.9","Single Cell Type RNA - Spermatocytes [nTPM]":"63.8","Single Cell Type RNA - Spermatogonia [nTPM]":"41.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - T-cells [nTPM]":"42.8","Single Cell Type RNA - Theca cells [nTPM]":"24.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.0","Single Cell Type RNA - Urothelial cells [nTPM]":"35.7"},{"Gene":"DCC","Gene synonym":["IGDCC1","NTN1R1"],"Ensembl":"ENSG00000187323","Gene description":"DCC netrin 1 receptor","Uniprot":["P43146"],"Chromosome":"18","Position":"52340197-53535903","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"brain":"6.9","testis":"7.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"205.7","Excitatory neurons":"439.7","Inhibitory neurons":"455.8","Late spermatids":"174.9","Oligodendrocyte precursor cells":"1305.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"0.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"AF22":"36.4","U-266\/70":"112.5","U-266\/84":"57.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA055376","HPA069552"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"64000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA055376":"AB_2682798","HPA069552":"AB_2686151"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.2","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"0.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.3","Tissue RNA - urinary bladder [nTPM]":"0.1","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"36.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"11.4","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"112.5","Cell RNA - U-266\/84 [nTPM]":"57.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"6.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.0","Single Cell Type RNA - Astrocytes [nTPM]":"10.1","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"205.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"439.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"455.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"174.9","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"54.4","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1305.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"58.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.6","Single Cell Type RNA - Spermatogonia [nTPM]":"1.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"DDIT3","Gene synonym":["CHOP","CHOP10","GADD153"],"Ensembl":"ENSG00000175197","Gene description":"DNA damage inducible transcript 3","Uniprot":["P35638"],"Chromosome":"12","Position":"57516588-57521737","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Apoptosis","Cell cycle","Growth arrest","Stress response","Transcription","Transcription regulation","Unfolded protein response","Wnt signaling pathway"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"170.7"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HHSteC":"784.2","hTERT-HME1":"399.9","SK-MEL-30":"409.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA058416","HPA068416"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA058416":"AB_2683712","HPA068416":"AB_2685985"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.55e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Tissue RNA - adipose tissue [nTPM]":"65.3","Tissue RNA - adrenal gland [nTPM]":"66.2","Tissue RNA - amygdala [nTPM]":"90.6","Tissue RNA - appendix [nTPM]":"16.1","Tissue RNA - basal ganglia [nTPM]":"97.8","Tissue RNA - bone marrow [nTPM]":"196.5","Tissue RNA - breast [nTPM]":"64.3","Tissue RNA - cerebellum [nTPM]":"97.4","Tissue RNA - cerebral cortex [nTPM]":"145.5","Tissue RNA - cervix [nTPM]":"51.0","Tissue RNA - choroid plexus [nTPM]":"92.9","Tissue RNA - colon [nTPM]":"52.0","Tissue RNA - duodenum [nTPM]":"20.7","Tissue RNA - endometrium 1 [nTPM]":"39.1","Tissue RNA - epididymis [nTPM]":"109.3","Tissue RNA - esophagus [nTPM]":"31.6","Tissue RNA - fallopian tube [nTPM]":"41.2","Tissue RNA - gallbladder [nTPM]":"32.1","Tissue RNA - heart muscle [nTPM]":"85.1","Tissue RNA - hippocampal formation [nTPM]":"89.0","Tissue RNA - hypothalamus [nTPM]":"99.2","Tissue RNA - kidney [nTPM]":"106.4","Tissue RNA - liver [nTPM]":"81.7","Tissue RNA - lung [nTPM]":"55.4","Tissue RNA - lymph node [nTPM]":"18.8","Tissue RNA - medulla oblongata [nTPM]":"95.9","Tissue RNA - midbrain [nTPM]":"98.4","Tissue RNA - ovary [nTPM]":"57.4","Tissue RNA - pancreas [nTPM]":"37.3","Tissue RNA - parathyroid gland [nTPM]":"80.5","Tissue RNA - pituitary gland [nTPM]":"81.4","Tissue RNA - placenta [nTPM]":"37.6","Tissue RNA - pons [nTPM]":"97.1","Tissue RNA - prostate [nTPM]":"45.5","Tissue RNA - rectum [nTPM]":"26.6","Tissue RNA - retina [nTPM]":"123.1","Tissue RNA - salivary gland [nTPM]":"43.3","Tissue RNA - seminal vesicle [nTPM]":"25.8","Tissue RNA - skeletal muscle [nTPM]":"44.8","Tissue RNA - skin 1 [nTPM]":"48.7","Tissue RNA - small intestine [nTPM]":"28.0","Tissue RNA - smooth muscle [nTPM]":"29.2","Tissue RNA - spinal cord [nTPM]":"95.5","Tissue RNA - spleen [nTPM]":"34.2","Tissue RNA - stomach 1 [nTPM]":"44.4","Tissue RNA - testis [nTPM]":"40.9","Tissue RNA - thalamus [nTPM]":"106.4","Tissue RNA - thymus [nTPM]":"17.8","Tissue RNA - thyroid gland [nTPM]":"182.1","Tissue RNA - tongue [nTPM]":"55.4","Tissue RNA - tonsil [nTPM]":"17.5","Tissue RNA - urinary bladder [nTPM]":"56.2","Tissue RNA - vagina [nTPM]":"49.5","Tissue RNA - white matter [nTPM]":"129.5","Cell RNA - A-431 [nTPM]":"17.8","Cell RNA - A549 [nTPM]":"16.1","Cell RNA - AF22 [nTPM]":"10.1","Cell RNA - AN3-CA [nTPM]":"34.5","Cell RNA - ASC diff [nTPM]":"90.7","Cell RNA - ASC TERT1 [nTPM]":"61.0","Cell RNA - BEWO [nTPM]":"53.8","Cell RNA - BJ [nTPM]":"48.2","Cell RNA - BJ hTERT+ [nTPM]":"106.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"70.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"65.4","Cell RNA - CACO-2 [nTPM]":"57.2","Cell RNA - CAPAN-2 [nTPM]":"45.7","Cell RNA - Daudi [nTPM]":"25.3","Cell RNA - EFO-21 [nTPM]":"46.9","Cell RNA - fHDF\/TERT166 [nTPM]":"14.3","Cell RNA - GAMG [nTPM]":"186.7","Cell RNA - HaCaT [nTPM]":"21.4","Cell RNA - HAP1 [nTPM]":"38.5","Cell RNA - HBEC3-KT [nTPM]":"7.3","Cell RNA - HBF TERT88 [nTPM]":"72.2","Cell RNA - HDLM-2 [nTPM]":"21.0","Cell RNA - HEK 293 [nTPM]":"15.5","Cell RNA - HEL [nTPM]":"19.9","Cell RNA - HeLa [nTPM]":"19.9","Cell RNA - Hep G2 [nTPM]":"42.3","Cell RNA - HHSteC [nTPM]":"784.2","Cell RNA - HL-60 [nTPM]":"31.8","Cell RNA - HMC-1 [nTPM]":"29.3","Cell RNA - HSkMC [nTPM]":"175.7","Cell RNA - hTCEpi [nTPM]":"152.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"118.6","Cell RNA - hTERT-HME1 [nTPM]":"399.9","Cell RNA - hTERT-RPE1 [nTPM]":"81.7","Cell RNA - HUVEC TERT2 [nTPM]":"16.9","Cell RNA - JURKAT [nTPM]":"26.5","Cell RNA - K-562 [nTPM]":"86.4","Cell RNA - Karpas-707 [nTPM]":"94.0","Cell RNA - LHCN-M2 [nTPM]":"31.2","Cell RNA - MCF7 [nTPM]":"10.8","Cell RNA - MOLT-4 [nTPM]":"21.1","Cell RNA - NB-4 [nTPM]":"41.5","Cell RNA - NTERA-2 [nTPM]":"19.7","Cell RNA - OE19 [nTPM]":"37.3","Cell RNA - PC-3 [nTPM]":"37.5","Cell RNA - REH [nTPM]":"11.8","Cell RNA - RH-30 [nTPM]":"220.7","Cell RNA - RPMI-8226 [nTPM]":"22.3","Cell RNA - RPTEC TERT1 [nTPM]":"25.0","Cell RNA - RT4 [nTPM]":"22.3","Cell RNA - SCLC-21H [nTPM]":"20.9","Cell RNA - SH-SY5Y [nTPM]":"15.3","Cell RNA - SiHa [nTPM]":"14.2","Cell RNA - SK-BR-3 [nTPM]":"16.2","Cell RNA - SK-MEL-30 [nTPM]":"409.0","Cell RNA - SuSa [nTPM]":"37.2","Cell RNA - T-47d [nTPM]":"34.4","Cell RNA - THP-1 [nTPM]":"82.8","Cell RNA - TIME [nTPM]":"9.9","Cell RNA - U-138 MG [nTPM]":"47.5","Cell RNA - U-2 OS [nTPM]":"20.2","Cell RNA - U-2197 [nTPM]":"45.4","Cell RNA - U-251 MG [nTPM]":"42.0","Cell RNA - U-266\/70 [nTPM]":"164.4","Cell RNA - U-266\/84 [nTPM]":"60.3","Cell RNA - U-698 [nTPM]":"26.8","Cell RNA - U-87 MG [nTPM]":"57.4","Cell RNA - U-937 [nTPM]":"29.1","Cell RNA - WM-115 [nTPM]":"85.8","Blood RNA - basophil [nTPM]":"121.1","Blood RNA - classical monocyte [nTPM]":"17.9","Blood RNA - eosinophil [nTPM]":"48.8","Blood RNA - gdT-cell [nTPM]":"25.1","Blood RNA - intermediate monocyte [nTPM]":"16.6","Blood RNA - MAIT T-cell [nTPM]":"22.7","Blood RNA - memory B-cell [nTPM]":"48.3","Blood RNA - memory CD4 T-cell [nTPM]":"17.9","Blood RNA - memory CD8 T-cell [nTPM]":"23.6","Blood RNA - myeloid DC [nTPM]":"12.8","Blood RNA - naive B-cell [nTPM]":"44.8","Blood RNA - naive CD4 T-cell [nTPM]":"34.1","Blood RNA - naive CD8 T-cell [nTPM]":"31.1","Blood RNA - neutrophil [nTPM]":"170.7","Blood RNA - NK-cell [nTPM]":"35.6","Blood RNA - non-classical monocyte [nTPM]":"19.4","Blood RNA - plasmacytoid DC [nTPM]":"15.9","Blood RNA - T-reg [nTPM]":"23.8","Blood RNA - total PBMC [nTPM]":"18.0","Brain RNA - amygdala [nTPM]":"90.6","Brain RNA - basal ganglia [nTPM]":"97.8","Brain RNA - cerebellum [nTPM]":"97.4","Brain RNA - cerebral cortex [nTPM]":"145.5","Brain RNA - hippocampal formation [nTPM]":"89.0","Brain RNA - hypothalamus [nTPM]":"99.2","Brain RNA - medulla oblongata [nTPM]":"95.9","Brain RNA - midbrain [nTPM]":"98.4","Brain RNA - pons [nTPM]":"97.1","Brain RNA - spinal cord [nTPM]":"95.5","Brain RNA - thalamus [nTPM]":"106.4","Brain RNA - white matter [nTPM]":"129.5","Single Cell Type RNA - Adipocytes [nTPM]":"237.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"55.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"96.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"176.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"93.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"177.0","Single Cell Type RNA - Bipolar cells [nTPM]":"114.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"86.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"265.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"177.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"37.1","Single Cell Type RNA - Club cells [nTPM]":"56.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.3","Single Cell Type RNA - dendritic cells [nTPM]":"101.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"265.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"115.4","Single Cell Type RNA - Ductal cells [nTPM]":"43.3","Single Cell Type RNA - Early spermatids [nTPM]":"9.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"111.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.4","Single Cell Type RNA - Endothelial cells [nTPM]":"62.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"230.7","Single Cell Type RNA - Erythroid cells [nTPM]":"12.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"16.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.5","Single Cell Type RNA - Fibroblasts [nTPM]":"115.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"74.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"82.4","Single Cell Type RNA - granulocytes [nTPM]":"204.0","Single Cell Type RNA - Granulosa cells [nTPM]":"26.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.5","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.7","Single Cell Type RNA - Horizontal cells [nTPM]":"55.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"218.4","Single Cell Type RNA - Ionocytes [nTPM]":"101.7","Single Cell Type RNA - Kupffer cells [nTPM]":"30.4","Single Cell Type RNA - Langerhans cells [nTPM]":"81.6","Single Cell Type RNA - Late spermatids [nTPM]":"6.3","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"81.5","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"8.2","Single Cell Type RNA - Muller glia cells [nTPM]":"156.1","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"23.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.0","Single Cell Type RNA - Paneth cells [nTPM]":"300.0","Single Cell Type RNA - Peritubular cells [nTPM]":"38.0","Single Cell Type RNA - Plasma cells [nTPM]":"43.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"115.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"61.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"61.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"38.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"160.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"122.2","Single Cell Type RNA - Spermatocytes [nTPM]":"77.7","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"91.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"45.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"107.8","Single Cell Type RNA - T-cells [nTPM]":"89.7","Single Cell Type RNA - Theca cells [nTPM]":"37.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"127.2","Single Cell Type RNA - Urothelial cells [nTPM]":"65.1"},{"Gene":"DNMT3A","Gene synonym":[],"Ensembl":"ENSG00000119772","Gene description":"DNA methyltransferase 3 alpha","Uniprot":["Q9Y6K1"],"Chromosome":"2","Position":"25227855-25342590","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"127.2","Horizontal cells":"95.9","Rod photoreceptor cells":"143.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"59.6","REH":"59.5","SH-SY5Y":"71.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009469","HPA026588"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009469":"AB_2093990","HPA026588":"AB_1847812"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.38e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.58e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.18e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.49e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"9.0","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"8.7","Tissue RNA - breast [nTPM]":"6.2","Tissue RNA - cerebellum [nTPM]":"9.3","Tissue RNA - cerebral cortex [nTPM]":"10.7","Tissue RNA - cervix [nTPM]":"9.1","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"6.7","Tissue RNA - endometrium 1 [nTPM]":"9.3","Tissue RNA - epididymis [nTPM]":"8.7","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"7.9","Tissue RNA - kidney [nTPM]":"11.3","Tissue RNA - liver [nTPM]":"5.3","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"11.1","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"7.6","Tissue RNA - ovary [nTPM]":"13.0","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"4.2","Tissue RNA - pituitary gland [nTPM]":"11.5","Tissue RNA - placenta [nTPM]":"15.7","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"6.6","Tissue RNA - retina [nTPM]":"15.4","Tissue RNA - salivary gland [nTPM]":"6.2","Tissue RNA - seminal vesicle [nTPM]":"5.9","Tissue RNA - skeletal muscle [nTPM]":"21.0","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"8.9","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"5.2","Tissue RNA - spleen [nTPM]":"13.4","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"5.2","Tissue RNA - thalamus [nTPM]":"9.4","Tissue RNA - thymus [nTPM]":"20.6","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"10.2","Tissue RNA - tonsil [nTPM]":"9.0","Tissue RNA - urinary bladder [nTPM]":"7.3","Tissue RNA - vagina [nTPM]":"6.2","Tissue RNA - white matter [nTPM]":"11.3","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"8.1","Cell RNA - AF22 [nTPM]":"34.6","Cell RNA - AN3-CA [nTPM]":"8.3","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"45.2","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.8","Cell RNA - CACO-2 [nTPM]":"21.1","Cell RNA - CAPAN-2 [nTPM]":"13.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"4.7","Cell RNA - GAMG [nTPM]":"3.5","Cell RNA - HaCaT [nTPM]":"2.2","Cell RNA - HAP1 [nTPM]":"3.8","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"2.8","Cell RNA - HDLM-2 [nTPM]":"5.7","Cell RNA - HEK 293 [nTPM]":"4.3","Cell RNA - HEL [nTPM]":"14.7","Cell RNA - HeLa [nTPM]":"12.8","Cell RNA - Hep G2 [nTPM]":"25.4","Cell RNA - HHSteC [nTPM]":"8.8","Cell RNA - HL-60 [nTPM]":"2.9","Cell RNA - HMC-1 [nTPM]":"7.6","Cell RNA - HSkMC [nTPM]":"8.2","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.0","Cell RNA - hTERT-HME1 [nTPM]":"2.2","Cell RNA - hTERT-RPE1 [nTPM]":"9.1","Cell RNA - HUVEC TERT2 [nTPM]":"19.5","Cell RNA - JURKAT [nTPM]":"34.0","Cell RNA - K-562 [nTPM]":"18.0","Cell RNA - Karpas-707 [nTPM]":"2.9","Cell RNA - LHCN-M2 [nTPM]":"3.5","Cell RNA - MCF7 [nTPM]":"20.6","Cell RNA - MOLT-4 [nTPM]":"33.7","Cell RNA - NB-4 [nTPM]":"36.5","Cell RNA - NTERA-2 [nTPM]":"59.6","Cell RNA - OE19 [nTPM]":"14.3","Cell RNA - PC-3 [nTPM]":"4.2","Cell RNA - REH [nTPM]":"59.5","Cell RNA - RH-30 [nTPM]":"32.5","Cell RNA - RPMI-8226 [nTPM]":"3.8","Cell RNA - RPTEC TERT1 [nTPM]":"2.9","Cell RNA - RT4 [nTPM]":"3.4","Cell RNA - SCLC-21H [nTPM]":"18.6","Cell RNA - SH-SY5Y [nTPM]":"71.5","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"19.6","Cell RNA - SK-MEL-30 [nTPM]":"6.2","Cell RNA - SuSa [nTPM]":"29.5","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"16.2","Cell RNA - TIME [nTPM]":"6.8","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"4.7","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"2.5","Cell RNA - U-266\/70 [nTPM]":"5.6","Cell RNA - U-266\/84 [nTPM]":"5.1","Cell RNA - U-698 [nTPM]":"19.6","Cell RNA - U-87 MG [nTPM]":"2.2","Cell RNA - U-937 [nTPM]":"8.4","Cell RNA - WM-115 [nTPM]":"5.5","Blood RNA - basophil [nTPM]":"2.8","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"2.7","Blood RNA - intermediate monocyte [nTPM]":"1.7","Blood RNA - MAIT T-cell [nTPM]":"4.0","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"1.3","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.9","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"5.5","Blood RNA - non-classical monocyte [nTPM]":"2.7","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"9.3","Brain RNA - cerebral cortex [nTPM]":"10.7","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"7.9","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"7.6","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"5.2","Brain RNA - thalamus [nTPM]":"9.4","Brain RNA - white matter [nTPM]":"11.3","Single Cell Type RNA - Adipocytes [nTPM]":"18.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.1","Single Cell Type RNA - Astrocytes [nTPM]":"28.1","Single Cell Type RNA - B-cells [nTPM]":"11.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"5.7","Single Cell Type RNA - Bipolar cells [nTPM]":"73.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"127.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"40.6","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"19.1","Single Cell Type RNA - Endothelial cells [nTPM]":"20.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"15.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"49.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.7","Single Cell Type RNA - Fibroblasts [nTPM]":"16.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.7","Single Cell Type RNA - granulocytes [nTPM]":"37.4","Single Cell Type RNA - Granulosa cells [nTPM]":"37.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"6.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.2","Single Cell Type RNA - Horizontal cells [nTPM]":"95.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"14.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"13.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"7.4","Single Cell Type RNA - Muller glia cells [nTPM]":"20.6","Single Cell Type RNA - NK-cells [nTPM]":"13.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"36.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"63.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"9.4","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"9.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"143.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"15.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.8","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.2","Single Cell Type RNA - T-cells [nTPM]":"19.6","Single Cell Type RNA - Theca cells [nTPM]":"26.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"10.2"},{"Gene":"DUSP22","Gene synonym":["JKAP","JSP1","MKPX","VHX"],"Ensembl":"ENSG00000112679","Gene description":"Dual specificity phosphatase 22","Uniprot":["Q9NRW4"],"Chromosome":"6","Position":"291630-351355","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"270.6","U-266\/70":"130.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031394"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA031394":"AB_10604114"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.34e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.70e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Tissue RNA - adipose tissue [nTPM]":"36.9","Tissue RNA - adrenal gland [nTPM]":"16.4","Tissue RNA - amygdala [nTPM]":"25.6","Tissue RNA - appendix [nTPM]":"27.7","Tissue RNA - basal ganglia [nTPM]":"29.1","Tissue RNA - bone marrow [nTPM]":"23.7","Tissue RNA - breast [nTPM]":"33.0","Tissue RNA - cerebellum [nTPM]":"27.4","Tissue RNA - cerebral cortex [nTPM]":"28.8","Tissue RNA - cervix [nTPM]":"31.6","Tissue RNA - choroid plexus [nTPM]":"21.2","Tissue RNA - colon [nTPM]":"47.8","Tissue RNA - duodenum [nTPM]":"22.5","Tissue RNA - endometrium 1 [nTPM]":"28.9","Tissue RNA - epididymis [nTPM]":"12.2","Tissue RNA - esophagus [nTPM]":"45.7","Tissue RNA - fallopian tube [nTPM]":"25.9","Tissue RNA - gallbladder [nTPM]":"21.3","Tissue RNA - heart muscle [nTPM]":"42.1","Tissue RNA - hippocampal formation [nTPM]":"25.1","Tissue RNA - hypothalamus [nTPM]":"27.1","Tissue RNA - kidney [nTPM]":"32.4","Tissue RNA - liver [nTPM]":"32.7","Tissue RNA - lung [nTPM]":"38.5","Tissue RNA - lymph node [nTPM]":"32.4","Tissue RNA - medulla oblongata [nTPM]":"32.3","Tissue RNA - midbrain [nTPM]":"28.5","Tissue RNA - ovary [nTPM]":"19.6","Tissue RNA - pancreas [nTPM]":"40.8","Tissue RNA - parathyroid gland [nTPM]":"13.2","Tissue RNA - pituitary gland [nTPM]":"21.2","Tissue RNA - placenta [nTPM]":"27.3","Tissue RNA - pons [nTPM]":"30.3","Tissue RNA - prostate [nTPM]":"23.2","Tissue RNA - rectum [nTPM]":"16.1","Tissue RNA - retina [nTPM]":"7.8","Tissue RNA - salivary gland [nTPM]":"30.4","Tissue RNA - seminal vesicle [nTPM]":"15.1","Tissue RNA - skeletal muscle [nTPM]":"52.3","Tissue RNA - skin 1 [nTPM]":"41.4","Tissue RNA - small intestine [nTPM]":"33.7","Tissue RNA - smooth muscle [nTPM]":"22.0","Tissue RNA - spinal cord [nTPM]":"28.0","Tissue RNA - spleen [nTPM]":"43.9","Tissue RNA - stomach 1 [nTPM]":"32.7","Tissue RNA - testis [nTPM]":"44.9","Tissue RNA - thalamus [nTPM]":"29.3","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"28.1","Tissue RNA - tongue [nTPM]":"37.7","Tissue RNA - tonsil [nTPM]":"30.5","Tissue RNA - urinary bladder [nTPM]":"30.3","Tissue RNA - vagina [nTPM]":"36.8","Tissue RNA - white matter [nTPM]":"42.7","Cell RNA - A-431 [nTPM]":"13.7","Cell RNA - A549 [nTPM]":"8.3","Cell RNA - AF22 [nTPM]":"17.3","Cell RNA - AN3-CA [nTPM]":"25.9","Cell RNA - ASC diff [nTPM]":"19.5","Cell RNA - ASC TERT1 [nTPM]":"21.5","Cell RNA - BEWO [nTPM]":"22.8","Cell RNA - BJ [nTPM]":"9.9","Cell RNA - BJ hTERT+ [nTPM]":"8.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.3","Cell RNA - CACO-2 [nTPM]":"8.8","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"28.4","Cell RNA - EFO-21 [nTPM]":"23.3","Cell RNA - fHDF\/TERT166 [nTPM]":"10.3","Cell RNA - GAMG [nTPM]":"18.3","Cell RNA - HaCaT [nTPM]":"9.4","Cell RNA - HAP1 [nTPM]":"21.9","Cell RNA - HBEC3-KT [nTPM]":"18.3","Cell RNA - HBF TERT88 [nTPM]":"6.1","Cell RNA - HDLM-2 [nTPM]":"68.6","Cell RNA - HEK 293 [nTPM]":"25.1","Cell RNA - HEL [nTPM]":"19.3","Cell RNA - HeLa [nTPM]":"7.1","Cell RNA - Hep G2 [nTPM]":"24.7","Cell RNA - HHSteC [nTPM]":"9.9","Cell RNA - HL-60 [nTPM]":"7.0","Cell RNA - HMC-1 [nTPM]":"24.4","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"54.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.2","Cell RNA - hTERT-HME1 [nTPM]":"11.3","Cell RNA - hTERT-RPE1 [nTPM]":"14.1","Cell RNA - HUVEC TERT2 [nTPM]":"24.8","Cell RNA - JURKAT [nTPM]":"24.0","Cell RNA - K-562 [nTPM]":"18.3","Cell RNA - Karpas-707 [nTPM]":"92.2","Cell RNA - LHCN-M2 [nTPM]":"7.2","Cell RNA - MCF7 [nTPM]":"8.2","Cell RNA - MOLT-4 [nTPM]":"10.3","Cell RNA - NB-4 [nTPM]":"25.1","Cell RNA - NTERA-2 [nTPM]":"10.4","Cell RNA - OE19 [nTPM]":"10.0","Cell RNA - PC-3 [nTPM]":"18.7","Cell RNA - REH [nTPM]":"20.2","Cell RNA - RH-30 [nTPM]":"11.7","Cell RNA - RPMI-8226 [nTPM]":"270.6","Cell RNA - RPTEC TERT1 [nTPM]":"16.2","Cell RNA - RT4 [nTPM]":"5.8","Cell RNA - SCLC-21H [nTPM]":"29.7","Cell RNA - SH-SY5Y [nTPM]":"11.6","Cell RNA - SiHa [nTPM]":"8.5","Cell RNA - SK-BR-3 [nTPM]":"3.4","Cell RNA - SK-MEL-30 [nTPM]":"29.6","Cell RNA - SuSa [nTPM]":"37.4","Cell RNA - T-47d [nTPM]":"17.6","Cell RNA - THP-1 [nTPM]":"8.9","Cell RNA - TIME [nTPM]":"34.2","Cell RNA - U-138 MG [nTPM]":"7.7","Cell RNA - U-2 OS [nTPM]":"10.1","Cell RNA - U-2197 [nTPM]":"7.8","Cell RNA - U-251 MG [nTPM]":"6.0","Cell RNA - U-266\/70 [nTPM]":"130.0","Cell RNA - U-266\/84 [nTPM]":"98.6","Cell RNA - U-698 [nTPM]":"40.0","Cell RNA - U-87 MG [nTPM]":"3.0","Cell RNA - U-937 [nTPM]":"19.0","Cell RNA - WM-115 [nTPM]":"17.7","Blood RNA - basophil [nTPM]":"36.4","Blood RNA - classical monocyte [nTPM]":"32.5","Blood RNA - eosinophil [nTPM]":"13.6","Blood RNA - gdT-cell [nTPM]":"8.6","Blood RNA - intermediate monocyte [nTPM]":"26.5","Blood RNA - MAIT T-cell [nTPM]":"6.2","Blood RNA - memory B-cell [nTPM]":"40.4","Blood RNA - memory CD4 T-cell [nTPM]":"6.7","Blood RNA - memory CD8 T-cell [nTPM]":"9.1","Blood RNA - myeloid DC [nTPM]":"33.5","Blood RNA - naive B-cell [nTPM]":"33.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.1","Blood RNA - naive CD8 T-cell [nTPM]":"8.8","Blood RNA - neutrophil [nTPM]":"21.8","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"25.1","Blood RNA - plasmacytoid DC [nTPM]":"28.8","Blood RNA - T-reg [nTPM]":"15.9","Blood RNA - total PBMC [nTPM]":"19.6","Brain RNA - amygdala [nTPM]":"25.6","Brain RNA - basal ganglia [nTPM]":"29.1","Brain RNA - cerebellum [nTPM]":"27.4","Brain RNA - cerebral cortex [nTPM]":"28.8","Brain RNA - hippocampal formation [nTPM]":"25.1","Brain RNA - hypothalamus [nTPM]":"27.1","Brain RNA - medulla oblongata [nTPM]":"32.3","Brain RNA - midbrain [nTPM]":"28.5","Brain RNA - pons [nTPM]":"30.3","Brain RNA - spinal cord [nTPM]":"28.0","Brain RNA - thalamus [nTPM]":"29.3","Brain RNA - white matter [nTPM]":"42.7","Single Cell Type RNA - Adipocytes [nTPM]":"45.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.3","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"53.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"33.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"40.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"30.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.8","Single Cell Type RNA - dendritic cells [nTPM]":"51.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"24.2","Single Cell Type RNA - Early spermatids [nTPM]":"13.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.2","Single Cell Type RNA - Endothelial cells [nTPM]":"33.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"21.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.9","Single Cell Type RNA - granulocytes [nTPM]":"33.0","Single Cell Type RNA - Granulosa cells [nTPM]":"8.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.8","Single Cell Type RNA - Hepatocytes [nTPM]":"25.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.7","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"38.6","Single Cell Type RNA - Langerhans cells [nTPM]":"43.0","Single Cell Type RNA - Late spermatids [nTPM]":"20.5","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"47.1","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"21.5","Single Cell Type RNA - monocytes [nTPM]":"78.4","Single Cell Type RNA - Muller glia cells [nTPM]":"14.9","Single Cell Type RNA - NK-cells [nTPM]":"36.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"25.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.2","Single Cell Type RNA - Paneth cells [nTPM]":"12.4","Single Cell Type RNA - Peritubular cells [nTPM]":"9.4","Single Cell Type RNA - Plasma cells [nTPM]":"59.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"39.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.2","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.8","Single Cell Type RNA - Spermatocytes [nTPM]":"34.5","Single Cell Type RNA - Spermatogonia [nTPM]":"73.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"37.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.6","Single Cell Type RNA - T-cells [nTPM]":"21.3","Single Cell Type RNA - Theca cells [nTPM]":"6.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.4","Single Cell Type RNA - Urothelial cells [nTPM]":"27.9"},{"Gene":"EDNRB","Gene synonym":["ETB","HSCR","HSCR2"],"Ensembl":"ENSG00000136160","Gene description":"Endothelin receptor type B","Uniprot":["P24530"],"Chromosome":"13","Position":"77895481-77975529","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Albinism","Deafness","Disease variant","FDA approved drug targets","Hirschsprung disease","Waardenburg syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"127.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"120.5","Astrocytes":"126.3","Hepatic stellate cells":"112.5","Melanocytes":"110.3","Muller glia cells":"116.2","Sertoli cells":"216.9","Skeletal myocytes":"81.3","Smooth muscle cells":"102.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"127.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"68.0","ASC diff":"50.5","SK-MEL-30":"66.0","U-266\/70":"40.7","WM-115":"131.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017842","HPA027546"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017842":null,"HPA027546":"AB_2672327"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.17e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.20e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-3"},"Tissue RNA - adipose tissue [nTPM]":"58.8","Tissue RNA - adrenal gland [nTPM]":"41.2","Tissue RNA - amygdala [nTPM]":"34.7","Tissue RNA - appendix [nTPM]":"19.5","Tissue RNA - basal ganglia [nTPM]":"50.8","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"39.8","Tissue RNA - cerebellum [nTPM]":"44.6","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"18.7","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"20.0","Tissue RNA - endometrium 1 [nTPM]":"13.1","Tissue RNA - epididymis [nTPM]":"3.7","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"14.9","Tissue RNA - heart muscle [nTPM]":"28.1","Tissue RNA - hippocampal formation [nTPM]":"27.5","Tissue RNA - hypothalamus [nTPM]":"51.6","Tissue RNA - kidney [nTPM]":"33.0","Tissue RNA - liver [nTPM]":"50.9","Tissue RNA - lung [nTPM]":"51.2","Tissue RNA - lymph node [nTPM]":"10.4","Tissue RNA - medulla oblongata [nTPM]":"76.2","Tissue RNA - midbrain [nTPM]":"66.0","Tissue RNA - ovary [nTPM]":"4.7","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"15.3","Tissue RNA - pituitary gland [nTPM]":"9.6","Tissue RNA - placenta [nTPM]":"127.8","Tissue RNA - pons [nTPM]":"47.9","Tissue RNA - prostate [nTPM]":"25.3","Tissue RNA - rectum [nTPM]":"13.2","Tissue RNA - retina [nTPM]":"17.9","Tissue RNA - salivary gland [nTPM]":"27.0","Tissue RNA - seminal vesicle [nTPM]":"6.9","Tissue RNA - skeletal muscle [nTPM]":"11.3","Tissue RNA - skin 1 [nTPM]":"12.5","Tissue RNA - small intestine [nTPM]":"21.9","Tissue RNA - smooth muscle [nTPM]":"12.9","Tissue RNA - spinal cord [nTPM]":"97.2","Tissue RNA - spleen [nTPM]":"16.8","Tissue RNA - stomach 1 [nTPM]":"10.6","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"64.9","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"31.8","Tissue RNA - tongue [nTPM]":"18.8","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"23.6","Tissue RNA - vagina [nTPM]":"15.5","Tissue RNA - white matter [nTPM]":"78.7","Cell RNA - A-431 [nTPM]":"5.7","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"68.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"50.5","Cell RNA - ASC TERT1 [nTPM]":"2.0","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"25.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.6","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.5","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"13.2","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"66.0","Cell RNA - SuSa [nTPM]":"8.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.6","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"40.7","Cell RNA - U-266\/84 [nTPM]":"24.9","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"131.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"34.7","Brain RNA - basal ganglia [nTPM]":"50.8","Brain RNA - cerebellum [nTPM]":"44.6","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"27.5","Brain RNA - hypothalamus [nTPM]":"51.6","Brain RNA - medulla oblongata [nTPM]":"76.2","Brain RNA - midbrain [nTPM]":"66.0","Brain RNA - pons [nTPM]":"47.9","Brain RNA - spinal cord [nTPM]":"97.2","Brain RNA - thalamus [nTPM]":"64.9","Brain RNA - white matter [nTPM]":"78.7","Single Cell Type RNA - Adipocytes [nTPM]":"120.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.0","Single Cell Type RNA - Astrocytes [nTPM]":"126.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.7","Single Cell Type RNA - Endothelial cells [nTPM]":"73.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.9","Single Cell Type RNA - Fibroblasts [nTPM]":"51.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.9","Single Cell Type RNA - granulocytes [nTPM]":"6.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"112.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"18.7","Single Cell Type RNA - Langerhans cells [nTPM]":"10.6","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"79.9","Single Cell Type RNA - Macrophages [nTPM]":"5.2","Single Cell Type RNA - Melanocytes [nTPM]":"110.3","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"116.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.4","Single Cell Type RNA - Sertoli cells [nTPM]":"216.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"102.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.7","Single Cell Type RNA - T-cells [nTPM]":"1.6","Single Cell Type RNA - Theca cells [nTPM]":"2.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"EGF","Gene synonym":[],"Ensembl":"ENSG00000138798","Gene description":"Epidermal growth factor","Uniprot":["P01133"],"Chromosome":"4","Position":"109912883-110013766","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Primary hypomagnesemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"kidney":"110.2","pancreas":"89.5","skeletal muscle":"29.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"12.9","Breast myoepithelial cells":"8.1","Cardiomyocytes":"8.2","Distal tubular cells":"7.9","Excitatory neurons":"8.5","Inhibitory neurons":"11.2","Muller glia cells":"26.2","Skeletal myocytes":"8.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"6.4","SK-BR-3":"11.6","U-251 MG":"3.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":209000,"Blood concentration - Conc. blood MS [pg\/L]":"680000","Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 37: Myocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.50e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-5"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.92e-3"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"1.0","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"2.4","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.3","Tissue RNA - gallbladder [nTPM]":"1.0","Tissue RNA - heart muscle [nTPM]":"2.8","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"110.2","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.4","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"89.5","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"0.4","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"13.6","Tissue RNA - salivary gland [nTPM]":"15.7","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"29.6","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.5","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"17.4","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"1.8","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"11.6","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"1.2","Cell RNA - T-47d [nTPM]":"2.8","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.9","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.1","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"1.4","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"1.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"3.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"8.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.3","Single Cell Type RNA - Muller glia cells [nTPM]":"26.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"EGFR","Gene synonym":["ERBB","ERBB1"],"Ensembl":"ENSG00000146648","Gene description":"Epidermal growth factor receptor","Uniprot":["P00533"],"Chromosome":"7","Position":"55019017-55211628","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Developmental protein","Host cell receptor for virus entry","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"287.9","Skeletal myocytes":"251.2","Syncytiotrophoblasts":"376.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"136.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"A-431":"5282.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000035","HPA001200","HPA018530","CAB068186","CAB073534"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4740000,"Blood concentration - Conc. blood MS [pg\/L]":"88000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB000035":null,"CAB068186":"AB_2665679","CAB073534":null,"HPA001200":"AB_1078723","HPA018530":"AB_1848044"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.04e-5"},"Tissue RNA - adipose tissue [nTPM]":"27.9","Tissue RNA - adrenal gland [nTPM]":"11.4","Tissue RNA - amygdala [nTPM]":"12.6","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"20.0","Tissue RNA - cerebellum [nTPM]":"16.6","Tissue RNA - cerebral cortex [nTPM]":"9.7","Tissue RNA - cervix [nTPM]":"20.4","Tissue RNA - choroid plexus [nTPM]":"10.5","Tissue RNA - colon [nTPM]":"12.2","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"11.4","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"23.5","Tissue RNA - fallopian tube [nTPM]":"13.9","Tissue RNA - gallbladder [nTPM]":"9.0","Tissue RNA - heart muscle [nTPM]":"7.1","Tissue RNA - hippocampal formation [nTPM]":"6.3","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"11.6","Tissue RNA - liver [nTPM]":"35.3","Tissue RNA - lung [nTPM]":"14.9","Tissue RNA - lymph node [nTPM]":"2.5","Tissue RNA - medulla oblongata [nTPM]":"10.4","Tissue RNA - midbrain [nTPM]":"19.0","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"15.8","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"67.9","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"22.1","Tissue RNA - seminal vesicle [nTPM]":"15.0","Tissue RNA - skeletal muscle [nTPM]":"10.9","Tissue RNA - skin 1 [nTPM]":"51.0","Tissue RNA - small intestine [nTPM]":"9.5","Tissue RNA - smooth muscle [nTPM]":"9.3","Tissue RNA - spinal cord [nTPM]":"7.5","Tissue RNA - spleen [nTPM]":"5.1","Tissue RNA - stomach 1 [nTPM]":"11.1","Tissue RNA - testis [nTPM]":"4.2","Tissue RNA - thalamus [nTPM]":"22.6","Tissue RNA - thymus [nTPM]":"12.8","Tissue RNA - thyroid gland [nTPM]":"20.6","Tissue RNA - tongue [nTPM]":"20.6","Tissue RNA - tonsil [nTPM]":"8.3","Tissue RNA - urinary bladder [nTPM]":"14.7","Tissue RNA - vagina [nTPM]":"24.1","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"5282.1","Cell RNA - A549 [nTPM]":"61.9","Cell RNA - AF22 [nTPM]":"16.5","Cell RNA - AN3-CA [nTPM]":"22.4","Cell RNA - ASC diff [nTPM]":"102.7","Cell RNA - ASC TERT1 [nTPM]":"63.5","Cell RNA - BEWO [nTPM]":"16.7","Cell RNA - BJ [nTPM]":"47.9","Cell RNA - BJ hTERT+ [nTPM]":"68.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"23.8","Cell RNA - CACO-2 [nTPM]":"11.5","Cell RNA - CAPAN-2 [nTPM]":"54.2","Cell RNA - Daudi [nTPM]":"2.7","Cell RNA - EFO-21 [nTPM]":"11.4","Cell RNA - fHDF\/TERT166 [nTPM]":"43.8","Cell RNA - GAMG [nTPM]":"130.7","Cell RNA - HaCaT [nTPM]":"197.1","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"230.2","Cell RNA - HBF TERT88 [nTPM]":"37.1","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"3.6","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"27.3","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"27.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"31.2","Cell RNA - hTCEpi [nTPM]":"205.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"74.1","Cell RNA - hTERT-HME1 [nTPM]":"409.9","Cell RNA - hTERT-RPE1 [nTPM]":"45.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"68.0","Cell RNA - MCF7 [nTPM]":"3.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"5.1","Cell RNA - OE19 [nTPM]":"21.2","Cell RNA - PC-3 [nTPM]":"30.4","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"9.1","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"38.1","Cell RNA - RT4 [nTPM]":"52.6","Cell RNA - SCLC-21H [nTPM]":"0.8","Cell RNA - SH-SY5Y [nTPM]":"20.0","Cell RNA - SiHa [nTPM]":"42.7","Cell RNA - SK-BR-3 [nTPM]":"50.6","Cell RNA - SK-MEL-30 [nTPM]":"9.3","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"4.9","Cell RNA - THP-1 [nTPM]":"12.0","Cell RNA - TIME [nTPM]":"15.6","Cell RNA - U-138 MG [nTPM]":"27.1","Cell RNA - U-2 OS [nTPM]":"7.2","Cell RNA - U-2197 [nTPM]":"215.7","Cell RNA - U-251 MG [nTPM]":"45.8","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"3.1","Cell RNA - U-87 MG [nTPM]":"37.9","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"8.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"12.6","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"16.6","Brain RNA - cerebral cortex [nTPM]":"9.7","Brain RNA - hippocampal formation [nTPM]":"6.3","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"10.4","Brain RNA - midbrain [nTPM]":"19.0","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"7.5","Brain RNA - thalamus [nTPM]":"22.6","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"16.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"96.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.9","Single Cell Type RNA - Astrocytes [nTPM]":"147.6","Single Cell Type RNA - B-cells [nTPM]":"1.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"85.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"77.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"101.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"116.1","Single Cell Type RNA - Bipolar cells [nTPM]":"3.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"50.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"287.9","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"45.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"32.9","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.2","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"37.1","Single Cell Type RNA - Fibroblasts [nTPM]":"91.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"22.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"50.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.8","Single Cell Type RNA - Hepatocytes [nTPM]":"79.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"107.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.6","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"7.7","Single Cell Type RNA - Langerhans cells [nTPM]":"11.6","Single Cell Type RNA - Late spermatids [nTPM]":"5.8","Single Cell Type RNA - Leydig cells [nTPM]":"128.3","Single Cell Type RNA - Macrophages [nTPM]":"1.9","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"90.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.8","Single Cell Type RNA - Paneth cells [nTPM]":"19.9","Single Cell Type RNA - Peritubular cells [nTPM]":"133.5","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"75.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.8","Single Cell Type RNA - Sertoli cells [nTPM]":"78.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"251.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.7","Single Cell Type RNA - Spermatocytes [nTPM]":"2.4","Single Cell Type RNA - Spermatogonia [nTPM]":"2.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"73.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"89.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"376.8","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"41.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.9","Single Cell Type RNA - Urothelial cells [nTPM]":"55.8"},{"Gene":"ELK4","Gene synonym":["SAP1"],"Ensembl":"ENSG00000158711","Gene description":"ETS transcription factor ELK4","Uniprot":["P28324"],"Chromosome":"1","Position":"205597556-205632011","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"104.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"6.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"6.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA028863"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA028863":"AB_10602492"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.65e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.94e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.58e-3"},"Tissue RNA - adipose tissue [nTPM]":"9.0","Tissue RNA - adrenal gland [nTPM]":"4.9","Tissue RNA - amygdala [nTPM]":"7.4","Tissue RNA - appendix [nTPM]":"11.5","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"11.7","Tissue RNA - breast [nTPM]":"8.1","Tissue RNA - cerebellum [nTPM]":"12.2","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"8.2","Tissue RNA - choroid plexus [nTPM]":"7.0","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"8.0","Tissue RNA - fallopian tube [nTPM]":"6.7","Tissue RNA - gallbladder [nTPM]":"9.2","Tissue RNA - heart muscle [nTPM]":"7.0","Tissue RNA - hippocampal formation [nTPM]":"6.0","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"13.2","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"8.8","Tissue RNA - ovary [nTPM]":"6.7","Tissue RNA - pancreas [nTPM]":"8.1","Tissue RNA - parathyroid gland [nTPM]":"7.8","Tissue RNA - pituitary gland [nTPM]":"5.5","Tissue RNA - placenta [nTPM]":"7.9","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"26.0","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"9.3","Tissue RNA - salivary gland [nTPM]":"8.2","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"10.6","Tissue RNA - skin 1 [nTPM]":"13.5","Tissue RNA - small intestine [nTPM]":"9.6","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"9.1","Tissue RNA - spleen [nTPM]":"15.8","Tissue RNA - stomach 1 [nTPM]":"7.7","Tissue RNA - testis [nTPM]":"7.3","Tissue RNA - thalamus [nTPM]":"8.5","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"8.7","Tissue RNA - tonsil [nTPM]":"16.8","Tissue RNA - urinary bladder [nTPM]":"9.6","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"14.1","Cell RNA - A-431 [nTPM]":"14.9","Cell RNA - A549 [nTPM]":"13.2","Cell RNA - AF22 [nTPM]":"5.1","Cell RNA - AN3-CA [nTPM]":"13.3","Cell RNA - ASC diff [nTPM]":"11.9","Cell RNA - ASC TERT1 [nTPM]":"15.2","Cell RNA - BEWO [nTPM]":"12.9","Cell RNA - BJ [nTPM]":"9.8","Cell RNA - BJ hTERT+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.9","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"14.6","Cell RNA - Daudi [nTPM]":"31.3","Cell RNA - EFO-21 [nTPM]":"9.0","Cell RNA - fHDF\/TERT166 [nTPM]":"12.2","Cell RNA - GAMG [nTPM]":"5.7","Cell RNA - HaCaT [nTPM]":"18.0","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"12.0","Cell RNA - HBF TERT88 [nTPM]":"13.1","Cell RNA - HDLM-2 [nTPM]":"35.9","Cell RNA - HEK 293 [nTPM]":"7.7","Cell RNA - HEL [nTPM]":"13.6","Cell RNA - HeLa [nTPM]":"22.0","Cell RNA - Hep G2 [nTPM]":"12.2","Cell RNA - HHSteC [nTPM]":"16.1","Cell RNA - HL-60 [nTPM]":"25.7","Cell RNA - HMC-1 [nTPM]":"51.8","Cell RNA - HSkMC [nTPM]":"13.4","Cell RNA - hTCEpi [nTPM]":"14.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.0","Cell RNA - hTERT-HME1 [nTPM]":"24.4","Cell RNA - hTERT-RPE1 [nTPM]":"14.7","Cell RNA - HUVEC TERT2 [nTPM]":"32.3","Cell RNA - JURKAT [nTPM]":"14.8","Cell RNA - K-562 [nTPM]":"12.7","Cell RNA - Karpas-707 [nTPM]":"25.6","Cell RNA - LHCN-M2 [nTPM]":"10.7","Cell RNA - MCF7 [nTPM]":"20.1","Cell RNA - MOLT-4 [nTPM]":"21.3","Cell RNA - NB-4 [nTPM]":"9.5","Cell RNA - NTERA-2 [nTPM]":"8.5","Cell RNA - OE19 [nTPM]":"3.4","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"31.2","Cell RNA - RPMI-8226 [nTPM]":"25.4","Cell RNA - RPTEC TERT1 [nTPM]":"10.2","Cell RNA - RT4 [nTPM]":"32.0","Cell RNA - SCLC-21H [nTPM]":"5.9","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"25.2","Cell RNA - SK-BR-3 [nTPM]":"13.7","Cell RNA - SK-MEL-30 [nTPM]":"17.3","Cell RNA - SuSa [nTPM]":"8.9","Cell RNA - T-47d [nTPM]":"12.7","Cell RNA - THP-1 [nTPM]":"8.5","Cell RNA - TIME [nTPM]":"23.5","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"17.8","Cell RNA - U-2197 [nTPM]":"13.7","Cell RNA - U-251 MG [nTPM]":"18.8","Cell RNA - U-266\/70 [nTPM]":"19.1","Cell RNA - U-266\/84 [nTPM]":"18.9","Cell RNA - U-698 [nTPM]":"21.1","Cell RNA - U-87 MG [nTPM]":"13.3","Cell RNA - U-937 [nTPM]":"10.3","Cell RNA - WM-115 [nTPM]":"18.2","Blood RNA - basophil [nTPM]":"6.6","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.1","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"7.4","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"12.2","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.0","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"8.8","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"9.1","Brain RNA - thalamus [nTPM]":"8.5","Brain RNA - white matter [nTPM]":"14.1","Single Cell Type RNA - Adipocytes [nTPM]":"50.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.2","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"39.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"35.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"104.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"34.3","Single Cell Type RNA - Club cells [nTPM]":"17.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.6","Single Cell Type RNA - dendritic cells [nTPM]":"34.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.7","Single Cell Type RNA - Early spermatids [nTPM]":"17.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.4","Single Cell Type RNA - Endothelial cells [nTPM]":"40.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"21.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"22.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"17.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"82.5","Single Cell Type RNA - granulocytes [nTPM]":"28.5","Single Cell Type RNA - Granulosa cells [nTPM]":"12.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"36.4","Single Cell Type RNA - Hepatocytes [nTPM]":"30.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"18.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.5","Single Cell Type RNA - Langerhans cells [nTPM]":"39.1","Single Cell Type RNA - Late spermatids [nTPM]":"19.5","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"22.3","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"22.3","Single Cell Type RNA - Muller glia cells [nTPM]":"11.2","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"28.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"18.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"71.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"26.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.4","Single Cell Type RNA - Spermatocytes [nTPM]":"24.6","Single Cell Type RNA - Spermatogonia [nTPM]":"11.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"48.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"18.3","Single Cell Type RNA - T-cells [nTPM]":"32.6","Single Cell Type RNA - Theca cells [nTPM]":"16.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.5","Single Cell Type RNA - Urothelial cells [nTPM]":"103.1"},{"Gene":"EP300","Gene synonym":["KAT3B","p300"],"Ensembl":"ENSG00000100393","Gene description":"E1A binding protein p300","Uniprot":["Q09472"],"Chromosome":"22","Position":"41092592-41180077","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000146","HPA003128","HPA004112"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000146":"AB_2533138","HPA003128":"AB_1078745","HPA004112":"AB_1078746"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.7","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"6.8","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"8.9","Tissue RNA - bone marrow [nTPM]":"65.1","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"10.8","Tissue RNA - cervix [nTPM]":"16.0","Tissue RNA - choroid plexus [nTPM]":"6.1","Tissue RNA - colon [nTPM]":"16.6","Tissue RNA - duodenum [nTPM]":"13.6","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"13.5","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"16.4","Tissue RNA - gallbladder [nTPM]":"14.2","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"9.4","Tissue RNA - kidney [nTPM]":"13.1","Tissue RNA - liver [nTPM]":"15.5","Tissue RNA - lung [nTPM]":"14.7","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"10.6","Tissue RNA - midbrain [nTPM]":"7.8","Tissue RNA - ovary [nTPM]":"23.9","Tissue RNA - pancreas [nTPM]":"18.0","Tissue RNA - parathyroid gland [nTPM]":"23.2","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"19.3","Tissue RNA - pons [nTPM]":"7.7","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"17.8","Tissue RNA - salivary gland [nTPM]":"15.0","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"20.4","Tissue RNA - skin 1 [nTPM]":"18.9","Tissue RNA - small intestine [nTPM]":"16.0","Tissue RNA - smooth muscle [nTPM]":"16.4","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"17.0","Tissue RNA - stomach 1 [nTPM]":"14.5","Tissue RNA - testis [nTPM]":"19.6","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"27.2","Tissue RNA - thyroid gland [nTPM]":"20.2","Tissue RNA - tongue [nTPM]":"23.4","Tissue RNA - tonsil [nTPM]":"17.9","Tissue RNA - urinary bladder [nTPM]":"15.4","Tissue RNA - vagina [nTPM]":"14.8","Tissue RNA - white matter [nTPM]":"11.2","Cell RNA - A-431 [nTPM]":"31.6","Cell RNA - A549 [nTPM]":"21.7","Cell RNA - AF22 [nTPM]":"35.4","Cell RNA - AN3-CA [nTPM]":"23.0","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"23.3","Cell RNA - BEWO [nTPM]":"32.3","Cell RNA - BJ [nTPM]":"15.0","Cell RNA - BJ hTERT+ [nTPM]":"21.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.0","Cell RNA - CACO-2 [nTPM]":"27.8","Cell RNA - CAPAN-2 [nTPM]":"12.0","Cell RNA - Daudi [nTPM]":"32.7","Cell RNA - EFO-21 [nTPM]":"12.2","Cell RNA - fHDF\/TERT166 [nTPM]":"28.4","Cell RNA - GAMG [nTPM]":"18.7","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"48.1","Cell RNA - HBEC3-KT [nTPM]":"20.8","Cell RNA - HBF TERT88 [nTPM]":"23.5","Cell RNA - HDLM-2 [nTPM]":"30.5","Cell RNA - HEK 293 [nTPM]":"32.2","Cell RNA - HEL [nTPM]":"24.4","Cell RNA - HeLa [nTPM]":"25.4","Cell RNA - Hep G2 [nTPM]":"22.3","Cell RNA - HHSteC [nTPM]":"26.9","Cell RNA - HL-60 [nTPM]":"59.3","Cell RNA - HMC-1 [nTPM]":"26.5","Cell RNA - HSkMC [nTPM]":"24.8","Cell RNA - hTCEpi [nTPM]":"22.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.0","Cell RNA - hTERT-HME1 [nTPM]":"27.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.3","Cell RNA - HUVEC TERT2 [nTPM]":"24.9","Cell RNA - JURKAT [nTPM]":"18.7","Cell RNA - K-562 [nTPM]":"26.3","Cell RNA - Karpas-707 [nTPM]":"43.9","Cell RNA - LHCN-M2 [nTPM]":"18.3","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"18.9","Cell RNA - NTERA-2 [nTPM]":"27.5","Cell RNA - OE19 [nTPM]":"38.3","Cell RNA - PC-3 [nTPM]":"15.2","Cell RNA - REH [nTPM]":"33.7","Cell RNA - RH-30 [nTPM]":"16.7","Cell RNA - RPMI-8226 [nTPM]":"21.3","Cell RNA - RPTEC TERT1 [nTPM]":"20.3","Cell RNA - RT4 [nTPM]":"40.4","Cell RNA - SCLC-21H [nTPM]":"11.3","Cell RNA - SH-SY5Y [nTPM]":"11.9","Cell RNA - SiHa [nTPM]":"51.1","Cell RNA - SK-BR-3 [nTPM]":"26.0","Cell RNA - SK-MEL-30 [nTPM]":"25.6","Cell RNA - SuSa [nTPM]":"29.5","Cell RNA - T-47d [nTPM]":"17.8","Cell RNA - THP-1 [nTPM]":"33.9","Cell RNA - TIME [nTPM]":"31.3","Cell RNA - U-138 MG [nTPM]":"20.3","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"16.3","Cell RNA - U-251 MG [nTPM]":"20.8","Cell RNA - U-266\/70 [nTPM]":"28.5","Cell RNA - U-266\/84 [nTPM]":"14.1","Cell RNA - U-698 [nTPM]":"47.9","Cell RNA - U-87 MG [nTPM]":"16.3","Cell RNA - U-937 [nTPM]":"17.4","Cell RNA - WM-115 [nTPM]":"21.5","Blood RNA - basophil [nTPM]":"3.6","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"1.5","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"1.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.7","Blood RNA - myeloid DC [nTPM]":"2.1","Blood RNA - naive B-cell [nTPM]":"1.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"6.8","Brain RNA - basal ganglia [nTPM]":"8.9","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"10.8","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"9.4","Brain RNA - medulla oblongata [nTPM]":"10.6","Brain RNA - midbrain [nTPM]":"7.8","Brain RNA - pons [nTPM]":"7.7","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"11.2","Single Cell Type RNA - Adipocytes [nTPM]":"45.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"67.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.2","Single Cell Type RNA - Astrocytes [nTPM]":"58.1","Single Cell Type RNA - B-cells [nTPM]":"53.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.9","Single Cell Type RNA - Bipolar cells [nTPM]":"44.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"35.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.4","Single Cell Type RNA - dendritic cells [nTPM]":"63.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.1","Single Cell Type RNA - Early spermatids [nTPM]":"15.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"56.4","Single Cell Type RNA - Endothelial cells [nTPM]":"36.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.7","Single Cell Type RNA - Erythroid cells [nTPM]":"60.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"71.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.9","Single Cell Type RNA - Fibroblasts [nTPM]":"32.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.5","Single Cell Type RNA - granulocytes [nTPM]":"25.3","Single Cell Type RNA - Granulosa cells [nTPM]":"36.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"29.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"73.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"60.7","Single Cell Type RNA - Langerhans cells [nTPM]":"25.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.9","Single Cell Type RNA - Macrophages [nTPM]":"60.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"52.0","Single Cell Type RNA - Muller glia cells [nTPM]":"27.7","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"81.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"80.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"25.8","Single Cell Type RNA - Paneth cells [nTPM]":"28.9","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"51.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.9","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"36.7","Single Cell Type RNA - Spermatocytes [nTPM]":"22.8","Single Cell Type RNA - Spermatogonia [nTPM]":"31.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"25.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.2","Single Cell Type RNA - T-cells [nTPM]":"46.0","Single Cell Type RNA - Theca cells [nTPM]":"36.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.7","Single Cell Type RNA - Urothelial cells [nTPM]":"36.3"},{"Gene":"EPAS1","Gene synonym":["bHLHe73","HIF2A","HLF","MOP2","PASD2"],"Ensembl":"ENSG00000116016","Gene description":"Endothelial PAS domain protein 1","Uniprot":["Q99814"],"Chromosome":"2","Position":"46293667-46386697","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Angiogenesis","Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Congenital erythrocytosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"412.0","placenta":"445.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"831.5","Endothelial cells":"425.8","Hepatic stellate cells":"538.7","Syncytiotrophoblasts":"349.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"18","RNA blood cell specific nTPM":{"basophil":"20.6","eosinophil":"8.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"26","RNA blood lineage specific nTPM":{"granulocytes":"20.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"267.3","BJ hTERT+":"266.7","HHSteC":"326.3","RT4":"339.8","TIME":"337.8","U-138 MG":"284.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031200","HPA069697"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031200":"AB_2673785","HPA069697":"AB_2732139"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.00e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.66e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Tissue RNA - adipose tissue [nTPM]":"296.0","Tissue RNA - adrenal gland [nTPM]":"52.1","Tissue RNA - amygdala [nTPM]":"53.4","Tissue RNA - appendix [nTPM]":"66.1","Tissue RNA - basal ganglia [nTPM]":"48.6","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"166.7","Tissue RNA - cerebellum [nTPM]":"44.6","Tissue RNA - cerebral cortex [nTPM]":"47.7","Tissue RNA - cervix [nTPM]":"72.9","Tissue RNA - choroid plexus [nTPM]":"139.1","Tissue RNA - colon [nTPM]":"57.1","Tissue RNA - duodenum [nTPM]":"46.3","Tissue RNA - endometrium 1 [nTPM]":"87.9","Tissue RNA - epididymis [nTPM]":"26.0","Tissue RNA - esophagus [nTPM]":"72.7","Tissue RNA - fallopian tube [nTPM]":"80.1","Tissue RNA - gallbladder [nTPM]":"83.2","Tissue RNA - heart muscle [nTPM]":"122.1","Tissue RNA - hippocampal formation [nTPM]":"39.2","Tissue RNA - hypothalamus [nTPM]":"44.7","Tissue RNA - kidney [nTPM]":"89.5","Tissue RNA - liver [nTPM]":"110.1","Tissue RNA - lung [nTPM]":"412.0","Tissue RNA - lymph node [nTPM]":"47.9","Tissue RNA - medulla oblongata [nTPM]":"60.5","Tissue RNA - midbrain [nTPM]":"54.2","Tissue RNA - ovary [nTPM]":"34.5","Tissue RNA - pancreas [nTPM]":"59.6","Tissue RNA - parathyroid gland [nTPM]":"79.4","Tissue RNA - pituitary gland [nTPM]":"25.9","Tissue RNA - placenta [nTPM]":"445.6","Tissue RNA - pons [nTPM]":"60.2","Tissue RNA - prostate [nTPM]":"51.8","Tissue RNA - rectum [nTPM]":"42.6","Tissue RNA - retina [nTPM]":"53.6","Tissue RNA - salivary gland [nTPM]":"40.0","Tissue RNA - seminal vesicle [nTPM]":"66.3","Tissue RNA - skeletal muscle [nTPM]":"80.5","Tissue RNA - skin 1 [nTPM]":"42.9","Tissue RNA - small intestine [nTPM]":"50.9","Tissue RNA - smooth muscle [nTPM]":"71.7","Tissue RNA - spinal cord [nTPM]":"45.6","Tissue RNA - spleen [nTPM]":"84.6","Tissue RNA - stomach 1 [nTPM]":"42.8","Tissue RNA - testis [nTPM]":"20.0","Tissue RNA - thalamus [nTPM]":"75.4","Tissue RNA - thymus [nTPM]":"17.9","Tissue RNA - thyroid gland [nTPM]":"138.1","Tissue RNA - tongue [nTPM]":"153.6","Tissue RNA - tonsil [nTPM]":"40.3","Tissue RNA - urinary bladder [nTPM]":"94.9","Tissue RNA - vagina [nTPM]":"47.8","Tissue RNA - white matter [nTPM]":"44.6","Cell RNA - A-431 [nTPM]":"32.2","Cell RNA - A549 [nTPM]":"33.5","Cell RNA - AF22 [nTPM]":"2.1","Cell RNA - AN3-CA [nTPM]":"2.5","Cell RNA - ASC diff [nTPM]":"153.8","Cell RNA - ASC TERT1 [nTPM]":"98.6","Cell RNA - BEWO [nTPM]":"267.3","Cell RNA - BJ [nTPM]":"98.7","Cell RNA - BJ hTERT+ [nTPM]":"266.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.1","Cell RNA - CACO-2 [nTPM]":"5.8","Cell RNA - CAPAN-2 [nTPM]":"5.5","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"23.8","Cell RNA - fHDF\/TERT166 [nTPM]":"188.5","Cell RNA - GAMG [nTPM]":"55.2","Cell RNA - HaCaT [nTPM]":"15.2","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"79.0","Cell RNA - HBF TERT88 [nTPM]":"41.3","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"10.3","Cell RNA - Hep G2 [nTPM]":"71.8","Cell RNA - HHSteC [nTPM]":"326.3","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"19.8","Cell RNA - HSkMC [nTPM]":"145.0","Cell RNA - hTCEpi [nTPM]":"106.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.7","Cell RNA - hTERT-HME1 [nTPM]":"75.8","Cell RNA - hTERT-RPE1 [nTPM]":"41.0","Cell RNA - HUVEC TERT2 [nTPM]":"193.1","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"3.1","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"34.2","Cell RNA - MCF7 [nTPM]":"27.8","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"1.3","Cell RNA - OE19 [nTPM]":"22.4","Cell RNA - PC-3 [nTPM]":"18.5","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"3.7","Cell RNA - RPMI-8226 [nTPM]":"10.5","Cell RNA - RPTEC TERT1 [nTPM]":"34.5","Cell RNA - RT4 [nTPM]":"339.8","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"68.5","Cell RNA - SiHa [nTPM]":"77.4","Cell RNA - SK-BR-3 [nTPM]":"175.5","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"68.3","Cell RNA - T-47d [nTPM]":"11.7","Cell RNA - THP-1 [nTPM]":"14.1","Cell RNA - TIME [nTPM]":"337.8","Cell RNA - U-138 MG [nTPM]":"284.0","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"38.3","Cell RNA - U-251 MG [nTPM]":"8.4","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"207.4","Cell RNA - U-937 [nTPM]":"5.4","Cell RNA - WM-115 [nTPM]":"7.4","Blood RNA - basophil [nTPM]":"20.6","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"8.4","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"53.4","Brain RNA - basal ganglia [nTPM]":"48.6","Brain RNA - cerebellum [nTPM]":"44.6","Brain RNA - cerebral cortex [nTPM]":"47.7","Brain RNA - hippocampal formation [nTPM]":"39.2","Brain RNA - hypothalamus [nTPM]":"44.7","Brain RNA - medulla oblongata [nTPM]":"60.5","Brain RNA - midbrain [nTPM]":"54.2","Brain RNA - pons [nTPM]":"60.2","Brain RNA - spinal cord [nTPM]":"45.6","Brain RNA - thalamus [nTPM]":"75.4","Brain RNA - white matter [nTPM]":"44.6","Single Cell Type RNA - Adipocytes [nTPM]":"831.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"151.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.4","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"48.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"69.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"108.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"29.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"79.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"124.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"126.2","Single Cell Type RNA - dendritic cells [nTPM]":"6.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"112.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.0","Single Cell Type RNA - Early spermatids [nTPM]":"12.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.7","Single Cell Type RNA - Endothelial cells [nTPM]":"425.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"52.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"299.9","Single Cell Type RNA - Fibroblasts [nTPM]":"76.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"67.6","Single Cell Type RNA - granulocytes [nTPM]":"41.2","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"538.7","Single Cell Type RNA - Hepatocytes [nTPM]":"78.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"55.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.9","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"60.9","Single Cell Type RNA - Langerhans cells [nTPM]":"30.3","Single Cell Type RNA - Late spermatids [nTPM]":"52.7","Single Cell Type RNA - Leydig cells [nTPM]":"12.5","Single Cell Type RNA - Macrophages [nTPM]":"21.4","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"155.5","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"95.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"31.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.1","Single Cell Type RNA - Paneth cells [nTPM]":"53.7","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"3.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"57.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"45.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"59.3","Single Cell Type RNA - Sertoli cells [nTPM]":"282.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"250.5","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"65.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"33.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"349.7","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"23.6","Single Cell Type RNA - Urothelial cells [nTPM]":"85.7"},{"Gene":"ERBB2","Gene synonym":["CD340","HER-2","HER2","NEU","NGL"],"Ensembl":"ENSG00000141736","Gene description":"Erb-b2 receptor tyrosine kinase 2","Uniprot":["P04626"],"Chromosome":"17","Position":"39687914-39730426","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"136.1","Distal enterocytes":"111.0","Proximal enterocytes":"121.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"5.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"T-cells":"5.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"41","RNA cell line specific nTPM":{"OE19":"6565.0","SK-BR-3":"3115.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000043","HPA001060","HPA001338","HPA001383","CAB020416","CAB062555"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"980000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB000043":"AB_2335701","CAB020416":"AB_442047","CAB062555":"AB_2665610","HPA001060":"AB_2666185","HPA001338":"AB_2666279","HPA001383":"AB_1078500"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.99e-8"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.04e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.17e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.41e-14"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.0","Tissue RNA - adrenal gland [nTPM]":"5.4","Tissue RNA - amygdala [nTPM]":"16.1","Tissue RNA - appendix [nTPM]":"12.1","Tissue RNA - basal ganglia [nTPM]":"20.5","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"56.0","Tissue RNA - cerebellum [nTPM]":"14.3","Tissue RNA - cerebral cortex [nTPM]":"13.1","Tissue RNA - cervix [nTPM]":"37.6","Tissue RNA - choroid plexus [nTPM]":"23.3","Tissue RNA - colon [nTPM]":"68.2","Tissue RNA - duodenum [nTPM]":"63.6","Tissue RNA - endometrium 1 [nTPM]":"25.2","Tissue RNA - epididymis [nTPM]":"26.6","Tissue RNA - esophagus [nTPM]":"102.4","Tissue RNA - fallopian tube [nTPM]":"64.2","Tissue RNA - gallbladder [nTPM]":"31.0","Tissue RNA - heart muscle [nTPM]":"57.0","Tissue RNA - hippocampal formation [nTPM]":"13.3","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"73.5","Tissue RNA - liver [nTPM]":"31.1","Tissue RNA - lung [nTPM]":"36.2","Tissue RNA - lymph node [nTPM]":"4.8","Tissue RNA - medulla oblongata [nTPM]":"22.4","Tissue RNA - midbrain [nTPM]":"22.7","Tissue RNA - ovary [nTPM]":"23.9","Tissue RNA - pancreas [nTPM]":"37.6","Tissue RNA - parathyroid gland [nTPM]":"81.7","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"27.0","Tissue RNA - pons [nTPM]":"17.1","Tissue RNA - prostate [nTPM]":"55.6","Tissue RNA - rectum [nTPM]":"48.5","Tissue RNA - retina [nTPM]":"8.1","Tissue RNA - salivary gland [nTPM]":"68.7","Tissue RNA - seminal vesicle [nTPM]":"50.5","Tissue RNA - skeletal muscle [nTPM]":"20.7","Tissue RNA - skin 1 [nTPM]":"91.0","Tissue RNA - small intestine [nTPM]":"67.3","Tissue RNA - smooth muscle [nTPM]":"25.0","Tissue RNA - spinal cord [nTPM]":"18.5","Tissue RNA - spleen [nTPM]":"6.9","Tissue RNA - stomach 1 [nTPM]":"49.7","Tissue RNA - testis [nTPM]":"11.7","Tissue RNA - thalamus [nTPM]":"15.4","Tissue RNA - thymus [nTPM]":"7.4","Tissue RNA - thyroid gland [nTPM]":"56.5","Tissue RNA - tongue [nTPM]":"15.0","Tissue RNA - tonsil [nTPM]":"28.0","Tissue RNA - urinary bladder [nTPM]":"40.0","Tissue RNA - vagina [nTPM]":"52.9","Tissue RNA - white matter [nTPM]":"16.4","Cell RNA - A-431 [nTPM]":"38.7","Cell RNA - A549 [nTPM]":"45.7","Cell RNA - AF22 [nTPM]":"50.4","Cell RNA - AN3-CA [nTPM]":"31.7","Cell RNA - ASC diff [nTPM]":"59.3","Cell RNA - ASC TERT1 [nTPM]":"41.2","Cell RNA - BEWO [nTPM]":"67.7","Cell RNA - BJ [nTPM]":"27.2","Cell RNA - BJ hTERT+ [nTPM]":"44.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"58.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.9","Cell RNA - CACO-2 [nTPM]":"34.4","Cell RNA - CAPAN-2 [nTPM]":"102.7","Cell RNA - Daudi [nTPM]":"2.9","Cell RNA - EFO-21 [nTPM]":"54.6","Cell RNA - fHDF\/TERT166 [nTPM]":"62.7","Cell RNA - GAMG [nTPM]":"31.5","Cell RNA - HaCaT [nTPM]":"117.6","Cell RNA - HAP1 [nTPM]":"2.8","Cell RNA - HBEC3-KT [nTPM]":"61.2","Cell RNA - HBF TERT88 [nTPM]":"26.9","Cell RNA - HDLM-2 [nTPM]":"5.2","Cell RNA - HEK 293 [nTPM]":"38.6","Cell RNA - HEL [nTPM]":"1.8","Cell RNA - HeLa [nTPM]":"36.0","Cell RNA - Hep G2 [nTPM]":"56.3","Cell RNA - HHSteC [nTPM]":"35.3","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"1.0","Cell RNA - HSkMC [nTPM]":"41.0","Cell RNA - hTCEpi [nTPM]":"56.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.2","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"56.2","Cell RNA - HUVEC TERT2 [nTPM]":"24.4","Cell RNA - JURKAT [nTPM]":"1.9","Cell RNA - K-562 [nTPM]":"6.2","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"43.3","Cell RNA - MCF7 [nTPM]":"59.4","Cell RNA - MOLT-4 [nTPM]":"7.1","Cell RNA - NB-4 [nTPM]":"3.0","Cell RNA - NTERA-2 [nTPM]":"90.7","Cell RNA - OE19 [nTPM]":"6565.0","Cell RNA - PC-3 [nTPM]":"11.7","Cell RNA - REH [nTPM]":"3.9","Cell RNA - RH-30 [nTPM]":"20.5","Cell RNA - RPMI-8226 [nTPM]":"5.4","Cell RNA - RPTEC TERT1 [nTPM]":"58.9","Cell RNA - RT4 [nTPM]":"118.9","Cell RNA - SCLC-21H [nTPM]":"9.4","Cell RNA - SH-SY5Y [nTPM]":"2.6","Cell RNA - SiHa [nTPM]":"51.5","Cell RNA - SK-BR-3 [nTPM]":"3115.9","Cell RNA - SK-MEL-30 [nTPM]":"16.9","Cell RNA - SuSa [nTPM]":"62.2","Cell RNA - T-47d [nTPM]":"88.1","Cell RNA - THP-1 [nTPM]":"2.2","Cell RNA - TIME [nTPM]":"2.9","Cell RNA - U-138 MG [nTPM]":"30.2","Cell RNA - U-2 OS [nTPM]":"37.7","Cell RNA - U-2197 [nTPM]":"37.7","Cell RNA - U-251 MG [nTPM]":"17.6","Cell RNA - U-266\/70 [nTPM]":"5.3","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"3.6","Cell RNA - U-87 MG [nTPM]":"3.0","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"98.5","Blood RNA - basophil [nTPM]":"1.1","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"5.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"0.6","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"1.2","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"16.1","Brain RNA - basal ganglia [nTPM]":"20.5","Brain RNA - cerebellum [nTPM]":"14.3","Brain RNA - cerebral cortex [nTPM]":"13.1","Brain RNA - hippocampal formation [nTPM]":"13.3","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"22.4","Brain RNA - midbrain [nTPM]":"22.7","Brain RNA - pons [nTPM]":"17.1","Brain RNA - spinal cord [nTPM]":"18.5","Brain RNA - thalamus [nTPM]":"15.4","Brain RNA - white matter [nTPM]":"16.4","Single Cell Type RNA - Adipocytes [nTPM]":"3.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"2.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"62.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"34.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"43.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"136.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - dendritic cells [nTPM]":"5.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"111.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"30.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.9","Single Cell Type RNA - Endothelial cells [nTPM]":"6.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.6","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.8","Single Cell Type RNA - Fibroblasts [nTPM]":"15.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"53.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"61.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"20.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"10.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"47.5","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"2.2","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"1.2","Single Cell Type RNA - Muller glia cells [nTPM]":"24.1","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.5","Single Cell Type RNA - Paneth cells [nTPM]":"54.8","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"121.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"19.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.8","Single Cell Type RNA - Spermatogonia [nTPM]":"5.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.7","Single Cell Type RNA - T-cells [nTPM]":"2.8","Single Cell Type RNA - Theca cells [nTPM]":"4.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"75.4","Single Cell Type RNA - Urothelial cells [nTPM]":"31.3"},{"Gene":"EREG","Gene synonym":["ER"],"Ensembl":"ENSG00000124882","Gene description":"Epiregulin","Uniprot":["O14944"],"Chromosome":"4","Position":"74365145-74388749","Protein class":["Human disease related genes","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Differentiation"],"Molecular function":["Developmental protein","Growth factor","Mitogen"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"bone marrow":"129.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal respiratory cells":"179.1","Kupffer cells":"133.9","Langerhans cells":"171.1","Macrophages":"570.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"11.3"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"270.0","CAPAN-2":"76.7","hTEC\/SVTERT24-B":"83.7","U-2197":"181.4","U-87 MG":"307.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054373"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":46000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Neutrophils - Humoral immune response","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA054373":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.67e-7"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.56e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.45e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.57e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.5","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"10.3","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"129.0","Tissue RNA - breast [nTPM]":"2.5","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"1.9","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"0.2","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"12.6","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"2.7","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.4","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"1.3","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.2","Tissue RNA - skin 1 [nTPM]":"9.3","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"3.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.5","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.6","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"41.1","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"3.8","Cell RNA - ASC TERT1 [nTPM]":"6.6","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"270.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.6","Cell RNA - CACO-2 [nTPM]":"32.5","Cell RNA - CAPAN-2 [nTPM]":"76.7","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"44.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"20.1","Cell RNA - HaCaT [nTPM]":"2.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"59.3","Cell RNA - HBF TERT88 [nTPM]":"2.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.2","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"1.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"3.9","Cell RNA - hTCEpi [nTPM]":"20.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"83.7","Cell RNA - hTERT-HME1 [nTPM]":"43.5","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"1.6","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"27.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.6","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"181.4","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"307.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.4","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.6","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"4.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"5.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"179.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"24.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"82.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"2.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.6","Single Cell Type RNA - Erythroid cells [nTPM]":"17.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"4.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.9","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.2","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"133.9","Single Cell Type RNA - Langerhans cells [nTPM]":"171.1","Single Cell Type RNA - Late spermatids [nTPM]":"1.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"570.7","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"23.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.8","Single Cell Type RNA - Paneth cells [nTPM]":"27.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"11.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"33.1","Single Cell Type RNA - Urothelial cells [nTPM]":"7.4"},{"Gene":"ERG","Gene synonym":["erg-3","p55"],"Ensembl":"ENSG00000157554","Gene description":"ETS transcription factor ERG","Uniprot":["P11308"],"Chromosome":"21","Position":"38380027-38661780","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"94.4","Endothelial cells":"105.5","Hepatic stellate cells":"69.9","Microglial cells":"88.1"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"prostate cancer":"18.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"HUVEC TERT2":"138.3","MOLT-4":"47.7","REH":"151.5","TIME":"113.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018377","HPA046598"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB018377":"AB_675518","HPA046598":"AB_2679715"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.18e-6"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.44e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.64e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.03e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.94e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.63e-3"},"Tissue RNA - adipose tissue [nTPM]":"24.6","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"7.6","Tissue RNA - breast [nTPM]":"20.0","Tissue RNA - cerebellum [nTPM]":"5.0","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"5.4","Tissue RNA - duodenum [nTPM]":"3.4","Tissue RNA - endometrium 1 [nTPM]":"11.6","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"5.2","Tissue RNA - fallopian tube [nTPM]":"9.1","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"12.8","Tissue RNA - liver [nTPM]":"6.1","Tissue RNA - lung [nTPM]":"19.6","Tissue RNA - lymph node [nTPM]":"7.5","Tissue RNA - medulla oblongata [nTPM]":"5.9","Tissue RNA - midbrain [nTPM]":"5.4","Tissue RNA - ovary [nTPM]":"4.4","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"2.4","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"24.3","Tissue RNA - pons [nTPM]":"6.2","Tissue RNA - prostate [nTPM]":"7.1","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"7.9","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"6.5","Tissue RNA - smooth muscle [nTPM]":"12.0","Tissue RNA - spinal cord [nTPM]":"4.7","Tissue RNA - spleen [nTPM]":"26.6","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"1.5","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"9.2","Tissue RNA - vagina [nTPM]":"6.9","Tissue RNA - white matter [nTPM]":"5.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"1.6","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"22.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.9","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"138.3","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.0","Cell RNA - MOLT-4 [nTPM]":"47.7","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"151.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.1","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"113.4","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.7","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"5.0","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"5.9","Brain RNA - midbrain [nTPM]":"5.4","Brain RNA - pons [nTPM]":"6.2","Brain RNA - spinal cord [nTPM]":"4.7","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"5.4","Single Cell Type RNA - Adipocytes [nTPM]":"94.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"105.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"13.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.1","Single Cell Type RNA - granulocytes [nTPM]":"24.0","Single Cell Type RNA - Granulosa cells [nTPM]":"4.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"69.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"5.9","Single Cell Type RNA - Langerhans cells [nTPM]":"3.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.9","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"88.1","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"ESR1","Gene synonym":["ER-alpha","Era","ESR","NR3A1"],"Ensembl":"ENSG00000091831","Gene description":"Estrogen receptor 1","Uniprot":["P03372"],"Chromosome":"6","Position":"151656691-152129619","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"83.8","endometrium 1":"110.9","fallopian tube":"64.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"86.6","Endometrial ciliated cells":"77.9","Endometrial stromal cells":"79.9","Glandular and luminal cells":"98.9","Hepatocytes":"52.1","Horizontal cells":"62.2","Skeletal myocytes":"56.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"40.2","endometrial cancer":"24.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"MCF7":"46.0","T-47d":"57.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000037","HPA000449","HPA000450","CAB055099","CAB072858"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 6: T47d - Mammary gland","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB000037":"AB_563706","CAB055099":"AB_2101946","CAB072858":"AB_2665701","HPA000449":"AB_1078753","HPA000450":"AB_1078754"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.47e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.10e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.91e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Tissue RNA - adipose tissue [nTPM]":"4.2","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.8","Tissue RNA - breast [nTPM]":"29.1","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"83.8","Tissue RNA - choroid plexus [nTPM]":"3.2","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"110.9","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"64.9","Tissue RNA - gallbladder [nTPM]":"1.2","Tissue RNA - heart muscle [nTPM]":"1.8","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"6.7","Tissue RNA - kidney [nTPM]":"2.8","Tissue RNA - liver [nTPM]":"16.9","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"0.4","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"6.6","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.3","Tissue RNA - prostate [nTPM]":"6.1","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"3.5","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"9.8","Tissue RNA - skeletal muscle [nTPM]":"5.8","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"50.4","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.7","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"5.9","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"2.6","Tissue RNA - tonsil [nTPM]":"2.3","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"46.9","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"1.9","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.3","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"1.2","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"46.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.7","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"57.4","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"5.2","Cell RNA - U-266\/84 [nTPM]":"1.1","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"6.7","Brain RNA - medulla oblongata [nTPM]":"0.4","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.3","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"5.9","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"86.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"40.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"77.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"79.9","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"98.9","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"36.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"52.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.9","Single Cell Type RNA - Horizontal cells [nTPM]":"62.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"4.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.1","Single Cell Type RNA - Late spermatids [nTPM]":"10.3","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"2.2","Single Cell Type RNA - Plasma cells [nTPM]":"8.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"56.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"4.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"6.8"},{"Gene":"ETNK1","Gene synonym":["EKI","EKI1"],"Ensembl":"ENSG00000139163","Gene description":"Ethanolamine kinase 1","Uniprot":["Q9HBU6"],"Chromosome":"12","Position":"22625075-22690665","Protein class":["Cancer-related genes","Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"299.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010712","HPA029407"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 45: Intestine - Brush border","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 23: Spermatids - Flagellum & Golgi organization","Subcellular main location":["Nucleoplasm","Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA010712":"AB_2668349","HPA029407":"AB_2673026"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.79e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.85e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.98e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.30e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.75e-4"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"14.4","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"14.5","Tissue RNA - basal ganglia [nTPM]":"15.2","Tissue RNA - bone marrow [nTPM]":"12.2","Tissue RNA - breast [nTPM]":"13.7","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"15.9","Tissue RNA - cervix [nTPM]":"10.8","Tissue RNA - choroid plexus [nTPM]":"16.4","Tissue RNA - colon [nTPM]":"27.2","Tissue RNA - duodenum [nTPM]":"23.3","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"19.6","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"10.1","Tissue RNA - gallbladder [nTPM]":"14.0","Tissue RNA - heart muscle [nTPM]":"7.3","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"28.1","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"18.2","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"17.4","Tissue RNA - medulla oblongata [nTPM]":"12.0","Tissue RNA - midbrain [nTPM]":"14.2","Tissue RNA - ovary [nTPM]":"11.7","Tissue RNA - pancreas [nTPM]":"10.7","Tissue RNA - parathyroid gland [nTPM]":"10.8","Tissue RNA - pituitary gland [nTPM]":"13.7","Tissue RNA - placenta [nTPM]":"11.3","Tissue RNA - pons [nTPM]":"15.8","Tissue RNA - prostate [nTPM]":"10.9","Tissue RNA - rectum [nTPM]":"15.3","Tissue RNA - retina [nTPM]":"18.2","Tissue RNA - salivary gland [nTPM]":"12.4","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"6.2","Tissue RNA - skin 1 [nTPM]":"15.3","Tissue RNA - small intestine [nTPM]":"15.5","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"11.1","Tissue RNA - spleen [nTPM]":"16.7","Tissue RNA - stomach 1 [nTPM]":"45.0","Tissue RNA - testis [nTPM]":"17.8","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"23.1","Tissue RNA - thyroid gland [nTPM]":"14.5","Tissue RNA - tongue [nTPM]":"5.6","Tissue RNA - tonsil [nTPM]":"14.3","Tissue RNA - urinary bladder [nTPM]":"10.8","Tissue RNA - vagina [nTPM]":"9.5","Tissue RNA - white matter [nTPM]":"17.5","Cell RNA - A-431 [nTPM]":"14.8","Cell RNA - A549 [nTPM]":"27.9","Cell RNA - AF22 [nTPM]":"30.4","Cell RNA - AN3-CA [nTPM]":"27.5","Cell RNA - ASC diff [nTPM]":"21.2","Cell RNA - ASC TERT1 [nTPM]":"21.3","Cell RNA - BEWO [nTPM]":"21.7","Cell RNA - BJ [nTPM]":"15.6","Cell RNA - BJ hTERT+ [nTPM]":"12.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"17.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.0","Cell RNA - CACO-2 [nTPM]":"20.6","Cell RNA - CAPAN-2 [nTPM]":"33.3","Cell RNA - Daudi [nTPM]":"41.1","Cell RNA - EFO-21 [nTPM]":"14.7","Cell RNA - fHDF\/TERT166 [nTPM]":"11.6","Cell RNA - GAMG [nTPM]":"16.5","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"27.1","Cell RNA - HBEC3-KT [nTPM]":"7.6","Cell RNA - HBF TERT88 [nTPM]":"28.2","Cell RNA - HDLM-2 [nTPM]":"36.8","Cell RNA - HEK 293 [nTPM]":"23.7","Cell RNA - HEL [nTPM]":"34.7","Cell RNA - HeLa [nTPM]":"11.5","Cell RNA - Hep G2 [nTPM]":"18.9","Cell RNA - HHSteC [nTPM]":"20.6","Cell RNA - HL-60 [nTPM]":"33.9","Cell RNA - HMC-1 [nTPM]":"29.4","Cell RNA - HSkMC [nTPM]":"13.7","Cell RNA - hTCEpi [nTPM]":"7.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"17.4","Cell RNA - hTERT-RPE1 [nTPM]":"25.8","Cell RNA - HUVEC TERT2 [nTPM]":"20.3","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"41.8","Cell RNA - Karpas-707 [nTPM]":"17.2","Cell RNA - LHCN-M2 [nTPM]":"22.3","Cell RNA - MCF7 [nTPM]":"7.7","Cell RNA - MOLT-4 [nTPM]":"38.8","Cell RNA - NB-4 [nTPM]":"67.1","Cell RNA - NTERA-2 [nTPM]":"59.3","Cell RNA - OE19 [nTPM]":"17.9","Cell RNA - PC-3 [nTPM]":"20.1","Cell RNA - REH [nTPM]":"32.7","Cell RNA - RH-30 [nTPM]":"28.1","Cell RNA - RPMI-8226 [nTPM]":"32.9","Cell RNA - RPTEC TERT1 [nTPM]":"25.6","Cell RNA - RT4 [nTPM]":"16.5","Cell RNA - SCLC-21H [nTPM]":"9.8","Cell RNA - SH-SY5Y [nTPM]":"17.8","Cell RNA - SiHa [nTPM]":"18.9","Cell RNA - SK-BR-3 [nTPM]":"13.9","Cell RNA - SK-MEL-30 [nTPM]":"27.1","Cell RNA - SuSa [nTPM]":"41.1","Cell RNA - T-47d [nTPM]":"24.1","Cell RNA - THP-1 [nTPM]":"32.1","Cell RNA - TIME [nTPM]":"17.5","Cell RNA - U-138 MG [nTPM]":"12.2","Cell RNA - U-2 OS [nTPM]":"19.9","Cell RNA - U-2197 [nTPM]":"18.6","Cell RNA - U-251 MG [nTPM]":"25.0","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"18.1","Cell RNA - U-698 [nTPM]":"46.8","Cell RNA - U-87 MG [nTPM]":"16.2","Cell RNA - U-937 [nTPM]":"21.0","Cell RNA - WM-115 [nTPM]":"23.9","Blood RNA - basophil [nTPM]":"44.0","Blood RNA - classical monocyte [nTPM]":"14.3","Blood RNA - eosinophil [nTPM]":"15.9","Blood RNA - gdT-cell [nTPM]":"15.4","Blood RNA - intermediate monocyte [nTPM]":"22.0","Blood RNA - MAIT T-cell [nTPM]":"15.2","Blood RNA - memory B-cell [nTPM]":"22.2","Blood RNA - memory CD4 T-cell [nTPM]":"16.4","Blood RNA - memory CD8 T-cell [nTPM]":"14.4","Blood RNA - myeloid DC [nTPM]":"14.1","Blood RNA - naive B-cell [nTPM]":"15.3","Blood RNA - naive CD4 T-cell [nTPM]":"17.7","Blood RNA - naive CD8 T-cell [nTPM]":"17.7","Blood RNA - neutrophil [nTPM]":"14.6","Blood RNA - NK-cell [nTPM]":"17.7","Blood RNA - non-classical monocyte [nTPM]":"23.4","Blood RNA - plasmacytoid DC [nTPM]":"12.6","Blood RNA - T-reg [nTPM]":"20.5","Blood RNA - total PBMC [nTPM]":"19.2","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"15.2","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"15.9","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"28.1","Brain RNA - medulla oblongata [nTPM]":"12.0","Brain RNA - midbrain [nTPM]":"14.2","Brain RNA - pons [nTPM]":"15.8","Brain RNA - spinal cord [nTPM]":"11.1","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"17.5","Single Cell Type RNA - Adipocytes [nTPM]":"33.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.2","Single Cell Type RNA - Astrocytes [nTPM]":"48.0","Single Cell Type RNA - B-cells [nTPM]":"55.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"144.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"75.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.9","Single Cell Type RNA - Bipolar cells [nTPM]":"41.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"56.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"43.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"30.1","Single Cell Type RNA - dendritic cells [nTPM]":"57.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"116.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"30.7","Single Cell Type RNA - Early spermatids [nTPM]":"299.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"64.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.1","Single Cell Type RNA - Endothelial cells [nTPM]":"34.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"108.3","Single Cell Type RNA - Erythroid cells [nTPM]":"48.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"104.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"44.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.2","Single Cell Type RNA - Fibroblasts [nTPM]":"38.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"230.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"51.4","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"40.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.2","Single Cell Type RNA - Hepatocytes [nTPM]":"41.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.9","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"104.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"60.7","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"88.3","Single Cell Type RNA - Langerhans cells [nTPM]":"60.0","Single Cell Type RNA - Late spermatids [nTPM]":"43.5","Single Cell Type RNA - Leydig cells [nTPM]":"24.2","Single Cell Type RNA - Macrophages [nTPM]":"57.0","Single Cell Type RNA - Melanocytes [nTPM]":"67.6","Single Cell Type RNA - Microglial cells [nTPM]":"84.3","Single Cell Type RNA - monocytes [nTPM]":"39.1","Single Cell Type RNA - Muller glia cells [nTPM]":"17.7","Single Cell Type RNA - NK-cells [nTPM]":"43.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"121.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"152.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"39.5","Single Cell Type RNA - Paneth cells [nTPM]":"62.9","Single Cell Type RNA - Peritubular cells [nTPM]":"21.4","Single Cell Type RNA - Plasma cells [nTPM]":"63.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"57.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"81.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.5","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"38.9","Single Cell Type RNA - Spermatocytes [nTPM]":"49.1","Single Cell Type RNA - Spermatogonia [nTPM]":"18.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"51.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"170.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"75.4","Single Cell Type RNA - T-cells [nTPM]":"49.0","Single Cell Type RNA - Theca cells [nTPM]":"41.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"47.8","Single Cell Type RNA - Urothelial cells [nTPM]":"90.3"},{"Gene":"ETV1","Gene synonym":["ER81"],"Ensembl":"ENSG00000006468","Gene description":"ETS variant transcription factor 1","Uniprot":["P50549"],"Chromosome":"7","Position":"13891229-13991425","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"119.9","salivary gland":"91.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"137.7","Astrocytes":"67.3","Cardiomyocytes":"87.7","Enteroendocrine cells":"198.1","Excitatory neurons":"66.9","Oligodendrocyte precursor cells":"135.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"22.5"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"119.9","thalamus":"32.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"67.8","hTERT-RPE1":"76.2","SCLC-21H":"79.3","U-87 MG":"157.2","WM-115":"78.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"200.7"},"Antibody":["HPA068389","HPA077249"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA068389":null,"HPA077249":"AB_2686829"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.9","Tissue RNA - adrenal gland [nTPM]":"23.0","Tissue RNA - amygdala [nTPM]":"13.6","Tissue RNA - appendix [nTPM]":"1.9","Tissue RNA - basal ganglia [nTPM]":"10.9","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"8.2","Tissue RNA - cerebellum [nTPM]":"119.9","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"2.3","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"4.1","Tissue RNA - duodenum [nTPM]":"2.2","Tissue RNA - endometrium 1 [nTPM]":"4.4","Tissue RNA - epididymis [nTPM]":"2.3","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"1.5","Tissue RNA - gallbladder [nTPM]":"17.3","Tissue RNA - heart muscle [nTPM]":"35.6","Tissue RNA - hippocampal formation [nTPM]":"14.6","Tissue RNA - hypothalamus [nTPM]":"5.6","Tissue RNA - kidney [nTPM]":"3.2","Tissue RNA - liver [nTPM]":"3.9","Tissue RNA - lung [nTPM]":"28.7","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"14.0","Tissue RNA - ovary [nTPM]":"1.4","Tissue RNA - pancreas [nTPM]":"3.1","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"7.4","Tissue RNA - placenta [nTPM]":"3.5","Tissue RNA - pons [nTPM]":"9.0","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"4.3","Tissue RNA - retina [nTPM]":"4.5","Tissue RNA - salivary gland [nTPM]":"91.6","Tissue RNA - seminal vesicle [nTPM]":"12.6","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"1.9","Tissue RNA - small intestine [nTPM]":"3.5","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"9.1","Tissue RNA - stomach 1 [nTPM]":"2.6","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"32.8","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"12.2","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"1.9","Tissue RNA - urinary bladder [nTPM]":"2.7","Tissue RNA - vagina [nTPM]":"1.5","Tissue RNA - white matter [nTPM]":"8.1","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"4.9","Cell RNA - AF22 [nTPM]":"35.5","Cell RNA - AN3-CA [nTPM]":"67.8","Cell RNA - ASC diff [nTPM]":"12.1","Cell RNA - ASC TERT1 [nTPM]":"35.4","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"3.2","Cell RNA - BJ hTERT+ [nTPM]":"12.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"16.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"3.6","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"9.8","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"3.8","Cell RNA - HBF TERT88 [nTPM]":"4.3","Cell RNA - HDLM-2 [nTPM]":"0.9","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"2.1","Cell RNA - HeLa [nTPM]":"3.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"7.1","Cell RNA - HL-60 [nTPM]":"12.3","Cell RNA - HMC-1 [nTPM]":"4.5","Cell RNA - HSkMC [nTPM]":"10.7","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"23.3","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"76.2","Cell RNA - HUVEC TERT2 [nTPM]":"15.3","Cell RNA - JURKAT [nTPM]":"1.1","Cell RNA - K-562 [nTPM]":"11.0","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"14.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"53.2","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"36.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"21.5","Cell RNA - RPMI-8226 [nTPM]":"2.9","Cell RNA - RPTEC TERT1 [nTPM]":"23.7","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"79.3","Cell RNA - SH-SY5Y [nTPM]":"15.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"1.2","Cell RNA - SK-MEL-30 [nTPM]":"19.6","Cell RNA - SuSa [nTPM]":"12.2","Cell RNA - T-47d [nTPM]":"1.2","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"8.6","Cell RNA - U-138 MG [nTPM]":"7.0","Cell RNA - U-2 OS [nTPM]":"2.2","Cell RNA - U-2197 [nTPM]":"13.8","Cell RNA - U-251 MG [nTPM]":"13.4","Cell RNA - U-266\/70 [nTPM]":"12.2","Cell RNA - U-266\/84 [nTPM]":"4.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"157.2","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"78.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.6","Brain RNA - basal ganglia [nTPM]":"10.9","Brain RNA - cerebellum [nTPM]":"119.9","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"14.6","Brain RNA - hypothalamus [nTPM]":"5.6","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"14.0","Brain RNA - pons [nTPM]":"9.0","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"32.8","Brain RNA - white matter [nTPM]":"8.1","Single Cell Type RNA - Adipocytes [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"137.7","Single Cell Type RNA - Astrocytes [nTPM]":"67.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"4.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"23.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"87.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.6","Single Cell Type RNA - Early spermatids [nTPM]":"25.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.9","Single Cell Type RNA - Endothelial cells [nTPM]":"11.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"198.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"66.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"17.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.9","Single Cell Type RNA - Hepatocytes [nTPM]":"13.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.4","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.4","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"7.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.7","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"135.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"34.6","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"9.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"ETV4","Gene synonym":["E1A-F","E1AF","PEA3"],"Ensembl":"ENSG00000175832","Gene description":"ETS variant transcription factor 4","Uniprot":["P43268"],"Chromosome":"17","Position":"43527844-43579620","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal squamous epithelial cells":"23.3","Cholangiocytes":"17.2","Distal tubular cells":"17.6","Enteroendocrine cells":"14.9","Extravillous trophoblasts":"19.8","Syncytiotrophoblasts":"14.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"80.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"177.7","Hep G2":"173.0","SK-MEL-30":"197.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005768"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli rim","Mitotic chromosome"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Salivary gland - Salivary secretion","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoli rim"],"Subcellular additional location":["Mitotic chromosome"],"Antibody RRID":{"HPA005768":"AB_1848294"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.03e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.60e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"2.4","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"7.0","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"2.2","Tissue RNA - cervix [nTPM]":"3.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"2.0","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"2.4","Tissue RNA - epididymis [nTPM]":"1.0","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"2.5","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"3.1","Tissue RNA - hippocampal formation [nTPM]":"1.3","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"5.4","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"2.2","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"14.7","Tissue RNA - placenta [nTPM]":"5.2","Tissue RNA - pons [nTPM]":"1.4","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"1.7","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"3.6","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"4.2","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"3.8","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"0.7","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"6.9","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"4.8","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"24.5","Cell RNA - A549 [nTPM]":"67.0","Cell RNA - AF22 [nTPM]":"80.4","Cell RNA - AN3-CA [nTPM]":"177.7","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"20.1","Cell RNA - BEWO [nTPM]":"17.9","Cell RNA - BJ [nTPM]":"7.9","Cell RNA - BJ hTERT+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.2","Cell RNA - CACO-2 [nTPM]":"38.1","Cell RNA - CAPAN-2 [nTPM]":"33.9","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"4.3","Cell RNA - fHDF\/TERT166 [nTPM]":"4.1","Cell RNA - GAMG [nTPM]":"36.6","Cell RNA - HaCaT [nTPM]":"43.6","Cell RNA - HAP1 [nTPM]":"2.7","Cell RNA - HBEC3-KT [nTPM]":"40.2","Cell RNA - HBF TERT88 [nTPM]":"13.2","Cell RNA - HDLM-2 [nTPM]":"0.8","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"2.3","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"173.0","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"47.0","Cell RNA - HMC-1 [nTPM]":"20.9","Cell RNA - HSkMC [nTPM]":"3.6","Cell RNA - hTCEpi [nTPM]":"1.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.8","Cell RNA - hTERT-HME1 [nTPM]":"35.0","Cell RNA - hTERT-RPE1 [nTPM]":"16.8","Cell RNA - HUVEC TERT2 [nTPM]":"32.1","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"48.9","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"31.0","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"82.9","Cell RNA - NTERA-2 [nTPM]":"116.9","Cell RNA - OE19 [nTPM]":"123.1","Cell RNA - PC-3 [nTPM]":"110.9","Cell RNA - REH [nTPM]":"99.8","Cell RNA - RH-30 [nTPM]":"9.8","Cell RNA - RPMI-8226 [nTPM]":"58.9","Cell RNA - RPTEC TERT1 [nTPM]":"33.0","Cell RNA - RT4 [nTPM]":"17.3","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"71.4","Cell RNA - SiHa [nTPM]":"2.1","Cell RNA - SK-BR-3 [nTPM]":"4.5","Cell RNA - SK-MEL-30 [nTPM]":"197.0","Cell RNA - SuSa [nTPM]":"43.8","Cell RNA - T-47d [nTPM]":"0.8","Cell RNA - THP-1 [nTPM]":"13.9","Cell RNA - TIME [nTPM]":"15.1","Cell RNA - U-138 MG [nTPM]":"10.6","Cell RNA - U-2 OS [nTPM]":"52.0","Cell RNA - U-2197 [nTPM]":"15.7","Cell RNA - U-251 MG [nTPM]":"22.1","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"47.8","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"18.9","Cell RNA - U-937 [nTPM]":"8.9","Cell RNA - WM-115 [nTPM]":"63.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"2.2","Brain RNA - hippocampal formation [nTPM]":"1.3","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.4","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.7","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"3.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"6.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"19.8","Single Cell Type RNA - Fibroblasts [nTPM]":"1.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.3","Single Cell Type RNA - Late spermatids [nTPM]":"6.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"10.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"3.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.9","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.7","Single Cell Type RNA - Urothelial cells [nTPM]":"4.3"},{"Gene":"ETV5","Gene synonym":["ERM"],"Ensembl":"ENSG00000244405","Gene description":"ETS variant transcription factor 5","Uniprot":["P41161"],"Chromosome":"3","Position":"186046314-186110318","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"94.0","Oligodendrocyte precursor cells":"169.9","Syncytiotrophoblasts":"88.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"melanoma":"50.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-MEL-30":"178.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009590","HPA063065","HPA073889"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009590":"AB_2101008","HPA063065":"AB_2684936","HPA073889":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.85e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.84e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"39.3","Tissue RNA - amygdala [nTPM]":"17.1","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"22.4","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"17.7","Tissue RNA - cerebral cortex [nTPM]":"24.4","Tissue RNA - cervix [nTPM]":"4.9","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"5.6","Tissue RNA - heart muscle [nTPM]":"11.5","Tissue RNA - hippocampal formation [nTPM]":"17.8","Tissue RNA - hypothalamus [nTPM]":"16.8","Tissue RNA - kidney [nTPM]":"8.9","Tissue RNA - liver [nTPM]":"7.9","Tissue RNA - lung [nTPM]":"29.6","Tissue RNA - lymph node [nTPM]":"5.2","Tissue RNA - medulla oblongata [nTPM]":"20.5","Tissue RNA - midbrain [nTPM]":"17.1","Tissue RNA - ovary [nTPM]":"2.2","Tissue RNA - pancreas [nTPM]":"17.5","Tissue RNA - parathyroid gland [nTPM]":"42.2","Tissue RNA - pituitary gland [nTPM]":"25.4","Tissue RNA - placenta [nTPM]":"17.1","Tissue RNA - pons [nTPM]":"17.7","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"3.2","Tissue RNA - retina [nTPM]":"15.9","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"11.9","Tissue RNA - skin 1 [nTPM]":"6.4","Tissue RNA - small intestine [nTPM]":"3.0","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"14.7","Tissue RNA - spleen [nTPM]":"10.9","Tissue RNA - stomach 1 [nTPM]":"14.8","Tissue RNA - testis [nTPM]":"9.3","Tissue RNA - thalamus [nTPM]":"17.2","Tissue RNA - thymus [nTPM]":"4.8","Tissue RNA - thyroid gland [nTPM]":"21.9","Tissue RNA - tongue [nTPM]":"7.0","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"4.3","Tissue RNA - vagina [nTPM]":"4.1","Tissue RNA - white matter [nTPM]":"19.6","Cell RNA - A-431 [nTPM]":"42.4","Cell RNA - A549 [nTPM]":"28.6","Cell RNA - AF22 [nTPM]":"36.1","Cell RNA - AN3-CA [nTPM]":"79.2","Cell RNA - ASC diff [nTPM]":"21.9","Cell RNA - ASC TERT1 [nTPM]":"22.7","Cell RNA - BEWO [nTPM]":"2.6","Cell RNA - BJ [nTPM]":"35.7","Cell RNA - BJ hTERT+ [nTPM]":"39.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.6","Cell RNA - CACO-2 [nTPM]":"31.7","Cell RNA - CAPAN-2 [nTPM]":"25.4","Cell RNA - Daudi [nTPM]":"1.1","Cell RNA - EFO-21 [nTPM]":"46.4","Cell RNA - fHDF\/TERT166 [nTPM]":"34.7","Cell RNA - GAMG [nTPM]":"41.3","Cell RNA - HaCaT [nTPM]":"7.1","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"27.2","Cell RNA - HBF TERT88 [nTPM]":"40.7","Cell RNA - HDLM-2 [nTPM]":"9.3","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"12.4","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"36.4","Cell RNA - HHSteC [nTPM]":"36.3","Cell RNA - HL-60 [nTPM]":"31.2","Cell RNA - HMC-1 [nTPM]":"22.1","Cell RNA - HSkMC [nTPM]":"19.9","Cell RNA - hTCEpi [nTPM]":"4.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"44.3","Cell RNA - hTERT-HME1 [nTPM]":"53.7","Cell RNA - hTERT-RPE1 [nTPM]":"32.9","Cell RNA - HUVEC TERT2 [nTPM]":"41.0","Cell RNA - JURKAT [nTPM]":"4.4","Cell RNA - K-562 [nTPM]":"11.6","Cell RNA - Karpas-707 [nTPM]":"14.6","Cell RNA - LHCN-M2 [nTPM]":"47.5","Cell RNA - MCF7 [nTPM]":"19.8","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"47.7","Cell RNA - NTERA-2 [nTPM]":"54.2","Cell RNA - OE19 [nTPM]":"12.1","Cell RNA - PC-3 [nTPM]":"32.4","Cell RNA - REH [nTPM]":"86.6","Cell RNA - RH-30 [nTPM]":"36.0","Cell RNA - RPMI-8226 [nTPM]":"28.7","Cell RNA - RPTEC TERT1 [nTPM]":"23.0","Cell RNA - RT4 [nTPM]":"9.9","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"45.8","Cell RNA - SiHa [nTPM]":"8.7","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"178.3","Cell RNA - SuSa [nTPM]":"14.4","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"17.3","Cell RNA - TIME [nTPM]":"40.0","Cell RNA - U-138 MG [nTPM]":"15.0","Cell RNA - U-2 OS [nTPM]":"24.3","Cell RNA - U-2197 [nTPM]":"38.2","Cell RNA - U-251 MG [nTPM]":"70.5","Cell RNA - U-266\/70 [nTPM]":"11.1","Cell RNA - U-266\/84 [nTPM]":"49.9","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"45.8","Cell RNA - U-937 [nTPM]":"24.6","Cell RNA - WM-115 [nTPM]":"91.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"17.1","Brain RNA - basal ganglia [nTPM]":"22.4","Brain RNA - cerebellum [nTPM]":"17.7","Brain RNA - cerebral cortex [nTPM]":"24.4","Brain RNA - hippocampal formation [nTPM]":"17.8","Brain RNA - hypothalamus [nTPM]":"16.8","Brain RNA - medulla oblongata [nTPM]":"20.5","Brain RNA - midbrain [nTPM]":"17.1","Brain RNA - pons [nTPM]":"17.7","Brain RNA - spinal cord [nTPM]":"14.7","Brain RNA - thalamus [nTPM]":"17.2","Brain RNA - white matter [nTPM]":"19.6","Single Cell Type RNA - Adipocytes [nTPM]":"5.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"68.5","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"5.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"17.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"2.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.6","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"24.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.3","Single Cell Type RNA - Endothelial cells [nTPM]":"9.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.7","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"94.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.7","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"9.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"56.4","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.8","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"64.4","Single Cell Type RNA - Langerhans cells [nTPM]":"19.4","Single Cell Type RNA - Late spermatids [nTPM]":"49.0","Single Cell Type RNA - Leydig cells [nTPM]":"9.0","Single Cell Type RNA - Macrophages [nTPM]":"27.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"45.9","Single Cell Type RNA - monocytes [nTPM]":"2.1","Single Cell Type RNA - Muller glia cells [nTPM]":"60.4","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"169.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"47.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.4","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.6","Single Cell Type RNA - Spermatocytes [nTPM]":"16.9","Single Cell Type RNA - Spermatogonia [nTPM]":"14.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.8","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"3.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.5","Single Cell Type RNA - Urothelial cells [nTPM]":"2.7"},{"Gene":"EZH2","Gene synonym":["ENX-1","EZH1","KMT6","KMT6A"],"Ensembl":"ENSG00000106462","Gene description":"Enhancer of zeste 2 polycomb repressive complex 2 subunit","Uniprot":["Q15910"],"Chromosome":"7","Position":"148807383-148884321","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"47.9","lymphoid tissue":"43.0","testis":"27.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"109.3","Spermatocytes":"142.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009589","HPA029131"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB009589":null,"HPA029131":"AB_2672920"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.11e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.18e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.97e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.67e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.5","Tissue RNA - adrenal gland [nTPM]":"1.5","Tissue RNA - amygdala [nTPM]":"1.1","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"1.1","Tissue RNA - bone marrow [nTPM]":"47.9","Tissue RNA - breast [nTPM]":"2.7","Tissue RNA - cerebellum [nTPM]":"2.0","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"2.7","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"7.0","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"1.1","Tissue RNA - gallbladder [nTPM]":"1.9","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.1","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"3.3","Tissue RNA - lung [nTPM]":"2.3","Tissue RNA - lymph node [nTPM]":"22.1","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.2","Tissue RNA - ovary [nTPM]":"1.6","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"1.3","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"4.8","Tissue RNA - pons [nTPM]":"1.2","Tissue RNA - prostate [nTPM]":"1.3","Tissue RNA - rectum [nTPM]":"8.2","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"2.8","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"10.7","Tissue RNA - small intestine [nTPM]":"6.9","Tissue RNA - smooth muscle [nTPM]":"2.8","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"5.6","Tissue RNA - stomach 1 [nTPM]":"4.0","Tissue RNA - testis [nTPM]":"27.8","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"43.0","Tissue RNA - thyroid gland [nTPM]":"1.3","Tissue RNA - tongue [nTPM]":"1.9","Tissue RNA - tonsil [nTPM]":"21.1","Tissue RNA - urinary bladder [nTPM]":"3.5","Tissue RNA - vagina [nTPM]":"3.8","Tissue RNA - white matter [nTPM]":"1.2","Cell RNA - A-431 [nTPM]":"65.6","Cell RNA - A549 [nTPM]":"30.1","Cell RNA - AF22 [nTPM]":"99.7","Cell RNA - AN3-CA [nTPM]":"66.9","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"5.1","Cell RNA - BEWO [nTPM]":"54.6","Cell RNA - BJ [nTPM]":"49.7","Cell RNA - BJ hTERT+ [nTPM]":"19.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.2","Cell RNA - CACO-2 [nTPM]":"45.6","Cell RNA - CAPAN-2 [nTPM]":"73.2","Cell RNA - Daudi [nTPM]":"114.3","Cell RNA - EFO-21 [nTPM]":"23.5","Cell RNA - fHDF\/TERT166 [nTPM]":"18.7","Cell RNA - GAMG [nTPM]":"36.3","Cell RNA - HaCaT [nTPM]":"39.0","Cell RNA - HAP1 [nTPM]":"52.1","Cell RNA - HBEC3-KT [nTPM]":"17.1","Cell RNA - HBF TERT88 [nTPM]":"50.6","Cell RNA - HDLM-2 [nTPM]":"164.9","Cell RNA - HEK 293 [nTPM]":"51.8","Cell RNA - HEL [nTPM]":"48.9","Cell RNA - HeLa [nTPM]":"38.4","Cell RNA - Hep G2 [nTPM]":"35.5","Cell RNA - HHSteC [nTPM]":"8.0","Cell RNA - HL-60 [nTPM]":"110.1","Cell RNA - HMC-1 [nTPM]":"38.5","Cell RNA - HSkMC [nTPM]":"4.3","Cell RNA - hTCEpi [nTPM]":"9.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"29.9","Cell RNA - hTERT-HME1 [nTPM]":"15.9","Cell RNA - hTERT-RPE1 [nTPM]":"12.1","Cell RNA - HUVEC TERT2 [nTPM]":"24.0","Cell RNA - JURKAT [nTPM]":"108.9","Cell RNA - K-562 [nTPM]":"105.9","Cell RNA - Karpas-707 [nTPM]":"73.6","Cell RNA - LHCN-M2 [nTPM]":"36.2","Cell RNA - MCF7 [nTPM]":"74.0","Cell RNA - MOLT-4 [nTPM]":"215.7","Cell RNA - NB-4 [nTPM]":"91.7","Cell RNA - NTERA-2 [nTPM]":"79.6","Cell RNA - OE19 [nTPM]":"57.0","Cell RNA - PC-3 [nTPM]":"39.9","Cell RNA - REH [nTPM]":"131.3","Cell RNA - RH-30 [nTPM]":"56.0","Cell RNA - RPMI-8226 [nTPM]":"70.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.6","Cell RNA - RT4 [nTPM]":"31.0","Cell RNA - SCLC-21H [nTPM]":"95.1","Cell RNA - SH-SY5Y [nTPM]":"60.3","Cell RNA - SiHa [nTPM]":"62.3","Cell RNA - SK-BR-3 [nTPM]":"46.8","Cell RNA - SK-MEL-30 [nTPM]":"16.5","Cell RNA - SuSa [nTPM]":"25.3","Cell RNA - T-47d [nTPM]":"34.3","Cell RNA - THP-1 [nTPM]":"46.7","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"42.4","Cell RNA - U-2 OS [nTPM]":"19.8","Cell RNA - U-2197 [nTPM]":"85.2","Cell RNA - U-251 MG [nTPM]":"90.4","Cell RNA - U-266\/70 [nTPM]":"65.7","Cell RNA - U-266\/84 [nTPM]":"76.6","Cell RNA - U-698 [nTPM]":"115.3","Cell RNA - U-87 MG [nTPM]":"38.6","Cell RNA - U-937 [nTPM]":"74.2","Cell RNA - WM-115 [nTPM]":"84.9","Blood RNA - basophil [nTPM]":"0.4","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.1","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"0.9","Blood RNA - memory B-cell [nTPM]":"1.1","Blood RNA - memory CD4 T-cell [nTPM]":"2.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"3.8","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"7.2","Blood RNA - non-classical monocyte [nTPM]":"3.6","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"8.3","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"1.1","Brain RNA - basal ganglia [nTPM]":"1.1","Brain RNA - cerebellum [nTPM]":"2.0","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.1","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.2","Brain RNA - pons [nTPM]":"1.2","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"1.2","Single Cell Type RNA - Adipocytes [nTPM]":"14.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"14.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.8","Single Cell Type RNA - dendritic cells [nTPM]":"35.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.5","Single Cell Type RNA - Early spermatids [nTPM]":"109.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.0","Single Cell Type RNA - Endothelial cells [nTPM]":"9.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.0","Single Cell Type RNA - Erythroid cells [nTPM]":"57.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"32.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"15.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"24.2","Single Cell Type RNA - granulocytes [nTPM]":"21.6","Single Cell Type RNA - Granulosa cells [nTPM]":"45.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.3","Single Cell Type RNA - Hepatocytes [nTPM]":"2.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.9","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.0","Single Cell Type RNA - Langerhans cells [nTPM]":"33.6","Single Cell Type RNA - Late spermatids [nTPM]":"27.7","Single Cell Type RNA - Leydig cells [nTPM]":"3.1","Single Cell Type RNA - Macrophages [nTPM]":"19.1","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"14.9","Single Cell Type RNA - Muller glia cells [nTPM]":"2.6","Single Cell Type RNA - NK-cells [nTPM]":"12.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"12.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"37.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"24.1","Single Cell Type RNA - Spermatocytes [nTPM]":"142.2","Single Cell Type RNA - Spermatogonia [nTPM]":"58.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"35.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"30.5","Single Cell Type RNA - T-cells [nTPM]":"25.7","Single Cell Type RNA - Theca cells [nTPM]":"4.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.9"},{"Gene":"FAS","Gene synonym":["APO-1","APT1","CD95","FAS1","TNFRSF6"],"Ensembl":"ENSG00000026103","Gene description":"Fas cell surface death receptor","Uniprot":["P25445"],"Chromosome":"10","Position":"88990531-89017059","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","CD markers","Disease related genes","Human disease related genes","Metabolic proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Calmodulin-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"109.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"114.7"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"114.7","T-cells":"96.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"83.4","Karpas-707":"109.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA027444"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear bodies","Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":11900000,"Blood concentration - Conc. blood MS [pg\/L]":"420000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA027444":"AB_10601378"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.84e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"14.1","Tissue RNA - adrenal gland [nTPM]":"26.3","Tissue RNA - amygdala [nTPM]":"3.6","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"3.6","Tissue RNA - bone marrow [nTPM]":"20.8","Tissue RNA - breast [nTPM]":"10.9","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"12.7","Tissue RNA - choroid plexus [nTPM]":"2.8","Tissue RNA - colon [nTPM]":"16.4","Tissue RNA - duodenum [nTPM]":"7.0","Tissue RNA - endometrium 1 [nTPM]":"12.8","Tissue RNA - epididymis [nTPM]":"10.3","Tissue RNA - esophagus [nTPM]":"10.8","Tissue RNA - fallopian tube [nTPM]":"14.8","Tissue RNA - gallbladder [nTPM]":"15.7","Tissue RNA - heart muscle [nTPM]":"7.5","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"3.7","Tissue RNA - kidney [nTPM]":"7.2","Tissue RNA - liver [nTPM]":"23.3","Tissue RNA - lung [nTPM]":"21.7","Tissue RNA - lymph node [nTPM]":"18.9","Tissue RNA - medulla oblongata [nTPM]":"4.6","Tissue RNA - midbrain [nTPM]":"3.1","Tissue RNA - ovary [nTPM]":"20.1","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"2.7","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"10.4","Tissue RNA - pons [nTPM]":"4.0","Tissue RNA - prostate [nTPM]":"8.9","Tissue RNA - rectum [nTPM]":"23.3","Tissue RNA - retina [nTPM]":"3.3","Tissue RNA - salivary gland [nTPM]":"6.5","Tissue RNA - seminal vesicle [nTPM]":"9.3","Tissue RNA - skeletal muscle [nTPM]":"2.3","Tissue RNA - skin 1 [nTPM]":"9.4","Tissue RNA - small intestine [nTPM]":"9.2","Tissue RNA - smooth muscle [nTPM]":"15.0","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"11.2","Tissue RNA - stomach 1 [nTPM]":"4.4","Tissue RNA - testis [nTPM]":"2.6","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"14.4","Tissue RNA - thyroid gland [nTPM]":"7.3","Tissue RNA - tongue [nTPM]":"2.6","Tissue RNA - tonsil [nTPM]":"15.6","Tissue RNA - urinary bladder [nTPM]":"12.9","Tissue RNA - vagina [nTPM]":"10.2","Tissue RNA - white matter [nTPM]":"4.3","Cell RNA - A-431 [nTPM]":"22.7","Cell RNA - A549 [nTPM]":"8.2","Cell RNA - AF22 [nTPM]":"5.4","Cell RNA - AN3-CA [nTPM]":"13.9","Cell RNA - ASC diff [nTPM]":"37.0","Cell RNA - ASC TERT1 [nTPM]":"51.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"51.8","Cell RNA - BJ hTERT+ [nTPM]":"50.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.1","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"23.4","Cell RNA - Daudi [nTPM]":"4.7","Cell RNA - EFO-21 [nTPM]":"19.0","Cell RNA - fHDF\/TERT166 [nTPM]":"52.1","Cell RNA - GAMG [nTPM]":"9.6","Cell RNA - HaCaT [nTPM]":"4.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"44.8","Cell RNA - HBF TERT88 [nTPM]":"3.2","Cell RNA - HDLM-2 [nTPM]":"83.4","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"14.7","Cell RNA - HHSteC [nTPM]":"31.6","Cell RNA - HL-60 [nTPM]":"3.4","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"69.2","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.4","Cell RNA - hTERT-HME1 [nTPM]":"66.0","Cell RNA - hTERT-RPE1 [nTPM]":"24.5","Cell RNA - HUVEC TERT2 [nTPM]":"4.7","Cell RNA - JURKAT [nTPM]":"17.8","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"109.0","Cell RNA - LHCN-M2 [nTPM]":"44.0","Cell RNA - MCF7 [nTPM]":"1.4","Cell RNA - MOLT-4 [nTPM]":"6.4","Cell RNA - NB-4 [nTPM]":"3.4","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"1.4","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"5.0","Cell RNA - RPTEC TERT1 [nTPM]":"60.7","Cell RNA - RT4 [nTPM]":"7.3","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"7.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"13.9","Cell RNA - THP-1 [nTPM]":"1.0","Cell RNA - TIME [nTPM]":"9.5","Cell RNA - U-138 MG [nTPM]":"15.8","Cell RNA - U-2 OS [nTPM]":"9.0","Cell RNA - U-2197 [nTPM]":"15.2","Cell RNA - U-251 MG [nTPM]":"12.3","Cell RNA - U-266\/70 [nTPM]":"45.3","Cell RNA - U-266\/84 [nTPM]":"5.3","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"11.8","Cell RNA - U-937 [nTPM]":"10.2","Cell RNA - WM-115 [nTPM]":"4.5","Blood RNA - basophil [nTPM]":"43.1","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"30.9","Blood RNA - gdT-cell [nTPM]":"9.9","Blood RNA - intermediate monocyte [nTPM]":"12.3","Blood RNA - MAIT T-cell [nTPM]":"13.8","Blood RNA - memory B-cell [nTPM]":"7.5","Blood RNA - memory CD4 T-cell [nTPM]":"27.6","Blood RNA - memory CD8 T-cell [nTPM]":"19.6","Blood RNA - myeloid DC [nTPM]":"11.5","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.0","Blood RNA - neutrophil [nTPM]":"114.7","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"22.1","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"96.2","Blood RNA - total PBMC [nTPM]":"12.8","Brain RNA - amygdala [nTPM]":"3.6","Brain RNA - basal ganglia [nTPM]":"3.6","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"3.7","Brain RNA - medulla oblongata [nTPM]":"4.6","Brain RNA - midbrain [nTPM]":"3.1","Brain RNA - pons [nTPM]":"4.0","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"4.3","Single Cell Type RNA - Adipocytes [nTPM]":"10.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.8","Single Cell Type RNA - Astrocytes [nTPM]":"40.1","Single Cell Type RNA - B-cells [nTPM]":"12.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"45.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"109.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"53.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"27.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"11.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.3","Single Cell Type RNA - Endothelial cells [nTPM]":"8.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"35.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"4.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"19.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.5","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.4","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"7.0","Single Cell Type RNA - Langerhans cells [nTPM]":"31.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"17.7","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"14.5","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"6.5","Single Cell Type RNA - Paneth cells [nTPM]":"8.7","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"32.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"26.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"26.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"29.1","Single Cell Type RNA - Spermatocytes [nTPM]":"11.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"48.4","Single Cell Type RNA - Theca cells [nTPM]":"11.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.4","Single Cell Type RNA - Urothelial cells [nTPM]":"30.0"},{"Gene":"FEV","Gene synonym":["Pet-1"],"Ensembl":"ENSG00000163497","Gene description":"FEV transcription factor, ETS family member","Uniprot":["Q99581"],"Chromosome":"2","Position":"218981087-218985184","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"16","RNA tissue specific nTPM":{"brain":"70.8"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"32","RNA single cell type specific nTPM":{"Enteroendocrine cells":"744.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"10","RNA cancer specific FPKM":{"pancreatic cancer":"3.0","prostate cancer":"9.9","stomach cancer":"2.4"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"midbrain":"70.8","pons":"20.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"HMC-1":"35.5","SH-SY5Y":"43.8"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"midbrain":"1.9"},"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"4.8","pons":"2.7"},"Antibody":["HPA067679"],"Reliability (IH)":null,"Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 17: Intestinal endocrine cells - Hormone signaling","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA067679":"AB_2685884"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-1"},"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.85e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.96e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.1","Tissue RNA - adrenal gland [nTPM]":"2.3","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.6","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.2","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"6.2","Tissue RNA - midbrain [nTPM]":"70.8","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"20.1","Tissue RNA - prostate [nTPM]":"2.2","Tissue RNA - rectum [nTPM]":"1.8","Tissue RNA - retina [nTPM]":"0.4","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"2.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"3.1","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.1","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"7.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"35.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"2.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"5.1","Cell RNA - SH-SY5Y [nTPM]":"43.8","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.6","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"6.2","Brain RNA - midbrain [nTPM]":"70.8","Brain RNA - pons [nTPM]":"20.1","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"744.9","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"6.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"FGF3","Gene synonym":["HBGF-3","INT2"],"Ensembl":"ENSG00000186895","Gene description":"Fibroblast growth factor 3","Uniprot":["P11487"],"Chromosome":"11","Position":"69809968-69819416","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Differentiation"],"Molecular function":["Developmental protein","Growth factor","Mitogen"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"36","RNA tissue specific nTPM":{"brain":"3.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"endometrial cancer":"5.4"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebellum":"3.6"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"3.1"},"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA012692"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted in brain","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA012692":"AB_1848526"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.61e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"3.6","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.2","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"3.6","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"0.2","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FGFR1","Gene synonym":["BFGFR","CD331","CEK","FLG","FLT2","H2","H3","H4","H5","KAL2","N-SAM"],"Ensembl":"ENSG00000077782","Gene description":"Fibroblast growth factor receptor 1","Uniprot":["P11362"],"Chromosome":"8","Position":"38400215-38468834","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins","Transporters"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Heparin-binding","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Craniosynostosis","Disease variant","Dwarfism","FDA approved drug targets","Holoprosencephaly","Hypogonadotropic hypogonadism","Kallmann syndrome","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Fibroblasts":"176.7","Leydig cells":"192.0","Oligodendrocyte precursor cells":"166.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"508.7","BJ hTERT+":"278.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033614","HPA056402"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"78000000","Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB033614":"AB_783377","HPA056402":"AB_2683118"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.33e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.97e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.69e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.60e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-3"},"Tissue RNA - adipose tissue [nTPM]":"95.1","Tissue RNA - adrenal gland [nTPM]":"12.8","Tissue RNA - amygdala [nTPM]":"27.5","Tissue RNA - appendix [nTPM]":"15.9","Tissue RNA - basal ganglia [nTPM]":"24.6","Tissue RNA - bone marrow [nTPM]":"14.1","Tissue RNA - breast [nTPM]":"87.1","Tissue RNA - cerebellum [nTPM]":"48.8","Tissue RNA - cerebral cortex [nTPM]":"22.4","Tissue RNA - cervix [nTPM]":"79.8","Tissue RNA - choroid plexus [nTPM]":"37.2","Tissue RNA - colon [nTPM]":"97.2","Tissue RNA - duodenum [nTPM]":"8.8","Tissue RNA - endometrium 1 [nTPM]":"74.2","Tissue RNA - epididymis [nTPM]":"15.8","Tissue RNA - esophagus [nTPM]":"35.8","Tissue RNA - fallopian tube [nTPM]":"85.9","Tissue RNA - gallbladder [nTPM]":"57.1","Tissue RNA - heart muscle [nTPM]":"89.9","Tissue RNA - hippocampal formation [nTPM]":"30.9","Tissue RNA - hypothalamus [nTPM]":"28.8","Tissue RNA - kidney [nTPM]":"40.1","Tissue RNA - liver [nTPM]":"9.1","Tissue RNA - lung [nTPM]":"55.7","Tissue RNA - lymph node [nTPM]":"16.6","Tissue RNA - medulla oblongata [nTPM]":"35.9","Tissue RNA - midbrain [nTPM]":"37.3","Tissue RNA - ovary [nTPM]":"108.2","Tissue RNA - pancreas [nTPM]":"98.6","Tissue RNA - parathyroid gland [nTPM]":"20.4","Tissue RNA - pituitary gland [nTPM]":"57.1","Tissue RNA - placenta [nTPM]":"51.3","Tissue RNA - pons [nTPM]":"63.7","Tissue RNA - prostate [nTPM]":"60.5","Tissue RNA - rectum [nTPM]":"17.9","Tissue RNA - retina [nTPM]":"15.8","Tissue RNA - salivary gland [nTPM]":"31.4","Tissue RNA - seminal vesicle [nTPM]":"53.6","Tissue RNA - skeletal muscle [nTPM]":"24.8","Tissue RNA - skin 1 [nTPM]":"35.6","Tissue RNA - small intestine [nTPM]":"41.7","Tissue RNA - smooth muscle [nTPM]":"57.1","Tissue RNA - spinal cord [nTPM]":"30.3","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"40.4","Tissue RNA - testis [nTPM]":"20.4","Tissue RNA - thalamus [nTPM]":"33.4","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"33.7","Tissue RNA - tongue [nTPM]":"23.3","Tissue RNA - tonsil [nTPM]":"16.1","Tissue RNA - urinary bladder [nTPM]":"79.3","Tissue RNA - vagina [nTPM]":"63.9","Tissue RNA - white matter [nTPM]":"29.6","Cell RNA - A-431 [nTPM]":"12.9","Cell RNA - A549 [nTPM]":"42.0","Cell RNA - AF22 [nTPM]":"198.0","Cell RNA - AN3-CA [nTPM]":"508.7","Cell RNA - ASC diff [nTPM]":"120.1","Cell RNA - ASC TERT1 [nTPM]":"91.2","Cell RNA - BEWO [nTPM]":"142.9","Cell RNA - BJ [nTPM]":"136.7","Cell RNA - BJ hTERT+ [nTPM]":"278.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"90.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"95.8","Cell RNA - CACO-2 [nTPM]":"27.3","Cell RNA - CAPAN-2 [nTPM]":"6.5","Cell RNA - Daudi [nTPM]":"1.8","Cell RNA - EFO-21 [nTPM]":"38.3","Cell RNA - fHDF\/TERT166 [nTPM]":"127.7","Cell RNA - GAMG [nTPM]":"103.9","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"90.0","Cell RNA - HBEC3-KT [nTPM]":"6.8","Cell RNA - HBF TERT88 [nTPM]":"104.3","Cell RNA - HDLM-2 [nTPM]":"39.2","Cell RNA - HEK 293 [nTPM]":"24.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"7.7","Cell RNA - Hep G2 [nTPM]":"27.8","Cell RNA - HHSteC [nTPM]":"69.7","Cell RNA - HL-60 [nTPM]":"31.1","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"80.5","Cell RNA - hTCEpi [nTPM]":"0.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"70.9","Cell RNA - hTERT-HME1 [nTPM]":"13.3","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"86.9","Cell RNA - JURKAT [nTPM]":"6.0","Cell RNA - K-562 [nTPM]":"11.9","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"40.5","Cell RNA - MCF7 [nTPM]":"12.5","Cell RNA - MOLT-4 [nTPM]":"91.5","Cell RNA - NB-4 [nTPM]":"9.2","Cell RNA - NTERA-2 [nTPM]":"145.9","Cell RNA - OE19 [nTPM]":"1.6","Cell RNA - PC-3 [nTPM]":"21.6","Cell RNA - REH [nTPM]":"86.3","Cell RNA - RH-30 [nTPM]":"21.1","Cell RNA - RPMI-8226 [nTPM]":"0.4","Cell RNA - RPTEC TERT1 [nTPM]":"35.6","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"7.9","Cell RNA - SH-SY5Y [nTPM]":"19.4","Cell RNA - SiHa [nTPM]":"23.4","Cell RNA - SK-BR-3 [nTPM]":"1.0","Cell RNA - SK-MEL-30 [nTPM]":"5.1","Cell RNA - SuSa [nTPM]":"93.4","Cell RNA - T-47d [nTPM]":"9.3","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"51.4","Cell RNA - U-138 MG [nTPM]":"49.2","Cell RNA - U-2 OS [nTPM]":"28.9","Cell RNA - U-2197 [nTPM]":"149.6","Cell RNA - U-251 MG [nTPM]":"29.7","Cell RNA - U-266\/70 [nTPM]":"2.4","Cell RNA - U-266\/84 [nTPM]":"4.1","Cell RNA - U-698 [nTPM]":"0.5","Cell RNA - U-87 MG [nTPM]":"60.3","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"27.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.7","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.6","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"1.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"27.5","Brain RNA - basal ganglia [nTPM]":"24.6","Brain RNA - cerebellum [nTPM]":"48.8","Brain RNA - cerebral cortex [nTPM]":"22.4","Brain RNA - hippocampal formation [nTPM]":"30.9","Brain RNA - hypothalamus [nTPM]":"28.8","Brain RNA - medulla oblongata [nTPM]":"35.9","Brain RNA - midbrain [nTPM]":"37.3","Brain RNA - pons [nTPM]":"63.7","Brain RNA - spinal cord [nTPM]":"30.3","Brain RNA - thalamus [nTPM]":"33.4","Brain RNA - white matter [nTPM]":"29.6","Single Cell Type RNA - Adipocytes [nTPM]":"101.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"55.8","Single Cell Type RNA - B-cells [nTPM]":"1.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"31.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"95.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"37.0","Single Cell Type RNA - Bipolar cells [nTPM]":"4.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"77.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"52.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"5.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"27.3","Single Cell Type RNA - Early spermatids [nTPM]":"15.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.6","Single Cell Type RNA - Endothelial cells [nTPM]":"75.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"65.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"80.5","Single Cell Type RNA - Fibroblasts [nTPM]":"176.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"75.3","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"40.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"47.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.3","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"75.2","Single Cell Type RNA - Late spermatids [nTPM]":"15.0","Single Cell Type RNA - Leydig cells [nTPM]":"192.0","Single Cell Type RNA - Macrophages [nTPM]":"11.7","Single Cell Type RNA - Melanocytes [nTPM]":"33.8","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"1.7","Single Cell Type RNA - Muller glia cells [nTPM]":"88.1","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"166.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.6","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"99.6","Single Cell Type RNA - Plasma cells [nTPM]":"6.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"94.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"118.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"59.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"14.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.4","Single Cell Type RNA - T-cells [nTPM]":"14.1","Single Cell Type RNA - Theca cells [nTPM]":"2.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.7","Single Cell Type RNA - Urothelial cells [nTPM]":"11.7"},{"Gene":"FGFR2","Gene synonym":["BEK","CD332","CEK3","CFD1","ECT1","JWS","K-SAM","KGFR","TK14","TK25"],"Ensembl":"ENSG00000066468","Gene description":"Fibroblast growth factor receptor 2","Uniprot":["P21802"],"Chromosome":"10","Position":"121478332-121598458","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Apoptosis"],"Molecular function":["Heparin-binding","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Craniosynostosis","Disease variant","Ectodermal dysplasia","FDA approved drug targets","Lacrimo-auriculo-dento-digital syndrome","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"273.8","choroid plexus":"198.1"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Astrocytes":"228.2","Cholangiocytes":"213.1","Oligodendrocytes":"562.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"24","RNA blood cell specific nTPM":{"basophil":"13.2","eosinophil":"3.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"58","RNA blood lineage specific nTPM":{"granulocytes":"13.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AN3-CA":"189.0","BEWO":"60.9","CACO-2":"49.6","HaCaT":"55.6","HAP1":"63.7","NTERA-2":"57.8","T-47d":"49.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010886","HPA035305"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles","Cell Junctions"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1200000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 42: Oligodendrocytes - Myelin sheath organization","Subcellular main location":["Cell Junctions"],"Subcellular additional location":["Nucleoplasm","Vesicles"],"Antibody RRID":{"CAB010886":"AB_259379","HPA035305":"AB_10672862"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.79e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.32e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.93e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"5.7","Tissue RNA - adrenal gland [nTPM]":"21.3","Tissue RNA - amygdala [nTPM]":"103.9","Tissue RNA - appendix [nTPM]":"8.2","Tissue RNA - basal ganglia [nTPM]":"186.8","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"22.9","Tissue RNA - cerebellum [nTPM]":"178.9","Tissue RNA - cerebral cortex [nTPM]":"198.9","Tissue RNA - cervix [nTPM]":"19.7","Tissue RNA - choroid plexus [nTPM]":"198.1","Tissue RNA - colon [nTPM]":"44.8","Tissue RNA - duodenum [nTPM]":"10.4","Tissue RNA - endometrium 1 [nTPM]":"54.6","Tissue RNA - epididymis [nTPM]":"15.3","Tissue RNA - esophagus [nTPM]":"25.2","Tissue RNA - fallopian tube [nTPM]":"29.6","Tissue RNA - gallbladder [nTPM]":"31.3","Tissue RNA - heart muscle [nTPM]":"5.6","Tissue RNA - hippocampal formation [nTPM]":"109.9","Tissue RNA - hypothalamus [nTPM]":"124.7","Tissue RNA - kidney [nTPM]":"26.3","Tissue RNA - liver [nTPM]":"41.0","Tissue RNA - lung [nTPM]":"30.9","Tissue RNA - lymph node [nTPM]":"2.9","Tissue RNA - medulla oblongata [nTPM]":"250.9","Tissue RNA - midbrain [nTPM]":"185.9","Tissue RNA - ovary [nTPM]":"18.0","Tissue RNA - pancreas [nTPM]":"31.0","Tissue RNA - parathyroid gland [nTPM]":"61.0","Tissue RNA - pituitary gland [nTPM]":"6.8","Tissue RNA - placenta [nTPM]":"15.7","Tissue RNA - pons [nTPM]":"220.5","Tissue RNA - prostate [nTPM]":"27.4","Tissue RNA - rectum [nTPM]":"21.2","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"59.1","Tissue RNA - seminal vesicle [nTPM]":"54.6","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"109.3","Tissue RNA - small intestine [nTPM]":"12.2","Tissue RNA - smooth muscle [nTPM]":"43.6","Tissue RNA - spinal cord [nTPM]":"165.5","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"22.5","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"148.0","Tissue RNA - thymus [nTPM]":"10.1","Tissue RNA - thyroid gland [nTPM]":"54.6","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"9.1","Tissue RNA - urinary bladder [nTPM]":"16.6","Tissue RNA - vagina [nTPM]":"27.4","Tissue RNA - white matter [nTPM]":"273.8","Cell RNA - A-431 [nTPM]":"7.2","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"30.2","Cell RNA - AN3-CA [nTPM]":"189.0","Cell RNA - ASC diff [nTPM]":"0.1","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"60.9","Cell RNA - BJ [nTPM]":"0.4","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"49.6","Cell RNA - CAPAN-2 [nTPM]":"1.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"12.5","Cell RNA - fHDF\/TERT166 [nTPM]":"2.8","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"55.6","Cell RNA - HAP1 [nTPM]":"63.7","Cell RNA - HBEC3-KT [nTPM]":"13.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"12.7","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"11.7","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"26.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"11.7","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"57.8","Cell RNA - OE19 [nTPM]":"8.7","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"18.0","Cell RNA - RT4 [nTPM]":"15.8","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.5","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"33.4","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"36.6","Cell RNA - T-47d [nTPM]":"49.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"8.5","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.7","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.5","Blood RNA - basophil [nTPM]":"13.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"103.9","Brain RNA - basal ganglia [nTPM]":"186.8","Brain RNA - cerebellum [nTPM]":"178.9","Brain RNA - cerebral cortex [nTPM]":"198.9","Brain RNA - hippocampal formation [nTPM]":"109.9","Brain RNA - hypothalamus [nTPM]":"124.7","Brain RNA - medulla oblongata [nTPM]":"250.9","Brain RNA - midbrain [nTPM]":"185.9","Brain RNA - pons [nTPM]":"220.5","Brain RNA - spinal cord [nTPM]":"165.5","Brain RNA - thalamus [nTPM]":"148.0","Brain RNA - white matter [nTPM]":"273.8","Single Cell Type RNA - Adipocytes [nTPM]":"1.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.0","Single Cell Type RNA - Astrocytes [nTPM]":"228.2","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"40.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"34.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"58.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"25.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"213.1","Single Cell Type RNA - Club cells [nTPM]":"38.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.5","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"7.4","Single Cell Type RNA - Early spermatids [nTPM]":"4.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"9.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"31.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.8","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"4.4","Single Cell Type RNA - Late spermatids [nTPM]":"9.6","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.1","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"562.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.7","Single Cell Type RNA - Paneth cells [nTPM]":"3.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.7","Single Cell Type RNA - Spermatogonia [nTPM]":"9.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.0","Single Cell Type RNA - T-cells [nTPM]":"1.5","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.8","Single Cell Type RNA - Urothelial cells [nTPM]":"31.4"},{"Gene":"FGFR3","Gene synonym":["ACH","CD333","CEK2","JTK4"],"Ensembl":"ENSG00000068078","Gene description":"Fibroblast growth factor receptor 3","Uniprot":["P22607"],"Chromosome":"4","Position":"1793293-1808872","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Apoptosis"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Craniosynostosis","Deafness","Disease variant","Dwarfism","Ectodermal dysplasia","FDA approved drug targets","Lacrimo-auriculo-dento-digital syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"148.3","esophagus":"139.7","skin 1":"271.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"410.4","Basal keratinocytes":"103.8","Cholangiocytes":"91.5","Suprabasal keratinocytes":"88.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"48.2","HaCaT":"34.9","Hep G2":"80.6","NTERA-2":"36.1","RT4":"64.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004231","HPA067204"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":"Secreted - unknown location","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 64: Astrocytes - Nervous system maintenance","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"CAB004231":"AB_627596","HPA067204":"AB_2685804"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.77e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.22e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.6","Tissue RNA - adrenal gland [nTPM]":"1.6","Tissue RNA - amygdala [nTPM]":"118.0","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"140.6","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"115.6","Tissue RNA - cerebral cortex [nTPM]":"104.0","Tissue RNA - cervix [nTPM]":"23.7","Tissue RNA - choroid plexus [nTPM]":"37.4","Tissue RNA - colon [nTPM]":"12.2","Tissue RNA - duodenum [nTPM]":"19.5","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"2.8","Tissue RNA - esophagus [nTPM]":"139.7","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"7.9","Tissue RNA - heart muscle [nTPM]":"4.8","Tissue RNA - hippocampal formation [nTPM]":"100.8","Tissue RNA - hypothalamus [nTPM]":"107.6","Tissue RNA - kidney [nTPM]":"39.3","Tissue RNA - liver [nTPM]":"40.7","Tissue RNA - lung [nTPM]":"7.4","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"144.7","Tissue RNA - midbrain [nTPM]":"129.2","Tissue RNA - ovary [nTPM]":"0.5","Tissue RNA - pancreas [nTPM]":"76.4","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"16.1","Tissue RNA - placenta [nTPM]":"9.3","Tissue RNA - pons [nTPM]":"109.8","Tissue RNA - prostate [nTPM]":"13.8","Tissue RNA - rectum [nTPM]":"5.2","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"20.2","Tissue RNA - seminal vesicle [nTPM]":"15.0","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"271.5","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"0.4","Tissue RNA - spinal cord [nTPM]":"108.9","Tissue RNA - spleen [nTPM]":"4.0","Tissue RNA - stomach 1 [nTPM]":"7.8","Tissue RNA - testis [nTPM]":"17.6","Tissue RNA - thalamus [nTPM]":"148.3","Tissue RNA - thymus [nTPM]":"1.7","Tissue RNA - thyroid gland [nTPM]":"1.5","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"11.1","Tissue RNA - urinary bladder [nTPM]":"23.1","Tissue RNA - vagina [nTPM]":"60.9","Tissue RNA - white matter [nTPM]":"81.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"19.5","Cell RNA - AN3-CA [nTPM]":"5.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"22.1","Cell RNA - BJ [nTPM]":"2.4","Cell RNA - BJ hTERT+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"48.2","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"17.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"34.9","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"19.3","Cell RNA - HEL [nTPM]":"14.2","Cell RNA - HeLa [nTPM]":"3.9","Cell RNA - Hep G2 [nTPM]":"80.6","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"10.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"2.3","Cell RNA - K-562 [nTPM]":"16.7","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"23.9","Cell RNA - MOLT-4 [nTPM]":"0.8","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"36.1","Cell RNA - OE19 [nTPM]":"19.5","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"1.0","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"64.1","Cell RNA - SCLC-21H [nTPM]":"5.7","Cell RNA - SH-SY5Y [nTPM]":"1.6","Cell RNA - SiHa [nTPM]":"1.9","Cell RNA - SK-BR-3 [nTPM]":"4.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"22.2","Cell RNA - T-47d [nTPM]":"20.4","Cell RNA - THP-1 [nTPM]":"2.5","Cell RNA - TIME [nTPM]":"1.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"2.1","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"1.6","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.2","Cell RNA - U-937 [nTPM]":"1.7","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"118.0","Brain RNA - basal ganglia [nTPM]":"140.6","Brain RNA - cerebellum [nTPM]":"115.6","Brain RNA - cerebral cortex [nTPM]":"104.0","Brain RNA - hippocampal formation [nTPM]":"100.8","Brain RNA - hypothalamus [nTPM]":"107.6","Brain RNA - medulla oblongata [nTPM]":"144.7","Brain RNA - midbrain [nTPM]":"129.2","Brain RNA - pons [nTPM]":"109.8","Brain RNA - spinal cord [nTPM]":"108.9","Brain RNA - thalamus [nTPM]":"148.3","Brain RNA - white matter [nTPM]":"81.2","Single Cell Type RNA - Adipocytes [nTPM]":"2.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.5","Single Cell Type RNA - Astrocytes [nTPM]":"410.4","Single Cell Type RNA - B-cells [nTPM]":"1.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"103.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"91.5","Single Cell Type RNA - Club cells [nTPM]":"37.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.0","Single Cell Type RNA - Early spermatids [nTPM]":"7.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.7","Single Cell Type RNA - Endothelial cells [nTPM]":"3.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.0","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"3.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.1","Single Cell Type RNA - Hepatocytes [nTPM]":"30.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"6.5","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"34.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"18.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"25.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"55.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"88.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.7","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.0","Single Cell Type RNA - Urothelial cells [nTPM]":"12.8"},{"Gene":"FH","Gene synonym":[],"Ensembl":"ENSG00000091483","Gene description":"Fumarate hydratase","Uniprot":["P07954"],"Chromosome":"1","Position":"241497603-241519755","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Tricarboxylic acid cycle"],"Molecular function":["Lyase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"276.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"173.5","Early spermatids":"226.0","Syncytiotrophoblasts":"166.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017785","HPA025770","HPA025948","HPA027341"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"CAB017785":null,"HPA025770":"AB_10599603","HPA025948":"AB_10602177","HPA027341":"AB_10601222"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.76e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.4","Tissue RNA - adrenal gland [nTPM]":"75.2","Tissue RNA - amygdala [nTPM]":"30.4","Tissue RNA - appendix [nTPM]":"31.0","Tissue RNA - basal ganglia [nTPM]":"33.3","Tissue RNA - bone marrow [nTPM]":"31.4","Tissue RNA - breast [nTPM]":"37.3","Tissue RNA - cerebellum [nTPM]":"33.5","Tissue RNA - cerebral cortex [nTPM]":"42.0","Tissue RNA - cervix [nTPM]":"28.9","Tissue RNA - choroid plexus [nTPM]":"43.9","Tissue RNA - colon [nTPM]":"66.8","Tissue RNA - duodenum [nTPM]":"68.2","Tissue RNA - endometrium 1 [nTPM]":"36.9","Tissue RNA - epididymis [nTPM]":"26.1","Tissue RNA - esophagus [nTPM]":"51.1","Tissue RNA - fallopian tube [nTPM]":"27.9","Tissue RNA - gallbladder [nTPM]":"23.7","Tissue RNA - heart muscle [nTPM]":"179.0","Tissue RNA - hippocampal formation [nTPM]":"33.9","Tissue RNA - hypothalamus [nTPM]":"33.1","Tissue RNA - kidney [nTPM]":"101.8","Tissue RNA - liver [nTPM]":"276.4","Tissue RNA - lung [nTPM]":"26.4","Tissue RNA - lymph node [nTPM]":"30.0","Tissue RNA - medulla oblongata [nTPM]":"31.8","Tissue RNA - midbrain [nTPM]":"31.0","Tissue RNA - ovary [nTPM]":"24.9","Tissue RNA - pancreas [nTPM]":"38.1","Tissue RNA - parathyroid gland [nTPM]":"95.0","Tissue RNA - pituitary gland [nTPM]":"31.1","Tissue RNA - placenta [nTPM]":"32.1","Tissue RNA - pons [nTPM]":"32.1","Tissue RNA - prostate [nTPM]":"33.5","Tissue RNA - rectum [nTPM]":"69.0","Tissue RNA - retina [nTPM]":"58.8","Tissue RNA - salivary gland [nTPM]":"42.0","Tissue RNA - seminal vesicle [nTPM]":"38.4","Tissue RNA - skeletal muscle [nTPM]":"213.4","Tissue RNA - skin 1 [nTPM]":"40.3","Tissue RNA - small intestine [nTPM]":"59.1","Tissue RNA - smooth muscle [nTPM]":"42.0","Tissue RNA - spinal cord [nTPM]":"32.4","Tissue RNA - spleen [nTPM]":"30.1","Tissue RNA - stomach 1 [nTPM]":"53.6","Tissue RNA - testis [nTPM]":"44.4","Tissue RNA - thalamus [nTPM]":"32.7","Tissue RNA - thymus [nTPM]":"31.3","Tissue RNA - thyroid gland [nTPM]":"34.6","Tissue RNA - tongue [nTPM]":"229.3","Tissue RNA - tonsil [nTPM]":"40.4","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"33.7","Tissue RNA - white matter [nTPM]":"33.0","Cell RNA - A-431 [nTPM]":"129.2","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"97.9","Cell RNA - AN3-CA [nTPM]":"89.0","Cell RNA - ASC diff [nTPM]":"93.9","Cell RNA - ASC TERT1 [nTPM]":"110.0","Cell RNA - BEWO [nTPM]":"154.9","Cell RNA - BJ [nTPM]":"155.7","Cell RNA - BJ hTERT+ [nTPM]":"121.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"171.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.1","Cell RNA - CACO-2 [nTPM]":"152.2","Cell RNA - CAPAN-2 [nTPM]":"78.0","Cell RNA - Daudi [nTPM]":"81.1","Cell RNA - EFO-21 [nTPM]":"100.3","Cell RNA - fHDF\/TERT166 [nTPM]":"119.9","Cell RNA - GAMG [nTPM]":"75.0","Cell RNA - HaCaT [nTPM]":"178.4","Cell RNA - HAP1 [nTPM]":"151.7","Cell RNA - HBEC3-KT [nTPM]":"115.8","Cell RNA - HBF TERT88 [nTPM]":"148.4","Cell RNA - HDLM-2 [nTPM]":"93.5","Cell RNA - HEK 293 [nTPM]":"48.9","Cell RNA - HEL [nTPM]":"76.3","Cell RNA - HeLa [nTPM]":"102.2","Cell RNA - Hep G2 [nTPM]":"131.4","Cell RNA - HHSteC [nTPM]":"84.1","Cell RNA - HL-60 [nTPM]":"180.2","Cell RNA - HMC-1 [nTPM]":"66.7","Cell RNA - HSkMC [nTPM]":"80.2","Cell RNA - hTCEpi [nTPM]":"70.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"96.6","Cell RNA - hTERT-HME1 [nTPM]":"108.0","Cell RNA - hTERT-RPE1 [nTPM]":"60.2","Cell RNA - HUVEC TERT2 [nTPM]":"107.2","Cell RNA - JURKAT [nTPM]":"175.8","Cell RNA - K-562 [nTPM]":"236.3","Cell RNA - Karpas-707 [nTPM]":"101.7","Cell RNA - LHCN-M2 [nTPM]":"126.9","Cell RNA - MCF7 [nTPM]":"64.3","Cell RNA - MOLT-4 [nTPM]":"156.6","Cell RNA - NB-4 [nTPM]":"120.1","Cell RNA - NTERA-2 [nTPM]":"104.5","Cell RNA - OE19 [nTPM]":"186.2","Cell RNA - PC-3 [nTPM]":"223.6","Cell RNA - REH [nTPM]":"127.4","Cell RNA - RH-30 [nTPM]":"107.2","Cell RNA - RPMI-8226 [nTPM]":"365.7","Cell RNA - RPTEC TERT1 [nTPM]":"167.4","Cell RNA - RT4 [nTPM]":"107.6","Cell RNA - SCLC-21H [nTPM]":"125.4","Cell RNA - SH-SY5Y [nTPM]":"108.4","Cell RNA - SiHa [nTPM]":"131.1","Cell RNA - SK-BR-3 [nTPM]":"153.3","Cell RNA - SK-MEL-30 [nTPM]":"104.0","Cell RNA - SuSa [nTPM]":"67.2","Cell RNA - T-47d [nTPM]":"117.1","Cell RNA - THP-1 [nTPM]":"120.9","Cell RNA - TIME [nTPM]":"106.5","Cell RNA - U-138 MG [nTPM]":"76.6","Cell RNA - U-2 OS [nTPM]":"98.9","Cell RNA - U-2197 [nTPM]":"137.0","Cell RNA - U-251 MG [nTPM]":"264.0","Cell RNA - U-266\/70 [nTPM]":"90.3","Cell RNA - U-266\/84 [nTPM]":"103.7","Cell RNA - U-698 [nTPM]":"97.3","Cell RNA - U-87 MG [nTPM]":"85.7","Cell RNA - U-937 [nTPM]":"203.5","Cell RNA - WM-115 [nTPM]":"112.6","Blood RNA - basophil [nTPM]":"11.9","Blood RNA - classical monocyte [nTPM]":"22.8","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"16.1","Blood RNA - intermediate monocyte [nTPM]":"33.3","Blood RNA - MAIT T-cell [nTPM]":"21.0","Blood RNA - memory B-cell [nTPM]":"27.2","Blood RNA - memory CD4 T-cell [nTPM]":"18.8","Blood RNA - memory CD8 T-cell [nTPM]":"15.1","Blood RNA - myeloid DC [nTPM]":"46.7","Blood RNA - naive B-cell [nTPM]":"25.1","Blood RNA - naive CD4 T-cell [nTPM]":"22.3","Blood RNA - naive CD8 T-cell [nTPM]":"21.1","Blood RNA - neutrophil [nTPM]":"1.3","Blood RNA - NK-cell [nTPM]":"18.3","Blood RNA - non-classical monocyte [nTPM]":"29.1","Blood RNA - plasmacytoid DC [nTPM]":"23.1","Blood RNA - T-reg [nTPM]":"23.8","Blood RNA - total PBMC [nTPM]":"16.7","Brain RNA - amygdala [nTPM]":"30.4","Brain RNA - basal ganglia [nTPM]":"33.3","Brain RNA - cerebellum [nTPM]":"33.5","Brain RNA - cerebral cortex [nTPM]":"42.0","Brain RNA - hippocampal formation [nTPM]":"33.9","Brain RNA - hypothalamus [nTPM]":"33.1","Brain RNA - medulla oblongata [nTPM]":"31.8","Brain RNA - midbrain [nTPM]":"31.0","Brain RNA - pons [nTPM]":"32.1","Brain RNA - spinal cord [nTPM]":"32.4","Brain RNA - thalamus [nTPM]":"32.7","Brain RNA - white matter [nTPM]":"33.0","Single Cell Type RNA - Adipocytes [nTPM]":"17.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"30.2","Single Cell Type RNA - Astrocytes [nTPM]":"9.4","Single Cell Type RNA - B-cells [nTPM]":"25.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"20.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"17.1","Single Cell Type RNA - Bipolar cells [nTPM]":"24.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"173.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"40.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.6","Single Cell Type RNA - dendritic cells [nTPM]":"13.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"78.2","Single Cell Type RNA - Ductal cells [nTPM]":"60.4","Single Cell Type RNA - Early spermatids [nTPM]":"226.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.5","Single Cell Type RNA - Endothelial cells [nTPM]":"18.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.0","Single Cell Type RNA - Erythroid cells [nTPM]":"37.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.7","Single Cell Type RNA - Fibroblasts [nTPM]":"25.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"26.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.4","Single Cell Type RNA - granulocytes [nTPM]":"19.0","Single Cell Type RNA - Granulosa cells [nTPM]":"24.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"80.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"50.7","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.6","Single Cell Type RNA - Ionocytes [nTPM]":"48.8","Single Cell Type RNA - Kupffer cells [nTPM]":"18.5","Single Cell Type RNA - Langerhans cells [nTPM]":"14.4","Single Cell Type RNA - Late spermatids [nTPM]":"37.4","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"23.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"27.9","Single Cell Type RNA - Muller glia cells [nTPM]":"35.0","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.4","Single Cell Type RNA - Paneth cells [nTPM]":"35.7","Single Cell Type RNA - Peritubular cells [nTPM]":"26.7","Single Cell Type RNA - Plasma cells [nTPM]":"41.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"66.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"29.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"39.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"67.9","Single Cell Type RNA - Spermatocytes [nTPM]":"84.7","Single Cell Type RNA - Spermatogonia [nTPM]":"47.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"32.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"166.1","Single Cell Type RNA - T-cells [nTPM]":"14.9","Single Cell Type RNA - Theca cells [nTPM]":"48.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"74.2","Single Cell Type RNA - Urothelial cells [nTPM]":"22.8"},{"Gene":"FHIT","Gene synonym":["AP3Aase","FRA3B"],"Ensembl":"ENSG00000189283","Gene description":"Fragile histidine triad diadenosine triphosphatase","Uniprot":["P49789"],"Chromosome":"3","Position":"59747277-61251459","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation"],"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"choroid plexus":"94.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"609.8","Inhibitory neurons":"450.5","Microglial cells":"337.3","Oligodendrocyte precursor cells":"1086.7","Oligodendrocytes":"1111.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"naive CD4 T-cell":"87.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"12","RNA blood lineage specific nTPM":{"T-cells":"87.6"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"17.5","U-266\/70":"34.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002684","HPA018840","HPA018909"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"12000","Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 88: Choroid plexus - Transmembrane transport","Cell line expression cluster":"Cluster 29: U-266 - Adaptive immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nucleoli fibrillar center","Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002684":null,"HPA018840":"AB_1848538","HPA018909":"AB_1848537"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.49e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.6","Tissue RNA - adrenal gland [nTPM]":"24.4","Tissue RNA - amygdala [nTPM]":"13.7","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"18.3","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"9.0","Tissue RNA - cerebellum [nTPM]":"13.0","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"5.4","Tissue RNA - choroid plexus [nTPM]":"94.0","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"3.5","Tissue RNA - epididymis [nTPM]":"6.9","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"6.6","Tissue RNA - gallbladder [nTPM]":"9.8","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"19.7","Tissue RNA - hypothalamus [nTPM]":"16.4","Tissue RNA - kidney [nTPM]":"24.9","Tissue RNA - liver [nTPM]":"9.6","Tissue RNA - lung [nTPM]":"4.7","Tissue RNA - lymph node [nTPM]":"7.6","Tissue RNA - medulla oblongata [nTPM]":"18.9","Tissue RNA - midbrain [nTPM]":"17.0","Tissue RNA - ovary [nTPM]":"6.8","Tissue RNA - pancreas [nTPM]":"13.0","Tissue RNA - parathyroid gland [nTPM]":"18.1","Tissue RNA - pituitary gland [nTPM]":"7.9","Tissue RNA - placenta [nTPM]":"3.0","Tissue RNA - pons [nTPM]":"18.9","Tissue RNA - prostate [nTPM]":"5.3","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"7.6","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"4.7","Tissue RNA - skeletal muscle [nTPM]":"10.6","Tissue RNA - skin 1 [nTPM]":"8.1","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"4.7","Tissue RNA - spinal cord [nTPM]":"15.0","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"8.6","Tissue RNA - testis [nTPM]":"5.5","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"12.1","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"4.2","Tissue RNA - white matter [nTPM]":"19.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.6","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"2.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.7","Cell RNA - CAPAN-2 [nTPM]":"4.2","Cell RNA - Daudi [nTPM]":"4.0","Cell RNA - EFO-21 [nTPM]":"0.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"3.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"12.7","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"2.2","Cell RNA - HEK 293 [nTPM]":"5.0","Cell RNA - HEL [nTPM]":"3.3","Cell RNA - HeLa [nTPM]":"2.0","Cell RNA - Hep G2 [nTPM]":"6.4","Cell RNA - HHSteC [nTPM]":"3.3","Cell RNA - HL-60 [nTPM]":"8.7","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"9.1","Cell RNA - hTCEpi [nTPM]":"5.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"3.7","Cell RNA - K-562 [nTPM]":"2.5","Cell RNA - Karpas-707 [nTPM]":"11.9","Cell RNA - LHCN-M2 [nTPM]":"0.2","Cell RNA - MCF7 [nTPM]":"3.6","Cell RNA - MOLT-4 [nTPM]":"15.2","Cell RNA - NB-4 [nTPM]":"6.7","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"0.9","Cell RNA - REH [nTPM]":"11.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"17.5","Cell RNA - RPTEC TERT1 [nTPM]":"15.3","Cell RNA - RT4 [nTPM]":"2.0","Cell RNA - SCLC-21H [nTPM]":"2.9","Cell RNA - SH-SY5Y [nTPM]":"4.3","Cell RNA - SiHa [nTPM]":"1.5","Cell RNA - SK-BR-3 [nTPM]":"9.9","Cell RNA - SK-MEL-30 [nTPM]":"10.1","Cell RNA - SuSa [nTPM]":"5.3","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.2","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.7","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"34.6","Cell RNA - U-266\/84 [nTPM]":"11.3","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.9","Blood RNA - basophil [nTPM]":"6.8","Blood RNA - classical monocyte [nTPM]":"4.6","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"2.2","Blood RNA - intermediate monocyte [nTPM]":"2.9","Blood RNA - MAIT T-cell [nTPM]":"1.4","Blood RNA - memory B-cell [nTPM]":"4.1","Blood RNA - memory CD4 T-cell [nTPM]":"17.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.8","Blood RNA - myeloid DC [nTPM]":"5.7","Blood RNA - naive B-cell [nTPM]":"3.1","Blood RNA - naive CD4 T-cell [nTPM]":"87.6","Blood RNA - naive CD8 T-cell [nTPM]":"15.6","Blood RNA - neutrophil [nTPM]":"0.8","Blood RNA - NK-cell [nTPM]":"7.2","Blood RNA - non-classical monocyte [nTPM]":"1.3","Blood RNA - plasmacytoid DC [nTPM]":"5.8","Blood RNA - T-reg [nTPM]":"20.5","Blood RNA - total PBMC [nTPM]":"11.9","Brain RNA - amygdala [nTPM]":"13.7","Brain RNA - basal ganglia [nTPM]":"18.3","Brain RNA - cerebellum [nTPM]":"13.0","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"19.7","Brain RNA - hypothalamus [nTPM]":"16.4","Brain RNA - medulla oblongata [nTPM]":"18.9","Brain RNA - midbrain [nTPM]":"17.0","Brain RNA - pons [nTPM]":"18.9","Brain RNA - spinal cord [nTPM]":"15.0","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"19.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"609.8","Single Cell Type RNA - B-cells [nTPM]":"19.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"46.7","Single Cell Type RNA - Bipolar cells [nTPM]":"12.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"41.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"17.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"58.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"42.0","Single Cell Type RNA - dendritic cells [nTPM]":"12.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"78.2","Single Cell Type RNA - Ductal cells [nTPM]":"19.1","Single Cell Type RNA - Early spermatids [nTPM]":"45.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"7.9","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.7","Single Cell Type RNA - Erythroid cells [nTPM]":"17.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"276.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.5","Single Cell Type RNA - Fibroblasts [nTPM]":"10.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.0","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"25.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"14.6","Single Cell Type RNA - Hepatocytes [nTPM]":"23.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.9","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"450.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"10.2","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"163.0","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"12.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"337.3","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"19.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1086.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1111.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.7","Single Cell Type RNA - Paneth cells [nTPM]":"15.0","Single Cell Type RNA - Peritubular cells [nTPM]":"9.8","Single Cell Type RNA - Plasma cells [nTPM]":"23.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"126.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"6.2","Single Cell Type RNA - Spermatocytes [nTPM]":"19.1","Single Cell Type RNA - Spermatogonia [nTPM]":"7.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"32.7","Single Cell Type RNA - T-cells [nTPM]":"11.5","Single Cell Type RNA - Theca cells [nTPM]":"23.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"18.8"},{"Gene":"FLCN","Gene synonym":["BHD","DENND8B","MGC17998","MGC23445"],"Ensembl":"ENSG00000154803","Gene description":"Folliculin","Uniprot":["Q8NFG4"],"Chromosome":"17","Position":"17212212-17237188","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cone photoreceptor cells":"79.2","Erythroid cells":"81.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB015158","HPA028760"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB015158":"AB_2231645","HPA028760":"AB_10601323"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.49e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Tissue RNA - adipose tissue [nTPM]":"21.8","Tissue RNA - adrenal gland [nTPM]":"19.0","Tissue RNA - amygdala [nTPM]":"19.0","Tissue RNA - appendix [nTPM]":"10.7","Tissue RNA - basal ganglia [nTPM]":"25.9","Tissue RNA - bone marrow [nTPM]":"17.7","Tissue RNA - breast [nTPM]":"18.9","Tissue RNA - cerebellum [nTPM]":"27.3","Tissue RNA - cerebral cortex [nTPM]":"31.6","Tissue RNA - cervix [nTPM]":"42.5","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"43.7","Tissue RNA - duodenum [nTPM]":"23.3","Tissue RNA - endometrium 1 [nTPM]":"37.0","Tissue RNA - epididymis [nTPM]":"14.5","Tissue RNA - esophagus [nTPM]":"13.8","Tissue RNA - fallopian tube [nTPM]":"25.2","Tissue RNA - gallbladder [nTPM]":"17.0","Tissue RNA - heart muscle [nTPM]":"29.2","Tissue RNA - hippocampal formation [nTPM]":"31.9","Tissue RNA - hypothalamus [nTPM]":"14.0","Tissue RNA - kidney [nTPM]":"15.3","Tissue RNA - liver [nTPM]":"28.9","Tissue RNA - lung [nTPM]":"26.8","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"21.3","Tissue RNA - midbrain [nTPM]":"15.2","Tissue RNA - ovary [nTPM]":"35.3","Tissue RNA - pancreas [nTPM]":"15.2","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"28.6","Tissue RNA - placenta [nTPM]":"13.1","Tissue RNA - pons [nTPM]":"22.0","Tissue RNA - prostate [nTPM]":"27.1","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"7.2","Tissue RNA - salivary gland [nTPM]":"16.4","Tissue RNA - seminal vesicle [nTPM]":"13.7","Tissue RNA - skeletal muscle [nTPM]":"42.7","Tissue RNA - skin 1 [nTPM]":"19.3","Tissue RNA - small intestine [nTPM]":"26.8","Tissue RNA - smooth muscle [nTPM]":"14.5","Tissue RNA - spinal cord [nTPM]":"14.0","Tissue RNA - spleen [nTPM]":"29.2","Tissue RNA - stomach 1 [nTPM]":"22.4","Tissue RNA - testis [nTPM]":"21.0","Tissue RNA - thalamus [nTPM]":"19.3","Tissue RNA - thymus [nTPM]":"8.6","Tissue RNA - thyroid gland [nTPM]":"23.8","Tissue RNA - tongue [nTPM]":"18.4","Tissue RNA - tonsil [nTPM]":"8.0","Tissue RNA - urinary bladder [nTPM]":"28.2","Tissue RNA - vagina [nTPM]":"25.5","Tissue RNA - white matter [nTPM]":"28.3","Cell RNA - A-431 [nTPM]":"12.0","Cell RNA - A549 [nTPM]":"30.4","Cell RNA - AF22 [nTPM]":"11.5","Cell RNA - AN3-CA [nTPM]":"14.9","Cell RNA - ASC diff [nTPM]":"36.4","Cell RNA - ASC TERT1 [nTPM]":"20.6","Cell RNA - BEWO [nTPM]":"15.8","Cell RNA - BJ [nTPM]":"11.8","Cell RNA - BJ hTERT+ [nTPM]":"19.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.3","Cell RNA - CACO-2 [nTPM]":"24.3","Cell RNA - CAPAN-2 [nTPM]":"10.4","Cell RNA - Daudi [nTPM]":"6.3","Cell RNA - EFO-21 [nTPM]":"13.8","Cell RNA - fHDF\/TERT166 [nTPM]":"14.0","Cell RNA - GAMG [nTPM]":"40.2","Cell RNA - HaCaT [nTPM]":"14.4","Cell RNA - HAP1 [nTPM]":"14.0","Cell RNA - HBEC3-KT [nTPM]":"7.3","Cell RNA - HBF TERT88 [nTPM]":"9.3","Cell RNA - HDLM-2 [nTPM]":"10.9","Cell RNA - HEK 293 [nTPM]":"12.2","Cell RNA - HEL [nTPM]":"12.4","Cell RNA - HeLa [nTPM]":"9.1","Cell RNA - Hep G2 [nTPM]":"13.9","Cell RNA - HHSteC [nTPM]":"33.6","Cell RNA - HL-60 [nTPM]":"4.9","Cell RNA - HMC-1 [nTPM]":"33.5","Cell RNA - HSkMC [nTPM]":"30.3","Cell RNA - hTCEpi [nTPM]":"24.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"27.6","Cell RNA - hTERT-HME1 [nTPM]":"20.8","Cell RNA - hTERT-RPE1 [nTPM]":"16.4","Cell RNA - HUVEC TERT2 [nTPM]":"14.8","Cell RNA - JURKAT [nTPM]":"9.2","Cell RNA - K-562 [nTPM]":"17.7","Cell RNA - Karpas-707 [nTPM]":"16.4","Cell RNA - LHCN-M2 [nTPM]":"17.6","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"8.3","Cell RNA - NB-4 [nTPM]":"8.4","Cell RNA - NTERA-2 [nTPM]":"11.2","Cell RNA - OE19 [nTPM]":"17.8","Cell RNA - PC-3 [nTPM]":"8.1","Cell RNA - REH [nTPM]":"16.9","Cell RNA - RH-30 [nTPM]":"52.7","Cell RNA - RPMI-8226 [nTPM]":"7.3","Cell RNA - RPTEC TERT1 [nTPM]":"11.0","Cell RNA - RT4 [nTPM]":"14.1","Cell RNA - SCLC-21H [nTPM]":"13.6","Cell RNA - SH-SY5Y [nTPM]":"8.8","Cell RNA - SiHa [nTPM]":"11.6","Cell RNA - SK-BR-3 [nTPM]":"7.5","Cell RNA - SK-MEL-30 [nTPM]":"19.3","Cell RNA - SuSa [nTPM]":"70.7","Cell RNA - T-47d [nTPM]":"11.1","Cell RNA - THP-1 [nTPM]":"8.8","Cell RNA - TIME [nTPM]":"15.7","Cell RNA - U-138 MG [nTPM]":"40.6","Cell RNA - U-2 OS [nTPM]":"16.6","Cell RNA - U-2197 [nTPM]":"56.5","Cell RNA - U-251 MG [nTPM]":"14.1","Cell RNA - U-266\/70 [nTPM]":"7.7","Cell RNA - U-266\/84 [nTPM]":"7.4","Cell RNA - U-698 [nTPM]":"5.7","Cell RNA - U-87 MG [nTPM]":"26.0","Cell RNA - U-937 [nTPM]":"10.8","Cell RNA - WM-115 [nTPM]":"16.6","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"2.8","Blood RNA - eosinophil [nTPM]":"1.6","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"3.6","Blood RNA - memory CD4 T-cell [nTPM]":"1.9","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"3.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"6.0","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"19.0","Brain RNA - basal ganglia [nTPM]":"25.9","Brain RNA - cerebellum [nTPM]":"27.3","Brain RNA - cerebral cortex [nTPM]":"31.6","Brain RNA - hippocampal formation [nTPM]":"31.9","Brain RNA - hypothalamus [nTPM]":"14.0","Brain RNA - medulla oblongata [nTPM]":"21.3","Brain RNA - midbrain [nTPM]":"15.2","Brain RNA - pons [nTPM]":"22.0","Brain RNA - spinal cord [nTPM]":"14.0","Brain RNA - thalamus [nTPM]":"19.3","Brain RNA - white matter [nTPM]":"28.3","Single Cell Type RNA - Adipocytes [nTPM]":"8.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"9.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"18.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"20.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"6.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - dendritic cells [nTPM]":"5.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"12.3","Single Cell Type RNA - Early spermatids [nTPM]":"14.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"12.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.7","Single Cell Type RNA - Erythroid cells [nTPM]":"81.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.4","Single Cell Type RNA - Fibroblasts [nTPM]":"20.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"10.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"27.8","Single Cell Type RNA - Hepatocytes [nTPM]":"24.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.6","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.6","Single Cell Type RNA - Langerhans cells [nTPM]":"19.2","Single Cell Type RNA - Late spermatids [nTPM]":"20.4","Single Cell Type RNA - Leydig cells [nTPM]":"28.0","Single Cell Type RNA - Macrophages [nTPM]":"13.2","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"12.2","Single Cell Type RNA - Muller glia cells [nTPM]":"13.3","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.8","Single Cell Type RNA - Paneth cells [nTPM]":"15.6","Single Cell Type RNA - Peritubular cells [nTPM]":"20.3","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"24.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.1","Single Cell Type RNA - Spermatocytes [nTPM]":"6.3","Single Cell Type RNA - Spermatogonia [nTPM]":"10.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"33.8","Single Cell Type RNA - T-cells [nTPM]":"10.0","Single Cell Type RNA - Theca cells [nTPM]":"16.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.6","Single Cell Type RNA - Urothelial cells [nTPM]":"13.0"},{"Gene":"FLI1","Gene synonym":["EWSR2","SIC-1"],"Ensembl":"ENSG00000151702","Gene description":"Fli-1 proto-oncogene, ETS transcription factor","Uniprot":["Q01543"],"Chromosome":"11","Position":"128686535-128813267","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"35.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"B-cells":"65.7","Endothelial cells":"84.2","Hepatic stellate cells":"64.6","Kupffer cells":"86.4","Microglial cells":"231.4","monocytes":"68.4","NK-cells":"93.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"113.9","HUVEC TERT2":"60.5","REH":"49.8","TIME":"63.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA065030","HPA073099"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm","Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA065030":null,"HPA073099":"AB_2686572"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.46e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.60e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.79e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"3.7","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"2.3","Tissue RNA - bone marrow [nTPM]":"12.2","Tissue RNA - breast [nTPM]":"6.0","Tissue RNA - cerebellum [nTPM]":"2.1","Tissue RNA - cerebral cortex [nTPM]":"2.8","Tissue RNA - cervix [nTPM]":"5.7","Tissue RNA - choroid plexus [nTPM]":"1.2","Tissue RNA - colon [nTPM]":"3.7","Tissue RNA - duodenum [nTPM]":"3.2","Tissue RNA - endometrium 1 [nTPM]":"4.6","Tissue RNA - epididymis [nTPM]":"1.1","Tissue RNA - esophagus [nTPM]":"2.8","Tissue RNA - fallopian tube [nTPM]":"2.7","Tissue RNA - gallbladder [nTPM]":"6.1","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"1.8","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"2.1","Tissue RNA - liver [nTPM]":"2.8","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"4.7","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"3.5","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"2.9","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"2.2","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"4.0","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"35.8","Tissue RNA - stomach 1 [nTPM]":"4.3","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"3.9","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"6.6","Tissue RNA - tonsil [nTPM]":"10.4","Tissue RNA - urinary bladder [nTPM]":"6.7","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"5.6","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"1.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"9.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"18.5","Cell RNA - EFO-21 [nTPM]":"31.7","Cell RNA - fHDF\/TERT166 [nTPM]":"11.1","Cell RNA - GAMG [nTPM]":"1.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.8","Cell RNA - HBEC3-KT [nTPM]":"13.5","Cell RNA - HBF TERT88 [nTPM]":"4.1","Cell RNA - HDLM-2 [nTPM]":"9.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"113.9","Cell RNA - HeLa [nTPM]":"0.5","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"6.0","Cell RNA - HL-60 [nTPM]":"13.7","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.7","Cell RNA - hTERT-HME1 [nTPM]":"17.3","Cell RNA - hTERT-RPE1 [nTPM]":"11.1","Cell RNA - HUVEC TERT2 [nTPM]":"60.5","Cell RNA - JURKAT [nTPM]":"25.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"23.3","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"13.3","Cell RNA - NB-4 [nTPM]":"8.1","Cell RNA - NTERA-2 [nTPM]":"1.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"49.8","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"19.4","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"20.4","Cell RNA - TIME [nTPM]":"63.0","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"7.3","Cell RNA - U-266\/84 [nTPM]":"16.4","Cell RNA - U-698 [nTPM]":"16.6","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"31.8","Cell RNA - WM-115 [nTPM]":"5.2","Blood RNA - basophil [nTPM]":"34.5","Blood RNA - classical monocyte [nTPM]":"15.5","Blood RNA - eosinophil [nTPM]":"24.5","Blood RNA - gdT-cell [nTPM]":"10.1","Blood RNA - intermediate monocyte [nTPM]":"15.3","Blood RNA - MAIT T-cell [nTPM]":"11.9","Blood RNA - memory B-cell [nTPM]":"6.8","Blood RNA - memory CD4 T-cell [nTPM]":"8.9","Blood RNA - memory CD8 T-cell [nTPM]":"8.2","Blood RNA - myeloid DC [nTPM]":"19.1","Blood RNA - naive B-cell [nTPM]":"6.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.7","Blood RNA - naive CD8 T-cell [nTPM]":"8.2","Blood RNA - neutrophil [nTPM]":"11.8","Blood RNA - NK-cell [nTPM]":"12.3","Blood RNA - non-classical monocyte [nTPM]":"19.1","Blood RNA - plasmacytoid DC [nTPM]":"3.3","Blood RNA - T-reg [nTPM]":"11.1","Blood RNA - total PBMC [nTPM]":"20.1","Brain RNA - amygdala [nTPM]":"3.7","Brain RNA - basal ganglia [nTPM]":"2.3","Brain RNA - cerebellum [nTPM]":"2.1","Brain RNA - cerebral cortex [nTPM]":"2.8","Brain RNA - hippocampal formation [nTPM]":"1.8","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"4.7","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"3.9","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"53.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"65.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"0.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"43.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.6","Single Cell Type RNA - Endothelial cells [nTPM]":"84.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"23.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"5.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"22.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"64.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"86.4","Single Cell Type RNA - Langerhans cells [nTPM]":"24.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"60.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"231.4","Single Cell Type RNA - monocytes [nTPM]":"68.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"93.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"56.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"52.8","Single Cell Type RNA - Theca cells [nTPM]":"0.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"FLT3","Gene synonym":["CD135","FLK2","STK1"],"Ensembl":"ENSG00000122025","Gene description":"Fms related receptor tyrosine kinase 3","Uniprot":["P36888"],"Chromosome":"13","Position":"28003274-28100592","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"5.3","brain":"4.9","lymphoid tissue":"6.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"24.4","Inhibitory neurons":"59.9","Kupffer cells":"29.1","Langerhans cells":"21.4","Macrophages":"16.9","monocytes":"39.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"1.8"},"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"4.9"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"13","RNA blood cell specific nTPM":{"myeloid DC":"68.7","plasmacytoid DC":"26.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"19","RNA blood lineage specific nTPM":{"dendritic cells":"68.7"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"11","RNA cell line specific nTPM":{"REH":"42.5","THP-1":"26.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA047539"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"210000","Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":null,"Antibody RRID":{"HPA047539":"AB_2680080"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.96e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-7"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.99e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.37e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.22e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.5","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.3","Tissue RNA - appendix [nTPM]":"3.0","Tissue RNA - basal ganglia [nTPM]":"0.2","Tissue RNA - bone marrow [nTPM]":"5.3","Tissue RNA - breast [nTPM]":"1.5","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"0.8","Tissue RNA - cervix [nTPM]":"0.5","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.6","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.2","Tissue RNA - hypothalamus [nTPM]":"0.5","Tissue RNA - kidney [nTPM]":"1.5","Tissue RNA - liver [nTPM]":"0.5","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"1.3","Tissue RNA - midbrain [nTPM]":"0.9","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.7","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"5.7","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"0.8","Tissue RNA - thymus [nTPM]":"4.7","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"3.6","Tissue RNA - urinary bladder [nTPM]":"1.3","Tissue RNA - vagina [nTPM]":"0.1","Tissue RNA - white matter [nTPM]":"0.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.9","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"0.6","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"42.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"26.6","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"3.6","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"68.7","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"26.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"2.7","Brain RNA - amygdala [nTPM]":"0.3","Brain RNA - basal ganglia [nTPM]":"0.2","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"0.8","Brain RNA - hippocampal formation [nTPM]":"0.2","Brain RNA - hypothalamus [nTPM]":"0.5","Brain RNA - medulla oblongata [nTPM]":"1.3","Brain RNA - midbrain [nTPM]":"0.9","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"0.8","Brain RNA - white matter [nTPM]":"0.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"2.3","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.7","Single Cell Type RNA - Early spermatids [nTPM]":"3.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"29.1","Single Cell Type RNA - Langerhans cells [nTPM]":"21.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"16.9","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"39.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.7","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"FOXO1","Gene synonym":["FKH1","FKHR","FOXO1A"],"Ensembl":"ENSG00000150907","Gene description":"Forkhead box O1","Uniprot":["Q12778"],"Chromosome":"13","Position":"40555667-40666641","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Apoptosis","Autophagy","Differentiation","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"91.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"177.3","Endometrial stromal cells":"161.0","Granulosa cells":"177.9","Oligodendrocytes":"131.5","Skeletal myocytes":"131.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"40.4","Daudi":"45.3","HSkMC":"53.6","U-698":"57.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001252","CAB022326"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Approved","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB022326":null,"HPA001252":"AB_1078906"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.35e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.74e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.35e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.65e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"43.2","Tissue RNA - adrenal gland [nTPM]":"9.7","Tissue RNA - amygdala [nTPM]":"11.2","Tissue RNA - appendix [nTPM]":"13.1","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"13.8","Tissue RNA - breast [nTPM]":"27.6","Tissue RNA - cerebellum [nTPM]":"10.0","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"19.1","Tissue RNA - choroid plexus [nTPM]":"16.7","Tissue RNA - colon [nTPM]":"13.8","Tissue RNA - duodenum [nTPM]":"5.0","Tissue RNA - endometrium 1 [nTPM]":"39.1","Tissue RNA - epididymis [nTPM]":"6.5","Tissue RNA - esophagus [nTPM]":"13.0","Tissue RNA - fallopian tube [nTPM]":"25.7","Tissue RNA - gallbladder [nTPM]":"14.5","Tissue RNA - heart muscle [nTPM]":"13.9","Tissue RNA - hippocampal formation [nTPM]":"9.1","Tissue RNA - hypothalamus [nTPM]":"11.8","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"38.5","Tissue RNA - lung [nTPM]":"16.8","Tissue RNA - lymph node [nTPM]":"23.8","Tissue RNA - medulla oblongata [nTPM]":"14.1","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"65.6","Tissue RNA - pancreas [nTPM]":"16.5","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"11.2","Tissue RNA - pons [nTPM]":"12.7","Tissue RNA - prostate [nTPM]":"10.1","Tissue RNA - rectum [nTPM]":"9.6","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"9.8","Tissue RNA - seminal vesicle [nTPM]":"10.1","Tissue RNA - skeletal muscle [nTPM]":"91.0","Tissue RNA - skin 1 [nTPM]":"18.0","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"27.0","Tissue RNA - spinal cord [nTPM]":"10.5","Tissue RNA - spleen [nTPM]":"15.7","Tissue RNA - stomach 1 [nTPM]":"9.5","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"11.6","Tissue RNA - thyroid gland [nTPM]":"19.0","Tissue RNA - tongue [nTPM]":"22.2","Tissue RNA - tonsil [nTPM]":"24.0","Tissue RNA - urinary bladder [nTPM]":"13.4","Tissue RNA - vagina [nTPM]":"17.4","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"0.7","Cell RNA - A549 [nTPM]":"1.7","Cell RNA - AF22 [nTPM]":"12.4","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"40.4","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"11.8","Cell RNA - BJ [nTPM]":"1.8","Cell RNA - BJ hTERT+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.3","Cell RNA - CACO-2 [nTPM]":"3.7","Cell RNA - CAPAN-2 [nTPM]":"3.0","Cell RNA - Daudi [nTPM]":"45.3","Cell RNA - EFO-21 [nTPM]":"8.1","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"1.9","Cell RNA - HaCaT [nTPM]":"10.7","Cell RNA - HAP1 [nTPM]":"9.8","Cell RNA - HBEC3-KT [nTPM]":"5.3","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"20.9","Cell RNA - HEK 293 [nTPM]":"10.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.4","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"19.1","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"53.6","Cell RNA - hTCEpi [nTPM]":"35.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"6.7","Cell RNA - hTERT-RPE1 [nTPM]":"2.5","Cell RNA - HUVEC TERT2 [nTPM]":"31.7","Cell RNA - JURKAT [nTPM]":"3.3","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"14.0","Cell RNA - LHCN-M2 [nTPM]":"3.1","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"18.0","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"3.1","Cell RNA - REH [nTPM]":"32.4","Cell RNA - RH-30 [nTPM]":"14.3","Cell RNA - RPMI-8226 [nTPM]":"3.6","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"5.8","Cell RNA - SCLC-21H [nTPM]":"2.6","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"8.5","Cell RNA - SK-MEL-30 [nTPM]":"1.8","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"18.6","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"2.3","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"1.1","Cell RNA - U-266\/70 [nTPM]":"7.9","Cell RNA - U-266\/84 [nTPM]":"3.3","Cell RNA - U-698 [nTPM]":"57.8","Cell RNA - U-87 MG [nTPM]":"1.2","Cell RNA - U-937 [nTPM]":"2.1","Cell RNA - WM-115 [nTPM]":"5.7","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"1.3","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"3.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"5.8","Blood RNA - naive CD4 T-cell [nTPM]":"5.5","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"5.1","Blood RNA - total PBMC [nTPM]":"1.0","Brain RNA - amygdala [nTPM]":"11.2","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"10.0","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"9.1","Brain RNA - hypothalamus [nTPM]":"11.8","Brain RNA - medulla oblongata [nTPM]":"14.1","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"12.7","Brain RNA - spinal cord [nTPM]":"10.5","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"57.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.4","Single Cell Type RNA - Astrocytes [nTPM]":"177.3","Single Cell Type RNA - B-cells [nTPM]":"29.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"29.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"9.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"22.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"55.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"161.0","Single Cell Type RNA - Endothelial cells [nTPM]":"50.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.8","Single Cell Type RNA - Fibroblasts [nTPM]":"40.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"118.8","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"177.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"84.3","Single Cell Type RNA - Hepatocytes [nTPM]":"47.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"14.6","Single Cell Type RNA - Langerhans cells [nTPM]":"26.9","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"18.6","Single Cell Type RNA - Macrophages [nTPM]":"18.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"117.1","Single Cell Type RNA - monocytes [nTPM]":"18.4","Single Cell Type RNA - Muller glia cells [nTPM]":"5.5","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"47.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"131.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.5","Single Cell Type RNA - Paneth cells [nTPM]":"16.3","Single Cell Type RNA - Peritubular cells [nTPM]":"13.2","Single Cell Type RNA - Plasma cells [nTPM]":"32.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"7.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"131.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.3","Single Cell Type RNA - Spermatocytes [nTPM]":"6.4","Single Cell Type RNA - Spermatogonia [nTPM]":"14.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"40.3","Single Cell Type RNA - Theca cells [nTPM]":"64.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.5","Single Cell Type RNA - Urothelial cells [nTPM]":"13.0"},{"Gene":"FZD7","Gene synonym":["FzE3"],"Ensembl":"ENSG00000155760","Gene description":"Frizzled class receptor 7","Uniprot":["O75084"],"Chromosome":"2","Position":"202033855-202038441","Protein class":["G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":["Wnt signaling pathway"],"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"30.9","Breast myoepithelial cells":"37.0","Cardiomyocytes":"21.1","Fibroblasts":"23.5","Proximal enterocytes":"21.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"30.2"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ":"42.8","BJ hTERT+":"48.4","CAPAN-2":"62.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA059979","HPA069165","HPA076183"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA059979":null,"HPA069165":"AB_2686096","HPA076183":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.89e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.30e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.71e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-3"},"Tissue RNA - adipose tissue [nTPM]":"10.2","Tissue RNA - adrenal gland [nTPM]":"3.0","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"5.6","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"15.5","Tissue RNA - cerebellum [nTPM]":"30.2","Tissue RNA - cerebral cortex [nTPM]":"4.3","Tissue RNA - cervix [nTPM]":"13.2","Tissue RNA - choroid plexus [nTPM]":"6.3","Tissue RNA - colon [nTPM]":"36.7","Tissue RNA - duodenum [nTPM]":"6.9","Tissue RNA - endometrium 1 [nTPM]":"18.4","Tissue RNA - epididymis [nTPM]":"14.1","Tissue RNA - esophagus [nTPM]":"9.4","Tissue RNA - fallopian tube [nTPM]":"16.8","Tissue RNA - gallbladder [nTPM]":"6.3","Tissue RNA - heart muscle [nTPM]":"14.4","Tissue RNA - hippocampal formation [nTPM]":"8.8","Tissue RNA - hypothalamus [nTPM]":"5.0","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"3.9","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"25.0","Tissue RNA - pancreas [nTPM]":"1.7","Tissue RNA - parathyroid gland [nTPM]":"1.1","Tissue RNA - pituitary gland [nTPM]":"9.3","Tissue RNA - placenta [nTPM]":"5.7","Tissue RNA - pons [nTPM]":"5.5","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"21.7","Tissue RNA - seminal vesicle [nTPM]":"23.5","Tissue RNA - skeletal muscle [nTPM]":"26.7","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"10.8","Tissue RNA - smooth muscle [nTPM]":"11.1","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"1.9","Tissue RNA - stomach 1 [nTPM]":"5.9","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"4.5","Tissue RNA - thymus [nTPM]":"1.1","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"9.5","Tissue RNA - tonsil [nTPM]":"3.8","Tissue RNA - urinary bladder [nTPM]":"27.1","Tissue RNA - vagina [nTPM]":"15.3","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"10.3","Cell RNA - A549 [nTPM]":"5.2","Cell RNA - AF22 [nTPM]":"33.2","Cell RNA - AN3-CA [nTPM]":"10.8","Cell RNA - ASC diff [nTPM]":"10.6","Cell RNA - ASC TERT1 [nTPM]":"7.9","Cell RNA - BEWO [nTPM]":"14.8","Cell RNA - BJ [nTPM]":"42.8","Cell RNA - BJ hTERT+ [nTPM]":"48.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"13.9","Cell RNA - CACO-2 [nTPM]":"32.2","Cell RNA - CAPAN-2 [nTPM]":"62.7","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"25.1","Cell RNA - fHDF\/TERT166 [nTPM]":"26.2","Cell RNA - GAMG [nTPM]":"7.9","Cell RNA - HaCaT [nTPM]":"10.6","Cell RNA - HAP1 [nTPM]":"6.0","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"13.7","Cell RNA - HDLM-2 [nTPM]":"5.4","Cell RNA - HEK 293 [nTPM]":"8.6","Cell RNA - HEL [nTPM]":"1.1","Cell RNA - HeLa [nTPM]":"2.1","Cell RNA - Hep G2 [nTPM]":"2.7","Cell RNA - HHSteC [nTPM]":"7.2","Cell RNA - HL-60 [nTPM]":"2.1","Cell RNA - HMC-1 [nTPM]":"2.1","Cell RNA - HSkMC [nTPM]":"7.6","Cell RNA - hTCEpi [nTPM]":"1.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"3.7","Cell RNA - hTERT-RPE1 [nTPM]":"9.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"2.9","Cell RNA - Karpas-707 [nTPM]":"2.6","Cell RNA - LHCN-M2 [nTPM]":"9.8","Cell RNA - MCF7 [nTPM]":"4.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"5.7","Cell RNA - NTERA-2 [nTPM]":"36.6","Cell RNA - OE19 [nTPM]":"2.0","Cell RNA - PC-3 [nTPM]":"3.5","Cell RNA - REH [nTPM]":"4.2","Cell RNA - RH-30 [nTPM]":"6.4","Cell RNA - RPMI-8226 [nTPM]":"1.1","Cell RNA - RPTEC TERT1 [nTPM]":"1.9","Cell RNA - RT4 [nTPM]":"6.1","Cell RNA - SCLC-21H [nTPM]":"5.5","Cell RNA - SH-SY5Y [nTPM]":"12.6","Cell RNA - SiHa [nTPM]":"5.4","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"6.8","Cell RNA - SuSa [nTPM]":"26.7","Cell RNA - T-47d [nTPM]":"3.8","Cell RNA - THP-1 [nTPM]":"2.5","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"23.8","Cell RNA - U-2 OS [nTPM]":"8.8","Cell RNA - U-2197 [nTPM]":"15.0","Cell RNA - U-251 MG [nTPM]":"5.4","Cell RNA - U-266\/70 [nTPM]":"2.7","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"4.9","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"16.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"30.2","Brain RNA - cerebral cortex [nTPM]":"4.3","Brain RNA - hippocampal formation [nTPM]":"8.8","Brain RNA - hypothalamus [nTPM]":"5.0","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"5.5","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"4.5","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"3.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.6","Single Cell Type RNA - B-cells [nTPM]":"2.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"30.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"37.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"23.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.6","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"7.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.8","Single Cell Type RNA - Langerhans cells [nTPM]":"5.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.5","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"2.0","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"7.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.6","Single Cell Type RNA - Paneth cells [nTPM]":"2.1","Single Cell Type RNA - Peritubular cells [nTPM]":"4.9","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.6","Single Cell Type RNA - Urothelial cells [nTPM]":"1.8"},{"Gene":"GALNT12","Gene synonym":["GalNAc-T12"],"Ensembl":"ENSG00000119514","Gene description":"Polypeptide N-acetylgalactosaminyltransferase 12","Uniprot":["Q8IXK2"],"Chromosome":"9","Position":"98807670-98850081","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"epididymis":"74.7","intestine":"55.8","stomach 1":"54.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"101.2","Intestinal goblet cells":"142.4","Undifferentiated cells":"42.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"OE19":"128.4","U-2197":"160.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048292","HPA071076"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"47000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 27: Mucus-secreting cells - Mucin production","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cell Junctions"],"Antibody RRID":{"HPA048292":"AB_2680343","HPA071076":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.05e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.87e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.0","Tissue RNA - adrenal gland [nTPM]":"2.0","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"7.7","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"3.4","Tissue RNA - cerebellum [nTPM]":"6.5","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"4.3","Tissue RNA - colon [nTPM]":"55.3","Tissue RNA - duodenum [nTPM]":"34.2","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"74.7","Tissue RNA - esophagus [nTPM]":"19.6","Tissue RNA - fallopian tube [nTPM]":"7.5","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"1.1","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"4.8","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"11.7","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"1.4","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"13.6","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"4.6","Tissue RNA - rectum [nTPM]":"55.8","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"25.5","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"27.1","Tissue RNA - smooth muscle [nTPM]":"14.0","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"2.2","Tissue RNA - stomach 1 [nTPM]":"54.8","Tissue RNA - testis [nTPM]":"4.6","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"3.3","Tissue RNA - thyroid gland [nTPM]":"14.7","Tissue RNA - tongue [nTPM]":"0.6","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"11.9","Tissue RNA - vagina [nTPM]":"4.6","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"5.4","Cell RNA - A549 [nTPM]":"4.1","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"13.5","Cell RNA - ASC diff [nTPM]":"10.0","Cell RNA - ASC TERT1 [nTPM]":"7.8","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"2.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"21.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"12.2","Cell RNA - HaCaT [nTPM]":"38.0","Cell RNA - HAP1 [nTPM]":"2.9","Cell RNA - HBEC3-KT [nTPM]":"1.3","Cell RNA - HBF TERT88 [nTPM]":"1.6","Cell RNA - HDLM-2 [nTPM]":"26.2","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"0.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.3","Cell RNA - JURKAT [nTPM]":"19.3","Cell RNA - K-562 [nTPM]":"30.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"13.9","Cell RNA - MOLT-4 [nTPM]":"2.6","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"16.7","Cell RNA - OE19 [nTPM]":"128.4","Cell RNA - PC-3 [nTPM]":"5.6","Cell RNA - REH [nTPM]":"6.5","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"7.7","Cell RNA - SCLC-21H [nTPM]":"12.4","Cell RNA - SH-SY5Y [nTPM]":"1.1","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"30.6","Cell RNA - SK-MEL-30 [nTPM]":"3.0","Cell RNA - SuSa [nTPM]":"7.7","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"4.5","Cell RNA - TIME [nTPM]":"4.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.3","Cell RNA - U-2197 [nTPM]":"160.9","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.1","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"2.3","Cell RNA - U-87 MG [nTPM]":"37.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.5","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"6.5","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.1","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"1.4","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"25.7","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"2.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"16.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"101.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"11.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"1.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"142.4","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"3.9","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"3.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"3.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"32.0","Single Cell Type RNA - Paneth cells [nTPM]":"36.5","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.5","Single Cell Type RNA - Spermatocytes [nTPM]":"5.9","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"4.5","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"42.5","Single Cell Type RNA - Urothelial cells [nTPM]":"11.1"},{"Gene":"GNA12","Gene synonym":["gep"],"Ensembl":"ENSG00000146535","Gene description":"G protein subunit alpha 12","Uniprot":["Q03113"],"Chromosome":"7","Position":"2728105-2844308","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"53.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"68.3","Syncytiotrophoblasts":"173.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010046"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 70: Brain - Nervous system development","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB010046":"AB_2263416"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.71e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.27e-4"},"Tissue RNA - adipose tissue [nTPM]":"17.8","Tissue RNA - adrenal gland [nTPM]":"14.9","Tissue RNA - amygdala [nTPM]":"42.5","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"47.1","Tissue RNA - bone marrow [nTPM]":"11.0","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"38.4","Tissue RNA - cerebral cortex [nTPM]":"35.8","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"18.3","Tissue RNA - colon [nTPM]":"16.6","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"17.0","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"12.9","Tissue RNA - gallbladder [nTPM]":"9.4","Tissue RNA - heart muscle [nTPM]":"17.9","Tissue RNA - hippocampal formation [nTPM]":"36.1","Tissue RNA - hypothalamus [nTPM]":"39.6","Tissue RNA - kidney [nTPM]":"8.6","Tissue RNA - liver [nTPM]":"9.3","Tissue RNA - lung [nTPM]":"12.8","Tissue RNA - lymph node [nTPM]":"12.8","Tissue RNA - medulla oblongata [nTPM]":"53.2","Tissue RNA - midbrain [nTPM]":"43.9","Tissue RNA - ovary [nTPM]":"18.2","Tissue RNA - pancreas [nTPM]":"11.9","Tissue RNA - parathyroid gland [nTPM]":"8.0","Tissue RNA - pituitary gland [nTPM]":"12.3","Tissue RNA - placenta [nTPM]":"24.4","Tissue RNA - pons [nTPM]":"42.5","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"6.1","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"8.0","Tissue RNA - seminal vesicle [nTPM]":"11.4","Tissue RNA - skeletal muscle [nTPM]":"6.7","Tissue RNA - skin 1 [nTPM]":"5.0","Tissue RNA - small intestine [nTPM]":"11.3","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"46.2","Tissue RNA - spleen [nTPM]":"10.6","Tissue RNA - stomach 1 [nTPM]":"11.6","Tissue RNA - testis [nTPM]":"10.1","Tissue RNA - thalamus [nTPM]":"52.6","Tissue RNA - thymus [nTPM]":"5.6","Tissue RNA - thyroid gland [nTPM]":"6.7","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"10.1","Tissue RNA - urinary bladder [nTPM]":"16.6","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"42.3","Cell RNA - A-431 [nTPM]":"35.5","Cell RNA - A549 [nTPM]":"19.1","Cell RNA - AF22 [nTPM]":"19.4","Cell RNA - AN3-CA [nTPM]":"29.2","Cell RNA - ASC diff [nTPM]":"30.4","Cell RNA - ASC TERT1 [nTPM]":"24.1","Cell RNA - BEWO [nTPM]":"53.5","Cell RNA - BJ [nTPM]":"29.1","Cell RNA - BJ hTERT+ [nTPM]":"33.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"30.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.3","Cell RNA - CACO-2 [nTPM]":"18.4","Cell RNA - CAPAN-2 [nTPM]":"24.5","Cell RNA - Daudi [nTPM]":"7.5","Cell RNA - EFO-21 [nTPM]":"19.4","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"64.7","Cell RNA - HaCaT [nTPM]":"15.6","Cell RNA - HAP1 [nTPM]":"13.5","Cell RNA - HBEC3-KT [nTPM]":"30.1","Cell RNA - HBF TERT88 [nTPM]":"20.9","Cell RNA - HDLM-2 [nTPM]":"89.9","Cell RNA - HEK 293 [nTPM]":"13.5","Cell RNA - HEL [nTPM]":"15.3","Cell RNA - HeLa [nTPM]":"9.9","Cell RNA - Hep G2 [nTPM]":"19.6","Cell RNA - HHSteC [nTPM]":"35.4","Cell RNA - HL-60 [nTPM]":"2.5","Cell RNA - HMC-1 [nTPM]":"13.1","Cell RNA - HSkMC [nTPM]":"23.5","Cell RNA - hTCEpi [nTPM]":"16.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.3","Cell RNA - hTERT-HME1 [nTPM]":"24.4","Cell RNA - hTERT-RPE1 [nTPM]":"31.8","Cell RNA - HUVEC TERT2 [nTPM]":"33.3","Cell RNA - JURKAT [nTPM]":"10.6","Cell RNA - K-562 [nTPM]":"17.3","Cell RNA - Karpas-707 [nTPM]":"23.0","Cell RNA - LHCN-M2 [nTPM]":"28.1","Cell RNA - MCF7 [nTPM]":"16.8","Cell RNA - MOLT-4 [nTPM]":"4.1","Cell RNA - NB-4 [nTPM]":"14.1","Cell RNA - NTERA-2 [nTPM]":"27.3","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"32.9","Cell RNA - REH [nTPM]":"26.8","Cell RNA - RH-30 [nTPM]":"22.4","Cell RNA - RPMI-8226 [nTPM]":"15.2","Cell RNA - RPTEC TERT1 [nTPM]":"11.4","Cell RNA - RT4 [nTPM]":"23.8","Cell RNA - SCLC-21H [nTPM]":"15.4","Cell RNA - SH-SY5Y [nTPM]":"22.3","Cell RNA - SiHa [nTPM]":"16.4","Cell RNA - SK-BR-3 [nTPM]":"24.4","Cell RNA - SK-MEL-30 [nTPM]":"12.2","Cell RNA - SuSa [nTPM]":"27.6","Cell RNA - T-47d [nTPM]":"13.6","Cell RNA - THP-1 [nTPM]":"20.9","Cell RNA - TIME [nTPM]":"39.5","Cell RNA - U-138 MG [nTPM]":"33.6","Cell RNA - U-2 OS [nTPM]":"39.9","Cell RNA - U-2197 [nTPM]":"33.2","Cell RNA - U-251 MG [nTPM]":"48.6","Cell RNA - U-266\/70 [nTPM]":"16.1","Cell RNA - U-266\/84 [nTPM]":"20.3","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"36.1","Cell RNA - U-937 [nTPM]":"22.5","Cell RNA - WM-115 [nTPM]":"33.7","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"1.3","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"1.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.5","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"1.8","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"42.5","Brain RNA - basal ganglia [nTPM]":"47.1","Brain RNA - cerebellum [nTPM]":"38.4","Brain RNA - cerebral cortex [nTPM]":"35.8","Brain RNA - hippocampal formation [nTPM]":"36.1","Brain RNA - hypothalamus [nTPM]":"39.6","Brain RNA - medulla oblongata [nTPM]":"53.2","Brain RNA - midbrain [nTPM]":"43.9","Brain RNA - pons [nTPM]":"42.5","Brain RNA - spinal cord [nTPM]":"46.2","Brain RNA - thalamus [nTPM]":"52.6","Brain RNA - white matter [nTPM]":"42.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.7","Single Cell Type RNA - Astrocytes [nTPM]":"41.8","Single Cell Type RNA - B-cells [nTPM]":"22.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"6.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"10.0","Single Cell Type RNA - Club cells [nTPM]":"6.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"63.7","Single Cell Type RNA - dendritic cells [nTPM]":"16.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.9","Single Cell Type RNA - Early spermatids [nTPM]":"13.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.8","Single Cell Type RNA - Endothelial cells [nTPM]":"16.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"31.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"17.0","Single Cell Type RNA - Fibroblasts [nTPM]":"19.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"19.2","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"25.4","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.5","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"21.6","Single Cell Type RNA - Langerhans cells [nTPM]":"63.5","Single Cell Type RNA - Late spermatids [nTPM]":"13.6","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"25.8","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"22.5","Single Cell Type RNA - monocytes [nTPM]":"21.7","Single Cell Type RNA - Muller glia cells [nTPM]":"16.1","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"68.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"29.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"4.0","Single Cell Type RNA - Peritubular cells [nTPM]":"18.8","Single Cell Type RNA - Plasma cells [nTPM]":"7.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"9.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"173.2","Single Cell Type RNA - T-cells [nTPM]":"6.2","Single Cell Type RNA - Theca cells [nTPM]":"23.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.3","Single Cell Type RNA - Urothelial cells [nTPM]":"3.2"},{"Gene":"GNA13","Gene synonym":["G13","MGC46138"],"Ensembl":"ENSG00000120063","Gene description":"G protein subunit alpha 13","Uniprot":["Q14344"],"Chromosome":"17","Position":"65009289-65056740","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transducer"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"144.5"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"537.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA010087"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA010087":"AB_10601478"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.21e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.77e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Tissue RNA - adipose tissue [nTPM]":"23.7","Tissue RNA - adrenal gland [nTPM]":"22.5","Tissue RNA - amygdala [nTPM]":"21.3","Tissue RNA - appendix [nTPM]":"41.5","Tissue RNA - basal ganglia [nTPM]":"23.9","Tissue RNA - bone marrow [nTPM]":"144.5","Tissue RNA - breast [nTPM]":"15.8","Tissue RNA - cerebellum [nTPM]":"25.0","Tissue RNA - cerebral cortex [nTPM]":"22.5","Tissue RNA - cervix [nTPM]":"17.6","Tissue RNA - choroid plexus [nTPM]":"21.3","Tissue RNA - colon [nTPM]":"27.7","Tissue RNA - duodenum [nTPM]":"21.0","Tissue RNA - endometrium 1 [nTPM]":"17.9","Tissue RNA - epididymis [nTPM]":"10.5","Tissue RNA - esophagus [nTPM]":"18.2","Tissue RNA - fallopian tube [nTPM]":"15.9","Tissue RNA - gallbladder [nTPM]":"26.5","Tissue RNA - heart muscle [nTPM]":"12.6","Tissue RNA - hippocampal formation [nTPM]":"20.2","Tissue RNA - hypothalamus [nTPM]":"26.6","Tissue RNA - kidney [nTPM]":"17.6","Tissue RNA - liver [nTPM]":"27.0","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"46.8","Tissue RNA - medulla oblongata [nTPM]":"26.9","Tissue RNA - midbrain [nTPM]":"21.7","Tissue RNA - ovary [nTPM]":"22.6","Tissue RNA - pancreas [nTPM]":"15.3","Tissue RNA - parathyroid gland [nTPM]":"15.8","Tissue RNA - pituitary gland [nTPM]":"8.3","Tissue RNA - placenta [nTPM]":"39.3","Tissue RNA - pons [nTPM]":"30.1","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"26.2","Tissue RNA - retina [nTPM]":"17.2","Tissue RNA - salivary gland [nTPM]":"10.4","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"36.8","Tissue RNA - skin 1 [nTPM]":"12.1","Tissue RNA - small intestine [nTPM]":"23.3","Tissue RNA - smooth muscle [nTPM]":"22.9","Tissue RNA - spinal cord [nTPM]":"25.4","Tissue RNA - spleen [nTPM]":"33.5","Tissue RNA - stomach 1 [nTPM]":"18.0","Tissue RNA - testis [nTPM]":"15.4","Tissue RNA - thalamus [nTPM]":"23.7","Tissue RNA - thymus [nTPM]":"49.9","Tissue RNA - thyroid gland [nTPM]":"17.9","Tissue RNA - tongue [nTPM]":"38.6","Tissue RNA - tonsil [nTPM]":"44.6","Tissue RNA - urinary bladder [nTPM]":"30.5","Tissue RNA - vagina [nTPM]":"12.3","Tissue RNA - white matter [nTPM]":"35.2","Cell RNA - A-431 [nTPM]":"33.3","Cell RNA - A549 [nTPM]":"36.9","Cell RNA - AF22 [nTPM]":"32.6","Cell RNA - AN3-CA [nTPM]":"21.6","Cell RNA - ASC diff [nTPM]":"31.8","Cell RNA - ASC TERT1 [nTPM]":"29.5","Cell RNA - BEWO [nTPM]":"32.2","Cell RNA - BJ [nTPM]":"25.3","Cell RNA - BJ hTERT+ [nTPM]":"28.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"39.7","Cell RNA - CACO-2 [nTPM]":"20.7","Cell RNA - CAPAN-2 [nTPM]":"23.0","Cell RNA - Daudi [nTPM]":"130.0","Cell RNA - EFO-21 [nTPM]":"16.1","Cell RNA - fHDF\/TERT166 [nTPM]":"26.6","Cell RNA - GAMG [nTPM]":"42.0","Cell RNA - HaCaT [nTPM]":"22.5","Cell RNA - HAP1 [nTPM]":"35.0","Cell RNA - HBEC3-KT [nTPM]":"29.4","Cell RNA - HBF TERT88 [nTPM]":"51.5","Cell RNA - HDLM-2 [nTPM]":"35.4","Cell RNA - HEK 293 [nTPM]":"19.5","Cell RNA - HEL [nTPM]":"69.0","Cell RNA - HeLa [nTPM]":"20.7","Cell RNA - Hep G2 [nTPM]":"38.7","Cell RNA - HHSteC [nTPM]":"45.7","Cell RNA - HL-60 [nTPM]":"54.2","Cell RNA - HMC-1 [nTPM]":"45.5","Cell RNA - HSkMC [nTPM]":"23.9","Cell RNA - hTCEpi [nTPM]":"43.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"32.2","Cell RNA - hTERT-HME1 [nTPM]":"42.0","Cell RNA - hTERT-RPE1 [nTPM]":"29.1","Cell RNA - HUVEC TERT2 [nTPM]":"48.6","Cell RNA - JURKAT [nTPM]":"33.6","Cell RNA - K-562 [nTPM]":"29.7","Cell RNA - Karpas-707 [nTPM]":"82.3","Cell RNA - LHCN-M2 [nTPM]":"36.9","Cell RNA - MCF7 [nTPM]":"29.3","Cell RNA - MOLT-4 [nTPM]":"88.9","Cell RNA - NB-4 [nTPM]":"18.8","Cell RNA - NTERA-2 [nTPM]":"19.4","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"25.7","Cell RNA - REH [nTPM]":"49.0","Cell RNA - RH-30 [nTPM]":"64.8","Cell RNA - RPMI-8226 [nTPM]":"47.2","Cell RNA - RPTEC TERT1 [nTPM]":"32.0","Cell RNA - RT4 [nTPM]":"53.3","Cell RNA - SCLC-21H [nTPM]":"24.5","Cell RNA - SH-SY5Y [nTPM]":"48.8","Cell RNA - SiHa [nTPM]":"19.7","Cell RNA - SK-BR-3 [nTPM]":"34.8","Cell RNA - SK-MEL-30 [nTPM]":"43.8","Cell RNA - SuSa [nTPM]":"62.1","Cell RNA - T-47d [nTPM]":"40.7","Cell RNA - THP-1 [nTPM]":"50.0","Cell RNA - TIME [nTPM]":"37.9","Cell RNA - U-138 MG [nTPM]":"58.4","Cell RNA - U-2 OS [nTPM]":"48.8","Cell RNA - U-2197 [nTPM]":"25.0","Cell RNA - U-251 MG [nTPM]":"33.2","Cell RNA - U-266\/70 [nTPM]":"57.3","Cell RNA - U-266\/84 [nTPM]":"79.4","Cell RNA - U-698 [nTPM]":"151.4","Cell RNA - U-87 MG [nTPM]":"20.1","Cell RNA - U-937 [nTPM]":"32.2","Cell RNA - WM-115 [nTPM]":"30.4","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"6.0","Blood RNA - eosinophil [nTPM]":"7.6","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"12.5","Blood RNA - MAIT T-cell [nTPM]":"5.7","Blood RNA - memory B-cell [nTPM]":"4.5","Blood RNA - memory CD4 T-cell [nTPM]":"6.8","Blood RNA - memory CD8 T-cell [nTPM]":"6.8","Blood RNA - myeloid DC [nTPM]":"5.2","Blood RNA - naive B-cell [nTPM]":"4.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.4","Blood RNA - neutrophil [nTPM]":"13.8","Blood RNA - NK-cell [nTPM]":"6.8","Blood RNA - non-classical monocyte [nTPM]":"8.5","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"9.7","Blood RNA - total PBMC [nTPM]":"4.0","Brain RNA - amygdala [nTPM]":"21.3","Brain RNA - basal ganglia [nTPM]":"23.9","Brain RNA - cerebellum [nTPM]":"25.0","Brain RNA - cerebral cortex [nTPM]":"22.5","Brain RNA - hippocampal formation [nTPM]":"20.2","Brain RNA - hypothalamus [nTPM]":"26.6","Brain RNA - medulla oblongata [nTPM]":"26.9","Brain RNA - midbrain [nTPM]":"21.7","Brain RNA - pons [nTPM]":"30.1","Brain RNA - spinal cord [nTPM]":"25.4","Brain RNA - thalamus [nTPM]":"23.7","Brain RNA - white matter [nTPM]":"35.2","Single Cell Type RNA - Adipocytes [nTPM]":"34.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.0","Single Cell Type RNA - Astrocytes [nTPM]":"68.9","Single Cell Type RNA - B-cells [nTPM]":"80.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"67.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"27.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"13.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"42.1","Single Cell Type RNA - Bipolar cells [nTPM]":"5.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - dendritic cells [nTPM]":"60.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"82.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"4.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.6","Single Cell Type RNA - Endothelial cells [nTPM]":"35.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"21.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"20.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.1","Single Cell Type RNA - Fibroblasts [nTPM]":"24.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"49.9","Single Cell Type RNA - granulocytes [nTPM]":"30.4","Single Cell Type RNA - Granulosa cells [nTPM]":"21.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.4","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.6","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"57.9","Single Cell Type RNA - Langerhans cells [nTPM]":"537.6","Single Cell Type RNA - Late spermatids [nTPM]":"8.0","Single Cell Type RNA - Leydig cells [nTPM]":"11.5","Single Cell Type RNA - Macrophages [nTPM]":"123.8","Single Cell Type RNA - Melanocytes [nTPM]":"69.4","Single Cell Type RNA - Microglial cells [nTPM]":"44.0","Single Cell Type RNA - monocytes [nTPM]":"44.1","Single Cell Type RNA - Muller glia cells [nTPM]":"34.4","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"29.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.4","Single Cell Type RNA - Paneth cells [nTPM]":"30.7","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"45.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"28.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"23.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"16.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.9","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"13.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"33.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"65.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"14.0","Single Cell Type RNA - T-cells [nTPM]":"66.5","Single Cell Type RNA - Theca cells [nTPM]":"15.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.7","Single Cell Type RNA - Urothelial cells [nTPM]":"36.2"},{"Gene":"GNAI2","Gene synonym":["GIP","GNAI2B"],"Ensembl":"ENSG00000114353","Gene description":"G protein subunit alpha i2","Uniprot":["P04899"],"Chromosome":"3","Position":"50226292-50259362","Protein class":["Human disease related genes","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division"],"Molecular function":["Transducer"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"656.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007704"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"4000000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA007704":"AB_1849230"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.03e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.40e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.00e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.24e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.30e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"210.2","Tissue RNA - adrenal gland [nTPM]":"100.3","Tissue RNA - amygdala [nTPM]":"155.2","Tissue RNA - appendix [nTPM]":"217.9","Tissue RNA - basal ganglia [nTPM]":"167.3","Tissue RNA - bone marrow [nTPM]":"367.1","Tissue RNA - breast [nTPM]":"152.8","Tissue RNA - cerebellum [nTPM]":"166.3","Tissue RNA - cerebral cortex [nTPM]":"181.6","Tissue RNA - cervix [nTPM]":"146.0","Tissue RNA - choroid plexus [nTPM]":"120.2","Tissue RNA - colon [nTPM]":"142.1","Tissue RNA - duodenum [nTPM]":"69.9","Tissue RNA - endometrium 1 [nTPM]":"141.7","Tissue RNA - epididymis [nTPM]":"66.9","Tissue RNA - esophagus [nTPM]":"124.4","Tissue RNA - fallopian tube [nTPM]":"136.9","Tissue RNA - gallbladder [nTPM]":"152.5","Tissue RNA - heart muscle [nTPM]":"157.1","Tissue RNA - hippocampal formation [nTPM]":"144.3","Tissue RNA - hypothalamus [nTPM]":"184.6","Tissue RNA - kidney [nTPM]":"79.4","Tissue RNA - liver [nTPM]":"126.5","Tissue RNA - lung [nTPM]":"214.5","Tissue RNA - lymph node [nTPM]":"251.3","Tissue RNA - medulla oblongata [nTPM]":"199.8","Tissue RNA - midbrain [nTPM]":"170.2","Tissue RNA - ovary [nTPM]":"147.7","Tissue RNA - pancreas [nTPM]":"64.1","Tissue RNA - parathyroid gland [nTPM]":"66.9","Tissue RNA - pituitary gland [nTPM]":"99.2","Tissue RNA - placenta [nTPM]":"241.8","Tissue RNA - pons [nTPM]":"194.8","Tissue RNA - prostate [nTPM]":"103.6","Tissue RNA - rectum [nTPM]":"64.3","Tissue RNA - retina [nTPM]":"35.6","Tissue RNA - salivary gland [nTPM]":"71.9","Tissue RNA - seminal vesicle [nTPM]":"156.9","Tissue RNA - skeletal muscle [nTPM]":"69.3","Tissue RNA - skin 1 [nTPM]":"87.0","Tissue RNA - small intestine [nTPM]":"103.0","Tissue RNA - smooth muscle [nTPM]":"154.0","Tissue RNA - spinal cord [nTPM]":"173.6","Tissue RNA - spleen [nTPM]":"262.1","Tissue RNA - stomach 1 [nTPM]":"73.6","Tissue RNA - testis [nTPM]":"69.6","Tissue RNA - thalamus [nTPM]":"173.3","Tissue RNA - thymus [nTPM]":"160.3","Tissue RNA - thyroid gland [nTPM]":"101.3","Tissue RNA - tongue [nTPM]":"89.4","Tissue RNA - tonsil [nTPM]":"170.4","Tissue RNA - urinary bladder [nTPM]":"169.7","Tissue RNA - vagina [nTPM]":"108.4","Tissue RNA - white matter [nTPM]":"193.2","Cell RNA - A-431 [nTPM]":"128.2","Cell RNA - A549 [nTPM]":"63.0","Cell RNA - AF22 [nTPM]":"186.3","Cell RNA - AN3-CA [nTPM]":"197.6","Cell RNA - ASC diff [nTPM]":"220.7","Cell RNA - ASC TERT1 [nTPM]":"277.5","Cell RNA - BEWO [nTPM]":"35.5","Cell RNA - BJ [nTPM]":"271.1","Cell RNA - BJ hTERT+ [nTPM]":"399.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"354.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"361.1","Cell RNA - CACO-2 [nTPM]":"70.4","Cell RNA - CAPAN-2 [nTPM]":"173.2","Cell RNA - Daudi [nTPM]":"149.1","Cell RNA - EFO-21 [nTPM]":"119.2","Cell RNA - fHDF\/TERT166 [nTPM]":"567.0","Cell RNA - GAMG [nTPM]":"193.4","Cell RNA - HaCaT [nTPM]":"100.1","Cell RNA - HAP1 [nTPM]":"132.8","Cell RNA - HBEC3-KT [nTPM]":"350.3","Cell RNA - HBF TERT88 [nTPM]":"222.8","Cell RNA - HDLM-2 [nTPM]":"331.2","Cell RNA - HEK 293 [nTPM]":"50.9","Cell RNA - HEL [nTPM]":"364.8","Cell RNA - HeLa [nTPM]":"158.0","Cell RNA - Hep G2 [nTPM]":"110.2","Cell RNA - HHSteC [nTPM]":"219.8","Cell RNA - HL-60 [nTPM]":"329.2","Cell RNA - HMC-1 [nTPM]":"479.8","Cell RNA - HSkMC [nTPM]":"270.3","Cell RNA - hTCEpi [nTPM]":"152.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"319.1","Cell RNA - hTERT-HME1 [nTPM]":"129.8","Cell RNA - hTERT-RPE1 [nTPM]":"289.6","Cell RNA - HUVEC TERT2 [nTPM]":"837.8","Cell RNA - JURKAT [nTPM]":"124.1","Cell RNA - K-562 [nTPM]":"26.1","Cell RNA - Karpas-707 [nTPM]":"307.1","Cell RNA - LHCN-M2 [nTPM]":"357.5","Cell RNA - MCF7 [nTPM]":"155.7","Cell RNA - MOLT-4 [nTPM]":"313.6","Cell RNA - NB-4 [nTPM]":"433.0","Cell RNA - NTERA-2 [nTPM]":"109.7","Cell RNA - OE19 [nTPM]":"59.0","Cell RNA - PC-3 [nTPM]":"302.4","Cell RNA - REH [nTPM]":"185.0","Cell RNA - RH-30 [nTPM]":"89.8","Cell RNA - RPMI-8226 [nTPM]":"219.7","Cell RNA - RPTEC TERT1 [nTPM]":"232.6","Cell RNA - RT4 [nTPM]":"130.9","Cell RNA - SCLC-21H [nTPM]":"48.4","Cell RNA - SH-SY5Y [nTPM]":"86.1","Cell RNA - SiHa [nTPM]":"189.5","Cell RNA - SK-BR-3 [nTPM]":"57.1","Cell RNA - SK-MEL-30 [nTPM]":"124.4","Cell RNA - SuSa [nTPM]":"150.4","Cell RNA - T-47d [nTPM]":"94.3","Cell RNA - THP-1 [nTPM]":"346.1","Cell RNA - TIME [nTPM]":"792.3","Cell RNA - U-138 MG [nTPM]":"330.9","Cell RNA - U-2 OS [nTPM]":"187.5","Cell RNA - U-2197 [nTPM]":"309.2","Cell RNA - U-251 MG [nTPM]":"274.7","Cell RNA - U-266\/70 [nTPM]":"199.4","Cell RNA - U-266\/84 [nTPM]":"278.3","Cell RNA - U-698 [nTPM]":"127.0","Cell RNA - U-87 MG [nTPM]":"373.6","Cell RNA - U-937 [nTPM]":"466.9","Cell RNA - WM-115 [nTPM]":"398.1","Blood RNA - basophil [nTPM]":"16.6","Blood RNA - classical monocyte [nTPM]":"59.3","Blood RNA - eosinophil [nTPM]":"113.7","Blood RNA - gdT-cell [nTPM]":"33.7","Blood RNA - intermediate monocyte [nTPM]":"80.9","Blood RNA - MAIT T-cell [nTPM]":"20.2","Blood RNA - memory B-cell [nTPM]":"28.8","Blood RNA - memory CD4 T-cell [nTPM]":"26.8","Blood RNA - memory CD8 T-cell [nTPM]":"34.3","Blood RNA - myeloid DC [nTPM]":"57.3","Blood RNA - naive B-cell [nTPM]":"26.1","Blood RNA - naive CD4 T-cell [nTPM]":"20.2","Blood RNA - naive CD8 T-cell [nTPM]":"25.8","Blood RNA - neutrophil [nTPM]":"145.2","Blood RNA - NK-cell [nTPM]":"23.5","Blood RNA - non-classical monocyte [nTPM]":"74.5","Blood RNA - plasmacytoid DC [nTPM]":"47.2","Blood RNA - T-reg [nTPM]":"34.0","Blood RNA - total PBMC [nTPM]":"27.3","Brain RNA - amygdala [nTPM]":"155.2","Brain RNA - basal ganglia [nTPM]":"167.3","Brain RNA - cerebellum [nTPM]":"166.3","Brain RNA - cerebral cortex [nTPM]":"181.6","Brain RNA - hippocampal formation [nTPM]":"144.3","Brain RNA - hypothalamus [nTPM]":"184.6","Brain RNA - medulla oblongata [nTPM]":"199.8","Brain RNA - midbrain [nTPM]":"170.2","Brain RNA - pons [nTPM]":"194.8","Brain RNA - spinal cord [nTPM]":"173.6","Brain RNA - thalamus [nTPM]":"173.3","Brain RNA - white matter [nTPM]":"193.2","Single Cell Type RNA - Adipocytes [nTPM]":"656.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.1","Single Cell Type RNA - Astrocytes [nTPM]":"25.1","Single Cell Type RNA - B-cells [nTPM]":"119.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"45.5","Single Cell Type RNA - Bipolar cells [nTPM]":"29.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"83.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"22.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"55.8","Single Cell Type RNA - Club cells [nTPM]":"26.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"79.5","Single Cell Type RNA - dendritic cells [nTPM]":"311.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"124.3","Single Cell Type RNA - Early spermatids [nTPM]":"203.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"57.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"115.7","Single Cell Type RNA - Endothelial cells [nTPM]":"340.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"92.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"60.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.4","Single Cell Type RNA - Fibroblasts [nTPM]":"101.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.8","Single Cell Type RNA - granulocytes [nTPM]":"89.9","Single Cell Type RNA - Granulosa cells [nTPM]":"150.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"221.3","Single Cell Type RNA - Hepatocytes [nTPM]":"79.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"336.0","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.6","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"342.7","Single Cell Type RNA - Langerhans cells [nTPM]":"291.7","Single Cell Type RNA - Late spermatids [nTPM]":"302.0","Single Cell Type RNA - Leydig cells [nTPM]":"90.7","Single Cell Type RNA - Macrophages [nTPM]":"386.1","Single Cell Type RNA - Melanocytes [nTPM]":"83.6","Single Cell Type RNA - Microglial cells [nTPM]":"58.1","Single Cell Type RNA - monocytes [nTPM]":"356.6","Single Cell Type RNA - Muller glia cells [nTPM]":"292.6","Single Cell Type RNA - NK-cells [nTPM]":"151.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"45.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"160.3","Single Cell Type RNA - Paneth cells [nTPM]":"40.9","Single Cell Type RNA - Peritubular cells [nTPM]":"95.5","Single Cell Type RNA - Plasma cells [nTPM]":"104.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"46.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.9","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"85.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"163.1","Single Cell Type RNA - Spermatocytes [nTPM]":"16.6","Single Cell Type RNA - Spermatogonia [nTPM]":"22.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"62.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"116.4","Single Cell Type RNA - T-cells [nTPM]":"164.9","Single Cell Type RNA - Theca cells [nTPM]":"156.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.5","Single Cell Type RNA - Urothelial cells [nTPM]":"70.1"},{"Gene":"GSTP1","Gene synonym":["FAEES3","GST3","GSTP"],"Ensembl":"ENSG00000084207","Gene description":"Glutathione S-transferase pi 1","Uniprot":["P09211"],"Chromosome":"11","Position":"67583742-67586656","Protein class":["Cancer-related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"2087.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Squamous epithelial cells":"4033.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTCEpi":"4998.3","OE19":"7810.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019779","HPA019869"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"69000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 21: OE19 - Mitochondria","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Mitochondria","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA019779":"AB_1849799","HPA019869":"AB_1849801"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.81e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.37e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.78e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.72e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Tissue RNA - adipose tissue [nTPM]":"290.5","Tissue RNA - adrenal gland [nTPM]":"276.2","Tissue RNA - amygdala [nTPM]":"346.8","Tissue RNA - appendix [nTPM]":"232.1","Tissue RNA - basal ganglia [nTPM]":"370.3","Tissue RNA - bone marrow [nTPM]":"601.3","Tissue RNA - breast [nTPM]":"288.7","Tissue RNA - cerebellum [nTPM]":"358.9","Tissue RNA - cerebral cortex [nTPM]":"425.7","Tissue RNA - cervix [nTPM]":"641.9","Tissue RNA - choroid plexus [nTPM]":"695.8","Tissue RNA - colon [nTPM]":"329.6","Tissue RNA - duodenum [nTPM]":"394.6","Tissue RNA - endometrium 1 [nTPM]":"331.9","Tissue RNA - epididymis [nTPM]":"280.3","Tissue RNA - esophagus [nTPM]":"2087.9","Tissue RNA - fallopian tube [nTPM]":"647.5","Tissue RNA - gallbladder [nTPM]":"435.8","Tissue RNA - heart muscle [nTPM]":"367.2","Tissue RNA - hippocampal formation [nTPM]":"341.4","Tissue RNA - hypothalamus [nTPM]":"381.9","Tissue RNA - kidney [nTPM]":"567.7","Tissue RNA - liver [nTPM]":"45.1","Tissue RNA - lung [nTPM]":"468.3","Tissue RNA - lymph node [nTPM]":"321.8","Tissue RNA - medulla oblongata [nTPM]":"375.7","Tissue RNA - midbrain [nTPM]":"379.2","Tissue RNA - ovary [nTPM]":"306.9","Tissue RNA - pancreas [nTPM]":"340.9","Tissue RNA - parathyroid gland [nTPM]":"737.4","Tissue RNA - pituitary gland [nTPM]":"320.2","Tissue RNA - placenta [nTPM]":"326.9","Tissue RNA - pons [nTPM]":"378.5","Tissue RNA - prostate [nTPM]":"291.7","Tissue RNA - rectum [nTPM]":"197.1","Tissue RNA - retina [nTPM]":"137.9","Tissue RNA - salivary gland [nTPM]":"541.2","Tissue RNA - seminal vesicle [nTPM]":"780.4","Tissue RNA - skeletal muscle [nTPM]":"355.0","Tissue RNA - skin 1 [nTPM]":"731.4","Tissue RNA - small intestine [nTPM]":"321.7","Tissue RNA - smooth muscle [nTPM]":"214.2","Tissue RNA - spinal cord [nTPM]":"367.0","Tissue RNA - spleen [nTPM]":"257.2","Tissue RNA - stomach 1 [nTPM]":"535.5","Tissue RNA - testis [nTPM]":"45.8","Tissue RNA - thalamus [nTPM]":"378.1","Tissue RNA - thymus [nTPM]":"296.9","Tissue RNA - thyroid gland [nTPM]":"579.0","Tissue RNA - tongue [nTPM]":"312.5","Tissue RNA - tonsil [nTPM]":"380.8","Tissue RNA - urinary bladder [nTPM]":"526.5","Tissue RNA - vagina [nTPM]":"946.2","Tissue RNA - white matter [nTPM]":"377.7","Cell RNA - A-431 [nTPM]":"1202.5","Cell RNA - A549 [nTPM]":"1599.4","Cell RNA - AF22 [nTPM]":"763.7","Cell RNA - AN3-CA [nTPM]":"1198.9","Cell RNA - ASC diff [nTPM]":"577.8","Cell RNA - ASC TERT1 [nTPM]":"645.2","Cell RNA - BEWO [nTPM]":"705.3","Cell RNA - BJ [nTPM]":"511.3","Cell RNA - BJ hTERT+ [nTPM]":"678.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"761.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"589.3","Cell RNA - CACO-2 [nTPM]":"2956.3","Cell RNA - CAPAN-2 [nTPM]":"1225.0","Cell RNA - Daudi [nTPM]":"3.3","Cell RNA - EFO-21 [nTPM]":"1144.7","Cell RNA - fHDF\/TERT166 [nTPM]":"813.5","Cell RNA - GAMG [nTPM]":"683.7","Cell RNA - HaCaT [nTPM]":"1707.8","Cell RNA - HAP1 [nTPM]":"2073.9","Cell RNA - HBEC3-KT [nTPM]":"2248.5","Cell RNA - HBF TERT88 [nTPM]":"214.4","Cell RNA - HDLM-2 [nTPM]":"848.0","Cell RNA - HEK 293 [nTPM]":"765.3","Cell RNA - HEL [nTPM]":"59.9","Cell RNA - HeLa [nTPM]":"1107.6","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"852.2","Cell RNA - HL-60 [nTPM]":"400.3","Cell RNA - HMC-1 [nTPM]":"667.6","Cell RNA - HSkMC [nTPM]":"807.2","Cell RNA - hTCEpi [nTPM]":"4998.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"609.9","Cell RNA - hTERT-HME1 [nTPM]":"583.3","Cell RNA - hTERT-RPE1 [nTPM]":"560.9","Cell RNA - HUVEC TERT2 [nTPM]":"1160.2","Cell RNA - JURKAT [nTPM]":"847.2","Cell RNA - K-562 [nTPM]":"1318.2","Cell RNA - Karpas-707 [nTPM]":"321.8","Cell RNA - LHCN-M2 [nTPM]":"605.7","Cell RNA - MCF7 [nTPM]":"4.3","Cell RNA - MOLT-4 [nTPM]":"918.2","Cell RNA - NB-4 [nTPM]":"1100.6","Cell RNA - NTERA-2 [nTPM]":"1475.2","Cell RNA - OE19 [nTPM]":"7810.3","Cell RNA - PC-3 [nTPM]":"681.3","Cell RNA - REH [nTPM]":"844.8","Cell RNA - RH-30 [nTPM]":"129.6","Cell RNA - RPMI-8226 [nTPM]":"3.8","Cell RNA - RPTEC TERT1 [nTPM]":"1236.8","Cell RNA - RT4 [nTPM]":"3.6","Cell RNA - SCLC-21H [nTPM]":"260.6","Cell RNA - SH-SY5Y [nTPM]":"754.3","Cell RNA - SiHa [nTPM]":"719.1","Cell RNA - SK-BR-3 [nTPM]":"230.9","Cell RNA - SK-MEL-30 [nTPM]":"2394.0","Cell RNA - SuSa [nTPM]":"598.2","Cell RNA - T-47d [nTPM]":"3.6","Cell RNA - THP-1 [nTPM]":"656.3","Cell RNA - TIME [nTPM]":"634.5","Cell RNA - U-138 MG [nTPM]":"351.6","Cell RNA - U-2 OS [nTPM]":"883.8","Cell RNA - U-2197 [nTPM]":"740.6","Cell RNA - U-251 MG [nTPM]":"378.6","Cell RNA - U-266\/70 [nTPM]":"200.0","Cell RNA - U-266\/84 [nTPM]":"1353.9","Cell RNA - U-698 [nTPM]":"447.1","Cell RNA - U-87 MG [nTPM]":"400.0","Cell RNA - U-937 [nTPM]":"652.4","Cell RNA - WM-115 [nTPM]":"747.8","Blood RNA - basophil [nTPM]":"56.0","Blood RNA - classical monocyte [nTPM]":"3145.4","Blood RNA - eosinophil [nTPM]":"246.6","Blood RNA - gdT-cell [nTPM]":"720.0","Blood RNA - intermediate monocyte [nTPM]":"2470.8","Blood RNA - MAIT T-cell [nTPM]":"271.9","Blood RNA - memory B-cell [nTPM]":"509.2","Blood RNA - memory CD4 T-cell [nTPM]":"322.4","Blood RNA - memory CD8 T-cell [nTPM]":"597.7","Blood RNA - myeloid DC [nTPM]":"3582.7","Blood RNA - naive B-cell [nTPM]":"476.3","Blood RNA - naive CD4 T-cell [nTPM]":"267.8","Blood RNA - naive CD8 T-cell [nTPM]":"466.5","Blood RNA - neutrophil [nTPM]":"130.5","Blood RNA - NK-cell [nTPM]":"1443.8","Blood RNA - non-classical monocyte [nTPM]":"1608.5","Blood RNA - plasmacytoid DC [nTPM]":"1435.1","Blood RNA - T-reg [nTPM]":"363.3","Blood RNA - total PBMC [nTPM]":"3948.4","Brain RNA - amygdala [nTPM]":"346.8","Brain RNA - basal ganglia [nTPM]":"370.3","Brain RNA - cerebellum [nTPM]":"358.9","Brain RNA - cerebral cortex [nTPM]":"425.7","Brain RNA - hippocampal formation [nTPM]":"341.4","Brain RNA - hypothalamus [nTPM]":"381.9","Brain RNA - medulla oblongata [nTPM]":"375.7","Brain RNA - midbrain [nTPM]":"379.2","Brain RNA - pons [nTPM]":"378.5","Brain RNA - spinal cord [nTPM]":"367.0","Brain RNA - thalamus [nTPM]":"378.1","Brain RNA - white matter [nTPM]":"377.7","Single Cell Type RNA - Adipocytes [nTPM]":"466.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"1153.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"872.3","Single Cell Type RNA - Astrocytes [nTPM]":"25.5","Single Cell Type RNA - B-cells [nTPM]":"296.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"865.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1914.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3813.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"767.2","Single Cell Type RNA - Bipolar cells [nTPM]":"170.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"628.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"838.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"297.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"987.9","Single Cell Type RNA - Club cells [nTPM]":"2763.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1230.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2116.8","Single Cell Type RNA - dendritic cells [nTPM]":"372.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"655.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1805.9","Single Cell Type RNA - Ductal cells [nTPM]":"1811.9","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1381.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"589.0","Single Cell Type RNA - Endothelial cells [nTPM]":"431.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"368.2","Single Cell Type RNA - Erythroid cells [nTPM]":"166.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"6.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1444.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1703.9","Single Cell Type RNA - Fibroblasts [nTPM]":"710.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"781.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1020.9","Single Cell Type RNA - granulocytes [nTPM]":"269.9","Single Cell Type RNA - Granulosa cells [nTPM]":"795.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"382.3","Single Cell Type RNA - Hepatocytes [nTPM]":"10.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"861.2","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"992.4","Single Cell Type RNA - Ionocytes [nTPM]":"1930.7","Single Cell Type RNA - Kupffer cells [nTPM]":"597.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1090.3","Single Cell Type RNA - Late spermatids [nTPM]":"25.5","Single Cell Type RNA - Leydig cells [nTPM]":"572.3","Single Cell Type RNA - Macrophages [nTPM]":"703.5","Single Cell Type RNA - Melanocytes [nTPM]":"1531.5","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"2166.5","Single Cell Type RNA - Muller glia cells [nTPM]":"558.5","Single Cell Type RNA - NK-cells [nTPM]":"459.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"38.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1412.1","Single Cell Type RNA - Paneth cells [nTPM]":"948.9","Single Cell Type RNA - Peritubular cells [nTPM]":"400.2","Single Cell Type RNA - Plasma cells [nTPM]":"591.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2266.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"844.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3495.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3715.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"274.4","Single Cell Type RNA - Sertoli cells [nTPM]":"361.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"401.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"941.7","Single Cell Type RNA - Spermatocytes [nTPM]":"4.8","Single Cell Type RNA - Spermatogonia [nTPM]":"54.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4033.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1061.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1645.5","Single Cell Type RNA - T-cells [nTPM]":"342.5","Single Cell Type RNA - Theca cells [nTPM]":"527.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1118.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3418.6"},{"Gene":"HGF","Gene synonym":["DFNB39","F-TCF","HGFB","HPTA","SF"],"Ensembl":"ENSG00000019991","Gene description":"Hepatocyte growth factor","Uniprot":["P14210"],"Chromosome":"7","Position":"81699010-81770438","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor","Serine protease homolog"],"Disease involvement":["Cancer-related genes","Deafness","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"10","RNA tissue specific nTPM":{"placenta":"311.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"23.8","Fibroblasts":"95.8","Hepatic stellate cells":"25.0","Muller glia cells":"36.2","Smooth muscle cells":"26.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"94.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"94.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"171.6","HHSteC":"135.8","HL-60":"82.4","hTEC\/SVTERT24-B":"87.4","Karpas-707":"240.7","U-87 MG":"62.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010333","HPA040360","HPA044088"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4110000,"Blood concentration - Conc. blood MS [pg\/L]":"14000","Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010333":"AB_647965","HPA040360":"AB_2676939","HPA044088":"AB_2678804"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.77e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.97e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.59e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.9","Tissue RNA - adrenal gland [nTPM]":"19.8","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"3.3","Tissue RNA - bone marrow [nTPM]":"12.3","Tissue RNA - breast [nTPM]":"5.2","Tissue RNA - cerebellum [nTPM]":"1.5","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"7.2","Tissue RNA - choroid plexus [nTPM]":"1.8","Tissue RNA - colon [nTPM]":"4.4","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"8.1","Tissue RNA - epididymis [nTPM]":"3.6","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"5.4","Tissue RNA - gallbladder [nTPM]":"16.6","Tissue RNA - heart muscle [nTPM]":"4.7","Tissue RNA - hippocampal formation [nTPM]":"2.9","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"30.3","Tissue RNA - lung [nTPM]":"19.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"3.6","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"1.8","Tissue RNA - pancreas [nTPM]":"2.1","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"2.4","Tissue RNA - placenta [nTPM]":"311.9","Tissue RNA - pons [nTPM]":"4.3","Tissue RNA - prostate [nTPM]":"7.2","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"6.4","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"2.3","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"6.5","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"1.5","Tissue RNA - thyroid gland [nTPM]":"5.6","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"6.3","Tissue RNA - white matter [nTPM]":"3.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"21.6","Cell RNA - ASC TERT1 [nTPM]":"171.6","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"33.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.8","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"6.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"135.8","Cell RNA - HL-60 [nTPM]":"82.4","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"41.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"87.4","Cell RNA - hTERT-HME1 [nTPM]":"0.3","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"2.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"240.7","Cell RNA - LHCN-M2 [nTPM]":"0.6","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"56.4","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"9.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"2.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"62.6","Cell RNA - U-937 [nTPM]":"16.9","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"94.0","Blood RNA - classical monocyte [nTPM]":"15.2","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"18.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"4.8","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"3.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"17.3","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"4.3","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"3.3","Brain RNA - cerebellum [nTPM]":"1.5","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"2.9","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"3.6","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"4.3","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.3","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"4.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"15.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.8","Single Cell Type RNA - Endothelial cells [nTPM]":"6.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"2.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"4.9","Single Cell Type RNA - Fibroblasts [nTPM]":"95.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.9","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.5","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.3","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"14.0","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"10.5","Single Cell Type RNA - Muller glia cells [nTPM]":"36.2","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"26.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"0.6","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"HIF1A","Gene synonym":["bHLHe78","HIF-1alpha","HIF1","MOP1","PASD8"],"Ensembl":"ENSG00000100644","Gene description":"Hypoxia inducible factor 1 subunit alpha","Uniprot":["Q16665"],"Chromosome":"14","Position":"61695513-61748259","Protein class":["Cancer-related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"448.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"155.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"155.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"LHCN-M2":"941.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000907","HPA001275","CAB017442"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB017442":"AB_10621732","HPA000907":"AB_2666139","HPA001275":"AB_1079057"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.39e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.58e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Tissue RNA - adipose tissue [nTPM]":"64.9","Tissue RNA - adrenal gland [nTPM]":"133.7","Tissue RNA - amygdala [nTPM]":"22.1","Tissue RNA - appendix [nTPM]":"146.6","Tissue RNA - basal ganglia [nTPM]":"24.0","Tissue RNA - bone marrow [nTPM]":"448.3","Tissue RNA - breast [nTPM]":"36.2","Tissue RNA - cerebellum [nTPM]":"28.2","Tissue RNA - cerebral cortex [nTPM]":"26.1","Tissue RNA - cervix [nTPM]":"132.9","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"42.8","Tissue RNA - duodenum [nTPM]":"33.6","Tissue RNA - endometrium 1 [nTPM]":"52.4","Tissue RNA - epididymis [nTPM]":"74.8","Tissue RNA - esophagus [nTPM]":"62.1","Tissue RNA - fallopian tube [nTPM]":"41.1","Tissue RNA - gallbladder [nTPM]":"145.4","Tissue RNA - heart muscle [nTPM]":"36.5","Tissue RNA - hippocampal formation [nTPM]":"21.1","Tissue RNA - hypothalamus [nTPM]":"28.4","Tissue RNA - kidney [nTPM]":"104.2","Tissue RNA - liver [nTPM]":"51.6","Tissue RNA - lung [nTPM]":"75.7","Tissue RNA - lymph node [nTPM]":"71.4","Tissue RNA - medulla oblongata [nTPM]":"29.7","Tissue RNA - midbrain [nTPM]":"29.7","Tissue RNA - ovary [nTPM]":"35.3","Tissue RNA - pancreas [nTPM]":"36.0","Tissue RNA - parathyroid gland [nTPM]":"91.7","Tissue RNA - pituitary gland [nTPM]":"30.7","Tissue RNA - placenta [nTPM]":"77.6","Tissue RNA - pons [nTPM]":"33.3","Tissue RNA - prostate [nTPM]":"46.9","Tissue RNA - rectum [nTPM]":"41.7","Tissue RNA - retina [nTPM]":"35.5","Tissue RNA - salivary gland [nTPM]":"45.3","Tissue RNA - seminal vesicle [nTPM]":"67.2","Tissue RNA - skeletal muscle [nTPM]":"12.1","Tissue RNA - skin 1 [nTPM]":"34.2","Tissue RNA - small intestine [nTPM]":"37.3","Tissue RNA - smooth muscle [nTPM]":"59.1","Tissue RNA - spinal cord [nTPM]":"27.2","Tissue RNA - spleen [nTPM]":"72.4","Tissue RNA - stomach 1 [nTPM]":"37.6","Tissue RNA - testis [nTPM]":"32.4","Tissue RNA - thalamus [nTPM]":"38.5","Tissue RNA - thymus [nTPM]":"55.8","Tissue RNA - thyroid gland [nTPM]":"49.5","Tissue RNA - tongue [nTPM]":"17.6","Tissue RNA - tonsil [nTPM]":"88.2","Tissue RNA - urinary bladder [nTPM]":"169.9","Tissue RNA - vagina [nTPM]":"43.1","Tissue RNA - white matter [nTPM]":"26.5","Cell RNA - A-431 [nTPM]":"313.6","Cell RNA - A549 [nTPM]":"123.6","Cell RNA - AF22 [nTPM]":"112.7","Cell RNA - AN3-CA [nTPM]":"344.7","Cell RNA - ASC diff [nTPM]":"185.2","Cell RNA - ASC TERT1 [nTPM]":"297.1","Cell RNA - BEWO [nTPM]":"161.5","Cell RNA - BJ [nTPM]":"253.8","Cell RNA - BJ hTERT+ [nTPM]":"270.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"288.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"258.9","Cell RNA - CACO-2 [nTPM]":"54.1","Cell RNA - CAPAN-2 [nTPM]":"100.3","Cell RNA - Daudi [nTPM]":"75.8","Cell RNA - EFO-21 [nTPM]":"186.2","Cell RNA - fHDF\/TERT166 [nTPM]":"293.0","Cell RNA - GAMG [nTPM]":"73.6","Cell RNA - HaCaT [nTPM]":"71.8","Cell RNA - HAP1 [nTPM]":"71.0","Cell RNA - HBEC3-KT [nTPM]":"416.1","Cell RNA - HBF TERT88 [nTPM]":"352.5","Cell RNA - HDLM-2 [nTPM]":"33.7","Cell RNA - HEK 293 [nTPM]":"41.0","Cell RNA - HEL [nTPM]":"46.5","Cell RNA - HeLa [nTPM]":"105.3","Cell RNA - Hep G2 [nTPM]":"93.1","Cell RNA - HHSteC [nTPM]":"414.8","Cell RNA - HL-60 [nTPM]":"20.1","Cell RNA - HMC-1 [nTPM]":"49.3","Cell RNA - HSkMC [nTPM]":"523.4","Cell RNA - hTCEpi [nTPM]":"129.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"216.5","Cell RNA - hTERT-HME1 [nTPM]":"225.6","Cell RNA - hTERT-RPE1 [nTPM]":"408.6","Cell RNA - HUVEC TERT2 [nTPM]":"198.1","Cell RNA - JURKAT [nTPM]":"44.4","Cell RNA - K-562 [nTPM]":"32.3","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"941.4","Cell RNA - MCF7 [nTPM]":"65.6","Cell RNA - MOLT-4 [nTPM]":"59.2","Cell RNA - NB-4 [nTPM]":"24.3","Cell RNA - NTERA-2 [nTPM]":"108.9","Cell RNA - OE19 [nTPM]":"49.6","Cell RNA - PC-3 [nTPM]":"159.7","Cell RNA - REH [nTPM]":"4.3","Cell RNA - RH-30 [nTPM]":"269.1","Cell RNA - RPMI-8226 [nTPM]":"22.8","Cell RNA - RPTEC TERT1 [nTPM]":"400.2","Cell RNA - RT4 [nTPM]":"204.3","Cell RNA - SCLC-21H [nTPM]":"100.3","Cell RNA - SH-SY5Y [nTPM]":"111.9","Cell RNA - SiHa [nTPM]":"472.5","Cell RNA - SK-BR-3 [nTPM]":"67.0","Cell RNA - SK-MEL-30 [nTPM]":"170.7","Cell RNA - SuSa [nTPM]":"148.9","Cell RNA - T-47d [nTPM]":"70.6","Cell RNA - THP-1 [nTPM]":"36.3","Cell RNA - TIME [nTPM]":"119.2","Cell RNA - U-138 MG [nTPM]":"700.2","Cell RNA - U-2 OS [nTPM]":"157.3","Cell RNA - U-2197 [nTPM]":"235.9","Cell RNA - U-251 MG [nTPM]":"215.2","Cell RNA - U-266\/70 [nTPM]":"39.1","Cell RNA - U-266\/84 [nTPM]":"61.2","Cell RNA - U-698 [nTPM]":"84.1","Cell RNA - U-87 MG [nTPM]":"369.9","Cell RNA - U-937 [nTPM]":"38.5","Cell RNA - WM-115 [nTPM]":"194.7","Blood RNA - basophil [nTPM]":"43.8","Blood RNA - classical monocyte [nTPM]":"22.3","Blood RNA - eosinophil [nTPM]":"155.0","Blood RNA - gdT-cell [nTPM]":"11.5","Blood RNA - intermediate monocyte [nTPM]":"18.0","Blood RNA - MAIT T-cell [nTPM]":"14.4","Blood RNA - memory B-cell [nTPM]":"19.5","Blood RNA - memory CD4 T-cell [nTPM]":"15.0","Blood RNA - memory CD8 T-cell [nTPM]":"13.3","Blood RNA - myeloid DC [nTPM]":"19.6","Blood RNA - naive B-cell [nTPM]":"19.0","Blood RNA - naive CD4 T-cell [nTPM]":"22.6","Blood RNA - naive CD8 T-cell [nTPM]":"15.6","Blood RNA - neutrophil [nTPM]":"56.3","Blood RNA - NK-cell [nTPM]":"19.7","Blood RNA - non-classical monocyte [nTPM]":"19.4","Blood RNA - plasmacytoid DC [nTPM]":"9.2","Blood RNA - T-reg [nTPM]":"11.0","Blood RNA - total PBMC [nTPM]":"18.4","Brain RNA - amygdala [nTPM]":"22.1","Brain RNA - basal ganglia [nTPM]":"24.0","Brain RNA - cerebellum [nTPM]":"28.2","Brain RNA - cerebral cortex [nTPM]":"26.1","Brain RNA - hippocampal formation [nTPM]":"21.1","Brain RNA - hypothalamus [nTPM]":"28.4","Brain RNA - medulla oblongata [nTPM]":"29.7","Brain RNA - midbrain [nTPM]":"29.7","Brain RNA - pons [nTPM]":"33.3","Brain RNA - spinal cord [nTPM]":"27.2","Brain RNA - thalamus [nTPM]":"38.5","Brain RNA - white matter [nTPM]":"26.5","Single Cell Type RNA - Adipocytes [nTPM]":"93.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"116.0","Single Cell Type RNA - Astrocytes [nTPM]":"69.2","Single Cell Type RNA - B-cells [nTPM]":"157.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"106.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"101.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"97.9","Single Cell Type RNA - Bipolar cells [nTPM]":"54.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"87.2","Single Cell Type RNA - Club cells [nTPM]":"69.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"261.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"50.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"24.8","Single Cell Type RNA - dendritic cells [nTPM]":"65.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"103.7","Single Cell Type RNA - Ductal cells [nTPM]":"278.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"95.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"131.3","Single Cell Type RNA - Endothelial cells [nTPM]":"152.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.4","Single Cell Type RNA - Erythroid cells [nTPM]":"35.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"45.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"251.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"67.1","Single Cell Type RNA - Fibroblasts [nTPM]":"81.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"49.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"272.3","Single Cell Type RNA - granulocytes [nTPM]":"223.6","Single Cell Type RNA - Granulosa cells [nTPM]":"339.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"176.0","Single Cell Type RNA - Hepatocytes [nTPM]":"30.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"136.4","Single Cell Type RNA - Horizontal cells [nTPM]":"156.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"39.0","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"145.9","Single Cell Type RNA - Langerhans cells [nTPM]":"111.7","Single Cell Type RNA - Late spermatids [nTPM]":"6.2","Single Cell Type RNA - Leydig cells [nTPM]":"24.2","Single Cell Type RNA - Macrophages [nTPM]":"240.2","Single Cell Type RNA - Melanocytes [nTPM]":"103.2","Single Cell Type RNA - Microglial cells [nTPM]":"53.4","Single Cell Type RNA - monocytes [nTPM]":"87.1","Single Cell Type RNA - Muller glia cells [nTPM]":"134.0","Single Cell Type RNA - NK-cells [nTPM]":"26.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"78.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"35.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"236.9","Single Cell Type RNA - Paneth cells [nTPM]":"21.9","Single Cell Type RNA - Peritubular cells [nTPM]":"48.5","Single Cell Type RNA - Plasma cells [nTPM]":"60.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"59.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"20.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"192.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"54.8","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"75.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"136.9","Single Cell Type RNA - Spermatocytes [nTPM]":"80.5","Single Cell Type RNA - Spermatogonia [nTPM]":"44.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"128.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"87.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"25.4","Single Cell Type RNA - T-cells [nTPM]":"91.6","Single Cell Type RNA - Theca cells [nTPM]":"92.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.8","Single Cell Type RNA - Urothelial cells [nTPM]":"116.0"},{"Gene":"HLA-DRB5","Gene synonym":[],"Ensembl":"ENSG00000198502","Gene description":"Major histocompatibility complex, class II, DR beta 5","Uniprot":["Q30154"],"Chromosome":"6","Position":"32517353-32530287","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Immunity"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lung":"356.2","lymphoid tissue":"423.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Langerhans cells":"4068.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"myeloid DC":"61.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"B-cells":"26.1","dendritic cells":"61.9","monocytes":"35.2"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"641.1","HMC-1":"154.2","U-698":"189.9","U-87 MG":"238.6"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043151"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Myeloid DCs - Unknown function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043151":"AB_2678342"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.89e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.28e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.09e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.60e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.72e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"110.0","Tissue RNA - adrenal gland [nTPM]":"63.0","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"138.9","Tissue RNA - basal ganglia [nTPM]":"1.4","Tissue RNA - bone marrow [nTPM]":"23.0","Tissue RNA - breast [nTPM]":"82.6","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"53.8","Tissue RNA - choroid plexus [nTPM]":"2.9","Tissue RNA - colon [nTPM]":"70.1","Tissue RNA - duodenum [nTPM]":"13.1","Tissue RNA - endometrium 1 [nTPM]":"39.7","Tissue RNA - epididymis [nTPM]":"109.8","Tissue RNA - esophagus [nTPM]":"48.6","Tissue RNA - fallopian tube [nTPM]":"61.0","Tissue RNA - gallbladder [nTPM]":"2.5","Tissue RNA - heart muscle [nTPM]":"48.0","Tissue RNA - hippocampal formation [nTPM]":"0.9","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"66.6","Tissue RNA - liver [nTPM]":"42.6","Tissue RNA - lung [nTPM]":"356.2","Tissue RNA - lymph node [nTPM]":"423.3","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"25.4","Tissue RNA - pancreas [nTPM]":"27.9","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"27.2","Tissue RNA - placenta [nTPM]":"6.6","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"32.6","Tissue RNA - rectum [nTPM]":"52.9","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"27.6","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"22.3","Tissue RNA - skin 1 [nTPM]":"47.9","Tissue RNA - small intestine [nTPM]":"184.7","Tissue RNA - smooth muscle [nTPM]":"0.2","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"228.4","Tissue RNA - stomach 1 [nTPM]":"214.2","Tissue RNA - testis [nTPM]":"11.8","Tissue RNA - thalamus [nTPM]":"3.2","Tissue RNA - thymus [nTPM]":"165.8","Tissue RNA - thyroid gland [nTPM]":"46.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"162.8","Tissue RNA - urinary bladder [nTPM]":"56.2","Tissue RNA - vagina [nTPM]":"28.9","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"3.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.7","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"641.1","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"154.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"1.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"3.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.4","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"6.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"56.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"3.3","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"1.9","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"41.4","Cell RNA - U-266\/84 [nTPM]":"0.8","Cell RNA - U-698 [nTPM]":"189.9","Cell RNA - U-87 MG [nTPM]":"238.6","Cell RNA - U-937 [nTPM]":"1.8","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"28.6","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"35.2","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"23.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.4","Blood RNA - myeloid DC [nTPM]":"61.9","Blood RNA - naive B-cell [nTPM]":"26.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"1.1","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"2.1","Blood RNA - non-classical monocyte [nTPM]":"20.3","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"51.9","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.4","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"0.9","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"3.2","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"467.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"84.9","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"632.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"104.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"88.6","Single Cell Type RNA - Club cells [nTPM]":"35.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"140.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"2.8","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.1","Single Cell Type RNA - Endothelial cells [nTPM]":"285.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"72.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.9","Single Cell Type RNA - Fibroblasts [nTPM]":"30.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"75.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"60.1","Single Cell Type RNA - Granulosa cells [nTPM]":"1.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"88.5","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"475.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"35.4","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"516.2","Single Cell Type RNA - Langerhans cells [nTPM]":"4068.5","Single Cell Type RNA - Late spermatids [nTPM]":"7.4","Single Cell Type RNA - Leydig cells [nTPM]":"15.8","Single Cell Type RNA - Macrophages [nTPM]":"978.8","Single Cell Type RNA - Melanocytes [nTPM]":"120.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"246.9","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.5","Single Cell Type RNA - Paneth cells [nTPM]":"52.3","Single Cell Type RNA - Peritubular cells [nTPM]":"34.3","Single Cell Type RNA - Plasma cells [nTPM]":"46.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"661.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"37.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"71.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"90.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.1","Single Cell Type RNA - T-cells [nTPM]":"68.0","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.8","Single Cell Type RNA - Urothelial cells [nTPM]":"65.7"},{"Gene":"HRAS","Gene synonym":["HRAS1"],"Ensembl":"ENSG00000174775","Gene description":"HRas proto-oncogene, GTPase","Uniprot":["P01112"],"Chromosome":"11","Position":"532242-537287","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Suprabasal keratinocytes":"145.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"4.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002015","HPA049830","HPA070222"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB002015":null,"HPA049830":"AB_2680903","HPA070222":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.49e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.87e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.32e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Tissue RNA - adipose tissue [nTPM]":"28.1","Tissue RNA - adrenal gland [nTPM]":"24.6","Tissue RNA - amygdala [nTPM]":"64.6","Tissue RNA - appendix [nTPM]":"3.5","Tissue RNA - basal ganglia [nTPM]":"67.2","Tissue RNA - bone marrow [nTPM]":"2.9","Tissue RNA - breast [nTPM]":"27.0","Tissue RNA - cerebellum [nTPM]":"62.1","Tissue RNA - cerebral cortex [nTPM]":"86.8","Tissue RNA - cervix [nTPM]":"30.4","Tissue RNA - choroid plexus [nTPM]":"58.3","Tissue RNA - colon [nTPM]":"34.3","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"23.6","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"80.1","Tissue RNA - fallopian tube [nTPM]":"18.9","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"56.8","Tissue RNA - hippocampal formation [nTPM]":"64.4","Tissue RNA - hypothalamus [nTPM]":"64.6","Tissue RNA - kidney [nTPM]":"33.8","Tissue RNA - liver [nTPM]":"21.8","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"4.3","Tissue RNA - medulla oblongata [nTPM]":"65.6","Tissue RNA - midbrain [nTPM]":"65.3","Tissue RNA - ovary [nTPM]":"20.0","Tissue RNA - pancreas [nTPM]":"20.5","Tissue RNA - parathyroid gland [nTPM]":"13.1","Tissue RNA - pituitary gland [nTPM]":"38.2","Tissue RNA - placenta [nTPM]":"9.0","Tissue RNA - pons [nTPM]":"66.9","Tissue RNA - prostate [nTPM]":"38.3","Tissue RNA - rectum [nTPM]":"6.9","Tissue RNA - retina [nTPM]":"10.2","Tissue RNA - salivary gland [nTPM]":"27.3","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"59.0","Tissue RNA - skin 1 [nTPM]":"69.9","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"64.2","Tissue RNA - spleen [nTPM]":"20.6","Tissue RNA - stomach 1 [nTPM]":"24.2","Tissue RNA - testis [nTPM]":"16.5","Tissue RNA - thalamus [nTPM]":"64.8","Tissue RNA - thymus [nTPM]":"9.2","Tissue RNA - thyroid gland [nTPM]":"20.5","Tissue RNA - tongue [nTPM]":"25.2","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"34.5","Tissue RNA - vagina [nTPM]":"44.2","Tissue RNA - white matter [nTPM]":"65.4","Cell RNA - A-431 [nTPM]":"59.0","Cell RNA - A549 [nTPM]":"105.6","Cell RNA - AF22 [nTPM]":"44.2","Cell RNA - AN3-CA [nTPM]":"25.6","Cell RNA - ASC diff [nTPM]":"22.2","Cell RNA - ASC TERT1 [nTPM]":"17.5","Cell RNA - BEWO [nTPM]":"39.6","Cell RNA - BJ [nTPM]":"49.9","Cell RNA - BJ hTERT+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"29.5","Cell RNA - CACO-2 [nTPM]":"62.4","Cell RNA - CAPAN-2 [nTPM]":"29.7","Cell RNA - Daudi [nTPM]":"20.4","Cell RNA - EFO-21 [nTPM]":"10.9","Cell RNA - fHDF\/TERT166 [nTPM]":"63.2","Cell RNA - GAMG [nTPM]":"60.7","Cell RNA - HaCaT [nTPM]":"43.7","Cell RNA - HAP1 [nTPM]":"46.0","Cell RNA - HBEC3-KT [nTPM]":"114.1","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"19.5","Cell RNA - HEK 293 [nTPM]":"108.4","Cell RNA - HEL [nTPM]":"6.6","Cell RNA - HeLa [nTPM]":"43.7","Cell RNA - Hep G2 [nTPM]":"56.1","Cell RNA - HHSteC [nTPM]":"38.5","Cell RNA - HL-60 [nTPM]":"13.9","Cell RNA - HMC-1 [nTPM]":"12.0","Cell RNA - HSkMC [nTPM]":"28.3","Cell RNA - hTCEpi [nTPM]":"118.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.0","Cell RNA - hTERT-HME1 [nTPM]":"51.5","Cell RNA - hTERT-RPE1 [nTPM]":"19.6","Cell RNA - HUVEC TERT2 [nTPM]":"31.5","Cell RNA - JURKAT [nTPM]":"34.3","Cell RNA - K-562 [nTPM]":"29.7","Cell RNA - Karpas-707 [nTPM]":"32.3","Cell RNA - LHCN-M2 [nTPM]":"40.9","Cell RNA - MCF7 [nTPM]":"110.6","Cell RNA - MOLT-4 [nTPM]":"34.0","Cell RNA - NB-4 [nTPM]":"50.5","Cell RNA - NTERA-2 [nTPM]":"26.5","Cell RNA - OE19 [nTPM]":"39.9","Cell RNA - PC-3 [nTPM]":"94.5","Cell RNA - REH [nTPM]":"31.6","Cell RNA - RH-30 [nTPM]":"40.7","Cell RNA - RPMI-8226 [nTPM]":"18.2","Cell RNA - RPTEC TERT1 [nTPM]":"47.0","Cell RNA - RT4 [nTPM]":"33.2","Cell RNA - SCLC-21H [nTPM]":"87.6","Cell RNA - SH-SY5Y [nTPM]":"43.7","Cell RNA - SiHa [nTPM]":"25.5","Cell RNA - SK-BR-3 [nTPM]":"55.4","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"31.5","Cell RNA - T-47d [nTPM]":"43.3","Cell RNA - THP-1 [nTPM]":"14.8","Cell RNA - TIME [nTPM]":"35.4","Cell RNA - U-138 MG [nTPM]":"47.3","Cell RNA - U-2 OS [nTPM]":"44.7","Cell RNA - U-2197 [nTPM]":"16.4","Cell RNA - U-251 MG [nTPM]":"39.7","Cell RNA - U-266\/70 [nTPM]":"20.3","Cell RNA - U-266\/84 [nTPM]":"17.7","Cell RNA - U-698 [nTPM]":"15.4","Cell RNA - U-87 MG [nTPM]":"39.1","Cell RNA - U-937 [nTPM]":"17.0","Cell RNA - WM-115 [nTPM]":"38.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"0.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"0.7","Blood RNA - naive B-cell [nTPM]":"2.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"4.0","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"1.5","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"64.6","Brain RNA - basal ganglia [nTPM]":"67.2","Brain RNA - cerebellum [nTPM]":"62.1","Brain RNA - cerebral cortex [nTPM]":"86.8","Brain RNA - hippocampal formation [nTPM]":"64.4","Brain RNA - hypothalamus [nTPM]":"64.6","Brain RNA - medulla oblongata [nTPM]":"65.6","Brain RNA - midbrain [nTPM]":"65.3","Brain RNA - pons [nTPM]":"66.9","Brain RNA - spinal cord [nTPM]":"64.2","Brain RNA - thalamus [nTPM]":"64.8","Brain RNA - white matter [nTPM]":"65.4","Single Cell Type RNA - Adipocytes [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.7","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"18.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"131.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"101.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"82.0","Single Cell Type RNA - Bipolar cells [nTPM]":"46.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"38.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"75.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"25.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"11.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"78.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"72.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"74.3","Single Cell Type RNA - Ductal cells [nTPM]":"35.2","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"36.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"28.6","Single Cell Type RNA - Endothelial cells [nTPM]":"32.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"29.3","Single Cell Type RNA - Erythroid cells [nTPM]":"11.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"37.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"63.4","Single Cell Type RNA - Fibroblasts [nTPM]":"25.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"33.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.1","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"26.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.9","Single Cell Type RNA - Hepatocytes [nTPM]":"17.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.9","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.5","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.7","Single Cell Type RNA - Langerhans cells [nTPM]":"38.4","Single Cell Type RNA - Late spermatids [nTPM]":"7.9","Single Cell Type RNA - Leydig cells [nTPM]":"17.1","Single Cell Type RNA - Macrophages [nTPM]":"21.3","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"12.8","Single Cell Type RNA - Muller glia cells [nTPM]":"50.8","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"12.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"48.2","Single Cell Type RNA - Paneth cells [nTPM]":"30.9","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"26.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"54.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.6","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.4","Single Cell Type RNA - Spermatogonia [nTPM]":"21.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"118.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"145.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"78.1","Single Cell Type RNA - T-cells [nTPM]":"22.0","Single Cell Type RNA - Theca cells [nTPM]":"18.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"26.2","Single Cell Type RNA - Urothelial cells [nTPM]":"106.4"},{"Gene":"IDH1","Gene synonym":[],"Ensembl":"ENSG00000138413","Gene description":"Isocitrate dehydrogenase (NADP(+)) 1","Uniprot":["O75874"],"Chromosome":"2","Position":"208236229-208266074","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Glyoxylate bypass","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"536.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"320.2","Granulosa cells":"257.5","Hepatocytes":"328.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Hep G2":"768.1","RT4":"524.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB033218","HPA035248","HPA057936","CAB062556"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"16000000","Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 37: Hep G2 - Hepatocyte cell processes","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nuclear bodies","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB033218":"AB_2123166","CAB062556":"AB_2665593","HPA035248":"AB_10600714","HPA057936":"AB_2683559"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.93e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.18e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.45e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Tissue RNA - adipose tissue [nTPM]":"150.8","Tissue RNA - adrenal gland [nTPM]":"230.8","Tissue RNA - amygdala [nTPM]":"24.0","Tissue RNA - appendix [nTPM]":"37.5","Tissue RNA - basal ganglia [nTPM]":"23.9","Tissue RNA - bone marrow [nTPM]":"10.7","Tissue RNA - breast [nTPM]":"63.0","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"30.9","Tissue RNA - cervix [nTPM]":"67.9","Tissue RNA - choroid plexus [nTPM]":"40.8","Tissue RNA - colon [nTPM]":"124.9","Tissue RNA - duodenum [nTPM]":"179.4","Tissue RNA - endometrium 1 [nTPM]":"22.9","Tissue RNA - epididymis [nTPM]":"164.9","Tissue RNA - esophagus [nTPM]":"92.2","Tissue RNA - fallopian tube [nTPM]":"36.6","Tissue RNA - gallbladder [nTPM]":"69.5","Tissue RNA - heart muscle [nTPM]":"25.3","Tissue RNA - hippocampal formation [nTPM]":"23.5","Tissue RNA - hypothalamus [nTPM]":"26.1","Tissue RNA - kidney [nTPM]":"122.0","Tissue RNA - liver [nTPM]":"536.3","Tissue RNA - lung [nTPM]":"49.8","Tissue RNA - lymph node [nTPM]":"33.3","Tissue RNA - medulla oblongata [nTPM]":"26.4","Tissue RNA - midbrain [nTPM]":"25.7","Tissue RNA - ovary [nTPM]":"84.4","Tissue RNA - pancreas [nTPM]":"39.9","Tissue RNA - parathyroid gland [nTPM]":"42.0","Tissue RNA - pituitary gland [nTPM]":"16.7","Tissue RNA - placenta [nTPM]":"82.5","Tissue RNA - pons [nTPM]":"25.9","Tissue RNA - prostate [nTPM]":"214.6","Tissue RNA - rectum [nTPM]":"131.2","Tissue RNA - retina [nTPM]":"35.0","Tissue RNA - salivary gland [nTPM]":"59.3","Tissue RNA - seminal vesicle [nTPM]":"79.1","Tissue RNA - skeletal muscle [nTPM]":"25.7","Tissue RNA - skin 1 [nTPM]":"23.6","Tissue RNA - small intestine [nTPM]":"117.4","Tissue RNA - smooth muscle [nTPM]":"43.8","Tissue RNA - spinal cord [nTPM]":"25.5","Tissue RNA - spleen [nTPM]":"40.1","Tissue RNA - stomach 1 [nTPM]":"113.6","Tissue RNA - testis [nTPM]":"57.0","Tissue RNA - thalamus [nTPM]":"30.0","Tissue RNA - thymus [nTPM]":"21.8","Tissue RNA - thyroid gland [nTPM]":"45.5","Tissue RNA - tongue [nTPM]":"28.1","Tissue RNA - tonsil [nTPM]":"29.8","Tissue RNA - urinary bladder [nTPM]":"153.1","Tissue RNA - vagina [nTPM]":"39.9","Tissue RNA - white matter [nTPM]":"30.6","Cell RNA - A-431 [nTPM]":"66.5","Cell RNA - A549 [nTPM]":"109.6","Cell RNA - AF22 [nTPM]":"152.5","Cell RNA - AN3-CA [nTPM]":"63.3","Cell RNA - ASC diff [nTPM]":"275.1","Cell RNA - ASC TERT1 [nTPM]":"191.4","Cell RNA - BEWO [nTPM]":"86.7","Cell RNA - BJ [nTPM]":"26.3","Cell RNA - BJ hTERT+ [nTPM]":"122.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"44.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"107.3","Cell RNA - CACO-2 [nTPM]":"176.1","Cell RNA - CAPAN-2 [nTPM]":"159.1","Cell RNA - Daudi [nTPM]":"13.1","Cell RNA - EFO-21 [nTPM]":"168.8","Cell RNA - fHDF\/TERT166 [nTPM]":"84.4","Cell RNA - GAMG [nTPM]":"181.6","Cell RNA - HaCaT [nTPM]":"101.4","Cell RNA - HAP1 [nTPM]":"112.4","Cell RNA - HBEC3-KT [nTPM]":"130.7","Cell RNA - HBF TERT88 [nTPM]":"43.0","Cell RNA - HDLM-2 [nTPM]":"8.8","Cell RNA - HEK 293 [nTPM]":"41.7","Cell RNA - HEL [nTPM]":"56.7","Cell RNA - HeLa [nTPM]":"87.3","Cell RNA - Hep G2 [nTPM]":"768.1","Cell RNA - HHSteC [nTPM]":"367.3","Cell RNA - HL-60 [nTPM]":"37.0","Cell RNA - HMC-1 [nTPM]":"54.7","Cell RNA - HSkMC [nTPM]":"169.5","Cell RNA - hTCEpi [nTPM]":"278.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"102.7","Cell RNA - hTERT-HME1 [nTPM]":"74.2","Cell RNA - hTERT-RPE1 [nTPM]":"69.8","Cell RNA - HUVEC TERT2 [nTPM]":"126.1","Cell RNA - JURKAT [nTPM]":"37.2","Cell RNA - K-562 [nTPM]":"58.1","Cell RNA - Karpas-707 [nTPM]":"44.5","Cell RNA - LHCN-M2 [nTPM]":"68.9","Cell RNA - MCF7 [nTPM]":"42.8","Cell RNA - MOLT-4 [nTPM]":"26.3","Cell RNA - NB-4 [nTPM]":"66.2","Cell RNA - NTERA-2 [nTPM]":"284.5","Cell RNA - OE19 [nTPM]":"479.7","Cell RNA - PC-3 [nTPM]":"43.9","Cell RNA - REH [nTPM]":"25.2","Cell RNA - RH-30 [nTPM]":"54.8","Cell RNA - RPMI-8226 [nTPM]":"37.8","Cell RNA - RPTEC TERT1 [nTPM]":"206.3","Cell RNA - RT4 [nTPM]":"524.0","Cell RNA - SCLC-21H [nTPM]":"25.9","Cell RNA - SH-SY5Y [nTPM]":"45.2","Cell RNA - SiHa [nTPM]":"100.5","Cell RNA - SK-BR-3 [nTPM]":"99.7","Cell RNA - SK-MEL-30 [nTPM]":"351.7","Cell RNA - SuSa [nTPM]":"161.2","Cell RNA - T-47d [nTPM]":"37.9","Cell RNA - THP-1 [nTPM]":"111.0","Cell RNA - TIME [nTPM]":"81.1","Cell RNA - U-138 MG [nTPM]":"45.2","Cell RNA - U-2 OS [nTPM]":"44.1","Cell RNA - U-2197 [nTPM]":"65.3","Cell RNA - U-251 MG [nTPM]":"29.6","Cell RNA - U-266\/70 [nTPM]":"20.8","Cell RNA - U-266\/84 [nTPM]":"34.5","Cell RNA - U-698 [nTPM]":"16.9","Cell RNA - U-87 MG [nTPM]":"148.2","Cell RNA - U-937 [nTPM]":"226.7","Cell RNA - WM-115 [nTPM]":"37.0","Blood RNA - basophil [nTPM]":"12.4","Blood RNA - classical monocyte [nTPM]":"70.1","Blood RNA - eosinophil [nTPM]":"11.0","Blood RNA - gdT-cell [nTPM]":"9.1","Blood RNA - intermediate monocyte [nTPM]":"32.3","Blood RNA - MAIT T-cell [nTPM]":"10.6","Blood RNA - memory B-cell [nTPM]":"10.6","Blood RNA - memory CD4 T-cell [nTPM]":"8.2","Blood RNA - memory CD8 T-cell [nTPM]":"10.9","Blood RNA - myeloid DC [nTPM]":"50.9","Blood RNA - naive B-cell [nTPM]":"10.1","Blood RNA - naive CD4 T-cell [nTPM]":"6.7","Blood RNA - naive CD8 T-cell [nTPM]":"7.8","Blood RNA - neutrophil [nTPM]":"13.8","Blood RNA - NK-cell [nTPM]":"17.2","Blood RNA - non-classical monocyte [nTPM]":"15.5","Blood RNA - plasmacytoid DC [nTPM]":"18.8","Blood RNA - T-reg [nTPM]":"15.1","Blood RNA - total PBMC [nTPM]":"29.9","Brain RNA - amygdala [nTPM]":"24.0","Brain RNA - basal ganglia [nTPM]":"23.9","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"30.9","Brain RNA - hippocampal formation [nTPM]":"23.5","Brain RNA - hypothalamus [nTPM]":"26.1","Brain RNA - medulla oblongata [nTPM]":"26.4","Brain RNA - midbrain [nTPM]":"25.7","Brain RNA - pons [nTPM]":"25.9","Brain RNA - spinal cord [nTPM]":"25.5","Brain RNA - thalamus [nTPM]":"30.0","Brain RNA - white matter [nTPM]":"30.6","Single Cell Type RNA - Adipocytes [nTPM]":"13.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.5","Single Cell Type RNA - Astrocytes [nTPM]":"39.2","Single Cell Type RNA - B-cells [nTPM]":"20.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"60.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"52.3","Single Cell Type RNA - Bipolar cells [nTPM]":"19.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"31.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"69.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"320.2","Single Cell Type RNA - dendritic cells [nTPM]":"23.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"106.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"31.1","Single Cell Type RNA - Early spermatids [nTPM]":"13.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"23.4","Single Cell Type RNA - Endothelial cells [nTPM]":"22.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"58.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"86.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"178.8","Single Cell Type RNA - Fibroblasts [nTPM]":"29.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"76.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"108.8","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"257.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"39.7","Single Cell Type RNA - Hepatocytes [nTPM]":"328.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"175.3","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"98.4","Single Cell Type RNA - Ionocytes [nTPM]":"57.0","Single Cell Type RNA - Kupffer cells [nTPM]":"130.2","Single Cell Type RNA - Langerhans cells [nTPM]":"23.8","Single Cell Type RNA - Late spermatids [nTPM]":"11.2","Single Cell Type RNA - Leydig cells [nTPM]":"24.5","Single Cell Type RNA - Macrophages [nTPM]":"71.7","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"47.8","Single Cell Type RNA - Muller glia cells [nTPM]":"25.4","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"66.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.8","Single Cell Type RNA - Paneth cells [nTPM]":"55.5","Single Cell Type RNA - Peritubular cells [nTPM]":"29.3","Single Cell Type RNA - Plasma cells [nTPM]":"13.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"181.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"108.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.6","Single Cell Type RNA - Spermatocytes [nTPM]":"8.0","Single Cell Type RNA - Spermatogonia [nTPM]":"26.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"82.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"95.6","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"127.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"129.3","Single Cell Type RNA - Urothelial cells [nTPM]":"46.7"},{"Gene":"IDH2","Gene synonym":[],"Ensembl":"ENSG00000182054","Gene description":"Isocitrate dehydrogenase (NADP(+)) 2","Uniprot":["P48735"],"Chromosome":"15","Position":"90083045-90102477","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Glyoxylate bypass","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"heart muscle":"492.6","skeletal muscle":"1302.3","tongue":"1611.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"732.5","Distal tubular cells":"1168.0","Extravillous trophoblasts":"586.7","Syncytiotrophoblasts":"573.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"425.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007831"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5200000","Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 47: Cytotrophoblasts - Unknown function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA007831":"AB_1851397"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.15e-5"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.92e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-2"},"Tissue RNA - adipose tissue [nTPM]":"32.8","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"56.5","Tissue RNA - appendix [nTPM]":"60.2","Tissue RNA - basal ganglia [nTPM]":"67.8","Tissue RNA - bone marrow [nTPM]":"161.1","Tissue RNA - breast [nTPM]":"51.1","Tissue RNA - cerebellum [nTPM]":"57.1","Tissue RNA - cerebral cortex [nTPM]":"59.8","Tissue RNA - cervix [nTPM]":"36.6","Tissue RNA - choroid plexus [nTPM]":"76.6","Tissue RNA - colon [nTPM]":"95.9","Tissue RNA - duodenum [nTPM]":"97.2","Tissue RNA - endometrium 1 [nTPM]":"29.0","Tissue RNA - epididymis [nTPM]":"12.5","Tissue RNA - esophagus [nTPM]":"140.6","Tissue RNA - fallopian tube [nTPM]":"32.7","Tissue RNA - gallbladder [nTPM]":"31.7","Tissue RNA - heart muscle [nTPM]":"492.6","Tissue RNA - hippocampal formation [nTPM]":"47.2","Tissue RNA - hypothalamus [nTPM]":"55.0","Tissue RNA - kidney [nTPM]":"208.3","Tissue RNA - liver [nTPM]":"274.7","Tissue RNA - lung [nTPM]":"32.0","Tissue RNA - lymph node [nTPM]":"77.1","Tissue RNA - medulla oblongata [nTPM]":"61.0","Tissue RNA - midbrain [nTPM]":"61.3","Tissue RNA - ovary [nTPM]":"13.6","Tissue RNA - pancreas [nTPM]":"128.7","Tissue RNA - parathyroid gland [nTPM]":"104.0","Tissue RNA - pituitary gland [nTPM]":"15.5","Tissue RNA - placenta [nTPM]":"87.3","Tissue RNA - pons [nTPM]":"54.4","Tissue RNA - prostate [nTPM]":"76.2","Tissue RNA - rectum [nTPM]":"84.1","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"163.1","Tissue RNA - seminal vesicle [nTPM]":"90.4","Tissue RNA - skeletal muscle [nTPM]":"1302.3","Tissue RNA - skin 1 [nTPM]":"61.8","Tissue RNA - small intestine [nTPM]":"84.3","Tissue RNA - smooth muscle [nTPM]":"79.8","Tissue RNA - spinal cord [nTPM]":"52.9","Tissue RNA - spleen [nTPM]":"36.8","Tissue RNA - stomach 1 [nTPM]":"175.7","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"71.6","Tissue RNA - thymus [nTPM]":"148.7","Tissue RNA - thyroid gland [nTPM]":"16.0","Tissue RNA - tongue [nTPM]":"1611.3","Tissue RNA - tonsil [nTPM]":"66.0","Tissue RNA - urinary bladder [nTPM]":"53.3","Tissue RNA - vagina [nTPM]":"49.4","Tissue RNA - white matter [nTPM]":"57.6","Cell RNA - A-431 [nTPM]":"61.3","Cell RNA - A549 [nTPM]":"33.5","Cell RNA - AF22 [nTPM]":"169.9","Cell RNA - AN3-CA [nTPM]":"169.8","Cell RNA - ASC diff [nTPM]":"23.3","Cell RNA - ASC TERT1 [nTPM]":"28.3","Cell RNA - BEWO [nTPM]":"144.5","Cell RNA - BJ [nTPM]":"74.5","Cell RNA - BJ hTERT+ [nTPM]":"110.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.6","Cell RNA - CACO-2 [nTPM]":"16.1","Cell RNA - CAPAN-2 [nTPM]":"51.1","Cell RNA - Daudi [nTPM]":"72.7","Cell RNA - EFO-21 [nTPM]":"21.0","Cell RNA - fHDF\/TERT166 [nTPM]":"61.2","Cell RNA - GAMG [nTPM]":"65.1","Cell RNA - HaCaT [nTPM]":"20.8","Cell RNA - HAP1 [nTPM]":"25.1","Cell RNA - HBEC3-KT [nTPM]":"22.4","Cell RNA - HBF TERT88 [nTPM]":"32.0","Cell RNA - HDLM-2 [nTPM]":"143.8","Cell RNA - HEK 293 [nTPM]":"16.9","Cell RNA - HEL [nTPM]":"122.9","Cell RNA - HeLa [nTPM]":"12.7","Cell RNA - Hep G2 [nTPM]":"119.7","Cell RNA - HHSteC [nTPM]":"28.1","Cell RNA - HL-60 [nTPM]":"85.1","Cell RNA - HMC-1 [nTPM]":"118.2","Cell RNA - HSkMC [nTPM]":"59.7","Cell RNA - hTCEpi [nTPM]":"12.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"16.3","Cell RNA - hTERT-HME1 [nTPM]":"13.0","Cell RNA - hTERT-RPE1 [nTPM]":"82.1","Cell RNA - HUVEC TERT2 [nTPM]":"141.0","Cell RNA - JURKAT [nTPM]":"246.4","Cell RNA - K-562 [nTPM]":"18.9","Cell RNA - Karpas-707 [nTPM]":"59.3","Cell RNA - LHCN-M2 [nTPM]":"53.0","Cell RNA - MCF7 [nTPM]":"175.3","Cell RNA - MOLT-4 [nTPM]":"425.0","Cell RNA - NB-4 [nTPM]":"131.2","Cell RNA - NTERA-2 [nTPM]":"51.8","Cell RNA - OE19 [nTPM]":"81.9","Cell RNA - PC-3 [nTPM]":"14.3","Cell RNA - REH [nTPM]":"352.0","Cell RNA - RH-30 [nTPM]":"122.4","Cell RNA - RPMI-8226 [nTPM]":"213.7","Cell RNA - RPTEC TERT1 [nTPM]":"105.6","Cell RNA - RT4 [nTPM]":"71.3","Cell RNA - SCLC-21H [nTPM]":"244.5","Cell RNA - SH-SY5Y [nTPM]":"125.3","Cell RNA - SiHa [nTPM]":"92.1","Cell RNA - SK-BR-3 [nTPM]":"359.8","Cell RNA - SK-MEL-30 [nTPM]":"29.9","Cell RNA - SuSa [nTPM]":"94.2","Cell RNA - T-47d [nTPM]":"290.9","Cell RNA - THP-1 [nTPM]":"256.9","Cell RNA - TIME [nTPM]":"34.0","Cell RNA - U-138 MG [nTPM]":"120.4","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"16.1","Cell RNA - U-251 MG [nTPM]":"34.9","Cell RNA - U-266\/70 [nTPM]":"101.5","Cell RNA - U-266\/84 [nTPM]":"20.5","Cell RNA - U-698 [nTPM]":"9.0","Cell RNA - U-87 MG [nTPM]":"38.4","Cell RNA - U-937 [nTPM]":"175.0","Cell RNA - WM-115 [nTPM]":"71.2","Blood RNA - basophil [nTPM]":"45.0","Blood RNA - classical monocyte [nTPM]":"112.8","Blood RNA - eosinophil [nTPM]":"75.6","Blood RNA - gdT-cell [nTPM]":"105.9","Blood RNA - intermediate monocyte [nTPM]":"199.1","Blood RNA - MAIT T-cell [nTPM]":"53.2","Blood RNA - memory B-cell [nTPM]":"70.1","Blood RNA - memory CD4 T-cell [nTPM]":"77.0","Blood RNA - memory CD8 T-cell [nTPM]":"120.1","Blood RNA - myeloid DC [nTPM]":"136.9","Blood RNA - naive B-cell [nTPM]":"47.7","Blood RNA - naive CD4 T-cell [nTPM]":"42.9","Blood RNA - naive CD8 T-cell [nTPM]":"71.8","Blood RNA - neutrophil [nTPM]":"22.9","Blood RNA - NK-cell [nTPM]":"99.9","Blood RNA - non-classical monocyte [nTPM]":"252.1","Blood RNA - plasmacytoid DC [nTPM]":"79.4","Blood RNA - T-reg [nTPM]":"72.4","Blood RNA - total PBMC [nTPM]":"163.4","Brain RNA - amygdala [nTPM]":"56.5","Brain RNA - basal ganglia [nTPM]":"67.8","Brain RNA - cerebellum [nTPM]":"57.1","Brain RNA - cerebral cortex [nTPM]":"59.8","Brain RNA - hippocampal formation [nTPM]":"47.2","Brain RNA - hypothalamus [nTPM]":"55.0","Brain RNA - medulla oblongata [nTPM]":"61.0","Brain RNA - midbrain [nTPM]":"61.3","Brain RNA - pons [nTPM]":"54.4","Brain RNA - spinal cord [nTPM]":"52.9","Brain RNA - thalamus [nTPM]":"71.6","Brain RNA - white matter [nTPM]":"57.6","Single Cell Type RNA - Adipocytes [nTPM]":"16.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.0","Single Cell Type RNA - Astrocytes [nTPM]":"40.1","Single Cell Type RNA - B-cells [nTPM]":"64.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"98.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"91.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"6.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"90.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"48.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"445.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"114.4","Single Cell Type RNA - Club cells [nTPM]":"95.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"75.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"732.5","Single Cell Type RNA - dendritic cells [nTPM]":"84.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"70.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1168.0","Single Cell Type RNA - Ductal cells [nTPM]":"252.8","Single Cell Type RNA - Early spermatids [nTPM]":"5.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"96.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.7","Single Cell Type RNA - Endothelial cells [nTPM]":"41.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"61.7","Single Cell Type RNA - Erythroid cells [nTPM]":"193.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"288.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"586.7","Single Cell Type RNA - Fibroblasts [nTPM]":"44.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"88.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"50.9","Single Cell Type RNA - granulocytes [nTPM]":"31.6","Single Cell Type RNA - Granulosa cells [nTPM]":"29.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"38.2","Single Cell Type RNA - Hepatocytes [nTPM]":"283.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"263.7","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"158.3","Single Cell Type RNA - Ionocytes [nTPM]":"229.9","Single Cell Type RNA - Kupffer cells [nTPM]":"77.7","Single Cell Type RNA - Langerhans cells [nTPM]":"101.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"79.0","Single Cell Type RNA - Melanocytes [nTPM]":"58.7","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"85.3","Single Cell Type RNA - Muller glia cells [nTPM]":"20.9","Single Cell Type RNA - NK-cells [nTPM]":"119.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"116.6","Single Cell Type RNA - Paneth cells [nTPM]":"105.0","Single Cell Type RNA - Peritubular cells [nTPM]":"35.3","Single Cell Type RNA - Plasma cells [nTPM]":"185.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"170.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"69.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"205.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"167.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"73.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"15.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"113.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"573.0","Single Cell Type RNA - T-cells [nTPM]":"88.1","Single Cell Type RNA - Theca cells [nTPM]":"14.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"305.1","Single Cell Type RNA - Urothelial cells [nTPM]":"140.1"},{"Gene":"IGF1","Gene synonym":["IGF","IGF-I","IGF1A","IGFI"],"Ensembl":"ENSG00000017427","Gene description":"Insulin like growth factor 1","Uniprot":["P05019"],"Chromosome":"12","Position":"102395874-102481744","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor"],"Disease involvement":["Deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"86.7","cervix":"89.0"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Endometrial stromal cells":"1279.3","Leydig cells":"1103.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"2.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"24","RNA blood lineage specific nTPM":{"B-cells":"2.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"37.9","HDLM-2":"49.6","K-562":"22.4","Karpas-707":"11.3","U-266\/70":"13.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA048946"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":103000000,"Blood concentration - Conc. blood MS [pg\/L]":"330000000","Blood expression cluster":"Cluster 24: B-cells - Unknown function","Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048946":"AB_2680566"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.04e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Tissue RNA - adipose tissue [nTPM]":"86.7","Tissue RNA - adrenal gland [nTPM]":"5.1","Tissue RNA - amygdala [nTPM]":"1.2","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"38.7","Tissue RNA - cerebellum [nTPM]":"0.3","Tissue RNA - cerebral cortex [nTPM]":"2.3","Tissue RNA - cervix [nTPM]":"89.0","Tissue RNA - choroid plexus [nTPM]":"1.3","Tissue RNA - colon [nTPM]":"6.9","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"46.9","Tissue RNA - epididymis [nTPM]":"10.6","Tissue RNA - esophagus [nTPM]":"6.6","Tissue RNA - fallopian tube [nTPM]":"13.0","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"15.1","Tissue RNA - hippocampal formation [nTPM]":"2.2","Tissue RNA - hypothalamus [nTPM]":"1.0","Tissue RNA - kidney [nTPM]":"3.1","Tissue RNA - liver [nTPM]":"83.5","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"6.5","Tissue RNA - medulla oblongata [nTPM]":"2.5","Tissue RNA - midbrain [nTPM]":"1.1","Tissue RNA - ovary [nTPM]":"9.0","Tissue RNA - pancreas [nTPM]":"3.9","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"1.2","Tissue RNA - placenta [nTPM]":"24.2","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"38.5","Tissue RNA - rectum [nTPM]":"6.7","Tissue RNA - retina [nTPM]":"5.4","Tissue RNA - salivary gland [nTPM]":"7.6","Tissue RNA - seminal vesicle [nTPM]":"33.4","Tissue RNA - skeletal muscle [nTPM]":"8.5","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"74.3","Tissue RNA - spinal cord [nTPM]":"1.2","Tissue RNA - spleen [nTPM]":"9.8","Tissue RNA - stomach 1 [nTPM]":"7.7","Tissue RNA - testis [nTPM]":"7.6","Tissue RNA - thalamus [nTPM]":"2.0","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"25.4","Tissue RNA - tongue [nTPM]":"5.9","Tissue RNA - tonsil [nTPM]":"3.7","Tissue RNA - urinary bladder [nTPM]":"21.3","Tissue RNA - vagina [nTPM]":"22.7","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.3","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"37.9","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.3","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.8","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"49.6","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.5","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"22.4","Cell RNA - Karpas-707 [nTPM]":"11.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"1.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"1.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"13.4","Cell RNA - U-266\/84 [nTPM]":"1.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"1.2","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"0.3","Brain RNA - cerebral cortex [nTPM]":"2.3","Brain RNA - hippocampal formation [nTPM]":"2.2","Brain RNA - hypothalamus [nTPM]":"1.0","Brain RNA - medulla oblongata [nTPM]":"2.5","Brain RNA - midbrain [nTPM]":"1.1","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"1.2","Brain RNA - thalamus [nTPM]":"2.0","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"11.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"8.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"168.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"17.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"35.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1279.3","Single Cell Type RNA - Endothelial cells [nTPM]":"38.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"5.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"259.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"34.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"243.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"122.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"123.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"25.8","Single Cell Type RNA - Langerhans cells [nTPM]":"12.5","Single Cell Type RNA - Late spermatids [nTPM]":"58.0","Single Cell Type RNA - Leydig cells [nTPM]":"1103.2","Single Cell Type RNA - Macrophages [nTPM]":"42.0","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"3.6","Single Cell Type RNA - Muller glia cells [nTPM]":"4.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"193.4","Single Cell Type RNA - Plasma cells [nTPM]":"66.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"139.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.6","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"9.1","Single Cell Type RNA - Theca cells [nTPM]":"69.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"IGF1R","Gene synonym":["CD221","IGFIR","IGFR","JTK13","MGC18216"],"Ensembl":"ENSG00000140443","Gene description":"Insulin like growth factor 1 receptor","Uniprot":["P08069"],"Chromosome":"15","Position":"98648539-98964530","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"239.4","Inhibitory neurons":"194.6","Microglial cells":"245.4","Oligodendrocyte precursor cells":"237.7","Oligodendrocytes":"261.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"4.3"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"granulocytes":"4.3","T-cells":"1.4"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010268","HPA045563"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"46000","Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 42: Ciliated cells - Cilium & Cell projection","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010268":"AB_671792","HPA045563":"AB_2679368"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.81e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.56e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.75e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"11.3","Tissue RNA - amygdala [nTPM]":"10.1","Tissue RNA - appendix [nTPM]":"3.6","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"11.0","Tissue RNA - breast [nTPM]":"12.2","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"12.0","Tissue RNA - cervix [nTPM]":"10.1","Tissue RNA - choroid plexus [nTPM]":"35.5","Tissue RNA - colon [nTPM]":"12.5","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"11.1","Tissue RNA - esophagus [nTPM]":"7.5","Tissue RNA - fallopian tube [nTPM]":"13.0","Tissue RNA - gallbladder [nTPM]":"4.5","Tissue RNA - heart muscle [nTPM]":"9.6","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"8.2","Tissue RNA - kidney [nTPM]":"11.6","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"9.5","Tissue RNA - lymph node [nTPM]":"2.7","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"13.4","Tissue RNA - ovary [nTPM]":"15.8","Tissue RNA - pancreas [nTPM]":"15.4","Tissue RNA - parathyroid gland [nTPM]":"2.1","Tissue RNA - pituitary gland [nTPM]":"8.8","Tissue RNA - placenta [nTPM]":"12.1","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"14.7","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"16.0","Tissue RNA - salivary gland [nTPM]":"10.0","Tissue RNA - seminal vesicle [nTPM]":"9.6","Tissue RNA - skeletal muscle [nTPM]":"7.0","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"6.5","Tissue RNA - smooth muscle [nTPM]":"6.1","Tissue RNA - spinal cord [nTPM]":"10.3","Tissue RNA - spleen [nTPM]":"5.8","Tissue RNA - stomach 1 [nTPM]":"9.6","Tissue RNA - testis [nTPM]":"8.4","Tissue RNA - thalamus [nTPM]":"13.2","Tissue RNA - thymus [nTPM]":"6.1","Tissue RNA - thyroid gland [nTPM]":"12.9","Tissue RNA - tongue [nTPM]":"11.6","Tissue RNA - tonsil [nTPM]":"3.4","Tissue RNA - urinary bladder [nTPM]":"9.9","Tissue RNA - vagina [nTPM]":"10.0","Tissue RNA - white matter [nTPM]":"11.1","Cell RNA - A-431 [nTPM]":"6.1","Cell RNA - A549 [nTPM]":"34.0","Cell RNA - AF22 [nTPM]":"22.6","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"11.9","Cell RNA - ASC TERT1 [nTPM]":"8.3","Cell RNA - BEWO [nTPM]":"16.3","Cell RNA - BJ [nTPM]":"8.0","Cell RNA - BJ hTERT+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.2","Cell RNA - CACO-2 [nTPM]":"15.6","Cell RNA - CAPAN-2 [nTPM]":"17.5","Cell RNA - Daudi [nTPM]":"1.6","Cell RNA - EFO-21 [nTPM]":"22.1","Cell RNA - fHDF\/TERT166 [nTPM]":"13.8","Cell RNA - GAMG [nTPM]":"14.7","Cell RNA - HaCaT [nTPM]":"31.6","Cell RNA - HAP1 [nTPM]":"10.9","Cell RNA - HBEC3-KT [nTPM]":"25.0","Cell RNA - HBF TERT88 [nTPM]":"1.9","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"11.1","Cell RNA - HEL [nTPM]":"27.5","Cell RNA - HeLa [nTPM]":"32.3","Cell RNA - Hep G2 [nTPM]":"31.2","Cell RNA - HHSteC [nTPM]":"10.4","Cell RNA - HL-60 [nTPM]":"11.1","Cell RNA - HMC-1 [nTPM]":"2.5","Cell RNA - HSkMC [nTPM]":"12.1","Cell RNA - hTCEpi [nTPM]":"14.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.5","Cell RNA - hTERT-HME1 [nTPM]":"18.6","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"8.4","Cell RNA - JURKAT [nTPM]":"2.8","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"5.4","Cell RNA - LHCN-M2 [nTPM]":"9.9","Cell RNA - MCF7 [nTPM]":"48.1","Cell RNA - MOLT-4 [nTPM]":"5.4","Cell RNA - NB-4 [nTPM]":"9.8","Cell RNA - NTERA-2 [nTPM]":"23.0","Cell RNA - OE19 [nTPM]":"11.8","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"7.7","Cell RNA - RH-30 [nTPM]":"19.3","Cell RNA - RPMI-8226 [nTPM]":"6.7","Cell RNA - RPTEC TERT1 [nTPM]":"7.4","Cell RNA - RT4 [nTPM]":"37.8","Cell RNA - SCLC-21H [nTPM]":"8.1","Cell RNA - SH-SY5Y [nTPM]":"35.9","Cell RNA - SiHa [nTPM]":"56.0","Cell RNA - SK-BR-3 [nTPM]":"3.3","Cell RNA - SK-MEL-30 [nTPM]":"30.1","Cell RNA - SuSa [nTPM]":"50.2","Cell RNA - T-47d [nTPM]":"16.7","Cell RNA - THP-1 [nTPM]":"3.8","Cell RNA - TIME [nTPM]":"24.5","Cell RNA - U-138 MG [nTPM]":"1.5","Cell RNA - U-2 OS [nTPM]":"26.5","Cell RNA - U-2197 [nTPM]":"6.5","Cell RNA - U-251 MG [nTPM]":"12.0","Cell RNA - U-266\/70 [nTPM]":"1.9","Cell RNA - U-266\/84 [nTPM]":"9.8","Cell RNA - U-698 [nTPM]":"5.9","Cell RNA - U-87 MG [nTPM]":"4.6","Cell RNA - U-937 [nTPM]":"10.0","Cell RNA - WM-115 [nTPM]":"5.9","Blood RNA - basophil [nTPM]":"1.9","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.9","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.3","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.4","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"4.3","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"10.1","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"12.0","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"8.2","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"13.4","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"10.3","Brain RNA - thalamus [nTPM]":"13.2","Brain RNA - white matter [nTPM]":"11.1","Single Cell Type RNA - Adipocytes [nTPM]":"30.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.4","Single Cell Type RNA - Astrocytes [nTPM]":"157.7","Single Cell Type RNA - B-cells [nTPM]":"3.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"35.3","Single Cell Type RNA - Bipolar cells [nTPM]":"51.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"30.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.7","Single Cell Type RNA - dendritic cells [nTPM]":"8.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.6","Single Cell Type RNA - Early spermatids [nTPM]":"27.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"79.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"35.0","Single Cell Type RNA - Erythroid cells [nTPM]":"7.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"239.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.3","Single Cell Type RNA - Fibroblasts [nTPM]":"25.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"91.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"106.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"52.5","Single Cell Type RNA - Hepatocytes [nTPM]":"1.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"6.5","Single Cell Type RNA - Horizontal cells [nTPM]":"75.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"194.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.1","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"6.6","Single Cell Type RNA - Langerhans cells [nTPM]":"8.3","Single Cell Type RNA - Late spermatids [nTPM]":"53.4","Single Cell Type RNA - Leydig cells [nTPM]":"18.0","Single Cell Type RNA - Macrophages [nTPM]":"8.3","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"245.4","Single Cell Type RNA - monocytes [nTPM]":"8.5","Single Cell Type RNA - Muller glia cells [nTPM]":"45.6","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"237.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"261.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.1","Single Cell Type RNA - Paneth cells [nTPM]":"12.9","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"4.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"70.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"55.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"36.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"27.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"17.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"17.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"27.5","Single Cell Type RNA - T-cells [nTPM]":"6.4","Single Cell Type RNA - Theca cells [nTPM]":"20.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"51.5"},{"Gene":"IGF2","Gene synonym":["C11orf43","FLJ44734","IGF-II"],"Ensembl":"ENSG00000167244","Gene description":"Insulin like growth factor 2","Uniprot":["P01344"],"Chromosome":"11","Position":"2129112-2141238","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":["Carbohydrate metabolism","Glucose metabolism","Osteogenesis"],"Molecular function":["Growth factor","Hormone","Mitogen"],"Disease involvement":["Cancer-related genes","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"9","RNA tissue specific nTPM":{"placenta":"2749.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cytotrophoblasts":"1104.3","Extravillous trophoblasts":"3196.3","Leydig cells":"3007.5","Peritubular cells":"643.9","Syncytiotrophoblasts":"1612.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebral cortex":"86.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"CACO-2":"862.0","Hep G2":"600.5","LHCN-M2":"333.7","RH-30":"408.5","SH-SY5Y":"495.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007556","HPA007993"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":609000000,"Blood concentration - Conc. blood MS [pg\/L]":"1200000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 28: Placenta - Pregnancy","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 33: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA007556":"AB_2667860","HPA007993":"AB_1851474"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.92e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Tissue RNA - adipose tissue [nTPM]":"99.7","Tissue RNA - adrenal gland [nTPM]":"58.4","Tissue RNA - amygdala [nTPM]":"5.5","Tissue RNA - appendix [nTPM]":"9.2","Tissue RNA - basal ganglia [nTPM]":"32.6","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"41.8","Tissue RNA - cerebellum [nTPM]":"12.6","Tissue RNA - cerebral cortex [nTPM]":"86.0","Tissue RNA - cervix [nTPM]":"75.5","Tissue RNA - choroid plexus [nTPM]":"236.8","Tissue RNA - colon [nTPM]":"22.3","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"75.2","Tissue RNA - epididymis [nTPM]":"52.7","Tissue RNA - esophagus [nTPM]":"18.8","Tissue RNA - fallopian tube [nTPM]":"128.4","Tissue RNA - gallbladder [nTPM]":"34.8","Tissue RNA - heart muscle [nTPM]":"91.7","Tissue RNA - hippocampal formation [nTPM]":"6.5","Tissue RNA - hypothalamus [nTPM]":"7.1","Tissue RNA - kidney [nTPM]":"31.8","Tissue RNA - liver [nTPM]":"305.9","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"20.2","Tissue RNA - midbrain [nTPM]":"6.6","Tissue RNA - ovary [nTPM]":"117.8","Tissue RNA - pancreas [nTPM]":"37.5","Tissue RNA - parathyroid gland [nTPM]":"5.2","Tissue RNA - pituitary gland [nTPM]":"25.4","Tissue RNA - placenta [nTPM]":"2749.2","Tissue RNA - pons [nTPM]":"10.1","Tissue RNA - prostate [nTPM]":"14.5","Tissue RNA - rectum [nTPM]":"4.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"11.6","Tissue RNA - seminal vesicle [nTPM]":"15.2","Tissue RNA - skeletal muscle [nTPM]":"82.1","Tissue RNA - skin 1 [nTPM]":"8.4","Tissue RNA - small intestine [nTPM]":"10.9","Tissue RNA - smooth muscle [nTPM]":"14.7","Tissue RNA - spinal cord [nTPM]":"13.0","Tissue RNA - spleen [nTPM]":"14.4","Tissue RNA - stomach 1 [nTPM]":"11.9","Tissue RNA - testis [nTPM]":"23.7","Tissue RNA - thalamus [nTPM]":"10.9","Tissue RNA - thymus [nTPM]":"3.4","Tissue RNA - thyroid gland [nTPM]":"12.4","Tissue RNA - tongue [nTPM]":"114.0","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"24.2","Tissue RNA - vagina [nTPM]":"23.6","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.8","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"1.8","Cell RNA - BJ [nTPM]":"112.8","Cell RNA - BJ hTERT+ [nTPM]":"1.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"3.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"862.0","Cell RNA - CAPAN-2 [nTPM]":"0.4","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.9","Cell RNA - HBEC3-KT [nTPM]":"7.0","Cell RNA - HBF TERT88 [nTPM]":"7.9","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"0.2","Cell RNA - Hep G2 [nTPM]":"600.5","Cell RNA - HHSteC [nTPM]":"143.4","Cell RNA - HL-60 [nTPM]":"0.7","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"174.7","Cell RNA - hTCEpi [nTPM]":"0.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.7","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.3","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"333.7","Cell RNA - MCF7 [nTPM]":"2.2","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"1.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"408.5","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.9","Cell RNA - SCLC-21H [nTPM]":"32.7","Cell RNA - SH-SY5Y [nTPM]":"495.6","Cell RNA - SiHa [nTPM]":"0.7","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"83.0","Cell RNA - T-47d [nTPM]":"4.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.2","Cell RNA - U-2 OS [nTPM]":"20.1","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"5.5","Brain RNA - basal ganglia [nTPM]":"32.6","Brain RNA - cerebellum [nTPM]":"12.6","Brain RNA - cerebral cortex [nTPM]":"86.0","Brain RNA - hippocampal formation [nTPM]":"6.5","Brain RNA - hypothalamus [nTPM]":"7.1","Brain RNA - medulla oblongata [nTPM]":"20.2","Brain RNA - midbrain [nTPM]":"6.6","Brain RNA - pons [nTPM]":"10.1","Brain RNA - spinal cord [nTPM]":"13.0","Brain RNA - thalamus [nTPM]":"10.9","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"40.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1104.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"13.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"498.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3196.3","Single Cell Type RNA - Fibroblasts [nTPM]":"334.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"171.4","Single Cell Type RNA - Hepatocytes [nTPM]":"494.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"218.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"11.6","Single Cell Type RNA - Langerhans cells [nTPM]":"5.5","Single Cell Type RNA - Late spermatids [nTPM]":"91.1","Single Cell Type RNA - Leydig cells [nTPM]":"3007.5","Single Cell Type RNA - Macrophages [nTPM]":"3.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"643.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.5","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"33.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.5","Single Cell Type RNA - Spermatocytes [nTPM]":"3.8","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1612.9","Single Cell Type RNA - T-cells [nTPM]":"1.8","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.4"},{"Gene":"JAK2","Gene synonym":["JTK10"],"Ensembl":"ENSG00000096968","Gene description":"Janus kinase 2","Uniprot":["O60674"],"Chromosome":"9","Position":"4984390-5129948","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Adaptive immunity","Immunity","Innate immunity"],"Molecular function":["Chromatin regulator","Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"93.4","Inhibitory neurons":"122.3","Microglial cells":"106.8","Oligodendrocyte precursor cells":"69.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"132.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"132.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"ASC diff":"42.2","HDLM-2":"75.0","HEL":"154.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013089","HPA040820","HPA043870"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Focal adhesion sites"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Plasma membrane","Focal adhesion sites"],"Antibody RRID":{"CAB013089":"AB_2533647","HPA040820":"AB_2677151","HPA043870":"AB_2678708"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.49e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"7.6","Tissue RNA - amygdala [nTPM]":"3.2","Tissue RNA - appendix [nTPM]":"19.2","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"21.7","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"6.3","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"8.5","Tissue RNA - choroid plexus [nTPM]":"1.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"11.3","Tissue RNA - epididymis [nTPM]":"8.6","Tissue RNA - esophagus [nTPM]":"8.8","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"24.5","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"3.1","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"10.9","Tissue RNA - lymph node [nTPM]":"18.2","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"3.8","Tissue RNA - parathyroid gland [nTPM]":"6.5","Tissue RNA - pituitary gland [nTPM]":"2.9","Tissue RNA - placenta [nTPM]":"11.0","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"12.8","Tissue RNA - salivary gland [nTPM]":"4.0","Tissue RNA - seminal vesicle [nTPM]":"6.2","Tissue RNA - skeletal muscle [nTPM]":"9.8","Tissue RNA - skin 1 [nTPM]":"11.2","Tissue RNA - small intestine [nTPM]":"7.7","Tissue RNA - smooth muscle [nTPM]":"9.5","Tissue RNA - spinal cord [nTPM]":"3.5","Tissue RNA - spleen [nTPM]":"17.6","Tissue RNA - stomach 1 [nTPM]":"13.4","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"1.7","Tissue RNA - thymus [nTPM]":"7.5","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"8.9","Tissue RNA - tonsil [nTPM]":"12.7","Tissue RNA - urinary bladder [nTPM]":"11.7","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"3.9","Cell RNA - A-431 [nTPM]":"6.8","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"3.7","Cell RNA - AN3-CA [nTPM]":"6.3","Cell RNA - ASC diff [nTPM]":"42.2","Cell RNA - ASC TERT1 [nTPM]":"12.4","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"9.1","Cell RNA - BJ hTERT+ [nTPM]":"8.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.6","Cell RNA - CACO-2 [nTPM]":"1.2","Cell RNA - CAPAN-2 [nTPM]":"2.0","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"2.1","Cell RNA - fHDF\/TERT166 [nTPM]":"5.4","Cell RNA - GAMG [nTPM]":"5.4","Cell RNA - HaCaT [nTPM]":"2.3","Cell RNA - HAP1 [nTPM]":"4.4","Cell RNA - HBEC3-KT [nTPM]":"5.1","Cell RNA - HBF TERT88 [nTPM]":"4.9","Cell RNA - HDLM-2 [nTPM]":"75.0","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"154.7","Cell RNA - HeLa [nTPM]":"7.6","Cell RNA - Hep G2 [nTPM]":"1.7","Cell RNA - HHSteC [nTPM]":"10.0","Cell RNA - HL-60 [nTPM]":"10.5","Cell RNA - HMC-1 [nTPM]":"7.1","Cell RNA - HSkMC [nTPM]":"9.5","Cell RNA - hTCEpi [nTPM]":"2.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.8","Cell RNA - hTERT-HME1 [nTPM]":"4.5","Cell RNA - hTERT-RPE1 [nTPM]":"7.6","Cell RNA - HUVEC TERT2 [nTPM]":"6.6","Cell RNA - JURKAT [nTPM]":"5.1","Cell RNA - K-562 [nTPM]":"10.9","Cell RNA - Karpas-707 [nTPM]":"17.4","Cell RNA - LHCN-M2 [nTPM]":"11.6","Cell RNA - MCF7 [nTPM]":"2.2","Cell RNA - MOLT-4 [nTPM]":"2.9","Cell RNA - NB-4 [nTPM]":"12.8","Cell RNA - NTERA-2 [nTPM]":"3.3","Cell RNA - OE19 [nTPM]":"3.3","Cell RNA - PC-3 [nTPM]":"4.3","Cell RNA - REH [nTPM]":"5.1","Cell RNA - RH-30 [nTPM]":"8.2","Cell RNA - RPMI-8226 [nTPM]":"2.2","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"3.5","Cell RNA - SCLC-21H [nTPM]":"4.2","Cell RNA - SH-SY5Y [nTPM]":"2.4","Cell RNA - SiHa [nTPM]":"2.6","Cell RNA - SK-BR-3 [nTPM]":"3.5","Cell RNA - SK-MEL-30 [nTPM]":"2.8","Cell RNA - SuSa [nTPM]":"3.6","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"13.1","Cell RNA - U-138 MG [nTPM]":"10.2","Cell RNA - U-2 OS [nTPM]":"3.6","Cell RNA - U-2197 [nTPM]":"10.7","Cell RNA - U-251 MG [nTPM]":"6.4","Cell RNA - U-266\/70 [nTPM]":"3.1","Cell RNA - U-266\/84 [nTPM]":"6.4","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"13.6","Cell RNA - U-937 [nTPM]":"4.7","Cell RNA - WM-115 [nTPM]":"5.3","Blood RNA - basophil [nTPM]":"132.5","Blood RNA - classical monocyte [nTPM]":"20.5","Blood RNA - eosinophil [nTPM]":"38.2","Blood RNA - gdT-cell [nTPM]":"5.6","Blood RNA - intermediate monocyte [nTPM]":"20.1","Blood RNA - MAIT T-cell [nTPM]":"4.5","Blood RNA - memory B-cell [nTPM]":"5.6","Blood RNA - memory CD4 T-cell [nTPM]":"4.1","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"26.5","Blood RNA - naive B-cell [nTPM]":"4.9","Blood RNA - naive CD4 T-cell [nTPM]":"2.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.8","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"9.6","Blood RNA - non-classical monocyte [nTPM]":"16.4","Blood RNA - plasmacytoid DC [nTPM]":"9.7","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"7.7","Brain RNA - amygdala [nTPM]":"3.2","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"6.3","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"3.1","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"3.5","Brain RNA - thalamus [nTPM]":"1.7","Brain RNA - white matter [nTPM]":"3.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.9","Single Cell Type RNA - Astrocytes [nTPM]":"31.6","Single Cell Type RNA - B-cells [nTPM]":"12.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"9.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"30.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"6.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - dendritic cells [nTPM]":"13.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.3","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.2","Single Cell Type RNA - Endothelial cells [nTPM]":"9.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"19.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"93.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.9","Single Cell Type RNA - Fibroblasts [nTPM]":"8.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"14.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.2","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"33.6","Single Cell Type RNA - Langerhans cells [nTPM]":"28.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.1","Single Cell Type RNA - Leydig cells [nTPM]":"23.6","Single Cell Type RNA - Macrophages [nTPM]":"38.9","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"106.8","Single Cell Type RNA - monocytes [nTPM]":"49.5","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"69.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"42.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.0","Single Cell Type RNA - Paneth cells [nTPM]":"20.9","Single Cell Type RNA - Peritubular cells [nTPM]":"33.4","Single Cell Type RNA - Plasma cells [nTPM]":"10.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"3.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"11.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"15.0","Single Cell Type RNA - Spermatogonia [nTPM]":"5.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"10.4","Single Cell Type RNA - Theca cells [nTPM]":"5.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.1","Single Cell Type RNA - Urothelial cells [nTPM]":"4.5"},{"Gene":"JUNB","Gene synonym":[],"Ensembl":"ENSG00000171223","Gene description":"JunB proto-oncogene, AP-1 transcription factor subunit","Uniprot":["P17275"],"Chromosome":"19","Position":"12791486-12793315","Protein class":["Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"679.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"679.4","monocytes":"182.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"629.0","U-266\/70":"256.4","U-266\/84":"411.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004464","HPA019149"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004464":"AB_2130023","HPA019149":"AB_1852053"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"722.8","Tissue RNA - adrenal gland [nTPM]":"259.5","Tissue RNA - amygdala [nTPM]":"22.9","Tissue RNA - appendix [nTPM]":"110.3","Tissue RNA - basal ganglia [nTPM]":"28.0","Tissue RNA - bone marrow [nTPM]":"455.2","Tissue RNA - breast [nTPM]":"248.5","Tissue RNA - cerebellum [nTPM]":"90.1","Tissue RNA - cerebral cortex [nTPM]":"65.2","Tissue RNA - cervix [nTPM]":"283.3","Tissue RNA - choroid plexus [nTPM]":"30.4","Tissue RNA - colon [nTPM]":"287.0","Tissue RNA - duodenum [nTPM]":"52.8","Tissue RNA - endometrium 1 [nTPM]":"130.1","Tissue RNA - epididymis [nTPM]":"2.2","Tissue RNA - esophagus [nTPM]":"449.1","Tissue RNA - fallopian tube [nTPM]":"874.8","Tissue RNA - gallbladder [nTPM]":"92.6","Tissue RNA - heart muscle [nTPM]":"383.5","Tissue RNA - hippocampal formation [nTPM]":"28.3","Tissue RNA - hypothalamus [nTPM]":"68.8","Tissue RNA - kidney [nTPM]":"184.2","Tissue RNA - liver [nTPM]":"279.0","Tissue RNA - lung [nTPM]":"399.2","Tissue RNA - lymph node [nTPM]":"65.0","Tissue RNA - medulla oblongata [nTPM]":"83.5","Tissue RNA - midbrain [nTPM]":"29.8","Tissue RNA - ovary [nTPM]":"649.5","Tissue RNA - pancreas [nTPM]":"150.0","Tissue RNA - parathyroid gland [nTPM]":"20.8","Tissue RNA - pituitary gland [nTPM]":"351.9","Tissue RNA - placenta [nTPM]":"39.4","Tissue RNA - pons [nTPM]":"33.6","Tissue RNA - prostate [nTPM]":"195.0","Tissue RNA - rectum [nTPM]":"22.0","Tissue RNA - retina [nTPM]":"32.0","Tissue RNA - salivary gland [nTPM]":"131.6","Tissue RNA - seminal vesicle [nTPM]":"56.1","Tissue RNA - skeletal muscle [nTPM]":"144.6","Tissue RNA - skin 1 [nTPM]":"605.9","Tissue RNA - small intestine [nTPM]":"145.0","Tissue RNA - smooth muscle [nTPM]":"58.1","Tissue RNA - spinal cord [nTPM]":"51.5","Tissue RNA - spleen [nTPM]":"153.3","Tissue RNA - stomach 1 [nTPM]":"309.8","Tissue RNA - testis [nTPM]":"30.0","Tissue RNA - thalamus [nTPM]":"31.3","Tissue RNA - thymus [nTPM]":"78.8","Tissue RNA - thyroid gland [nTPM]":"198.7","Tissue RNA - tongue [nTPM]":"73.3","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"333.0","Tissue RNA - vagina [nTPM]":"330.6","Tissue RNA - white matter [nTPM]":"34.8","Cell RNA - A-431 [nTPM]":"52.9","Cell RNA - A549 [nTPM]":"10.4","Cell RNA - AF22 [nTPM]":"2.8","Cell RNA - AN3-CA [nTPM]":"6.4","Cell RNA - ASC diff [nTPM]":"11.3","Cell RNA - ASC TERT1 [nTPM]":"27.4","Cell RNA - BEWO [nTPM]":"10.2","Cell RNA - BJ [nTPM]":"22.8","Cell RNA - BJ hTERT+ [nTPM]":"19.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"11.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.0","Cell RNA - CACO-2 [nTPM]":"6.8","Cell RNA - CAPAN-2 [nTPM]":"30.4","Cell RNA - Daudi [nTPM]":"18.2","Cell RNA - EFO-21 [nTPM]":"77.4","Cell RNA - fHDF\/TERT166 [nTPM]":"8.4","Cell RNA - GAMG [nTPM]":"33.5","Cell RNA - HaCaT [nTPM]":"98.5","Cell RNA - HAP1 [nTPM]":"2.5","Cell RNA - HBEC3-KT [nTPM]":"34.3","Cell RNA - HBF TERT88 [nTPM]":"1.2","Cell RNA - HDLM-2 [nTPM]":"629.0","Cell RNA - HEK 293 [nTPM]":"9.9","Cell RNA - HEL [nTPM]":"18.0","Cell RNA - HeLa [nTPM]":"42.2","Cell RNA - Hep G2 [nTPM]":"9.0","Cell RNA - HHSteC [nTPM]":"15.1","Cell RNA - HL-60 [nTPM]":"24.3","Cell RNA - HMC-1 [nTPM]":"80.5","Cell RNA - HSkMC [nTPM]":"34.9","Cell RNA - hTCEpi [nTPM]":"97.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"10.0","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"22.0","Cell RNA - HUVEC TERT2 [nTPM]":"5.3","Cell RNA - JURKAT [nTPM]":"12.9","Cell RNA - K-562 [nTPM]":"48.1","Cell RNA - Karpas-707 [nTPM]":"32.6","Cell RNA - LHCN-M2 [nTPM]":"3.6","Cell RNA - MCF7 [nTPM]":"158.8","Cell RNA - MOLT-4 [nTPM]":"16.8","Cell RNA - NB-4 [nTPM]":"147.5","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"36.1","Cell RNA - PC-3 [nTPM]":"40.0","Cell RNA - REH [nTPM]":"22.4","Cell RNA - RH-30 [nTPM]":"7.7","Cell RNA - RPMI-8226 [nTPM]":"38.8","Cell RNA - RPTEC TERT1 [nTPM]":"7.5","Cell RNA - RT4 [nTPM]":"65.5","Cell RNA - SCLC-21H [nTPM]":"23.7","Cell RNA - SH-SY5Y [nTPM]":"36.0","Cell RNA - SiHa [nTPM]":"98.4","Cell RNA - SK-BR-3 [nTPM]":"59.5","Cell RNA - SK-MEL-30 [nTPM]":"30.5","Cell RNA - SuSa [nTPM]":"1.7","Cell RNA - T-47d [nTPM]":"10.5","Cell RNA - THP-1 [nTPM]":"27.0","Cell RNA - TIME [nTPM]":"17.6","Cell RNA - U-138 MG [nTPM]":"32.2","Cell RNA - U-2 OS [nTPM]":"18.7","Cell RNA - U-2197 [nTPM]":"64.3","Cell RNA - U-251 MG [nTPM]":"28.9","Cell RNA - U-266\/70 [nTPM]":"256.4","Cell RNA - U-266\/84 [nTPM]":"411.4","Cell RNA - U-698 [nTPM]":"17.1","Cell RNA - U-87 MG [nTPM]":"37.7","Cell RNA - U-937 [nTPM]":"62.7","Cell RNA - WM-115 [nTPM]":"8.9","Blood RNA - basophil [nTPM]":"29.1","Blood RNA - classical monocyte [nTPM]":"132.2","Blood RNA - eosinophil [nTPM]":"132.2","Blood RNA - gdT-cell [nTPM]":"33.4","Blood RNA - intermediate monocyte [nTPM]":"182.7","Blood RNA - MAIT T-cell [nTPM]":"33.4","Blood RNA - memory B-cell [nTPM]":"30.6","Blood RNA - memory CD4 T-cell [nTPM]":"36.8","Blood RNA - memory CD8 T-cell [nTPM]":"42.0","Blood RNA - myeloid DC [nTPM]":"87.1","Blood RNA - naive B-cell [nTPM]":"25.4","Blood RNA - naive CD4 T-cell [nTPM]":"25.5","Blood RNA - naive CD8 T-cell [nTPM]":"28.5","Blood RNA - neutrophil [nTPM]":"679.4","Blood RNA - NK-cell [nTPM]":"18.6","Blood RNA - non-classical monocyte [nTPM]":"177.2","Blood RNA - plasmacytoid DC [nTPM]":"7.9","Blood RNA - T-reg [nTPM]":"38.7","Blood RNA - total PBMC [nTPM]":"124.1","Brain RNA - amygdala [nTPM]":"22.9","Brain RNA - basal ganglia [nTPM]":"28.0","Brain RNA - cerebellum [nTPM]":"90.1","Brain RNA - cerebral cortex [nTPM]":"65.2","Brain RNA - hippocampal formation [nTPM]":"28.3","Brain RNA - hypothalamus [nTPM]":"68.8","Brain RNA - medulla oblongata [nTPM]":"83.5","Brain RNA - midbrain [nTPM]":"29.8","Brain RNA - pons [nTPM]":"33.6","Brain RNA - spinal cord [nTPM]":"51.5","Brain RNA - thalamus [nTPM]":"31.3","Brain RNA - white matter [nTPM]":"34.8","Single Cell Type RNA - Adipocytes [nTPM]":"3158.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"115.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"423.2","Single Cell Type RNA - Astrocytes [nTPM]":"130.2","Single Cell Type RNA - B-cells [nTPM]":"1751.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1463.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1778.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2367.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1985.1","Single Cell Type RNA - Bipolar cells [nTPM]":"81.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1296.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1693.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"374.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"474.7","Single Cell Type RNA - Club cells [nTPM]":"707.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"154.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"129.7","Single Cell Type RNA - dendritic cells [nTPM]":"1766.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"819.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"49.0","Single Cell Type RNA - Ductal cells [nTPM]":"833.3","Single Cell Type RNA - Early spermatids [nTPM]":"9.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"468.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1091.4","Single Cell Type RNA - Endothelial cells [nTPM]":"1469.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1502.1","Single Cell Type RNA - Erythroid cells [nTPM]":"244.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"546.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"224.7","Single Cell Type RNA - Fibroblasts [nTPM]":"2182.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1060.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"627.8","Single Cell Type RNA - granulocytes [nTPM]":"510.5","Single Cell Type RNA - Granulosa cells [nTPM]":"310.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"852.4","Single Cell Type RNA - Hepatocytes [nTPM]":"84.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"1178.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1029.3","Single Cell Type RNA - Ionocytes [nTPM]":"740.6","Single Cell Type RNA - Kupffer cells [nTPM]":"674.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2747.6","Single Cell Type RNA - Late spermatids [nTPM]":"27.9","Single Cell Type RNA - Leydig cells [nTPM]":"815.2","Single Cell Type RNA - Macrophages [nTPM]":"1583.3","Single Cell Type RNA - Melanocytes [nTPM]":"894.6","Single Cell Type RNA - Microglial cells [nTPM]":"20.6","Single Cell Type RNA - monocytes [nTPM]":"379.3","Single Cell Type RNA - Muller glia cells [nTPM]":"634.6","Single Cell Type RNA - NK-cells [nTPM]":"115.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1026.7","Single Cell Type RNA - Paneth cells [nTPM]":"875.3","Single Cell Type RNA - Peritubular cells [nTPM]":"263.3","Single Cell Type RNA - Plasma cells [nTPM]":"842.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1036.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"701.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"84.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"337.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"168.8","Single Cell Type RNA - Sertoli cells [nTPM]":"1163.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2566.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2624.1","Single Cell Type RNA - Spermatocytes [nTPM]":"9.4","Single Cell Type RNA - Spermatogonia [nTPM]":"10.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1164.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1804.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"440.3","Single Cell Type RNA - T-cells [nTPM]":"2362.6","Single Cell Type RNA - Theca cells [nTPM]":"417.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"687.7","Single Cell Type RNA - Urothelial cells [nTPM]":"472.6"},{"Gene":"KDM6A","Gene synonym":["UTX"],"Ensembl":"ENSG00000147050","Gene description":"Lysine demethylase 6A","Uniprot":["O15550"],"Chromosome":"X","Position":"44873188-45112779","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Chromatin regulator","Dioxygenase","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Microglial cells":"116.2","Oligodendrocyte precursor cells":"118.1","Oligodendrocytes":"264.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000568","HPA001165","HPA002111"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 71: Testis - DNA repair","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA000568":"AB_1858705","HPA001165":"AB_1080541","HPA002111":"AB_1858704"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.22e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.18e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Tissue RNA - adipose tissue [nTPM]":"9.6","Tissue RNA - adrenal gland [nTPM]":"8.0","Tissue RNA - amygdala [nTPM]":"6.7","Tissue RNA - appendix [nTPM]":"4.5","Tissue RNA - basal ganglia [nTPM]":"7.6","Tissue RNA - bone marrow [nTPM]":"19.4","Tissue RNA - breast [nTPM]":"10.6","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"6.5","Tissue RNA - colon [nTPM]":"9.1","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"14.0","Tissue RNA - epididymis [nTPM]":"5.1","Tissue RNA - esophagus [nTPM]":"11.1","Tissue RNA - fallopian tube [nTPM]":"14.0","Tissue RNA - gallbladder [nTPM]":"3.4","Tissue RNA - heart muscle [nTPM]":"6.6","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"6.9","Tissue RNA - kidney [nTPM]":"6.8","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"10.8","Tissue RNA - lymph node [nTPM]":"8.0","Tissue RNA - medulla oblongata [nTPM]":"7.3","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"17.2","Tissue RNA - pancreas [nTPM]":"10.8","Tissue RNA - parathyroid gland [nTPM]":"6.4","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"3.9","Tissue RNA - pons [nTPM]":"7.3","Tissue RNA - prostate [nTPM]":"7.7","Tissue RNA - rectum [nTPM]":"4.1","Tissue RNA - retina [nTPM]":"3.8","Tissue RNA - salivary gland [nTPM]":"10.5","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"10.4","Tissue RNA - skin 1 [nTPM]":"18.4","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"12.2","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"12.9","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"9.8","Tissue RNA - vagina [nTPM]":"15.2","Tissue RNA - white matter [nTPM]":"9.9","Cell RNA - A-431 [nTPM]":"7.3","Cell RNA - A549 [nTPM]":"5.8","Cell RNA - AF22 [nTPM]":"7.0","Cell RNA - AN3-CA [nTPM]":"9.3","Cell RNA - ASC diff [nTPM]":"5.0","Cell RNA - ASC TERT1 [nTPM]":"6.8","Cell RNA - BEWO [nTPM]":"15.7","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.1","Cell RNA - CACO-2 [nTPM]":"10.4","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"4.6","Cell RNA - EFO-21 [nTPM]":"3.2","Cell RNA - fHDF\/TERT166 [nTPM]":"3.5","Cell RNA - GAMG [nTPM]":"10.1","Cell RNA - HaCaT [nTPM]":"13.9","Cell RNA - HAP1 [nTPM]":"6.5","Cell RNA - HBEC3-KT [nTPM]":"5.4","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"7.6","Cell RNA - HEK 293 [nTPM]":"10.8","Cell RNA - HEL [nTPM]":"2.4","Cell RNA - HeLa [nTPM]":"4.5","Cell RNA - Hep G2 [nTPM]":"5.2","Cell RNA - HHSteC [nTPM]":"3.7","Cell RNA - HL-60 [nTPM]":"2.6","Cell RNA - HMC-1 [nTPM]":"13.2","Cell RNA - HSkMC [nTPM]":"2.6","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.2","Cell RNA - hTERT-HME1 [nTPM]":"6.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"5.3","Cell RNA - K-562 [nTPM]":"6.4","Cell RNA - Karpas-707 [nTPM]":"10.1","Cell RNA - LHCN-M2 [nTPM]":"2.4","Cell RNA - MCF7 [nTPM]":"6.0","Cell RNA - MOLT-4 [nTPM]":"6.9","Cell RNA - NB-4 [nTPM]":"13.6","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"4.2","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"6.4","Cell RNA - RH-30 [nTPM]":"7.1","Cell RNA - RPMI-8226 [nTPM]":"1.4","Cell RNA - RPTEC TERT1 [nTPM]":"3.8","Cell RNA - RT4 [nTPM]":"9.2","Cell RNA - SCLC-21H [nTPM]":"6.2","Cell RNA - SH-SY5Y [nTPM]":"4.4","Cell RNA - SiHa [nTPM]":"18.2","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"10.7","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"8.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"3.0","Cell RNA - U-138 MG [nTPM]":"5.4","Cell RNA - U-2 OS [nTPM]":"5.2","Cell RNA - U-2197 [nTPM]":"5.2","Cell RNA - U-251 MG [nTPM]":"3.6","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"8.8","Cell RNA - U-698 [nTPM]":"5.6","Cell RNA - U-87 MG [nTPM]":"4.0","Cell RNA - U-937 [nTPM]":"3.3","Cell RNA - WM-115 [nTPM]":"3.3","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"1.7","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"3.5","Blood RNA - MAIT T-cell [nTPM]":"2.1","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.8","Blood RNA - myeloid DC [nTPM]":"3.1","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.5","Blood RNA - naive CD8 T-cell [nTPM]":"2.4","Blood RNA - neutrophil [nTPM]":"2.8","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"3.0","Blood RNA - plasmacytoid DC [nTPM]":"1.7","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"2.0","Brain RNA - amygdala [nTPM]":"6.7","Brain RNA - basal ganglia [nTPM]":"7.6","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"6.9","Brain RNA - medulla oblongata [nTPM]":"7.3","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"7.3","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"9.9","Single Cell Type RNA - Adipocytes [nTPM]":"23.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.6","Single Cell Type RNA - Astrocytes [nTPM]":"92.1","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"26.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"7.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - dendritic cells [nTPM]":"26.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"24.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"8.4","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"26.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.5","Single Cell Type RNA - Endothelial cells [nTPM]":"13.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"88.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.7","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"27.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"17.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.1","Single Cell Type RNA - Langerhans cells [nTPM]":"13.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.0","Single Cell Type RNA - Leydig cells [nTPM]":"6.5","Single Cell Type RNA - Macrophages [nTPM]":"19.9","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"116.2","Single Cell Type RNA - monocytes [nTPM]":"12.6","Single Cell Type RNA - Muller glia cells [nTPM]":"6.8","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"118.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"264.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"31.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.0","Single Cell Type RNA - Spermatocytes [nTPM]":"14.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"29.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"26.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"10.9","Single Cell Type RNA - T-cells [nTPM]":"27.4","Single Cell Type RNA - Theca cells [nTPM]":"10.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.1","Single Cell Type RNA - Urothelial cells [nTPM]":"17.1"},{"Gene":"KEAP1","Gene synonym":["INrf2","KIAA0132","KLHL19","MGC10630","MGC1114","MGC20887","MGC4407","MGC9454"],"Ensembl":"ENSG00000079999","Gene description":"Kelch like ECH associated protein 1","Uniprot":["Q14145"],"Chromosome":"19","Position":"10486125-10503558","Protein class":["Cancer-related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"178.2"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005558","CAB025337"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centriolar satellite","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm","Centriolar satellite"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB025337":null,"HPA005558":"AB_1079175"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.28e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.64e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.71e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"31.3","Tissue RNA - adrenal gland [nTPM]":"41.2","Tissue RNA - amygdala [nTPM]":"54.8","Tissue RNA - appendix [nTPM]":"20.5","Tissue RNA - basal ganglia [nTPM]":"61.6","Tissue RNA - bone marrow [nTPM]":"20.4","Tissue RNA - breast [nTPM]":"30.3","Tissue RNA - cerebellum [nTPM]":"61.8","Tissue RNA - cerebral cortex [nTPM]":"60.9","Tissue RNA - cervix [nTPM]":"32.7","Tissue RNA - choroid plexus [nTPM]":"49.7","Tissue RNA - colon [nTPM]":"37.6","Tissue RNA - duodenum [nTPM]":"26.5","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"22.2","Tissue RNA - esophagus [nTPM]":"55.4","Tissue RNA - fallopian tube [nTPM]":"28.9","Tissue RNA - gallbladder [nTPM]":"24.3","Tissue RNA - heart muscle [nTPM]":"60.7","Tissue RNA - hippocampal formation [nTPM]":"53.2","Tissue RNA - hypothalamus [nTPM]":"59.4","Tissue RNA - kidney [nTPM]":"32.5","Tissue RNA - liver [nTPM]":"60.9","Tissue RNA - lung [nTPM]":"25.3","Tissue RNA - lymph node [nTPM]":"23.2","Tissue RNA - medulla oblongata [nTPM]":"61.4","Tissue RNA - midbrain [nTPM]":"60.5","Tissue RNA - ovary [nTPM]":"25.3","Tissue RNA - pancreas [nTPM]":"32.8","Tissue RNA - parathyroid gland [nTPM]":"24.3","Tissue RNA - pituitary gland [nTPM]":"30.0","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"60.3","Tissue RNA - prostate [nTPM]":"36.8","Tissue RNA - rectum [nTPM]":"16.5","Tissue RNA - retina [nTPM]":"16.4","Tissue RNA - salivary gland [nTPM]":"34.7","Tissue RNA - seminal vesicle [nTPM]":"24.9","Tissue RNA - skeletal muscle [nTPM]":"178.2","Tissue RNA - skin 1 [nTPM]":"38.7","Tissue RNA - small intestine [nTPM]":"27.5","Tissue RNA - smooth muscle [nTPM]":"18.7","Tissue RNA - spinal cord [nTPM]":"58.8","Tissue RNA - spleen [nTPM]":"32.2","Tissue RNA - stomach 1 [nTPM]":"33.2","Tissue RNA - testis [nTPM]":"20.5","Tissue RNA - thalamus [nTPM]":"59.6","Tissue RNA - thymus [nTPM]":"23.0","Tissue RNA - thyroid gland [nTPM]":"35.6","Tissue RNA - tongue [nTPM]":"75.7","Tissue RNA - tonsil [nTPM]":"18.5","Tissue RNA - urinary bladder [nTPM]":"41.4","Tissue RNA - vagina [nTPM]":"36.3","Tissue RNA - white matter [nTPM]":"68.4","Cell RNA - A-431 [nTPM]":"58.0","Cell RNA - A549 [nTPM]":"102.8","Cell RNA - AF22 [nTPM]":"27.2","Cell RNA - AN3-CA [nTPM]":"35.1","Cell RNA - ASC diff [nTPM]":"55.8","Cell RNA - ASC TERT1 [nTPM]":"45.4","Cell RNA - BEWO [nTPM]":"30.3","Cell RNA - BJ [nTPM]":"48.1","Cell RNA - BJ hTERT+ [nTPM]":"35.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"46.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.6","Cell RNA - CACO-2 [nTPM]":"73.7","Cell RNA - CAPAN-2 [nTPM]":"54.2","Cell RNA - Daudi [nTPM]":"82.9","Cell RNA - EFO-21 [nTPM]":"122.9","Cell RNA - fHDF\/TERT166 [nTPM]":"53.3","Cell RNA - GAMG [nTPM]":"34.8","Cell RNA - HaCaT [nTPM]":"49.7","Cell RNA - HAP1 [nTPM]":"55.6","Cell RNA - HBEC3-KT [nTPM]":"36.9","Cell RNA - HBF TERT88 [nTPM]":"23.7","Cell RNA - HDLM-2 [nTPM]":"78.3","Cell RNA - HEK 293 [nTPM]":"61.7","Cell RNA - HEL [nTPM]":"126.3","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"87.9","Cell RNA - HHSteC [nTPM]":"54.5","Cell RNA - HL-60 [nTPM]":"65.4","Cell RNA - HMC-1 [nTPM]":"63.9","Cell RNA - HSkMC [nTPM]":"50.0","Cell RNA - hTCEpi [nTPM]":"51.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.5","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"39.1","Cell RNA - HUVEC TERT2 [nTPM]":"46.3","Cell RNA - JURKAT [nTPM]":"23.7","Cell RNA - K-562 [nTPM]":"79.1","Cell RNA - Karpas-707 [nTPM]":"135.4","Cell RNA - LHCN-M2 [nTPM]":"41.6","Cell RNA - MCF7 [nTPM]":"79.9","Cell RNA - MOLT-4 [nTPM]":"46.1","Cell RNA - NB-4 [nTPM]":"177.8","Cell RNA - NTERA-2 [nTPM]":"80.8","Cell RNA - OE19 [nTPM]":"54.2","Cell RNA - PC-3 [nTPM]":"88.6","Cell RNA - REH [nTPM]":"84.6","Cell RNA - RH-30 [nTPM]":"34.8","Cell RNA - RPMI-8226 [nTPM]":"95.1","Cell RNA - RPTEC TERT1 [nTPM]":"30.4","Cell RNA - RT4 [nTPM]":"67.4","Cell RNA - SCLC-21H [nTPM]":"75.3","Cell RNA - SH-SY5Y [nTPM]":"40.4","Cell RNA - SiHa [nTPM]":"66.8","Cell RNA - SK-BR-3 [nTPM]":"42.4","Cell RNA - SK-MEL-30 [nTPM]":"42.1","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"37.8","Cell RNA - THP-1 [nTPM]":"82.3","Cell RNA - TIME [nTPM]":"56.5","Cell RNA - U-138 MG [nTPM]":"72.9","Cell RNA - U-2 OS [nTPM]":"41.0","Cell RNA - U-2197 [nTPM]":"86.0","Cell RNA - U-251 MG [nTPM]":"57.0","Cell RNA - U-266\/70 [nTPM]":"86.8","Cell RNA - U-266\/84 [nTPM]":"113.0","Cell RNA - U-698 [nTPM]":"81.1","Cell RNA - U-87 MG [nTPM]":"58.0","Cell RNA - U-937 [nTPM]":"78.5","Cell RNA - WM-115 [nTPM]":"56.0","Blood RNA - basophil [nTPM]":"36.4","Blood RNA - classical monocyte [nTPM]":"37.9","Blood RNA - eosinophil [nTPM]":"41.4","Blood RNA - gdT-cell [nTPM]":"55.3","Blood RNA - intermediate monocyte [nTPM]":"33.8","Blood RNA - MAIT T-cell [nTPM]":"53.1","Blood RNA - memory B-cell [nTPM]":"26.3","Blood RNA - memory CD4 T-cell [nTPM]":"38.5","Blood RNA - memory CD8 T-cell [nTPM]":"52.0","Blood RNA - myeloid DC [nTPM]":"45.4","Blood RNA - naive B-cell [nTPM]":"11.7","Blood RNA - naive CD4 T-cell [nTPM]":"23.6","Blood RNA - naive CD8 T-cell [nTPM]":"33.7","Blood RNA - neutrophil [nTPM]":"20.9","Blood RNA - NK-cell [nTPM]":"42.5","Blood RNA - non-classical monocyte [nTPM]":"34.6","Blood RNA - plasmacytoid DC [nTPM]":"31.4","Blood RNA - T-reg [nTPM]":"50.2","Blood RNA - total PBMC [nTPM]":"41.8","Brain RNA - amygdala [nTPM]":"54.8","Brain RNA - basal ganglia [nTPM]":"61.6","Brain RNA - cerebellum [nTPM]":"61.8","Brain RNA - cerebral cortex [nTPM]":"60.9","Brain RNA - hippocampal formation [nTPM]":"53.2","Brain RNA - hypothalamus [nTPM]":"59.4","Brain RNA - medulla oblongata [nTPM]":"61.4","Brain RNA - midbrain [nTPM]":"60.5","Brain RNA - pons [nTPM]":"60.3","Brain RNA - spinal cord [nTPM]":"58.8","Brain RNA - thalamus [nTPM]":"59.6","Brain RNA - white matter [nTPM]":"68.4","Single Cell Type RNA - Adipocytes [nTPM]":"18.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.8","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"13.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"21.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"24.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"40.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"27.9","Single Cell Type RNA - Bipolar cells [nTPM]":"21.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"24.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"25.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.3","Single Cell Type RNA - dendritic cells [nTPM]":"11.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"33.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"32.8","Single Cell Type RNA - Early spermatids [nTPM]":"27.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.1","Single Cell Type RNA - Endothelial cells [nTPM]":"27.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.9","Single Cell Type RNA - Erythroid cells [nTPM]":"45.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"36.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.2","Single Cell Type RNA - Fibroblasts [nTPM]":"23.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"18.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.3","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"22.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.3","Single Cell Type RNA - Hepatocytes [nTPM]":"34.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"29.0","Single Cell Type RNA - Horizontal cells [nTPM]":"26.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.4","Single Cell Type RNA - Ionocytes [nTPM]":"40.7","Single Cell Type RNA - Kupffer cells [nTPM]":"15.1","Single Cell Type RNA - Langerhans cells [nTPM]":"13.4","Single Cell Type RNA - Late spermatids [nTPM]":"43.9","Single Cell Type RNA - Leydig cells [nTPM]":"29.2","Single Cell Type RNA - Macrophages [nTPM]":"16.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"41.8","Single Cell Type RNA - Muller glia cells [nTPM]":"43.0","Single Cell Type RNA - NK-cells [nTPM]":"7.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.8","Single Cell Type RNA - Paneth cells [nTPM]":"27.1","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"26.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.9","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.4","Single Cell Type RNA - Spermatocytes [nTPM]":"21.2","Single Cell Type RNA - Spermatogonia [nTPM]":"16.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"34.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.8","Single Cell Type RNA - T-cells [nTPM]":"20.1","Single Cell Type RNA - Theca cells [nTPM]":"29.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"31.5","Single Cell Type RNA - Urothelial cells [nTPM]":"24.8"},{"Gene":"KIF14","Gene synonym":["KIAA0042"],"Ensembl":"ENSG00000118193","Gene description":"Kinesin family member 14","Uniprot":["Q15058"],"Chromosome":"1","Position":"200551497-200620751","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Motor protein"],"Disease involvement":["Ciliopathy","Disease variant","Meckel syndrome","Primary microcephaly"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"6.5","lymphoid tissue":"10.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"27.1","Granulosa cells":"13.2","Spermatocytes":"22.8","Spermatogonia":"16.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA038061","HPA058220"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Midbody ring","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Cytosol"],"Subcellular additional location":["Midbody ring"],"Antibody RRID":{"HPA038061":"AB_10669515","HPA058220":"AB_2683642"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.64e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.47e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.54e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"0.00e+0"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.28e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.44e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"2.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.3","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.9","Tissue RNA - duodenum [nTPM]":"1.2","Tissue RNA - endometrium 1 [nTPM]":"0.3","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"1.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.2","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.3","Tissue RNA - lung [nTPM]":"0.2","Tissue RNA - lymph node [nTPM]":"3.2","Tissue RNA - medulla oblongata [nTPM]":"0.1","Tissue RNA - midbrain [nTPM]":"0.2","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.9","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"1.2","Tissue RNA - retina [nTPM]":"0.1","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"1.0","Tissue RNA - small intestine [nTPM]":"1.1","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.6","Tissue RNA - stomach 1 [nTPM]":"0.6","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"0.4","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"29.7","Cell RNA - A549 [nTPM]":"17.3","Cell RNA - AF22 [nTPM]":"26.8","Cell RNA - AN3-CA [nTPM]":"15.0","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"3.0","Cell RNA - BEWO [nTPM]":"14.8","Cell RNA - BJ [nTPM]":"20.0","Cell RNA - BJ hTERT+ [nTPM]":"11.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.8","Cell RNA - CACO-2 [nTPM]":"10.5","Cell RNA - CAPAN-2 [nTPM]":"15.1","Cell RNA - Daudi [nTPM]":"18.0","Cell RNA - EFO-21 [nTPM]":"7.0","Cell RNA - fHDF\/TERT166 [nTPM]":"9.6","Cell RNA - GAMG [nTPM]":"11.6","Cell RNA - HaCaT [nTPM]":"23.0","Cell RNA - HAP1 [nTPM]":"21.6","Cell RNA - HBEC3-KT [nTPM]":"13.3","Cell RNA - HBF TERT88 [nTPM]":"26.7","Cell RNA - HDLM-2 [nTPM]":"22.1","Cell RNA - HEK 293 [nTPM]":"11.3","Cell RNA - HEL [nTPM]":"28.8","Cell RNA - HeLa [nTPM]":"24.8","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"45.5","Cell RNA - HMC-1 [nTPM]":"15.7","Cell RNA - HSkMC [nTPM]":"0.6","Cell RNA - hTCEpi [nTPM]":"0.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.9","Cell RNA - hTERT-HME1 [nTPM]":"17.8","Cell RNA - hTERT-RPE1 [nTPM]":"4.0","Cell RNA - HUVEC TERT2 [nTPM]":"13.5","Cell RNA - JURKAT [nTPM]":"26.3","Cell RNA - K-562 [nTPM]":"44.0","Cell RNA - Karpas-707 [nTPM]":"22.6","Cell RNA - LHCN-M2 [nTPM]":"23.5","Cell RNA - MCF7 [nTPM]":"12.1","Cell RNA - MOLT-4 [nTPM]":"26.9","Cell RNA - NB-4 [nTPM]":"14.2","Cell RNA - NTERA-2 [nTPM]":"22.6","Cell RNA - OE19 [nTPM]":"8.7","Cell RNA - PC-3 [nTPM]":"15.0","Cell RNA - REH [nTPM]":"24.3","Cell RNA - RH-30 [nTPM]":"35.4","Cell RNA - RPMI-8226 [nTPM]":"22.8","Cell RNA - RPTEC TERT1 [nTPM]":"6.3","Cell RNA - RT4 [nTPM]":"8.3","Cell RNA - SCLC-21H [nTPM]":"12.7","Cell RNA - SH-SY5Y [nTPM]":"14.0","Cell RNA - SiHa [nTPM]":"28.3","Cell RNA - SK-BR-3 [nTPM]":"9.5","Cell RNA - SK-MEL-30 [nTPM]":"11.0","Cell RNA - SuSa [nTPM]":"19.8","Cell RNA - T-47d [nTPM]":"12.9","Cell RNA - THP-1 [nTPM]":"11.6","Cell RNA - TIME [nTPM]":"11.1","Cell RNA - U-138 MG [nTPM]":"14.7","Cell RNA - U-2 OS [nTPM]":"17.3","Cell RNA - U-2197 [nTPM]":"16.2","Cell RNA - U-251 MG [nTPM]":"35.3","Cell RNA - U-266\/70 [nTPM]":"8.2","Cell RNA - U-266\/84 [nTPM]":"8.9","Cell RNA - U-698 [nTPM]":"25.8","Cell RNA - U-87 MG [nTPM]":"8.6","Cell RNA - U-937 [nTPM]":"24.0","Cell RNA - WM-115 [nTPM]":"30.5","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.3","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.3","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.1","Brain RNA - midbrain [nTPM]":"0.2","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"1.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"1.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"3.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.2","Single Cell Type RNA - Endothelial cells [nTPM]":"1.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"3.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.0","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"13.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"5.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"2.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"2.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"11.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.1","Single Cell Type RNA - Spermatocytes [nTPM]":"22.8","Single Cell Type RNA - Spermatogonia [nTPM]":"16.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"2.3","Single Cell Type RNA - Theca cells [nTPM]":"0.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.3","Single Cell Type RNA - Urothelial cells [nTPM]":"1.9"},{"Gene":"KIT","Gene synonym":["C-Kit","CD117","PBT","SCFR"],"Ensembl":"ENSG00000157404","Gene description":"KIT proto-oncogene, receptor tyrosine kinase","Uniprot":["P10721"],"Chromosome":"4","Position":"54657918-54740715","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"breast":"114.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"83.1","granulocytes":"529.3","Inhibitory neurons":"111.2","Ionocytes":"101.7","Melanocytes":"211.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"28.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"7","RNA blood cell specific nTPM":{"basophil":"20.3","eosinophil":"12.8","NK-cell":"13.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"20.3","NK-cells":"13.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"HEL":"247.2","HMC-1":"496.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003288","HPA004471","CAB068253","CAB072867","HPA073252"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"49000000","Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 5: Breast - Unknown function","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 60: Granulocytes - Receptor signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB003288":"AB_2335702","CAB068253":"AB_2665717","CAB072867":"AB_2665718","HPA004471":"AB_1078431","HPA073252":"AB_2686589"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.04e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.19e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.63e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.34e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.30e-1"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"8.2","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"6.4","Tissue RNA - breast [nTPM]":"114.9","Tissue RNA - cerebellum [nTPM]":"21.4","Tissue RNA - cerebral cortex [nTPM]":"6.5","Tissue RNA - cervix [nTPM]":"17.6","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"13.5","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"9.6","Tissue RNA - epididymis [nTPM]":"5.9","Tissue RNA - esophagus [nTPM]":"13.0","Tissue RNA - fallopian tube [nTPM]":"2.9","Tissue RNA - gallbladder [nTPM]":"20.3","Tissue RNA - heart muscle [nTPM]":"3.4","Tissue RNA - hippocampal formation [nTPM]":"23.9","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"12.4","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"21.8","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"6.8","Tissue RNA - midbrain [nTPM]":"12.3","Tissue RNA - ovary [nTPM]":"45.0","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"10.0","Tissue RNA - pons [nTPM]":"8.8","Tissue RNA - prostate [nTPM]":"5.6","Tissue RNA - rectum [nTPM]":"16.0","Tissue RNA - retina [nTPM]":"3.2","Tissue RNA - salivary gland [nTPM]":"21.4","Tissue RNA - seminal vesicle [nTPM]":"8.7","Tissue RNA - skeletal muscle [nTPM]":"1.1","Tissue RNA - skin 1 [nTPM]":"24.5","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"10.1","Tissue RNA - spinal cord [nTPM]":"5.9","Tissue RNA - spleen [nTPM]":"5.0","Tissue RNA - stomach 1 [nTPM]":"17.4","Tissue RNA - testis [nTPM]":"6.2","Tissue RNA - thalamus [nTPM]":"16.7","Tissue RNA - thymus [nTPM]":"3.1","Tissue RNA - thyroid gland [nTPM]":"47.1","Tissue RNA - tongue [nTPM]":"6.9","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"14.5","Tissue RNA - vagina [nTPM]":"4.9","Tissue RNA - white matter [nTPM]":"5.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"3.9","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.7","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.8","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"7.3","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"2.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"10.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"5.9","Cell RNA - HEL [nTPM]":"247.2","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"496.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"28.4","Cell RNA - JURKAT [nTPM]":"4.3","Cell RNA - K-562 [nTPM]":"3.5","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"1.4","Cell RNA - NB-4 [nTPM]":"2.5","Cell RNA - NTERA-2 [nTPM]":"6.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"24.2","Cell RNA - SCLC-21H [nTPM]":"6.0","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"14.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.6","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.5","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"4.9","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.6","Blood RNA - basophil [nTPM]":"20.3","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"12.8","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"2.3","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.9","Blood RNA - myeloid DC [nTPM]":"2.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"13.1","Blood RNA - non-classical monocyte [nTPM]":"1.4","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"8.2","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"21.4","Brain RNA - cerebral cortex [nTPM]":"6.5","Brain RNA - hippocampal formation [nTPM]":"23.9","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"6.8","Brain RNA - midbrain [nTPM]":"12.3","Brain RNA - pons [nTPM]":"8.8","Brain RNA - spinal cord [nTPM]":"5.9","Brain RNA - thalamus [nTPM]":"16.7","Brain RNA - white matter [nTPM]":"5.1","Single Cell Type RNA - Adipocytes [nTPM]":"7.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.9","Single Cell Type RNA - Astrocytes [nTPM]":"9.8","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"83.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"59.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"3.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"5.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"9.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"15.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.7","Single Cell Type RNA - granulocytes [nTPM]":"529.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.8","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"111.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"101.7","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"4.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"1.6","Single Cell Type RNA - Melanocytes [nTPM]":"211.7","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"2.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"16.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"8.8","Single Cell Type RNA - Theca cells [nTPM]":"63.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"KLF4","Gene synonym":["EZF","GKLF"],"Ensembl":"ENSG00000136826","Gene description":"Kruppel like factor 4","Uniprot":["O43474"],"Chromosome":"9","Position":"107484852-107490482","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skin 1":"254.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"1054.7","Basal squamous epithelial cells":"832.1","Distal enterocytes":"789.2","Intestinal goblet cells":"710.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"intermediate monocyte":"1.0","non-classical monocyte":"1.0"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"39.2","hTCEpi":"84.4","hTERT-HME1":"54.5","OE19":"47.2","U-2197":"111.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002926"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA002926":"AB_1852541"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.58e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.44e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.49e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.93e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.13e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.32e-2"},"Tissue RNA - adipose tissue [nTPM]":"73.5","Tissue RNA - adrenal gland [nTPM]":"23.9","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"21.0","Tissue RNA - basal ganglia [nTPM]":"4.7","Tissue RNA - bone marrow [nTPM]":"50.5","Tissue RNA - breast [nTPM]":"63.7","Tissue RNA - cerebellum [nTPM]":"4.0","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"53.2","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"87.3","Tissue RNA - duodenum [nTPM]":"28.4","Tissue RNA - endometrium 1 [nTPM]":"16.0","Tissue RNA - epididymis [nTPM]":"5.6","Tissue RNA - esophagus [nTPM]":"102.1","Tissue RNA - fallopian tube [nTPM]":"43.0","Tissue RNA - gallbladder [nTPM]":"44.3","Tissue RNA - heart muscle [nTPM]":"31.0","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"5.1","Tissue RNA - kidney [nTPM]":"6.2","Tissue RNA - liver [nTPM]":"12.4","Tissue RNA - lung [nTPM]":"44.8","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"5.0","Tissue RNA - midbrain [nTPM]":"4.7","Tissue RNA - ovary [nTPM]":"29.0","Tissue RNA - pancreas [nTPM]":"7.0","Tissue RNA - parathyroid gland [nTPM]":"5.7","Tissue RNA - pituitary gland [nTPM]":"4.9","Tissue RNA - placenta [nTPM]":"32.4","Tissue RNA - pons [nTPM]":"5.0","Tissue RNA - prostate [nTPM]":"16.7","Tissue RNA - rectum [nTPM]":"96.0","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"27.5","Tissue RNA - seminal vesicle [nTPM]":"7.6","Tissue RNA - skeletal muscle [nTPM]":"14.2","Tissue RNA - skin 1 [nTPM]":"254.7","Tissue RNA - small intestine [nTPM]":"40.5","Tissue RNA - smooth muscle [nTPM]":"40.6","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"24.1","Tissue RNA - stomach 1 [nTPM]":"58.0","Tissue RNA - testis [nTPM]":"17.8","Tissue RNA - thalamus [nTPM]":"6.0","Tissue RNA - thymus [nTPM]":"17.0","Tissue RNA - thyroid gland [nTPM]":"25.2","Tissue RNA - tongue [nTPM]":"23.2","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"43.9","Tissue RNA - vagina [nTPM]":"58.9","Tissue RNA - white matter [nTPM]":"4.0","Cell RNA - A-431 [nTPM]":"13.3","Cell RNA - A549 [nTPM]":"3.9","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"16.6","Cell RNA - ASC TERT1 [nTPM]":"39.2","Cell RNA - BEWO [nTPM]":"5.2","Cell RNA - BJ [nTPM]":"4.4","Cell RNA - BJ hTERT+ [nTPM]":"27.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.1","Cell RNA - CACO-2 [nTPM]":"1.0","Cell RNA - CAPAN-2 [nTPM]":"18.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.6","Cell RNA - fHDF\/TERT166 [nTPM]":"6.9","Cell RNA - GAMG [nTPM]":"23.7","Cell RNA - HaCaT [nTPM]":"8.7","Cell RNA - HAP1 [nTPM]":"6.1","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"3.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"7.5","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"21.6","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"5.0","Cell RNA - hTCEpi [nTPM]":"84.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.0","Cell RNA - hTERT-HME1 [nTPM]":"54.5","Cell RNA - hTERT-RPE1 [nTPM]":"1.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.6","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"4.1","Cell RNA - MCF7 [nTPM]":"7.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"47.2","Cell RNA - PC-3 [nTPM]":"25.2","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"1.6","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"3.7","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"4.0","Cell RNA - SK-BR-3 [nTPM]":"11.8","Cell RNA - SK-MEL-30 [nTPM]":"15.2","Cell RNA - SuSa [nTPM]":"12.7","Cell RNA - T-47d [nTPM]":"1.3","Cell RNA - THP-1 [nTPM]":"5.4","Cell RNA - TIME [nTPM]":"3.5","Cell RNA - U-138 MG [nTPM]":"3.6","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"111.5","Cell RNA - U-251 MG [nTPM]":"2.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.4","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.9","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"4.7","Brain RNA - cerebellum [nTPM]":"4.0","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"5.1","Brain RNA - medulla oblongata [nTPM]":"5.0","Brain RNA - midbrain [nTPM]":"4.7","Brain RNA - pons [nTPM]":"5.0","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"6.0","Brain RNA - white matter [nTPM]":"4.0","Single Cell Type RNA - Adipocytes [nTPM]":"1054.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"41.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"32.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"436.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"284.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"143.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"832.1","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"206.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"205.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"70.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"35.8","Single Cell Type RNA - Club cells [nTPM]":"71.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"49.1","Single Cell Type RNA - dendritic cells [nTPM]":"15.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"789.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.4","Single Cell Type RNA - Early spermatids [nTPM]":"263.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"154.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"216.0","Single Cell Type RNA - Endothelial cells [nTPM]":"336.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"123.8","Single Cell Type RNA - Erythroid cells [nTPM]":"4.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"38.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"75.5","Single Cell Type RNA - Fibroblasts [nTPM]":"463.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"537.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"297.4","Single Cell Type RNA - granulocytes [nTPM]":"54.7","Single Cell Type RNA - Granulosa cells [nTPM]":"4.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"216.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"89.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"710.9","Single Cell Type RNA - Ionocytes [nTPM]":"83.4","Single Cell Type RNA - Kupffer cells [nTPM]":"232.9","Single Cell Type RNA - Langerhans cells [nTPM]":"282.0","Single Cell Type RNA - Late spermatids [nTPM]":"163.0","Single Cell Type RNA - Leydig cells [nTPM]":"143.8","Single Cell Type RNA - Macrophages [nTPM]":"401.0","Single Cell Type RNA - Melanocytes [nTPM]":"206.3","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"36.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.3","Single Cell Type RNA - Paneth cells [nTPM]":"540.9","Single Cell Type RNA - Peritubular cells [nTPM]":"60.5","Single Cell Type RNA - Plasma cells [nTPM]":"38.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"187.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"198.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"46.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"463.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"130.0","Single Cell Type RNA - Spermatocytes [nTPM]":"21.6","Single Cell Type RNA - Spermatogonia [nTPM]":"15.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"639.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"674.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"107.9","Single Cell Type RNA - T-cells [nTPM]":"26.8","Single Cell Type RNA - Theca cells [nTPM]":"63.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"332.6","Single Cell Type RNA - Urothelial cells [nTPM]":"236.8"},{"Gene":"KMT2A","Gene synonym":["ALL-1","CXXC7","HRX","HTRX1","MLL","MLL1A","TRX1"],"Ensembl":"ENSG00000118058","Gene description":"Lysine methyltransferase 2A","Uniprot":["Q03164"],"Chromosome":"11","Position":"118436490-118526832","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Apoptosis","Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017794","CAB024270","HPA044910"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017794":null,"CAB024270":null,"HPA044910":"AB_2679141"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.52e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.91e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.90e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.9","Tissue RNA - adrenal gland [nTPM]":"6.7","Tissue RNA - amygdala [nTPM]":"8.0","Tissue RNA - appendix [nTPM]":"8.5","Tissue RNA - basal ganglia [nTPM]":"8.6","Tissue RNA - bone marrow [nTPM]":"19.5","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"21.2","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"10.3","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"10.8","Tissue RNA - duodenum [nTPM]":"5.4","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"8.2","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"6.4","Tissue RNA - heart muscle [nTPM]":"6.5","Tissue RNA - hippocampal formation [nTPM]":"7.4","Tissue RNA - hypothalamus [nTPM]":"9.6","Tissue RNA - kidney [nTPM]":"6.7","Tissue RNA - liver [nTPM]":"6.0","Tissue RNA - lung [nTPM]":"10.5","Tissue RNA - lymph node [nTPM]":"12.4","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"6.3","Tissue RNA - ovary [nTPM]":"21.2","Tissue RNA - pancreas [nTPM]":"11.1","Tissue RNA - parathyroid gland [nTPM]":"9.8","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"6.6","Tissue RNA - prostate [nTPM]":"9.2","Tissue RNA - rectum [nTPM]":"6.4","Tissue RNA - retina [nTPM]":"23.9","Tissue RNA - salivary gland [nTPM]":"9.4","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"7.4","Tissue RNA - skin 1 [nTPM]":"10.4","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"7.6","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"9.7","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"5.3","Tissue RNA - thalamus [nTPM]":"7.0","Tissue RNA - thymus [nTPM]":"14.1","Tissue RNA - thyroid gland [nTPM]":"9.9","Tissue RNA - tongue [nTPM]":"8.4","Tissue RNA - tonsil [nTPM]":"11.3","Tissue RNA - urinary bladder [nTPM]":"10.7","Tissue RNA - vagina [nTPM]":"9.3","Tissue RNA - white matter [nTPM]":"11.9","Cell RNA - A-431 [nTPM]":"17.9","Cell RNA - A549 [nTPM]":"8.6","Cell RNA - AF22 [nTPM]":"20.1","Cell RNA - AN3-CA [nTPM]":"14.5","Cell RNA - ASC diff [nTPM]":"11.1","Cell RNA - ASC TERT1 [nTPM]":"16.1","Cell RNA - BEWO [nTPM]":"6.2","Cell RNA - BJ [nTPM]":"8.7","Cell RNA - BJ hTERT+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"9.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"9.6","Cell RNA - CACO-2 [nTPM]":"17.3","Cell RNA - CAPAN-2 [nTPM]":"11.4","Cell RNA - Daudi [nTPM]":"23.1","Cell RNA - EFO-21 [nTPM]":"15.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"14.6","Cell RNA - HaCaT [nTPM]":"16.0","Cell RNA - HAP1 [nTPM]":"22.9","Cell RNA - HBEC3-KT [nTPM]":"7.2","Cell RNA - HBF TERT88 [nTPM]":"17.9","Cell RNA - HDLM-2 [nTPM]":"26.0","Cell RNA - HEK 293 [nTPM]":"10.0","Cell RNA - HEL [nTPM]":"45.7","Cell RNA - HeLa [nTPM]":"8.9","Cell RNA - Hep G2 [nTPM]":"9.3","Cell RNA - HHSteC [nTPM]":"6.1","Cell RNA - HL-60 [nTPM]":"28.5","Cell RNA - HMC-1 [nTPM]":"7.8","Cell RNA - HSkMC [nTPM]":"7.2","Cell RNA - hTCEpi [nTPM]":"7.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.3","Cell RNA - hTERT-HME1 [nTPM]":"24.0","Cell RNA - hTERT-RPE1 [nTPM]":"8.9","Cell RNA - HUVEC TERT2 [nTPM]":"12.8","Cell RNA - JURKAT [nTPM]":"13.3","Cell RNA - K-562 [nTPM]":"32.8","Cell RNA - Karpas-707 [nTPM]":"18.8","Cell RNA - LHCN-M2 [nTPM]":"9.2","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"18.2","Cell RNA - NB-4 [nTPM]":"12.7","Cell RNA - NTERA-2 [nTPM]":"13.6","Cell RNA - OE19 [nTPM]":"6.6","Cell RNA - PC-3 [nTPM]":"13.7","Cell RNA - REH [nTPM]":"13.8","Cell RNA - RH-30 [nTPM]":"21.9","Cell RNA - RPMI-8226 [nTPM]":"6.9","Cell RNA - RPTEC TERT1 [nTPM]":"9.8","Cell RNA - RT4 [nTPM]":"13.8","Cell RNA - SCLC-21H [nTPM]":"18.0","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"22.0","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"3.9","Cell RNA - SuSa [nTPM]":"9.8","Cell RNA - T-47d [nTPM]":"11.9","Cell RNA - THP-1 [nTPM]":"9.1","Cell RNA - TIME [nTPM]":"20.4","Cell RNA - U-138 MG [nTPM]":"14.1","Cell RNA - U-2 OS [nTPM]":"12.7","Cell RNA - U-2197 [nTPM]":"9.4","Cell RNA - U-251 MG [nTPM]":"14.7","Cell RNA - U-266\/70 [nTPM]":"5.1","Cell RNA - U-266\/84 [nTPM]":"4.4","Cell RNA - U-698 [nTPM]":"15.6","Cell RNA - U-87 MG [nTPM]":"4.7","Cell RNA - U-937 [nTPM]":"17.6","Cell RNA - WM-115 [nTPM]":"8.3","Blood RNA - basophil [nTPM]":"2.1","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.2","Blood RNA - neutrophil [nTPM]":"0.5","Blood RNA - NK-cell [nTPM]":"2.0","Blood RNA - non-classical monocyte [nTPM]":"0.7","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"8.0","Brain RNA - basal ganglia [nTPM]":"8.6","Brain RNA - cerebellum [nTPM]":"21.2","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"7.4","Brain RNA - hypothalamus [nTPM]":"9.6","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"6.3","Brain RNA - pons [nTPM]":"6.6","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"7.0","Brain RNA - white matter [nTPM]":"11.9","Single Cell Type RNA - Adipocytes [nTPM]":"87.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"70.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"65.8","Single Cell Type RNA - Astrocytes [nTPM]":"93.4","Single Cell Type RNA - B-cells [nTPM]":"83.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"86.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"67.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"64.9","Single Cell Type RNA - Bipolar cells [nTPM]":"158.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"76.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"73.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"44.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"32.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"152.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"13.9","Single Cell Type RNA - dendritic cells [nTPM]":"81.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"26.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"33.0","Single Cell Type RNA - Early spermatids [nTPM]":"10.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"62.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.4","Single Cell Type RNA - Endothelial cells [nTPM]":"74.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.4","Single Cell Type RNA - Erythroid cells [nTPM]":"67.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"146.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"25.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.2","Single Cell Type RNA - Fibroblasts [nTPM]":"65.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"85.2","Single Cell Type RNA - granulocytes [nTPM]":"29.0","Single Cell Type RNA - Granulosa cells [nTPM]":"57.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"60.0","Single Cell Type RNA - Hepatocytes [nTPM]":"27.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"16.8","Single Cell Type RNA - Horizontal cells [nTPM]":"195.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"170.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.6","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"37.0","Single Cell Type RNA - Langerhans cells [nTPM]":"63.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.8","Single Cell Type RNA - Leydig cells [nTPM]":"66.8","Single Cell Type RNA - Macrophages [nTPM]":"44.8","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"62.8","Single Cell Type RNA - monocytes [nTPM]":"49.9","Single Cell Type RNA - Muller glia cells [nTPM]":"98.9","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"106.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"131.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"28.2","Single Cell Type RNA - Paneth cells [nTPM]":"20.1","Single Cell Type RNA - Peritubular cells [nTPM]":"78.6","Single Cell Type RNA - Plasma cells [nTPM]":"83.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"88.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"52.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"152.4","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"113.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"84.6","Single Cell Type RNA - Spermatocytes [nTPM]":"25.5","Single Cell Type RNA - Spermatogonia [nTPM]":"30.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"46.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"80.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"6.0","Single Cell Type RNA - T-cells [nTPM]":"102.8","Single Cell Type RNA - Theca cells [nTPM]":"55.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"30.6","Single Cell Type RNA - Urothelial cells [nTPM]":"64.8"},{"Gene":"KMT2B","Gene synonym":["CXXC10","HRX2","KIAA0304","MLL1B","MLL2","MLL4","TRX2","WBP7"],"Ensembl":"ENSG00000272333","Gene description":"Lysine methyltransferase 2B","Uniprot":["Q9UMN6"],"Chromosome":"19","Position":"35717973-35738878","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dystonia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Bipolar cells":"64.5","Rod photoreceptor cells":"71.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006487"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 43: Testis - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA006487":"AB_1080587"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.6","Tissue RNA - adrenal gland [nTPM]":"10.1","Tissue RNA - amygdala [nTPM]":"15.4","Tissue RNA - appendix [nTPM]":"9.8","Tissue RNA - basal ganglia [nTPM]":"15.7","Tissue RNA - bone marrow [nTPM]":"14.3","Tissue RNA - breast [nTPM]":"11.8","Tissue RNA - cerebellum [nTPM]":"17.2","Tissue RNA - cerebral cortex [nTPM]":"22.9","Tissue RNA - cervix [nTPM]":"12.9","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"13.6","Tissue RNA - duodenum [nTPM]":"9.8","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"12.8","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"6.8","Tissue RNA - heart muscle [nTPM]":"8.4","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"14.8","Tissue RNA - kidney [nTPM]":"10.3","Tissue RNA - liver [nTPM]":"10.0","Tissue RNA - lung [nTPM]":"12.1","Tissue RNA - lymph node [nTPM]":"14.5","Tissue RNA - medulla oblongata [nTPM]":"15.4","Tissue RNA - midbrain [nTPM]":"14.4","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"16.0","Tissue RNA - parathyroid gland [nTPM]":"5.1","Tissue RNA - pituitary gland [nTPM]":"14.5","Tissue RNA - placenta [nTPM]":"5.8","Tissue RNA - pons [nTPM]":"14.7","Tissue RNA - prostate [nTPM]":"13.4","Tissue RNA - rectum [nTPM]":"3.9","Tissue RNA - retina [nTPM]":"5.8","Tissue RNA - salivary gland [nTPM]":"13.3","Tissue RNA - seminal vesicle [nTPM]":"5.8","Tissue RNA - skeletal muscle [nTPM]":"16.1","Tissue RNA - skin 1 [nTPM]":"18.8","Tissue RNA - small intestine [nTPM]":"14.5","Tissue RNA - smooth muscle [nTPM]":"4.5","Tissue RNA - spinal cord [nTPM]":"12.4","Tissue RNA - spleen [nTPM]":"15.6","Tissue RNA - stomach 1 [nTPM]":"12.7","Tissue RNA - testis [nTPM]":"22.5","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"16.6","Tissue RNA - tongue [nTPM]":"5.0","Tissue RNA - tonsil [nTPM]":"6.8","Tissue RNA - urinary bladder [nTPM]":"12.6","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"16.0","Cell RNA - A-431 [nTPM]":"16.7","Cell RNA - A549 [nTPM]":"36.7","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"17.3","Cell RNA - ASC diff [nTPM]":"6.0","Cell RNA - ASC TERT1 [nTPM]":"4.3","Cell RNA - BEWO [nTPM]":"11.0","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"4.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.0","Cell RNA - CACO-2 [nTPM]":"25.3","Cell RNA - CAPAN-2 [nTPM]":"7.4","Cell RNA - Daudi [nTPM]":"15.5","Cell RNA - EFO-21 [nTPM]":"11.8","Cell RNA - fHDF\/TERT166 [nTPM]":"5.1","Cell RNA - GAMG [nTPM]":"8.5","Cell RNA - HaCaT [nTPM]":"10.8","Cell RNA - HAP1 [nTPM]":"11.3","Cell RNA - HBEC3-KT [nTPM]":"5.2","Cell RNA - HBF TERT88 [nTPM]":"4.2","Cell RNA - HDLM-2 [nTPM]":"21.2","Cell RNA - HEK 293 [nTPM]":"13.6","Cell RNA - HEL [nTPM]":"29.7","Cell RNA - HeLa [nTPM]":"20.2","Cell RNA - Hep G2 [nTPM]":"24.4","Cell RNA - HHSteC [nTPM]":"8.6","Cell RNA - HL-60 [nTPM]":"17.4","Cell RNA - HMC-1 [nTPM]":"26.1","Cell RNA - HSkMC [nTPM]":"6.9","Cell RNA - hTCEpi [nTPM]":"9.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"8.9","Cell RNA - hTERT-HME1 [nTPM]":"10.7","Cell RNA - hTERT-RPE1 [nTPM]":"6.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.7","Cell RNA - JURKAT [nTPM]":"13.5","Cell RNA - K-562 [nTPM]":"22.5","Cell RNA - Karpas-707 [nTPM]":"15.8","Cell RNA - LHCN-M2 [nTPM]":"6.4","Cell RNA - MCF7 [nTPM]":"34.1","Cell RNA - MOLT-4 [nTPM]":"15.9","Cell RNA - NB-4 [nTPM]":"24.4","Cell RNA - NTERA-2 [nTPM]":"12.0","Cell RNA - OE19 [nTPM]":"18.8","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"19.8","Cell RNA - RH-30 [nTPM]":"8.9","Cell RNA - RPMI-8226 [nTPM]":"7.6","Cell RNA - RPTEC TERT1 [nTPM]":"7.8","Cell RNA - RT4 [nTPM]":"21.3","Cell RNA - SCLC-21H [nTPM]":"14.0","Cell RNA - SH-SY5Y [nTPM]":"10.0","Cell RNA - SiHa [nTPM]":"13.5","Cell RNA - SK-BR-3 [nTPM]":"20.6","Cell RNA - SK-MEL-30 [nTPM]":"11.3","Cell RNA - SuSa [nTPM]":"7.9","Cell RNA - T-47d [nTPM]":"11.8","Cell RNA - THP-1 [nTPM]":"21.3","Cell RNA - TIME [nTPM]":"12.5","Cell RNA - U-138 MG [nTPM]":"16.3","Cell RNA - U-2 OS [nTPM]":"17.0","Cell RNA - U-2197 [nTPM]":"10.5","Cell RNA - U-251 MG [nTPM]":"17.4","Cell RNA - U-266\/70 [nTPM]":"22.2","Cell RNA - U-266\/84 [nTPM]":"15.7","Cell RNA - U-698 [nTPM]":"12.4","Cell RNA - U-87 MG [nTPM]":"8.5","Cell RNA - U-937 [nTPM]":"18.8","Cell RNA - WM-115 [nTPM]":"12.2","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.5","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"0.6","Blood RNA - memory CD8 T-cell [nTPM]":"0.7","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"1.8","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"15.4","Brain RNA - basal ganglia [nTPM]":"15.7","Brain RNA - cerebellum [nTPM]":"17.2","Brain RNA - cerebral cortex [nTPM]":"22.9","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"14.8","Brain RNA - medulla oblongata [nTPM]":"15.4","Brain RNA - midbrain [nTPM]":"14.4","Brain RNA - pons [nTPM]":"14.7","Brain RNA - spinal cord [nTPM]":"12.4","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"16.0","Single Cell Type RNA - Adipocytes [nTPM]":"24.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.4","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"18.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"12.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"64.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"14.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"6.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.5","Single Cell Type RNA - dendritic cells [nTPM]":"27.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"6.4","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"17.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.6","Single Cell Type RNA - Endothelial cells [nTPM]":"15.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"20.3","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"11.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"12.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.0","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"30.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"11.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"8.4","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"11.8","Single Cell Type RNA - Langerhans cells [nTPM]":"7.1","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"13.4","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"9.5","Single Cell Type RNA - Muller glia cells [nTPM]":"25.7","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"7.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"10.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.4","Single Cell Type RNA - Paneth cells [nTPM]":"16.7","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"17.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"71.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"26.5","Single Cell Type RNA - Spermatogonia [nTPM]":"38.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - T-cells [nTPM]":"20.6","Single Cell Type RNA - Theca cells [nTPM]":"30.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.3","Single Cell Type RNA - Urothelial cells [nTPM]":"14.8"},{"Gene":"KMT2C","Gene synonym":["HALR","KIAA1506","MLL3"],"Ensembl":"ENSG00000055609","Gene description":"Lysine methyltransferase 2C","Uniprot":["Q8NEZ4"],"Chromosome":"7","Position":"152134922-152436641","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Acyltransferase","Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocytes":"363.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"15.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA074736"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA074736":"AB_2686709"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.23e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.64e-1"},"Tissue RNA - adipose tissue [nTPM]":"12.7","Tissue RNA - adrenal gland [nTPM]":"11.2","Tissue RNA - amygdala [nTPM]":"16.7","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"25.7","Tissue RNA - bone marrow [nTPM]":"16.4","Tissue RNA - breast [nTPM]":"12.9","Tissue RNA - cerebellum [nTPM]":"16.7","Tissue RNA - cerebral cortex [nTPM]":"15.7","Tissue RNA - cervix [nTPM]":"15.3","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"13.1","Tissue RNA - duodenum [nTPM]":"5.7","Tissue RNA - endometrium 1 [nTPM]":"14.3","Tissue RNA - epididymis [nTPM]":"13.7","Tissue RNA - esophagus [nTPM]":"14.1","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"10.2","Tissue RNA - hippocampal formation [nTPM]":"13.0","Tissue RNA - hypothalamus [nTPM]":"18.9","Tissue RNA - kidney [nTPM]":"8.9","Tissue RNA - liver [nTPM]":"10.4","Tissue RNA - lung [nTPM]":"12.7","Tissue RNA - lymph node [nTPM]":"8.1","Tissue RNA - medulla oblongata [nTPM]":"25.3","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"16.8","Tissue RNA - pancreas [nTPM]":"18.5","Tissue RNA - parathyroid gland [nTPM]":"12.4","Tissue RNA - pituitary gland [nTPM]":"12.1","Tissue RNA - placenta [nTPM]":"10.3","Tissue RNA - pons [nTPM]":"20.6","Tissue RNA - prostate [nTPM]":"9.3","Tissue RNA - rectum [nTPM]":"7.6","Tissue RNA - retina [nTPM]":"21.7","Tissue RNA - salivary gland [nTPM]":"14.2","Tissue RNA - seminal vesicle [nTPM]":"9.0","Tissue RNA - skeletal muscle [nTPM]":"25.9","Tissue RNA - skin 1 [nTPM]":"17.6","Tissue RNA - small intestine [nTPM]":"12.8","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"12.2","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"19.1","Tissue RNA - thymus [nTPM]":"16.1","Tissue RNA - thyroid gland [nTPM]":"14.6","Tissue RNA - tongue [nTPM]":"16.9","Tissue RNA - tonsil [nTPM]":"9.5","Tissue RNA - urinary bladder [nTPM]":"11.3","Tissue RNA - vagina [nTPM]":"12.7","Tissue RNA - white matter [nTPM]":"28.6","Cell RNA - A-431 [nTPM]":"13.4","Cell RNA - A549 [nTPM]":"6.1","Cell RNA - AF22 [nTPM]":"11.6","Cell RNA - AN3-CA [nTPM]":"11.7","Cell RNA - ASC diff [nTPM]":"19.0","Cell RNA - ASC TERT1 [nTPM]":"13.9","Cell RNA - BEWO [nTPM]":"10.2","Cell RNA - BJ [nTPM]":"4.7","Cell RNA - BJ hTERT+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.5","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"4.7","Cell RNA - Daudi [nTPM]":"22.4","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"11.3","Cell RNA - GAMG [nTPM]":"9.2","Cell RNA - HaCaT [nTPM]":"5.2","Cell RNA - HAP1 [nTPM]":"14.3","Cell RNA - HBEC3-KT [nTPM]":"7.5","Cell RNA - HBF TERT88 [nTPM]":"9.2","Cell RNA - HDLM-2 [nTPM]":"12.7","Cell RNA - HEK 293 [nTPM]":"6.5","Cell RNA - HEL [nTPM]":"14.0","Cell RNA - HeLa [nTPM]":"7.3","Cell RNA - Hep G2 [nTPM]":"4.5","Cell RNA - HHSteC [nTPM]":"8.9","Cell RNA - HL-60 [nTPM]":"22.9","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"6.6","Cell RNA - hTCEpi [nTPM]":"9.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"7.1","Cell RNA - hTERT-HME1 [nTPM]":"8.2","Cell RNA - hTERT-RPE1 [nTPM]":"7.2","Cell RNA - HUVEC TERT2 [nTPM]":"8.4","Cell RNA - JURKAT [nTPM]":"9.7","Cell RNA - K-562 [nTPM]":"22.5","Cell RNA - Karpas-707 [nTPM]":"15.0","Cell RNA - LHCN-M2 [nTPM]":"11.7","Cell RNA - MCF7 [nTPM]":"12.7","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"11.1","Cell RNA - NTERA-2 [nTPM]":"6.8","Cell RNA - OE19 [nTPM]":"8.5","Cell RNA - PC-3 [nTPM]":"7.9","Cell RNA - REH [nTPM]":"9.5","Cell RNA - RH-30 [nTPM]":"12.3","Cell RNA - RPMI-8226 [nTPM]":"8.4","Cell RNA - RPTEC TERT1 [nTPM]":"5.8","Cell RNA - RT4 [nTPM]":"10.9","Cell RNA - SCLC-21H [nTPM]":"19.6","Cell RNA - SH-SY5Y [nTPM]":"12.8","Cell RNA - SiHa [nTPM]":"13.4","Cell RNA - SK-BR-3 [nTPM]":"15.8","Cell RNA - SK-MEL-30 [nTPM]":"6.3","Cell RNA - SuSa [nTPM]":"10.6","Cell RNA - T-47d [nTPM]":"4.6","Cell RNA - THP-1 [nTPM]":"15.7","Cell RNA - TIME [nTPM]":"12.8","Cell RNA - U-138 MG [nTPM]":"8.0","Cell RNA - U-2 OS [nTPM]":"4.4","Cell RNA - U-2197 [nTPM]":"9.0","Cell RNA - U-251 MG [nTPM]":"8.9","Cell RNA - U-266\/70 [nTPM]":"15.3","Cell RNA - U-266\/84 [nTPM]":"7.7","Cell RNA - U-698 [nTPM]":"22.4","Cell RNA - U-87 MG [nTPM]":"10.7","Cell RNA - U-937 [nTPM]":"14.7","Cell RNA - WM-115 [nTPM]":"8.4","Blood RNA - basophil [nTPM]":"6.1","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"4.4","Blood RNA - gdT-cell [nTPM]":"1.9","Blood RNA - intermediate monocyte [nTPM]":"2.7","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"6.9","Blood RNA - memory CD4 T-cell [nTPM]":"2.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.4","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"1.4","Blood RNA - neutrophil [nTPM]":"15.2","Blood RNA - NK-cell [nTPM]":"2.2","Blood RNA - non-classical monocyte [nTPM]":"2.6","Blood RNA - plasmacytoid DC [nTPM]":"3.7","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"0.8","Brain RNA - amygdala [nTPM]":"16.7","Brain RNA - basal ganglia [nTPM]":"25.7","Brain RNA - cerebellum [nTPM]":"16.7","Brain RNA - cerebral cortex [nTPM]":"15.7","Brain RNA - hippocampal formation [nTPM]":"13.0","Brain RNA - hypothalamus [nTPM]":"18.9","Brain RNA - medulla oblongata [nTPM]":"25.3","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"20.6","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"19.1","Brain RNA - white matter [nTPM]":"28.6","Single Cell Type RNA - Adipocytes [nTPM]":"62.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"76.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"71.9","Single Cell Type RNA - Astrocytes [nTPM]":"292.8","Single Cell Type RNA - B-cells [nTPM]":"75.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"89.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"62.0","Single Cell Type RNA - Bipolar cells [nTPM]":"89.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"35.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"65.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"72.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"46.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"173.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.0","Single Cell Type RNA - dendritic cells [nTPM]":"61.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"61.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"37.6","Single Cell Type RNA - Early spermatids [nTPM]":"32.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"94.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"92.1","Single Cell Type RNA - Endothelial cells [nTPM]":"58.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.9","Single Cell Type RNA - Erythroid cells [nTPM]":"55.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"180.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"33.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"51.7","Single Cell Type RNA - Fibroblasts [nTPM]":"58.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"89.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"200.5","Single Cell Type RNA - granulocytes [nTPM]":"65.2","Single Cell Type RNA - Granulosa cells [nTPM]":"52.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.7","Single Cell Type RNA - Hepatocytes [nTPM]":"46.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"33.7","Single Cell Type RNA - Horizontal cells [nTPM]":"80.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"172.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.5","Single Cell Type RNA - Ionocytes [nTPM]":"42.7","Single Cell Type RNA - Kupffer cells [nTPM]":"54.7","Single Cell Type RNA - Langerhans cells [nTPM]":"79.6","Single Cell Type RNA - Late spermatids [nTPM]":"17.3","Single Cell Type RNA - Leydig cells [nTPM]":"67.4","Single Cell Type RNA - Macrophages [nTPM]":"90.5","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"202.4","Single Cell Type RNA - monocytes [nTPM]":"77.1","Single Cell Type RNA - Muller glia cells [nTPM]":"57.7","Single Cell Type RNA - NK-cells [nTPM]":"59.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"299.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"363.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.6","Single Cell Type RNA - Paneth cells [nTPM]":"49.0","Single Cell Type RNA - Peritubular cells [nTPM]":"60.2","Single Cell Type RNA - Plasma cells [nTPM]":"90.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"53.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"36.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"46.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"83.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"55.5","Single Cell Type RNA - Spermatocytes [nTPM]":"42.3","Single Cell Type RNA - Spermatogonia [nTPM]":"33.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"80.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"96.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"127.2","Single Cell Type RNA - T-cells [nTPM]":"76.8","Single Cell Type RNA - Theca cells [nTPM]":"54.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"39.1","Single Cell Type RNA - Urothelial cells [nTPM]":"61.4"},{"Gene":"KMT2D","Gene synonym":["ALR","CAGL114","MLL2","MLL4","TNRC21"],"Ensembl":"ENSG00000167548","Gene description":"Lysine methyltransferase 2D","Uniprot":["O14686"],"Chromosome":"12","Position":"49018978-49060794","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035977"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Neutrophils - Chromatin organization","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"HPA035977":"AB_10670673"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.33e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.07e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.91e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.23e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.60e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.9","Tissue RNA - adrenal gland [nTPM]":"21.9","Tissue RNA - amygdala [nTPM]":"14.0","Tissue RNA - appendix [nTPM]":"17.0","Tissue RNA - basal ganglia [nTPM]":"14.4","Tissue RNA - bone marrow [nTPM]":"62.1","Tissue RNA - breast [nTPM]":"20.3","Tissue RNA - cerebellum [nTPM]":"14.7","Tissue RNA - cerebral cortex [nTPM]":"18.1","Tissue RNA - cervix [nTPM]":"20.2","Tissue RNA - choroid plexus [nTPM]":"3.8","Tissue RNA - colon [nTPM]":"21.3","Tissue RNA - duodenum [nTPM]":"13.2","Tissue RNA - endometrium 1 [nTPM]":"26.9","Tissue RNA - epididymis [nTPM]":"14.4","Tissue RNA - esophagus [nTPM]":"25.5","Tissue RNA - fallopian tube [nTPM]":"24.1","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"23.7","Tissue RNA - hippocampal formation [nTPM]":"12.1","Tissue RNA - hypothalamus [nTPM]":"9.1","Tissue RNA - kidney [nTPM]":"18.2","Tissue RNA - liver [nTPM]":"20.5","Tissue RNA - lung [nTPM]":"25.1","Tissue RNA - lymph node [nTPM]":"17.5","Tissue RNA - medulla oblongata [nTPM]":"9.3","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"25.3","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"22.9","Tissue RNA - pituitary gland [nTPM]":"25.4","Tissue RNA - placenta [nTPM]":"16.2","Tissue RNA - pons [nTPM]":"8.6","Tissue RNA - prostate [nTPM]":"19.2","Tissue RNA - rectum [nTPM]":"14.7","Tissue RNA - retina [nTPM]":"48.0","Tissue RNA - salivary gland [nTPM]":"22.1","Tissue RNA - seminal vesicle [nTPM]":"16.2","Tissue RNA - skeletal muscle [nTPM]":"44.9","Tissue RNA - skin 1 [nTPM]":"30.4","Tissue RNA - small intestine [nTPM]":"27.9","Tissue RNA - smooth muscle [nTPM]":"15.5","Tissue RNA - spinal cord [nTPM]":"3.1","Tissue RNA - spleen [nTPM]":"36.6","Tissue RNA - stomach 1 [nTPM]":"25.5","Tissue RNA - testis [nTPM]":"23.6","Tissue RNA - thalamus [nTPM]":"12.7","Tissue RNA - thymus [nTPM]":"29.0","Tissue RNA - thyroid gland [nTPM]":"26.5","Tissue RNA - tongue [nTPM]":"21.9","Tissue RNA - tonsil [nTPM]":"17.2","Tissue RNA - urinary bladder [nTPM]":"19.4","Tissue RNA - vagina [nTPM]":"19.4","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"32.3","Cell RNA - A549 [nTPM]":"31.9","Cell RNA - AF22 [nTPM]":"31.0","Cell RNA - AN3-CA [nTPM]":"24.7","Cell RNA - ASC diff [nTPM]":"29.3","Cell RNA - ASC TERT1 [nTPM]":"20.4","Cell RNA - BEWO [nTPM]":"32.6","Cell RNA - BJ [nTPM]":"17.3","Cell RNA - BJ hTERT+ [nTPM]":"17.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"20.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"10.9","Cell RNA - CACO-2 [nTPM]":"54.8","Cell RNA - CAPAN-2 [nTPM]":"14.1","Cell RNA - Daudi [nTPM]":"33.4","Cell RNA - EFO-21 [nTPM]":"21.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.9","Cell RNA - GAMG [nTPM]":"14.0","Cell RNA - HaCaT [nTPM]":"21.5","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"19.9","Cell RNA - HBF TERT88 [nTPM]":"17.7","Cell RNA - HDLM-2 [nTPM]":"22.4","Cell RNA - HEK 293 [nTPM]":"26.7","Cell RNA - HEL [nTPM]":"47.2","Cell RNA - HeLa [nTPM]":"37.7","Cell RNA - Hep G2 [nTPM]":"29.9","Cell RNA - HHSteC [nTPM]":"20.5","Cell RNA - HL-60 [nTPM]":"59.1","Cell RNA - HMC-1 [nTPM]":"43.2","Cell RNA - HSkMC [nTPM]":"18.4","Cell RNA - hTCEpi [nTPM]":"25.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"30.7","Cell RNA - hTERT-HME1 [nTPM]":"32.0","Cell RNA - hTERT-RPE1 [nTPM]":"27.3","Cell RNA - HUVEC TERT2 [nTPM]":"31.8","Cell RNA - JURKAT [nTPM]":"33.2","Cell RNA - K-562 [nTPM]":"55.1","Cell RNA - Karpas-707 [nTPM]":"19.2","Cell RNA - LHCN-M2 [nTPM]":"23.7","Cell RNA - MCF7 [nTPM]":"37.4","Cell RNA - MOLT-4 [nTPM]":"26.8","Cell RNA - NB-4 [nTPM]":"48.0","Cell RNA - NTERA-2 [nTPM]":"29.9","Cell RNA - OE19 [nTPM]":"45.4","Cell RNA - PC-3 [nTPM]":"25.0","Cell RNA - REH [nTPM]":"37.4","Cell RNA - RH-30 [nTPM]":"22.4","Cell RNA - RPMI-8226 [nTPM]":"12.0","Cell RNA - RPTEC TERT1 [nTPM]":"18.1","Cell RNA - RT4 [nTPM]":"37.2","Cell RNA - SCLC-21H [nTPM]":"24.6","Cell RNA - SH-SY5Y [nTPM]":"21.2","Cell RNA - SiHa [nTPM]":"28.1","Cell RNA - SK-BR-3 [nTPM]":"25.5","Cell RNA - SK-MEL-30 [nTPM]":"19.5","Cell RNA - SuSa [nTPM]":"26.1","Cell RNA - T-47d [nTPM]":"24.0","Cell RNA - THP-1 [nTPM]":"44.1","Cell RNA - TIME [nTPM]":"49.8","Cell RNA - U-138 MG [nTPM]":"15.5","Cell RNA - U-2 OS [nTPM]":"30.7","Cell RNA - U-2197 [nTPM]":"14.5","Cell RNA - U-251 MG [nTPM]":"30.5","Cell RNA - U-266\/70 [nTPM]":"24.8","Cell RNA - U-266\/84 [nTPM]":"20.9","Cell RNA - U-698 [nTPM]":"31.7","Cell RNA - U-87 MG [nTPM]":"17.1","Cell RNA - U-937 [nTPM]":"28.0","Cell RNA - WM-115 [nTPM]":"12.5","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.2","Blood RNA - eosinophil [nTPM]":"0.3","Blood RNA - gdT-cell [nTPM]":"0.2","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"1.5","Blood RNA - NK-cell [nTPM]":"0.5","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.2","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"14.0","Brain RNA - basal ganglia [nTPM]":"14.4","Brain RNA - cerebellum [nTPM]":"14.7","Brain RNA - cerebral cortex [nTPM]":"18.1","Brain RNA - hippocampal formation [nTPM]":"12.1","Brain RNA - hypothalamus [nTPM]":"9.1","Brain RNA - medulla oblongata [nTPM]":"9.3","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"8.6","Brain RNA - spinal cord [nTPM]":"3.1","Brain RNA - thalamus [nTPM]":"12.7","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"12.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.1","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"13.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"10.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.2","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"6.3","Single Cell Type RNA - Early spermatids [nTPM]":"2.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"16.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.0","Single Cell Type RNA - Fibroblasts [nTPM]":"8.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"24.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"13.1","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"23.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"13.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.8","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"15.7","Single Cell Type RNA - Langerhans cells [nTPM]":"18.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"15.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"15.0","Single Cell Type RNA - monocytes [nTPM]":"14.9","Single Cell Type RNA - Muller glia cells [nTPM]":"6.4","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.8","Single Cell Type RNA - Paneth cells [nTPM]":"9.5","Single Cell Type RNA - Peritubular cells [nTPM]":"10.9","Single Cell Type RNA - Plasma cells [nTPM]":"10.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"11.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"38.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.5","Single Cell Type RNA - Spermatogonia [nTPM]":"3.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - T-cells [nTPM]":"15.3","Single Cell Type RNA - Theca cells [nTPM]":"10.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.3","Single Cell Type RNA - Urothelial cells [nTPM]":"9.6"},{"Gene":"KRAS","Gene synonym":["KRAS1","KRAS2"],"Ensembl":"ENSG00000133703","Gene description":"KRAS proto-oncogene, GTPase","Uniprot":["P01116"],"Chromosome":"12","Position":"25205246-25250936","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Deafness","Disease variant","Ectodermal dysplasia","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049830"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"3300000","Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.86e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.74e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.42e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.75e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.8","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"11.0","Tissue RNA - appendix [nTPM]":"16.2","Tissue RNA - basal ganglia [nTPM]":"12.2","Tissue RNA - bone marrow [nTPM]":"27.8","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"9.5","Tissue RNA - choroid plexus [nTPM]":"4.6","Tissue RNA - colon [nTPM]":"22.0","Tissue RNA - duodenum [nTPM]":"14.0","Tissue RNA - endometrium 1 [nTPM]":"11.0","Tissue RNA - epididymis [nTPM]":"6.8","Tissue RNA - esophagus [nTPM]":"19.3","Tissue RNA - fallopian tube [nTPM]":"7.4","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"8.6","Tissue RNA - hippocampal formation [nTPM]":"12.5","Tissue RNA - hypothalamus [nTPM]":"12.0","Tissue RNA - kidney [nTPM]":"11.7","Tissue RNA - liver [nTPM]":"15.3","Tissue RNA - lung [nTPM]":"13.2","Tissue RNA - lymph node [nTPM]":"17.9","Tissue RNA - medulla oblongata [nTPM]":"8.5","Tissue RNA - midbrain [nTPM]":"9.7","Tissue RNA - ovary [nTPM]":"8.0","Tissue RNA - pancreas [nTPM]":"12.6","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"5.7","Tissue RNA - placenta [nTPM]":"17.0","Tissue RNA - pons [nTPM]":"8.7","Tissue RNA - prostate [nTPM]":"11.8","Tissue RNA - rectum [nTPM]":"23.0","Tissue RNA - retina [nTPM]":"22.7","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"8.3","Tissue RNA - skeletal muscle [nTPM]":"7.6","Tissue RNA - skin 1 [nTPM]":"13.6","Tissue RNA - small intestine [nTPM]":"19.5","Tissue RNA - smooth muscle [nTPM]":"13.6","Tissue RNA - spinal cord [nTPM]":"8.1","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"20.3","Tissue RNA - testis [nTPM]":"8.9","Tissue RNA - thalamus [nTPM]":"12.9","Tissue RNA - thymus [nTPM]":"17.2","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"10.3","Tissue RNA - tonsil [nTPM]":"17.4","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"11.4","Tissue RNA - white matter [nTPM]":"8.6","Cell RNA - A-431 [nTPM]":"15.9","Cell RNA - A549 [nTPM]":"14.3","Cell RNA - AF22 [nTPM]":"39.4","Cell RNA - AN3-CA [nTPM]":"20.7","Cell RNA - ASC diff [nTPM]":"14.1","Cell RNA - ASC TERT1 [nTPM]":"19.9","Cell RNA - BEWO [nTPM]":"68.9","Cell RNA - BJ [nTPM]":"17.3","Cell RNA - BJ hTERT+ [nTPM]":"22.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"18.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.9","Cell RNA - CACO-2 [nTPM]":"51.5","Cell RNA - CAPAN-2 [nTPM]":"30.7","Cell RNA - Daudi [nTPM]":"38.7","Cell RNA - EFO-21 [nTPM]":"10.4","Cell RNA - fHDF\/TERT166 [nTPM]":"32.0","Cell RNA - GAMG [nTPM]":"23.4","Cell RNA - HaCaT [nTPM]":"18.6","Cell RNA - HAP1 [nTPM]":"44.9","Cell RNA - HBEC3-KT [nTPM]":"17.3","Cell RNA - HBF TERT88 [nTPM]":"34.3","Cell RNA - HDLM-2 [nTPM]":"26.7","Cell RNA - HEK 293 [nTPM]":"15.0","Cell RNA - HEL [nTPM]":"37.6","Cell RNA - HeLa [nTPM]":"17.6","Cell RNA - Hep G2 [nTPM]":"15.6","Cell RNA - HHSteC [nTPM]":"15.8","Cell RNA - HL-60 [nTPM]":"32.8","Cell RNA - HMC-1 [nTPM]":"25.6","Cell RNA - HSkMC [nTPM]":"18.1","Cell RNA - hTCEpi [nTPM]":"25.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"21.9","Cell RNA - hTERT-HME1 [nTPM]":"20.2","Cell RNA - hTERT-RPE1 [nTPM]":"33.6","Cell RNA - HUVEC TERT2 [nTPM]":"27.1","Cell RNA - JURKAT [nTPM]":"28.7","Cell RNA - K-562 [nTPM]":"28.0","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"27.6","Cell RNA - MCF7 [nTPM]":"14.1","Cell RNA - MOLT-4 [nTPM]":"46.8","Cell RNA - NB-4 [nTPM]":"56.6","Cell RNA - NTERA-2 [nTPM]":"87.6","Cell RNA - OE19 [nTPM]":"25.3","Cell RNA - PC-3 [nTPM]":"7.4","Cell RNA - REH [nTPM]":"43.4","Cell RNA - RH-30 [nTPM]":"39.9","Cell RNA - RPMI-8226 [nTPM]":"59.9","Cell RNA - RPTEC TERT1 [nTPM]":"27.2","Cell RNA - RT4 [nTPM]":"22.4","Cell RNA - SCLC-21H [nTPM]":"11.2","Cell RNA - SH-SY5Y [nTPM]":"32.4","Cell RNA - SiHa [nTPM]":"20.5","Cell RNA - SK-BR-3 [nTPM]":"24.9","Cell RNA - SK-MEL-30 [nTPM]":"21.8","Cell RNA - SuSa [nTPM]":"97.4","Cell RNA - T-47d [nTPM]":"28.9","Cell RNA - THP-1 [nTPM]":"26.9","Cell RNA - TIME [nTPM]":"28.1","Cell RNA - U-138 MG [nTPM]":"18.7","Cell RNA - U-2 OS [nTPM]":"24.8","Cell RNA - U-2197 [nTPM]":"38.2","Cell RNA - U-251 MG [nTPM]":"22.0","Cell RNA - U-266\/70 [nTPM]":"16.4","Cell RNA - U-266\/84 [nTPM]":"28.5","Cell RNA - U-698 [nTPM]":"41.9","Cell RNA - U-87 MG [nTPM]":"15.4","Cell RNA - U-937 [nTPM]":"20.0","Cell RNA - WM-115 [nTPM]":"15.0","Blood RNA - basophil [nTPM]":"31.2","Blood RNA - classical monocyte [nTPM]":"8.1","Blood RNA - eosinophil [nTPM]":"13.7","Blood RNA - gdT-cell [nTPM]":"11.6","Blood RNA - intermediate monocyte [nTPM]":"16.4","Blood RNA - MAIT T-cell [nTPM]":"7.9","Blood RNA - memory B-cell [nTPM]":"10.7","Blood RNA - memory CD4 T-cell [nTPM]":"10.1","Blood RNA - memory CD8 T-cell [nTPM]":"13.1","Blood RNA - myeloid DC [nTPM]":"7.9","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"13.8","Blood RNA - naive CD8 T-cell [nTPM]":"12.4","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"11.2","Blood RNA - non-classical monocyte [nTPM]":"22.4","Blood RNA - plasmacytoid DC [nTPM]":"7.8","Blood RNA - T-reg [nTPM]":"7.6","Blood RNA - total PBMC [nTPM]":"5.8","Brain RNA - amygdala [nTPM]":"11.0","Brain RNA - basal ganglia [nTPM]":"12.2","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"12.5","Brain RNA - hypothalamus [nTPM]":"12.0","Brain RNA - medulla oblongata [nTPM]":"8.5","Brain RNA - midbrain [nTPM]":"9.7","Brain RNA - pons [nTPM]":"8.7","Brain RNA - spinal cord [nTPM]":"8.1","Brain RNA - thalamus [nTPM]":"12.9","Brain RNA - white matter [nTPM]":"8.6","Single Cell Type RNA - Adipocytes [nTPM]":"73.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.1","Single Cell Type RNA - Astrocytes [nTPM]":"16.6","Single Cell Type RNA - B-cells [nTPM]":"90.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"100.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"96.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"57.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"72.3","Single Cell Type RNA - Bipolar cells [nTPM]":"63.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"16.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"64.3","Single Cell Type RNA - Club cells [nTPM]":"53.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"38.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"94.2","Single Cell Type RNA - dendritic cells [nTPM]":"66.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"161.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"58.7","Single Cell Type RNA - Ductal cells [nTPM]":"77.5","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"40.8","Single Cell Type RNA - Endothelial cells [nTPM]":"77.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"78.8","Single Cell Type RNA - Erythroid cells [nTPM]":"60.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"91.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.4","Single Cell Type RNA - Fibroblasts [nTPM]":"50.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"98.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"53.4","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"26.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"77.8","Single Cell Type RNA - Hepatocytes [nTPM]":"56.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.5","Single Cell Type RNA - Horizontal cells [nTPM]":"92.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"45.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"92.9","Single Cell Type RNA - Ionocytes [nTPM]":"36.7","Single Cell Type RNA - Kupffer cells [nTPM]":"53.9","Single Cell Type RNA - Langerhans cells [nTPM]":"83.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"40.7","Single Cell Type RNA - Macrophages [nTPM]":"75.3","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"28.1","Single Cell Type RNA - monocytes [nTPM]":"82.9","Single Cell Type RNA - Muller glia cells [nTPM]":"41.7","Single Cell Type RNA - NK-cells [nTPM]":"49.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"114.2","Single Cell Type RNA - Paneth cells [nTPM]":"104.7","Single Cell Type RNA - Peritubular cells [nTPM]":"51.6","Single Cell Type RNA - Plasma cells [nTPM]":"85.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"130.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"63.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"52.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"42.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"65.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.2","Single Cell Type RNA - Spermatocytes [nTPM]":"53.0","Single Cell Type RNA - Spermatogonia [nTPM]":"40.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"93.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"155.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"139.1","Single Cell Type RNA - T-cells [nTPM]":"83.0","Single Cell Type RNA - Theca cells [nTPM]":"36.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"96.7","Single Cell Type RNA - Urothelial cells [nTPM]":"176.9"},{"Gene":"LMO2","Gene synonym":["RBTN2","RBTNL1","RHOM2","TTG2"],"Ensembl":"ENSG00000135363","Gene description":"LIM domain only 2","Uniprot":["P25791"],"Chromosome":"11","Position":"33858576-33892076","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"109.2","Endothelial cells":"144.6","Erythroid cells":"103.7","Hepatic stellate cells":"167.4","Kupffer cells":"65.0","Microglial cells":"64.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"30.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"1.9","granulocytes":"1.5","monocytes":"1.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"71.8","HL-60":"72.7","K-562":"60.9","NB-4":"27.3","THP-1":"81.6","U-937":"29.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016258","HPA029285","HPA070901","HPA070910"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 32: U-937 - Innate immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB016258":"AB_2136572","HPA029285":"AB_2672978","HPA070901":null,"HPA070910":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.12e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.95e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.86e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.65e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.0","Tissue RNA - adrenal gland [nTPM]":"5.9","Tissue RNA - amygdala [nTPM]":"14.9","Tissue RNA - appendix [nTPM]":"11.4","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"27.7","Tissue RNA - breast [nTPM]":"12.5","Tissue RNA - cerebellum [nTPM]":"14.2","Tissue RNA - cerebral cortex [nTPM]":"16.6","Tissue RNA - cervix [nTPM]":"8.4","Tissue RNA - choroid plexus [nTPM]":"13.4","Tissue RNA - colon [nTPM]":"5.0","Tissue RNA - duodenum [nTPM]":"4.6","Tissue RNA - endometrium 1 [nTPM]":"6.5","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"6.8","Tissue RNA - fallopian tube [nTPM]":"8.3","Tissue RNA - gallbladder [nTPM]":"5.4","Tissue RNA - heart muscle [nTPM]":"4.4","Tissue RNA - hippocampal formation [nTPM]":"14.7","Tissue RNA - hypothalamus [nTPM]":"16.0","Tissue RNA - kidney [nTPM]":"13.1","Tissue RNA - liver [nTPM]":"2.3","Tissue RNA - lung [nTPM]":"18.2","Tissue RNA - lymph node [nTPM]":"19.4","Tissue RNA - medulla oblongata [nTPM]":"19.9","Tissue RNA - midbrain [nTPM]":"16.3","Tissue RNA - ovary [nTPM]":"3.5","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"2.3","Tissue RNA - pituitary gland [nTPM]":"8.6","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"1.5","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"5.3","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"23.4","Tissue RNA - skin 1 [nTPM]":"4.9","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"4.8","Tissue RNA - spinal cord [nTPM]":"18.7","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"1.7","Tissue RNA - thalamus [nTPM]":"19.0","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"12.3","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"8.4","Tissue RNA - urinary bladder [nTPM]":"5.8","Tissue RNA - vagina [nTPM]":"7.3","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"2.2","Cell RNA - Daudi [nTPM]":"1.3","Cell RNA - EFO-21 [nTPM]":"12.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.7","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.4","Cell RNA - HEL [nTPM]":"71.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"72.7","Cell RNA - HMC-1 [nTPM]":"18.5","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"10.2","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"60.9","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"5.1","Cell RNA - NB-4 [nTPM]":"27.3","Cell RNA - NTERA-2 [nTPM]":"0.9","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"15.3","Cell RNA - RH-30 [nTPM]":"0.8","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.8","Cell RNA - SCLC-21H [nTPM]":"4.3","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"81.6","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"1.7","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"4.7","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"0.3","Blood RNA - basophil [nTPM]":"0.6","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.5","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.7","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"14.9","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"14.2","Brain RNA - cerebral cortex [nTPM]":"16.6","Brain RNA - hippocampal formation [nTPM]":"14.7","Brain RNA - hypothalamus [nTPM]":"16.0","Brain RNA - medulla oblongata [nTPM]":"19.9","Brain RNA - midbrain [nTPM]":"16.3","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"18.7","Brain RNA - thalamus [nTPM]":"19.0","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"109.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.1","Single Cell Type RNA - Astrocytes [nTPM]":"8.5","Single Cell Type RNA - B-cells [nTPM]":"6.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"1.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"3.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"144.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"103.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"9.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"39.6","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"0.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"167.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"39.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"65.0","Single Cell Type RNA - Langerhans cells [nTPM]":"56.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"54.1","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"64.6","Single Cell Type RNA - monocytes [nTPM]":"47.5","Single Cell Type RNA - Muller glia cells [nTPM]":"1.1","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"3.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"7.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.5","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"12.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.5","Single Cell Type RNA - Urothelial cells [nTPM]":"25.1"},{"Gene":"LRP6","Gene synonym":["ADCAD2"],"Ensembl":"ENSG00000070018","Gene description":"LDL receptor related protein 6","Uniprot":["O75581"],"Chromosome":"12","Position":"12116025-12267044","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Endocytosis","Wnt signaling pathway"],"Molecular function":["Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"96.6","Oligodendrocyte precursor cells":"108.0","Oligodendrocytes":"97.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004490","HPA029925"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"390000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004490":"AB_627894","HPA029925":"AB_10601768"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.47e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.7","Tissue RNA - adrenal gland [nTPM]":"2.2","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"1.2","Tissue RNA - basal ganglia [nTPM]":"3.9","Tissue RNA - bone marrow [nTPM]":"0.2","Tissue RNA - breast [nTPM]":"4.5","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"6.6","Tissue RNA - choroid plexus [nTPM]":"13.5","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"6.5","Tissue RNA - epididymis [nTPM]":"1.9","Tissue RNA - esophagus [nTPM]":"2.0","Tissue RNA - fallopian tube [nTPM]":"4.4","Tissue RNA - gallbladder [nTPM]":"2.8","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"2.0","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"7.9","Tissue RNA - lung [nTPM]":"4.6","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"2.2","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"5.4","Tissue RNA - pancreas [nTPM]":"4.9","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"8.3","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"2.8","Tissue RNA - retina [nTPM]":"2.8","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"3.2","Tissue RNA - skeletal muscle [nTPM]":"4.5","Tissue RNA - skin 1 [nTPM]":"3.4","Tissue RNA - small intestine [nTPM]":"2.7","Tissue RNA - smooth muscle [nTPM]":"4.1","Tissue RNA - spinal cord [nTPM]":"1.8","Tissue RNA - spleen [nTPM]":"0.9","Tissue RNA - stomach 1 [nTPM]":"3.4","Tissue RNA - testis [nTPM]":"2.1","Tissue RNA - thalamus [nTPM]":"2.8","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"4.5","Tissue RNA - tongue [nTPM]":"4.6","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"3.4","Tissue RNA - vagina [nTPM]":"5.3","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"3.9","Cell RNA - A549 [nTPM]":"13.3","Cell RNA - AF22 [nTPM]":"9.9","Cell RNA - AN3-CA [nTPM]":"5.3","Cell RNA - ASC diff [nTPM]":"6.1","Cell RNA - ASC TERT1 [nTPM]":"4.0","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"5.8","Cell RNA - BJ hTERT+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.3","Cell RNA - CACO-2 [nTPM]":"6.5","Cell RNA - CAPAN-2 [nTPM]":"3.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"2.8","Cell RNA - fHDF\/TERT166 [nTPM]":"5.6","Cell RNA - GAMG [nTPM]":"3.8","Cell RNA - HaCaT [nTPM]":"3.7","Cell RNA - HAP1 [nTPM]":"14.6","Cell RNA - HBEC3-KT [nTPM]":"3.7","Cell RNA - HBF TERT88 [nTPM]":"8.7","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"3.9","Cell RNA - HEL [nTPM]":"4.1","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"3.2","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"5.7","Cell RNA - HMC-1 [nTPM]":"2.8","Cell RNA - HSkMC [nTPM]":"3.2","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"6.9","Cell RNA - hTERT-HME1 [nTPM]":"5.4","Cell RNA - hTERT-RPE1 [nTPM]":"5.1","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"5.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.0","Cell RNA - MCF7 [nTPM]":"3.2","Cell RNA - MOLT-4 [nTPM]":"4.2","Cell RNA - NB-4 [nTPM]":"1.1","Cell RNA - NTERA-2 [nTPM]":"14.4","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"5.3","Cell RNA - RH-30 [nTPM]":"9.2","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.8","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"7.4","Cell RNA - SK-BR-3 [nTPM]":"2.5","Cell RNA - SK-MEL-30 [nTPM]":"6.0","Cell RNA - SuSa [nTPM]":"11.5","Cell RNA - T-47d [nTPM]":"2.0","Cell RNA - THP-1 [nTPM]":"3.7","Cell RNA - TIME [nTPM]":"6.9","Cell RNA - U-138 MG [nTPM]":"3.6","Cell RNA - U-2 OS [nTPM]":"13.2","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"4.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"1.9","Cell RNA - U-87 MG [nTPM]":"2.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"6.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"3.9","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"2.0","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"2.2","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"1.8","Brain RNA - thalamus [nTPM]":"2.8","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"21.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"41.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"49.5","Single Cell Type RNA - Astrocytes [nTPM]":"96.6","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"28.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"19.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"16.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"22.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.0","Single Cell Type RNA - Endothelial cells [nTPM]":"25.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"10.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"58.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.2","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"29.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"32.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"46.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.3","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.0","Single Cell Type RNA - Late spermatids [nTPM]":"5.1","Single Cell Type RNA - Leydig cells [nTPM]":"30.4","Single Cell Type RNA - Macrophages [nTPM]":"1.7","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"35.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"19.9","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"108.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"97.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.3","Single Cell Type RNA - Paneth cells [nTPM]":"20.5","Single Cell Type RNA - Peritubular cells [nTPM]":"38.7","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"14.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"29.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"17.3","Single Cell Type RNA - Spermatocytes [nTPM]":"21.5","Single Cell Type RNA - Spermatogonia [nTPM]":"26.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"23.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.1"},{"Gene":"LYL1","Gene synonym":["bHLHa18"],"Ensembl":"ENSG00000104903","Gene description":"LYL1 basic helix-loop-helix family member","Uniprot":["P12980"],"Chromosome":"19","Position":"13099033-13103161","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"35.9","lymphoid tissue":"36.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"335.4","Erythroid cells":"298.9","Late spermatids":"763.9","Spermatocytes":"120.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"6.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"3.7","granulocytes":"6.4","monocytes":"2.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"127.7","HL-60":"90.5","HMC-1":"206.6","K-562":"102.1","NB-4":"131.9","REH":"96.5","THP-1":"86.1","U-937":"86.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA072177"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA072177":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.89e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.28e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.7","Tissue RNA - adrenal gland [nTPM]":"4.1","Tissue RNA - amygdala [nTPM]":"6.3","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"6.0","Tissue RNA - bone marrow [nTPM]":"35.9","Tissue RNA - breast [nTPM]":"7.3","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"6.7","Tissue RNA - choroid plexus [nTPM]":"4.9","Tissue RNA - colon [nTPM]":"6.4","Tissue RNA - duodenum [nTPM]":"2.0","Tissue RNA - endometrium 1 [nTPM]":"7.7","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"3.2","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"6.4","Tissue RNA - hypothalamus [nTPM]":"6.4","Tissue RNA - kidney [nTPM]":"5.7","Tissue RNA - liver [nTPM]":"2.6","Tissue RNA - lung [nTPM]":"12.3","Tissue RNA - lymph node [nTPM]":"12.3","Tissue RNA - medulla oblongata [nTPM]":"8.9","Tissue RNA - midbrain [nTPM]":"6.8","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"2.0","Tissue RNA - parathyroid gland [nTPM]":"0.5","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"5.6","Tissue RNA - pons [nTPM]":"8.1","Tissue RNA - prostate [nTPM]":"5.7","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"3.7","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"14.1","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"9.1","Tissue RNA - spleen [nTPM]":"36.7","Tissue RNA - stomach 1 [nTPM]":"4.1","Tissue RNA - testis [nTPM]":"20.8","Tissue RNA - thalamus [nTPM]":"9.0","Tissue RNA - thymus [nTPM]":"2.3","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"1.9","Tissue RNA - tonsil [nTPM]":"6.2","Tissue RNA - urinary bladder [nTPM]":"7.8","Tissue RNA - vagina [nTPM]":"5.6","Tissue RNA - white matter [nTPM]":"9.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.4","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"24.8","Cell RNA - EFO-21 [nTPM]":"8.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.4","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"14.7","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"127.7","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"1.4","Cell RNA - HL-60 [nTPM]":"90.5","Cell RNA - HMC-1 [nTPM]":"206.6","Cell RNA - HSkMC [nTPM]":"0.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"31.9","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"102.1","Cell RNA - Karpas-707 [nTPM]":"4.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.5","Cell RNA - NB-4 [nTPM]":"131.9","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.4","Cell RNA - PC-3 [nTPM]":"3.2","Cell RNA - REH [nTPM]":"96.5","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"11.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"9.1","Cell RNA - SiHa [nTPM]":"2.8","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"6.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"86.1","Cell RNA - TIME [nTPM]":"51.8","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"3.6","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"20.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"86.1","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"1.4","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"2.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.2","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"3.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"2.8","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"6.3","Brain RNA - basal ganglia [nTPM]":"6.0","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.4","Brain RNA - hypothalamus [nTPM]":"6.4","Brain RNA - medulla oblongata [nTPM]":"8.9","Brain RNA - midbrain [nTPM]":"6.8","Brain RNA - pons [nTPM]":"8.1","Brain RNA - spinal cord [nTPM]":"9.1","Brain RNA - thalamus [nTPM]":"9.0","Brain RNA - white matter [nTPM]":"9.6","Single Cell Type RNA - Adipocytes [nTPM]":"33.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"80.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"6.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.4","Single Cell Type RNA - Early spermatids [nTPM]":"335.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.9","Single Cell Type RNA - Endothelial cells [nTPM]":"40.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"298.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.3","Single Cell Type RNA - Fibroblasts [nTPM]":"3.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"45.1","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.9","Single Cell Type RNA - Hepatocytes [nTPM]":"1.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"113.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"60.3","Single Cell Type RNA - Langerhans cells [nTPM]":"35.1","Single Cell Type RNA - Late spermatids [nTPM]":"763.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"68.3","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"13.1","Single Cell Type RNA - monocytes [nTPM]":"36.4","Single Cell Type RNA - Muller glia cells [nTPM]":"1.5","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.0","Single Cell Type RNA - Paneth cells [nTPM]":"1.6","Single Cell Type RNA - Peritubular cells [nTPM]":"12.0","Single Cell Type RNA - Plasma cells [nTPM]":"6.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.2","Single Cell Type RNA - Spermatocytes [nTPM]":"120.6","Single Cell Type RNA - Spermatogonia [nTPM]":"5.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - T-cells [nTPM]":"9.0","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"MAF","Gene synonym":["c-MAF"],"Ensembl":"ENSG00000178573","Gene description":"MAF bZIP transcription factor","Uniprot":["O75444"],"Chromosome":"16","Position":"79585843-79600737","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Cataract","Deafness","Disease variant","Dwarfism","Mental retardation","Proto-oncogene","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatic stellate cells":"407.6","Hofbauer cells":"273.6","Inhibitory neurons":"378.7","Kupffer cells":"394.7","Proximal enterocytes":"288.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"38.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"38.1"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"Karpas-707":"207.0","RPMI-8226":"355.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010296","HPA028289"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 41: Intestine & Liver - Lipid metabolism","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 24: Non-specific - Transcription regulation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB010296":"AB_638562","HPA028289":"AB_10602024"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.76e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.65e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.76e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.74e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"27.8","Tissue RNA - adrenal gland [nTPM]":"15.4","Tissue RNA - amygdala [nTPM]":"14.6","Tissue RNA - appendix [nTPM]":"20.7","Tissue RNA - basal ganglia [nTPM]":"14.5","Tissue RNA - bone marrow [nTPM]":"4.0","Tissue RNA - breast [nTPM]":"17.3","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"13.5","Tissue RNA - cervix [nTPM]":"35.0","Tissue RNA - choroid plexus [nTPM]":"14.2","Tissue RNA - colon [nTPM]":"11.4","Tissue RNA - duodenum [nTPM]":"70.3","Tissue RNA - endometrium 1 [nTPM]":"23.5","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"22.6","Tissue RNA - fallopian tube [nTPM]":"20.1","Tissue RNA - gallbladder [nTPM]":"16.7","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"13.7","Tissue RNA - hypothalamus [nTPM]":"13.0","Tissue RNA - kidney [nTPM]":"48.2","Tissue RNA - liver [nTPM]":"25.7","Tissue RNA - lung [nTPM]":"18.8","Tissue RNA - lymph node [nTPM]":"30.9","Tissue RNA - medulla oblongata [nTPM]":"19.0","Tissue RNA - midbrain [nTPM]":"22.6","Tissue RNA - ovary [nTPM]":"39.2","Tissue RNA - pancreas [nTPM]":"3.2","Tissue RNA - parathyroid gland [nTPM]":"50.8","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"36.1","Tissue RNA - pons [nTPM]":"17.6","Tissue RNA - prostate [nTPM]":"18.4","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"11.8","Tissue RNA - seminal vesicle [nTPM]":"15.4","Tissue RNA - skeletal muscle [nTPM]":"49.6","Tissue RNA - skin 1 [nTPM]":"57.8","Tissue RNA - small intestine [nTPM]":"83.0","Tissue RNA - smooth muscle [nTPM]":"17.8","Tissue RNA - spinal cord [nTPM]":"18.7","Tissue RNA - spleen [nTPM]":"26.0","Tissue RNA - stomach 1 [nTPM]":"13.0","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"28.7","Tissue RNA - thymus [nTPM]":"17.9","Tissue RNA - thyroid gland [nTPM]":"23.1","Tissue RNA - tongue [nTPM]":"19.8","Tissue RNA - tonsil [nTPM]":"23.9","Tissue RNA - urinary bladder [nTPM]":"17.7","Tissue RNA - vagina [nTPM]":"30.5","Tissue RNA - white matter [nTPM]":"29.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"22.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.8","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"2.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.8","Cell RNA - HAP1 [nTPM]":"0.7","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"7.2","Cell RNA - HEK 293 [nTPM]":"8.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"1.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"14.3","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"6.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"2.4","Cell RNA - Karpas-707 [nTPM]":"207.0","Cell RNA - LHCN-M2 [nTPM]":"1.5","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"13.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"6.2","Cell RNA - RPMI-8226 [nTPM]":"355.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"1.9","Cell RNA - SCLC-21H [nTPM]":"0.5","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.9","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"8.7","Cell RNA - T-47d [nTPM]":"0.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"4.5","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"6.9","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.9","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1.4","Blood RNA - basophil [nTPM]":"38.1","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"1.1","Blood RNA - intermediate monocyte [nTPM]":"1.1","Blood RNA - MAIT T-cell [nTPM]":"8.6","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"3.2","Blood RNA - memory CD8 T-cell [nTPM]":"2.7","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"4.7","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"14.6","Brain RNA - basal ganglia [nTPM]":"14.5","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"13.5","Brain RNA - hippocampal formation [nTPM]":"13.7","Brain RNA - hypothalamus [nTPM]":"13.0","Brain RNA - medulla oblongata [nTPM]":"19.0","Brain RNA - midbrain [nTPM]":"22.6","Brain RNA - pons [nTPM]":"17.6","Brain RNA - spinal cord [nTPM]":"18.7","Brain RNA - thalamus [nTPM]":"28.7","Brain RNA - white matter [nTPM]":"29.8","Single Cell Type RNA - Adipocytes [nTPM]":"40.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"14.6","Single Cell Type RNA - Astrocytes [nTPM]":"24.8","Single Cell Type RNA - B-cells [nTPM]":"10.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"88.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"9.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"8.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"7.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.7","Single Cell Type RNA - dendritic cells [nTPM]":"71.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"1.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.1","Single Cell Type RNA - Endothelial cells [nTPM]":"42.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.0","Single Cell Type RNA - Erythroid cells [nTPM]":"8.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.0","Single Cell Type RNA - Fibroblasts [nTPM]":"73.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"6.6","Single Cell Type RNA - granulocytes [nTPM]":"22.1","Single Cell Type RNA - Granulosa cells [nTPM]":"73.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"407.6","Single Cell Type RNA - Hepatocytes [nTPM]":"63.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"273.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"378.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.9","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"394.7","Single Cell Type RNA - Langerhans cells [nTPM]":"57.9","Single Cell Type RNA - Late spermatids [nTPM]":"9.0","Single Cell Type RNA - Leydig cells [nTPM]":"149.8","Single Cell Type RNA - Macrophages [nTPM]":"127.2","Single Cell Type RNA - Melanocytes [nTPM]":"44.4","Single Cell Type RNA - Microglial cells [nTPM]":"122.7","Single Cell Type RNA - monocytes [nTPM]":"2.7","Single Cell Type RNA - Muller glia cells [nTPM]":"78.1","Single Cell Type RNA - NK-cells [nTPM]":"40.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"67.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.0","Single Cell Type RNA - Paneth cells [nTPM]":"9.9","Single Cell Type RNA - Peritubular cells [nTPM]":"115.1","Single Cell Type RNA - Plasma cells [nTPM]":"48.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"288.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"146.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"42.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"107.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"141.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"122.2","Single Cell Type RNA - Theca cells [nTPM]":"28.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.1","Single Cell Type RNA - Urothelial cells [nTPM]":"5.4"},{"Gene":"MAML2","Gene synonym":["KIAA1819","MAM3"],"Ensembl":"ENSG00000184384","Gene description":"Mastermind like transcriptional coactivator 2","Uniprot":["Q8IZL2"],"Chromosome":"11","Position":"95976598-96343195","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"690.5","Microglial cells":"579.9","Oligodendrocyte precursor cells":"1300.8","Oligodendrocytes":"311.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HDLM-2":"52.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA035223"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: NK-cells - Unknown function","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 44: HDLM-2 - Immune response","Single cell expression cluster":"Cluster 68: Oligodendrocytes - Mixed function","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"HPA035223":"AB_10671101"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.11e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.32e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.66e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.89e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.11e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.90e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.99e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.9","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"5.8","Tissue RNA - appendix [nTPM]":"6.3","Tissue RNA - basal ganglia [nTPM]":"5.5","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"14.2","Tissue RNA - cerebellum [nTPM]":"17.2","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"10.6","Tissue RNA - choroid plexus [nTPM]":"6.9","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"3.0","Tissue RNA - endometrium 1 [nTPM]":"5.4","Tissue RNA - epididymis [nTPM]":"1.8","Tissue RNA - esophagus [nTPM]":"5.5","Tissue RNA - fallopian tube [nTPM]":"8.0","Tissue RNA - gallbladder [nTPM]":"7.7","Tissue RNA - heart muscle [nTPM]":"4.4","Tissue RNA - hippocampal formation [nTPM]":"7.1","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"9.9","Tissue RNA - liver [nTPM]":"2.4","Tissue RNA - lung [nTPM]":"9.8","Tissue RNA - lymph node [nTPM]":"8.7","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"9.0","Tissue RNA - ovary [nTPM]":"7.9","Tissue RNA - pancreas [nTPM]":"5.9","Tissue RNA - parathyroid gland [nTPM]":"5.9","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"12.2","Tissue RNA - pons [nTPM]":"7.4","Tissue RNA - prostate [nTPM]":"7.4","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"6.8","Tissue RNA - salivary gland [nTPM]":"11.0","Tissue RNA - seminal vesicle [nTPM]":"5.7","Tissue RNA - skeletal muscle [nTPM]":"2.0","Tissue RNA - skin 1 [nTPM]":"7.9","Tissue RNA - small intestine [nTPM]":"4.8","Tissue RNA - smooth muscle [nTPM]":"6.5","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"10.3","Tissue RNA - stomach 1 [nTPM]":"4.8","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"7.5","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"6.5","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"6.5","Tissue RNA - white matter [nTPM]":"6.6","Cell RNA - A-431 [nTPM]":"10.7","Cell RNA - A549 [nTPM]":"2.0","Cell RNA - AF22 [nTPM]":"17.8","Cell RNA - AN3-CA [nTPM]":"4.7","Cell RNA - ASC diff [nTPM]":"18.1","Cell RNA - ASC TERT1 [nTPM]":"20.7","Cell RNA - BEWO [nTPM]":"3.8","Cell RNA - BJ [nTPM]":"12.1","Cell RNA - BJ hTERT+ [nTPM]":"17.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.1","Cell RNA - CACO-2 [nTPM]":"1.3","Cell RNA - CAPAN-2 [nTPM]":"22.1","Cell RNA - Daudi [nTPM]":"2.3","Cell RNA - EFO-21 [nTPM]":"27.7","Cell RNA - fHDF\/TERT166 [nTPM]":"28.1","Cell RNA - GAMG [nTPM]":"4.1","Cell RNA - HaCaT [nTPM]":"9.6","Cell RNA - HAP1 [nTPM]":"3.6","Cell RNA - HBEC3-KT [nTPM]":"11.7","Cell RNA - HBF TERT88 [nTPM]":"10.7","Cell RNA - HDLM-2 [nTPM]":"52.8","Cell RNA - HEK 293 [nTPM]":"1.3","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"3.7","Cell RNA - Hep G2 [nTPM]":"4.1","Cell RNA - HHSteC [nTPM]":"10.5","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"30.4","Cell RNA - hTCEpi [nTPM]":"1.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.9","Cell RNA - hTERT-HME1 [nTPM]":"8.2","Cell RNA - hTERT-RPE1 [nTPM]":"14.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.5","Cell RNA - JURKAT [nTPM]":"0.3","Cell RNA - K-562 [nTPM]":"6.1","Cell RNA - Karpas-707 [nTPM]":"3.2","Cell RNA - LHCN-M2 [nTPM]":"14.0","Cell RNA - MCF7 [nTPM]":"0.9","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"2.9","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"5.5","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"3.7","Cell RNA - RH-30 [nTPM]":"3.4","Cell RNA - RPMI-8226 [nTPM]":"12.3","Cell RNA - RPTEC TERT1 [nTPM]":"11.6","Cell RNA - RT4 [nTPM]":"14.8","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.6","Cell RNA - SiHa [nTPM]":"4.5","Cell RNA - SK-BR-3 [nTPM]":"1.9","Cell RNA - SK-MEL-30 [nTPM]":"5.0","Cell RNA - SuSa [nTPM]":"5.7","Cell RNA - T-47d [nTPM]":"1.7","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"19.7","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"4.7","Cell RNA - U-251 MG [nTPM]":"7.7","Cell RNA - U-266\/70 [nTPM]":"2.2","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"3.3","Cell RNA - U-87 MG [nTPM]":"6.5","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"25.6","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.8","Blood RNA - intermediate monocyte [nTPM]":"0.3","Blood RNA - MAIT T-cell [nTPM]":"1.3","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"2.1","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.2","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"2.4","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"5.8","Brain RNA - basal ganglia [nTPM]":"5.5","Brain RNA - cerebellum [nTPM]":"17.2","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"7.1","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"9.0","Brain RNA - pons [nTPM]":"7.4","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"7.5","Brain RNA - white matter [nTPM]":"6.6","Single Cell Type RNA - Adipocytes [nTPM]":"43.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"690.5","Single Cell Type RNA - B-cells [nTPM]":"35.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"19.9","Single Cell Type RNA - Bipolar cells [nTPM]":"44.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"28.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"16.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.4","Single Cell Type RNA - dendritic cells [nTPM]":"21.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"31.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"61.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"49.4","Single Cell Type RNA - Endothelial cells [nTPM]":"24.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.7","Single Cell Type RNA - Erythroid cells [nTPM]":"2.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"81.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.0","Single Cell Type RNA - Fibroblasts [nTPM]":"41.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"52.3","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"44.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"36.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.6","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"19.2","Single Cell Type RNA - Langerhans cells [nTPM]":"21.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.0","Single Cell Type RNA - Leydig cells [nTPM]":"8.7","Single Cell Type RNA - Macrophages [nTPM]":"29.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"579.9","Single Cell Type RNA - monocytes [nTPM]":"26.0","Single Cell Type RNA - Muller glia cells [nTPM]":"21.9","Single Cell Type RNA - NK-cells [nTPM]":"16.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1300.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"311.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.0","Single Cell Type RNA - Paneth cells [nTPM]":"16.8","Single Cell Type RNA - Peritubular cells [nTPM]":"8.6","Single Cell Type RNA - Plasma cells [nTPM]":"18.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"19.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"24.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"25.9","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.0","Single Cell Type RNA - T-cells [nTPM]":"38.1","Single Cell Type RNA - Theca cells [nTPM]":"9.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.3","Single Cell Type RNA - Urothelial cells [nTPM]":"19.2"},{"Gene":"MAP2K1","Gene synonym":["MAPKK1","MEK1","PRKMK1"],"Ensembl":"ENSG00000169032","Gene description":"Mitogen-activated protein kinase kinase 1","Uniprot":["Q02750"],"Chromosome":"15","Position":"66386837-66491544","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Disease variant","Ectodermal dysplasia","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Hepatocytes":"172.5","Langerhans cells":"265.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003834","HPA026430"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"120000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 18: U-2197 - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003834":"AB_562310","HPA026430":"AB_1853742"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.95e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.62e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.40e-3"},"Tissue RNA - adipose tissue [nTPM]":"57.9","Tissue RNA - adrenal gland [nTPM]":"31.0","Tissue RNA - amygdala [nTPM]":"47.6","Tissue RNA - appendix [nTPM]":"38.3","Tissue RNA - basal ganglia [nTPM]":"79.7","Tissue RNA - bone marrow [nTPM]":"63.7","Tissue RNA - breast [nTPM]":"32.5","Tissue RNA - cerebellum [nTPM]":"30.2","Tissue RNA - cerebral cortex [nTPM]":"61.3","Tissue RNA - cervix [nTPM]":"31.1","Tissue RNA - choroid plexus [nTPM]":"22.5","Tissue RNA - colon [nTPM]":"26.5","Tissue RNA - duodenum [nTPM]":"19.4","Tissue RNA - endometrium 1 [nTPM]":"26.3","Tissue RNA - epididymis [nTPM]":"29.6","Tissue RNA - esophagus [nTPM]":"51.8","Tissue RNA - fallopian tube [nTPM]":"23.7","Tissue RNA - gallbladder [nTPM]":"27.0","Tissue RNA - heart muscle [nTPM]":"40.7","Tissue RNA - hippocampal formation [nTPM]":"69.4","Tissue RNA - hypothalamus [nTPM]":"44.3","Tissue RNA - kidney [nTPM]":"31.2","Tissue RNA - liver [nTPM]":"105.3","Tissue RNA - lung [nTPM]":"34.7","Tissue RNA - lymph node [nTPM]":"49.5","Tissue RNA - medulla oblongata [nTPM]":"31.6","Tissue RNA - midbrain [nTPM]":"32.6","Tissue RNA - ovary [nTPM]":"25.7","Tissue RNA - pancreas [nTPM]":"22.4","Tissue RNA - parathyroid gland [nTPM]":"38.5","Tissue RNA - pituitary gland [nTPM]":"26.8","Tissue RNA - placenta [nTPM]":"29.6","Tissue RNA - pons [nTPM]":"40.1","Tissue RNA - prostate [nTPM]":"26.2","Tissue RNA - rectum [nTPM]":"23.6","Tissue RNA - retina [nTPM]":"34.1","Tissue RNA - salivary gland [nTPM]":"29.3","Tissue RNA - seminal vesicle [nTPM]":"21.8","Tissue RNA - skeletal muscle [nTPM]":"85.5","Tissue RNA - skin 1 [nTPM]":"23.7","Tissue RNA - small intestine [nTPM]":"27.0","Tissue RNA - smooth muscle [nTPM]":"31.9","Tissue RNA - spinal cord [nTPM]":"35.7","Tissue RNA - spleen [nTPM]":"32.6","Tissue RNA - stomach 1 [nTPM]":"24.1","Tissue RNA - testis [nTPM]":"15.2","Tissue RNA - thalamus [nTPM]":"42.8","Tissue RNA - thymus [nTPM]":"33.8","Tissue RNA - thyroid gland [nTPM]":"22.8","Tissue RNA - tongue [nTPM]":"51.3","Tissue RNA - tonsil [nTPM]":"55.4","Tissue RNA - urinary bladder [nTPM]":"31.2","Tissue RNA - vagina [nTPM]":"33.7","Tissue RNA - white matter [nTPM]":"49.9","Cell RNA - A-431 [nTPM]":"105.8","Cell RNA - A549 [nTPM]":"55.3","Cell RNA - AF22 [nTPM]":"94.4","Cell RNA - AN3-CA [nTPM]":"39.0","Cell RNA - ASC diff [nTPM]":"55.3","Cell RNA - ASC TERT1 [nTPM]":"41.3","Cell RNA - BEWO [nTPM]":"53.8","Cell RNA - BJ [nTPM]":"83.6","Cell RNA - BJ hTERT+ [nTPM]":"61.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"76.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"68.1","Cell RNA - CACO-2 [nTPM]":"79.0","Cell RNA - CAPAN-2 [nTPM]":"82.1","Cell RNA - Daudi [nTPM]":"96.8","Cell RNA - EFO-21 [nTPM]":"93.2","Cell RNA - fHDF\/TERT166 [nTPM]":"59.9","Cell RNA - GAMG [nTPM]":"58.2","Cell RNA - HaCaT [nTPM]":"93.3","Cell RNA - HAP1 [nTPM]":"88.8","Cell RNA - HBEC3-KT [nTPM]":"106.4","Cell RNA - HBF TERT88 [nTPM]":"89.8","Cell RNA - HDLM-2 [nTPM]":"79.1","Cell RNA - HEK 293 [nTPM]":"56.8","Cell RNA - HEL [nTPM]":"30.9","Cell RNA - HeLa [nTPM]":"50.4","Cell RNA - Hep G2 [nTPM]":"40.7","Cell RNA - HHSteC [nTPM]":"45.1","Cell RNA - HL-60 [nTPM]":"41.0","Cell RNA - HMC-1 [nTPM]":"45.3","Cell RNA - HSkMC [nTPM]":"32.3","Cell RNA - hTCEpi [nTPM]":"64.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.9","Cell RNA - hTERT-HME1 [nTPM]":"81.6","Cell RNA - hTERT-RPE1 [nTPM]":"81.5","Cell RNA - HUVEC TERT2 [nTPM]":"60.7","Cell RNA - JURKAT [nTPM]":"48.0","Cell RNA - K-562 [nTPM]":"54.3","Cell RNA - Karpas-707 [nTPM]":"116.7","Cell RNA - LHCN-M2 [nTPM]":"113.4","Cell RNA - MCF7 [nTPM]":"40.3","Cell RNA - MOLT-4 [nTPM]":"33.5","Cell RNA - NB-4 [nTPM]":"51.9","Cell RNA - NTERA-2 [nTPM]":"47.9","Cell RNA - OE19 [nTPM]":"93.9","Cell RNA - PC-3 [nTPM]":"42.9","Cell RNA - REH [nTPM]":"39.2","Cell RNA - RH-30 [nTPM]":"58.1","Cell RNA - RPMI-8226 [nTPM]":"84.7","Cell RNA - RPTEC TERT1 [nTPM]":"74.8","Cell RNA - RT4 [nTPM]":"48.5","Cell RNA - SCLC-21H [nTPM]":"58.3","Cell RNA - SH-SY5Y [nTPM]":"31.7","Cell RNA - SiHa [nTPM]":"60.8","Cell RNA - SK-BR-3 [nTPM]":"45.5","Cell RNA - SK-MEL-30 [nTPM]":"63.0","Cell RNA - SuSa [nTPM]":"74.9","Cell RNA - T-47d [nTPM]":"41.0","Cell RNA - THP-1 [nTPM]":"33.7","Cell RNA - TIME [nTPM]":"90.8","Cell RNA - U-138 MG [nTPM]":"99.5","Cell RNA - U-2 OS [nTPM]":"63.8","Cell RNA - U-2197 [nTPM]":"71.1","Cell RNA - U-251 MG [nTPM]":"112.4","Cell RNA - U-266\/70 [nTPM]":"74.0","Cell RNA - U-266\/84 [nTPM]":"143.1","Cell RNA - U-698 [nTPM]":"60.6","Cell RNA - U-87 MG [nTPM]":"105.1","Cell RNA - U-937 [nTPM]":"69.9","Cell RNA - WM-115 [nTPM]":"48.4","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"7.5","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"6.4","Blood RNA - intermediate monocyte [nTPM]":"7.7","Blood RNA - MAIT T-cell [nTPM]":"5.8","Blood RNA - memory B-cell [nTPM]":"2.8","Blood RNA - memory CD4 T-cell [nTPM]":"5.6","Blood RNA - memory CD8 T-cell [nTPM]":"6.1","Blood RNA - myeloid DC [nTPM]":"7.7","Blood RNA - naive B-cell [nTPM]":"4.6","Blood RNA - naive CD4 T-cell [nTPM]":"6.9","Blood RNA - naive CD8 T-cell [nTPM]":"4.2","Blood RNA - neutrophil [nTPM]":"3.5","Blood RNA - NK-cell [nTPM]":"8.3","Blood RNA - non-classical monocyte [nTPM]":"7.7","Blood RNA - plasmacytoid DC [nTPM]":"15.1","Blood RNA - T-reg [nTPM]":"4.6","Blood RNA - total PBMC [nTPM]":"2.8","Brain RNA - amygdala [nTPM]":"47.6","Brain RNA - basal ganglia [nTPM]":"79.7","Brain RNA - cerebellum [nTPM]":"30.2","Brain RNA - cerebral cortex [nTPM]":"61.3","Brain RNA - hippocampal formation [nTPM]":"69.4","Brain RNA - hypothalamus [nTPM]":"44.3","Brain RNA - medulla oblongata [nTPM]":"31.6","Brain RNA - midbrain [nTPM]":"32.6","Brain RNA - pons [nTPM]":"40.1","Brain RNA - spinal cord [nTPM]":"35.7","Brain RNA - thalamus [nTPM]":"42.8","Brain RNA - white matter [nTPM]":"49.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"24.8","Single Cell Type RNA - Astrocytes [nTPM]":"24.2","Single Cell Type RNA - B-cells [nTPM]":"40.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"82.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"45.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"21.1","Single Cell Type RNA - Bipolar cells [nTPM]":"10.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"21.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"40.0","Single Cell Type RNA - Club cells [nTPM]":"24.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.1","Single Cell Type RNA - dendritic cells [nTPM]":"45.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"69.4","Single Cell Type RNA - Early spermatids [nTPM]":"12.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"13.9","Single Cell Type RNA - Endothelial cells [nTPM]":"34.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"69.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"23.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"48.8","Single Cell Type RNA - Fibroblasts [nTPM]":"30.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"17.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.4","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"19.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"172.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.4","Single Cell Type RNA - Horizontal cells [nTPM]":"10.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"46.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.4","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"90.7","Single Cell Type RNA - Langerhans cells [nTPM]":"265.3","Single Cell Type RNA - Late spermatids [nTPM]":"23.6","Single Cell Type RNA - Leydig cells [nTPM]":"22.4","Single Cell Type RNA - Macrophages [nTPM]":"115.1","Single Cell Type RNA - Melanocytes [nTPM]":"53.4","Single Cell Type RNA - Microglial cells [nTPM]":"48.7","Single Cell Type RNA - monocytes [nTPM]":"87.9","Single Cell Type RNA - Muller glia cells [nTPM]":"34.9","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"103.9","Single Cell Type RNA - Paneth cells [nTPM]":"23.5","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"49.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"87.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"17.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"7.8","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"16.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"52.4","Single Cell Type RNA - Spermatocytes [nTPM]":"35.6","Single Cell Type RNA - Spermatogonia [nTPM]":"42.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"30.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"67.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"51.7","Single Cell Type RNA - T-cells [nTPM]":"54.0","Single Cell Type RNA - Theca cells [nTPM]":"5.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.1","Single Cell Type RNA - Urothelial cells [nTPM]":"65.4"},{"Gene":"MAP2K2","Gene synonym":["MEK2","PRKMK2"],"Ensembl":"ENSG00000126934","Gene description":"Mitogen-activated protein kinase kinase 2","Uniprot":["P36507"],"Chromosome":"19","Position":"4090321-4124122","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Cardiomyopathy","Disease variant","Ectodermal dysplasia","FDA approved drug targets","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"724.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003835","HPA051993"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"140000","Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 25: Spermatids - Spermatogenesis","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003835":"AB_562312","HPA051993":"AB_2681685"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.39e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.72e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.98e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.45e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.43e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"73.9","Tissue RNA - adrenal gland [nTPM]":"118.4","Tissue RNA - amygdala [nTPM]":"145.5","Tissue RNA - appendix [nTPM]":"54.1","Tissue RNA - basal ganglia [nTPM]":"143.1","Tissue RNA - bone marrow [nTPM]":"102.4","Tissue RNA - breast [nTPM]":"69.1","Tissue RNA - cerebellum [nTPM]":"151.5","Tissue RNA - cerebral cortex [nTPM]":"190.7","Tissue RNA - cervix [nTPM]":"76.6","Tissue RNA - choroid plexus [nTPM]":"150.4","Tissue RNA - colon [nTPM]":"103.4","Tissue RNA - duodenum [nTPM]":"134.0","Tissue RNA - endometrium 1 [nTPM]":"72.3","Tissue RNA - epididymis [nTPM]":"23.2","Tissue RNA - esophagus [nTPM]":"121.6","Tissue RNA - fallopian tube [nTPM]":"64.7","Tissue RNA - gallbladder [nTPM]":"30.4","Tissue RNA - heart muscle [nTPM]":"156.6","Tissue RNA - hippocampal formation [nTPM]":"145.9","Tissue RNA - hypothalamus [nTPM]":"147.3","Tissue RNA - kidney [nTPM]":"82.6","Tissue RNA - liver [nTPM]":"123.3","Tissue RNA - lung [nTPM]":"66.8","Tissue RNA - lymph node [nTPM]":"57.1","Tissue RNA - medulla oblongata [nTPM]":"149.6","Tissue RNA - midbrain [nTPM]":"152.9","Tissue RNA - ovary [nTPM]":"84.1","Tissue RNA - pancreas [nTPM]":"134.3","Tissue RNA - parathyroid gland [nTPM]":"54.9","Tissue RNA - pituitary gland [nTPM]":"99.3","Tissue RNA - placenta [nTPM]":"36.4","Tissue RNA - pons [nTPM]":"154.3","Tissue RNA - prostate [nTPM]":"93.9","Tissue RNA - rectum [nTPM]":"42.7","Tissue RNA - retina [nTPM]":"68.0","Tissue RNA - salivary gland [nTPM]":"79.6","Tissue RNA - seminal vesicle [nTPM]":"37.6","Tissue RNA - skeletal muscle [nTPM]":"289.0","Tissue RNA - skin 1 [nTPM]":"95.8","Tissue RNA - small intestine [nTPM]":"101.0","Tissue RNA - smooth muscle [nTPM]":"31.7","Tissue RNA - spinal cord [nTPM]":"143.5","Tissue RNA - spleen [nTPM]":"89.1","Tissue RNA - stomach 1 [nTPM]":"92.7","Tissue RNA - testis [nTPM]":"131.6","Tissue RNA - thalamus [nTPM]":"150.7","Tissue RNA - thymus [nTPM]":"69.3","Tissue RNA - thyroid gland [nTPM]":"74.6","Tissue RNA - tongue [nTPM]":"132.1","Tissue RNA - tonsil [nTPM]":"41.0","Tissue RNA - urinary bladder [nTPM]":"77.2","Tissue RNA - vagina [nTPM]":"75.2","Tissue RNA - white matter [nTPM]":"142.8","Cell RNA - A-431 [nTPM]":"163.1","Cell RNA - A549 [nTPM]":"175.4","Cell RNA - AF22 [nTPM]":"93.7","Cell RNA - AN3-CA [nTPM]":"132.8","Cell RNA - ASC diff [nTPM]":"127.1","Cell RNA - ASC TERT1 [nTPM]":"151.9","Cell RNA - BEWO [nTPM]":"93.8","Cell RNA - BJ [nTPM]":"104.5","Cell RNA - BJ hTERT+ [nTPM]":"138.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"139.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"125.8","Cell RNA - CACO-2 [nTPM]":"153.0","Cell RNA - CAPAN-2 [nTPM]":"85.5","Cell RNA - Daudi [nTPM]":"137.7","Cell RNA - EFO-21 [nTPM]":"95.9","Cell RNA - fHDF\/TERT166 [nTPM]":"120.0","Cell RNA - GAMG [nTPM]":"111.9","Cell RNA - HaCaT [nTPM]":"114.3","Cell RNA - HAP1 [nTPM]":"74.2","Cell RNA - HBEC3-KT [nTPM]":"111.6","Cell RNA - HBF TERT88 [nTPM]":"107.4","Cell RNA - HDLM-2 [nTPM]":"118.1","Cell RNA - HEK 293 [nTPM]":"90.4","Cell RNA - HEL [nTPM]":"50.5","Cell RNA - HeLa [nTPM]":"91.4","Cell RNA - Hep G2 [nTPM]":"171.7","Cell RNA - HHSteC [nTPM]":"194.0","Cell RNA - HL-60 [nTPM]":"93.6","Cell RNA - HMC-1 [nTPM]":"101.8","Cell RNA - HSkMC [nTPM]":"168.8","Cell RNA - hTCEpi [nTPM]":"106.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"98.2","Cell RNA - hTERT-HME1 [nTPM]":"129.5","Cell RNA - hTERT-RPE1 [nTPM]":"185.5","Cell RNA - HUVEC TERT2 [nTPM]":"125.2","Cell RNA - JURKAT [nTPM]":"123.0","Cell RNA - K-562 [nTPM]":"98.1","Cell RNA - Karpas-707 [nTPM]":"263.1","Cell RNA - LHCN-M2 [nTPM]":"119.3","Cell RNA - MCF7 [nTPM]":"203.5","Cell RNA - MOLT-4 [nTPM]":"186.3","Cell RNA - NB-4 [nTPM]":"130.6","Cell RNA - NTERA-2 [nTPM]":"107.8","Cell RNA - OE19 [nTPM]":"118.6","Cell RNA - PC-3 [nTPM]":"125.9","Cell RNA - REH [nTPM]":"140.7","Cell RNA - RH-30 [nTPM]":"61.9","Cell RNA - RPMI-8226 [nTPM]":"159.1","Cell RNA - RPTEC TERT1 [nTPM]":"123.5","Cell RNA - RT4 [nTPM]":"102.7","Cell RNA - SCLC-21H [nTPM]":"126.8","Cell RNA - SH-SY5Y [nTPM]":"126.3","Cell RNA - SiHa [nTPM]":"95.7","Cell RNA - SK-BR-3 [nTPM]":"130.6","Cell RNA - SK-MEL-30 [nTPM]":"344.1","Cell RNA - SuSa [nTPM]":"107.3","Cell RNA - T-47d [nTPM]":"101.0","Cell RNA - THP-1 [nTPM]":"158.5","Cell RNA - TIME [nTPM]":"111.8","Cell RNA - U-138 MG [nTPM]":"113.6","Cell RNA - U-2 OS [nTPM]":"98.2","Cell RNA - U-2197 [nTPM]":"293.4","Cell RNA - U-251 MG [nTPM]":"163.9","Cell RNA - U-266\/70 [nTPM]":"263.1","Cell RNA - U-266\/84 [nTPM]":"172.4","Cell RNA - U-698 [nTPM]":"100.2","Cell RNA - U-87 MG [nTPM]":"176.5","Cell RNA - U-937 [nTPM]":"166.8","Cell RNA - WM-115 [nTPM]":"199.3","Blood RNA - basophil [nTPM]":"27.5","Blood RNA - classical monocyte [nTPM]":"13.0","Blood RNA - eosinophil [nTPM]":"45.4","Blood RNA - gdT-cell [nTPM]":"16.9","Blood RNA - intermediate monocyte [nTPM]":"16.6","Blood RNA - MAIT T-cell [nTPM]":"13.6","Blood RNA - memory B-cell [nTPM]":"13.0","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"17.2","Blood RNA - myeloid DC [nTPM]":"15.9","Blood RNA - naive B-cell [nTPM]":"18.2","Blood RNA - naive CD4 T-cell [nTPM]":"12.3","Blood RNA - naive CD8 T-cell [nTPM]":"15.9","Blood RNA - neutrophil [nTPM]":"21.2","Blood RNA - NK-cell [nTPM]":"18.8","Blood RNA - non-classical monocyte [nTPM]":"14.1","Blood RNA - plasmacytoid DC [nTPM]":"9.0","Blood RNA - T-reg [nTPM]":"14.3","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"145.5","Brain RNA - basal ganglia [nTPM]":"143.1","Brain RNA - cerebellum [nTPM]":"151.5","Brain RNA - cerebral cortex [nTPM]":"190.7","Brain RNA - hippocampal formation [nTPM]":"145.9","Brain RNA - hypothalamus [nTPM]":"147.3","Brain RNA - medulla oblongata [nTPM]":"149.6","Brain RNA - midbrain [nTPM]":"152.9","Brain RNA - pons [nTPM]":"154.3","Brain RNA - spinal cord [nTPM]":"143.5","Brain RNA - thalamus [nTPM]":"150.7","Brain RNA - white matter [nTPM]":"142.8","Single Cell Type RNA - Adipocytes [nTPM]":"77.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.9","Single Cell Type RNA - Astrocytes [nTPM]":"22.5","Single Cell Type RNA - B-cells [nTPM]":"62.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"35.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"21.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"85.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"92.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"95.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"62.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"22.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"28.7","Single Cell Type RNA - dendritic cells [nTPM]":"102.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"300.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"146.8","Single Cell Type RNA - Ductal cells [nTPM]":"20.7","Single Cell Type RNA - Early spermatids [nTPM]":"248.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"59.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"68.3","Single Cell Type RNA - Endothelial cells [nTPM]":"52.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"63.2","Single Cell Type RNA - Erythroid cells [nTPM]":"123.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"45.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.6","Single Cell Type RNA - Fibroblasts [nTPM]":"60.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"64.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"48.8","Single Cell Type RNA - granulocytes [nTPM]":"19.7","Single Cell Type RNA - Granulosa cells [nTPM]":"124.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"49.2","Single Cell Type RNA - Hepatocytes [nTPM]":"48.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"55.0","Single Cell Type RNA - Horizontal cells [nTPM]":"121.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"23.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"107.7","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"56.0","Single Cell Type RNA - Langerhans cells [nTPM]":"38.2","Single Cell Type RNA - Late spermatids [nTPM]":"724.3","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"65.6","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"28.5","Single Cell Type RNA - Muller glia cells [nTPM]":"121.1","Single Cell Type RNA - NK-cells [nTPM]":"62.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"13.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.0","Single Cell Type RNA - Paneth cells [nTPM]":"151.8","Single Cell Type RNA - Peritubular cells [nTPM]":"23.0","Single Cell Type RNA - Plasma cells [nTPM]":"79.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"103.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"166.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"92.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"106.8","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"93.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"71.8","Single Cell Type RNA - Spermatocytes [nTPM]":"23.5","Single Cell Type RNA - Spermatogonia [nTPM]":"17.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"42.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"63.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.6","Single Cell Type RNA - T-cells [nTPM]":"77.0","Single Cell Type RNA - Theca cells [nTPM]":"120.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"119.9","Single Cell Type RNA - Urothelial cells [nTPM]":"113.1"},{"Gene":"MAX","Gene synonym":["bHLHd4","bHLHd5","bHLHd6","bHLHd7","bHLHd8"],"Ensembl":"ENSG00000125952","Gene description":"MYC associated factor X","Uniprot":["P61244"],"Chromosome":"14","Position":"65006174-65102695","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"390.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000328","HPA003474"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"CAB000328":"AB_2281783","HPA003474":"AB_1079317"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.08e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.36e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.57e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.68e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.12e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.1","Tissue RNA - adrenal gland [nTPM]":"36.3","Tissue RNA - amygdala [nTPM]":"57.4","Tissue RNA - appendix [nTPM]":"43.5","Tissue RNA - basal ganglia [nTPM]":"63.2","Tissue RNA - bone marrow [nTPM]":"105.1","Tissue RNA - breast [nTPM]":"41.2","Tissue RNA - cerebellum [nTPM]":"74.6","Tissue RNA - cerebral cortex [nTPM]":"62.9","Tissue RNA - cervix [nTPM]":"61.0","Tissue RNA - choroid plexus [nTPM]":"44.8","Tissue RNA - colon [nTPM]":"51.1","Tissue RNA - duodenum [nTPM]":"41.3","Tissue RNA - endometrium 1 [nTPM]":"51.1","Tissue RNA - epididymis [nTPM]":"29.2","Tissue RNA - esophagus [nTPM]":"75.8","Tissue RNA - fallopian tube [nTPM]":"67.2","Tissue RNA - gallbladder [nTPM]":"36.2","Tissue RNA - heart muscle [nTPM]":"52.8","Tissue RNA - hippocampal formation [nTPM]":"55.0","Tissue RNA - hypothalamus [nTPM]":"59.4","Tissue RNA - kidney [nTPM]":"39.5","Tissue RNA - liver [nTPM]":"36.8","Tissue RNA - lung [nTPM]":"51.6","Tissue RNA - lymph node [nTPM]":"63.7","Tissue RNA - medulla oblongata [nTPM]":"65.5","Tissue RNA - midbrain [nTPM]":"61.8","Tissue RNA - ovary [nTPM]":"56.2","Tissue RNA - pancreas [nTPM]":"29.3","Tissue RNA - parathyroid gland [nTPM]":"31.3","Tissue RNA - pituitary gland [nTPM]":"32.5","Tissue RNA - placenta [nTPM]":"39.8","Tissue RNA - pons [nTPM]":"65.0","Tissue RNA - prostate [nTPM]":"52.2","Tissue RNA - rectum [nTPM]":"31.8","Tissue RNA - retina [nTPM]":"23.6","Tissue RNA - salivary gland [nTPM]":"43.5","Tissue RNA - seminal vesicle [nTPM]":"38.7","Tissue RNA - skeletal muscle [nTPM]":"43.8","Tissue RNA - skin 1 [nTPM]":"55.3","Tissue RNA - small intestine [nTPM]":"51.7","Tissue RNA - smooth muscle [nTPM]":"39.5","Tissue RNA - spinal cord [nTPM]":"59.4","Tissue RNA - spleen [nTPM]":"66.3","Tissue RNA - stomach 1 [nTPM]":"39.4","Tissue RNA - testis [nTPM]":"21.5","Tissue RNA - thalamus [nTPM]":"62.1","Tissue RNA - thymus [nTPM]":"63.7","Tissue RNA - thyroid gland [nTPM]":"42.7","Tissue RNA - tongue [nTPM]":"54.0","Tissue RNA - tonsil [nTPM]":"55.1","Tissue RNA - urinary bladder [nTPM]":"51.3","Tissue RNA - vagina [nTPM]":"68.7","Tissue RNA - white matter [nTPM]":"65.3","Cell RNA - A-431 [nTPM]":"117.1","Cell RNA - A549 [nTPM]":"40.4","Cell RNA - AF22 [nTPM]":"27.8","Cell RNA - AN3-CA [nTPM]":"44.6","Cell RNA - ASC diff [nTPM]":"73.4","Cell RNA - ASC TERT1 [nTPM]":"58.0","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"39.9","Cell RNA - BJ hTERT+ [nTPM]":"62.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"47.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.4","Cell RNA - CACO-2 [nTPM]":"29.1","Cell RNA - CAPAN-2 [nTPM]":"86.7","Cell RNA - Daudi [nTPM]":"88.1","Cell RNA - EFO-21 [nTPM]":"33.1","Cell RNA - fHDF\/TERT166 [nTPM]":"48.8","Cell RNA - GAMG [nTPM]":"45.0","Cell RNA - HaCaT [nTPM]":"60.4","Cell RNA - HAP1 [nTPM]":"63.4","Cell RNA - HBEC3-KT [nTPM]":"52.7","Cell RNA - HBF TERT88 [nTPM]":"37.3","Cell RNA - HDLM-2 [nTPM]":"84.5","Cell RNA - HEK 293 [nTPM]":"40.5","Cell RNA - HEL [nTPM]":"143.4","Cell RNA - HeLa [nTPM]":"29.9","Cell RNA - Hep G2 [nTPM]":"32.0","Cell RNA - HHSteC [nTPM]":"90.9","Cell RNA - HL-60 [nTPM]":"56.2","Cell RNA - HMC-1 [nTPM]":"390.3","Cell RNA - HSkMC [nTPM]":"67.6","Cell RNA - hTCEpi [nTPM]":"43.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"42.7","Cell RNA - hTERT-HME1 [nTPM]":"54.9","Cell RNA - hTERT-RPE1 [nTPM]":"71.9","Cell RNA - HUVEC TERT2 [nTPM]":"54.9","Cell RNA - JURKAT [nTPM]":"71.8","Cell RNA - K-562 [nTPM]":"66.8","Cell RNA - Karpas-707 [nTPM]":"42.4","Cell RNA - LHCN-M2 [nTPM]":"53.1","Cell RNA - MCF7 [nTPM]":"63.9","Cell RNA - MOLT-4 [nTPM]":"140.1","Cell RNA - NB-4 [nTPM]":"217.6","Cell RNA - NTERA-2 [nTPM]":"36.3","Cell RNA - OE19 [nTPM]":"71.3","Cell RNA - PC-3 [nTPM]":"70.6","Cell RNA - REH [nTPM]":"75.2","Cell RNA - RH-30 [nTPM]":"42.7","Cell RNA - RPMI-8226 [nTPM]":"47.3","Cell RNA - RPTEC TERT1 [nTPM]":"49.2","Cell RNA - RT4 [nTPM]":"38.8","Cell RNA - SCLC-21H [nTPM]":"61.8","Cell RNA - SH-SY5Y [nTPM]":"38.2","Cell RNA - SiHa [nTPM]":"49.6","Cell RNA - SK-BR-3 [nTPM]":"60.6","Cell RNA - SK-MEL-30 [nTPM]":"60.4","Cell RNA - SuSa [nTPM]":"25.1","Cell RNA - T-47d [nTPM]":"58.0","Cell RNA - THP-1 [nTPM]":"71.6","Cell RNA - TIME [nTPM]":"69.7","Cell RNA - U-138 MG [nTPM]":"47.8","Cell RNA - U-2 OS [nTPM]":"55.8","Cell RNA - U-2197 [nTPM]":"42.0","Cell RNA - U-251 MG [nTPM]":"33.6","Cell RNA - U-266\/70 [nTPM]":"50.7","Cell RNA - U-266\/84 [nTPM]":"43.6","Cell RNA - U-698 [nTPM]":"61.7","Cell RNA - U-87 MG [nTPM]":"56.9","Cell RNA - U-937 [nTPM]":"56.1","Cell RNA - WM-115 [nTPM]":"46.0","Blood RNA - basophil [nTPM]":"667.6","Blood RNA - classical monocyte [nTPM]":"141.9","Blood RNA - eosinophil [nTPM]":"540.8","Blood RNA - gdT-cell [nTPM]":"125.7","Blood RNA - intermediate monocyte [nTPM]":"126.4","Blood RNA - MAIT T-cell [nTPM]":"140.1","Blood RNA - memory B-cell [nTPM]":"115.7","Blood RNA - memory CD4 T-cell [nTPM]":"147.5","Blood RNA - memory CD8 T-cell [nTPM]":"130.5","Blood RNA - myeloid DC [nTPM]":"119.9","Blood RNA - naive B-cell [nTPM]":"114.9","Blood RNA - naive CD4 T-cell [nTPM]":"151.1","Blood RNA - naive CD8 T-cell [nTPM]":"127.9","Blood RNA - neutrophil [nTPM]":"305.1","Blood RNA - NK-cell [nTPM]":"126.9","Blood RNA - non-classical monocyte [nTPM]":"120.3","Blood RNA - plasmacytoid DC [nTPM]":"114.6","Blood RNA - T-reg [nTPM]":"194.0","Blood RNA - total PBMC [nTPM]":"314.2","Brain RNA - amygdala [nTPM]":"57.4","Brain RNA - basal ganglia [nTPM]":"63.2","Brain RNA - cerebellum [nTPM]":"74.6","Brain RNA - cerebral cortex [nTPM]":"62.9","Brain RNA - hippocampal formation [nTPM]":"55.0","Brain RNA - hypothalamus [nTPM]":"59.4","Brain RNA - medulla oblongata [nTPM]":"65.5","Brain RNA - midbrain [nTPM]":"61.8","Brain RNA - pons [nTPM]":"65.0","Brain RNA - spinal cord [nTPM]":"59.4","Brain RNA - thalamus [nTPM]":"62.1","Brain RNA - white matter [nTPM]":"65.3","Single Cell Type RNA - Adipocytes [nTPM]":"45.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"27.4","Single Cell Type RNA - Astrocytes [nTPM]":"31.0","Single Cell Type RNA - B-cells [nTPM]":"74.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"170.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"66.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"63.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"126.3","Single Cell Type RNA - Bipolar cells [nTPM]":"28.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"59.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"43.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"32.9","Single Cell Type RNA - Club cells [nTPM]":"42.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"38.4","Single Cell Type RNA - dendritic cells [nTPM]":"79.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"116.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"38.8","Single Cell Type RNA - Early spermatids [nTPM]":"45.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"38.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"43.6","Single Cell Type RNA - Endothelial cells [nTPM]":"59.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"44.3","Single Cell Type RNA - Erythroid cells [nTPM]":"40.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"50.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"43.4","Single Cell Type RNA - Fibroblasts [nTPM]":"46.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"36.0","Single Cell Type RNA - granulocytes [nTPM]":"62.8","Single Cell Type RNA - Granulosa cells [nTPM]":"38.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"71.0","Single Cell Type RNA - Hepatocytes [nTPM]":"23.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"59.9","Single Cell Type RNA - Horizontal cells [nTPM]":"47.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"43.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.7","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"81.8","Single Cell Type RNA - Langerhans cells [nTPM]":"66.7","Single Cell Type RNA - Late spermatids [nTPM]":"115.6","Single Cell Type RNA - Leydig cells [nTPM]":"77.9","Single Cell Type RNA - Macrophages [nTPM]":"147.2","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"67.1","Single Cell Type RNA - Muller glia cells [nTPM]":"47.3","Single Cell Type RNA - NK-cells [nTPM]":"69.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"28.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"60.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"61.6","Single Cell Type RNA - Paneth cells [nTPM]":"96.7","Single Cell Type RNA - Peritubular cells [nTPM]":"60.2","Single Cell Type RNA - Plasma cells [nTPM]":"58.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"80.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"100.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"66.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.9","Single Cell Type RNA - Sertoli cells [nTPM]":"138.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"76.3","Single Cell Type RNA - Spermatocytes [nTPM]":"43.2","Single Cell Type RNA - Spermatogonia [nTPM]":"28.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"84.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"180.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"54.0","Single Cell Type RNA - T-cells [nTPM]":"83.9","Single Cell Type RNA - Theca cells [nTPM]":"25.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"29.7","Single Cell Type RNA - Urothelial cells [nTPM]":"76.2"},{"Gene":"MC2R","Gene synonym":["ACTHR"],"Ensembl":"ENSG00000185231","Gene description":"Melanocortin 2 receptor","Uniprot":["Q01718"],"Chromosome":"18","Position":"13882044-13915707","Protein class":["Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"33","RNA tissue specific nTPM":{"adrenal gland":"57.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"1.4"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA079148"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 17: Adrenal gland - Steroid metabolism","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA079148":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"57.9","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.1","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.2","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"1.7","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.2","Tissue RNA - pituitary gland [nTPM]":"1.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.1","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.4","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.2","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MDM2","Gene synonym":["HDM2","MGC5370"],"Ensembl":"ENSG00000135679","Gene description":"MDM2 proto-oncogene","Uniprot":["Q00987"],"Chromosome":"12","Position":"68808177-68850686","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Host-virus interaction","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial ciliated cells":"257.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HBEC3-KT":"504.6","U-698":"517.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000086","CAB016303","CAB079977"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 49: Ciliated cells - Cilium organization","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB000086":"AB_563872","CAB016303":"AB_627920","CAB079977":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.23e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.16e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.51e-7"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.25e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.45e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.23e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.22e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.95e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"11.6","Tissue RNA - amygdala [nTPM]":"5.4","Tissue RNA - appendix [nTPM]":"10.4","Tissue RNA - basal ganglia [nTPM]":"10.0","Tissue RNA - bone marrow [nTPM]":"28.6","Tissue RNA - breast [nTPM]":"11.9","Tissue RNA - cerebellum [nTPM]":"7.4","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"13.9","Tissue RNA - choroid plexus [nTPM]":"28.0","Tissue RNA - colon [nTPM]":"20.7","Tissue RNA - duodenum [nTPM]":"6.4","Tissue RNA - endometrium 1 [nTPM]":"9.5","Tissue RNA - epididymis [nTPM]":"7.1","Tissue RNA - esophagus [nTPM]":"13.0","Tissue RNA - fallopian tube [nTPM]":"14.1","Tissue RNA - gallbladder [nTPM]":"12.0","Tissue RNA - heart muscle [nTPM]":"6.8","Tissue RNA - hippocampal formation [nTPM]":"3.8","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"9.5","Tissue RNA - liver [nTPM]":"26.9","Tissue RNA - lung [nTPM]":"14.3","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"9.9","Tissue RNA - midbrain [nTPM]":"8.5","Tissue RNA - ovary [nTPM]":"10.8","Tissue RNA - pancreas [nTPM]":"14.3","Tissue RNA - parathyroid gland [nTPM]":"10.9","Tissue RNA - pituitary gland [nTPM]":"5.0","Tissue RNA - placenta [nTPM]":"16.4","Tissue RNA - pons [nTPM]":"9.2","Tissue RNA - prostate [nTPM]":"11.3","Tissue RNA - rectum [nTPM]":"21.9","Tissue RNA - retina [nTPM]":"14.2","Tissue RNA - salivary gland [nTPM]":"9.6","Tissue RNA - seminal vesicle [nTPM]":"11.5","Tissue RNA - skeletal muscle [nTPM]":"18.6","Tissue RNA - skin 1 [nTPM]":"10.9","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"12.4","Tissue RNA - spinal cord [nTPM]":"6.0","Tissue RNA - spleen [nTPM]":"11.4","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"6.6","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"15.6","Tissue RNA - thyroid gland [nTPM]":"15.4","Tissue RNA - tongue [nTPM]":"12.9","Tissue RNA - tonsil [nTPM]":"17.0","Tissue RNA - urinary bladder [nTPM]":"15.1","Tissue RNA - vagina [nTPM]":"10.8","Tissue RNA - white matter [nTPM]":"12.8","Cell RNA - A-431 [nTPM]":"18.7","Cell RNA - A549 [nTPM]":"42.1","Cell RNA - AF22 [nTPM]":"43.5","Cell RNA - AN3-CA [nTPM]":"22.6","Cell RNA - ASC diff [nTPM]":"55.9","Cell RNA - ASC TERT1 [nTPM]":"51.5","Cell RNA - BEWO [nTPM]":"223.4","Cell RNA - BJ [nTPM]":"49.7","Cell RNA - BJ hTERT+ [nTPM]":"50.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"26.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.5","Cell RNA - CACO-2 [nTPM]":"26.8","Cell RNA - CAPAN-2 [nTPM]":"8.4","Cell RNA - Daudi [nTPM]":"188.6","Cell RNA - EFO-21 [nTPM]":"13.5","Cell RNA - fHDF\/TERT166 [nTPM]":"34.7","Cell RNA - GAMG [nTPM]":"7.3","Cell RNA - HaCaT [nTPM]":"11.0","Cell RNA - HAP1 [nTPM]":"31.4","Cell RNA - HBEC3-KT [nTPM]":"504.6","Cell RNA - HBF TERT88 [nTPM]":"42.1","Cell RNA - HDLM-2 [nTPM]":"51.0","Cell RNA - HEK 293 [nTPM]":"22.0","Cell RNA - HEL [nTPM]":"35.3","Cell RNA - HeLa [nTPM]":"36.0","Cell RNA - Hep G2 [nTPM]":"115.0","Cell RNA - HHSteC [nTPM]":"55.7","Cell RNA - HL-60 [nTPM]":"32.6","Cell RNA - HMC-1 [nTPM]":"31.0","Cell RNA - HSkMC [nTPM]":"77.8","Cell RNA - hTCEpi [nTPM]":"46.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"101.5","Cell RNA - hTERT-HME1 [nTPM]":"69.4","Cell RNA - hTERT-RPE1 [nTPM]":"26.9","Cell RNA - HUVEC TERT2 [nTPM]":"73.7","Cell RNA - JURKAT [nTPM]":"32.1","Cell RNA - K-562 [nTPM]":"37.1","Cell RNA - Karpas-707 [nTPM]":"45.4","Cell RNA - LHCN-M2 [nTPM]":"50.8","Cell RNA - MCF7 [nTPM]":"28.0","Cell RNA - MOLT-4 [nTPM]":"43.1","Cell RNA - NB-4 [nTPM]":"10.7","Cell RNA - NTERA-2 [nTPM]":"36.9","Cell RNA - OE19 [nTPM]":"10.1","Cell RNA - PC-3 [nTPM]":"8.2","Cell RNA - REH [nTPM]":"149.4","Cell RNA - RH-30 [nTPM]":"31.7","Cell RNA - RPMI-8226 [nTPM]":"16.2","Cell RNA - RPTEC TERT1 [nTPM]":"16.0","Cell RNA - RT4 [nTPM]":"146.0","Cell RNA - SCLC-21H [nTPM]":"34.3","Cell RNA - SH-SY5Y [nTPM]":"20.2","Cell RNA - SiHa [nTPM]":"32.0","Cell RNA - SK-BR-3 [nTPM]":"25.0","Cell RNA - SK-MEL-30 [nTPM]":"11.3","Cell RNA - SuSa [nTPM]":"88.8","Cell RNA - T-47d [nTPM]":"58.3","Cell RNA - THP-1 [nTPM]":"21.4","Cell RNA - TIME [nTPM]":"82.3","Cell RNA - U-138 MG [nTPM]":"20.2","Cell RNA - U-2 OS [nTPM]":"38.0","Cell RNA - U-2197 [nTPM]":"16.8","Cell RNA - U-251 MG [nTPM]":"18.5","Cell RNA - U-266\/70 [nTPM]":"68.2","Cell RNA - U-266\/84 [nTPM]":"47.7","Cell RNA - U-698 [nTPM]":"517.6","Cell RNA - U-87 MG [nTPM]":"31.3","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"81.2","Blood RNA - basophil [nTPM]":"6.1","Blood RNA - classical monocyte [nTPM]":"5.4","Blood RNA - eosinophil [nTPM]":"5.2","Blood RNA - gdT-cell [nTPM]":"4.1","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"3.7","Blood RNA - memory B-cell [nTPM]":"4.7","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"4.1","Blood RNA - myeloid DC [nTPM]":"3.0","Blood RNA - naive B-cell [nTPM]":"5.4","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"3.5","Blood RNA - neutrophil [nTPM]":"19.2","Blood RNA - NK-cell [nTPM]":"3.7","Blood RNA - non-classical monocyte [nTPM]":"7.2","Blood RNA - plasmacytoid DC [nTPM]":"3.9","Blood RNA - T-reg [nTPM]":"4.1","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"5.4","Brain RNA - basal ganglia [nTPM]":"10.0","Brain RNA - cerebellum [nTPM]":"7.4","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"3.8","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"9.9","Brain RNA - midbrain [nTPM]":"8.5","Brain RNA - pons [nTPM]":"9.2","Brain RNA - spinal cord [nTPM]":"6.0","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"12.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.3","Single Cell Type RNA - Astrocytes [nTPM]":"26.1","Single Cell Type RNA - B-cells [nTPM]":"36.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"30.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"42.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"26.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"21.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"17.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"20.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"75.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"33.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"47.5","Single Cell Type RNA - dendritic cells [nTPM]":"32.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"19.5","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"257.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.5","Single Cell Type RNA - Endothelial cells [nTPM]":"22.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"25.1","Single Cell Type RNA - Erythroid cells [nTPM]":"29.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"28.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.0","Single Cell Type RNA - Fibroblasts [nTPM]":"31.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"74.8","Single Cell Type RNA - granulocytes [nTPM]":"32.9","Single Cell Type RNA - Granulosa cells [nTPM]":"33.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.7","Single Cell Type RNA - Hepatocytes [nTPM]":"45.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"18.3","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"23.4","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"49.0","Single Cell Type RNA - Langerhans cells [nTPM]":"25.0","Single Cell Type RNA - Late spermatids [nTPM]":"2.9","Single Cell Type RNA - Leydig cells [nTPM]":"19.3","Single Cell Type RNA - Macrophages [nTPM]":"44.9","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"37.5","Single Cell Type RNA - monocytes [nTPM]":"35.4","Single Cell Type RNA - Muller glia cells [nTPM]":"27.8","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"25.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"71.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"22.4","Single Cell Type RNA - Paneth cells [nTPM]":"20.1","Single Cell Type RNA - Peritubular cells [nTPM]":"15.1","Single Cell Type RNA - Plasma cells [nTPM]":"117.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"39.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"21.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"141.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"35.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"30.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.4","Single Cell Type RNA - Spermatocytes [nTPM]":"17.3","Single Cell Type RNA - Spermatogonia [nTPM]":"20.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"59.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"94.3","Single Cell Type RNA - T-cells [nTPM]":"31.8","Single Cell Type RNA - Theca cells [nTPM]":"49.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"82.0"},{"Gene":"MDM4","Gene synonym":["HDMX","MDMX"],"Ensembl":"ENSG00000198625","Gene description":"MDM4 regulator of p53","Uniprot":["O15151"],"Chromosome":"1","Position":"204516379-204558120","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"58.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA018919","HPA048821"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA018919":"AB_1853694","HPA048821":"AB_2680531"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.73e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.38e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.34e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.87e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.06e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.49e-4"},"Tissue RNA - adipose tissue [nTPM]":"13.7","Tissue RNA - adrenal gland [nTPM]":"10.5","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"13.4","Tissue RNA - basal ganglia [nTPM]":"18.7","Tissue RNA - bone marrow [nTPM]":"56.1","Tissue RNA - breast [nTPM]":"14.3","Tissue RNA - cerebellum [nTPM]":"16.3","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"17.6","Tissue RNA - choroid plexus [nTPM]":"35.0","Tissue RNA - colon [nTPM]":"12.4","Tissue RNA - duodenum [nTPM]":"5.8","Tissue RNA - endometrium 1 [nTPM]":"12.0","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"11.5","Tissue RNA - fallopian tube [nTPM]":"13.6","Tissue RNA - gallbladder [nTPM]":"6.7","Tissue RNA - heart muscle [nTPM]":"11.4","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"14.4","Tissue RNA - liver [nTPM]":"14.8","Tissue RNA - lung [nTPM]":"16.3","Tissue RNA - lymph node [nTPM]":"18.8","Tissue RNA - medulla oblongata [nTPM]":"17.5","Tissue RNA - midbrain [nTPM]":"14.6","Tissue RNA - ovary [nTPM]":"18.9","Tissue RNA - pancreas [nTPM]":"18.8","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"16.3","Tissue RNA - placenta [nTPM]":"10.1","Tissue RNA - pons [nTPM]":"17.5","Tissue RNA - prostate [nTPM]":"14.6","Tissue RNA - rectum [nTPM]":"9.6","Tissue RNA - retina [nTPM]":"25.2","Tissue RNA - salivary gland [nTPM]":"11.9","Tissue RNA - seminal vesicle [nTPM]":"7.3","Tissue RNA - skeletal muscle [nTPM]":"10.5","Tissue RNA - skin 1 [nTPM]":"20.7","Tissue RNA - small intestine [nTPM]":"16.7","Tissue RNA - smooth muscle [nTPM]":"7.1","Tissue RNA - spinal cord [nTPM]":"10.5","Tissue RNA - spleen [nTPM]":"22.6","Tissue RNA - stomach 1 [nTPM]":"13.2","Tissue RNA - testis [nTPM]":"19.9","Tissue RNA - thalamus [nTPM]":"15.9","Tissue RNA - thymus [nTPM]":"30.4","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"4.2","Tissue RNA - tonsil [nTPM]":"17.4","Tissue RNA - urinary bladder [nTPM]":"12.1","Tissue RNA - vagina [nTPM]":"13.7","Tissue RNA - white matter [nTPM]":"36.0","Cell RNA - A-431 [nTPM]":"6.5","Cell RNA - A549 [nTPM]":"12.7","Cell RNA - AF22 [nTPM]":"12.5","Cell RNA - AN3-CA [nTPM]":"17.3","Cell RNA - ASC diff [nTPM]":"8.6","Cell RNA - ASC TERT1 [nTPM]":"9.4","Cell RNA - BEWO [nTPM]":"58.7","Cell RNA - BJ [nTPM]":"4.8","Cell RNA - BJ hTERT+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"8.9","Cell RNA - CACO-2 [nTPM]":"6.6","Cell RNA - CAPAN-2 [nTPM]":"8.7","Cell RNA - Daudi [nTPM]":"22.4","Cell RNA - EFO-21 [nTPM]":"4.5","Cell RNA - fHDF\/TERT166 [nTPM]":"6.7","Cell RNA - GAMG [nTPM]":"5.1","Cell RNA - HaCaT [nTPM]":"6.8","Cell RNA - HAP1 [nTPM]":"8.5","Cell RNA - HBEC3-KT [nTPM]":"7.2","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"6.8","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"17.8","Cell RNA - HeLa [nTPM]":"32.0","Cell RNA - Hep G2 [nTPM]":"7.6","Cell RNA - HHSteC [nTPM]":"6.5","Cell RNA - HL-60 [nTPM]":"14.0","Cell RNA - HMC-1 [nTPM]":"16.9","Cell RNA - HSkMC [nTPM]":"9.4","Cell RNA - hTCEpi [nTPM]":"4.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.9","Cell RNA - hTERT-HME1 [nTPM]":"17.4","Cell RNA - hTERT-RPE1 [nTPM]":"6.3","Cell RNA - HUVEC TERT2 [nTPM]":"6.0","Cell RNA - JURKAT [nTPM]":"14.2","Cell RNA - K-562 [nTPM]":"10.4","Cell RNA - Karpas-707 [nTPM]":"31.5","Cell RNA - LHCN-M2 [nTPM]":"5.4","Cell RNA - MCF7 [nTPM]":"21.9","Cell RNA - MOLT-4 [nTPM]":"8.6","Cell RNA - NB-4 [nTPM]":"12.3","Cell RNA - NTERA-2 [nTPM]":"17.3","Cell RNA - OE19 [nTPM]":"2.4","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"10.1","Cell RNA - RH-30 [nTPM]":"10.2","Cell RNA - RPMI-8226 [nTPM]":"7.5","Cell RNA - RPTEC TERT1 [nTPM]":"6.0","Cell RNA - RT4 [nTPM]":"31.1","Cell RNA - SCLC-21H [nTPM]":"5.6","Cell RNA - SH-SY5Y [nTPM]":"12.6","Cell RNA - SiHa [nTPM]":"4.9","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"9.1","Cell RNA - SuSa [nTPM]":"12.4","Cell RNA - T-47d [nTPM]":"18.0","Cell RNA - THP-1 [nTPM]":"8.1","Cell RNA - TIME [nTPM]":"6.1","Cell RNA - U-138 MG [nTPM]":"6.8","Cell RNA - U-2 OS [nTPM]":"12.1","Cell RNA - U-2197 [nTPM]":"4.5","Cell RNA - U-251 MG [nTPM]":"7.9","Cell RNA - U-266\/70 [nTPM]":"15.8","Cell RNA - U-266\/84 [nTPM]":"6.2","Cell RNA - U-698 [nTPM]":"18.2","Cell RNA - U-87 MG [nTPM]":"4.7","Cell RNA - U-937 [nTPM]":"5.9","Cell RNA - WM-115 [nTPM]":"10.1","Blood RNA - basophil [nTPM]":"7.5","Blood RNA - classical monocyte [nTPM]":"4.3","Blood RNA - eosinophil [nTPM]":"5.8","Blood RNA - gdT-cell [nTPM]":"5.7","Blood RNA - intermediate monocyte [nTPM]":"4.2","Blood RNA - MAIT T-cell [nTPM]":"4.9","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.1","Blood RNA - myeloid DC [nTPM]":"3.6","Blood RNA - naive B-cell [nTPM]":"11.9","Blood RNA - naive CD4 T-cell [nTPM]":"6.1","Blood RNA - naive CD8 T-cell [nTPM]":"5.4","Blood RNA - neutrophil [nTPM]":"6.4","Blood RNA - NK-cell [nTPM]":"4.1","Blood RNA - non-classical monocyte [nTPM]":"3.8","Blood RNA - plasmacytoid DC [nTPM]":"7.8","Blood RNA - T-reg [nTPM]":"2.6","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"18.7","Brain RNA - cerebellum [nTPM]":"16.3","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"17.5","Brain RNA - midbrain [nTPM]":"14.6","Brain RNA - pons [nTPM]":"17.5","Brain RNA - spinal cord [nTPM]":"10.5","Brain RNA - thalamus [nTPM]":"15.9","Brain RNA - white matter [nTPM]":"36.0","Single Cell Type RNA - Adipocytes [nTPM]":"73.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"56.9","Single Cell Type RNA - Astrocytes [nTPM]":"76.0","Single Cell Type RNA - B-cells [nTPM]":"118.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"61.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"96.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"55.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"51.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"69.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"168.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"52.0","Single Cell Type RNA - dendritic cells [nTPM]":"135.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"35.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"29.9","Single Cell Type RNA - Early spermatids [nTPM]":"82.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"39.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"74.2","Single Cell Type RNA - Endothelial cells [nTPM]":"54.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"65.0","Single Cell Type RNA - Erythroid cells [nTPM]":"64.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"61.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.1","Single Cell Type RNA - Fibroblasts [nTPM]":"53.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"36.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"63.2","Single Cell Type RNA - granulocytes [nTPM]":"65.9","Single Cell Type RNA - Granulosa cells [nTPM]":"82.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"87.1","Single Cell Type RNA - Hepatocytes [nTPM]":"61.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.5","Single Cell Type RNA - Horizontal cells [nTPM]":"42.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"65.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"48.3","Single Cell Type RNA - Ionocytes [nTPM]":"54.9","Single Cell Type RNA - Kupffer cells [nTPM]":"96.4","Single Cell Type RNA - Langerhans cells [nTPM]":"128.3","Single Cell Type RNA - Late spermatids [nTPM]":"160.2","Single Cell Type RNA - Leydig cells [nTPM]":"80.2","Single Cell Type RNA - Macrophages [nTPM]":"62.0","Single Cell Type RNA - Melanocytes [nTPM]":"42.7","Single Cell Type RNA - Microglial cells [nTPM]":"83.4","Single Cell Type RNA - monocytes [nTPM]":"81.8","Single Cell Type RNA - Muller glia cells [nTPM]":"40.1","Single Cell Type RNA - NK-cells [nTPM]":"90.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"106.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"170.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"26.5","Single Cell Type RNA - Paneth cells [nTPM]":"42.3","Single Cell Type RNA - Peritubular cells [nTPM]":"54.2","Single Cell Type RNA - Plasma cells [nTPM]":"81.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"66.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"49.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"32.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"192.7","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"99.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.5","Single Cell Type RNA - Spermatocytes [nTPM]":"75.7","Single Cell Type RNA - Spermatogonia [nTPM]":"64.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"23.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"68.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"60.9","Single Cell Type RNA - T-cells [nTPM]":"73.7","Single Cell Type RNA - Theca cells [nTPM]":"58.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"51.1","Single Cell Type RNA - Urothelial cells [nTPM]":"48.3"},{"Gene":"MECOM","Gene synonym":["EVI1","KMT8E","MDS1","MDS1-EVI1","PRDM3"],"Ensembl":"ENSG00000085276","Gene description":"MDS1 and EVI1 complex locus","Uniprot":["Q03112"],"Chromosome":"3","Position":"169083499-169663775","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Apoptosis","Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"stomach 1":"73.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"184.8","Collecting duct cells":"125.0","Gastric mucus-secreting cells":"111.1","Glandular and luminal cells":"107.7","Microglial cells":"346.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"plasmacytoid DC":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HUVEC TERT2":"55.5","RPTEC TERT1":"71.2","RT4":"119.6","TIME":"53.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA046537"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA046537":"AB_2679689"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.09e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.59e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.54e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-3"},"Tissue RNA - adipose tissue [nTPM]":"16.0","Tissue RNA - adrenal gland [nTPM]":"0.9","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"7.3","Tissue RNA - basal ganglia [nTPM]":"7.2","Tissue RNA - bone marrow [nTPM]":"1.4","Tissue RNA - breast [nTPM]":"12.3","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"7.3","Tissue RNA - cervix [nTPM]":"21.3","Tissue RNA - choroid plexus [nTPM]":"2.4","Tissue RNA - colon [nTPM]":"24.9","Tissue RNA - duodenum [nTPM]":"19.8","Tissue RNA - endometrium 1 [nTPM]":"17.3","Tissue RNA - epididymis [nTPM]":"4.4","Tissue RNA - esophagus [nTPM]":"13.5","Tissue RNA - fallopian tube [nTPM]":"23.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"13.0","Tissue RNA - hippocampal formation [nTPM]":"4.9","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"41.3","Tissue RNA - liver [nTPM]":"1.4","Tissue RNA - lung [nTPM]":"25.5","Tissue RNA - lymph node [nTPM]":"1.5","Tissue RNA - medulla oblongata [nTPM]":"9.1","Tissue RNA - midbrain [nTPM]":"7.2","Tissue RNA - ovary [nTPM]":"2.3","Tissue RNA - pancreas [nTPM]":"23.3","Tissue RNA - parathyroid gland [nTPM]":"1.7","Tissue RNA - pituitary gland [nTPM]":"4.2","Tissue RNA - placenta [nTPM]":"17.4","Tissue RNA - pons [nTPM]":"8.9","Tissue RNA - prostate [nTPM]":"6.9","Tissue RNA - rectum [nTPM]":"30.0","Tissue RNA - retina [nTPM]":"1.8","Tissue RNA - salivary gland [nTPM]":"8.8","Tissue RNA - seminal vesicle [nTPM]":"8.0","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"10.2","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"4.1","Tissue RNA - spleen [nTPM]":"6.2","Tissue RNA - stomach 1 [nTPM]":"73.3","Tissue RNA - testis [nTPM]":"3.0","Tissue RNA - thalamus [nTPM]":"8.1","Tissue RNA - thymus [nTPM]":"2.0","Tissue RNA - thyroid gland [nTPM]":"5.7","Tissue RNA - tongue [nTPM]":"12.0","Tissue RNA - tonsil [nTPM]":"5.3","Tissue RNA - urinary bladder [nTPM]":"30.4","Tissue RNA - vagina [nTPM]":"7.5","Tissue RNA - white matter [nTPM]":"6.3","Cell RNA - A-431 [nTPM]":"25.8","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.9","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"3.7","Cell RNA - ASC TERT1 [nTPM]":"2.7","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.2","Cell RNA - CACO-2 [nTPM]":"10.7","Cell RNA - CAPAN-2 [nTPM]":"26.1","Cell RNA - Daudi [nTPM]":"0.9","Cell RNA - EFO-21 [nTPM]":"39.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"5.5","Cell RNA - HaCaT [nTPM]":"13.4","Cell RNA - HAP1 [nTPM]":"10.2","Cell RNA - HBEC3-KT [nTPM]":"15.7","Cell RNA - HBF TERT88 [nTPM]":"3.1","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"16.6","Cell RNA - HEL [nTPM]":"16.7","Cell RNA - HeLa [nTPM]":"7.6","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.4","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"5.1","Cell RNA - HSkMC [nTPM]":"5.7","Cell RNA - hTCEpi [nTPM]":"2.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.0","Cell RNA - hTERT-HME1 [nTPM]":"12.1","Cell RNA - hTERT-RPE1 [nTPM]":"12.0","Cell RNA - HUVEC TERT2 [nTPM]":"55.5","Cell RNA - JURKAT [nTPM]":"1.4","Cell RNA - K-562 [nTPM]":"13.0","Cell RNA - Karpas-707 [nTPM]":"1.8","Cell RNA - LHCN-M2 [nTPM]":"10.3","Cell RNA - MCF7 [nTPM]":"9.8","Cell RNA - MOLT-4 [nTPM]":"0.9","Cell RNA - NB-4 [nTPM]":"0.4","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"13.5","Cell RNA - PC-3 [nTPM]":"6.6","Cell RNA - REH [nTPM]":"9.8","Cell RNA - RH-30 [nTPM]":"13.1","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"71.2","Cell RNA - RT4 [nTPM]":"119.6","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"3.1","Cell RNA - SiHa [nTPM]":"1.3","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"0.3","Cell RNA - SuSa [nTPM]":"1.5","Cell RNA - T-47d [nTPM]":"7.1","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"53.4","Cell RNA - U-138 MG [nTPM]":"9.7","Cell RNA - U-2 OS [nTPM]":"6.6","Cell RNA - U-2197 [nTPM]":"2.5","Cell RNA - U-251 MG [nTPM]":"16.9","Cell RNA - U-266\/70 [nTPM]":"1.4","Cell RNA - U-266\/84 [nTPM]":"0.7","Cell RNA - U-698 [nTPM]":"0.9","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"1.0","Cell RNA - WM-115 [nTPM]":"1.6","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"1.6","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"7.2","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"7.3","Brain RNA - hippocampal formation [nTPM]":"4.9","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"9.1","Brain RNA - midbrain [nTPM]":"7.2","Brain RNA - pons [nTPM]":"8.9","Brain RNA - spinal cord [nTPM]":"4.1","Brain RNA - thalamus [nTPM]":"8.1","Brain RNA - white matter [nTPM]":"6.3","Single Cell Type RNA - Adipocytes [nTPM]":"80.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"184.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"33.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"29.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"69.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"125.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"52.8","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"71.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"5.8","Single Cell Type RNA - Endothelial cells [nTPM]":"70.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.9","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"10.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"75.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"4.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"111.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"107.7","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"69.3","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"29.0","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"2.6","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"346.6","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"49.8","Single Cell Type RNA - Paneth cells [nTPM]":"19.3","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"53.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.7","Single Cell Type RNA - Spermatocytes [nTPM]":"3.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"39.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"0.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"53.9","Single Cell Type RNA - Urothelial cells [nTPM]":"45.4"},{"Gene":"MEF2B","Gene synonym":["RSRFR2"],"Ensembl":"ENSG00000213999","Gene description":"Myocyte enhancer factor 2B","Uniprot":["Q02080"],"Chromosome":"19","Position":"19145567-19192131","Protein class":["Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"lymphoid tissue":"39.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Plasma cells":"29.3"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"10","RNA cell line specific nTPM":{"Daudi":"223.4","U-266\/70":"217.6","U-698":"299.5"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004734"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cell Junctions","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA004734":"AB_10963939"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.31e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.44e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.98e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"1.8","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"5.4","Tissue RNA - bone marrow [nTPM]":"2.3","Tissue RNA - breast [nTPM]":"2.6","Tissue RNA - cerebellum [nTPM]":"4.4","Tissue RNA - cerebral cortex [nTPM]":"6.1","Tissue RNA - cervix [nTPM]":"4.0","Tissue RNA - choroid plexus [nTPM]":"4.4","Tissue RNA - colon [nTPM]":"3.1","Tissue RNA - duodenum [nTPM]":"1.8","Tissue RNA - endometrium 1 [nTPM]":"2.3","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"1.4","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"4.5","Tissue RNA - hypothalamus [nTPM]":"4.7","Tissue RNA - kidney [nTPM]":"2.7","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"2.6","Tissue RNA - lymph node [nTPM]":"39.3","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"3.9","Tissue RNA - pancreas [nTPM]":"1.5","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"2.6","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"4.8","Tissue RNA - prostate [nTPM]":"4.5","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"0.9","Tissue RNA - salivary gland [nTPM]":"2.6","Tissue RNA - seminal vesicle [nTPM]":"1.3","Tissue RNA - skeletal muscle [nTPM]":"1.0","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"4.9","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"4.3","Tissue RNA - spleen [nTPM]":"8.8","Tissue RNA - stomach 1 [nTPM]":"2.6","Tissue RNA - testis [nTPM]":"3.2","Tissue RNA - thalamus [nTPM]":"5.2","Tissue RNA - thymus [nTPM]":"1.8","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"31.5","Tissue RNA - urinary bladder [nTPM]":"2.3","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"6.1","Cell RNA - A-431 [nTPM]":"2.3","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"2.1","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"2.5","Cell RNA - BEWO [nTPM]":"2.2","Cell RNA - BJ [nTPM]":"1.3","Cell RNA - BJ hTERT+ [nTPM]":"0.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.2","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"3.2","Cell RNA - Daudi [nTPM]":"223.4","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.9","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"2.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.8","Cell RNA - HBF TERT88 [nTPM]":"0.3","Cell RNA - HDLM-2 [nTPM]":"1.0","Cell RNA - HEK 293 [nTPM]":"5.1","Cell RNA - HEL [nTPM]":"1.4","Cell RNA - HeLa [nTPM]":"0.6","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"2.8","Cell RNA - HL-60 [nTPM]":"1.2","Cell RNA - HMC-1 [nTPM]":"2.0","Cell RNA - HSkMC [nTPM]":"1.0","Cell RNA - hTCEpi [nTPM]":"1.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.1","Cell RNA - hTERT-HME1 [nTPM]":"1.6","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"4.2","Cell RNA - K-562 [nTPM]":"0.9","Cell RNA - Karpas-707 [nTPM]":"3.9","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"3.9","Cell RNA - MOLT-4 [nTPM]":"1.6","Cell RNA - NB-4 [nTPM]":"1.8","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"12.8","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"0.9","Cell RNA - RPMI-8226 [nTPM]":"5.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.5","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.3","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"2.5","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"1.7","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.5","Cell RNA - TIME [nTPM]":"0.7","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"4.0","Cell RNA - U-2197 [nTPM]":"6.9","Cell RNA - U-251 MG [nTPM]":"1.8","Cell RNA - U-266\/70 [nTPM]":"217.6","Cell RNA - U-266\/84 [nTPM]":"24.0","Cell RNA - U-698 [nTPM]":"299.5","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"1.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"5.4","Brain RNA - cerebellum [nTPM]":"4.4","Brain RNA - cerebral cortex [nTPM]":"6.1","Brain RNA - hippocampal formation [nTPM]":"4.5","Brain RNA - hypothalamus [nTPM]":"4.7","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"4.8","Brain RNA - spinal cord [nTPM]":"4.3","Brain RNA - thalamus [nTPM]":"5.2","Brain RNA - white matter [nTPM]":"6.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"29.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MEN1","Gene synonym":[],"Ensembl":"ENSG00000133895","Gene description":"Menin 1","Uniprot":["O00255"],"Chromosome":"11","Position":"64803510-64811294","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030342"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA030342":"AB_10610138"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.78e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.08e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.39e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.31e-5"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.76e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.1","Tissue RNA - adrenal gland [nTPM]":"24.2","Tissue RNA - amygdala [nTPM]":"13.1","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"12.7","Tissue RNA - cerebral cortex [nTPM]":"15.0","Tissue RNA - cervix [nTPM]":"19.3","Tissue RNA - choroid plexus [nTPM]":"13.0","Tissue RNA - colon [nTPM]":"16.8","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"17.4","Tissue RNA - epididymis [nTPM]":"8.1","Tissue RNA - esophagus [nTPM]":"23.9","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"5.5","Tissue RNA - heart muscle [nTPM]":"12.4","Tissue RNA - hippocampal formation [nTPM]":"14.3","Tissue RNA - hypothalamus [nTPM]":"12.7","Tissue RNA - kidney [nTPM]":"19.4","Tissue RNA - liver [nTPM]":"30.3","Tissue RNA - lung [nTPM]":"16.1","Tissue RNA - lymph node [nTPM]":"10.9","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"12.5","Tissue RNA - ovary [nTPM]":"20.8","Tissue RNA - pancreas [nTPM]":"26.2","Tissue RNA - parathyroid gland [nTPM]":"6.3","Tissue RNA - pituitary gland [nTPM]":"21.7","Tissue RNA - placenta [nTPM]":"7.8","Tissue RNA - pons [nTPM]":"12.6","Tissue RNA - prostate [nTPM]":"20.2","Tissue RNA - rectum [nTPM]":"4.7","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"21.3","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"11.0","Tissue RNA - skin 1 [nTPM]":"24.0","Tissue RNA - small intestine [nTPM]":"20.9","Tissue RNA - smooth muscle [nTPM]":"5.3","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"25.5","Tissue RNA - stomach 1 [nTPM]":"20.6","Tissue RNA - testis [nTPM]":"16.3","Tissue RNA - thalamus [nTPM]":"13.5","Tissue RNA - thymus [nTPM]":"17.1","Tissue RNA - thyroid gland [nTPM]":"24.5","Tissue RNA - tongue [nTPM]":"5.8","Tissue RNA - tonsil [nTPM]":"10.2","Tissue RNA - urinary bladder [nTPM]":"16.4","Tissue RNA - vagina [nTPM]":"18.7","Tissue RNA - white matter [nTPM]":"12.9","Cell RNA - A-431 [nTPM]":"30.8","Cell RNA - A549 [nTPM]":"33.7","Cell RNA - AF22 [nTPM]":"22.4","Cell RNA - AN3-CA [nTPM]":"37.7","Cell RNA - ASC diff [nTPM]":"30.4","Cell RNA - ASC TERT1 [nTPM]":"17.4","Cell RNA - BEWO [nTPM]":"24.8","Cell RNA - BJ [nTPM]":"19.2","Cell RNA - BJ hTERT+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"35.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.2","Cell RNA - CACO-2 [nTPM]":"19.0","Cell RNA - CAPAN-2 [nTPM]":"25.5","Cell RNA - Daudi [nTPM]":"43.6","Cell RNA - EFO-21 [nTPM]":"33.8","Cell RNA - fHDF\/TERT166 [nTPM]":"16.7","Cell RNA - GAMG [nTPM]":"29.8","Cell RNA - HaCaT [nTPM]":"39.0","Cell RNA - HAP1 [nTPM]":"36.4","Cell RNA - HBEC3-KT [nTPM]":"28.3","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"30.5","Cell RNA - HEK 293 [nTPM]":"48.1","Cell RNA - HEL [nTPM]":"35.6","Cell RNA - HeLa [nTPM]":"17.3","Cell RNA - Hep G2 [nTPM]":"30.9","Cell RNA - HHSteC [nTPM]":"27.2","Cell RNA - HL-60 [nTPM]":"23.6","Cell RNA - HMC-1 [nTPM]":"22.8","Cell RNA - HSkMC [nTPM]":"19.2","Cell RNA - hTCEpi [nTPM]":"18.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"26.8","Cell RNA - hTERT-HME1 [nTPM]":"21.9","Cell RNA - hTERT-RPE1 [nTPM]":"16.5","Cell RNA - HUVEC TERT2 [nTPM]":"33.7","Cell RNA - JURKAT [nTPM]":"49.3","Cell RNA - K-562 [nTPM]":"51.5","Cell RNA - Karpas-707 [nTPM]":"15.7","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"54.2","Cell RNA - MOLT-4 [nTPM]":"60.3","Cell RNA - NB-4 [nTPM]":"29.3","Cell RNA - NTERA-2 [nTPM]":"36.7","Cell RNA - OE19 [nTPM]":"30.3","Cell RNA - PC-3 [nTPM]":"54.7","Cell RNA - REH [nTPM]":"45.1","Cell RNA - RH-30 [nTPM]":"29.8","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"23.2","Cell RNA - RT4 [nTPM]":"22.8","Cell RNA - SCLC-21H [nTPM]":"33.6","Cell RNA - SH-SY5Y [nTPM]":"28.9","Cell RNA - SiHa [nTPM]":"26.0","Cell RNA - SK-BR-3 [nTPM]":"36.9","Cell RNA - SK-MEL-30 [nTPM]":"27.9","Cell RNA - SuSa [nTPM]":"16.5","Cell RNA - T-47d [nTPM]":"56.6","Cell RNA - THP-1 [nTPM]":"27.1","Cell RNA - TIME [nTPM]":"17.4","Cell RNA - U-138 MG [nTPM]":"23.5","Cell RNA - U-2 OS [nTPM]":"28.8","Cell RNA - U-2197 [nTPM]":"36.5","Cell RNA - U-251 MG [nTPM]":"16.7","Cell RNA - U-266\/70 [nTPM]":"21.8","Cell RNA - U-266\/84 [nTPM]":"30.4","Cell RNA - U-698 [nTPM]":"22.1","Cell RNA - U-87 MG [nTPM]":"25.5","Cell RNA - U-937 [nTPM]":"16.2","Cell RNA - WM-115 [nTPM]":"21.0","Blood RNA - basophil [nTPM]":"0.5","Blood RNA - classical monocyte [nTPM]":"0.5","Blood RNA - eosinophil [nTPM]":"1.4","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"1.8","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"1.9","Blood RNA - myeloid DC [nTPM]":"0.6","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"0.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.9","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"0.9","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"13.1","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"12.7","Brain RNA - cerebral cortex [nTPM]":"15.0","Brain RNA - hippocampal formation [nTPM]":"14.3","Brain RNA - hypothalamus [nTPM]":"12.7","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"12.5","Brain RNA - pons [nTPM]":"12.6","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.5","Brain RNA - white matter [nTPM]":"12.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"10.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"4.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"5.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"8.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"2.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - dendritic cells [nTPM]":"8.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.9","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.0","Single Cell Type RNA - Endothelial cells [nTPM]":"7.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"10.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.7","Single Cell Type RNA - Fibroblasts [nTPM]":"6.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"14.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"10.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.0","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"3.1","Single Cell Type RNA - Langerhans cells [nTPM]":"2.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"12.2","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"6.3","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"5.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.5","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"3.8","Single Cell Type RNA - Plasma cells [nTPM]":"8.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.6","Single Cell Type RNA - Spermatocytes [nTPM]":"14.2","Single Cell Type RNA - Spermatogonia [nTPM]":"13.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.3","Single Cell Type RNA - T-cells [nTPM]":"8.9","Single Cell Type RNA - Theca cells [nTPM]":"14.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"3.3"},{"Gene":"MET","Gene synonym":["DFNB97","HGFR","RCCP2"],"Ensembl":"ENSG00000105976","Gene description":"MET proto-oncogene, receptor tyrosine kinase","Uniprot":["P08581"],"Chromosome":"7","Position":"116672196-116798377","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant","FDA approved drug targets","Non-syndromic deafness","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"42.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 2":"103.6","Club cells":"99.8","Glandular and luminal cells":"161.4","Pancreatic endocrine cells":"93.9","Prostatic glandular cells":"149.3","Urothelial cells":"128.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"5","RNA brain regional specific nTPM":{"cerebral cortex":"7.5","hippocampal formation":"6.6","midbrain":"2.5","pons":"4.9","white matter":"7.8"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"203.8","CAPAN-2":"219.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005282","CAB018577","HPA055607"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":179000000,"Blood concentration - Conc. blood MS [pg\/L]":"100000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 86: Liver & Placenta - Transport via ER","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB005282":"AB_631940","CAB018577":"AB_649068","HPA055607":"AB_2682860"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.71e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.81e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.21e-7"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.53e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-1"},"Tissue RNA - adipose tissue [nTPM]":"10.3","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"0.6","Tissue RNA - bone marrow [nTPM]":"7.4","Tissue RNA - breast [nTPM]":"8.9","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"13.1","Tissue RNA - choroid plexus [nTPM]":"9.6","Tissue RNA - colon [nTPM]":"9.7","Tissue RNA - duodenum [nTPM]":"6.5","Tissue RNA - endometrium 1 [nTPM]":"6.4","Tissue RNA - epididymis [nTPM]":"2.5","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"11.9","Tissue RNA - heart muscle [nTPM]":"6.2","Tissue RNA - hippocampal formation [nTPM]":"6.6","Tissue RNA - hypothalamus [nTPM]":"0.8","Tissue RNA - kidney [nTPM]":"20.1","Tissue RNA - liver [nTPM]":"42.9","Tissue RNA - lung [nTPM]":"20.3","Tissue RNA - lymph node [nTPM]":"2.3","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"2.5","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"6.6","Tissue RNA - parathyroid gland [nTPM]":"0.8","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"26.4","Tissue RNA - pons [nTPM]":"4.9","Tissue RNA - prostate [nTPM]":"6.7","Tissue RNA - rectum [nTPM]":"9.3","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"8.7","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"14.3","Tissue RNA - skin 1 [nTPM]":"7.7","Tissue RNA - small intestine [nTPM]":"8.2","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"0.3","Tissue RNA - spleen [nTPM]":"6.0","Tissue RNA - stomach 1 [nTPM]":"15.4","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.5","Tissue RNA - thymus [nTPM]":"3.7","Tissue RNA - thyroid gland [nTPM]":"17.6","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"3.2","Tissue RNA - urinary bladder [nTPM]":"18.4","Tissue RNA - vagina [nTPM]":"4.4","Tissue RNA - white matter [nTPM]":"7.8","Cell RNA - A-431 [nTPM]":"203.8","Cell RNA - A549 [nTPM]":"115.3","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.6","Cell RNA - ASC diff [nTPM]":"8.6","Cell RNA - ASC TERT1 [nTPM]":"8.7","Cell RNA - BEWO [nTPM]":"7.9","Cell RNA - BJ [nTPM]":"113.7","Cell RNA - BJ hTERT+ [nTPM]":"48.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"51.1","Cell RNA - CACO-2 [nTPM]":"25.0","Cell RNA - CAPAN-2 [nTPM]":"219.0","Cell RNA - Daudi [nTPM]":"8.4","Cell RNA - EFO-21 [nTPM]":"179.0","Cell RNA - fHDF\/TERT166 [nTPM]":"72.1","Cell RNA - GAMG [nTPM]":"163.3","Cell RNA - HaCaT [nTPM]":"51.8","Cell RNA - HAP1 [nTPM]":"19.7","Cell RNA - HBEC3-KT [nTPM]":"110.0","Cell RNA - HBF TERT88 [nTPM]":"123.7","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"23.4","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"112.5","Cell RNA - Hep G2 [nTPM]":"21.4","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"11.4","Cell RNA - hTCEpi [nTPM]":"42.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"40.6","Cell RNA - hTERT-HME1 [nTPM]":"129.1","Cell RNA - hTERT-RPE1 [nTPM]":"109.4","Cell RNA - HUVEC TERT2 [nTPM]":"42.4","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"4.5","Cell RNA - Karpas-707 [nTPM]":"0.8","Cell RNA - LHCN-M2 [nTPM]":"114.1","Cell RNA - MCF7 [nTPM]":"5.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"17.3","Cell RNA - OE19 [nTPM]":"32.9","Cell RNA - PC-3 [nTPM]":"113.0","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"95.3","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"105.8","Cell RNA - RT4 [nTPM]":"24.0","Cell RNA - SCLC-21H [nTPM]":"16.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"45.4","Cell RNA - SK-BR-3 [nTPM]":"15.4","Cell RNA - SK-MEL-30 [nTPM]":"44.9","Cell RNA - SuSa [nTPM]":"19.8","Cell RNA - T-47d [nTPM]":"0.4","Cell RNA - THP-1 [nTPM]":"0.9","Cell RNA - TIME [nTPM]":"72.3","Cell RNA - U-138 MG [nTPM]":"89.7","Cell RNA - U-2 OS [nTPM]":"30.6","Cell RNA - U-2197 [nTPM]":"46.7","Cell RNA - U-251 MG [nTPM]":"88.9","Cell RNA - U-266\/70 [nTPM]":"2.5","Cell RNA - U-266\/84 [nTPM]":"19.1","Cell RNA - U-698 [nTPM]":"1.5","Cell RNA - U-87 MG [nTPM]":"99.3","Cell RNA - U-937 [nTPM]":"0.3","Cell RNA - WM-115 [nTPM]":"12.9","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.6","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.6","Brain RNA - hypothalamus [nTPM]":"0.8","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"2.5","Brain RNA - pons [nTPM]":"4.9","Brain RNA - spinal cord [nTPM]":"0.3","Brain RNA - thalamus [nTPM]":"0.5","Brain RNA - white matter [nTPM]":"7.8","Single Cell Type RNA - Adipocytes [nTPM]":"32.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"103.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"1.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"39.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"70.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"58.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"38.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"99.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"76.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"20.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"38.5","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"52.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.6","Single Cell Type RNA - Endothelial cells [nTPM]":"20.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"46.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"161.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"30.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.5","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"2.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"4.4","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"1.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"93.9","Single Cell Type RNA - Paneth cells [nTPM]":"5.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"149.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"11.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"37.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"21.8","Single Cell Type RNA - T-cells [nTPM]":"1.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.4","Single Cell Type RNA - Urothelial cells [nTPM]":"128.6"},{"Gene":"MITF","Gene synonym":["bHLHe32","MI","WS2","WS2A"],"Ensembl":"ENSG00000187098","Gene description":"Melanocyte inducing transcription factor","Uniprot":["O75030"],"Chromosome":"3","Position":"69739464-69968336","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Albinism","Cancer-related genes","Deafness","Disease variant","Microphthalmia","Osteopetrosis","Waardenburg syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Inhibitory neurons":"133.5","Melanocytes":"585.2","Oligodendrocyte precursor cells":"166.9","Oligodendrocytes":"240.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"melanoma":"39.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"5.2","classical monocyte":"9.4","intermediate monocyte":"3.3","myeloid DC":"6.1","non-classical monocyte":"5.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"6","RNA blood lineage specific nTPM":{"dendritic cells":"6.1","granulocytes":"5.2","monocytes":"9.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HMC-1":"89.1","SK-MEL-30":"254.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002578","HPA003259"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002578":"AB_564111","HPA003259":"AB_1079381"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.26e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.04e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.31e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.87e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.35e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.73e-1"},"Tissue RNA - adipose tissue [nTPM]":"13.8","Tissue RNA - adrenal gland [nTPM]":"4.4","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"3.8","Tissue RNA - basal ganglia [nTPM]":"9.2","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"10.0","Tissue RNA - cerebellum [nTPM]":"9.4","Tissue RNA - cerebral cortex [nTPM]":"6.3","Tissue RNA - cervix [nTPM]":"51.3","Tissue RNA - choroid plexus [nTPM]":"21.2","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"2.8","Tissue RNA - endometrium 1 [nTPM]":"46.2","Tissue RNA - epididymis [nTPM]":"4.5","Tissue RNA - esophagus [nTPM]":"8.9","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"16.8","Tissue RNA - heart muscle [nTPM]":"31.1","Tissue RNA - hippocampal formation [nTPM]":"5.2","Tissue RNA - hypothalamus [nTPM]":"9.3","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"9.7","Tissue RNA - lymph node [nTPM]":"3.4","Tissue RNA - medulla oblongata [nTPM]":"12.5","Tissue RNA - midbrain [nTPM]":"9.5","Tissue RNA - ovary [nTPM]":"18.7","Tissue RNA - pancreas [nTPM]":"4.2","Tissue RNA - parathyroid gland [nTPM]":"16.8","Tissue RNA - pituitary gland [nTPM]":"3.8","Tissue RNA - placenta [nTPM]":"3.3","Tissue RNA - pons [nTPM]":"10.4","Tissue RNA - prostate [nTPM]":"8.4","Tissue RNA - rectum [nTPM]":"4.5","Tissue RNA - retina [nTPM]":"1.2","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"50.6","Tissue RNA - skin 1 [nTPM]":"11.0","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"46.0","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"2.0","Tissue RNA - stomach 1 [nTPM]":"9.4","Tissue RNA - testis [nTPM]":"2.3","Tissue RNA - thalamus [nTPM]":"10.3","Tissue RNA - thymus [nTPM]":"2.2","Tissue RNA - thyroid gland [nTPM]":"7.6","Tissue RNA - tongue [nTPM]":"43.3","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"10.6","Tissue RNA - vagina [nTPM]":"16.6","Tissue RNA - white matter [nTPM]":"13.8","Cell RNA - A-431 [nTPM]":"17.2","Cell RNA - A549 [nTPM]":"12.2","Cell RNA - AF22 [nTPM]":"1.3","Cell RNA - AN3-CA [nTPM]":"5.1","Cell RNA - ASC diff [nTPM]":"18.8","Cell RNA - ASC TERT1 [nTPM]":"0.3","Cell RNA - BEWO [nTPM]":"2.0","Cell RNA - BJ [nTPM]":"16.9","Cell RNA - BJ hTERT+ [nTPM]":"9.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"7.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.8","Cell RNA - CACO-2 [nTPM]":"6.1","Cell RNA - CAPAN-2 [nTPM]":"0.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"21.6","Cell RNA - HaCaT [nTPM]":"8.6","Cell RNA - HAP1 [nTPM]":"3.7","Cell RNA - HBEC3-KT [nTPM]":"9.4","Cell RNA - HBF TERT88 [nTPM]":"8.6","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"37.1","Cell RNA - HeLa [nTPM]":"24.5","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"4.5","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"89.1","Cell RNA - HSkMC [nTPM]":"15.3","Cell RNA - hTCEpi [nTPM]":"3.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"8.6","Cell RNA - hTERT-RPE1 [nTPM]":"29.1","Cell RNA - HUVEC TERT2 [nTPM]":"2.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"12.3","Cell RNA - Karpas-707 [nTPM]":"5.2","Cell RNA - LHCN-M2 [nTPM]":"5.4","Cell RNA - MCF7 [nTPM]":"1.2","Cell RNA - MOLT-4 [nTPM]":"0.7","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"0.7","Cell RNA - PC-3 [nTPM]":"8.3","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"1.9","Cell RNA - RPMI-8226 [nTPM]":"7.7","Cell RNA - RPTEC TERT1 [nTPM]":"45.2","Cell RNA - RT4 [nTPM]":"9.0","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"1.9","Cell RNA - SiHa [nTPM]":"8.8","Cell RNA - SK-BR-3 [nTPM]":"3.1","Cell RNA - SK-MEL-30 [nTPM]":"254.1","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"2.3","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"3.8","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"5.1","Cell RNA - U-251 MG [nTPM]":"3.5","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"1.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"7.7","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"9.2","Blood RNA - basophil [nTPM]":"5.2","Blood RNA - classical monocyte [nTPM]":"9.4","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"3.3","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.1","Blood RNA - myeloid DC [nTPM]":"6.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"5.9","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"3.1","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"9.2","Brain RNA - cerebellum [nTPM]":"9.4","Brain RNA - cerebral cortex [nTPM]":"6.3","Brain RNA - hippocampal formation [nTPM]":"5.2","Brain RNA - hypothalamus [nTPM]":"9.3","Brain RNA - medulla oblongata [nTPM]":"12.5","Brain RNA - midbrain [nTPM]":"9.5","Brain RNA - pons [nTPM]":"10.4","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"10.3","Brain RNA - white matter [nTPM]":"13.8","Single Cell Type RNA - Adipocytes [nTPM]":"4.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.8","Single Cell Type RNA - Astrocytes [nTPM]":"34.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"42.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"3.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"1.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"109.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"11.5","Single Cell Type RNA - Club cells [nTPM]":"18.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"50.9","Single Cell Type RNA - Ductal cells [nTPM]":"14.7","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"94.3","Single Cell Type RNA - Endothelial cells [nTPM]":"7.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"8.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.0","Single Cell Type RNA - Fibroblasts [nTPM]":"38.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"71.2","Single Cell Type RNA - granulocytes [nTPM]":"106.8","Single Cell Type RNA - Granulosa cells [nTPM]":"10.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.8","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"133.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"30.8","Single Cell Type RNA - Langerhans cells [nTPM]":"30.9","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"44.4","Single Cell Type RNA - Macrophages [nTPM]":"24.3","Single Cell Type RNA - Melanocytes [nTPM]":"585.2","Single Cell Type RNA - Microglial cells [nTPM]":"50.6","Single Cell Type RNA - monocytes [nTPM]":"10.6","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"166.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"240.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"50.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"24.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.6","Single Cell Type RNA - Spermatocytes [nTPM]":"4.0","Single Cell Type RNA - Spermatogonia [nTPM]":"6.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"18.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"3.8","Single Cell Type RNA - Theca cells [nTPM]":"5.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"7.1"},{"Gene":"MLH1","Gene synonym":["COCA2","FCC2","HNPCC","HNPCC2"],"Ensembl":"ENSG00000076242","Gene description":"MutL homolog 1","Uniprot":["P40692"],"Chromosome":"3","Position":"36993350-37050846","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","DNA damage","DNA repair"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013294","HPA052707","HPA060714","CAB070868"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB013294":"AB_2533406","CAB070868":null,"HPA052707":"AB_2681923","HPA060714":"AB_2684348"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.24e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.54e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.86e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"7.3","Tissue RNA - appendix [nTPM]":"17.4","Tissue RNA - basal ganglia [nTPM]":"8.0","Tissue RNA - bone marrow [nTPM]":"22.1","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"7.1","Tissue RNA - cerebral cortex [nTPM]":"9.1","Tissue RNA - cervix [nTPM]":"17.4","Tissue RNA - choroid plexus [nTPM]":"7.6","Tissue RNA - colon [nTPM]":"17.4","Tissue RNA - duodenum [nTPM]":"12.0","Tissue RNA - endometrium 1 [nTPM]":"16.3","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"14.3","Tissue RNA - fallopian tube [nTPM]":"14.9","Tissue RNA - gallbladder [nTPM]":"11.1","Tissue RNA - heart muscle [nTPM]":"35.4","Tissue RNA - hippocampal formation [nTPM]":"6.9","Tissue RNA - hypothalamus [nTPM]":"8.3","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"15.8","Tissue RNA - lymph node [nTPM]":"21.9","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"7.4","Tissue RNA - ovary [nTPM]":"15.1","Tissue RNA - pancreas [nTPM]":"16.6","Tissue RNA - parathyroid gland [nTPM]":"22.4","Tissue RNA - pituitary gland [nTPM]":"22.7","Tissue RNA - placenta [nTPM]":"14.8","Tissue RNA - pons [nTPM]":"7.6","Tissue RNA - prostate [nTPM]":"16.2","Tissue RNA - rectum [nTPM]":"14.5","Tissue RNA - retina [nTPM]":"9.6","Tissue RNA - salivary gland [nTPM]":"12.1","Tissue RNA - seminal vesicle [nTPM]":"14.0","Tissue RNA - skeletal muscle [nTPM]":"49.1","Tissue RNA - skin 1 [nTPM]":"13.4","Tissue RNA - small intestine [nTPM]":"13.4","Tissue RNA - smooth muscle [nTPM]":"19.2","Tissue RNA - spinal cord [nTPM]":"7.1","Tissue RNA - spleen [nTPM]":"18.8","Tissue RNA - stomach 1 [nTPM]":"15.5","Tissue RNA - testis [nTPM]":"25.4","Tissue RNA - thalamus [nTPM]":"7.7","Tissue RNA - thymus [nTPM]":"28.4","Tissue RNA - thyroid gland [nTPM]":"19.2","Tissue RNA - tongue [nTPM]":"42.2","Tissue RNA - tonsil [nTPM]":"24.3","Tissue RNA - urinary bladder [nTPM]":"17.2","Tissue RNA - vagina [nTPM]":"14.0","Tissue RNA - white matter [nTPM]":"9.0","Cell RNA - A-431 [nTPM]":"37.1","Cell RNA - A549 [nTPM]":"56.7","Cell RNA - AF22 [nTPM]":"66.7","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"25.9","Cell RNA - ASC TERT1 [nTPM]":"34.5","Cell RNA - BEWO [nTPM]":"30.7","Cell RNA - BJ [nTPM]":"54.7","Cell RNA - BJ hTERT+ [nTPM]":"44.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"64.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"62.3","Cell RNA - CACO-2 [nTPM]":"43.4","Cell RNA - CAPAN-2 [nTPM]":"40.1","Cell RNA - Daudi [nTPM]":"92.2","Cell RNA - EFO-21 [nTPM]":"25.0","Cell RNA - fHDF\/TERT166 [nTPM]":"44.1","Cell RNA - GAMG [nTPM]":"33.6","Cell RNA - HaCaT [nTPM]":"24.7","Cell RNA - HAP1 [nTPM]":"65.2","Cell RNA - HBEC3-KT [nTPM]":"45.8","Cell RNA - HBF TERT88 [nTPM]":"68.5","Cell RNA - HDLM-2 [nTPM]":"42.2","Cell RNA - HEK 293 [nTPM]":"32.1","Cell RNA - HEL [nTPM]":"68.1","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"54.9","Cell RNA - HHSteC [nTPM]":"23.2","Cell RNA - HL-60 [nTPM]":"81.9","Cell RNA - HMC-1 [nTPM]":"40.5","Cell RNA - HSkMC [nTPM]":"28.4","Cell RNA - hTCEpi [nTPM]":"29.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"54.8","Cell RNA - hTERT-HME1 [nTPM]":"57.8","Cell RNA - hTERT-RPE1 [nTPM]":"21.9","Cell RNA - HUVEC TERT2 [nTPM]":"37.6","Cell RNA - JURKAT [nTPM]":"55.0","Cell RNA - K-562 [nTPM]":"86.0","Cell RNA - Karpas-707 [nTPM]":"32.0","Cell RNA - LHCN-M2 [nTPM]":"66.2","Cell RNA - MCF7 [nTPM]":"27.6","Cell RNA - MOLT-4 [nTPM]":"81.0","Cell RNA - NB-4 [nTPM]":"22.2","Cell RNA - NTERA-2 [nTPM]":"49.4","Cell RNA - OE19 [nTPM]":"38.4","Cell RNA - PC-3 [nTPM]":"31.6","Cell RNA - REH [nTPM]":"4.6","Cell RNA - RH-30 [nTPM]":"90.6","Cell RNA - RPMI-8226 [nTPM]":"40.2","Cell RNA - RPTEC TERT1 [nTPM]":"35.1","Cell RNA - RT4 [nTPM]":"39.3","Cell RNA - SCLC-21H [nTPM]":"14.2","Cell RNA - SH-SY5Y [nTPM]":"36.1","Cell RNA - SiHa [nTPM]":"52.1","Cell RNA - SK-BR-3 [nTPM]":"56.9","Cell RNA - SK-MEL-30 [nTPM]":"32.7","Cell RNA - SuSa [nTPM]":"33.3","Cell RNA - T-47d [nTPM]":"79.9","Cell RNA - THP-1 [nTPM]":"55.6","Cell RNA - TIME [nTPM]":"28.8","Cell RNA - U-138 MG [nTPM]":"46.0","Cell RNA - U-2 OS [nTPM]":"50.5","Cell RNA - U-2197 [nTPM]":"44.0","Cell RNA - U-251 MG [nTPM]":"65.9","Cell RNA - U-266\/70 [nTPM]":"29.1","Cell RNA - U-266\/84 [nTPM]":"93.7","Cell RNA - U-698 [nTPM]":"88.1","Cell RNA - U-87 MG [nTPM]":"37.8","Cell RNA - U-937 [nTPM]":"71.9","Cell RNA - WM-115 [nTPM]":"45.7","Blood RNA - basophil [nTPM]":"12.6","Blood RNA - classical monocyte [nTPM]":"12.5","Blood RNA - eosinophil [nTPM]":"15.1","Blood RNA - gdT-cell [nTPM]":"12.7","Blood RNA - intermediate monocyte [nTPM]":"22.6","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"11.3","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"11.4","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"9.7","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"9.6","Blood RNA - neutrophil [nTPM]":"2.6","Blood RNA - NK-cell [nTPM]":"7.8","Blood RNA - non-classical monocyte [nTPM]":"29.2","Blood RNA - plasmacytoid DC [nTPM]":"5.9","Blood RNA - T-reg [nTPM]":"15.0","Blood RNA - total PBMC [nTPM]":"11.0","Brain RNA - amygdala [nTPM]":"7.3","Brain RNA - basal ganglia [nTPM]":"8.0","Brain RNA - cerebellum [nTPM]":"7.1","Brain RNA - cerebral cortex [nTPM]":"9.1","Brain RNA - hippocampal formation [nTPM]":"6.9","Brain RNA - hypothalamus [nTPM]":"8.3","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"7.4","Brain RNA - pons [nTPM]":"7.6","Brain RNA - spinal cord [nTPM]":"7.1","Brain RNA - thalamus [nTPM]":"7.7","Brain RNA - white matter [nTPM]":"9.0","Single Cell Type RNA - Adipocytes [nTPM]":"10.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.8","Single Cell Type RNA - Astrocytes [nTPM]":"22.9","Single Cell Type RNA - B-cells [nTPM]":"18.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"7.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"18.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"18.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"41.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"33.4","Single Cell Type RNA - dendritic cells [nTPM]":"16.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"31.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"10.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"5.4","Single Cell Type RNA - Erythroid cells [nTPM]":"19.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"18.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.9","Single Cell Type RNA - Fibroblasts [nTPM]":"14.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.5","Single Cell Type RNA - granulocytes [nTPM]":"7.6","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"14.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"20.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"21.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"16.3","Single Cell Type RNA - Langerhans cells [nTPM]":"8.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.2","Single Cell Type RNA - Leydig cells [nTPM]":"11.1","Single Cell Type RNA - Macrophages [nTPM]":"13.8","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"15.9","Single Cell Type RNA - NK-cells [nTPM]":"11.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"27.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"31.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"22.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"10.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.0","Single Cell Type RNA - Spermatocytes [nTPM]":"58.6","Single Cell Type RNA - Spermatogonia [nTPM]":"29.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"5.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"20.0","Single Cell Type RNA - T-cells [nTPM]":"15.9","Single Cell Type RNA - Theca cells [nTPM]":"14.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.4","Single Cell Type RNA - Urothelial cells [nTPM]":"6.5"},{"Gene":"MLLT10","Gene synonym":["AF10"],"Ensembl":"ENSG00000078403","Gene description":"MLLT10 histone lysine methyltransferase DOT1L cofactor","Uniprot":["P55197"],"Chromosome":"10","Position":"21524646-21743630","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"93.0"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"201.3","Spermatocytes":"233.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA005736","HPA005747","HPA072790"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 23: Testis - Cell cycle regulation","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 66: Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA005736":null,"HPA005747":"AB_1079393","HPA072790":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.58e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.32e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.75e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.56e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Tissue RNA - adipose tissue [nTPM]":"15.6","Tissue RNA - adrenal gland [nTPM]":"13.0","Tissue RNA - amygdala [nTPM]":"11.9","Tissue RNA - appendix [nTPM]":"12.0","Tissue RNA - basal ganglia [nTPM]":"13.6","Tissue RNA - bone marrow [nTPM]":"30.5","Tissue RNA - breast [nTPM]":"14.4","Tissue RNA - cerebellum [nTPM]":"21.5","Tissue RNA - cerebral cortex [nTPM]":"16.0","Tissue RNA - cervix [nTPM]":"18.2","Tissue RNA - choroid plexus [nTPM]":"16.6","Tissue RNA - colon [nTPM]":"20.8","Tissue RNA - duodenum [nTPM]":"9.1","Tissue RNA - endometrium 1 [nTPM]":"18.7","Tissue RNA - epididymis [nTPM]":"16.0","Tissue RNA - esophagus [nTPM]":"16.1","Tissue RNA - fallopian tube [nTPM]":"17.4","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"17.1","Tissue RNA - hippocampal formation [nTPM]":"11.5","Tissue RNA - hypothalamus [nTPM]":"15.2","Tissue RNA - kidney [nTPM]":"15.1","Tissue RNA - liver [nTPM]":"15.6","Tissue RNA - lung [nTPM]":"14.6","Tissue RNA - lymph node [nTPM]":"15.3","Tissue RNA - medulla oblongata [nTPM]":"14.6","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"24.7","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"18.6","Tissue RNA - pituitary gland [nTPM]":"12.6","Tissue RNA - placenta [nTPM]":"16.4","Tissue RNA - pons [nTPM]":"14.1","Tissue RNA - prostate [nTPM]":"13.0","Tissue RNA - rectum [nTPM]":"12.7","Tissue RNA - retina [nTPM]":"20.6","Tissue RNA - salivary gland [nTPM]":"13.7","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"15.6","Tissue RNA - skin 1 [nTPM]":"25.4","Tissue RNA - small intestine [nTPM]":"13.2","Tissue RNA - smooth muscle [nTPM]":"16.8","Tissue RNA - spinal cord [nTPM]":"11.9","Tissue RNA - spleen [nTPM]":"12.8","Tissue RNA - stomach 1 [nTPM]":"12.3","Tissue RNA - testis [nTPM]":"93.0","Tissue RNA - thalamus [nTPM]":"13.7","Tissue RNA - thymus [nTPM]":"23.2","Tissue RNA - thyroid gland [nTPM]":"21.8","Tissue RNA - tongue [nTPM]":"14.2","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"19.1","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"18.6","Cell RNA - A-431 [nTPM]":"32.1","Cell RNA - A549 [nTPM]":"29.6","Cell RNA - AF22 [nTPM]":"38.3","Cell RNA - AN3-CA [nTPM]":"22.2","Cell RNA - ASC diff [nTPM]":"23.3","Cell RNA - ASC TERT1 [nTPM]":"25.0","Cell RNA - BEWO [nTPM]":"44.1","Cell RNA - BJ [nTPM]":"19.6","Cell RNA - BJ hTERT+ [nTPM]":"10.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.6","Cell RNA - CACO-2 [nTPM]":"29.5","Cell RNA - CAPAN-2 [nTPM]":"31.3","Cell RNA - Daudi [nTPM]":"34.9","Cell RNA - EFO-21 [nTPM]":"10.8","Cell RNA - fHDF\/TERT166 [nTPM]":"20.7","Cell RNA - GAMG [nTPM]":"21.1","Cell RNA - HaCaT [nTPM]":"24.1","Cell RNA - HAP1 [nTPM]":"43.3","Cell RNA - HBEC3-KT [nTPM]":"25.1","Cell RNA - HBF TERT88 [nTPM]":"22.2","Cell RNA - HDLM-2 [nTPM]":"25.0","Cell RNA - HEK 293 [nTPM]":"21.9","Cell RNA - HEL [nTPM]":"59.2","Cell RNA - HeLa [nTPM]":"24.5","Cell RNA - Hep G2 [nTPM]":"44.5","Cell RNA - HHSteC [nTPM]":"29.6","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"33.4","Cell RNA - HSkMC [nTPM]":"21.3","Cell RNA - hTCEpi [nTPM]":"28.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"17.7","Cell RNA - hTERT-HME1 [nTPM]":"19.2","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"30.1","Cell RNA - JURKAT [nTPM]":"34.3","Cell RNA - K-562 [nTPM]":"65.4","Cell RNA - Karpas-707 [nTPM]":"26.5","Cell RNA - LHCN-M2 [nTPM]":"19.3","Cell RNA - MCF7 [nTPM]":"28.1","Cell RNA - MOLT-4 [nTPM]":"44.1","Cell RNA - NB-4 [nTPM]":"28.5","Cell RNA - NTERA-2 [nTPM]":"17.3","Cell RNA - OE19 [nTPM]":"17.5","Cell RNA - PC-3 [nTPM]":"9.2","Cell RNA - REH [nTPM]":"36.6","Cell RNA - RH-30 [nTPM]":"23.5","Cell RNA - RPMI-8226 [nTPM]":"31.7","Cell RNA - RPTEC TERT1 [nTPM]":"23.2","Cell RNA - RT4 [nTPM]":"12.6","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"39.6","Cell RNA - SiHa [nTPM]":"24.7","Cell RNA - SK-BR-3 [nTPM]":"29.0","Cell RNA - SK-MEL-30 [nTPM]":"45.8","Cell RNA - SuSa [nTPM]":"30.7","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"37.1","Cell RNA - TIME [nTPM]":"29.8","Cell RNA - U-138 MG [nTPM]":"14.7","Cell RNA - U-2 OS [nTPM]":"24.6","Cell RNA - U-2197 [nTPM]":"26.7","Cell RNA - U-251 MG [nTPM]":"18.9","Cell RNA - U-266\/70 [nTPM]":"23.5","Cell RNA - U-266\/84 [nTPM]":"32.2","Cell RNA - U-698 [nTPM]":"43.4","Cell RNA - U-87 MG [nTPM]":"15.4","Cell RNA - U-937 [nTPM]":"21.5","Cell RNA - WM-115 [nTPM]":"9.9","Blood RNA - basophil [nTPM]":"10.3","Blood RNA - classical monocyte [nTPM]":"6.5","Blood RNA - eosinophil [nTPM]":"13.5","Blood RNA - gdT-cell [nTPM]":"5.0","Blood RNA - intermediate monocyte [nTPM]":"4.1","Blood RNA - MAIT T-cell [nTPM]":"4.6","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"6.1","Blood RNA - memory CD8 T-cell [nTPM]":"6.1","Blood RNA - myeloid DC [nTPM]":"5.1","Blood RNA - naive B-cell [nTPM]":"4.3","Blood RNA - naive CD4 T-cell [nTPM]":"6.6","Blood RNA - naive CD8 T-cell [nTPM]":"6.0","Blood RNA - neutrophil [nTPM]":"4.8","Blood RNA - NK-cell [nTPM]":"4.6","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"7.5","Blood RNA - T-reg [nTPM]":"5.5","Blood RNA - total PBMC [nTPM]":"2.5","Brain RNA - amygdala [nTPM]":"11.9","Brain RNA - basal ganglia [nTPM]":"13.6","Brain RNA - cerebellum [nTPM]":"21.5","Brain RNA - cerebral cortex [nTPM]":"16.0","Brain RNA - hippocampal formation [nTPM]":"11.5","Brain RNA - hypothalamus [nTPM]":"15.2","Brain RNA - medulla oblongata [nTPM]":"14.6","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"14.1","Brain RNA - spinal cord [nTPM]":"11.9","Brain RNA - thalamus [nTPM]":"13.7","Brain RNA - white matter [nTPM]":"18.6","Single Cell Type RNA - Adipocytes [nTPM]":"33.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"40.4","Single Cell Type RNA - Astrocytes [nTPM]":"155.7","Single Cell Type RNA - B-cells [nTPM]":"25.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"38.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"31.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"19.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"18.4","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"34.0","Single Cell Type RNA - dendritic cells [nTPM]":"24.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"14.6","Single Cell Type RNA - Early spermatids [nTPM]":"66.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.6","Single Cell Type RNA - Endothelial cells [nTPM]":"28.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"30.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"201.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.6","Single Cell Type RNA - Fibroblasts [nTPM]":"26.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.3","Single Cell Type RNA - granulocytes [nTPM]":"25.2","Single Cell Type RNA - Granulosa cells [nTPM]":"28.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"22.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.9","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"169.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.3","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"36.1","Single Cell Type RNA - Langerhans cells [nTPM]":"23.0","Single Cell Type RNA - Late spermatids [nTPM]":"109.0","Single Cell Type RNA - Leydig cells [nTPM]":"39.4","Single Cell Type RNA - Macrophages [nTPM]":"28.6","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"107.7","Single Cell Type RNA - monocytes [nTPM]":"29.7","Single Cell Type RNA - Muller glia cells [nTPM]":"17.8","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"148.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"160.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.2","Single Cell Type RNA - Paneth cells [nTPM]":"14.6","Single Cell Type RNA - Peritubular cells [nTPM]":"48.2","Single Cell Type RNA - Plasma cells [nTPM]":"23.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"22.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"18.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.7","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"31.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"35.7","Single Cell Type RNA - Spermatocytes [nTPM]":"233.8","Single Cell Type RNA - Spermatogonia [nTPM]":"57.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"43.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"50.2","Single Cell Type RNA - T-cells [nTPM]":"29.5","Single Cell Type RNA - Theca cells [nTPM]":"24.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.0","Single Cell Type RNA - Urothelial cells [nTPM]":"13.5"},{"Gene":"MMP1","Gene synonym":["CLG"],"Ensembl":"ENSG00000196611","Gene description":"Matrix metallopeptidase 1","Uniprot":["P03956"],"Chromosome":"11","Position":"102789401-102798160","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Enzymes","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Collagen degradation","Host-virus interaction"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"75.7","stomach 1":"47.6","urinary bladder":"52.2"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Pancreatic endocrine cells":"2239.5"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"head and neck cancer":"344.2"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"7","RNA brain regional specific nTPM":{"cerebral cortex":"1.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BJ hTERT+":"1139.1","HBF TERT88":"1094.4","HUVEC TERT2":"2954.4","WM-115":"1454.1"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004920"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":7730000,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - Mixed function","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA004920":"AB_2667293"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.66e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.20e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.22e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.83e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.44e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.86e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.11e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"26.7","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.3","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.1","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.1","Tissue RNA - duodenum [nTPM]":"7.9","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"4.2","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"75.7","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.1","Tissue RNA - kidney [nTPM]":"1.0","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.4","Tissue RNA - rectum [nTPM]":"6.8","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"6.9","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.6","Tissue RNA - small intestine [nTPM]":"13.0","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.1","Tissue RNA - stomach 1 [nTPM]":"47.6","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"0.1","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"1.7","Tissue RNA - urinary bladder [nTPM]":"52.2","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"1.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"1.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"517.1","Cell RNA - BJ hTERT+ [nTPM]":"1139.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"456.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"118.2","Cell RNA - CACO-2 [nTPM]":"9.1","Cell RNA - CAPAN-2 [nTPM]":"1.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.2","Cell RNA - fHDF\/TERT166 [nTPM]":"275.5","Cell RNA - GAMG [nTPM]":"175.2","Cell RNA - HaCaT [nTPM]":"4.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"160.0","Cell RNA - HBF TERT88 [nTPM]":"1094.4","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"2.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.5","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"470.1","Cell RNA - hTERT-HME1 [nTPM]":"39.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"2954.4","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.3","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.4","Cell RNA - OE19 [nTPM]":"189.3","Cell RNA - PC-3 [nTPM]":"20.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"2.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"4.8","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"1.6","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.5","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"155.0","Cell RNA - U-138 MG [nTPM]":"374.1","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"16.8","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"8.8","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"1454.1","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.1","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.1","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.6","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"90.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"30.0","Single Cell Type RNA - Club cells [nTPM]":"15.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"143.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"113.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"204.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"25.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"15.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"4.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2239.5","Single Cell Type RNA - Paneth cells [nTPM]":"1.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"10.5","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"44.3"},{"Gene":"MMP2","Gene synonym":["CLG4","CLG4A","TBE-1"],"Ensembl":"ENSG00000087245","Gene description":"Matrix metallopeptidase 2","Uniprot":["P08253"],"Chromosome":"16","Position":"55389700-55506691","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Angiogenesis","Collagen degradation"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"gallbladder":"1062.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Endometrial stromal cells":"222.4","Extravillous trophoblasts":"467.9","Fibroblasts":"815.9","Leydig cells":"340.2","Peritubular cells":"419.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"5619.3","ASC TERT1":"1623.2","hTERT-RPE1":"6400.4","U-87 MG":"1812.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001939","CAB002788"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to extracellular matrix","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":1600000000,"Blood concentration - Conc. blood MS [pg\/L]":"220000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB002788":null,"HPA001939":"AB_1079395"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.03e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.36e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.00e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.63e-2"},"Tissue RNA - adipose tissue [nTPM]":"518.9","Tissue RNA - adrenal gland [nTPM]":"68.3","Tissue RNA - amygdala [nTPM]":"3.9","Tissue RNA - appendix [nTPM]":"135.1","Tissue RNA - basal ganglia [nTPM]":"4.0","Tissue RNA - bone marrow [nTPM]":"1.2","Tissue RNA - breast [nTPM]":"328.9","Tissue RNA - cerebellum [nTPM]":"4.9","Tissue RNA - cerebral cortex [nTPM]":"7.8","Tissue RNA - cervix [nTPM]":"514.1","Tissue RNA - choroid plexus [nTPM]":"9.4","Tissue RNA - colon [nTPM]":"173.8","Tissue RNA - duodenum [nTPM]":"57.4","Tissue RNA - endometrium 1 [nTPM]":"453.6","Tissue RNA - epididymis [nTPM]":"192.6","Tissue RNA - esophagus [nTPM]":"121.5","Tissue RNA - fallopian tube [nTPM]":"190.6","Tissue RNA - gallbladder [nTPM]":"1062.9","Tissue RNA - heart muscle [nTPM]":"212.8","Tissue RNA - hippocampal formation [nTPM]":"3.6","Tissue RNA - hypothalamus [nTPM]":"5.3","Tissue RNA - kidney [nTPM]":"43.7","Tissue RNA - liver [nTPM]":"15.6","Tissue RNA - lung [nTPM]":"279.7","Tissue RNA - lymph node [nTPM]":"28.1","Tissue RNA - medulla oblongata [nTPM]":"7.6","Tissue RNA - midbrain [nTPM]":"4.9","Tissue RNA - ovary [nTPM]":"271.1","Tissue RNA - pancreas [nTPM]":"42.8","Tissue RNA - parathyroid gland [nTPM]":"13.8","Tissue RNA - pituitary gland [nTPM]":"14.7","Tissue RNA - placenta [nTPM]":"225.0","Tissue RNA - pons [nTPM]":"5.4","Tissue RNA - prostate [nTPM]":"116.8","Tissue RNA - rectum [nTPM]":"171.3","Tissue RNA - retina [nTPM]":"11.4","Tissue RNA - salivary gland [nTPM]":"124.1","Tissue RNA - seminal vesicle [nTPM]":"137.5","Tissue RNA - skeletal muscle [nTPM]":"60.8","Tissue RNA - skin 1 [nTPM]":"455.6","Tissue RNA - small intestine [nTPM]":"177.3","Tissue RNA - smooth muscle [nTPM]":"468.5","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"58.3","Tissue RNA - stomach 1 [nTPM]":"134.0","Tissue RNA - testis [nTPM]":"49.6","Tissue RNA - thalamus [nTPM]":"8.6","Tissue RNA - thymus [nTPM]":"19.8","Tissue RNA - thyroid gland [nTPM]":"113.5","Tissue RNA - tongue [nTPM]":"66.1","Tissue RNA - tonsil [nTPM]":"30.3","Tissue RNA - urinary bladder [nTPM]":"660.8","Tissue RNA - vagina [nTPM]":"238.1","Tissue RNA - white matter [nTPM]":"10.0","Cell RNA - A-431 [nTPM]":"6.5","Cell RNA - A549 [nTPM]":"3.9","Cell RNA - AF22 [nTPM]":"192.0","Cell RNA - AN3-CA [nTPM]":"2.4","Cell RNA - ASC diff [nTPM]":"5619.3","Cell RNA - ASC TERT1 [nTPM]":"1623.2","Cell RNA - BEWO [nTPM]":"312.7","Cell RNA - BJ [nTPM]":"501.4","Cell RNA - BJ hTERT+ [nTPM]":"1146.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"99.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"79.0","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"2.1","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"391.7","Cell RNA - fHDF\/TERT166 [nTPM]":"891.0","Cell RNA - GAMG [nTPM]":"37.0","Cell RNA - HaCaT [nTPM]":"54.2","Cell RNA - HAP1 [nTPM]":"1.2","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"57.0","Cell RNA - HDLM-2 [nTPM]":"0.7","Cell RNA - HEK 293 [nTPM]":"0.9","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"12.9","Cell RNA - Hep G2 [nTPM]":"3.0","Cell RNA - HHSteC [nTPM]":"530.6","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"14.8","Cell RNA - HSkMC [nTPM]":"1396.8","Cell RNA - hTCEpi [nTPM]":"1.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"512.4","Cell RNA - hTERT-HME1 [nTPM]":"4.4","Cell RNA - hTERT-RPE1 [nTPM]":"6400.4","Cell RNA - HUVEC TERT2 [nTPM]":"651.1","Cell RNA - JURKAT [nTPM]":"0.5","Cell RNA - K-562 [nTPM]":"0.7","Cell RNA - Karpas-707 [nTPM]":"2.4","Cell RNA - LHCN-M2 [nTPM]":"334.7","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"8.2","Cell RNA - NTERA-2 [nTPM]":"152.4","Cell RNA - OE19 [nTPM]":"0.5","Cell RNA - PC-3 [nTPM]":"1.6","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"46.1","Cell RNA - RPMI-8226 [nTPM]":"0.9","Cell RNA - RPTEC TERT1 [nTPM]":"16.1","Cell RNA - RT4 [nTPM]":"7.6","Cell RNA - SCLC-21H [nTPM]":"3.2","Cell RNA - SH-SY5Y [nTPM]":"345.0","Cell RNA - SiHa [nTPM]":"93.3","Cell RNA - SK-BR-3 [nTPM]":"0.8","Cell RNA - SK-MEL-30 [nTPM]":"2.1","Cell RNA - SuSa [nTPM]":"849.0","Cell RNA - T-47d [nTPM]":"1.6","Cell RNA - THP-1 [nTPM]":"36.0","Cell RNA - TIME [nTPM]":"924.6","Cell RNA - U-138 MG [nTPM]":"1546.0","Cell RNA - U-2 OS [nTPM]":"144.9","Cell RNA - U-2197 [nTPM]":"300.5","Cell RNA - U-251 MG [nTPM]":"66.9","Cell RNA - U-266\/70 [nTPM]":"1.0","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"2.2","Cell RNA - U-87 MG [nTPM]":"1812.3","Cell RNA - U-937 [nTPM]":"28.3","Cell RNA - WM-115 [nTPM]":"289.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.9","Brain RNA - basal ganglia [nTPM]":"4.0","Brain RNA - cerebellum [nTPM]":"4.9","Brain RNA - cerebral cortex [nTPM]":"7.8","Brain RNA - hippocampal formation [nTPM]":"3.6","Brain RNA - hypothalamus [nTPM]":"5.3","Brain RNA - medulla oblongata [nTPM]":"7.6","Brain RNA - midbrain [nTPM]":"4.9","Brain RNA - pons [nTPM]":"5.4","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"8.6","Brain RNA - white matter [nTPM]":"10.0","Single Cell Type RNA - Adipocytes [nTPM]":"38.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"122.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"48.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.1","Single Cell Type RNA - Bipolar cells [nTPM]":"30.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.5","Single Cell Type RNA - Early spermatids [nTPM]":"12.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"222.4","Single Cell Type RNA - Endothelial cells [nTPM]":"46.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"28.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"467.9","Single Cell Type RNA - Fibroblasts [nTPM]":"815.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"12.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"28.2","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"180.7","Single Cell Type RNA - Late spermatids [nTPM]":"40.2","Single Cell Type RNA - Leydig cells [nTPM]":"340.2","Single Cell Type RNA - Macrophages [nTPM]":"11.8","Single Cell Type RNA - Melanocytes [nTPM]":"128.1","Single Cell Type RNA - Microglial cells [nTPM]":"27.2","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"7.7","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"419.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"5.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.5","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"80.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"65.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"102.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.2","Single Cell Type RNA - T-cells [nTPM]":"10.3","Single Cell Type RNA - Theca cells [nTPM]":"35.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"4.4"},{"Gene":"MMP9","Gene synonym":["CLG4B"],"Ensembl":"ENSG00000100985","Gene description":"Matrix metallopeptidase 9","Uniprot":["P14780"],"Chromosome":"20","Position":"46008908-46016561","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Plasma proteins","Predicted secreted proteins"],"Biological process":["Collagen degradation"],"Molecular function":["Hydrolase","Metalloprotease","Protease"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"bone marrow":"376.0","lymphoid tissue":"105.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Hofbauer cells":"260.1","Langerhans cells":"606.0","Macrophages":"230.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"3.1","thalamus":"4.8"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"127","RNA blood cell specific nTPM":{"neutrophil":"272.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"341","RNA blood lineage specific nTPM":{"granulocytes":"272.2"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"13","RNA cell line specific nTPM":{"NB-4":"360.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000348","HPA001238","HPA063909","CAB068199","CAB068200","CAB068201"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":43300000,"Blood concentration - Conc. blood MS [pg\/L]":"61000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB000348":null,"CAB068199":"AB_2665675","CAB068200":"AB_2665676","CAB068201":"AB_2665677","HPA001238":"AB_1079398","HPA063909":"AB_2685150"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.62e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.55e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.65e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.19e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.05e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.65e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.85e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-3"},"Tissue RNA - adipose tissue [nTPM]":"19.5","Tissue RNA - adrenal gland [nTPM]":"0.6","Tissue RNA - amygdala [nTPM]":"0.5","Tissue RNA - appendix [nTPM]":"61.9","Tissue RNA - basal ganglia [nTPM]":"0.8","Tissue RNA - bone marrow [nTPM]":"376.0","Tissue RNA - breast [nTPM]":"8.2","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"3.1","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"5.7","Tissue RNA - duodenum [nTPM]":"11.6","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"3.0","Tissue RNA - heart muscle [nTPM]":"3.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.9","Tissue RNA - kidney [nTPM]":"2.6","Tissue RNA - liver [nTPM]":"3.8","Tissue RNA - lung [nTPM]":"21.1","Tissue RNA - lymph node [nTPM]":"103.2","Tissue RNA - medulla oblongata [nTPM]":"0.8","Tissue RNA - midbrain [nTPM]":"0.5","Tissue RNA - ovary [nTPM]":"0.8","Tissue RNA - pancreas [nTPM]":"1.6","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.1","Tissue RNA - placenta [nTPM]":"2.0","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"1.9","Tissue RNA - rectum [nTPM]":"3.4","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"3.6","Tissue RNA - seminal vesicle [nTPM]":"0.4","Tissue RNA - skeletal muscle [nTPM]":"0.7","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"12.4","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"0.4","Tissue RNA - spleen [nTPM]":"105.3","Tissue RNA - stomach 1 [nTPM]":"11.3","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"4.8","Tissue RNA - thymus [nTPM]":"17.0","Tissue RNA - thyroid gland [nTPM]":"2.1","Tissue RNA - tongue [nTPM]":"0.9","Tissue RNA - tonsil [nTPM]":"36.5","Tissue RNA - urinary bladder [nTPM]":"12.0","Tissue RNA - vagina [nTPM]":"1.1","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.2","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"3.3","Cell RNA - Daudi [nTPM]":"0.3","Cell RNA - EFO-21 [nTPM]":"28.8","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"1.4","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.3","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.6","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.4","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"360.6","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.4","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"3.7","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"1.2","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"10.3","Cell RNA - U-2 OS [nTPM]":"10.9","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.2","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.8","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"2.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"272.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"0.5","Brain RNA - basal ganglia [nTPM]":"0.8","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"3.1","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.9","Brain RNA - medulla oblongata [nTPM]":"0.8","Brain RNA - midbrain [nTPM]":"0.5","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.4","Brain RNA - thalamus [nTPM]":"4.8","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"3.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"34.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"3.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"2.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"7.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"2.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"260.1","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.5","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"606.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"230.6","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.3","Single Cell Type RNA - Muller glia cells [nTPM]":"1.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.8","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"45.5","Single Cell Type RNA - Spermatocytes [nTPM]":"6.7","Single Cell Type RNA - Spermatogonia [nTPM]":"11.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.9","Single Cell Type RNA - T-cells [nTPM]":"3.4","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"MPL","Gene synonym":["CD110","THPOR","TPOR"],"Ensembl":"ENSG00000117400","Gene description":"MPL proto-oncogene, thrombopoietin receptor","Uniprot":["P40238"],"Chromosome":"1","Position":"43337818-43354466","Protein class":["Cancer-related genes","CD markers","Disease related genes","FDA approved drug targets","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nTPM":{"Erythroid cells":"3.0","Excitatory neurons":"2.0","Oligodendrocytes":"1.0"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.4"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.4"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"57","RNA cell line specific nTPM":{"HEL":"77.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebral cortex":"1.5"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007619"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"HPA007619":"AB_1854080"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.71e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.22e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.83e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.94e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.6","Tissue RNA - adrenal gland [nTPM]":"0.4","Tissue RNA - amygdala [nTPM]":"0.8","Tissue RNA - appendix [nTPM]":"0.2","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"0.8","Tissue RNA - cerebral cortex [nTPM]":"1.3","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.1","Tissue RNA - colon [nTPM]":"0.3","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"0.7","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"0.5","Tissue RNA - fallopian tube [nTPM]":"0.8","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"1.2","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"0.6","Tissue RNA - lymph node [nTPM]":"0.2","Tissue RNA - medulla oblongata [nTPM]":"1.2","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"2.9","Tissue RNA - pancreas [nTPM]":"0.8","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.3","Tissue RNA - pons [nTPM]":"1.1","Tissue RNA - prostate [nTPM]":"0.9","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"0.4","Tissue RNA - seminal vesicle [nTPM]":"0.7","Tissue RNA - skeletal muscle [nTPM]":"0.6","Tissue RNA - skin 1 [nTPM]":"0.5","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.7","Tissue RNA - spinal cord [nTPM]":"0.7","Tissue RNA - spleen [nTPM]":"0.4","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"1.1","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.9","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"2.8","Cell RNA - A-431 [nTPM]":"0.4","Cell RNA - A549 [nTPM]":"0.7","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"1.3","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.4","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"77.4","Cell RNA - HeLa [nTPM]":"1.2","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.2","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.3","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.1","Cell RNA - REH [nTPM]":"0.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.7","Cell RNA - RT4 [nTPM]":"0.6","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.2","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.9","Blood RNA - classical monocyte [nTPM]":"0.1","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"0.2","Blood RNA - naive CD8 T-cell [nTPM]":"0.2","Blood RNA - neutrophil [nTPM]":"1.4","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"1.8","Brain RNA - amygdala [nTPM]":"0.8","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"0.8","Brain RNA - cerebral cortex [nTPM]":"1.3","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"1.2","Brain RNA - medulla oblongata [nTPM]":"1.2","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"1.1","Brain RNA - spinal cord [nTPM]":"0.7","Brain RNA - thalamus [nTPM]":"1.1","Brain RNA - white matter [nTPM]":"2.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MSH2","Gene synonym":["COCA1","HNPCC","HNPCC1"],"Ensembl":"ENSG00000095002","Gene description":"MutS homolog 2","Uniprot":["P43246"],"Chromosome":"2","Position":"47403067-47663146","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"46.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009572","HPA066845","CAB070867"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"28000","Blood expression cluster":"Cluster 48: NK-cells - Unknown function","Tissue expression cluster":"Cluster 20: Retina & Lymphoid tissues - Unknown function","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 12: Non-specific - Cell cycle regulation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB009572":"AB_2144828","CAB070867":null,"HPA066845":"AB_2732752"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.44e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.31e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.72e-9"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.63e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.20e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.74e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Tissue RNA - adipose tissue [nTPM]":"8.1","Tissue RNA - adrenal gland [nTPM]":"7.5","Tissue RNA - amygdala [nTPM]":"8.3","Tissue RNA - appendix [nTPM]":"12.8","Tissue RNA - basal ganglia [nTPM]":"10.5","Tissue RNA - bone marrow [nTPM]":"15.7","Tissue RNA - breast [nTPM]":"15.7","Tissue RNA - cerebellum [nTPM]":"14.6","Tissue RNA - cerebral cortex [nTPM]":"10.6","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"12.2","Tissue RNA - colon [nTPM]":"11.9","Tissue RNA - duodenum [nTPM]":"7.8","Tissue RNA - endometrium 1 [nTPM]":"11.7","Tissue RNA - epididymis [nTPM]":"14.0","Tissue RNA - esophagus [nTPM]":"9.5","Tissue RNA - fallopian tube [nTPM]":"12.4","Tissue RNA - gallbladder [nTPM]":"5.8","Tissue RNA - heart muscle [nTPM]":"10.1","Tissue RNA - hippocampal formation [nTPM]":"9.6","Tissue RNA - hypothalamus [nTPM]":"9.0","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"6.7","Tissue RNA - lung [nTPM]":"8.1","Tissue RNA - lymph node [nTPM]":"23.7","Tissue RNA - medulla oblongata [nTPM]":"8.6","Tissue RNA - midbrain [nTPM]":"8.0","Tissue RNA - ovary [nTPM]":"8.7","Tissue RNA - pancreas [nTPM]":"6.5","Tissue RNA - parathyroid gland [nTPM]":"14.8","Tissue RNA - pituitary gland [nTPM]":"6.2","Tissue RNA - placenta [nTPM]":"11.6","Tissue RNA - pons [nTPM]":"9.5","Tissue RNA - prostate [nTPM]":"8.6","Tissue RNA - rectum [nTPM]":"15.0","Tissue RNA - retina [nTPM]":"34.9","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"7.7","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"11.1","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"8.8","Tissue RNA - spinal cord [nTPM]":"8.5","Tissue RNA - spleen [nTPM]":"10.8","Tissue RNA - stomach 1 [nTPM]":"8.1","Tissue RNA - testis [nTPM]":"16.2","Tissue RNA - thalamus [nTPM]":"7.9","Tissue RNA - thymus [nTPM]":"32.6","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.2","Tissue RNA - tonsil [nTPM]":"25.0","Tissue RNA - urinary bladder [nTPM]":"7.9","Tissue RNA - vagina [nTPM]":"6.4","Tissue RNA - white matter [nTPM]":"8.9","Cell RNA - A-431 [nTPM]":"114.3","Cell RNA - A549 [nTPM]":"35.3","Cell RNA - AF22 [nTPM]":"103.3","Cell RNA - AN3-CA [nTPM]":"57.9","Cell RNA - ASC diff [nTPM]":"7.3","Cell RNA - ASC TERT1 [nTPM]":"21.2","Cell RNA - BEWO [nTPM]":"64.3","Cell RNA - BJ [nTPM]":"62.9","Cell RNA - BJ hTERT+ [nTPM]":"33.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"80.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"76.9","Cell RNA - CACO-2 [nTPM]":"72.3","Cell RNA - CAPAN-2 [nTPM]":"50.1","Cell RNA - Daudi [nTPM]":"141.2","Cell RNA - EFO-21 [nTPM]":"84.6","Cell RNA - fHDF\/TERT166 [nTPM]":"23.8","Cell RNA - GAMG [nTPM]":"56.6","Cell RNA - HaCaT [nTPM]":"49.8","Cell RNA - HAP1 [nTPM]":"78.6","Cell RNA - HBEC3-KT [nTPM]":"37.4","Cell RNA - HBF TERT88 [nTPM]":"122.3","Cell RNA - HDLM-2 [nTPM]":"68.1","Cell RNA - HEK 293 [nTPM]":"55.8","Cell RNA - HEL [nTPM]":"99.3","Cell RNA - HeLa [nTPM]":"42.3","Cell RNA - Hep G2 [nTPM]":"65.6","Cell RNA - HHSteC [nTPM]":"7.7","Cell RNA - HL-60 [nTPM]":"97.7","Cell RNA - HMC-1 [nTPM]":"34.9","Cell RNA - HSkMC [nTPM]":"12.3","Cell RNA - hTCEpi [nTPM]":"11.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"68.1","Cell RNA - hTERT-HME1 [nTPM]":"19.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.1","Cell RNA - HUVEC TERT2 [nTPM]":"45.2","Cell RNA - JURKAT [nTPM]":"3.9","Cell RNA - K-562 [nTPM]":"165.1","Cell RNA - Karpas-707 [nTPM]":"34.0","Cell RNA - LHCN-M2 [nTPM]":"63.1","Cell RNA - MCF7 [nTPM]":"44.2","Cell RNA - MOLT-4 [nTPM]":"119.6","Cell RNA - NB-4 [nTPM]":"75.4","Cell RNA - NTERA-2 [nTPM]":"195.7","Cell RNA - OE19 [nTPM]":"69.3","Cell RNA - PC-3 [nTPM]":"45.1","Cell RNA - REH [nTPM]":"151.1","Cell RNA - RH-30 [nTPM]":"182.2","Cell RNA - RPMI-8226 [nTPM]":"84.4","Cell RNA - RPTEC TERT1 [nTPM]":"35.8","Cell RNA - RT4 [nTPM]":"57.3","Cell RNA - SCLC-21H [nTPM]":"85.9","Cell RNA - SH-SY5Y [nTPM]":"91.6","Cell RNA - SiHa [nTPM]":"58.4","Cell RNA - SK-BR-3 [nTPM]":"49.2","Cell RNA - SK-MEL-30 [nTPM]":"48.0","Cell RNA - SuSa [nTPM]":"83.6","Cell RNA - T-47d [nTPM]":"46.9","Cell RNA - THP-1 [nTPM]":"38.8","Cell RNA - TIME [nTPM]":"18.7","Cell RNA - U-138 MG [nTPM]":"55.5","Cell RNA - U-2 OS [nTPM]":"70.9","Cell RNA - U-2197 [nTPM]":"57.1","Cell RNA - U-251 MG [nTPM]":"74.6","Cell RNA - U-266\/70 [nTPM]":"20.8","Cell RNA - U-266\/84 [nTPM]":"63.4","Cell RNA - U-698 [nTPM]":"180.1","Cell RNA - U-87 MG [nTPM]":"33.1","Cell RNA - U-937 [nTPM]":"72.5","Cell RNA - WM-115 [nTPM]":"35.4","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"1.3","Blood RNA - eosinophil [nTPM]":"4.9","Blood RNA - gdT-cell [nTPM]":"8.0","Blood RNA - intermediate monocyte [nTPM]":"4.4","Blood RNA - MAIT T-cell [nTPM]":"9.3","Blood RNA - memory B-cell [nTPM]":"6.7","Blood RNA - memory CD4 T-cell [nTPM]":"7.7","Blood RNA - memory CD8 T-cell [nTPM]":"10.3","Blood RNA - myeloid DC [nTPM]":"2.5","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"12.6","Blood RNA - naive CD8 T-cell [nTPM]":"13.1","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"14.2","Blood RNA - non-classical monocyte [nTPM]":"3.9","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"11.8","Blood RNA - total PBMC [nTPM]":"6.5","Brain RNA - amygdala [nTPM]":"8.3","Brain RNA - basal ganglia [nTPM]":"10.5","Brain RNA - cerebellum [nTPM]":"14.6","Brain RNA - cerebral cortex [nTPM]":"10.6","Brain RNA - hippocampal formation [nTPM]":"9.6","Brain RNA - hypothalamus [nTPM]":"9.0","Brain RNA - medulla oblongata [nTPM]":"8.6","Brain RNA - midbrain [nTPM]":"8.0","Brain RNA - pons [nTPM]":"9.5","Brain RNA - spinal cord [nTPM]":"8.5","Brain RNA - thalamus [nTPM]":"7.9","Brain RNA - white matter [nTPM]":"8.9","Single Cell Type RNA - Adipocytes [nTPM]":"14.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.5","Single Cell Type RNA - Astrocytes [nTPM]":"18.6","Single Cell Type RNA - B-cells [nTPM]":"13.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"8.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"17.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"7.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"15.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"12.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"45.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.9","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"6.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"21.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.3","Single Cell Type RNA - Endothelial cells [nTPM]":"13.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"3.5","Single Cell Type RNA - Erythroid cells [nTPM]":"54.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"59.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"8.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.8","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.4","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"58.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.1","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"4.1","Single Cell Type RNA - Langerhans cells [nTPM]":"4.6","Single Cell Type RNA - Late spermatids [nTPM]":"22.8","Single Cell Type RNA - Leydig cells [nTPM]":"5.3","Single Cell Type RNA - Macrophages [nTPM]":"5.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"5.5","Single Cell Type RNA - Muller glia cells [nTPM]":"22.6","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"35.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"54.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.3","Single Cell Type RNA - Paneth cells [nTPM]":"5.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"12.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"41.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.0","Single Cell Type RNA - Spermatocytes [nTPM]":"56.5","Single Cell Type RNA - Spermatogonia [nTPM]":"50.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.1","Single Cell Type RNA - T-cells [nTPM]":"12.8","Single Cell Type RNA - Theca cells [nTPM]":"24.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.5","Single Cell Type RNA - Urothelial cells [nTPM]":"3.8"},{"Gene":"MSH3","Gene synonym":["DUP","MRP1"],"Ensembl":"ENSG00000113318","Gene description":"MutS homolog 3","Uniprot":["P20585"],"Chromosome":"5","Position":"80654652-80876815","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"95.1","Inhibitory neurons":"98.9","Oligodendrocytes":"92.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA036081"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear bodies"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 81: Kidney & Liver - Metabolism","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"HPA036081":"AB_10673229"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.61e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.90e-5"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.17e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.77e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Tissue RNA - adipose tissue [nTPM]":"9.4","Tissue RNA - adrenal gland [nTPM]":"4.6","Tissue RNA - amygdala [nTPM]":"1.8","Tissue RNA - appendix [nTPM]":"4.3","Tissue RNA - basal ganglia [nTPM]":"2.4","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"2.0","Tissue RNA - cervix [nTPM]":"6.6","Tissue RNA - choroid plexus [nTPM]":"1.5","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"6.0","Tissue RNA - endometrium 1 [nTPM]":"5.2","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"5.0","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"5.7","Tissue RNA - heart muscle [nTPM]":"4.9","Tissue RNA - hippocampal formation [nTPM]":"1.7","Tissue RNA - hypothalamus [nTPM]":"2.0","Tissue RNA - kidney [nTPM]":"12.5","Tissue RNA - liver [nTPM]":"11.4","Tissue RNA - lung [nTPM]":"4.2","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"1.7","Tissue RNA - midbrain [nTPM]":"2.0","Tissue RNA - ovary [nTPM]":"5.3","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"8.8","Tissue RNA - pituitary gland [nTPM]":"3.3","Tissue RNA - placenta [nTPM]":"4.3","Tissue RNA - pons [nTPM]":"1.7","Tissue RNA - prostate [nTPM]":"5.2","Tissue RNA - rectum [nTPM]":"6.2","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"5.1","Tissue RNA - skin 1 [nTPM]":"5.1","Tissue RNA - small intestine [nTPM]":"5.6","Tissue RNA - smooth muscle [nTPM]":"5.1","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"4.1","Tissue RNA - stomach 1 [nTPM]":"5.0","Tissue RNA - testis [nTPM]":"3.9","Tissue RNA - thalamus [nTPM]":"2.5","Tissue RNA - thymus [nTPM]":"7.1","Tissue RNA - thyroid gland [nTPM]":"10.8","Tissue RNA - tongue [nTPM]":"4.7","Tissue RNA - tonsil [nTPM]":"6.1","Tissue RNA - urinary bladder [nTPM]":"6.3","Tissue RNA - vagina [nTPM]":"3.9","Tissue RNA - white matter [nTPM]":"2.0","Cell RNA - A-431 [nTPM]":"12.4","Cell RNA - A549 [nTPM]":"15.0","Cell RNA - AF22 [nTPM]":"11.7","Cell RNA - AN3-CA [nTPM]":"13.1","Cell RNA - ASC diff [nTPM]":"6.6","Cell RNA - ASC TERT1 [nTPM]":"12.3","Cell RNA - BEWO [nTPM]":"16.6","Cell RNA - BJ [nTPM]":"12.2","Cell RNA - BJ hTERT+ [nTPM]":"11.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.7","Cell RNA - CACO-2 [nTPM]":"10.0","Cell RNA - CAPAN-2 [nTPM]":"15.6","Cell RNA - Daudi [nTPM]":"22.2","Cell RNA - EFO-21 [nTPM]":"14.0","Cell RNA - fHDF\/TERT166 [nTPM]":"15.3","Cell RNA - GAMG [nTPM]":"12.8","Cell RNA - HaCaT [nTPM]":"10.4","Cell RNA - HAP1 [nTPM]":"15.6","Cell RNA - HBEC3-KT [nTPM]":"20.5","Cell RNA - HBF TERT88 [nTPM]":"17.3","Cell RNA - HDLM-2 [nTPM]":"14.2","Cell RNA - HEK 293 [nTPM]":"13.9","Cell RNA - HEL [nTPM]":"8.4","Cell RNA - HeLa [nTPM]":"13.4","Cell RNA - Hep G2 [nTPM]":"9.9","Cell RNA - HHSteC [nTPM]":"6.8","Cell RNA - HL-60 [nTPM]":"9.9","Cell RNA - HMC-1 [nTPM]":"8.5","Cell RNA - HSkMC [nTPM]":"10.9","Cell RNA - hTCEpi [nTPM]":"9.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"15.8","Cell RNA - hTERT-HME1 [nTPM]":"16.6","Cell RNA - hTERT-RPE1 [nTPM]":"13.8","Cell RNA - HUVEC TERT2 [nTPM]":"12.9","Cell RNA - JURKAT [nTPM]":"7.9","Cell RNA - K-562 [nTPM]":"12.1","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"16.1","Cell RNA - MCF7 [nTPM]":"11.9","Cell RNA - MOLT-4 [nTPM]":"19.0","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"9.0","Cell RNA - OE19 [nTPM]":"4.8","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"13.2","Cell RNA - RH-30 [nTPM]":"24.2","Cell RNA - RPMI-8226 [nTPM]":"16.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.2","Cell RNA - RT4 [nTPM]":"13.0","Cell RNA - SCLC-21H [nTPM]":"11.6","Cell RNA - SH-SY5Y [nTPM]":"13.9","Cell RNA - SiHa [nTPM]":"10.4","Cell RNA - SK-BR-3 [nTPM]":"11.5","Cell RNA - SK-MEL-30 [nTPM]":"13.0","Cell RNA - SuSa [nTPM]":"14.4","Cell RNA - T-47d [nTPM]":"15.2","Cell RNA - THP-1 [nTPM]":"9.4","Cell RNA - TIME [nTPM]":"12.4","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"9.5","Cell RNA - U-2197 [nTPM]":"6.2","Cell RNA - U-251 MG [nTPM]":"23.0","Cell RNA - U-266\/70 [nTPM]":"8.7","Cell RNA - U-266\/84 [nTPM]":"15.6","Cell RNA - U-698 [nTPM]":"21.6","Cell RNA - U-87 MG [nTPM]":"12.2","Cell RNA - U-937 [nTPM]":"16.8","Cell RNA - WM-115 [nTPM]":"10.2","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"2.9","Blood RNA - eosinophil [nTPM]":"1.9","Blood RNA - gdT-cell [nTPM]":"3.3","Blood RNA - intermediate monocyte [nTPM]":"3.4","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"3.4","Blood RNA - memory CD4 T-cell [nTPM]":"3.5","Blood RNA - memory CD8 T-cell [nTPM]":"3.6","Blood RNA - myeloid DC [nTPM]":"3.3","Blood RNA - naive B-cell [nTPM]":"2.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.6","Blood RNA - neutrophil [nTPM]":"1.7","Blood RNA - NK-cell [nTPM]":"3.1","Blood RNA - non-classical monocyte [nTPM]":"4.6","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"4.8","Blood RNA - total PBMC [nTPM]":"2.4","Brain RNA - amygdala [nTPM]":"1.8","Brain RNA - basal ganglia [nTPM]":"2.4","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"2.0","Brain RNA - hippocampal formation [nTPM]":"1.7","Brain RNA - hypothalamus [nTPM]":"2.0","Brain RNA - medulla oblongata [nTPM]":"1.7","Brain RNA - midbrain [nTPM]":"2.0","Brain RNA - pons [nTPM]":"1.7","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.5","Brain RNA - white matter [nTPM]":"2.0","Single Cell Type RNA - Adipocytes [nTPM]":"16.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.3","Single Cell Type RNA - Astrocytes [nTPM]":"66.9","Single Cell Type RNA - B-cells [nTPM]":"18.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"25.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"8.6","Single Cell Type RNA - Club cells [nTPM]":"14.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"18.9","Single Cell Type RNA - dendritic cells [nTPM]":"18.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"12.4","Single Cell Type RNA - Early spermatids [nTPM]":"14.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.2","Single Cell Type RNA - Endothelial cells [nTPM]":"12.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.5","Single Cell Type RNA - Erythroid cells [nTPM]":"17.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"95.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"12.9","Single Cell Type RNA - Fibroblasts [nTPM]":"15.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"31.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.9","Single Cell Type RNA - granulocytes [nTPM]":"8.2","Single Cell Type RNA - Granulosa cells [nTPM]":"19.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.5","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"98.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"13.2","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"13.0","Single Cell Type RNA - Langerhans cells [nTPM]":"7.0","Single Cell Type RNA - Late spermatids [nTPM]":"17.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"16.3","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"72.1","Single Cell Type RNA - monocytes [nTPM]":"19.9","Single Cell Type RNA - Muller glia cells [nTPM]":"22.5","Single Cell Type RNA - NK-cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"71.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"92.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.6","Single Cell Type RNA - Paneth cells [nTPM]":"9.6","Single Cell Type RNA - Peritubular cells [nTPM]":"25.9","Single Cell Type RNA - Plasma cells [nTPM]":"22.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"6.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"43.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"65.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"28.3","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.7","Single Cell Type RNA - Spermatogonia [nTPM]":"25.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"13.1","Single Cell Type RNA - T-cells [nTPM]":"25.4","Single Cell Type RNA - Theca cells [nTPM]":"14.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.4","Single Cell Type RNA - Urothelial cells [nTPM]":"10.7"},{"Gene":"MSH6","Gene synonym":["GTBP"],"Ensembl":"ENSG00000116062","Gene description":"MutS homolog 6","Uniprot":["P52701"],"Chromosome":"2","Position":"47695530-47810063","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Host-virus interaction"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"119.6","Theca cells":"114.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"testis cancer":"31.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009091","HPA028376","HPA028446","CAB070870"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Golgi apparatus","Vesicles"],"Antibody RRID":{"CAB009091":"AB_670083","CAB070870":"AB_2144959","HPA028376":"AB_10598909","HPA028446":"AB_10602182"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.34e-4"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.86e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.74e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.99e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.68e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"11.7","Tissue RNA - adrenal gland [nTPM]":"22.7","Tissue RNA - amygdala [nTPM]":"9.3","Tissue RNA - appendix [nTPM]":"17.7","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"24.0","Tissue RNA - breast [nTPM]":"16.2","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"12.7","Tissue RNA - cervix [nTPM]":"15.5","Tissue RNA - choroid plexus [nTPM]":"12.7","Tissue RNA - colon [nTPM]":"13.0","Tissue RNA - duodenum [nTPM]":"9.0","Tissue RNA - endometrium 1 [nTPM]":"27.7","Tissue RNA - epididymis [nTPM]":"10.2","Tissue RNA - esophagus [nTPM]":"11.7","Tissue RNA - fallopian tube [nTPM]":"17.8","Tissue RNA - gallbladder [nTPM]":"10.9","Tissue RNA - heart muscle [nTPM]":"9.3","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"12.1","Tissue RNA - liver [nTPM]":"19.8","Tissue RNA - lung [nTPM]":"11.6","Tissue RNA - lymph node [nTPM]":"28.4","Tissue RNA - medulla oblongata [nTPM]":"12.7","Tissue RNA - midbrain [nTPM]":"11.7","Tissue RNA - ovary [nTPM]":"53.0","Tissue RNA - pancreas [nTPM]":"31.3","Tissue RNA - parathyroid gland [nTPM]":"17.0","Tissue RNA - pituitary gland [nTPM]":"9.8","Tissue RNA - placenta [nTPM]":"20.3","Tissue RNA - pons [nTPM]":"13.0","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"12.4","Tissue RNA - retina [nTPM]":"21.6","Tissue RNA - salivary gland [nTPM]":"10.8","Tissue RNA - seminal vesicle [nTPM]":"15.6","Tissue RNA - skeletal muscle [nTPM]":"10.5","Tissue RNA - skin 1 [nTPM]":"13.1","Tissue RNA - small intestine [nTPM]":"9.8","Tissue RNA - smooth muscle [nTPM]":"27.2","Tissue RNA - spinal cord [nTPM]":"10.7","Tissue RNA - spleen [nTPM]":"12.7","Tissue RNA - stomach 1 [nTPM]":"10.9","Tissue RNA - testis [nTPM]":"35.3","Tissue RNA - thalamus [nTPM]":"11.3","Tissue RNA - thymus [nTPM]":"36.3","Tissue RNA - thyroid gland [nTPM]":"17.2","Tissue RNA - tongue [nTPM]":"11.2","Tissue RNA - tonsil [nTPM]":"31.0","Tissue RNA - urinary bladder [nTPM]":"12.8","Tissue RNA - vagina [nTPM]":"12.2","Tissue RNA - white matter [nTPM]":"19.9","Cell RNA - A-431 [nTPM]":"116.5","Cell RNA - A549 [nTPM]":"77.6","Cell RNA - AF22 [nTPM]":"128.4","Cell RNA - AN3-CA [nTPM]":"37.5","Cell RNA - ASC diff [nTPM]":"42.3","Cell RNA - ASC TERT1 [nTPM]":"46.3","Cell RNA - BEWO [nTPM]":"67.9","Cell RNA - BJ [nTPM]":"63.6","Cell RNA - BJ hTERT+ [nTPM]":"51.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"60.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.8","Cell RNA - CACO-2 [nTPM]":"67.2","Cell RNA - CAPAN-2 [nTPM]":"41.4","Cell RNA - Daudi [nTPM]":"158.1","Cell RNA - EFO-21 [nTPM]":"84.5","Cell RNA - fHDF\/TERT166 [nTPM]":"59.5","Cell RNA - GAMG [nTPM]":"82.0","Cell RNA - HaCaT [nTPM]":"46.0","Cell RNA - HAP1 [nTPM]":"130.3","Cell RNA - HBEC3-KT [nTPM]":"74.3","Cell RNA - HBF TERT88 [nTPM]":"82.1","Cell RNA - HDLM-2 [nTPM]":"80.7","Cell RNA - HEK 293 [nTPM]":"69.0","Cell RNA - HEL [nTPM]":"117.0","Cell RNA - HeLa [nTPM]":"60.8","Cell RNA - Hep G2 [nTPM]":"71.1","Cell RNA - HHSteC [nTPM]":"28.8","Cell RNA - HL-60 [nTPM]":"131.5","Cell RNA - HMC-1 [nTPM]":"37.8","Cell RNA - HSkMC [nTPM]":"38.6","Cell RNA - hTCEpi [nTPM]":"28.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"60.7","Cell RNA - hTERT-HME1 [nTPM]":"41.6","Cell RNA - hTERT-RPE1 [nTPM]":"53.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.8","Cell RNA - JURKAT [nTPM]":"5.3","Cell RNA - K-562 [nTPM]":"115.9","Cell RNA - Karpas-707 [nTPM]":"69.8","Cell RNA - LHCN-M2 [nTPM]":"61.8","Cell RNA - MCF7 [nTPM]":"85.5","Cell RNA - MOLT-4 [nTPM]":"144.2","Cell RNA - NB-4 [nTPM]":"80.1","Cell RNA - NTERA-2 [nTPM]":"130.7","Cell RNA - OE19 [nTPM]":"81.3","Cell RNA - PC-3 [nTPM]":"37.7","Cell RNA - REH [nTPM]":"219.6","Cell RNA - RH-30 [nTPM]":"204.3","Cell RNA - RPMI-8226 [nTPM]":"84.7","Cell RNA - RPTEC TERT1 [nTPM]":"44.5","Cell RNA - RT4 [nTPM]":"76.2","Cell RNA - SCLC-21H [nTPM]":"92.8","Cell RNA - SH-SY5Y [nTPM]":"100.3","Cell RNA - SiHa [nTPM]":"79.1","Cell RNA - SK-BR-3 [nTPM]":"40.4","Cell RNA - SK-MEL-30 [nTPM]":"42.7","Cell RNA - SuSa [nTPM]":"124.3","Cell RNA - T-47d [nTPM]":"54.6","Cell RNA - THP-1 [nTPM]":"42.6","Cell RNA - TIME [nTPM]":"33.4","Cell RNA - U-138 MG [nTPM]":"72.2","Cell RNA - U-2 OS [nTPM]":"92.3","Cell RNA - U-2197 [nTPM]":"54.6","Cell RNA - U-251 MG [nTPM]":"80.6","Cell RNA - U-266\/70 [nTPM]":"63.8","Cell RNA - U-266\/84 [nTPM]":"79.3","Cell RNA - U-698 [nTPM]":"276.2","Cell RNA - U-87 MG [nTPM]":"61.9","Cell RNA - U-937 [nTPM]":"77.9","Cell RNA - WM-115 [nTPM]":"42.4","Blood RNA - basophil [nTPM]":"7.7","Blood RNA - classical monocyte [nTPM]":"3.7","Blood RNA - eosinophil [nTPM]":"3.8","Blood RNA - gdT-cell [nTPM]":"4.8","Blood RNA - intermediate monocyte [nTPM]":"6.2","Blood RNA - MAIT T-cell [nTPM]":"5.5","Blood RNA - memory B-cell [nTPM]":"4.3","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.0","Blood RNA - myeloid DC [nTPM]":"5.5","Blood RNA - naive B-cell [nTPM]":"4.2","Blood RNA - naive CD4 T-cell [nTPM]":"8.4","Blood RNA - naive CD8 T-cell [nTPM]":"4.5","Blood RNA - neutrophil [nTPM]":"2.5","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"6.4","Blood RNA - plasmacytoid DC [nTPM]":"2.7","Blood RNA - T-reg [nTPM]":"5.3","Blood RNA - total PBMC [nTPM]":"3.6","Brain RNA - amygdala [nTPM]":"9.3","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"12.7","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"12.7","Brain RNA - midbrain [nTPM]":"11.7","Brain RNA - pons [nTPM]":"13.0","Brain RNA - spinal cord [nTPM]":"10.7","Brain RNA - thalamus [nTPM]":"11.3","Brain RNA - white matter [nTPM]":"19.9","Single Cell Type RNA - Adipocytes [nTPM]":"19.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"28.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.4","Single Cell Type RNA - Astrocytes [nTPM]":"5.9","Single Cell Type RNA - B-cells [nTPM]":"19.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"22.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"25.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"21.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"35.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"35.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"7.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.7","Single Cell Type RNA - Early spermatids [nTPM]":"46.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"31.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"47.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"9.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.8","Single Cell Type RNA - Fibroblasts [nTPM]":"24.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"31.7","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"119.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"10.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.0","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"12.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"9.7","Single Cell Type RNA - Ionocytes [nTPM]":"20.3","Single Cell Type RNA - Kupffer cells [nTPM]":"5.6","Single Cell Type RNA - Langerhans cells [nTPM]":"13.2","Single Cell Type RNA - Late spermatids [nTPM]":"17.5","Single Cell Type RNA - Leydig cells [nTPM]":"25.4","Single Cell Type RNA - Macrophages [nTPM]":"16.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"10.0","Single Cell Type RNA - Muller glia cells [nTPM]":"22.7","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"9.1","Single Cell Type RNA - Paneth cells [nTPM]":"3.7","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"31.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"31.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"27.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"33.0","Single Cell Type RNA - Spermatocytes [nTPM]":"54.3","Single Cell Type RNA - Spermatogonia [nTPM]":"48.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"22.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"9.6","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"114.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.7"},{"Gene":"MYB","Gene synonym":["c-myb"],"Ensembl":"ENSG00000118513","Gene description":"MYB proto-oncogene, transcription factor","Uniprot":["P10242"],"Chromosome":"6","Position":"135181308-135219173","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"bone marrow":"35.2","breast":"20.1","intestine":"26.5","lymphoid tissue":"66.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"47.8","Erythroid cells":"83.2","granulocytes":"26.0","Intestinal goblet cells":"32.7","Ionocytes":"26.4","Respiratory ciliated cells":"37.2","Undifferentiated cells":"52.0"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"breast cancer":"17.7","colorectal cancer":"16.4","stomach cancer":"5.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"4.6","eosinophil":"5.4","plasmacytoid DC":"1.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"dendritic cells":"1.5","granulocytes":"5.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HL-60":"219.8","MOLT-4":"403.1","NB-4":"208.5","REH":"244.9","THP-1":"343.8","U-937":"186.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017704","HPA071605"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB017704":null,"HPA071605":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.44e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.65e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.87e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.04e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"5.3","Tissue RNA - basal ganglia [nTPM]":"1.7","Tissue RNA - bone marrow [nTPM]":"35.2","Tissue RNA - breast [nTPM]":"20.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.7","Tissue RNA - cervix [nTPM]":"1.6","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"25.3","Tissue RNA - duodenum [nTPM]":"10.9","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"3.0","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"0.1","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.4","Tissue RNA - lung [nTPM]":"2.0","Tissue RNA - lymph node [nTPM]":"6.3","Tissue RNA - medulla oblongata [nTPM]":"0.9","Tissue RNA - midbrain [nTPM]":"1.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"3.6","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.6","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"26.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.6","Tissue RNA - seminal vesicle [nTPM]":"0.9","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"3.0","Tissue RNA - small intestine [nTPM]":"9.4","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"1.2","Tissue RNA - stomach 1 [nTPM]":"2.0","Tissue RNA - testis [nTPM]":"0.7","Tissue RNA - thalamus [nTPM]":"0.3","Tissue RNA - thymus [nTPM]":"66.1","Tissue RNA - thyroid gland [nTPM]":"0.1","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"1.3","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"1.8","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"1.9","Cell RNA - AN3-CA [nTPM]":"3.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"1.0","Cell RNA - BJ hTERT+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.1","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"10.9","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.4","Cell RNA - HaCaT [nTPM]":"0.9","Cell RNA - HAP1 [nTPM]":"5.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"18.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"138.8","Cell RNA - HeLa [nTPM]":"1.0","Cell RNA - Hep G2 [nTPM]":"0.5","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"219.8","Cell RNA - HMC-1 [nTPM]":"105.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"133.4","Cell RNA - K-562 [nTPM]":"114.6","Cell RNA - Karpas-707 [nTPM]":"20.1","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"11.6","Cell RNA - MOLT-4 [nTPM]":"403.1","Cell RNA - NB-4 [nTPM]":"208.5","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"19.2","Cell RNA - PC-3 [nTPM]":"1.7","Cell RNA - REH [nTPM]":"244.9","Cell RNA - RH-30 [nTPM]":"5.9","Cell RNA - RPMI-8226 [nTPM]":"33.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.3","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"10.5","Cell RNA - SH-SY5Y [nTPM]":"6.9","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"10.4","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"7.9","Cell RNA - THP-1 [nTPM]":"343.8","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"1.6","Cell RNA - U-2197 [nTPM]":"7.9","Cell RNA - U-251 MG [nTPM]":"2.4","Cell RNA - U-266\/70 [nTPM]":"27.7","Cell RNA - U-266\/84 [nTPM]":"7.7","Cell RNA - U-698 [nTPM]":"66.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"186.1","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"0.7","Blood RNA - eosinophil [nTPM]":"5.4","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"1.5","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.7","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.7","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.9","Brain RNA - midbrain [nTPM]":"1.0","Brain RNA - pons [nTPM]":"0.6","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.3","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"2.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"47.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"9.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"24.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.6","Single Cell Type RNA - Erythroid cells [nTPM]":"83.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.4","Single Cell Type RNA - Fibroblasts [nTPM]":"0.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"26.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.7","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"1.2","Single Cell Type RNA - Langerhans cells [nTPM]":"1.7","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"2.1","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"10.2","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"10.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"7.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"52.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"MYC","Gene synonym":["bHLHe39","c-Myc","MYCC"],"Ensembl":"ENSG00000136997","Gene description":"MYC proto-oncogene, bHLH transcription factor","Uniprot":["P01106"],"Chromosome":"8","Position":"127735434-127742951","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"254.6","skin 1":"289.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"1013.3","Basal prostatic cells":"1080.5","Basal squamous epithelial cells":"1270.8","Squamous epithelial cells":"768.8","Suprabasal keratinocytes":"1070.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RPMI-8226":"1069.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000084","CAB010307","HPA055893","HPA066556"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 32: T-cells - Unknown function","Tissue expression cluster":"Cluster 31: Skin - Epidermis development","Cell line expression cluster":"Cluster 25: RPMI-8226 - Immune response","Single cell expression cluster":"Cluster 61: Squamous epithelial cells - Keratinization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000084":null,"CAB010307":"AB_631274","HPA055893":"AB_2682960","HPA066556":"AB_2685691"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.94e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.80e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.94e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.52e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.19e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.86e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.49e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.96e-5"},"Tissue RNA - adipose tissue [nTPM]":"254.6","Tissue RNA - adrenal gland [nTPM]":"59.8","Tissue RNA - amygdala [nTPM]":"2.6","Tissue RNA - appendix [nTPM]":"62.3","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"53.7","Tissue RNA - breast [nTPM]":"115.8","Tissue RNA - cerebellum [nTPM]":"3.7","Tissue RNA - cerebral cortex [nTPM]":"3.3","Tissue RNA - cervix [nTPM]":"54.4","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"57.9","Tissue RNA - duodenum [nTPM]":"30.6","Tissue RNA - endometrium 1 [nTPM]":"53.8","Tissue RNA - epididymis [nTPM]":"3.8","Tissue RNA - esophagus [nTPM]":"99.5","Tissue RNA - fallopian tube [nTPM]":"167.5","Tissue RNA - gallbladder [nTPM]":"83.3","Tissue RNA - heart muscle [nTPM]":"45.5","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"6.3","Tissue RNA - kidney [nTPM]":"20.0","Tissue RNA - liver [nTPM]":"64.9","Tissue RNA - lung [nTPM]":"47.0","Tissue RNA - lymph node [nTPM]":"49.4","Tissue RNA - medulla oblongata [nTPM]":"9.2","Tissue RNA - midbrain [nTPM]":"5.0","Tissue RNA - ovary [nTPM]":"100.0","Tissue RNA - pancreas [nTPM]":"103.1","Tissue RNA - parathyroid gland [nTPM]":"7.0","Tissue RNA - pituitary gland [nTPM]":"12.3","Tissue RNA - placenta [nTPM]":"33.4","Tissue RNA - pons [nTPM]":"6.0","Tissue RNA - prostate [nTPM]":"32.7","Tissue RNA - rectum [nTPM]":"36.8","Tissue RNA - retina [nTPM]":"0.7","Tissue RNA - salivary gland [nTPM]":"42.2","Tissue RNA - seminal vesicle [nTPM]":"14.1","Tissue RNA - skeletal muscle [nTPM]":"50.6","Tissue RNA - skin 1 [nTPM]":"289.1","Tissue RNA - small intestine [nTPM]":"48.6","Tissue RNA - smooth muscle [nTPM]":"54.8","Tissue RNA - spinal cord [nTPM]":"4.5","Tissue RNA - spleen [nTPM]":"60.1","Tissue RNA - stomach 1 [nTPM]":"70.6","Tissue RNA - testis [nTPM]":"12.5","Tissue RNA - thalamus [nTPM]":"5.5","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"27.0","Tissue RNA - tongue [nTPM]":"15.7","Tissue RNA - tonsil [nTPM]":"39.2","Tissue RNA - urinary bladder [nTPM]":"63.2","Tissue RNA - vagina [nTPM]":"96.3","Tissue RNA - white matter [nTPM]":"4.4","Cell RNA - A-431 [nTPM]":"56.8","Cell RNA - A549 [nTPM]":"89.3","Cell RNA - AF22 [nTPM]":"9.3","Cell RNA - AN3-CA [nTPM]":"100.9","Cell RNA - ASC diff [nTPM]":"166.6","Cell RNA - ASC TERT1 [nTPM]":"209.8","Cell RNA - BEWO [nTPM]":"28.4","Cell RNA - BJ [nTPM]":"72.2","Cell RNA - BJ hTERT+ [nTPM]":"31.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.7","Cell RNA - CACO-2 [nTPM]":"137.0","Cell RNA - CAPAN-2 [nTPM]":"150.2","Cell RNA - Daudi [nTPM]":"587.3","Cell RNA - EFO-21 [nTPM]":"86.4","Cell RNA - fHDF\/TERT166 [nTPM]":"43.0","Cell RNA - GAMG [nTPM]":"82.4","Cell RNA - HaCaT [nTPM]":"122.2","Cell RNA - HAP1 [nTPM]":"383.8","Cell RNA - HBEC3-KT [nTPM]":"226.5","Cell RNA - HBF TERT88 [nTPM]":"67.8","Cell RNA - HDLM-2 [nTPM]":"128.9","Cell RNA - HEK 293 [nTPM]":"167.0","Cell RNA - HEL [nTPM]":"370.7","Cell RNA - HeLa [nTPM]":"189.5","Cell RNA - Hep G2 [nTPM]":"203.6","Cell RNA - HHSteC [nTPM]":"150.0","Cell RNA - HL-60 [nTPM]":"282.0","Cell RNA - HMC-1 [nTPM]":"52.0","Cell RNA - HSkMC [nTPM]":"138.8","Cell RNA - hTCEpi [nTPM]":"560.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"55.5","Cell RNA - hTERT-HME1 [nTPM]":"490.8","Cell RNA - hTERT-RPE1 [nTPM]":"74.8","Cell RNA - HUVEC TERT2 [nTPM]":"104.3","Cell RNA - JURKAT [nTPM]":"217.3","Cell RNA - K-562 [nTPM]":"549.8","Cell RNA - Karpas-707 [nTPM]":"315.5","Cell RNA - LHCN-M2 [nTPM]":"49.7","Cell RNA - MCF7 [nTPM]":"151.9","Cell RNA - MOLT-4 [nTPM]":"394.4","Cell RNA - NB-4 [nTPM]":"616.9","Cell RNA - NTERA-2 [nTPM]":"27.4","Cell RNA - OE19 [nTPM]":"273.2","Cell RNA - PC-3 [nTPM]":"204.0","Cell RNA - REH [nTPM]":"203.7","Cell RNA - RH-30 [nTPM]":"46.1","Cell RNA - RPMI-8226 [nTPM]":"1069.6","Cell RNA - RPTEC TERT1 [nTPM]":"79.2","Cell RNA - RT4 [nTPM]":"61.9","Cell RNA - SCLC-21H [nTPM]":"660.7","Cell RNA - SH-SY5Y [nTPM]":"64.9","Cell RNA - SiHa [nTPM]":"32.6","Cell RNA - SK-BR-3 [nTPM]":"270.7","Cell RNA - SK-MEL-30 [nTPM]":"195.9","Cell RNA - SuSa [nTPM]":"17.5","Cell RNA - T-47d [nTPM]":"106.4","Cell RNA - THP-1 [nTPM]":"172.2","Cell RNA - TIME [nTPM]":"120.5","Cell RNA - U-138 MG [nTPM]":"63.4","Cell RNA - U-2 OS [nTPM]":"71.6","Cell RNA - U-2197 [nTPM]":"49.7","Cell RNA - U-251 MG [nTPM]":"87.2","Cell RNA - U-266\/70 [nTPM]":"5.5","Cell RNA - U-266\/84 [nTPM]":"8.7","Cell RNA - U-698 [nTPM]":"275.9","Cell RNA - U-87 MG [nTPM]":"55.3","Cell RNA - U-937 [nTPM]":"286.2","Cell RNA - WM-115 [nTPM]":"30.8","Blood RNA - basophil [nTPM]":"3.0","Blood RNA - classical monocyte [nTPM]":"39.5","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"31.5","Blood RNA - intermediate monocyte [nTPM]":"36.0","Blood RNA - MAIT T-cell [nTPM]":"161.5","Blood RNA - memory B-cell [nTPM]":"92.0","Blood RNA - memory CD4 T-cell [nTPM]":"114.3","Blood RNA - memory CD8 T-cell [nTPM]":"67.4","Blood RNA - myeloid DC [nTPM]":"33.5","Blood RNA - naive B-cell [nTPM]":"71.4","Blood RNA - naive CD4 T-cell [nTPM]":"195.2","Blood RNA - naive CD8 T-cell [nTPM]":"128.0","Blood RNA - neutrophil [nTPM]":"4.1","Blood RNA - NK-cell [nTPM]":"85.5","Blood RNA - non-classical monocyte [nTPM]":"26.9","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"95.6","Blood RNA - total PBMC [nTPM]":"88.9","Brain RNA - amygdala [nTPM]":"2.6","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"3.7","Brain RNA - cerebral cortex [nTPM]":"3.3","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"6.3","Brain RNA - medulla oblongata [nTPM]":"9.2","Brain RNA - midbrain [nTPM]":"5.0","Brain RNA - pons [nTPM]":"6.0","Brain RNA - spinal cord [nTPM]":"4.5","Brain RNA - thalamus [nTPM]":"5.5","Brain RNA - white matter [nTPM]":"4.4","Single Cell Type RNA - Adipocytes [nTPM]":"218.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"57.7","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"70.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"108.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1013.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1080.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"278.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1270.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"251.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"207.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"44.3","Single Cell Type RNA - Club cells [nTPM]":"98.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.6","Single Cell Type RNA - dendritic cells [nTPM]":"20.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"23.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"78.3","Single Cell Type RNA - Early spermatids [nTPM]":"1.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"43.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"224.5","Single Cell Type RNA - Endothelial cells [nTPM]":"158.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"189.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"61.2","Single Cell Type RNA - Fibroblasts [nTPM]":"337.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"72.0","Single Cell Type RNA - granulocytes [nTPM]":"57.0","Single Cell Type RNA - Granulosa cells [nTPM]":"47.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"141.0","Single Cell Type RNA - Hepatocytes [nTPM]":"25.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"67.8","Single Cell Type RNA - Ionocytes [nTPM]":"97.6","Single Cell Type RNA - Kupffer cells [nTPM]":"43.7","Single Cell Type RNA - Langerhans cells [nTPM]":"133.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"98.8","Single Cell Type RNA - Macrophages [nTPM]":"23.3","Single Cell Type RNA - Melanocytes [nTPM]":"168.9","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"17.0","Single Cell Type RNA - Muller glia cells [nTPM]":"1.4","Single Cell Type RNA - NK-cells [nTPM]":"5.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"66.5","Single Cell Type RNA - Paneth cells [nTPM]":"40.4","Single Cell Type RNA - Peritubular cells [nTPM]":"67.4","Single Cell Type RNA - Plasma cells [nTPM]":"45.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"364.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"21.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"458.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"349.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"768.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1070.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.9","Single Cell Type RNA - T-cells [nTPM]":"75.0","Single Cell Type RNA - Theca cells [nTPM]":"56.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"117.7","Single Cell Type RNA - Urothelial cells [nTPM]":"409.4"},{"Gene":"MYCN","Gene synonym":["bHLHe37","MYCNOT","N-myc","NMYC"],"Ensembl":"ENSG00000134323","Gene description":"MYCN proto-oncogene, bHLH transcription factor","Uniprot":["P04198"],"Chromosome":"2","Position":"15940550-15947007","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"placenta":"9.5"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"84.2","Granulosa cells":"26.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"testis cancer":"45.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"44.1","BEWO":"239.1","HMC-1":"57.3","NTERA-2":"91.3","RH-30":"63.3","SuSa":"40.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA057420"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA057420":"AB_2683434"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.11e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.47e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.90e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.4","Tissue RNA - adrenal gland [nTPM]":"0.8","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"3.5","Tissue RNA - bone marrow [nTPM]":"0.9","Tissue RNA - breast [nTPM]":"0.4","Tissue RNA - cerebellum [nTPM]":"3.1","Tissue RNA - cerebral cortex [nTPM]":"3.9","Tissue RNA - cervix [nTPM]":"1.5","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"0.6","Tissue RNA - duodenum [nTPM]":"1.6","Tissue RNA - endometrium 1 [nTPM]":"0.9","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.3","Tissue RNA - heart muscle [nTPM]":"1.2","Tissue RNA - hippocampal formation [nTPM]":"3.4","Tissue RNA - hypothalamus [nTPM]":"3.0","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"0.8","Tissue RNA - lung [nTPM]":"0.7","Tissue RNA - lymph node [nTPM]":"1.6","Tissue RNA - medulla oblongata [nTPM]":"4.4","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"9.5","Tissue RNA - pons [nTPM]":"3.7","Tissue RNA - prostate [nTPM]":"0.1","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"1.4","Tissue RNA - small intestine [nTPM]":"0.9","Tissue RNA - smooth muscle [nTPM]":"0.3","Tissue RNA - spinal cord [nTPM]":"3.3","Tissue RNA - spleen [nTPM]":"0.3","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"3.6","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"2.9","Tissue RNA - thyroid gland [nTPM]":"2.9","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"1.2","Tissue RNA - urinary bladder [nTPM]":"0.5","Tissue RNA - vagina [nTPM]":"0.4","Tissue RNA - white matter [nTPM]":"5.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"44.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"239.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"3.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.9","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"16.8","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"57.3","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.2","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"91.3","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"63.3","Cell RNA - RPMI-8226 [nTPM]":"12.8","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"3.1","Cell RNA - SCLC-21H [nTPM]":"1.0","Cell RNA - SH-SY5Y [nTPM]":"16.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"40.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.2","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"2.9","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"3.5","Brain RNA - cerebellum [nTPM]":"3.1","Brain RNA - cerebral cortex [nTPM]":"3.9","Brain RNA - hippocampal formation [nTPM]":"3.4","Brain RNA - hypothalamus [nTPM]":"3.0","Brain RNA - medulla oblongata [nTPM]":"4.4","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"3.7","Brain RNA - spinal cord [nTPM]":"3.3","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"5.9","Single Cell Type RNA - Adipocytes [nTPM]":"0.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"2.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"84.2","Single Cell Type RNA - Fibroblasts [nTPM]":"1.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"26.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.9","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"1.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.7","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"11.5","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"9.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"MYD88","Gene synonym":[],"Ensembl":"ENSG00000172936","Gene description":"MYD88 innate immune signal transduction adaptor","Uniprot":["Q99836"],"Chromosome":"3","Position":"38138478-38143022","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Immunity","Inflammatory response","Innate immunity"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Kupffer cells":"75.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-BR-3":"172.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009104"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 51: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 19: Monocytes & Neutrophils - Innate immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":["Vesicles","Mitochondria"],"Antibody RRID":{"CAB009104":"AB_2146724"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.45e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.77e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.38e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.28e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.08e-2"},"Tissue RNA - adipose tissue [nTPM]":"20.1","Tissue RNA - adrenal gland [nTPM]":"14.2","Tissue RNA - amygdala [nTPM]":"6.9","Tissue RNA - appendix [nTPM]":"43.5","Tissue RNA - basal ganglia [nTPM]":"7.4","Tissue RNA - bone marrow [nTPM]":"51.8","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"7.2","Tissue RNA - cerebral cortex [nTPM]":"7.5","Tissue RNA - cervix [nTPM]":"15.2","Tissue RNA - choroid plexus [nTPM]":"8.0","Tissue RNA - colon [nTPM]":"30.3","Tissue RNA - duodenum [nTPM]":"32.2","Tissue RNA - endometrium 1 [nTPM]":"12.1","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"36.6","Tissue RNA - fallopian tube [nTPM]":"14.4","Tissue RNA - gallbladder [nTPM]":"23.5","Tissue RNA - heart muscle [nTPM]":"9.4","Tissue RNA - hippocampal formation [nTPM]":"6.7","Tissue RNA - hypothalamus [nTPM]":"7.7","Tissue RNA - kidney [nTPM]":"13.7","Tissue RNA - liver [nTPM]":"61.1","Tissue RNA - lung [nTPM]":"42.6","Tissue RNA - lymph node [nTPM]":"35.2","Tissue RNA - medulla oblongata [nTPM]":"9.5","Tissue RNA - midbrain [nTPM]":"7.5","Tissue RNA - ovary [nTPM]":"11.4","Tissue RNA - pancreas [nTPM]":"11.6","Tissue RNA - parathyroid gland [nTPM]":"11.6","Tissue RNA - pituitary gland [nTPM]":"9.2","Tissue RNA - placenta [nTPM]":"22.6","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"14.3","Tissue RNA - rectum [nTPM]":"31.7","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"18.0","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"17.7","Tissue RNA - small intestine [nTPM]":"32.2","Tissue RNA - smooth muscle [nTPM]":"24.5","Tissue RNA - spinal cord [nTPM]":"8.6","Tissue RNA - spleen [nTPM]":"40.7","Tissue RNA - stomach 1 [nTPM]":"27.6","Tissue RNA - testis [nTPM]":"7.7","Tissue RNA - thalamus [nTPM]":"9.2","Tissue RNA - thymus [nTPM]":"38.3","Tissue RNA - thyroid gland [nTPM]":"9.4","Tissue RNA - tongue [nTPM]":"8.8","Tissue RNA - tonsil [nTPM]":"41.6","Tissue RNA - urinary bladder [nTPM]":"47.4","Tissue RNA - vagina [nTPM]":"20.3","Tissue RNA - white matter [nTPM]":"8.5","Cell RNA - A-431 [nTPM]":"25.1","Cell RNA - A549 [nTPM]":"34.2","Cell RNA - AF22 [nTPM]":"5.9","Cell RNA - AN3-CA [nTPM]":"33.2","Cell RNA - ASC diff [nTPM]":"25.0","Cell RNA - ASC TERT1 [nTPM]":"32.0","Cell RNA - BEWO [nTPM]":"10.8","Cell RNA - BJ [nTPM]":"23.6","Cell RNA - BJ hTERT+ [nTPM]":"39.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"68.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"72.9","Cell RNA - CACO-2 [nTPM]":"22.7","Cell RNA - CAPAN-2 [nTPM]":"30.9","Cell RNA - Daudi [nTPM]":"52.8","Cell RNA - EFO-21 [nTPM]":"13.8","Cell RNA - fHDF\/TERT166 [nTPM]":"44.7","Cell RNA - GAMG [nTPM]":"15.8","Cell RNA - HaCaT [nTPM]":"30.9","Cell RNA - HAP1 [nTPM]":"43.2","Cell RNA - HBEC3-KT [nTPM]":"24.2","Cell RNA - HBF TERT88 [nTPM]":"22.1","Cell RNA - HDLM-2 [nTPM]":"39.5","Cell RNA - HEK 293 [nTPM]":"8.7","Cell RNA - HEL [nTPM]":"28.5","Cell RNA - HeLa [nTPM]":"16.6","Cell RNA - Hep G2 [nTPM]":"36.6","Cell RNA - HHSteC [nTPM]":"21.4","Cell RNA - HL-60 [nTPM]":"36.2","Cell RNA - HMC-1 [nTPM]":"72.0","Cell RNA - HSkMC [nTPM]":"38.4","Cell RNA - hTCEpi [nTPM]":"26.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.2","Cell RNA - hTERT-HME1 [nTPM]":"15.3","Cell RNA - hTERT-RPE1 [nTPM]":"13.2","Cell RNA - HUVEC TERT2 [nTPM]":"39.9","Cell RNA - JURKAT [nTPM]":"40.3","Cell RNA - K-562 [nTPM]":"13.3","Cell RNA - Karpas-707 [nTPM]":"22.3","Cell RNA - LHCN-M2 [nTPM]":"36.8","Cell RNA - MCF7 [nTPM]":"25.7","Cell RNA - MOLT-4 [nTPM]":"61.3","Cell RNA - NB-4 [nTPM]":"12.2","Cell RNA - NTERA-2 [nTPM]":"22.1","Cell RNA - OE19 [nTPM]":"52.8","Cell RNA - PC-3 [nTPM]":"35.7","Cell RNA - REH [nTPM]":"24.8","Cell RNA - RH-30 [nTPM]":"7.0","Cell RNA - RPMI-8226 [nTPM]":"23.1","Cell RNA - RPTEC TERT1 [nTPM]":"37.6","Cell RNA - RT4 [nTPM]":"58.9","Cell RNA - SCLC-21H [nTPM]":"3.0","Cell RNA - SH-SY5Y [nTPM]":"12.0","Cell RNA - SiHa [nTPM]":"33.4","Cell RNA - SK-BR-3 [nTPM]":"172.1","Cell RNA - SK-MEL-30 [nTPM]":"22.3","Cell RNA - SuSa [nTPM]":"4.8","Cell RNA - T-47d [nTPM]":"25.8","Cell RNA - THP-1 [nTPM]":"40.8","Cell RNA - TIME [nTPM]":"35.5","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"7.9","Cell RNA - U-2197 [nTPM]":"60.6","Cell RNA - U-251 MG [nTPM]":"24.0","Cell RNA - U-266\/70 [nTPM]":"28.9","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"38.5","Cell RNA - U-87 MG [nTPM]":"25.0","Cell RNA - U-937 [nTPM]":"63.0","Cell RNA - WM-115 [nTPM]":"28.9","Blood RNA - basophil [nTPM]":"288.5","Blood RNA - classical monocyte [nTPM]":"236.9","Blood RNA - eosinophil [nTPM]":"296.9","Blood RNA - gdT-cell [nTPM]":"67.2","Blood RNA - intermediate monocyte [nTPM]":"333.6","Blood RNA - MAIT T-cell [nTPM]":"58.1","Blood RNA - memory B-cell [nTPM]":"43.7","Blood RNA - memory CD4 T-cell [nTPM]":"60.6","Blood RNA - memory CD8 T-cell [nTPM]":"69.3","Blood RNA - myeloid DC [nTPM]":"203.6","Blood RNA - naive B-cell [nTPM]":"35.2","Blood RNA - naive CD4 T-cell [nTPM]":"42.1","Blood RNA - naive CD8 T-cell [nTPM]":"59.5","Blood RNA - neutrophil [nTPM]":"284.7","Blood RNA - NK-cell [nTPM]":"54.6","Blood RNA - non-classical monocyte [nTPM]":"436.1","Blood RNA - plasmacytoid DC [nTPM]":"99.9","Blood RNA - T-reg [nTPM]":"87.4","Blood RNA - total PBMC [nTPM]":"257.3","Brain RNA - amygdala [nTPM]":"6.9","Brain RNA - basal ganglia [nTPM]":"7.4","Brain RNA - cerebellum [nTPM]":"7.2","Brain RNA - cerebral cortex [nTPM]":"7.5","Brain RNA - hippocampal formation [nTPM]":"6.7","Brain RNA - hypothalamus [nTPM]":"7.7","Brain RNA - medulla oblongata [nTPM]":"9.5","Brain RNA - midbrain [nTPM]":"7.5","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"8.6","Brain RNA - thalamus [nTPM]":"9.2","Brain RNA - white matter [nTPM]":"8.5","Single Cell Type RNA - Adipocytes [nTPM]":"13.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.2","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"19.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"13.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"10.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"16.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"14.6","Single Cell Type RNA - dendritic cells [nTPM]":"35.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"24.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"30.2","Single Cell Type RNA - Endothelial cells [nTPM]":"15.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"27.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"24.4","Single Cell Type RNA - Fibroblasts [nTPM]":"10.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"23.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"18.6","Single Cell Type RNA - granulocytes [nTPM]":"24.1","Single Cell Type RNA - Granulosa cells [nTPM]":"10.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.4","Single Cell Type RNA - Hepatocytes [nTPM]":"33.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"32.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.9","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"75.4","Single Cell Type RNA - Langerhans cells [nTPM]":"40.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"61.5","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"1.9","Single Cell Type RNA - monocytes [nTPM]":"58.1","Single Cell Type RNA - Muller glia cells [nTPM]":"4.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"64.0","Single Cell Type RNA - Paneth cells [nTPM]":"34.8","Single Cell Type RNA - Peritubular cells [nTPM]":"10.5","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"12.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"7.2","Single Cell Type RNA - Spermatocytes [nTPM]":"8.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.0","Single Cell Type RNA - T-cells [nTPM]":"19.6","Single Cell Type RNA - Theca cells [nTPM]":"10.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.9","Single Cell Type RNA - Urothelial cells [nTPM]":"49.4"},{"Gene":"NAV3","Gene synonym":["KIAA0938","POMFIL1"],"Ensembl":"ENSG00000067798","Gene description":"Neuron navigator 3","Uniprot":["Q8IVL0"],"Chromosome":"12","Position":"77324641-78213010","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"17.3","ovary":"18.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Astrocytes":"882.1","Excitatory neurons":"1473.6","Inhibitory neurons":"753.8","Microglial cells":"534.0","Oligodendrocyte precursor cells":"786.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"8","RNA brain regional specific nTPM":{"amygdala":"9.7","basal ganglia":"15.0","cerebral cortex":"17.3","hippocampal formation":"13.6","white matter":"10.3"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"1.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"1.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"hTEC\/SVTERT24-B":"47.0","THP-1":"41.8","U-138 MG":"30.8","WM-115":"38.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA032111","HPA061392"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA032111":"AB_10603881","HPA061392":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.98e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.68e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.86e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-3"},"Tissue RNA - adipose tissue [nTPM]":"3.8","Tissue RNA - adrenal gland [nTPM]":"4.8","Tissue RNA - amygdala [nTPM]":"9.7","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"4.0","Tissue RNA - cerebellum [nTPM]":"0.9","Tissue RNA - cerebral cortex [nTPM]":"17.3","Tissue RNA - cervix [nTPM]":"1.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"1.7","Tissue RNA - duodenum [nTPM]":"0.3","Tissue RNA - endometrium 1 [nTPM]":"2.0","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"1.9","Tissue RNA - fallopian tube [nTPM]":"2.2","Tissue RNA - gallbladder [nTPM]":"5.1","Tissue RNA - heart muscle [nTPM]":"1.9","Tissue RNA - hippocampal formation [nTPM]":"13.6","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.4","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"3.3","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"0.7","Tissue RNA - midbrain [nTPM]":"0.4","Tissue RNA - ovary [nTPM]":"18.3","Tissue RNA - pancreas [nTPM]":"0.5","Tissue RNA - parathyroid gland [nTPM]":"0.4","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"2.2","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"0.9","Tissue RNA - seminal vesicle [nTPM]":"2.5","Tissue RNA - skeletal muscle [nTPM]":"1.3","Tissue RNA - skin 1 [nTPM]":"2.6","Tissue RNA - small intestine [nTPM]":"0.6","Tissue RNA - smooth muscle [nTPM]":"2.5","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"8.0","Tissue RNA - stomach 1 [nTPM]":"0.8","Tissue RNA - testis [nTPM]":"2.8","Tissue RNA - thalamus [nTPM]":"1.6","Tissue RNA - thymus [nTPM]":"1.9","Tissue RNA - thyroid gland [nTPM]":"1.2","Tissue RNA - tongue [nTPM]":"3.4","Tissue RNA - tonsil [nTPM]":"0.4","Tissue RNA - urinary bladder [nTPM]":"3.3","Tissue RNA - vagina [nTPM]":"1.7","Tissue RNA - white matter [nTPM]":"10.3","Cell RNA - A-431 [nTPM]":"3.5","Cell RNA - A549 [nTPM]":"8.7","Cell RNA - AF22 [nTPM]":"0.6","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"8.5","Cell RNA - ASC TERT1 [nTPM]":"18.1","Cell RNA - BEWO [nTPM]":"0.3","Cell RNA - BJ [nTPM]":"26.5","Cell RNA - BJ hTERT+ [nTPM]":"20.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.3","Cell RNA - CACO-2 [nTPM]":"1.7","Cell RNA - CAPAN-2 [nTPM]":"0.6","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"1.9","Cell RNA - fHDF\/TERT166 [nTPM]":"22.0","Cell RNA - GAMG [nTPM]":"7.2","Cell RNA - HaCaT [nTPM]":"2.5","Cell RNA - HAP1 [nTPM]":"7.8","Cell RNA - HBEC3-KT [nTPM]":"4.0","Cell RNA - HBF TERT88 [nTPM]":"19.3","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.2","Cell RNA - HeLa [nTPM]":"3.9","Cell RNA - Hep G2 [nTPM]":"0.2","Cell RNA - HHSteC [nTPM]":"6.7","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"6.2","Cell RNA - hTCEpi [nTPM]":"0.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.0","Cell RNA - hTERT-HME1 [nTPM]":"11.1","Cell RNA - hTERT-RPE1 [nTPM]":"9.3","Cell RNA - HUVEC TERT2 [nTPM]":"16.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"26.2","Cell RNA - MCF7 [nTPM]":"0.5","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"12.0","Cell RNA - NTERA-2 [nTPM]":"2.7","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"2.1","Cell RNA - REH [nTPM]":"1.0","Cell RNA - RH-30 [nTPM]":"2.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"1.7","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.6","Cell RNA - SK-BR-3 [nTPM]":"0.3","Cell RNA - SK-MEL-30 [nTPM]":"3.5","Cell RNA - SuSa [nTPM]":"0.8","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"41.8","Cell RNA - TIME [nTPM]":"14.1","Cell RNA - U-138 MG [nTPM]":"30.8","Cell RNA - U-2 OS [nTPM]":"8.1","Cell RNA - U-2197 [nTPM]":"12.0","Cell RNA - U-251 MG [nTPM]":"18.2","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"8.8","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"38.7","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.7","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"0.9","Brain RNA - cerebral cortex [nTPM]":"17.3","Brain RNA - hippocampal formation [nTPM]":"13.6","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.7","Brain RNA - midbrain [nTPM]":"0.4","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"1.6","Brain RNA - white matter [nTPM]":"10.3","Single Cell Type RNA - Adipocytes [nTPM]":"11.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"10.0","Single Cell Type RNA - Astrocytes [nTPM]":"882.1","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"5.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"7.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"4.2","Single Cell Type RNA - Early spermatids [nTPM]":"10.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1473.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"18.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.3","Single Cell Type RNA - granulocytes [nTPM]":"11.4","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"3.9","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.3","Single Cell Type RNA - Horizontal cells [nTPM]":"50.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"753.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"3.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.7","Single Cell Type RNA - Leydig cells [nTPM]":"23.9","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"534.0","Single Cell Type RNA - monocytes [nTPM]":"0.1","Single Cell Type RNA - Muller glia cells [nTPM]":"18.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"786.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"144.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"19.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"7.5","Single Cell Type RNA - Plasma cells [nTPM]":"1.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"1.3","Single Cell Type RNA - Theca cells [nTPM]":"73.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"2.9"},{"Gene":"NCOA4","Gene synonym":["ARA70","DKFZp762E1112","ELE1","PTC3","RFG"],"Ensembl":"ENSG00000266412","Gene description":"Nuclear receptor coactivator 4","Uniprot":["Q13772"],"Chromosome":"10","Position":"46005088-46030623","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Erythroid cells":"476.2","Macrophages":"316.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"dendritic cells":"251.9","granulocytes":"839.6","monocytes":"363.6"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA051260","HPA065208"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 51: Myeloid cells - Hemostasis","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA051260":"AB_2681412","HPA065208":"AB_2685432"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.44e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.26e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.34e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.04e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.78e-1"},"Tissue RNA - adipose tissue [nTPM]":"117.1","Tissue RNA - adrenal gland [nTPM]":"67.8","Tissue RNA - amygdala [nTPM]":"45.6","Tissue RNA - appendix [nTPM]":"91.5","Tissue RNA - basal ganglia [nTPM]":"52.5","Tissue RNA - bone marrow [nTPM]":"189.5","Tissue RNA - breast [nTPM]":"96.9","Tissue RNA - cerebellum [nTPM]":"56.1","Tissue RNA - cerebral cortex [nTPM]":"50.9","Tissue RNA - cervix [nTPM]":"85.1","Tissue RNA - choroid plexus [nTPM]":"50.7","Tissue RNA - colon [nTPM]":"110.3","Tissue RNA - duodenum [nTPM]":"249.7","Tissue RNA - endometrium 1 [nTPM]":"70.2","Tissue RNA - epididymis [nTPM]":"74.6","Tissue RNA - esophagus [nTPM]":"110.3","Tissue RNA - fallopian tube [nTPM]":"62.6","Tissue RNA - gallbladder [nTPM]":"87.8","Tissue RNA - heart muscle [nTPM]":"156.8","Tissue RNA - hippocampal formation [nTPM]":"40.6","Tissue RNA - hypothalamus [nTPM]":"55.8","Tissue RNA - kidney [nTPM]":"159.7","Tissue RNA - liver [nTPM]":"372.9","Tissue RNA - lung [nTPM]":"108.3","Tissue RNA - lymph node [nTPM]":"102.6","Tissue RNA - medulla oblongata [nTPM]":"52.4","Tissue RNA - midbrain [nTPM]":"53.5","Tissue RNA - ovary [nTPM]":"65.5","Tissue RNA - pancreas [nTPM]":"64.6","Tissue RNA - parathyroid gland [nTPM]":"97.9","Tissue RNA - pituitary gland [nTPM]":"25.2","Tissue RNA - placenta [nTPM]":"131.3","Tissue RNA - pons [nTPM]":"53.6","Tissue RNA - prostate [nTPM]":"132.2","Tissue RNA - rectum [nTPM]":"115.7","Tissue RNA - retina [nTPM]":"33.7","Tissue RNA - salivary gland [nTPM]":"79.2","Tissue RNA - seminal vesicle [nTPM]":"78.7","Tissue RNA - skeletal muscle [nTPM]":"163.5","Tissue RNA - skin 1 [nTPM]":"71.1","Tissue RNA - small intestine [nTPM]":"155.9","Tissue RNA - smooth muscle [nTPM]":"98.3","Tissue RNA - spinal cord [nTPM]":"52.6","Tissue RNA - spleen [nTPM]":"148.1","Tissue RNA - stomach 1 [nTPM]":"90.3","Tissue RNA - testis [nTPM]":"43.6","Tissue RNA - thalamus [nTPM]":"51.6","Tissue RNA - thymus [nTPM]":"124.4","Tissue RNA - thyroid gland [nTPM]":"87.0","Tissue RNA - tongue [nTPM]":"193.6","Tissue RNA - tonsil [nTPM]":"150.3","Tissue RNA - urinary bladder [nTPM]":"104.6","Tissue RNA - vagina [nTPM]":"46.8","Tissue RNA - white matter [nTPM]":"60.0","Cell RNA - A-431 [nTPM]":"142.7","Cell RNA - A549 [nTPM]":"58.5","Cell RNA - AF22 [nTPM]":"68.0","Cell RNA - AN3-CA [nTPM]":"70.4","Cell RNA - ASC diff [nTPM]":"176.9","Cell RNA - ASC TERT1 [nTPM]":"159.4","Cell RNA - BEWO [nTPM]":"170.3","Cell RNA - BJ [nTPM]":"128.3","Cell RNA - BJ hTERT+ [nTPM]":"204.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"122.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"119.6","Cell RNA - CACO-2 [nTPM]":"91.0","Cell RNA - CAPAN-2 [nTPM]":"102.3","Cell RNA - Daudi [nTPM]":"161.2","Cell RNA - EFO-21 [nTPM]":"149.2","Cell RNA - fHDF\/TERT166 [nTPM]":"211.2","Cell RNA - GAMG [nTPM]":"69.1","Cell RNA - HaCaT [nTPM]":"141.8","Cell RNA - HAP1 [nTPM]":"72.6","Cell RNA - HBEC3-KT [nTPM]":"142.3","Cell RNA - HBF TERT88 [nTPM]":"137.1","Cell RNA - HDLM-2 [nTPM]":"114.4","Cell RNA - HEK 293 [nTPM]":"74.1","Cell RNA - HEL [nTPM]":"108.4","Cell RNA - HeLa [nTPM]":"74.3","Cell RNA - Hep G2 [nTPM]":"263.5","Cell RNA - HHSteC [nTPM]":"124.0","Cell RNA - HL-60 [nTPM]":"279.9","Cell RNA - HMC-1 [nTPM]":"229.7","Cell RNA - HSkMC [nTPM]":"156.1","Cell RNA - hTCEpi [nTPM]":"139.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"104.2","Cell RNA - hTERT-HME1 [nTPM]":"175.7","Cell RNA - hTERT-RPE1 [nTPM]":"131.6","Cell RNA - HUVEC TERT2 [nTPM]":"185.5","Cell RNA - JURKAT [nTPM]":"79.5","Cell RNA - K-562 [nTPM]":"119.7","Cell RNA - Karpas-707 [nTPM]":"93.5","Cell RNA - LHCN-M2 [nTPM]":"171.9","Cell RNA - MCF7 [nTPM]":"64.0","Cell RNA - MOLT-4 [nTPM]":"136.1","Cell RNA - NB-4 [nTPM]":"104.3","Cell RNA - NTERA-2 [nTPM]":"41.4","Cell RNA - OE19 [nTPM]":"110.2","Cell RNA - PC-3 [nTPM]":"34.8","Cell RNA - REH [nTPM]":"79.5","Cell RNA - RH-30 [nTPM]":"99.3","Cell RNA - RPMI-8226 [nTPM]":"96.7","Cell RNA - RPTEC TERT1 [nTPM]":"148.9","Cell RNA - RT4 [nTPM]":"119.4","Cell RNA - SCLC-21H [nTPM]":"68.2","Cell RNA - SH-SY5Y [nTPM]":"46.1","Cell RNA - SiHa [nTPM]":"128.9","Cell RNA - SK-BR-3 [nTPM]":"146.2","Cell RNA - SK-MEL-30 [nTPM]":"131.5","Cell RNA - SuSa [nTPM]":"133.5","Cell RNA - T-47d [nTPM]":"105.7","Cell RNA - THP-1 [nTPM]":"135.3","Cell RNA - TIME [nTPM]":"171.6","Cell RNA - U-138 MG [nTPM]":"75.8","Cell RNA - U-2 OS [nTPM]":"89.9","Cell RNA - U-2197 [nTPM]":"81.3","Cell RNA - U-251 MG [nTPM]":"87.5","Cell RNA - U-266\/70 [nTPM]":"69.3","Cell RNA - U-266\/84 [nTPM]":"79.1","Cell RNA - U-698 [nTPM]":"156.9","Cell RNA - U-87 MG [nTPM]":"94.6","Cell RNA - U-937 [nTPM]":"231.2","Cell RNA - WM-115 [nTPM]":"41.2","Blood RNA - basophil [nTPM]":"692.1","Blood RNA - classical monocyte [nTPM]":"363.6","Blood RNA - eosinophil [nTPM]":"611.8","Blood RNA - gdT-cell [nTPM]":"78.9","Blood RNA - intermediate monocyte [nTPM]":"223.6","Blood RNA - MAIT T-cell [nTPM]":"86.2","Blood RNA - memory B-cell [nTPM]":"57.6","Blood RNA - memory CD4 T-cell [nTPM]":"73.3","Blood RNA - memory CD8 T-cell [nTPM]":"74.9","Blood RNA - myeloid DC [nTPM]":"251.9","Blood RNA - naive B-cell [nTPM]":"53.8","Blood RNA - naive CD4 T-cell [nTPM]":"78.2","Blood RNA - naive CD8 T-cell [nTPM]":"66.4","Blood RNA - neutrophil [nTPM]":"839.6","Blood RNA - NK-cell [nTPM]":"119.0","Blood RNA - non-classical monocyte [nTPM]":"275.3","Blood RNA - plasmacytoid DC [nTPM]":"77.4","Blood RNA - T-reg [nTPM]":"92.8","Blood RNA - total PBMC [nTPM]":"559.4","Brain RNA - amygdala [nTPM]":"45.6","Brain RNA - basal ganglia [nTPM]":"52.5","Brain RNA - cerebellum [nTPM]":"56.1","Brain RNA - cerebral cortex [nTPM]":"50.9","Brain RNA - hippocampal formation [nTPM]":"40.6","Brain RNA - hypothalamus [nTPM]":"55.8","Brain RNA - medulla oblongata [nTPM]":"52.4","Brain RNA - midbrain [nTPM]":"53.5","Brain RNA - pons [nTPM]":"53.6","Brain RNA - spinal cord [nTPM]":"52.6","Brain RNA - thalamus [nTPM]":"51.6","Brain RNA - white matter [nTPM]":"60.0","Single Cell Type RNA - Adipocytes [nTPM]":"44.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"51.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"95.2","Single Cell Type RNA - Astrocytes [nTPM]":"13.4","Single Cell Type RNA - B-cells [nTPM]":"44.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"49.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"126.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Bipolar cells [nTPM]":"14.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"38.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"161.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"45.8","Single Cell Type RNA - Club cells [nTPM]":"96.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"44.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"104.7","Single Cell Type RNA - dendritic cells [nTPM]":"58.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"108.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"80.3","Single Cell Type RNA - Ductal cells [nTPM]":"45.3","Single Cell Type RNA - Early spermatids [nTPM]":"105.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"45.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"37.7","Single Cell Type RNA - Endothelial cells [nTPM]":"52.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.9","Single Cell Type RNA - Erythroid cells [nTPM]":"476.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"107.2","Single Cell Type RNA - Fibroblasts [nTPM]":"45.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"42.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"56.9","Single Cell Type RNA - granulocytes [nTPM]":"195.2","Single Cell Type RNA - Granulosa cells [nTPM]":"28.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"55.3","Single Cell Type RNA - Hepatocytes [nTPM]":"166.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"181.4","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"45.4","Single Cell Type RNA - Ionocytes [nTPM]":"59.0","Single Cell Type RNA - Kupffer cells [nTPM]":"254.5","Single Cell Type RNA - Langerhans cells [nTPM]":"74.2","Single Cell Type RNA - Late spermatids [nTPM]":"72.4","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"316.1","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"16.9","Single Cell Type RNA - monocytes [nTPM]":"158.4","Single Cell Type RNA - Muller glia cells [nTPM]":"38.2","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"22.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"47.8","Single Cell Type RNA - Paneth cells [nTPM]":"63.9","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"37.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"62.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"162.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"128.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"36.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"46.7","Single Cell Type RNA - Spermatocytes [nTPM]":"24.5","Single Cell Type RNA - Spermatogonia [nTPM]":"16.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"71.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"56.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"158.2","Single Cell Type RNA - T-cells [nTPM]":"41.3","Single Cell Type RNA - Theca cells [nTPM]":"60.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"71.3","Single Cell Type RNA - Urothelial cells [nTPM]":"52.0"},{"Gene":"NF1","Gene synonym":[],"Ensembl":"ENSG00000196712","Gene description":"Neurofibromin 1","Uniprot":["P21359"],"Chromosome":"17","Position":"31094927-31382116","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"254.0","Excitatory neurons":"325.3","Inhibitory neurons":"412.5","Oligodendrocyte precursor cells":"428.2","Oligodendrocytes":"317.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045502"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 21: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA045502":"AB_2679352"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.73e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"7.4","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"3.4","Tissue RNA - breast [nTPM]":"11.5","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"12.2","Tissue RNA - cervix [nTPM]":"10.0","Tissue RNA - choroid plexus [nTPM]":"1.6","Tissue RNA - colon [nTPM]":"8.5","Tissue RNA - duodenum [nTPM]":"6.8","Tissue RNA - endometrium 1 [nTPM]":"10.2","Tissue RNA - epididymis [nTPM]":"10.0","Tissue RNA - esophagus [nTPM]":"6.1","Tissue RNA - fallopian tube [nTPM]":"9.0","Tissue RNA - gallbladder [nTPM]":"8.0","Tissue RNA - heart muscle [nTPM]":"11.3","Tissue RNA - hippocampal formation [nTPM]":"9.7","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"12.0","Tissue RNA - liver [nTPM]":"9.4","Tissue RNA - lung [nTPM]":"7.3","Tissue RNA - lymph node [nTPM]":"7.7","Tissue RNA - medulla oblongata [nTPM]":"11.7","Tissue RNA - midbrain [nTPM]":"9.2","Tissue RNA - ovary [nTPM]":"13.5","Tissue RNA - pancreas [nTPM]":"10.4","Tissue RNA - parathyroid gland [nTPM]":"15.9","Tissue RNA - pituitary gland [nTPM]":"7.8","Tissue RNA - placenta [nTPM]":"12.4","Tissue RNA - pons [nTPM]":"9.1","Tissue RNA - prostate [nTPM]":"9.5","Tissue RNA - rectum [nTPM]":"8.8","Tissue RNA - retina [nTPM]":"20.9","Tissue RNA - salivary gland [nTPM]":"9.1","Tissue RNA - seminal vesicle [nTPM]":"9.5","Tissue RNA - skeletal muscle [nTPM]":"8.1","Tissue RNA - skin 1 [nTPM]":"7.4","Tissue RNA - small intestine [nTPM]":"7.5","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"8.2","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"8.2","Tissue RNA - testis [nTPM]":"10.0","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"13.5","Tissue RNA - thyroid gland [nTPM]":"19.5","Tissue RNA - tongue [nTPM]":"10.6","Tissue RNA - tonsil [nTPM]":"7.8","Tissue RNA - urinary bladder [nTPM]":"10.4","Tissue RNA - vagina [nTPM]":"6.8","Tissue RNA - white matter [nTPM]":"14.4","Cell RNA - A-431 [nTPM]":"15.8","Cell RNA - A549 [nTPM]":"20.3","Cell RNA - AF22 [nTPM]":"24.2","Cell RNA - AN3-CA [nTPM]":"13.1","Cell RNA - ASC diff [nTPM]":"20.1","Cell RNA - ASC TERT1 [nTPM]":"25.8","Cell RNA - BEWO [nTPM]":"12.2","Cell RNA - BJ [nTPM]":"13.4","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"19.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"21.8","Cell RNA - CACO-2 [nTPM]":"18.4","Cell RNA - CAPAN-2 [nTPM]":"10.5","Cell RNA - Daudi [nTPM]":"15.2","Cell RNA - EFO-21 [nTPM]":"3.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.1","Cell RNA - GAMG [nTPM]":"22.9","Cell RNA - HaCaT [nTPM]":"26.8","Cell RNA - HAP1 [nTPM]":"22.2","Cell RNA - HBEC3-KT [nTPM]":"18.7","Cell RNA - HBF TERT88 [nTPM]":"32.6","Cell RNA - HDLM-2 [nTPM]":"7.5","Cell RNA - HEK 293 [nTPM]":"14.1","Cell RNA - HEL [nTPM]":"13.4","Cell RNA - HeLa [nTPM]":"18.8","Cell RNA - Hep G2 [nTPM]":"9.5","Cell RNA - HHSteC [nTPM]":"14.2","Cell RNA - HL-60 [nTPM]":"24.4","Cell RNA - HMC-1 [nTPM]":"10.6","Cell RNA - HSkMC [nTPM]":"20.7","Cell RNA - hTCEpi [nTPM]":"11.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.8","Cell RNA - hTERT-HME1 [nTPM]":"25.1","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"9.5","Cell RNA - JURKAT [nTPM]":"15.7","Cell RNA - K-562 [nTPM]":"19.8","Cell RNA - Karpas-707 [nTPM]":"14.8","Cell RNA - LHCN-M2 [nTPM]":"18.8","Cell RNA - MCF7 [nTPM]":"12.4","Cell RNA - MOLT-4 [nTPM]":"20.4","Cell RNA - NB-4 [nTPM]":"8.8","Cell RNA - NTERA-2 [nTPM]":"7.1","Cell RNA - OE19 [nTPM]":"9.7","Cell RNA - PC-3 [nTPM]":"6.8","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"36.8","Cell RNA - RPMI-8226 [nTPM]":"12.3","Cell RNA - RPTEC TERT1 [nTPM]":"14.7","Cell RNA - RT4 [nTPM]":"22.5","Cell RNA - SCLC-21H [nTPM]":"10.0","Cell RNA - SH-SY5Y [nTPM]":"14.9","Cell RNA - SiHa [nTPM]":"25.4","Cell RNA - SK-BR-3 [nTPM]":"8.3","Cell RNA - SK-MEL-30 [nTPM]":"13.8","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"25.0","Cell RNA - THP-1 [nTPM]":"15.3","Cell RNA - TIME [nTPM]":"14.1","Cell RNA - U-138 MG [nTPM]":"15.3","Cell RNA - U-2 OS [nTPM]":"21.5","Cell RNA - U-2197 [nTPM]":"18.8","Cell RNA - U-251 MG [nTPM]":"5.1","Cell RNA - U-266\/70 [nTPM]":"13.2","Cell RNA - U-266\/84 [nTPM]":"6.9","Cell RNA - U-698 [nTPM]":"16.3","Cell RNA - U-87 MG [nTPM]":"12.6","Cell RNA - U-937 [nTPM]":"10.0","Cell RNA - WM-115 [nTPM]":"16.2","Blood RNA - basophil [nTPM]":"4.4","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.5","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"1.0","Blood RNA - memory B-cell [nTPM]":"1.4","Blood RNA - memory CD4 T-cell [nTPM]":"2.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"2.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"0.7","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"5.9","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"12.2","Brain RNA - hippocampal formation [nTPM]":"9.7","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"11.7","Brain RNA - midbrain [nTPM]":"9.2","Brain RNA - pons [nTPM]":"9.1","Brain RNA - spinal cord [nTPM]":"8.2","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"14.4","Single Cell Type RNA - Adipocytes [nTPM]":"30.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"31.1","Single Cell Type RNA - Astrocytes [nTPM]":"254.0","Single Cell Type RNA - B-cells [nTPM]":"18.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"48.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"31.9","Single Cell Type RNA - Bipolar cells [nTPM]":"62.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"33.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"43.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"29.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"40.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"137.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"57.5","Single Cell Type RNA - dendritic cells [nTPM]":"23.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"37.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"27.1","Single Cell Type RNA - Early spermatids [nTPM]":"210.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"39.4","Single Cell Type RNA - Endothelial cells [nTPM]":"35.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"19.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"325.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"22.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"26.6","Single Cell Type RNA - Fibroblasts [nTPM]":"39.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.8","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"44.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"35.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.5","Single Cell Type RNA - Horizontal cells [nTPM]":"70.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"412.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"24.3","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"27.6","Single Cell Type RNA - Langerhans cells [nTPM]":"34.1","Single Cell Type RNA - Late spermatids [nTPM]":"94.6","Single Cell Type RNA - Leydig cells [nTPM]":"37.3","Single Cell Type RNA - Macrophages [nTPM]":"28.2","Single Cell Type RNA - Melanocytes [nTPM]":"21.4","Single Cell Type RNA - Microglial cells [nTPM]":"215.5","Single Cell Type RNA - monocytes [nTPM]":"20.9","Single Cell Type RNA - Muller glia cells [nTPM]":"47.5","Single Cell Type RNA - NK-cells [nTPM]":"21.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"428.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"317.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.3","Single Cell Type RNA - Paneth cells [nTPM]":"43.0","Single Cell Type RNA - Peritubular cells [nTPM]":"50.4","Single Cell Type RNA - Plasma cells [nTPM]":"30.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"54.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"32.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"28.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"36.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.8","Single Cell Type RNA - Sertoli cells [nTPM]":"46.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"51.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"43.3","Single Cell Type RNA - Spermatocytes [nTPM]":"30.5","Single Cell Type RNA - Spermatogonia [nTPM]":"28.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"34.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"49.3","Single Cell Type RNA - T-cells [nTPM]":"19.8","Single Cell Type RNA - Theca cells [nTPM]":"36.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"27.4","Single Cell Type RNA - Urothelial cells [nTPM]":"64.5"},{"Gene":"NF2","Gene synonym":["ACN","BANF","merlin","SCH"],"Ensembl":"ENSG00000186575","Gene description":"Neurofibromin 2","Uniprot":["P35240"],"Chromosome":"22","Position":"29603556-29698598","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Deafness","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"77.1","Late spermatids":"121.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003097","CAB005385"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 27: Non-specific - Gene expression","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB005385":"AB_2298548","HPA003097":"AB_1079473"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.76e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.14e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.66e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.89e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.73e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-2"},"Tissue RNA - adipose tissue [nTPM]":"8.8","Tissue RNA - adrenal gland [nTPM]":"13.6","Tissue RNA - amygdala [nTPM]":"19.7","Tissue RNA - appendix [nTPM]":"8.4","Tissue RNA - basal ganglia [nTPM]":"17.2","Tissue RNA - bone marrow [nTPM]":"8.0","Tissue RNA - breast [nTPM]":"7.6","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"28.7","Tissue RNA - cervix [nTPM]":"8.9","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"10.8","Tissue RNA - duodenum [nTPM]":"6.2","Tissue RNA - endometrium 1 [nTPM]":"11.1","Tissue RNA - epididymis [nTPM]":"6.2","Tissue RNA - esophagus [nTPM]":"13.4","Tissue RNA - fallopian tube [nTPM]":"8.6","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"21.4","Tissue RNA - hippocampal formation [nTPM]":"27.3","Tissue RNA - hypothalamus [nTPM]":"13.9","Tissue RNA - kidney [nTPM]":"17.2","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"9.3","Tissue RNA - lymph node [nTPM]":"6.4","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"18.1","Tissue RNA - ovary [nTPM]":"8.5","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"27.4","Tissue RNA - pituitary gland [nTPM]":"9.5","Tissue RNA - placenta [nTPM]":"4.6","Tissue RNA - pons [nTPM]":"14.3","Tissue RNA - prostate [nTPM]":"9.9","Tissue RNA - rectum [nTPM]":"5.4","Tissue RNA - retina [nTPM]":"7.3","Tissue RNA - salivary gland [nTPM]":"8.5","Tissue RNA - seminal vesicle [nTPM]":"6.7","Tissue RNA - skeletal muscle [nTPM]":"22.8","Tissue RNA - skin 1 [nTPM]":"10.2","Tissue RNA - small intestine [nTPM]":"8.8","Tissue RNA - smooth muscle [nTPM]":"8.0","Tissue RNA - spinal cord [nTPM]":"14.3","Tissue RNA - spleen [nTPM]":"9.9","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"20.9","Tissue RNA - thalamus [nTPM]":"17.6","Tissue RNA - thymus [nTPM]":"9.3","Tissue RNA - thyroid gland [nTPM]":"11.1","Tissue RNA - tongue [nTPM]":"19.1","Tissue RNA - tonsil [nTPM]":"7.1","Tissue RNA - urinary bladder [nTPM]":"9.3","Tissue RNA - vagina [nTPM]":"7.7","Tissue RNA - white matter [nTPM]":"16.6","Cell RNA - A-431 [nTPM]":"75.8","Cell RNA - A549 [nTPM]":"36.7","Cell RNA - AF22 [nTPM]":"12.2","Cell RNA - AN3-CA [nTPM]":"74.3","Cell RNA - ASC diff [nTPM]":"21.5","Cell RNA - ASC TERT1 [nTPM]":"22.0","Cell RNA - BEWO [nTPM]":"7.7","Cell RNA - BJ [nTPM]":"57.3","Cell RNA - BJ hTERT+ [nTPM]":"37.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"74.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"53.7","Cell RNA - CACO-2 [nTPM]":"32.7","Cell RNA - CAPAN-2 [nTPM]":"18.4","Cell RNA - Daudi [nTPM]":"21.1","Cell RNA - EFO-21 [nTPM]":"50.4","Cell RNA - fHDF\/TERT166 [nTPM]":"69.9","Cell RNA - GAMG [nTPM]":"48.9","Cell RNA - HaCaT [nTPM]":"27.1","Cell RNA - HAP1 [nTPM]":"25.1","Cell RNA - HBEC3-KT [nTPM]":"37.8","Cell RNA - HBF TERT88 [nTPM]":"52.0","Cell RNA - HDLM-2 [nTPM]":"31.9","Cell RNA - HEK 293 [nTPM]":"12.5","Cell RNA - HEL [nTPM]":"26.8","Cell RNA - HeLa [nTPM]":"24.4","Cell RNA - Hep G2 [nTPM]":"26.4","Cell RNA - HHSteC [nTPM]":"22.4","Cell RNA - HL-60 [nTPM]":"35.1","Cell RNA - HMC-1 [nTPM]":"28.6","Cell RNA - HSkMC [nTPM]":"20.1","Cell RNA - hTCEpi [nTPM]":"16.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"53.3","Cell RNA - hTERT-HME1 [nTPM]":"51.0","Cell RNA - hTERT-RPE1 [nTPM]":"21.8","Cell RNA - HUVEC TERT2 [nTPM]":"47.7","Cell RNA - JURKAT [nTPM]":"13.7","Cell RNA - K-562 [nTPM]":"12.0","Cell RNA - Karpas-707 [nTPM]":"18.7","Cell RNA - LHCN-M2 [nTPM]":"64.5","Cell RNA - MCF7 [nTPM]":"35.1","Cell RNA - MOLT-4 [nTPM]":"21.4","Cell RNA - NB-4 [nTPM]":"16.6","Cell RNA - NTERA-2 [nTPM]":"8.3","Cell RNA - OE19 [nTPM]":"16.9","Cell RNA - PC-3 [nTPM]":"20.4","Cell RNA - REH [nTPM]":"24.2","Cell RNA - RH-30 [nTPM]":"56.8","Cell RNA - RPMI-8226 [nTPM]":"18.8","Cell RNA - RPTEC TERT1 [nTPM]":"68.5","Cell RNA - RT4 [nTPM]":"37.3","Cell RNA - SCLC-21H [nTPM]":"17.0","Cell RNA - SH-SY5Y [nTPM]":"11.6","Cell RNA - SiHa [nTPM]":"36.0","Cell RNA - SK-BR-3 [nTPM]":"24.5","Cell RNA - SK-MEL-30 [nTPM]":"14.0","Cell RNA - SuSa [nTPM]":"9.4","Cell RNA - T-47d [nTPM]":"14.9","Cell RNA - THP-1 [nTPM]":"15.4","Cell RNA - TIME [nTPM]":"92.7","Cell RNA - U-138 MG [nTPM]":"101.1","Cell RNA - U-2 OS [nTPM]":"109.6","Cell RNA - U-2197 [nTPM]":"44.8","Cell RNA - U-251 MG [nTPM]":"112.5","Cell RNA - U-266\/70 [nTPM]":"30.0","Cell RNA - U-266\/84 [nTPM]":"26.7","Cell RNA - U-698 [nTPM]":"25.5","Cell RNA - U-87 MG [nTPM]":"27.0","Cell RNA - U-937 [nTPM]":"14.5","Cell RNA - WM-115 [nTPM]":"68.5","Blood RNA - basophil [nTPM]":"10.0","Blood RNA - classical monocyte [nTPM]":"10.0","Blood RNA - eosinophil [nTPM]":"4.2","Blood RNA - gdT-cell [nTPM]":"15.5","Blood RNA - intermediate monocyte [nTPM]":"14.7","Blood RNA - MAIT T-cell [nTPM]":"13.1","Blood RNA - memory B-cell [nTPM]":"8.3","Blood RNA - memory CD4 T-cell [nTPM]":"11.5","Blood RNA - memory CD8 T-cell [nTPM]":"10.4","Blood RNA - myeloid DC [nTPM]":"15.1","Blood RNA - naive B-cell [nTPM]":"8.6","Blood RNA - naive CD4 T-cell [nTPM]":"9.7","Blood RNA - naive CD8 T-cell [nTPM]":"9.2","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"13.2","Blood RNA - non-classical monocyte [nTPM]":"21.0","Blood RNA - plasmacytoid DC [nTPM]":"10.2","Blood RNA - T-reg [nTPM]":"10.7","Blood RNA - total PBMC [nTPM]":"12.2","Brain RNA - amygdala [nTPM]":"19.7","Brain RNA - basal ganglia [nTPM]":"17.2","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"28.7","Brain RNA - hippocampal formation [nTPM]":"27.3","Brain RNA - hypothalamus [nTPM]":"13.9","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"18.1","Brain RNA - pons [nTPM]":"14.3","Brain RNA - spinal cord [nTPM]":"14.3","Brain RNA - thalamus [nTPM]":"17.6","Brain RNA - white matter [nTPM]":"16.6","Single Cell Type RNA - Adipocytes [nTPM]":"8.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"20.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"9.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"16.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.7","Single Cell Type RNA - dendritic cells [nTPM]":"12.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"21.5","Single Cell Type RNA - Ductal cells [nTPM]":"40.0","Single Cell Type RNA - Early spermatids [nTPM]":"77.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"17.7","Single Cell Type RNA - Endothelial cells [nTPM]":"13.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"13.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"24.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"15.2","Single Cell Type RNA - granulocytes [nTPM]":"22.9","Single Cell Type RNA - Granulosa cells [nTPM]":"12.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.7","Single Cell Type RNA - Hepatocytes [nTPM]":"14.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.5","Single Cell Type RNA - Horizontal cells [nTPM]":"30.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"14.7","Single Cell Type RNA - Langerhans cells [nTPM]":"7.5","Single Cell Type RNA - Late spermatids [nTPM]":"121.4","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"10.2","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"8.6","Single Cell Type RNA - Muller glia cells [nTPM]":"19.1","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.1","Single Cell Type RNA - Paneth cells [nTPM]":"14.5","Single Cell Type RNA - Peritubular cells [nTPM]":"12.4","Single Cell Type RNA - Plasma cells [nTPM]":"14.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"9.6","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.6","Single Cell Type RNA - Spermatocytes [nTPM]":"29.5","Single Cell Type RNA - Spermatogonia [nTPM]":"8.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.8","Single Cell Type RNA - T-cells [nTPM]":"12.9","Single Cell Type RNA - Theca cells [nTPM]":"17.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"11.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.5"},{"Gene":"NFE2L2","Gene synonym":["NRF2"],"Ensembl":"ENSG00000116044","Gene description":"Nuclear factor, erythroid 2 like 2","Uniprot":["Q16236"],"Chromosome":"2","Position":"177227595-177392697","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002990","CAB020317","HPA043438"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Monocytes - Inflammatory response","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm","Plasma membrane"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB020317":null,"HPA002990":"AB_1079476","HPA043438":"AB_2678482"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.22e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.90e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.58e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.86e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.26e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.77e-3"},"Tissue RNA - adipose tissue [nTPM]":"87.0","Tissue RNA - adrenal gland [nTPM]":"73.6","Tissue RNA - amygdala [nTPM]":"64.8","Tissue RNA - appendix [nTPM]":"65.4","Tissue RNA - basal ganglia [nTPM]":"83.9","Tissue RNA - bone marrow [nTPM]":"58.9","Tissue RNA - breast [nTPM]":"78.3","Tissue RNA - cerebellum [nTPM]":"74.9","Tissue RNA - cerebral cortex [nTPM]":"86.7","Tissue RNA - cervix [nTPM]":"83.2","Tissue RNA - choroid plexus [nTPM]":"78.7","Tissue RNA - colon [nTPM]":"83.4","Tissue RNA - duodenum [nTPM]":"100.1","Tissue RNA - endometrium 1 [nTPM]":"92.6","Tissue RNA - epididymis [nTPM]":"97.2","Tissue RNA - esophagus [nTPM]":"257.0","Tissue RNA - fallopian tube [nTPM]":"88.5","Tissue RNA - gallbladder [nTPM]":"97.7","Tissue RNA - heart muscle [nTPM]":"77.6","Tissue RNA - hippocampal formation [nTPM]":"66.5","Tissue RNA - hypothalamus [nTPM]":"71.6","Tissue RNA - kidney [nTPM]":"143.5","Tissue RNA - liver [nTPM]":"176.6","Tissue RNA - lung [nTPM]":"88.5","Tissue RNA - lymph node [nTPM]":"50.4","Tissue RNA - medulla oblongata [nTPM]":"82.0","Tissue RNA - midbrain [nTPM]":"77.5","Tissue RNA - ovary [nTPM]":"137.3","Tissue RNA - pancreas [nTPM]":"47.3","Tissue RNA - parathyroid gland [nTPM]":"60.4","Tissue RNA - pituitary gland [nTPM]":"58.4","Tissue RNA - placenta [nTPM]":"80.4","Tissue RNA - pons [nTPM]":"84.5","Tissue RNA - prostate [nTPM]":"72.7","Tissue RNA - rectum [nTPM]":"85.8","Tissue RNA - retina [nTPM]":"68.2","Tissue RNA - salivary gland [nTPM]":"79.7","Tissue RNA - seminal vesicle [nTPM]":"90.5","Tissue RNA - skeletal muscle [nTPM]":"64.4","Tissue RNA - skin 1 [nTPM]":"162.3","Tissue RNA - small intestine [nTPM]":"82.9","Tissue RNA - smooth muscle [nTPM]":"91.8","Tissue RNA - spinal cord [nTPM]":"70.4","Tissue RNA - spleen [nTPM]":"69.0","Tissue RNA - stomach 1 [nTPM]":"176.9","Tissue RNA - testis [nTPM]":"65.2","Tissue RNA - thalamus [nTPM]":"75.7","Tissue RNA - thymus [nTPM]":"68.2","Tissue RNA - thyroid gland [nTPM]":"130.4","Tissue RNA - tongue [nTPM]":"65.9","Tissue RNA - tonsil [nTPM]":"93.8","Tissue RNA - urinary bladder [nTPM]":"160.7","Tissue RNA - vagina [nTPM]":"108.7","Tissue RNA - white matter [nTPM]":"91.8","Cell RNA - A-431 [nTPM]":"53.1","Cell RNA - A549 [nTPM]":"57.3","Cell RNA - AF22 [nTPM]":"52.2","Cell RNA - AN3-CA [nTPM]":"56.4","Cell RNA - ASC diff [nTPM]":"181.4","Cell RNA - ASC TERT1 [nTPM]":"190.2","Cell RNA - BEWO [nTPM]":"61.7","Cell RNA - BJ [nTPM]":"91.8","Cell RNA - BJ hTERT+ [nTPM]":"124.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"81.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"90.5","Cell RNA - CACO-2 [nTPM]":"75.9","Cell RNA - CAPAN-2 [nTPM]":"97.9","Cell RNA - Daudi [nTPM]":"52.8","Cell RNA - EFO-21 [nTPM]":"93.8","Cell RNA - fHDF\/TERT166 [nTPM]":"102.8","Cell RNA - GAMG [nTPM]":"148.4","Cell RNA - HaCaT [nTPM]":"96.9","Cell RNA - HAP1 [nTPM]":"65.1","Cell RNA - HBEC3-KT [nTPM]":"136.7","Cell RNA - HBF TERT88 [nTPM]":"111.5","Cell RNA - HDLM-2 [nTPM]":"40.8","Cell RNA - HEK 293 [nTPM]":"41.1","Cell RNA - HEL [nTPM]":"65.9","Cell RNA - HeLa [nTPM]":"95.9","Cell RNA - Hep G2 [nTPM]":"156.3","Cell RNA - HHSteC [nTPM]":"231.2","Cell RNA - HL-60 [nTPM]":"39.3","Cell RNA - HMC-1 [nTPM]":"60.6","Cell RNA - HSkMC [nTPM]":"134.0","Cell RNA - hTCEpi [nTPM]":"314.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"115.5","Cell RNA - hTERT-HME1 [nTPM]":"169.3","Cell RNA - hTERT-RPE1 [nTPM]":"184.4","Cell RNA - HUVEC TERT2 [nTPM]":"80.9","Cell RNA - JURKAT [nTPM]":"39.7","Cell RNA - K-562 [nTPM]":"72.7","Cell RNA - Karpas-707 [nTPM]":"91.4","Cell RNA - LHCN-M2 [nTPM]":"111.8","Cell RNA - MCF7 [nTPM]":"49.8","Cell RNA - MOLT-4 [nTPM]":"42.3","Cell RNA - NB-4 [nTPM]":"101.9","Cell RNA - NTERA-2 [nTPM]":"58.8","Cell RNA - OE19 [nTPM]":"277.2","Cell RNA - PC-3 [nTPM]":"58.9","Cell RNA - REH [nTPM]":"34.0","Cell RNA - RH-30 [nTPM]":"46.5","Cell RNA - RPMI-8226 [nTPM]":"54.6","Cell RNA - RPTEC TERT1 [nTPM]":"120.9","Cell RNA - RT4 [nTPM]":"182.1","Cell RNA - SCLC-21H [nTPM]":"69.0","Cell RNA - SH-SY5Y [nTPM]":"45.0","Cell RNA - SiHa [nTPM]":"202.9","Cell RNA - SK-BR-3 [nTPM]":"64.8","Cell RNA - SK-MEL-30 [nTPM]":"216.6","Cell RNA - SuSa [nTPM]":"147.8","Cell RNA - T-47d [nTPM]":"49.1","Cell RNA - THP-1 [nTPM]":"105.0","Cell RNA - TIME [nTPM]":"119.9","Cell RNA - U-138 MG [nTPM]":"80.4","Cell RNA - U-2 OS [nTPM]":"54.5","Cell RNA - U-2197 [nTPM]":"89.5","Cell RNA - U-251 MG [nTPM]":"54.7","Cell RNA - U-266\/70 [nTPM]":"70.1","Cell RNA - U-266\/84 [nTPM]":"44.7","Cell RNA - U-698 [nTPM]":"43.1","Cell RNA - U-87 MG [nTPM]":"81.6","Cell RNA - U-937 [nTPM]":"43.3","Cell RNA - WM-115 [nTPM]":"159.4","Blood RNA - basophil [nTPM]":"130.6","Blood RNA - classical monocyte [nTPM]":"89.3","Blood RNA - eosinophil [nTPM]":"55.4","Blood RNA - gdT-cell [nTPM]":"55.2","Blood RNA - intermediate monocyte [nTPM]":"84.3","Blood RNA - MAIT T-cell [nTPM]":"62.9","Blood RNA - memory B-cell [nTPM]":"61.8","Blood RNA - memory CD4 T-cell [nTPM]":"64.0","Blood RNA - memory CD8 T-cell [nTPM]":"57.0","Blood RNA - myeloid DC [nTPM]":"100.4","Blood RNA - naive B-cell [nTPM]":"51.9","Blood RNA - naive CD4 T-cell [nTPM]":"101.2","Blood RNA - naive CD8 T-cell [nTPM]":"66.8","Blood RNA - neutrophil [nTPM]":"103.2","Blood RNA - NK-cell [nTPM]":"68.1","Blood RNA - non-classical monocyte [nTPM]":"83.0","Blood RNA - plasmacytoid DC [nTPM]":"38.8","Blood RNA - T-reg [nTPM]":"66.6","Blood RNA - total PBMC [nTPM]":"66.0","Brain RNA - amygdala [nTPM]":"64.8","Brain RNA - basal ganglia [nTPM]":"83.9","Brain RNA - cerebellum [nTPM]":"74.9","Brain RNA - cerebral cortex [nTPM]":"86.7","Brain RNA - hippocampal formation [nTPM]":"66.5","Brain RNA - hypothalamus [nTPM]":"71.6","Brain RNA - medulla oblongata [nTPM]":"82.0","Brain RNA - midbrain [nTPM]":"77.5","Brain RNA - pons [nTPM]":"84.5","Brain RNA - spinal cord [nTPM]":"70.4","Brain RNA - thalamus [nTPM]":"75.7","Brain RNA - white matter [nTPM]":"91.8","Single Cell Type RNA - Adipocytes [nTPM]":"193.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"157.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"93.5","Single Cell Type RNA - Astrocytes [nTPM]":"66.3","Single Cell Type RNA - B-cells [nTPM]":"143.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"295.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"241.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"448.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"306.7","Single Cell Type RNA - Bipolar cells [nTPM]":"61.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"90.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"113.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"67.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"117.2","Single Cell Type RNA - Club cells [nTPM]":"247.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"154.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"113.2","Single Cell Type RNA - dendritic cells [nTPM]":"249.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"120.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"393.2","Single Cell Type RNA - Ductal cells [nTPM]":"154.5","Single Cell Type RNA - Early spermatids [nTPM]":"81.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"238.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"126.9","Single Cell Type RNA - Endothelial cells [nTPM]":"139.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"75.6","Single Cell Type RNA - Erythroid cells [nTPM]":"58.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"170.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"34.5","Single Cell Type RNA - Fibroblasts [nTPM]":"206.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"170.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"279.9","Single Cell Type RNA - granulocytes [nTPM]":"212.7","Single Cell Type RNA - Granulosa cells [nTPM]":"141.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"120.0","Single Cell Type RNA - Hepatocytes [nTPM]":"93.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.1","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"26.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"73.5","Single Cell Type RNA - Ionocytes [nTPM]":"321.4","Single Cell Type RNA - Kupffer cells [nTPM]":"111.6","Single Cell Type RNA - Langerhans cells [nTPM]":"569.9","Single Cell Type RNA - Late spermatids [nTPM]":"39.0","Single Cell Type RNA - Leydig cells [nTPM]":"287.7","Single Cell Type RNA - Macrophages [nTPM]":"266.0","Single Cell Type RNA - Melanocytes [nTPM]":"96.0","Single Cell Type RNA - Microglial cells [nTPM]":"88.1","Single Cell Type RNA - monocytes [nTPM]":"170.6","Single Cell Type RNA - Muller glia cells [nTPM]":"191.4","Single Cell Type RNA - NK-cells [nTPM]":"55.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"63.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"113.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"128.3","Single Cell Type RNA - Paneth cells [nTPM]":"91.8","Single Cell Type RNA - Peritubular cells [nTPM]":"214.0","Single Cell Type RNA - Plasma cells [nTPM]":"118.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"150.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"94.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"85.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"205.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"48.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"211.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"152.4","Single Cell Type RNA - Spermatocytes [nTPM]":"66.1","Single Cell Type RNA - Spermatogonia [nTPM]":"32.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"617.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"315.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"186.2","Single Cell Type RNA - T-cells [nTPM]":"150.6","Single Cell Type RNA - Theca cells [nTPM]":"153.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"119.6","Single Cell Type RNA - Urothelial cells [nTPM]":"225.2"},{"Gene":"NFKBIA","Gene synonym":["IkappaBalpha","IKBA","MAD-3","NFKBI"],"Ensembl":"ENSG00000100906","Gene description":"NFKB inhibitor alpha","Uniprot":["P25963"],"Chromosome":"14","Position":"35401513-35404749","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Ectodermal dysplasia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"1114.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"4056.6","Langerhans cells":"4828.7","Suprabasal keratinocytes":"3420.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RT4":"391.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003815","HPA029207"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 15: RT4 - Unknown function","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003815":"AB_344886","HPA029207":"AB_10603122"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.33e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.39e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.19e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.44e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"281.0","Tissue RNA - adrenal gland [nTPM]":"171.3","Tissue RNA - amygdala [nTPM]":"75.6","Tissue RNA - appendix [nTPM]":"150.7","Tissue RNA - basal ganglia [nTPM]":"78.0","Tissue RNA - bone marrow [nTPM]":"1114.7","Tissue RNA - breast [nTPM]":"171.4","Tissue RNA - cerebellum [nTPM]":"75.4","Tissue RNA - cerebral cortex [nTPM]":"92.5","Tissue RNA - cervix [nTPM]":"123.8","Tissue RNA - choroid plexus [nTPM]":"78.3","Tissue RNA - colon [nTPM]":"121.0","Tissue RNA - duodenum [nTPM]":"61.2","Tissue RNA - endometrium 1 [nTPM]":"95.5","Tissue RNA - epididymis [nTPM]":"29.6","Tissue RNA - esophagus [nTPM]":"151.8","Tissue RNA - fallopian tube [nTPM]":"141.2","Tissue RNA - gallbladder [nTPM]":"130.4","Tissue RNA - heart muscle [nTPM]":"145.5","Tissue RNA - hippocampal formation [nTPM]":"71.4","Tissue RNA - hypothalamus [nTPM]":"75.9","Tissue RNA - kidney [nTPM]":"104.5","Tissue RNA - liver [nTPM]":"208.1","Tissue RNA - lung [nTPM]":"366.0","Tissue RNA - lymph node [nTPM]":"122.6","Tissue RNA - medulla oblongata [nTPM]":"90.1","Tissue RNA - midbrain [nTPM]":"76.2","Tissue RNA - ovary [nTPM]":"255.7","Tissue RNA - pancreas [nTPM]":"101.9","Tissue RNA - parathyroid gland [nTPM]":"68.8","Tissue RNA - pituitary gland [nTPM]":"92.4","Tissue RNA - placenta [nTPM]":"92.7","Tissue RNA - pons [nTPM]":"81.6","Tissue RNA - prostate [nTPM]":"112.6","Tissue RNA - rectum [nTPM]":"80.9","Tissue RNA - retina [nTPM]":"18.7","Tissue RNA - salivary gland [nTPM]":"118.3","Tissue RNA - seminal vesicle [nTPM]":"110.0","Tissue RNA - skeletal muscle [nTPM]":"139.7","Tissue RNA - skin 1 [nTPM]":"260.5","Tissue RNA - small intestine [nTPM]":"148.5","Tissue RNA - smooth muscle [nTPM]":"92.7","Tissue RNA - spinal cord [nTPM]":"77.0","Tissue RNA - spleen [nTPM]":"226.2","Tissue RNA - stomach 1 [nTPM]":"130.7","Tissue RNA - testis [nTPM]":"31.7","Tissue RNA - thalamus [nTPM]":"84.9","Tissue RNA - thymus [nTPM]":"123.2","Tissue RNA - thyroid gland [nTPM]":"111.9","Tissue RNA - tongue [nTPM]":"138.3","Tissue RNA - tonsil [nTPM]":"181.4","Tissue RNA - urinary bladder [nTPM]":"366.2","Tissue RNA - vagina [nTPM]":"166.8","Tissue RNA - white matter [nTPM]":"79.8","Cell RNA - A-431 [nTPM]":"62.5","Cell RNA - A549 [nTPM]":"54.1","Cell RNA - AF22 [nTPM]":"20.1","Cell RNA - AN3-CA [nTPM]":"18.2","Cell RNA - ASC diff [nTPM]":"114.7","Cell RNA - ASC TERT1 [nTPM]":"75.9","Cell RNA - BEWO [nTPM]":"71.1","Cell RNA - BJ [nTPM]":"25.2","Cell RNA - BJ hTERT+ [nTPM]":"240.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"53.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"47.3","Cell RNA - CACO-2 [nTPM]":"16.9","Cell RNA - CAPAN-2 [nTPM]":"36.5","Cell RNA - Daudi [nTPM]":"37.5","Cell RNA - EFO-21 [nTPM]":"66.1","Cell RNA - fHDF\/TERT166 [nTPM]":"40.2","Cell RNA - GAMG [nTPM]":"125.2","Cell RNA - HaCaT [nTPM]":"79.5","Cell RNA - HAP1 [nTPM]":"38.3","Cell RNA - HBEC3-KT [nTPM]":"104.9","Cell RNA - HBF TERT88 [nTPM]":"76.1","Cell RNA - HDLM-2 [nTPM]":"229.2","Cell RNA - HEK 293 [nTPM]":"14.9","Cell RNA - HEL [nTPM]":"18.6","Cell RNA - HeLa [nTPM]":"39.9","Cell RNA - Hep G2 [nTPM]":"101.4","Cell RNA - HHSteC [nTPM]":"68.6","Cell RNA - HL-60 [nTPM]":"29.9","Cell RNA - HMC-1 [nTPM]":"15.0","Cell RNA - HSkMC [nTPM]":"83.1","Cell RNA - hTCEpi [nTPM]":"103.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"36.4","Cell RNA - hTERT-HME1 [nTPM]":"92.2","Cell RNA - hTERT-RPE1 [nTPM]":"35.5","Cell RNA - HUVEC TERT2 [nTPM]":"48.6","Cell RNA - JURKAT [nTPM]":"18.4","Cell RNA - K-562 [nTPM]":"15.9","Cell RNA - Karpas-707 [nTPM]":"58.4","Cell RNA - LHCN-M2 [nTPM]":"38.6","Cell RNA - MCF7 [nTPM]":"73.0","Cell RNA - MOLT-4 [nTPM]":"39.2","Cell RNA - NB-4 [nTPM]":"71.0","Cell RNA - NTERA-2 [nTPM]":"18.6","Cell RNA - OE19 [nTPM]":"60.0","Cell RNA - PC-3 [nTPM]":"33.1","Cell RNA - REH [nTPM]":"87.8","Cell RNA - RH-30 [nTPM]":"23.1","Cell RNA - RPMI-8226 [nTPM]":"31.6","Cell RNA - RPTEC TERT1 [nTPM]":"92.8","Cell RNA - RT4 [nTPM]":"391.7","Cell RNA - SCLC-21H [nTPM]":"17.9","Cell RNA - SH-SY5Y [nTPM]":"31.2","Cell RNA - SiHa [nTPM]":"67.2","Cell RNA - SK-BR-3 [nTPM]":"115.9","Cell RNA - SK-MEL-30 [nTPM]":"29.7","Cell RNA - SuSa [nTPM]":"41.0","Cell RNA - T-47d [nTPM]":"66.1","Cell RNA - THP-1 [nTPM]":"62.2","Cell RNA - TIME [nTPM]":"91.7","Cell RNA - U-138 MG [nTPM]":"72.8","Cell RNA - U-2 OS [nTPM]":"26.5","Cell RNA - U-2197 [nTPM]":"21.3","Cell RNA - U-251 MG [nTPM]":"41.0","Cell RNA - U-266\/70 [nTPM]":"70.9","Cell RNA - U-266\/84 [nTPM]":"77.7","Cell RNA - U-698 [nTPM]":"64.5","Cell RNA - U-87 MG [nTPM]":"60.8","Cell RNA - U-937 [nTPM]":"22.0","Cell RNA - WM-115 [nTPM]":"15.3","Blood RNA - basophil [nTPM]":"322.0","Blood RNA - classical monocyte [nTPM]":"444.9","Blood RNA - eosinophil [nTPM]":"301.4","Blood RNA - gdT-cell [nTPM]":"175.3","Blood RNA - intermediate monocyte [nTPM]":"267.2","Blood RNA - MAIT T-cell [nTPM]":"264.0","Blood RNA - memory B-cell [nTPM]":"258.4","Blood RNA - memory CD4 T-cell [nTPM]":"207.1","Blood RNA - memory CD8 T-cell [nTPM]":"182.5","Blood RNA - myeloid DC [nTPM]":"428.9","Blood RNA - naive B-cell [nTPM]":"329.7","Blood RNA - naive CD4 T-cell [nTPM]":"178.1","Blood RNA - naive CD8 T-cell [nTPM]":"153.0","Blood RNA - neutrophil [nTPM]":"942.9","Blood RNA - NK-cell [nTPM]":"285.9","Blood RNA - non-classical monocyte [nTPM]":"183.7","Blood RNA - plasmacytoid DC [nTPM]":"233.0","Blood RNA - T-reg [nTPM]":"154.9","Blood RNA - total PBMC [nTPM]":"506.4","Brain RNA - amygdala [nTPM]":"75.6","Brain RNA - basal ganglia [nTPM]":"78.0","Brain RNA - cerebellum [nTPM]":"75.4","Brain RNA - cerebral cortex [nTPM]":"92.5","Brain RNA - hippocampal formation [nTPM]":"71.4","Brain RNA - hypothalamus [nTPM]":"75.9","Brain RNA - medulla oblongata [nTPM]":"90.1","Brain RNA - midbrain [nTPM]":"76.2","Brain RNA - pons [nTPM]":"81.6","Brain RNA - spinal cord [nTPM]":"77.0","Brain RNA - thalamus [nTPM]":"84.9","Brain RNA - white matter [nTPM]":"79.8","Single Cell Type RNA - Adipocytes [nTPM]":"802.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"535.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"914.0","Single Cell Type RNA - Astrocytes [nTPM]":"14.4","Single Cell Type RNA - B-cells [nTPM]":"505.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4056.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1862.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2061.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1729.6","Single Cell Type RNA - Bipolar cells [nTPM]":"27.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"430.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"414.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"188.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"367.4","Single Cell Type RNA - Club cells [nTPM]":"719.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"62.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"12.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"196.4","Single Cell Type RNA - dendritic cells [nTPM]":"762.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"447.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"195.6","Single Cell Type RNA - Ductal cells [nTPM]":"875.0","Single Cell Type RNA - Early spermatids [nTPM]":"4.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"703.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"935.6","Single Cell Type RNA - Endothelial cells [nTPM]":"1079.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"203.5","Single Cell Type RNA - Erythroid cells [nTPM]":"87.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"394.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"174.9","Single Cell Type RNA - Fibroblasts [nTPM]":"1145.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"333.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1440.1","Single Cell Type RNA - granulocytes [nTPM]":"906.1","Single Cell Type RNA - Granulosa cells [nTPM]":"68.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"313.4","Single Cell Type RNA - Hepatocytes [nTPM]":"147.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"791.2","Single Cell Type RNA - Horizontal cells [nTPM]":"48.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"453.0","Single Cell Type RNA - Ionocytes [nTPM]":"634.7","Single Cell Type RNA - Kupffer cells [nTPM]":"491.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4828.7","Single Cell Type RNA - Late spermatids [nTPM]":"14.7","Single Cell Type RNA - Leydig cells [nTPM]":"153.1","Single Cell Type RNA - Macrophages [nTPM]":"1609.0","Single Cell Type RNA - Melanocytes [nTPM]":"1085.1","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"428.1","Single Cell Type RNA - Muller glia cells [nTPM]":"95.2","Single Cell Type RNA - NK-cells [nTPM]":"97.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"383.5","Single Cell Type RNA - Paneth cells [nTPM]":"511.5","Single Cell Type RNA - Peritubular cells [nTPM]":"116.2","Single Cell Type RNA - Plasma cells [nTPM]":"1039.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1412.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1051.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"115.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"298.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.4","Single Cell Type RNA - Sertoli cells [nTPM]":"203.8","Single Cell Type RNA - Skeletal myocytes [nTPM]":"956.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"847.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.3","Single Cell Type RNA - Spermatogonia [nTPM]":"26.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1544.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"3420.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"660.0","Single Cell Type RNA - T-cells [nTPM]":"838.4","Single Cell Type RNA - Theca cells [nTPM]":"91.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"346.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1004.6"},{"Gene":"NFKBIE","Gene synonym":["IKBE"],"Ensembl":"ENSG00000146232","Gene description":"NFKB inhibitor epsilon","Uniprot":["O00221"],"Chromosome":"6","Position":"44258166-44265788","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"151.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002692","HPA005941","CAB010272"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 2: Immune cells - Immune response","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB010272":"AB_2235977","HPA002692":"AB_1079479","HPA005941":"AB_1079478"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.72e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.32e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.50e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.88e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.60e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.37e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.61e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.83e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.37e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.07e-4"},"Tissue RNA - adipose tissue [nTPM]":"6.8","Tissue RNA - adrenal gland [nTPM]":"5.8","Tissue RNA - amygdala [nTPM]":"10.9","Tissue RNA - appendix [nTPM]":"19.1","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"31.5","Tissue RNA - breast [nTPM]":"5.9","Tissue RNA - cerebellum [nTPM]":"12.1","Tissue RNA - cerebral cortex [nTPM]":"17.6","Tissue RNA - cervix [nTPM]":"4.1","Tissue RNA - choroid plexus [nTPM]":"10.7","Tissue RNA - colon [nTPM]":"7.2","Tissue RNA - duodenum [nTPM]":"7.4","Tissue RNA - endometrium 1 [nTPM]":"3.7","Tissue RNA - epididymis [nTPM]":"4.7","Tissue RNA - esophagus [nTPM]":"5.9","Tissue RNA - fallopian tube [nTPM]":"3.3","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"5.3","Tissue RNA - hippocampal formation [nTPM]":"11.3","Tissue RNA - hypothalamus [nTPM]":"10.6","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"10.5","Tissue RNA - lung [nTPM]":"13.6","Tissue RNA - lymph node [nTPM]":"19.9","Tissue RNA - medulla oblongata [nTPM]":"11.5","Tissue RNA - midbrain [nTPM]":"11.4","Tissue RNA - ovary [nTPM]":"2.7","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"5.3","Tissue RNA - pituitary gland [nTPM]":"4.5","Tissue RNA - placenta [nTPM]":"5.5","Tissue RNA - pons [nTPM]":"11.2","Tissue RNA - prostate [nTPM]":"8.3","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"3.7","Tissue RNA - salivary gland [nTPM]":"7.4","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"3.5","Tissue RNA - skin 1 [nTPM]":"9.9","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"3.6","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"35.0","Tissue RNA - stomach 1 [nTPM]":"7.0","Tissue RNA - testis [nTPM]":"10.7","Tissue RNA - thalamus [nTPM]":"11.8","Tissue RNA - thymus [nTPM]":"9.9","Tissue RNA - thyroid gland [nTPM]":"5.3","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"25.1","Tissue RNA - urinary bladder [nTPM]":"16.3","Tissue RNA - vagina [nTPM]":"5.0","Tissue RNA - white matter [nTPM]":"12.3","Cell RNA - A-431 [nTPM]":"28.4","Cell RNA - A549 [nTPM]":"7.9","Cell RNA - AF22 [nTPM]":"9.5","Cell RNA - AN3-CA [nTPM]":"15.1","Cell RNA - ASC diff [nTPM]":"3.7","Cell RNA - ASC TERT1 [nTPM]":"2.8","Cell RNA - BEWO [nTPM]":"5.3","Cell RNA - BJ [nTPM]":"4.9","Cell RNA - BJ hTERT+ [nTPM]":"23.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"15.4","Cell RNA - CACO-2 [nTPM]":"15.0","Cell RNA - CAPAN-2 [nTPM]":"12.9","Cell RNA - Daudi [nTPM]":"15.7","Cell RNA - EFO-21 [nTPM]":"17.0","Cell RNA - fHDF\/TERT166 [nTPM]":"5.1","Cell RNA - GAMG [nTPM]":"39.7","Cell RNA - HaCaT [nTPM]":"6.2","Cell RNA - HAP1 [nTPM]":"10.3","Cell RNA - HBEC3-KT [nTPM]":"15.4","Cell RNA - HBF TERT88 [nTPM]":"16.6","Cell RNA - HDLM-2 [nTPM]":"26.1","Cell RNA - HEK 293 [nTPM]":"6.0","Cell RNA - HEL [nTPM]":"7.9","Cell RNA - HeLa [nTPM]":"3.0","Cell RNA - Hep G2 [nTPM]":"17.0","Cell RNA - HHSteC [nTPM]":"11.4","Cell RNA - HL-60 [nTPM]":"26.1","Cell RNA - HMC-1 [nTPM]":"23.0","Cell RNA - HSkMC [nTPM]":"7.1","Cell RNA - hTCEpi [nTPM]":"6.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.8","Cell RNA - hTERT-HME1 [nTPM]":"8.8","Cell RNA - hTERT-RPE1 [nTPM]":"12.5","Cell RNA - HUVEC TERT2 [nTPM]":"10.7","Cell RNA - JURKAT [nTPM]":"7.2","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"39.2","Cell RNA - LHCN-M2 [nTPM]":"3.9","Cell RNA - MCF7 [nTPM]":"14.4","Cell RNA - MOLT-4 [nTPM]":"5.2","Cell RNA - NB-4 [nTPM]":"52.7","Cell RNA - NTERA-2 [nTPM]":"5.0","Cell RNA - OE19 [nTPM]":"44.1","Cell RNA - PC-3 [nTPM]":"4.0","Cell RNA - REH [nTPM]":"9.9","Cell RNA - RH-30 [nTPM]":"8.5","Cell RNA - RPMI-8226 [nTPM]":"14.0","Cell RNA - RPTEC TERT1 [nTPM]":"34.7","Cell RNA - RT4 [nTPM]":"30.3","Cell RNA - SCLC-21H [nTPM]":"6.1","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"3.4","Cell RNA - SK-BR-3 [nTPM]":"12.5","Cell RNA - SK-MEL-30 [nTPM]":"20.9","Cell RNA - SuSa [nTPM]":"8.0","Cell RNA - T-47d [nTPM]":"8.6","Cell RNA - THP-1 [nTPM]":"29.9","Cell RNA - TIME [nTPM]":"18.1","Cell RNA - U-138 MG [nTPM]":"8.4","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"5.3","Cell RNA - U-251 MG [nTPM]":"15.4","Cell RNA - U-266\/70 [nTPM]":"25.0","Cell RNA - U-266\/84 [nTPM]":"11.4","Cell RNA - U-698 [nTPM]":"28.7","Cell RNA - U-87 MG [nTPM]":"7.4","Cell RNA - U-937 [nTPM]":"28.4","Cell RNA - WM-115 [nTPM]":"16.1","Blood RNA - basophil [nTPM]":"8.8","Blood RNA - classical monocyte [nTPM]":"7.5","Blood RNA - eosinophil [nTPM]":"4.0","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"9.4","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"8.6","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"6.6","Blood RNA - naive B-cell [nTPM]":"6.5","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"1.6","Blood RNA - neutrophil [nTPM]":"3.0","Blood RNA - NK-cell [nTPM]":"0.8","Blood RNA - non-classical monocyte [nTPM]":"11.1","Blood RNA - plasmacytoid DC [nTPM]":"8.1","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"10.9","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"12.1","Brain RNA - cerebral cortex [nTPM]":"17.6","Brain RNA - hippocampal formation [nTPM]":"11.3","Brain RNA - hypothalamus [nTPM]":"10.6","Brain RNA - medulla oblongata [nTPM]":"11.5","Brain RNA - midbrain [nTPM]":"11.4","Brain RNA - pons [nTPM]":"11.2","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.8","Brain RNA - white matter [nTPM]":"12.3","Single Cell Type RNA - Adipocytes [nTPM]":"7.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.7","Single Cell Type RNA - Astrocytes [nTPM]":"1.0","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"28.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"14.8","Single Cell Type RNA - Bipolar cells [nTPM]":"3.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"9.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"5.2","Single Cell Type RNA - dendritic cells [nTPM]":"12.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"49.5","Single Cell Type RNA - Early spermatids [nTPM]":"17.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"15.9","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.9","Single Cell Type RNA - Erythroid cells [nTPM]":"1.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"21.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.0","Single Cell Type RNA - Fibroblasts [nTPM]":"17.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"10.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"12.8","Single Cell Type RNA - granulocytes [nTPM]":"32.5","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.2","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.9","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"22.6","Single Cell Type RNA - Langerhans cells [nTPM]":"151.2","Single Cell Type RNA - Late spermatids [nTPM]":"34.1","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"48.6","Single Cell Type RNA - Melanocytes [nTPM]":"48.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"55.2","Single Cell Type RNA - Muller glia cells [nTPM]":"3.3","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"58.9","Single Cell Type RNA - Paneth cells [nTPM]":"33.3","Single Cell Type RNA - Peritubular cells [nTPM]":"2.6","Single Cell Type RNA - Plasma cells [nTPM]":"18.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"32.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"14.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.0","Single Cell Type RNA - Spermatocytes [nTPM]":"25.9","Single Cell Type RNA - Spermatogonia [nTPM]":"12.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"11.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"39.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.3","Single Cell Type RNA - T-cells [nTPM]":"13.8","Single Cell Type RNA - Theca cells [nTPM]":"7.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.5","Single Cell Type RNA - Urothelial cells [nTPM]":"34.7"},{"Gene":"NKX3-1","Gene synonym":["BAPX2","NKX3.1","NKX3A"],"Ensembl":"ENSG00000167034","Gene description":"NK3 homeobox 1","Uniprot":["Q99801"],"Chromosome":"8","Position":"23678697-23682938","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"prostate":"303.3"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Basal prostatic cells":"51.0","Prostatic glandular cells":"124.8"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"65","RNA cancer specific FPKM":{"prostate cancer":"392.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"eosinophil":"54.0","neutrophil":"51.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"21","RNA blood lineage specific nTPM":{"granulocytes":"54.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"25.7","SiHa":"26.1","U-138 MG":"25.8","U-251 MG":"23.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA025693","HPA078571"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 51: Non-specific - Unknown function","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA025693":"AB_1854522","HPA078571":"AB_2732384"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.47e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.03e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-6"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.90e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.11e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.60e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"1.7","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.5","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"2.2","Tissue RNA - breast [nTPM]":"2.1","Tissue RNA - cerebellum [nTPM]":"1.4","Tissue RNA - cerebral cortex [nTPM]":"1.4","Tissue RNA - cervix [nTPM]":"1.1","Tissue RNA - choroid plexus [nTPM]":"0.9","Tissue RNA - colon [nTPM]":"1.4","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"1.5","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"3.7","Tissue RNA - fallopian tube [nTPM]":"1.8","Tissue RNA - gallbladder [nTPM]":"1.1","Tissue RNA - heart muscle [nTPM]":"2.6","Tissue RNA - hippocampal formation [nTPM]":"1.2","Tissue RNA - hypothalamus [nTPM]":"1.6","Tissue RNA - kidney [nTPM]":"1.4","Tissue RNA - liver [nTPM]":"4.1","Tissue RNA - lung [nTPM]":"1.4","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"1.8","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"1.8","Tissue RNA - parathyroid gland [nTPM]":"1.0","Tissue RNA - pituitary gland [nTPM]":"0.9","Tissue RNA - placenta [nTPM]":"0.8","Tissue RNA - pons [nTPM]":"1.6","Tissue RNA - prostate [nTPM]":"303.3","Tissue RNA - rectum [nTPM]":"0.5","Tissue RNA - retina [nTPM]":"1.7","Tissue RNA - salivary gland [nTPM]":"62.0","Tissue RNA - seminal vesicle [nTPM]":"1.8","Tissue RNA - skeletal muscle [nTPM]":"3.2","Tissue RNA - skin 1 [nTPM]":"0.4","Tissue RNA - small intestine [nTPM]":"1.0","Tissue RNA - smooth muscle [nTPM]":"1.9","Tissue RNA - spinal cord [nTPM]":"1.7","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"24.0","Tissue RNA - thalamus [nTPM]":"1.5","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"0.7","Tissue RNA - tongue [nTPM]":"3.9","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"2.9","Tissue RNA - vagina [nTPM]":"1.9","Tissue RNA - white matter [nTPM]":"1.4","Cell RNA - A-431 [nTPM]":"4.9","Cell RNA - A549 [nTPM]":"3.7","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"8.7","Cell RNA - ASC diff [nTPM]":"3.1","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"7.1","Cell RNA - BJ [nTPM]":"6.7","Cell RNA - BJ hTERT+ [nTPM]":"4.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"13.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.2","Cell RNA - CACO-2 [nTPM]":"2.1","Cell RNA - CAPAN-2 [nTPM]":"5.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"5.0","Cell RNA - GAMG [nTPM]":"25.7","Cell RNA - HaCaT [nTPM]":"1.2","Cell RNA - HAP1 [nTPM]":"3.5","Cell RNA - HBEC3-KT [nTPM]":"7.6","Cell RNA - HBF TERT88 [nTPM]":"10.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.8","Cell RNA - HEL [nTPM]":"3.4","Cell RNA - HeLa [nTPM]":"2.6","Cell RNA - Hep G2 [nTPM]":"5.5","Cell RNA - HHSteC [nTPM]":"6.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"1.2","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"14.0","Cell RNA - hTERT-HME1 [nTPM]":"0.8","Cell RNA - hTERT-RPE1 [nTPM]":"8.5","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"20.1","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"5.5","Cell RNA - MCF7 [nTPM]":"1.6","Cell RNA - MOLT-4 [nTPM]":"11.8","Cell RNA - NB-4 [nTPM]":"1.0","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"2.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"5.5","Cell RNA - RPMI-8226 [nTPM]":"0.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.8","Cell RNA - RT4 [nTPM]":"5.7","Cell RNA - SCLC-21H [nTPM]":"1.6","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"26.1","Cell RNA - SK-BR-3 [nTPM]":"4.8","Cell RNA - SK-MEL-30 [nTPM]":"0.4","Cell RNA - SuSa [nTPM]":"9.9","Cell RNA - T-47d [nTPM]":"3.5","Cell RNA - THP-1 [nTPM]":"0.5","Cell RNA - TIME [nTPM]":"0.9","Cell RNA - U-138 MG [nTPM]":"25.8","Cell RNA - U-2 OS [nTPM]":"9.1","Cell RNA - U-2197 [nTPM]":"2.0","Cell RNA - U-251 MG [nTPM]":"23.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"12.5","Cell RNA - U-937 [nTPM]":"2.6","Cell RNA - WM-115 [nTPM]":"3.2","Blood RNA - basophil [nTPM]":"10.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"54.0","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.2","Blood RNA - memory B-cell [nTPM]":"2.2","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.4","Blood RNA - naive CD8 T-cell [nTPM]":"2.5","Blood RNA - neutrophil [nTPM]":"51.6","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.4","Brain RNA - cerebral cortex [nTPM]":"1.4","Brain RNA - hippocampal formation [nTPM]":"1.2","Brain RNA - hypothalamus [nTPM]":"1.6","Brain RNA - medulla oblongata [nTPM]":"1.8","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"1.6","Brain RNA - spinal cord [nTPM]":"1.7","Brain RNA - thalamus [nTPM]":"1.5","Brain RNA - white matter [nTPM]":"1.4","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"51.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"4.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"3.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"2.0","Single Cell Type RNA - Endothelial cells [nTPM]":"6.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.6","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"9.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"4.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"9.4","Single Cell Type RNA - Late spermatids [nTPM]":"6.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"2.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"5.2","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"1.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"124.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"5.1","Single Cell Type RNA - Spermatocytes [nTPM]":"1.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"2.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.1","Single Cell Type RNA - Urothelial cells [nTPM]":"12.2"},{"Gene":"NOS2","Gene synonym":["HEP-NOS","iNOS","NOS","NOS2A"],"Ensembl":"ENSG00000007171","Gene description":"Nitric oxide synthase 2","Uniprot":["P35228"],"Chromosome":"17","Position":"27756766-27800529","Protein class":["Cancer-related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Calmodulin-binding","Oxidoreductase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"21.1","lymphoid tissue":"14.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"40.3","Extravillous trophoblasts":"27.7","Granulosa cells":"57.3","Proximal enterocytes":"10.7","Undifferentiated cells":"10.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"colorectal cancer":"16.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in some","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"CACO-2":"16.5","SCLC-21H":"13.0"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002014"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 56: Intestine - Transmembrane transport","Cell line expression cluster":"Cluster 39: CACO-2 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002014":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.08e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.42e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.13e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.09e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.91e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.04e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.02e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.69e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.9","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"0.2","Tissue RNA - appendix [nTPM]":"14.4","Tissue RNA - basal ganglia [nTPM]":"0.5","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.3","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"2.1","Tissue RNA - cervix [nTPM]":"0.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"12.1","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.7","Tissue RNA - fallopian tube [nTPM]":"0.4","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"0.4","Tissue RNA - hippocampal formation [nTPM]":"0.7","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"1.6","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"1.8","Tissue RNA - lymph node [nTPM]":"0.8","Tissue RNA - medulla oblongata [nTPM]":"0.3","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"0.6","Tissue RNA - pancreas [nTPM]":"0.3","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"1.3","Tissue RNA - placenta [nTPM]":"0.6","Tissue RNA - pons [nTPM]":"0.5","Tissue RNA - prostate [nTPM]":"0.6","Tissue RNA - rectum [nTPM]":"8.9","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"0.1","Tissue RNA - seminal vesicle [nTPM]":"0.2","Tissue RNA - skeletal muscle [nTPM]":"0.8","Tissue RNA - skin 1 [nTPM]":"0.2","Tissue RNA - small intestine [nTPM]":"21.1","Tissue RNA - smooth muscle [nTPM]":"1.8","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.1","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"1.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.4","Tissue RNA - tongue [nTPM]":"0.7","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"3.6","Tissue RNA - vagina [nTPM]":"0.2","Tissue RNA - white matter [nTPM]":"0.9","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"16.5","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"1.7","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"13.0","Cell RNA - SH-SY5Y [nTPM]":"0.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.2","Brain RNA - basal ganglia [nTPM]":"0.5","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"2.1","Brain RNA - hippocampal formation [nTPM]":"0.7","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.3","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.5","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"1.0","Brain RNA - white matter [nTPM]":"0.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"1.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"40.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"27.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"57.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"2.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"4.9","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"1.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.3","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"NOTCH1","Gene synonym":["TAN1"],"Ensembl":"ENSG00000148400","Gene description":"Notch receptor 1","Uniprot":["P46531"],"Chromosome":"9","Position":"136494433-136546048","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Angiogenesis","Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"56.2","Astrocytes":"67.3","Hepatic stellate cells":"68.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HaCaT":"47.0","HDLM-2":"32.3","HMC-1":"39.7","MOLT-4":"72.3"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB008112","CAB022466","HPA067168"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"29000000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB008112":"AB_2153490","CAB022466":null,"HPA067168":"AB_2685795"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.38e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.74e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.78e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.50e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.45e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"18.2","Tissue RNA - adrenal gland [nTPM]":"4.2","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"4.9","Tissue RNA - basal ganglia [nTPM]":"16.1","Tissue RNA - bone marrow [nTPM]":"4.3","Tissue RNA - breast [nTPM]":"15.0","Tissue RNA - cerebellum [nTPM]":"12.1","Tissue RNA - cerebral cortex [nTPM]":"9.3","Tissue RNA - cervix [nTPM]":"14.3","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"19.8","Tissue RNA - duodenum [nTPM]":"4.3","Tissue RNA - endometrium 1 [nTPM]":"12.7","Tissue RNA - epididymis [nTPM]":"0.2","Tissue RNA - esophagus [nTPM]":"16.3","Tissue RNA - fallopian tube [nTPM]":"11.9","Tissue RNA - gallbladder [nTPM]":"0.9","Tissue RNA - heart muscle [nTPM]":"14.9","Tissue RNA - hippocampal formation [nTPM]":"8.6","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"11.8","Tissue RNA - liver [nTPM]":"9.2","Tissue RNA - lung [nTPM]":"22.2","Tissue RNA - lymph node [nTPM]":"3.0","Tissue RNA - medulla oblongata [nTPM]":"13.5","Tissue RNA - midbrain [nTPM]":"12.3","Tissue RNA - ovary [nTPM]":"5.1","Tissue RNA - pancreas [nTPM]":"14.0","Tissue RNA - parathyroid gland [nTPM]":"0.7","Tissue RNA - pituitary gland [nTPM]":"6.3","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"9.8","Tissue RNA - prostate [nTPM]":"15.4","Tissue RNA - rectum [nTPM]":"0.6","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"10.7","Tissue RNA - seminal vesicle [nTPM]":"3.1","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"14.2","Tissue RNA - smooth muscle [nTPM]":"1.3","Tissue RNA - spinal cord [nTPM]":"9.7","Tissue RNA - spleen [nTPM]":"24.8","Tissue RNA - stomach 1 [nTPM]":"10.0","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"13.9","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"1.2","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"14.2","Tissue RNA - vagina [nTPM]":"16.5","Tissue RNA - white matter [nTPM]":"14.0","Cell RNA - A-431 [nTPM]":"8.8","Cell RNA - A549 [nTPM]":"10.6","Cell RNA - AF22 [nTPM]":"4.0","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"17.7","Cell RNA - BJ [nTPM]":"3.3","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.4","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"0.9","Cell RNA - Daudi [nTPM]":"13.3","Cell RNA - EFO-21 [nTPM]":"10.3","Cell RNA - fHDF\/TERT166 [nTPM]":"1.3","Cell RNA - GAMG [nTPM]":"1.6","Cell RNA - HaCaT [nTPM]":"47.0","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"8.6","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"32.3","Cell RNA - HEK 293 [nTPM]":"2.0","Cell RNA - HEL [nTPM]":"5.5","Cell RNA - HeLa [nTPM]":"6.1","Cell RNA - Hep G2 [nTPM]":"0.6","Cell RNA - HHSteC [nTPM]":"2.1","Cell RNA - HL-60 [nTPM]":"6.9","Cell RNA - HMC-1 [nTPM]":"39.7","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"16.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1.4","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"9.0","Cell RNA - JURKAT [nTPM]":"3.7","Cell RNA - K-562 [nTPM]":"3.6","Cell RNA - Karpas-707 [nTPM]":"1.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"72.3","Cell RNA - NB-4 [nTPM]":"13.1","Cell RNA - NTERA-2 [nTPM]":"8.4","Cell RNA - OE19 [nTPM]":"2.9","Cell RNA - PC-3 [nTPM]":"7.7","Cell RNA - REH [nTPM]":"15.7","Cell RNA - RH-30 [nTPM]":"9.2","Cell RNA - RPMI-8226 [nTPM]":"19.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.6","Cell RNA - RT4 [nTPM]":"4.2","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.7","Cell RNA - SiHa [nTPM]":"6.1","Cell RNA - SK-BR-3 [nTPM]":"4.3","Cell RNA - SK-MEL-30 [nTPM]":"3.4","Cell RNA - SuSa [nTPM]":"1.0","Cell RNA - T-47d [nTPM]":"3.2","Cell RNA - THP-1 [nTPM]":"10.4","Cell RNA - TIME [nTPM]":"22.7","Cell RNA - U-138 MG [nTPM]":"5.0","Cell RNA - U-2 OS [nTPM]":"9.3","Cell RNA - U-2197 [nTPM]":"5.9","Cell RNA - U-251 MG [nTPM]":"4.3","Cell RNA - U-266\/70 [nTPM]":"2.4","Cell RNA - U-266\/84 [nTPM]":"2.6","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"3.7","Cell RNA - U-937 [nTPM]":"5.0","Cell RNA - WM-115 [nTPM]":"26.1","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.4","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"0.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"0.3","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"2.3","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.1","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"16.1","Brain RNA - cerebellum [nTPM]":"12.1","Brain RNA - cerebral cortex [nTPM]":"9.3","Brain RNA - hippocampal formation [nTPM]":"8.6","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"13.5","Brain RNA - midbrain [nTPM]":"12.3","Brain RNA - pons [nTPM]":"9.8","Brain RNA - spinal cord [nTPM]":"9.7","Brain RNA - thalamus [nTPM]":"13.9","Brain RNA - white matter [nTPM]":"14.0","Single Cell Type RNA - Adipocytes [nTPM]":"56.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"21.9","Single Cell Type RNA - Astrocytes [nTPM]":"67.3","Single Cell Type RNA - B-cells [nTPM]":"8.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"35.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"16.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - dendritic cells [nTPM]":"14.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"11.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"5.1","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"53.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"6.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.3","Single Cell Type RNA - granulocytes [nTPM]":"34.9","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.2","Single Cell Type RNA - Hepatocytes [nTPM]":"7.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.3","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.8","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"10.1","Single Cell Type RNA - Langerhans cells [nTPM]":"17.5","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"1.2","Single Cell Type RNA - Macrophages [nTPM]":"15.2","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"18.7","Single Cell Type RNA - monocytes [nTPM]":"14.3","Single Cell Type RNA - Muller glia cells [nTPM]":"46.6","Single Cell Type RNA - NK-cells [nTPM]":"24.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"33.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"19.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.1","Single Cell Type RNA - Paneth cells [nTPM]":"11.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.7","Single Cell Type RNA - Plasma cells [nTPM]":"5.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"4.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"14.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"3.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"29.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.1","Single Cell Type RNA - T-cells [nTPM]":"15.0","Single Cell Type RNA - Theca cells [nTPM]":"1.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.8","Single Cell Type RNA - Urothelial cells [nTPM]":"15.6"},{"Gene":"NOTCH4","Gene synonym":["INT3"],"Ensembl":"ENSG00000204301","Gene description":"Notch receptor 4","Uniprot":["Q99466"],"Chromosome":"6","Position":"32194843-32224067","Protein class":["Human disease related genes","Predicted membrane proteins"],"Biological process":["Differentiation","Notch signaling pathway","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"24.2","breast":"19.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Adipocytes":"263.8","Endothelial cells":"121.0","Hepatic stellate cells":"188.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6400000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.80e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.88e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.84e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.2","Tissue RNA - adrenal gland [nTPM]":"4.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"19.8","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"5.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.6","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"2.7","Tissue RNA - fallopian tube [nTPM]":"5.8","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"8.5","Tissue RNA - liver [nTPM]":"2.5","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"0.4","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"2.8","Tissue RNA - pancreas [nTPM]":"2.6","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"3.0","Tissue RNA - placenta [nTPM]":"1.4","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"6.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"2.6","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"5.6","Tissue RNA - skin 1 [nTPM]":"2.8","Tissue RNA - small intestine [nTPM]":"3.9","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"2.6","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"9.6","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.1","Tissue RNA - urinary bladder [nTPM]":"5.0","Tissue RNA - vagina [nTPM]":"4.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"263.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"6.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"5.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"13.6","Single Cell Type RNA - Bipolar cells [nTPM]":"2.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.4","Single Cell Type RNA - dendritic cells [nTPM]":"11.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"2.6","Single Cell Type RNA - Early spermatids [nTPM]":"46.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"3.1","Single Cell Type RNA - Endothelial cells [nTPM]":"121.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"12.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"4.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"188.8","Single Cell Type RNA - Hepatocytes [nTPM]":"2.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.7","Single Cell Type RNA - Horizontal cells [nTPM]":"6.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.8","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"9.3","Single Cell Type RNA - Langerhans cells [nTPM]":"5.2","Single Cell Type RNA - Late spermatids [nTPM]":"35.6","Single Cell Type RNA - Leydig cells [nTPM]":"7.2","Single Cell Type RNA - Macrophages [nTPM]":"6.8","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"10.3","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"21.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.3","Single Cell Type RNA - Peritubular cells [nTPM]":"5.3","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"1.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"3.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.3","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"3.6","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.9","Single Cell Type RNA - Urothelial cells [nTPM]":"5.6"},{"Gene":"NPM1","Gene synonym":["B23","NPM"],"Ensembl":"ENSG00000181163","Gene description":"Nucleophosmin 1","Uniprot":["P06748"],"Chromosome":"5","Position":"171387116-171411810","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction"],"Molecular function":["Chaperone","RNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA011384","CAB012983"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2000000","Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoli rim"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB012983":"AB_2533084","HPA011384":"AB_1854692"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.59e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.48e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.82e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.25e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.39e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.89e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-2"},"Tissue RNA - adipose tissue [nTPM]":"515.1","Tissue RNA - adrenal gland [nTPM]":"370.6","Tissue RNA - amygdala [nTPM]":"180.7","Tissue RNA - appendix [nTPM]":"468.4","Tissue RNA - basal ganglia [nTPM]":"190.3","Tissue RNA - bone marrow [nTPM]":"789.2","Tissue RNA - breast [nTPM]":"597.1","Tissue RNA - cerebellum [nTPM]":"188.6","Tissue RNA - cerebral cortex [nTPM]":"233.5","Tissue RNA - cervix [nTPM]":"759.2","Tissue RNA - choroid plexus [nTPM]":"195.9","Tissue RNA - colon [nTPM]":"486.6","Tissue RNA - duodenum [nTPM]":"347.1","Tissue RNA - endometrium 1 [nTPM]":"656.6","Tissue RNA - epididymis [nTPM]":"421.5","Tissue RNA - esophagus [nTPM]":"623.0","Tissue RNA - fallopian tube [nTPM]":"596.1","Tissue RNA - gallbladder [nTPM]":"355.4","Tissue RNA - heart muscle [nTPM]":"336.7","Tissue RNA - hippocampal formation [nTPM]":"169.0","Tissue RNA - hypothalamus [nTPM]":"210.7","Tissue RNA - kidney [nTPM]":"375.3","Tissue RNA - liver [nTPM]":"370.3","Tissue RNA - lung [nTPM]":"364.5","Tissue RNA - lymph node [nTPM]":"777.0","Tissue RNA - medulla oblongata [nTPM]":"196.2","Tissue RNA - midbrain [nTPM]":"188.6","Tissue RNA - ovary [nTPM]":"1384.6","Tissue RNA - pancreas [nTPM]":"810.6","Tissue RNA - parathyroid gland [nTPM]":"278.0","Tissue RNA - pituitary gland [nTPM]":"314.4","Tissue RNA - placenta [nTPM]":"423.7","Tissue RNA - pons [nTPM]":"207.5","Tissue RNA - prostate [nTPM]":"386.2","Tissue RNA - rectum [nTPM]":"421.2","Tissue RNA - retina [nTPM]":"161.3","Tissue RNA - salivary gland [nTPM]":"385.2","Tissue RNA - seminal vesicle [nTPM]":"318.5","Tissue RNA - skeletal muscle [nTPM]":"450.9","Tissue RNA - skin 1 [nTPM]":"386.6","Tissue RNA - small intestine [nTPM]":"374.1","Tissue RNA - smooth muscle [nTPM]":"436.0","Tissue RNA - spinal cord [nTPM]":"213.9","Tissue RNA - spleen [nTPM]":"358.1","Tissue RNA - stomach 1 [nTPM]":"467.8","Tissue RNA - testis [nTPM]":"284.7","Tissue RNA - thalamus [nTPM]":"202.6","Tissue RNA - thymus [nTPM]":"683.3","Tissue RNA - thyroid gland [nTPM]":"510.1","Tissue RNA - tongue [nTPM]":"282.4","Tissue RNA - tonsil [nTPM]":"761.7","Tissue RNA - urinary bladder [nTPM]":"524.9","Tissue RNA - vagina [nTPM]":"565.4","Tissue RNA - white matter [nTPM]":"204.5","Cell RNA - A-431 [nTPM]":"2476.2","Cell RNA - A549 [nTPM]":"1522.7","Cell RNA - AF22 [nTPM]":"1864.0","Cell RNA - AN3-CA [nTPM]":"2663.1","Cell RNA - ASC diff [nTPM]":"1073.3","Cell RNA - ASC TERT1 [nTPM]":"1915.6","Cell RNA - BEWO [nTPM]":"2736.9","Cell RNA - BJ [nTPM]":"2111.3","Cell RNA - BJ hTERT+ [nTPM]":"1826.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2678.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2387.2","Cell RNA - CACO-2 [nTPM]":"3640.2","Cell RNA - CAPAN-2 [nTPM]":"1622.2","Cell RNA - Daudi [nTPM]":"6243.9","Cell RNA - EFO-21 [nTPM]":"1683.2","Cell RNA - fHDF\/TERT166 [nTPM]":"1194.5","Cell RNA - GAMG [nTPM]":"1927.6","Cell RNA - HaCaT [nTPM]":"1386.6","Cell RNA - HAP1 [nTPM]":"2552.2","Cell RNA - HBEC3-KT [nTPM]":"4639.2","Cell RNA - HBF TERT88 [nTPM]":"3423.4","Cell RNA - HDLM-2 [nTPM]":"2027.9","Cell RNA - HEK 293 [nTPM]":"2027.3","Cell RNA - HEL [nTPM]":"2149.1","Cell RNA - HeLa [nTPM]":"1361.9","Cell RNA - Hep G2 [nTPM]":"2740.2","Cell RNA - HHSteC [nTPM]":"1593.2","Cell RNA - HL-60 [nTPM]":"4556.3","Cell RNA - HMC-1 [nTPM]":"1790.7","Cell RNA - HSkMC [nTPM]":"1732.2","Cell RNA - hTCEpi [nTPM]":"1559.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"1845.8","Cell RNA - hTERT-HME1 [nTPM]":"3572.3","Cell RNA - hTERT-RPE1 [nTPM]":"2184.3","Cell RNA - HUVEC TERT2 [nTPM]":"2019.4","Cell RNA - JURKAT [nTPM]":"1460.9","Cell RNA - K-562 [nTPM]":"2712.8","Cell RNA - Karpas-707 [nTPM]":"1406.5","Cell RNA - LHCN-M2 [nTPM]":"1945.5","Cell RNA - MCF7 [nTPM]":"2826.5","Cell RNA - MOLT-4 [nTPM]":"3071.1","Cell RNA - NB-4 [nTPM]":"3087.4","Cell RNA - NTERA-2 [nTPM]":"2400.7","Cell RNA - OE19 [nTPM]":"1280.7","Cell RNA - PC-3 [nTPM]":"1857.2","Cell RNA - REH [nTPM]":"2695.2","Cell RNA - RH-30 [nTPM]":"2051.7","Cell RNA - RPMI-8226 [nTPM]":"3241.9","Cell RNA - RPTEC TERT1 [nTPM]":"2306.9","Cell RNA - RT4 [nTPM]":"1583.1","Cell RNA - SCLC-21H [nTPM]":"1433.8","Cell RNA - SH-SY5Y [nTPM]":"1167.4","Cell RNA - SiHa [nTPM]":"1210.6","Cell RNA - SK-BR-3 [nTPM]":"2084.4","Cell RNA - SK-MEL-30 [nTPM]":"4091.0","Cell RNA - SuSa [nTPM]":"1288.7","Cell RNA - T-47d [nTPM]":"2513.8","Cell RNA - THP-1 [nTPM]":"2000.7","Cell RNA - TIME [nTPM]":"1289.5","Cell RNA - U-138 MG [nTPM]":"916.7","Cell RNA - U-2 OS [nTPM]":"2114.4","Cell RNA - U-2197 [nTPM]":"1082.5","Cell RNA - U-251 MG [nTPM]":"3705.3","Cell RNA - U-266\/70 [nTPM]":"1161.5","Cell RNA - U-266\/84 [nTPM]":"2139.6","Cell RNA - U-698 [nTPM]":"3702.2","Cell RNA - U-87 MG [nTPM]":"1403.3","Cell RNA - U-937 [nTPM]":"3561.5","Cell RNA - WM-115 [nTPM]":"1897.0","Blood RNA - basophil [nTPM]":"153.6","Blood RNA - classical monocyte [nTPM]":"287.1","Blood RNA - eosinophil [nTPM]":"92.3","Blood RNA - gdT-cell [nTPM]":"443.1","Blood RNA - intermediate monocyte [nTPM]":"311.4","Blood RNA - MAIT T-cell [nTPM]":"834.2","Blood RNA - memory B-cell [nTPM]":"847.9","Blood RNA - memory CD4 T-cell [nTPM]":"832.8","Blood RNA - memory CD8 T-cell [nTPM]":"654.3","Blood RNA - myeloid DC [nTPM]":"564.2","Blood RNA - naive B-cell [nTPM]":"634.9","Blood RNA - naive CD4 T-cell [nTPM]":"1189.9","Blood RNA - naive CD8 T-cell [nTPM]":"973.4","Blood RNA - neutrophil [nTPM]":"38.0","Blood RNA - NK-cell [nTPM]":"656.2","Blood RNA - non-classical monocyte [nTPM]":"264.4","Blood RNA - plasmacytoid DC [nTPM]":"516.8","Blood RNA - T-reg [nTPM]":"782.6","Blood RNA - total PBMC [nTPM]":"1076.1","Brain RNA - amygdala [nTPM]":"180.7","Brain RNA - basal ganglia [nTPM]":"190.3","Brain RNA - cerebellum [nTPM]":"188.6","Brain RNA - cerebral cortex [nTPM]":"233.5","Brain RNA - hippocampal formation [nTPM]":"169.0","Brain RNA - hypothalamus [nTPM]":"210.7","Brain RNA - medulla oblongata [nTPM]":"196.2","Brain RNA - midbrain [nTPM]":"188.6","Brain RNA - pons [nTPM]":"207.5","Brain RNA - spinal cord [nTPM]":"213.9","Brain RNA - thalamus [nTPM]":"202.6","Brain RNA - white matter [nTPM]":"204.5","Single Cell Type RNA - Adipocytes [nTPM]":"462.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"346.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"461.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"911.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1400.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1224.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1692.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"993.1","Single Cell Type RNA - Bipolar cells [nTPM]":"177.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"779.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1045.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"243.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"514.8","Single Cell Type RNA - Club cells [nTPM]":"764.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"323.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1647.8","Single Cell Type RNA - dendritic cells [nTPM]":"615.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"175.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"743.4","Single Cell Type RNA - Ductal cells [nTPM]":"1073.6","Single Cell Type RNA - Early spermatids [nTPM]":"135.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"466.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"707.3","Single Cell Type RNA - Endothelial cells [nTPM]":"568.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"362.1","Single Cell Type RNA - Erythroid cells [nTPM]":"865.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"919.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2021.0","Single Cell Type RNA - Fibroblasts [nTPM]":"685.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"489.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"544.6","Single Cell Type RNA - granulocytes [nTPM]":"443.8","Single Cell Type RNA - Granulosa cells [nTPM]":"688.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"383.8","Single Cell Type RNA - Hepatocytes [nTPM]":"254.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"1071.0","Single Cell Type RNA - Horizontal cells [nTPM]":"127.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"20.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"656.0","Single Cell Type RNA - Ionocytes [nTPM]":"679.5","Single Cell Type RNA - Kupffer cells [nTPM]":"629.2","Single Cell Type RNA - Langerhans cells [nTPM]":"817.6","Single Cell Type RNA - Late spermatids [nTPM]":"98.6","Single Cell Type RNA - Leydig cells [nTPM]":"974.9","Single Cell Type RNA - Macrophages [nTPM]":"557.2","Single Cell Type RNA - Melanocytes [nTPM]":"610.1","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"862.8","Single Cell Type RNA - Muller glia cells [nTPM]":"339.2","Single Cell Type RNA - NK-cells [nTPM]":"476.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"14.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"922.5","Single Cell Type RNA - Paneth cells [nTPM]":"370.1","Single Cell Type RNA - Peritubular cells [nTPM]":"649.9","Single Cell Type RNA - Plasma cells [nTPM]":"671.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1051.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"404.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"911.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"357.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"144.1","Single Cell Type RNA - Sertoli cells [nTPM]":"433.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"617.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1074.1","Single Cell Type RNA - Spermatocytes [nTPM]":"855.7","Single Cell Type RNA - Spermatogonia [nTPM]":"578.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"907.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1019.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1538.8","Single Cell Type RNA - T-cells [nTPM]":"865.1","Single Cell Type RNA - Theca cells [nTPM]":"1019.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"866.2","Single Cell Type RNA - Urothelial cells [nTPM]":"967.3"},{"Gene":"NR4A3","Gene synonym":["CHN","CSMF","MINOR","NOR1"],"Ensembl":"ENSG00000119508","Gene description":"Nuclear receptor subfamily 4 group A member 3","Uniprot":["Q92570"],"Chromosome":"9","Position":"99821855-99866891","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"305.7","Langerhans cells":"417.5","Macrophages":"172.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"BJ hTERT+":"24.1","HeLa":"8.0","SK-MEL-30":"18.5","U-266\/70":"9.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043360"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 38: Heart - Muscle contraction","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043360":"AB_10961186"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.97e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.92e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.34e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.46e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.30e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.30e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.11e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Tissue RNA - adipose tissue [nTPM]":"43.2","Tissue RNA - adrenal gland [nTPM]":"61.2","Tissue RNA - amygdala [nTPM]":"3.4","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"6.3","Tissue RNA - bone marrow [nTPM]":"32.7","Tissue RNA - breast [nTPM]":"7.4","Tissue RNA - cerebellum [nTPM]":"14.1","Tissue RNA - cerebral cortex [nTPM]":"5.5","Tissue RNA - cervix [nTPM]":"11.4","Tissue RNA - choroid plexus [nTPM]":"4.2","Tissue RNA - colon [nTPM]":"9.8","Tissue RNA - duodenum [nTPM]":"0.7","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"4.0","Tissue RNA - fallopian tube [nTPM]":"24.8","Tissue RNA - gallbladder [nTPM]":"23.5","Tissue RNA - heart muscle [nTPM]":"67.2","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"7.4","Tissue RNA - kidney [nTPM]":"7.8","Tissue RNA - liver [nTPM]":"9.0","Tissue RNA - lung [nTPM]":"19.6","Tissue RNA - lymph node [nTPM]":"1.3","Tissue RNA - medulla oblongata [nTPM]":"6.3","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"46.8","Tissue RNA - pancreas [nTPM]":"5.2","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"21.2","Tissue RNA - placenta [nTPM]":"6.5","Tissue RNA - pons [nTPM]":"5.9","Tissue RNA - prostate [nTPM]":"15.6","Tissue RNA - rectum [nTPM]":"4.0","Tissue RNA - retina [nTPM]":"8.7","Tissue RNA - salivary gland [nTPM]":"2.4","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"62.8","Tissue RNA - skin 1 [nTPM]":"2.4","Tissue RNA - small intestine [nTPM]":"5.8","Tissue RNA - smooth muscle [nTPM]":"13.4","Tissue RNA - spinal cord [nTPM]":"1.1","Tissue RNA - spleen [nTPM]":"3.5","Tissue RNA - stomach 1 [nTPM]":"13.7","Tissue RNA - testis [nTPM]":"1.0","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"7.2","Tissue RNA - tongue [nTPM]":"6.2","Tissue RNA - tonsil [nTPM]":"0.9","Tissue RNA - urinary bladder [nTPM]":"32.8","Tissue RNA - vagina [nTPM]":"5.1","Tissue RNA - white matter [nTPM]":"2.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.7","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"1.3","Cell RNA - ASC TERT1 [nTPM]":"0.4","Cell RNA - BEWO [nTPM]":"1.1","Cell RNA - BJ [nTPM]":"1.5","Cell RNA - BJ hTERT+ [nTPM]":"24.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.2","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.2","Cell RNA - EFO-21 [nTPM]":"0.3","Cell RNA - fHDF\/TERT166 [nTPM]":"0.7","Cell RNA - GAMG [nTPM]":"0.5","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"1.8","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"8.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.2","Cell RNA - HL-60 [nTPM]":"0.1","Cell RNA - HMC-1 [nTPM]":"2.3","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.5","Cell RNA - hTERT-HME1 [nTPM]":"0.1","Cell RNA - hTERT-RPE1 [nTPM]":"0.1","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.5","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.7","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.6","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"1.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.4","Cell RNA - SH-SY5Y [nTPM]":"0.4","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"2.0","Cell RNA - SK-MEL-30 [nTPM]":"18.5","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"1.4","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"1.8","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"9.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.9","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.9","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.4","Brain RNA - basal ganglia [nTPM]":"6.3","Brain RNA - cerebellum [nTPM]":"14.1","Brain RNA - cerebral cortex [nTPM]":"5.5","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"7.4","Brain RNA - medulla oblongata [nTPM]":"6.3","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"5.9","Brain RNA - spinal cord [nTPM]":"1.1","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"2.3","Single Cell Type RNA - Adipocytes [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.7","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"101.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"79.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"97.9","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"44.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"305.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"10.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"10.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"91.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"93.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"12.8","Single Cell Type RNA - Endothelial cells [nTPM]":"16.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"27.3","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"13.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.2","Single Cell Type RNA - Fibroblasts [nTPM]":"60.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"124.3","Single Cell Type RNA - granulocytes [nTPM]":"120.7","Single Cell Type RNA - Granulosa cells [nTPM]":"1.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.5","Single Cell Type RNA - Hepatocytes [nTPM]":"0.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"6.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.8","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"12.3","Single Cell Type RNA - Langerhans cells [nTPM]":"417.5","Single Cell Type RNA - Late spermatids [nTPM]":"2.4","Single Cell Type RNA - Leydig cells [nTPM]":"1.5","Single Cell Type RNA - Macrophages [nTPM]":"172.8","Single Cell Type RNA - Melanocytes [nTPM]":"88.9","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"43.0","Single Cell Type RNA - Muller glia cells [nTPM]":"3.6","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.2","Single Cell Type RNA - Paneth cells [nTPM]":"2.3","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"37.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"11.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"35.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"75.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"59.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"5.6","Single Cell Type RNA - T-cells [nTPM]":"69.6","Single Cell Type RNA - Theca cells [nTPM]":"1.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.7","Single Cell Type RNA - Urothelial cells [nTPM]":"3.4"},{"Gene":"NRAS","Gene synonym":["N-ras"],"Ensembl":"ENSG00000213281","Gene description":"NRAS proto-oncogene, GTPase","Uniprot":["P01111"],"Chromosome":"1","Position":"114704469-114716771","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB010157","HPA049830","CAB079912"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 53: Non-specific - Cell cycle regulation","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 16: Pancreatic endocrine cells - Mixed function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010157":"AB_632073","CAB079912":"AB_2784586","HPA049830":"AB_2680903"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.03e-7"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.76e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.36e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.87e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.33e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.0","Tissue RNA - adrenal gland [nTPM]":"9.1","Tissue RNA - amygdala [nTPM]":"10.3","Tissue RNA - appendix [nTPM]":"25.7","Tissue RNA - basal ganglia [nTPM]":"11.2","Tissue RNA - bone marrow [nTPM]":"58.5","Tissue RNA - breast [nTPM]":"18.0","Tissue RNA - cerebellum [nTPM]":"11.5","Tissue RNA - cerebral cortex [nTPM]":"12.3","Tissue RNA - cervix [nTPM]":"12.5","Tissue RNA - choroid plexus [nTPM]":"8.6","Tissue RNA - colon [nTPM]":"27.8","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"12.4","Tissue RNA - epididymis [nTPM]":"7.8","Tissue RNA - esophagus [nTPM]":"20.7","Tissue RNA - fallopian tube [nTPM]":"10.3","Tissue RNA - gallbladder [nTPM]":"17.2","Tissue RNA - heart muscle [nTPM]":"8.3","Tissue RNA - hippocampal formation [nTPM]":"10.2","Tissue RNA - hypothalamus [nTPM]":"12.2","Tissue RNA - kidney [nTPM]":"20.9","Tissue RNA - liver [nTPM]":"24.9","Tissue RNA - lung [nTPM]":"18.5","Tissue RNA - lymph node [nTPM]":"30.4","Tissue RNA - medulla oblongata [nTPM]":"12.3","Tissue RNA - midbrain [nTPM]":"12.1","Tissue RNA - ovary [nTPM]":"9.6","Tissue RNA - pancreas [nTPM]":"11.4","Tissue RNA - parathyroid gland [nTPM]":"9.0","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"28.3","Tissue RNA - pons [nTPM]":"12.3","Tissue RNA - prostate [nTPM]":"11.4","Tissue RNA - rectum [nTPM]":"26.6","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"10.9","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"7.7","Tissue RNA - skin 1 [nTPM]":"19.8","Tissue RNA - small intestine [nTPM]":"22.5","Tissue RNA - smooth muscle [nTPM]":"14.1","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"18.6","Tissue RNA - stomach 1 [nTPM]":"21.8","Tissue RNA - testis [nTPM]":"9.6","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"39.0","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"7.8","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"22.2","Tissue RNA - vagina [nTPM]":"8.6","Tissue RNA - white matter [nTPM]":"13.4","Cell RNA - A-431 [nTPM]":"93.7","Cell RNA - A549 [nTPM]":"24.9","Cell RNA - AF22 [nTPM]":"65.2","Cell RNA - AN3-CA [nTPM]":"24.9","Cell RNA - ASC diff [nTPM]":"26.4","Cell RNA - ASC TERT1 [nTPM]":"56.3","Cell RNA - BEWO [nTPM]":"46.5","Cell RNA - BJ [nTPM]":"43.5","Cell RNA - BJ hTERT+ [nTPM]":"48.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"79.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"89.0","Cell RNA - CACO-2 [nTPM]":"50.4","Cell RNA - CAPAN-2 [nTPM]":"33.9","Cell RNA - Daudi [nTPM]":"70.4","Cell RNA - EFO-21 [nTPM]":"56.3","Cell RNA - fHDF\/TERT166 [nTPM]":"58.9","Cell RNA - GAMG [nTPM]":"55.4","Cell RNA - HaCaT [nTPM]":"26.0","Cell RNA - HAP1 [nTPM]":"88.2","Cell RNA - HBEC3-KT [nTPM]":"70.6","Cell RNA - HBF TERT88 [nTPM]":"113.4","Cell RNA - HDLM-2 [nTPM]":"96.5","Cell RNA - HEK 293 [nTPM]":"34.2","Cell RNA - HEL [nTPM]":"47.8","Cell RNA - HeLa [nTPM]":"34.5","Cell RNA - Hep G2 [nTPM]":"60.2","Cell RNA - HHSteC [nTPM]":"52.3","Cell RNA - HL-60 [nTPM]":"120.0","Cell RNA - HMC-1 [nTPM]":"71.0","Cell RNA - HSkMC [nTPM]":"51.1","Cell RNA - hTCEpi [nTPM]":"56.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"91.5","Cell RNA - hTERT-HME1 [nTPM]":"66.2","Cell RNA - hTERT-RPE1 [nTPM]":"25.0","Cell RNA - HUVEC TERT2 [nTPM]":"102.8","Cell RNA - JURKAT [nTPM]":"54.6","Cell RNA - K-562 [nTPM]":"77.3","Cell RNA - Karpas-707 [nTPM]":"78.5","Cell RNA - LHCN-M2 [nTPM]":"71.0","Cell RNA - MCF7 [nTPM]":"248.9","Cell RNA - MOLT-4 [nTPM]":"83.5","Cell RNA - NB-4 [nTPM]":"46.4","Cell RNA - NTERA-2 [nTPM]":"111.0","Cell RNA - OE19 [nTPM]":"30.2","Cell RNA - PC-3 [nTPM]":"17.9","Cell RNA - REH [nTPM]":"62.9","Cell RNA - RH-30 [nTPM]":"116.0","Cell RNA - RPMI-8226 [nTPM]":"44.1","Cell RNA - RPTEC TERT1 [nTPM]":"70.6","Cell RNA - RT4 [nTPM]":"49.5","Cell RNA - SCLC-21H [nTPM]":"39.4","Cell RNA - SH-SY5Y [nTPM]":"59.0","Cell RNA - SiHa [nTPM]":"44.7","Cell RNA - SK-BR-3 [nTPM]":"36.4","Cell RNA - SK-MEL-30 [nTPM]":"107.1","Cell RNA - SuSa [nTPM]":"75.4","Cell RNA - T-47d [nTPM]":"31.9","Cell RNA - THP-1 [nTPM]":"96.2","Cell RNA - TIME [nTPM]":"79.2","Cell RNA - U-138 MG [nTPM]":"43.3","Cell RNA - U-2 OS [nTPM]":"82.2","Cell RNA - U-2197 [nTPM]":"81.5","Cell RNA - U-251 MG [nTPM]":"90.3","Cell RNA - U-266\/70 [nTPM]":"137.7","Cell RNA - U-266\/84 [nTPM]":"101.6","Cell RNA - U-698 [nTPM]":"81.6","Cell RNA - U-87 MG [nTPM]":"86.4","Cell RNA - U-937 [nTPM]":"64.6","Cell RNA - WM-115 [nTPM]":"159.0","Blood RNA - basophil [nTPM]":"38.7","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"12.6","Blood RNA - gdT-cell [nTPM]":"11.7","Blood RNA - intermediate monocyte [nTPM]":"19.2","Blood RNA - MAIT T-cell [nTPM]":"10.5","Blood RNA - memory B-cell [nTPM]":"12.8","Blood RNA - memory CD4 T-cell [nTPM]":"9.3","Blood RNA - memory CD8 T-cell [nTPM]":"11.6","Blood RNA - myeloid DC [nTPM]":"12.6","Blood RNA - naive B-cell [nTPM]":"10.5","Blood RNA - naive CD4 T-cell [nTPM]":"9.9","Blood RNA - naive CD8 T-cell [nTPM]":"12.9","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"15.5","Blood RNA - non-classical monocyte [nTPM]":"17.6","Blood RNA - plasmacytoid DC [nTPM]":"9.6","Blood RNA - T-reg [nTPM]":"13.4","Blood RNA - total PBMC [nTPM]":"13.1","Brain RNA - amygdala [nTPM]":"10.3","Brain RNA - basal ganglia [nTPM]":"11.2","Brain RNA - cerebellum [nTPM]":"11.5","Brain RNA - cerebral cortex [nTPM]":"12.3","Brain RNA - hippocampal formation [nTPM]":"10.2","Brain RNA - hypothalamus [nTPM]":"12.2","Brain RNA - medulla oblongata [nTPM]":"12.3","Brain RNA - midbrain [nTPM]":"12.1","Brain RNA - pons [nTPM]":"12.3","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"13.4","Single Cell Type RNA - Adipocytes [nTPM]":"22.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"16.5","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"25.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"30.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"15.4","Single Cell Type RNA - Bipolar cells [nTPM]":"5.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - dendritic cells [nTPM]":"27.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"49.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"13.7","Single Cell Type RNA - Ductal cells [nTPM]":"34.1","Single Cell Type RNA - Early spermatids [nTPM]":"3.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"24.7","Single Cell Type RNA - Endothelial cells [nTPM]":"29.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"24.6","Single Cell Type RNA - Erythroid cells [nTPM]":"31.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"50.4","Single Cell Type RNA - Fibroblasts [nTPM]":"16.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.0","Single Cell Type RNA - granulocytes [nTPM]":"31.1","Single Cell Type RNA - Granulosa cells [nTPM]":"22.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.2","Single Cell Type RNA - Hepatocytes [nTPM]":"29.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.2","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"28.1","Single Cell Type RNA - Ionocytes [nTPM]":"30.5","Single Cell Type RNA - Kupffer cells [nTPM]":"44.9","Single Cell Type RNA - Langerhans cells [nTPM]":"30.7","Single Cell Type RNA - Late spermatids [nTPM]":"5.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"30.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"41.6","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"51.4","Single Cell Type RNA - Paneth cells [nTPM]":"32.9","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"39.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"12.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"15.3","Single Cell Type RNA - Spermatocytes [nTPM]":"7.3","Single Cell Type RNA - Spermatogonia [nTPM]":"15.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"24.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"36.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"21.9","Single Cell Type RNA - Theca cells [nTPM]":"13.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"28.8","Single Cell Type RNA - Urothelial cells [nTPM]":"40.2"},{"Gene":"NSD2","Gene synonym":["KMT3G","MMSET","WHSC1"],"Ensembl":"ENSG00000109685","Gene description":"Nuclear receptor binding SET domain protein 2","Uniprot":["O96028"],"Chromosome":"4","Position":"1871393-1982207","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Methyltransferase","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Glandular and luminal cells":"20.3","Granulosa cells":"69.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA015801","CAB068246","CAB068247"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB068246":"AB_2665690","CAB068247":"AB_2665689","HPA015801":"AB_1858830"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.61e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.66e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.25e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.19e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.89e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.15e-2"},"Tissue RNA - adipose tissue [nTPM]":"10.1","Tissue RNA - adrenal gland [nTPM]":"8.4","Tissue RNA - amygdala [nTPM]":"12.7","Tissue RNA - appendix [nTPM]":"16.5","Tissue RNA - basal ganglia [nTPM]":"13.0","Tissue RNA - bone marrow [nTPM]":"54.9","Tissue RNA - breast [nTPM]":"9.9","Tissue RNA - cerebellum [nTPM]":"23.6","Tissue RNA - cerebral cortex [nTPM]":"15.2","Tissue RNA - cervix [nTPM]":"9.4","Tissue RNA - choroid plexus [nTPM]":"0.8","Tissue RNA - colon [nTPM]":"19.6","Tissue RNA - duodenum [nTPM]":"18.6","Tissue RNA - endometrium 1 [nTPM]":"10.7","Tissue RNA - epididymis [nTPM]":"7.3","Tissue RNA - esophagus [nTPM]":"13.6","Tissue RNA - fallopian tube [nTPM]":"8.4","Tissue RNA - gallbladder [nTPM]":"8.3","Tissue RNA - heart muscle [nTPM]":"15.8","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"11.5","Tissue RNA - kidney [nTPM]":"9.8","Tissue RNA - liver [nTPM]":"8.3","Tissue RNA - lung [nTPM]":"12.6","Tissue RNA - lymph node [nTPM]":"25.4","Tissue RNA - medulla oblongata [nTPM]":"9.8","Tissue RNA - midbrain [nTPM]":"8.6","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"13.5","Tissue RNA - parathyroid gland [nTPM]":"12.0","Tissue RNA - pituitary gland [nTPM]":"13.8","Tissue RNA - placenta [nTPM]":"12.2","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"9.7","Tissue RNA - rectum [nTPM]":"22.5","Tissue RNA - retina [nTPM]":"28.5","Tissue RNA - salivary gland [nTPM]":"11.6","Tissue RNA - seminal vesicle [nTPM]":"8.4","Tissue RNA - skeletal muscle [nTPM]":"16.7","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"18.3","Tissue RNA - smooth muscle [nTPM]":"12.4","Tissue RNA - spinal cord [nTPM]":"4.4","Tissue RNA - spleen [nTPM]":"14.1","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"37.2","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"59.8","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"13.7","Tissue RNA - tonsil [nTPM]":"24.3","Tissue RNA - urinary bladder [nTPM]":"9.7","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"124.0","Cell RNA - A549 [nTPM]":"58.6","Cell RNA - AF22 [nTPM]":"168.3","Cell RNA - AN3-CA [nTPM]":"71.2","Cell RNA - ASC diff [nTPM]":"17.5","Cell RNA - ASC TERT1 [nTPM]":"26.5","Cell RNA - BEWO [nTPM]":"44.2","Cell RNA - BJ [nTPM]":"98.2","Cell RNA - BJ hTERT+ [nTPM]":"85.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"115.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"128.8","Cell RNA - CACO-2 [nTPM]":"44.6","Cell RNA - CAPAN-2 [nTPM]":"141.4","Cell RNA - Daudi [nTPM]":"117.5","Cell RNA - EFO-21 [nTPM]":"31.4","Cell RNA - fHDF\/TERT166 [nTPM]":"78.0","Cell RNA - GAMG [nTPM]":"158.5","Cell RNA - HaCaT [nTPM]":"50.2","Cell RNA - HAP1 [nTPM]":"114.4","Cell RNA - HBEC3-KT [nTPM]":"74.3","Cell RNA - HBF TERT88 [nTPM]":"195.0","Cell RNA - HDLM-2 [nTPM]":"58.3","Cell RNA - HEK 293 [nTPM]":"47.7","Cell RNA - HEL [nTPM]":"151.3","Cell RNA - HeLa [nTPM]":"81.7","Cell RNA - Hep G2 [nTPM]":"25.5","Cell RNA - HHSteC [nTPM]":"18.6","Cell RNA - HL-60 [nTPM]":"89.5","Cell RNA - HMC-1 [nTPM]":"74.9","Cell RNA - HSkMC [nTPM]":"9.9","Cell RNA - hTCEpi [nTPM]":"19.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"101.2","Cell RNA - hTERT-HME1 [nTPM]":"89.9","Cell RNA - hTERT-RPE1 [nTPM]":"60.1","Cell RNA - HUVEC TERT2 [nTPM]":"92.2","Cell RNA - JURKAT [nTPM]":"123.4","Cell RNA - K-562 [nTPM]":"81.7","Cell RNA - Karpas-707 [nTPM]":"132.2","Cell RNA - LHCN-M2 [nTPM]":"95.8","Cell RNA - MCF7 [nTPM]":"42.1","Cell RNA - MOLT-4 [nTPM]":"243.3","Cell RNA - NB-4 [nTPM]":"99.7","Cell RNA - NTERA-2 [nTPM]":"68.8","Cell RNA - OE19 [nTPM]":"60.1","Cell RNA - PC-3 [nTPM]":"77.1","Cell RNA - REH [nTPM]":"137.8","Cell RNA - RH-30 [nTPM]":"106.7","Cell RNA - RPMI-8226 [nTPM]":"42.9","Cell RNA - RPTEC TERT1 [nTPM]":"45.4","Cell RNA - RT4 [nTPM]":"57.4","Cell RNA - SCLC-21H [nTPM]":"115.6","Cell RNA - SH-SY5Y [nTPM]":"82.7","Cell RNA - SiHa [nTPM]":"78.4","Cell RNA - SK-BR-3 [nTPM]":"29.2","Cell RNA - SK-MEL-30 [nTPM]":"31.7","Cell RNA - SuSa [nTPM]":"71.4","Cell RNA - T-47d [nTPM]":"68.9","Cell RNA - THP-1 [nTPM]":"52.2","Cell RNA - TIME [nTPM]":"64.9","Cell RNA - U-138 MG [nTPM]":"109.0","Cell RNA - U-2 OS [nTPM]":"87.4","Cell RNA - U-2197 [nTPM]":"72.8","Cell RNA - U-251 MG [nTPM]":"188.1","Cell RNA - U-266\/70 [nTPM]":"54.1","Cell RNA - U-266\/84 [nTPM]":"72.9","Cell RNA - U-698 [nTPM]":"113.7","Cell RNA - U-87 MG [nTPM]":"66.0","Cell RNA - U-937 [nTPM]":"81.9","Cell RNA - WM-115 [nTPM]":"108.0","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"1.1","Blood RNA - eosinophil [nTPM]":"1.3","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.8","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"1.2","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"1.7","Blood RNA - naive CD4 T-cell [nTPM]":"1.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"1.2","Blood RNA - non-classical monocyte [nTPM]":"0.5","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"2.9","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"12.7","Brain RNA - basal ganglia [nTPM]":"13.0","Brain RNA - cerebellum [nTPM]":"23.6","Brain RNA - cerebral cortex [nTPM]":"15.2","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"11.5","Brain RNA - medulla oblongata [nTPM]":"9.8","Brain RNA - midbrain [nTPM]":"8.6","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"4.4","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"12.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.4","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"8.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"12.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"15.7","Single Cell Type RNA - dendritic cells [nTPM]":"7.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"11.7","Single Cell Type RNA - Endothelial cells [nTPM]":"6.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.0","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.3","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"69.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"13.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"5.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"5.7","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"4.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"4.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"8.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.4","Single Cell Type RNA - T-cells [nTPM]":"5.2","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NTRK1","Gene synonym":["MTC","TRK","TRKA"],"Ensembl":"ENSG00000198400","Gene description":"Neurotrophic receptor tyrosine kinase 1","Uniprot":["P04629"],"Chromosome":"1","Position":"156815640-156881850","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"7.0","brain":"21.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"10","RNA single cell type specific nTPM":{"Bipolar cells":"22.8","granulocytes":"55.9","Horizontal cells":"57.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"1.3"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebral cortex":"7.6","medulla oblongata":"19.8","pons":"21.7"},"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"116","RNA blood cell specific nTPM":{"basophil":"94.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"768","RNA blood lineage specific nTPM":{"granulocytes":"94.5"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"HMC-1":"82.1"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"basal ganglia":"8.4"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":"6","RNA pig brain regional specific nTPM":{"basal ganglia":"4.1"},"Antibody":["CAB004606","HPA035799","HPA076570"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"79000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 62: Horizontal cells - Visual perception","Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB004606":"AB_628397","HPA035799":"AB_2674788","HPA076570":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.89e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.42e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.18e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.79e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.89e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.8","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"0.7","Tissue RNA - appendix [nTPM]":"0.4","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"0.2","Tissue RNA - cerebellum [nTPM]":"1.8","Tissue RNA - cerebral cortex [nTPM]":"7.6","Tissue RNA - cervix [nTPM]":"0.7","Tissue RNA - choroid plexus [nTPM]":"0.7","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"1.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.1","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.4","Tissue RNA - heart muscle [nTPM]":"1.0","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"3.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.5","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"19.8","Tissue RNA - midbrain [nTPM]":"1.5","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.7","Tissue RNA - placenta [nTPM]":"0.2","Tissue RNA - pons [nTPM]":"21.7","Tissue RNA - prostate [nTPM]":"1.4","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"1.9","Tissue RNA - salivary gland [nTPM]":"0.5","Tissue RNA - seminal vesicle [nTPM]":"0.3","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.3","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"0.2","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.5","Tissue RNA - testis [nTPM]":"1.6","Tissue RNA - thalamus [nTPM]":"0.4","Tissue RNA - thymus [nTPM]":"0.3","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.2","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.3","Tissue RNA - vagina [nTPM]":"0.5","Tissue RNA - white matter [nTPM]":"0.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.1","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"1.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.2","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"11.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"14.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"82.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.2","Cell RNA - K-562 [nTPM]":"4.4","Cell RNA - Karpas-707 [nTPM]":"1.6","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.2","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"2.4","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.5","Cell RNA - REH [nTPM]":"2.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"18.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.3","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"3.5","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"94.5","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.8","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"0.7","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"1.8","Brain RNA - cerebral cortex [nTPM]":"7.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"19.8","Brain RNA - midbrain [nTPM]":"1.5","Brain RNA - pons [nTPM]":"21.7","Brain RNA - spinal cord [nTPM]":"0.2","Brain RNA - thalamus [nTPM]":"0.4","Brain RNA - white matter [nTPM]":"0.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.3","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"4.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"4.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.1","Single Cell Type RNA - granulocytes [nTPM]":"55.9","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"2.8","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.9","Single Cell Type RNA - Spermatocytes [nTPM]":"3.2","Single Cell Type RNA - Spermatogonia [nTPM]":"2.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.0","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"NTRK2","Gene synonym":["TRKB"],"Ensembl":"ENSG00000148053","Gene description":"Neurotrophic receptor tyrosine kinase 2","Uniprot":["Q16620"],"Chromosome":"9","Position":"84668551-85027054","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","Epilepsy","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"230.0","thyroid gland":"116.9"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"1144.3","Excitatory neurons":"750.1","Inhibitory neurons":"877.7","Oligodendrocyte precursor cells":"557.9"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"5","RNA cancer specific FPKM":{"glioma":"31.6","head and neck cancer":"8.0","lung cancer":"9.8","thyroid cancer":"26.4"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"8.7","HaCaT":"3.0","RPTEC TERT1":"9.7","SH-SY5Y":"11.2","SuSa":"4.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA007637","CAB010346","HPA074873"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"20000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuropeptide signaling","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB010346":"AB_2155274","HPA007637":"AB_1080385","HPA074873":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.75e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.26e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.29e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.16e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.39e-3"},"Tissue RNA - adipose tissue [nTPM]":"40.5","Tissue RNA - adrenal gland [nTPM]":"2.7","Tissue RNA - amygdala [nTPM]":"201.9","Tissue RNA - appendix [nTPM]":"1.7","Tissue RNA - basal ganglia [nTPM]":"177.8","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"62.2","Tissue RNA - cerebellum [nTPM]":"133.3","Tissue RNA - cerebral cortex [nTPM]":"190.6","Tissue RNA - cervix [nTPM]":"9.8","Tissue RNA - choroid plexus [nTPM]":"69.8","Tissue RNA - colon [nTPM]":"5.9","Tissue RNA - duodenum [nTPM]":"0.4","Tissue RNA - endometrium 1 [nTPM]":"3.9","Tissue RNA - epididymis [nTPM]":"3.9","Tissue RNA - esophagus [nTPM]":"8.2","Tissue RNA - fallopian tube [nTPM]":"5.6","Tissue RNA - gallbladder [nTPM]":"33.3","Tissue RNA - heart muscle [nTPM]":"15.2","Tissue RNA - hippocampal formation [nTPM]":"173.3","Tissue RNA - hypothalamus [nTPM]":"230.0","Tissue RNA - kidney [nTPM]":"20.4","Tissue RNA - liver [nTPM]":"1.8","Tissue RNA - lung [nTPM]":"10.0","Tissue RNA - lymph node [nTPM]":"3.1","Tissue RNA - medulla oblongata [nTPM]":"119.4","Tissue RNA - midbrain [nTPM]":"218.9","Tissue RNA - ovary [nTPM]":"9.7","Tissue RNA - pancreas [nTPM]":"34.3","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"10.1","Tissue RNA - placenta [nTPM]":"1.8","Tissue RNA - pons [nTPM]":"151.7","Tissue RNA - prostate [nTPM]":"4.7","Tissue RNA - rectum [nTPM]":"3.6","Tissue RNA - retina [nTPM]":"41.2","Tissue RNA - salivary gland [nTPM]":"14.4","Tissue RNA - seminal vesicle [nTPM]":"19.1","Tissue RNA - skeletal muscle [nTPM]":"2.9","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"1.6","Tissue RNA - smooth muscle [nTPM]":"3.3","Tissue RNA - spinal cord [nTPM]":"116.6","Tissue RNA - spleen [nTPM]":"10.9","Tissue RNA - stomach 1 [nTPM]":"1.9","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"222.1","Tissue RNA - thymus [nTPM]":"4.0","Tissue RNA - thyroid gland [nTPM]":"116.9","Tissue RNA - tongue [nTPM]":"13.8","Tissue RNA - tonsil [nTPM]":"4.3","Tissue RNA - urinary bladder [nTPM]":"4.9","Tissue RNA - vagina [nTPM]":"12.0","Tissue RNA - white matter [nTPM]":"117.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"8.7","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"1.4","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"3.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.3","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"1.2","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"9.7","Cell RNA - RT4 [nTPM]":"0.7","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"11.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"4.9","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"2.6","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"201.9","Brain RNA - basal ganglia [nTPM]":"177.8","Brain RNA - cerebellum [nTPM]":"133.3","Brain RNA - cerebral cortex [nTPM]":"190.6","Brain RNA - hippocampal formation [nTPM]":"173.3","Brain RNA - hypothalamus [nTPM]":"230.0","Brain RNA - medulla oblongata [nTPM]":"119.4","Brain RNA - midbrain [nTPM]":"218.9","Brain RNA - pons [nTPM]":"151.7","Brain RNA - spinal cord [nTPM]":"116.6","Brain RNA - thalamus [nTPM]":"222.1","Brain RNA - white matter [nTPM]":"117.7","Single Cell Type RNA - Adipocytes [nTPM]":"17.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1144.3","Single Cell Type RNA - B-cells [nTPM]":"0.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"93.9","Single Cell Type RNA - Bipolar cells [nTPM]":"30.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"144.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"116.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"11.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"1.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"27.4","Single Cell Type RNA - Ductal cells [nTPM]":"36.1","Single Cell Type RNA - Early spermatids [nTPM]":"1.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.4","Single Cell Type RNA - Endothelial cells [nTPM]":"8.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"750.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"76.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"5.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.2","Single Cell Type RNA - Horizontal cells [nTPM]":"242.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"877.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"14.2","Single Cell Type RNA - Late spermatids [nTPM]":"3.6","Single Cell Type RNA - Leydig cells [nTPM]":"104.1","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"17.8","Single Cell Type RNA - Microglial cells [nTPM]":"65.6","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"241.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"557.9","Single Cell Type RNA - Oligodendrocytes [nTPM]":"109.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.5","Single Cell Type RNA - Paneth cells [nTPM]":"7.0","Single Cell Type RNA - Peritubular cells [nTPM]":"48.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"12.2","Single Cell Type RNA - Sertoli cells [nTPM]":"124.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"114.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.8","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"5.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"3.3","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.9"},{"Gene":"NTRK3","Gene synonym":["TRKC"],"Ensembl":"ENSG00000140538","Gene description":"Neurotrophic receptor tyrosine kinase 3","Uniprot":["Q16288"],"Chromosome":"15","Position":"87859751-88256768","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Differentiation","Neurogenesis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"38.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"239.3","Early spermatids":"119.6","Excitatory neurons":"360.0","Inhibitory neurons":"277.8","Late spermatids":"148.9","Microglial cells":"177.1","Oligodendrocyte precursor cells":"499.6"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"2.5","testis cancer":"1.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"U-138 MG":"100.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009233","HPA027484","HPA048065"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear membrane","Nucleoli","Nucleoli rim"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"19000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 10: Brain - Neuronal signaling","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Nucleoli","Nucleoli rim"],"Subcellular additional location":["Nuclear membrane"],"Antibody RRID":{"CAB009233":"AB_632555","HPA027484":"AB_2672297","HPA048065":"AB_2680245"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.34e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.18e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.34e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.91e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.88e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.78e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.45e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-3"},"Tissue RNA - adipose tissue [nTPM]":"12.8","Tissue RNA - adrenal gland [nTPM]":"3.7","Tissue RNA - amygdala [nTPM]":"31.3","Tissue RNA - appendix [nTPM]":"0.8","Tissue RNA - basal ganglia [nTPM]":"33.2","Tissue RNA - bone marrow [nTPM]":"0.1","Tissue RNA - breast [nTPM]":"7.8","Tissue RNA - cerebellum [nTPM]":"30.7","Tissue RNA - cerebral cortex [nTPM]":"34.3","Tissue RNA - cervix [nTPM]":"12.8","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"10.4","Tissue RNA - epididymis [nTPM]":"3.2","Tissue RNA - esophagus [nTPM]":"1.3","Tissue RNA - fallopian tube [nTPM]":"15.0","Tissue RNA - gallbladder [nTPM]":"1.6","Tissue RNA - heart muscle [nTPM]":"5.8","Tissue RNA - hippocampal formation [nTPM]":"38.8","Tissue RNA - hypothalamus [nTPM]":"25.8","Tissue RNA - kidney [nTPM]":"5.1","Tissue RNA - liver [nTPM]":"1.0","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"1.2","Tissue RNA - medulla oblongata [nTPM]":"21.5","Tissue RNA - midbrain [nTPM]":"19.6","Tissue RNA - ovary [nTPM]":"7.2","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"12.2","Tissue RNA - placenta [nTPM]":"1.0","Tissue RNA - pons [nTPM]":"22.1","Tissue RNA - prostate [nTPM]":"9.0","Tissue RNA - rectum [nTPM]":"2.0","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"6.8","Tissue RNA - seminal vesicle [nTPM]":"4.3","Tissue RNA - skeletal muscle [nTPM]":"1.8","Tissue RNA - skin 1 [nTPM]":"4.8","Tissue RNA - small intestine [nTPM]":"2.2","Tissue RNA - smooth muscle [nTPM]":"3.7","Tissue RNA - spinal cord [nTPM]":"10.9","Tissue RNA - spleen [nTPM]":"2.5","Tissue RNA - stomach 1 [nTPM]":"3.2","Tissue RNA - testis [nTPM]":"9.8","Tissue RNA - thalamus [nTPM]":"33.4","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"3.0","Tissue RNA - tongue [nTPM]":"1.9","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"8.7","Tissue RNA - vagina [nTPM]":"7.4","Tissue RNA - white matter [nTPM]":"21.5","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"13.1","Cell RNA - AF22 [nTPM]":"2.7","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.3","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.3","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"2.6","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.9","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"100.6","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"1.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"3.0","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"31.3","Brain RNA - basal ganglia [nTPM]":"33.2","Brain RNA - cerebellum [nTPM]":"30.7","Brain RNA - cerebral cortex [nTPM]":"34.3","Brain RNA - hippocampal formation [nTPM]":"38.8","Brain RNA - hypothalamus [nTPM]":"25.8","Brain RNA - medulla oblongata [nTPM]":"21.5","Brain RNA - midbrain [nTPM]":"19.6","Brain RNA - pons [nTPM]":"22.1","Brain RNA - spinal cord [nTPM]":"10.9","Brain RNA - thalamus [nTPM]":"33.4","Brain RNA - white matter [nTPM]":"21.5","Single Cell Type RNA - Adipocytes [nTPM]":"0.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"239.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"6.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"53.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"119.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"25.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"360.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"5.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.5","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"2.2","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.0","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"277.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"148.9","Single Cell Type RNA - Leydig cells [nTPM]":"3.4","Single Cell Type RNA - Macrophages [nTPM]":"0.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"177.1","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"8.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"499.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"27.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"3.7","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"20.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"40.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"OTX2","Gene synonym":[],"Ensembl":"ENSG00000165588","Gene description":"Orthodenticle homeobox 2","Uniprot":["P32243"],"Chromosome":"14","Position":"56799905-56816693","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Disease variant","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"15","RNA tissue specific nTPM":{"choroid plexus":"108.8","retina":"279.9"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"11","RNA single cell type specific nTPM":{"Bipolar cells":"170.6","Cone photoreceptor cells":"168.9","Rod photoreceptor cells":"202.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"27","RNA cancer specific FPKM":{"testis cancer":"11.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"249.6","hTERT-RPE1":"57.0","NTERA-2":"199.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000633","HPA001123"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 77: Retina - Visual perception","Cell line expression cluster":"Cluster 5: NTERA-2 - Transcription","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA000633":"AB_1079538","HPA001123":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.56e-2"},"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.28e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"4.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"1.3","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"8.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"108.8","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"5.9","Tissue RNA - hypothalamus [nTPM]":"2.6","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"8.7","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"2.5","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"2.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"279.9","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.1","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.1","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"12.8","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.8","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"0.2","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.2","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"249.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"57.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"199.7","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"13.8","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.3","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.1","Brain RNA - basal ganglia [nTPM]":"1.3","Brain RNA - cerebellum [nTPM]":"8.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"5.9","Brain RNA - hypothalamus [nTPM]":"2.6","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"8.7","Brain RNA - pons [nTPM]":"2.0","Brain RNA - spinal cord [nTPM]":"0.1","Brain RNA - thalamus [nTPM]":"12.8","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"170.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"168.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"1.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"16.2","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"202.5","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"0.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"PAX5","Gene synonym":["BSAP"],"Ensembl":"ENSG00000196092","Gene description":"Paired box 5","Uniprot":["Q02548"],"Chromosome":"9","Position":"36833269-37034268","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Spermatogenesis","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"lymphoid tissue":"39.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"29","RNA single cell type specific nTPM":{"B-cells":"91.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"midbrain":"6.5"},"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"43","RNA blood cell specific nTPM":{"memory B-cell":"39.0","naive B-cell":"26.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"52","RNA blood lineage specific nTPM":{"B-cells":"39.0"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"Daudi":"66.6","REH":"194.1","U-698":"87.1"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"11","RNA mouse brain regional specific nTPM":{"midbrain":"3.9"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB026269","CAB026869","HPA056394","HPA068498"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: B-cells - Transcription","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Vesicles","Cytosol"],"Antibody RRID":{"CAB026269":null,"CAB026869":null,"HPA056394":"AB_2683116","HPA068498":"AB_2685997"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.03e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.3","Tissue RNA - adrenal gland [nTPM]":"0.1","Tissue RNA - amygdala [nTPM]":"0.4","Tissue RNA - appendix [nTPM]":"14.9","Tissue RNA - basal ganglia [nTPM]":"0.3","Tissue RNA - bone marrow [nTPM]":"9.4","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.5","Tissue RNA - cerebral cortex [nTPM]":"0.5","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"0.8","Tissue RNA - duodenum [nTPM]":"0.5","Tissue RNA - endometrium 1 [nTPM]":"0.2","Tissue RNA - epididymis [nTPM]":"0.1","Tissue RNA - esophagus [nTPM]":"0.2","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.8","Tissue RNA - heart muscle [nTPM]":"0.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"0.6","Tissue RNA - kidney [nTPM]":"0.1","Tissue RNA - liver [nTPM]":"0.2","Tissue RNA - lung [nTPM]":"0.3","Tissue RNA - lymph node [nTPM]":"39.7","Tissue RNA - medulla oblongata [nTPM]":"1.1","Tissue RNA - midbrain [nTPM]":"6.5","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.2","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"4.1","Tissue RNA - prostate [nTPM]":"0.3","Tissue RNA - rectum [nTPM]":"0.8","Tissue RNA - retina [nTPM]":"0.5","Tissue RNA - salivary gland [nTPM]":"1.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"3.1","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"6.6","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.8","Tissue RNA - spleen [nTPM]":"18.7","Tissue RNA - stomach 1 [nTPM]":"1.6","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"1.9","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"36.2","Tissue RNA - urinary bladder [nTPM]":"1.1","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.3","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"66.6","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.2","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"3.5","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"2.2","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"1.5","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"1.9","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"0.4","Cell RNA - REH [nTPM]":"194.1","Cell RNA - RH-30 [nTPM]":"0.4","Cell RNA - RPMI-8226 [nTPM]":"0.3","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"13.2","Cell RNA - SH-SY5Y [nTPM]":"2.9","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.7","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"7.5","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"87.1","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.1","Blood RNA - memory B-cell [nTPM]":"39.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"26.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.2","Blood RNA - non-classical monocyte [nTPM]":"0.2","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"0.4","Brain RNA - basal ganglia [nTPM]":"0.3","Brain RNA - cerebellum [nTPM]":"0.5","Brain RNA - cerebral cortex [nTPM]":"0.5","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"0.6","Brain RNA - medulla oblongata [nTPM]":"1.1","Brain RNA - midbrain [nTPM]":"6.5","Brain RNA - pons [nTPM]":"4.1","Brain RNA - spinal cord [nTPM]":"0.8","Brain RNA - thalamus [nTPM]":"1.9","Brain RNA - white matter [nTPM]":"0.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"91.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.3","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.9","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.3"},{"Gene":"PAX8","Gene synonym":[],"Ensembl":"ENSG00000125618","Gene description":"Paired box 8","Uniprot":["Q06710"],"Chromosome":"2","Position":"113215997-113278921","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Congenital hypothyroidism","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"11","RNA tissue specific nTPM":{"kidney":"267.9","thyroid gland":"565.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"246.5","Endometrial ciliated cells":"114.0","Glandular and luminal cells":"228.2","Proximal tubular cells":"128.1"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"12","RNA cancer specific FPKM":{"endometrial cancer":"60.6","ovarian cancer":"63.5","renal cancer":"33.2","thyroid cancer":"122.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"7","RNA cell line specific nTPM":{"EFO-21":"79.7","GAMG":"50.0","RPTEC TERT1":"193.2"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"4","RNA mouse brain regional specific nTPM":{"pons and medulla":"5.5"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030062","CAB055097","CAB061888","HPA064554"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - Translation","Tissue expression cluster":"Cluster 7: Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 35: RPTEC-TERT1 - Kidney processes","Single cell expression cluster":"Cluster 44: Endometrium - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB055097":"AB_2236705","CAB061888":"AB_10895719","HPA030062":"AB_10603982","HPA064554":"AB_2685283"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.80e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.24e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.16e-5"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.29e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.13e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.37e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.93e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Tissue RNA - adipose tissue [nTPM]":"2.0","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"0.6","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.5","Tissue RNA - breast [nTPM]":"1.7","Tissue RNA - cerebellum [nTPM]":"0.1","Tissue RNA - cerebral cortex [nTPM]":"1.1","Tissue RNA - cervix [nTPM]":"14.5","Tissue RNA - choroid plexus [nTPM]":"1.7","Tissue RNA - colon [nTPM]":"1.8","Tissue RNA - duodenum [nTPM]":"0.6","Tissue RNA - endometrium 1 [nTPM]":"8.8","Tissue RNA - epididymis [nTPM]":"32.9","Tissue RNA - esophagus [nTPM]":"2.2","Tissue RNA - fallopian tube [nTPM]":"37.5","Tissue RNA - gallbladder [nTPM]":"3.6","Tissue RNA - heart muscle [nTPM]":"2.1","Tissue RNA - hippocampal formation [nTPM]":"1.0","Tissue RNA - hypothalamus [nTPM]":"1.9","Tissue RNA - kidney [nTPM]":"267.9","Tissue RNA - liver [nTPM]":"1.2","Tissue RNA - lung [nTPM]":"1.6","Tissue RNA - lymph node [nTPM]":"1.7","Tissue RNA - medulla oblongata [nTPM]":"5.2","Tissue RNA - midbrain [nTPM]":"1.3","Tissue RNA - ovary [nTPM]":"1.7","Tissue RNA - pancreas [nTPM]":"1.0","Tissue RNA - parathyroid gland [nTPM]":"1.4","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"3.0","Tissue RNA - prostate [nTPM]":"1.1","Tissue RNA - rectum [nTPM]":"0.9","Tissue RNA - retina [nTPM]":"1.5","Tissue RNA - salivary gland [nTPM]":"1.9","Tissue RNA - seminal vesicle [nTPM]":"26.1","Tissue RNA - skeletal muscle [nTPM]":"0.5","Tissue RNA - skin 1 [nTPM]":"1.8","Tissue RNA - small intestine [nTPM]":"2.4","Tissue RNA - smooth muscle [nTPM]":"0.8","Tissue RNA - spinal cord [nTPM]":"3.7","Tissue RNA - spleen [nTPM]":"0.8","Tissue RNA - stomach 1 [nTPM]":"1.4","Tissue RNA - testis [nTPM]":"2.4","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"0.5","Tissue RNA - thyroid gland [nTPM]":"565.5","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"1.0","Tissue RNA - urinary bladder [nTPM]":"2.1","Tissue RNA - vagina [nTPM]":"1.0","Tissue RNA - white matter [nTPM]":"1.9","Cell RNA - A-431 [nTPM]":"9.4","Cell RNA - A549 [nTPM]":"0.8","Cell RNA - AF22 [nTPM]":"0.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.4","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"2.6","Cell RNA - BJ hTERT+ [nTPM]":"8.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.2","Cell RNA - CACO-2 [nTPM]":"5.7","Cell RNA - CAPAN-2 [nTPM]":"1.6","Cell RNA - Daudi [nTPM]":"1.7","Cell RNA - EFO-21 [nTPM]":"79.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.6","Cell RNA - GAMG [nTPM]":"50.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.6","Cell RNA - HBEC3-KT [nTPM]":"2.6","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"3.9","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"1.5","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"3.4","Cell RNA - HHSteC [nTPM]":"0.9","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.6","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"9.9","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"6.2","Cell RNA - LHCN-M2 [nTPM]":"2.5","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"1.0","Cell RNA - NB-4 [nTPM]":"3.8","Cell RNA - NTERA-2 [nTPM]":"0.5","Cell RNA - OE19 [nTPM]":"2.2","Cell RNA - PC-3 [nTPM]":"5.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.6","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"193.2","Cell RNA - RT4 [nTPM]":"14.4","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"10.4","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"5.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"3.5","Cell RNA - TIME [nTPM]":"2.7","Cell RNA - U-138 MG [nTPM]":"13.8","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"2.6","Cell RNA - U-251 MG [nTPM]":"7.2","Cell RNA - U-266\/70 [nTPM]":"1.2","Cell RNA - U-266\/84 [nTPM]":"4.6","Cell RNA - U-698 [nTPM]":"0.6","Cell RNA - U-87 MG [nTPM]":"11.9","Cell RNA - U-937 [nTPM]":"2.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"1.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.1","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.4","Blood RNA - memory B-cell [nTPM]":"1.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.4","Blood RNA - memory CD8 T-cell [nTPM]":"0.3","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"0.5","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.6","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.3","Blood RNA - T-reg [nTPM]":"0.2","Blood RNA - total PBMC [nTPM]":"0.4","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"0.1","Brain RNA - cerebral cortex [nTPM]":"1.1","Brain RNA - hippocampal formation [nTPM]":"1.0","Brain RNA - hypothalamus [nTPM]":"1.9","Brain RNA - medulla oblongata [nTPM]":"5.2","Brain RNA - midbrain [nTPM]":"1.3","Brain RNA - pons [nTPM]":"3.0","Brain RNA - spinal cord [nTPM]":"3.7","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"1.9","Single Cell Type RNA - Adipocytes [nTPM]":"1.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"4.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"1.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"1.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"3.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"246.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.6","Single Cell Type RNA - Distal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"46.9","Single Cell Type RNA - Ductal cells [nTPM]":"8.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"114.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.8","Single Cell Type RNA - Endothelial cells [nTPM]":"1.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.8","Single Cell Type RNA - Erythroid cells [nTPM]":"3.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"2.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.4","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"228.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"1.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.1","Single Cell Type RNA - Hepatocytes [nTPM]":"0.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"5.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.2","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"2.6","Single Cell Type RNA - Langerhans cells [nTPM]":"2.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"5.6","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"2.0","Single Cell Type RNA - Muller glia cells [nTPM]":"4.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"29.2","Single Cell Type RNA - Paneth cells [nTPM]":"7.4","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"6.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"128.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.7","Single Cell Type RNA - Spermatocytes [nTPM]":"6.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"3.1","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.7","Single Cell Type RNA - Urothelial cells [nTPM]":"2.2"},{"Gene":"PBX1","Gene synonym":[],"Ensembl":"ENSG00000185630","Gene description":"PBX homeobox 1","Uniprot":["P40424"],"Chromosome":"1","Position":"164555584-164899296","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Sexual differentiation","Steroidogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"382.3","Excitatory neurons":"475.9","Inhibitory neurons":"405.0","Oligodendrocyte precursor cells":"327.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"93.0","NTERA-2":"111.5","SK-BR-3":"186.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003505","HPA003881","CAB018768"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"CAB018768":"AB_675783","HPA003505":"AB_1855019","HPA003881":"AB_1855020"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.21e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.95e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.24e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.34e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.3","Tissue RNA - adrenal gland [nTPM]":"32.1","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"11.8","Tissue RNA - basal ganglia [nTPM]":"22.3","Tissue RNA - bone marrow [nTPM]":"3.1","Tissue RNA - breast [nTPM]":"36.1","Tissue RNA - cerebellum [nTPM]":"10.7","Tissue RNA - cerebral cortex [nTPM]":"18.0","Tissue RNA - cervix [nTPM]":"88.3","Tissue RNA - choroid plexus [nTPM]":"1.9","Tissue RNA - colon [nTPM]":"52.3","Tissue RNA - duodenum [nTPM]":"22.4","Tissue RNA - endometrium 1 [nTPM]":"136.8","Tissue RNA - epididymis [nTPM]":"21.6","Tissue RNA - esophagus [nTPM]":"30.1","Tissue RNA - fallopian tube [nTPM]":"74.6","Tissue RNA - gallbladder [nTPM]":"37.6","Tissue RNA - heart muscle [nTPM]":"24.0","Tissue RNA - hippocampal formation [nTPM]":"15.3","Tissue RNA - hypothalamus [nTPM]":"14.1","Tissue RNA - kidney [nTPM]":"29.4","Tissue RNA - liver [nTPM]":"7.7","Tissue RNA - lung [nTPM]":"20.7","Tissue RNA - lymph node [nTPM]":"4.5","Tissue RNA - medulla oblongata [nTPM]":"8.8","Tissue RNA - midbrain [nTPM]":"32.7","Tissue RNA - ovary [nTPM]":"52.1","Tissue RNA - pancreas [nTPM]":"48.1","Tissue RNA - parathyroid gland [nTPM]":"29.5","Tissue RNA - pituitary gland [nTPM]":"14.3","Tissue RNA - placenta [nTPM]":"19.5","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"38.0","Tissue RNA - rectum [nTPM]":"19.8","Tissue RNA - retina [nTPM]":"17.1","Tissue RNA - salivary gland [nTPM]":"43.8","Tissue RNA - seminal vesicle [nTPM]":"53.8","Tissue RNA - skeletal muscle [nTPM]":"36.3","Tissue RNA - skin 1 [nTPM]":"10.2","Tissue RNA - small intestine [nTPM]":"19.9","Tissue RNA - smooth muscle [nTPM]":"125.2","Tissue RNA - spinal cord [nTPM]":"13.7","Tissue RNA - spleen [nTPM]":"10.2","Tissue RNA - stomach 1 [nTPM]":"21.9","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"12.6","Tissue RNA - thymus [nTPM]":"10.9","Tissue RNA - thyroid gland [nTPM]":"35.1","Tissue RNA - tongue [nTPM]":"26.5","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"40.2","Tissue RNA - vagina [nTPM]":"41.5","Tissue RNA - white matter [nTPM]":"12.1","Cell RNA - A-431 [nTPM]":"2.9","Cell RNA - A549 [nTPM]":"74.4","Cell RNA - AF22 [nTPM]":"82.4","Cell RNA - AN3-CA [nTPM]":"19.1","Cell RNA - ASC diff [nTPM]":"50.8","Cell RNA - ASC TERT1 [nTPM]":"23.3","Cell RNA - BEWO [nTPM]":"3.4","Cell RNA - BJ [nTPM]":"25.2","Cell RNA - BJ hTERT+ [nTPM]":"20.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"8.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.1","Cell RNA - CACO-2 [nTPM]":"14.2","Cell RNA - CAPAN-2 [nTPM]":"11.8","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"5.5","Cell RNA - fHDF\/TERT166 [nTPM]":"47.8","Cell RNA - GAMG [nTPM]":"4.3","Cell RNA - HaCaT [nTPM]":"22.8","Cell RNA - HAP1 [nTPM]":"31.7","Cell RNA - HBEC3-KT [nTPM]":"8.1","Cell RNA - HBF TERT88 [nTPM]":"3.6","Cell RNA - HDLM-2 [nTPM]":"3.1","Cell RNA - HEK 293 [nTPM]":"31.3","Cell RNA - HEL [nTPM]":"93.0","Cell RNA - HeLa [nTPM]":"56.5","Cell RNA - Hep G2 [nTPM]":"0.3","Cell RNA - HHSteC [nTPM]":"34.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"22.2","Cell RNA - HSkMC [nTPM]":"24.4","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"5.4","Cell RNA - hTERT-HME1 [nTPM]":"2.1","Cell RNA - hTERT-RPE1 [nTPM]":"19.2","Cell RNA - HUVEC TERT2 [nTPM]":"0.3","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.2","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"2.2","Cell RNA - MCF7 [nTPM]":"47.1","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"111.5","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"4.5","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"21.6","Cell RNA - RPMI-8226 [nTPM]":"27.0","Cell RNA - RPTEC TERT1 [nTPM]":"6.3","Cell RNA - RT4 [nTPM]":"44.1","Cell RNA - SCLC-21H [nTPM]":"2.5","Cell RNA - SH-SY5Y [nTPM]":"39.6","Cell RNA - SiHa [nTPM]":"27.8","Cell RNA - SK-BR-3 [nTPM]":"186.1","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"71.4","Cell RNA - T-47d [nTPM]":"73.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.5","Cell RNA - U-138 MG [nTPM]":"3.7","Cell RNA - U-2 OS [nTPM]":"8.6","Cell RNA - U-2197 [nTPM]":"24.2","Cell RNA - U-251 MG [nTPM]":"8.1","Cell RNA - U-266\/70 [nTPM]":"8.5","Cell RNA - U-266\/84 [nTPM]":"61.2","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"0.4","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.4","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.1","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.6","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"22.3","Brain RNA - cerebellum [nTPM]":"10.7","Brain RNA - cerebral cortex [nTPM]":"18.0","Brain RNA - hippocampal formation [nTPM]":"15.3","Brain RNA - hypothalamus [nTPM]":"14.1","Brain RNA - medulla oblongata [nTPM]":"8.8","Brain RNA - midbrain [nTPM]":"32.7","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"13.7","Brain RNA - thalamus [nTPM]":"12.6","Brain RNA - white matter [nTPM]":"12.1","Single Cell Type RNA - Adipocytes [nTPM]":"28.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.6","Single Cell Type RNA - Astrocytes [nTPM]":"382.3","Single Cell Type RNA - B-cells [nTPM]":"2.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"115.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"39.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"70.6","Single Cell Type RNA - Bipolar cells [nTPM]":"39.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"129.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"87.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"50.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"98.7","Single Cell Type RNA - Club cells [nTPM]":"25.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"33.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"110.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.3","Single Cell Type RNA - dendritic cells [nTPM]":"1.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"29.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"47.9","Single Cell Type RNA - Early spermatids [nTPM]":"91.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"47.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"144.3","Single Cell Type RNA - Endothelial cells [nTPM]":"47.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"90.9","Single Cell Type RNA - Erythroid cells [nTPM]":"30.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"475.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"68.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.3","Single Cell Type RNA - Fibroblasts [nTPM]":"126.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"32.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"38.5","Single Cell Type RNA - granulocytes [nTPM]":"71.7","Single Cell Type RNA - Granulosa cells [nTPM]":"57.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"68.9","Single Cell Type RNA - Hepatocytes [nTPM]":"18.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"9.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"405.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.2","Single Cell Type RNA - Ionocytes [nTPM]":"50.8","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"17.5","Single Cell Type RNA - Late spermatids [nTPM]":"124.4","Single Cell Type RNA - Leydig cells [nTPM]":"63.6","Single Cell Type RNA - Macrophages [nTPM]":"12.1","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"125.5","Single Cell Type RNA - monocytes [nTPM]":"1.6","Single Cell Type RNA - Muller glia cells [nTPM]":"33.5","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"327.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"227.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"31.7","Single Cell Type RNA - Paneth cells [nTPM]":"72.5","Single Cell Type RNA - Peritubular cells [nTPM]":"103.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"41.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"40.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"57.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"37.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"30.6","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"142.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"70.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.3","Single Cell Type RNA - Spermatogonia [nTPM]":"17.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"83.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"104.7","Single Cell Type RNA - T-cells [nTPM]":"7.6","Single Cell Type RNA - Theca cells [nTPM]":"168.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"43.7","Single Cell Type RNA - Urothelial cells [nTPM]":"75.9"},{"Gene":"PDGFA","Gene synonym":["PDGF-A","PDGF1"],"Ensembl":"ENSG00000197461","Gene description":"Platelet derived growth factor subunit A","Uniprot":["P04085"],"Chromosome":"7","Position":"497258-520296","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Human disease related genes","Predicted intracellular proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Developmental protein","Growth factor","Mitogen"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"95.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"89.8","Breast myoepithelial cells":"154.9","Paneth cells":"97.0","Smooth muscle cells":"110.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"11.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"WM-115":"311.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005579","HPA065024"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"580000","Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 80: Striated muscle - Unknown function","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB005579":"AB_2161916","HPA065024":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.83e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.17e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.75e-4"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.78e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.37e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.85e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.35e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.67e-4"},"Tissue RNA - adipose tissue [nTPM]":"15.4","Tissue RNA - adrenal gland [nTPM]":"8.5","Tissue RNA - amygdala [nTPM]":"29.3","Tissue RNA - appendix [nTPM]":"7.9","Tissue RNA - basal ganglia [nTPM]":"36.8","Tissue RNA - bone marrow [nTPM]":"1.7","Tissue RNA - breast [nTPM]":"17.0","Tissue RNA - cerebellum [nTPM]":"36.6","Tissue RNA - cerebral cortex [nTPM]":"32.4","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"20.5","Tissue RNA - colon [nTPM]":"29.2","Tissue RNA - duodenum [nTPM]":"20.2","Tissue RNA - endometrium 1 [nTPM]":"26.1","Tissue RNA - epididymis [nTPM]":"11.2","Tissue RNA - esophagus [nTPM]":"9.6","Tissue RNA - fallopian tube [nTPM]":"21.2","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"21.1","Tissue RNA - hippocampal formation [nTPM]":"27.0","Tissue RNA - hypothalamus [nTPM]":"27.5","Tissue RNA - kidney [nTPM]":"22.2","Tissue RNA - liver [nTPM]":"8.5","Tissue RNA - lung [nTPM]":"24.9","Tissue RNA - lymph node [nTPM]":"3.5","Tissue RNA - medulla oblongata [nTPM]":"46.4","Tissue RNA - midbrain [nTPM]":"37.5","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"71.6","Tissue RNA - parathyroid gland [nTPM]":"6.6","Tissue RNA - pituitary gland [nTPM]":"10.2","Tissue RNA - placenta [nTPM]":"26.8","Tissue RNA - pons [nTPM]":"40.7","Tissue RNA - prostate [nTPM]":"23.3","Tissue RNA - rectum [nTPM]":"14.8","Tissue RNA - retina [nTPM]":"5.2","Tissue RNA - salivary gland [nTPM]":"20.3","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"95.2","Tissue RNA - skin 1 [nTPM]":"12.5","Tissue RNA - small intestine [nTPM]":"25.9","Tissue RNA - smooth muscle [nTPM]":"10.2","Tissue RNA - spinal cord [nTPM]":"35.8","Tissue RNA - spleen [nTPM]":"16.3","Tissue RNA - stomach 1 [nTPM]":"32.1","Tissue RNA - testis [nTPM]":"4.5","Tissue RNA - thalamus [nTPM]":"36.5","Tissue RNA - thymus [nTPM]":"6.6","Tissue RNA - thyroid gland [nTPM]":"10.0","Tissue RNA - tongue [nTPM]":"15.1","Tissue RNA - tonsil [nTPM]":"2.4","Tissue RNA - urinary bladder [nTPM]":"17.8","Tissue RNA - vagina [nTPM]":"15.9","Tissue RNA - white matter [nTPM]":"58.8","Cell RNA - A-431 [nTPM]":"22.9","Cell RNA - A549 [nTPM]":"15.3","Cell RNA - AF22 [nTPM]":"1.5","Cell RNA - AN3-CA [nTPM]":"21.6","Cell RNA - ASC diff [nTPM]":"4.1","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"50.7","Cell RNA - BJ [nTPM]":"5.0","Cell RNA - BJ hTERT+ [nTPM]":"2.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"6.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.4","Cell RNA - CACO-2 [nTPM]":"23.8","Cell RNA - CAPAN-2 [nTPM]":"25.3","Cell RNA - Daudi [nTPM]":"0.6","Cell RNA - EFO-21 [nTPM]":"8.7","Cell RNA - fHDF\/TERT166 [nTPM]":"4.3","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"56.6","Cell RNA - HAP1 [nTPM]":"1.5","Cell RNA - HBEC3-KT [nTPM]":"69.0","Cell RNA - HBF TERT88 [nTPM]":"3.4","Cell RNA - HDLM-2 [nTPM]":"12.9","Cell RNA - HEK 293 [nTPM]":"2.3","Cell RNA - HEL [nTPM]":"0.3","Cell RNA - HeLa [nTPM]":"13.3","Cell RNA - Hep G2 [nTPM]":"8.7","Cell RNA - HHSteC [nTPM]":"26.9","Cell RNA - HL-60 [nTPM]":"2.4","Cell RNA - HMC-1 [nTPM]":"2.2","Cell RNA - HSkMC [nTPM]":"3.0","Cell RNA - hTCEpi [nTPM]":"26.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"21.3","Cell RNA - hTERT-RPE1 [nTPM]":"8.5","Cell RNA - HUVEC TERT2 [nTPM]":"12.5","Cell RNA - JURKAT [nTPM]":"1.3","Cell RNA - K-562 [nTPM]":"2.3","Cell RNA - Karpas-707 [nTPM]":"3.1","Cell RNA - LHCN-M2 [nTPM]":"15.8","Cell RNA - MCF7 [nTPM]":"28.7","Cell RNA - MOLT-4 [nTPM]":"3.5","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"40.1","Cell RNA - OE19 [nTPM]":"8.9","Cell RNA - PC-3 [nTPM]":"3.3","Cell RNA - REH [nTPM]":"11.6","Cell RNA - RH-30 [nTPM]":"1.5","Cell RNA - RPMI-8226 [nTPM]":"2.5","Cell RNA - RPTEC TERT1 [nTPM]":"9.0","Cell RNA - RT4 [nTPM]":"5.3","Cell RNA - SCLC-21H [nTPM]":"2.1","Cell RNA - SH-SY5Y [nTPM]":"1.8","Cell RNA - SiHa [nTPM]":"76.5","Cell RNA - SK-BR-3 [nTPM]":"4.2","Cell RNA - SK-MEL-30 [nTPM]":"13.3","Cell RNA - SuSa [nTPM]":"47.5","Cell RNA - T-47d [nTPM]":"10.7","Cell RNA - THP-1 [nTPM]":"2.6","Cell RNA - TIME [nTPM]":"37.3","Cell RNA - U-138 MG [nTPM]":"13.6","Cell RNA - U-2 OS [nTPM]":"37.8","Cell RNA - U-2197 [nTPM]":"8.0","Cell RNA - U-251 MG [nTPM]":"31.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"1.4","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"12.3","Cell RNA - U-937 [nTPM]":"7.1","Cell RNA - WM-115 [nTPM]":"311.4","Blood RNA - basophil [nTPM]":"11.3","Blood RNA - classical monocyte [nTPM]":"1.6","Blood RNA - eosinophil [nTPM]":"2.4","Blood RNA - gdT-cell [nTPM]":"1.6","Blood RNA - intermediate monocyte [nTPM]":"1.9","Blood RNA - MAIT T-cell [nTPM]":"2.2","Blood RNA - memory B-cell [nTPM]":"1.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.6","Blood RNA - memory CD8 T-cell [nTPM]":"1.5","Blood RNA - myeloid DC [nTPM]":"1.5","Blood RNA - naive B-cell [nTPM]":"1.8","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.0","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"3.4","Blood RNA - non-classical monocyte [nTPM]":"3.3","Blood RNA - plasmacytoid DC [nTPM]":"2.1","Blood RNA - T-reg [nTPM]":"1.8","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"29.3","Brain RNA - basal ganglia [nTPM]":"36.8","Brain RNA - cerebellum [nTPM]":"36.6","Brain RNA - cerebral cortex [nTPM]":"32.4","Brain RNA - hippocampal formation [nTPM]":"27.0","Brain RNA - hypothalamus [nTPM]":"27.5","Brain RNA - medulla oblongata [nTPM]":"46.4","Brain RNA - midbrain [nTPM]":"37.5","Brain RNA - pons [nTPM]":"40.7","Brain RNA - spinal cord [nTPM]":"35.8","Brain RNA - thalamus [nTPM]":"36.5","Brain RNA - white matter [nTPM]":"58.8","Single Cell Type RNA - Adipocytes [nTPM]":"15.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"89.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"11.9","Single Cell Type RNA - Astrocytes [nTPM]":"11.1","Single Cell Type RNA - B-cells [nTPM]":"1.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"12.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"59.7","Single Cell Type RNA - Bipolar cells [nTPM]":"15.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"154.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"29.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"11.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - dendritic cells [nTPM]":"1.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"76.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"15.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"49.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"19.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"53.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.4","Single Cell Type RNA - Fibroblasts [nTPM]":"12.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.7","Single Cell Type RNA - granulocytes [nTPM]":"10.8","Single Cell Type RNA - Granulosa cells [nTPM]":"18.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"21.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.0","Single Cell Type RNA - Horizontal cells [nTPM]":"32.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"40.5","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.3","Single Cell Type RNA - Langerhans cells [nTPM]":"10.4","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"2.1","Single Cell Type RNA - Macrophages [nTPM]":"14.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.7","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"5.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"27.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"72.6","Single Cell Type RNA - Paneth cells [nTPM]":"97.0","Single Cell Type RNA - Peritubular cells [nTPM]":"6.4","Single Cell Type RNA - Plasma cells [nTPM]":"4.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"47.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"8.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"48.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"110.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"3.9","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"32.1","Single Cell Type RNA - Urothelial cells [nTPM]":"18.2"},{"Gene":"PDGFB","Gene synonym":["SIS","SSV"],"Ensembl":"ENSG00000100311","Gene description":"Platelet derived growth factor subunit B","Uniprot":["P01127"],"Chromosome":"22","Position":"39223359-39244982","Protein class":["Cancer-related genes","Candidate cardiovascular disease genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Developmental protein","Growth factor","Mitogen"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"75.0","Endothelial cells":"60.6","Langerhans cells":"44.3","Macrophages":"25.5","Pancreatic endocrine cells":"54.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"10.0"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"T-cells":"10.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"33.8","EFO-21":"69.2","HUVEC TERT2":"52.6","SK-BR-3":"53.5","TIME":"68.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011604","HPA011972","CAB018341"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":4390000,"Blood concentration - Conc. blood MS [pg\/L]":"950000","Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 38: EFO-21 - Unknown function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB011604":"AB_2162180","CAB018341":"AB_2162187","HPA011972":"AB_1855134"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.96e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.94e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.41e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.84e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.34e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.67e-5"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.68e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.12e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.47e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.50e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Tissue RNA - adipose tissue [nTPM]":"32.6","Tissue RNA - adrenal gland [nTPM]":"6.4","Tissue RNA - amygdala [nTPM]":"14.7","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"10.7","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"24.0","Tissue RNA - cerebellum [nTPM]":"10.3","Tissue RNA - cerebral cortex [nTPM]":"22.2","Tissue RNA - cervix [nTPM]":"7.5","Tissue RNA - choroid plexus [nTPM]":"4.8","Tissue RNA - colon [nTPM]":"20.6","Tissue RNA - duodenum [nTPM]":"4.9","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"6.2","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"11.7","Tissue RNA - heart muscle [nTPM]":"31.2","Tissue RNA - hippocampal formation [nTPM]":"12.0","Tissue RNA - hypothalamus [nTPM]":"9.8","Tissue RNA - kidney [nTPM]":"17.0","Tissue RNA - liver [nTPM]":"3.7","Tissue RNA - lung [nTPM]":"28.1","Tissue RNA - lymph node [nTPM]":"7.4","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"3.8","Tissue RNA - pancreas [nTPM]":"8.8","Tissue RNA - parathyroid gland [nTPM]":"8.9","Tissue RNA - pituitary gland [nTPM]":"4.0","Tissue RNA - placenta [nTPM]":"40.2","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"7.6","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"0.8","Tissue RNA - salivary gland [nTPM]":"10.6","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"18.7","Tissue RNA - skin 1 [nTPM]":"10.3","Tissue RNA - small intestine [nTPM]":"9.1","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"10.6","Tissue RNA - spleen [nTPM]":"6.6","Tissue RNA - stomach 1 [nTPM]":"7.9","Tissue RNA - testis [nTPM]":"3.4","Tissue RNA - thalamus [nTPM]":"16.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"16.1","Tissue RNA - tongue [nTPM]":"11.0","Tissue RNA - tonsil [nTPM]":"1.6","Tissue RNA - urinary bladder [nTPM]":"8.5","Tissue RNA - vagina [nTPM]":"6.6","Tissue RNA - white matter [nTPM]":"9.4","Cell RNA - A-431 [nTPM]":"33.8","Cell RNA - A549 [nTPM]":"2.6","Cell RNA - AF22 [nTPM]":"8.4","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"9.9","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"13.0","Cell RNA - CAPAN-2 [nTPM]":"10.3","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"69.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"3.1","Cell RNA - HaCaT [nTPM]":"12.4","Cell RNA - HAP1 [nTPM]":"0.5","Cell RNA - HBEC3-KT [nTPM]":"2.8","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"0.2","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"1.1","Cell RNA - Hep G2 [nTPM]":"4.8","Cell RNA - HHSteC [nTPM]":"4.3","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"18.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.4","Cell RNA - hTERT-RPE1 [nTPM]":"0.9","Cell RNA - HUVEC TERT2 [nTPM]":"52.6","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"1.3","Cell RNA - Karpas-707 [nTPM]":"6.1","Cell RNA - LHCN-M2 [nTPM]":"1.9","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"3.2","Cell RNA - OE19 [nTPM]":"8.1","Cell RNA - PC-3 [nTPM]":"3.4","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.3","Cell RNA - RPMI-8226 [nTPM]":"22.8","Cell RNA - RPTEC TERT1 [nTPM]":"27.7","Cell RNA - RT4 [nTPM]":"0.1","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.6","Cell RNA - SK-BR-3 [nTPM]":"53.5","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"6.0","Cell RNA - T-47d [nTPM]":"24.3","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"68.1","Cell RNA - U-138 MG [nTPM]":"0.1","Cell RNA - U-2 OS [nTPM]":"6.4","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"7.5","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.4","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"1.5","Cell RNA - WM-115 [nTPM]":"31.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"7.3","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"10.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"4.3","Blood RNA - memory CD8 T-cell [nTPM]":"5.6","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"3.6","Blood RNA - naive CD8 T-cell [nTPM]":"1.9","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.3","Blood RNA - T-reg [nTPM]":"2.3","Blood RNA - total PBMC [nTPM]":"2.1","Brain RNA - amygdala [nTPM]":"14.7","Brain RNA - basal ganglia [nTPM]":"10.7","Brain RNA - cerebellum [nTPM]":"10.3","Brain RNA - cerebral cortex [nTPM]":"22.2","Brain RNA - hippocampal formation [nTPM]":"12.0","Brain RNA - hypothalamus [nTPM]":"9.8","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"10.6","Brain RNA - thalamus [nTPM]":"16.0","Brain RNA - white matter [nTPM]":"9.4","Single Cell Type RNA - Adipocytes [nTPM]":"75.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"1.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - dendritic cells [nTPM]":"4.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"20.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"60.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.6","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.5","Single Cell Type RNA - Fibroblasts [nTPM]":"1.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"5.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"16.8","Single Cell Type RNA - Hepatocytes [nTPM]":"1.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"2.6","Single Cell Type RNA - Langerhans cells [nTPM]":"44.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.1","Single Cell Type RNA - Leydig cells [nTPM]":"0.6","Single Cell Type RNA - Macrophages [nTPM]":"25.5","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"1.1","Single Cell Type RNA - Muller glia cells [nTPM]":"0.3","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.5","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"1.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.6"},{"Gene":"PDGFRA","Gene synonym":["CD140a","GAS9","PDGFR2"],"Ensembl":"ENSG00000134853","Gene description":"Platelet derived growth factor receptor alpha","Uniprot":["P16234"],"Chromosome":"4","Position":"54229280-54298245","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis","Host-virus interaction"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"ovary":"190.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"8","RNA single cell type specific nTPM":{"Endometrial stromal cells":"423.9","Fibroblasts":"256.4","Leydig cells":"449.8","Oligodendrocyte precursor cells":"499.6","Peritubular cells":"408.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"glioma":"30.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"468.1","ASC TERT1":"216.1","BJ hTERT+":"279.4","fHDF\/TERT166":"195.9","HHSteC":"156.3","HSkMC":"392.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004947","CAB018143"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"300000","Blood expression cluster":"Cluster 34: Basophils - Unknown function","Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm","Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB018143":"AB_2162351","HPA004947":"AB_2732399"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.59e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.92e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.33e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.01e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.79e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.58e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-3"},"Tissue RNA - adipose tissue [nTPM]":"46.0","Tissue RNA - adrenal gland [nTPM]":"28.9","Tissue RNA - amygdala [nTPM]":"13.9","Tissue RNA - appendix [nTPM]":"40.4","Tissue RNA - basal ganglia [nTPM]":"13.7","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"40.1","Tissue RNA - cerebellum [nTPM]":"8.1","Tissue RNA - cerebral cortex [nTPM]":"12.8","Tissue RNA - cervix [nTPM]":"50.8","Tissue RNA - choroid plexus [nTPM]":"18.1","Tissue RNA - colon [nTPM]":"37.7","Tissue RNA - duodenum [nTPM]":"22.4","Tissue RNA - endometrium 1 [nTPM]":"44.3","Tissue RNA - epididymis [nTPM]":"21.8","Tissue RNA - esophagus [nTPM]":"22.5","Tissue RNA - fallopian tube [nTPM]":"50.9","Tissue RNA - gallbladder [nTPM]":"38.5","Tissue RNA - heart muscle [nTPM]":"32.1","Tissue RNA - hippocampal formation [nTPM]":"11.9","Tissue RNA - hypothalamus [nTPM]":"11.0","Tissue RNA - kidney [nTPM]":"26.5","Tissue RNA - liver [nTPM]":"16.0","Tissue RNA - lung [nTPM]":"37.9","Tissue RNA - lymph node [nTPM]":"8.5","Tissue RNA - medulla oblongata [nTPM]":"16.7","Tissue RNA - midbrain [nTPM]":"11.9","Tissue RNA - ovary [nTPM]":"190.2","Tissue RNA - pancreas [nTPM]":"13.4","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"3.7","Tissue RNA - placenta [nTPM]":"62.7","Tissue RNA - pons [nTPM]":"15.1","Tissue RNA - prostate [nTPM]":"15.0","Tissue RNA - rectum [nTPM]":"35.2","Tissue RNA - retina [nTPM]":"5.3","Tissue RNA - salivary gland [nTPM]":"16.6","Tissue RNA - seminal vesicle [nTPM]":"18.9","Tissue RNA - skeletal muscle [nTPM]":"9.6","Tissue RNA - skin 1 [nTPM]":"14.8","Tissue RNA - small intestine [nTPM]":"31.3","Tissue RNA - smooth muscle [nTPM]":"48.1","Tissue RNA - spinal cord [nTPM]":"12.1","Tissue RNA - spleen [nTPM]":"46.2","Tissue RNA - stomach 1 [nTPM]":"29.4","Tissue RNA - testis [nTPM]":"13.6","Tissue RNA - thalamus [nTPM]":"8.9","Tissue RNA - thymus [nTPM]":"7.6","Tissue RNA - thyroid gland [nTPM]":"16.5","Tissue RNA - tongue [nTPM]":"41.9","Tissue RNA - tonsil [nTPM]":"7.2","Tissue RNA - urinary bladder [nTPM]":"63.9","Tissue RNA - vagina [nTPM]":"38.0","Tissue RNA - white matter [nTPM]":"20.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"1.0","Cell RNA - AN3-CA [nTPM]":"0.8","Cell RNA - ASC diff [nTPM]":"468.1","Cell RNA - ASC TERT1 [nTPM]":"216.1","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"25.4","Cell RNA - BJ hTERT+ [nTPM]":"279.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.7","Cell RNA - CACO-2 [nTPM]":"67.6","Cell RNA - CAPAN-2 [nTPM]":"0.5","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"195.9","Cell RNA - GAMG [nTPM]":"0.8","Cell RNA - HaCaT [nTPM]":"0.6","Cell RNA - HAP1 [nTPM]":"19.6","Cell RNA - HBEC3-KT [nTPM]":"0.2","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"2.6","Cell RNA - HEK 293 [nTPM]":"1.0","Cell RNA - HEL [nTPM]":"0.7","Cell RNA - HeLa [nTPM]":"0.7","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"156.3","Cell RNA - HL-60 [nTPM]":"0.3","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"392.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"31.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"5.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"0.6","Cell RNA - Karpas-707 [nTPM]":"0.9","Cell RNA - LHCN-M2 [nTPM]":"1.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.4","Cell RNA - NB-4 [nTPM]":"1.2","Cell RNA - NTERA-2 [nTPM]":"3.5","Cell RNA - OE19 [nTPM]":"0.3","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.1","Cell RNA - RPMI-8226 [nTPM]":"0.1","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.4","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"37.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.5","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"2.0","Cell RNA - T-47d [nTPM]":"0.7","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.8","Cell RNA - U-138 MG [nTPM]":"84.9","Cell RNA - U-2 OS [nTPM]":"3.2","Cell RNA - U-2197 [nTPM]":"93.9","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.8","Cell RNA - U-87 MG [nTPM]":"2.6","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"2.2","Blood RNA - basophil [nTPM]":"0.7","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.1","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.2","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"13.9","Brain RNA - basal ganglia [nTPM]":"13.7","Brain RNA - cerebellum [nTPM]":"8.1","Brain RNA - cerebral cortex [nTPM]":"12.8","Brain RNA - hippocampal formation [nTPM]":"11.9","Brain RNA - hypothalamus [nTPM]":"11.0","Brain RNA - medulla oblongata [nTPM]":"16.7","Brain RNA - midbrain [nTPM]":"11.9","Brain RNA - pons [nTPM]":"15.1","Brain RNA - spinal cord [nTPM]":"12.1","Brain RNA - thalamus [nTPM]":"8.9","Brain RNA - white matter [nTPM]":"20.0","Single Cell Type RNA - Adipocytes [nTPM]":"11.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"5.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"4.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - dendritic cells [nTPM]":"0.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.2","Single Cell Type RNA - Early spermatids [nTPM]":"2.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"423.9","Single Cell Type RNA - Endothelial cells [nTPM]":"5.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.0","Single Cell Type RNA - Fibroblasts [nTPM]":"256.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"5.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"27.3","Single Cell Type RNA - Late spermatids [nTPM]":"17.2","Single Cell Type RNA - Leydig cells [nTPM]":"449.8","Single Cell Type RNA - Macrophages [nTPM]":"5.4","Single Cell Type RNA - Melanocytes [nTPM]":"23.2","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"4.7","Single Cell Type RNA - Muller glia cells [nTPM]":"17.5","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"499.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"408.9","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.6","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"13.9","Single Cell Type RNA - Spermatocytes [nTPM]":"1.0","Single Cell Type RNA - Spermatogonia [nTPM]":"3.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"2.5","Single Cell Type RNA - Theca cells [nTPM]":"49.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.0"},{"Gene":"PDGFRB","Gene synonym":["CD140b","JTK12","PDGFR","PDGFR1"],"Ensembl":"ENSG00000113721","Gene description":"Platelet derived growth factor receptor beta","Uniprot":["P09619"],"Chromosome":"5","Position":"150113839-150155872","Protein class":["Cancer-related genes","CD markers","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","RAS pathway related proteins"],"Biological process":["Chemotaxis"],"Molecular function":["Developmental protein","Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Sertoli cells":"1288.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"non-classical monocyte":"1.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"ASC diff":"1350.1","ASC TERT1":"462.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB003842","CAB018144","HPA028499"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"39000000","Blood expression cluster":"Cluster 14: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"CAB003842":"AB_562328","CAB018144":"AB_2162497","HPA028499":"AB_10602018"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.75e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.60e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.61e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.87e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.13e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.47e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.11e-4"},"Tissue RNA - adipose tissue [nTPM]":"171.2","Tissue RNA - adrenal gland [nTPM]":"25.1","Tissue RNA - amygdala [nTPM]":"25.4","Tissue RNA - appendix [nTPM]":"27.5","Tissue RNA - basal ganglia [nTPM]":"27.2","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"106.3","Tissue RNA - cerebellum [nTPM]":"20.5","Tissue RNA - cerebral cortex [nTPM]":"33.3","Tissue RNA - cervix [nTPM]":"155.9","Tissue RNA - choroid plexus [nTPM]":"43.5","Tissue RNA - colon [nTPM]":"41.6","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"101.1","Tissue RNA - epididymis [nTPM]":"24.2","Tissue RNA - esophagus [nTPM]":"24.1","Tissue RNA - fallopian tube [nTPM]":"89.6","Tissue RNA - gallbladder [nTPM]":"124.5","Tissue RNA - heart muscle [nTPM]":"75.7","Tissue RNA - hippocampal formation [nTPM]":"22.1","Tissue RNA - hypothalamus [nTPM]":"23.2","Tissue RNA - kidney [nTPM]":"49.7","Tissue RNA - liver [nTPM]":"13.4","Tissue RNA - lung [nTPM]":"98.3","Tissue RNA - lymph node [nTPM]":"27.5","Tissue RNA - medulla oblongata [nTPM]":"22.1","Tissue RNA - midbrain [nTPM]":"24.6","Tissue RNA - ovary [nTPM]":"105.5","Tissue RNA - pancreas [nTPM]":"20.8","Tissue RNA - parathyroid gland [nTPM]":"21.9","Tissue RNA - pituitary gland [nTPM]":"23.0","Tissue RNA - placenta [nTPM]":"113.3","Tissue RNA - pons [nTPM]":"22.8","Tissue RNA - prostate [nTPM]":"56.2","Tissue RNA - rectum [nTPM]":"14.1","Tissue RNA - retina [nTPM]":"6.3","Tissue RNA - salivary gland [nTPM]":"34.5","Tissue RNA - seminal vesicle [nTPM]":"43.3","Tissue RNA - skeletal muscle [nTPM]":"38.1","Tissue RNA - skin 1 [nTPM]":"65.0","Tissue RNA - small intestine [nTPM]":"37.9","Tissue RNA - smooth muscle [nTPM]":"68.9","Tissue RNA - spinal cord [nTPM]":"19.4","Tissue RNA - spleen [nTPM]":"41.4","Tissue RNA - stomach 1 [nTPM]":"27.9","Tissue RNA - testis [nTPM]":"18.4","Tissue RNA - thalamus [nTPM]":"27.7","Tissue RNA - thymus [nTPM]":"8.7","Tissue RNA - thyroid gland [nTPM]":"66.5","Tissue RNA - tongue [nTPM]":"44.1","Tissue RNA - tonsil [nTPM]":"13.8","Tissue RNA - urinary bladder [nTPM]":"58.3","Tissue RNA - vagina [nTPM]":"98.6","Tissue RNA - white matter [nTPM]":"21.6","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"8.3","Cell RNA - AN3-CA [nTPM]":"0.4","Cell RNA - ASC diff [nTPM]":"1350.1","Cell RNA - ASC TERT1 [nTPM]":"462.7","Cell RNA - BEWO [nTPM]":"3.0","Cell RNA - BJ [nTPM]":"48.9","Cell RNA - BJ hTERT+ [nTPM]":"202.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"33.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"56.4","Cell RNA - CACO-2 [nTPM]":"5.4","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"142.0","Cell RNA - GAMG [nTPM]":"19.0","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"0.1","Cell RNA - HBEC3-KT [nTPM]":"0.4","Cell RNA - HBF TERT88 [nTPM]":"15.8","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"3.3","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"190.7","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.4","Cell RNA - HSkMC [nTPM]":"210.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.3","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"106.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.1","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"5.5","Cell RNA - LHCN-M2 [nTPM]":"5.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.6","Cell RNA - NTERA-2 [nTPM]":"9.0","Cell RNA - OE19 [nTPM]":"0.2","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"3.7","Cell RNA - RH-30 [nTPM]":"2.5","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"24.8","Cell RNA - SiHa [nTPM]":"0.5","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"38.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.6","Cell RNA - TIME [nTPM]":"0.4","Cell RNA - U-138 MG [nTPM]":"53.7","Cell RNA - U-2 OS [nTPM]":"17.2","Cell RNA - U-2197 [nTPM]":"23.1","Cell RNA - U-251 MG [nTPM]":"2.8","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"33.4","Cell RNA - U-937 [nTPM]":"0.1","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.9","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.1","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.3","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.6","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.2","Brain RNA - amygdala [nTPM]":"25.4","Brain RNA - basal ganglia [nTPM]":"27.2","Brain RNA - cerebellum [nTPM]":"20.5","Brain RNA - cerebral cortex [nTPM]":"33.3","Brain RNA - hippocampal formation [nTPM]":"22.1","Brain RNA - hypothalamus [nTPM]":"23.2","Brain RNA - medulla oblongata [nTPM]":"22.1","Brain RNA - midbrain [nTPM]":"24.6","Brain RNA - pons [nTPM]":"22.8","Brain RNA - spinal cord [nTPM]":"19.4","Brain RNA - thalamus [nTPM]":"27.7","Brain RNA - white matter [nTPM]":"21.6","Single Cell Type RNA - Adipocytes [nTPM]":"50.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"81.9","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"24.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"6.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"17.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.6","Single Cell Type RNA - dendritic cells [nTPM]":"6.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"99.5","Single Cell Type RNA - Endothelial cells [nTPM]":"32.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.1","Single Cell Type RNA - Fibroblasts [nTPM]":"123.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"2.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"2.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"1.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"1.5","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.7","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"35.6","Single Cell Type RNA - Late spermatids [nTPM]":"10.9","Single Cell Type RNA - Leydig cells [nTPM]":"165.3","Single Cell Type RNA - Macrophages [nTPM]":"3.1","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"45.0","Single Cell Type RNA - monocytes [nTPM]":"0.7","Single Cell Type RNA - Muller glia cells [nTPM]":"50.7","Single Cell Type RNA - NK-cells [nTPM]":"23.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"3.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.1","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"203.8","Single Cell Type RNA - Plasma cells [nTPM]":"2.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.9","Single Cell Type RNA - Sertoli cells [nTPM]":"1288.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"6.6","Single Cell Type RNA - Smooth muscle cells [nTPM]":"288.3","Single Cell Type RNA - Spermatocytes [nTPM]":"1.9","Single Cell Type RNA - Spermatogonia [nTPM]":"1.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"4.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"1.1"},{"Gene":"PIK3CA","Gene synonym":["PI3K"],"Ensembl":"ENSG00000121879","Gene description":"Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha","Uniprot":["P42336"],"Chromosome":"3","Position":"179148114-179240093","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Angiogenesis","Lipid metabolism","Phagocytosis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"126.7","Inhibitory neurons":"122.0","Oligodendrocyte precursor cells":"130.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA009985","CAB017804"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling","Subcellular main location":["Cytosol"],"Subcellular additional location":["Mitochondria"],"Antibody RRID":{"CAB017804":null,"HPA009985":"AB_1079610"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.49e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.37e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.21e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.50e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.74e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.7","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"3.1","Tissue RNA - appendix [nTPM]":"8.1","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"12.4","Tissue RNA - breast [nTPM]":"8.5","Tissue RNA - cerebellum [nTPM]":"9.7","Tissue RNA - cerebral cortex [nTPM]":"8.3","Tissue RNA - cervix [nTPM]":"8.7","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"4.2","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"4.8","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"5.7","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"9.5","Tissue RNA - hippocampal formation [nTPM]":"3.7","Tissue RNA - hypothalamus [nTPM]":"3.6","Tissue RNA - kidney [nTPM]":"8.2","Tissue RNA - liver [nTPM]":"7.1","Tissue RNA - lung [nTPM]":"7.9","Tissue RNA - lymph node [nTPM]":"9.2","Tissue RNA - medulla oblongata [nTPM]":"5.1","Tissue RNA - midbrain [nTPM]":"4.2","Tissue RNA - ovary [nTPM]":"10.3","Tissue RNA - pancreas [nTPM]":"4.3","Tissue RNA - parathyroid gland [nTPM]":"11.5","Tissue RNA - pituitary gland [nTPM]":"3.4","Tissue RNA - placenta [nTPM]":"11.1","Tissue RNA - pons [nTPM]":"5.1","Tissue RNA - prostate [nTPM]":"7.3","Tissue RNA - rectum [nTPM]":"5.8","Tissue RNA - retina [nTPM]":"12.4","Tissue RNA - salivary gland [nTPM]":"4.5","Tissue RNA - seminal vesicle [nTPM]":"7.1","Tissue RNA - skeletal muscle [nTPM]":"7.1","Tissue RNA - skin 1 [nTPM]":"5.5","Tissue RNA - small intestine [nTPM]":"5.3","Tissue RNA - smooth muscle [nTPM]":"8.9","Tissue RNA - spinal cord [nTPM]":"2.3","Tissue RNA - spleen [nTPM]":"8.8","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"6.1","Tissue RNA - thalamus [nTPM]":"3.7","Tissue RNA - thymus [nTPM]":"13.7","Tissue RNA - thyroid gland [nTPM]":"7.9","Tissue RNA - tongue [nTPM]":"13.0","Tissue RNA - tonsil [nTPM]":"9.2","Tissue RNA - urinary bladder [nTPM]":"8.6","Tissue RNA - vagina [nTPM]":"5.8","Tissue RNA - white matter [nTPM]":"6.4","Cell RNA - A-431 [nTPM]":"19.9","Cell RNA - A549 [nTPM]":"6.5","Cell RNA - AF22 [nTPM]":"9.6","Cell RNA - AN3-CA [nTPM]":"9.2","Cell RNA - ASC diff [nTPM]":"22.7","Cell RNA - ASC TERT1 [nTPM]":"27.7","Cell RNA - BEWO [nTPM]":"6.5","Cell RNA - BJ [nTPM]":"10.8","Cell RNA - BJ hTERT+ [nTPM]":"16.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"16.0","Cell RNA - CACO-2 [nTPM]":"5.1","Cell RNA - CAPAN-2 [nTPM]":"13.0","Cell RNA - Daudi [nTPM]":"16.1","Cell RNA - EFO-21 [nTPM]":"21.7","Cell RNA - fHDF\/TERT166 [nTPM]":"10.8","Cell RNA - GAMG [nTPM]":"14.1","Cell RNA - HaCaT [nTPM]":"5.9","Cell RNA - HAP1 [nTPM]":"8.4","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"16.5","Cell RNA - HDLM-2 [nTPM]":"32.0","Cell RNA - HEK 293 [nTPM]":"6.2","Cell RNA - HEL [nTPM]":"22.4","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"4.4","Cell RNA - HHSteC [nTPM]":"10.7","Cell RNA - HL-60 [nTPM]":"13.1","Cell RNA - HMC-1 [nTPM]":"12.6","Cell RNA - HSkMC [nTPM]":"16.8","Cell RNA - hTCEpi [nTPM]":"10.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"12.4","Cell RNA - hTERT-HME1 [nTPM]":"15.0","Cell RNA - hTERT-RPE1 [nTPM]":"13.4","Cell RNA - HUVEC TERT2 [nTPM]":"15.8","Cell RNA - JURKAT [nTPM]":"12.9","Cell RNA - K-562 [nTPM]":"10.6","Cell RNA - Karpas-707 [nTPM]":"17.3","Cell RNA - LHCN-M2 [nTPM]":"18.9","Cell RNA - MCF7 [nTPM]":"6.9","Cell RNA - MOLT-4 [nTPM]":"10.9","Cell RNA - NB-4 [nTPM]":"8.5","Cell RNA - NTERA-2 [nTPM]":"8.0","Cell RNA - OE19 [nTPM]":"8.8","Cell RNA - PC-3 [nTPM]":"7.8","Cell RNA - REH [nTPM]":"13.9","Cell RNA - RH-30 [nTPM]":"10.0","Cell RNA - RPMI-8226 [nTPM]":"16.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.5","Cell RNA - RT4 [nTPM]":"10.0","Cell RNA - SCLC-21H [nTPM]":"5.2","Cell RNA - SH-SY5Y [nTPM]":"9.9","Cell RNA - SiHa [nTPM]":"13.1","Cell RNA - SK-BR-3 [nTPM]":"10.8","Cell RNA - SK-MEL-30 [nTPM]":"16.1","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"19.0","Cell RNA - THP-1 [nTPM]":"11.1","Cell RNA - TIME [nTPM]":"21.1","Cell RNA - U-138 MG [nTPM]":"10.4","Cell RNA - U-2 OS [nTPM]":"6.5","Cell RNA - U-2197 [nTPM]":"18.1","Cell RNA - U-251 MG [nTPM]":"13.3","Cell RNA - U-266\/70 [nTPM]":"9.3","Cell RNA - U-266\/84 [nTPM]":"13.8","Cell RNA - U-698 [nTPM]":"29.0","Cell RNA - U-87 MG [nTPM]":"11.3","Cell RNA - U-937 [nTPM]":"9.6","Cell RNA - WM-115 [nTPM]":"5.4","Blood RNA - basophil [nTPM]":"1.3","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"0.4","Blood RNA - gdT-cell [nTPM]":"1.2","Blood RNA - intermediate monocyte [nTPM]":"1.0","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"1.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"0.6","Blood RNA - myeloid DC [nTPM]":"0.8","Blood RNA - naive B-cell [nTPM]":"1.6","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.8","Blood RNA - neutrophil [nTPM]":"2.2","Blood RNA - NK-cell [nTPM]":"0.7","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"0.3","Brain RNA - amygdala [nTPM]":"3.1","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"9.7","Brain RNA - cerebral cortex [nTPM]":"8.3","Brain RNA - hippocampal formation [nTPM]":"3.7","Brain RNA - hypothalamus [nTPM]":"3.6","Brain RNA - medulla oblongata [nTPM]":"5.1","Brain RNA - midbrain [nTPM]":"4.2","Brain RNA - pons [nTPM]":"5.1","Brain RNA - spinal cord [nTPM]":"2.3","Brain RNA - thalamus [nTPM]":"3.7","Brain RNA - white matter [nTPM]":"6.4","Single Cell Type RNA - Adipocytes [nTPM]":"31.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"32.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"26.8","Single Cell Type RNA - Astrocytes [nTPM]":"60.7","Single Cell Type RNA - B-cells [nTPM]":"28.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.2","Single Cell Type RNA - Bipolar cells [nTPM]":"27.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"14.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"15.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"15.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"7.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"10.2","Single Cell Type RNA - dendritic cells [nTPM]":"17.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"8.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"10.7","Single Cell Type RNA - Early spermatids [nTPM]":"2.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"14.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.7","Single Cell Type RNA - Endothelial cells [nTPM]":"25.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"2.4","Single Cell Type RNA - Erythroid cells [nTPM]":"9.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"126.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"13.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.1","Single Cell Type RNA - Fibroblasts [nTPM]":"23.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"8.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"21.6","Single Cell Type RNA - granulocytes [nTPM]":"31.6","Single Cell Type RNA - Granulosa cells [nTPM]":"19.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"33.5","Single Cell Type RNA - Hepatocytes [nTPM]":"21.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"11.1","Single Cell Type RNA - Horizontal cells [nTPM]":"38.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"122.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"10.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"23.5","Single Cell Type RNA - Langerhans cells [nTPM]":"24.3","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"32.6","Single Cell Type RNA - Macrophages [nTPM]":"20.9","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"75.9","Single Cell Type RNA - monocytes [nTPM]":"24.5","Single Cell Type RNA - Muller glia cells [nTPM]":"17.4","Single Cell Type RNA - NK-cells [nTPM]":"18.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"130.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"84.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.9","Single Cell Type RNA - Paneth cells [nTPM]":"10.8","Single Cell Type RNA - Peritubular cells [nTPM]":"39.5","Single Cell Type RNA - Plasma cells [nTPM]":"15.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"34.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"9.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.6","Single Cell Type RNA - Spermatocytes [nTPM]":"11.8","Single Cell Type RNA - Spermatogonia [nTPM]":"10.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"14.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"19.9","Single Cell Type RNA - Theca cells [nTPM]":"19.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"9.2","Single Cell Type RNA - Urothelial cells [nTPM]":"32.0"},{"Gene":"PML","Gene synonym":["MYL","RNF71","TRIM19"],"Ensembl":"ENSG00000140464","Gene description":"PML nuclear body scaffold","Uniprot":["P29590"],"Chromosome":"15","Position":"73994673-74047827","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Apoptosis","Biological rhythms","Host-virus interaction","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Transferase"],"Disease involvement":["Cancer-related genes","Proto-oncogene","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"127.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008312","CAB010194","CAB016304"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear bodies"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Nuclear bodies"],"Subcellular additional location":null,"Antibody RRID":{"CAB010194":"AB_2166848","CAB016304":"AB_628162","HPA008312":"AB_1079643"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.24e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.76e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.53e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.30e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.54e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.29e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.67e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.27e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.17e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.02e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.99e-2"},"Tissue RNA - adipose tissue [nTPM]":"84.4","Tissue RNA - adrenal gland [nTPM]":"29.4","Tissue RNA - amygdala [nTPM]":"14.4","Tissue RNA - appendix [nTPM]":"25.6","Tissue RNA - basal ganglia [nTPM]":"13.8","Tissue RNA - bone marrow [nTPM]":"38.1","Tissue RNA - breast [nTPM]":"77.0","Tissue RNA - cerebellum [nTPM]":"11.8","Tissue RNA - cerebral cortex [nTPM]":"16.4","Tissue RNA - cervix [nTPM]":"53.7","Tissue RNA - choroid plexus [nTPM]":"11.6","Tissue RNA - colon [nTPM]":"46.7","Tissue RNA - duodenum [nTPM]":"18.4","Tissue RNA - endometrium 1 [nTPM]":"47.1","Tissue RNA - epididymis [nTPM]":"7.5","Tissue RNA - esophagus [nTPM]":"38.3","Tissue RNA - fallopian tube [nTPM]":"44.6","Tissue RNA - gallbladder [nTPM]":"21.6","Tissue RNA - heart muscle [nTPM]":"39.3","Tissue RNA - hippocampal formation [nTPM]":"13.8","Tissue RNA - hypothalamus [nTPM]":"13.1","Tissue RNA - kidney [nTPM]":"35.4","Tissue RNA - liver [nTPM]":"25.4","Tissue RNA - lung [nTPM]":"75.2","Tissue RNA - lymph node [nTPM]":"25.6","Tissue RNA - medulla oblongata [nTPM]":"18.2","Tissue RNA - midbrain [nTPM]":"13.8","Tissue RNA - ovary [nTPM]":"37.5","Tissue RNA - pancreas [nTPM]":"20.3","Tissue RNA - parathyroid gland [nTPM]":"8.3","Tissue RNA - pituitary gland [nTPM]":"26.8","Tissue RNA - placenta [nTPM]":"23.7","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"41.5","Tissue RNA - rectum [nTPM]":"8.5","Tissue RNA - retina [nTPM]":"3.9","Tissue RNA - salivary gland [nTPM]":"44.2","Tissue RNA - seminal vesicle [nTPM]":"17.2","Tissue RNA - skeletal muscle [nTPM]":"22.5","Tissue RNA - skin 1 [nTPM]":"47.4","Tissue RNA - small intestine [nTPM]":"39.0","Tissue RNA - smooth muscle [nTPM]":"19.5","Tissue RNA - spinal cord [nTPM]":"14.6","Tissue RNA - spleen [nTPM]":"48.6","Tissue RNA - stomach 1 [nTPM]":"35.3","Tissue RNA - testis [nTPM]":"11.3","Tissue RNA - thalamus [nTPM]":"15.2","Tissue RNA - thymus [nTPM]":"17.0","Tissue RNA - thyroid gland [nTPM]":"48.1","Tissue RNA - tongue [nTPM]":"7.9","Tissue RNA - tonsil [nTPM]":"15.2","Tissue RNA - urinary bladder [nTPM]":"42.7","Tissue RNA - vagina [nTPM]":"44.5","Tissue RNA - white matter [nTPM]":"13.1","Cell RNA - A-431 [nTPM]":"37.2","Cell RNA - A549 [nTPM]":"13.8","Cell RNA - AF22 [nTPM]":"11.8","Cell RNA - AN3-CA [nTPM]":"11.4","Cell RNA - ASC diff [nTPM]":"30.2","Cell RNA - ASC TERT1 [nTPM]":"43.2","Cell RNA - BEWO [nTPM]":"40.6","Cell RNA - BJ [nTPM]":"18.5","Cell RNA - BJ hTERT+ [nTPM]":"31.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"55.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"63.3","Cell RNA - CACO-2 [nTPM]":"14.6","Cell RNA - CAPAN-2 [nTPM]":"64.2","Cell RNA - Daudi [nTPM]":"16.4","Cell RNA - EFO-21 [nTPM]":"63.7","Cell RNA - fHDF\/TERT166 [nTPM]":"31.6","Cell RNA - GAMG [nTPM]":"53.3","Cell RNA - HaCaT [nTPM]":"66.6","Cell RNA - HAP1 [nTPM]":"16.3","Cell RNA - HBEC3-KT [nTPM]":"37.1","Cell RNA - HBF TERT88 [nTPM]":"7.6","Cell RNA - HDLM-2 [nTPM]":"58.0","Cell RNA - HEK 293 [nTPM]":"25.1","Cell RNA - HEL [nTPM]":"35.8","Cell RNA - HeLa [nTPM]":"21.3","Cell RNA - Hep G2 [nTPM]":"16.3","Cell RNA - HHSteC [nTPM]":"36.9","Cell RNA - HL-60 [nTPM]":"33.9","Cell RNA - HMC-1 [nTPM]":"31.1","Cell RNA - HSkMC [nTPM]":"83.7","Cell RNA - hTCEpi [nTPM]":"24.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.5","Cell RNA - hTERT-HME1 [nTPM]":"19.2","Cell RNA - hTERT-RPE1 [nTPM]":"39.3","Cell RNA - HUVEC TERT2 [nTPM]":"38.3","Cell RNA - JURKAT [nTPM]":"26.1","Cell RNA - K-562 [nTPM]":"30.6","Cell RNA - Karpas-707 [nTPM]":"28.3","Cell RNA - LHCN-M2 [nTPM]":"32.7","Cell RNA - MCF7 [nTPM]":"17.3","Cell RNA - MOLT-4 [nTPM]":"28.3","Cell RNA - NB-4 [nTPM]":"52.6","Cell RNA - NTERA-2 [nTPM]":"12.8","Cell RNA - OE19 [nTPM]":"7.7","Cell RNA - PC-3 [nTPM]":"25.0","Cell RNA - REH [nTPM]":"21.6","Cell RNA - RH-30 [nTPM]":"13.4","Cell RNA - RPMI-8226 [nTPM]":"30.8","Cell RNA - RPTEC TERT1 [nTPM]":"60.3","Cell RNA - RT4 [nTPM]":"59.5","Cell RNA - SCLC-21H [nTPM]":"10.1","Cell RNA - SH-SY5Y [nTPM]":"11.1","Cell RNA - SiHa [nTPM]":"29.7","Cell RNA - SK-BR-3 [nTPM]":"16.3","Cell RNA - SK-MEL-30 [nTPM]":"44.8","Cell RNA - SuSa [nTPM]":"10.3","Cell RNA - T-47d [nTPM]":"12.8","Cell RNA - THP-1 [nTPM]":"28.7","Cell RNA - TIME [nTPM]":"66.1","Cell RNA - U-138 MG [nTPM]":"56.6","Cell RNA - U-2 OS [nTPM]":"15.5","Cell RNA - U-2197 [nTPM]":"28.5","Cell RNA - U-251 MG [nTPM]":"38.1","Cell RNA - U-266\/70 [nTPM]":"29.4","Cell RNA - U-266\/84 [nTPM]":"20.0","Cell RNA - U-698 [nTPM]":"8.0","Cell RNA - U-87 MG [nTPM]":"38.9","Cell RNA - U-937 [nTPM]":"42.2","Cell RNA - WM-115 [nTPM]":"18.2","Blood RNA - basophil [nTPM]":"7.4","Blood RNA - classical monocyte [nTPM]":"14.7","Blood RNA - eosinophil [nTPM]":"23.4","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"20.2","Blood RNA - MAIT T-cell [nTPM]":"9.8","Blood RNA - memory B-cell [nTPM]":"12.4","Blood RNA - memory CD4 T-cell [nTPM]":"10.4","Blood RNA - memory CD8 T-cell [nTPM]":"14.1","Blood RNA - myeloid DC [nTPM]":"14.5","Blood RNA - naive B-cell [nTPM]":"10.2","Blood RNA - naive CD4 T-cell [nTPM]":"8.2","Blood RNA - naive CD8 T-cell [nTPM]":"8.5","Blood RNA - neutrophil [nTPM]":"12.0","Blood RNA - NK-cell [nTPM]":"14.5","Blood RNA - non-classical monocyte [nTPM]":"22.6","Blood RNA - plasmacytoid DC [nTPM]":"9.2","Blood RNA - T-reg [nTPM]":"14.3","Blood RNA - total PBMC [nTPM]":"10.1","Brain RNA - amygdala [nTPM]":"14.4","Brain RNA - basal ganglia [nTPM]":"13.8","Brain RNA - cerebellum [nTPM]":"11.8","Brain RNA - cerebral cortex [nTPM]":"16.4","Brain RNA - hippocampal formation [nTPM]":"13.8","Brain RNA - hypothalamus [nTPM]":"13.1","Brain RNA - medulla oblongata [nTPM]":"18.2","Brain RNA - midbrain [nTPM]":"13.8","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"14.6","Brain RNA - thalamus [nTPM]":"15.2","Brain RNA - white matter [nTPM]":"13.1","Single Cell Type RNA - Adipocytes [nTPM]":"127.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.2","Single Cell Type RNA - Astrocytes [nTPM]":"8.8","Single Cell Type RNA - B-cells [nTPM]":"24.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"30.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Bipolar cells [nTPM]":"8.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"16.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"2.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"9.4","Single Cell Type RNA - dendritic cells [nTPM]":"18.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"13.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"25.8","Single Cell Type RNA - Early spermatids [nTPM]":"3.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.7","Single Cell Type RNA - Endothelial cells [nTPM]":"48.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.3","Single Cell Type RNA - Erythroid cells [nTPM]":"29.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"19.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.0","Single Cell Type RNA - Fibroblasts [nTPM]":"20.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"58.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"26.0","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"11.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"32.2","Single Cell Type RNA - Hepatocytes [nTPM]":"11.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.8","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"14.3","Single Cell Type RNA - Ionocytes [nTPM]":"14.2","Single Cell Type RNA - Kupffer cells [nTPM]":"20.1","Single Cell Type RNA - Langerhans cells [nTPM]":"18.5","Single Cell Type RNA - Late spermatids [nTPM]":"4.0","Single Cell Type RNA - Leydig cells [nTPM]":"27.7","Single Cell Type RNA - Macrophages [nTPM]":"19.6","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"24.6","Single Cell Type RNA - Muller glia cells [nTPM]":"8.5","Single Cell Type RNA - NK-cells [nTPM]":"20.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"62.8","Single Cell Type RNA - Paneth cells [nTPM]":"15.5","Single Cell Type RNA - Peritubular cells [nTPM]":"24.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"26.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"22.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"18.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"7.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"27.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"19.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.9","Single Cell Type RNA - T-cells [nTPM]":"20.4","Single Cell Type RNA - Theca cells [nTPM]":"16.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"12.1","Single Cell Type RNA - Urothelial cells [nTPM]":"26.0"},{"Gene":"PPARG","Gene synonym":["NR1C3","PPARG1","PPARG2","PPARgamma"],"Ensembl":"ENSG00000132170","Gene description":"Peroxisome proliferator activated receptor gamma","Uniprot":["P37231"],"Chromosome":"3","Position":"12287368-12434356","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Nuclear receptors","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Biological rhythms","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adipose tissue":"165.1"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"284.1","Extravillous trophoblasts":"217.8","Granulosa cells":"232.9","Urothelial cells":"239.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"urothelial cancer":"33.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"198.7","ASC TERT1":"113.7","BEWO":"247.5","CAPAN-2":"111.6","HSkMC":"118.9","PC-3":"112.0","RT4":"157.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004282","HPA051239","HPA063663"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB004282":"AB_628115","HPA051239":"AB_2681400","HPA063663":"AB_2685081"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.27e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.27e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.41e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.32e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.38e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.59e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.68e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.52e-5"},"Tissue RNA - adipose tissue [nTPM]":"165.1","Tissue RNA - adrenal gland [nTPM]":"3.9","Tissue RNA - amygdala [nTPM]":"4.0","Tissue RNA - appendix [nTPM]":"8.7","Tissue RNA - basal ganglia [nTPM]":"3.0","Tissue RNA - bone marrow [nTPM]":"3.0","Tissue RNA - breast [nTPM]":"74.3","Tissue RNA - cerebellum [nTPM]":"3.2","Tissue RNA - cerebral cortex [nTPM]":"4.7","Tissue RNA - cervix [nTPM]":"9.7","Tissue RNA - choroid plexus [nTPM]":"0.6","Tissue RNA - colon [nTPM]":"48.7","Tissue RNA - duodenum [nTPM]":"23.6","Tissue RNA - endometrium 1 [nTPM]":"7.0","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"6.2","Tissue RNA - fallopian tube [nTPM]":"7.0","Tissue RNA - gallbladder [nTPM]":"10.5","Tissue RNA - heart muscle [nTPM]":"14.6","Tissue RNA - hippocampal formation [nTPM]":"4.0","Tissue RNA - hypothalamus [nTPM]":"2.7","Tissue RNA - kidney [nTPM]":"14.3","Tissue RNA - liver [nTPM]":"17.1","Tissue RNA - lung [nTPM]":"28.5","Tissue RNA - lymph node [nTPM]":"4.9","Tissue RNA - medulla oblongata [nTPM]":"3.7","Tissue RNA - midbrain [nTPM]":"3.5","Tissue RNA - ovary [nTPM]":"14.5","Tissue RNA - pancreas [nTPM]":"2.8","Tissue RNA - parathyroid gland [nTPM]":"7.9","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"43.6","Tissue RNA - pons [nTPM]":"3.4","Tissue RNA - prostate [nTPM]":"5.5","Tissue RNA - rectum [nTPM]":"40.6","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"5.7","Tissue RNA - seminal vesicle [nTPM]":"1.7","Tissue RNA - skeletal muscle [nTPM]":"5.2","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"15.1","Tissue RNA - smooth muscle [nTPM]":"8.7","Tissue RNA - spinal cord [nTPM]":"3.2","Tissue RNA - spleen [nTPM]":"12.0","Tissue RNA - stomach 1 [nTPM]":"35.5","Tissue RNA - testis [nTPM]":"6.9","Tissue RNA - thalamus [nTPM]":"3.5","Tissue RNA - thymus [nTPM]":"4.1","Tissue RNA - thyroid gland [nTPM]":"13.2","Tissue RNA - tongue [nTPM]":"8.1","Tissue RNA - tonsil [nTPM]":"2.1","Tissue RNA - urinary bladder [nTPM]":"67.7","Tissue RNA - vagina [nTPM]":"9.1","Tissue RNA - white matter [nTPM]":"5.0","Cell RNA - A-431 [nTPM]":"44.0","Cell RNA - A549 [nTPM]":"38.6","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"198.7","Cell RNA - ASC TERT1 [nTPM]":"113.7","Cell RNA - BEWO [nTPM]":"247.5","Cell RNA - BJ [nTPM]":"3.7","Cell RNA - BJ hTERT+ [nTPM]":"44.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"5.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"7.8","Cell RNA - CAPAN-2 [nTPM]":"111.6","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"72.9","Cell RNA - HaCaT [nTPM]":"17.3","Cell RNA - HAP1 [nTPM]":"14.4","Cell RNA - HBEC3-KT [nTPM]":"0.7","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"106.4","Cell RNA - HEK 293 [nTPM]":"20.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"8.1","Cell RNA - Hep G2 [nTPM]":"10.3","Cell RNA - HHSteC [nTPM]":"51.8","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"118.9","Cell RNA - hTCEpi [nTPM]":"9.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.8","Cell RNA - hTERT-HME1 [nTPM]":"37.5","Cell RNA - hTERT-RPE1 [nTPM]":"20.6","Cell RNA - HUVEC TERT2 [nTPM]":"0.7","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"8.3","Cell RNA - MCF7 [nTPM]":"11.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.8","Cell RNA - NTERA-2 [nTPM]":"0.7","Cell RNA - OE19 [nTPM]":"99.2","Cell RNA - PC-3 [nTPM]":"112.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"30.6","Cell RNA - RT4 [nTPM]":"157.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"1.2","Cell RNA - SiHa [nTPM]":"18.8","Cell RNA - SK-BR-3 [nTPM]":"6.7","Cell RNA - SK-MEL-30 [nTPM]":"2.2","Cell RNA - SuSa [nTPM]":"6.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"34.2","Cell RNA - TIME [nTPM]":"35.0","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"10.6","Cell RNA - U-2197 [nTPM]":"4.6","Cell RNA - U-251 MG [nTPM]":"0.2","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.1","Cell RNA - U-698 [nTPM]":"0.3","Cell RNA - U-87 MG [nTPM]":"3.2","Cell RNA - U-937 [nTPM]":"0.5","Cell RNA - WM-115 [nTPM]":"1.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.5","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.1","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"4.0","Brain RNA - basal ganglia [nTPM]":"3.0","Brain RNA - cerebellum [nTPM]":"3.2","Brain RNA - cerebral cortex [nTPM]":"4.7","Brain RNA - hippocampal formation [nTPM]":"4.0","Brain RNA - hypothalamus [nTPM]":"2.7","Brain RNA - medulla oblongata [nTPM]":"3.7","Brain RNA - midbrain [nTPM]":"3.5","Brain RNA - pons [nTPM]":"3.4","Brain RNA - spinal cord [nTPM]":"3.2","Brain RNA - thalamus [nTPM]":"3.5","Brain RNA - white matter [nTPM]":"5.0","Single Cell Type RNA - Adipocytes [nTPM]":"284.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.2","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"50.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"0.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"9.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"2.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"110.4","Single Cell Type RNA - dendritic cells [nTPM]":"1.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"93.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.1","Single Cell Type RNA - Early spermatids [nTPM]":"4.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"1.4","Single Cell Type RNA - Endothelial cells [nTPM]":"26.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"39.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"217.8","Single Cell Type RNA - Fibroblasts [nTPM]":"12.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"83.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.8","Single Cell Type RNA - granulocytes [nTPM]":"8.9","Single Cell Type RNA - Granulosa cells [nTPM]":"232.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"25.7","Single Cell Type RNA - Hepatocytes [nTPM]":"3.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"74.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"19.4","Single Cell Type RNA - Langerhans cells [nTPM]":"4.8","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"4.1","Single Cell Type RNA - Macrophages [nTPM]":"19.1","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"1.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.3","Single Cell Type RNA - Paneth cells [nTPM]":"84.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"1.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"42.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"14.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"1.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.3","Single Cell Type RNA - Spermatocytes [nTPM]":"10.9","Single Cell Type RNA - Spermatogonia [nTPM]":"22.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"88.9","Single Cell Type RNA - T-cells [nTPM]":"2.2","Single Cell Type RNA - Theca cells [nTPM]":"0.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"239.6"},{"Gene":"PRDM1","Gene synonym":["BLIMP1","PRDI-BF1"],"Ensembl":"ENSG00000057657","Gene description":"PR\/SET domain 1","Uniprot":["O75626"],"Chromosome":"6","Position":"105993463-106109939","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Adaptive immunity","Immunity","Innate immunity","Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Methyltransferase","Repressor","Transferase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"esophagus":"55.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"199.8","Langerhans cells":"199.2","Plasma cells":"786.9","T-cells":"184.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"eosinophil":"11.1","gdT-cell":"22.1","MAIT T-cell":"34.0","memory CD4 T-cell":"20.5","memory CD8 T-cell":"20.2","naive CD8 T-cell":"11.3","neutrophil":"12.5","T-reg":"29.4"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"12.5","T-cells":"34.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Karpas-707":"212.1","RPMI-8226":"42.4","U-266\/70":"81.5","U-266\/84":"57.0"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"6","RNA mouse brain regional specific nTPM":{"olfactory bulb":"3.6"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030033","HPA075427"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 84: Esophagus - Epithelial cell function","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA030033":"AB_10601050","HPA075427":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.28e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.03e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.04e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.49e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.81e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"2.1","Tissue RNA - amygdala [nTPM]":"1.6","Tissue RNA - appendix [nTPM]":"20.0","Tissue RNA - basal ganglia [nTPM]":"1.6","Tissue RNA - bone marrow [nTPM]":"20.3","Tissue RNA - breast [nTPM]":"6.8","Tissue RNA - cerebellum [nTPM]":"5.5","Tissue RNA - cerebral cortex [nTPM]":"1.8","Tissue RNA - cervix [nTPM]":"15.7","Tissue RNA - choroid plexus [nTPM]":"3.1","Tissue RNA - colon [nTPM]":"15.2","Tissue RNA - duodenum [nTPM]":"9.2","Tissue RNA - endometrium 1 [nTPM]":"17.2","Tissue RNA - epididymis [nTPM]":"1.3","Tissue RNA - esophagus [nTPM]":"55.2","Tissue RNA - fallopian tube [nTPM]":"5.5","Tissue RNA - gallbladder [nTPM]":"12.7","Tissue RNA - heart muscle [nTPM]":"1.7","Tissue RNA - hippocampal formation [nTPM]":"1.5","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"2.5","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"10.1","Tissue RNA - lymph node [nTPM]":"15.9","Tissue RNA - medulla oblongata [nTPM]":"3.2","Tissue RNA - midbrain [nTPM]":"1.8","Tissue RNA - ovary [nTPM]":"4.9","Tissue RNA - pancreas [nTPM]":"1.9","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"1.4","Tissue RNA - placenta [nTPM]":"5.1","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"3.4","Tissue RNA - rectum [nTPM]":"17.2","Tissue RNA - retina [nTPM]":"1.3","Tissue RNA - salivary gland [nTPM]":"9.3","Tissue RNA - seminal vesicle [nTPM]":"2.4","Tissue RNA - skeletal muscle [nTPM]":"4.3","Tissue RNA - skin 1 [nTPM]":"9.1","Tissue RNA - small intestine [nTPM]":"12.6","Tissue RNA - smooth muscle [nTPM]":"5.5","Tissue RNA - spinal cord [nTPM]":"2.4","Tissue RNA - spleen [nTPM]":"13.6","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"1.2","Tissue RNA - thalamus [nTPM]":"2.9","Tissue RNA - thymus [nTPM]":"4.2","Tissue RNA - thyroid gland [nTPM]":"9.0","Tissue RNA - tongue [nTPM]":"2.2","Tissue RNA - tonsil [nTPM]":"27.8","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"20.2","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"1.4","Cell RNA - A549 [nTPM]":"0.5","Cell RNA - AF22 [nTPM]":"1.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"1.6","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"7.2","Cell RNA - BJ hTERT+ [nTPM]":"23.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.7","Cell RNA - CACO-2 [nTPM]":"1.4","Cell RNA - CAPAN-2 [nTPM]":"9.2","Cell RNA - Daudi [nTPM]":"2.0","Cell RNA - EFO-21 [nTPM]":"0.4","Cell RNA - fHDF\/TERT166 [nTPM]":"13.8","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.5","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"3.6","Cell RNA - HBF TERT88 [nTPM]":"2.5","Cell RNA - HDLM-2 [nTPM]":"21.7","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.4","Cell RNA - HeLa [nTPM]":"4.9","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"3.6","Cell RNA - HL-60 [nTPM]":"0.8","Cell RNA - HMC-1 [nTPM]":"1.6","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"11.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"9.7","Cell RNA - hTERT-RPE1 [nTPM]":"0.7","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"1.0","Cell RNA - K-562 [nTPM]":"1.4","Cell RNA - Karpas-707 [nTPM]":"212.1","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"0.5","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"1.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.5","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"42.4","Cell RNA - RPTEC TERT1 [nTPM]":"2.1","Cell RNA - RT4 [nTPM]":"0.3","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.9","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"1.6","Cell RNA - T-47d [nTPM]":"1.0","Cell RNA - THP-1 [nTPM]":"2.4","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"7.2","Cell RNA - U-266\/70 [nTPM]":"81.5","Cell RNA - U-266\/84 [nTPM]":"57.0","Cell RNA - U-698 [nTPM]":"4.9","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"1.3","Cell RNA - WM-115 [nTPM]":"2.1","Blood RNA - basophil [nTPM]":"2.4","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"11.1","Blood RNA - gdT-cell [nTPM]":"22.1","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"34.0","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"20.5","Blood RNA - memory CD8 T-cell [nTPM]":"20.2","Blood RNA - myeloid DC [nTPM]":"0.5","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.8","Blood RNA - naive CD8 T-cell [nTPM]":"11.3","Blood RNA - neutrophil [nTPM]":"12.5","Blood RNA - NK-cell [nTPM]":"4.7","Blood RNA - non-classical monocyte [nTPM]":"0.3","Blood RNA - plasmacytoid DC [nTPM]":"0.4","Blood RNA - T-reg [nTPM]":"29.4","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"1.6","Brain RNA - basal ganglia [nTPM]":"1.6","Brain RNA - cerebellum [nTPM]":"5.5","Brain RNA - cerebral cortex [nTPM]":"1.8","Brain RNA - hippocampal formation [nTPM]":"1.5","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"3.2","Brain RNA - midbrain [nTPM]":"1.8","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.4","Brain RNA - thalamus [nTPM]":"2.9","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"93.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"5.1","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"42.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"3.4","Single Cell Type RNA - Bipolar cells [nTPM]":"0.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"19.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"52.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - dendritic cells [nTPM]":"199.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"129.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.3","Single Cell Type RNA - Early spermatids [nTPM]":"0.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"15.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"101.0","Single Cell Type RNA - Endothelial cells [nTPM]":"41.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.8","Single Cell Type RNA - Erythroid cells [nTPM]":"6.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"19.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.6","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"9.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"19.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.0","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"38.0","Single Cell Type RNA - Langerhans cells [nTPM]":"199.2","Single Cell Type RNA - Late spermatids [nTPM]":"0.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"64.5","Single Cell Type RNA - Melanocytes [nTPM]":"37.4","Single Cell Type RNA - Microglial cells [nTPM]":"23.4","Single Cell Type RNA - monocytes [nTPM]":"30.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"89.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"7.8","Single Cell Type RNA - Paneth cells [nTPM]":"103.7","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"786.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"5.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"30.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"2.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"43.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"41.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.7","Single Cell Type RNA - T-cells [nTPM]":"184.3","Single Cell Type RNA - Theca cells [nTPM]":"1.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.7","Single Cell Type RNA - Urothelial cells [nTPM]":"91.9"},{"Gene":"PTCH1","Gene synonym":["BCNS","NBCCS","PTCH"],"Ensembl":"ENSG00000185920","Gene description":"Patched 1","Uniprot":["Q13635"],"Chromosome":"9","Position":"95442980-95517057","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","Holoprosencephaly","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"cervix":"26.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Late spermatids":"237.5","Leydig cells":"191.0","Peritubular cells":"444.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"gdT-cell":"6.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"T-cells":"6.1"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"NTERA-2":"29.6","WM-115":"71.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB013717","HPA075072"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 36: GdT-cells - Adaptive immune response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 52: Non-specific - Transcription","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"CAB013717":null,"HPA075072":"AB_2686733"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.16e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.22e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.01e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.66e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-1"},"Tissue RNA - adipose tissue [nTPM]":"3.0","Tissue RNA - adrenal gland [nTPM]":"3.5","Tissue RNA - amygdala [nTPM]":"9.5","Tissue RNA - appendix [nTPM]":"4.0","Tissue RNA - basal ganglia [nTPM]":"11.6","Tissue RNA - bone marrow [nTPM]":"0.7","Tissue RNA - breast [nTPM]":"2.8","Tissue RNA - cerebellum [nTPM]":"24.6","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"26.7","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"11.3","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"15.6","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"2.9","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"8.1","Tissue RNA - heart muscle [nTPM]":"2.9","Tissue RNA - hippocampal formation [nTPM]":"4.7","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"2.2","Tissue RNA - lung [nTPM]":"5.5","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"16.0","Tissue RNA - midbrain [nTPM]":"12.7","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"6.4","Tissue RNA - parathyroid gland [nTPM]":"2.5","Tissue RNA - pituitary gland [nTPM]":"2.1","Tissue RNA - placenta [nTPM]":"3.8","Tissue RNA - pons [nTPM]":"8.0","Tissue RNA - prostate [nTPM]":"6.8","Tissue RNA - rectum [nTPM]":"12.3","Tissue RNA - retina [nTPM]":"8.3","Tissue RNA - salivary gland [nTPM]":"7.5","Tissue RNA - seminal vesicle [nTPM]":"4.0","Tissue RNA - skeletal muscle [nTPM]":"3.0","Tissue RNA - skin 1 [nTPM]":"3.2","Tissue RNA - small intestine [nTPM]":"11.6","Tissue RNA - smooth muscle [nTPM]":"2.4","Tissue RNA - spinal cord [nTPM]":"7.0","Tissue RNA - spleen [nTPM]":"3.3","Tissue RNA - stomach 1 [nTPM]":"12.5","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"24.0","Tissue RNA - thymus [nTPM]":"2.1","Tissue RNA - thyroid gland [nTPM]":"4.7","Tissue RNA - tongue [nTPM]":"4.8","Tissue RNA - tonsil [nTPM]":"3.0","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"2.9","Tissue RNA - white matter [nTPM]":"4.5","Cell RNA - A-431 [nTPM]":"10.1","Cell RNA - A549 [nTPM]":"4.7","Cell RNA - AF22 [nTPM]":"20.3","Cell RNA - AN3-CA [nTPM]":"12.9","Cell RNA - ASC diff [nTPM]":"3.0","Cell RNA - ASC TERT1 [nTPM]":"5.0","Cell RNA - BEWO [nTPM]":"11.4","Cell RNA - BJ [nTPM]":"1.9","Cell RNA - BJ hTERT+ [nTPM]":"1.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.4","Cell RNA - CACO-2 [nTPM]":"4.9","Cell RNA - CAPAN-2 [nTPM]":"4.8","Cell RNA - Daudi [nTPM]":"8.0","Cell RNA - EFO-21 [nTPM]":"3.3","Cell RNA - fHDF\/TERT166 [nTPM]":"3.8","Cell RNA - GAMG [nTPM]":"4.4","Cell RNA - HaCaT [nTPM]":"22.3","Cell RNA - HAP1 [nTPM]":"11.7","Cell RNA - HBEC3-KT [nTPM]":"1.6","Cell RNA - HBF TERT88 [nTPM]":"1.4","Cell RNA - HDLM-2 [nTPM]":"7.9","Cell RNA - HEK 293 [nTPM]":"7.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.8","Cell RNA - Hep G2 [nTPM]":"2.3","Cell RNA - HHSteC [nTPM]":"2.7","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"4.2","Cell RNA - HSkMC [nTPM]":"4.7","Cell RNA - hTCEpi [nTPM]":"2.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.2","Cell RNA - hTERT-HME1 [nTPM]":"1.4","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"4.2","Cell RNA - JURKAT [nTPM]":"3.5","Cell RNA - K-562 [nTPM]":"7.3","Cell RNA - Karpas-707 [nTPM]":"9.1","Cell RNA - LHCN-M2 [nTPM]":"1.0","Cell RNA - MCF7 [nTPM]":"1.9","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"3.2","Cell RNA - NTERA-2 [nTPM]":"29.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.2","Cell RNA - RPTEC TERT1 [nTPM]":"1.6","Cell RNA - RT4 [nTPM]":"1.5","Cell RNA - SCLC-21H [nTPM]":"13.8","Cell RNA - SH-SY5Y [nTPM]":"7.0","Cell RNA - SiHa [nTPM]":"7.1","Cell RNA - SK-BR-3 [nTPM]":"6.8","Cell RNA - SK-MEL-30 [nTPM]":"2.9","Cell RNA - SuSa [nTPM]":"18.8","Cell RNA - T-47d [nTPM]":"1.8","Cell RNA - THP-1 [nTPM]":"2.1","Cell RNA - TIME [nTPM]":"1.1","Cell RNA - U-138 MG [nTPM]":"2.6","Cell RNA - U-2 OS [nTPM]":"12.9","Cell RNA - U-2197 [nTPM]":"13.6","Cell RNA - U-251 MG [nTPM]":"1.5","Cell RNA - U-266\/70 [nTPM]":"18.0","Cell RNA - U-266\/84 [nTPM]":"16.8","Cell RNA - U-698 [nTPM]":"5.3","Cell RNA - U-87 MG [nTPM]":"3.8","Cell RNA - U-937 [nTPM]":"3.9","Cell RNA - WM-115 [nTPM]":"71.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"6.1","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.1","Blood RNA - memory CD8 T-cell [nTPM]":"2.5","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.2","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"1.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"9.5","Brain RNA - basal ganglia [nTPM]":"11.6","Brain RNA - cerebellum [nTPM]":"24.6","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"4.7","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"16.0","Brain RNA - midbrain [nTPM]":"12.7","Brain RNA - pons [nTPM]":"8.0","Brain RNA - spinal cord [nTPM]":"7.0","Brain RNA - thalamus [nTPM]":"24.0","Brain RNA - white matter [nTPM]":"4.5","Single Cell Type RNA - Adipocytes [nTPM]":"6.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"49.0","Single Cell Type RNA - B-cells [nTPM]":"3.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"4.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"20.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"4.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"2.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"3.0","Single Cell Type RNA - dendritic cells [nTPM]":"11.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"2.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.5","Single Cell Type RNA - Early spermatids [nTPM]":"88.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"89.8","Single Cell Type RNA - Endothelial cells [nTPM]":"5.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"21.7","Single Cell Type RNA - Erythroid cells [nTPM]":"0.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"4.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.9","Single Cell Type RNA - Fibroblasts [nTPM]":"27.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"11.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"2.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"2.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"20.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"10.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.0","Single Cell Type RNA - Ionocytes [nTPM]":"4.1","Single Cell Type RNA - Kupffer cells [nTPM]":"0.9","Single Cell Type RNA - Langerhans cells [nTPM]":"1.2","Single Cell Type RNA - Late spermatids [nTPM]":"237.5","Single Cell Type RNA - Leydig cells [nTPM]":"191.0","Single Cell Type RNA - Macrophages [nTPM]":"1.4","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"55.6","Single Cell Type RNA - NK-cells [nTPM]":"54.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"39.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"20.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"2.4","Single Cell Type RNA - Paneth cells [nTPM]":"3.1","Single Cell Type RNA - Peritubular cells [nTPM]":"444.5","Single Cell Type RNA - Plasma cells [nTPM]":"3.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"4.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.4","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"4.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.4","Single Cell Type RNA - Spermatocytes [nTPM]":"4.4","Single Cell Type RNA - Spermatogonia [nTPM]":"35.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"4.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.4","Single Cell Type RNA - T-cells [nTPM]":"6.5","Single Cell Type RNA - Theca cells [nTPM]":"71.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.4"},{"Gene":"PTEN","Gene synonym":["BZS","MHAM","MMAC1","PTEN1","TEP1"],"Ensembl":"ENSG00000171862","Gene description":"Phosphatase and tensin homolog","Uniprot":["P60484"],"Chromosome":"10","Position":"87863625-87971930","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Lipid metabolism","Neurogenesis"],"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Autism spectrum disorder","Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"60.5"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004076","HPA031335"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004076":"AB_390810","HPA031335":"AB_2797221"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.72e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.45e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.43e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.50e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.08e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.35e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.54e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.41e-1"},"Tissue RNA - adipose tissue [nTPM]":"64.0","Tissue RNA - adrenal gland [nTPM]":"25.4","Tissue RNA - amygdala [nTPM]":"17.8","Tissue RNA - appendix [nTPM]":"18.6","Tissue RNA - basal ganglia [nTPM]":"19.3","Tissue RNA - bone marrow [nTPM]":"12.9","Tissue RNA - breast [nTPM]":"47.6","Tissue RNA - cerebellum [nTPM]":"34.5","Tissue RNA - cerebral cortex [nTPM]":"23.4","Tissue RNA - cervix [nTPM]":"54.8","Tissue RNA - choroid plexus [nTPM]":"15.6","Tissue RNA - colon [nTPM]":"28.1","Tissue RNA - duodenum [nTPM]":"12.9","Tissue RNA - endometrium 1 [nTPM]":"27.4","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"28.3","Tissue RNA - fallopian tube [nTPM]":"35.2","Tissue RNA - gallbladder [nTPM]":"15.6","Tissue RNA - heart muscle [nTPM]":"29.7","Tissue RNA - hippocampal formation [nTPM]":"20.4","Tissue RNA - hypothalamus [nTPM]":"18.4","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"39.2","Tissue RNA - lung [nTPM]":"39.5","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"16.6","Tissue RNA - midbrain [nTPM]":"17.8","Tissue RNA - ovary [nTPM]":"28.0","Tissue RNA - pancreas [nTPM]":"33.2","Tissue RNA - parathyroid gland [nTPM]":"11.9","Tissue RNA - pituitary gland [nTPM]":"17.3","Tissue RNA - placenta [nTPM]":"30.5","Tissue RNA - pons [nTPM]":"16.4","Tissue RNA - prostate [nTPM]":"26.3","Tissue RNA - rectum [nTPM]":"14.6","Tissue RNA - retina [nTPM]":"30.0","Tissue RNA - salivary gland [nTPM]":"19.6","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"23.7","Tissue RNA - skin 1 [nTPM]":"25.9","Tissue RNA - small intestine [nTPM]":"24.5","Tissue RNA - smooth muscle [nTPM]":"22.2","Tissue RNA - spinal cord [nTPM]":"14.5","Tissue RNA - spleen [nTPM]":"40.0","Tissue RNA - stomach 1 [nTPM]":"25.6","Tissue RNA - testis [nTPM]":"28.2","Tissue RNA - thalamus [nTPM]":"19.7","Tissue RNA - thymus [nTPM]":"31.8","Tissue RNA - thyroid gland [nTPM]":"26.1","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"16.5","Tissue RNA - urinary bladder [nTPM]":"28.1","Tissue RNA - vagina [nTPM]":"38.4","Tissue RNA - white matter [nTPM]":"17.6","Cell RNA - A-431 [nTPM]":"23.5","Cell RNA - A549 [nTPM]":"10.8","Cell RNA - AF22 [nTPM]":"12.3","Cell RNA - AN3-CA [nTPM]":"11.2","Cell RNA - ASC diff [nTPM]":"28.5","Cell RNA - ASC TERT1 [nTPM]":"19.7","Cell RNA - BEWO [nTPM]":"10.9","Cell RNA - BJ [nTPM]":"12.5","Cell RNA - BJ hTERT+ [nTPM]":"28.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"14.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"20.4","Cell RNA - CACO-2 [nTPM]":"10.9","Cell RNA - CAPAN-2 [nTPM]":"28.0","Cell RNA - Daudi [nTPM]":"28.1","Cell RNA - EFO-21 [nTPM]":"8.0","Cell RNA - fHDF\/TERT166 [nTPM]":"20.9","Cell RNA - GAMG [nTPM]":"8.3","Cell RNA - HaCaT [nTPM]":"14.1","Cell RNA - HAP1 [nTPM]":"16.6","Cell RNA - HBEC3-KT [nTPM]":"14.3","Cell RNA - HBF TERT88 [nTPM]":"22.8","Cell RNA - HDLM-2 [nTPM]":"14.1","Cell RNA - HEK 293 [nTPM]":"4.7","Cell RNA - HEL [nTPM]":"9.3","Cell RNA - HeLa [nTPM]":"28.5","Cell RNA - Hep G2 [nTPM]":"13.8","Cell RNA - HHSteC [nTPM]":"30.1","Cell RNA - HL-60 [nTPM]":"31.9","Cell RNA - HMC-1 [nTPM]":"15.3","Cell RNA - HSkMC [nTPM]":"13.5","Cell RNA - hTCEpi [nTPM]":"38.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"18.0","Cell RNA - hTERT-HME1 [nTPM]":"23.7","Cell RNA - hTERT-RPE1 [nTPM]":"60.3","Cell RNA - HUVEC TERT2 [nTPM]":"20.8","Cell RNA - JURKAT [nTPM]":"17.7","Cell RNA - K-562 [nTPM]":"7.0","Cell RNA - Karpas-707 [nTPM]":"72.6","Cell RNA - LHCN-M2 [nTPM]":"13.5","Cell RNA - MCF7 [nTPM]":"18.1","Cell RNA - MOLT-4 [nTPM]":"17.8","Cell RNA - NB-4 [nTPM]":"56.3","Cell RNA - NTERA-2 [nTPM]":"4.6","Cell RNA - OE19 [nTPM]":"19.9","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"27.6","Cell RNA - RH-30 [nTPM]":"6.4","Cell RNA - RPMI-8226 [nTPM]":"20.8","Cell RNA - RPTEC TERT1 [nTPM]":"22.9","Cell RNA - RT4 [nTPM]":"13.4","Cell RNA - SCLC-21H [nTPM]":"4.5","Cell RNA - SH-SY5Y [nTPM]":"19.9","Cell RNA - SiHa [nTPM]":"16.6","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"23.0","Cell RNA - SuSa [nTPM]":"9.7","Cell RNA - T-47d [nTPM]":"21.9","Cell RNA - THP-1 [nTPM]":"45.2","Cell RNA - TIME [nTPM]":"17.9","Cell RNA - U-138 MG [nTPM]":"44.6","Cell RNA - U-2 OS [nTPM]":"10.8","Cell RNA - U-2197 [nTPM]":"18.3","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"23.9","Cell RNA - U-266\/84 [nTPM]":"32.9","Cell RNA - U-698 [nTPM]":"30.7","Cell RNA - U-87 MG [nTPM]":"14.6","Cell RNA - U-937 [nTPM]":"29.2","Cell RNA - WM-115 [nTPM]":"2.9","Blood RNA - basophil [nTPM]":"21.3","Blood RNA - classical monocyte [nTPM]":"14.2","Blood RNA - eosinophil [nTPM]":"25.8","Blood RNA - gdT-cell [nTPM]":"6.8","Blood RNA - intermediate monocyte [nTPM]":"21.8","Blood RNA - MAIT T-cell [nTPM]":"7.2","Blood RNA - memory B-cell [nTPM]":"7.9","Blood RNA - memory CD4 T-cell [nTPM]":"7.2","Blood RNA - memory CD8 T-cell [nTPM]":"6.6","Blood RNA - myeloid DC [nTPM]":"10.3","Blood RNA - naive B-cell [nTPM]":"6.8","Blood RNA - naive CD4 T-cell [nTPM]":"8.3","Blood RNA - naive CD8 T-cell [nTPM]":"8.3","Blood RNA - neutrophil [nTPM]":"60.5","Blood RNA - NK-cell [nTPM]":"8.9","Blood RNA - non-classical monocyte [nTPM]":"15.6","Blood RNA - plasmacytoid DC [nTPM]":"8.2","Blood RNA - T-reg [nTPM]":"7.0","Blood RNA - total PBMC [nTPM]":"4.5","Brain RNA - amygdala [nTPM]":"17.8","Brain RNA - basal ganglia [nTPM]":"19.3","Brain RNA - cerebellum [nTPM]":"34.5","Brain RNA - cerebral cortex [nTPM]":"23.4","Brain RNA - hippocampal formation [nTPM]":"20.4","Brain RNA - hypothalamus [nTPM]":"18.4","Brain RNA - medulla oblongata [nTPM]":"16.6","Brain RNA - midbrain [nTPM]":"17.8","Brain RNA - pons [nTPM]":"16.4","Brain RNA - spinal cord [nTPM]":"14.5","Brain RNA - thalamus [nTPM]":"19.7","Brain RNA - white matter [nTPM]":"17.6","Single Cell Type RNA - Adipocytes [nTPM]":"67.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"35.3","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"63.3","Single Cell Type RNA - Astrocytes [nTPM]":"83.6","Single Cell Type RNA - B-cells [nTPM]":"48.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"56.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"57.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"31.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"47.3","Single Cell Type RNA - Bipolar cells [nTPM]":"113.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"49.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"41.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"46.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"57.2","Single Cell Type RNA - Club cells [nTPM]":"31.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"29.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"39.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.8","Single Cell Type RNA - dendritic cells [nTPM]":"64.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"57.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"24.7","Single Cell Type RNA - Early spermatids [nTPM]":"70.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"114.5","Single Cell Type RNA - Endothelial cells [nTPM]":"56.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"31.2","Single Cell Type RNA - Erythroid cells [nTPM]":"52.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"141.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"30.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.2","Single Cell Type RNA - Fibroblasts [nTPM]":"79.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.6","Single Cell Type RNA - granulocytes [nTPM]":"25.4","Single Cell Type RNA - Granulosa cells [nTPM]":"39.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"64.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"35.0","Single Cell Type RNA - Horizontal cells [nTPM]":"45.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"132.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"44.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"206.1","Single Cell Type RNA - Langerhans cells [nTPM]":"97.2","Single Cell Type RNA - Late spermatids [nTPM]":"92.1","Single Cell Type RNA - Leydig cells [nTPM]":"56.8","Single Cell Type RNA - Macrophages [nTPM]":"105.2","Single Cell Type RNA - Melanocytes [nTPM]":"62.2","Single Cell Type RNA - Microglial cells [nTPM]":"196.8","Single Cell Type RNA - monocytes [nTPM]":"101.5","Single Cell Type RNA - Muller glia cells [nTPM]":"61.6","Single Cell Type RNA - NK-cells [nTPM]":"44.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"139.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"95.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.6","Single Cell Type RNA - Paneth cells [nTPM]":"39.7","Single Cell Type RNA - Peritubular cells [nTPM]":"54.5","Single Cell Type RNA - Plasma cells [nTPM]":"39.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"45.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"50.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"38.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"31.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"61.2","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"66.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"170.7","Single Cell Type RNA - Spermatocytes [nTPM]":"33.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"45.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"60.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"57.3","Single Cell Type RNA - T-cells [nTPM]":"46.3","Single Cell Type RNA - Theca cells [nTPM]":"44.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"46.1","Single Cell Type RNA - Urothelial cells [nTPM]":"64.0"},{"Gene":"PTGES2","Gene synonym":["C9orf15","FLJ14038"],"Ensembl":"ENSG00000148334","Gene description":"Prostaglandin E synthase 2","Uniprot":["Q9H7Z7"],"Chromosome":"9","Position":"128120693-128128462","Protein class":["Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Prostaglandin biosynthesis","Prostaglandin metabolism"],"Molecular function":["Isomerase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Cardiomyocytes":"700.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA020631","HPA020733"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 39: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA020631":"AB_1855887","HPA020733":"AB_2670508"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.13e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.56e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.81e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.33e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"5.83e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Tissue RNA - adipose tissue [nTPM]":"18.1","Tissue RNA - adrenal gland [nTPM]":"49.8","Tissue RNA - amygdala [nTPM]":"31.6","Tissue RNA - appendix [nTPM]":"15.6","Tissue RNA - basal ganglia [nTPM]":"33.9","Tissue RNA - bone marrow [nTPM]":"6.5","Tissue RNA - breast [nTPM]":"16.0","Tissue RNA - cerebellum [nTPM]":"29.1","Tissue RNA - cerebral cortex [nTPM]":"45.8","Tissue RNA - cervix [nTPM]":"18.1","Tissue RNA - choroid plexus [nTPM]":"32.4","Tissue RNA - colon [nTPM]":"30.6","Tissue RNA - duodenum [nTPM]":"27.5","Tissue RNA - endometrium 1 [nTPM]":"21.6","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"35.3","Tissue RNA - fallopian tube [nTPM]":"17.6","Tissue RNA - gallbladder [nTPM]":"11.4","Tissue RNA - heart muscle [nTPM]":"95.0","Tissue RNA - hippocampal formation [nTPM]":"35.6","Tissue RNA - hypothalamus [nTPM]":"33.0","Tissue RNA - kidney [nTPM]":"36.4","Tissue RNA - liver [nTPM]":"37.7","Tissue RNA - lung [nTPM]":"14.8","Tissue RNA - lymph node [nTPM]":"17.6","Tissue RNA - medulla oblongata [nTPM]":"31.5","Tissue RNA - midbrain [nTPM]":"31.5","Tissue RNA - ovary [nTPM]":"16.1","Tissue RNA - pancreas [nTPM]":"37.6","Tissue RNA - parathyroid gland [nTPM]":"35.2","Tissue RNA - pituitary gland [nTPM]":"41.4","Tissue RNA - placenta [nTPM]":"9.7","Tissue RNA - pons [nTPM]":"32.1","Tissue RNA - prostate [nTPM]":"24.6","Tissue RNA - rectum [nTPM]":"9.2","Tissue RNA - retina [nTPM]":"10.0","Tissue RNA - salivary gland [nTPM]":"26.1","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"117.9","Tissue RNA - skin 1 [nTPM]":"20.9","Tissue RNA - small intestine [nTPM]":"23.8","Tissue RNA - smooth muscle [nTPM]":"7.5","Tissue RNA - spinal cord [nTPM]":"27.3","Tissue RNA - spleen [nTPM]":"21.1","Tissue RNA - stomach 1 [nTPM]":"29.6","Tissue RNA - testis [nTPM]":"14.5","Tissue RNA - thalamus [nTPM]":"31.5","Tissue RNA - thymus [nTPM]":"11.9","Tissue RNA - thyroid gland [nTPM]":"23.5","Tissue RNA - tongue [nTPM]":"78.7","Tissue RNA - tonsil [nTPM]":"9.7","Tissue RNA - urinary bladder [nTPM]":"22.3","Tissue RNA - vagina [nTPM]":"22.0","Tissue RNA - white matter [nTPM]":"31.7","Cell RNA - A-431 [nTPM]":"46.1","Cell RNA - A549 [nTPM]":"114.0","Cell RNA - AF22 [nTPM]":"15.5","Cell RNA - AN3-CA [nTPM]":"54.4","Cell RNA - ASC diff [nTPM]":"13.5","Cell RNA - ASC TERT1 [nTPM]":"12.8","Cell RNA - BEWO [nTPM]":"47.9","Cell RNA - BJ [nTPM]":"30.7","Cell RNA - BJ hTERT+ [nTPM]":"20.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"48.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.9","Cell RNA - CACO-2 [nTPM]":"86.9","Cell RNA - CAPAN-2 [nTPM]":"75.6","Cell RNA - Daudi [nTPM]":"43.5","Cell RNA - EFO-21 [nTPM]":"45.7","Cell RNA - fHDF\/TERT166 [nTPM]":"15.9","Cell RNA - GAMG [nTPM]":"36.9","Cell RNA - HaCaT [nTPM]":"108.8","Cell RNA - HAP1 [nTPM]":"22.5","Cell RNA - HBEC3-KT [nTPM]":"47.1","Cell RNA - HBF TERT88 [nTPM]":"6.5","Cell RNA - HDLM-2 [nTPM]":"28.3","Cell RNA - HEK 293 [nTPM]":"62.3","Cell RNA - HEL [nTPM]":"21.0","Cell RNA - HeLa [nTPM]":"92.7","Cell RNA - Hep G2 [nTPM]":"79.5","Cell RNA - HHSteC [nTPM]":"41.0","Cell RNA - HL-60 [nTPM]":"42.1","Cell RNA - HMC-1 [nTPM]":"39.5","Cell RNA - HSkMC [nTPM]":"18.6","Cell RNA - hTCEpi [nTPM]":"32.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"39.5","Cell RNA - hTERT-HME1 [nTPM]":"26.9","Cell RNA - hTERT-RPE1 [nTPM]":"14.2","Cell RNA - HUVEC TERT2 [nTPM]":"31.6","Cell RNA - JURKAT [nTPM]":"47.8","Cell RNA - K-562 [nTPM]":"50.2","Cell RNA - Karpas-707 [nTPM]":"26.4","Cell RNA - LHCN-M2 [nTPM]":"16.7","Cell RNA - MCF7 [nTPM]":"130.0","Cell RNA - MOLT-4 [nTPM]":"56.9","Cell RNA - NB-4 [nTPM]":"75.6","Cell RNA - NTERA-2 [nTPM]":"42.7","Cell RNA - OE19 [nTPM]":"58.7","Cell RNA - PC-3 [nTPM]":"113.9","Cell RNA - REH [nTPM]":"39.6","Cell RNA - RH-30 [nTPM]":"26.5","Cell RNA - RPMI-8226 [nTPM]":"111.6","Cell RNA - RPTEC TERT1 [nTPM]":"32.8","Cell RNA - RT4 [nTPM]":"33.1","Cell RNA - SCLC-21H [nTPM]":"69.1","Cell RNA - SH-SY5Y [nTPM]":"45.6","Cell RNA - SiHa [nTPM]":"47.3","Cell RNA - SK-BR-3 [nTPM]":"86.3","Cell RNA - SK-MEL-30 [nTPM]":"34.2","Cell RNA - SuSa [nTPM]":"6.7","Cell RNA - T-47d [nTPM]":"78.7","Cell RNA - THP-1 [nTPM]":"23.5","Cell RNA - TIME [nTPM]":"34.0","Cell RNA - U-138 MG [nTPM]":"46.3","Cell RNA - U-2 OS [nTPM]":"50.2","Cell RNA - U-2197 [nTPM]":"62.8","Cell RNA - U-251 MG [nTPM]":"63.1","Cell RNA - U-266\/70 [nTPM]":"48.9","Cell RNA - U-266\/84 [nTPM]":"25.5","Cell RNA - U-698 [nTPM]":"38.3","Cell RNA - U-87 MG [nTPM]":"39.1","Cell RNA - U-937 [nTPM]":"33.2","Cell RNA - WM-115 [nTPM]":"44.5","Blood RNA - basophil [nTPM]":"1.4","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"0.7","Blood RNA - gdT-cell [nTPM]":"3.1","Blood RNA - intermediate monocyte [nTPM]":"3.7","Blood RNA - MAIT T-cell [nTPM]":"3.8","Blood RNA - memory B-cell [nTPM]":"3.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"4.3","Blood RNA - naive B-cell [nTPM]":"2.7","Blood RNA - naive CD4 T-cell [nTPM]":"2.4","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"0.6","Blood RNA - NK-cell [nTPM]":"2.7","Blood RNA - non-classical monocyte [nTPM]":"1.8","Blood RNA - plasmacytoid DC [nTPM]":"5.8","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"1.9","Brain RNA - amygdala [nTPM]":"31.6","Brain RNA - basal ganglia [nTPM]":"33.9","Brain RNA - cerebellum [nTPM]":"29.1","Brain RNA - cerebral cortex [nTPM]":"45.8","Brain RNA - hippocampal formation [nTPM]":"35.6","Brain RNA - hypothalamus [nTPM]":"33.0","Brain RNA - medulla oblongata [nTPM]":"31.5","Brain RNA - midbrain [nTPM]":"31.5","Brain RNA - pons [nTPM]":"32.1","Brain RNA - spinal cord [nTPM]":"27.3","Brain RNA - thalamus [nTPM]":"31.5","Brain RNA - white matter [nTPM]":"31.7","Single Cell Type RNA - Adipocytes [nTPM]":"18.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"6.4","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"32.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"22.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"38.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"32.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"25.0","Single Cell Type RNA - Bipolar cells [nTPM]":"37.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"34.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"36.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"700.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"51.5","Single Cell Type RNA - Club cells [nTPM]":"25.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"82.1","Single Cell Type RNA - dendritic cells [nTPM]":"30.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"86.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"146.8","Single Cell Type RNA - Ductal cells [nTPM]":"74.6","Single Cell Type RNA - Early spermatids [nTPM]":"2.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.9","Single Cell Type RNA - Endothelial cells [nTPM]":"29.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"45.1","Single Cell Type RNA - Erythroid cells [nTPM]":"13.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"51.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"62.1","Single Cell Type RNA - Fibroblasts [nTPM]":"32.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.3","Single Cell Type RNA - granulocytes [nTPM]":"14.7","Single Cell Type RNA - Granulosa cells [nTPM]":"31.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.9","Single Cell Type RNA - Hepatocytes [nTPM]":"37.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"57.6","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"62.2","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"25.3","Single Cell Type RNA - Langerhans cells [nTPM]":"43.6","Single Cell Type RNA - Late spermatids [nTPM]":"4.8","Single Cell Type RNA - Leydig cells [nTPM]":"30.7","Single Cell Type RNA - Macrophages [nTPM]":"30.8","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"105.7","Single Cell Type RNA - Muller glia cells [nTPM]":"21.9","Single Cell Type RNA - NK-cells [nTPM]":"38.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"57.6","Single Cell Type RNA - Paneth cells [nTPM]":"60.4","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"45.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"68.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"93.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"99.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"44.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"37.2","Single Cell Type RNA - Spermatocytes [nTPM]":"3.6","Single Cell Type RNA - Spermatogonia [nTPM]":"45.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"48.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"66.6","Single Cell Type RNA - T-cells [nTPM]":"25.6","Single Cell Type RNA - Theca cells [nTPM]":"84.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"105.5","Single Cell Type RNA - Urothelial cells [nTPM]":"52.9"},{"Gene":"PTGS2","Gene synonym":["COX2"],"Ensembl":"ENSG00000073756","Gene description":"Prostaglandin-endoperoxide synthase 2","Uniprot":["P35354"],"Chromosome":"1","Position":"186671791-186680922","Protein class":["Cancer-related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Fatty acid biosynthesis","Fatty acid metabolism","Lipid biosynthesis","Lipid metabolism","Prostaglandin biosynthesis","Prostaglandin metabolism"],"Molecular function":["Dioxygenase","Oxidoreductase","Peroxidase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"116.7","seminal vesicle":"127.4","urinary bladder":"162.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Alveolar cells type 1":"342.9","Fibroblasts":"270.7","granulocytes":"347.6","Langerhans cells":"305.6","Macrophages":"173.1","Urothelial cells":"151.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"16","RNA blood cell specific nTPM":{"neutrophil":"11.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"16","RNA blood lineage specific nTPM":{"granulocytes":"11.7"},"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"BJ hTERT+":"405.5"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"hippocampal formation":"15.1"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000113","HPA001335"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Vesicles"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 50: Neutrophils - Cellular senescence","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Endoplasmic reticulum","Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB000113":null,"HPA001335":"AB_1079712"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.97e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.97e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.96e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.50e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.03e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.24e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.07e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.79e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.04e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.89e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.74e-2"},"Tissue RNA - adipose tissue [nTPM]":"17.0","Tissue RNA - adrenal gland [nTPM]":"7.9","Tissue RNA - amygdala [nTPM]":"1.4","Tissue RNA - appendix [nTPM]":"13.9","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"116.7","Tissue RNA - breast [nTPM]":"3.0","Tissue RNA - cerebellum [nTPM]":"1.1","Tissue RNA - cerebral cortex [nTPM]":"4.1","Tissue RNA - cervix [nTPM]":"62.2","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"2.6","Tissue RNA - endometrium 1 [nTPM]":"8.9","Tissue RNA - epididymis [nTPM]":"0.7","Tissue RNA - esophagus [nTPM]":"6.9","Tissue RNA - fallopian tube [nTPM]":"5.1","Tissue RNA - gallbladder [nTPM]":"31.6","Tissue RNA - heart muscle [nTPM]":"11.7","Tissue RNA - hippocampal formation [nTPM]":"1.9","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"10.2","Tissue RNA - liver [nTPM]":"8.0","Tissue RNA - lung [nTPM]":"34.3","Tissue RNA - lymph node [nTPM]":"8.9","Tissue RNA - medulla oblongata [nTPM]":"2.0","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"2.6","Tissue RNA - pancreas [nTPM]":"2.2","Tissue RNA - parathyroid gland [nTPM]":"5.6","Tissue RNA - pituitary gland [nTPM]":"3.1","Tissue RNA - placenta [nTPM]":"8.4","Tissue RNA - pons [nTPM]":"1.5","Tissue RNA - prostate [nTPM]":"25.0","Tissue RNA - rectum [nTPM]":"9.9","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"1.2","Tissue RNA - seminal vesicle [nTPM]":"127.4","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"1.6","Tissue RNA - small intestine [nTPM]":"3.6","Tissue RNA - smooth muscle [nTPM]":"12.2","Tissue RNA - spinal cord [nTPM]":"1.9","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"14.8","Tissue RNA - testis [nTPM]":"0.2","Tissue RNA - thalamus [nTPM]":"1.8","Tissue RNA - thymus [nTPM]":"5.2","Tissue RNA - thyroid gland [nTPM]":"3.2","Tissue RNA - tongue [nTPM]":"6.5","Tissue RNA - tonsil [nTPM]":"0.6","Tissue RNA - urinary bladder [nTPM]":"162.5","Tissue RNA - vagina [nTPM]":"2.2","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"21.8","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"2.5","Cell RNA - ASC TERT1 [nTPM]":"2.1","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"93.4","Cell RNA - BJ hTERT+ [nTPM]":"405.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"3.6","Cell RNA - CACO-2 [nTPM]":"15.0","Cell RNA - CAPAN-2 [nTPM]":"17.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.1","Cell RNA - GAMG [nTPM]":"2.5","Cell RNA - HaCaT [nTPM]":"12.2","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"7.6","Cell RNA - HBF TERT88 [nTPM]":"1.3","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.8","Cell RNA - HeLa [nTPM]":"2.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"13.2","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.2","Cell RNA - HSkMC [nTPM]":"0.8","Cell RNA - hTCEpi [nTPM]":"2.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"11.3","Cell RNA - hTERT-HME1 [nTPM]":"28.7","Cell RNA - hTERT-RPE1 [nTPM]":"1.0","Cell RNA - HUVEC TERT2 [nTPM]":"4.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"3.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"5.5","Cell RNA - SCLC-21H [nTPM]":"1.5","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"1.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"2.7","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"1.5","Cell RNA - U-138 MG [nTPM]":"19.3","Cell RNA - U-2 OS [nTPM]":"0.6","Cell RNA - U-2197 [nTPM]":"13.5","Cell RNA - U-251 MG [nTPM]":"0.6","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"27.7","Cell RNA - U-937 [nTPM]":"0.4","Cell RNA - WM-115 [nTPM]":"2.3","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.3","Blood RNA - eosinophil [nTPM]":"0.2","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.7","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.4","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"11.7","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.4","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"1.1","Brain RNA - cerebral cortex [nTPM]":"4.1","Brain RNA - hippocampal formation [nTPM]":"1.9","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"2.0","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"1.5","Brain RNA - spinal cord [nTPM]":"1.9","Brain RNA - thalamus [nTPM]":"1.8","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"5.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"342.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"77.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"7.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"118.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"59.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"72.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"79.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"4.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"50.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"9.9","Single Cell Type RNA - Endothelial cells [nTPM]":"31.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"3.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"270.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"2.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"98.9","Single Cell Type RNA - granulocytes [nTPM]":"347.6","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"21.0","Single Cell Type RNA - Langerhans cells [nTPM]":"305.6","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"173.1","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"3.4","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.9","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"122.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"12.8","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"10.8","Single Cell Type RNA - Theca cells [nTPM]":"3.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"1.2","Single Cell Type RNA - Urothelial cells [nTPM]":"151.6"},{"Gene":"PTPN11","Gene synonym":["BPTP3","NS1","PTP2C","SH-PTP2","SHP-2","SHP2"],"Ensembl":"ENSG00000179295","Gene description":"Protein tyrosine phosphatase non-receptor type 11","Uniprot":["Q06124"],"Chromosome":"12","Position":"112418351-112509918","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Hydrolase","Protein phosphatase"],"Disease involvement":["Cancer-related genes","Deafness","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB005377"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli rim","Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"74000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 44: Heart - Cardiac muscle contraction","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 54: Cardiomyocytes - Muscle contraction","Subcellular main location":["Nucleoplasm","Nucleoli rim"],"Subcellular additional location":["Actin filaments","Cytosol"],"Antibody RRID":{"CAB005377":"AB_632401"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.73e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.27e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.05e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.22e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.66e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-2"},"Tissue RNA - adipose tissue [nTPM]":"62.9","Tissue RNA - adrenal gland [nTPM]":"36.6","Tissue RNA - amygdala [nTPM]":"74.6","Tissue RNA - appendix [nTPM]":"34.7","Tissue RNA - basal ganglia [nTPM]":"91.7","Tissue RNA - bone marrow [nTPM]":"46.3","Tissue RNA - breast [nTPM]":"37.6","Tissue RNA - cerebellum [nTPM]":"72.7","Tissue RNA - cerebral cortex [nTPM]":"115.7","Tissue RNA - cervix [nTPM]":"37.9","Tissue RNA - choroid plexus [nTPM]":"38.4","Tissue RNA - colon [nTPM]":"32.5","Tissue RNA - duodenum [nTPM]":"27.6","Tissue RNA - endometrium 1 [nTPM]":"37.8","Tissue RNA - epididymis [nTPM]":"28.7","Tissue RNA - esophagus [nTPM]":"38.9","Tissue RNA - fallopian tube [nTPM]":"24.3","Tissue RNA - gallbladder [nTPM]":"29.4","Tissue RNA - heart muscle [nTPM]":"68.7","Tissue RNA - hippocampal formation [nTPM]":"66.1","Tissue RNA - hypothalamus [nTPM]":"85.6","Tissue RNA - kidney [nTPM]":"39.7","Tissue RNA - liver [nTPM]":"53.0","Tissue RNA - lung [nTPM]":"34.4","Tissue RNA - lymph node [nTPM]":"35.6","Tissue RNA - medulla oblongata [nTPM]":"79.0","Tissue RNA - midbrain [nTPM]":"84.1","Tissue RNA - ovary [nTPM]":"26.2","Tissue RNA - pancreas [nTPM]":"31.6","Tissue RNA - parathyroid gland [nTPM]":"53.4","Tissue RNA - pituitary gland [nTPM]":"16.1","Tissue RNA - placenta [nTPM]":"38.0","Tissue RNA - pons [nTPM]":"85.7","Tissue RNA - prostate [nTPM]":"35.2","Tissue RNA - rectum [nTPM]":"30.6","Tissue RNA - retina [nTPM]":"51.8","Tissue RNA - salivary gland [nTPM]":"25.9","Tissue RNA - seminal vesicle [nTPM]":"42.4","Tissue RNA - skeletal muscle [nTPM]":"75.1","Tissue RNA - skin 1 [nTPM]":"32.1","Tissue RNA - small intestine [nTPM]":"26.1","Tissue RNA - smooth muscle [nTPM]":"45.7","Tissue RNA - spinal cord [nTPM]":"83.4","Tissue RNA - spleen [nTPM]":"26.7","Tissue RNA - stomach 1 [nTPM]":"30.4","Tissue RNA - testis [nTPM]":"18.2","Tissue RNA - thalamus [nTPM]":"81.7","Tissue RNA - thymus [nTPM]":"35.5","Tissue RNA - thyroid gland [nTPM]":"46.8","Tissue RNA - tongue [nTPM]":"64.0","Tissue RNA - tonsil [nTPM]":"32.5","Tissue RNA - urinary bladder [nTPM]":"40.1","Tissue RNA - vagina [nTPM]":"23.5","Tissue RNA - white matter [nTPM]":"106.3","Cell RNA - A-431 [nTPM]":"116.9","Cell RNA - A549 [nTPM]":"107.6","Cell RNA - AF22 [nTPM]":"77.0","Cell RNA - AN3-CA [nTPM]":"73.4","Cell RNA - ASC diff [nTPM]":"109.7","Cell RNA - ASC TERT1 [nTPM]":"106.1","Cell RNA - BEWO [nTPM]":"92.7","Cell RNA - BJ [nTPM]":"136.4","Cell RNA - BJ hTERT+ [nTPM]":"148.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"105.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"78.5","Cell RNA - CACO-2 [nTPM]":"107.7","Cell RNA - CAPAN-2 [nTPM]":"43.4","Cell RNA - Daudi [nTPM]":"124.5","Cell RNA - EFO-21 [nTPM]":"69.4","Cell RNA - fHDF\/TERT166 [nTPM]":"127.4","Cell RNA - GAMG [nTPM]":"66.7","Cell RNA - HaCaT [nTPM]":"68.1","Cell RNA - HAP1 [nTPM]":"100.1","Cell RNA - HBEC3-KT [nTPM]":"121.6","Cell RNA - HBF TERT88 [nTPM]":"173.8","Cell RNA - HDLM-2 [nTPM]":"93.1","Cell RNA - HEK 293 [nTPM]":"85.0","Cell RNA - HEL [nTPM]":"181.5","Cell RNA - HeLa [nTPM]":"102.6","Cell RNA - Hep G2 [nTPM]":"59.8","Cell RNA - HHSteC [nTPM]":"109.2","Cell RNA - HL-60 [nTPM]":"145.8","Cell RNA - HMC-1 [nTPM]":"108.0","Cell RNA - HSkMC [nTPM]":"86.6","Cell RNA - hTCEpi [nTPM]":"119.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"113.6","Cell RNA - hTERT-HME1 [nTPM]":"159.8","Cell RNA - hTERT-RPE1 [nTPM]":"101.3","Cell RNA - HUVEC TERT2 [nTPM]":"88.7","Cell RNA - JURKAT [nTPM]":"92.0","Cell RNA - K-562 [nTPM]":"140.2","Cell RNA - Karpas-707 [nTPM]":"41.3","Cell RNA - LHCN-M2 [nTPM]":"103.3","Cell RNA - MCF7 [nTPM]":"83.2","Cell RNA - MOLT-4 [nTPM]":"101.0","Cell RNA - NB-4 [nTPM]":"69.7","Cell RNA - NTERA-2 [nTPM]":"94.1","Cell RNA - OE19 [nTPM]":"112.3","Cell RNA - PC-3 [nTPM]":"73.4","Cell RNA - REH [nTPM]":"102.4","Cell RNA - RH-30 [nTPM]":"114.6","Cell RNA - RPMI-8226 [nTPM]":"70.5","Cell RNA - RPTEC TERT1 [nTPM]":"97.3","Cell RNA - RT4 [nTPM]":"126.7","Cell RNA - SCLC-21H [nTPM]":"53.3","Cell RNA - SH-SY5Y [nTPM]":"66.1","Cell RNA - SiHa [nTPM]":"133.7","Cell RNA - SK-BR-3 [nTPM]":"99.8","Cell RNA - SK-MEL-30 [nTPM]":"85.2","Cell RNA - SuSa [nTPM]":"77.6","Cell RNA - T-47d [nTPM]":"114.8","Cell RNA - THP-1 [nTPM]":"97.8","Cell RNA - TIME [nTPM]":"108.1","Cell RNA - U-138 MG [nTPM]":"122.9","Cell RNA - U-2 OS [nTPM]":"110.0","Cell RNA - U-2197 [nTPM]":"74.2","Cell RNA - U-251 MG [nTPM]":"121.8","Cell RNA - U-266\/70 [nTPM]":"79.4","Cell RNA - U-266\/84 [nTPM]":"141.6","Cell RNA - U-698 [nTPM]":"120.2","Cell RNA - U-87 MG [nTPM]":"102.2","Cell RNA - U-937 [nTPM]":"99.7","Cell RNA - WM-115 [nTPM]":"117.7","Blood RNA - basophil [nTPM]":"32.2","Blood RNA - classical monocyte [nTPM]":"11.7","Blood RNA - eosinophil [nTPM]":"16.8","Blood RNA - gdT-cell [nTPM]":"14.8","Blood RNA - intermediate monocyte [nTPM]":"10.2","Blood RNA - MAIT T-cell [nTPM]":"14.0","Blood RNA - memory B-cell [nTPM]":"18.1","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"12.4","Blood RNA - myeloid DC [nTPM]":"13.6","Blood RNA - naive B-cell [nTPM]":"20.8","Blood RNA - naive CD4 T-cell [nTPM]":"15.3","Blood RNA - naive CD8 T-cell [nTPM]":"11.9","Blood RNA - neutrophil [nTPM]":"10.7","Blood RNA - NK-cell [nTPM]":"12.6","Blood RNA - non-classical monocyte [nTPM]":"13.7","Blood RNA - plasmacytoid DC [nTPM]":"18.3","Blood RNA - T-reg [nTPM]":"10.9","Blood RNA - total PBMC [nTPM]":"7.2","Brain RNA - amygdala [nTPM]":"74.6","Brain RNA - basal ganglia [nTPM]":"91.7","Brain RNA - cerebellum [nTPM]":"72.7","Brain RNA - cerebral cortex [nTPM]":"115.7","Brain RNA - hippocampal formation [nTPM]":"66.1","Brain RNA - hypothalamus [nTPM]":"85.6","Brain RNA - medulla oblongata [nTPM]":"79.0","Brain RNA - midbrain [nTPM]":"84.1","Brain RNA - pons [nTPM]":"85.7","Brain RNA - spinal cord [nTPM]":"83.4","Brain RNA - thalamus [nTPM]":"81.7","Brain RNA - white matter [nTPM]":"106.3","Single Cell Type RNA - Adipocytes [nTPM]":"49.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"68.2","Single Cell Type RNA - Astrocytes [nTPM]":"27.7","Single Cell Type RNA - B-cells [nTPM]":"25.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"39.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"25.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"20.5","Single Cell Type RNA - Bipolar cells [nTPM]":"29.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"40.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"32.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"131.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"41.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.5","Single Cell Type RNA - dendritic cells [nTPM]":"34.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"25.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"33.2","Single Cell Type RNA - Ductal cells [nTPM]":"37.5","Single Cell Type RNA - Early spermatids [nTPM]":"63.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"31.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"92.6","Single Cell Type RNA - Endothelial cells [nTPM]":"46.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"13.1","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"67.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"42.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"25.3","Single Cell Type RNA - Fibroblasts [nTPM]":"35.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.9","Single Cell Type RNA - granulocytes [nTPM]":"28.4","Single Cell Type RNA - Granulosa cells [nTPM]":"33.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"101.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"26.8","Single Cell Type RNA - Horizontal cells [nTPM]":"13.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"54.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"22.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"33.3","Single Cell Type RNA - Langerhans cells [nTPM]":"21.6","Single Cell Type RNA - Late spermatids [nTPM]":"28.5","Single Cell Type RNA - Leydig cells [nTPM]":"51.6","Single Cell Type RNA - Macrophages [nTPM]":"31.8","Single Cell Type RNA - Melanocytes [nTPM]":"14.2","Single Cell Type RNA - Microglial cells [nTPM]":"40.3","Single Cell Type RNA - monocytes [nTPM]":"31.1","Single Cell Type RNA - Muller glia cells [nTPM]":"59.8","Single Cell Type RNA - NK-cells [nTPM]":"29.9","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"32.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"73.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"59.3","Single Cell Type RNA - Paneth cells [nTPM]":"19.6","Single Cell Type RNA - Peritubular cells [nTPM]":"79.7","Single Cell Type RNA - Plasma cells [nTPM]":"37.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"73.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"22.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"58.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"49.2","Single Cell Type RNA - Spermatocytes [nTPM]":"7.1","Single Cell Type RNA - Spermatogonia [nTPM]":"6.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"37.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"35.2","Single Cell Type RNA - T-cells [nTPM]":"31.7","Single Cell Type RNA - Theca cells [nTPM]":"30.5","Single Cell Type RNA - Undifferentiated cells [nTPM]":"22.2","Single Cell Type RNA - Urothelial cells [nTPM]":"66.8"},{"Gene":"RARB","Gene synonym":["HAP","NR1B2","RRB2"],"Ensembl":"ENSG00000077092","Gene description":"Retinoic acid receptor beta","Uniprot":["P10826"],"Chromosome":"3","Position":"25174332-25597932","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","Human disease related genes","Nuclear receptors","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","Receptor"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Microphthalmia","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"41.4","Excitatory neurons":"66.8","Inhibitory neurons":"92.6","Microglial cells":"29.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"13.7","HEK 293":"16.0","hTERT-RPE1":"82.3","WM-115":"36.5"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":"9","RNA mouse brain regional specific nTPM":{"basal ganglia":"109.2"},"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002617","HPA004174"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 11: RPE1 & U-87MG - Synaptic function","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB002617":null,"HPA004174":"AB_1079744"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.53e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.72e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.70e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.71e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.43e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.24e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.28e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.56e-3"},"Tissue RNA - adipose tissue [nTPM]":"4.1","Tissue RNA - adrenal gland [nTPM]":"7.0","Tissue RNA - amygdala [nTPM]":"3.5","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"15.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"6.6","Tissue RNA - cervix [nTPM]":"9.3","Tissue RNA - choroid plexus [nTPM]":"7.2","Tissue RNA - colon [nTPM]":"6.0","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"6.7","Tissue RNA - esophagus [nTPM]":"7.9","Tissue RNA - fallopian tube [nTPM]":"6.0","Tissue RNA - gallbladder [nTPM]":"5.3","Tissue RNA - heart muscle [nTPM]":"14.0","Tissue RNA - hippocampal formation [nTPM]":"3.5","Tissue RNA - hypothalamus [nTPM]":"1.4","Tissue RNA - kidney [nTPM]":"15.1","Tissue RNA - liver [nTPM]":"6.5","Tissue RNA - lung [nTPM]":"5.3","Tissue RNA - lymph node [nTPM]":"6.7","Tissue RNA - medulla oblongata [nTPM]":"3.4","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"6.0","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"14.4","Tissue RNA - pons [nTPM]":"0.9","Tissue RNA - prostate [nTPM]":"12.5","Tissue RNA - rectum [nTPM]":"2.2","Tissue RNA - retina [nTPM]":"13.6","Tissue RNA - salivary gland [nTPM]":"13.1","Tissue RNA - seminal vesicle [nTPM]":"11.2","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"1.1","Tissue RNA - small intestine [nTPM]":"2.0","Tissue RNA - smooth muscle [nTPM]":"5.9","Tissue RNA - spinal cord [nTPM]":"1.4","Tissue RNA - spleen [nTPM]":"4.9","Tissue RNA - stomach 1 [nTPM]":"3.9","Tissue RNA - testis [nTPM]":"0.6","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"1.2","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"5.3","Tissue RNA - tonsil [nTPM]":"4.2","Tissue RNA - urinary bladder [nTPM]":"7.2","Tissue RNA - vagina [nTPM]":"6.1","Tissue RNA - white matter [nTPM]":"3.7","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.9","Cell RNA - AF22 [nTPM]":"1.2","Cell RNA - AN3-CA [nTPM]":"6.4","Cell RNA - ASC diff [nTPM]":"13.7","Cell RNA - ASC TERT1 [nTPM]":"3.6","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"1.6","Cell RNA - BJ hTERT+ [nTPM]":"0.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.6","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"2.5","Cell RNA - GAMG [nTPM]":"0.3","Cell RNA - HaCaT [nTPM]":"0.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.3","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"16.0","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"1.1","Cell RNA - HHSteC [nTPM]":"0.3","Cell RNA - HL-60 [nTPM]":"0.2","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"7.1","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"82.3","Cell RNA - HUVEC TERT2 [nTPM]":"13.4","Cell RNA - JURKAT [nTPM]":"0.1","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"5.6","Cell RNA - LHCN-M2 [nTPM]":"0.1","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.3","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.2","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"8.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.2","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"9.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"1.1","Cell RNA - U-2 OS [nTPM]":"0.1","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"7.0","Cell RNA - U-266\/70 [nTPM]":"0.2","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"5.6","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"36.5","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"3.5","Brain RNA - basal ganglia [nTPM]":"15.0","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"6.6","Brain RNA - hippocampal formation [nTPM]":"3.5","Brain RNA - hypothalamus [nTPM]":"1.4","Brain RNA - medulla oblongata [nTPM]":"3.4","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"0.9","Brain RNA - spinal cord [nTPM]":"1.4","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"3.7","Single Cell Type RNA - Adipocytes [nTPM]":"2.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"41.4","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"6.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"1.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"7.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"12.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"14.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.2","Single Cell Type RNA - dendritic cells [nTPM]":"0.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.2","Single Cell Type RNA - Endothelial cells [nTPM]":"10.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"66.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"7.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"2.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.4","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"92.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.9","Single Cell Type RNA - Langerhans cells [nTPM]":"0.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.3","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"24.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"19.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.4","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"10.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.2","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"6.3","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"2.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"9.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"6.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"9.7"},{"Gene":"RASSF1","Gene synonym":["123F2","NORE2A","RDA32","REH3P21"],"Ensembl":"ENSG00000068028","Gene description":"Ras association domain family member 1","Uniprot":["Q9NS23"],"Chromosome":"3","Position":"50329782-50340980","Protein class":["Human disease related genes","Predicted intracellular proteins","RAS pathway related proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"dendritic cells":"116.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"252.6"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA040735"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - DNA binding","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 24: NB-4 - Immune response","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA040735":"AB_10671692"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.64e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.95e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.60e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.77e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.80e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.58e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.27e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.71e-2"},"Tissue RNA - adipose tissue [nTPM]":"50.1","Tissue RNA - adrenal gland [nTPM]":"18.9","Tissue RNA - amygdala [nTPM]":"19.2","Tissue RNA - appendix [nTPM]":"23.2","Tissue RNA - basal ganglia [nTPM]":"19.5","Tissue RNA - bone marrow [nTPM]":"84.3","Tissue RNA - breast [nTPM]":"46.0","Tissue RNA - cerebellum [nTPM]":"19.6","Tissue RNA - cerebral cortex [nTPM]":"20.1","Tissue RNA - cervix [nTPM]":"44.1","Tissue RNA - choroid plexus [nTPM]":"18.1","Tissue RNA - colon [nTPM]":"28.4","Tissue RNA - duodenum [nTPM]":"15.6","Tissue RNA - endometrium 1 [nTPM]":"29.7","Tissue RNA - epididymis [nTPM]":"11.1","Tissue RNA - esophagus [nTPM]":"26.2","Tissue RNA - fallopian tube [nTPM]":"35.4","Tissue RNA - gallbladder [nTPM]":"21.5","Tissue RNA - heart muscle [nTPM]":"47.7","Tissue RNA - hippocampal formation [nTPM]":"18.4","Tissue RNA - hypothalamus [nTPM]":"19.2","Tissue RNA - kidney [nTPM]":"39.0","Tissue RNA - liver [nTPM]":"24.7","Tissue RNA - lung [nTPM]":"61.2","Tissue RNA - lymph node [nTPM]":"39.5","Tissue RNA - medulla oblongata [nTPM]":"20.8","Tissue RNA - midbrain [nTPM]":"20.0","Tissue RNA - ovary [nTPM]":"31.2","Tissue RNA - pancreas [nTPM]":"35.3","Tissue RNA - parathyroid gland [nTPM]":"7.5","Tissue RNA - pituitary gland [nTPM]":"22.2","Tissue RNA - placenta [nTPM]":"25.8","Tissue RNA - pons [nTPM]":"20.4","Tissue RNA - prostate [nTPM]":"31.6","Tissue RNA - rectum [nTPM]":"11.6","Tissue RNA - retina [nTPM]":"6.1","Tissue RNA - salivary gland [nTPM]":"30.2","Tissue RNA - seminal vesicle [nTPM]":"11.8","Tissue RNA - skeletal muscle [nTPM]":"28.5","Tissue RNA - skin 1 [nTPM]":"38.9","Tissue RNA - small intestine [nTPM]":"39.6","Tissue RNA - smooth muscle [nTPM]":"18.1","Tissue RNA - spinal cord [nTPM]":"20.7","Tissue RNA - spleen [nTPM]":"72.3","Tissue RNA - stomach 1 [nTPM]":"31.7","Tissue RNA - testis [nTPM]":"38.5","Tissue RNA - thalamus [nTPM]":"20.4","Tissue RNA - thymus [nTPM]":"16.3","Tissue RNA - thyroid gland [nTPM]":"29.7","Tissue RNA - tongue [nTPM]":"14.3","Tissue RNA - tonsil [nTPM]":"25.5","Tissue RNA - urinary bladder [nTPM]":"32.3","Tissue RNA - vagina [nTPM]":"37.4","Tissue RNA - white matter [nTPM]":"22.1","Cell RNA - A-431 [nTPM]":"37.4","Cell RNA - A549 [nTPM]":"15.1","Cell RNA - AF22 [nTPM]":"11.1","Cell RNA - AN3-CA [nTPM]":"18.5","Cell RNA - ASC diff [nTPM]":"25.0","Cell RNA - ASC TERT1 [nTPM]":"33.8","Cell RNA - BEWO [nTPM]":"16.2","Cell RNA - BJ [nTPM]":"62.5","Cell RNA - BJ hTERT+ [nTPM]":"40.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"52.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"41.8","Cell RNA - CACO-2 [nTPM]":"34.7","Cell RNA - CAPAN-2 [nTPM]":"27.3","Cell RNA - Daudi [nTPM]":"18.0","Cell RNA - EFO-21 [nTPM]":"9.4","Cell RNA - fHDF\/TERT166 [nTPM]":"67.3","Cell RNA - GAMG [nTPM]":"23.6","Cell RNA - HaCaT [nTPM]":"19.6","Cell RNA - HAP1 [nTPM]":"23.3","Cell RNA - HBEC3-KT [nTPM]":"26.1","Cell RNA - HBF TERT88 [nTPM]":"28.3","Cell RNA - HDLM-2 [nTPM]":"44.6","Cell RNA - HEK 293 [nTPM]":"15.2","Cell RNA - HEL [nTPM]":"61.8","Cell RNA - HeLa [nTPM]":"51.9","Cell RNA - Hep G2 [nTPM]":"18.4","Cell RNA - HHSteC [nTPM]":"28.6","Cell RNA - HL-60 [nTPM]":"61.2","Cell RNA - HMC-1 [nTPM]":"65.2","Cell RNA - HSkMC [nTPM]":"26.1","Cell RNA - hTCEpi [nTPM]":"18.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.0","Cell RNA - hTERT-HME1 [nTPM]":"18.4","Cell RNA - hTERT-RPE1 [nTPM]":"15.4","Cell RNA - HUVEC TERT2 [nTPM]":"23.7","Cell RNA - JURKAT [nTPM]":"21.8","Cell RNA - K-562 [nTPM]":"26.2","Cell RNA - Karpas-707 [nTPM]":"40.7","Cell RNA - LHCN-M2 [nTPM]":"24.1","Cell RNA - MCF7 [nTPM]":"13.1","Cell RNA - MOLT-4 [nTPM]":"23.3","Cell RNA - NB-4 [nTPM]":"81.9","Cell RNA - NTERA-2 [nTPM]":"14.7","Cell RNA - OE19 [nTPM]":"31.2","Cell RNA - PC-3 [nTPM]":"44.9","Cell RNA - REH [nTPM]":"19.0","Cell RNA - RH-30 [nTPM]":"11.4","Cell RNA - RPMI-8226 [nTPM]":"41.4","Cell RNA - RPTEC TERT1 [nTPM]":"15.7","Cell RNA - RT4 [nTPM]":"10.8","Cell RNA - SCLC-21H [nTPM]":"13.0","Cell RNA - SH-SY5Y [nTPM]":"23.9","Cell RNA - SiHa [nTPM]":"55.6","Cell RNA - SK-BR-3 [nTPM]":"37.2","Cell RNA - SK-MEL-30 [nTPM]":"41.5","Cell RNA - SuSa [nTPM]":"11.2","Cell RNA - T-47d [nTPM]":"22.3","Cell RNA - THP-1 [nTPM]":"59.2","Cell RNA - TIME [nTPM]":"22.9","Cell RNA - U-138 MG [nTPM]":"36.1","Cell RNA - U-2 OS [nTPM]":"27.2","Cell RNA - U-2197 [nTPM]":"52.0","Cell RNA - U-251 MG [nTPM]":"31.3","Cell RNA - U-266\/70 [nTPM]":"16.5","Cell RNA - U-266\/84 [nTPM]":"11.7","Cell RNA - U-698 [nTPM]":"39.4","Cell RNA - U-87 MG [nTPM]":"20.3","Cell RNA - U-937 [nTPM]":"75.6","Cell RNA - WM-115 [nTPM]":"66.1","Blood RNA - basophil [nTPM]":"252.6","Blood RNA - classical monocyte [nTPM]":"23.3","Blood RNA - eosinophil [nTPM]":"79.5","Blood RNA - gdT-cell [nTPM]":"77.0","Blood RNA - intermediate monocyte [nTPM]":"41.5","Blood RNA - MAIT T-cell [nTPM]":"48.3","Blood RNA - memory B-cell [nTPM]":"44.3","Blood RNA - memory CD4 T-cell [nTPM]":"24.6","Blood RNA - memory CD8 T-cell [nTPM]":"55.3","Blood RNA - myeloid DC [nTPM]":"24.9","Blood RNA - naive B-cell [nTPM]":"33.6","Blood RNA - naive CD4 T-cell [nTPM]":"15.7","Blood RNA - naive CD8 T-cell [nTPM]":"37.7","Blood RNA - neutrophil [nTPM]":"18.4","Blood RNA - NK-cell [nTPM]":"64.6","Blood RNA - non-classical monocyte [nTPM]":"59.1","Blood RNA - plasmacytoid DC [nTPM]":"18.5","Blood RNA - T-reg [nTPM]":"27.5","Blood RNA - total PBMC [nTPM]":"42.0","Brain RNA - amygdala [nTPM]":"19.2","Brain RNA - basal ganglia [nTPM]":"19.5","Brain RNA - cerebellum [nTPM]":"19.6","Brain RNA - cerebral cortex [nTPM]":"20.1","Brain RNA - hippocampal formation [nTPM]":"18.4","Brain RNA - hypothalamus [nTPM]":"19.2","Brain RNA - medulla oblongata [nTPM]":"20.8","Brain RNA - midbrain [nTPM]":"20.0","Brain RNA - pons [nTPM]":"20.4","Brain RNA - spinal cord [nTPM]":"20.7","Brain RNA - thalamus [nTPM]":"20.4","Brain RNA - white matter [nTPM]":"22.1","Single Cell Type RNA - Adipocytes [nTPM]":"76.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.1","Single Cell Type RNA - Astrocytes [nTPM]":"4.6","Single Cell Type RNA - B-cells [nTPM]":"50.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"73.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"36.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"22.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"34.1","Single Cell Type RNA - Bipolar cells [nTPM]":"11.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"22.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"14.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"12.8","Single Cell Type RNA - Club cells [nTPM]":"14.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"27.5","Single Cell Type RNA - dendritic cells [nTPM]":"116.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"12.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"5.9","Single Cell Type RNA - Ductal cells [nTPM]":"23.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"16.3","Single Cell Type RNA - Endothelial cells [nTPM]":"47.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.7","Single Cell Type RNA - Erythroid cells [nTPM]":"33.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"28.1","Single Cell Type RNA - Fibroblasts [nTPM]":"29.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"27.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.6","Single Cell Type RNA - granulocytes [nTPM]":"57.1","Single Cell Type RNA - Granulosa cells [nTPM]":"9.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"4.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"38.6","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"19.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"27.7","Single Cell Type RNA - Langerhans cells [nTPM]":"43.8","Single Cell Type RNA - Late spermatids [nTPM]":"10.4","Single Cell Type RNA - Leydig cells [nTPM]":"19.0","Single Cell Type RNA - Macrophages [nTPM]":"28.7","Single Cell Type RNA - Melanocytes [nTPM]":"90.7","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"23.2","Single Cell Type RNA - Muller glia cells [nTPM]":"6.1","Single Cell Type RNA - NK-cells [nTPM]":"93.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"40.9","Single Cell Type RNA - Paneth cells [nTPM]":"17.4","Single Cell Type RNA - Peritubular cells [nTPM]":"14.7","Single Cell Type RNA - Plasma cells [nTPM]":"63.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.1","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"19.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"50.4","Single Cell Type RNA - Spermatocytes [nTPM]":"33.1","Single Cell Type RNA - Spermatogonia [nTPM]":"11.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"19.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"16.6","Single Cell Type RNA - T-cells [nTPM]":"67.2","Single Cell Type RNA - Theca cells [nTPM]":"9.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"15.2","Single Cell Type RNA - Urothelial cells [nTPM]":"21.3"},{"Gene":"RB1","Gene synonym":["OSRC","PPP1R130","RB"],"Ensembl":"ENSG00000139687","Gene description":"RB transcriptional corepressor 1","Uniprot":["P06400"],"Chromosome":"13","Position":"48303744-48599436","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"198.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MOLT-4":"187.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000095","CAB016687","HPA050082"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: Antigen presenting cells - Antigen presentation","Tissue expression cluster":"Cluster 16: Immune cells - Immune response","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000095":null,"CAB016687":"AB_1622010","HPA050082":"AB_2681008"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.24e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.86e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.92e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.06e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.67e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.70e-1"},"Tissue RNA - adipose tissue [nTPM]":"20.7","Tissue RNA - adrenal gland [nTPM]":"18.7","Tissue RNA - amygdala [nTPM]":"8.9","Tissue RNA - appendix [nTPM]":"22.8","Tissue RNA - basal ganglia [nTPM]":"9.7","Tissue RNA - bone marrow [nTPM]":"19.3","Tissue RNA - breast [nTPM]":"17.8","Tissue RNA - cerebellum [nTPM]":"12.0","Tissue RNA - cerebral cortex [nTPM]":"13.0","Tissue RNA - cervix [nTPM]":"18.8","Tissue RNA - choroid plexus [nTPM]":"10.9","Tissue RNA - colon [nTPM]":"15.1","Tissue RNA - duodenum [nTPM]":"14.6","Tissue RNA - endometrium 1 [nTPM]":"15.7","Tissue RNA - epididymis [nTPM]":"21.2","Tissue RNA - esophagus [nTPM]":"21.9","Tissue RNA - fallopian tube [nTPM]":"13.1","Tissue RNA - gallbladder [nTPM]":"17.3","Tissue RNA - heart muscle [nTPM]":"17.8","Tissue RNA - hippocampal formation [nTPM]":"8.5","Tissue RNA - hypothalamus [nTPM]":"10.9","Tissue RNA - kidney [nTPM]":"18.4","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"18.1","Tissue RNA - lymph node [nTPM]":"30.7","Tissue RNA - medulla oblongata [nTPM]":"13.9","Tissue RNA - midbrain [nTPM]":"10.3","Tissue RNA - ovary [nTPM]":"11.5","Tissue RNA - pancreas [nTPM]":"9.2","Tissue RNA - parathyroid gland [nTPM]":"20.5","Tissue RNA - pituitary gland [nTPM]":"6.5","Tissue RNA - placenta [nTPM]":"24.9","Tissue RNA - pons [nTPM]":"13.4","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"17.1","Tissue RNA - retina [nTPM]":"12.5","Tissue RNA - salivary gland [nTPM]":"16.9","Tissue RNA - seminal vesicle [nTPM]":"15.9","Tissue RNA - skeletal muscle [nTPM]":"19.0","Tissue RNA - skin 1 [nTPM]":"23.6","Tissue RNA - small intestine [nTPM]":"15.6","Tissue RNA - smooth muscle [nTPM]":"18.3","Tissue RNA - spinal cord [nTPM]":"11.6","Tissue RNA - spleen [nTPM]":"24.8","Tissue RNA - stomach 1 [nTPM]":"16.3","Tissue RNA - testis [nTPM]":"12.9","Tissue RNA - thalamus [nTPM]":"9.3","Tissue RNA - thymus [nTPM]":"34.2","Tissue RNA - thyroid gland [nTPM]":"22.4","Tissue RNA - tongue [nTPM]":"21.2","Tissue RNA - tonsil [nTPM]":"30.1","Tissue RNA - urinary bladder [nTPM]":"19.8","Tissue RNA - vagina [nTPM]":"10.6","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"29.1","Cell RNA - A549 [nTPM]":"15.8","Cell RNA - AF22 [nTPM]":"40.9","Cell RNA - AN3-CA [nTPM]":"44.2","Cell RNA - ASC diff [nTPM]":"19.8","Cell RNA - ASC TERT1 [nTPM]":"22.8","Cell RNA - BEWO [nTPM]":"18.5","Cell RNA - BJ [nTPM]":"56.6","Cell RNA - BJ hTERT+ [nTPM]":"45.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"57.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"48.3","Cell RNA - CACO-2 [nTPM]":"13.4","Cell RNA - CAPAN-2 [nTPM]":"49.8","Cell RNA - Daudi [nTPM]":"37.3","Cell RNA - EFO-21 [nTPM]":"12.8","Cell RNA - fHDF\/TERT166 [nTPM]":"37.4","Cell RNA - GAMG [nTPM]":"31.7","Cell RNA - HaCaT [nTPM]":"39.6","Cell RNA - HAP1 [nTPM]":"53.7","Cell RNA - HBEC3-KT [nTPM]":"44.8","Cell RNA - HBF TERT88 [nTPM]":"86.6","Cell RNA - HDLM-2 [nTPM]":"53.0","Cell RNA - HEK 293 [nTPM]":"20.8","Cell RNA - HEL [nTPM]":"68.5","Cell RNA - HeLa [nTPM]":"29.4","Cell RNA - Hep G2 [nTPM]":"22.7","Cell RNA - HHSteC [nTPM]":"21.1","Cell RNA - HL-60 [nTPM]":"59.5","Cell RNA - HMC-1 [nTPM]":"62.0","Cell RNA - HSkMC [nTPM]":"12.9","Cell RNA - hTCEpi [nTPM]":"27.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"37.3","Cell RNA - hTERT-HME1 [nTPM]":"47.1","Cell RNA - hTERT-RPE1 [nTPM]":"47.8","Cell RNA - HUVEC TERT2 [nTPM]":"40.1","Cell RNA - JURKAT [nTPM]":"90.1","Cell RNA - K-562 [nTPM]":"23.4","Cell RNA - Karpas-707 [nTPM]":"29.6","Cell RNA - LHCN-M2 [nTPM]":"66.4","Cell RNA - MCF7 [nTPM]":"13.7","Cell RNA - MOLT-4 [nTPM]":"187.2","Cell RNA - NB-4 [nTPM]":"29.8","Cell RNA - NTERA-2 [nTPM]":"20.0","Cell RNA - OE19 [nTPM]":"65.6","Cell RNA - PC-3 [nTPM]":"17.3","Cell RNA - REH [nTPM]":"79.8","Cell RNA - RH-30 [nTPM]":"41.1","Cell RNA - RPMI-8226 [nTPM]":"43.0","Cell RNA - RPTEC TERT1 [nTPM]":"59.6","Cell RNA - RT4 [nTPM]":"27.6","Cell RNA - SCLC-21H [nTPM]":"2.0","Cell RNA - SH-SY5Y [nTPM]":"41.8","Cell RNA - SiHa [nTPM]":"55.1","Cell RNA - SK-BR-3 [nTPM]":"27.3","Cell RNA - SK-MEL-30 [nTPM]":"46.2","Cell RNA - SuSa [nTPM]":"36.2","Cell RNA - T-47d [nTPM]":"29.8","Cell RNA - THP-1 [nTPM]":"76.3","Cell RNA - TIME [nTPM]":"32.1","Cell RNA - U-138 MG [nTPM]":"35.3","Cell RNA - U-2 OS [nTPM]":"23.3","Cell RNA - U-2197 [nTPM]":"43.7","Cell RNA - U-251 MG [nTPM]":"51.2","Cell RNA - U-266\/70 [nTPM]":"13.1","Cell RNA - U-266\/84 [nTPM]":"3.9","Cell RNA - U-698 [nTPM]":"0.4","Cell RNA - U-87 MG [nTPM]":"18.8","Cell RNA - U-937 [nTPM]":"36.7","Cell RNA - WM-115 [nTPM]":"48.9","Blood RNA - basophil [nTPM]":"23.8","Blood RNA - classical monocyte [nTPM]":"14.9","Blood RNA - eosinophil [nTPM]":"8.8","Blood RNA - gdT-cell [nTPM]":"6.9","Blood RNA - intermediate monocyte [nTPM]":"19.9","Blood RNA - MAIT T-cell [nTPM]":"5.6","Blood RNA - memory B-cell [nTPM]":"30.2","Blood RNA - memory CD4 T-cell [nTPM]":"5.7","Blood RNA - memory CD8 T-cell [nTPM]":"6.9","Blood RNA - myeloid DC [nTPM]":"15.2","Blood RNA - naive B-cell [nTPM]":"29.4","Blood RNA - naive CD4 T-cell [nTPM]":"4.8","Blood RNA - naive CD8 T-cell [nTPM]":"5.6","Blood RNA - neutrophil [nTPM]":"20.6","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"20.9","Blood RNA - plasmacytoid DC [nTPM]":"16.9","Blood RNA - T-reg [nTPM]":"7.4","Blood RNA - total PBMC [nTPM]":"7.1","Brain RNA - amygdala [nTPM]":"8.9","Brain RNA - basal ganglia [nTPM]":"9.7","Brain RNA - cerebellum [nTPM]":"12.0","Brain RNA - cerebral cortex [nTPM]":"13.0","Brain RNA - hippocampal formation [nTPM]":"8.5","Brain RNA - hypothalamus [nTPM]":"10.9","Brain RNA - medulla oblongata [nTPM]":"13.9","Brain RNA - midbrain [nTPM]":"10.3","Brain RNA - pons [nTPM]":"13.4","Brain RNA - spinal cord [nTPM]":"11.6","Brain RNA - thalamus [nTPM]":"9.3","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"59.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"19.6","Single Cell Type RNA - Astrocytes [nTPM]":"75.4","Single Cell Type RNA - B-cells [nTPM]":"97.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"23.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"27.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"63.2","Single Cell Type RNA - Bipolar cells [nTPM]":"17.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"26.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"21.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"18.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"19.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.1","Single Cell Type RNA - dendritic cells [nTPM]":"50.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"17.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"19.3","Single Cell Type RNA - Early spermatids [nTPM]":"28.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.2","Single Cell Type RNA - Endothelial cells [nTPM]":"46.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"17.5","Single Cell Type RNA - Erythroid cells [nTPM]":"50.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"99.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"11.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.6","Single Cell Type RNA - Fibroblasts [nTPM]":"22.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"29.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"40.4","Single Cell Type RNA - granulocytes [nTPM]":"12.0","Single Cell Type RNA - Granulosa cells [nTPM]":"25.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"35.7","Single Cell Type RNA - Hepatocytes [nTPM]":"17.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"77.4","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"98.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"20.0","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"105.3","Single Cell Type RNA - Langerhans cells [nTPM]":"198.9","Single Cell Type RNA - Late spermatids [nTPM]":"13.9","Single Cell Type RNA - Leydig cells [nTPM]":"26.1","Single Cell Type RNA - Macrophages [nTPM]":"104.2","Single Cell Type RNA - Melanocytes [nTPM]":"26.6","Single Cell Type RNA - Microglial cells [nTPM]":"152.7","Single Cell Type RNA - monocytes [nTPM]":"93.7","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"22.6","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"101.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"98.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.4","Single Cell Type RNA - Paneth cells [nTPM]":"10.7","Single Cell Type RNA - Peritubular cells [nTPM]":"28.6","Single Cell Type RNA - Plasma cells [nTPM]":"69.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"24.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"15.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"23.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"25.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"28.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"32.3","Single Cell Type RNA - Spermatocytes [nTPM]":"33.0","Single Cell Type RNA - Spermatogonia [nTPM]":"21.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"38.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.4","Single Cell Type RNA - T-cells [nTPM]":"38.3","Single Cell Type RNA - Theca cells [nTPM]":"21.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"16.6","Single Cell Type RNA - Urothelial cells [nTPM]":"18.0"},{"Gene":"REL","Gene synonym":["c-Rel","I-Rel"],"Ensembl":"ENSG00000162924","Gene description":"REL proto-oncogene, NF-kB subunit","Uniprot":["Q04864"],"Chromosome":"2","Position":"60881521-60931612","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","RAS pathway related proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"37.4"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Langerhans cells":"2061.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Daudi":"61.2","U-698":"109.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004404"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: B-cells - Adaptive immune response","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004404":"AB_670194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.77e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.41e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.15e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.38e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.37e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.82e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.53e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.85e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.8","Tissue RNA - adrenal gland [nTPM]":"4.5","Tissue RNA - amygdala [nTPM]":"2.2","Tissue RNA - appendix [nTPM]":"14.1","Tissue RNA - basal ganglia [nTPM]":"1.8","Tissue RNA - bone marrow [nTPM]":"37.4","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"8.6","Tissue RNA - cerebral cortex [nTPM]":"4.2","Tissue RNA - cervix [nTPM]":"4.6","Tissue RNA - choroid plexus [nTPM]":"0.4","Tissue RNA - colon [nTPM]":"4.6","Tissue RNA - duodenum [nTPM]":"4.7","Tissue RNA - endometrium 1 [nTPM]":"5.7","Tissue RNA - epididymis [nTPM]":"2.7","Tissue RNA - esophagus [nTPM]":"6.0","Tissue RNA - fallopian tube [nTPM]":"3.2","Tissue RNA - gallbladder [nTPM]":"8.2","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"2.9","Tissue RNA - kidney [nTPM]":"3.4","Tissue RNA - liver [nTPM]":"7.3","Tissue RNA - lung [nTPM]":"6.7","Tissue RNA - lymph node [nTPM]":"15.8","Tissue RNA - medulla oblongata [nTPM]":"3.0","Tissue RNA - midbrain [nTPM]":"1.7","Tissue RNA - ovary [nTPM]":"5.0","Tissue RNA - pancreas [nTPM]":"5.0","Tissue RNA - parathyroid gland [nTPM]":"6.2","Tissue RNA - pituitary gland [nTPM]":"1.9","Tissue RNA - placenta [nTPM]":"5.5","Tissue RNA - pons [nTPM]":"2.3","Tissue RNA - prostate [nTPM]":"4.1","Tissue RNA - rectum [nTPM]":"4.9","Tissue RNA - retina [nTPM]":"9.8","Tissue RNA - salivary gland [nTPM]":"4.6","Tissue RNA - seminal vesicle [nTPM]":"2.7","Tissue RNA - skeletal muscle [nTPM]":"2.4","Tissue RNA - skin 1 [nTPM]":"8.3","Tissue RNA - small intestine [nTPM]":"5.2","Tissue RNA - smooth muscle [nTPM]":"3.5","Tissue RNA - spinal cord [nTPM]":"0.5","Tissue RNA - spleen [nTPM]":"11.1","Tissue RNA - stomach 1 [nTPM]":"5.8","Tissue RNA - testis [nTPM]":"3.5","Tissue RNA - thalamus [nTPM]":"2.4","Tissue RNA - thymus [nTPM]":"9.2","Tissue RNA - thyroid gland [nTPM]":"4.1","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"16.3","Tissue RNA - urinary bladder [nTPM]":"13.1","Tissue RNA - vagina [nTPM]":"3.3","Tissue RNA - white matter [nTPM]":"3.4","Cell RNA - A-431 [nTPM]":"7.2","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"3.4","Cell RNA - AN3-CA [nTPM]":"4.5","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"2.6","Cell RNA - BEWO [nTPM]":"7.3","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"3.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"2.1","Cell RNA - CACO-2 [nTPM]":"3.2","Cell RNA - CAPAN-2 [nTPM]":"6.0","Cell RNA - Daudi [nTPM]":"61.2","Cell RNA - EFO-21 [nTPM]":"6.4","Cell RNA - fHDF\/TERT166 [nTPM]":"2.2","Cell RNA - GAMG [nTPM]":"4.6","Cell RNA - HaCaT [nTPM]":"7.7","Cell RNA - HAP1 [nTPM]":"5.3","Cell RNA - HBEC3-KT [nTPM]":"3.9","Cell RNA - HBF TERT88 [nTPM]":"4.0","Cell RNA - HDLM-2 [nTPM]":"7.0","Cell RNA - HEK 293 [nTPM]":"5.0","Cell RNA - HEL [nTPM]":"6.3","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"3.5","Cell RNA - HHSteC [nTPM]":"1.5","Cell RNA - HL-60 [nTPM]":"13.3","Cell RNA - HMC-1 [nTPM]":"7.1","Cell RNA - HSkMC [nTPM]":"2.3","Cell RNA - hTCEpi [nTPM]":"10.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.6","Cell RNA - hTERT-HME1 [nTPM]":"7.0","Cell RNA - hTERT-RPE1 [nTPM]":"3.0","Cell RNA - HUVEC TERT2 [nTPM]":"4.8","Cell RNA - JURKAT [nTPM]":"6.6","Cell RNA - K-562 [nTPM]":"7.6","Cell RNA - Karpas-707 [nTPM]":"4.3","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"4.0","Cell RNA - MOLT-4 [nTPM]":"9.1","Cell RNA - NB-4 [nTPM]":"5.6","Cell RNA - NTERA-2 [nTPM]":"4.2","Cell RNA - OE19 [nTPM]":"5.0","Cell RNA - PC-3 [nTPM]":"1.8","Cell RNA - REH [nTPM]":"12.0","Cell RNA - RH-30 [nTPM]":"8.8","Cell RNA - RPMI-8226 [nTPM]":"2.7","Cell RNA - RPTEC TERT1 [nTPM]":"2.8","Cell RNA - RT4 [nTPM]":"24.5","Cell RNA - SCLC-21H [nTPM]":"3.3","Cell RNA - SH-SY5Y [nTPM]":"3.5","Cell RNA - SiHa [nTPM]":"6.4","Cell RNA - SK-BR-3 [nTPM]":"7.9","Cell RNA - SK-MEL-30 [nTPM]":"2.3","Cell RNA - SuSa [nTPM]":"5.0","Cell RNA - T-47d [nTPM]":"4.6","Cell RNA - THP-1 [nTPM]":"5.5","Cell RNA - TIME [nTPM]":"5.6","Cell RNA - U-138 MG [nTPM]":"5.0","Cell RNA - U-2 OS [nTPM]":"6.0","Cell RNA - U-2197 [nTPM]":"3.5","Cell RNA - U-251 MG [nTPM]":"3.8","Cell RNA - U-266\/70 [nTPM]":"5.4","Cell RNA - U-266\/84 [nTPM]":"2.8","Cell RNA - U-698 [nTPM]":"109.7","Cell RNA - U-87 MG [nTPM]":"3.0","Cell RNA - U-937 [nTPM]":"10.9","Cell RNA - WM-115 [nTPM]":"2.7","Blood RNA - basophil [nTPM]":"3.4","Blood RNA - classical monocyte [nTPM]":"4.1","Blood RNA - eosinophil [nTPM]":"2.6","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"4.5","Blood RNA - MAIT T-cell [nTPM]":"2.0","Blood RNA - memory B-cell [nTPM]":"5.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.5","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"3.5","Blood RNA - naive B-cell [nTPM]":"7.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.0","Blood RNA - naive CD8 T-cell [nTPM]":"2.1","Blood RNA - neutrophil [nTPM]":"5.0","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"5.7","Blood RNA - plasmacytoid DC [nTPM]":"3.1","Blood RNA - T-reg [nTPM]":"1.9","Blood RNA - total PBMC [nTPM]":"2.3","Brain RNA - amygdala [nTPM]":"2.2","Brain RNA - basal ganglia [nTPM]":"1.8","Brain RNA - cerebellum [nTPM]":"8.6","Brain RNA - cerebral cortex [nTPM]":"4.2","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"2.9","Brain RNA - medulla oblongata [nTPM]":"3.0","Brain RNA - midbrain [nTPM]":"1.7","Brain RNA - pons [nTPM]":"2.3","Brain RNA - spinal cord [nTPM]":"0.5","Brain RNA - thalamus [nTPM]":"2.4","Brain RNA - white matter [nTPM]":"3.4","Single Cell Type RNA - Adipocytes [nTPM]":"67.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"320.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"325.8","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"430.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"517.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"123.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"194.6","Single Cell Type RNA - Bipolar cells [nTPM]":"82.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"95.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"165.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"51.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"85.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"29.0","Single Cell Type RNA - dendritic cells [nTPM]":"469.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"59.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"31.7","Single Cell Type RNA - Early spermatids [nTPM]":"4.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"150.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"79.5","Single Cell Type RNA - Endothelial cells [nTPM]":"103.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"42.5","Single Cell Type RNA - Erythroid cells [nTPM]":"37.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"16.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"29.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"58.5","Single Cell Type RNA - Fibroblasts [nTPM]":"97.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"96.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"300.1","Single Cell Type RNA - granulocytes [nTPM]":"412.1","Single Cell Type RNA - Granulosa cells [nTPM]":"82.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"30.0","Single Cell Type RNA - Hepatocytes [nTPM]":"19.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.7","Single Cell Type RNA - Horizontal cells [nTPM]":"58.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"16.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"49.1","Single Cell Type RNA - Ionocytes [nTPM]":"46.8","Single Cell Type RNA - Kupffer cells [nTPM]":"141.5","Single Cell Type RNA - Langerhans cells [nTPM]":"2061.4","Single Cell Type RNA - Late spermatids [nTPM]":"3.4","Single Cell Type RNA - Leydig cells [nTPM]":"15.5","Single Cell Type RNA - Macrophages [nTPM]":"463.9","Single Cell Type RNA - Melanocytes [nTPM]":"135.2","Single Cell Type RNA - Microglial cells [nTPM]":"42.2","Single Cell Type RNA - monocytes [nTPM]":"451.1","Single Cell Type RNA - Muller glia cells [nTPM]":"21.3","Single Cell Type RNA - NK-cells [nTPM]":"145.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.1","Single Cell Type RNA - Paneth cells [nTPM]":"46.6","Single Cell Type RNA - Peritubular cells [nTPM]":"23.7","Single Cell Type RNA - Plasma cells [nTPM]":"119.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"99.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"34.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"153.1","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"56.2","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"65.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"73.9","Single Cell Type RNA - Spermatocytes [nTPM]":"51.5","Single Cell Type RNA - Spermatogonia [nTPM]":"38.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"158.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"463.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"77.6","Single Cell Type RNA - T-cells [nTPM]":"303.7","Single Cell Type RNA - Theca cells [nTPM]":"21.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"50.1","Single Cell Type RNA - Urothelial cells [nTPM]":"260.6"},{"Gene":"RET","Gene synonym":["CDHF12","CDHR16","HSCR1","MEN2A","MEN2B","MTC1","PTC","RET51"],"Ensembl":"ENSG00000165731","Gene description":"Ret proto-oncogene","Uniprot":["P07949"],"Chromosome":"10","Position":"43077064-43130351","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Hirschsprung disease","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"adrenal gland":"20.8","brain":"27.3","parathyroid gland":"31.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Horizontal cells":"79.1","Ionocytes":"26.4","Skeletal myocytes":"23.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"breast cancer":"11.0"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"MCF7":"74.6","NB-4":"42.2","SH-SY5Y":"329.3","THP-1":"95.9"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Group enriched","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"midbrain":"53.3","spinal cord":"19.4"},"Antibody":["CAB002581","HPA008356","HPA008495"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Plasma membrane","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"2100000","Blood expression cluster":"Cluster 47: Plasmacytoid DCs - Protein folding","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":["Golgi apparatus","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"CAB002581":"AB_563673","HPA008356":"AB_1847232","HPA008495":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.94e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.49e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.02e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.13e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.62e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.01e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.35e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.28e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.67e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"1.8","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"1.0","Tissue RNA - appendix [nTPM]":"1.3","Tissue RNA - basal ganglia [nTPM]":"0.9","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"1.1","Tissue RNA - cerebellum [nTPM]":"5.1","Tissue RNA - cerebral cortex [nTPM]":"5.6","Tissue RNA - cervix [nTPM]":"1.0","Tissue RNA - choroid plexus [nTPM]":"0.2","Tissue RNA - colon [nTPM]":"3.4","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"0.6","Tissue RNA - epididymis [nTPM]":"0.3","Tissue RNA - esophagus [nTPM]":"0.4","Tissue RNA - fallopian tube [nTPM]":"0.5","Tissue RNA - gallbladder [nTPM]":"0.6","Tissue RNA - heart muscle [nTPM]":"2.2","Tissue RNA - hippocampal formation [nTPM]":"0.3","Tissue RNA - hypothalamus [nTPM]":"5.5","Tissue RNA - kidney [nTPM]":"0.9","Tissue RNA - liver [nTPM]":"3.0","Tissue RNA - lung [nTPM]":"0.4","Tissue RNA - lymph node [nTPM]":"0.6","Tissue RNA - medulla oblongata [nTPM]":"14.4","Tissue RNA - midbrain [nTPM]":"27.3","Tissue RNA - ovary [nTPM]":"0.4","Tissue RNA - pancreas [nTPM]":"1.3","Tissue RNA - parathyroid gland [nTPM]":"31.8","Tissue RNA - pituitary gland [nTPM]":"5.3","Tissue RNA - placenta [nTPM]":"0.5","Tissue RNA - pons [nTPM]":"12.0","Tissue RNA - prostate [nTPM]":"1.8","Tissue RNA - rectum [nTPM]":"1.4","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"5.1","Tissue RNA - seminal vesicle [nTPM]":"2.0","Tissue RNA - skeletal muscle [nTPM]":"5.9","Tissue RNA - skin 1 [nTPM]":"0.9","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"1.0","Tissue RNA - spinal cord [nTPM]":"4.8","Tissue RNA - spleen [nTPM]":"0.2","Tissue RNA - stomach 1 [nTPM]":"2.2","Tissue RNA - testis [nTPM]":"2.7","Tissue RNA - thalamus [nTPM]":"7.6","Tissue RNA - thymus [nTPM]":"1.6","Tissue RNA - thyroid gland [nTPM]":"0.8","Tissue RNA - tongue [nTPM]":"3.1","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.6","Tissue RNA - vagina [nTPM]":"1.4","Tissue RNA - white matter [nTPM]":"5.8","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.4","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"1.7","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.7","Cell RNA - BJ hTERT+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.6","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.3","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"7.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.2","Cell RNA - hTCEpi [nTPM]":"0.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"74.6","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"42.2","Cell RNA - NTERA-2 [nTPM]":"7.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.2","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"4.7","Cell RNA - SH-SY5Y [nTPM]":"329.3","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.5","Cell RNA - T-47d [nTPM]":"4.1","Cell RNA - THP-1 [nTPM]":"95.9","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.4","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.1","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.2","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.9","Blood RNA - plasmacytoid DC [nTPM]":"0.7","Blood RNA - T-reg [nTPM]":"0.1","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.0","Brain RNA - basal ganglia [nTPM]":"0.9","Brain RNA - cerebellum [nTPM]":"5.1","Brain RNA - cerebral cortex [nTPM]":"5.6","Brain RNA - hippocampal formation [nTPM]":"0.3","Brain RNA - hypothalamus [nTPM]":"5.5","Brain RNA - medulla oblongata [nTPM]":"14.4","Brain RNA - midbrain [nTPM]":"27.3","Brain RNA - pons [nTPM]":"12.0","Brain RNA - spinal cord [nTPM]":"4.8","Brain RNA - thalamus [nTPM]":"7.6","Brain RNA - white matter [nTPM]":"5.8","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.5","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"6.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.5","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"1.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"4.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"2.3","Single Cell Type RNA - Fibroblasts [nTPM]":"6.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"1.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"79.1","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.9","Single Cell Type RNA - Ionocytes [nTPM]":"26.4","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.5","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"0.5","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.8","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"23.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.2","Single Cell Type RNA - Spermatocytes [nTPM]":"1.1","Single Cell Type RNA - Spermatogonia [nTPM]":"4.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.2","Single Cell Type RNA - Theca cells [nTPM]":"0.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.2","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ROS1","Gene synonym":["c-ros-1","MCF3","ROS"],"Ensembl":"ENSG00000047936","Gene description":"ROS proto-oncogene 1, receptor tyrosine kinase","Uniprot":["P08922"],"Chromosome":"6","Position":"117287353-117425942","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Kinase","Receptor","Transferase","Tyrosine-protein kinase"],"Disease involvement":["Cancer-related genes","FDA approved drug targets","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"18","RNA tissue specific nTPM":{"epididymis":"58.6","lung":"31.7"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Alveolar cells type 2":"78.5"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"13","RNA cancer specific FPKM":{"lung cancer":"6.9"},"RNA brain regional specificity":"Region enriched","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":"4","RNA brain regional specific nTPM":{"cerebral cortex":"2.4"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"GAMG":"19.3","HSkMC":"10.1","hTCEpi":"21.7","LHCN-M2":"14.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049098","HPA072424"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 30: Epididymis - Antimicrobial activity","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049098":"AB_2680628","HPA072424":"AB_2686519"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.18e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.64e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.37e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.57e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.05e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.00e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-12"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.81e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.12e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"2.4","Tissue RNA - cervix [nTPM]":"0.2","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.4","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"58.6","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.6","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"31.7","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.4","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.4","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"2.2","Tissue RNA - skeletal muscle [nTPM]":"0.4","Tissue RNA - skin 1 [nTPM]":"0.3","Tissue RNA - small intestine [nTPM]":"0.2","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"0.4","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.2","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.2","Cell RNA - BJ hTERT+ [nTPM]":"0.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"19.3","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"2.2","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"10.1","Cell RNA - hTCEpi [nTPM]":"21.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.2","Cell RNA - hTERT-HME1 [nTPM]":"1.9","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"14.9","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.2","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.8","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"2.8","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"3.1","Cell RNA - U-2 OS [nTPM]":"1.7","Cell RNA - U-2197 [nTPM]":"0.2","Cell RNA - U-251 MG [nTPM]":"2.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"1.9","Cell RNA - U-937 [nTPM]":"3.5","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"2.4","Brain RNA - hippocampal formation [nTPM]":"0.6","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.2","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"78.5","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"3.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.2","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"1.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.1","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"RUNX1","Gene synonym":["AML1","AMLCR1","CBFA2","PEBP2A2"],"Ensembl":"ENSG00000159216","Gene description":"RUNX family transcription factor 1","Uniprot":["Q01196"],"Chromosome":"21","Position":"34787801-36004667","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Breast glandular cells":"175.5","Glandular and luminal cells":"155.8","Microglial cells":"195.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"23.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"23.9"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"251.3","HMC-1":"145.3","JURKAT":"226.3"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA004176","HPA037912"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 18: Basophils - Vesicular transport","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 35: Glandular cells - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA004176":"AB_1078412","HPA037912":"AB_2675733"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.06e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.87e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.15e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.12e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.44e-15"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.17e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.47e-2"},"Tissue RNA - adipose tissue [nTPM]":"14.8","Tissue RNA - adrenal gland [nTPM]":"3.8","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"20.3","Tissue RNA - basal ganglia [nTPM]":"2.1","Tissue RNA - bone marrow [nTPM]":"45.5","Tissue RNA - breast [nTPM]":"27.1","Tissue RNA - cerebellum [nTPM]":"2.6","Tissue RNA - cerebral cortex [nTPM]":"4.0","Tissue RNA - cervix [nTPM]":"15.3","Tissue RNA - choroid plexus [nTPM]":"5.1","Tissue RNA - colon [nTPM]":"6.7","Tissue RNA - duodenum [nTPM]":"5.1","Tissue RNA - endometrium 1 [nTPM]":"3.3","Tissue RNA - epididymis [nTPM]":"3.1","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"4.7","Tissue RNA - gallbladder [nTPM]":"16.0","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"2.8","Tissue RNA - hypothalamus [nTPM]":"3.2","Tissue RNA - kidney [nTPM]":"4.6","Tissue RNA - liver [nTPM]":"7.0","Tissue RNA - lung [nTPM]":"22.4","Tissue RNA - lymph node [nTPM]":"11.3","Tissue RNA - medulla oblongata [nTPM]":"6.0","Tissue RNA - midbrain [nTPM]":"4.3","Tissue RNA - ovary [nTPM]":"6.3","Tissue RNA - pancreas [nTPM]":"4.0","Tissue RNA - parathyroid gland [nTPM]":"1.5","Tissue RNA - pituitary gland [nTPM]":"5.1","Tissue RNA - placenta [nTPM]":"8.5","Tissue RNA - pons [nTPM]":"6.5","Tissue RNA - prostate [nTPM]":"13.5","Tissue RNA - rectum [nTPM]":"6.5","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"39.2","Tissue RNA - seminal vesicle [nTPM]":"3.5","Tissue RNA - skeletal muscle [nTPM]":"18.9","Tissue RNA - skin 1 [nTPM]":"11.6","Tissue RNA - small intestine [nTPM]":"6.8","Tissue RNA - smooth muscle [nTPM]":"9.2","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"10.2","Tissue RNA - stomach 1 [nTPM]":"16.9","Tissue RNA - testis [nTPM]":"3.8","Tissue RNA - thalamus [nTPM]":"9.1","Tissue RNA - thymus [nTPM]":"28.2","Tissue RNA - thyroid gland [nTPM]":"4.8","Tissue RNA - tongue [nTPM]":"1.4","Tissue RNA - tonsil [nTPM]":"9.9","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"7.9","Cell RNA - A-431 [nTPM]":"50.9","Cell RNA - A549 [nTPM]":"3.8","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.3","Cell RNA - ASC diff [nTPM]":"12.5","Cell RNA - ASC TERT1 [nTPM]":"16.0","Cell RNA - BEWO [nTPM]":"32.0","Cell RNA - BJ [nTPM]":"28.1","Cell RNA - BJ hTERT+ [nTPM]":"28.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"15.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.6","Cell RNA - CACO-2 [nTPM]":"2.5","Cell RNA - CAPAN-2 [nTPM]":"37.7","Cell RNA - Daudi [nTPM]":"24.9","Cell RNA - EFO-21 [nTPM]":"1.8","Cell RNA - fHDF\/TERT166 [nTPM]":"24.9","Cell RNA - GAMG [nTPM]":"25.5","Cell RNA - HaCaT [nTPM]":"45.0","Cell RNA - HAP1 [nTPM]":"3.0","Cell RNA - HBEC3-KT [nTPM]":"33.6","Cell RNA - HBF TERT88 [nTPM]":"21.4","Cell RNA - HDLM-2 [nTPM]":"38.7","Cell RNA - HEK 293 [nTPM]":"3.8","Cell RNA - HEL [nTPM]":"251.3","Cell RNA - HeLa [nTPM]":"10.1","Cell RNA - Hep G2 [nTPM]":"11.6","Cell RNA - HHSteC [nTPM]":"22.9","Cell RNA - HL-60 [nTPM]":"29.4","Cell RNA - HMC-1 [nTPM]":"145.3","Cell RNA - HSkMC [nTPM]":"30.9","Cell RNA - hTCEpi [nTPM]":"19.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"46.6","Cell RNA - hTERT-HME1 [nTPM]":"45.6","Cell RNA - hTERT-RPE1 [nTPM]":"21.2","Cell RNA - HUVEC TERT2 [nTPM]":"8.8","Cell RNA - JURKAT [nTPM]":"226.3","Cell RNA - K-562 [nTPM]":"17.3","Cell RNA - Karpas-707 [nTPM]":"14.1","Cell RNA - LHCN-M2 [nTPM]":"32.7","Cell RNA - MCF7 [nTPM]":"10.7","Cell RNA - MOLT-4 [nTPM]":"119.3","Cell RNA - NB-4 [nTPM]":"46.5","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"27.4","Cell RNA - PC-3 [nTPM]":"14.5","Cell RNA - REH [nTPM]":"119.2","Cell RNA - RH-30 [nTPM]":"84.6","Cell RNA - RPMI-8226 [nTPM]":"15.3","Cell RNA - RPTEC TERT1 [nTPM]":"20.7","Cell RNA - RT4 [nTPM]":"19.9","Cell RNA - SCLC-21H [nTPM]":"1.4","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"28.9","Cell RNA - SK-BR-3 [nTPM]":"7.2","Cell RNA - SK-MEL-30 [nTPM]":"10.5","Cell RNA - SuSa [nTPM]":"6.8","Cell RNA - T-47d [nTPM]":"14.7","Cell RNA - THP-1 [nTPM]":"67.8","Cell RNA - TIME [nTPM]":"37.0","Cell RNA - U-138 MG [nTPM]":"25.1","Cell RNA - U-2 OS [nTPM]":"32.4","Cell RNA - U-2197 [nTPM]":"37.8","Cell RNA - U-251 MG [nTPM]":"42.8","Cell RNA - U-266\/70 [nTPM]":"46.4","Cell RNA - U-266\/84 [nTPM]":"20.7","Cell RNA - U-698 [nTPM]":"23.3","Cell RNA - U-87 MG [nTPM]":"31.2","Cell RNA - U-937 [nTPM]":"63.4","Cell RNA - WM-115 [nTPM]":"37.4","Blood RNA - basophil [nTPM]":"23.9","Blood RNA - classical monocyte [nTPM]":"3.1","Blood RNA - eosinophil [nTPM]":"7.1","Blood RNA - gdT-cell [nTPM]":"3.4","Blood RNA - intermediate monocyte [nTPM]":"1.4","Blood RNA - MAIT T-cell [nTPM]":"3.2","Blood RNA - memory B-cell [nTPM]":"4.1","Blood RNA - memory CD4 T-cell [nTPM]":"3.0","Blood RNA - memory CD8 T-cell [nTPM]":"3.2","Blood RNA - myeloid DC [nTPM]":"0.9","Blood RNA - naive B-cell [nTPM]":"3.6","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.7","Blood RNA - neutrophil [nTPM]":"3.4","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"4.7","Blood RNA - plasmacytoid DC [nTPM]":"3.4","Blood RNA - T-reg [nTPM]":"4.5","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"2.1","Brain RNA - cerebellum [nTPM]":"2.6","Brain RNA - cerebral cortex [nTPM]":"4.0","Brain RNA - hippocampal formation [nTPM]":"2.8","Brain RNA - hypothalamus [nTPM]":"3.2","Brain RNA - medulla oblongata [nTPM]":"6.0","Brain RNA - midbrain [nTPM]":"4.3","Brain RNA - pons [nTPM]":"6.5","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"9.1","Brain RNA - white matter [nTPM]":"7.9","Single Cell Type RNA - Adipocytes [nTPM]":"6.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"54.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"35.4","Single Cell Type RNA - Astrocytes [nTPM]":"1.6","Single Cell Type RNA - B-cells [nTPM]":"27.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"41.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"52.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"61.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"54.7","Single Cell Type RNA - Bipolar cells [nTPM]":"2.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"175.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"94.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"28.6","Single Cell Type RNA - Club cells [nTPM]":"60.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.1","Single Cell Type RNA - dendritic cells [nTPM]":"39.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"18.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"39.7","Single Cell Type RNA - Early spermatids [nTPM]":"19.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"89.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"21.5","Single Cell Type RNA - Endothelial cells [nTPM]":"9.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"6.0","Single Cell Type RNA - Erythroid cells [nTPM]":"47.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"28.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"21.4","Single Cell Type RNA - Fibroblasts [nTPM]":"49.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"84.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"155.8","Single Cell Type RNA - granulocytes [nTPM]":"17.7","Single Cell Type RNA - Granulosa cells [nTPM]":"29.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"4.6","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"68.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.4","Single Cell Type RNA - Ionocytes [nTPM]":"28.5","Single Cell Type RNA - Kupffer cells [nTPM]":"77.0","Single Cell Type RNA - Langerhans cells [nTPM]":"122.5","Single Cell Type RNA - Late spermatids [nTPM]":"27.1","Single Cell Type RNA - Leydig cells [nTPM]":"4.7","Single Cell Type RNA - Macrophages [nTPM]":"84.4","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"195.8","Single Cell Type RNA - monocytes [nTPM]":"42.2","Single Cell Type RNA - Muller glia cells [nTPM]":"0.5","Single Cell Type RNA - NK-cells [nTPM]":"39.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"1.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"101.0","Single Cell Type RNA - Paneth cells [nTPM]":"15.8","Single Cell Type RNA - Peritubular cells [nTPM]":"4.5","Single Cell Type RNA - Plasma cells [nTPM]":"27.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"43.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"8.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"1.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"78.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"111.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"51.2","Single Cell Type RNA - Spermatocytes [nTPM]":"29.0","Single Cell Type RNA - Spermatogonia [nTPM]":"28.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"53.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.5","Single Cell Type RNA - T-cells [nTPM]":"41.6","Single Cell Type RNA - Theca cells [nTPM]":"2.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"17.0","Single Cell Type RNA - Urothelial cells [nTPM]":"75.3"},{"Gene":"SDHB","Gene synonym":["SDH","SDH1"],"Ensembl":"ENSG00000117118","Gene description":"Succinate dehydrogenase complex iron sulfur subunit B","Uniprot":["P21912"],"Chromosome":"1","Position":"17018722-17054032","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":["Oxidoreductase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"491.5","tongue":"580.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"405.5","Proximal tubular cells":"449.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002868","CAB009822","CAB068233","CAB068234","CAB068235"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Mitochondria"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"7900","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB009822":"AB_2183458","CAB068233":"AB_2665638","CAB068234":"AB_2665639","CAB068235":"AB_2665640","HPA002868":"AB_1079889"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.19e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.93e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.45e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.51e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.93e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.93e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.82e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-2"},"Tissue RNA - adipose tissue [nTPM]":"85.8","Tissue RNA - adrenal gland [nTPM]":"95.7","Tissue RNA - amygdala [nTPM]":"68.0","Tissue RNA - appendix [nTPM]":"59.0","Tissue RNA - basal ganglia [nTPM]":"72.2","Tissue RNA - bone marrow [nTPM]":"94.6","Tissue RNA - breast [nTPM]":"68.7","Tissue RNA - cerebellum [nTPM]":"80.6","Tissue RNA - cerebral cortex [nTPM]":"84.3","Tissue RNA - cervix [nTPM]":"56.8","Tissue RNA - choroid plexus [nTPM]":"81.1","Tissue RNA - colon [nTPM]":"134.3","Tissue RNA - duodenum [nTPM]":"163.0","Tissue RNA - endometrium 1 [nTPM]":"56.0","Tissue RNA - epididymis [nTPM]":"71.0","Tissue RNA - esophagus [nTPM]":"77.4","Tissue RNA - fallopian tube [nTPM]":"59.8","Tissue RNA - gallbladder [nTPM]":"48.0","Tissue RNA - heart muscle [nTPM]":"302.8","Tissue RNA - hippocampal formation [nTPM]":"69.9","Tissue RNA - hypothalamus [nTPM]":"76.9","Tissue RNA - kidney [nTPM]":"228.0","Tissue RNA - liver [nTPM]":"336.1","Tissue RNA - lung [nTPM]":"56.1","Tissue RNA - lymph node [nTPM]":"75.3","Tissue RNA - medulla oblongata [nTPM]":"74.8","Tissue RNA - midbrain [nTPM]":"71.4","Tissue RNA - ovary [nTPM]":"44.4","Tissue RNA - pancreas [nTPM]":"80.3","Tissue RNA - parathyroid gland [nTPM]":"144.3","Tissue RNA - pituitary gland [nTPM]":"42.8","Tissue RNA - placenta [nTPM]":"57.6","Tissue RNA - pons [nTPM]":"73.8","Tissue RNA - prostate [nTPM]":"55.7","Tissue RNA - rectum [nTPM]":"132.4","Tissue RNA - retina [nTPM]":"62.9","Tissue RNA - salivary gland [nTPM]":"74.0","Tissue RNA - seminal vesicle [nTPM]":"60.5","Tissue RNA - skeletal muscle [nTPM]":"491.5","Tissue RNA - skin 1 [nTPM]":"55.6","Tissue RNA - small intestine [nTPM]":"121.9","Tissue RNA - smooth muscle [nTPM]":"70.4","Tissue RNA - spinal cord [nTPM]":"73.9","Tissue RNA - spleen [nTPM]":"60.5","Tissue RNA - stomach 1 [nTPM]":"92.8","Tissue RNA - testis [nTPM]":"64.4","Tissue RNA - thalamus [nTPM]":"74.9","Tissue RNA - thymus [nTPM]":"62.7","Tissue RNA - thyroid gland [nTPM]":"64.3","Tissue RNA - tongue [nTPM]":"580.6","Tissue RNA - tonsil [nTPM]":"84.2","Tissue RNA - urinary bladder [nTPM]":"71.3","Tissue RNA - vagina [nTPM]":"52.0","Tissue RNA - white matter [nTPM]":"78.9","Cell RNA - A-431 [nTPM]":"157.3","Cell RNA - A549 [nTPM]":"152.7","Cell RNA - AF22 [nTPM]":"72.2","Cell RNA - AN3-CA [nTPM]":"107.8","Cell RNA - ASC diff [nTPM]":"141.6","Cell RNA - ASC TERT1 [nTPM]":"135.2","Cell RNA - BEWO [nTPM]":"95.9","Cell RNA - BJ [nTPM]":"122.4","Cell RNA - BJ hTERT+ [nTPM]":"145.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"254.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"227.7","Cell RNA - CACO-2 [nTPM]":"216.8","Cell RNA - CAPAN-2 [nTPM]":"183.1","Cell RNA - Daudi [nTPM]":"206.8","Cell RNA - EFO-21 [nTPM]":"159.3","Cell RNA - fHDF\/TERT166 [nTPM]":"156.4","Cell RNA - GAMG [nTPM]":"176.1","Cell RNA - HaCaT [nTPM]":"180.1","Cell RNA - HAP1 [nTPM]":"290.7","Cell RNA - HBEC3-KT [nTPM]":"226.8","Cell RNA - HBF TERT88 [nTPM]":"284.8","Cell RNA - HDLM-2 [nTPM]":"128.7","Cell RNA - HEK 293 [nTPM]":"280.6","Cell RNA - HEL [nTPM]":"183.4","Cell RNA - HeLa [nTPM]":"149.2","Cell RNA - Hep G2 [nTPM]":"168.2","Cell RNA - HHSteC [nTPM]":"172.8","Cell RNA - HL-60 [nTPM]":"276.0","Cell RNA - HMC-1 [nTPM]":"135.6","Cell RNA - HSkMC [nTPM]":"140.4","Cell RNA - hTCEpi [nTPM]":"154.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"224.5","Cell RNA - hTERT-HME1 [nTPM]":"370.1","Cell RNA - hTERT-RPE1 [nTPM]":"138.7","Cell RNA - HUVEC TERT2 [nTPM]":"183.6","Cell RNA - JURKAT [nTPM]":"176.5","Cell RNA - K-562 [nTPM]":"165.2","Cell RNA - Karpas-707 [nTPM]":"236.9","Cell RNA - LHCN-M2 [nTPM]":"179.6","Cell RNA - MCF7 [nTPM]":"129.5","Cell RNA - MOLT-4 [nTPM]":"182.4","Cell RNA - NB-4 [nTPM]":"175.1","Cell RNA - NTERA-2 [nTPM]":"70.4","Cell RNA - OE19 [nTPM]":"224.6","Cell RNA - PC-3 [nTPM]":"302.6","Cell RNA - REH [nTPM]":"146.1","Cell RNA - RH-30 [nTPM]":"142.5","Cell RNA - RPMI-8226 [nTPM]":"265.4","Cell RNA - RPTEC TERT1 [nTPM]":"252.4","Cell RNA - RT4 [nTPM]":"88.7","Cell RNA - SCLC-21H [nTPM]":"157.5","Cell RNA - SH-SY5Y [nTPM]":"86.0","Cell RNA - SiHa [nTPM]":"172.3","Cell RNA - SK-BR-3 [nTPM]":"216.3","Cell RNA - SK-MEL-30 [nTPM]":"392.3","Cell RNA - SuSa [nTPM]":"76.4","Cell RNA - T-47d [nTPM]":"131.1","Cell RNA - THP-1 [nTPM]":"169.1","Cell RNA - TIME [nTPM]":"94.9","Cell RNA - U-138 MG [nTPM]":"115.8","Cell RNA - U-2 OS [nTPM]":"131.0","Cell RNA - U-2197 [nTPM]":"206.4","Cell RNA - U-251 MG [nTPM]":"176.0","Cell RNA - U-266\/70 [nTPM]":"98.9","Cell RNA - U-266\/84 [nTPM]":"133.3","Cell RNA - U-698 [nTPM]":"198.6","Cell RNA - U-87 MG [nTPM]":"170.4","Cell RNA - U-937 [nTPM]":"438.5","Cell RNA - WM-115 [nTPM]":"128.3","Blood RNA - basophil [nTPM]":"68.7","Blood RNA - classical monocyte [nTPM]":"149.8","Blood RNA - eosinophil [nTPM]":"149.5","Blood RNA - gdT-cell [nTPM]":"71.4","Blood RNA - intermediate monocyte [nTPM]":"206.5","Blood RNA - MAIT T-cell [nTPM]":"70.7","Blood RNA - memory B-cell [nTPM]":"89.9","Blood RNA - memory CD4 T-cell [nTPM]":"81.0","Blood RNA - memory CD8 T-cell [nTPM]":"77.5","Blood RNA - myeloid DC [nTPM]":"186.8","Blood RNA - naive B-cell [nTPM]":"81.1","Blood RNA - naive CD4 T-cell [nTPM]":"73.5","Blood RNA - naive CD8 T-cell [nTPM]":"74.8","Blood RNA - neutrophil [nTPM]":"174.3","Blood RNA - NK-cell [nTPM]":"85.3","Blood RNA - non-classical monocyte [nTPM]":"185.7","Blood RNA - plasmacytoid DC [nTPM]":"89.3","Blood RNA - T-reg [nTPM]":"113.8","Blood RNA - total PBMC [nTPM]":"116.1","Brain RNA - amygdala [nTPM]":"68.0","Brain RNA - basal ganglia [nTPM]":"72.2","Brain RNA - cerebellum [nTPM]":"80.6","Brain RNA - cerebral cortex [nTPM]":"84.3","Brain RNA - hippocampal formation [nTPM]":"69.9","Brain RNA - hypothalamus [nTPM]":"76.9","Brain RNA - medulla oblongata [nTPM]":"74.8","Brain RNA - midbrain [nTPM]":"71.4","Brain RNA - pons [nTPM]":"73.8","Brain RNA - spinal cord [nTPM]":"73.9","Brain RNA - thalamus [nTPM]":"74.9","Brain RNA - white matter [nTPM]":"78.9","Single Cell Type RNA - Adipocytes [nTPM]":"48.2","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"64.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"47.4","Single Cell Type RNA - Astrocytes [nTPM]":"20.9","Single Cell Type RNA - B-cells [nTPM]":"57.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"52.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"93.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"199.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"40.5","Single Cell Type RNA - Bipolar cells [nTPM]":"31.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"45.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"405.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"101.5","Single Cell Type RNA - Club cells [nTPM]":"97.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"107.1","Single Cell Type RNA - dendritic cells [nTPM]":"48.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"176.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"354.1","Single Cell Type RNA - Ductal cells [nTPM]":"134.3","Single Cell Type RNA - Early spermatids [nTPM]":"220.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"48.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.2","Single Cell Type RNA - Endothelial cells [nTPM]":"54.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"48.6","Single Cell Type RNA - Erythroid cells [nTPM]":"77.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"27.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"149.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"142.2","Single Cell Type RNA - Fibroblasts [nTPM]":"62.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"46.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"45.5","Single Cell Type RNA - granulocytes [nTPM]":"66.6","Single Cell Type RNA - Granulosa cells [nTPM]":"39.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"46.8","Single Cell Type RNA - Hepatocytes [nTPM]":"226.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"177.4","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"32.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.1","Single Cell Type RNA - Ionocytes [nTPM]":"116.0","Single Cell Type RNA - Kupffer cells [nTPM]":"88.7","Single Cell Type RNA - Langerhans cells [nTPM]":"67.9","Single Cell Type RNA - Late spermatids [nTPM]":"30.5","Single Cell Type RNA - Leydig cells [nTPM]":"57.8","Single Cell Type RNA - Macrophages [nTPM]":"78.4","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"123.1","Single Cell Type RNA - Muller glia cells [nTPM]":"78.3","Single Cell Type RNA - NK-cells [nTPM]":"48.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"15.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"111.5","Single Cell Type RNA - Paneth cells [nTPM]":"218.3","Single Cell Type RNA - Peritubular cells [nTPM]":"67.7","Single Cell Type RNA - Plasma cells [nTPM]":"62.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"300.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"449.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"79.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"53.8","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"57.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"191.6","Single Cell Type RNA - Spermatocytes [nTPM]":"148.9","Single Cell Type RNA - Spermatogonia [nTPM]":"71.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"72.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"54.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"121.8","Single Cell Type RNA - T-cells [nTPM]":"46.8","Single Cell Type RNA - Theca cells [nTPM]":"69.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"162.0","Single Cell Type RNA - Urothelial cells [nTPM]":"110.9"},{"Gene":"SDHC","Gene synonym":["CYB560","cybL","PGL3"],"Ensembl":"ENSG00000143252","Gene description":"Succinate dehydrogenase complex subunit C","Uniprot":["Q99643"],"Chromosome":"1","Position":"161314381-161363206","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"776.7","Proximal tubular cells":"916.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Non-specific - Transcription","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 43: THP-1 - Innate immune response","Single cell expression cluster":"Cluster 67: Proximal tubular cells - Tubular reabsorption","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.38e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.90e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.02e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.38e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.29e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.20e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.19e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.77e-1"},"Tissue RNA - adipose tissue [nTPM]":"128.9","Tissue RNA - adrenal gland [nTPM]":"143.7","Tissue RNA - amygdala [nTPM]":"73.7","Tissue RNA - appendix [nTPM]":"64.1","Tissue RNA - basal ganglia [nTPM]":"79.7","Tissue RNA - bone marrow [nTPM]":"60.5","Tissue RNA - breast [nTPM]":"100.3","Tissue RNA - cerebellum [nTPM]":"84.5","Tissue RNA - cerebral cortex [nTPM]":"85.1","Tissue RNA - cervix [nTPM]":"78.7","Tissue RNA - choroid plexus [nTPM]":"92.9","Tissue RNA - colon [nTPM]":"118.9","Tissue RNA - duodenum [nTPM]":"127.8","Tissue RNA - endometrium 1 [nTPM]":"70.9","Tissue RNA - epididymis [nTPM]":"76.0","Tissue RNA - esophagus [nTPM]":"109.7","Tissue RNA - fallopian tube [nTPM]":"98.6","Tissue RNA - gallbladder [nTPM]":"63.3","Tissue RNA - heart muscle [nTPM]":"154.1","Tissue RNA - hippocampal formation [nTPM]":"68.4","Tissue RNA - hypothalamus [nTPM]":"83.4","Tissue RNA - kidney [nTPM]":"285.7","Tissue RNA - liver [nTPM]":"319.4","Tissue RNA - lung [nTPM]":"65.5","Tissue RNA - lymph node [nTPM]":"74.7","Tissue RNA - medulla oblongata [nTPM]":"78.8","Tissue RNA - midbrain [nTPM]":"79.1","Tissue RNA - ovary [nTPM]":"69.2","Tissue RNA - pancreas [nTPM]":"62.5","Tissue RNA - parathyroid gland [nTPM]":"173.6","Tissue RNA - pituitary gland [nTPM]":"52.4","Tissue RNA - placenta [nTPM]":"73.1","Tissue RNA - pons [nTPM]":"76.7","Tissue RNA - prostate [nTPM]":"77.3","Tissue RNA - rectum [nTPM]":"132.2","Tissue RNA - retina [nTPM]":"84.3","Tissue RNA - salivary gland [nTPM]":"74.8","Tissue RNA - seminal vesicle [nTPM]":"84.7","Tissue RNA - skeletal muscle [nTPM]":"277.4","Tissue RNA - skin 1 [nTPM]":"69.8","Tissue RNA - small intestine [nTPM]":"101.4","Tissue RNA - smooth muscle [nTPM]":"101.4","Tissue RNA - spinal cord [nTPM]":"85.1","Tissue RNA - spleen [nTPM]":"62.8","Tissue RNA - stomach 1 [nTPM]":"89.9","Tissue RNA - testis [nTPM]":"52.7","Tissue RNA - thalamus [nTPM]":"84.8","Tissue RNA - thymus [nTPM]":"93.1","Tissue RNA - thyroid gland [nTPM]":"89.5","Tissue RNA - tongue [nTPM]":"288.4","Tissue RNA - tonsil [nTPM]":"105.1","Tissue RNA - urinary bladder [nTPM]":"88.4","Tissue RNA - vagina [nTPM]":"61.3","Tissue RNA - white matter [nTPM]":"85.6","Cell RNA - A-431 [nTPM]":"161.1","Cell RNA - A549 [nTPM]":"129.7","Cell RNA - AF22 [nTPM]":"157.5","Cell RNA - AN3-CA [nTPM]":"147.7","Cell RNA - ASC diff [nTPM]":"248.3","Cell RNA - ASC TERT1 [nTPM]":"213.3","Cell RNA - BEWO [nTPM]":"196.3","Cell RNA - BJ [nTPM]":"150.9","Cell RNA - BJ hTERT+ [nTPM]":"190.3","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"180.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"137.3","Cell RNA - CACO-2 [nTPM]":"185.4","Cell RNA - CAPAN-2 [nTPM]":"208.7","Cell RNA - Daudi [nTPM]":"53.7","Cell RNA - EFO-21 [nTPM]":"190.6","Cell RNA - fHDF\/TERT166 [nTPM]":"214.8","Cell RNA - GAMG [nTPM]":"121.6","Cell RNA - HaCaT [nTPM]":"178.5","Cell RNA - HAP1 [nTPM]":"244.3","Cell RNA - HBEC3-KT [nTPM]":"214.2","Cell RNA - HBF TERT88 [nTPM]":"193.2","Cell RNA - HDLM-2 [nTPM]":"185.6","Cell RNA - HEK 293 [nTPM]":"205.6","Cell RNA - HEL [nTPM]":"110.2","Cell RNA - HeLa [nTPM]":"106.6","Cell RNA - Hep G2 [nTPM]":"196.7","Cell RNA - HHSteC [nTPM]":"126.9","Cell RNA - HL-60 [nTPM]":"193.8","Cell RNA - HMC-1 [nTPM]":"109.1","Cell RNA - HSkMC [nTPM]":"211.5","Cell RNA - hTCEpi [nTPM]":"181.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"174.3","Cell RNA - hTERT-HME1 [nTPM]":"119.4","Cell RNA - hTERT-RPE1 [nTPM]":"167.9","Cell RNA - HUVEC TERT2 [nTPM]":"177.5","Cell RNA - JURKAT [nTPM]":"164.0","Cell RNA - K-562 [nTPM]":"178.9","Cell RNA - Karpas-707 [nTPM]":"43.8","Cell RNA - LHCN-M2 [nTPM]":"266.3","Cell RNA - MCF7 [nTPM]":"167.0","Cell RNA - MOLT-4 [nTPM]":"152.4","Cell RNA - NB-4 [nTPM]":"112.5","Cell RNA - NTERA-2 [nTPM]":"145.4","Cell RNA - OE19 [nTPM]":"376.3","Cell RNA - PC-3 [nTPM]":"123.7","Cell RNA - REH [nTPM]":"131.6","Cell RNA - RH-30 [nTPM]":"151.0","Cell RNA - RPMI-8226 [nTPM]":"217.1","Cell RNA - RPTEC TERT1 [nTPM]":"330.3","Cell RNA - RT4 [nTPM]":"167.8","Cell RNA - SCLC-21H [nTPM]":"118.3","Cell RNA - SH-SY5Y [nTPM]":"180.7","Cell RNA - SiHa [nTPM]":"211.0","Cell RNA - SK-BR-3 [nTPM]":"385.1","Cell RNA - SK-MEL-30 [nTPM]":"225.4","Cell RNA - SuSa [nTPM]":"207.9","Cell RNA - T-47d [nTPM]":"342.1","Cell RNA - THP-1 [nTPM]":"259.3","Cell RNA - TIME [nTPM]":"133.5","Cell RNA - U-138 MG [nTPM]":"103.7","Cell RNA - U-2 OS [nTPM]":"125.1","Cell RNA - U-2197 [nTPM]":"127.9","Cell RNA - U-251 MG [nTPM]":"147.3","Cell RNA - U-266\/70 [nTPM]":"173.3","Cell RNA - U-266\/84 [nTPM]":"287.8","Cell RNA - U-698 [nTPM]":"269.4","Cell RNA - U-87 MG [nTPM]":"140.3","Cell RNA - U-937 [nTPM]":"139.2","Cell RNA - WM-115 [nTPM]":"193.6","Blood RNA - basophil [nTPM]":"88.6","Blood RNA - classical monocyte [nTPM]":"111.0","Blood RNA - eosinophil [nTPM]":"65.7","Blood RNA - gdT-cell [nTPM]":"76.6","Blood RNA - intermediate monocyte [nTPM]":"99.6","Blood RNA - MAIT T-cell [nTPM]":"79.6","Blood RNA - memory B-cell [nTPM]":"68.6","Blood RNA - memory CD4 T-cell [nTPM]":"66.2","Blood RNA - memory CD8 T-cell [nTPM]":"75.4","Blood RNA - myeloid DC [nTPM]":"136.1","Blood RNA - naive B-cell [nTPM]":"65.7","Blood RNA - naive CD4 T-cell [nTPM]":"71.2","Blood RNA - naive CD8 T-cell [nTPM]":"71.0","Blood RNA - neutrophil [nTPM]":"52.0","Blood RNA - NK-cell [nTPM]":"66.9","Blood RNA - non-classical monocyte [nTPM]":"87.5","Blood RNA - plasmacytoid DC [nTPM]":"100.6","Blood RNA - T-reg [nTPM]":"78.3","Blood RNA - total PBMC [nTPM]":"130.0","Brain RNA - amygdala [nTPM]":"73.7","Brain RNA - basal ganglia [nTPM]":"79.7","Brain RNA - cerebellum [nTPM]":"84.5","Brain RNA - cerebral cortex [nTPM]":"85.1","Brain RNA - hippocampal formation [nTPM]":"68.4","Brain RNA - hypothalamus [nTPM]":"83.4","Brain RNA - medulla oblongata [nTPM]":"78.8","Brain RNA - midbrain [nTPM]":"79.1","Brain RNA - pons [nTPM]":"76.7","Brain RNA - spinal cord [nTPM]":"85.1","Brain RNA - thalamus [nTPM]":"84.8","Brain RNA - white matter [nTPM]":"85.6","Single Cell Type RNA - Adipocytes [nTPM]":"50.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"59.4","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"70.1","Single Cell Type RNA - Basal keratinocytes [nTPM]":"61.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"151.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"342.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"59.7","Single Cell Type RNA - Bipolar cells [nTPM]":"74.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"81.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"58.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"94.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"131.5","Single Cell Type RNA - Club cells [nTPM]":"163.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"150.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"64.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"248.0","Single Cell Type RNA - dendritic cells [nTPM]":"65.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"95.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"776.7","Single Cell Type RNA - Ductal cells [nTPM]":"218.4","Single Cell Type RNA - Early spermatids [nTPM]":"18.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"87.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"63.8","Single Cell Type RNA - Endothelial cells [nTPM]":"80.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"66.8","Single Cell Type RNA - Erythroid cells [nTPM]":"81.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"19.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"145.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"248.5","Single Cell Type RNA - Fibroblasts [nTPM]":"79.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"79.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"62.6","Single Cell Type RNA - granulocytes [nTPM]":"58.3","Single Cell Type RNA - Granulosa cells [nTPM]":"66.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"83.2","Single Cell Type RNA - Hepatocytes [nTPM]":"249.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"237.3","Single Cell Type RNA - Horizontal cells [nTPM]":"72.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"27.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"103.4","Single Cell Type RNA - Ionocytes [nTPM]":"215.7","Single Cell Type RNA - Kupffer cells [nTPM]":"100.6","Single Cell Type RNA - Langerhans cells [nTPM]":"74.4","Single Cell Type RNA - Late spermatids [nTPM]":"34.7","Single Cell Type RNA - Leydig cells [nTPM]":"102.9","Single Cell Type RNA - Macrophages [nTPM]":"94.6","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"176.1","Single Cell Type RNA - Muller glia cells [nTPM]":"107.8","Single Cell Type RNA - NK-cells [nTPM]":"107.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"24.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"142.7","Single Cell Type RNA - Paneth cells [nTPM]":"89.5","Single Cell Type RNA - Peritubular cells [nTPM]":"109.1","Single Cell Type RNA - Plasma cells [nTPM]":"71.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"100.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"139.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"916.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"177.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"69.3","Single Cell Type RNA - Sertoli cells [nTPM]":"52.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"74.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.4","Single Cell Type RNA - Spermatocytes [nTPM]":"115.3","Single Cell Type RNA - Spermatogonia [nTPM]":"114.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"111.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"76.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"307.6","Single Cell Type RNA - T-cells [nTPM]":"72.0","Single Cell Type RNA - Theca cells [nTPM]":"215.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"154.2","Single Cell Type RNA - Urothelial cells [nTPM]":"155.0"},{"Gene":"SDHD","Gene synonym":["cybS","PGL","PGL1"],"Ensembl":"ENSG00000204370","Gene description":"Succinate dehydrogenase complex subunit D","Uniprot":["O14521"],"Chromosome":"11","Position":"112086824-112120016","Protein class":["Cancer-related genes","Citric acid cycle related proteins","Disease related genes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Electron transport","Transport","Tricarboxylic acid cycle"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets","Primary mitochondrial disease"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal tubular cells":"530.2","Proximal tubular cells":"449.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045727"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 8: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 39: Non-specific - Basic cellular processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA045727":"AB_10963114"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.13e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.51e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.47e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.21e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.98e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.83e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.10e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.99e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.56e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.51e-2"},"Tissue RNA - adipose tissue [nTPM]":"117.5","Tissue RNA - adrenal gland [nTPM]":"95.7","Tissue RNA - amygdala [nTPM]":"60.0","Tissue RNA - appendix [nTPM]":"84.5","Tissue RNA - basal ganglia [nTPM]":"63.1","Tissue RNA - bone marrow [nTPM]":"72.9","Tissue RNA - breast [nTPM]":"102.6","Tissue RNA - cerebellum [nTPM]":"68.6","Tissue RNA - cerebral cortex [nTPM]":"76.3","Tissue RNA - cervix [nTPM]":"92.5","Tissue RNA - choroid plexus [nTPM]":"65.1","Tissue RNA - colon [nTPM]":"185.2","Tissue RNA - duodenum [nTPM]":"208.1","Tissue RNA - endometrium 1 [nTPM]":"88.2","Tissue RNA - epididymis [nTPM]":"96.7","Tissue RNA - esophagus [nTPM]":"126.7","Tissue RNA - fallopian tube [nTPM]":"92.6","Tissue RNA - gallbladder [nTPM]":"85.6","Tissue RNA - heart muscle [nTPM]":"254.7","Tissue RNA - hippocampal formation [nTPM]":"60.1","Tissue RNA - hypothalamus [nTPM]":"65.4","Tissue RNA - kidney [nTPM]":"319.9","Tissue RNA - liver [nTPM]":"391.8","Tissue RNA - lung [nTPM]":"79.3","Tissue RNA - lymph node [nTPM]":"131.7","Tissue RNA - medulla oblongata [nTPM]":"63.4","Tissue RNA - midbrain [nTPM]":"62.5","Tissue RNA - ovary [nTPM]":"91.6","Tissue RNA - pancreas [nTPM]":"77.8","Tissue RNA - parathyroid gland [nTPM]":"152.4","Tissue RNA - pituitary gland [nTPM]":"37.0","Tissue RNA - placenta [nTPM]":"95.0","Tissue RNA - pons [nTPM]":"63.2","Tissue RNA - prostate [nTPM]":"87.9","Tissue RNA - rectum [nTPM]":"190.8","Tissue RNA - retina [nTPM]":"37.4","Tissue RNA - salivary gland [nTPM]":"112.6","Tissue RNA - seminal vesicle [nTPM]":"100.9","Tissue RNA - skeletal muscle [nTPM]":"354.7","Tissue RNA - skin 1 [nTPM]":"64.3","Tissue RNA - small intestine [nTPM]":"175.6","Tissue RNA - smooth muscle [nTPM]":"98.1","Tissue RNA - spinal cord [nTPM]":"64.7","Tissue RNA - spleen [nTPM]":"85.1","Tissue RNA - stomach 1 [nTPM]":"101.1","Tissue RNA - testis [nTPM]":"34.1","Tissue RNA - thalamus [nTPM]":"63.7","Tissue RNA - thymus [nTPM]":"102.5","Tissue RNA - thyroid gland [nTPM]":"136.8","Tissue RNA - tongue [nTPM]":"449.6","Tissue RNA - tonsil [nTPM]":"124.8","Tissue RNA - urinary bladder [nTPM]":"117.9","Tissue RNA - vagina [nTPM]":"76.4","Tissue RNA - white matter [nTPM]":"68.2","Cell RNA - A-431 [nTPM]":"84.0","Cell RNA - A549 [nTPM]":"67.3","Cell RNA - AF22 [nTPM]":"58.1","Cell RNA - AN3-CA [nTPM]":"89.4","Cell RNA - ASC diff [nTPM]":"212.0","Cell RNA - ASC TERT1 [nTPM]":"170.7","Cell RNA - BEWO [nTPM]":"97.3","Cell RNA - BJ [nTPM]":"97.5","Cell RNA - BJ hTERT+ [nTPM]":"147.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"106.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"132.2","Cell RNA - CACO-2 [nTPM]":"244.8","Cell RNA - CAPAN-2 [nTPM]":"222.1","Cell RNA - Daudi [nTPM]":"155.5","Cell RNA - EFO-21 [nTPM]":"288.4","Cell RNA - fHDF\/TERT166 [nTPM]":"131.0","Cell RNA - GAMG [nTPM]":"156.1","Cell RNA - HaCaT [nTPM]":"203.5","Cell RNA - HAP1 [nTPM]":"175.4","Cell RNA - HBEC3-KT [nTPM]":"139.8","Cell RNA - HBF TERT88 [nTPM]":"129.8","Cell RNA - HDLM-2 [nTPM]":"129.9","Cell RNA - HEK 293 [nTPM]":"92.4","Cell RNA - HEL [nTPM]":"142.8","Cell RNA - HeLa [nTPM]":"51.9","Cell RNA - Hep G2 [nTPM]":"140.1","Cell RNA - HHSteC [nTPM]":"165.6","Cell RNA - HL-60 [nTPM]":"222.4","Cell RNA - HMC-1 [nTPM]":"107.5","Cell RNA - HSkMC [nTPM]":"189.6","Cell RNA - hTCEpi [nTPM]":"160.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"110.5","Cell RNA - hTERT-HME1 [nTPM]":"189.1","Cell RNA - hTERT-RPE1 [nTPM]":"124.6","Cell RNA - HUVEC TERT2 [nTPM]":"153.0","Cell RNA - JURKAT [nTPM]":"109.6","Cell RNA - K-562 [nTPM]":"156.0","Cell RNA - Karpas-707 [nTPM]":"208.7","Cell RNA - LHCN-M2 [nTPM]":"135.0","Cell RNA - MCF7 [nTPM]":"95.2","Cell RNA - MOLT-4 [nTPM]":"143.9","Cell RNA - NB-4 [nTPM]":"215.0","Cell RNA - NTERA-2 [nTPM]":"77.4","Cell RNA - OE19 [nTPM]":"333.8","Cell RNA - PC-3 [nTPM]":"211.6","Cell RNA - REH [nTPM]":"126.2","Cell RNA - RH-30 [nTPM]":"145.8","Cell RNA - RPMI-8226 [nTPM]":"294.4","Cell RNA - RPTEC TERT1 [nTPM]":"221.6","Cell RNA - RT4 [nTPM]":"175.2","Cell RNA - SCLC-21H [nTPM]":"83.5","Cell RNA - SH-SY5Y [nTPM]":"55.8","Cell RNA - SiHa [nTPM]":"135.3","Cell RNA - SK-BR-3 [nTPM]":"194.8","Cell RNA - SK-MEL-30 [nTPM]":"107.0","Cell RNA - SuSa [nTPM]":"81.8","Cell RNA - T-47d [nTPM]":"198.9","Cell RNA - THP-1 [nTPM]":"164.2","Cell RNA - TIME [nTPM]":"108.0","Cell RNA - U-138 MG [nTPM]":"103.8","Cell RNA - U-2 OS [nTPM]":"132.3","Cell RNA - U-2197 [nTPM]":"114.7","Cell RNA - U-251 MG [nTPM]":"95.0","Cell RNA - U-266\/70 [nTPM]":"59.1","Cell RNA - U-266\/84 [nTPM]":"73.2","Cell RNA - U-698 [nTPM]":"270.7","Cell RNA - U-87 MG [nTPM]":"58.8","Cell RNA - U-937 [nTPM]":"297.0","Cell RNA - WM-115 [nTPM]":"100.5","Blood RNA - basophil [nTPM]":"233.7","Blood RNA - classical monocyte [nTPM]":"293.3","Blood RNA - eosinophil [nTPM]":"208.8","Blood RNA - gdT-cell [nTPM]":"158.4","Blood RNA - intermediate monocyte [nTPM]":"390.1","Blood RNA - MAIT T-cell [nTPM]":"173.1","Blood RNA - memory B-cell [nTPM]":"235.2","Blood RNA - memory CD4 T-cell [nTPM]":"170.8","Blood RNA - memory CD8 T-cell [nTPM]":"168.8","Blood RNA - myeloid DC [nTPM]":"308.7","Blood RNA - naive B-cell [nTPM]":"198.1","Blood RNA - naive CD4 T-cell [nTPM]":"204.3","Blood RNA - naive CD8 T-cell [nTPM]":"191.8","Blood RNA - neutrophil [nTPM]":"257.5","Blood RNA - NK-cell [nTPM]":"207.9","Blood RNA - non-classical monocyte [nTPM]":"322.9","Blood RNA - plasmacytoid DC [nTPM]":"151.7","Blood RNA - T-reg [nTPM]":"189.9","Blood RNA - total PBMC [nTPM]":"348.9","Brain RNA - amygdala [nTPM]":"60.0","Brain RNA - basal ganglia [nTPM]":"63.1","Brain RNA - cerebellum [nTPM]":"68.6","Brain RNA - cerebral cortex [nTPM]":"76.3","Brain RNA - hippocampal formation [nTPM]":"60.1","Brain RNA - hypothalamus [nTPM]":"65.4","Brain RNA - medulla oblongata [nTPM]":"63.4","Brain RNA - midbrain [nTPM]":"62.5","Brain RNA - pons [nTPM]":"63.2","Brain RNA - spinal cord [nTPM]":"64.7","Brain RNA - thalamus [nTPM]":"63.7","Brain RNA - white matter [nTPM]":"68.2","Single Cell Type RNA - Adipocytes [nTPM]":"104.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"80.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"51.1","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"78.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"81.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"102.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"262.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"83.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"61.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"78.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"216.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"120.1","Single Cell Type RNA - Club cells [nTPM]":"108.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"90.1","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"154.3","Single Cell Type RNA - dendritic cells [nTPM]":"55.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"203.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"530.2","Single Cell Type RNA - Ductal cells [nTPM]":"82.9","Single Cell Type RNA - Early spermatids [nTPM]":"9.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"41.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"67.6","Single Cell Type RNA - Endothelial cells [nTPM]":"76.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"50.4","Single Cell Type RNA - Erythroid cells [nTPM]":"70.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.6","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"58.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"124.1","Single Cell Type RNA - Fibroblasts [nTPM]":"104.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"75.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.2","Single Cell Type RNA - granulocytes [nTPM]":"65.9","Single Cell Type RNA - Granulosa cells [nTPM]":"32.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"76.8","Single Cell Type RNA - Hepatocytes [nTPM]":"169.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"162.9","Single Cell Type RNA - Horizontal cells [nTPM]":"11.8","Single Cell Type RNA - Inhibitory neurons [nTPM]":"11.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"129.1","Single Cell Type RNA - Ionocytes [nTPM]":"154.6","Single Cell Type RNA - Kupffer cells [nTPM]":"97.1","Single Cell Type RNA - Langerhans cells [nTPM]":"74.4","Single Cell Type RNA - Late spermatids [nTPM]":"37.0","Single Cell Type RNA - Leydig cells [nTPM]":"104.1","Single Cell Type RNA - Macrophages [nTPM]":"94.2","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"9.4","Single Cell Type RNA - monocytes [nTPM]":"118.6","Single Cell Type RNA - Muller glia cells [nTPM]":"52.9","Single Cell Type RNA - NK-cells [nTPM]":"75.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"9.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"54.1","Single Cell Type RNA - Paneth cells [nTPM]":"134.2","Single Cell Type RNA - Peritubular cells [nTPM]":"99.6","Single Cell Type RNA - Plasma cells [nTPM]":"80.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"61.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"253.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"449.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"60.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.9","Single Cell Type RNA - Sertoli cells [nTPM]":"92.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"78.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"110.7","Single Cell Type RNA - Spermatocytes [nTPM]":"70.4","Single Cell Type RNA - Spermatogonia [nTPM]":"55.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"127.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"74.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"179.0","Single Cell Type RNA - T-cells [nTPM]":"71.4","Single Cell Type RNA - Theca cells [nTPM]":"86.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"176.0","Single Cell Type RNA - Urothelial cells [nTPM]":"98.6"},{"Gene":"SETBP1","Gene synonym":["KIAA0437","SEB"],"Ensembl":"ENSG00000152217","Gene description":"SET binding protein 1","Uniprot":["Q9Y6X0"],"Chromosome":"18","Position":"44680173-45068510","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Excitatory neurons":"349.0","Inhibitory neurons":"548.3","Oligodendrocyte precursor cells":"170.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"cerebellum":"11.6"},"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"naive B-cell":"3.0","plasmacytoid DC":"2.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"3.0","dendritic cells":"2.8","monocytes":"1.0"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"16.1","Karpas-707":"44.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049022","HPA057259"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"66000","Blood expression cluster":"Cluster 19: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 46: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 8: Neurons & Oligodendrocytes - Synaptic function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Cytosol"],"Antibody RRID":{"HPA049022":"AB_2680602","HPA057259":"AB_2683384"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.80e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.49e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.01e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.71e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.52e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.34e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.18e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.29e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.81e-5"},"Tissue RNA - adipose tissue [nTPM]":"7.3","Tissue RNA - adrenal gland [nTPM]":"1.9","Tissue RNA - amygdala [nTPM]":"2.0","Tissue RNA - appendix [nTPM]":"3.7","Tissue RNA - basal ganglia [nTPM]":"3.7","Tissue RNA - bone marrow [nTPM]":"1.8","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"11.6","Tissue RNA - cerebral cortex [nTPM]":"5.7","Tissue RNA - cervix [nTPM]":"11.6","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"10.9","Tissue RNA - duodenum [nTPM]":"1.7","Tissue RNA - endometrium 1 [nTPM]":"8.3","Tissue RNA - epididymis [nTPM]":"7.2","Tissue RNA - esophagus [nTPM]":"4.5","Tissue RNA - fallopian tube [nTPM]":"7.2","Tissue RNA - gallbladder [nTPM]":"5.0","Tissue RNA - heart muscle [nTPM]":"4.3","Tissue RNA - hippocampal formation [nTPM]":"2.6","Tissue RNA - hypothalamus [nTPM]":"0.2","Tissue RNA - kidney [nTPM]":"7.4","Tissue RNA - liver [nTPM]":"4.7","Tissue RNA - lung [nTPM]":"6.6","Tissue RNA - lymph node [nTPM]":"5.3","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"7.7","Tissue RNA - pancreas [nTPM]":"5.8","Tissue RNA - parathyroid gland [nTPM]":"3.7","Tissue RNA - pituitary gland [nTPM]":"2.7","Tissue RNA - placenta [nTPM]":"7.2","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"7.8","Tissue RNA - rectum [nTPM]":"3.5","Tissue RNA - retina [nTPM]":"3.0","Tissue RNA - salivary gland [nTPM]":"4.3","Tissue RNA - seminal vesicle [nTPM]":"9.2","Tissue RNA - skeletal muscle [nTPM]":"10.7","Tissue RNA - skin 1 [nTPM]":"4.4","Tissue RNA - small intestine [nTPM]":"4.6","Tissue RNA - smooth muscle [nTPM]":"7.4","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"3.7","Tissue RNA - stomach 1 [nTPM]":"5.6","Tissue RNA - testis [nTPM]":"1.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"5.1","Tissue RNA - tongue [nTPM]":"9.7","Tissue RNA - tonsil [nTPM]":"4.7","Tissue RNA - urinary bladder [nTPM]":"8.1","Tissue RNA - vagina [nTPM]":"8.5","Tissue RNA - white matter [nTPM]":"3.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"2.4","Cell RNA - AF22 [nTPM]":"16.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"4.1","Cell RNA - ASC TERT1 [nTPM]":"1.2","Cell RNA - BEWO [nTPM]":"1.0","Cell RNA - BJ [nTPM]":"1.3","Cell RNA - BJ hTERT+ [nTPM]":"3.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"1.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"1.3","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"1.0","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"1.8","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"4.8","Cell RNA - HAP1 [nTPM]":"1.8","Cell RNA - HBEC3-KT [nTPM]":"4.9","Cell RNA - HBF TERT88 [nTPM]":"1.0","Cell RNA - HDLM-2 [nTPM]":"1.4","Cell RNA - HEK 293 [nTPM]":"0.8","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"2.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"3.0","Cell RNA - hTERT-RPE1 [nTPM]":"2.7","Cell RNA - HUVEC TERT2 [nTPM]":"0.5","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"44.7","Cell RNA - LHCN-M2 [nTPM]":"0.4","Cell RNA - MCF7 [nTPM]":"0.8","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"2.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"1.1","Cell RNA - REH [nTPM]":"5.6","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"5.5","Cell RNA - RPTEC TERT1 [nTPM]":"4.9","Cell RNA - RT4 [nTPM]":"3.9","Cell RNA - SCLC-21H [nTPM]":"8.2","Cell RNA - SH-SY5Y [nTPM]":"4.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.9","Cell RNA - SuSa [nTPM]":"7.1","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"9.5","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"7.7","Cell RNA - U-266\/70 [nTPM]":"8.6","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"5.8","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"5.5","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"0.6","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"2.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.2","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"3.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.1","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"1.0","Blood RNA - plasmacytoid DC [nTPM]":"2.8","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.1","Brain RNA - amygdala [nTPM]":"2.0","Brain RNA - basal ganglia [nTPM]":"3.7","Brain RNA - cerebellum [nTPM]":"11.6","Brain RNA - cerebral cortex [nTPM]":"5.7","Brain RNA - hippocampal formation [nTPM]":"2.6","Brain RNA - hypothalamus [nTPM]":"0.2","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"3.8","Single Cell Type RNA - Adipocytes [nTPM]":"7.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.8","Single Cell Type RNA - Astrocytes [nTPM]":"85.5","Single Cell Type RNA - B-cells [nTPM]":"42.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"15.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"8.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"7.4","Single Cell Type RNA - Bipolar cells [nTPM]":"12.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"11.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"14.3","Single Cell Type RNA - Club cells [nTPM]":"4.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.5","Single Cell Type RNA - dendritic cells [nTPM]":"25.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"1.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.5","Single Cell Type RNA - Early spermatids [nTPM]":"1.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"12.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.6","Single Cell Type RNA - Endothelial cells [nTPM]":"8.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"349.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.4","Single Cell Type RNA - Fibroblasts [nTPM]":"29.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"17.9","Single Cell Type RNA - Hepatocytes [nTPM]":"16.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"2.0","Single Cell Type RNA - Horizontal cells [nTPM]":"3.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"548.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"4.4","Single Cell Type RNA - Ionocytes [nTPM]":"10.2","Single Cell Type RNA - Kupffer cells [nTPM]":"2.4","Single Cell Type RNA - Langerhans cells [nTPM]":"8.7","Single Cell Type RNA - Late spermatids [nTPM]":"3.7","Single Cell Type RNA - Leydig cells [nTPM]":"62.7","Single Cell Type RNA - Macrophages [nTPM]":"4.6","Single Cell Type RNA - Melanocytes [nTPM]":"3.6","Single Cell Type RNA - Microglial cells [nTPM]":"88.1","Single Cell Type RNA - monocytes [nTPM]":"1.5","Single Cell Type RNA - Muller glia cells [nTPM]":"10.7","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"170.4","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"3.7","Single Cell Type RNA - Paneth cells [nTPM]":"9.1","Single Cell Type RNA - Peritubular cells [nTPM]":"39.9","Single Cell Type RNA - Plasma cells [nTPM]":"29.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"18.2","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"28.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"4.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"5.9","Single Cell Type RNA - Theca cells [nTPM]":"0.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"4.7","Single Cell Type RNA - Urothelial cells [nTPM]":"1.5"},{"Gene":"SF3B1","Gene synonym":["Hsh155","Prp10","PRPF10","SAP155","SF3b155"],"Ensembl":"ENSG00000115524","Gene description":"Splicing factor 3b subunit 1","Uniprot":["O75533"],"Chromosome":"2","Position":"197388515-197435079","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA050275"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"94000","Blood expression cluster":"Cluster 31: Non-specific - Inflammatory response","Tissue expression cluster":"Cluster 50: Non-specific - Ribosome","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 10: Non-specific - Unknown function","Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA050275":"AB_2681071"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.86e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.78e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.42e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.44e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.20e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.79e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.79e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.41e-2"},"Tissue RNA - adipose tissue [nTPM]":"183.8","Tissue RNA - adrenal gland [nTPM]":"173.9","Tissue RNA - amygdala [nTPM]":"101.7","Tissue RNA - appendix [nTPM]":"132.7","Tissue RNA - basal ganglia [nTPM]":"112.4","Tissue RNA - bone marrow [nTPM]":"304.8","Tissue RNA - breast [nTPM]":"180.7","Tissue RNA - cerebellum [nTPM]":"120.5","Tissue RNA - cerebral cortex [nTPM]":"126.1","Tissue RNA - cervix [nTPM]":"222.8","Tissue RNA - choroid plexus [nTPM]":"136.8","Tissue RNA - colon [nTPM]":"170.9","Tissue RNA - duodenum [nTPM]":"110.4","Tissue RNA - endometrium 1 [nTPM]":"195.8","Tissue RNA - epididymis [nTPM]":"200.0","Tissue RNA - esophagus [nTPM]":"136.8","Tissue RNA - fallopian tube [nTPM]":"183.8","Tissue RNA - gallbladder [nTPM]":"123.2","Tissue RNA - heart muscle [nTPM]":"135.7","Tissue RNA - hippocampal formation [nTPM]":"98.2","Tissue RNA - hypothalamus [nTPM]":"100.8","Tissue RNA - kidney [nTPM]":"135.4","Tissue RNA - liver [nTPM]":"168.5","Tissue RNA - lung [nTPM]":"162.8","Tissue RNA - lymph node [nTPM]":"203.0","Tissue RNA - medulla oblongata [nTPM]":"105.7","Tissue RNA - midbrain [nTPM]":"101.9","Tissue RNA - ovary [nTPM]":"226.5","Tissue RNA - pancreas [nTPM]":"200.7","Tissue RNA - parathyroid gland [nTPM]":"154.9","Tissue RNA - pituitary gland [nTPM]":"147.8","Tissue RNA - placenta [nTPM]":"165.3","Tissue RNA - pons [nTPM]":"111.0","Tissue RNA - prostate [nTPM]":"163.2","Tissue RNA - rectum [nTPM]":"147.3","Tissue RNA - retina [nTPM]":"138.4","Tissue RNA - salivary gland [nTPM]":"180.4","Tissue RNA - seminal vesicle [nTPM]":"133.2","Tissue RNA - skeletal muscle [nTPM]":"172.4","Tissue RNA - skin 1 [nTPM]":"156.5","Tissue RNA - small intestine [nTPM]":"231.6","Tissue RNA - smooth muscle [nTPM]":"116.5","Tissue RNA - spinal cord [nTPM]":"107.5","Tissue RNA - spleen [nTPM]":"287.8","Tissue RNA - stomach 1 [nTPM]":"169.2","Tissue RNA - testis [nTPM]":"91.4","Tissue RNA - thalamus [nTPM]":"104.9","Tissue RNA - thymus [nTPM]":"221.9","Tissue RNA - thyroid gland [nTPM]":"167.8","Tissue RNA - tongue [nTPM]":"144.8","Tissue RNA - tonsil [nTPM]":"199.3","Tissue RNA - urinary bladder [nTPM]":"154.4","Tissue RNA - vagina [nTPM]":"167.1","Tissue RNA - white matter [nTPM]":"135.8","Cell RNA - A-431 [nTPM]":"134.9","Cell RNA - A549 [nTPM]":"105.4","Cell RNA - AF22 [nTPM]":"288.6","Cell RNA - AN3-CA [nTPM]":"155.9","Cell RNA - ASC diff [nTPM]":"222.8","Cell RNA - ASC TERT1 [nTPM]":"219.2","Cell RNA - BEWO [nTPM]":"237.8","Cell RNA - BJ [nTPM]":"172.6","Cell RNA - BJ hTERT+ [nTPM]":"196.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"163.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"205.9","Cell RNA - CACO-2 [nTPM]":"233.0","Cell RNA - CAPAN-2 [nTPM]":"147.2","Cell RNA - Daudi [nTPM]":"247.5","Cell RNA - EFO-21 [nTPM]":"116.6","Cell RNA - fHDF\/TERT166 [nTPM]":"193.1","Cell RNA - GAMG [nTPM]":"165.8","Cell RNA - HaCaT [nTPM]":"133.7","Cell RNA - HAP1 [nTPM]":"273.4","Cell RNA - HBEC3-KT [nTPM]":"151.2","Cell RNA - HBF TERT88 [nTPM]":"271.8","Cell RNA - HDLM-2 [nTPM]":"196.5","Cell RNA - HEK 293 [nTPM]":"154.8","Cell RNA - HEL [nTPM]":"237.5","Cell RNA - HeLa [nTPM]":"257.4","Cell RNA - Hep G2 [nTPM]":"294.3","Cell RNA - HHSteC [nTPM]":"155.4","Cell RNA - HL-60 [nTPM]":"270.1","Cell RNA - HMC-1 [nTPM]":"198.6","Cell RNA - HSkMC [nTPM]":"232.1","Cell RNA - hTCEpi [nTPM]":"163.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"175.9","Cell RNA - hTERT-HME1 [nTPM]":"209.3","Cell RNA - hTERT-RPE1 [nTPM]":"278.6","Cell RNA - HUVEC TERT2 [nTPM]":"205.9","Cell RNA - JURKAT [nTPM]":"171.0","Cell RNA - K-562 [nTPM]":"210.2","Cell RNA - Karpas-707 [nTPM]":"174.0","Cell RNA - LHCN-M2 [nTPM]":"192.3","Cell RNA - MCF7 [nTPM]":"134.2","Cell RNA - MOLT-4 [nTPM]":"251.1","Cell RNA - NB-4 [nTPM]":"285.6","Cell RNA - NTERA-2 [nTPM]":"231.4","Cell RNA - OE19 [nTPM]":"167.5","Cell RNA - PC-3 [nTPM]":"163.8","Cell RNA - REH [nTPM]":"234.4","Cell RNA - RH-30 [nTPM]":"197.9","Cell RNA - RPMI-8226 [nTPM]":"182.9","Cell RNA - RPTEC TERT1 [nTPM]":"245.8","Cell RNA - RT4 [nTPM]":"286.4","Cell RNA - SCLC-21H [nTPM]":"154.2","Cell RNA - SH-SY5Y [nTPM]":"186.7","Cell RNA - SiHa [nTPM]":"174.7","Cell RNA - SK-BR-3 [nTPM]":"118.2","Cell RNA - SK-MEL-30 [nTPM]":"139.2","Cell RNA - SuSa [nTPM]":"345.1","Cell RNA - T-47d [nTPM]":"115.2","Cell RNA - THP-1 [nTPM]":"242.5","Cell RNA - TIME [nTPM]":"186.8","Cell RNA - U-138 MG [nTPM]":"126.9","Cell RNA - U-2 OS [nTPM]":"109.4","Cell RNA - U-2197 [nTPM]":"123.3","Cell RNA - U-251 MG [nTPM]":"145.8","Cell RNA - U-266\/70 [nTPM]":"168.7","Cell RNA - U-266\/84 [nTPM]":"238.8","Cell RNA - U-698 [nTPM]":"342.0","Cell RNA - U-87 MG [nTPM]":"123.7","Cell RNA - U-937 [nTPM]":"174.8","Cell RNA - WM-115 [nTPM]":"146.5","Blood RNA - basophil [nTPM]":"49.8","Blood RNA - classical monocyte [nTPM]":"50.4","Blood RNA - eosinophil [nTPM]":"57.5","Blood RNA - gdT-cell [nTPM]":"54.5","Blood RNA - intermediate monocyte [nTPM]":"51.7","Blood RNA - MAIT T-cell [nTPM]":"55.4","Blood RNA - memory B-cell [nTPM]":"46.1","Blood RNA - memory CD4 T-cell [nTPM]":"46.2","Blood RNA - memory CD8 T-cell [nTPM]":"50.9","Blood RNA - myeloid DC [nTPM]":"60.5","Blood RNA - naive B-cell [nTPM]":"44.1","Blood RNA - naive CD4 T-cell [nTPM]":"48.7","Blood RNA - naive CD8 T-cell [nTPM]":"49.2","Blood RNA - neutrophil [nTPM]":"60.8","Blood RNA - NK-cell [nTPM]":"56.7","Blood RNA - non-classical monocyte [nTPM]":"52.5","Blood RNA - plasmacytoid DC [nTPM]":"37.5","Blood RNA - T-reg [nTPM]":"71.3","Blood RNA - total PBMC [nTPM]":"56.2","Brain RNA - amygdala [nTPM]":"101.7","Brain RNA - basal ganglia [nTPM]":"112.4","Brain RNA - cerebellum [nTPM]":"120.5","Brain RNA - cerebral cortex [nTPM]":"126.1","Brain RNA - hippocampal formation [nTPM]":"98.2","Brain RNA - hypothalamus [nTPM]":"100.8","Brain RNA - medulla oblongata [nTPM]":"105.7","Brain RNA - midbrain [nTPM]":"101.9","Brain RNA - pons [nTPM]":"111.0","Brain RNA - spinal cord [nTPM]":"107.5","Brain RNA - thalamus [nTPM]":"104.9","Brain RNA - white matter [nTPM]":"135.8","Single Cell Type RNA - Adipocytes [nTPM]":"175.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"179.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"222.9","Single Cell Type RNA - Astrocytes [nTPM]":"92.4","Single Cell Type RNA - B-cells [nTPM]":"187.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"119.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"172.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"127.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"125.7","Single Cell Type RNA - Bipolar cells [nTPM]":"103.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"96.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"83.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"129.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"72.9","Single Cell Type RNA - Club cells [nTPM]":"194.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"92.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"73.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"116.8","Single Cell Type RNA - dendritic cells [nTPM]":"224.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"90.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"56.7","Single Cell Type RNA - Ductal cells [nTPM]":"104.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"123.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"191.0","Single Cell Type RNA - Endothelial cells [nTPM]":"143.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"110.5","Single Cell Type RNA - Erythroid cells [nTPM]":"109.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"55.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"94.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"102.3","Single Cell Type RNA - Fibroblasts [nTPM]":"151.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"132.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"179.0","Single Cell Type RNA - granulocytes [nTPM]":"246.9","Single Cell Type RNA - Granulosa cells [nTPM]":"171.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"107.1","Single Cell Type RNA - Hepatocytes [nTPM]":"74.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"100.6","Single Cell Type RNA - Horizontal cells [nTPM]":"94.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"108.1","Single Cell Type RNA - Ionocytes [nTPM]":"89.5","Single Cell Type RNA - Kupffer cells [nTPM]":"124.7","Single Cell Type RNA - Langerhans cells [nTPM]":"144.1","Single Cell Type RNA - Late spermatids [nTPM]":"20.6","Single Cell Type RNA - Leydig cells [nTPM]":"120.2","Single Cell Type RNA - Macrophages [nTPM]":"166.1","Single Cell Type RNA - Melanocytes [nTPM]":"76.5","Single Cell Type RNA - Microglial cells [nTPM]":"75.9","Single Cell Type RNA - monocytes [nTPM]":"163.9","Single Cell Type RNA - Muller glia cells [nTPM]":"111.1","Single Cell Type RNA - NK-cells [nTPM]":"116.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"87.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"121.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"112.0","Single Cell Type RNA - Paneth cells [nTPM]":"68.3","Single Cell Type RNA - Peritubular cells [nTPM]":"104.6","Single Cell Type RNA - Plasma cells [nTPM]":"195.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"103.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"84.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"70.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"221.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"98.5","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"159.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"227.9","Single Cell Type RNA - Spermatocytes [nTPM]":"104.6","Single Cell Type RNA - Spermatogonia [nTPM]":"100.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"94.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"118.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"142.7","Single Cell Type RNA - T-cells [nTPM]":"216.2","Single Cell Type RNA - Theca cells [nTPM]":"119.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"91.4","Single Cell Type RNA - Urothelial cells [nTPM]":"156.1"},{"Gene":"SHH","Gene synonym":["HHG1","HLP3","HPE3","MCOPCB5","SMMCI","TPT","TPTPS"],"Ensembl":"ENSG00000164690","Gene description":"Sonic hedgehog signaling molecule","Uniprot":["Q15465"],"Chromosome":"7","Position":"155799980-155812463","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein","Hydrolase","Protease"],"Disease involvement":["Disease variant","Holoprosencephaly","Microphthalmia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"13.6","stomach 1":"10.5","urinary bladder":"16.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal prostatic cells":"8.3","Cholangiocytes":"18.6","Collecting duct cells":"9.2","Gastric mucus-secreting cells":"9.7","Hepatocytes":"20.1","Intestinal goblet cells":"8.6","Pancreatic endocrine cells":"11.7","Urothelial cells":"8.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"EFO-21":"8.9","GAMG":"39.8","OE19":"10.2","RT4":"25.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"5500000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 85: Liver - Metabolism","Cell line expression cluster":"Cluster 4: Mesenchymal cell lines - Antiviral immune response","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.17e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.68e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.70e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.62e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.50e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.39e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.82e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.47e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.56e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.86e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.85e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.43e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.66e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"8.7","Tissue RNA - amygdala [nTPM]":"1.3","Tissue RNA - appendix [nTPM]":"0.3","Tissue RNA - basal ganglia [nTPM]":"1.2","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"1.6","Tissue RNA - cerebral cortex [nTPM]":"1.2","Tissue RNA - cervix [nTPM]":"4.4","Tissue RNA - choroid plexus [nTPM]":"0.3","Tissue RNA - colon [nTPM]":"1.3","Tissue RNA - duodenum [nTPM]":"1.4","Tissue RNA - endometrium 1 [nTPM]":"0.4","Tissue RNA - epididymis [nTPM]":"3.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"3.8","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.8","Tissue RNA - hypothalamus [nTPM]":"6.2","Tissue RNA - kidney [nTPM]":"3.3","Tissue RNA - liver [nTPM]":"13.6","Tissue RNA - lung [nTPM]":"1.7","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"3.3","Tissue RNA - midbrain [nTPM]":"1.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.2","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.1","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"4.6","Tissue RNA - prostate [nTPM]":"1.2","Tissue RNA - rectum [nTPM]":"1.0","Tissue RNA - retina [nTPM]":"0.3","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"1.4","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"1.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"10.5","Tissue RNA - testis [nTPM]":"0.1","Tissue RNA - thalamus [nTPM]":"2.6","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"16.2","Tissue RNA - vagina [nTPM]":"0.3","Tissue RNA - white matter [nTPM]":"1.6","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"1.3","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"5.2","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"8.9","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"39.8","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"3.9","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.1","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"10.2","Cell RNA - PC-3 [nTPM]":"4.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"2.0","Cell RNA - RT4 [nTPM]":"25.7","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.1","Cell RNA - TIME [nTPM]":"2.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.2","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.1","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.1","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"1.3","Brain RNA - basal ganglia [nTPM]":"1.2","Brain RNA - cerebellum [nTPM]":"1.6","Brain RNA - cerebral cortex [nTPM]":"1.2","Brain RNA - hippocampal formation [nTPM]":"0.8","Brain RNA - hypothalamus [nTPM]":"6.2","Brain RNA - medulla oblongata [nTPM]":"3.3","Brain RNA - midbrain [nTPM]":"1.6","Brain RNA - pons [nTPM]":"4.6","Brain RNA - spinal cord [nTPM]":"1.0","Brain RNA - thalamus [nTPM]":"2.6","Brain RNA - white matter [nTPM]":"1.6","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.8","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"8.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"1.2","Single Cell Type RNA - Early spermatids [nTPM]":"4.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"5.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.5","Single Cell Type RNA - Endothelial cells [nTPM]":"0.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"0.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"7.6","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.4","Single Cell Type RNA - Hepatocytes [nTPM]":"20.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.6","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.7","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.2","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.1","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"11.7","Single Cell Type RNA - Paneth cells [nTPM]":"0.5","Single Cell Type RNA - Peritubular cells [nTPM]":"0.4","Single Cell Type RNA - Plasma cells [nTPM]":"0.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"1.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"2.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"8.3"},{"Gene":"SMAD2","Gene synonym":["JV18-1","MADH2","MADR2"],"Ensembl":"ENSG00000175387","Gene description":"SMAD family member 2","Uniprot":["Q15796"],"Chromosome":"18","Position":"47808957-47931146","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB025507","HPA067203","CAB073546"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Cellular respiration","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 20: HeLa - Mitochondria","Single cell expression cluster":"Cluster 9: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Nucleoli","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB025507":null,"CAB073546":null,"HPA067203":"AB_2685803"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.49e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.43e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.82e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.44e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.59e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.41e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.46e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.91e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.20e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.13e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.20e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.28e-2"},"Tissue RNA - adipose tissue [nTPM]":"48.6","Tissue RNA - adrenal gland [nTPM]":"52.6","Tissue RNA - amygdala [nTPM]":"38.0","Tissue RNA - appendix [nTPM]":"38.6","Tissue RNA - basal ganglia [nTPM]":"42.4","Tissue RNA - bone marrow [nTPM]":"37.5","Tissue RNA - breast [nTPM]":"46.5","Tissue RNA - cerebellum [nTPM]":"46.2","Tissue RNA - cerebral cortex [nTPM]":"36.7","Tissue RNA - cervix [nTPM]":"43.2","Tissue RNA - choroid plexus [nTPM]":"35.6","Tissue RNA - colon [nTPM]":"47.5","Tissue RNA - duodenum [nTPM]":"36.7","Tissue RNA - endometrium 1 [nTPM]":"38.6","Tissue RNA - epididymis [nTPM]":"41.0","Tissue RNA - esophagus [nTPM]":"55.0","Tissue RNA - fallopian tube [nTPM]":"46.8","Tissue RNA - gallbladder [nTPM]":"39.6","Tissue RNA - heart muscle [nTPM]":"53.8","Tissue RNA - hippocampal formation [nTPM]":"32.9","Tissue RNA - hypothalamus [nTPM]":"48.6","Tissue RNA - kidney [nTPM]":"43.3","Tissue RNA - liver [nTPM]":"35.6","Tissue RNA - lung [nTPM]":"46.7","Tissue RNA - lymph node [nTPM]":"44.5","Tissue RNA - medulla oblongata [nTPM]":"50.2","Tissue RNA - midbrain [nTPM]":"43.2","Tissue RNA - ovary [nTPM]":"52.5","Tissue RNA - pancreas [nTPM]":"40.4","Tissue RNA - parathyroid gland [nTPM]":"44.6","Tissue RNA - pituitary gland [nTPM]":"20.3","Tissue RNA - placenta [nTPM]":"42.7","Tissue RNA - pons [nTPM]":"51.9","Tissue RNA - prostate [nTPM]":"36.4","Tissue RNA - rectum [nTPM]":"48.7","Tissue RNA - retina [nTPM]":"70.5","Tissue RNA - salivary gland [nTPM]":"36.7","Tissue RNA - seminal vesicle [nTPM]":"44.8","Tissue RNA - skeletal muscle [nTPM]":"57.4","Tissue RNA - skin 1 [nTPM]":"34.0","Tissue RNA - small intestine [nTPM]":"37.4","Tissue RNA - smooth muscle [nTPM]":"47.9","Tissue RNA - spinal cord [nTPM]":"47.8","Tissue RNA - spleen [nTPM]":"47.5","Tissue RNA - stomach 1 [nTPM]":"45.2","Tissue RNA - testis [nTPM]":"51.5","Tissue RNA - thalamus [nTPM]":"42.4","Tissue RNA - thymus [nTPM]":"72.4","Tissue RNA - thyroid gland [nTPM]":"75.7","Tissue RNA - tongue [nTPM]":"55.5","Tissue RNA - tonsil [nTPM]":"55.2","Tissue RNA - urinary bladder [nTPM]":"53.8","Tissue RNA - vagina [nTPM]":"31.1","Tissue RNA - white matter [nTPM]":"59.4","Cell RNA - A-431 [nTPM]":"81.1","Cell RNA - A549 [nTPM]":"113.7","Cell RNA - AF22 [nTPM]":"68.0","Cell RNA - AN3-CA [nTPM]":"66.2","Cell RNA - ASC diff [nTPM]":"106.1","Cell RNA - ASC TERT1 [nTPM]":"128.5","Cell RNA - BEWO [nTPM]":"77.4","Cell RNA - BJ [nTPM]":"86.1","Cell RNA - BJ hTERT+ [nTPM]":"102.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"87.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"101.8","Cell RNA - CACO-2 [nTPM]":"43.8","Cell RNA - CAPAN-2 [nTPM]":"75.6","Cell RNA - Daudi [nTPM]":"124.8","Cell RNA - EFO-21 [nTPM]":"60.3","Cell RNA - fHDF\/TERT166 [nTPM]":"110.0","Cell RNA - GAMG [nTPM]":"123.0","Cell RNA - HaCaT [nTPM]":"86.6","Cell RNA - HAP1 [nTPM]":"77.2","Cell RNA - HBEC3-KT [nTPM]":"96.1","Cell RNA - HBF TERT88 [nTPM]":"116.9","Cell RNA - HDLM-2 [nTPM]":"136.4","Cell RNA - HEK 293 [nTPM]":"39.3","Cell RNA - HEL [nTPM]":"106.4","Cell RNA - HeLa [nTPM]":"164.4","Cell RNA - Hep G2 [nTPM]":"71.9","Cell RNA - HHSteC [nTPM]":"123.2","Cell RNA - HL-60 [nTPM]":"149.6","Cell RNA - HMC-1 [nTPM]":"104.1","Cell RNA - HSkMC [nTPM]":"95.8","Cell RNA - hTCEpi [nTPM]":"121.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"75.5","Cell RNA - hTERT-HME1 [nTPM]":"172.9","Cell RNA - hTERT-RPE1 [nTPM]":"102.1","Cell RNA - HUVEC TERT2 [nTPM]":"98.6","Cell RNA - JURKAT [nTPM]":"99.7","Cell RNA - K-562 [nTPM]":"50.3","Cell RNA - Karpas-707 [nTPM]":"101.6","Cell RNA - LHCN-M2 [nTPM]":"109.6","Cell RNA - MCF7 [nTPM]":"52.7","Cell RNA - MOLT-4 [nTPM]":"103.4","Cell RNA - NB-4 [nTPM]":"71.6","Cell RNA - NTERA-2 [nTPM]":"33.6","Cell RNA - OE19 [nTPM]":"4.4","Cell RNA - PC-3 [nTPM]":"26.7","Cell RNA - REH [nTPM]":"74.4","Cell RNA - RH-30 [nTPM]":"98.9","Cell RNA - RPMI-8226 [nTPM]":"85.9","Cell RNA - RPTEC TERT1 [nTPM]":"197.8","Cell RNA - RT4 [nTPM]":"137.2","Cell RNA - SCLC-21H [nTPM]":"62.8","Cell RNA - SH-SY5Y [nTPM]":"73.3","Cell RNA - SiHa [nTPM]":"103.7","Cell RNA - SK-BR-3 [nTPM]":"70.1","Cell RNA - SK-MEL-30 [nTPM]":"85.7","Cell RNA - SuSa [nTPM]":"65.8","Cell RNA - T-47d [nTPM]":"53.5","Cell RNA - THP-1 [nTPM]":"97.7","Cell RNA - TIME [nTPM]":"111.4","Cell RNA - U-138 MG [nTPM]":"129.5","Cell RNA - U-2 OS [nTPM]":"74.2","Cell RNA - U-2197 [nTPM]":"35.6","Cell RNA - U-251 MG [nTPM]":"63.6","Cell RNA - U-266\/70 [nTPM]":"99.0","Cell RNA - U-266\/84 [nTPM]":"102.7","Cell RNA - U-698 [nTPM]":"108.3","Cell RNA - U-87 MG [nTPM]":"89.6","Cell RNA - U-937 [nTPM]":"99.9","Cell RNA - WM-115 [nTPM]":"97.1","Blood RNA - basophil [nTPM]":"58.8","Blood RNA - classical monocyte [nTPM]":"33.6","Blood RNA - eosinophil [nTPM]":"38.7","Blood RNA - gdT-cell [nTPM]":"23.8","Blood RNA - intermediate monocyte [nTPM]":"38.5","Blood RNA - MAIT T-cell [nTPM]":"29.8","Blood RNA - memory B-cell [nTPM]":"16.7","Blood RNA - memory CD4 T-cell [nTPM]":"32.3","Blood RNA - memory CD8 T-cell [nTPM]":"29.9","Blood RNA - myeloid DC [nTPM]":"32.8","Blood RNA - naive B-cell [nTPM]":"13.9","Blood RNA - naive CD4 T-cell [nTPM]":"35.3","Blood RNA - naive CD8 T-cell [nTPM]":"27.6","Blood RNA - neutrophil [nTPM]":"34.1","Blood RNA - NK-cell [nTPM]":"38.6","Blood RNA - non-classical monocyte [nTPM]":"33.0","Blood RNA - plasmacytoid DC [nTPM]":"23.3","Blood RNA - T-reg [nTPM]":"40.5","Blood RNA - total PBMC [nTPM]":"31.6","Brain RNA - amygdala [nTPM]":"38.0","Brain RNA - basal ganglia [nTPM]":"42.4","Brain RNA - cerebellum [nTPM]":"46.2","Brain RNA - cerebral cortex [nTPM]":"36.7","Brain RNA - hippocampal formation [nTPM]":"32.9","Brain RNA - hypothalamus [nTPM]":"48.6","Brain RNA - medulla oblongata [nTPM]":"50.2","Brain RNA - midbrain [nTPM]":"43.2","Brain RNA - pons [nTPM]":"51.9","Brain RNA - spinal cord [nTPM]":"47.8","Brain RNA - thalamus [nTPM]":"42.4","Brain RNA - white matter [nTPM]":"59.4","Single Cell Type RNA - Adipocytes [nTPM]":"55.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"44.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.1","Single Cell Type RNA - Astrocytes [nTPM]":"55.8","Single Cell Type RNA - B-cells [nTPM]":"36.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"54.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"44.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"38.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"54.1","Single Cell Type RNA - Bipolar cells [nTPM]":"48.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"44.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"49.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"41.5","Single Cell Type RNA - Club cells [nTPM]":"45.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"77.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"212.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"48.2","Single Cell Type RNA - dendritic cells [nTPM]":"53.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"42.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"39.2","Single Cell Type RNA - Ductal cells [nTPM]":"36.5","Single Cell Type RNA - Early spermatids [nTPM]":"68.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"58.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"53.0","Single Cell Type RNA - Endothelial cells [nTPM]":"53.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"51.0","Single Cell Type RNA - Erythroid cells [nTPM]":"36.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"63.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"43.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"40.3","Single Cell Type RNA - Fibroblasts [nTPM]":"40.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"68.1","Single Cell Type RNA - granulocytes [nTPM]":"21.5","Single Cell Type RNA - Granulosa cells [nTPM]":"80.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"56.4","Single Cell Type RNA - Hepatocytes [nTPM]":"29.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"43.9","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"46.1","Single Cell Type RNA - Ionocytes [nTPM]":"38.7","Single Cell Type RNA - Kupffer cells [nTPM]":"57.3","Single Cell Type RNA - Langerhans cells [nTPM]":"41.8","Single Cell Type RNA - Late spermatids [nTPM]":"131.9","Single Cell Type RNA - Leydig cells [nTPM]":"41.7","Single Cell Type RNA - Macrophages [nTPM]":"48.7","Single Cell Type RNA - Melanocytes [nTPM]":"51.6","Single Cell Type RNA - Microglial cells [nTPM]":"104.9","Single Cell Type RNA - monocytes [nTPM]":"63.9","Single Cell Type RNA - Muller glia cells [nTPM]":"44.8","Single Cell Type RNA - NK-cells [nTPM]":"72.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"96.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"130.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"44.0","Single Cell Type RNA - Paneth cells [nTPM]":"31.6","Single Cell Type RNA - Peritubular cells [nTPM]":"53.4","Single Cell Type RNA - Plasma cells [nTPM]":"34.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"66.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"39.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"41.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"88.1","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"53.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"39.6","Single Cell Type RNA - Spermatocytes [nTPM]":"37.2","Single Cell Type RNA - Spermatogonia [nTPM]":"39.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"59.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"61.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"69.5","Single Cell Type RNA - T-cells [nTPM]":"47.4","Single Cell Type RNA - Theca cells [nTPM]":"41.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"42.3","Single Cell Type RNA - Urothelial cells [nTPM]":"77.2"},{"Gene":"SMAD4","Gene synonym":["DPC4","MADH4"],"Ensembl":"ENSG00000141646","Gene description":"SMAD family member 4","Uniprot":["Q13485"],"Chromosome":"18","Position":"51028394-51085045","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Granulosa cells":"132.4"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: T-regs - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 10: BJ & FHDF - ECM organization","Single cell expression cluster":"Cluster 40: Granulosa cells - Unknown function","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Centrosome"],"Antibody RRID":{"HPA019154":"AB_1853480"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.75e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.83e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.00e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.92e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.23e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.44e-1"},"Tissue RNA - adipose tissue [nTPM]":"16.4","Tissue RNA - adrenal gland [nTPM]":"11.8","Tissue RNA - amygdala [nTPM]":"9.0","Tissue RNA - appendix [nTPM]":"10.9","Tissue RNA - basal ganglia [nTPM]":"10.3","Tissue RNA - bone marrow [nTPM]":"10.6","Tissue RNA - breast [nTPM]":"17.2","Tissue RNA - cerebellum [nTPM]":"21.7","Tissue RNA - cerebral cortex [nTPM]":"10.5","Tissue RNA - cervix [nTPM]":"18.5","Tissue RNA - choroid plexus [nTPM]":"11.2","Tissue RNA - colon [nTPM]":"14.9","Tissue RNA - duodenum [nTPM]":"11.9","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"15.7","Tissue RNA - fallopian tube [nTPM]":"16.3","Tissue RNA - gallbladder [nTPM]":"12.8","Tissue RNA - heart muscle [nTPM]":"14.1","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"16.1","Tissue RNA - liver [nTPM]":"19.1","Tissue RNA - lung [nTPM]":"13.1","Tissue RNA - lymph node [nTPM]":"12.7","Tissue RNA - medulla oblongata [nTPM]":"9.0","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"24.0","Tissue RNA - pancreas [nTPM]":"21.4","Tissue RNA - parathyroid gland [nTPM]":"19.9","Tissue RNA - pituitary gland [nTPM]":"11.3","Tissue RNA - placenta [nTPM]":"18.9","Tissue RNA - pons [nTPM]":"9.4","Tissue RNA - prostate [nTPM]":"21.8","Tissue RNA - rectum [nTPM]":"14.3","Tissue RNA - retina [nTPM]":"18.3","Tissue RNA - salivary gland [nTPM]":"14.0","Tissue RNA - seminal vesicle [nTPM]":"18.0","Tissue RNA - skeletal muscle [nTPM]":"24.9","Tissue RNA - skin 1 [nTPM]":"14.6","Tissue RNA - small intestine [nTPM]":"12.1","Tissue RNA - smooth muscle [nTPM]":"18.9","Tissue RNA - spinal cord [nTPM]":"8.0","Tissue RNA - spleen [nTPM]":"13.9","Tissue RNA - stomach 1 [nTPM]":"15.2","Tissue RNA - testis [nTPM]":"14.2","Tissue RNA - thalamus [nTPM]":"11.9","Tissue RNA - thymus [nTPM]":"17.7","Tissue RNA - thyroid gland [nTPM]":"21.4","Tissue RNA - tongue [nTPM]":"24.9","Tissue RNA - tonsil [nTPM]":"14.5","Tissue RNA - urinary bladder [nTPM]":"13.5","Tissue RNA - vagina [nTPM]":"13.1","Tissue RNA - white matter [nTPM]":"13.8","Cell RNA - A-431 [nTPM]":"16.4","Cell RNA - A549 [nTPM]":"22.5","Cell RNA - AF22 [nTPM]":"59.4","Cell RNA - AN3-CA [nTPM]":"16.6","Cell RNA - ASC diff [nTPM]":"23.9","Cell RNA - ASC TERT1 [nTPM]":"36.6","Cell RNA - BEWO [nTPM]":"31.4","Cell RNA - BJ [nTPM]":"27.7","Cell RNA - BJ hTERT+ [nTPM]":"32.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"39.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"49.6","Cell RNA - CACO-2 [nTPM]":"13.0","Cell RNA - CAPAN-2 [nTPM]":"3.8","Cell RNA - Daudi [nTPM]":"25.9","Cell RNA - EFO-21 [nTPM]":"7.8","Cell RNA - fHDF\/TERT166 [nTPM]":"25.6","Cell RNA - GAMG [nTPM]":"19.6","Cell RNA - HaCaT [nTPM]":"24.9","Cell RNA - HAP1 [nTPM]":"33.6","Cell RNA - HBEC3-KT [nTPM]":"13.2","Cell RNA - HBF TERT88 [nTPM]":"40.7","Cell RNA - HDLM-2 [nTPM]":"19.3","Cell RNA - HEK 293 [nTPM]":"14.8","Cell RNA - HEL [nTPM]":"20.6","Cell RNA - HeLa [nTPM]":"20.5","Cell RNA - Hep G2 [nTPM]":"15.9","Cell RNA - HHSteC [nTPM]":"23.7","Cell RNA - HL-60 [nTPM]":"34.8","Cell RNA - HMC-1 [nTPM]":"13.1","Cell RNA - HSkMC [nTPM]":"16.6","Cell RNA - hTCEpi [nTPM]":"21.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.1","Cell RNA - hTERT-HME1 [nTPM]":"27.8","Cell RNA - hTERT-RPE1 [nTPM]":"37.0","Cell RNA - HUVEC TERT2 [nTPM]":"28.7","Cell RNA - JURKAT [nTPM]":"14.0","Cell RNA - K-562 [nTPM]":"21.9","Cell RNA - Karpas-707 [nTPM]":"25.8","Cell RNA - LHCN-M2 [nTPM]":"23.5","Cell RNA - MCF7 [nTPM]":"9.0","Cell RNA - MOLT-4 [nTPM]":"18.8","Cell RNA - NB-4 [nTPM]":"10.0","Cell RNA - NTERA-2 [nTPM]":"31.2","Cell RNA - OE19 [nTPM]":"9.1","Cell RNA - PC-3 [nTPM]":"14.3","Cell RNA - REH [nTPM]":"23.3","Cell RNA - RH-30 [nTPM]":"30.6","Cell RNA - RPMI-8226 [nTPM]":"26.9","Cell RNA - RPTEC TERT1 [nTPM]":"18.2","Cell RNA - RT4 [nTPM]":"7.4","Cell RNA - SCLC-21H [nTPM]":"34.4","Cell RNA - SH-SY5Y [nTPM]":"20.3","Cell RNA - SiHa [nTPM]":"27.0","Cell RNA - SK-BR-3 [nTPM]":"5.0","Cell RNA - SK-MEL-30 [nTPM]":"18.8","Cell RNA - SuSa [nTPM]":"24.8","Cell RNA - T-47d [nTPM]":"13.3","Cell RNA - THP-1 [nTPM]":"19.4","Cell RNA - TIME [nTPM]":"20.0","Cell RNA - U-138 MG [nTPM]":"34.5","Cell RNA - U-2 OS [nTPM]":"13.3","Cell RNA - U-2197 [nTPM]":"8.8","Cell RNA - U-251 MG [nTPM]":"19.7","Cell RNA - U-266\/70 [nTPM]":"30.6","Cell RNA - U-266\/84 [nTPM]":"28.6","Cell RNA - U-698 [nTPM]":"26.2","Cell RNA - U-87 MG [nTPM]":"21.2","Cell RNA - U-937 [nTPM]":"12.8","Cell RNA - WM-115 [nTPM]":"22.6","Blood RNA - basophil [nTPM]":"0.3","Blood RNA - classical monocyte [nTPM]":"0.6","Blood RNA - eosinophil [nTPM]":"0.6","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"0.4","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.7","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.8","Blood RNA - myeloid DC [nTPM]":"1.2","Blood RNA - naive B-cell [nTPM]":"0.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.2","Blood RNA - naive CD8 T-cell [nTPM]":"1.5","Blood RNA - neutrophil [nTPM]":"1.0","Blood RNA - NK-cell [nTPM]":"1.0","Blood RNA - non-classical monocyte [nTPM]":"0.4","Blood RNA - plasmacytoid DC [nTPM]":"1.0","Blood RNA - T-reg [nTPM]":"1.4","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"9.0","Brain RNA - basal ganglia [nTPM]":"10.3","Brain RNA - cerebellum [nTPM]":"21.7","Brain RNA - cerebral cortex [nTPM]":"10.5","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"9.0","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"9.4","Brain RNA - spinal cord [nTPM]":"8.0","Brain RNA - thalamus [nTPM]":"11.9","Brain RNA - white matter [nTPM]":"13.8","Single Cell Type RNA - Adipocytes [nTPM]":"32.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"55.2","Single Cell Type RNA - B-cells [nTPM]":"21.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"25.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"20.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"15.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"18.8","Single Cell Type RNA - Bipolar cells [nTPM]":"17.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"27.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"38.8","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"19.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"22.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.7","Single Cell Type RNA - dendritic cells [nTPM]":"24.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"22.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"11.7","Single Cell Type RNA - Ductal cells [nTPM]":"16.9","Single Cell Type RNA - Early spermatids [nTPM]":"10.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"30.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"36.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"39.6","Single Cell Type RNA - Erythroid cells [nTPM]":"12.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"37.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"12.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.6","Single Cell Type RNA - Fibroblasts [nTPM]":"30.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"28.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"35.2","Single Cell Type RNA - granulocytes [nTPM]":"4.5","Single Cell Type RNA - Granulosa cells [nTPM]":"132.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"28.5","Single Cell Type RNA - Hepatocytes [nTPM]":"44.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.1","Single Cell Type RNA - Horizontal cells [nTPM]":"15.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"39.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"32.1","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"28.5","Single Cell Type RNA - Langerhans cells [nTPM]":"20.9","Single Cell Type RNA - Late spermatids [nTPM]":"16.2","Single Cell Type RNA - Leydig cells [nTPM]":"33.2","Single Cell Type RNA - Macrophages [nTPM]":"21.1","Single Cell Type RNA - Melanocytes [nTPM]":"28.4","Single Cell Type RNA - Microglial cells [nTPM]":"49.6","Single Cell Type RNA - monocytes [nTPM]":"16.9","Single Cell Type RNA - Muller glia cells [nTPM]":"20.4","Single Cell Type RNA - NK-cells [nTPM]":"17.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"41.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"72.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"20.1","Single Cell Type RNA - Paneth cells [nTPM]":"21.0","Single Cell Type RNA - Peritubular cells [nTPM]":"30.5","Single Cell Type RNA - Plasma cells [nTPM]":"24.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.3","Single Cell Type RNA - Proximal enterocytes [nTPM]":"26.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"22.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"20.0","Single Cell Type RNA - Sertoli cells [nTPM]":"26.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"32.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"34.2","Single Cell Type RNA - Spermatocytes [nTPM]":"17.2","Single Cell Type RNA - Spermatogonia [nTPM]":"18.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"20.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"27.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"12.6","Single Cell Type RNA - T-cells [nTPM]":"20.1","Single Cell Type RNA - Theca cells [nTPM]":"22.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"24.5","Single Cell Type RNA - Urothelial cells [nTPM]":"29.7"},{"Gene":"SMARCB1","Gene synonym":["BAF47","hSNFS","Ini1","PPP1R144","RDT","Sfh1p","SNF5","SNF5L1","Snr1"],"Ensembl":"ENSG00000099956","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1","Uniprot":["Q12824"],"Chromosome":"22","Position":"23786931-23838009","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Host-virus interaction","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Hypotrichosis","Mental retardation","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB009196","HPA018248","HPA019127"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: B-cells - Humoral immune response","Tissue expression cluster":"Cluster 72: Non-specific - Transcription","Cell line expression cluster":"Cluster 12: NES - Nervous system development","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center"],"Antibody RRID":{"CAB009196":"AB_2191983","HPA018248":"AB_1851162","HPA019127":"AB_1851165"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.60e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.63e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.01e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.52e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.10e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.03e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.10e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.43e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.24e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.58e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.57e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.04e-2"},"Tissue RNA - adipose tissue [nTPM]":"35.9","Tissue RNA - adrenal gland [nTPM]":"46.4","Tissue RNA - amygdala [nTPM]":"2.3","Tissue RNA - appendix [nTPM]":"6.9","Tissue RNA - basal ganglia [nTPM]":"2.5","Tissue RNA - bone marrow [nTPM]":"3.3","Tissue RNA - breast [nTPM]":"40.3","Tissue RNA - cerebellum [nTPM]":"4.1","Tissue RNA - cerebral cortex [nTPM]":"10.0","Tissue RNA - cervix [nTPM]":"51.5","Tissue RNA - choroid plexus [nTPM]":"2.7","Tissue RNA - colon [nTPM]":"40.9","Tissue RNA - duodenum [nTPM]":"8.1","Tissue RNA - endometrium 1 [nTPM]":"51.4","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"51.0","Tissue RNA - fallopian tube [nTPM]":"40.4","Tissue RNA - gallbladder [nTPM]":"2.2","Tissue RNA - heart muscle [nTPM]":"44.0","Tissue RNA - hippocampal formation [nTPM]":"2.3","Tissue RNA - hypothalamus [nTPM]":"2.3","Tissue RNA - kidney [nTPM]":"47.0","Tissue RNA - liver [nTPM]":"36.9","Tissue RNA - lung [nTPM]":"32.3","Tissue RNA - lymph node [nTPM]":"5.8","Tissue RNA - medulla oblongata [nTPM]":"4.3","Tissue RNA - midbrain [nTPM]":"2.7","Tissue RNA - ovary [nTPM]":"63.1","Tissue RNA - pancreas [nTPM]":"43.9","Tissue RNA - parathyroid gland [nTPM]":"1.2","Tissue RNA - pituitary gland [nTPM]":"48.0","Tissue RNA - placenta [nTPM]":"1.2","Tissue RNA - pons [nTPM]":"2.7","Tissue RNA - prostate [nTPM]":"36.6","Tissue RNA - rectum [nTPM]":"1.1","Tissue RNA - retina [nTPM]":"25.3","Tissue RNA - salivary gland [nTPM]":"44.1","Tissue RNA - seminal vesicle [nTPM]":"0.6","Tissue RNA - skeletal muscle [nTPM]":"48.1","Tissue RNA - skin 1 [nTPM]":"50.1","Tissue RNA - small intestine [nTPM]":"51.7","Tissue RNA - smooth muscle [nTPM]":"0.6","Tissue RNA - spinal cord [nTPM]":"2.2","Tissue RNA - spleen [nTPM]":"51.7","Tissue RNA - stomach 1 [nTPM]":"40.4","Tissue RNA - testis [nTPM]":"68.3","Tissue RNA - thalamus [nTPM]":"2.3","Tissue RNA - thymus [nTPM]":"3.5","Tissue RNA - thyroid gland [nTPM]":"41.3","Tissue RNA - tongue [nTPM]":"1.8","Tissue RNA - tonsil [nTPM]":"1.5","Tissue RNA - urinary bladder [nTPM]":"37.5","Tissue RNA - vagina [nTPM]":"40.9","Tissue RNA - white matter [nTPM]":"2.9","Cell RNA - A-431 [nTPM]":"2.4","Cell RNA - A549 [nTPM]":"1.6","Cell RNA - AF22 [nTPM]":"28.2","Cell RNA - AN3-CA [nTPM]":"2.6","Cell RNA - ASC diff [nTPM]":"2.7","Cell RNA - ASC TERT1 [nTPM]":"0.7","Cell RNA - BEWO [nTPM]":"5.8","Cell RNA - BJ [nTPM]":"9.2","Cell RNA - BJ hTERT+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"2.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.3","Cell RNA - CACO-2 [nTPM]":"3.4","Cell RNA - CAPAN-2 [nTPM]":"2.6","Cell RNA - Daudi [nTPM]":"24.2","Cell RNA - EFO-21 [nTPM]":"7.9","Cell RNA - fHDF\/TERT166 [nTPM]":"1.2","Cell RNA - GAMG [nTPM]":"2.9","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"6.9","Cell RNA - HBEC3-KT [nTPM]":"4.6","Cell RNA - HBF TERT88 [nTPM]":"4.5","Cell RNA - HDLM-2 [nTPM]":"4.1","Cell RNA - HEK 293 [nTPM]":"10.5","Cell RNA - HEL [nTPM]":"20.1","Cell RNA - HeLa [nTPM]":"3.2","Cell RNA - Hep G2 [nTPM]":"2.1","Cell RNA - HHSteC [nTPM]":"3.0","Cell RNA - HL-60 [nTPM]":"21.7","Cell RNA - HMC-1 [nTPM]":"5.6","Cell RNA - HSkMC [nTPM]":"1.6","Cell RNA - hTCEpi [nTPM]":"3.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.2","Cell RNA - hTERT-HME1 [nTPM]":"6.9","Cell RNA - hTERT-RPE1 [nTPM]":"1.4","Cell RNA - HUVEC TERT2 [nTPM]":"1.4","Cell RNA - JURKAT [nTPM]":"3.0","Cell RNA - K-562 [nTPM]":"5.6","Cell RNA - Karpas-707 [nTPM]":"12.9","Cell RNA - LHCN-M2 [nTPM]":"1.7","Cell RNA - MCF7 [nTPM]":"6.1","Cell RNA - MOLT-4 [nTPM]":"17.6","Cell RNA - NB-4 [nTPM]":"5.0","Cell RNA - NTERA-2 [nTPM]":"8.6","Cell RNA - OE19 [nTPM]":"7.2","Cell RNA - PC-3 [nTPM]":"5.7","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"23.1","Cell RNA - RPMI-8226 [nTPM]":"10.8","Cell RNA - RPTEC TERT1 [nTPM]":"2.3","Cell RNA - RT4 [nTPM]":"4.5","Cell RNA - SCLC-21H [nTPM]":"13.4","Cell RNA - SH-SY5Y [nTPM]":"10.1","Cell RNA - SiHa [nTPM]":"2.2","Cell RNA - SK-BR-3 [nTPM]":"0.6","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"14.8","Cell RNA - T-47d [nTPM]":"2.2","Cell RNA - THP-1 [nTPM]":"3.3","Cell RNA - TIME [nTPM]":"2.2","Cell RNA - U-138 MG [nTPM]":"2.4","Cell RNA - U-2 OS [nTPM]":"9.8","Cell RNA - U-2197 [nTPM]":"3.8","Cell RNA - U-251 MG [nTPM]":"2.7","Cell RNA - U-266\/70 [nTPM]":"13.8","Cell RNA - U-266\/84 [nTPM]":"14.3","Cell RNA - U-698 [nTPM]":"17.7","Cell RNA - U-87 MG [nTPM]":"1.8","Cell RNA - U-937 [nTPM]":"11.3","Cell RNA - WM-115 [nTPM]":"6.8","Blood RNA - basophil [nTPM]":"7.1","Blood RNA - classical monocyte [nTPM]":"12.8","Blood RNA - eosinophil [nTPM]":"6.4","Blood RNA - gdT-cell [nTPM]":"4.4","Blood RNA - intermediate monocyte [nTPM]":"13.4","Blood RNA - MAIT T-cell [nTPM]":"6.4","Blood RNA - memory B-cell [nTPM]":"24.4","Blood RNA - memory CD4 T-cell [nTPM]":"5.5","Blood RNA - memory CD8 T-cell [nTPM]":"5.7","Blood RNA - myeloid DC [nTPM]":"12.0","Blood RNA - naive B-cell [nTPM]":"9.2","Blood RNA - naive CD4 T-cell [nTPM]":"4.5","Blood RNA - naive CD8 T-cell [nTPM]":"3.0","Blood RNA - neutrophil [nTPM]":"1.1","Blood RNA - NK-cell [nTPM]":"9.8","Blood RNA - non-classical monocyte [nTPM]":"16.8","Blood RNA - plasmacytoid DC [nTPM]":"13.3","Blood RNA - T-reg [nTPM]":"10.4","Blood RNA - total PBMC [nTPM]":"8.1","Brain RNA - amygdala [nTPM]":"2.3","Brain RNA - basal ganglia [nTPM]":"2.5","Brain RNA - cerebellum [nTPM]":"4.1","Brain RNA - cerebral cortex [nTPM]":"10.0","Brain RNA - hippocampal formation [nTPM]":"2.3","Brain RNA - hypothalamus [nTPM]":"2.3","Brain RNA - medulla oblongata [nTPM]":"4.3","Brain RNA - midbrain [nTPM]":"2.7","Brain RNA - pons [nTPM]":"2.7","Brain RNA - spinal cord [nTPM]":"2.2","Brain RNA - thalamus [nTPM]":"2.3","Brain RNA - white matter [nTPM]":"2.9","Single Cell Type RNA - Adipocytes [nTPM]":"33.6","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.6","Single Cell Type RNA - Astrocytes [nTPM]":"17.0","Single Cell Type RNA - B-cells [nTPM]":"120.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"50.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"73.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"85.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"51.2","Single Cell Type RNA - Bipolar cells [nTPM]":"55.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"42.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"49.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"37.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"47.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"20.9","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"120.6","Single Cell Type RNA - dendritic cells [nTPM]":"61.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"36.6","Single Cell Type RNA - Distal tubular cells [nTPM]":"84.1","Single Cell Type RNA - Ductal cells [nTPM]":"94.6","Single Cell Type RNA - Early spermatids [nTPM]":"42.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"40.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"54.9","Single Cell Type RNA - Endothelial cells [nTPM]":"37.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"71.8","Single Cell Type RNA - Erythroid cells [nTPM]":"57.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"77.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"228.1","Single Cell Type RNA - Fibroblasts [nTPM]":"46.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"41.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"41.1","Single Cell Type RNA - granulocytes [nTPM]":"34.8","Single Cell Type RNA - Granulosa cells [nTPM]":"112.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.0","Single Cell Type RNA - Hepatocytes [nTPM]":"20.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"76.1","Single Cell Type RNA - Horizontal cells [nTPM]":"67.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"54.6","Single Cell Type RNA - Ionocytes [nTPM]":"99.7","Single Cell Type RNA - Kupffer cells [nTPM]":"23.0","Single Cell Type RNA - Langerhans cells [nTPM]":"41.7","Single Cell Type RNA - Late spermatids [nTPM]":"18.9","Single Cell Type RNA - Leydig cells [nTPM]":"35.8","Single Cell Type RNA - Macrophages [nTPM]":"36.5","Single Cell Type RNA - Melanocytes [nTPM]":"56.9","Single Cell Type RNA - Microglial cells [nTPM]":"15.9","Single Cell Type RNA - monocytes [nTPM]":"51.2","Single Cell Type RNA - Muller glia cells [nTPM]":"92.4","Single Cell Type RNA - NK-cells [nTPM]":"45.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"18.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.7","Single Cell Type RNA - Paneth cells [nTPM]":"53.1","Single Cell Type RNA - Peritubular cells [nTPM]":"32.0","Single Cell Type RNA - Plasma cells [nTPM]":"139.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"74.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"41.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"86.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"28.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"49.6","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"62.8","Single Cell Type RNA - Spermatocytes [nTPM]":"138.9","Single Cell Type RNA - Spermatogonia [nTPM]":"163.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"64.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"53.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"160.1","Single Cell Type RNA - T-cells [nTPM]":"42.0","Single Cell Type RNA - Theca cells [nTPM]":"96.8","Single Cell Type RNA - Undifferentiated cells [nTPM]":"65.4","Single Cell Type RNA - Urothelial cells [nTPM]":"65.1"},{"Gene":"SMARCE1","Gene synonym":["BAF57"],"Ensembl":"ENSG00000073584","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1","Uniprot":["Q969G3"],"Chromosome":"17","Position":"40624962-40648654","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Neurogenesis"],"Molecular function":["Chromatin regulator","DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA003916","CAB037318"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Basic cellular processes","Tissue expression cluster":"Cluster 34: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: JURKAT & MOLT-4 - Adaptive immune response","Single cell expression cluster":"Cluster 59: Non-specific - Transcription","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB037318":"AB_476780","HPA003916":"AB_1857279"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.91e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-3"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.20e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.05e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.53e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.93e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.27e-2"},"Tissue RNA - adipose tissue [nTPM]":"39.4","Tissue RNA - adrenal gland [nTPM]":"22.2","Tissue RNA - amygdala [nTPM]":"10.5","Tissue RNA - appendix [nTPM]":"37.8","Tissue RNA - basal ganglia [nTPM]":"11.9","Tissue RNA - bone marrow [nTPM]":"43.2","Tissue RNA - breast [nTPM]":"35.6","Tissue RNA - cerebellum [nTPM]":"10.6","Tissue RNA - cerebral cortex [nTPM]":"13.3","Tissue RNA - cervix [nTPM]":"45.9","Tissue RNA - choroid plexus [nTPM]":"14.3","Tissue RNA - colon [nTPM]":"40.2","Tissue RNA - duodenum [nTPM]":"38.9","Tissue RNA - endometrium 1 [nTPM]":"56.2","Tissue RNA - epididymis [nTPM]":"28.3","Tissue RNA - esophagus [nTPM]":"43.6","Tissue RNA - fallopian tube [nTPM]":"39.0","Tissue RNA - gallbladder [nTPM]":"41.4","Tissue RNA - heart muscle [nTPM]":"40.1","Tissue RNA - hippocampal formation [nTPM]":"9.2","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"31.2","Tissue RNA - liver [nTPM]":"31.5","Tissue RNA - lung [nTPM]":"36.1","Tissue RNA - lymph node [nTPM]":"49.6","Tissue RNA - medulla oblongata [nTPM]":"13.7","Tissue RNA - midbrain [nTPM]":"10.7","Tissue RNA - ovary [nTPM]":"58.6","Tissue RNA - pancreas [nTPM]":"35.4","Tissue RNA - parathyroid gland [nTPM]":"38.3","Tissue RNA - pituitary gland [nTPM]":"13.3","Tissue RNA - placenta [nTPM]":"48.4","Tissue RNA - pons [nTPM]":"13.2","Tissue RNA - prostate [nTPM]":"34.2","Tissue RNA - rectum [nTPM]":"38.5","Tissue RNA - retina [nTPM]":"17.5","Tissue RNA - salivary gland [nTPM]":"33.6","Tissue RNA - seminal vesicle [nTPM]":"42.1","Tissue RNA - skeletal muscle [nTPM]":"42.5","Tissue RNA - skin 1 [nTPM]":"27.7","Tissue RNA - small intestine [nTPM]":"39.3","Tissue RNA - smooth muscle [nTPM]":"57.4","Tissue RNA - spinal cord [nTPM]":"11.7","Tissue RNA - spleen [nTPM]":"40.5","Tissue RNA - stomach 1 [nTPM]":"30.9","Tissue RNA - testis [nTPM]":"31.5","Tissue RNA - thalamus [nTPM]":"11.2","Tissue RNA - thymus [nTPM]":"76.1","Tissue RNA - thyroid gland [nTPM]":"40.8","Tissue RNA - tongue [nTPM]":"44.7","Tissue RNA - tonsil [nTPM]":"54.2","Tissue RNA - urinary bladder [nTPM]":"46.8","Tissue RNA - vagina [nTPM]":"26.2","Tissue RNA - white matter [nTPM]":"16.5","Cell RNA - A-431 [nTPM]":"86.5","Cell RNA - A549 [nTPM]":"139.6","Cell RNA - AF22 [nTPM]":"169.1","Cell RNA - AN3-CA [nTPM]":"126.5","Cell RNA - ASC diff [nTPM]":"87.7","Cell RNA - ASC TERT1 [nTPM]":"125.5","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"105.9","Cell RNA - BJ hTERT+ [nTPM]":"145.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"122.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"91.0","Cell RNA - CACO-2 [nTPM]":"92.7","Cell RNA - CAPAN-2 [nTPM]":"72.7","Cell RNA - Daudi [nTPM]":"135.9","Cell RNA - EFO-21 [nTPM]":"149.6","Cell RNA - fHDF\/TERT166 [nTPM]":"145.3","Cell RNA - GAMG [nTPM]":"81.0","Cell RNA - HaCaT [nTPM]":"114.5","Cell RNA - HAP1 [nTPM]":"106.1","Cell RNA - HBEC3-KT [nTPM]":"112.3","Cell RNA - HBF TERT88 [nTPM]":"145.1","Cell RNA - HDLM-2 [nTPM]":"128.3","Cell RNA - HEK 293 [nTPM]":"138.0","Cell RNA - HEL [nTPM]":"97.2","Cell RNA - HeLa [nTPM]":"73.4","Cell RNA - Hep G2 [nTPM]":"165.2","Cell RNA - HHSteC [nTPM]":"87.8","Cell RNA - HL-60 [nTPM]":"179.8","Cell RNA - HMC-1 [nTPM]":"94.5","Cell RNA - HSkMC [nTPM]":"109.3","Cell RNA - hTCEpi [nTPM]":"87.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"97.7","Cell RNA - hTERT-HME1 [nTPM]":"140.6","Cell RNA - hTERT-RPE1 [nTPM]":"122.1","Cell RNA - HUVEC TERT2 [nTPM]":"133.4","Cell RNA - JURKAT [nTPM]":"106.5","Cell RNA - K-562 [nTPM]":"144.2","Cell RNA - Karpas-707 [nTPM]":"52.2","Cell RNA - LHCN-M2 [nTPM]":"118.2","Cell RNA - MCF7 [nTPM]":"96.5","Cell RNA - MOLT-4 [nTPM]":"331.6","Cell RNA - NB-4 [nTPM]":"37.1","Cell RNA - NTERA-2 [nTPM]":"95.4","Cell RNA - OE19 [nTPM]":"70.8","Cell RNA - PC-3 [nTPM]":"68.6","Cell RNA - REH [nTPM]":"183.3","Cell RNA - RH-30 [nTPM]":"190.2","Cell RNA - RPMI-8226 [nTPM]":"103.7","Cell RNA - RPTEC TERT1 [nTPM]":"147.5","Cell RNA - RT4 [nTPM]":"144.9","Cell RNA - SCLC-21H [nTPM]":"134.6","Cell RNA - SH-SY5Y [nTPM]":"130.0","Cell RNA - SiHa [nTPM]":"94.5","Cell RNA - SK-BR-3 [nTPM]":"269.4","Cell RNA - SK-MEL-30 [nTPM]":"86.6","Cell RNA - SuSa [nTPM]":"181.5","Cell RNA - T-47d [nTPM]":"161.5","Cell RNA - THP-1 [nTPM]":"111.4","Cell RNA - TIME [nTPM]":"109.7","Cell RNA - U-138 MG [nTPM]":"98.1","Cell RNA - U-2 OS [nTPM]":"107.6","Cell RNA - U-2197 [nTPM]":"89.7","Cell RNA - U-251 MG [nTPM]":"132.6","Cell RNA - U-266\/70 [nTPM]":"97.7","Cell RNA - U-266\/84 [nTPM]":"122.8","Cell RNA - U-698 [nTPM]":"204.5","Cell RNA - U-87 MG [nTPM]":"100.0","Cell RNA - U-937 [nTPM]":"80.9","Cell RNA - WM-115 [nTPM]":"154.9","Blood RNA - basophil [nTPM]":"106.3","Blood RNA - classical monocyte [nTPM]":"64.4","Blood RNA - eosinophil [nTPM]":"88.2","Blood RNA - gdT-cell [nTPM]":"91.7","Blood RNA - intermediate monocyte [nTPM]":"67.8","Blood RNA - MAIT T-cell [nTPM]":"95.0","Blood RNA - memory B-cell [nTPM]":"99.8","Blood RNA - memory CD4 T-cell [nTPM]":"82.4","Blood RNA - memory CD8 T-cell [nTPM]":"96.1","Blood RNA - myeloid DC [nTPM]":"77.9","Blood RNA - naive B-cell [nTPM]":"112.3","Blood RNA - naive CD4 T-cell [nTPM]":"68.3","Blood RNA - naive CD8 T-cell [nTPM]":"79.3","Blood RNA - neutrophil [nTPM]":"26.5","Blood RNA - NK-cell [nTPM]":"124.7","Blood RNA - non-classical monocyte [nTPM]":"82.2","Blood RNA - plasmacytoid DC [nTPM]":"80.3","Blood RNA - T-reg [nTPM]":"114.7","Blood RNA - total PBMC [nTPM]":"112.2","Brain RNA - amygdala [nTPM]":"10.5","Brain RNA - basal ganglia [nTPM]":"11.9","Brain RNA - cerebellum [nTPM]":"10.6","Brain RNA - cerebral cortex [nTPM]":"13.3","Brain RNA - hippocampal formation [nTPM]":"9.2","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"13.7","Brain RNA - midbrain [nTPM]":"10.7","Brain RNA - pons [nTPM]":"13.2","Brain RNA - spinal cord [nTPM]":"11.7","Brain RNA - thalamus [nTPM]":"11.2","Brain RNA - white matter [nTPM]":"16.5","Single Cell Type RNA - Adipocytes [nTPM]":"41.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"45.1","Single Cell Type RNA - Astrocytes [nTPM]":"13.1","Single Cell Type RNA - B-cells [nTPM]":"67.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"38.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"43.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"69.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"65.4","Single Cell Type RNA - Bipolar cells [nTPM]":"75.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"19.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"20.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"53.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"38.6","Single Cell Type RNA - Club cells [nTPM]":"61.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"101.8","Single Cell Type RNA - dendritic cells [nTPM]":"68.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"38.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"41.5","Single Cell Type RNA - Early spermatids [nTPM]":"27.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"34.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"47.0","Single Cell Type RNA - Endothelial cells [nTPM]":"60.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"96.5","Single Cell Type RNA - Erythroid cells [nTPM]":"84.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"17.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"75.7","Single Cell Type RNA - Fibroblasts [nTPM]":"72.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"32.1","Single Cell Type RNA - granulocytes [nTPM]":"74.0","Single Cell Type RNA - Granulosa cells [nTPM]":"41.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"62.8","Single Cell Type RNA - Hepatocytes [nTPM]":"44.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"51.6","Single Cell Type RNA - Horizontal cells [nTPM]":"82.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"18.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"53.5","Single Cell Type RNA - Ionocytes [nTPM]":"65.1","Single Cell Type RNA - Kupffer cells [nTPM]":"42.9","Single Cell Type RNA - Langerhans cells [nTPM]":"39.6","Single Cell Type RNA - Late spermatids [nTPM]":"11.8","Single Cell Type RNA - Leydig cells [nTPM]":"90.4","Single Cell Type RNA - Macrophages [nTPM]":"30.9","Single Cell Type RNA - Melanocytes [nTPM]":"24.9","Single Cell Type RNA - Microglial cells [nTPM]":"19.7","Single Cell Type RNA - monocytes [nTPM]":"63.2","Single Cell Type RNA - Muller glia cells [nTPM]":"63.3","Single Cell Type RNA - NK-cells [nTPM]":"105.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"26.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"32.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"35.7","Single Cell Type RNA - Paneth cells [nTPM]":"46.7","Single Cell Type RNA - Peritubular cells [nTPM]":"82.4","Single Cell Type RNA - Plasma cells [nTPM]":"44.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"36.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"30.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"59.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"37.1","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"62.7","Single Cell Type RNA - Smooth muscle cells [nTPM]":"57.0","Single Cell Type RNA - Spermatocytes [nTPM]":"49.7","Single Cell Type RNA - Spermatogonia [nTPM]":"50.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"63.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"40.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"114.8","Single Cell Type RNA - T-cells [nTPM]":"53.8","Single Cell Type RNA - Theca cells [nTPM]":"35.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"62.5","Single Cell Type RNA - Urothelial cells [nTPM]":"34.3"},{"Gene":"SMO","Gene synonym":["FZD11","SMOH"],"Ensembl":"ENSG00000128602","Gene description":"Smoothened, frizzled class receptor","Uniprot":["Q99835"],"Chromosome":"7","Position":"129188633-129213545","Protein class":["Cancer-related genes","Disease related genes","FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":["Developmental protein","G-protein coupled receptor","Receptor","Transducer"],"Disease involvement":["Cancer-related genes","Disease variant","FDA approved drug targets"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Astrocytes":"27.4","Granulosa cells":"13.0","Leydig cells":"20.8","Muller glia cells":"16.6","Peritubular cells":"21.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"AF22":"45.3","AN3-CA":"84.9","NTERA-2":"64.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB011446"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 15: Liver - Metabolism","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB011446":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.48e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.09e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.16e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.02e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.89e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.38e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.17e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.74e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.61e-2"},"Tissue RNA - adipose tissue [nTPM]":"5.2","Tissue RNA - adrenal gland [nTPM]":"6.0","Tissue RNA - amygdala [nTPM]":"9.4","Tissue RNA - appendix [nTPM]":"2.6","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"0.4","Tissue RNA - breast [nTPM]":"5.5","Tissue RNA - cerebellum [nTPM]":"9.9","Tissue RNA - cerebral cortex [nTPM]":"9.6","Tissue RNA - cervix [nTPM]":"27.4","Tissue RNA - choroid plexus [nTPM]":"18.4","Tissue RNA - colon [nTPM]":"9.6","Tissue RNA - duodenum [nTPM]":"2.5","Tissue RNA - endometrium 1 [nTPM]":"19.2","Tissue RNA - epididymis [nTPM]":"18.6","Tissue RNA - esophagus [nTPM]":"12.0","Tissue RNA - fallopian tube [nTPM]":"14.5","Tissue RNA - gallbladder [nTPM]":"8.4","Tissue RNA - heart muscle [nTPM]":"8.0","Tissue RNA - hippocampal formation [nTPM]":"8.9","Tissue RNA - hypothalamus [nTPM]":"10.0","Tissue RNA - kidney [nTPM]":"19.0","Tissue RNA - liver [nTPM]":"23.9","Tissue RNA - lung [nTPM]":"3.6","Tissue RNA - lymph node [nTPM]":"2.2","Tissue RNA - medulla oblongata [nTPM]":"12.4","Tissue RNA - midbrain [nTPM]":"12.4","Tissue RNA - ovary [nTPM]":"28.3","Tissue RNA - pancreas [nTPM]":"6.3","Tissue RNA - parathyroid gland [nTPM]":"16.1","Tissue RNA - pituitary gland [nTPM]":"19.2","Tissue RNA - placenta [nTPM]":"2.6","Tissue RNA - pons [nTPM]":"9.9","Tissue RNA - prostate [nTPM]":"20.0","Tissue RNA - rectum [nTPM]":"2.1","Tissue RNA - retina [nTPM]":"2.0","Tissue RNA - salivary gland [nTPM]":"11.5","Tissue RNA - seminal vesicle [nTPM]":"12.3","Tissue RNA - skeletal muscle [nTPM]":"3.7","Tissue RNA - skin 1 [nTPM]":"17.1","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"8.1","Tissue RNA - spinal cord [nTPM]":"11.8","Tissue RNA - spleen [nTPM]":"2.8","Tissue RNA - stomach 1 [nTPM]":"6.3","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"11.4","Tissue RNA - thymus [nTPM]":"4.4","Tissue RNA - thyroid gland [nTPM]":"9.1","Tissue RNA - tongue [nTPM]":"3.7","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"9.0","Tissue RNA - vagina [nTPM]":"16.7","Tissue RNA - white matter [nTPM]":"9.7","Cell RNA - A-431 [nTPM]":"1.6","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"45.3","Cell RNA - AN3-CA [nTPM]":"84.9","Cell RNA - ASC diff [nTPM]":"1.1","Cell RNA - ASC TERT1 [nTPM]":"0.2","Cell RNA - BEWO [nTPM]":"14.3","Cell RNA - BJ [nTPM]":"5.2","Cell RNA - BJ hTERT+ [nTPM]":"6.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.8","Cell RNA - CACO-2 [nTPM]":"13.8","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"13.9","Cell RNA - fHDF\/TERT166 [nTPM]":"10.4","Cell RNA - GAMG [nTPM]":"22.8","Cell RNA - HaCaT [nTPM]":"28.3","Cell RNA - HAP1 [nTPM]":"27.4","Cell RNA - HBEC3-KT [nTPM]":"1.5","Cell RNA - HBF TERT88 [nTPM]":"3.9","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"23.0","Cell RNA - HEL [nTPM]":"9.4","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"22.5","Cell RNA - HHSteC [nTPM]":"5.5","Cell RNA - HL-60 [nTPM]":"0.4","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"16.2","Cell RNA - hTCEpi [nTPM]":"11.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.3","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"19.9","Cell RNA - HUVEC TERT2 [nTPM]":"5.8","Cell RNA - JURKAT [nTPM]":"24.9","Cell RNA - K-562 [nTPM]":"1.5","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"3.1","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"24.4","Cell RNA - NB-4 [nTPM]":"0.1","Cell RNA - NTERA-2 [nTPM]":"64.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"5.3","Cell RNA - REH [nTPM]":"35.1","Cell RNA - RH-30 [nTPM]":"19.7","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"5.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"1.3","Cell RNA - SH-SY5Y [nTPM]":"30.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"12.3","Cell RNA - SuSa [nTPM]":"16.8","Cell RNA - T-47d [nTPM]":"11.1","Cell RNA - THP-1 [nTPM]":"5.8","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.7","Cell RNA - U-2 OS [nTPM]":"14.1","Cell RNA - U-2197 [nTPM]":"17.6","Cell RNA - U-251 MG [nTPM]":"10.1","Cell RNA - U-266\/70 [nTPM]":"0.6","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"16.7","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"9.4","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"9.9","Brain RNA - cerebral cortex [nTPM]":"9.6","Brain RNA - hippocampal formation [nTPM]":"8.9","Brain RNA - hypothalamus [nTPM]":"10.0","Brain RNA - medulla oblongata [nTPM]":"12.4","Brain RNA - midbrain [nTPM]":"12.4","Brain RNA - pons [nTPM]":"9.9","Brain RNA - spinal cord [nTPM]":"11.8","Brain RNA - thalamus [nTPM]":"11.4","Brain RNA - white matter [nTPM]":"9.7","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"27.4","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"1.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"3.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"2.8","Single Cell Type RNA - Bipolar cells [nTPM]":"0.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.3","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"2.8","Single Cell Type RNA - Club cells [nTPM]":"3.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"11.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - dendritic cells [nTPM]":"0.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"3.4","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"8.6","Single Cell Type RNA - Endothelial cells [nTPM]":"0.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"1.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"1.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"7.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.3","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"13.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"8.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"4.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.1","Single Cell Type RNA - Ionocytes [nTPM]":"2.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.8","Single Cell Type RNA - Late spermatids [nTPM]":"1.3","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"1.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"3.7","Single Cell Type RNA - monocytes [nTPM]":"0.6","Single Cell Type RNA - Muller glia cells [nTPM]":"16.6","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"4.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"1.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"21.8","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.4","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"3.9","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"2.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"3.3","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"2.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.5","Single Cell Type RNA - T-cells [nTPM]":"0.1","Single Cell Type RNA - Theca cells [nTPM]":"6.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.6","Single Cell Type RNA - Urothelial cells [nTPM]":"0.7"},{"Gene":"SPI1","Gene synonym":["OF","PU.1","SFPI1","SPI-1","SPI-A"],"Ensembl":"ENSG00000066336","Gene description":"Spi-1 proto-oncogene","Uniprot":["P17947"],"Chromosome":"11","Position":"47354860-47378547","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","RNA-binding"],"Disease involvement":["Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"6","RNA tissue specific nTPM":{"bone marrow":"335.1","lung":"101.0","lymphoid tissue":"172.7"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Hofbauer cells":"432.9","Kupffer cells":"411.9","Langerhans cells":"537.6","Macrophages":"453.3","monocytes":"357.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"eosinophil":"179.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"179.7"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"90.1","HL-60":"159.7","HMC-1":"282.2","NB-4":"267.8","THP-1":"206.7","U-698":"85.3","U-937":"117.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB004079","HPA044653"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 3: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 4: Macrophages - Innate immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004079":"AB_10692379","HPA044653":"AB_2679036"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.45e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.66e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.28e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.36e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.07e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.95e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.92e-2"},"Tissue RNA - adipose tissue [nTPM]":"36.5","Tissue RNA - adrenal gland [nTPM]":"19.7","Tissue RNA - amygdala [nTPM]":"12.0","Tissue RNA - appendix [nTPM]":"107.3","Tissue RNA - basal ganglia [nTPM]":"13.1","Tissue RNA - bone marrow [nTPM]":"335.1","Tissue RNA - breast [nTPM]":"17.7","Tissue RNA - cerebellum [nTPM]":"14.3","Tissue RNA - cerebral cortex [nTPM]":"19.4","Tissue RNA - cervix [nTPM]":"7.9","Tissue RNA - choroid plexus [nTPM]":"15.8","Tissue RNA - colon [nTPM]":"15.6","Tissue RNA - duodenum [nTPM]":"21.5","Tissue RNA - endometrium 1 [nTPM]":"7.3","Tissue RNA - epididymis [nTPM]":"2.1","Tissue RNA - esophagus [nTPM]":"9.1","Tissue RNA - fallopian tube [nTPM]":"19.1","Tissue RNA - gallbladder [nTPM]":"21.3","Tissue RNA - heart muscle [nTPM]":"13.5","Tissue RNA - hippocampal formation [nTPM]":"11.7","Tissue RNA - hypothalamus [nTPM]":"16.4","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"15.6","Tissue RNA - lung [nTPM]":"101.0","Tissue RNA - lymph node [nTPM]":"65.0","Tissue RNA - medulla oblongata [nTPM]":"31.2","Tissue RNA - midbrain [nTPM]":"20.9","Tissue RNA - ovary [nTPM]":"5.2","Tissue RNA - pancreas [nTPM]":"7.8","Tissue RNA - parathyroid gland [nTPM]":"3.1","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"28.0","Tissue RNA - pons [nTPM]":"24.7","Tissue RNA - prostate [nTPM]":"10.3","Tissue RNA - rectum [nTPM]":"10.2","Tissue RNA - retina [nTPM]":"1.0","Tissue RNA - salivary gland [nTPM]":"14.6","Tissue RNA - seminal vesicle [nTPM]":"6.1","Tissue RNA - skeletal muscle [nTPM]":"5.0","Tissue RNA - skin 1 [nTPM]":"13.8","Tissue RNA - small intestine [nTPM]":"29.3","Tissue RNA - smooth muscle [nTPM]":"21.9","Tissue RNA - spinal cord [nTPM]":"19.8","Tissue RNA - spleen [nTPM]":"172.7","Tissue RNA - stomach 1 [nTPM]":"17.0","Tissue RNA - testis [nTPM]":"3.7","Tissue RNA - thalamus [nTPM]":"26.2","Tissue RNA - thymus [nTPM]":"15.7","Tissue RNA - thyroid gland [nTPM]":"8.8","Tissue RNA - tongue [nTPM]":"8.3","Tissue RNA - tonsil [nTPM]":"32.0","Tissue RNA - urinary bladder [nTPM]":"29.9","Tissue RNA - vagina [nTPM]":"7.6","Tissue RNA - white matter [nTPM]":"30.3","Cell RNA - A-431 [nTPM]":"0.2","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.1","Cell RNA - BEWO [nTPM]":"0.5","Cell RNA - BJ [nTPM]":"0.1","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.2","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"72.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.3","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"90.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"159.7","Cell RNA - HMC-1 [nTPM]":"282.2","Cell RNA - HSkMC [nTPM]":"0.3","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"11.7","Cell RNA - Karpas-707 [nTPM]":"0.7","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"267.8","Cell RNA - NTERA-2 [nTPM]":"0.2","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"48.7","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"47.5","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.6","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"206.7","Cell RNA - TIME [nTPM]":"0.3","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.5","Cell RNA - U-2197 [nTPM]":"0.5","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"85.3","Cell RNA - U-87 MG [nTPM]":"0.3","Cell RNA - U-937 [nTPM]":"117.5","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"14.1","Blood RNA - classical monocyte [nTPM]":"19.2","Blood RNA - eosinophil [nTPM]":"179.7","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"27.4","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"3.9","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"16.4","Blood RNA - naive B-cell [nTPM]":"2.4","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"83.8","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"34.7","Blood RNA - plasmacytoid DC [nTPM]":"0.9","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"7.3","Brain RNA - amygdala [nTPM]":"12.0","Brain RNA - basal ganglia [nTPM]":"13.1","Brain RNA - cerebellum [nTPM]":"14.3","Brain RNA - cerebral cortex [nTPM]":"19.4","Brain RNA - hippocampal formation [nTPM]":"11.7","Brain RNA - hypothalamus [nTPM]":"16.4","Brain RNA - medulla oblongata [nTPM]":"31.2","Brain RNA - midbrain [nTPM]":"20.9","Brain RNA - pons [nTPM]":"24.7","Brain RNA - spinal cord [nTPM]":"19.8","Brain RNA - thalamus [nTPM]":"26.2","Brain RNA - white matter [nTPM]":"30.3","Single Cell Type RNA - Adipocytes [nTPM]":"2.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"3.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"1.1","Single Cell Type RNA - Astrocytes [nTPM]":"10.4","Single Cell Type RNA - B-cells [nTPM]":"72.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"1.2","Single Cell Type RNA - Bipolar cells [nTPM]":"1.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"2.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"5.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"0.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"5.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"2.3","Single Cell Type RNA - dendritic cells [nTPM]":"6.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"19.6","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"7.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.3","Single Cell Type RNA - Endothelial cells [nTPM]":"5.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"4.2","Single Cell Type RNA - Erythroid cells [nTPM]":"39.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.4","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.1","Single Cell Type RNA - Fibroblasts [nTPM]":"2.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.3","Single Cell Type RNA - granulocytes [nTPM]":"33.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"7.9","Single Cell Type RNA - Hepatocytes [nTPM]":"3.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"432.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.3","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"411.9","Single Cell Type RNA - Langerhans cells [nTPM]":"537.6","Single Cell Type RNA - Late spermatids [nTPM]":"27.5","Single Cell Type RNA - Leydig cells [nTPM]":"1.8","Single Cell Type RNA - Macrophages [nTPM]":"453.3","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"36.5","Single Cell Type RNA - monocytes [nTPM]":"357.5","Single Cell Type RNA - Muller glia cells [nTPM]":"7.0","Single Cell Type RNA - NK-cells [nTPM]":"8.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"21.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.7","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"1.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.4","Single Cell Type RNA - Spermatocytes [nTPM]":"5.1","Single Cell Type RNA - Spermatogonia [nTPM]":"9.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"9.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"4.2","Single Cell Type RNA - T-cells [nTPM]":"4.8","Single Cell Type RNA - Theca cells [nTPM]":"1.1","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.4","Single Cell Type RNA - Urothelial cells [nTPM]":"0.5"},{"Gene":"SRSF2","Gene synonym":["PR264","SC-35","SC35","SFRS2","SFRS2A"],"Ensembl":"ENSG00000161547","Gene description":"Serine and arginine rich splicing factor 2","Uniprot":["Q01130"],"Chromosome":"17","Position":"76734115-76737333","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA049905"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"180000","Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 18: Non-specific - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA049905":"AB_2680945"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.50e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.16e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.73e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"8.73e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.75e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.53e-8"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.79e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.03e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.05e-7"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.85e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.95e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.87e-4"},"Tissue RNA - adipose tissue [nTPM]":"106.0","Tissue RNA - adrenal gland [nTPM]":"106.8","Tissue RNA - amygdala [nTPM]":"27.8","Tissue RNA - appendix [nTPM]":"95.5","Tissue RNA - basal ganglia [nTPM]":"29.6","Tissue RNA - bone marrow [nTPM]":"184.7","Tissue RNA - breast [nTPM]":"92.1","Tissue RNA - cerebellum [nTPM]":"29.9","Tissue RNA - cerebral cortex [nTPM]":"34.0","Tissue RNA - cervix [nTPM]":"83.6","Tissue RNA - choroid plexus [nTPM]":"37.7","Tissue RNA - colon [nTPM]":"100.3","Tissue RNA - duodenum [nTPM]":"86.2","Tissue RNA - endometrium 1 [nTPM]":"88.9","Tissue RNA - epididymis [nTPM]":"64.0","Tissue RNA - esophagus [nTPM]":"129.5","Tissue RNA - fallopian tube [nTPM]":"89.5","Tissue RNA - gallbladder [nTPM]":"42.1","Tissue RNA - heart muscle [nTPM]":"78.5","Tissue RNA - hippocampal formation [nTPM]":"29.2","Tissue RNA - hypothalamus [nTPM]":"32.9","Tissue RNA - kidney [nTPM]":"83.0","Tissue RNA - liver [nTPM]":"115.2","Tissue RNA - lung [nTPM]":"95.4","Tissue RNA - lymph node [nTPM]":"111.6","Tissue RNA - medulla oblongata [nTPM]":"30.8","Tissue RNA - midbrain [nTPM]":"28.5","Tissue RNA - ovary [nTPM]":"85.6","Tissue RNA - pancreas [nTPM]":"88.3","Tissue RNA - parathyroid gland [nTPM]":"48.4","Tissue RNA - pituitary gland [nTPM]":"81.9","Tissue RNA - placenta [nTPM]":"66.0","Tissue RNA - pons [nTPM]":"30.3","Tissue RNA - prostate [nTPM]":"78.0","Tissue RNA - rectum [nTPM]":"71.6","Tissue RNA - retina [nTPM]":"53.4","Tissue RNA - salivary gland [nTPM]":"90.6","Tissue RNA - seminal vesicle [nTPM]":"52.3","Tissue RNA - skeletal muscle [nTPM]":"91.7","Tissue RNA - skin 1 [nTPM]":"96.5","Tissue RNA - small intestine [nTPM]":"113.2","Tissue RNA - smooth muscle [nTPM]":"49.0","Tissue RNA - spinal cord [nTPM]":"31.3","Tissue RNA - spleen [nTPM]":"121.6","Tissue RNA - stomach 1 [nTPM]":"94.4","Tissue RNA - testis [nTPM]":"49.5","Tissue RNA - thalamus [nTPM]":"30.0","Tissue RNA - thymus [nTPM]":"94.2","Tissue RNA - thyroid gland [nTPM]":"102.1","Tissue RNA - tongue [nTPM]":"36.0","Tissue RNA - tonsil [nTPM]":"100.2","Tissue RNA - urinary bladder [nTPM]":"80.0","Tissue RNA - vagina [nTPM]":"94.3","Tissue RNA - white matter [nTPM]":"36.0","Cell RNA - A-431 [nTPM]":"318.7","Cell RNA - A549 [nTPM]":"239.8","Cell RNA - AF22 [nTPM]":"289.5","Cell RNA - AN3-CA [nTPM]":"207.5","Cell RNA - ASC diff [nTPM]":"70.9","Cell RNA - ASC TERT1 [nTPM]":"58.5","Cell RNA - BEWO [nTPM]":"300.5","Cell RNA - BJ [nTPM]":"197.3","Cell RNA - BJ hTERT+ [nTPM]":"146.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"225.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"207.0","Cell RNA - CACO-2 [nTPM]":"257.2","Cell RNA - CAPAN-2 [nTPM]":"216.8","Cell RNA - Daudi [nTPM]":"478.0","Cell RNA - EFO-21 [nTPM]":"143.3","Cell RNA - fHDF\/TERT166 [nTPM]":"188.7","Cell RNA - GAMG [nTPM]":"164.3","Cell RNA - HaCaT [nTPM]":"279.9","Cell RNA - HAP1 [nTPM]":"293.3","Cell RNA - HBEC3-KT [nTPM]":"229.0","Cell RNA - HBF TERT88 [nTPM]":"230.2","Cell RNA - HDLM-2 [nTPM]":"202.3","Cell RNA - HEK 293 [nTPM]":"489.3","Cell RNA - HEL [nTPM]":"357.9","Cell RNA - HeLa [nTPM]":"246.6","Cell RNA - Hep G2 [nTPM]":"311.9","Cell RNA - HHSteC [nTPM]":"79.3","Cell RNA - HL-60 [nTPM]":"404.4","Cell RNA - HMC-1 [nTPM]":"210.6","Cell RNA - HSkMC [nTPM]":"65.2","Cell RNA - hTCEpi [nTPM]":"51.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"186.2","Cell RNA - hTERT-HME1 [nTPM]":"54.0","Cell RNA - hTERT-RPE1 [nTPM]":"91.1","Cell RNA - HUVEC TERT2 [nTPM]":"179.9","Cell RNA - JURKAT [nTPM]":"212.0","Cell RNA - K-562 [nTPM]":"373.4","Cell RNA - Karpas-707 [nTPM]":"209.6","Cell RNA - LHCN-M2 [nTPM]":"183.7","Cell RNA - MCF7 [nTPM]":"251.0","Cell RNA - MOLT-4 [nTPM]":"460.0","Cell RNA - NB-4 [nTPM]":"440.9","Cell RNA - NTERA-2 [nTPM]":"339.5","Cell RNA - OE19 [nTPM]":"186.4","Cell RNA - PC-3 [nTPM]":"340.2","Cell RNA - REH [nTPM]":"455.0","Cell RNA - RH-30 [nTPM]":"310.6","Cell RNA - RPMI-8226 [nTPM]":"360.5","Cell RNA - RPTEC TERT1 [nTPM]":"156.5","Cell RNA - RT4 [nTPM]":"225.2","Cell RNA - SCLC-21H [nTPM]":"247.7","Cell RNA - SH-SY5Y [nTPM]":"350.8","Cell RNA - SiHa [nTPM]":"227.1","Cell RNA - SK-BR-3 [nTPM]":"196.3","Cell RNA - SK-MEL-30 [nTPM]":"120.4","Cell RNA - SuSa [nTPM]":"154.0","Cell RNA - T-47d [nTPM]":"238.8","Cell RNA - THP-1 [nTPM]":"301.6","Cell RNA - TIME [nTPM]":"187.9","Cell RNA - U-138 MG [nTPM]":"206.9","Cell RNA - U-2 OS [nTPM]":"271.3","Cell RNA - U-2197 [nTPM]":"139.4","Cell RNA - U-251 MG [nTPM]":"330.0","Cell RNA - U-266\/70 [nTPM]":"278.2","Cell RNA - U-266\/84 [nTPM]":"219.2","Cell RNA - U-698 [nTPM]":"552.9","Cell RNA - U-87 MG [nTPM]":"187.3","Cell RNA - U-937 [nTPM]":"318.9","Cell RNA - WM-115 [nTPM]":"177.1","Blood RNA - basophil [nTPM]":"2.5","Blood RNA - classical monocyte [nTPM]":"40.9","Blood RNA - eosinophil [nTPM]":"10.0","Blood RNA - gdT-cell [nTPM]":"26.0","Blood RNA - intermediate monocyte [nTPM]":"53.3","Blood RNA - MAIT T-cell [nTPM]":"26.0","Blood RNA - memory B-cell [nTPM]":"23.5","Blood RNA - memory CD4 T-cell [nTPM]":"17.7","Blood RNA - memory CD8 T-cell [nTPM]":"26.7","Blood RNA - myeloid DC [nTPM]":"67.0","Blood RNA - naive B-cell [nTPM]":"19.6","Blood RNA - naive CD4 T-cell [nTPM]":"20.1","Blood RNA - naive CD8 T-cell [nTPM]":"19.4","Blood RNA - neutrophil [nTPM]":"4.4","Blood RNA - NK-cell [nTPM]":"35.6","Blood RNA - non-classical monocyte [nTPM]":"33.6","Blood RNA - plasmacytoid DC [nTPM]":"49.2","Blood RNA - T-reg [nTPM]":"24.0","Blood RNA - total PBMC [nTPM]":"33.0","Brain RNA - amygdala [nTPM]":"27.8","Brain RNA - basal ganglia [nTPM]":"29.6","Brain RNA - cerebellum [nTPM]":"29.9","Brain RNA - cerebral cortex [nTPM]":"34.0","Brain RNA - hippocampal formation [nTPM]":"29.2","Brain RNA - hypothalamus [nTPM]":"32.9","Brain RNA - medulla oblongata [nTPM]":"30.8","Brain RNA - midbrain [nTPM]":"28.5","Brain RNA - pons [nTPM]":"30.3","Brain RNA - spinal cord [nTPM]":"31.3","Brain RNA - thalamus [nTPM]":"30.0","Brain RNA - white matter [nTPM]":"36.0","Single Cell Type RNA - Adipocytes [nTPM]":"271.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"118.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"105.6","Single Cell Type RNA - Astrocytes [nTPM]":"57.5","Single Cell Type RNA - B-cells [nTPM]":"396.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"460.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"439.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"205.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"540.1","Single Cell Type RNA - Bipolar cells [nTPM]":"151.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"291.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"277.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"86.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"148.7","Single Cell Type RNA - Club cells [nTPM]":"141.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"88.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"91.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"339.4","Single Cell Type RNA - dendritic cells [nTPM]":"548.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"233.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"156.5","Single Cell Type RNA - Ductal cells [nTPM]":"199.1","Single Cell Type RNA - Early spermatids [nTPM]":"203.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"176.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"181.9","Single Cell Type RNA - Endothelial cells [nTPM]":"204.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"266.3","Single Cell Type RNA - Erythroid cells [nTPM]":"366.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"51.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"157.3","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"579.7","Single Cell Type RNA - Fibroblasts [nTPM]":"233.9","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"196.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"257.4","Single Cell Type RNA - granulocytes [nTPM]":"218.4","Single Cell Type RNA - Granulosa cells [nTPM]":"241.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"116.7","Single Cell Type RNA - Hepatocytes [nTPM]":"125.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"251.3","Single Cell Type RNA - Horizontal cells [nTPM]":"99.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"55.4","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"246.9","Single Cell Type RNA - Ionocytes [nTPM]":"132.2","Single Cell Type RNA - Kupffer cells [nTPM]":"143.7","Single Cell Type RNA - Langerhans cells [nTPM]":"480.4","Single Cell Type RNA - Late spermatids [nTPM]":"162.0","Single Cell Type RNA - Leydig cells [nTPM]":"159.1","Single Cell Type RNA - Macrophages [nTPM]":"273.5","Single Cell Type RNA - Melanocytes [nTPM]":"282.8","Single Cell Type RNA - Microglial cells [nTPM]":"63.7","Single Cell Type RNA - monocytes [nTPM]":"226.9","Single Cell Type RNA - Muller glia cells [nTPM]":"153.3","Single Cell Type RNA - NK-cells [nTPM]":"196.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"55.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"87.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"189.0","Single Cell Type RNA - Paneth cells [nTPM]":"288.7","Single Cell Type RNA - Peritubular cells [nTPM]":"127.5","Single Cell Type RNA - Plasma cells [nTPM]":"492.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"384.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"250.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"128.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"97.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"188.9","Single Cell Type RNA - Sertoli cells [nTPM]":"118.3","Single Cell Type RNA - Skeletal myocytes [nTPM]":"286.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"242.1","Single Cell Type RNA - Spermatocytes [nTPM]":"272.3","Single Cell Type RNA - Spermatogonia [nTPM]":"296.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"489.5","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"443.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"316.0","Single Cell Type RNA - T-cells [nTPM]":"469.1","Single Cell Type RNA - Theca cells [nTPM]":"185.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"329.4","Single Cell Type RNA - Urothelial cells [nTPM]":"459.4"},{"Gene":"SSX1","Gene synonym":["CT5.1"],"Ensembl":"ENSG00000126752","Gene description":"SSX family member 1","Uniprot":["Q16384"],"Chromosome":"X","Position":"48255392-48267444","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"17","RNA tissue specific nTPM":{"testis":"6.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatocytes":"24.2","Spermatogonia":"30.2"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"liver cancer":"7.9"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"12","RNA cell line specific nTPM":{"Daudi":"66.1","Karpas-707":"90.5","U-2197":"22.7"},"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045683","HPA071685"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 78: Testis - Spermatogenesis","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA045683":"AB_2679418","HPA071685":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.25e-1"},"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.51e-3"},"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.36e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-3"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.38e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.94e-2"},"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.4","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.4","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.1","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.1","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.1","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.1","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"6.8","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"66.1","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"1.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.1","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.5","Cell RNA - Karpas-707 [nTPM]":"90.5","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.2","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.2","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.3","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.2","Cell RNA - U-2197 [nTPM]":"22.7","Cell RNA - U-251 MG [nTPM]":"0.1","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"4.8","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"5.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.1","Blood RNA - basophil [nTPM]":"0.1","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.4","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.1","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"1.4","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"24.2","Single Cell Type RNA - Spermatogonia [nTPM]":"30.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"SSX2","Gene synonym":["CT5.2a","HD21","HOM-MEL-40","MGC119055","MGC15364","MGC3884","SSX"],"Ensembl":"ENSG00000241476","Gene description":"SSX family member 2","Uniprot":["Q16385"],"Chromosome":"X","Position":"52696896-52707189","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"59","RNA tissue specific nTPM":{"testis":"15.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in single","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Spermatogonia":"2.9"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA045683","HPA071685"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Testis - Spermatogenesis","Cell line expression cluster":null,"Single cell expression cluster":"Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis","Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA045683":"AB_2679418","HPA071685":null},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":null,"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":null,"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":null,"Pathology prognostics - Ovarian cancer":null,"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":null,"Pathology prognostics - Testis cancer":null,"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":null,"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.1","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"15.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.2","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.1","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.0","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.1","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.1","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.0","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"STAT3","Gene synonym":["APRF"],"Ensembl":"ENSG00000168610","Gene description":"Signal transducer and activator of transcription 3","Uniprot":["P40763"],"Chromosome":"17","Position":"42313324-42388540","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Diabetes mellitus","Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001671","CAB003859","HPA058603","CAB068241","CAB068242"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"55000","Blood expression cluster":"Cluster 9: Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 46: Photoreceptor cells - Phototransduction","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB003859":"AB_347629","CAB068241":"AB_2665663","CAB068242":"AB_2665662","HPA001671":"AB_1080102","HPA058603":"AB_2683772"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.23e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.91e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.59e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.78e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.26e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.32e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.77e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.47e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.75e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.63e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.61e-1"},"Tissue RNA - adipose tissue [nTPM]":"105.6","Tissue RNA - adrenal gland [nTPM]":"68.1","Tissue RNA - amygdala [nTPM]":"32.4","Tissue RNA - appendix [nTPM]":"78.5","Tissue RNA - basal ganglia [nTPM]":"34.5","Tissue RNA - bone marrow [nTPM]":"63.2","Tissue RNA - breast [nTPM]":"84.4","Tissue RNA - cerebellum [nTPM]":"38.7","Tissue RNA - cerebral cortex [nTPM]":"30.2","Tissue RNA - cervix [nTPM]":"62.6","Tissue RNA - choroid plexus [nTPM]":"32.4","Tissue RNA - colon [nTPM]":"76.9","Tissue RNA - duodenum [nTPM]":"45.9","Tissue RNA - endometrium 1 [nTPM]":"71.6","Tissue RNA - epididymis [nTPM]":"28.2","Tissue RNA - esophagus [nTPM]":"81.6","Tissue RNA - fallopian tube [nTPM]":"74.0","Tissue RNA - gallbladder [nTPM]":"71.7","Tissue RNA - heart muscle [nTPM]":"101.2","Tissue RNA - hippocampal formation [nTPM]":"28.6","Tissue RNA - hypothalamus [nTPM]":"44.6","Tissue RNA - kidney [nTPM]":"77.2","Tissue RNA - liver [nTPM]":"143.1","Tissue RNA - lung [nTPM]":"106.0","Tissue RNA - lymph node [nTPM]":"55.3","Tissue RNA - medulla oblongata [nTPM]":"48.4","Tissue RNA - midbrain [nTPM]":"40.7","Tissue RNA - ovary [nTPM]":"65.4","Tissue RNA - pancreas [nTPM]":"67.3","Tissue RNA - parathyroid gland [nTPM]":"35.3","Tissue RNA - pituitary gland [nTPM]":"53.3","Tissue RNA - placenta [nTPM]":"55.6","Tissue RNA - pons [nTPM]":"43.4","Tissue RNA - prostate [nTPM]":"62.9","Tissue RNA - rectum [nTPM]":"46.5","Tissue RNA - retina [nTPM]":"29.9","Tissue RNA - salivary gland [nTPM]":"63.5","Tissue RNA - seminal vesicle [nTPM]":"48.2","Tissue RNA - skeletal muscle [nTPM]":"123.9","Tissue RNA - skin 1 [nTPM]":"66.8","Tissue RNA - small intestine [nTPM]":"68.1","Tissue RNA - smooth muscle [nTPM]":"72.1","Tissue RNA - spinal cord [nTPM]":"43.9","Tissue RNA - spleen [nTPM]":"68.0","Tissue RNA - stomach 1 [nTPM]":"62.3","Tissue RNA - testis [nTPM]":"24.6","Tissue RNA - thalamus [nTPM]":"43.0","Tissue RNA - thymus [nTPM]":"50.5","Tissue RNA - thyroid gland [nTPM]":"61.9","Tissue RNA - tongue [nTPM]":"92.1","Tissue RNA - tonsil [nTPM]":"65.2","Tissue RNA - urinary bladder [nTPM]":"88.6","Tissue RNA - vagina [nTPM]":"64.3","Tissue RNA - white matter [nTPM]":"43.1","Cell RNA - A-431 [nTPM]":"61.5","Cell RNA - A549 [nTPM]":"116.0","Cell RNA - AF22 [nTPM]":"47.4","Cell RNA - AN3-CA [nTPM]":"48.2","Cell RNA - ASC diff [nTPM]":"103.7","Cell RNA - ASC TERT1 [nTPM]":"97.6","Cell RNA - BEWO [nTPM]":"35.4","Cell RNA - BJ [nTPM]":"66.5","Cell RNA - BJ hTERT+ [nTPM]":"89.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"59.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"58.3","Cell RNA - CACO-2 [nTPM]":"30.3","Cell RNA - CAPAN-2 [nTPM]":"55.8","Cell RNA - Daudi [nTPM]":"18.5","Cell RNA - EFO-21 [nTPM]":"68.2","Cell RNA - fHDF\/TERT166 [nTPM]":"71.2","Cell RNA - GAMG [nTPM]":"90.3","Cell RNA - HaCaT [nTPM]":"89.2","Cell RNA - HAP1 [nTPM]":"45.8","Cell RNA - HBEC3-KT [nTPM]":"72.6","Cell RNA - HBF TERT88 [nTPM]":"47.7","Cell RNA - HDLM-2 [nTPM]":"160.6","Cell RNA - HEK 293 [nTPM]":"31.4","Cell RNA - HEL [nTPM]":"131.2","Cell RNA - HeLa [nTPM]":"60.4","Cell RNA - Hep G2 [nTPM]":"62.4","Cell RNA - HHSteC [nTPM]":"77.3","Cell RNA - HL-60 [nTPM]":"31.8","Cell RNA - HMC-1 [nTPM]":"79.0","Cell RNA - HSkMC [nTPM]":"152.1","Cell RNA - hTCEpi [nTPM]":"69.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"47.4","Cell RNA - hTERT-HME1 [nTPM]":"68.9","Cell RNA - hTERT-RPE1 [nTPM]":"62.2","Cell RNA - HUVEC TERT2 [nTPM]":"81.1","Cell RNA - JURKAT [nTPM]":"33.4","Cell RNA - K-562 [nTPM]":"80.1","Cell RNA - Karpas-707 [nTPM]":"56.4","Cell RNA - LHCN-M2 [nTPM]":"40.1","Cell RNA - MCF7 [nTPM]":"43.8","Cell RNA - MOLT-4 [nTPM]":"118.7","Cell RNA - NB-4 [nTPM]":"31.3","Cell RNA - NTERA-2 [nTPM]":"28.5","Cell RNA - OE19 [nTPM]":"63.4","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"26.6","Cell RNA - RH-30 [nTPM]":"133.8","Cell RNA - RPMI-8226 [nTPM]":"28.1","Cell RNA - RPTEC TERT1 [nTPM]":"91.3","Cell RNA - RT4 [nTPM]":"77.2","Cell RNA - SCLC-21H [nTPM]":"45.2","Cell RNA - SH-SY5Y [nTPM]":"29.8","Cell RNA - SiHa [nTPM]":"81.4","Cell RNA - SK-BR-3 [nTPM]":"184.9","Cell RNA - SK-MEL-30 [nTPM]":"29.2","Cell RNA - SuSa [nTPM]":"57.2","Cell RNA - T-47d [nTPM]":"100.5","Cell RNA - THP-1 [nTPM]":"49.1","Cell RNA - TIME [nTPM]":"68.7","Cell RNA - U-138 MG [nTPM]":"88.9","Cell RNA - U-2 OS [nTPM]":"44.9","Cell RNA - U-2197 [nTPM]":"54.8","Cell RNA - U-251 MG [nTPM]":"56.5","Cell RNA - U-266\/70 [nTPM]":"82.9","Cell RNA - U-266\/84 [nTPM]":"75.3","Cell RNA - U-698 [nTPM]":"16.4","Cell RNA - U-87 MG [nTPM]":"56.1","Cell RNA - U-937 [nTPM]":"32.8","Cell RNA - WM-115 [nTPM]":"41.6","Blood RNA - basophil [nTPM]":"121.1","Blood RNA - classical monocyte [nTPM]":"78.4","Blood RNA - eosinophil [nTPM]":"100.0","Blood RNA - gdT-cell [nTPM]":"79.5","Blood RNA - intermediate monocyte [nTPM]":"79.9","Blood RNA - MAIT T-cell [nTPM]":"64.4","Blood RNA - memory B-cell [nTPM]":"40.2","Blood RNA - memory CD4 T-cell [nTPM]":"57.5","Blood RNA - memory CD8 T-cell [nTPM]":"62.6","Blood RNA - myeloid DC [nTPM]":"54.3","Blood RNA - naive B-cell [nTPM]":"36.6","Blood RNA - naive CD4 T-cell [nTPM]":"58.7","Blood RNA - naive CD8 T-cell [nTPM]":"56.5","Blood RNA - neutrophil [nTPM]":"262.6","Blood RNA - NK-cell [nTPM]":"58.3","Blood RNA - non-classical monocyte [nTPM]":"80.8","Blood RNA - plasmacytoid DC [nTPM]":"29.3","Blood RNA - T-reg [nTPM]":"47.9","Blood RNA - total PBMC [nTPM]":"124.5","Brain RNA - amygdala [nTPM]":"32.4","Brain RNA - basal ganglia [nTPM]":"34.5","Brain RNA - cerebellum [nTPM]":"38.7","Brain RNA - cerebral cortex [nTPM]":"30.2","Brain RNA - hippocampal formation [nTPM]":"28.6","Brain RNA - hypothalamus [nTPM]":"44.6","Brain RNA - medulla oblongata [nTPM]":"48.4","Brain RNA - midbrain [nTPM]":"40.7","Brain RNA - pons [nTPM]":"43.4","Brain RNA - spinal cord [nTPM]":"43.9","Brain RNA - thalamus [nTPM]":"43.0","Brain RNA - white matter [nTPM]":"43.1","Single Cell Type RNA - Adipocytes [nTPM]":"216.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"93.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"173.7","Single Cell Type RNA - Astrocytes [nTPM]":"46.0","Single Cell Type RNA - B-cells [nTPM]":"111.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"129.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"76.8","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"138.3","Single Cell Type RNA - Bipolar cells [nTPM]":"92.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"147.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"113.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"59.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"103.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"134.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"281.5","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"25.2","Single Cell Type RNA - dendritic cells [nTPM]":"115.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"148.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"83.2","Single Cell Type RNA - Early spermatids [nTPM]":"33.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"129.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"187.0","Single Cell Type RNA - Endothelial cells [nTPM]":"164.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"124.0","Single Cell Type RNA - Erythroid cells [nTPM]":"54.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"24.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"96.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"38.2","Single Cell Type RNA - Fibroblasts [nTPM]":"154.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"109.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"153.9","Single Cell Type RNA - granulocytes [nTPM]":"142.0","Single Cell Type RNA - Granulosa cells [nTPM]":"86.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"115.3","Single Cell Type RNA - Hepatocytes [nTPM]":"115.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"69.1","Single Cell Type RNA - Horizontal cells [nTPM]":"25.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"35.8","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"97.8","Single Cell Type RNA - Ionocytes [nTPM]":"69.2","Single Cell Type RNA - Kupffer cells [nTPM]":"71.0","Single Cell Type RNA - Langerhans cells [nTPM]":"121.7","Single Cell Type RNA - Late spermatids [nTPM]":"13.7","Single Cell Type RNA - Leydig cells [nTPM]":"71.7","Single Cell Type RNA - Macrophages [nTPM]":"111.7","Single Cell Type RNA - Melanocytes [nTPM]":"72.9","Single Cell Type RNA - Microglial cells [nTPM]":"51.5","Single Cell Type RNA - monocytes [nTPM]":"94.1","Single Cell Type RNA - Muller glia cells [nTPM]":"131.3","Single Cell Type RNA - NK-cells [nTPM]":"78.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"30.7","Single Cell Type RNA - Oligodendrocytes [nTPM]":"41.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"82.9","Single Cell Type RNA - Paneth cells [nTPM]":"94.5","Single Cell Type RNA - Peritubular cells [nTPM]":"60.9","Single Cell Type RNA - Plasma cells [nTPM]":"104.6","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"147.9","Single Cell Type RNA - Proximal enterocytes [nTPM]":"206.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"46.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"88.5","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"406.7","Single Cell Type RNA - Sertoli cells [nTPM]":"65.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"189.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"169.7","Single Cell Type RNA - Spermatocytes [nTPM]":"31.5","Single Cell Type RNA - Spermatogonia [nTPM]":"15.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"93.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"160.1","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"31.2","Single Cell Type RNA - T-cells [nTPM]":"170.2","Single Cell Type RNA - Theca cells [nTPM]":"102.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"117.5","Single Cell Type RNA - Urothelial cells [nTPM]":"90.6"},{"Gene":"STK11","Gene synonym":["LKB1","PJS"],"Ensembl":"ENSG00000118046","Gene description":"Serine\/threonine kinase 11","Uniprot":["Q15831"],"Chromosome":"19","Position":"1177558-1228431","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Autophagy","Cell cycle","Differentiation","DNA damage","Spermatogenesis"],"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"154.9","Late spermatids":"338.7"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"9.9"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB016231","HPA017254","CAB022105","HPA067481"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 19: HEK293 & PC-3 - Transcription regulation","Single cell expression cluster":"Cluster 31: Spermatids - Spermatogenesis","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB016231":"AB_627890","CAB022105":null,"HPA017254":"AB_1852924","HPA067481":"AB_2685847"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.60e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.00e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"3.69e-5"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.04e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.96e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.11e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.95e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.70e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.54e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.31e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.12e-3"},"Tissue RNA - adipose tissue [nTPM]":"32.1","Tissue RNA - adrenal gland [nTPM]":"44.2","Tissue RNA - amygdala [nTPM]":"18.8","Tissue RNA - appendix [nTPM]":"18.2","Tissue RNA - basal ganglia [nTPM]":"15.5","Tissue RNA - bone marrow [nTPM]":"34.1","Tissue RNA - breast [nTPM]":"32.3","Tissue RNA - cerebellum [nTPM]":"24.8","Tissue RNA - cerebral cortex [nTPM]":"23.5","Tissue RNA - cervix [nTPM]":"35.4","Tissue RNA - choroid plexus [nTPM]":"24.7","Tissue RNA - colon [nTPM]":"38.7","Tissue RNA - duodenum [nTPM]":"25.6","Tissue RNA - endometrium 1 [nTPM]":"33.6","Tissue RNA - epididymis [nTPM]":"5.5","Tissue RNA - esophagus [nTPM]":"39.7","Tissue RNA - fallopian tube [nTPM]":"34.9","Tissue RNA - gallbladder [nTPM]":"11.8","Tissue RNA - heart muscle [nTPM]":"48.4","Tissue RNA - hippocampal formation [nTPM]":"18.3","Tissue RNA - hypothalamus [nTPM]":"14.7","Tissue RNA - kidney [nTPM]":"36.4","Tissue RNA - liver [nTPM]":"45.5","Tissue RNA - lung [nTPM]":"30.5","Tissue RNA - lymph node [nTPM]":"20.5","Tissue RNA - medulla oblongata [nTPM]":"19.2","Tissue RNA - midbrain [nTPM]":"19.4","Tissue RNA - ovary [nTPM]":"37.9","Tissue RNA - pancreas [nTPM]":"34.2","Tissue RNA - parathyroid gland [nTPM]":"16.1","Tissue RNA - pituitary gland [nTPM]":"36.8","Tissue RNA - placenta [nTPM]":"12.6","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"39.3","Tissue RNA - rectum [nTPM]":"7.7","Tissue RNA - retina [nTPM]":"5.7","Tissue RNA - salivary gland [nTPM]":"29.7","Tissue RNA - seminal vesicle [nTPM]":"16.1","Tissue RNA - skeletal muscle [nTPM]":"108.2","Tissue RNA - skin 1 [nTPM]":"40.2","Tissue RNA - small intestine [nTPM]":"37.7","Tissue RNA - smooth muscle [nTPM]":"9.6","Tissue RNA - spinal cord [nTPM]":"16.3","Tissue RNA - spleen [nTPM]":"48.3","Tissue RNA - stomach 1 [nTPM]":"38.1","Tissue RNA - testis [nTPM]":"102.4","Tissue RNA - thalamus [nTPM]":"17.6","Tissue RNA - thymus [nTPM]":"15.0","Tissue RNA - thyroid gland [nTPM]":"34.3","Tissue RNA - tongue [nTPM]":"27.7","Tissue RNA - tonsil [nTPM]":"12.9","Tissue RNA - urinary bladder [nTPM]":"34.4","Tissue RNA - vagina [nTPM]":"35.0","Tissue RNA - white matter [nTPM]":"14.9","Cell RNA - A-431 [nTPM]":"50.0","Cell RNA - A549 [nTPM]":"25.8","Cell RNA - AF22 [nTPM]":"19.9","Cell RNA - AN3-CA [nTPM]":"35.9","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"17.0","Cell RNA - BEWO [nTPM]":"35.5","Cell RNA - BJ [nTPM]":"24.0","Cell RNA - BJ hTERT+ [nTPM]":"27.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"25.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"25.4","Cell RNA - CACO-2 [nTPM]":"22.5","Cell RNA - CAPAN-2 [nTPM]":"37.1","Cell RNA - Daudi [nTPM]":"31.9","Cell RNA - EFO-21 [nTPM]":"24.8","Cell RNA - fHDF\/TERT166 [nTPM]":"27.8","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"32.3","Cell RNA - HAP1 [nTPM]":"20.1","Cell RNA - HBEC3-KT [nTPM]":"41.9","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"60.2","Cell RNA - HEK 293 [nTPM]":"37.8","Cell RNA - HEL [nTPM]":"34.8","Cell RNA - HeLa [nTPM]":"1.7","Cell RNA - Hep G2 [nTPM]":"26.4","Cell RNA - HHSteC [nTPM]":"38.1","Cell RNA - HL-60 [nTPM]":"36.6","Cell RNA - HMC-1 [nTPM]":"53.5","Cell RNA - HSkMC [nTPM]":"30.5","Cell RNA - hTCEpi [nTPM]":"28.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"19.4","Cell RNA - hTERT-HME1 [nTPM]":"29.2","Cell RNA - hTERT-RPE1 [nTPM]":"22.3","Cell RNA - HUVEC TERT2 [nTPM]":"25.2","Cell RNA - JURKAT [nTPM]":"28.1","Cell RNA - K-562 [nTPM]":"63.1","Cell RNA - Karpas-707 [nTPM]":"51.1","Cell RNA - LHCN-M2 [nTPM]":"13.9","Cell RNA - MCF7 [nTPM]":"39.3","Cell RNA - MOLT-4 [nTPM]":"31.9","Cell RNA - NB-4 [nTPM]":"27.7","Cell RNA - NTERA-2 [nTPM]":"33.0","Cell RNA - OE19 [nTPM]":"19.6","Cell RNA - PC-3 [nTPM]":"25.1","Cell RNA - REH [nTPM]":"50.0","Cell RNA - RH-30 [nTPM]":"20.0","Cell RNA - RPMI-8226 [nTPM]":"36.1","Cell RNA - RPTEC TERT1 [nTPM]":"21.1","Cell RNA - RT4 [nTPM]":"39.7","Cell RNA - SCLC-21H [nTPM]":"39.8","Cell RNA - SH-SY5Y [nTPM]":"26.6","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"19.7","Cell RNA - SK-MEL-30 [nTPM]":"24.2","Cell RNA - SuSa [nTPM]":"11.4","Cell RNA - T-47d [nTPM]":"30.3","Cell RNA - THP-1 [nTPM]":"55.2","Cell RNA - TIME [nTPM]":"33.7","Cell RNA - U-138 MG [nTPM]":"24.6","Cell RNA - U-2 OS [nTPM]":"25.0","Cell RNA - U-2197 [nTPM]":"45.2","Cell RNA - U-251 MG [nTPM]":"38.7","Cell RNA - U-266\/70 [nTPM]":"85.3","Cell RNA - U-266\/84 [nTPM]":"38.1","Cell RNA - U-698 [nTPM]":"25.7","Cell RNA - U-87 MG [nTPM]":"22.6","Cell RNA - U-937 [nTPM]":"48.1","Cell RNA - WM-115 [nTPM]":"25.5","Blood RNA - basophil [nTPM]":"1.7","Blood RNA - classical monocyte [nTPM]":"3.3","Blood RNA - eosinophil [nTPM]":"3.9","Blood RNA - gdT-cell [nTPM]":"0.4","Blood RNA - intermediate monocyte [nTPM]":"5.5","Blood RNA - MAIT T-cell [nTPM]":"0.3","Blood RNA - memory B-cell [nTPM]":"2.3","Blood RNA - memory CD4 T-cell [nTPM]":"0.8","Blood RNA - memory CD8 T-cell [nTPM]":"1.4","Blood RNA - myeloid DC [nTPM]":"1.6","Blood RNA - naive B-cell [nTPM]":"0.7","Blood RNA - naive CD4 T-cell [nTPM]":"0.7","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"9.9","Blood RNA - NK-cell [nTPM]":"1.4","Blood RNA - non-classical monocyte [nTPM]":"5.7","Blood RNA - plasmacytoid DC [nTPM]":"0.8","Blood RNA - T-reg [nTPM]":"0.6","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"18.8","Brain RNA - basal ganglia [nTPM]":"15.5","Brain RNA - cerebellum [nTPM]":"24.8","Brain RNA - cerebral cortex [nTPM]":"23.5","Brain RNA - hippocampal formation [nTPM]":"18.3","Brain RNA - hypothalamus [nTPM]":"14.7","Brain RNA - medulla oblongata [nTPM]":"19.2","Brain RNA - midbrain [nTPM]":"19.4","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"16.3","Brain RNA - thalamus [nTPM]":"17.6","Brain RNA - white matter [nTPM]":"14.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"13.7","Single Cell Type RNA - Astrocytes [nTPM]":"12.7","Single Cell Type RNA - B-cells [nTPM]":"10.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"9.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"9.6","Single Cell Type RNA - Bipolar cells [nTPM]":"25.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"22.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"18.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"13.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"9.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"23.9","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.5","Single Cell Type RNA - dendritic cells [nTPM]":"20.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"44.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"9.4","Single Cell Type RNA - Early spermatids [nTPM]":"154.9","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.1","Single Cell Type RNA - Endothelial cells [nTPM]":"15.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"15.0","Single Cell Type RNA - Erythroid cells [nTPM]":"27.3","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.3","Single Cell Type RNA - Fibroblasts [nTPM]":"13.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"17.8","Single Cell Type RNA - granulocytes [nTPM]":"2.5","Single Cell Type RNA - Granulosa cells [nTPM]":"80.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"15.4","Single Cell Type RNA - Hepatocytes [nTPM]":"31.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"15.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"33.1","Single Cell Type RNA - Ionocytes [nTPM]":"6.1","Single Cell Type RNA - Kupffer cells [nTPM]":"18.3","Single Cell Type RNA - Langerhans cells [nTPM]":"26.4","Single Cell Type RNA - Late spermatids [nTPM]":"338.7","Single Cell Type RNA - Leydig cells [nTPM]":"24.5","Single Cell Type RNA - Macrophages [nTPM]":"20.7","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"20.4","Single Cell Type RNA - Muller glia cells [nTPM]":"21.2","Single Cell Type RNA - NK-cells [nTPM]":"9.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.5","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"16.7","Single Cell Type RNA - Paneth cells [nTPM]":"29.3","Single Cell Type RNA - Peritubular cells [nTPM]":"20.7","Single Cell Type RNA - Plasma cells [nTPM]":"10.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"27.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"11.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"21.0","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"23.7","Single Cell Type RNA - Spermatocytes [nTPM]":"85.5","Single Cell Type RNA - Spermatogonia [nTPM]":"20.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"14.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"15.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"8.8","Single Cell Type RNA - T-cells [nTPM]":"16.6","Single Cell Type RNA - Theca cells [nTPM]":"45.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"35.4","Single Cell Type RNA - Urothelial cells [nTPM]":"12.6"},{"Gene":"SUFU","Gene synonym":["PRO1280","SUFUH","SUFUXL"],"Ensembl":"ENSG00000107882","Gene description":"SUFU negative regulator of hedgehog signaling","Uniprot":["Q9UMX1"],"Chromosome":"10","Position":"102503972-102633535","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Developmental protein"],"Disease involvement":["Cancer-related genes","Ciliopathy","Disease variant","Joubert syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"129.2","Late spermatids":"115.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA008700"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 23: AN3-CA - Transcription regulation","Single cell expression cluster":"Cluster 34: Spermatids - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA008700":"AB_1080125"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.55e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.14e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.69e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.68e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.69e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.15e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.60e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.13e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.72e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.44e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.10e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.82e-3"},"Tissue RNA - adipose tissue [nTPM]":"6.6","Tissue RNA - adrenal gland [nTPM]":"7.2","Tissue RNA - amygdala [nTPM]":"8.8","Tissue RNA - appendix [nTPM]":"7.1","Tissue RNA - basal ganglia [nTPM]":"8.5","Tissue RNA - bone marrow [nTPM]":"2.0","Tissue RNA - breast [nTPM]":"6.1","Tissue RNA - cerebellum [nTPM]":"8.9","Tissue RNA - cerebral cortex [nTPM]":"8.0","Tissue RNA - cervix [nTPM]":"8.6","Tissue RNA - choroid plexus [nTPM]":"5.5","Tissue RNA - colon [nTPM]":"6.8","Tissue RNA - duodenum [nTPM]":"3.9","Tissue RNA - endometrium 1 [nTPM]":"7.4","Tissue RNA - epididymis [nTPM]":"4.9","Tissue RNA - esophagus [nTPM]":"9.2","Tissue RNA - fallopian tube [nTPM]":"7.1","Tissue RNA - gallbladder [nTPM]":"6.6","Tissue RNA - heart muscle [nTPM]":"6.3","Tissue RNA - hippocampal formation [nTPM]":"7.8","Tissue RNA - hypothalamus [nTPM]":"7.3","Tissue RNA - kidney [nTPM]":"6.1","Tissue RNA - liver [nTPM]":"6.2","Tissue RNA - lung [nTPM]":"5.8","Tissue RNA - lymph node [nTPM]":"7.2","Tissue RNA - medulla oblongata [nTPM]":"8.3","Tissue RNA - midbrain [nTPM]":"8.2","Tissue RNA - ovary [nTPM]":"8.9","Tissue RNA - pancreas [nTPM]":"4.1","Tissue RNA - parathyroid gland [nTPM]":"11.1","Tissue RNA - pituitary gland [nTPM]":"4.3","Tissue RNA - placenta [nTPM]":"7.4","Tissue RNA - pons [nTPM]":"7.8","Tissue RNA - prostate [nTPM]":"8.5","Tissue RNA - rectum [nTPM]":"4.4","Tissue RNA - retina [nTPM]":"4.6","Tissue RNA - salivary gland [nTPM]":"7.1","Tissue RNA - seminal vesicle [nTPM]":"5.2","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"14.4","Tissue RNA - small intestine [nTPM]":"5.7","Tissue RNA - smooth muscle [nTPM]":"7.3","Tissue RNA - spinal cord [nTPM]":"6.7","Tissue RNA - spleen [nTPM]":"7.4","Tissue RNA - stomach 1 [nTPM]":"4.6","Tissue RNA - testis [nTPM]":"11.5","Tissue RNA - thalamus [nTPM]":"8.0","Tissue RNA - thymus [nTPM]":"7.8","Tissue RNA - thyroid gland [nTPM]":"3.4","Tissue RNA - tongue [nTPM]":"7.3","Tissue RNA - tonsil [nTPM]":"8.1","Tissue RNA - urinary bladder [nTPM]":"8.8","Tissue RNA - vagina [nTPM]":"9.2","Tissue RNA - white matter [nTPM]":"7.3","Cell RNA - A-431 [nTPM]":"8.7","Cell RNA - A549 [nTPM]":"9.1","Cell RNA - AF22 [nTPM]":"14.4","Cell RNA - AN3-CA [nTPM]":"20.8","Cell RNA - ASC diff [nTPM]":"14.5","Cell RNA - ASC TERT1 [nTPM]":"12.1","Cell RNA - BEWO [nTPM]":"7.0","Cell RNA - BJ [nTPM]":"8.8","Cell RNA - BJ hTERT+ [nTPM]":"17.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"12.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.3","Cell RNA - CACO-2 [nTPM]":"8.5","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"8.9","Cell RNA - EFO-21 [nTPM]":"24.5","Cell RNA - fHDF\/TERT166 [nTPM]":"9.9","Cell RNA - GAMG [nTPM]":"5.0","Cell RNA - HaCaT [nTPM]":"6.0","Cell RNA - HAP1 [nTPM]":"17.8","Cell RNA - HBEC3-KT [nTPM]":"9.8","Cell RNA - HBF TERT88 [nTPM]":"8.2","Cell RNA - HDLM-2 [nTPM]":"5.5","Cell RNA - HEK 293 [nTPM]":"13.8","Cell RNA - HEL [nTPM]":"21.2","Cell RNA - HeLa [nTPM]":"5.2","Cell RNA - Hep G2 [nTPM]":"8.0","Cell RNA - HHSteC [nTPM]":"6.9","Cell RNA - HL-60 [nTPM]":"7.7","Cell RNA - HMC-1 [nTPM]":"14.6","Cell RNA - HSkMC [nTPM]":"13.9","Cell RNA - hTCEpi [nTPM]":"7.5","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"9.3","Cell RNA - hTERT-HME1 [nTPM]":"7.5","Cell RNA - hTERT-RPE1 [nTPM]":"22.9","Cell RNA - HUVEC TERT2 [nTPM]":"16.3","Cell RNA - JURKAT [nTPM]":"8.5","Cell RNA - K-562 [nTPM]":"4.8","Cell RNA - Karpas-707 [nTPM]":"7.9","Cell RNA - LHCN-M2 [nTPM]":"7.8","Cell RNA - MCF7 [nTPM]":"7.2","Cell RNA - MOLT-4 [nTPM]":"14.8","Cell RNA - NB-4 [nTPM]":"11.6","Cell RNA - NTERA-2 [nTPM]":"4.1","Cell RNA - OE19 [nTPM]":"5.6","Cell RNA - PC-3 [nTPM]":"6.7","Cell RNA - REH [nTPM]":"15.8","Cell RNA - RH-30 [nTPM]":"15.5","Cell RNA - RPMI-8226 [nTPM]":"4.7","Cell RNA - RPTEC TERT1 [nTPM]":"8.3","Cell RNA - RT4 [nTPM]":"12.8","Cell RNA - SCLC-21H [nTPM]":"4.8","Cell RNA - SH-SY5Y [nTPM]":"7.8","Cell RNA - SiHa [nTPM]":"7.0","Cell RNA - SK-BR-3 [nTPM]":"6.4","Cell RNA - SK-MEL-30 [nTPM]":"8.1","Cell RNA - SuSa [nTPM]":"13.1","Cell RNA - T-47d [nTPM]":"14.2","Cell RNA - THP-1 [nTPM]":"5.0","Cell RNA - TIME [nTPM]":"18.1","Cell RNA - U-138 MG [nTPM]":"5.5","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"6.0","Cell RNA - U-251 MG [nTPM]":"9.8","Cell RNA - U-266\/70 [nTPM]":"6.4","Cell RNA - U-266\/84 [nTPM]":"4.5","Cell RNA - U-698 [nTPM]":"6.4","Cell RNA - U-87 MG [nTPM]":"6.9","Cell RNA - U-937 [nTPM]":"14.9","Cell RNA - WM-115 [nTPM]":"3.8","Blood RNA - basophil [nTPM]":"2.0","Blood RNA - classical monocyte [nTPM]":"2.0","Blood RNA - eosinophil [nTPM]":"2.9","Blood RNA - gdT-cell [nTPM]":"1.0","Blood RNA - intermediate monocyte [nTPM]":"2.4","Blood RNA - MAIT T-cell [nTPM]":"0.8","Blood RNA - memory B-cell [nTPM]":"0.9","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"1.1","Blood RNA - myeloid DC [nTPM]":"1.9","Blood RNA - naive B-cell [nTPM]":"0.8","Blood RNA - naive CD4 T-cell [nTPM]":"0.8","Blood RNA - naive CD8 T-cell [nTPM]":"1.0","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"1.1","Blood RNA - non-classical monocyte [nTPM]":"2.5","Blood RNA - plasmacytoid DC [nTPM]":"1.1","Blood RNA - T-reg [nTPM]":"0.8","Blood RNA - total PBMC [nTPM]":"1.4","Brain RNA - amygdala [nTPM]":"8.8","Brain RNA - basal ganglia [nTPM]":"8.5","Brain RNA - cerebellum [nTPM]":"8.9","Brain RNA - cerebral cortex [nTPM]":"8.0","Brain RNA - hippocampal formation [nTPM]":"7.8","Brain RNA - hypothalamus [nTPM]":"7.3","Brain RNA - medulla oblongata [nTPM]":"8.3","Brain RNA - midbrain [nTPM]":"8.2","Brain RNA - pons [nTPM]":"7.8","Brain RNA - spinal cord [nTPM]":"6.7","Brain RNA - thalamus [nTPM]":"8.0","Brain RNA - white matter [nTPM]":"7.3","Single Cell Type RNA - Adipocytes [nTPM]":"3.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"3.7","Single Cell Type RNA - Astrocytes [nTPM]":"28.7","Single Cell Type RNA - B-cells [nTPM]":"4.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"3.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"2.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"2.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"6.8","Single Cell Type RNA - Bipolar cells [nTPM]":"4.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"3.5","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"3.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"4.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"3.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"8.4","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"7.8","Single Cell Type RNA - dendritic cells [nTPM]":"3.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"3.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"4.4","Single Cell Type RNA - Early spermatids [nTPM]":"129.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"6.2","Single Cell Type RNA - Endothelial cells [nTPM]":"5.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"2.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"25.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"3.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"3.5","Single Cell Type RNA - Fibroblasts [nTPM]":"6.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"8.5","Single Cell Type RNA - granulocytes [nTPM]":"3.8","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"5.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"12.4","Single Cell Type RNA - Horizontal cells [nTPM]":"1.7","Single Cell Type RNA - Inhibitory neurons [nTPM]":"22.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"2.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"9.4","Single Cell Type RNA - Langerhans cells [nTPM]":"6.3","Single Cell Type RNA - Late spermatids [nTPM]":"115.9","Single Cell Type RNA - Leydig cells [nTPM]":"5.0","Single Cell Type RNA - Macrophages [nTPM]":"8.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"32.8","Single Cell Type RNA - monocytes [nTPM]":"7.8","Single Cell Type RNA - Muller glia cells [nTPM]":"2.7","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"17.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"16.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.1","Single Cell Type RNA - Paneth cells [nTPM]":"1.3","Single Cell Type RNA - Peritubular cells [nTPM]":"6.8","Single Cell Type RNA - Plasma cells [nTPM]":"4.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"2.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"5.7","Single Cell Type RNA - Proximal tubular cells [nTPM]":"5.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"4.8","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"3.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"4.5","Single Cell Type RNA - Spermatocytes [nTPM]":"8.7","Single Cell Type RNA - Spermatogonia [nTPM]":"5.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.0","Single Cell Type RNA - T-cells [nTPM]":"7.1","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.0","Single Cell Type RNA - Urothelial cells [nTPM]":"1.3"},{"Gene":"TAL1","Gene synonym":["bHLHa17","SCL","TCL5"],"Ensembl":"ENSG00000162367","Gene description":"TAL bHLH transcription factor 1, erythroid differentiation factor","Uniprot":["P17542"],"Chromosome":"1","Position":"47216290-47232220","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"29.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nTPM":{"Erythroid cells":"151.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"153.7","HMC-1":"70.6","HUVEC TERT2":"31.2","JURKAT":"60.0","K-562":"48.9","MOLT-4":"26.3","TIME":"34.4"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"midbrain":"14.3"},"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB017805","HPA047866","HPA073983"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Basophils - Unknown function","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 6: Erythroid cells - Oxygen transport","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB017805":null,"HPA047866":"AB_2680192","HPA073983":"AB_2732246"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.62e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.22e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.80e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.95e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.99e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.42e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.68e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.02e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.19e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.51e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-2"},"Tissue RNA - adipose tissue [nTPM]":"7.5","Tissue RNA - adrenal gland [nTPM]":"2.5","Tissue RNA - amygdala [nTPM]":"4.9","Tissue RNA - appendix [nTPM]":"1.0","Tissue RNA - basal ganglia [nTPM]":"4.5","Tissue RNA - bone marrow [nTPM]":"29.4","Tissue RNA - breast [nTPM]":"6.3","Tissue RNA - cerebellum [nTPM]":"4.7","Tissue RNA - cerebral cortex [nTPM]":"4.4","Tissue RNA - cervix [nTPM]":"2.9","Tissue RNA - choroid plexus [nTPM]":"3.0","Tissue RNA - colon [nTPM]":"2.1","Tissue RNA - duodenum [nTPM]":"0.8","Tissue RNA - endometrium 1 [nTPM]":"2.9","Tissue RNA - epididymis [nTPM]":"0.6","Tissue RNA - esophagus [nTPM]":"1.8","Tissue RNA - fallopian tube [nTPM]":"3.5","Tissue RNA - gallbladder [nTPM]":"2.3","Tissue RNA - heart muscle [nTPM]":"5.9","Tissue RNA - hippocampal formation [nTPM]":"4.6","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"4.4","Tissue RNA - liver [nTPM]":"1.5","Tissue RNA - lung [nTPM]":"13.0","Tissue RNA - lymph node [nTPM]":"1.4","Tissue RNA - medulla oblongata [nTPM]":"6.5","Tissue RNA - midbrain [nTPM]":"7.1","Tissue RNA - ovary [nTPM]":"1.2","Tissue RNA - pancreas [nTPM]":"0.9","Tissue RNA - parathyroid gland [nTPM]":"0.9","Tissue RNA - pituitary gland [nTPM]":"1.7","Tissue RNA - placenta [nTPM]":"6.9","Tissue RNA - pons [nTPM]":"6.8","Tissue RNA - prostate [nTPM]":"2.1","Tissue RNA - rectum [nTPM]":"1.3","Tissue RNA - retina [nTPM]":"0.2","Tissue RNA - salivary gland [nTPM]":"1.1","Tissue RNA - seminal vesicle [nTPM]":"0.8","Tissue RNA - skeletal muscle [nTPM]":"2.1","Tissue RNA - skin 1 [nTPM]":"1.7","Tissue RNA - small intestine [nTPM]":"3.1","Tissue RNA - smooth muscle [nTPM]":"2.7","Tissue RNA - spinal cord [nTPM]":"6.9","Tissue RNA - spleen [nTPM]":"7.1","Tissue RNA - stomach 1 [nTPM]":"1.8","Tissue RNA - testis [nTPM]":"0.9","Tissue RNA - thalamus [nTPM]":"6.4","Tissue RNA - thymus [nTPM]":"0.4","Tissue RNA - thyroid gland [nTPM]":"5.4","Tissue RNA - tongue [nTPM]":"2.5","Tissue RNA - tonsil [nTPM]":"0.7","Tissue RNA - urinary bladder [nTPM]":"2.4","Tissue RNA - vagina [nTPM]":"2.5","Tissue RNA - white matter [nTPM]":"6.8","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.1","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"2.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.1","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"10.6","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.2","Cell RNA - HEK 293 [nTPM]":"0.1","Cell RNA - HEL [nTPM]":"153.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"70.6","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"31.2","Cell RNA - JURKAT [nTPM]":"60.0","Cell RNA - K-562 [nTPM]":"48.9","Cell RNA - Karpas-707 [nTPM]":"0.1","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"26.3","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.3","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.3","Cell RNA - SK-BR-3 [nTPM]":"0.1","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"0.1","Cell RNA - TIME [nTPM]":"34.4","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.8","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.1","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.1","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.8","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.1","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"0.1","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.5","Brain RNA - amygdala [nTPM]":"4.9","Brain RNA - basal ganglia [nTPM]":"4.5","Brain RNA - cerebellum [nTPM]":"4.7","Brain RNA - cerebral cortex [nTPM]":"4.4","Brain RNA - hippocampal formation [nTPM]":"4.6","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"6.5","Brain RNA - midbrain [nTPM]":"7.1","Brain RNA - pons [nTPM]":"6.8","Brain RNA - spinal cord [nTPM]":"6.9","Brain RNA - thalamus [nTPM]":"6.4","Brain RNA - white matter [nTPM]":"6.8","Single Cell Type RNA - Adipocytes [nTPM]":"23.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"3.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"1.5","Single Cell Type RNA - Club cells [nTPM]":"1.3","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.1","Single Cell Type RNA - Early spermatids [nTPM]":"5.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.1","Single Cell Type RNA - Endothelial cells [nTPM]":"18.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"151.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.3","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"36.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.7","Single Cell Type RNA - Hepatocytes [nTPM]":"0.1","Single Cell Type RNA - Hofbauer cells [nTPM]":"10.6","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"1.6","Single Cell Type RNA - Langerhans cells [nTPM]":"1.5","Single Cell Type RNA - Late spermatids [nTPM]":"18.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"4.8","Single Cell Type RNA - Melanocytes [nTPM]":"1.8","Single Cell Type RNA - Microglial cells [nTPM]":"29.0","Single Cell Type RNA - monocytes [nTPM]":"0.8","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"1.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.1","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.4","Single Cell Type RNA - Spermatocytes [nTPM]":"1.3","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"1.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"2.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TCF3","Gene synonym":["bHLHb21","E2A","E47","ITF1","MGC129647","MGC129648","p75","VDIR"],"Ensembl":"ENSG00000071564","Gene description":"Transcription factor 3","Uniprot":["P15923"],"Chromosome":"19","Position":"1609290-1652615","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"REH":"467.3","U-698":"597.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB018351","HPA049808","HPA062476"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 27: U-698-M & Daudi - Adaptive immune response","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB018351":"AB_675504","HPA049808":"AB_2680892","HPA062476":"AB_2684775"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.82e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.74e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.91e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.25e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.46e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.07e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.99e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.35e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.42e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.29e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.53e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.87e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.88e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.07e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.05e-2"},"Tissue RNA - adipose tissue [nTPM]":"23.8","Tissue RNA - adrenal gland [nTPM]":"17.9","Tissue RNA - amygdala [nTPM]":"20.7","Tissue RNA - appendix [nTPM]":"49.2","Tissue RNA - basal ganglia [nTPM]":"20.0","Tissue RNA - bone marrow [nTPM]":"72.8","Tissue RNA - breast [nTPM]":"26.1","Tissue RNA - cerebellum [nTPM]":"18.1","Tissue RNA - cerebral cortex [nTPM]":"22.7","Tissue RNA - cervix [nTPM]":"33.4","Tissue RNA - choroid plexus [nTPM]":"21.9","Tissue RNA - colon [nTPM]":"32.3","Tissue RNA - duodenum [nTPM]":"35.5","Tissue RNA - endometrium 1 [nTPM]":"29.6","Tissue RNA - epididymis [nTPM]":"16.2","Tissue RNA - esophagus [nTPM]":"28.2","Tissue RNA - fallopian tube [nTPM]":"25.5","Tissue RNA - gallbladder [nTPM]":"19.8","Tissue RNA - heart muscle [nTPM]":"22.8","Tissue RNA - hippocampal formation [nTPM]":"19.1","Tissue RNA - hypothalamus [nTPM]":"17.8","Tissue RNA - kidney [nTPM]":"27.2","Tissue RNA - liver [nTPM]":"18.9","Tissue RNA - lung [nTPM]":"25.9","Tissue RNA - lymph node [nTPM]":"86.6","Tissue RNA - medulla oblongata [nTPM]":"22.0","Tissue RNA - midbrain [nTPM]":"19.3","Tissue RNA - ovary [nTPM]":"35.1","Tissue RNA - pancreas [nTPM]":"28.4","Tissue RNA - parathyroid gland [nTPM]":"10.2","Tissue RNA - pituitary gland [nTPM]":"26.2","Tissue RNA - placenta [nTPM]":"17.9","Tissue RNA - pons [nTPM]":"20.4","Tissue RNA - prostate [nTPM]":"27.3","Tissue RNA - rectum [nTPM]":"18.7","Tissue RNA - retina [nTPM]":"11.0","Tissue RNA - salivary gland [nTPM]":"26.4","Tissue RNA - seminal vesicle [nTPM]":"12.0","Tissue RNA - skeletal muscle [nTPM]":"19.5","Tissue RNA - skin 1 [nTPM]":"32.9","Tissue RNA - small intestine [nTPM]":"48.0","Tissue RNA - smooth muscle [nTPM]":"14.4","Tissue RNA - spinal cord [nTPM]":"18.3","Tissue RNA - spleen [nTPM]":"62.5","Tissue RNA - stomach 1 [nTPM]":"27.3","Tissue RNA - testis [nTPM]":"74.8","Tissue RNA - thalamus [nTPM]":"20.3","Tissue RNA - thymus [nTPM]":"68.4","Tissue RNA - thyroid gland [nTPM]":"31.6","Tissue RNA - tongue [nTPM]":"12.5","Tissue RNA - tonsil [nTPM]":"61.0","Tissue RNA - urinary bladder [nTPM]":"27.4","Tissue RNA - vagina [nTPM]":"27.4","Tissue RNA - white matter [nTPM]":"21.8","Cell RNA - A-431 [nTPM]":"83.6","Cell RNA - A549 [nTPM]":"48.6","Cell RNA - AF22 [nTPM]":"146.4","Cell RNA - AN3-CA [nTPM]":"139.8","Cell RNA - ASC diff [nTPM]":"18.6","Cell RNA - ASC TERT1 [nTPM]":"49.6","Cell RNA - BEWO [nTPM]":"50.4","Cell RNA - BJ [nTPM]":"51.9","Cell RNA - BJ hTERT+ [nTPM]":"48.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"67.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"60.6","Cell RNA - CACO-2 [nTPM]":"89.8","Cell RNA - CAPAN-2 [nTPM]":"68.7","Cell RNA - Daudi [nTPM]":"421.7","Cell RNA - EFO-21 [nTPM]":"53.5","Cell RNA - fHDF\/TERT166 [nTPM]":"50.1","Cell RNA - GAMG [nTPM]":"12.7","Cell RNA - HaCaT [nTPM]":"98.4","Cell RNA - HAP1 [nTPM]":"87.9","Cell RNA - HBEC3-KT [nTPM]":"69.2","Cell RNA - HBF TERT88 [nTPM]":"42.8","Cell RNA - HDLM-2 [nTPM]":"253.7","Cell RNA - HEK 293 [nTPM]":"52.4","Cell RNA - HEL [nTPM]":"43.2","Cell RNA - HeLa [nTPM]":"71.2","Cell RNA - Hep G2 [nTPM]":"115.2","Cell RNA - HHSteC [nTPM]":"44.8","Cell RNA - HL-60 [nTPM]":"105.7","Cell RNA - HMC-1 [nTPM]":"56.8","Cell RNA - HSkMC [nTPM]":"34.0","Cell RNA - hTCEpi [nTPM]":"75.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"52.4","Cell RNA - hTERT-HME1 [nTPM]":"39.2","Cell RNA - hTERT-RPE1 [nTPM]":"64.0","Cell RNA - HUVEC TERT2 [nTPM]":"82.5","Cell RNA - JURKAT [nTPM]":"176.1","Cell RNA - K-562 [nTPM]":"163.8","Cell RNA - Karpas-707 [nTPM]":"146.6","Cell RNA - LHCN-M2 [nTPM]":"46.0","Cell RNA - MCF7 [nTPM]":"158.2","Cell RNA - MOLT-4 [nTPM]":"301.1","Cell RNA - NB-4 [nTPM]":"107.8","Cell RNA - NTERA-2 [nTPM]":"187.1","Cell RNA - OE19 [nTPM]":"65.1","Cell RNA - PC-3 [nTPM]":"49.2","Cell RNA - REH [nTPM]":"467.3","Cell RNA - RH-30 [nTPM]":"61.7","Cell RNA - RPMI-8226 [nTPM]":"104.3","Cell RNA - RPTEC TERT1 [nTPM]":"46.5","Cell RNA - RT4 [nTPM]":"78.5","Cell RNA - SCLC-21H [nTPM]":"119.3","Cell RNA - SH-SY5Y [nTPM]":"175.7","Cell RNA - SiHa [nTPM]":"50.1","Cell RNA - SK-BR-3 [nTPM]":"55.9","Cell RNA - SK-MEL-30 [nTPM]":"70.8","Cell RNA - SuSa [nTPM]":"53.0","Cell RNA - T-47d [nTPM]":"63.8","Cell RNA - THP-1 [nTPM]":"191.7","Cell RNA - TIME [nTPM]":"103.2","Cell RNA - U-138 MG [nTPM]":"87.1","Cell RNA - U-2 OS [nTPM]":"90.5","Cell RNA - U-2197 [nTPM]":"116.0","Cell RNA - U-251 MG [nTPM]":"94.1","Cell RNA - U-266\/70 [nTPM]":"353.5","Cell RNA - U-266\/84 [nTPM]":"173.5","Cell RNA - U-698 [nTPM]":"597.2","Cell RNA - U-87 MG [nTPM]":"63.1","Cell RNA - U-937 [nTPM]":"140.3","Cell RNA - WM-115 [nTPM]":"80.1","Blood RNA - basophil [nTPM]":"3.3","Blood RNA - classical monocyte [nTPM]":"1.2","Blood RNA - eosinophil [nTPM]":"1.0","Blood RNA - gdT-cell [nTPM]":"3.6","Blood RNA - intermediate monocyte [nTPM]":"1.5","Blood RNA - MAIT T-cell [nTPM]":"3.6","Blood RNA - memory B-cell [nTPM]":"10.0","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"3.1","Blood RNA - myeloid DC [nTPM]":"2.8","Blood RNA - naive B-cell [nTPM]":"10.6","Blood RNA - naive CD4 T-cell [nTPM]":"2.8","Blood RNA - naive CD8 T-cell [nTPM]":"4.3","Blood RNA - neutrophil [nTPM]":"0.4","Blood RNA - NK-cell [nTPM]":"2.8","Blood RNA - non-classical monocyte [nTPM]":"3.2","Blood RNA - plasmacytoid DC [nTPM]":"12.9","Blood RNA - T-reg [nTPM]":"2.2","Blood RNA - total PBMC [nTPM]":"1.7","Brain RNA - amygdala [nTPM]":"20.7","Brain RNA - basal ganglia [nTPM]":"20.0","Brain RNA - cerebellum [nTPM]":"18.1","Brain RNA - cerebral cortex [nTPM]":"22.7","Brain RNA - hippocampal formation [nTPM]":"19.1","Brain RNA - hypothalamus [nTPM]":"17.8","Brain RNA - medulla oblongata [nTPM]":"22.0","Brain RNA - midbrain [nTPM]":"19.3","Brain RNA - pons [nTPM]":"20.4","Brain RNA - spinal cord [nTPM]":"18.3","Brain RNA - thalamus [nTPM]":"20.3","Brain RNA - white matter [nTPM]":"21.8","Single Cell Type RNA - Adipocytes [nTPM]":"17.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.1","Single Cell Type RNA - Astrocytes [nTPM]":"14.7","Single Cell Type RNA - B-cells [nTPM]":"33.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"13.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"5.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"10.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"4.6","Single Cell Type RNA - Bipolar cells [nTPM]":"12.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"16.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"10.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"10.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"4.3","Single Cell Type RNA - dendritic cells [nTPM]":"26.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.4","Single Cell Type RNA - Early spermatids [nTPM]":"8.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"9.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"20.4","Single Cell Type RNA - Endothelial cells [nTPM]":"13.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.2","Single Cell Type RNA - Erythroid cells [nTPM]":"32.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"3.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"8.9","Single Cell Type RNA - Fibroblasts [nTPM]":"12.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"16.6","Single Cell Type RNA - granulocytes [nTPM]":"7.0","Single Cell Type RNA - Granulosa cells [nTPM]":"27.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"9.7","Single Cell Type RNA - Hepatocytes [nTPM]":"4.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"7.7","Single Cell Type RNA - Horizontal cells [nTPM]":"5.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"5.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.5","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"8.9","Single Cell Type RNA - Langerhans cells [nTPM]":"12.3","Single Cell Type RNA - Late spermatids [nTPM]":"5.2","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"9.4","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"8.1","Single Cell Type RNA - Muller glia cells [nTPM]":"9.2","Single Cell Type RNA - NK-cells [nTPM]":"10.3","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"17.6","Single Cell Type RNA - Paneth cells [nTPM]":"13.3","Single Cell Type RNA - Peritubular cells [nTPM]":"10.1","Single Cell Type RNA - Plasma cells [nTPM]":"31.1","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"13.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"2.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"8.2","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.9","Single Cell Type RNA - Spermatocytes [nTPM]":"5.5","Single Cell Type RNA - Spermatogonia [nTPM]":"46.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"9.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"2.9","Single Cell Type RNA - T-cells [nTPM]":"12.5","Single Cell Type RNA - Theca cells [nTPM]":"10.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.1","Single Cell Type RNA - Urothelial cells [nTPM]":"8.5"},{"Gene":"TERT","Gene synonym":["EST2","hEST2","TCS1","TP2","TRT"],"Ensembl":"ENSG00000164362","Gene description":"Telomerase reverse transcriptase","Uniprot":["O14746"],"Chromosome":"5","Position":"1253147-1295068","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted membrane proteins"],"Biological process":null,"Molecular function":["DNA-binding","Nucleotidyltransferase","Ribonucleoprotein","RNA-directed DNA polymerase","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant","Dyskeratosis congenita"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Not detected","RNA tissue distribution":"Not detected","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Cardiomyocytes":"1.4","Intestinal goblet cells":"1.0","Plasma cells":"2.8","Spermatocytes":"1.5","Spermatogonia":"4.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC TERT1":"438.0","fHDF\/TERT166":"429.4","HBEC3-KT":"929.2","hTEC\/SVTERT24-B":"560.1","LHCN-M2":"252.2","TIME":"799.9"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA054641","HPA065897"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear speckles","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear speckles","Cytosol"],"Antibody RRID":{"HPA054641":"AB_2682554","HPA065897":"AB_2685576"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.21e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.88e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.24e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.43e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.42e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.85e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.91e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.16e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.84e-11"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.15e-1"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.35e-1"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.1","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.1","Tissue RNA - medulla oblongata [nTPM]":"0.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"0.1","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.5","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.1","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.1","Cell RNA - A549 [nTPM]":"0.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.5","Cell RNA - ASC diff [nTPM]":"213.2","Cell RNA - ASC TERT1 [nTPM]":"438.0","Cell RNA - BEWO [nTPM]":"3.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"173.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"31.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"59.4","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.1","Cell RNA - Daudi [nTPM]":"3.0","Cell RNA - EFO-21 [nTPM]":"0.2","Cell RNA - fHDF\/TERT166 [nTPM]":"429.4","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.1","Cell RNA - HAP1 [nTPM]":"1.0","Cell RNA - HBEC3-KT [nTPM]":"929.2","Cell RNA - HBF TERT88 [nTPM]":"29.1","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.7","Cell RNA - HEL [nTPM]":"0.1","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.4","Cell RNA - HHSteC [nTPM]":"0.1","Cell RNA - HL-60 [nTPM]":"0.5","Cell RNA - HMC-1 [nTPM]":"1.2","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"22.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"560.1","Cell RNA - hTERT-HME1 [nTPM]":"6.8","Cell RNA - hTERT-RPE1 [nTPM]":"1.3","Cell RNA - HUVEC TERT2 [nTPM]":"1.5","Cell RNA - JURKAT [nTPM]":"1.8","Cell RNA - K-562 [nTPM]":"2.9","Cell RNA - Karpas-707 [nTPM]":"0.2","Cell RNA - LHCN-M2 [nTPM]":"252.2","Cell RNA - MCF7 [nTPM]":"0.4","Cell RNA - MOLT-4 [nTPM]":"0.2","Cell RNA - NB-4 [nTPM]":"9.4","Cell RNA - NTERA-2 [nTPM]":"2.9","Cell RNA - OE19 [nTPM]":"0.1","Cell RNA - PC-3 [nTPM]":"1.3","Cell RNA - REH [nTPM]":"2.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"5.4","Cell RNA - RPTEC TERT1 [nTPM]":"23.9","Cell RNA - RT4 [nTPM]":"0.5","Cell RNA - SCLC-21H [nTPM]":"0.2","Cell RNA - SH-SY5Y [nTPM]":"2.1","Cell RNA - SiHa [nTPM]":"0.1","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.3","Cell RNA - TIME [nTPM]":"799.9","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.9","Cell RNA - U-266\/84 [nTPM]":"0.5","Cell RNA - U-698 [nTPM]":"0.7","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.2","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.4","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.3","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.1","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.0","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"1.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.2","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"2.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.0","Single Cell Type RNA - Spermatocytes [nTPM]":"1.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.1","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TET2","Gene synonym":["FLJ20032","KIAA1546"],"Ensembl":"ENSG00000168769","Gene description":"Tet methylcytosine dioxygenase 2","Uniprot":["Q6N021"],"Chromosome":"4","Position":"105145875-105279816","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":["Chromatin regulator","Dioxygenase","DNA-binding","Oxidoreductase"],"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"112.6","Oligodendrocytes":"128.3"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"55.5"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"55.5"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA043135"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 1: Neutrophils - Mixed function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA043135":"AB_10794177"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.83e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.69e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.42e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.88e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.12e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.15e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.77e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.29e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.70e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.10e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.89e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.84e-2"},"Tissue RNA - adipose tissue [nTPM]":"4.3","Tissue RNA - adrenal gland [nTPM]":"3.1","Tissue RNA - amygdala [nTPM]":"2.9","Tissue RNA - appendix [nTPM]":"10.1","Tissue RNA - basal ganglia [nTPM]":"4.4","Tissue RNA - bone marrow [nTPM]":"22.4","Tissue RNA - breast [nTPM]":"5.4","Tissue RNA - cerebellum [nTPM]":"2.5","Tissue RNA - cerebral cortex [nTPM]":"2.7","Tissue RNA - cervix [nTPM]":"6.3","Tissue RNA - choroid plexus [nTPM]":"5.8","Tissue RNA - colon [nTPM]":"5.2","Tissue RNA - duodenum [nTPM]":"6.1","Tissue RNA - endometrium 1 [nTPM]":"7.2","Tissue RNA - epididymis [nTPM]":"6.0","Tissue RNA - esophagus [nTPM]":"7.7","Tissue RNA - fallopian tube [nTPM]":"4.9","Tissue RNA - gallbladder [nTPM]":"5.0","Tissue RNA - heart muscle [nTPM]":"3.3","Tissue RNA - hippocampal formation [nTPM]":"2.1","Tissue RNA - hypothalamus [nTPM]":"4.6","Tissue RNA - kidney [nTPM]":"4.1","Tissue RNA - liver [nTPM]":"4.2","Tissue RNA - lung [nTPM]":"5.4","Tissue RNA - lymph node [nTPM]":"5.6","Tissue RNA - medulla oblongata [nTPM]":"5.3","Tissue RNA - midbrain [nTPM]":"4.4","Tissue RNA - ovary [nTPM]":"4.3","Tissue RNA - pancreas [nTPM]":"3.7","Tissue RNA - parathyroid gland [nTPM]":"4.6","Tissue RNA - pituitary gland [nTPM]":"1.8","Tissue RNA - placenta [nTPM]":"10.2","Tissue RNA - pons [nTPM]":"5.3","Tissue RNA - prostate [nTPM]":"4.4","Tissue RNA - rectum [nTPM]":"5.9","Tissue RNA - retina [nTPM]":"6.6","Tissue RNA - salivary gland [nTPM]":"4.7","Tissue RNA - seminal vesicle [nTPM]":"3.3","Tissue RNA - skeletal muscle [nTPM]":"2.8","Tissue RNA - skin 1 [nTPM]":"11.0","Tissue RNA - small intestine [nTPM]":"6.0","Tissue RNA - smooth muscle [nTPM]":"5.7","Tissue RNA - spinal cord [nTPM]":"2.9","Tissue RNA - spleen [nTPM]":"7.2","Tissue RNA - stomach 1 [nTPM]":"5.3","Tissue RNA - testis [nTPM]":"1.3","Tissue RNA - thalamus [nTPM]":"4.1","Tissue RNA - thymus [nTPM]":"5.4","Tissue RNA - thyroid gland [nTPM]":"4.2","Tissue RNA - tongue [nTPM]":"5.2","Tissue RNA - tonsil [nTPM]":"7.0","Tissue RNA - urinary bladder [nTPM]":"5.5","Tissue RNA - vagina [nTPM]":"4.5","Tissue RNA - white matter [nTPM]":"5.6","Cell RNA - A-431 [nTPM]":"5.1","Cell RNA - A549 [nTPM]":"3.1","Cell RNA - AF22 [nTPM]":"10.9","Cell RNA - AN3-CA [nTPM]":"11.1","Cell RNA - ASC diff [nTPM]":"2.1","Cell RNA - ASC TERT1 [nTPM]":"3.7","Cell RNA - BEWO [nTPM]":"4.2","Cell RNA - BJ [nTPM]":"3.1","Cell RNA - BJ hTERT+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"4.7","Cell RNA - CACO-2 [nTPM]":"3.1","Cell RNA - CAPAN-2 [nTPM]":"6.4","Cell RNA - Daudi [nTPM]":"0.5","Cell RNA - EFO-21 [nTPM]":"4.0","Cell RNA - fHDF\/TERT166 [nTPM]":"4.0","Cell RNA - GAMG [nTPM]":"2.1","Cell RNA - HaCaT [nTPM]":"4.9","Cell RNA - HAP1 [nTPM]":"9.3","Cell RNA - HBEC3-KT [nTPM]":"6.1","Cell RNA - HBF TERT88 [nTPM]":"5.3","Cell RNA - HDLM-2 [nTPM]":"6.7","Cell RNA - HEK 293 [nTPM]":"2.9","Cell RNA - HEL [nTPM]":"7.0","Cell RNA - HeLa [nTPM]":"6.5","Cell RNA - Hep G2 [nTPM]":"1.6","Cell RNA - HHSteC [nTPM]":"4.9","Cell RNA - HL-60 [nTPM]":"15.5","Cell RNA - HMC-1 [nTPM]":"11.8","Cell RNA - HSkMC [nTPM]":"3.8","Cell RNA - hTCEpi [nTPM]":"7.9","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"4.5","Cell RNA - hTERT-HME1 [nTPM]":"5.6","Cell RNA - hTERT-RPE1 [nTPM]":"8.6","Cell RNA - HUVEC TERT2 [nTPM]":"6.4","Cell RNA - JURKAT [nTPM]":"4.1","Cell RNA - K-562 [nTPM]":"7.7","Cell RNA - Karpas-707 [nTPM]":"13.6","Cell RNA - LHCN-M2 [nTPM]":"4.4","Cell RNA - MCF7 [nTPM]":"3.1","Cell RNA - MOLT-4 [nTPM]":"2.5","Cell RNA - NB-4 [nTPM]":"4.7","Cell RNA - NTERA-2 [nTPM]":"2.5","Cell RNA - OE19 [nTPM]":"6.2","Cell RNA - PC-3 [nTPM]":"2.2","Cell RNA - REH [nTPM]":"8.4","Cell RNA - RH-30 [nTPM]":"4.7","Cell RNA - RPMI-8226 [nTPM]":"1.0","Cell RNA - RPTEC TERT1 [nTPM]":"4.7","Cell RNA - RT4 [nTPM]":"9.4","Cell RNA - SCLC-21H [nTPM]":"7.5","Cell RNA - SH-SY5Y [nTPM]":"5.9","Cell RNA - SiHa [nTPM]":"4.2","Cell RNA - SK-BR-3 [nTPM]":"9.1","Cell RNA - SK-MEL-30 [nTPM]":"0.8","Cell RNA - SuSa [nTPM]":"5.9","Cell RNA - T-47d [nTPM]":"4.5","Cell RNA - THP-1 [nTPM]":"11.8","Cell RNA - TIME [nTPM]":"9.1","Cell RNA - U-138 MG [nTPM]":"7.8","Cell RNA - U-2 OS [nTPM]":"6.7","Cell RNA - U-2197 [nTPM]":"2.1","Cell RNA - U-251 MG [nTPM]":"5.3","Cell RNA - U-266\/70 [nTPM]":"9.5","Cell RNA - U-266\/84 [nTPM]":"6.8","Cell RNA - U-698 [nTPM]":"6.8","Cell RNA - U-87 MG [nTPM]":"4.8","Cell RNA - U-937 [nTPM]":"3.8","Cell RNA - WM-115 [nTPM]":"7.2","Blood RNA - basophil [nTPM]":"30.1","Blood RNA - classical monocyte [nTPM]":"13.6","Blood RNA - eosinophil [nTPM]":"14.7","Blood RNA - gdT-cell [nTPM]":"3.9","Blood RNA - intermediate monocyte [nTPM]":"10.4","Blood RNA - MAIT T-cell [nTPM]":"1.6","Blood RNA - memory B-cell [nTPM]":"5.3","Blood RNA - memory CD4 T-cell [nTPM]":"2.3","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"10.2","Blood RNA - naive B-cell [nTPM]":"6.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.9","Blood RNA - naive CD8 T-cell [nTPM]":"2.9","Blood RNA - neutrophil [nTPM]":"55.5","Blood RNA - NK-cell [nTPM]":"5.9","Blood RNA - non-classical monocyte [nTPM]":"13.6","Blood RNA - plasmacytoid DC [nTPM]":"8.9","Blood RNA - T-reg [nTPM]":"3.1","Blood RNA - total PBMC [nTPM]":"3.3","Brain RNA - amygdala [nTPM]":"2.9","Brain RNA - basal ganglia [nTPM]":"4.4","Brain RNA - cerebellum [nTPM]":"2.5","Brain RNA - cerebral cortex [nTPM]":"2.7","Brain RNA - hippocampal formation [nTPM]":"2.1","Brain RNA - hypothalamus [nTPM]":"4.6","Brain RNA - medulla oblongata [nTPM]":"5.3","Brain RNA - midbrain [nTPM]":"4.4","Brain RNA - pons [nTPM]":"5.3","Brain RNA - spinal cord [nTPM]":"2.9","Brain RNA - thalamus [nTPM]":"4.1","Brain RNA - white matter [nTPM]":"5.6","Single Cell Type RNA - Adipocytes [nTPM]":"24.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"25.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"29.1","Single Cell Type RNA - Astrocytes [nTPM]":"58.8","Single Cell Type RNA - B-cells [nTPM]":"28.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"11.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.5","Single Cell Type RNA - Bipolar cells [nTPM]":"22.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"15.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"13.6","Single Cell Type RNA - Cardiomyocytes [nTPM]":"27.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"23.9","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"16.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - dendritic cells [nTPM]":"34.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"7.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"22.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"38.3","Single Cell Type RNA - Endothelial cells [nTPM]":"20.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"23.3","Single Cell Type RNA - Erythroid cells [nTPM]":"10.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"48.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"7.5","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.7","Single Cell Type RNA - Fibroblasts [nTPM]":"18.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"21.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"33.2","Single Cell Type RNA - granulocytes [nTPM]":"27.8","Single Cell Type RNA - Granulosa cells [nTPM]":"15.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"13.6","Single Cell Type RNA - Hepatocytes [nTPM]":"8.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.5","Single Cell Type RNA - Horizontal cells [nTPM]":"35.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"89.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"15.8","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"48.8","Single Cell Type RNA - Langerhans cells [nTPM]":"93.3","Single Cell Type RNA - Late spermatids [nTPM]":"0.9","Single Cell Type RNA - Leydig cells [nTPM]":"8.1","Single Cell Type RNA - Macrophages [nTPM]":"98.3","Single Cell Type RNA - Melanocytes [nTPM]":"5.4","Single Cell Type RNA - Microglial cells [nTPM]":"90.9","Single Cell Type RNA - monocytes [nTPM]":"48.1","Single Cell Type RNA - Muller glia cells [nTPM]":"5.8","Single Cell Type RNA - NK-cells [nTPM]":"34.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"112.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"128.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"8.2","Single Cell Type RNA - Paneth cells [nTPM]":"18.7","Single Cell Type RNA - Peritubular cells [nTPM]":"7.2","Single Cell Type RNA - Plasma cells [nTPM]":"22.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"12.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"16.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"22.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"24.3","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"47.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"21.7","Single Cell Type RNA - Spermatocytes [nTPM]":"0.2","Single Cell Type RNA - Spermatogonia [nTPM]":"1.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.4","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"35.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"34.2","Single Cell Type RNA - T-cells [nTPM]":"18.9","Single Cell Type RNA - Theca cells [nTPM]":"24.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.0","Single Cell Type RNA - Urothelial cells [nTPM]":"27.5"},{"Gene":"TFE3","Gene synonym":["bHLHe33","TFEA"],"Ensembl":"ENSG00000068323","Gene description":"Transcription factor binding to IGHM enhancer 3","Uniprot":["P19532"],"Chromosome":"X","Position":"49028726-49043410","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Adaptive immunity","Immunity","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"12.5"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"12.5","monocytes":"6.3"},"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA023881"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 57: Non-specific - Angiogenesis","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA023881":"AB_1857931"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.68e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.89e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.36e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.71e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.03e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.32e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.41e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.16e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"2.19e-8"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.93e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.77e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.25e-1"},"Tissue RNA - adipose tissue [nTPM]":"31.3","Tissue RNA - adrenal gland [nTPM]":"23.6","Tissue RNA - amygdala [nTPM]":"27.8","Tissue RNA - appendix [nTPM]":"16.8","Tissue RNA - basal ganglia [nTPM]":"27.3","Tissue RNA - bone marrow [nTPM]":"24.1","Tissue RNA - breast [nTPM]":"22.9","Tissue RNA - cerebellum [nTPM]":"25.8","Tissue RNA - cerebral cortex [nTPM]":"26.9","Tissue RNA - cervix [nTPM]":"24.1","Tissue RNA - choroid plexus [nTPM]":"23.3","Tissue RNA - colon [nTPM]":"23.6","Tissue RNA - duodenum [nTPM]":"10.8","Tissue RNA - endometrium 1 [nTPM]":"24.7","Tissue RNA - epididymis [nTPM]":"21.1","Tissue RNA - esophagus [nTPM]":"15.6","Tissue RNA - fallopian tube [nTPM]":"26.2","Tissue RNA - gallbladder [nTPM]":"18.5","Tissue RNA - heart muscle [nTPM]":"17.2","Tissue RNA - hippocampal formation [nTPM]":"25.7","Tissue RNA - hypothalamus [nTPM]":"29.4","Tissue RNA - kidney [nTPM]":"15.1","Tissue RNA - liver [nTPM]":"12.6","Tissue RNA - lung [nTPM]":"29.2","Tissue RNA - lymph node [nTPM]":"11.8","Tissue RNA - medulla oblongata [nTPM]":"37.2","Tissue RNA - midbrain [nTPM]":"30.9","Tissue RNA - ovary [nTPM]":"25.8","Tissue RNA - pancreas [nTPM]":"12.4","Tissue RNA - parathyroid gland [nTPM]":"25.1","Tissue RNA - pituitary gland [nTPM]":"18.4","Tissue RNA - placenta [nTPM]":"20.8","Tissue RNA - pons [nTPM]":"28.7","Tissue RNA - prostate [nTPM]":"17.2","Tissue RNA - rectum [nTPM]":"11.5","Tissue RNA - retina [nTPM]":"14.8","Tissue RNA - salivary gland [nTPM]":"13.4","Tissue RNA - seminal vesicle [nTPM]":"28.3","Tissue RNA - skeletal muscle [nTPM]":"17.0","Tissue RNA - skin 1 [nTPM]":"20.5","Tissue RNA - small intestine [nTPM]":"14.7","Tissue RNA - smooth muscle [nTPM]":"24.7","Tissue RNA - spinal cord [nTPM]":"27.5","Tissue RNA - spleen [nTPM]":"22.5","Tissue RNA - stomach 1 [nTPM]":"16.8","Tissue RNA - testis [nTPM]":"5.9","Tissue RNA - thalamus [nTPM]":"32.2","Tissue RNA - thymus [nTPM]":"10.7","Tissue RNA - thyroid gland [nTPM]":"20.0","Tissue RNA - tongue [nTPM]":"14.0","Tissue RNA - tonsil [nTPM]":"13.2","Tissue RNA - urinary bladder [nTPM]":"25.0","Tissue RNA - vagina [nTPM]":"20.5","Tissue RNA - white matter [nTPM]":"25.6","Cell RNA - A-431 [nTPM]":"32.8","Cell RNA - A549 [nTPM]":"41.5","Cell RNA - AF22 [nTPM]":"14.6","Cell RNA - AN3-CA [nTPM]":"44.6","Cell RNA - ASC diff [nTPM]":"48.6","Cell RNA - ASC TERT1 [nTPM]":"45.1","Cell RNA - BEWO [nTPM]":"12.5","Cell RNA - BJ [nTPM]":"40.6","Cell RNA - BJ hTERT+ [nTPM]":"55.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"38.2","Cell RNA - CACO-2 [nTPM]":"23.3","Cell RNA - CAPAN-2 [nTPM]":"26.8","Cell RNA - Daudi [nTPM]":"10.2","Cell RNA - EFO-21 [nTPM]":"18.0","Cell RNA - fHDF\/TERT166 [nTPM]":"65.7","Cell RNA - GAMG [nTPM]":"48.6","Cell RNA - HaCaT [nTPM]":"25.5","Cell RNA - HAP1 [nTPM]":"25.4","Cell RNA - HBEC3-KT [nTPM]":"40.2","Cell RNA - HBF TERT88 [nTPM]":"44.8","Cell RNA - HDLM-2 [nTPM]":"24.4","Cell RNA - HEK 293 [nTPM]":"11.8","Cell RNA - HEL [nTPM]":"8.3","Cell RNA - HeLa [nTPM]":"39.6","Cell RNA - Hep G2 [nTPM]":"26.2","Cell RNA - HHSteC [nTPM]":"69.0","Cell RNA - HL-60 [nTPM]":"10.0","Cell RNA - HMC-1 [nTPM]":"28.3","Cell RNA - HSkMC [nTPM]":"38.5","Cell RNA - hTCEpi [nTPM]":"32.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.4","Cell RNA - hTERT-HME1 [nTPM]":"50.1","Cell RNA - hTERT-RPE1 [nTPM]":"47.8","Cell RNA - HUVEC TERT2 [nTPM]":"26.3","Cell RNA - JURKAT [nTPM]":"8.4","Cell RNA - K-562 [nTPM]":"19.8","Cell RNA - Karpas-707 [nTPM]":"55.9","Cell RNA - LHCN-M2 [nTPM]":"49.2","Cell RNA - MCF7 [nTPM]":"20.6","Cell RNA - MOLT-4 [nTPM]":"7.5","Cell RNA - NB-4 [nTPM]":"17.2","Cell RNA - NTERA-2 [nTPM]":"36.3","Cell RNA - OE19 [nTPM]":"11.0","Cell RNA - PC-3 [nTPM]":"34.1","Cell RNA - REH [nTPM]":"11.9","Cell RNA - RH-30 [nTPM]":"22.2","Cell RNA - RPMI-8226 [nTPM]":"26.6","Cell RNA - RPTEC TERT1 [nTPM]":"43.1","Cell RNA - RT4 [nTPM]":"18.0","Cell RNA - SCLC-21H [nTPM]":"12.4","Cell RNA - SH-SY5Y [nTPM]":"12.4","Cell RNA - SiHa [nTPM]":"44.8","Cell RNA - SK-BR-3 [nTPM]":"19.0","Cell RNA - SK-MEL-30 [nTPM]":"17.9","Cell RNA - SuSa [nTPM]":"52.5","Cell RNA - T-47d [nTPM]":"27.6","Cell RNA - THP-1 [nTPM]":"15.0","Cell RNA - TIME [nTPM]":"48.5","Cell RNA - U-138 MG [nTPM]":"47.1","Cell RNA - U-2 OS [nTPM]":"48.7","Cell RNA - U-2197 [nTPM]":"48.0","Cell RNA - U-251 MG [nTPM]":"27.3","Cell RNA - U-266\/70 [nTPM]":"30.1","Cell RNA - U-266\/84 [nTPM]":"29.7","Cell RNA - U-698 [nTPM]":"8.0","Cell RNA - U-87 MG [nTPM]":"56.1","Cell RNA - U-937 [nTPM]":"14.0","Cell RNA - WM-115 [nTPM]":"33.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"4.8","Blood RNA - eosinophil [nTPM]":"1.8","Blood RNA - gdT-cell [nTPM]":"0.6","Blood RNA - intermediate monocyte [nTPM]":"4.7","Blood RNA - MAIT T-cell [nTPM]":"1.1","Blood RNA - memory B-cell [nTPM]":"0.5","Blood RNA - memory CD4 T-cell [nTPM]":"0.9","Blood RNA - memory CD8 T-cell [nTPM]":"0.5","Blood RNA - myeloid DC [nTPM]":"2.2","Blood RNA - naive B-cell [nTPM]":"1.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.6","Blood RNA - naive CD8 T-cell [nTPM]":"0.5","Blood RNA - neutrophil [nTPM]":"12.5","Blood RNA - NK-cell [nTPM]":"0.4","Blood RNA - non-classical monocyte [nTPM]":"6.3","Blood RNA - plasmacytoid DC [nTPM]":"0.5","Blood RNA - T-reg [nTPM]":"1.3","Blood RNA - total PBMC [nTPM]":"2.6","Brain RNA - amygdala [nTPM]":"27.8","Brain RNA - basal ganglia [nTPM]":"27.3","Brain RNA - cerebellum [nTPM]":"25.8","Brain RNA - cerebral cortex [nTPM]":"26.9","Brain RNA - hippocampal formation [nTPM]":"25.7","Brain RNA - hypothalamus [nTPM]":"29.4","Brain RNA - medulla oblongata [nTPM]":"37.2","Brain RNA - midbrain [nTPM]":"30.9","Brain RNA - pons [nTPM]":"28.7","Brain RNA - spinal cord [nTPM]":"27.5","Brain RNA - thalamus [nTPM]":"32.2","Brain RNA - white matter [nTPM]":"25.6","Single Cell Type RNA - Adipocytes [nTPM]":"13.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"16.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.8","Single Cell Type RNA - Astrocytes [nTPM]":"13.7","Single Cell Type RNA - B-cells [nTPM]":"9.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"19.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"19.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"11.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"30.1","Single Cell Type RNA - Bipolar cells [nTPM]":"6.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"9.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"15.7","Single Cell Type RNA - Club cells [nTPM]":"11.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"4.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.0","Single Cell Type RNA - dendritic cells [nTPM]":"4.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.3","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"17.7","Single Cell Type RNA - Early spermatids [nTPM]":"0.7","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"10.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.3","Single Cell Type RNA - Endothelial cells [nTPM]":"17.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"12.5","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"7.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"9.4","Single Cell Type RNA - Fibroblasts [nTPM]":"20.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.8","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"12.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"10.8","Single Cell Type RNA - Hepatocytes [nTPM]":"15.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.3","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"7.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"8.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"21.7","Single Cell Type RNA - Langerhans cells [nTPM]":"29.4","Single Cell Type RNA - Late spermatids [nTPM]":"2.2","Single Cell Type RNA - Leydig cells [nTPM]":"27.4","Single Cell Type RNA - Macrophages [nTPM]":"20.5","Single Cell Type RNA - Melanocytes [nTPM]":"8.8","Single Cell Type RNA - Microglial cells [nTPM]":"11.2","Single Cell Type RNA - monocytes [nTPM]":"15.5","Single Cell Type RNA - Muller glia cells [nTPM]":"12.0","Single Cell Type RNA - NK-cells [nTPM]":"4.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"7.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"21.4","Single Cell Type RNA - Paneth cells [nTPM]":"13.7","Single Cell Type RNA - Peritubular cells [nTPM]":"24.5","Single Cell Type RNA - Plasma cells [nTPM]":"12.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"20.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"12.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"7.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"5.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"14.3","Single Cell Type RNA - Spermatocytes [nTPM]":"2.2","Single Cell Type RNA - Spermatogonia [nTPM]":"0.8","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"18.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"22.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"37.1","Single Cell Type RNA - T-cells [nTPM]":"8.6","Single Cell Type RNA - Theca cells [nTPM]":"13.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"7.5","Single Cell Type RNA - Urothelial cells [nTPM]":"19.6"},{"Gene":"TFG","Gene synonym":["FLJ36137","SPG57","TF6"],"Ensembl":"ENSG00000114354","Gene description":"Trafficking from ER to golgi regulator","Uniprot":["Q92734"],"Chromosome":"3","Position":"100709295-100748964","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["ER-Golgi transport","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary spastic paraplegia","Neurodegeneration","Neuropathy","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019473","HPA052206"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"320000","Blood expression cluster":"Cluster 38: Basophils - Unknown function","Tissue expression cluster":"Cluster 87: Intestine & Kidney - Transmembrane transport","Cell line expression cluster":"Cluster 30: Epithelial cell lines - Translation","Single cell expression cluster":"Cluster 55: Plasma cells - Humoral immune response","Subcellular main location":["Vesicles"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA019473":"AB_1857936","HPA052206":"AB_2681760"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.58e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.14e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.48e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.42e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.73e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.50e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.58e-3"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.72e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.82e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.55e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.33e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.45e-2"},"Tissue RNA - adipose tissue [nTPM]":"62.2","Tissue RNA - adrenal gland [nTPM]":"73.0","Tissue RNA - amygdala [nTPM]":"40.7","Tissue RNA - appendix [nTPM]":"37.2","Tissue RNA - basal ganglia [nTPM]":"40.4","Tissue RNA - bone marrow [nTPM]":"37.4","Tissue RNA - breast [nTPM]":"52.4","Tissue RNA - cerebellum [nTPM]":"43.5","Tissue RNA - cerebral cortex [nTPM]":"46.4","Tissue RNA - cervix [nTPM]":"53.9","Tissue RNA - choroid plexus [nTPM]":"46.7","Tissue RNA - colon [nTPM]":"63.8","Tissue RNA - duodenum [nTPM]":"89.8","Tissue RNA - endometrium 1 [nTPM]":"52.0","Tissue RNA - epididymis [nTPM]":"78.5","Tissue RNA - esophagus [nTPM]":"85.7","Tissue RNA - fallopian tube [nTPM]":"51.2","Tissue RNA - gallbladder [nTPM]":"56.4","Tissue RNA - heart muscle [nTPM]":"82.6","Tissue RNA - hippocampal formation [nTPM]":"41.3","Tissue RNA - hypothalamus [nTPM]":"45.4","Tissue RNA - kidney [nTPM]":"71.9","Tissue RNA - liver [nTPM]":"113.9","Tissue RNA - lung [nTPM]":"55.6","Tissue RNA - lymph node [nTPM]":"29.4","Tissue RNA - medulla oblongata [nTPM]":"44.2","Tissue RNA - midbrain [nTPM]":"43.2","Tissue RNA - ovary [nTPM]":"48.2","Tissue RNA - pancreas [nTPM]":"66.7","Tissue RNA - parathyroid gland [nTPM]":"89.0","Tissue RNA - pituitary gland [nTPM]":"64.1","Tissue RNA - placenta [nTPM]":"79.2","Tissue RNA - pons [nTPM]":"44.4","Tissue RNA - prostate [nTPM]":"47.9","Tissue RNA - rectum [nTPM]":"69.6","Tissue RNA - retina [nTPM]":"40.9","Tissue RNA - salivary gland [nTPM]":"60.6","Tissue RNA - seminal vesicle [nTPM]":"61.3","Tissue RNA - skeletal muscle [nTPM]":"75.5","Tissue RNA - skin 1 [nTPM]":"58.9","Tissue RNA - small intestine [nTPM]":"76.6","Tissue RNA - smooth muscle [nTPM]":"66.5","Tissue RNA - spinal cord [nTPM]":"43.2","Tissue RNA - spleen [nTPM]":"42.6","Tissue RNA - stomach 1 [nTPM]":"54.4","Tissue RNA - testis [nTPM]":"47.7","Tissue RNA - thalamus [nTPM]":"42.3","Tissue RNA - thymus [nTPM]":"40.6","Tissue RNA - thyroid gland [nTPM]":"64.1","Tissue RNA - tongue [nTPM]":"58.2","Tissue RNA - tonsil [nTPM]":"54.9","Tissue RNA - urinary bladder [nTPM]":"61.6","Tissue RNA - vagina [nTPM]":"57.3","Tissue RNA - white matter [nTPM]":"44.4","Cell RNA - A-431 [nTPM]":"203.8","Cell RNA - A549 [nTPM]":"107.5","Cell RNA - AF22 [nTPM]":"126.7","Cell RNA - AN3-CA [nTPM]":"79.0","Cell RNA - ASC diff [nTPM]":"160.1","Cell RNA - ASC TERT1 [nTPM]":"176.4","Cell RNA - BEWO [nTPM]":"163.9","Cell RNA - BJ [nTPM]":"141.1","Cell RNA - BJ hTERT+ [nTPM]":"190.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"182.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"213.0","Cell RNA - CACO-2 [nTPM]":"136.0","Cell RNA - CAPAN-2 [nTPM]":"96.1","Cell RNA - Daudi [nTPM]":"24.7","Cell RNA - EFO-21 [nTPM]":"103.3","Cell RNA - fHDF\/TERT166 [nTPM]":"180.4","Cell RNA - GAMG [nTPM]":"141.3","Cell RNA - HaCaT [nTPM]":"143.1","Cell RNA - HAP1 [nTPM]":"143.4","Cell RNA - HBEC3-KT [nTPM]":"161.5","Cell RNA - HBF TERT88 [nTPM]":"216.2","Cell RNA - HDLM-2 [nTPM]":"123.8","Cell RNA - HEK 293 [nTPM]":"87.4","Cell RNA - HEL [nTPM]":"99.7","Cell RNA - HeLa [nTPM]":"69.3","Cell RNA - Hep G2 [nTPM]":"130.0","Cell RNA - HHSteC [nTPM]":"183.3","Cell RNA - HL-60 [nTPM]":"70.2","Cell RNA - HMC-1 [nTPM]":"51.8","Cell RNA - HSkMC [nTPM]":"149.3","Cell RNA - hTCEpi [nTPM]":"216.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"108.4","Cell RNA - hTERT-HME1 [nTPM]":"190.8","Cell RNA - hTERT-RPE1 [nTPM]":"165.1","Cell RNA - HUVEC TERT2 [nTPM]":"165.5","Cell RNA - JURKAT [nTPM]":"44.5","Cell RNA - K-562 [nTPM]":"73.1","Cell RNA - Karpas-707 [nTPM]":"63.5","Cell RNA - LHCN-M2 [nTPM]":"191.9","Cell RNA - MCF7 [nTPM]":"143.9","Cell RNA - MOLT-4 [nTPM]":"63.3","Cell RNA - NB-4 [nTPM]":"56.7","Cell RNA - NTERA-2 [nTPM]":"122.5","Cell RNA - OE19 [nTPM]":"193.8","Cell RNA - PC-3 [nTPM]":"169.3","Cell RNA - REH [nTPM]":"55.5","Cell RNA - RH-30 [nTPM]":"77.8","Cell RNA - RPMI-8226 [nTPM]":"89.0","Cell RNA - RPTEC TERT1 [nTPM]":"226.5","Cell RNA - RT4 [nTPM]":"125.9","Cell RNA - SCLC-21H [nTPM]":"96.4","Cell RNA - SH-SY5Y [nTPM]":"93.1","Cell RNA - SiHa [nTPM]":"95.0","Cell RNA - SK-BR-3 [nTPM]":"118.2","Cell RNA - SK-MEL-30 [nTPM]":"175.8","Cell RNA - SuSa [nTPM]":"103.4","Cell RNA - T-47d [nTPM]":"141.7","Cell RNA - THP-1 [nTPM]":"103.1","Cell RNA - TIME [nTPM]":"113.1","Cell RNA - U-138 MG [nTPM]":"103.0","Cell RNA - U-2 OS [nTPM]":"130.8","Cell RNA - U-2197 [nTPM]":"48.4","Cell RNA - U-251 MG [nTPM]":"104.4","Cell RNA - U-266\/70 [nTPM]":"56.2","Cell RNA - U-266\/84 [nTPM]":"65.8","Cell RNA - U-698 [nTPM]":"92.1","Cell RNA - U-87 MG [nTPM]":"171.2","Cell RNA - U-937 [nTPM]":"79.7","Cell RNA - WM-115 [nTPM]":"130.7","Blood RNA - basophil [nTPM]":"84.3","Blood RNA - classical monocyte [nTPM]":"43.6","Blood RNA - eosinophil [nTPM]":"42.8","Blood RNA - gdT-cell [nTPM]":"30.8","Blood RNA - intermediate monocyte [nTPM]":"45.2","Blood RNA - MAIT T-cell [nTPM]":"37.4","Blood RNA - memory B-cell [nTPM]":"37.4","Blood RNA - memory CD4 T-cell [nTPM]":"31.6","Blood RNA - memory CD8 T-cell [nTPM]":"34.5","Blood RNA - myeloid DC [nTPM]":"43.1","Blood RNA - naive B-cell [nTPM]":"35.9","Blood RNA - naive CD4 T-cell [nTPM]":"29.4","Blood RNA - naive CD8 T-cell [nTPM]":"29.7","Blood RNA - neutrophil [nTPM]":"26.1","Blood RNA - NK-cell [nTPM]":"43.1","Blood RNA - non-classical monocyte [nTPM]":"44.8","Blood RNA - plasmacytoid DC [nTPM]":"29.3","Blood RNA - T-reg [nTPM]":"41.0","Blood RNA - total PBMC [nTPM]":"37.0","Brain RNA - amygdala [nTPM]":"40.7","Brain RNA - basal ganglia [nTPM]":"40.4","Brain RNA - cerebellum [nTPM]":"43.5","Brain RNA - cerebral cortex [nTPM]":"46.4","Brain RNA - hippocampal formation [nTPM]":"41.3","Brain RNA - hypothalamus [nTPM]":"45.4","Brain RNA - medulla oblongata [nTPM]":"44.2","Brain RNA - midbrain [nTPM]":"43.2","Brain RNA - pons [nTPM]":"44.4","Brain RNA - spinal cord [nTPM]":"43.2","Brain RNA - thalamus [nTPM]":"42.3","Brain RNA - white matter [nTPM]":"44.4","Single Cell Type RNA - Adipocytes [nTPM]":"67.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"60.9","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"36.9","Single Cell Type RNA - Astrocytes [nTPM]":"46.4","Single Cell Type RNA - B-cells [nTPM]":"43.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"136.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"183.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"69.4","Single Cell Type RNA - Bipolar cells [nTPM]":"46.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"58.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"50.2","Single Cell Type RNA - Cardiomyocytes [nTPM]":"83.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"48.6","Single Cell Type RNA - Club cells [nTPM]":"93.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"36.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"25.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"211.6","Single Cell Type RNA - dendritic cells [nTPM]":"43.1","Single Cell Type RNA - Distal enterocytes [nTPM]":"111.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"137.0","Single Cell Type RNA - Ductal cells [nTPM]":"190.3","Single Cell Type RNA - Early spermatids [nTPM]":"101.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"70.8","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.4","Single Cell Type RNA - Endothelial cells [nTPM]":"70.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"52.6","Single Cell Type RNA - Erythroid cells [nTPM]":"27.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"54.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"107.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"201.5","Single Cell Type RNA - Fibroblasts [nTPM]":"97.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"47.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"79.0","Single Cell Type RNA - granulocytes [nTPM]":"76.8","Single Cell Type RNA - Granulosa cells [nTPM]":"62.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"53.9","Single Cell Type RNA - Hepatocytes [nTPM]":"68.4","Single Cell Type RNA - Hofbauer cells [nTPM]":"86.2","Single Cell Type RNA - Horizontal cells [nTPM]":"57.2","Single Cell Type RNA - Inhibitory neurons [nTPM]":"59.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"128.5","Single Cell Type RNA - Ionocytes [nTPM]":"122.1","Single Cell Type RNA - Kupffer cells [nTPM]":"27.3","Single Cell Type RNA - Langerhans cells [nTPM]":"84.9","Single Cell Type RNA - Late spermatids [nTPM]":"45.5","Single Cell Type RNA - Leydig cells [nTPM]":"70.8","Single Cell Type RNA - Macrophages [nTPM]":"43.6","Single Cell Type RNA - Melanocytes [nTPM]":"64.0","Single Cell Type RNA - Microglial cells [nTPM]":"38.4","Single Cell Type RNA - monocytes [nTPM]":"98.5","Single Cell Type RNA - Muller glia cells [nTPM]":"88.0","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"49.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"55.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"130.5","Single Cell Type RNA - Paneth cells [nTPM]":"91.0","Single Cell Type RNA - Peritubular cells [nTPM]":"74.1","Single Cell Type RNA - Plasma cells [nTPM]":"75.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"133.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"202.5","Single Cell Type RNA - Proximal tubular cells [nTPM]":"106.4","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"63.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.3","Single Cell Type RNA - Sertoli cells [nTPM]":"39.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"81.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"87.2","Single Cell Type RNA - Spermatocytes [nTPM]":"79.2","Single Cell Type RNA - Spermatogonia [nTPM]":"51.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"68.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"118.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"284.4","Single Cell Type RNA - T-cells [nTPM]":"43.2","Single Cell Type RNA - Theca cells [nTPM]":"90.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"97.2","Single Cell Type RNA - Urothelial cells [nTPM]":"123.0"},{"Gene":"TGFA","Gene synonym":[],"Ensembl":"ENSG00000163235","Gene description":"Transforming growth factor alpha","Uniprot":["P01135"],"Chromosome":"2","Position":"70447284-70554193","Protein class":["Cancer-related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins","RAS pathway related proteins"],"Biological process":null,"Molecular function":["Growth factor","Mitogen"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"27.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Oligodendrocyte precursor cells":"59.3","Pancreatic endocrine cells":"74.5","Urothelial cells":"63.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"11.3","eosinophil":"23.8","neutrophil":"23.8"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"23.8"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"A-431":"72.5","CAPAN-2":"82.5","HBEC3-KT":"72.3","OE19":"54.6","RPTEC TERT1":"72.6","U-87 MG":"69.0"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA042297"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":57900,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 27: Brain & Skin - Unknown function","Cell line expression cluster":"Cluster 42: Epithelial cell lines - Epithelial cell function","Single cell expression cluster":"Cluster 22: Epithelial cell types - Mixed function","Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA042297":"AB_10793878"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.57e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.39e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.41e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.49e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.00e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.69e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.20e-5"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.74e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.21e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.52e-4"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.19e-2"},"Tissue RNA - adipose tissue [nTPM]":"2.2","Tissue RNA - adrenal gland [nTPM]":"0.5","Tissue RNA - amygdala [nTPM]":"9.2","Tissue RNA - appendix [nTPM]":"5.0","Tissue RNA - basal ganglia [nTPM]":"16.8","Tissue RNA - bone marrow [nTPM]":"1.6","Tissue RNA - breast [nTPM]":"6.9","Tissue RNA - cerebellum [nTPM]":"15.0","Tissue RNA - cerebral cortex [nTPM]":"12.2","Tissue RNA - cervix [nTPM]":"6.1","Tissue RNA - choroid plexus [nTPM]":"5.2","Tissue RNA - colon [nTPM]":"10.7","Tissue RNA - duodenum [nTPM]":"8.5","Tissue RNA - endometrium 1 [nTPM]":"1.3","Tissue RNA - epididymis [nTPM]":"2.9","Tissue RNA - esophagus [nTPM]":"25.5","Tissue RNA - fallopian tube [nTPM]":"6.1","Tissue RNA - gallbladder [nTPM]":"14.1","Tissue RNA - heart muscle [nTPM]":"0.7","Tissue RNA - hippocampal formation [nTPM]":"10.4","Tissue RNA - hypothalamus [nTPM]":"11.7","Tissue RNA - kidney [nTPM]":"13.4","Tissue RNA - liver [nTPM]":"4.5","Tissue RNA - lung [nTPM]":"3.9","Tissue RNA - lymph node [nTPM]":"4.1","Tissue RNA - medulla oblongata [nTPM]":"21.0","Tissue RNA - midbrain [nTPM]":"15.8","Tissue RNA - ovary [nTPM]":"0.1","Tissue RNA - pancreas [nTPM]":"7.5","Tissue RNA - parathyroid gland [nTPM]":"3.0","Tissue RNA - pituitary gland [nTPM]":"0.5","Tissue RNA - placenta [nTPM]":"1.9","Tissue RNA - pons [nTPM]":"18.5","Tissue RNA - prostate [nTPM]":"2.4","Tissue RNA - rectum [nTPM]":"7.9","Tissue RNA - retina [nTPM]":"7.4","Tissue RNA - salivary gland [nTPM]":"6.4","Tissue RNA - seminal vesicle [nTPM]":"1.2","Tissue RNA - skeletal muscle [nTPM]":"0.1","Tissue RNA - skin 1 [nTPM]":"12.2","Tissue RNA - small intestine [nTPM]":"10.0","Tissue RNA - smooth muscle [nTPM]":"1.4","Tissue RNA - spinal cord [nTPM]":"16.6","Tissue RNA - spleen [nTPM]":"5.8","Tissue RNA - stomach 1 [nTPM]":"8.5","Tissue RNA - testis [nTPM]":"2.5","Tissue RNA - thalamus [nTPM]":"13.2","Tissue RNA - thymus [nTPM]":"1.0","Tissue RNA - thyroid gland [nTPM]":"8.1","Tissue RNA - tongue [nTPM]":"0.3","Tissue RNA - tonsil [nTPM]":"9.0","Tissue RNA - urinary bladder [nTPM]":"10.0","Tissue RNA - vagina [nTPM]":"12.8","Tissue RNA - white matter [nTPM]":"27.3","Cell RNA - A-431 [nTPM]":"72.5","Cell RNA - A549 [nTPM]":"11.3","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.2","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"11.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.3","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.1","Cell RNA - CACO-2 [nTPM]":"0.2","Cell RNA - CAPAN-2 [nTPM]":"82.5","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"43.2","Cell RNA - fHDF\/TERT166 [nTPM]":"0.4","Cell RNA - GAMG [nTPM]":"11.2","Cell RNA - HaCaT [nTPM]":"37.1","Cell RNA - HAP1 [nTPM]":"0.6","Cell RNA - HBEC3-KT [nTPM]":"72.3","Cell RNA - HBF TERT88 [nTPM]":"0.1","Cell RNA - HDLM-2 [nTPM]":"0.1","Cell RNA - HEK 293 [nTPM]":"1.6","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"1.8","Cell RNA - Hep G2 [nTPM]":"6.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.1","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"29.1","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.1","Cell RNA - hTERT-HME1 [nTPM]":"27.8","Cell RNA - hTERT-RPE1 [nTPM]":"3.4","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"5.6","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.4","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"2.6","Cell RNA - MOLT-4 [nTPM]":"0.1","Cell RNA - NB-4 [nTPM]":"1.4","Cell RNA - NTERA-2 [nTPM]":"1.1","Cell RNA - OE19 [nTPM]":"54.6","Cell RNA - PC-3 [nTPM]":"22.9","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.5","Cell RNA - RPMI-8226 [nTPM]":"19.8","Cell RNA - RPTEC TERT1 [nTPM]":"72.6","Cell RNA - RT4 [nTPM]":"27.2","Cell RNA - SCLC-21H [nTPM]":"0.6","Cell RNA - SH-SY5Y [nTPM]":"0.1","Cell RNA - SiHa [nTPM]":"5.8","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"9.8","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"0.6","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"4.9","Cell RNA - U-2197 [nTPM]":"0.1","Cell RNA - U-251 MG [nTPM]":"15.7","Cell RNA - U-266\/70 [nTPM]":"0.4","Cell RNA - U-266\/84 [nTPM]":"0.6","Cell RNA - U-698 [nTPM]":"0.1","Cell RNA - U-87 MG [nTPM]":"69.0","Cell RNA - U-937 [nTPM]":"2.4","Cell RNA - WM-115 [nTPM]":"25.6","Blood RNA - basophil [nTPM]":"11.3","Blood RNA - classical monocyte [nTPM]":"0.8","Blood RNA - eosinophil [nTPM]":"23.8","Blood RNA - gdT-cell [nTPM]":"1.7","Blood RNA - intermediate monocyte [nTPM]":"0.2","Blood RNA - MAIT T-cell [nTPM]":"4.4","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"1.0","Blood RNA - memory CD8 T-cell [nTPM]":"1.0","Blood RNA - myeloid DC [nTPM]":"1.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.5","Blood RNA - naive CD8 T-cell [nTPM]":"0.4","Blood RNA - neutrophil [nTPM]":"23.8","Blood RNA - NK-cell [nTPM]":"0.3","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.7","Brain RNA - amygdala [nTPM]":"9.2","Brain RNA - basal ganglia [nTPM]":"16.8","Brain RNA - cerebellum [nTPM]":"15.0","Brain RNA - cerebral cortex [nTPM]":"12.2","Brain RNA - hippocampal formation [nTPM]":"10.4","Brain RNA - hypothalamus [nTPM]":"11.7","Brain RNA - medulla oblongata [nTPM]":"21.0","Brain RNA - midbrain [nTPM]":"15.8","Brain RNA - pons [nTPM]":"18.5","Brain RNA - spinal cord [nTPM]":"16.6","Brain RNA - thalamus [nTPM]":"13.2","Brain RNA - white matter [nTPM]":"27.3","Single Cell Type RNA - Adipocytes [nTPM]":"0.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"2.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"12.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"10.8","Single Cell Type RNA - Bipolar cells [nTPM]":"1.4","Single Cell Type RNA - Breast glandular cells [nTPM]":"9.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"24.3","Single Cell Type RNA - Club cells [nTPM]":"21.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"25.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"2.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.8","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"37.3","Single Cell Type RNA - Early spermatids [nTPM]":"21.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"8.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.7","Single Cell Type RNA - Endothelial cells [nTPM]":"1.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"1.2","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"10.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.6","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"13.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"10.5","Single Cell Type RNA - granulocytes [nTPM]":"5.7","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"3.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"3.9","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"6.2","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"3.2","Single Cell Type RNA - Langerhans cells [nTPM]":"2.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.9","Single Cell Type RNA - Leydig cells [nTPM]":"0.3","Single Cell Type RNA - Macrophages [nTPM]":"4.1","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"6.5","Single Cell Type RNA - monocytes [nTPM]":"18.2","Single Cell Type RNA - Muller glia cells [nTPM]":"7.9","Single Cell Type RNA - NK-cells [nTPM]":"2.1","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"59.3","Single Cell Type RNA - Oligodendrocytes [nTPM]":"36.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"74.5","Single Cell Type RNA - Paneth cells [nTPM]":"9.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"16.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"21.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"20.4","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"1.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.6","Single Cell Type RNA - Spermatogonia [nTPM]":"0.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.2","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"24.9","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"1.9","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"5.6","Single Cell Type RNA - Urothelial cells [nTPM]":"63.6"},{"Gene":"TGFBR1","Gene synonym":["ACVRLK4","ALK-5","ALK5","ESS1","MSSE","TBR-i","TBRI"],"Ensembl":"ENSG00000106799","Gene description":"Transforming growth factor beta receptor 1","Uniprot":["P36897"],"Chromosome":"9","Position":"99104038-99154192","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation","Growth regulation"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Craniosynostosis","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Early spermatids":"128.4","Late spermatids":"101.7","Microglial cells":"116.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"253.1"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002441","CAB031481","HPA056473"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":"Intracellular and membrane","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 40: Neutrophils - Inflammatory response","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 65: Plasmacytoid DCs - Unknown function","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB002441":"AB_564029","CAB031481":"AB_2202455","HPA056473":"AB_2683144"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.20e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.64e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.63e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.36e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.32e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.97e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.21e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.01e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.19e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.14e-2"},"Tissue RNA - adipose tissue [nTPM]":"15.9","Tissue RNA - adrenal gland [nTPM]":"9.9","Tissue RNA - amygdala [nTPM]":"9.8","Tissue RNA - appendix [nTPM]":"18.2","Tissue RNA - basal ganglia [nTPM]":"9.3","Tissue RNA - bone marrow [nTPM]":"33.7","Tissue RNA - breast [nTPM]":"15.4","Tissue RNA - cerebellum [nTPM]":"13.2","Tissue RNA - cerebral cortex [nTPM]":"8.9","Tissue RNA - cervix [nTPM]":"19.4","Tissue RNA - choroid plexus [nTPM]":"11.8","Tissue RNA - colon [nTPM]":"18.8","Tissue RNA - duodenum [nTPM]":"11.7","Tissue RNA - endometrium 1 [nTPM]":"20.6","Tissue RNA - epididymis [nTPM]":"8.8","Tissue RNA - esophagus [nTPM]":"15.0","Tissue RNA - fallopian tube [nTPM]":"8.5","Tissue RNA - gallbladder [nTPM]":"21.7","Tissue RNA - heart muscle [nTPM]":"8.2","Tissue RNA - hippocampal formation [nTPM]":"6.8","Tissue RNA - hypothalamus [nTPM]":"11.3","Tissue RNA - kidney [nTPM]":"22.6","Tissue RNA - liver [nTPM]":"14.8","Tissue RNA - lung [nTPM]":"16.3","Tissue RNA - lymph node [nTPM]":"13.8","Tissue RNA - medulla oblongata [nTPM]":"18.4","Tissue RNA - midbrain [nTPM]":"14.5","Tissue RNA - ovary [nTPM]":"13.0","Tissue RNA - pancreas [nTPM]":"8.3","Tissue RNA - parathyroid gland [nTPM]":"8.5","Tissue RNA - pituitary gland [nTPM]":"7.6","Tissue RNA - placenta [nTPM]":"48.8","Tissue RNA - pons [nTPM]":"20.0","Tissue RNA - prostate [nTPM]":"17.1","Tissue RNA - rectum [nTPM]":"13.4","Tissue RNA - retina [nTPM]":"4.7","Tissue RNA - salivary gland [nTPM]":"8.3","Tissue RNA - seminal vesicle [nTPM]":"16.8","Tissue RNA - skeletal muscle [nTPM]":"8.7","Tissue RNA - skin 1 [nTPM]":"6.2","Tissue RNA - small intestine [nTPM]":"9.3","Tissue RNA - smooth muscle [nTPM]":"33.0","Tissue RNA - spinal cord [nTPM]":"18.0","Tissue RNA - spleen [nTPM]":"16.5","Tissue RNA - stomach 1 [nTPM]":"18.4","Tissue RNA - testis [nTPM]":"18.3","Tissue RNA - thalamus [nTPM]":"17.5","Tissue RNA - thymus [nTPM]":"11.2","Tissue RNA - thyroid gland [nTPM]":"11.2","Tissue RNA - tongue [nTPM]":"13.2","Tissue RNA - tonsil [nTPM]":"13.6","Tissue RNA - urinary bladder [nTPM]":"22.5","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"27.9","Cell RNA - A-431 [nTPM]":"13.7","Cell RNA - A549 [nTPM]":"19.5","Cell RNA - AF22 [nTPM]":"115.5","Cell RNA - AN3-CA [nTPM]":"36.1","Cell RNA - ASC diff [nTPM]":"26.2","Cell RNA - ASC TERT1 [nTPM]":"19.3","Cell RNA - BEWO [nTPM]":"17.4","Cell RNA - BJ [nTPM]":"44.1","Cell RNA - BJ hTERT+ [nTPM]":"47.8","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"40.7","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.9","Cell RNA - CACO-2 [nTPM]":"19.9","Cell RNA - CAPAN-2 [nTPM]":"9.3","Cell RNA - Daudi [nTPM]":"29.7","Cell RNA - EFO-21 [nTPM]":"13.4","Cell RNA - fHDF\/TERT166 [nTPM]":"34.6","Cell RNA - GAMG [nTPM]":"32.1","Cell RNA - HaCaT [nTPM]":"30.4","Cell RNA - HAP1 [nTPM]":"39.6","Cell RNA - HBEC3-KT [nTPM]":"34.1","Cell RNA - HBF TERT88 [nTPM]":"54.0","Cell RNA - HDLM-2 [nTPM]":"77.1","Cell RNA - HEK 293 [nTPM]":"12.3","Cell RNA - HEL [nTPM]":"43.9","Cell RNA - HeLa [nTPM]":"20.7","Cell RNA - Hep G2 [nTPM]":"17.8","Cell RNA - HHSteC [nTPM]":"43.2","Cell RNA - HL-60 [nTPM]":"27.2","Cell RNA - HMC-1 [nTPM]":"102.8","Cell RNA - HSkMC [nTPM]":"40.2","Cell RNA - hTCEpi [nTPM]":"35.4","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"62.8","Cell RNA - hTERT-HME1 [nTPM]":"29.5","Cell RNA - hTERT-RPE1 [nTPM]":"25.2","Cell RNA - HUVEC TERT2 [nTPM]":"7.4","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"62.4","Cell RNA - Karpas-707 [nTPM]":"12.1","Cell RNA - LHCN-M2 [nTPM]":"55.4","Cell RNA - MCF7 [nTPM]":"20.3","Cell RNA - MOLT-4 [nTPM]":"4.0","Cell RNA - NB-4 [nTPM]":"31.0","Cell RNA - NTERA-2 [nTPM]":"24.7","Cell RNA - OE19 [nTPM]":"12.2","Cell RNA - PC-3 [nTPM]":"11.5","Cell RNA - REH [nTPM]":"11.0","Cell RNA - RH-30 [nTPM]":"253.1","Cell RNA - RPMI-8226 [nTPM]":"12.5","Cell RNA - RPTEC TERT1 [nTPM]":"9.9","Cell RNA - RT4 [nTPM]":"3.8","Cell RNA - SCLC-21H [nTPM]":"31.1","Cell RNA - SH-SY5Y [nTPM]":"36.2","Cell RNA - SiHa [nTPM]":"34.3","Cell RNA - SK-BR-3 [nTPM]":"150.2","Cell RNA - SK-MEL-30 [nTPM]":"46.4","Cell RNA - SuSa [nTPM]":"47.3","Cell RNA - T-47d [nTPM]":"28.1","Cell RNA - THP-1 [nTPM]":"36.6","Cell RNA - TIME [nTPM]":"13.6","Cell RNA - U-138 MG [nTPM]":"29.8","Cell RNA - U-2 OS [nTPM]":"25.5","Cell RNA - U-2197 [nTPM]":"129.3","Cell RNA - U-251 MG [nTPM]":"27.3","Cell RNA - U-266\/70 [nTPM]":"12.1","Cell RNA - U-266\/84 [nTPM]":"13.4","Cell RNA - U-698 [nTPM]":"20.0","Cell RNA - U-87 MG [nTPM]":"62.5","Cell RNA - U-937 [nTPM]":"45.9","Cell RNA - WM-115 [nTPM]":"26.2","Blood RNA - basophil [nTPM]":"16.2","Blood RNA - classical monocyte [nTPM]":"2.4","Blood RNA - eosinophil [nTPM]":"9.5","Blood RNA - gdT-cell [nTPM]":"7.8","Blood RNA - intermediate monocyte [nTPM]":"1.6","Blood RNA - MAIT T-cell [nTPM]":"6.7","Blood RNA - memory B-cell [nTPM]":"1.6","Blood RNA - memory CD4 T-cell [nTPM]":"3.3","Blood RNA - memory CD8 T-cell [nTPM]":"5.8","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"1.2","Blood RNA - naive CD4 T-cell [nTPM]":"3.2","Blood RNA - naive CD8 T-cell [nTPM]":"6.2","Blood RNA - neutrophil [nTPM]":"4.9","Blood RNA - NK-cell [nTPM]":"4.3","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"1.4","Blood RNA - T-reg [nTPM]":"2.4","Blood RNA - total PBMC [nTPM]":"2.2","Brain RNA - amygdala [nTPM]":"9.8","Brain RNA - basal ganglia [nTPM]":"9.3","Brain RNA - cerebellum [nTPM]":"13.2","Brain RNA - cerebral cortex [nTPM]":"8.9","Brain RNA - hippocampal formation [nTPM]":"6.8","Brain RNA - hypothalamus [nTPM]":"11.3","Brain RNA - medulla oblongata [nTPM]":"18.4","Brain RNA - midbrain [nTPM]":"14.5","Brain RNA - pons [nTPM]":"20.0","Brain RNA - spinal cord [nTPM]":"18.0","Brain RNA - thalamus [nTPM]":"17.5","Brain RNA - white matter [nTPM]":"27.9","Single Cell Type RNA - Adipocytes [nTPM]":"13.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"6.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"8.8","Single Cell Type RNA - Astrocytes [nTPM]":"18.9","Single Cell Type RNA - B-cells [nTPM]":"18.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"23.6","Single Cell Type RNA - Basal prostatic cells [nTPM]":"7.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"19.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"44.3","Single Cell Type RNA - Bipolar cells [nTPM]":"8.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"18.9","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"11.7","Single Cell Type RNA - Cardiomyocytes [nTPM]":"7.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"4.3","Single Cell Type RNA - Club cells [nTPM]":"12.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"60.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.0","Single Cell Type RNA - dendritic cells [nTPM]":"37.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"5.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"18.8","Single Cell Type RNA - Early spermatids [nTPM]":"128.4","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"6.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"22.7","Single Cell Type RNA - Endothelial cells [nTPM]":"17.6","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"9.6","Single Cell Type RNA - Erythroid cells [nTPM]":"7.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"14.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"31.2","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"6.7","Single Cell Type RNA - Fibroblasts [nTPM]":"36.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"9.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"9.3","Single Cell Type RNA - granulocytes [nTPM]":"29.9","Single Cell Type RNA - Granulosa cells [nTPM]":"19.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"6.4","Single Cell Type RNA - Hepatocytes [nTPM]":"12.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"49.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"7.3","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"32.4","Single Cell Type RNA - Langerhans cells [nTPM]":"52.5","Single Cell Type RNA - Late spermatids [nTPM]":"101.7","Single Cell Type RNA - Leydig cells [nTPM]":"9.6","Single Cell Type RNA - Macrophages [nTPM]":"39.7","Single Cell Type RNA - Melanocytes [nTPM]":"35.6","Single Cell Type RNA - Microglial cells [nTPM]":"116.2","Single Cell Type RNA - monocytes [nTPM]":"24.3","Single Cell Type RNA - Muller glia cells [nTPM]":"3.1","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"21.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"33.8","Single Cell Type RNA - Paneth cells [nTPM]":"4.2","Single Cell Type RNA - Peritubular cells [nTPM]":"13.5","Single Cell Type RNA - Plasma cells [nTPM]":"11.9","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"18.4","Single Cell Type RNA - Proximal enterocytes [nTPM]":"3.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"5.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.0","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"21.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.9","Single Cell Type RNA - Spermatocytes [nTPM]":"11.0","Single Cell Type RNA - Spermatogonia [nTPM]":"12.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"25.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"16.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"19.4","Single Cell Type RNA - T-cells [nTPM]":"25.4","Single Cell Type RNA - Theca cells [nTPM]":"7.6","Single Cell Type RNA - Undifferentiated cells [nTPM]":"8.3","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"TGFBR2","Gene synonym":["MFS2","TBR-ii","TBRII"],"Ensembl":"ENSG00000163513","Gene description":"Transforming growth factor beta receptor 2","Uniprot":["P37173"],"Chromosome":"3","Position":"30606601-30694142","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Differentiation","Growth regulation"],"Molecular function":["Kinase","Receptor","Serine\/threonine-protein kinase","Transferase"],"Disease involvement":["Aortic aneurysm","Cancer-related genes","Craniosynostosis","Disease variant","FDA approved drug targets","Hereditary nonpolyposis colorectal cancer"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Adipocytes":"391.5","Endothelial cells":"236.4","Hepatic stellate cells":"478.0"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"313.6","ASC TERT1":"472.3","HSkMC":"430.0","LHCN-M2":"381.7","TIME":"418.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB073537"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"810000","Blood expression cluster":"Cluster 5: Granulocytes - Unknown function","Tissue expression cluster":"Cluster 82: Adipose tissue - ECM organization","Cell line expression cluster":"Cluster 41: TIME & HUVEC\/TERT2 - Endothelial cell function","Single cell expression cluster":"Cluster 14: Adipocytes & Endothelial cells - Angiogenesis","Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"CAB073537":null},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.74e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.84e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.70e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.02e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.92e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.26e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.96e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.24e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.36e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.12e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.72e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.81e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.02e-2"},"Tissue RNA - adipose tissue [nTPM]":"230.0","Tissue RNA - adrenal gland [nTPM]":"56.1","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"73.8","Tissue RNA - basal ganglia [nTPM]":"12.9","Tissue RNA - bone marrow [nTPM]":"29.4","Tissue RNA - breast [nTPM]":"145.7","Tissue RNA - cerebellum [nTPM]":"13.8","Tissue RNA - cerebral cortex [nTPM]":"19.3","Tissue RNA - cervix [nTPM]":"90.0","Tissue RNA - choroid plexus [nTPM]":"30.6","Tissue RNA - colon [nTPM]":"96.0","Tissue RNA - duodenum [nTPM]":"44.2","Tissue RNA - endometrium 1 [nTPM]":"69.1","Tissue RNA - epididymis [nTPM]":"18.2","Tissue RNA - esophagus [nTPM]":"44.9","Tissue RNA - fallopian tube [nTPM]":"69.6","Tissue RNA - gallbladder [nTPM]":"91.9","Tissue RNA - heart muscle [nTPM]":"95.2","Tissue RNA - hippocampal formation [nTPM]":"10.6","Tissue RNA - hypothalamus [nTPM]":"13.4","Tissue RNA - kidney [nTPM]":"67.9","Tissue RNA - liver [nTPM]":"59.1","Tissue RNA - lung [nTPM]":"148.0","Tissue RNA - lymph node [nTPM]":"70.1","Tissue RNA - medulla oblongata [nTPM]":"17.6","Tissue RNA - midbrain [nTPM]":"16.5","Tissue RNA - ovary [nTPM]":"26.6","Tissue RNA - pancreas [nTPM]":"52.0","Tissue RNA - parathyroid gland [nTPM]":"59.0","Tissue RNA - pituitary gland [nTPM]":"16.9","Tissue RNA - placenta [nTPM]":"81.6","Tissue RNA - pons [nTPM]":"16.7","Tissue RNA - prostate [nTPM]":"44.1","Tissue RNA - rectum [nTPM]":"54.1","Tissue RNA - retina [nTPM]":"2.1","Tissue RNA - salivary gland [nTPM]":"49.2","Tissue RNA - seminal vesicle [nTPM]":"60.8","Tissue RNA - skeletal muscle [nTPM]":"31.1","Tissue RNA - skin 1 [nTPM]":"39.1","Tissue RNA - small intestine [nTPM]":"77.7","Tissue RNA - smooth muscle [nTPM]":"107.2","Tissue RNA - spinal cord [nTPM]":"17.3","Tissue RNA - spleen [nTPM]":"111.1","Tissue RNA - stomach 1 [nTPM]":"63.4","Tissue RNA - testis [nTPM]":"7.8","Tissue RNA - thalamus [nTPM]":"21.5","Tissue RNA - thymus [nTPM]":"49.7","Tissue RNA - thyroid gland [nTPM]":"91.8","Tissue RNA - tongue [nTPM]":"62.2","Tissue RNA - tonsil [nTPM]":"60.7","Tissue RNA - urinary bladder [nTPM]":"98.0","Tissue RNA - vagina [nTPM]":"55.1","Tissue RNA - white matter [nTPM]":"17.2","Cell RNA - A-431 [nTPM]":"16.6","Cell RNA - A549 [nTPM]":"100.2","Cell RNA - AF22 [nTPM]":"5.3","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"313.6","Cell RNA - ASC TERT1 [nTPM]":"472.3","Cell RNA - BEWO [nTPM]":"15.9","Cell RNA - BJ [nTPM]":"83.9","Cell RNA - BJ hTERT+ [nTPM]":"116.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"28.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"27.7","Cell RNA - CACO-2 [nTPM]":"22.9","Cell RNA - CAPAN-2 [nTPM]":"86.6","Cell RNA - Daudi [nTPM]":"2.2","Cell RNA - EFO-21 [nTPM]":"298.2","Cell RNA - fHDF\/TERT166 [nTPM]":"117.2","Cell RNA - GAMG [nTPM]":"32.2","Cell RNA - HaCaT [nTPM]":"33.3","Cell RNA - HAP1 [nTPM]":"4.0","Cell RNA - HBEC3-KT [nTPM]":"125.4","Cell RNA - HBF TERT88 [nTPM]":"42.0","Cell RNA - HDLM-2 [nTPM]":"7.0","Cell RNA - HEK 293 [nTPM]":"8.9","Cell RNA - HEL [nTPM]":"10.1","Cell RNA - HeLa [nTPM]":"10.7","Cell RNA - Hep G2 [nTPM]":"104.5","Cell RNA - HHSteC [nTPM]":"128.5","Cell RNA - HL-60 [nTPM]":"14.9","Cell RNA - HMC-1 [nTPM]":"76.6","Cell RNA - HSkMC [nTPM]":"430.0","Cell RNA - hTCEpi [nTPM]":"93.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"126.3","Cell RNA - hTERT-HME1 [nTPM]":"114.4","Cell RNA - hTERT-RPE1 [nTPM]":"117.0","Cell RNA - HUVEC TERT2 [nTPM]":"296.0","Cell RNA - JURKAT [nTPM]":"10.9","Cell RNA - K-562 [nTPM]":"1.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"381.7","Cell RNA - MCF7 [nTPM]":"1.3","Cell RNA - MOLT-4 [nTPM]":"16.2","Cell RNA - NB-4 [nTPM]":"10.5","Cell RNA - NTERA-2 [nTPM]":"2.2","Cell RNA - OE19 [nTPM]":"75.7","Cell RNA - PC-3 [nTPM]":"39.8","Cell RNA - REH [nTPM]":"14.1","Cell RNA - RH-30 [nTPM]":"36.4","Cell RNA - RPMI-8226 [nTPM]":"2.1","Cell RNA - RPTEC TERT1 [nTPM]":"113.5","Cell RNA - RT4 [nTPM]":"40.5","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"5.6","Cell RNA - SiHa [nTPM]":"24.9","Cell RNA - SK-BR-3 [nTPM]":"6.1","Cell RNA - SK-MEL-30 [nTPM]":"22.0","Cell RNA - SuSa [nTPM]":"6.6","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"14.0","Cell RNA - TIME [nTPM]":"418.6","Cell RNA - U-138 MG [nTPM]":"134.7","Cell RNA - U-2 OS [nTPM]":"33.2","Cell RNA - U-2197 [nTPM]":"61.4","Cell RNA - U-251 MG [nTPM]":"32.0","Cell RNA - U-266\/70 [nTPM]":"2.8","Cell RNA - U-266\/84 [nTPM]":"0.3","Cell RNA - U-698 [nTPM]":"12.5","Cell RNA - U-87 MG [nTPM]":"80.1","Cell RNA - U-937 [nTPM]":"16.1","Cell RNA - WM-115 [nTPM]":"55.8","Blood RNA - basophil [nTPM]":"9.0","Blood RNA - classical monocyte [nTPM]":"3.0","Blood RNA - eosinophil [nTPM]":"11.5","Blood RNA - gdT-cell [nTPM]":"3.4","Blood RNA - intermediate monocyte [nTPM]":"3.1","Blood RNA - MAIT T-cell [nTPM]":"3.3","Blood RNA - memory B-cell [nTPM]":"4.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.8","Blood RNA - memory CD8 T-cell [nTPM]":"3.3","Blood RNA - myeloid DC [nTPM]":"2.6","Blood RNA - naive B-cell [nTPM]":"6.4","Blood RNA - naive CD4 T-cell [nTPM]":"16.6","Blood RNA - naive CD8 T-cell [nTPM]":"7.3","Blood RNA - neutrophil [nTPM]":"13.1","Blood RNA - NK-cell [nTPM]":"1.9","Blood RNA - non-classical monocyte [nTPM]":"8.0","Blood RNA - plasmacytoid DC [nTPM]":"6.6","Blood RNA - T-reg [nTPM]":"0.7","Blood RNA - total PBMC [nTPM]":"3.8","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"12.9","Brain RNA - cerebellum [nTPM]":"13.8","Brain RNA - cerebral cortex [nTPM]":"19.3","Brain RNA - hippocampal formation [nTPM]":"10.6","Brain RNA - hypothalamus [nTPM]":"13.4","Brain RNA - medulla oblongata [nTPM]":"17.6","Brain RNA - midbrain [nTPM]":"16.5","Brain RNA - pons [nTPM]":"16.7","Brain RNA - spinal cord [nTPM]":"17.3","Brain RNA - thalamus [nTPM]":"21.5","Brain RNA - white matter [nTPM]":"17.2","Single Cell Type RNA - Adipocytes [nTPM]":"391.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"144.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"99.7","Single Cell Type RNA - Astrocytes [nTPM]":"0.7","Single Cell Type RNA - B-cells [nTPM]":"77.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"37.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"18.9","Single Cell Type RNA - Basal respiratory cells [nTPM]":"23.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"39.9","Single Cell Type RNA - Bipolar cells [nTPM]":"5.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"23.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"24.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"84.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"50.1","Single Cell Type RNA - Club cells [nTPM]":"39.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"85.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"13.1","Single Cell Type RNA - Early spermatids [nTPM]":"2.5","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"28.3","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"57.5","Single Cell Type RNA - Endothelial cells [nTPM]":"236.4","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"8.4","Single Cell Type RNA - Erythroid cells [nTPM]":"20.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.4","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"15.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"5.1","Single Cell Type RNA - Fibroblasts [nTPM]":"129.2","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"39.3","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"30.8","Single Cell Type RNA - granulocytes [nTPM]":"29.8","Single Cell Type RNA - Granulosa cells [nTPM]":"0.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"478.0","Single Cell Type RNA - Hepatocytes [nTPM]":"55.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"30.4","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"1.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"12.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"147.0","Single Cell Type RNA - Langerhans cells [nTPM]":"58.0","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"32.9","Single Cell Type RNA - Macrophages [nTPM]":"67.9","Single Cell Type RNA - Melanocytes [nTPM]":"30.2","Single Cell Type RNA - Microglial cells [nTPM]":"170.5","Single Cell Type RNA - monocytes [nTPM]":"47.5","Single Cell Type RNA - Muller glia cells [nTPM]":"0.2","Single Cell Type RNA - NK-cells [nTPM]":"56.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"2.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.6","Single Cell Type RNA - Paneth cells [nTPM]":"12.1","Single Cell Type RNA - Peritubular cells [nTPM]":"47.4","Single Cell Type RNA - Plasma cells [nTPM]":"37.5","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"8.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"13.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"7.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"14.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.2","Single Cell Type RNA - Sertoli cells [nTPM]":"32.9","Single Cell Type RNA - Skeletal myocytes [nTPM]":"60.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"53.4","Single Cell Type RNA - Spermatocytes [nTPM]":"0.3","Single Cell Type RNA - Spermatogonia [nTPM]":"1.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"8.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"30.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"3.7","Single Cell Type RNA - T-cells [nTPM]":"68.2","Single Cell Type RNA - Theca cells [nTPM]":"1.7","Single Cell Type RNA - Undifferentiated cells [nTPM]":"14.5","Single Cell Type RNA - Urothelial cells [nTPM]":"10.8"},{"Gene":"TLX1","Gene synonym":["HOX11","TCL3"],"Ensembl":"ENSG00000107807","Gene description":"T cell leukemia homeobox 1","Uniprot":["P31314"],"Chromosome":"10","Position":"101131300-101137789","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"29","RNA tissue specific nTPM":{"lymphoid tissue":"43.9","salivary gland":"16.5"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Region enhanced","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":{"medulla oblongata":"1.0"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HAP1":"5.5","HEK 293":"2.5","K-562":"13.8","SCLC-21H":"2.2","SH-SY5Y":"3.3","SiHa":"2.7"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 43: Cardiomyocytes - Nuclear processes","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.67e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.23e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"7.32e-4"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.60e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.07e-1"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.57e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.12e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.52e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-1"},"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.63e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.26e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.06e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.35e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.2","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.0","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.1","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.3","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.9","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"1.0","Tissue RNA - midbrain [nTPM]":"0.0","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.3","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"0.1","Tissue RNA - pons [nTPM]":"0.7","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.1","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"16.5","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.8","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"43.9","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.3","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.2","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.1","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"1.6","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"1.8","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.1","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"5.5","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"2.5","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"13.8","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.1","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"2.2","Cell RNA - SH-SY5Y [nTPM]":"3.3","Cell RNA - SiHa [nTPM]":"2.7","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.2","Cell RNA - T-47d [nTPM]":"0.1","Cell RNA - THP-1 [nTPM]":"0.4","Cell RNA - TIME [nTPM]":"0.1","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"1.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.0","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"1.0","Brain RNA - midbrain [nTPM]":"0.0","Brain RNA - pons [nTPM]":"0.7","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"0.7","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.1","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.0","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.0","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.2","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.6","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.0","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.3","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TLX3","Gene synonym":["HOX11L2","RNX"],"Ensembl":"ENSG00000164438","Gene description":"T cell leukemia homeobox 3","Uniprot":["O43711"],"Chromosome":"5","Position":"171309248-171312139","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":null,"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in single","RNA tissue specificity score":"27","RNA tissue specific nTPM":{"brain":"9.0"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nTPM":{"Extravillous trophoblasts":"7.7"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"cervical cancer":"1.7"},"RNA brain regional specificity":"Group enriched","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":"6","RNA brain regional specific nTPM":{"cerebellum":"9.0","medulla oblongata":"2.3","spinal cord":"5.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"5","RNA cell line specific nTPM":{"SH-SY5Y":"25.9"},"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":"7","RNA mouse brain regional specific nTPM":{"cerebellum":"2.2"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":"8","RNA pig brain regional specific nTPM":{"cerebellum":"15.5"},"Antibody":["HPA030504","HPA060957","HPA069359"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 69: Cerebellum - Gene expression regulation","Cell line expression cluster":"Cluster 13: SH-SY5Y - Nervous system development","Single cell expression cluster":"Cluster 38: Extravillous trophoblasts - Unknown function","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA030504":"AB_2732458","HPA060957":"AB_2732655","HPA069359":"AB_2732130"},"Pathology prognostics - Breast cancer":null,"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Colorectal cancer":null,"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.43e-2"},"Pathology prognostics - Glioma":null,"Pathology prognostics - Head and neck cancer":null,"Pathology prognostics - Liver cancer":null,"Pathology prognostics - Lung cancer":null,"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.11e-1"},"Pathology prognostics - Pancreatic cancer":null,"Pathology prognostics - Prostate cancer":null,"Pathology prognostics - Renal cancer":null,"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.80e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Thyroid cancer":null,"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"0.0","Tissue RNA - adrenal gland [nTPM]":"0.0","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.0","Tissue RNA - basal ganglia [nTPM]":"0.0","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.0","Tissue RNA - cerebellum [nTPM]":"9.0","Tissue RNA - cerebral cortex [nTPM]":"0.4","Tissue RNA - cervix [nTPM]":"0.0","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.0","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"0.0","Tissue RNA - epididymis [nTPM]":"0.0","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"0.0","Tissue RNA - gallbladder [nTPM]":"0.0","Tissue RNA - heart muscle [nTPM]":"0.0","Tissue RNA - hippocampal formation [nTPM]":"0.0","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"0.0","Tissue RNA - liver [nTPM]":"0.0","Tissue RNA - lung [nTPM]":"0.0","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"2.3","Tissue RNA - midbrain [nTPM]":"0.6","Tissue RNA - ovary [nTPM]":"0.0","Tissue RNA - pancreas [nTPM]":"0.0","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.3","Tissue RNA - placenta [nTPM]":"0.0","Tissue RNA - pons [nTPM]":"1.0","Tissue RNA - prostate [nTPM]":"0.0","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"0.0","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.0","Tissue RNA - smooth muscle [nTPM]":"0.0","Tissue RNA - spinal cord [nTPM]":"5.3","Tissue RNA - spleen [nTPM]":"0.0","Tissue RNA - stomach 1 [nTPM]":"0.0","Tissue RNA - testis [nTPM]":"0.0","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.0","Tissue RNA - vagina [nTPM]":"0.0","Tissue RNA - white matter [nTPM]":"0.4","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"0.1","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.2","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.0","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"4.7","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.3","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"1.4","Cell RNA - HEL [nTPM]":"0.0","Cell RNA - HeLa [nTPM]":"4.3","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"0.0","Cell RNA - HL-60 [nTPM]":"0.0","Cell RNA - HMC-1 [nTPM]":"0.0","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.0","Cell RNA - K-562 [nTPM]":"0.0","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"0.0","Cell RNA - NB-4 [nTPM]":"0.0","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"3.1","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.2","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"25.9","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"1.4","Cell RNA - TIME [nTPM]":"0.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.0","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.0","Brain RNA - cerebellum [nTPM]":"9.0","Brain RNA - cerebral cortex [nTPM]":"0.4","Brain RNA - hippocampal formation [nTPM]":"0.0","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"2.3","Brain RNA - midbrain [nTPM]":"0.6","Brain RNA - pons [nTPM]":"1.0","Brain RNA - spinal cord [nTPM]":"5.3","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.4","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.0","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.0","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.2","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.2","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"0.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"0.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"0.0","Single Cell Type RNA - Endothelial cells [nTPM]":"0.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.0","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"7.7","Single Cell Type RNA - Fibroblasts [nTPM]":"0.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"0.2","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"0.0","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"0.0","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.1","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.0","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"0.0","Single Cell Type RNA - Leydig cells [nTPM]":"0.0","Single Cell Type RNA - Macrophages [nTPM]":"0.0","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"0.0","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"0.0","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"0.1","Single Cell Type RNA - Spermatocytes [nTPM]":"0.0","Single Cell Type RNA - Spermatogonia [nTPM]":"0.5","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"0.0","Single Cell Type RNA - Theca cells [nTPM]":"0.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.0"},{"Gene":"TMEM127","Gene synonym":["FLJ20507","FLJ22257"],"Ensembl":"ENSG00000135956","Gene description":"Transmembrane protein 127","Uniprot":["O75204"],"Chromosome":"2","Position":"96248514-96265997","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Distal enterocytes":"88.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 52: Eosinophils - Transcription","Tissue expression cluster":"Cluster 55: Non-specific - Mitochondria & Proteasome","Cell line expression cluster":"Cluster 8: SK-BR-3 - Unknown function","Single cell expression cluster":"Cluster 53: Intestinal epithelial cells - Unknown function","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.82e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.59e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.73e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.06e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.50e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"6.69e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.59e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.15e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.65e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.3","Tissue RNA - adrenal gland [nTPM]":"34.6","Tissue RNA - amygdala [nTPM]":"25.9","Tissue RNA - appendix [nTPM]":"28.5","Tissue RNA - basal ganglia [nTPM]":"24.6","Tissue RNA - bone marrow [nTPM]":"53.0","Tissue RNA - breast [nTPM]":"25.6","Tissue RNA - cerebellum [nTPM]":"20.1","Tissue RNA - cerebral cortex [nTPM]":"30.6","Tissue RNA - cervix [nTPM]":"30.7","Tissue RNA - choroid plexus [nTPM]":"15.7","Tissue RNA - colon [nTPM]":"34.4","Tissue RNA - duodenum [nTPM]":"32.6","Tissue RNA - endometrium 1 [nTPM]":"30.0","Tissue RNA - epididymis [nTPM]":"21.4","Tissue RNA - esophagus [nTPM]":"40.0","Tissue RNA - fallopian tube [nTPM]":"25.2","Tissue RNA - gallbladder [nTPM]":"32.3","Tissue RNA - heart muscle [nTPM]":"67.8","Tissue RNA - hippocampal formation [nTPM]":"26.7","Tissue RNA - hypothalamus [nTPM]":"23.6","Tissue RNA - kidney [nTPM]":"29.5","Tissue RNA - liver [nTPM]":"35.4","Tissue RNA - lung [nTPM]":"31.6","Tissue RNA - lymph node [nTPM]":"21.4","Tissue RNA - medulla oblongata [nTPM]":"24.5","Tissue RNA - midbrain [nTPM]":"26.3","Tissue RNA - ovary [nTPM]":"31.9","Tissue RNA - pancreas [nTPM]":"28.5","Tissue RNA - parathyroid gland [nTPM]":"73.1","Tissue RNA - pituitary gland [nTPM]":"29.4","Tissue RNA - placenta [nTPM]":"26.8","Tissue RNA - pons [nTPM]":"24.5","Tissue RNA - prostate [nTPM]":"26.1","Tissue RNA - rectum [nTPM]":"30.5","Tissue RNA - retina [nTPM]":"27.6","Tissue RNA - salivary gland [nTPM]":"39.7","Tissue RNA - seminal vesicle [nTPM]":"42.4","Tissue RNA - skeletal muscle [nTPM]":"25.9","Tissue RNA - skin 1 [nTPM]":"33.0","Tissue RNA - small intestine [nTPM]":"34.7","Tissue RNA - smooth muscle [nTPM]":"35.1","Tissue RNA - spinal cord [nTPM]":"21.1","Tissue RNA - spleen [nTPM]":"34.7","Tissue RNA - stomach 1 [nTPM]":"27.8","Tissue RNA - testis [nTPM]":"10.2","Tissue RNA - thalamus [nTPM]":"29.7","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"26.2","Tissue RNA - tongue [nTPM]":"30.6","Tissue RNA - tonsil [nTPM]":"25.4","Tissue RNA - urinary bladder [nTPM]":"38.6","Tissue RNA - vagina [nTPM]":"27.8","Tissue RNA - white matter [nTPM]":"21.9","Cell RNA - A-431 [nTPM]":"28.8","Cell RNA - A549 [nTPM]":"38.0","Cell RNA - AF22 [nTPM]":"19.9","Cell RNA - AN3-CA [nTPM]":"30.7","Cell RNA - ASC diff [nTPM]":"86.0","Cell RNA - ASC TERT1 [nTPM]":"43.3","Cell RNA - BEWO [nTPM]":"36.7","Cell RNA - BJ [nTPM]":"36.9","Cell RNA - BJ hTERT+ [nTPM]":"65.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"38.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"35.2","Cell RNA - CACO-2 [nTPM]":"37.9","Cell RNA - CAPAN-2 [nTPM]":"40.0","Cell RNA - Daudi [nTPM]":"17.9","Cell RNA - EFO-21 [nTPM]":"52.8","Cell RNA - fHDF\/TERT166 [nTPM]":"73.3","Cell RNA - GAMG [nTPM]":"67.8","Cell RNA - HaCaT [nTPM]":"45.1","Cell RNA - HAP1 [nTPM]":"23.1","Cell RNA - HBEC3-KT [nTPM]":"34.2","Cell RNA - HBF TERT88 [nTPM]":"26.8","Cell RNA - HDLM-2 [nTPM]":"36.1","Cell RNA - HEK 293 [nTPM]":"17.8","Cell RNA - HEL [nTPM]":"31.2","Cell RNA - HeLa [nTPM]":"17.6","Cell RNA - Hep G2 [nTPM]":"37.5","Cell RNA - HHSteC [nTPM]":"55.4","Cell RNA - HL-60 [nTPM]":"26.7","Cell RNA - HMC-1 [nTPM]":"54.0","Cell RNA - HSkMC [nTPM]":"52.7","Cell RNA - hTCEpi [nTPM]":"48.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.0","Cell RNA - hTERT-HME1 [nTPM]":"35.3","Cell RNA - hTERT-RPE1 [nTPM]":"51.4","Cell RNA - HUVEC TERT2 [nTPM]":"44.5","Cell RNA - JURKAT [nTPM]":"12.1","Cell RNA - K-562 [nTPM]":"19.5","Cell RNA - Karpas-707 [nTPM]":"37.6","Cell RNA - LHCN-M2 [nTPM]":"39.8","Cell RNA - MCF7 [nTPM]":"32.8","Cell RNA - MOLT-4 [nTPM]":"17.6","Cell RNA - NB-4 [nTPM]":"16.8","Cell RNA - NTERA-2 [nTPM]":"27.3","Cell RNA - OE19 [nTPM]":"33.9","Cell RNA - PC-3 [nTPM]":"40.4","Cell RNA - REH [nTPM]":"16.4","Cell RNA - RH-30 [nTPM]":"25.0","Cell RNA - RPMI-8226 [nTPM]":"26.9","Cell RNA - RPTEC TERT1 [nTPM]":"42.9","Cell RNA - RT4 [nTPM]":"48.7","Cell RNA - SCLC-21H [nTPM]":"22.3","Cell RNA - SH-SY5Y [nTPM]":"23.4","Cell RNA - SiHa [nTPM]":"27.1","Cell RNA - SK-BR-3 [nTPM]":"63.8","Cell RNA - SK-MEL-30 [nTPM]":"31.3","Cell RNA - SuSa [nTPM]":"40.2","Cell RNA - T-47d [nTPM]":"23.6","Cell RNA - THP-1 [nTPM]":"28.2","Cell RNA - TIME [nTPM]":"52.5","Cell RNA - U-138 MG [nTPM]":"63.9","Cell RNA - U-2 OS [nTPM]":"36.2","Cell RNA - U-2197 [nTPM]":"55.9","Cell RNA - U-251 MG [nTPM]":"25.8","Cell RNA - U-266\/70 [nTPM]":"28.2","Cell RNA - U-266\/84 [nTPM]":"29.6","Cell RNA - U-698 [nTPM]":"14.1","Cell RNA - U-87 MG [nTPM]":"42.6","Cell RNA - U-937 [nTPM]":"30.9","Cell RNA - WM-115 [nTPM]":"34.7","Blood RNA - basophil [nTPM]":"3.9","Blood RNA - classical monocyte [nTPM]":"6.3","Blood RNA - eosinophil [nTPM]":"8.2","Blood RNA - gdT-cell [nTPM]":"2.8","Blood RNA - intermediate monocyte [nTPM]":"6.6","Blood RNA - MAIT T-cell [nTPM]":"3.0","Blood RNA - memory B-cell [nTPM]":"1.8","Blood RNA - memory CD4 T-cell [nTPM]":"2.1","Blood RNA - memory CD8 T-cell [nTPM]":"3.0","Blood RNA - myeloid DC [nTPM]":"4.3","Blood RNA - naive B-cell [nTPM]":"1.9","Blood RNA - naive CD4 T-cell [nTPM]":"1.6","Blood RNA - naive CD8 T-cell [nTPM]":"2.2","Blood RNA - neutrophil [nTPM]":"14.3","Blood RNA - NK-cell [nTPM]":"1.5","Blood RNA - non-classical monocyte [nTPM]":"5.3","Blood RNA - plasmacytoid DC [nTPM]":"2.5","Blood RNA - T-reg [nTPM]":"1.6","Blood RNA - total PBMC [nTPM]":"3.2","Brain RNA - amygdala [nTPM]":"25.9","Brain RNA - basal ganglia [nTPM]":"24.6","Brain RNA - cerebellum [nTPM]":"20.1","Brain RNA - cerebral cortex [nTPM]":"30.6","Brain RNA - hippocampal formation [nTPM]":"26.7","Brain RNA - hypothalamus [nTPM]":"23.6","Brain RNA - medulla oblongata [nTPM]":"24.5","Brain RNA - midbrain [nTPM]":"26.3","Brain RNA - pons [nTPM]":"24.5","Brain RNA - spinal cord [nTPM]":"21.1","Brain RNA - thalamus [nTPM]":"29.7","Brain RNA - white matter [nTPM]":"21.9","Single Cell Type RNA - Adipocytes [nTPM]":"24.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"15.3","Single Cell Type RNA - Astrocytes [nTPM]":"7.2","Single Cell Type RNA - B-cells [nTPM]":"13.4","Single Cell Type RNA - Basal keratinocytes [nTPM]":"17.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"16.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"22.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"20.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"39.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"22.8","Single Cell Type RNA - Club cells [nTPM]":"20.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"27.6","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"27.1","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"11.4","Single Cell Type RNA - dendritic cells [nTPM]":"19.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"88.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"15.6","Single Cell Type RNA - Ductal cells [nTPM]":"29.7","Single Cell Type RNA - Early spermatids [nTPM]":"5.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"16.4","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"15.1","Single Cell Type RNA - Endothelial cells [nTPM]":"23.1","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.3","Single Cell Type RNA - Erythroid cells [nTPM]":"9.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"12.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"34.8","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"13.1","Single Cell Type RNA - Fibroblasts [nTPM]":"16.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"14.8","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"28.8","Single Cell Type RNA - granulocytes [nTPM]":"13.9","Single Cell Type RNA - Granulosa cells [nTPM]":"13.6","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"29.6","Single Cell Type RNA - Hepatocytes [nTPM]":"35.7","Single Cell Type RNA - Hofbauer cells [nTPM]":"37.7","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"15.7","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"26.7","Single Cell Type RNA - Ionocytes [nTPM]":"12.2","Single Cell Type RNA - Kupffer cells [nTPM]":"59.8","Single Cell Type RNA - Langerhans cells [nTPM]":"33.2","Single Cell Type RNA - Late spermatids [nTPM]":"5.8","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"34.0","Single Cell Type RNA - Melanocytes [nTPM]":"16.0","Single Cell Type RNA - Microglial cells [nTPM]":"5.6","Single Cell Type RNA - monocytes [nTPM]":"41.9","Single Cell Type RNA - Muller glia cells [nTPM]":"7.8","Single Cell Type RNA - NK-cells [nTPM]":"15.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"8.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"41.0","Single Cell Type RNA - Paneth cells [nTPM]":"35.1","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"13.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.9","Single Cell Type RNA - Proximal tubular cells [nTPM]":"13.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"15.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"16.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"18.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"19.4","Single Cell Type RNA - Spermatocytes [nTPM]":"9.1","Single Cell Type RNA - Spermatogonia [nTPM]":"2.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"12.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"23.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.2","Single Cell Type RNA - T-cells [nTPM]":"14.3","Single Cell Type RNA - Theca cells [nTPM]":"15.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"18.6","Single Cell Type RNA - Urothelial cells [nTPM]":"34.1"},{"Gene":"TNFAIP3","Gene synonym":["A20","OTUD7C"],"Ensembl":"ENSG00000118503","Gene description":"TNF alpha induced protein 3","Uniprot":["P21580"],"Chromosome":"6","Position":"137867214-137883312","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Inflammatory response","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Hydrolase","Multifunctional enzyme","Protease","Thiol protease","Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"519.5"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"774.9","Endometrial ciliated cells":"605.2","Glandular and luminal cells":"1498.3","Macrophages":"596.6","Suprabasal keratinocytes":"745.7","T-cells":"624.2"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"GAMG":"106.5","Karpas-707":"161.3","REH":"151.5","U-266\/84":"131.4"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA002116"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Centrosome","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 75: Bone marrow - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 2: Karpas-707 - Immune response","Single cell expression cluster":"Cluster 41: Macrophages - Immune response","Subcellular main location":["Centrosome","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA002116":"AB_1858162"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.50e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.98e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.06e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.01e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.01e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.47e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.01e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.40e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.58e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.06e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.05e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.06e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.55e-3"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.27e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.29e-2"},"Tissue RNA - adipose tissue [nTPM]":"57.0","Tissue RNA - adrenal gland [nTPM]":"15.6","Tissue RNA - amygdala [nTPM]":"4.4","Tissue RNA - appendix [nTPM]":"114.6","Tissue RNA - basal ganglia [nTPM]":"3.8","Tissue RNA - bone marrow [nTPM]":"519.5","Tissue RNA - breast [nTPM]":"23.3","Tissue RNA - cerebellum [nTPM]":"2.9","Tissue RNA - cerebral cortex [nTPM]":"23.9","Tissue RNA - cervix [nTPM]":"27.5","Tissue RNA - choroid plexus [nTPM]":"12.0","Tissue RNA - colon [nTPM]":"22.6","Tissue RNA - duodenum [nTPM]":"21.4","Tissue RNA - endometrium 1 [nTPM]":"31.3","Tissue RNA - epididymis [nTPM]":"5.2","Tissue RNA - esophagus [nTPM]":"26.6","Tissue RNA - fallopian tube [nTPM]":"23.4","Tissue RNA - gallbladder [nTPM]":"47.8","Tissue RNA - heart muscle [nTPM]":"23.0","Tissue RNA - hippocampal formation [nTPM]":"3.2","Tissue RNA - hypothalamus [nTPM]":"2.8","Tissue RNA - kidney [nTPM]":"13.8","Tissue RNA - liver [nTPM]":"27.4","Tissue RNA - lung [nTPM]":"56.2","Tissue RNA - lymph node [nTPM]":"76.8","Tissue RNA - medulla oblongata [nTPM]":"6.1","Tissue RNA - midbrain [nTPM]":"3.9","Tissue RNA - ovary [nTPM]":"73.2","Tissue RNA - pancreas [nTPM]":"25.8","Tissue RNA - parathyroid gland [nTPM]":"25.8","Tissue RNA - pituitary gland [nTPM]":"7.5","Tissue RNA - placenta [nTPM]":"28.9","Tissue RNA - pons [nTPM]":"6.7","Tissue RNA - prostate [nTPM]":"17.3","Tissue RNA - rectum [nTPM]":"24.7","Tissue RNA - retina [nTPM]":"19.1","Tissue RNA - salivary gland [nTPM]":"16.1","Tissue RNA - seminal vesicle [nTPM]":"10.3","Tissue RNA - skeletal muscle [nTPM]":"8.6","Tissue RNA - skin 1 [nTPM]":"50.5","Tissue RNA - small intestine [nTPM]":"30.7","Tissue RNA - smooth muscle [nTPM]":"33.5","Tissue RNA - spinal cord [nTPM]":"6.6","Tissue RNA - spleen [nTPM]":"46.1","Tissue RNA - stomach 1 [nTPM]":"22.8","Tissue RNA - testis [nTPM]":"8.3","Tissue RNA - thalamus [nTPM]":"9.5","Tissue RNA - thymus [nTPM]":"71.1","Tissue RNA - thyroid gland [nTPM]":"11.7","Tissue RNA - tongue [nTPM]":"3.8","Tissue RNA - tonsil [nTPM]":"55.7","Tissue RNA - urinary bladder [nTPM]":"171.1","Tissue RNA - vagina [nTPM]":"14.6","Tissue RNA - white matter [nTPM]":"6.2","Cell RNA - A-431 [nTPM]":"32.6","Cell RNA - A549 [nTPM]":"4.8","Cell RNA - AF22 [nTPM]":"1.8","Cell RNA - AN3-CA [nTPM]":"2.8","Cell RNA - ASC diff [nTPM]":"10.1","Cell RNA - ASC TERT1 [nTPM]":"16.9","Cell RNA - BEWO [nTPM]":"7.8","Cell RNA - BJ [nTPM]":"18.8","Cell RNA - BJ hTERT+ [nTPM]":"67.6","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.7","Cell RNA - CACO-2 [nTPM]":"34.9","Cell RNA - CAPAN-2 [nTPM]":"8.8","Cell RNA - Daudi [nTPM]":"7.3","Cell RNA - EFO-21 [nTPM]":"43.1","Cell RNA - fHDF\/TERT166 [nTPM]":"20.0","Cell RNA - GAMG [nTPM]":"106.5","Cell RNA - HaCaT [nTPM]":"22.6","Cell RNA - HAP1 [nTPM]":"1.1","Cell RNA - HBEC3-KT [nTPM]":"50.4","Cell RNA - HBF TERT88 [nTPM]":"8.9","Cell RNA - HDLM-2 [nTPM]":"46.8","Cell RNA - HEK 293 [nTPM]":"2.2","Cell RNA - HEL [nTPM]":"7.5","Cell RNA - HeLa [nTPM]":"19.8","Cell RNA - Hep G2 [nTPM]":"21.1","Cell RNA - HHSteC [nTPM]":"11.2","Cell RNA - HL-60 [nTPM]":"10.3","Cell RNA - HMC-1 [nTPM]":"12.8","Cell RNA - HSkMC [nTPM]":"15.6","Cell RNA - hTCEpi [nTPM]":"7.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"56.4","Cell RNA - hTERT-HME1 [nTPM]":"53.6","Cell RNA - hTERT-RPE1 [nTPM]":"5.6","Cell RNA - HUVEC TERT2 [nTPM]":"2.9","Cell RNA - JURKAT [nTPM]":"21.2","Cell RNA - K-562 [nTPM]":"17.4","Cell RNA - Karpas-707 [nTPM]":"161.3","Cell RNA - LHCN-M2 [nTPM]":"8.4","Cell RNA - MCF7 [nTPM]":"1.8","Cell RNA - MOLT-4 [nTPM]":"56.2","Cell RNA - NB-4 [nTPM]":"41.4","Cell RNA - NTERA-2 [nTPM]":"1.5","Cell RNA - OE19 [nTPM]":"2.1","Cell RNA - PC-3 [nTPM]":"1.4","Cell RNA - REH [nTPM]":"151.5","Cell RNA - RH-30 [nTPM]":"39.4","Cell RNA - RPMI-8226 [nTPM]":"6.1","Cell RNA - RPTEC TERT1 [nTPM]":"14.8","Cell RNA - RT4 [nTPM]":"15.1","Cell RNA - SCLC-21H [nTPM]":"0.7","Cell RNA - SH-SY5Y [nTPM]":"0.3","Cell RNA - SiHa [nTPM]":"3.6","Cell RNA - SK-BR-3 [nTPM]":"5.3","Cell RNA - SK-MEL-30 [nTPM]":"16.9","Cell RNA - SuSa [nTPM]":"7.0","Cell RNA - T-47d [nTPM]":"3.4","Cell RNA - THP-1 [nTPM]":"11.7","Cell RNA - TIME [nTPM]":"14.8","Cell RNA - U-138 MG [nTPM]":"46.9","Cell RNA - U-2 OS [nTPM]":"6.8","Cell RNA - U-2197 [nTPM]":"46.0","Cell RNA - U-251 MG [nTPM]":"9.6","Cell RNA - U-266\/70 [nTPM]":"48.7","Cell RNA - U-266\/84 [nTPM]":"131.4","Cell RNA - U-698 [nTPM]":"14.0","Cell RNA - U-87 MG [nTPM]":"16.9","Cell RNA - U-937 [nTPM]":"13.1","Cell RNA - WM-115 [nTPM]":"6.1","Blood RNA - basophil [nTPM]":"7.3","Blood RNA - classical monocyte [nTPM]":"12.6","Blood RNA - eosinophil [nTPM]":"9.6","Blood RNA - gdT-cell [nTPM]":"19.6","Blood RNA - intermediate monocyte [nTPM]":"9.3","Blood RNA - MAIT T-cell [nTPM]":"27.9","Blood RNA - memory B-cell [nTPM]":"7.4","Blood RNA - memory CD4 T-cell [nTPM]":"19.4","Blood RNA - memory CD8 T-cell [nTPM]":"18.0","Blood RNA - myeloid DC [nTPM]":"14.3","Blood RNA - naive B-cell [nTPM]":"7.8","Blood RNA - naive CD4 T-cell [nTPM]":"13.1","Blood RNA - naive CD8 T-cell [nTPM]":"10.1","Blood RNA - neutrophil [nTPM]":"13.6","Blood RNA - NK-cell [nTPM]":"11.1","Blood RNA - non-classical monocyte [nTPM]":"5.1","Blood RNA - plasmacytoid DC [nTPM]":"26.2","Blood RNA - T-reg [nTPM]":"19.2","Blood RNA - total PBMC [nTPM]":"14.8","Brain RNA - amygdala [nTPM]":"4.4","Brain RNA - basal ganglia [nTPM]":"3.8","Brain RNA - cerebellum [nTPM]":"2.9","Brain RNA - cerebral cortex [nTPM]":"23.9","Brain RNA - hippocampal formation [nTPM]":"3.2","Brain RNA - hypothalamus [nTPM]":"2.8","Brain RNA - medulla oblongata [nTPM]":"6.1","Brain RNA - midbrain [nTPM]":"3.9","Brain RNA - pons [nTPM]":"6.7","Brain RNA - spinal cord [nTPM]":"6.6","Brain RNA - thalamus [nTPM]":"9.5","Brain RNA - white matter [nTPM]":"6.2","Single Cell Type RNA - Adipocytes [nTPM]":"71.8","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"38.5","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"76.3","Single Cell Type RNA - Astrocytes [nTPM]":"2.0","Single Cell Type RNA - B-cells [nTPM]":"94.5","Single Cell Type RNA - Basal keratinocytes [nTPM]":"774.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"150.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"102.1","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"384.7","Single Cell Type RNA - Bipolar cells [nTPM]":"1.1","Single Cell Type RNA - Breast glandular cells [nTPM]":"29.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"42.3","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"25.8","Single Cell Type RNA - Club cells [nTPM]":"53.7","Single Cell Type RNA - Collecting duct cells [nTPM]":"0.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"29.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"8.1","Single Cell Type RNA - dendritic cells [nTPM]":"395.5","Single Cell Type RNA - Distal enterocytes [nTPM]":"53.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"60.0","Single Cell Type RNA - Early spermatids [nTPM]":"2.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"605.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"365.9","Single Cell Type RNA - Endothelial cells [nTPM]":"114.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"11.9","Single Cell Type RNA - Erythroid cells [nTPM]":"5.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"26.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"104.8","Single Cell Type RNA - Fibroblasts [nTPM]":"110.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"111.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1498.3","Single Cell Type RNA - granulocytes [nTPM]":"255.9","Single Cell Type RNA - Granulosa cells [nTPM]":"2.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"48.5","Single Cell Type RNA - Hepatocytes [nTPM]":"13.5","Single Cell Type RNA - Hofbauer cells [nTPM]":"45.7","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.3","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.6","Single Cell Type RNA - Ionocytes [nTPM]":"67.1","Single Cell Type RNA - Kupffer cells [nTPM]":"125.2","Single Cell Type RNA - Langerhans cells [nTPM]":"461.8","Single Cell Type RNA - Late spermatids [nTPM]":"3.2","Single Cell Type RNA - Leydig cells [nTPM]":"6.8","Single Cell Type RNA - Macrophages [nTPM]":"596.6","Single Cell Type RNA - Melanocytes [nTPM]":"129.9","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"59.1","Single Cell Type RNA - Muller glia cells [nTPM]":"1.7","Single Cell Type RNA - NK-cells [nTPM]":"14.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"30.5","Single Cell Type RNA - Paneth cells [nTPM]":"29.5","Single Cell Type RNA - Peritubular cells [nTPM]":"6.0","Single Cell Type RNA - Plasma cells [nTPM]":"331.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"170.2","Single Cell Type RNA - Proximal enterocytes [nTPM]":"37.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"84.3","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"13.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"29.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"94.9","Single Cell Type RNA - Spermatocytes [nTPM]":"2.7","Single Cell Type RNA - Spermatogonia [nTPM]":"2.2","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"367.9","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"745.7","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.1","Single Cell Type RNA - T-cells [nTPM]":"624.2","Single Cell Type RNA - Theca cells [nTPM]":"14.9","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.9","Single Cell Type RNA - Urothelial cells [nTPM]":"78.1"},{"Gene":"TNFRSF14","Gene synonym":["ATAR","CD270","HVEA","HVEM","LIGHTR","TR2"],"Ensembl":"ENSG00000157873","Gene description":"TNF receptor superfamily member 14","Uniprot":["Q92956"],"Chromosome":"1","Position":"2555639-2565382","Protein class":["Cancer-related genes","CD markers","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":["Host cell receptor for virus entry","Receptor"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Proximal enterocytes":"219.6"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"SK-MEL-30":"16.2"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA006404","CAB026150","CAB030007"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"110000","Blood expression cluster":"Cluster 8: Neutrophils - Inflammatory response","Tissue expression cluster":"Cluster 64: Macrophages - Immune response","Cell line expression cluster":"Cluster 33: SK-MEL-30 - Melanocyte processes","Single cell expression cluster":"Cluster 63: NK-cells & T-cells - Immune response","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB026150":null,"CAB030007":"AB_2303380","HPA006404":"AB_1851348"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.39e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.48e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.53e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.01e-6"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.11e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.83e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.62e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.32e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.25e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.62e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.16e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.72e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.79e-6"},"Tissue RNA - adipose tissue [nTPM]":"37.0","Tissue RNA - adrenal gland [nTPM]":"71.8","Tissue RNA - amygdala [nTPM]":"2.4","Tissue RNA - appendix [nTPM]":"6.2","Tissue RNA - basal ganglia [nTPM]":"2.2","Tissue RNA - bone marrow [nTPM]":"5.0","Tissue RNA - breast [nTPM]":"34.8","Tissue RNA - cerebellum [nTPM]":"2.2","Tissue RNA - cerebral cortex [nTPM]":"6.6","Tissue RNA - cervix [nTPM]":"52.5","Tissue RNA - choroid plexus [nTPM]":"3.9","Tissue RNA - colon [nTPM]":"57.6","Tissue RNA - duodenum [nTPM]":"16.9","Tissue RNA - endometrium 1 [nTPM]":"32.9","Tissue RNA - epididymis [nTPM]":"1.2","Tissue RNA - esophagus [nTPM]":"26.4","Tissue RNA - fallopian tube [nTPM]":"39.9","Tissue RNA - gallbladder [nTPM]":"4.4","Tissue RNA - heart muscle [nTPM]":"23.8","Tissue RNA - hippocampal formation [nTPM]":"2.7","Tissue RNA - hypothalamus [nTPM]":"2.4","Tissue RNA - kidney [nTPM]":"57.1","Tissue RNA - liver [nTPM]":"61.8","Tissue RNA - lung [nTPM]":"58.0","Tissue RNA - lymph node [nTPM]":"10.0","Tissue RNA - medulla oblongata [nTPM]":"2.6","Tissue RNA - midbrain [nTPM]":"2.3","Tissue RNA - ovary [nTPM]":"33.0","Tissue RNA - pancreas [nTPM]":"20.4","Tissue RNA - parathyroid gland [nTPM]":"3.9","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"2.8","Tissue RNA - pons [nTPM]":"2.4","Tissue RNA - prostate [nTPM]":"50.4","Tissue RNA - rectum [nTPM]":"5.5","Tissue RNA - retina [nTPM]":"0.6","Tissue RNA - salivary gland [nTPM]":"35.3","Tissue RNA - seminal vesicle [nTPM]":"2.3","Tissue RNA - skeletal muscle [nTPM]":"6.5","Tissue RNA - skin 1 [nTPM]":"22.2","Tissue RNA - small intestine [nTPM]":"67.5","Tissue RNA - smooth muscle [nTPM]":"1.2","Tissue RNA - spinal cord [nTPM]":"2.1","Tissue RNA - spleen [nTPM]":"100.7","Tissue RNA - stomach 1 [nTPM]":"45.9","Tissue RNA - testis [nTPM]":"7.5","Tissue RNA - thalamus [nTPM]":"2.7","Tissue RNA - thymus [nTPM]":"2.8","Tissue RNA - thyroid gland [nTPM]":"29.4","Tissue RNA - tongue [nTPM]":"1.0","Tissue RNA - tonsil [nTPM]":"4.0","Tissue RNA - urinary bladder [nTPM]":"33.6","Tissue RNA - vagina [nTPM]":"37.3","Tissue RNA - white matter [nTPM]":"2.6","Cell RNA - A-431 [nTPM]":"0.6","Cell RNA - A549 [nTPM]":"0.3","Cell RNA - AF22 [nTPM]":"0.3","Cell RNA - AN3-CA [nTPM]":"8.7","Cell RNA - ASC diff [nTPM]":"2.3","Cell RNA - ASC TERT1 [nTPM]":"9.1","Cell RNA - BEWO [nTPM]":"2.7","Cell RNA - BJ [nTPM]":"2.5","Cell RNA - BJ hTERT+ [nTPM]":"8.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"6.5","Cell RNA - CACO-2 [nTPM]":"0.7","Cell RNA - CAPAN-2 [nTPM]":"6.3","Cell RNA - Daudi [nTPM]":"2.4","Cell RNA - EFO-21 [nTPM]":"0.5","Cell RNA - fHDF\/TERT166 [nTPM]":"7.7","Cell RNA - GAMG [nTPM]":"2.8","Cell RNA - HaCaT [nTPM]":"4.4","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"3.2","Cell RNA - HBF TERT88 [nTPM]":"0.7","Cell RNA - HDLM-2 [nTPM]":"11.4","Cell RNA - HEK 293 [nTPM]":"0.0","Cell RNA - HEL [nTPM]":"6.1","Cell RNA - HeLa [nTPM]":"0.8","Cell RNA - Hep G2 [nTPM]":"1.0","Cell RNA - HHSteC [nTPM]":"9.1","Cell RNA - HL-60 [nTPM]":"3.3","Cell RNA - HMC-1 [nTPM]":"6.8","Cell RNA - HSkMC [nTPM]":"4.4","Cell RNA - hTCEpi [nTPM]":"2.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"2.6","Cell RNA - hTERT-HME1 [nTPM]":"0.6","Cell RNA - hTERT-RPE1 [nTPM]":"4.3","Cell RNA - HUVEC TERT2 [nTPM]":"5.8","Cell RNA - JURKAT [nTPM]":"0.4","Cell RNA - K-562 [nTPM]":"1.9","Cell RNA - Karpas-707 [nTPM]":"11.9","Cell RNA - LHCN-M2 [nTPM]":"4.5","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"4.4","Cell RNA - NB-4 [nTPM]":"0.3","Cell RNA - NTERA-2 [nTPM]":"0.1","Cell RNA - OE19 [nTPM]":"2.4","Cell RNA - PC-3 [nTPM]":"4.4","Cell RNA - REH [nTPM]":"2.8","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.6","Cell RNA - RPTEC TERT1 [nTPM]":"0.4","Cell RNA - RT4 [nTPM]":"3.7","Cell RNA - SCLC-21H [nTPM]":"0.1","Cell RNA - SH-SY5Y [nTPM]":"0.2","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.4","Cell RNA - SK-MEL-30 [nTPM]":"16.2","Cell RNA - SuSa [nTPM]":"0.0","Cell RNA - T-47d [nTPM]":"1.5","Cell RNA - THP-1 [nTPM]":"0.7","Cell RNA - TIME [nTPM]":"5.9","Cell RNA - U-138 MG [nTPM]":"0.3","Cell RNA - U-2 OS [nTPM]":"1.8","Cell RNA - U-2197 [nTPM]":"0.8","Cell RNA - U-251 MG [nTPM]":"0.4","Cell RNA - U-266\/70 [nTPM]":"8.1","Cell RNA - U-266\/84 [nTPM]":"2.2","Cell RNA - U-698 [nTPM]":"1.2","Cell RNA - U-87 MG [nTPM]":"0.5","Cell RNA - U-937 [nTPM]":"2.7","Cell RNA - WM-115 [nTPM]":"1.5","Blood RNA - basophil [nTPM]":"2.2","Blood RNA - classical monocyte [nTPM]":"31.4","Blood RNA - eosinophil [nTPM]":"5.5","Blood RNA - gdT-cell [nTPM]":"40.2","Blood RNA - intermediate monocyte [nTPM]":"68.2","Blood RNA - MAIT T-cell [nTPM]":"23.3","Blood RNA - memory B-cell [nTPM]":"42.4","Blood RNA - memory CD4 T-cell [nTPM]":"47.2","Blood RNA - memory CD8 T-cell [nTPM]":"27.0","Blood RNA - myeloid DC [nTPM]":"23.2","Blood RNA - naive B-cell [nTPM]":"50.1","Blood RNA - naive CD4 T-cell [nTPM]":"51.3","Blood RNA - naive CD8 T-cell [nTPM]":"39.4","Blood RNA - neutrophil [nTPM]":"78.4","Blood RNA - NK-cell [nTPM]":"12.8","Blood RNA - non-classical monocyte [nTPM]":"50.9","Blood RNA - plasmacytoid DC [nTPM]":"33.2","Blood RNA - T-reg [nTPM]":"62.8","Blood RNA - total PBMC [nTPM]":"39.3","Brain RNA - amygdala [nTPM]":"2.4","Brain RNA - basal ganglia [nTPM]":"2.2","Brain RNA - cerebellum [nTPM]":"2.2","Brain RNA - cerebral cortex [nTPM]":"6.6","Brain RNA - hippocampal formation [nTPM]":"2.7","Brain RNA - hypothalamus [nTPM]":"2.4","Brain RNA - medulla oblongata [nTPM]":"2.6","Brain RNA - midbrain [nTPM]":"2.3","Brain RNA - pons [nTPM]":"2.4","Brain RNA - spinal cord [nTPM]":"2.1","Brain RNA - thalamus [nTPM]":"2.7","Brain RNA - white matter [nTPM]":"2.6","Single Cell Type RNA - Adipocytes [nTPM]":"63.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"38.0","Single Cell Type RNA - Astrocytes [nTPM]":"5.5","Single Cell Type RNA - B-cells [nTPM]":"97.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"16.4","Single Cell Type RNA - Basal prostatic cells [nTPM]":"31.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"50.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"23.3","Single Cell Type RNA - Bipolar cells [nTPM]":"1.5","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"33.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"8.3","Single Cell Type RNA - Cholangiocytes [nTPM]":"47.1","Single Cell Type RNA - Club cells [nTPM]":"51.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"35.0","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - dendritic cells [nTPM]":"90.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"94.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"3.9","Single Cell Type RNA - Ductal cells [nTPM]":"16.8","Single Cell Type RNA - Early spermatids [nTPM]":"0.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"19.9","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"18.4","Single Cell Type RNA - Endothelial cells [nTPM]":"52.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"36.1","Single Cell Type RNA - Erythroid cells [nTPM]":"18.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"32.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"1.5","Single Cell Type RNA - Fibroblasts [nTPM]":"27.1","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"77.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"25.8","Single Cell Type RNA - granulocytes [nTPM]":"53.2","Single Cell Type RNA - Granulosa cells [nTPM]":"8.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"41.4","Single Cell Type RNA - Hepatocytes [nTPM]":"20.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"88.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"78.4","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"80.1","Single Cell Type RNA - Langerhans cells [nTPM]":"59.3","Single Cell Type RNA - Late spermatids [nTPM]":"2.6","Single Cell Type RNA - Leydig cells [nTPM]":"20.8","Single Cell Type RNA - Macrophages [nTPM]":"91.3","Single Cell Type RNA - Melanocytes [nTPM]":"46.2","Single Cell Type RNA - Microglial cells [nTPM]":"17.8","Single Cell Type RNA - monocytes [nTPM]":"106.1","Single Cell Type RNA - Muller glia cells [nTPM]":"15.9","Single Cell Type RNA - NK-cells [nTPM]":"131.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"2.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"1.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"24.6","Single Cell Type RNA - Paneth cells [nTPM]":"115.8","Single Cell Type RNA - Peritubular cells [nTPM]":"13.9","Single Cell Type RNA - Plasma cells [nTPM]":"70.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"29.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"219.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"35.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"34.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.7","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"9.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"22.0","Single Cell Type RNA - Spermatocytes [nTPM]":"0.1","Single Cell Type RNA - Spermatogonia [nTPM]":"0.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"15.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"13.4","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"1.2","Single Cell Type RNA - T-cells [nTPM]":"84.4","Single Cell Type RNA - Theca cells [nTPM]":"16.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"101.4","Single Cell Type RNA - Urothelial cells [nTPM]":"44.3"},{"Gene":"TP53","Gene synonym":["LFS1","p53"],"Ensembl":"ENSG00000141510","Gene description":"Tumor protein p53","Uniprot":["P04637"],"Chromosome":"17","Position":"7661779-7687538","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transcription factors","Transporters"],"Biological process":["Apoptosis","Biological rhythms","Cell cycle","Host-virus interaction","Necrosis","Transcription","Transcription regulation"],"Molecular function":["Activator","DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Li-Fraumeni syndrome","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB002973","CAB039238","CAB039239","HPA051244","HPA063532","CAB072876","CAB079965"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: Non-specific - mRNA processing","Tissue expression cluster":"Cluster 3: T-cells - Adaptive immune response","Cell line expression cluster":"Cluster 14: REH - Unknown function","Single cell expression cluster":"Cluster 32: Non-specific - Translation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitochondria","Cytosol"],"Antibody RRID":{"CAB002973":"AB_2206626","CAB039238":null,"CAB039239":null,"CAB072876":"AB_2665731","CAB079965":null,"HPA051244":"AB_2681403","HPA063532":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.29e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.83e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"1.35e-4"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.95e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.00e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.79e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.99e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.75e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.55e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"5.01e-4"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"7.89e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.05e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.74e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Tissue RNA - adipose tissue [nTPM]":"19.3","Tissue RNA - adrenal gland [nTPM]":"13.8","Tissue RNA - amygdala [nTPM]":"10.4","Tissue RNA - appendix [nTPM]":"27.1","Tissue RNA - basal ganglia [nTPM]":"12.6","Tissue RNA - bone marrow [nTPM]":"19.6","Tissue RNA - breast [nTPM]":"22.5","Tissue RNA - cerebellum [nTPM]":"10.4","Tissue RNA - cerebral cortex [nTPM]":"16.5","Tissue RNA - cervix [nTPM]":"19.9","Tissue RNA - choroid plexus [nTPM]":"10.3","Tissue RNA - colon [nTPM]":"29.0","Tissue RNA - duodenum [nTPM]":"18.9","Tissue RNA - endometrium 1 [nTPM]":"24.5","Tissue RNA - epididymis [nTPM]":"12.8","Tissue RNA - esophagus [nTPM]":"28.8","Tissue RNA - fallopian tube [nTPM]":"31.3","Tissue RNA - gallbladder [nTPM]":"13.2","Tissue RNA - heart muscle [nTPM]":"11.1","Tissue RNA - hippocampal formation [nTPM]":"10.1","Tissue RNA - hypothalamus [nTPM]":"11.4","Tissue RNA - kidney [nTPM]":"14.9","Tissue RNA - liver [nTPM]":"16.5","Tissue RNA - lung [nTPM]":"15.1","Tissue RNA - lymph node [nTPM]":"34.6","Tissue RNA - medulla oblongata [nTPM]":"18.7","Tissue RNA - midbrain [nTPM]":"13.6","Tissue RNA - ovary [nTPM]":"27.3","Tissue RNA - pancreas [nTPM]":"18.3","Tissue RNA - parathyroid gland [nTPM]":"9.4","Tissue RNA - pituitary gland [nTPM]":"7.3","Tissue RNA - placenta [nTPM]":"23.5","Tissue RNA - pons [nTPM]":"12.5","Tissue RNA - prostate [nTPM]":"17.7","Tissue RNA - rectum [nTPM]":"27.5","Tissue RNA - retina [nTPM]":"4.1","Tissue RNA - salivary gland [nTPM]":"18.9","Tissue RNA - seminal vesicle [nTPM]":"15.3","Tissue RNA - skeletal muscle [nTPM]":"12.3","Tissue RNA - skin 1 [nTPM]":"37.4","Tissue RNA - small intestine [nTPM]":"20.4","Tissue RNA - smooth muscle [nTPM]":"24.6","Tissue RNA - spinal cord [nTPM]":"12.6","Tissue RNA - spleen [nTPM]":"31.1","Tissue RNA - stomach 1 [nTPM]":"22.6","Tissue RNA - testis [nTPM]":"10.4","Tissue RNA - thalamus [nTPM]":"12.3","Tissue RNA - thymus [nTPM]":"47.2","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"6.1","Tissue RNA - tonsil [nTPM]":"45.4","Tissue RNA - urinary bladder [nTPM]":"20.8","Tissue RNA - vagina [nTPM]":"19.9","Tissue RNA - white matter [nTPM]":"13.3","Cell RNA - A-431 [nTPM]":"81.5","Cell RNA - A549 [nTPM]":"145.3","Cell RNA - AF22 [nTPM]":"81.1","Cell RNA - AN3-CA [nTPM]":"57.3","Cell RNA - ASC diff [nTPM]":"37.3","Cell RNA - ASC TERT1 [nTPM]":"43.9","Cell RNA - BEWO [nTPM]":"82.8","Cell RNA - BJ [nTPM]":"28.4","Cell RNA - BJ hTERT+ [nTPM]":"66.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"78.5","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"100.2","Cell RNA - CACO-2 [nTPM]":"4.2","Cell RNA - CAPAN-2 [nTPM]":"40.6","Cell RNA - Daudi [nTPM]":"190.5","Cell RNA - EFO-21 [nTPM]":"126.9","Cell RNA - fHDF\/TERT166 [nTPM]":"58.7","Cell RNA - GAMG [nTPM]":"77.6","Cell RNA - HaCaT [nTPM]":"174.9","Cell RNA - HAP1 [nTPM]":"119.7","Cell RNA - HBEC3-KT [nTPM]":"80.4","Cell RNA - HBF TERT88 [nTPM]":"72.8","Cell RNA - HDLM-2 [nTPM]":"42.7","Cell RNA - HEK 293 [nTPM]":"76.5","Cell RNA - HEL [nTPM]":"77.6","Cell RNA - HeLa [nTPM]":"76.8","Cell RNA - Hep G2 [nTPM]":"70.9","Cell RNA - HHSteC [nTPM]":"111.5","Cell RNA - HL-60 [nTPM]":"1.6","Cell RNA - HMC-1 [nTPM]":"37.0","Cell RNA - HSkMC [nTPM]":"55.7","Cell RNA - hTCEpi [nTPM]":"93.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"38.9","Cell RNA - hTERT-HME1 [nTPM]":"106.5","Cell RNA - hTERT-RPE1 [nTPM]":"45.6","Cell RNA - HUVEC TERT2 [nTPM]":"79.4","Cell RNA - JURKAT [nTPM]":"24.7","Cell RNA - K-562 [nTPM]":"3.8","Cell RNA - Karpas-707 [nTPM]":"6.9","Cell RNA - LHCN-M2 [nTPM]":"41.5","Cell RNA - MCF7 [nTPM]":"145.1","Cell RNA - MOLT-4 [nTPM]":"130.0","Cell RNA - NB-4 [nTPM]":"96.3","Cell RNA - NTERA-2 [nTPM]":"80.2","Cell RNA - OE19 [nTPM]":"10.4","Cell RNA - PC-3 [nTPM]":"2.4","Cell RNA - REH [nTPM]":"252.2","Cell RNA - RH-30 [nTPM]":"56.1","Cell RNA - RPMI-8226 [nTPM]":"66.2","Cell RNA - RPTEC TERT1 [nTPM]":"59.4","Cell RNA - RT4 [nTPM]":"87.3","Cell RNA - SCLC-21H [nTPM]":"46.0","Cell RNA - SH-SY5Y [nTPM]":"80.5","Cell RNA - SiHa [nTPM]":"94.1","Cell RNA - SK-BR-3 [nTPM]":"62.6","Cell RNA - SK-MEL-30 [nTPM]":"24.3","Cell RNA - SuSa [nTPM]":"39.4","Cell RNA - T-47d [nTPM]":"109.2","Cell RNA - THP-1 [nTPM]":"7.4","Cell RNA - TIME [nTPM]":"100.7","Cell RNA - U-138 MG [nTPM]":"91.6","Cell RNA - U-2 OS [nTPM]":"30.2","Cell RNA - U-2197 [nTPM]":"1.0","Cell RNA - U-251 MG [nTPM]":"48.3","Cell RNA - U-266\/70 [nTPM]":"47.6","Cell RNA - U-266\/84 [nTPM]":"37.9","Cell RNA - U-698 [nTPM]":"82.5","Cell RNA - U-87 MG [nTPM]":"23.6","Cell RNA - U-937 [nTPM]":"9.7","Cell RNA - WM-115 [nTPM]":"80.1","Blood RNA - basophil [nTPM]":"1.2","Blood RNA - classical monocyte [nTPM]":"21.2","Blood RNA - eosinophil [nTPM]":"3.4","Blood RNA - gdT-cell [nTPM]":"13.0","Blood RNA - intermediate monocyte [nTPM]":"21.7","Blood RNA - MAIT T-cell [nTPM]":"15.9","Blood RNA - memory B-cell [nTPM]":"21.5","Blood RNA - memory CD4 T-cell [nTPM]":"13.3","Blood RNA - memory CD8 T-cell [nTPM]":"14.6","Blood RNA - myeloid DC [nTPM]":"30.3","Blood RNA - naive B-cell [nTPM]":"19.1","Blood RNA - naive CD4 T-cell [nTPM]":"13.7","Blood RNA - naive CD8 T-cell [nTPM]":"15.4","Blood RNA - neutrophil [nTPM]":"2.4","Blood RNA - NK-cell [nTPM]":"17.5","Blood RNA - non-classical monocyte [nTPM]":"19.3","Blood RNA - plasmacytoid DC [nTPM]":"27.3","Blood RNA - T-reg [nTPM]":"17.3","Blood RNA - total PBMC [nTPM]":"14.7","Brain RNA - amygdala [nTPM]":"10.4","Brain RNA - basal ganglia [nTPM]":"12.6","Brain RNA - cerebellum [nTPM]":"10.4","Brain RNA - cerebral cortex [nTPM]":"16.5","Brain RNA - hippocampal formation [nTPM]":"10.1","Brain RNA - hypothalamus [nTPM]":"11.4","Brain RNA - medulla oblongata [nTPM]":"18.7","Brain RNA - midbrain [nTPM]":"13.6","Brain RNA - pons [nTPM]":"12.5","Brain RNA - spinal cord [nTPM]":"12.6","Brain RNA - thalamus [nTPM]":"12.3","Brain RNA - white matter [nTPM]":"13.3","Single Cell Type RNA - Adipocytes [nTPM]":"21.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.8","Single Cell Type RNA - Astrocytes [nTPM]":"16.3","Single Cell Type RNA - B-cells [nTPM]":"26.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"14.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"24.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"2.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"36.1","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"30.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"2.5","Single Cell Type RNA - Cholangiocytes [nTPM]":"18.6","Single Cell Type RNA - Club cells [nTPM]":"15.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"36.9","Single Cell Type RNA - dendritic cells [nTPM]":"24.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"24.8","Single Cell Type RNA - Early spermatids [nTPM]":"12.8","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"11.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"29.0","Single Cell Type RNA - Endothelial cells [nTPM]":"24.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"30.7","Single Cell Type RNA - Erythroid cells [nTPM]":"21.7","Single Cell Type RNA - Excitatory neurons [nTPM]":"2.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"18.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"39.6","Single Cell Type RNA - Fibroblasts [nTPM]":"17.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.2","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.5","Single Cell Type RNA - granulocytes [nTPM]":"1.3","Single Cell Type RNA - Granulosa cells [nTPM]":"31.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"18.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"24.2","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"3.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"43.0","Single Cell Type RNA - Ionocytes [nTPM]":"18.3","Single Cell Type RNA - Kupffer cells [nTPM]":"27.8","Single Cell Type RNA - Langerhans cells [nTPM]":"20.1","Single Cell Type RNA - Late spermatids [nTPM]":"3.8","Single Cell Type RNA - Leydig cells [nTPM]":"23.0","Single Cell Type RNA - Macrophages [nTPM]":"19.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"4.9","Single Cell Type RNA - NK-cells [nTPM]":"25.7","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"9.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"8.0","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"15.8","Single Cell Type RNA - Paneth cells [nTPM]":"16.4","Single Cell Type RNA - Peritubular cells [nTPM]":"17.0","Single Cell Type RNA - Plasma cells [nTPM]":"7.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"15.7","Single Cell Type RNA - Proximal enterocytes [nTPM]":"10.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"10.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"8.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"2.6","Single Cell Type RNA - Sertoli cells [nTPM]":"13.1","Single Cell Type RNA - Skeletal myocytes [nTPM]":"25.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"20.6","Single Cell Type RNA - Spermatocytes [nTPM]":"0.5","Single Cell Type RNA - Spermatogonia [nTPM]":"4.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"28.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"22.4","Single Cell Type RNA - T-cells [nTPM]":"16.5","Single Cell Type RNA - Theca cells [nTPM]":"27.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"54.1","Single Cell Type RNA - Urothelial cells [nTPM]":"11.5"},{"Gene":"TPM3","Gene synonym":["NEM1","TRK"],"Ensembl":"ENSG00000143549","Gene description":"Tropomyosin 3","Uniprot":["P06753"],"Chromosome":"1","Position":"154155304-154194648","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Muscle protein"],"Disease involvement":["Cancer-related genes","Disease variant","Nemaline myopathy","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"13","RNA tissue specific nTPM":{"skeletal muscle":"8905.8","tongue":"6106.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA000261","HPA009066","HPA047089","HPA053624"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Actin filaments","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"170000000","Blood expression cluster":"Cluster 45: Eosinophils - Innate immune response","Tissue expression cluster":"Cluster 13: Striated muscle - Muscle contraction","Cell line expression cluster":"Cluster 17: WM-115 - Nervous system development","Single cell expression cluster":"Cluster 11: Alveolar cells - Smell perception","Subcellular main location":["Actin filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA000261":"AB_1080339","HPA009066":"AB_1080342","HPA047089":"AB_2679928","HPA053624":"AB_2682210"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.64e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.11e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.01e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.07e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.39e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.69e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"6.73e-6"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.01e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.80e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.39e-5"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.65e-4"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.31e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"3.12e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.98e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-2"},"Tissue RNA - adipose tissue [nTPM]":"140.7","Tissue RNA - adrenal gland [nTPM]":"103.2","Tissue RNA - amygdala [nTPM]":"95.0","Tissue RNA - appendix [nTPM]":"233.2","Tissue RNA - basal ganglia [nTPM]":"104.1","Tissue RNA - bone marrow [nTPM]":"590.1","Tissue RNA - breast [nTPM]":"97.1","Tissue RNA - cerebellum [nTPM]":"83.3","Tissue RNA - cerebral cortex [nTPM]":"116.2","Tissue RNA - cervix [nTPM]":"94.9","Tissue RNA - choroid plexus [nTPM]":"73.3","Tissue RNA - colon [nTPM]":"199.0","Tissue RNA - duodenum [nTPM]":"163.5","Tissue RNA - endometrium 1 [nTPM]":"69.6","Tissue RNA - epididymis [nTPM]":"73.4","Tissue RNA - esophagus [nTPM]":"287.4","Tissue RNA - fallopian tube [nTPM]":"100.6","Tissue RNA - gallbladder [nTPM]":"136.1","Tissue RNA - heart muscle [nTPM]":"318.5","Tissue RNA - hippocampal formation [nTPM]":"104.8","Tissue RNA - hypothalamus [nTPM]":"101.5","Tissue RNA - kidney [nTPM]":"81.5","Tissue RNA - liver [nTPM]":"114.4","Tissue RNA - lung [nTPM]":"178.7","Tissue RNA - lymph node [nTPM]":"287.3","Tissue RNA - medulla oblongata [nTPM]":"96.6","Tissue RNA - midbrain [nTPM]":"101.4","Tissue RNA - ovary [nTPM]":"45.4","Tissue RNA - pancreas [nTPM]":"265.9","Tissue RNA - parathyroid gland [nTPM]":"91.7","Tissue RNA - pituitary gland [nTPM]":"19.6","Tissue RNA - placenta [nTPM]":"141.1","Tissue RNA - pons [nTPM]":"101.6","Tissue RNA - prostate [nTPM]":"122.3","Tissue RNA - rectum [nTPM]":"201.5","Tissue RNA - retina [nTPM]":"60.3","Tissue RNA - salivary gland [nTPM]":"101.5","Tissue RNA - seminal vesicle [nTPM]":"56.0","Tissue RNA - skeletal muscle [nTPM]":"8905.8","Tissue RNA - skin 1 [nTPM]":"103.0","Tissue RNA - small intestine [nTPM]":"167.8","Tissue RNA - smooth muscle [nTPM]":"111.6","Tissue RNA - spinal cord [nTPM]":"94.6","Tissue RNA - spleen [nTPM]":"208.9","Tissue RNA - stomach 1 [nTPM]":"152.8","Tissue RNA - testis [nTPM]":"64.8","Tissue RNA - thalamus [nTPM]":"93.8","Tissue RNA - thymus [nTPM]":"203.0","Tissue RNA - thyroid gland [nTPM]":"88.8","Tissue RNA - tongue [nTPM]":"6106.5","Tissue RNA - tonsil [nTPM]":"287.2","Tissue RNA - urinary bladder [nTPM]":"183.2","Tissue RNA - vagina [nTPM]":"29.7","Tissue RNA - white matter [nTPM]":"98.2","Cell RNA - A-431 [nTPM]":"529.4","Cell RNA - A549 [nTPM]":"332.8","Cell RNA - AF22 [nTPM]":"306.1","Cell RNA - AN3-CA [nTPM]":"225.4","Cell RNA - ASC diff [nTPM]":"262.1","Cell RNA - ASC TERT1 [nTPM]":"341.1","Cell RNA - BEWO [nTPM]":"317.9","Cell RNA - BJ [nTPM]":"439.0","Cell RNA - BJ hTERT+ [nTPM]":"419.1","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"597.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"437.7","Cell RNA - CACO-2 [nTPM]":"596.1","Cell RNA - CAPAN-2 [nTPM]":"513.9","Cell RNA - Daudi [nTPM]":"414.6","Cell RNA - EFO-21 [nTPM]":"366.9","Cell RNA - fHDF\/TERT166 [nTPM]":"500.2","Cell RNA - GAMG [nTPM]":"206.4","Cell RNA - HaCaT [nTPM]":"472.1","Cell RNA - HAP1 [nTPM]":"320.0","Cell RNA - HBEC3-KT [nTPM]":"468.7","Cell RNA - HBF TERT88 [nTPM]":"485.8","Cell RNA - HDLM-2 [nTPM]":"315.7","Cell RNA - HEK 293 [nTPM]":"171.9","Cell RNA - HEL [nTPM]":"537.6","Cell RNA - HeLa [nTPM]":"234.1","Cell RNA - Hep G2 [nTPM]":"311.7","Cell RNA - HHSteC [nTPM]":"200.9","Cell RNA - HL-60 [nTPM]":"728.2","Cell RNA - HMC-1 [nTPM]":"627.5","Cell RNA - HSkMC [nTPM]":"260.0","Cell RNA - hTCEpi [nTPM]":"246.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"515.8","Cell RNA - hTERT-HME1 [nTPM]":"355.1","Cell RNA - hTERT-RPE1 [nTPM]":"224.9","Cell RNA - HUVEC TERT2 [nTPM]":"929.4","Cell RNA - JURKAT [nTPM]":"269.0","Cell RNA - K-562 [nTPM]":"411.8","Cell RNA - Karpas-707 [nTPM]":"429.7","Cell RNA - LHCN-M2 [nTPM]":"710.0","Cell RNA - MCF7 [nTPM]":"342.2","Cell RNA - MOLT-4 [nTPM]":"582.0","Cell RNA - NB-4 [nTPM]":"683.1","Cell RNA - NTERA-2 [nTPM]":"714.2","Cell RNA - OE19 [nTPM]":"775.9","Cell RNA - PC-3 [nTPM]":"515.9","Cell RNA - REH [nTPM]":"510.0","Cell RNA - RH-30 [nTPM]":"233.2","Cell RNA - RPMI-8226 [nTPM]":"574.9","Cell RNA - RPTEC TERT1 [nTPM]":"405.6","Cell RNA - RT4 [nTPM]":"387.4","Cell RNA - SCLC-21H [nTPM]":"234.4","Cell RNA - SH-SY5Y [nTPM]":"409.4","Cell RNA - SiHa [nTPM]":"360.0","Cell RNA - SK-BR-3 [nTPM]":"443.7","Cell RNA - SK-MEL-30 [nTPM]":"419.2","Cell RNA - SuSa [nTPM]":"303.9","Cell RNA - T-47d [nTPM]":"645.0","Cell RNA - THP-1 [nTPM]":"788.9","Cell RNA - TIME [nTPM]":"758.8","Cell RNA - U-138 MG [nTPM]":"558.8","Cell RNA - U-2 OS [nTPM]":"353.9","Cell RNA - U-2197 [nTPM]":"497.3","Cell RNA - U-251 MG [nTPM]":"711.1","Cell RNA - U-266\/70 [nTPM]":"332.4","Cell RNA - U-266\/84 [nTPM]":"623.0","Cell RNA - U-698 [nTPM]":"516.2","Cell RNA - U-87 MG [nTPM]":"490.7","Cell RNA - U-937 [nTPM]":"514.7","Cell RNA - WM-115 [nTPM]":"860.0","Blood RNA - basophil [nTPM]":"932.1","Blood RNA - classical monocyte [nTPM]":"743.2","Blood RNA - eosinophil [nTPM]":"1729.3","Blood RNA - gdT-cell [nTPM]":"547.2","Blood RNA - intermediate monocyte [nTPM]":"945.6","Blood RNA - MAIT T-cell [nTPM]":"480.1","Blood RNA - memory B-cell [nTPM]":"395.2","Blood RNA - memory CD4 T-cell [nTPM]":"464.0","Blood RNA - memory CD8 T-cell [nTPM]":"504.4","Blood RNA - myeloid DC [nTPM]":"792.6","Blood RNA - naive B-cell [nTPM]":"324.5","Blood RNA - naive CD4 T-cell [nTPM]":"347.2","Blood RNA - naive CD8 T-cell [nTPM]":"442.6","Blood RNA - neutrophil [nTPM]":"824.3","Blood RNA - NK-cell [nTPM]":"386.4","Blood RNA - non-classical monocyte [nTPM]":"1104.4","Blood RNA - plasmacytoid DC [nTPM]":"392.9","Blood RNA - T-reg [nTPM]":"551.5","Blood RNA - total PBMC [nTPM]":"2029.4","Brain RNA - amygdala [nTPM]":"95.0","Brain RNA - basal ganglia [nTPM]":"104.1","Brain RNA - cerebellum [nTPM]":"83.3","Brain RNA - cerebral cortex [nTPM]":"116.2","Brain RNA - hippocampal formation [nTPM]":"104.8","Brain RNA - hypothalamus [nTPM]":"101.5","Brain RNA - medulla oblongata [nTPM]":"96.6","Brain RNA - midbrain [nTPM]":"101.4","Brain RNA - pons [nTPM]":"101.6","Brain RNA - spinal cord [nTPM]":"94.6","Brain RNA - thalamus [nTPM]":"93.8","Brain RNA - white matter [nTPM]":"98.2","Single Cell Type RNA - Adipocytes [nTPM]":"346.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"621.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"343.2","Single Cell Type RNA - Astrocytes [nTPM]":"17.6","Single Cell Type RNA - B-cells [nTPM]":"318.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"149.5","Single Cell Type RNA - Basal prostatic cells [nTPM]":"227.6","Single Cell Type RNA - Basal respiratory cells [nTPM]":"169.5","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"127.5","Single Cell Type RNA - Bipolar cells [nTPM]":"84.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"135.4","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"88.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"85.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"125.8","Single Cell Type RNA - Club cells [nTPM]":"275.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"97.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"31.3","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"127.3","Single Cell Type RNA - dendritic cells [nTPM]":"475.7","Single Cell Type RNA - Distal enterocytes [nTPM]":"494.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"105.7","Single Cell Type RNA - Ductal cells [nTPM]":"292.1","Single Cell Type RNA - Early spermatids [nTPM]":"72.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"353.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"191.1","Single Cell Type RNA - Endothelial cells [nTPM]":"395.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"141.0","Single Cell Type RNA - Erythroid cells [nTPM]":"189.8","Single Cell Type RNA - Excitatory neurons [nTPM]":"65.7","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"347.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"331.0","Single Cell Type RNA - Fibroblasts [nTPM]":"170.4","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"245.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"474.2","Single Cell Type RNA - granulocytes [nTPM]":"531.3","Single Cell Type RNA - Granulosa cells [nTPM]":"119.5","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"200.3","Single Cell Type RNA - Hepatocytes [nTPM]":"110.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"559.1","Single Cell Type RNA - Horizontal cells [nTPM]":"304.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"50.5","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"291.2","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"355.6","Single Cell Type RNA - Langerhans cells [nTPM]":"504.7","Single Cell Type RNA - Late spermatids [nTPM]":"182.3","Single Cell Type RNA - Leydig cells [nTPM]":"46.6","Single Cell Type RNA - Macrophages [nTPM]":"648.3","Single Cell Type RNA - Melanocytes [nTPM]":"152.9","Single Cell Type RNA - Microglial cells [nTPM]":"31.9","Single Cell Type RNA - monocytes [nTPM]":"704.0","Single Cell Type RNA - Muller glia cells [nTPM]":"54.5","Single Cell Type RNA - NK-cells [nTPM]":"466.5","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.5","Single Cell Type RNA - Oligodendrocytes [nTPM]":"30.6","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"530.4","Single Cell Type RNA - Paneth cells [nTPM]":"363.9","Single Cell Type RNA - Peritubular cells [nTPM]":"29.7","Single Cell Type RNA - Plasma cells [nTPM]":"218.2","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"204.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"220.1","Single Cell Type RNA - Proximal tubular cells [nTPM]":"179.8","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"230.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"62.8","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"155.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"128.5","Single Cell Type RNA - Spermatocytes [nTPM]":"38.6","Single Cell Type RNA - Spermatogonia [nTPM]":"67.6","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"223.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"143.3","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"101.9","Single Cell Type RNA - T-cells [nTPM]":"422.6","Single Cell Type RNA - Theca cells [nTPM]":"119.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"302.1","Single Cell Type RNA - Urothelial cells [nTPM]":"324.6"},{"Gene":"TPR","Gene synonym":[],"Ensembl":"ENSG00000047410","Gene description":"Translocated promoter region, nuclear basket protein","Uniprot":["P12270"],"Chromosome":"1","Position":"186311652-186375693","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins","Transporters"],"Biological process":["Cell cycle","Cell division","Mitosis","mRNA transport","Protein transport","Translocation","Transport"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Spermatocytes":"772.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA019661","HPA019663","HPA024336"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"30000000","Blood expression cluster":"Cluster 6: Non-specific - Transcription","Tissue expression cluster":"Cluster 48: Parathyroid gland - membrane proteins","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis","Subcellular main location":["Nuclear membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA019661":"AB_1858215","HPA019663":"AB_1858216","HPA024336":"AB_1858217"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.51e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.87e-3"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.48e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.56e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.88e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"4.71e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.06e-4"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.71e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.71e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.14e-1"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.45e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.63e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-3"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.75e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.19e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.06e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-2"},"Tissue RNA - adipose tissue [nTPM]":"19.8","Tissue RNA - adrenal gland [nTPM]":"14.5","Tissue RNA - amygdala [nTPM]":"12.2","Tissue RNA - appendix [nTPM]":"23.4","Tissue RNA - basal ganglia [nTPM]":"14.1","Tissue RNA - bone marrow [nTPM]":"28.9","Tissue RNA - breast [nTPM]":"19.7","Tissue RNA - cerebellum [nTPM]":"14.4","Tissue RNA - cerebral cortex [nTPM]":"10.9","Tissue RNA - cervix [nTPM]":"17.6","Tissue RNA - choroid plexus [nTPM]":"18.4","Tissue RNA - colon [nTPM]":"17.6","Tissue RNA - duodenum [nTPM]":"15.5","Tissue RNA - endometrium 1 [nTPM]":"20.3","Tissue RNA - epididymis [nTPM]":"19.7","Tissue RNA - esophagus [nTPM]":"14.8","Tissue RNA - fallopian tube [nTPM]":"15.0","Tissue RNA - gallbladder [nTPM]":"16.1","Tissue RNA - heart muscle [nTPM]":"17.1","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"12.9","Tissue RNA - kidney [nTPM]":"16.0","Tissue RNA - liver [nTPM]":"15.4","Tissue RNA - lung [nTPM]":"18.0","Tissue RNA - lymph node [nTPM]":"26.0","Tissue RNA - medulla oblongata [nTPM]":"13.6","Tissue RNA - midbrain [nTPM]":"12.0","Tissue RNA - ovary [nTPM]":"23.1","Tissue RNA - pancreas [nTPM]":"15.5","Tissue RNA - parathyroid gland [nTPM]":"34.2","Tissue RNA - pituitary gland [nTPM]":"13.4","Tissue RNA - placenta [nTPM]":"26.7","Tissue RNA - pons [nTPM]":"13.8","Tissue RNA - prostate [nTPM]":"17.2","Tissue RNA - rectum [nTPM]":"20.0","Tissue RNA - retina [nTPM]":"19.8","Tissue RNA - salivary gland [nTPM]":"15.8","Tissue RNA - seminal vesicle [nTPM]":"17.6","Tissue RNA - skeletal muscle [nTPM]":"20.4","Tissue RNA - skin 1 [nTPM]":"24.2","Tissue RNA - small intestine [nTPM]":"19.3","Tissue RNA - smooth muscle [nTPM]":"17.6","Tissue RNA - spinal cord [nTPM]":"12.2","Tissue RNA - spleen [nTPM]":"22.9","Tissue RNA - stomach 1 [nTPM]":"19.1","Tissue RNA - testis [nTPM]":"43.8","Tissue RNA - thalamus [nTPM]":"13.3","Tissue RNA - thymus [nTPM]":"31.0","Tissue RNA - thyroid gland [nTPM]":"22.7","Tissue RNA - tongue [nTPM]":"22.3","Tissue RNA - tonsil [nTPM]":"26.0","Tissue RNA - urinary bladder [nTPM]":"19.6","Tissue RNA - vagina [nTPM]":"14.5","Tissue RNA - white matter [nTPM]":"15.1","Cell RNA - A-431 [nTPM]":"55.9","Cell RNA - A549 [nTPM]":"46.7","Cell RNA - AF22 [nTPM]":"68.2","Cell RNA - AN3-CA [nTPM]":"39.8","Cell RNA - ASC diff [nTPM]":"53.4","Cell RNA - ASC TERT1 [nTPM]":"47.4","Cell RNA - BEWO [nTPM]":"73.2","Cell RNA - BJ [nTPM]":"62.0","Cell RNA - BJ hTERT+ [nTPM]":"41.2","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"42.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"40.4","Cell RNA - CACO-2 [nTPM]":"70.5","Cell RNA - CAPAN-2 [nTPM]":"45.9","Cell RNA - Daudi [nTPM]":"64.0","Cell RNA - EFO-21 [nTPM]":"47.1","Cell RNA - fHDF\/TERT166 [nTPM]":"42.1","Cell RNA - GAMG [nTPM]":"29.4","Cell RNA - HaCaT [nTPM]":"70.9","Cell RNA - HAP1 [nTPM]":"51.9","Cell RNA - HBEC3-KT [nTPM]":"42.4","Cell RNA - HBF TERT88 [nTPM]":"52.1","Cell RNA - HDLM-2 [nTPM]":"51.8","Cell RNA - HEK 293 [nTPM]":"58.6","Cell RNA - HEL [nTPM]":"86.8","Cell RNA - HeLa [nTPM]":"78.3","Cell RNA - Hep G2 [nTPM]":"49.7","Cell RNA - HHSteC [nTPM]":"28.7","Cell RNA - HL-60 [nTPM]":"93.1","Cell RNA - HMC-1 [nTPM]":"53.5","Cell RNA - HSkMC [nTPM]":"36.4","Cell RNA - hTCEpi [nTPM]":"25.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"64.4","Cell RNA - hTERT-HME1 [nTPM]":"49.4","Cell RNA - hTERT-RPE1 [nTPM]":"39.3","Cell RNA - HUVEC TERT2 [nTPM]":"51.3","Cell RNA - JURKAT [nTPM]":"36.5","Cell RNA - K-562 [nTPM]":"106.0","Cell RNA - Karpas-707 [nTPM]":"57.3","Cell RNA - LHCN-M2 [nTPM]":"45.8","Cell RNA - MCF7 [nTPM]":"47.5","Cell RNA - MOLT-4 [nTPM]":"46.2","Cell RNA - NB-4 [nTPM]":"24.5","Cell RNA - NTERA-2 [nTPM]":"76.1","Cell RNA - OE19 [nTPM]":"49.9","Cell RNA - PC-3 [nTPM]":"16.0","Cell RNA - REH [nTPM]":"54.3","Cell RNA - RH-30 [nTPM]":"54.3","Cell RNA - RPMI-8226 [nTPM]":"56.5","Cell RNA - RPTEC TERT1 [nTPM]":"34.8","Cell RNA - RT4 [nTPM]":"65.0","Cell RNA - SCLC-21H [nTPM]":"37.7","Cell RNA - SH-SY5Y [nTPM]":"59.5","Cell RNA - SiHa [nTPM]":"72.9","Cell RNA - SK-BR-3 [nTPM]":"47.1","Cell RNA - SK-MEL-30 [nTPM]":"37.6","Cell RNA - SuSa [nTPM]":"92.5","Cell RNA - T-47d [nTPM]":"53.1","Cell RNA - THP-1 [nTPM]":"58.0","Cell RNA - TIME [nTPM]":"73.0","Cell RNA - U-138 MG [nTPM]":"42.5","Cell RNA - U-2 OS [nTPM]":"40.6","Cell RNA - U-2197 [nTPM]":"47.7","Cell RNA - U-251 MG [nTPM]":"76.6","Cell RNA - U-266\/70 [nTPM]":"63.2","Cell RNA - U-266\/84 [nTPM]":"77.6","Cell RNA - U-698 [nTPM]":"57.0","Cell RNA - U-87 MG [nTPM]":"27.5","Cell RNA - U-937 [nTPM]":"45.8","Cell RNA - WM-115 [nTPM]":"38.7","Blood RNA - basophil [nTPM]":"121.4","Blood RNA - classical monocyte [nTPM]":"34.1","Blood RNA - eosinophil [nTPM]":"69.0","Blood RNA - gdT-cell [nTPM]":"43.8","Blood RNA - intermediate monocyte [nTPM]":"30.0","Blood RNA - MAIT T-cell [nTPM]":"37.7","Blood RNA - memory B-cell [nTPM]":"48.9","Blood RNA - memory CD4 T-cell [nTPM]":"38.6","Blood RNA - memory CD8 T-cell [nTPM]":"36.8","Blood RNA - myeloid DC [nTPM]":"20.6","Blood RNA - naive B-cell [nTPM]":"55.4","Blood RNA - naive CD4 T-cell [nTPM]":"47.3","Blood RNA - naive CD8 T-cell [nTPM]":"32.8","Blood RNA - neutrophil [nTPM]":"145.7","Blood RNA - NK-cell [nTPM]":"33.0","Blood RNA - non-classical monocyte [nTPM]":"50.4","Blood RNA - plasmacytoid DC [nTPM]":"58.7","Blood RNA - T-reg [nTPM]":"49.1","Blood RNA - total PBMC [nTPM]":"17.3","Brain RNA - amygdala [nTPM]":"12.2","Brain RNA - basal ganglia [nTPM]":"14.1","Brain RNA - cerebellum [nTPM]":"14.4","Brain RNA - cerebral cortex [nTPM]":"10.9","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"12.9","Brain RNA - medulla oblongata [nTPM]":"13.6","Brain RNA - midbrain [nTPM]":"12.0","Brain RNA - pons [nTPM]":"13.8","Brain RNA - spinal cord [nTPM]":"12.2","Brain RNA - thalamus [nTPM]":"13.3","Brain RNA - white matter [nTPM]":"15.1","Single Cell Type RNA - Adipocytes [nTPM]":"126.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"218.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"119.6","Single Cell Type RNA - Astrocytes [nTPM]":"43.1","Single Cell Type RNA - B-cells [nTPM]":"122.9","Single Cell Type RNA - Basal keratinocytes [nTPM]":"101.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"105.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"98.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"114.9","Single Cell Type RNA - Bipolar cells [nTPM]":"89.8","Single Cell Type RNA - Breast glandular cells [nTPM]":"65.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"79.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"180.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"54.3","Single Cell Type RNA - Club cells [nTPM]":"110.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"58.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"79.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"136.9","Single Cell Type RNA - dendritic cells [nTPM]":"136.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"51.2","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"107.1","Single Cell Type RNA - Early spermatids [nTPM]":"199.3","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"129.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"151.7","Single Cell Type RNA - Endothelial cells [nTPM]":"123.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"67.7","Single Cell Type RNA - Erythroid cells [nTPM]":"102.4","Single Cell Type RNA - Excitatory neurons [nTPM]":"42.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"74.7","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"99.9","Single Cell Type RNA - Fibroblasts [nTPM]":"126.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"80.5","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"134.4","Single Cell Type RNA - granulocytes [nTPM]":"81.0","Single Cell Type RNA - Granulosa cells [nTPM]":"134.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"74.6","Single Cell Type RNA - Hepatocytes [nTPM]":"40.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"72.8","Single Cell Type RNA - Horizontal cells [nTPM]":"99.3","Single Cell Type RNA - Inhibitory neurons [nTPM]":"42.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"61.9","Single Cell Type RNA - Ionocytes [nTPM]":"93.6","Single Cell Type RNA - Kupffer cells [nTPM]":"64.2","Single Cell Type RNA - Langerhans cells [nTPM]":"79.3","Single Cell Type RNA - Late spermatids [nTPM]":"50.4","Single Cell Type RNA - Leydig cells [nTPM]":"125.6","Single Cell Type RNA - Macrophages [nTPM]":"92.6","Single Cell Type RNA - Melanocytes [nTPM]":"55.2","Single Cell Type RNA - Microglial cells [nTPM]":"39.4","Single Cell Type RNA - monocytes [nTPM]":"137.3","Single Cell Type RNA - Muller glia cells [nTPM]":"101.1","Single Cell Type RNA - NK-cells [nTPM]":"139.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"48.2","Single Cell Type RNA - Oligodendrocytes [nTPM]":"62.8","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"90.1","Single Cell Type RNA - Paneth cells [nTPM]":"56.7","Single Cell Type RNA - Peritubular cells [nTPM]":"117.4","Single Cell Type RNA - Plasma cells [nTPM]":"113.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"95.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"52.4","Single Cell Type RNA - Proximal tubular cells [nTPM]":"27.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"120.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"111.4","Single Cell Type RNA - Sertoli cells [nTPM]":"131.5","Single Cell Type RNA - Skeletal myocytes [nTPM]":"172.5","Single Cell Type RNA - Smooth muscle cells [nTPM]":"152.1","Single Cell Type RNA - Spermatocytes [nTPM]":"772.9","Single Cell Type RNA - Spermatogonia [nTPM]":"250.4","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"85.6","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"99.2","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"150.8","Single Cell Type RNA - T-cells [nTPM]":"145.8","Single Cell Type RNA - Theca cells [nTPM]":"160.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"77.7","Single Cell Type RNA - Urothelial cells [nTPM]":"96.0"},{"Gene":"TRAF7","Gene synonym":["DKFZp586I021","MGC7807","RFWD1","RNF119"],"Ensembl":"ENSG00000131653","Gene description":"TNF receptor associated factor 7","Uniprot":["Q6Q0C0"],"Chromosome":"16","Position":"2155698-2178129","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Apoptosis","Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["Transferase"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA041229"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Monocytes - Unknown function","Tissue expression cluster":"Cluster 37: Intestine - Unknown function","Cell line expression cluster":"Cluster 40: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":["Vesicles"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA041229":"AB_10794194"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.94e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.97e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.13e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.23e-2"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.03e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.77e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.08e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.52e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.52e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"9.23e-2"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.07e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.99e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.43e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.48e-2"},"Tissue RNA - adipose tissue [nTPM]":"29.1","Tissue RNA - adrenal gland [nTPM]":"29.4","Tissue RNA - amygdala [nTPM]":"16.5","Tissue RNA - appendix [nTPM]":"24.4","Tissue RNA - basal ganglia [nTPM]":"15.1","Tissue RNA - bone marrow [nTPM]":"35.0","Tissue RNA - breast [nTPM]":"28.2","Tissue RNA - cerebellum [nTPM]":"18.2","Tissue RNA - cerebral cortex [nTPM]":"23.0","Tissue RNA - cervix [nTPM]":"32.1","Tissue RNA - choroid plexus [nTPM]":"17.0","Tissue RNA - colon [nTPM]":"38.0","Tissue RNA - duodenum [nTPM]":"40.0","Tissue RNA - endometrium 1 [nTPM]":"31.2","Tissue RNA - epididymis [nTPM]":"11.6","Tissue RNA - esophagus [nTPM]":"54.6","Tissue RNA - fallopian tube [nTPM]":"30.4","Tissue RNA - gallbladder [nTPM]":"22.2","Tissue RNA - heart muscle [nTPM]":"21.3","Tissue RNA - hippocampal formation [nTPM]":"17.9","Tissue RNA - hypothalamus [nTPM]":"14.6","Tissue RNA - kidney [nTPM]":"28.1","Tissue RNA - liver [nTPM]":"51.5","Tissue RNA - lung [nTPM]":"33.2","Tissue RNA - lymph node [nTPM]":"22.9","Tissue RNA - medulla oblongata [nTPM]":"17.8","Tissue RNA - midbrain [nTPM]":"15.3","Tissue RNA - ovary [nTPM]":"23.5","Tissue RNA - pancreas [nTPM]":"37.4","Tissue RNA - parathyroid gland [nTPM]":"14.6","Tissue RNA - pituitary gland [nTPM]":"32.1","Tissue RNA - placenta [nTPM]":"20.6","Tissue RNA - pons [nTPM]":"14.8","Tissue RNA - prostate [nTPM]":"27.0","Tissue RNA - rectum [nTPM]":"17.4","Tissue RNA - retina [nTPM]":"8.5","Tissue RNA - salivary gland [nTPM]":"34.7","Tissue RNA - seminal vesicle [nTPM]":"16.5","Tissue RNA - skeletal muscle [nTPM]":"30.4","Tissue RNA - skin 1 [nTPM]":"47.7","Tissue RNA - small intestine [nTPM]":"35.2","Tissue RNA - smooth muscle [nTPM]":"18.8","Tissue RNA - spinal cord [nTPM]":"14.2","Tissue RNA - spleen [nTPM]":"34.5","Tissue RNA - stomach 1 [nTPM]":"35.6","Tissue RNA - testis [nTPM]":"14.8","Tissue RNA - thalamus [nTPM]":"17.7","Tissue RNA - thymus [nTPM]":"19.1","Tissue RNA - thyroid gland [nTPM]":"25.6","Tissue RNA - tongue [nTPM]":"9.9","Tissue RNA - tonsil [nTPM]":"18.6","Tissue RNA - urinary bladder [nTPM]":"34.5","Tissue RNA - vagina [nTPM]":"34.8","Tissue RNA - white matter [nTPM]":"14.3","Cell RNA - A-431 [nTPM]":"57.7","Cell RNA - A549 [nTPM]":"72.2","Cell RNA - AF22 [nTPM]":"40.3","Cell RNA - AN3-CA [nTPM]":"72.5","Cell RNA - ASC diff [nTPM]":"40.8","Cell RNA - ASC TERT1 [nTPM]":"76.5","Cell RNA - BEWO [nTPM]":"47.4","Cell RNA - BJ [nTPM]":"43.4","Cell RNA - BJ hTERT+ [nTPM]":"53.9","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"49.9","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"44.6","Cell RNA - CACO-2 [nTPM]":"88.2","Cell RNA - CAPAN-2 [nTPM]":"72.1","Cell RNA - Daudi [nTPM]":"36.6","Cell RNA - EFO-21 [nTPM]":"50.2","Cell RNA - fHDF\/TERT166 [nTPM]":"55.4","Cell RNA - GAMG [nTPM]":"31.8","Cell RNA - HaCaT [nTPM]":"65.9","Cell RNA - HAP1 [nTPM]":"38.1","Cell RNA - HBEC3-KT [nTPM]":"76.8","Cell RNA - HBF TERT88 [nTPM]":"18.8","Cell RNA - HDLM-2 [nTPM]":"58.3","Cell RNA - HEK 293 [nTPM]":"48.8","Cell RNA - HEL [nTPM]":"52.4","Cell RNA - HeLa [nTPM]":"98.5","Cell RNA - Hep G2 [nTPM]":"68.3","Cell RNA - HHSteC [nTPM]":"53.8","Cell RNA - HL-60 [nTPM]":"56.3","Cell RNA - HMC-1 [nTPM]":"72.7","Cell RNA - HSkMC [nTPM]":"76.2","Cell RNA - hTCEpi [nTPM]":"62.8","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"48.1","Cell RNA - hTERT-HME1 [nTPM]":"62.6","Cell RNA - hTERT-RPE1 [nTPM]":"41.0","Cell RNA - HUVEC TERT2 [nTPM]":"97.4","Cell RNA - JURKAT [nTPM]":"70.6","Cell RNA - K-562 [nTPM]":"57.1","Cell RNA - Karpas-707 [nTPM]":"47.9","Cell RNA - LHCN-M2 [nTPM]":"48.2","Cell RNA - MCF7 [nTPM]":"131.1","Cell RNA - MOLT-4 [nTPM]":"58.3","Cell RNA - NB-4 [nTPM]":"65.2","Cell RNA - NTERA-2 [nTPM]":"79.7","Cell RNA - OE19 [nTPM]":"78.7","Cell RNA - PC-3 [nTPM]":"34.8","Cell RNA - REH [nTPM]":"107.4","Cell RNA - RH-30 [nTPM]":"66.7","Cell RNA - RPMI-8226 [nTPM]":"74.2","Cell RNA - RPTEC TERT1 [nTPM]":"40.2","Cell RNA - RT4 [nTPM]":"30.4","Cell RNA - SCLC-21H [nTPM]":"80.9","Cell RNA - SH-SY5Y [nTPM]":"67.2","Cell RNA - SiHa [nTPM]":"36.3","Cell RNA - SK-BR-3 [nTPM]":"68.5","Cell RNA - SK-MEL-30 [nTPM]":"48.6","Cell RNA - SuSa [nTPM]":"20.9","Cell RNA - T-47d [nTPM]":"78.1","Cell RNA - THP-1 [nTPM]":"68.2","Cell RNA - TIME [nTPM]":"74.3","Cell RNA - U-138 MG [nTPM]":"60.2","Cell RNA - U-2 OS [nTPM]":"83.9","Cell RNA - U-2197 [nTPM]":"56.7","Cell RNA - U-251 MG [nTPM]":"48.2","Cell RNA - U-266\/70 [nTPM]":"69.2","Cell RNA - U-266\/84 [nTPM]":"55.0","Cell RNA - U-698 [nTPM]":"48.4","Cell RNA - U-87 MG [nTPM]":"34.4","Cell RNA - U-937 [nTPM]":"35.9","Cell RNA - WM-115 [nTPM]":"47.8","Blood RNA - basophil [nTPM]":"4.0","Blood RNA - classical monocyte [nTPM]":"9.1","Blood RNA - eosinophil [nTPM]":"7.3","Blood RNA - gdT-cell [nTPM]":"4.5","Blood RNA - intermediate monocyte [nTPM]":"12.4","Blood RNA - MAIT T-cell [nTPM]":"4.3","Blood RNA - memory B-cell [nTPM]":"5.5","Blood RNA - memory CD4 T-cell [nTPM]":"4.4","Blood RNA - memory CD8 T-cell [nTPM]":"4.7","Blood RNA - myeloid DC [nTPM]":"11.2","Blood RNA - naive B-cell [nTPM]":"3.9","Blood RNA - naive CD4 T-cell [nTPM]":"3.1","Blood RNA - naive CD8 T-cell [nTPM]":"3.8","Blood RNA - neutrophil [nTPM]":"6.2","Blood RNA - NK-cell [nTPM]":"2.9","Blood RNA - non-classical monocyte [nTPM]":"8.9","Blood RNA - plasmacytoid DC [nTPM]":"5.3","Blood RNA - T-reg [nTPM]":"6.5","Blood RNA - total PBMC [nTPM]":"5.3","Brain RNA - amygdala [nTPM]":"16.5","Brain RNA - basal ganglia [nTPM]":"15.1","Brain RNA - cerebellum [nTPM]":"18.2","Brain RNA - cerebral cortex [nTPM]":"23.0","Brain RNA - hippocampal formation [nTPM]":"17.9","Brain RNA - hypothalamus [nTPM]":"14.6","Brain RNA - medulla oblongata [nTPM]":"17.8","Brain RNA - midbrain [nTPM]":"15.3","Brain RNA - pons [nTPM]":"14.8","Brain RNA - spinal cord [nTPM]":"14.2","Brain RNA - thalamus [nTPM]":"17.7","Brain RNA - white matter [nTPM]":"14.3","Single Cell Type RNA - Adipocytes [nTPM]":"18.9","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"9.2","Single Cell Type RNA - Astrocytes [nTPM]":"12.4","Single Cell Type RNA - B-cells [nTPM]":"18.2","Single Cell Type RNA - Basal keratinocytes [nTPM]":"28.8","Single Cell Type RNA - Basal prostatic cells [nTPM]":"21.1","Single Cell Type RNA - Basal respiratory cells [nTPM]":"34.2","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.8","Single Cell Type RNA - Bipolar cells [nTPM]":"15.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"31.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.9","Single Cell Type RNA - Cardiomyocytes [nTPM]":"4.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"21.5","Single Cell Type RNA - Club cells [nTPM]":"20.8","Single Cell Type RNA - Collecting duct cells [nTPM]":"14.7","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"6.2","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"23.5","Single Cell Type RNA - dendritic cells [nTPM]":"17.4","Single Cell Type RNA - Distal enterocytes [nTPM]":"56.4","Single Cell Type RNA - Distal tubular cells [nTPM]":"17.6","Single Cell Type RNA - Ductal cells [nTPM]":"39.0","Single Cell Type RNA - Early spermatids [nTPM]":"5.0","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"23.6","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"34.6","Single Cell Type RNA - Endothelial cells [nTPM]":"26.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"34.0","Single Cell Type RNA - Erythroid cells [nTPM]":"33.6","Single Cell Type RNA - Excitatory neurons [nTPM]":"8.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"59.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"36.3","Single Cell Type RNA - Fibroblasts [nTPM]":"19.0","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"38.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"27.9","Single Cell Type RNA - granulocytes [nTPM]":"9.5","Single Cell Type RNA - Granulosa cells [nTPM]":"22.1","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"26.0","Single Cell Type RNA - Hepatocytes [nTPM]":"32.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"42.2","Single Cell Type RNA - Horizontal cells [nTPM]":"37.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"8.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"38.7","Single Cell Type RNA - Ionocytes [nTPM]":"34.6","Single Cell Type RNA - Kupffer cells [nTPM]":"41.8","Single Cell Type RNA - Langerhans cells [nTPM]":"21.3","Single Cell Type RNA - Late spermatids [nTPM]":"13.1","Single Cell Type RNA - Leydig cells [nTPM]":"24.8","Single Cell Type RNA - Macrophages [nTPM]":"26.8","Single Cell Type RNA - Melanocytes [nTPM]":"10.6","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"33.9","Single Cell Type RNA - Muller glia cells [nTPM]":"12.6","Single Cell Type RNA - NK-cells [nTPM]":"6.2","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"6.6","Single Cell Type RNA - Oligodendrocytes [nTPM]":"4.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"53.0","Single Cell Type RNA - Paneth cells [nTPM]":"43.6","Single Cell Type RNA - Peritubular cells [nTPM]":"22.2","Single Cell Type RNA - Plasma cells [nTPM]":"24.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"33.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"80.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"29.2","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"19.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"10.9","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"11.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"18.3","Single Cell Type RNA - Spermatocytes [nTPM]":"8.5","Single Cell Type RNA - Spermatogonia [nTPM]":"25.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"50.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"32.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"26.7","Single Cell Type RNA - T-cells [nTPM]":"16.0","Single Cell Type RNA - Theca cells [nTPM]":"29.0","Single Cell Type RNA - Undifferentiated cells [nTPM]":"42.5","Single Cell Type RNA - Urothelial cells [nTPM]":"38.5"},{"Gene":"TSPAN31","Gene synonym":["SAS"],"Ensembl":"ENSG00000135452","Gene description":"Tetraspanin 31","Uniprot":["Q12999"],"Chromosome":"12","Position":"57738013-57750219","Protein class":["Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"4","RNA cancer specific FPKM":{"glioma":"54.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"RH-30":"139.8"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA030758","HPA057489"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi apparatus","Cytokinetic bridge","Cytosol"],"Secretome location":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Plasmacytoid DCs - Unknown function","Tissue expression cluster":"Cluster 1: Thyroid gland - Transcription","Cell line expression cluster":"Cluster 31: RH-30 & LHCN-M2 - Muscle contraction","Single cell expression cluster":"Cluster 5: Muller glia cells - Visual perception","Subcellular main location":["Golgi apparatus"],"Subcellular additional location":["Nucleoplasm","Cytokinetic bridge","Cytosol"],"Antibody RRID":{"HPA030758":null,"HPA057489":"AB_2683447"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.66e-2"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.50e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.91e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.82e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.96e-3"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.09e-4"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.31e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.19e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.51e-3"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.31e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.79e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"9.91e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.32e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.58e-1"},"Tissue RNA - adipose tissue [nTPM]":"24.5","Tissue RNA - adrenal gland [nTPM]":"29.7","Tissue RNA - amygdala [nTPM]":"9.0","Tissue RNA - appendix [nTPM]":"11.2","Tissue RNA - basal ganglia [nTPM]":"10.8","Tissue RNA - bone marrow [nTPM]":"5.5","Tissue RNA - breast [nTPM]":"23.1","Tissue RNA - cerebellum [nTPM]":"10.8","Tissue RNA - cerebral cortex [nTPM]":"15.6","Tissue RNA - cervix [nTPM]":"26.2","Tissue RNA - choroid plexus [nTPM]":"11.8","Tissue RNA - colon [nTPM]":"20.5","Tissue RNA - duodenum [nTPM]":"16.4","Tissue RNA - endometrium 1 [nTPM]":"26.2","Tissue RNA - epididymis [nTPM]":"13.2","Tissue RNA - esophagus [nTPM]":"20.4","Tissue RNA - fallopian tube [nTPM]":"25.8","Tissue RNA - gallbladder [nTPM]":"20.9","Tissue RNA - heart muscle [nTPM]":"26.7","Tissue RNA - hippocampal formation [nTPM]":"9.5","Tissue RNA - hypothalamus [nTPM]":"10.3","Tissue RNA - kidney [nTPM]":"26.7","Tissue RNA - liver [nTPM]":"20.9","Tissue RNA - lung [nTPM]":"22.8","Tissue RNA - lymph node [nTPM]":"11.8","Tissue RNA - medulla oblongata [nTPM]":"11.2","Tissue RNA - midbrain [nTPM]":"10.2","Tissue RNA - ovary [nTPM]":"25.6","Tissue RNA - pancreas [nTPM]":"25.2","Tissue RNA - parathyroid gland [nTPM]":"32.7","Tissue RNA - pituitary gland [nTPM]":"24.4","Tissue RNA - placenta [nTPM]":"12.5","Tissue RNA - pons [nTPM]":"11.0","Tissue RNA - prostate [nTPM]":"22.1","Tissue RNA - rectum [nTPM]":"10.7","Tissue RNA - retina [nTPM]":"29.7","Tissue RNA - salivary gland [nTPM]":"25.6","Tissue RNA - seminal vesicle [nTPM]":"13.5","Tissue RNA - skeletal muscle [nTPM]":"21.0","Tissue RNA - skin 1 [nTPM]":"18.6","Tissue RNA - small intestine [nTPM]":"18.5","Tissue RNA - smooth muscle [nTPM]":"8.4","Tissue RNA - spinal cord [nTPM]":"11.1","Tissue RNA - spleen [nTPM]":"20.8","Tissue RNA - stomach 1 [nTPM]":"23.0","Tissue RNA - testis [nTPM]":"8.0","Tissue RNA - thalamus [nTPM]":"9.9","Tissue RNA - thymus [nTPM]":"9.8","Tissue RNA - thyroid gland [nTPM]":"30.2","Tissue RNA - tongue [nTPM]":"21.2","Tissue RNA - tonsil [nTPM]":"8.7","Tissue RNA - urinary bladder [nTPM]":"21.0","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"13.0","Cell RNA - A-431 [nTPM]":"9.5","Cell RNA - A549 [nTPM]":"23.4","Cell RNA - AF22 [nTPM]":"21.1","Cell RNA - AN3-CA [nTPM]":"5.4","Cell RNA - ASC diff [nTPM]":"44.3","Cell RNA - ASC TERT1 [nTPM]":"24.0","Cell RNA - BEWO [nTPM]":"13.5","Cell RNA - BJ [nTPM]":"15.8","Cell RNA - BJ hTERT+ [nTPM]":"11.7","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"4.6","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"5.1","Cell RNA - CACO-2 [nTPM]":"16.7","Cell RNA - CAPAN-2 [nTPM]":"46.4","Cell RNA - Daudi [nTPM]":"7.6","Cell RNA - EFO-21 [nTPM]":"32.7","Cell RNA - fHDF\/TERT166 [nTPM]":"29.0","Cell RNA - GAMG [nTPM]":"9.4","Cell RNA - HaCaT [nTPM]":"17.5","Cell RNA - HAP1 [nTPM]":"5.7","Cell RNA - HBEC3-KT [nTPM]":"26.7","Cell RNA - HBF TERT88 [nTPM]":"10.7","Cell RNA - HDLM-2 [nTPM]":"23.1","Cell RNA - HEK 293 [nTPM]":"15.4","Cell RNA - HEL [nTPM]":"10.7","Cell RNA - HeLa [nTPM]":"18.7","Cell RNA - Hep G2 [nTPM]":"6.6","Cell RNA - HHSteC [nTPM]":"45.2","Cell RNA - HL-60 [nTPM]":"10.6","Cell RNA - HMC-1 [nTPM]":"17.9","Cell RNA - HSkMC [nTPM]":"29.6","Cell RNA - hTCEpi [nTPM]":"30.2","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"13.7","Cell RNA - hTERT-HME1 [nTPM]":"30.3","Cell RNA - hTERT-RPE1 [nTPM]":"22.1","Cell RNA - HUVEC TERT2 [nTPM]":"14.6","Cell RNA - JURKAT [nTPM]":"4.6","Cell RNA - K-562 [nTPM]":"7.5","Cell RNA - Karpas-707 [nTPM]":"19.9","Cell RNA - LHCN-M2 [nTPM]":"19.6","Cell RNA - MCF7 [nTPM]":"19.4","Cell RNA - MOLT-4 [nTPM]":"9.2","Cell RNA - NB-4 [nTPM]":"5.9","Cell RNA - NTERA-2 [nTPM]":"4.3","Cell RNA - OE19 [nTPM]":"18.3","Cell RNA - PC-3 [nTPM]":"7.0","Cell RNA - REH [nTPM]":"10.5","Cell RNA - RH-30 [nTPM]":"139.8","Cell RNA - RPMI-8226 [nTPM]":"20.0","Cell RNA - RPTEC TERT1 [nTPM]":"15.7","Cell RNA - RT4 [nTPM]":"19.0","Cell RNA - SCLC-21H [nTPM]":"6.6","Cell RNA - SH-SY5Y [nTPM]":"16.7","Cell RNA - SiHa [nTPM]":"15.6","Cell RNA - SK-BR-3 [nTPM]":"21.3","Cell RNA - SK-MEL-30 [nTPM]":"10.5","Cell RNA - SuSa [nTPM]":"4.5","Cell RNA - T-47d [nTPM]":"41.1","Cell RNA - THP-1 [nTPM]":"15.8","Cell RNA - TIME [nTPM]":"27.6","Cell RNA - U-138 MG [nTPM]":"11.3","Cell RNA - U-2 OS [nTPM]":"9.5","Cell RNA - U-2197 [nTPM]":"5.6","Cell RNA - U-251 MG [nTPM]":"7.4","Cell RNA - U-266\/70 [nTPM]":"28.9","Cell RNA - U-266\/84 [nTPM]":"8.1","Cell RNA - U-698 [nTPM]":"4.1","Cell RNA - U-87 MG [nTPM]":"32.7","Cell RNA - U-937 [nTPM]":"6.3","Cell RNA - WM-115 [nTPM]":"19.2","Blood RNA - basophil [nTPM]":"25.4","Blood RNA - classical monocyte [nTPM]":"26.3","Blood RNA - eosinophil [nTPM]":"16.4","Blood RNA - gdT-cell [nTPM]":"35.8","Blood RNA - intermediate monocyte [nTPM]":"28.6","Blood RNA - MAIT T-cell [nTPM]":"34.8","Blood RNA - memory B-cell [nTPM]":"31.1","Blood RNA - memory CD4 T-cell [nTPM]":"28.5","Blood RNA - memory CD8 T-cell [nTPM]":"30.7","Blood RNA - myeloid DC [nTPM]":"27.6","Blood RNA - naive B-cell [nTPM]":"31.0","Blood RNA - naive CD4 T-cell [nTPM]":"28.3","Blood RNA - naive CD8 T-cell [nTPM]":"26.2","Blood RNA - neutrophil [nTPM]":"5.8","Blood RNA - NK-cell [nTPM]":"35.4","Blood RNA - non-classical monocyte [nTPM]":"42.0","Blood RNA - plasmacytoid DC [nTPM]":"58.3","Blood RNA - T-reg [nTPM]":"22.1","Blood RNA - total PBMC [nTPM]":"33.0","Brain RNA - amygdala [nTPM]":"9.0","Brain RNA - basal ganglia [nTPM]":"10.8","Brain RNA - cerebellum [nTPM]":"10.8","Brain RNA - cerebral cortex [nTPM]":"15.6","Brain RNA - hippocampal formation [nTPM]":"9.5","Brain RNA - hypothalamus [nTPM]":"10.3","Brain RNA - medulla oblongata [nTPM]":"11.2","Brain RNA - midbrain [nTPM]":"10.2","Brain RNA - pons [nTPM]":"11.0","Brain RNA - spinal cord [nTPM]":"11.1","Brain RNA - thalamus [nTPM]":"9.9","Brain RNA - white matter [nTPM]":"13.0","Single Cell Type RNA - Adipocytes [nTPM]":"37.1","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"48.1","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"32.4","Single Cell Type RNA - Astrocytes [nTPM]":"8.1","Single Cell Type RNA - B-cells [nTPM]":"23.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.2","Single Cell Type RNA - Basal prostatic cells [nTPM]":"46.4","Single Cell Type RNA - Basal respiratory cells [nTPM]":"37.4","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"22.2","Single Cell Type RNA - Bipolar cells [nTPM]":"43.2","Single Cell Type RNA - Breast glandular cells [nTPM]":"32.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"27.4","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"31.4","Single Cell Type RNA - Collecting duct cells [nTPM]":"31.3","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"41.7","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"20.9","Single Cell Type RNA - dendritic cells [nTPM]":"29.8","Single Cell Type RNA - Distal enterocytes [nTPM]":"19.9","Single Cell Type RNA - Distal tubular cells [nTPM]":"9.8","Single Cell Type RNA - Ductal cells [nTPM]":"37.6","Single Cell Type RNA - Early spermatids [nTPM]":"1.2","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"18.5","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"32.5","Single Cell Type RNA - Endothelial cells [nTPM]":"26.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"26.5","Single Cell Type RNA - Erythroid cells [nTPM]":"8.2","Single Cell Type RNA - Excitatory neurons [nTPM]":"9.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"39.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"15.2","Single Cell Type RNA - Fibroblasts [nTPM]":"31.7","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"11.7","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"20.4","Single Cell Type RNA - granulocytes [nTPM]":"45.0","Single Cell Type RNA - Granulosa cells [nTPM]":"28.9","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"22.1","Single Cell Type RNA - Hepatocytes [nTPM]":"21.6","Single Cell Type RNA - Hofbauer cells [nTPM]":"22.4","Single Cell Type RNA - Horizontal cells [nTPM]":"21.9","Single Cell Type RNA - Inhibitory neurons [nTPM]":"9.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"21.6","Single Cell Type RNA - Ionocytes [nTPM]":"32.6","Single Cell Type RNA - Kupffer cells [nTPM]":"18.0","Single Cell Type RNA - Langerhans cells [nTPM]":"16.4","Single Cell Type RNA - Late spermatids [nTPM]":"1.8","Single Cell Type RNA - Leydig cells [nTPM]":"25.7","Single Cell Type RNA - Macrophages [nTPM]":"24.2","Single Cell Type RNA - Melanocytes [nTPM]":"32.0","Single Cell Type RNA - Microglial cells [nTPM]":"8.4","Single Cell Type RNA - monocytes [nTPM]":"21.6","Single Cell Type RNA - Muller glia cells [nTPM]":"62.7","Single Cell Type RNA - NK-cells [nTPM]":"35.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"11.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.3","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"37.6","Single Cell Type RNA - Paneth cells [nTPM]":"20.3","Single Cell Type RNA - Peritubular cells [nTPM]":"17.3","Single Cell Type RNA - Plasma cells [nTPM]":"18.4","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"30.5","Single Cell Type RNA - Proximal enterocytes [nTPM]":"30.6","Single Cell Type RNA - Proximal tubular cells [nTPM]":"18.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"27.9","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.4","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"22.3","Single Cell Type RNA - Smooth muscle cells [nTPM]":"31.9","Single Cell Type RNA - Spermatocytes [nTPM]":"9.2","Single Cell Type RNA - Spermatogonia [nTPM]":"7.7","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"16.1","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"12.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"24.5","Single Cell Type RNA - T-cells [nTPM]":"20.4","Single Cell Type RNA - Theca cells [nTPM]":"35.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"19.4","Single Cell Type RNA - Urothelial cells [nTPM]":"31.8"},{"Gene":"U2AF1","Gene synonym":["RN","RNU2AF1","U2AF35","U2AFBP"],"Ensembl":"ENSG00000160201","Gene description":"U2 small nuclear RNA auxiliary factor 1","Uniprot":["Q01081"],"Chromosome":"21","Position":"43092956-43107570","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Basal keratinocytes":"492.9","Basal respiratory cells":"406.9","Ionocytes":"266.5","Langerhans cells":"374.7","Suprabasal keratinocytes":"433.6"},"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"607.7"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA044833","HPA052083"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Transcription","Tissue expression cluster":"Cluster 59: Non-specific - Translation","Cell line expression cluster":"Cluster 36: HEL - Hemostasis","Single cell expression cluster":"Cluster 48: Smooth muscle cells - ECM organization","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA044833":"AB_10960990","HPA052083":"AB_2681720"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.28e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.98e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.87e-2"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.06e-2"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.76e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.29e-4"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.81e-4"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.42e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.31e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.14e-6"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.08e-1"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.40e-2"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.72e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.26e-2"},"Tissue RNA - adipose tissue [nTPM]":"62.9","Tissue RNA - adrenal gland [nTPM]":"47.6","Tissue RNA - amygdala [nTPM]":"36.8","Tissue RNA - appendix [nTPM]":"31.1","Tissue RNA - basal ganglia [nTPM]":"39.9","Tissue RNA - bone marrow [nTPM]":"85.9","Tissue RNA - breast [nTPM]":"58.7","Tissue RNA - cerebellum [nTPM]":"39.8","Tissue RNA - cerebral cortex [nTPM]":"46.9","Tissue RNA - cervix [nTPM]":"57.6","Tissue RNA - choroid plexus [nTPM]":"38.0","Tissue RNA - colon [nTPM]":"79.3","Tissue RNA - duodenum [nTPM]":"25.8","Tissue RNA - endometrium 1 [nTPM]":"68.9","Tissue RNA - epididymis [nTPM]":"27.8","Tissue RNA - esophagus [nTPM]":"64.3","Tissue RNA - fallopian tube [nTPM]":"60.8","Tissue RNA - gallbladder [nTPM]":"18.7","Tissue RNA - heart muscle [nTPM]":"43.0","Tissue RNA - hippocampal formation [nTPM]":"37.7","Tissue RNA - hypothalamus [nTPM]":"41.1","Tissue RNA - kidney [nTPM]":"42.8","Tissue RNA - liver [nTPM]":"48.0","Tissue RNA - lung [nTPM]":"57.3","Tissue RNA - lymph node [nTPM]":"45.2","Tissue RNA - medulla oblongata [nTPM]":"39.3","Tissue RNA - midbrain [nTPM]":"40.2","Tissue RNA - ovary [nTPM]":"69.3","Tissue RNA - pancreas [nTPM]":"41.8","Tissue RNA - parathyroid gland [nTPM]":"32.7","Tissue RNA - pituitary gland [nTPM]":"60.1","Tissue RNA - placenta [nTPM]":"34.6","Tissue RNA - pons [nTPM]":"38.5","Tissue RNA - prostate [nTPM]":"48.0","Tissue RNA - rectum [nTPM]":"26.8","Tissue RNA - retina [nTPM]":"28.9","Tissue RNA - salivary gland [nTPM]":"49.1","Tissue RNA - seminal vesicle [nTPM]":"40.8","Tissue RNA - skeletal muscle [nTPM]":"74.9","Tissue RNA - skin 1 [nTPM]":"47.5","Tissue RNA - small intestine [nTPM]":"57.2","Tissue RNA - smooth muscle [nTPM]":"35.8","Tissue RNA - spinal cord [nTPM]":"38.3","Tissue RNA - spleen [nTPM]":"65.4","Tissue RNA - stomach 1 [nTPM]":"58.2","Tissue RNA - testis [nTPM]":"54.4","Tissue RNA - thalamus [nTPM]":"38.8","Tissue RNA - thymus [nTPM]":"61.8","Tissue RNA - thyroid gland [nTPM]":"62.6","Tissue RNA - tongue [nTPM]":"24.8","Tissue RNA - tonsil [nTPM]":"55.9","Tissue RNA - urinary bladder [nTPM]":"60.7","Tissue RNA - vagina [nTPM]":"50.7","Tissue RNA - white matter [nTPM]":"40.8","Cell RNA - A-431 [nTPM]":"101.1","Cell RNA - A549 [nTPM]":"27.7","Cell RNA - AF22 [nTPM]":"250.5","Cell RNA - AN3-CA [nTPM]":"71.3","Cell RNA - ASC diff [nTPM]":"28.7","Cell RNA - ASC TERT1 [nTPM]":"38.8","Cell RNA - BEWO [nTPM]":"248.1","Cell RNA - BJ [nTPM]":"88.2","Cell RNA - BJ hTERT+ [nTPM]":"82.4","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"105.4","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"115.3","Cell RNA - CACO-2 [nTPM]":"486.0","Cell RNA - CAPAN-2 [nTPM]":"59.8","Cell RNA - Daudi [nTPM]":"20.8","Cell RNA - EFO-21 [nTPM]":"35.1","Cell RNA - fHDF\/TERT166 [nTPM]":"54.3","Cell RNA - GAMG [nTPM]":"125.6","Cell RNA - HaCaT [nTPM]":"33.0","Cell RNA - HAP1 [nTPM]":"161.1","Cell RNA - HBEC3-KT [nTPM]":"36.3","Cell RNA - HBF TERT88 [nTPM]":"104.9","Cell RNA - HDLM-2 [nTPM]":"114.6","Cell RNA - HEK 293 [nTPM]":"134.0","Cell RNA - HEL [nTPM]":"607.7","Cell RNA - HeLa [nTPM]":"61.2","Cell RNA - Hep G2 [nTPM]":"117.9","Cell RNA - HHSteC [nTPM]":"77.0","Cell RNA - HL-60 [nTPM]":"264.0","Cell RNA - HMC-1 [nTPM]":"115.2","Cell RNA - HSkMC [nTPM]":"45.5","Cell RNA - hTCEpi [nTPM]":"90.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"177.1","Cell RNA - hTERT-HME1 [nTPM]":"100.6","Cell RNA - hTERT-RPE1 [nTPM]":"43.5","Cell RNA - HUVEC TERT2 [nTPM]":"62.8","Cell RNA - JURKAT [nTPM]":"238.0","Cell RNA - K-562 [nTPM]":"105.8","Cell RNA - Karpas-707 [nTPM]":"113.4","Cell RNA - LHCN-M2 [nTPM]":"97.2","Cell RNA - MCF7 [nTPM]":"324.4","Cell RNA - MOLT-4 [nTPM]":"271.1","Cell RNA - NB-4 [nTPM]":"358.1","Cell RNA - NTERA-2 [nTPM]":"287.6","Cell RNA - OE19 [nTPM]":"123.4","Cell RNA - PC-3 [nTPM]":"108.3","Cell RNA - REH [nTPM]":"485.1","Cell RNA - RH-30 [nTPM]":"166.9","Cell RNA - RPMI-8226 [nTPM]":"211.9","Cell RNA - RPTEC TERT1 [nTPM]":"99.8","Cell RNA - RT4 [nTPM]":"15.4","Cell RNA - SCLC-21H [nTPM]":"125.9","Cell RNA - SH-SY5Y [nTPM]":"77.6","Cell RNA - SiHa [nTPM]":"212.6","Cell RNA - SK-BR-3 [nTPM]":"98.6","Cell RNA - SK-MEL-30 [nTPM]":"147.6","Cell RNA - SuSa [nTPM]":"36.5","Cell RNA - T-47d [nTPM]":"125.5","Cell RNA - THP-1 [nTPM]":"147.5","Cell RNA - TIME [nTPM]":"12.1","Cell RNA - U-138 MG [nTPM]":"79.2","Cell RNA - U-2 OS [nTPM]":"59.6","Cell RNA - U-2197 [nTPM]":"82.0","Cell RNA - U-251 MG [nTPM]":"236.3","Cell RNA - U-266\/70 [nTPM]":"191.4","Cell RNA - U-266\/84 [nTPM]":"178.3","Cell RNA - U-698 [nTPM]":"48.8","Cell RNA - U-87 MG [nTPM]":"80.3","Cell RNA - U-937 [nTPM]":"333.6","Cell RNA - WM-115 [nTPM]":"118.6","Blood RNA - basophil [nTPM]":"211.9","Blood RNA - classical monocyte [nTPM]":"141.0","Blood RNA - eosinophil [nTPM]":"153.1","Blood RNA - gdT-cell [nTPM]":"101.2","Blood RNA - intermediate monocyte [nTPM]":"140.4","Blood RNA - MAIT T-cell [nTPM]":"106.7","Blood RNA - memory B-cell [nTPM]":"140.2","Blood RNA - memory CD4 T-cell [nTPM]":"112.7","Blood RNA - memory CD8 T-cell [nTPM]":"95.5","Blood RNA - myeloid DC [nTPM]":"150.4","Blood RNA - naive B-cell [nTPM]":"134.2","Blood RNA - naive CD4 T-cell [nTPM]":"112.9","Blood RNA - naive CD8 T-cell [nTPM]":"109.1","Blood RNA - neutrophil [nTPM]":"213.1","Blood RNA - NK-cell [nTPM]":"93.1","Blood RNA - non-classical monocyte [nTPM]":"196.9","Blood RNA - plasmacytoid DC [nTPM]":"240.7","Blood RNA - T-reg [nTPM]":"149.3","Blood RNA - total PBMC [nTPM]":"188.7","Brain RNA - amygdala [nTPM]":"36.8","Brain RNA - basal ganglia [nTPM]":"39.9","Brain RNA - cerebellum [nTPM]":"39.8","Brain RNA - cerebral cortex [nTPM]":"46.9","Brain RNA - hippocampal formation [nTPM]":"37.7","Brain RNA - hypothalamus [nTPM]":"41.1","Brain RNA - medulla oblongata [nTPM]":"39.3","Brain RNA - midbrain [nTPM]":"40.2","Brain RNA - pons [nTPM]":"38.5","Brain RNA - spinal cord [nTPM]":"38.3","Brain RNA - thalamus [nTPM]":"38.8","Brain RNA - white matter [nTPM]":"40.8","Single Cell Type RNA - Adipocytes [nTPM]":"9.5","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"19.2","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"18.1","Single Cell Type RNA - Astrocytes [nTPM]":"3.9","Single Cell Type RNA - B-cells [nTPM]":"37.8","Single Cell Type RNA - Basal keratinocytes [nTPM]":"492.9","Single Cell Type RNA - Basal prostatic cells [nTPM]":"32.5","Single Cell Type RNA - Basal respiratory cells [nTPM]":"406.9","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"86.6","Single Cell Type RNA - Bipolar cells [nTPM]":"23.9","Single Cell Type RNA - Breast glandular cells [nTPM]":"5.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"2.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"5.0","Single Cell Type RNA - Cholangiocytes [nTPM]":"17.2","Single Cell Type RNA - Club cells [nTPM]":"153.5","Single Cell Type RNA - Collecting duct cells [nTPM]":"1.8","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"43.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"19.5","Single Cell Type RNA - dendritic cells [nTPM]":"15.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"16.5","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"5.2","Single Cell Type RNA - Early spermatids [nTPM]":"3.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"4.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"4.4","Single Cell Type RNA - Endothelial cells [nTPM]":"51.7","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"18.2","Single Cell Type RNA - Erythroid cells [nTPM]":"45.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"5.2","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"6.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"20.7","Single Cell Type RNA - Fibroblasts [nTPM]":"51.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"44.4","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"4.2","Single Cell Type RNA - granulocytes [nTPM]":"28.4","Single Cell Type RNA - Granulosa cells [nTPM]":"3.8","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"31.8","Single Cell Type RNA - Hepatocytes [nTPM]":"16.2","Single Cell Type RNA - Hofbauer cells [nTPM]":"23.2","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"4.6","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"17.0","Single Cell Type RNA - Ionocytes [nTPM]":"266.5","Single Cell Type RNA - Kupffer cells [nTPM]":"33.0","Single Cell Type RNA - Langerhans cells [nTPM]":"374.7","Single Cell Type RNA - Late spermatids [nTPM]":"4.1","Single Cell Type RNA - Leydig cells [nTPM]":"18.3","Single Cell Type RNA - Macrophages [nTPM]":"30.6","Single Cell Type RNA - Melanocytes [nTPM]":"202.7","Single Cell Type RNA - Microglial cells [nTPM]":"4.7","Single Cell Type RNA - monocytes [nTPM]":"19.3","Single Cell Type RNA - Muller glia cells [nTPM]":"13.0","Single Cell Type RNA - NK-cells [nTPM]":"27.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"3.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"6.2","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"4.8","Single Cell Type RNA - Paneth cells [nTPM]":"17.0","Single Cell Type RNA - Peritubular cells [nTPM]":"22.6","Single Cell Type RNA - Plasma cells [nTPM]":"60.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"31.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"43.2","Single Cell Type RNA - Proximal tubular cells [nTPM]":"3.1","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"107.6","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"60.7","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"39.1","Single Cell Type RNA - Smooth muscle cells [nTPM]":"110.7","Single Cell Type RNA - Spermatocytes [nTPM]":"16.4","Single Cell Type RNA - Spermatogonia [nTPM]":"18.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"79.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"433.6","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"23.8","Single Cell Type RNA - T-cells [nTPM]":"46.6","Single Cell Type RNA - Theca cells [nTPM]":"1.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"20.2","Single Cell Type RNA - Urothelial cells [nTPM]":"39.1"},{"Gene":"VHL","Gene synonym":["VHL1"],"Ensembl":"ENSG00000134086","Gene description":"Von Hippel-Lindau tumor suppressor","Uniprot":["P40337"],"Chromosome":"3","Position":"10141778-10153667","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Congenital erythrocytosis","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"BEWO":"146.5"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA031631","HPA031632","HPA068954"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 17: Basophils - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response regulation","Cell line expression cluster":"Cluster 28: BEWO - Transcription regulation","Single cell expression cluster":"Cluster 57: B-cells - Immune response","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA031631":"AB_2673968","HPA031632":"AB_2673969","HPA068954":null},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"9.02e-5"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.46e-3"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.52e-1"},"Pathology prognostics - Glioma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.10e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.33e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"1.32e-5"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.55e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.03e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"4.36e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.82e-3"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.81e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.51e-1"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.84e-4"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.46e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.92e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.28e-3"},"Tissue RNA - adipose tissue [nTPM]":"14.0","Tissue RNA - adrenal gland [nTPM]":"13.7","Tissue RNA - amygdala [nTPM]":"11.5","Tissue RNA - appendix [nTPM]":"21.1","Tissue RNA - basal ganglia [nTPM]":"11.0","Tissue RNA - bone marrow [nTPM]":"27.9","Tissue RNA - breast [nTPM]":"14.7","Tissue RNA - cerebellum [nTPM]":"13.6","Tissue RNA - cerebral cortex [nTPM]":"12.1","Tissue RNA - cervix [nTPM]":"11.8","Tissue RNA - choroid plexus [nTPM]":"6.7","Tissue RNA - colon [nTPM]":"14.8","Tissue RNA - duodenum [nTPM]":"15.7","Tissue RNA - endometrium 1 [nTPM]":"14.1","Tissue RNA - epididymis [nTPM]":"9.8","Tissue RNA - esophagus [nTPM]":"12.3","Tissue RNA - fallopian tube [nTPM]":"13.4","Tissue RNA - gallbladder [nTPM]":"11.5","Tissue RNA - heart muscle [nTPM]":"7.9","Tissue RNA - hippocampal formation [nTPM]":"11.8","Tissue RNA - hypothalamus [nTPM]":"14.9","Tissue RNA - kidney [nTPM]":"12.6","Tissue RNA - liver [nTPM]":"14.1","Tissue RNA - lung [nTPM]":"11.8","Tissue RNA - lymph node [nTPM]":"29.6","Tissue RNA - medulla oblongata [nTPM]":"9.4","Tissue RNA - midbrain [nTPM]":"9.4","Tissue RNA - ovary [nTPM]":"12.6","Tissue RNA - pancreas [nTPM]":"12.7","Tissue RNA - parathyroid gland [nTPM]":"11.7","Tissue RNA - pituitary gland [nTPM]":"9.0","Tissue RNA - placenta [nTPM]":"14.1","Tissue RNA - pons [nTPM]":"9.3","Tissue RNA - prostate [nTPM]":"14.0","Tissue RNA - rectum [nTPM]":"15.7","Tissue RNA - retina [nTPM]":"8.9","Tissue RNA - salivary gland [nTPM]":"14.5","Tissue RNA - seminal vesicle [nTPM]":"10.2","Tissue RNA - skeletal muscle [nTPM]":"11.4","Tissue RNA - skin 1 [nTPM]":"14.2","Tissue RNA - small intestine [nTPM]":"17.2","Tissue RNA - smooth muscle [nTPM]":"12.8","Tissue RNA - spinal cord [nTPM]":"9.6","Tissue RNA - spleen [nTPM]":"22.5","Tissue RNA - stomach 1 [nTPM]":"16.0","Tissue RNA - testis [nTPM]":"13.4","Tissue RNA - thalamus [nTPM]":"16.6","Tissue RNA - thymus [nTPM]":"23.4","Tissue RNA - thyroid gland [nTPM]":"15.8","Tissue RNA - tongue [nTPM]":"7.7","Tissue RNA - tonsil [nTPM]":"29.7","Tissue RNA - urinary bladder [nTPM]":"12.5","Tissue RNA - vagina [nTPM]":"10.9","Tissue RNA - white matter [nTPM]":"12.5","Cell RNA - A-431 [nTPM]":"19.5","Cell RNA - A549 [nTPM]":"18.2","Cell RNA - AF22 [nTPM]":"39.9","Cell RNA - AN3-CA [nTPM]":"24.6","Cell RNA - ASC diff [nTPM]":"36.0","Cell RNA - ASC TERT1 [nTPM]":"27.7","Cell RNA - BEWO [nTPM]":"146.5","Cell RNA - BJ [nTPM]":"16.8","Cell RNA - BJ hTERT+ [nTPM]":"24.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"21.1","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"24.5","Cell RNA - CACO-2 [nTPM]":"21.5","Cell RNA - CAPAN-2 [nTPM]":"23.7","Cell RNA - Daudi [nTPM]":"67.9","Cell RNA - EFO-21 [nTPM]":"22.2","Cell RNA - fHDF\/TERT166 [nTPM]":"23.0","Cell RNA - GAMG [nTPM]":"29.9","Cell RNA - HaCaT [nTPM]":"16.4","Cell RNA - HAP1 [nTPM]":"37.2","Cell RNA - HBEC3-KT [nTPM]":"23.6","Cell RNA - HBF TERT88 [nTPM]":"25.7","Cell RNA - HDLM-2 [nTPM]":"33.0","Cell RNA - HEK 293 [nTPM]":"33.7","Cell RNA - HEL [nTPM]":"52.7","Cell RNA - HeLa [nTPM]":"30.5","Cell RNA - Hep G2 [nTPM]":"30.6","Cell RNA - HHSteC [nTPM]":"34.3","Cell RNA - HL-60 [nTPM]":"47.3","Cell RNA - HMC-1 [nTPM]":"41.3","Cell RNA - HSkMC [nTPM]":"28.1","Cell RNA - hTCEpi [nTPM]":"26.3","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"28.0","Cell RNA - hTERT-HME1 [nTPM]":"35.1","Cell RNA - hTERT-RPE1 [nTPM]":"28.4","Cell RNA - HUVEC TERT2 [nTPM]":"24.6","Cell RNA - JURKAT [nTPM]":"42.5","Cell RNA - K-562 [nTPM]":"48.3","Cell RNA - Karpas-707 [nTPM]":"50.3","Cell RNA - LHCN-M2 [nTPM]":"21.1","Cell RNA - MCF7 [nTPM]":"35.0","Cell RNA - MOLT-4 [nTPM]":"45.5","Cell RNA - NB-4 [nTPM]":"40.9","Cell RNA - NTERA-2 [nTPM]":"26.7","Cell RNA - OE19 [nTPM]":"21.1","Cell RNA - PC-3 [nTPM]":"23.4","Cell RNA - REH [nTPM]":"57.3","Cell RNA - RH-30 [nTPM]":"34.6","Cell RNA - RPMI-8226 [nTPM]":"34.6","Cell RNA - RPTEC TERT1 [nTPM]":"25.5","Cell RNA - RT4 [nTPM]":"48.7","Cell RNA - SCLC-21H [nTPM]":"15.0","Cell RNA - SH-SY5Y [nTPM]":"49.4","Cell RNA - SiHa [nTPM]":"35.0","Cell RNA - SK-BR-3 [nTPM]":"18.7","Cell RNA - SK-MEL-30 [nTPM]":"21.0","Cell RNA - SuSa [nTPM]":"23.9","Cell RNA - T-47d [nTPM]":"37.0","Cell RNA - THP-1 [nTPM]":"59.1","Cell RNA - TIME [nTPM]":"21.3","Cell RNA - U-138 MG [nTPM]":"20.8","Cell RNA - U-2 OS [nTPM]":"27.7","Cell RNA - U-2197 [nTPM]":"19.6","Cell RNA - U-251 MG [nTPM]":"26.8","Cell RNA - U-266\/70 [nTPM]":"35.7","Cell RNA - U-266\/84 [nTPM]":"78.1","Cell RNA - U-698 [nTPM]":"105.6","Cell RNA - U-87 MG [nTPM]":"23.2","Cell RNA - U-937 [nTPM]":"55.3","Cell RNA - WM-115 [nTPM]":"19.4","Blood RNA - basophil [nTPM]":"4.6","Blood RNA - classical monocyte [nTPM]":"3.2","Blood RNA - eosinophil [nTPM]":"2.3","Blood RNA - gdT-cell [nTPM]":"2.6","Blood RNA - intermediate monocyte [nTPM]":"2.2","Blood RNA - MAIT T-cell [nTPM]":"1.9","Blood RNA - memory B-cell [nTPM]":"2.5","Blood RNA - memory CD4 T-cell [nTPM]":"1.8","Blood RNA - memory CD8 T-cell [nTPM]":"2.2","Blood RNA - myeloid DC [nTPM]":"2.0","Blood RNA - naive B-cell [nTPM]":"3.3","Blood RNA - naive CD4 T-cell [nTPM]":"1.7","Blood RNA - naive CD8 T-cell [nTPM]":"1.8","Blood RNA - neutrophil [nTPM]":"5.6","Blood RNA - NK-cell [nTPM]":"3.0","Blood RNA - non-classical monocyte [nTPM]":"2.0","Blood RNA - plasmacytoid DC [nTPM]":"2.3","Blood RNA - T-reg [nTPM]":"1.7","Blood RNA - total PBMC [nTPM]":"1.2","Brain RNA - amygdala [nTPM]":"11.5","Brain RNA - basal ganglia [nTPM]":"11.0","Brain RNA - cerebellum [nTPM]":"13.6","Brain RNA - cerebral cortex [nTPM]":"12.1","Brain RNA - hippocampal formation [nTPM]":"11.8","Brain RNA - hypothalamus [nTPM]":"14.9","Brain RNA - medulla oblongata [nTPM]":"9.4","Brain RNA - midbrain [nTPM]":"9.4","Brain RNA - pons [nTPM]":"9.3","Brain RNA - spinal cord [nTPM]":"9.6","Brain RNA - thalamus [nTPM]":"16.6","Brain RNA - white matter [nTPM]":"12.5","Single Cell Type RNA - Adipocytes [nTPM]":"12.4","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"12.8","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"12.5","Single Cell Type RNA - Astrocytes [nTPM]":"9.1","Single Cell Type RNA - B-cells [nTPM]":"38.7","Single Cell Type RNA - Basal keratinocytes [nTPM]":"14.7","Single Cell Type RNA - Basal prostatic cells [nTPM]":"17.8","Single Cell Type RNA - Basal respiratory cells [nTPM]":"14.3","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"24.5","Single Cell Type RNA - Bipolar cells [nTPM]":"14.7","Single Cell Type RNA - Breast glandular cells [nTPM]":"10.7","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"6.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"6.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"20.0","Single Cell Type RNA - Club cells [nTPM]":"9.6","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"18.8","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"16.8","Single Cell Type RNA - dendritic cells [nTPM]":"21.9","Single Cell Type RNA - Distal enterocytes [nTPM]":"10.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"7.9","Single Cell Type RNA - Ductal cells [nTPM]":"11.8","Single Cell Type RNA - Early spermatids [nTPM]":"9.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"13.1","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"26.1","Single Cell Type RNA - Endothelial cells [nTPM]":"14.8","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"14.4","Single Cell Type RNA - Erythroid cells [nTPM]":"30.5","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.9","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"5.1","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"18.7","Single Cell Type RNA - Fibroblasts [nTPM]":"12.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"20.9","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"19.9","Single Cell Type RNA - granulocytes [nTPM]":"5.1","Single Cell Type RNA - Granulosa cells [nTPM]":"18.4","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"18.9","Single Cell Type RNA - Hepatocytes [nTPM]":"14.3","Single Cell Type RNA - Hofbauer cells [nTPM]":"14.9","Single Cell Type RNA - Horizontal cells [nTPM]":"18.5","Single Cell Type RNA - Inhibitory neurons [nTPM]":"14.2","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"11.3","Single Cell Type RNA - Ionocytes [nTPM]":"16.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.1","Single Cell Type RNA - Langerhans cells [nTPM]":"45.8","Single Cell Type RNA - Late spermatids [nTPM]":"7.3","Single Cell Type RNA - Leydig cells [nTPM]":"14.0","Single Cell Type RNA - Macrophages [nTPM]":"32.3","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"7.5","Single Cell Type RNA - monocytes [nTPM]":"31.9","Single Cell Type RNA - Muller glia cells [nTPM]":"9.1","Single Cell Type RNA - NK-cells [nTPM]":"28.8","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"12.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"14.9","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"10.7","Single Cell Type RNA - Paneth cells [nTPM]":"11.7","Single Cell Type RNA - Peritubular cells [nTPM]":"11.3","Single Cell Type RNA - Plasma cells [nTPM]":"33.3","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"23.8","Single Cell Type RNA - Proximal enterocytes [nTPM]":"12.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"9.5","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"9.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"15.3","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"17.4","Single Cell Type RNA - Smooth muscle cells [nTPM]":"11.9","Single Cell Type RNA - Spermatocytes [nTPM]":"15.4","Single Cell Type RNA - Spermatogonia [nTPM]":"24.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"26.7","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"20.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"17.2","Single Cell Type RNA - T-cells [nTPM]":"23.5","Single Cell Type RNA - Theca cells [nTPM]":"21.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"10.2","Single Cell Type RNA - Urothelial cells [nTPM]":"25.9"},{"Gene":"WT1","Gene synonym":["AWT1","GUD","NPHS4","WAGR","WIT-2"],"Ensembl":"ENSG00000184937","Gene description":"WT1 transcription factor","Uniprot":["P19544"],"Chromosome":"11","Position":"32387775-32435564","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":["Cancer-related genes","Disease variant","Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"endometrium 1":"67.6","fallopian tube":"52.3","ovary":"45.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Collecting duct cells":"20.2","Endometrial stromal cells":"70.1","Endothelial cells":"16.3","Granulosa cells":"9.3","Late spermatids":"9.3"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in many","RNA cancer specificity score":"14","RNA cancer specific FPKM":{"ovarian cancer":"55.2"},"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"HEL":"20.7","HMC-1":"29.9","K-562":"19.6","NB-4":"37.2","THP-1":"19.6"},"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["CAB000327","HPA035717","HPA053848"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 89: Fibroblasts - ECM organization","Cell line expression cluster":"Cluster 1: K-562 - Erythropoiesis","Single cell expression cluster":"Cluster 36: Stromal cells - Cell proliferation","Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB000327":"AB_2304486","HPA035717":"AB_2674748","HPA053848":"AB_2682279"},"Pathology prognostics - Breast cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.09e-3"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"9.97e-4"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.32e-1"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.24e-3"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.20e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.98e-3"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.94e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.59e-2"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.23e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"4.15e-2"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.86e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.36e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.31e-10"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.65e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.87e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.96e-3"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.30e-2"},"Tissue RNA - adipose tissue [nTPM]":"26.5","Tissue RNA - adrenal gland [nTPM]":"0.2","Tissue RNA - amygdala [nTPM]":"0.0","Tissue RNA - appendix [nTPM]":"0.5","Tissue RNA - basal ganglia [nTPM]":"0.1","Tissue RNA - bone marrow [nTPM]":"0.0","Tissue RNA - breast [nTPM]":"0.1","Tissue RNA - cerebellum [nTPM]":"0.0","Tissue RNA - cerebral cortex [nTPM]":"0.1","Tissue RNA - cervix [nTPM]":"18.4","Tissue RNA - choroid plexus [nTPM]":"0.0","Tissue RNA - colon [nTPM]":"0.7","Tissue RNA - duodenum [nTPM]":"0.0","Tissue RNA - endometrium 1 [nTPM]":"67.6","Tissue RNA - epididymis [nTPM]":"5.3","Tissue RNA - esophagus [nTPM]":"0.0","Tissue RNA - fallopian tube [nTPM]":"52.3","Tissue RNA - gallbladder [nTPM]":"1.3","Tissue RNA - heart muscle [nTPM]":"4.5","Tissue RNA - hippocampal formation [nTPM]":"0.1","Tissue RNA - hypothalamus [nTPM]":"0.0","Tissue RNA - kidney [nTPM]":"16.3","Tissue RNA - liver [nTPM]":"0.1","Tissue RNA - lung [nTPM]":"0.8","Tissue RNA - lymph node [nTPM]":"0.0","Tissue RNA - medulla oblongata [nTPM]":"0.2","Tissue RNA - midbrain [nTPM]":"0.1","Tissue RNA - ovary [nTPM]":"45.8","Tissue RNA - pancreas [nTPM]":"0.1","Tissue RNA - parathyroid gland [nTPM]":"0.0","Tissue RNA - pituitary gland [nTPM]":"0.0","Tissue RNA - placenta [nTPM]":"1.3","Tissue RNA - pons [nTPM]":"0.0","Tissue RNA - prostate [nTPM]":"0.7","Tissue RNA - rectum [nTPM]":"0.0","Tissue RNA - retina [nTPM]":"0.0","Tissue RNA - salivary gland [nTPM]":"0.0","Tissue RNA - seminal vesicle [nTPM]":"2.9","Tissue RNA - skeletal muscle [nTPM]":"0.0","Tissue RNA - skin 1 [nTPM]":"0.0","Tissue RNA - small intestine [nTPM]":"0.1","Tissue RNA - smooth muscle [nTPM]":"33.1","Tissue RNA - spinal cord [nTPM]":"0.0","Tissue RNA - spleen [nTPM]":"19.0","Tissue RNA - stomach 1 [nTPM]":"0.2","Tissue RNA - testis [nTPM]":"24.2","Tissue RNA - thalamus [nTPM]":"0.0","Tissue RNA - thymus [nTPM]":"0.0","Tissue RNA - thyroid gland [nTPM]":"0.0","Tissue RNA - tongue [nTPM]":"0.0","Tissue RNA - tonsil [nTPM]":"0.0","Tissue RNA - urinary bladder [nTPM]":"0.2","Tissue RNA - vagina [nTPM]":"8.4","Tissue RNA - white matter [nTPM]":"0.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"3.2","Cell RNA - AF22 [nTPM]":"0.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"0.0","Cell RNA - ASC TERT1 [nTPM]":"0.0","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"6.9","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.1","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"8.1","Cell RNA - HBEC3-KT [nTPM]":"0.0","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"8.4","Cell RNA - HEL [nTPM]":"20.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"1.2","Cell RNA - HHSteC [nTPM]":"4.7","Cell RNA - HL-60 [nTPM]":"10.8","Cell RNA - HMC-1 [nTPM]":"29.9","Cell RNA - HSkMC [nTPM]":"0.0","Cell RNA - hTCEpi [nTPM]":"0.0","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"3.4","Cell RNA - hTERT-HME1 [nTPM]":"0.0","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"0.0","Cell RNA - JURKAT [nTPM]":"0.7","Cell RNA - K-562 [nTPM]":"19.6","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"2.0","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"11.2","Cell RNA - NB-4 [nTPM]":"37.2","Cell RNA - NTERA-2 [nTPM]":"0.8","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"6.3","Cell RNA - REH [nTPM]":"1.2","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.0","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.1","Cell RNA - SuSa [nTPM]":"2.9","Cell RNA - T-47d [nTPM]":"2.1","Cell RNA - THP-1 [nTPM]":"19.6","Cell RNA - TIME [nTPM]":"0.2","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"3.3","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.3","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"0.9","Cell RNA - WM-115 [nTPM]":"0.2","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"0.0","Blood RNA - eosinophil [nTPM]":"0.0","Blood RNA - gdT-cell [nTPM]":"0.0","Blood RNA - intermediate monocyte [nTPM]":"0.0","Blood RNA - MAIT T-cell [nTPM]":"0.0","Blood RNA - memory B-cell [nTPM]":"0.0","Blood RNA - memory CD4 T-cell [nTPM]":"0.0","Blood RNA - memory CD8 T-cell [nTPM]":"0.0","Blood RNA - myeloid DC [nTPM]":"0.0","Blood RNA - naive B-cell [nTPM]":"0.0","Blood RNA - naive CD4 T-cell [nTPM]":"0.0","Blood RNA - naive CD8 T-cell [nTPM]":"0.0","Blood RNA - neutrophil [nTPM]":"0.0","Blood RNA - NK-cell [nTPM]":"0.0","Blood RNA - non-classical monocyte [nTPM]":"0.0","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.0","Blood RNA - total PBMC [nTPM]":"0.0","Brain RNA - amygdala [nTPM]":"0.0","Brain RNA - basal ganglia [nTPM]":"0.1","Brain RNA - cerebellum [nTPM]":"0.0","Brain RNA - cerebral cortex [nTPM]":"0.1","Brain RNA - hippocampal formation [nTPM]":"0.1","Brain RNA - hypothalamus [nTPM]":"0.0","Brain RNA - medulla oblongata [nTPM]":"0.2","Brain RNA - midbrain [nTPM]":"0.1","Brain RNA - pons [nTPM]":"0.0","Brain RNA - spinal cord [nTPM]":"0.0","Brain RNA - thalamus [nTPM]":"0.0","Brain RNA - white matter [nTPM]":"0.0","Single Cell Type RNA - Adipocytes [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"0.0","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"0.0","Single Cell Type RNA - Astrocytes [nTPM]":"0.3","Single Cell Type RNA - B-cells [nTPM]":"0.0","Single Cell Type RNA - Basal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Basal prostatic cells [nTPM]":"0.3","Single Cell Type RNA - Basal respiratory cells [nTPM]":"0.0","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Bipolar cells [nTPM]":"0.0","Single Cell Type RNA - Breast glandular cells [nTPM]":"0.0","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"0.0","Single Cell Type RNA - Cardiomyocytes [nTPM]":"1.6","Single Cell Type RNA - Cholangiocytes [nTPM]":"0.0","Single Cell Type RNA - Club cells [nTPM]":"0.0","Single Cell Type RNA - Collecting duct cells [nTPM]":"20.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"1.0","Single Cell Type RNA - dendritic cells [nTPM]":"0.0","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"0.0","Single Cell Type RNA - Ductal cells [nTPM]":"0.0","Single Cell Type RNA - Early spermatids [nTPM]":"3.6","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"2.2","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"70.1","Single Cell Type RNA - Endothelial cells [nTPM]":"16.3","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"0.0","Single Cell Type RNA - Erythroid cells [nTPM]":"0.0","Single Cell Type RNA - Excitatory neurons [nTPM]":"0.1","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.0","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.5","Single Cell Type RNA - Fibroblasts [nTPM]":"7.3","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"0.0","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"1.4","Single Cell Type RNA - granulocytes [nTPM]":"0.0","Single Cell Type RNA - Granulosa cells [nTPM]":"9.3","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"1.4","Single Cell Type RNA - Hepatocytes [nTPM]":"0.0","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.3","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"0.1","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"0.0","Single Cell Type RNA - Ionocytes [nTPM]":"0.0","Single Cell Type RNA - Kupffer cells [nTPM]":"0.0","Single Cell Type RNA - Langerhans cells [nTPM]":"0.0","Single Cell Type RNA - Late spermatids [nTPM]":"9.3","Single Cell Type RNA - Leydig cells [nTPM]":"8.4","Single Cell Type RNA - Macrophages [nTPM]":"0.7","Single Cell Type RNA - Melanocytes [nTPM]":"0.0","Single Cell Type RNA - Microglial cells [nTPM]":"0.0","Single Cell Type RNA - monocytes [nTPM]":"0.0","Single Cell Type RNA - Muller glia cells [nTPM]":"0.0","Single Cell Type RNA - NK-cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"0.0","Single Cell Type RNA - Oligodendrocytes [nTPM]":"0.1","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.0","Single Cell Type RNA - Paneth cells [nTPM]":"0.0","Single Cell Type RNA - Peritubular cells [nTPM]":"1.2","Single Cell Type RNA - Plasma cells [nTPM]":"0.0","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"0.1","Single Cell Type RNA - Proximal enterocytes [nTPM]":"0.0","Single Cell Type RNA - Proximal tubular cells [nTPM]":"2.3","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"0.0","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Sertoli cells [nTPM]":"6.6","Single Cell Type RNA - Skeletal myocytes [nTPM]":"0.0","Single Cell Type RNA - Smooth muscle cells [nTPM]":"2.0","Single Cell Type RNA - Spermatocytes [nTPM]":"4.5","Single Cell Type RNA - Spermatogonia [nTPM]":"1.0","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"0.0","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"0.0","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.8","Single Cell Type RNA - T-cells [nTPM]":"0.5","Single Cell Type RNA - Theca cells [nTPM]":"0.4","Single Cell Type RNA - Undifferentiated cells [nTPM]":"0.0","Single Cell Type RNA - Urothelial cells [nTPM]":"0.1"},{"Gene":"ZBTB16","Gene synonym":["PLZF","ZNF145"],"Ensembl":"ENSG00000109906","Gene description":"Zinc finger and BTB domain containing 16","Uniprot":["Q05516"],"Chromosome":"11","Position":"114059711-114256765","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Mental retardation","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"tongue":"105.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":{"Excitatory neurons":"134.8","Inhibitory neurons":"125.9","NK-cells":"119.4","Skeletal myocytes":"163.9"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific FPKM":{"prostate cancer":"5.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"23.3","MAIT T-cell":"39.4","naive B-cell":"11.0","NK-cell":"10.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"11.0","NK-cells":"10.9","T-cells":"39.4"},"RNA cell line specificity":"Cell line enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"ASC diff":"71.5","ASC TERT1":"38.6","HEL":"40.7","HHSteC":"26.6","HSkMC":"26.7","hTCEpi":"30.6","hTERT-HME1":"25.6"},"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":["HPA001499","CAB004540"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 16: MAIT-cells - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Ribosome","Cell line expression cluster":"Cluster 34: Mesenchymal cell lines - ECM organization","Single cell expression cluster":"Cluster 50: Fibroblasts - ECM organization","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB004540":"AB_2218941","HPA001499":"AB_1079640"},"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"2.21e-1"},"Pathology prognostics - Cervical cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.17e-1"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.30e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.53e-1"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"3.05e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.25e-2"},"Pathology prognostics - Lung cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.40e-1"},"Pathology prognostics - Melanoma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.09e-1"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.79e-4"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.68e-1"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.18e-1"},"Pathology prognostics - Renal cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.21e-4"},"Pathology prognostics - Stomach cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.57e-3"},"Pathology prognostics - Testis cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.67e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.00e-1"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"5.90e-2"},"Tissue RNA - adipose tissue [nTPM]":"55.8","Tissue RNA - adrenal gland [nTPM]":"20.8","Tissue RNA - amygdala [nTPM]":"5.1","Tissue RNA - appendix [nTPM]":"3.4","Tissue RNA - basal ganglia [nTPM]":"14.9","Tissue RNA - bone marrow [nTPM]":"7.6","Tissue RNA - breast [nTPM]":"32.3","Tissue RNA - cerebellum [nTPM]":"11.7","Tissue RNA - cerebral cortex [nTPM]":"24.8","Tissue RNA - cervix [nTPM]":"25.9","Tissue RNA - choroid plexus [nTPM]":"17.7","Tissue RNA - colon [nTPM]":"20.9","Tissue RNA - duodenum [nTPM]":"0.9","Tissue RNA - endometrium 1 [nTPM]":"29.6","Tissue RNA - epididymis [nTPM]":"4.0","Tissue RNA - esophagus [nTPM]":"28.1","Tissue RNA - fallopian tube [nTPM]":"30.9","Tissue RNA - gallbladder [nTPM]":"13.1","Tissue RNA - heart muscle [nTPM]":"28.1","Tissue RNA - hippocampal formation [nTPM]":"9.9","Tissue RNA - hypothalamus [nTPM]":"8.4","Tissue RNA - kidney [nTPM]":"10.6","Tissue RNA - liver [nTPM]":"14.5","Tissue RNA - lung [nTPM]":"27.1","Tissue RNA - lymph node [nTPM]":"8.8","Tissue RNA - medulla oblongata [nTPM]":"20.1","Tissue RNA - midbrain [nTPM]":"8.4","Tissue RNA - ovary [nTPM]":"51.4","Tissue RNA - pancreas [nTPM]":"61.7","Tissue RNA - parathyroid gland [nTPM]":"34.3","Tissue RNA - pituitary gland [nTPM]":"6.4","Tissue RNA - placenta [nTPM]":"9.6","Tissue RNA - pons [nTPM]":"15.2","Tissue RNA - prostate [nTPM]":"15.1","Tissue RNA - rectum [nTPM]":"3.3","Tissue RNA - retina [nTPM]":"2.2","Tissue RNA - salivary gland [nTPM]":"13.3","Tissue RNA - seminal vesicle [nTPM]":"7.0","Tissue RNA - skeletal muscle [nTPM]":"88.6","Tissue RNA - skin 1 [nTPM]":"28.5","Tissue RNA - small intestine [nTPM]":"16.3","Tissue RNA - smooth muscle [nTPM]":"15.8","Tissue RNA - spinal cord [nTPM]":"4.9","Tissue RNA - spleen [nTPM]":"13.2","Tissue RNA - stomach 1 [nTPM]":"18.3","Tissue RNA - testis [nTPM]":"4.0","Tissue RNA - thalamus [nTPM]":"7.1","Tissue RNA - thymus [nTPM]":"6.5","Tissue RNA - thyroid gland [nTPM]":"29.3","Tissue RNA - tongue [nTPM]":"105.8","Tissue RNA - tonsil [nTPM]":"2.0","Tissue RNA - urinary bladder [nTPM]":"29.4","Tissue RNA - vagina [nTPM]":"19.7","Tissue RNA - white matter [nTPM]":"18.0","Cell RNA - A-431 [nTPM]":"0.0","Cell RNA - A549 [nTPM]":"0.0","Cell RNA - AF22 [nTPM]":"13.0","Cell RNA - AN3-CA [nTPM]":"0.0","Cell RNA - ASC diff [nTPM]":"71.5","Cell RNA - ASC TERT1 [nTPM]":"38.6","Cell RNA - BEWO [nTPM]":"0.0","Cell RNA - BJ [nTPM]":"0.0","Cell RNA - BJ hTERT+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"0.0","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"0.0","Cell RNA - CACO-2 [nTPM]":"0.3","Cell RNA - CAPAN-2 [nTPM]":"0.0","Cell RNA - Daudi [nTPM]":"0.0","Cell RNA - EFO-21 [nTPM]":"0.0","Cell RNA - fHDF\/TERT166 [nTPM]":"0.0","Cell RNA - GAMG [nTPM]":"0.0","Cell RNA - HaCaT [nTPM]":"0.0","Cell RNA - HAP1 [nTPM]":"0.0","Cell RNA - HBEC3-KT [nTPM]":"0.6","Cell RNA - HBF TERT88 [nTPM]":"0.0","Cell RNA - HDLM-2 [nTPM]":"0.0","Cell RNA - HEK 293 [nTPM]":"0.5","Cell RNA - HEL [nTPM]":"40.7","Cell RNA - HeLa [nTPM]":"0.0","Cell RNA - Hep G2 [nTPM]":"0.0","Cell RNA - HHSteC [nTPM]":"26.6","Cell RNA - HL-60 [nTPM]":"0.9","Cell RNA - HMC-1 [nTPM]":"0.7","Cell RNA - HSkMC [nTPM]":"26.7","Cell RNA - hTCEpi [nTPM]":"30.6","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"0.0","Cell RNA - hTERT-HME1 [nTPM]":"25.6","Cell RNA - hTERT-RPE1 [nTPM]":"0.0","Cell RNA - HUVEC TERT2 [nTPM]":"4.6","Cell RNA - JURKAT [nTPM]":"5.5","Cell RNA - K-562 [nTPM]":"0.1","Cell RNA - Karpas-707 [nTPM]":"0.0","Cell RNA - LHCN-M2 [nTPM]":"0.8","Cell RNA - MCF7 [nTPM]":"0.0","Cell RNA - MOLT-4 [nTPM]":"2.2","Cell RNA - NB-4 [nTPM]":"9.3","Cell RNA - NTERA-2 [nTPM]":"0.0","Cell RNA - OE19 [nTPM]":"0.0","Cell RNA - PC-3 [nTPM]":"0.0","Cell RNA - REH [nTPM]":"0.0","Cell RNA - RH-30 [nTPM]":"0.0","Cell RNA - RPMI-8226 [nTPM]":"0.0","Cell RNA - RPTEC TERT1 [nTPM]":"0.1","Cell RNA - RT4 [nTPM]":"0.0","Cell RNA - SCLC-21H [nTPM]":"0.0","Cell RNA - SH-SY5Y [nTPM]":"0.0","Cell RNA - SiHa [nTPM]":"0.0","Cell RNA - SK-BR-3 [nTPM]":"0.0","Cell RNA - SK-MEL-30 [nTPM]":"0.0","Cell RNA - SuSa [nTPM]":"0.1","Cell RNA - T-47d [nTPM]":"0.0","Cell RNA - THP-1 [nTPM]":"2.0","Cell RNA - TIME [nTPM]":"8.0","Cell RNA - U-138 MG [nTPM]":"0.0","Cell RNA - U-2 OS [nTPM]":"0.0","Cell RNA - U-2197 [nTPM]":"0.0","Cell RNA - U-251 MG [nTPM]":"0.0","Cell RNA - U-266\/70 [nTPM]":"0.0","Cell RNA - U-266\/84 [nTPM]":"0.0","Cell RNA - U-698 [nTPM]":"0.0","Cell RNA - U-87 MG [nTPM]":"0.0","Cell RNA - U-937 [nTPM]":"1.6","Cell RNA - WM-115 [nTPM]":"0.0","Blood RNA - basophil [nTPM]":"0.0","Blood RNA - classical monocyte [nTPM]":"4.2","Blood RNA - eosinophil [nTPM]":"1.2","Blood RNA - gdT-cell [nTPM]":"23.3","Blood RNA - intermediate monocyte [nTPM]":"1.2","Blood RNA - MAIT T-cell [nTPM]":"39.4","Blood RNA - memory B-cell [nTPM]":"0.4","Blood RNA - memory CD4 T-cell [nTPM]":"1.2","Blood RNA - memory CD8 T-cell [nTPM]":"3.5","Blood RNA - myeloid DC [nTPM]":"0.1","Blood RNA - naive B-cell [nTPM]":"11.0","Blood RNA - naive CD4 T-cell [nTPM]":"1.3","Blood RNA - naive CD8 T-cell [nTPM]":"0.6","Blood RNA - neutrophil [nTPM]":"0.3","Blood RNA - NK-cell [nTPM]":"10.9","Blood RNA - non-classical monocyte [nTPM]":"1.2","Blood RNA - plasmacytoid DC [nTPM]":"0.0","Blood RNA - T-reg [nTPM]":"0.4","Blood RNA - total PBMC [nTPM]":"5.7","Brain RNA - amygdala [nTPM]":"5.1","Brain RNA - basal ganglia [nTPM]":"14.9","Brain RNA - cerebellum [nTPM]":"11.7","Brain RNA - cerebral cortex [nTPM]":"24.8","Brain RNA - hippocampal formation [nTPM]":"9.9","Brain RNA - hypothalamus [nTPM]":"8.4","Brain RNA - medulla oblongata [nTPM]":"20.1","Brain RNA - midbrain [nTPM]":"8.4","Brain RNA - pons [nTPM]":"15.2","Brain RNA - spinal cord [nTPM]":"4.9","Brain RNA - thalamus [nTPM]":"7.1","Brain RNA - white matter [nTPM]":"18.0","Single Cell Type RNA - Adipocytes [nTPM]":"95.3","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"22.4","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"7.7","Single Cell Type RNA - Astrocytes [nTPM]":"59.1","Single Cell Type RNA - B-cells [nTPM]":"16.3","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.1","Single Cell Type RNA - Basal prostatic cells [nTPM]":"81.7","Single Cell Type RNA - Basal respiratory cells [nTPM]":"7.7","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"8.6","Single Cell Type RNA - Bipolar cells [nTPM]":"32.6","Single Cell Type RNA - Breast glandular cells [nTPM]":"12.6","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"16.8","Single Cell Type RNA - Cardiomyocytes [nTPM]":"35.1","Single Cell Type RNA - Cholangiocytes [nTPM]":"42.9","Single Cell Type RNA - Club cells [nTPM]":"7.1","Single Cell Type RNA - Collecting duct cells [nTPM]":"9.2","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"0.0","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"0.1","Single Cell Type RNA - dendritic cells [nTPM]":"51.2","Single Cell Type RNA - Distal enterocytes [nTPM]":"0.7","Single Cell Type RNA - Distal tubular cells [nTPM]":"1.9","Single Cell Type RNA - Ductal cells [nTPM]":"1.9","Single Cell Type RNA - Early spermatids [nTPM]":"21.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"1.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"41.3","Single Cell Type RNA - Endothelial cells [nTPM]":"49.5","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"7.2","Single Cell Type RNA - Erythroid cells [nTPM]":"18.1","Single Cell Type RNA - Excitatory neurons [nTPM]":"134.8","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"0.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"0.2","Single Cell Type RNA - Fibroblasts [nTPM]":"59.8","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"1.1","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"3.8","Single Cell Type RNA - granulocytes [nTPM]":"14.5","Single Cell Type RNA - Granulosa cells [nTPM]":"38.2","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"65.7","Single Cell Type RNA - Hepatocytes [nTPM]":"50.9","Single Cell Type RNA - Hofbauer cells [nTPM]":"0.8","Single Cell Type RNA - Horizontal cells [nTPM]":"0.0","Single Cell Type RNA - Inhibitory neurons [nTPM]":"125.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"3.7","Single Cell Type RNA - Ionocytes [nTPM]":"8.2","Single Cell Type RNA - Kupffer cells [nTPM]":"27.0","Single Cell Type RNA - Langerhans cells [nTPM]":"5.3","Single Cell Type RNA - Late spermatids [nTPM]":"27.7","Single Cell Type RNA - Leydig cells [nTPM]":"89.8","Single Cell Type RNA - Macrophages [nTPM]":"32.1","Single Cell Type RNA - Melanocytes [nTPM]":"7.2","Single Cell Type RNA - Microglial cells [nTPM]":"65.6","Single Cell Type RNA - monocytes [nTPM]":"7.6","Single Cell Type RNA - Muller glia cells [nTPM]":"20.2","Single Cell Type RNA - NK-cells [nTPM]":"119.4","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"45.8","Single Cell Type RNA - Oligodendrocytes [nTPM]":"43.4","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"0.3","Single Cell Type RNA - Paneth cells [nTPM]":"0.1","Single Cell Type RNA - Peritubular cells [nTPM]":"92.2","Single Cell Type RNA - Plasma cells [nTPM]":"17.7","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"38.6","Single Cell Type RNA - Proximal enterocytes [nTPM]":"28.8","Single Cell Type RNA - Proximal tubular cells [nTPM]":"6.6","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"6.8","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"1.9","Single Cell Type RNA - Sertoli cells [nTPM]":"105.2","Single Cell Type RNA - Skeletal myocytes [nTPM]":"163.9","Single Cell Type RNA - Smooth muscle cells [nTPM]":"75.3","Single Cell Type RNA - Spermatocytes [nTPM]":"0.4","Single Cell Type RNA - Spermatogonia [nTPM]":"9.9","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"1.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"6.8","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"0.3","Single Cell Type RNA - T-cells [nTPM]":"27.8","Single Cell Type RNA - Theca cells [nTPM]":"0.2","Single Cell Type RNA - Undifferentiated cells [nTPM]":"3.5","Single Cell Type RNA - Urothelial cells [nTPM]":"9.4"},{"Gene":"ZRSR2","Gene synonym":["U2AF1-RS2","U2AF1L2","URP","ZC3H22"],"Ensembl":"ENSG00000169249","Gene description":"Zinc finger CCCH-type, RNA binding motif and serine\/arginine rich 2","Uniprot":["Q15696"],"Chromosome":"X","Position":"15790472-15823260","Protein class":["Cancer-related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing"],"Molecular function":["Ribonucleoprotein","RNA-binding"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nTPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific FPKM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cell line specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 26: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 76: Brain & Bone marrow - Chromatin organization","Cell line expression cluster":"Cluster 26: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 7: Non-specific - Mitochondria","Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Pathology prognostics - Breast cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"7.96e-4"},"Pathology prognostics - Cervical cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.54e-2"},"Pathology prognostics - Colorectal cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"7.31e-2"},"Pathology prognostics - Endometrial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"8.50e-5"},"Pathology prognostics - Glioma":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"8.08e-2"},"Pathology prognostics - Head and neck cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"1.69e-1"},"Pathology prognostics - Liver cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"6.14e-3"},"Pathology prognostics - Lung cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"5.72e-3"},"Pathology prognostics - Melanoma":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.46e-2"},"Pathology prognostics - Ovarian cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.47e-3"},"Pathology prognostics - Pancreatic cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"6.90e-2"},"Pathology prognostics - Prostate cancer":{"prognostic type":"unfavorable","is_prognostic":false,"p_val":"2.85e-2"},"Pathology prognostics - Renal cancer":{"prognostic type":"unfavorable","is_prognostic":true,"p_val":"4.87e-5"},"Pathology prognostics - Stomach cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"8.14e-2"},"Pathology prognostics - Testis cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"3.04e-1"},"Pathology prognostics - Thyroid cancer":{"prognostic type":"favorable","is_prognostic":false,"p_val":"1.65e-2"},"Pathology prognostics - Urothelial cancer":{"prognostic type":"favorable","is_prognostic":true,"p_val":"2.97e-4"},"Tissue RNA - adipose tissue [nTPM]":"15.2","Tissue RNA - adrenal gland [nTPM]":"12.1","Tissue RNA - amygdala [nTPM]":"25.7","Tissue RNA - appendix [nTPM]":"17.3","Tissue RNA - basal ganglia [nTPM]":"25.1","Tissue RNA - bone marrow [nTPM]":"42.7","Tissue RNA - breast [nTPM]":"16.2","Tissue RNA - cerebellum [nTPM]":"28.8","Tissue RNA - cerebral cortex [nTPM]":"36.1","Tissue RNA - cervix [nTPM]":"24.3","Tissue RNA - choroid plexus [nTPM]":"26.5","Tissue RNA - colon [nTPM]":"22.9","Tissue RNA - duodenum [nTPM]":"11.0","Tissue RNA - endometrium 1 [nTPM]":"21.3","Tissue RNA - epididymis [nTPM]":"20.2","Tissue RNA - esophagus [nTPM]":"13.4","Tissue RNA - fallopian tube [nTPM]":"20.2","Tissue RNA - gallbladder [nTPM]":"10.2","Tissue RNA - heart muscle [nTPM]":"17.2","Tissue RNA - hippocampal formation [nTPM]":"24.4","Tissue RNA - hypothalamus [nTPM]":"27.5","Tissue RNA - kidney [nTPM]":"16.2","Tissue RNA - liver [nTPM]":"13.3","Tissue RNA - lung [nTPM]":"20.1","Tissue RNA - lymph node [nTPM]":"29.0","Tissue RNA - medulla oblongata [nTPM]":"25.9","Tissue RNA - midbrain [nTPM]":"24.9","Tissue RNA - ovary [nTPM]":"22.2","Tissue RNA - pancreas [nTPM]":"14.3","Tissue RNA - parathyroid gland [nTPM]":"13.0","Tissue RNA - pituitary gland [nTPM]":"24.1","Tissue RNA - placenta [nTPM]":"10.8","Tissue RNA - pons [nTPM]":"24.9","Tissue RNA - prostate [nTPM]":"18.1","Tissue RNA - rectum [nTPM]":"12.5","Tissue RNA - retina [nTPM]":"22.2","Tissue RNA - salivary gland [nTPM]":"13.9","Tissue RNA - seminal vesicle [nTPM]":"11.9","Tissue RNA - skeletal muscle [nTPM]":"20.4","Tissue RNA - skin 1 [nTPM]":"15.4","Tissue RNA - small intestine [nTPM]":"19.8","Tissue RNA - smooth muscle [nTPM]":"17.0","Tissue RNA - spinal cord [nTPM]":"23.2","Tissue RNA - spleen [nTPM]":"31.8","Tissue RNA - stomach 1 [nTPM]":"14.8","Tissue RNA - testis [nTPM]":"5.6","Tissue RNA - thalamus [nTPM]":"26.0","Tissue RNA - thymus [nTPM]":"21.9","Tissue RNA - thyroid gland [nTPM]":"17.4","Tissue RNA - tongue [nTPM]":"13.1","Tissue RNA - tonsil [nTPM]":"20.2","Tissue RNA - urinary bladder [nTPM]":"18.1","Tissue RNA - vagina [nTPM]":"20.1","Tissue RNA - white matter [nTPM]":"26.3","Cell RNA - A-431 [nTPM]":"14.3","Cell RNA - A549 [nTPM]":"8.9","Cell RNA - AF22 [nTPM]":"15.6","Cell RNA - AN3-CA [nTPM]":"14.7","Cell RNA - ASC diff [nTPM]":"21.9","Cell RNA - ASC TERT1 [nTPM]":"18.4","Cell RNA - BEWO [nTPM]":"6.1","Cell RNA - BJ [nTPM]":"11.4","Cell RNA - BJ hTERT+ [nTPM]":"10.5","Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]":"10.8","Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]":"11.0","Cell RNA - CACO-2 [nTPM]":"11.3","Cell RNA - CAPAN-2 [nTPM]":"11.3","Cell RNA - Daudi [nTPM]":"16.1","Cell RNA - EFO-21 [nTPM]":"19.2","Cell RNA - fHDF\/TERT166 [nTPM]":"10.6","Cell RNA - GAMG [nTPM]":"28.3","Cell RNA - HaCaT [nTPM]":"13.7","Cell RNA - HAP1 [nTPM]":"15.6","Cell RNA - HBEC3-KT [nTPM]":"19.9","Cell RNA - HBF TERT88 [nTPM]":"11.0","Cell RNA - HDLM-2 [nTPM]":"12.3","Cell RNA - HEK 293 [nTPM]":"20.0","Cell RNA - HEL [nTPM]":"10.4","Cell RNA - HeLa [nTPM]":"22.8","Cell RNA - Hep G2 [nTPM]":"10.1","Cell RNA - HHSteC [nTPM]":"14.8","Cell RNA - HL-60 [nTPM]":"24.4","Cell RNA - HMC-1 [nTPM]":"23.9","Cell RNA - HSkMC [nTPM]":"9.2","Cell RNA - hTCEpi [nTPM]":"17.7","Cell RNA - hTEC\/SVTERT24-B [nTPM]":"20.0","Cell RNA - hTERT-HME1 [nTPM]":"32.4","Cell RNA - hTERT-RPE1 [nTPM]":"21.3","Cell RNA - HUVEC TERT2 [nTPM]":"18.9","Cell RNA - JURKAT [nTPM]":"15.5","Cell RNA - K-562 [nTPM]":"17.0","Cell RNA - Karpas-707 [nTPM]":"15.3","Cell RNA - LHCN-M2 [nTPM]":"12.9","Cell RNA - MCF7 [nTPM]":"17.5","Cell RNA - MOLT-4 [nTPM]":"13.0","Cell RNA - NB-4 [nTPM]":"25.4","Cell RNA - NTERA-2 [nTPM]":"20.1","Cell RNA - OE19 [nTPM]":"7.5","Cell RNA - PC-3 [nTPM]":"12.7","Cell RNA - REH [nTPM]":"15.1","Cell RNA - RH-30 [nTPM]":"22.0","Cell RNA - RPMI-8226 [nTPM]":"16.4","Cell RNA - RPTEC TERT1 [nTPM]":"12.9","Cell RNA - RT4 [nTPM]":"11.0","Cell RNA - SCLC-21H [nTPM]":"10.6","Cell RNA - SH-SY5Y [nTPM]":"11.8","Cell RNA - SiHa [nTPM]":"26.7","Cell RNA - SK-BR-3 [nTPM]":"23.5","Cell RNA - SK-MEL-30 [nTPM]":"17.7","Cell RNA - SuSa [nTPM]":"21.4","Cell RNA - T-47d [nTPM]":"18.4","Cell RNA - THP-1 [nTPM]":"13.6","Cell RNA - TIME [nTPM]":"13.2","Cell RNA - U-138 MG [nTPM]":"10.7","Cell RNA - U-2 OS [nTPM]":"7.8","Cell RNA - U-2197 [nTPM]":"28.7","Cell RNA - U-251 MG [nTPM]":"11.0","Cell RNA - U-266\/70 [nTPM]":"12.9","Cell RNA - U-266\/84 [nTPM]":"11.7","Cell RNA - U-698 [nTPM]":"15.0","Cell RNA - U-87 MG [nTPM]":"8.2","Cell RNA - U-937 [nTPM]":"17.0","Cell RNA - WM-115 [nTPM]":"14.2","Blood RNA - basophil [nTPM]":"38.7","Blood RNA - classical monocyte [nTPM]":"25.7","Blood RNA - eosinophil [nTPM]":"24.0","Blood RNA - gdT-cell [nTPM]":"17.3","Blood RNA - intermediate monocyte [nTPM]":"22.6","Blood RNA - MAIT T-cell [nTPM]":"17.2","Blood RNA - memory B-cell [nTPM]":"34.9","Blood RNA - memory CD4 T-cell [nTPM]":"21.6","Blood RNA - memory CD8 T-cell [nTPM]":"23.2","Blood RNA - myeloid DC [nTPM]":"15.1","Blood RNA - naive B-cell [nTPM]":"37.2","Blood RNA - naive CD4 T-cell [nTPM]":"26.1","Blood RNA - naive CD8 T-cell [nTPM]":"18.5","Blood RNA - neutrophil [nTPM]":"26.9","Blood RNA - NK-cell [nTPM]":"14.3","Blood RNA - non-classical monocyte [nTPM]":"22.9","Blood RNA - plasmacytoid DC [nTPM]":"24.6","Blood RNA - T-reg [nTPM]":"24.3","Blood RNA - total PBMC [nTPM]":"10.5","Brain RNA - amygdala [nTPM]":"25.7","Brain RNA - basal ganglia [nTPM]":"25.1","Brain RNA - cerebellum [nTPM]":"28.8","Brain RNA - cerebral cortex [nTPM]":"36.1","Brain RNA - hippocampal formation [nTPM]":"24.4","Brain RNA - hypothalamus [nTPM]":"27.5","Brain RNA - medulla oblongata [nTPM]":"25.9","Brain RNA - midbrain [nTPM]":"24.9","Brain RNA - pons [nTPM]":"24.9","Brain RNA - spinal cord [nTPM]":"23.2","Brain RNA - thalamus [nTPM]":"26.0","Brain RNA - white matter [nTPM]":"26.3","Single Cell Type RNA - Adipocytes [nTPM]":"16.7","Single Cell Type RNA - Alveolar cells type 1 [nTPM]":"9.6","Single Cell Type RNA - Alveolar cells type 2 [nTPM]":"17.4","Single Cell Type RNA - Astrocytes [nTPM]":"12.1","Single Cell Type RNA - B-cells [nTPM]":"35.6","Single Cell Type RNA - Basal keratinocytes [nTPM]":"11.3","Single Cell Type RNA - Basal prostatic cells [nTPM]":"10.2","Single Cell Type RNA - Basal respiratory cells [nTPM]":"16.6","Single Cell Type RNA - Basal squamous epithelial cells [nTPM]":"12.0","Single Cell Type RNA - Bipolar cells [nTPM]":"15.3","Single Cell Type RNA - Breast glandular cells [nTPM]":"13.8","Single Cell Type RNA - Breast myoepithelial cells [nTPM]":"12.1","Single Cell Type RNA - Cardiomyocytes [nTPM]":"23.9","Single Cell Type RNA - Cholangiocytes [nTPM]":"5.7","Single Cell Type RNA - Club cells [nTPM]":"17.2","Single Cell Type RNA - Collecting duct cells [nTPM]":"16.5","Single Cell Type RNA - Cone photoreceptor cells [nTPM]":"14.6","Single Cell Type RNA - Cytotrophoblasts [nTPM]":"6.8","Single Cell Type RNA - dendritic cells [nTPM]":"42.3","Single Cell Type RNA - Distal enterocytes [nTPM]":"14.0","Single Cell Type RNA - Distal tubular cells [nTPM]":"23.5","Single Cell Type RNA - Ductal cells [nTPM]":"12.8","Single Cell Type RNA - Early spermatids [nTPM]":"1.1","Single Cell Type RNA - Endometrial ciliated cells [nTPM]":"27.7","Single Cell Type RNA - Endometrial stromal cells [nTPM]":"14.3","Single Cell Type RNA - Endothelial cells [nTPM]":"14.2","Single Cell Type RNA - Enteroendocrine cells [nTPM]":"16.8","Single Cell Type RNA - Erythroid cells [nTPM]":"9.9","Single Cell Type RNA - Excitatory neurons [nTPM]":"15.5","Single Cell Type RNA - Exocrine glandular cells [nTPM]":"14.9","Single Cell Type RNA - Extravillous trophoblasts [nTPM]":"10.2","Single Cell Type RNA - Fibroblasts [nTPM]":"11.5","Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]":"4.6","Single Cell Type RNA - Glandular and luminal cells [nTPM]":"14.1","Single Cell Type RNA - granulocytes [nTPM]":"32.3","Single Cell Type RNA - Granulosa cells [nTPM]":"9.7","Single Cell Type RNA - Hepatic stellate cells [nTPM]":"11.0","Single Cell Type RNA - Hepatocytes [nTPM]":"13.8","Single Cell Type RNA - Hofbauer cells [nTPM]":"19.1","Single Cell Type RNA - Horizontal cells [nTPM]":"8.4","Single Cell Type RNA - Inhibitory neurons [nTPM]":"17.9","Single Cell Type RNA - Intestinal goblet cells [nTPM]":"16.9","Single Cell Type RNA - Ionocytes [nTPM]":"22.4","Single Cell Type RNA - Kupffer cells [nTPM]":"33.5","Single Cell Type RNA - Langerhans cells [nTPM]":"19.6","Single Cell Type RNA - Late spermatids [nTPM]":"1.6","Single Cell Type RNA - Leydig cells [nTPM]":"13.7","Single Cell Type RNA - Macrophages [nTPM]":"25.6","Single Cell Type RNA - Melanocytes [nTPM]":"12.4","Single Cell Type RNA - Microglial cells [nTPM]":"14.0","Single Cell Type RNA - monocytes [nTPM]":"30.5","Single Cell Type RNA - Muller glia cells [nTPM]":"9.6","Single Cell Type RNA - NK-cells [nTPM]":"37.0","Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]":"10.1","Single Cell Type RNA - Oligodendrocytes [nTPM]":"13.7","Single Cell Type RNA - Pancreatic endocrine cells [nTPM]":"13.1","Single Cell Type RNA - Paneth cells [nTPM]":"8.2","Single Cell Type RNA - Peritubular cells [nTPM]":"16.6","Single Cell Type RNA - Plasma cells [nTPM]":"18.8","Single Cell Type RNA - Prostatic glandular cells [nTPM]":"7.0","Single Cell Type RNA - Proximal enterocytes [nTPM]":"17.3","Single Cell Type RNA - Proximal tubular cells [nTPM]":"17.7","Single Cell Type RNA - Respiratory ciliated cells [nTPM]":"23.7","Single Cell Type RNA - Rod photoreceptor cells [nTPM]":"19.5","Single Cell Type RNA - Sertoli cells [nTPM]":"19.7","Single Cell Type RNA - Skeletal myocytes [nTPM]":"13.8","Single Cell Type RNA - Smooth muscle cells [nTPM]":"16.2","Single Cell Type RNA - Spermatocytes [nTPM]":"6.4","Single Cell Type RNA - Spermatogonia [nTPM]":"8.3","Single Cell Type RNA - Squamous epithelial cells [nTPM]":"7.8","Single Cell Type RNA - Suprabasal keratinocytes [nTPM]":"10.5","Single Cell Type RNA - Syncytiotrophoblasts [nTPM]":"7.3","Single Cell Type RNA - T-cells [nTPM]":"32.2","Single Cell Type RNA - Theca cells [nTPM]":"9.3","Single Cell Type RNA - Undifferentiated cells [nTPM]":"13.4","Single Cell Type RNA - Urothelial cells [nTPM]":"8.0"}]